-- dump date 20111121_015455 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 579112000001 SEQ_END SEQ_END NC_012578.1 2892523 2892523 DR NC_012578.1; contig end 2892523..2892523 Vibrio cholerae M66-2 579112000002 SEQ_END SEQ_END NC_012580.1 1046382 1046382 DR NC_012580.1; contig end 1046382..1046382 Vibrio cholerae M66-2 YP_002808789.1 CDS VCM66_0001 NC_012578.1 235 402 R hypothetical protein complement(235..402) Vibrio cholerae M66-2 7774083 YP_002808790.1 CDS mioC NC_012578.1 372 806 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(372..806) Vibrio cholerae M66-2 7771300 YP_002808791.1 CDS trmE NC_012578.1 816 2210 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(816..2210) Vibrio cholerae M66-2 7771301 YP_002808792.1 CDS yidC NC_012578.1 2271 3896 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; putative inner membrane protein translocase component YidC complement(2271..3896) Vibrio cholerae M66-2 7771302 YP_002808793.1 CDS VCM66_0005 NC_012578.1 3899 4156 R hypothetical protein complement(3899..4156) Vibrio cholerae M66-2 7771303 YP_002808794.1 CDS rnpA NC_012578.1 4123 4479 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P complement(4123..4479) Vibrio cholerae M66-2 7771304 YP_002808795.1 CDS rpmH NC_012578.1 4492 4629 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(4492..4629) Vibrio cholerae M66-2 7771305 YP_002808796.1 CDS VCM66_0008 NC_012578.1 4871 5608 R amino acid ABC transporter ATP-binding protein complement(4871..5608) Vibrio cholerae M66-2 7771306 YP_002808797.1 CDS VCM66_0009 NC_012578.1 5605 6276 R amino acid ABC transporter permease complement(5605..6276) Vibrio cholerae M66-2 7771307 YP_002808798.1 CDS VCM66_0010 NC_012578.1 6354 7100 R amino acid ABC transporter substrate-binding protein complement(6354..7100) Vibrio cholerae M66-2 7771308 YP_002808799.1 CDS VCM66_0011 NC_012578.1 7224 7352 D hypothetical protein 7224..7352 Vibrio cholerae M66-2 7771309 YP_002808800.1 CDS dnaA NC_012578.1 7397 8815 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 7397..8815 Vibrio cholerae M66-2 7771310 YP_002808801.1 CDS dnaN NC_012578.1 8873 9973 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 8873..9973 Vibrio cholerae M66-2 7771311 YP_002808802.1 CDS recF NC_012578.1 9991 11082 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 9991..11082 Vibrio cholerae M66-2 7771312 YP_002808803.1 CDS gyrB NC_012578.1 11103 13520 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 11103..13520 Vibrio cholerae M66-2 7771313 YP_002808804.1 CDS VCM66_0016 NC_012578.1 13876 14367 D hypothetical protein 13876..14367 Vibrio cholerae M66-2 7771314 YP_002808805.1 CDS VCM66_0017 NC_012578.1 14377 14493 D hypothetical protein 14377..14493 Vibrio cholerae M66-2 7771315 YP_002808806.1 CDS ibpA NC_012578.1 14769 15206 D putative heat shock protein 14769..15206 Vibrio cholerae M66-2 7771316 YP_002808807.1 CDS avtA NC_012578.1 15294 16550 R transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase complement(15294..16550) Vibrio cholerae M66-2 7771317 YP_002808808.1 CDS glyS NC_012578.1 16869 18935 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(16869..18935) Vibrio cholerae M66-2 7771318 YP_002808809.1 CDS glyQ NC_012578.1 18950 19942 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(18950..19942) Vibrio cholerae M66-2 7771319 YP_002808810.1 CDS VCM66_0022 NC_012578.1 20235 20837 D hypothetical protein 20235..20837 Vibrio cholerae M66-2 7771320 YP_002808811.1 CDS VCM66_0023 NC_012578.1 20943 21200 D NADH dehydrogenase subunit II-like protein 20943..21200 Vibrio cholerae M66-2 7771321 YP_002808812.1 CDS VCM66_0024 NC_012578.1 21287 21535 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(21287..21535) Vibrio cholerae M66-2 7771322 YP_002808813.1 CDS VCM66_0025 NC_012578.1 21656 21856 D hypothetical protein 21656..21856 Vibrio cholerae M66-2 7771323 YP_002808814.1 CDS VCM66_0026 NC_012578.1 22028 23008 R zinc-binding alcohol dehydrogenase complement(22028..23008) Vibrio cholerae M66-2 7771324 YP_002808815.1 CDS ilvA NC_012578.1 23256 24788 R threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase complement(23256..24788) Vibrio cholerae M66-2 7771325 YP_002808816.1 CDS ilvD NC_012578.1 24792 26633 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(24792..26633) Vibrio cholerae M66-2 7771326 YP_002808817.1 CDS ilvE NC_012578.1 26643 27602 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(26643..27602) Vibrio cholerae M66-2 7771327 YP_002808818.1 CDS ilvM NC_012578.1 27593 27877 R acetolactate synthase 2 regulatory subunit complement(27593..27877) Vibrio cholerae M66-2 7771328 YP_002808819.1 CDS ilvG NC_012578.1 27889 29535 R catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit complement(27889..29535) Vibrio cholerae M66-2 7771329 YP_002808820.1 CDS VCM66_0032 NC_012578.1 30069 31592 D ComM-like protein 30069..31592 Vibrio cholerae M66-2 7771330 YP_002808821.1 CDS VCM66_0033 NC_012578.1 31682 32566 D putative acyltransferase 31682..32566 Vibrio cholerae M66-2 7771331 YP_002808822.1 CDS tpcG NC_012578.1 32643 33245 R thiol:disulfide interchange protein complement(32643..33245) Vibrio cholerae M66-2 7771332 YP_002808823.1 CDS VCM66_0035 NC_012578.1 33276 34298 R catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase complement(33276..34298) Vibrio cholerae M66-2 7771333 YP_002808824.1 CDS VCM66_0036 NC_012578.1 34310 35797 R FixG-like protein complement(34310..35797) Vibrio cholerae M66-2 7771334 YP_002808825.1 CDS VCM66_0037 NC_012578.1 36151 36429 R hypothetical protein complement(36151..36429) Vibrio cholerae M66-2 7771335 YP_002808826.1 CDS VCM66_0038 NC_012578.1 36526 36693 R hypothetical protein complement(36526..36693) Vibrio cholerae M66-2 7771336 YP_002808827.1 CDS VCM66_0039 NC_012578.1 36927 37769 D SpoOM-like protein 36927..37769 Vibrio cholerae M66-2 7771337 YP_002808828.1 CDS VCM66_0040 NC_012578.1 37847 38494 D putative hemolysin 37847..38494 Vibrio cholerae M66-2 7771338 YP_002808829.1 CDS VCM66_0041 NC_012578.1 38533 39189 R hypothetical protein complement(38533..39189) Vibrio cholerae M66-2 7771339 YP_002808830.1 CDS trkH-1 NC_012578.1 39102 40547 R potassium uptake protein TrkH complement(39102..40547) Vibrio cholerae M66-2 7771340 YP_002808831.1 CDS trkA NC_012578.1 40559 41935 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component complement(40559..41935) Vibrio cholerae M66-2 7771341 YP_002808832.1 CDS sun NC_012578.1 41997 43301 R sun protein complement(41997..43301) Vibrio cholerae M66-2 7771342 YP_002808833.1 CDS fmt NC_012578.1 43333 44280 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(43333..44280) Vibrio cholerae M66-2 7771343 YP_002808834.1 CDS def NC_012578.1 44298 44807 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(44298..44807) Vibrio cholerae M66-2 7771344 YP_002808835.1 CDS VCM66_0047 NC_012578.1 44899 46074 D hypothetical protein 44899..46074 Vibrio cholerae M66-2 7771345 YP_002808836.1 CDS smf NC_012578.1 46074 47189 D smf protein 46074..47189 Vibrio cholerae M66-2 7771346 YP_002808837.1 CDS smg NC_012578.1 47192 47668 D hypothetical protein 47192..47668 Vibrio cholerae M66-2 7771347 YP_002808838.1 CDS VCM66_0050 NC_012578.1 47678 48250 D DNA topoisomerase I-like protein 47678..48250 Vibrio cholerae M66-2 7771348 YP_002808839.1 CDS purK NC_012578.1 48323 49456 R With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit complement(48323..49456) Vibrio cholerae M66-2 7771349 YP_002808840.1 CDS purE NC_012578.1 49460 49945 R phosphoribosylaminoimidazole carboxylase, catalytic subunit complement(49460..49945) Vibrio cholerae M66-2 7771350 YP_002808841.1 CDS VCM66_0053 NC_012578.1 49960 50085 D hypothetical protein 49960..50085 Vibrio cholerae M66-2 7771351 YP_002808842.1 CDS VCM66_0054 NC_012578.1 50103 50669 D Sua5/YciO/YrdC family protein 50103..50669 Vibrio cholerae M66-2 7771352 YP_002808843.1 CDS hemF NC_012578.1 50688 51605 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 50688..51605 Vibrio cholerae M66-2 7771353 YP_002808844.1 CDS aroE NC_012578.1 51667 52503 D AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 51667..52503 Vibrio cholerae M66-2 7771354 YP_002808845.1 CDS VCM66_0057 NC_012578.1 52500 52775 D hypothetical protein 52500..52775 Vibrio cholerae M66-2 7771355 YP_002808846.1 CDS VCM66_0058 NC_012578.1 52756 53310 R carbonic anhydrase, family 3 complement(52756..53310) Vibrio cholerae M66-2 7771356 YP_002808847.1 CDS crcB NC_012578.1 59321 59701 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 59321..59701 Vibrio cholerae M66-2 7774073 YP_002808848.1 CDS thiC NC_012578.1 59953 61890 D required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 59953..61890 Vibrio cholerae M66-2 7771358 YP_002808849.1 CDS thiE NC_012578.1 61894 63216 D Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 61894..63216 Vibrio cholerae M66-2 7771359 YP_002808850.1 CDS thiF NC_012578.1 63203 63979 D thiF protein 63203..63979 Vibrio cholerae M66-2 7771360 YP_002808851.1 CDS thiS NC_012578.1 63922 64179 D with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 63922..64179 Vibrio cholerae M66-2 7771361 YP_002808852.1 CDS thiG NC_012578.1 64185 64955 D functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 64185..64955 Vibrio cholerae M66-2 7771362 YP_002808853.1 CDS thiH NC_012578.1 64952 66064 D in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 64952..66064 Vibrio cholerae M66-2 7771363 YP_002808854.1 CDS VCM66_0067 NC_012578.1 66289 68082 R aminopeptidase P complement(66289..68082) Vibrio cholerae M66-2 7771364 YP_002808855.1 CDS VCM66_0068 NC_012578.1 68215 69198 R LysR family transcriptional regulator complement(68215..69198) Vibrio cholerae M66-2 7771365 YP_002808856.1 CDS VCM66_0069 NC_012578.1 69261 70463 D putative multidrug resistance protein 69261..70463 Vibrio cholerae M66-2 7771366 YP_002808857.1 CDS VCM66_0070 NC_012578.1 70567 70851 D hypothetical protein 70567..70851 Vibrio cholerae M66-2 7771367 YP_002808858.1 CDS asnC NC_012578.1 70940 71401 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(70940..71401) Vibrio cholerae M66-2 7771368 YP_002808859.1 CDS VCM66_0072 NC_012578.1 71477 73783 D GGDEF/EAL family protein 71477..73783 Vibrio cholerae M66-2 7771369 YP_002808860.1 CDS VCM66_0073 NC_012578.1 73750 74628 D hypothetical protein 73750..74628 Vibrio cholerae M66-2 7771370 YP_002808861.1 CDS VCM66_0074 NC_012578.1 74746 75135 D hypothetical protein 74746..75135 Vibrio cholerae M66-2 7771371 YP_002808862.1 CDS madN NC_012578.1 75231 76118 R MadN protein complement(75231..76118) Vibrio cholerae M66-2 7771372 YP_002808863.1 CDS uspA NC_012578.1 76175 76600 R universal stress protein A complement(76175..76600) Vibrio cholerae M66-2 7771373 YP_002808864.1 CDS VCM66_0077 NC_012578.1 76646 76741 D hypothetical protein 76646..76741 Vibrio cholerae M66-2 7771374 YP_002808865.1 CDS ftn NC_012578.1 76747 77292 D ferritin 76747..77292 Vibrio cholerae M66-2 7771375 YP_002808866.1 CDS VCM66_0079 NC_012578.1 77368 77691 D ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 77368..77691 Vibrio cholerae M66-2 7771376 YP_002808867.1 CDS VCM66_0080 NC_012578.1 77824 79020 D hypothetical protein 77824..79020 Vibrio cholerae M66-2 7771377 YP_002808868.1 CDS VCM66_0081 NC_012578.1 79017 79928 R hypothetical protein complement(79017..79928) Vibrio cholerae M66-2 7771378 YP_002808869.1 CDS VCM66_0082 NC_012578.1 80042 81583 D putative DNA recombination protein rmuC 80042..81583 Vibrio cholerae M66-2 7771379 YP_002808870.1 CDS ubiE NC_012578.1 81628 82410 D Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 81628..82410 Vibrio cholerae M66-2 7771380 YP_002808871.1 CDS VCM66_0084 NC_012578.1 82419 83042 D hypothetical protein 82419..83042 Vibrio cholerae M66-2 7771381 YP_002808872.1 CDS ubiB NC_012578.1 83039 84673 D an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; putative ubiquinone biosynthesis protein UbiB 83039..84673 Vibrio cholerae M66-2 7771382 YP_002808873.1 CDS tatA NC_012578.1 84733 84981 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 84733..84981 Vibrio cholerae M66-2 7771383 YP_002808874.1 CDS VCM66_0087 NC_012578.1 84985 85386 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 84985..85386 Vibrio cholerae M66-2 7771384 YP_002808875.1 CDS VCM66_0088 NC_012578.1 85475 86227 D Sec-independent protein translocase protein tatC 85475..86227 Vibrio cholerae M66-2 7771385 YP_002808876.1 CDS yhjA NC_012578.1 86539 87540 D cytochrome c551 peroxidase 86539..87540 Vibrio cholerae M66-2 7771386 YP_002808877.1 CDS dinF NC_012578.1 87646 89010 R DNA-damage-inducible protein F complement(87646..89010) Vibrio cholerae M66-2 7771387 YP_002808878.1 CDS VCM66_0091 NC_012578.1 89081 89950 R O-methyltransferase-like protein complement(89081..89950) Vibrio cholerae M66-2 7771388 YP_002808879.1 CDS lexA NC_012578.1 89978 90607 R Represses a number of genes involved in the response to DNA damage; LexA repressor complement(89978..90607) Vibrio cholerae M66-2 7771389 YP_002808880.1 CDS plsB NC_012578.1 90918 93353 D PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 90918..93353 Vibrio cholerae M66-2 7771390 YP_002808881.1 CDS ubiA NC_012578.1 93429 94283 R catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase complement(93429..94283) Vibrio cholerae M66-2 7771391 YP_002808882.1 CDS ubiC NC_012578.1 94284 94835 R chorismate-pyruvate lyase complement(94284..94835) Vibrio cholerae M66-2 7771392 YP_002808883.1 CDS VCM66_0096 NC_012578.1 94858 94956 R hypothetical protein complement(94858..94956) Vibrio cholerae M66-2 7771393 YP_002808884.1 CDS VCM66_0097 NC_012578.1 95027 95437 D flagellar basal body-associated protein FliL-like protein 95027..95437 Vibrio cholerae M66-2 7771394 YP_002808885.1 CDS VCM66_0098 NC_012578.1 95557 97536 R methyl-accepting chemotaxis protein complement(95557..97536) Vibrio cholerae M66-2 7771395 YP_002808886.1 CDS glpG NC_012578.1 97911 98744 R glpG protein complement(97911..98744) Vibrio cholerae M66-2 7771396 YP_002808887.1 CDS glpE NC_012578.1 98751 99071 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(98751..99071) Vibrio cholerae M66-2 7771397 YP_002808888.1 CDS VCM66_0101 NC_012578.1 99152 99367 R hypothetical protein complement(99152..99367) Vibrio cholerae M66-2 7771398 YP_002808889.1 CDS VCM66_0102 NC_012578.1 99600 99740 R hypothetical protein complement(99600..99740) Vibrio cholerae M66-2 7771399 YP_002808890.1 CDS VCM66_0103 NC_012578.1 99832 100599 R Putative deoxyribonuclease yabD complement(99832..100599) Vibrio cholerae M66-2 7771400 YP_002808891.1 CDS VCM66_0104 NC_012578.1 100655 100789 R hypothetical protein complement(100655..100789) Vibrio cholerae M66-2 7771401 YP_002808892.1 CDS hemB NC_012578.1 100776 101819 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 100776..101819 Vibrio cholerae M66-2 7771402 YP_002808893.1 CDS VCM66_0106 NC_012578.1 101923 102354 D hypothetical protein 101923..102354 Vibrio cholerae M66-2 7771403 YP_002808894.1 CDS VCM66_0107 NC_012578.1 102873 103010 R hypothetical protein complement(102873..103010) Vibrio cholerae M66-2 7771404 YP_002808895.1 CDS polI NC_012578.1 103063 105867 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 103063..105867 Vibrio cholerae M66-2 7771405 YP_002808896.1 CDS VCM66_0109 NC_012578.1 105820 105933 R hypothetical protein complement(105820..105933) Vibrio cholerae M66-2 7771406 YP_002808897.1 CDS VCM66_0110 NC_012578.1 106130 106264 D hypothetical protein 106130..106264 Vibrio cholerae M66-2 7771407 YP_002808898.1 CDS engB NC_012578.1 106614 107276 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(106614..107276) Vibrio cholerae M66-2 7771408 YP_002808899.1 CDS cycA NC_012578.1 107374 108045 D cytochrome c4 107374..108045 Vibrio cholerae M66-2 7771409 YP_002808900.1 CDS VCM66_0113 NC_012578.1 108217 108885 D methyltransferase-like protein 108217..108885 Vibrio cholerae M66-2 7771410 YP_002808901.1 CDS VCM66_0114 NC_012578.1 108885 109433 D hypothetical protein 108885..109433 Vibrio cholerae M66-2 7771411 YP_002808902.1 CDS VCM66_0115 NC_012578.1 109440 109931 D hypothetical protein 109440..109931 Vibrio cholerae M66-2 7771412 YP_002808903.1 CDS hemN NC_012578.1 110016 111458 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 110016..111458 Vibrio cholerae M66-2 7771413 YP_002808904.1 CDS hemY NC_012578.1 111522 112718 R hemY protein complement(111522..112718) Vibrio cholerae M66-2 7771414 YP_002808905.1 CDS VCM66_0118 NC_012578.1 112715 113914 R putative uroporphyrin-III C-methyltransferase complement(112715..113914) Vibrio cholerae M66-2 7771415 YP_002808906.1 CDS hemD NC_012578.1 113898 114680 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase complement(113898..114680) Vibrio cholerae M66-2 7771416 YP_002808907.1 CDS hemC NC_012578.1 114726 115679 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(114726..115679) Vibrio cholerae M66-2 7771417 YP_002808908.1 CDS VCM66_0121 NC_012578.1 115856 116002 R hypothetical protein complement(115856..116002) Vibrio cholerae M66-2 7771418 YP_002808909.1 CDS cyaA NC_012578.1 116018 118549 D catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 116018..118549 Vibrio cholerae M66-2 7771419 YP_002808910.1 CDS cyaY NC_012578.1 118655 118969 R defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein complement(118655..118969) Vibrio cholerae M66-2 7771420 YP_002808911.1 CDS lppL NC_012578.1 118946 119161 D hypothetical protein 118946..119161 Vibrio cholerae M66-2 7771421 YP_002808912.1 CDS lysA NC_012578.1 119194 120447 D diaminopimelate decarboxylase 119194..120447 Vibrio cholerae M66-2 7771422 YP_002808913.1 CDS dapF NC_012578.1 120417 121289 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 120417..121289 Vibrio cholerae M66-2 7771423 YP_002808914.1 CDS VCM66_0127 NC_012578.1 121303 122001 D hypothetical protein 121303..122001 Vibrio cholerae M66-2 7771424 YP_002808915.1 CDS xerC NC_012578.1 121970 122905 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 121970..122905 Vibrio cholerae M66-2 7771425 YP_002808916.1 CDS VCM66_0129 NC_012578.1 122908 123627 D hypothetical protein 122908..123627 Vibrio cholerae M66-2 7771426 YP_002808917.1 CDS VCM66_0130 NC_012578.1 123737 126226 D GGDEF/EAL family protein 123737..126226 Vibrio cholerae M66-2 7771427 YP_002808918.1 CDS VCM66_0131 NC_012578.1 126259 126855 R hypothetical protein complement(126259..126855) Vibrio cholerae M66-2 7771428 YP_002808919.1 CDS VCM66_0132 NC_012578.1 126852 128396 R hypothetical protein complement(126852..128396) Vibrio cholerae M66-2 7771429 YP_002808920.1 CDS VCM66_0133 NC_012578.1 128409 128597 D hypothetical protein 128409..128597 Vibrio cholerae M66-2 7771430 YP_002808921.1 CDS VCM66_0134 NC_012578.1 128680 129507 R hypothetical protein complement(128680..129507) Vibrio cholerae M66-2 7771431 YP_002808922.1 CDS lypA NC_012578.1 129622 130638 R lysophospholipase L2 complement(129622..130638) Vibrio cholerae M66-2 7771432 YP_002808923.1 CDS rhtB NC_012578.1 130713 131330 D homoserine/homoserine lactone efflux protein 130713..131330 Vibrio cholerae M66-2 7771433 YP_002808924.1 CDS VCM66_0137 NC_012578.1 131278 132576 D HD-GYP/EAL family protein 131278..132576 Vibrio cholerae M66-2 7771434 YP_002808925.1 CDS VCM66_0138 NC_012578.1 132584 132703 R hypothetical protein complement(132584..132703) Vibrio cholerae M66-2 7771435 YP_002808926.1 CDS VCM66_0139 NC_012578.1 132756 133226 R DPS family protein complement(132756..133226) Vibrio cholerae M66-2 7771436 YP_002808927.1 CDS VCM66_0140 NC_012578.1 133396 133725 R hypothetical protein complement(133396..133725) Vibrio cholerae M66-2 7771437 YP_002808928.1 CDS VCM66_0141 NC_012578.1 133764 133868 D hypothetical protein 133764..133868 Vibrio cholerae M66-2 7771438 YP_002808929.1 CDS VCM66_0142 NC_012578.1 133930 134298 D hypothetical protein 133930..134298 Vibrio cholerae M66-2 7771439 YP_002808930.1 CDS VCM66_0144 NC_012578.1 135175 135804 D hypothetical protein 135175..135804 Vibrio cholerae M66-2 7771440 YP_002808931.1 CDS VCM66_0145 NC_012578.1 135853 136119 R hypothetical protein complement(135853..136119) Vibrio cholerae M66-2 7771441 YP_002808932.1 CDS VCM66_0146 NC_012578.1 136116 136715 R Putative methylase complement(136116..136715) Vibrio cholerae M66-2 7771442 YP_002808933.1 CDS ftsY NC_012578.1 136919 138100 D cell division protein FtsY 136919..138100 Vibrio cholerae M66-2 7771443 YP_002808934.1 CDS ftsE NC_012578.1 138122 138823 D cell division ATP-binding protein FtsE 138122..138823 Vibrio cholerae M66-2 7771444 YP_002808935.1 CDS ftsX NC_012578.1 138813 139805 D cell division protein FtsX 138813..139805 Vibrio cholerae M66-2 7771445 YP_002808936.1 CDS rpoH NC_012578.1 139975 140835 D binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 139975..140835 Vibrio cholerae M66-2 7771446 YP_002808937.1 CDS dude NC_012578.1 141037 142437 R catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase complement(141037..142437) Vibrio cholerae M66-2 7771447 YP_002808938.1 CDS VCM66_0152 NC_012578.1 142745 143386 D negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 142745..143386 Vibrio cholerae M66-2 7771448 YP_002808939.1 CDS VCM66_0153 NC_012578.1 143426 143797 D hypothetical protein 143426..143797 Vibrio cholerae M66-2 7771449 YP_002808940.1 CDS trmA NC_012578.1 143834 144943 R catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase complement(143834..144943) Vibrio cholerae M66-2 7771450 YP_002808941.1 CDS btuB NC_012578.1 145341 147176 D vitamin B12 receptor 145341..147176 Vibrio cholerae M66-2 7771451 YP_002808942.1 CDS VCM66_0156 NC_012578.1 147249 148856 R alkaline serine protease complement(147249..148856) Vibrio cholerae M66-2 7771452 YP_002808943.1 CDS murI NC_012578.1 149249 150046 D converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 149249..150046 Vibrio cholerae M66-2 7771453 YP_002808944.1 CDS VCM66_0158 NC_012578.1 150012 150470 R RNA-binding protein complement(150012..150470) Vibrio cholerae M66-2 7771454 YP_002808945.1 CDS ilvY NC_012578.1 156659 157555 R participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY complement(156659..157555) Vibrio cholerae M66-2 7774062 YP_002808946.1 CDS ilvC NC_012578.1 157693 159177 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 157693..159177 Vibrio cholerae M66-2 7771456 YP_002808947.1 CDS VCM66_0162 NC_012578.1 159304 159555 R hypothetical protein complement(159304..159555) Vibrio cholerae M66-2 7771457 YP_002808948.1 CDS VCM66_0163 NC_012578.1 159671 162781 R putative multidrug resistance protein complement(159671..162781) Vibrio cholerae M66-2 7771458 YP_002808949.1 CDS VCM66_0164 NC_012578.1 162793 163899 R hypothetical protein complement(162793..163899) Vibrio cholerae M66-2 7771459 YP_002808950.1 CDS VCM66_0165 NC_012578.1 163918 164514 R TetR family transcriptional regulator complement(163918..164514) Vibrio cholerae M66-2 7771460 YP_002808951.1 CDS rep NC_012578.1 164660 166675 D ATP-dependent DNA helicase Rep 164660..166675 Vibrio cholerae M66-2 7771461 YP_002808952.1 CDS cycB NC_012578.1 166742 167149 R cytochrome c5 complement(166742..167149) Vibrio cholerae M66-2 7771462 YP_002808953.1 CDS VCM66_0168 NC_012578.1 168484 168651 R hypothetical protein complement(168484..168651) Vibrio cholerae M66-2 7774059 YP_002808954.1 CDS VCM66_0169 NC_012578.1 168784 170499 D peptide ABC transporter ATP-binding protein 168784..170499 Vibrio cholerae M66-2 7771464 YP_002808955.1 CDS VCM66_0170 NC_012578.1 170519 172147 D peptide ABC transporter substrate-binding protein 170519..172147 Vibrio cholerae M66-2 7771465 YP_002808956.1 CDS VCM66_0171 NC_012578.1 172251 173279 D peptide ABC transporter permease 172251..173279 Vibrio cholerae M66-2 7771466 YP_002808957.1 CDS VCM66_0172 NC_012578.1 173282 174220 D peptide ABC transporter permease 173282..174220 Vibrio cholerae M66-2 7771467 YP_002808958.1 CDS VCM66_0173 NC_012578.1 174395 175342 D hypothetical protein 174395..175342 Vibrio cholerae M66-2 7771468 YP_002808959.1 CDS gor NC_012578.1 175437 176804 R catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase complement(175437..176804) Vibrio cholerae M66-2 7771469 YP_002808960.1 CDS VCM66_0175 NC_012578.1 176898 177737 R hypothetical protein complement(176898..177737) Vibrio cholerae M66-2 7771470 YP_002808961.1 CDS prlC NC_012578.1 178017 180059 D oligopeptidase A 178017..180059 Vibrio cholerae M66-2 7771471 YP_002808962.1 CDS VCM66_0177 NC_012578.1 180084 180182 D hypothetical protein 180084..180182 Vibrio cholerae M66-2 7771472 YP_002808963.1 CDS uvrD NC_012578.1 180197 182368 D unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 180197..182368 Vibrio cholerae M66-2 7771473 YP_002808964.1 CDS VCM66_0179 NC_012578.1 183114 183782 R Threonine efflux protein complement(183114..183782) Vibrio cholerae M66-2 7771474 YP_002808965.1 CDS VCM66_0180 NC_012578.1 183857 184669 R AraC family transcriptional regulator complement(183857..184669) Vibrio cholerae M66-2 7771475 YP_002808966.1 CDS VCM66_0181 NC_012578.1 184706 184801 R hypothetical protein complement(184706..184801) Vibrio cholerae M66-2 7771476 YP_002808967.1 CDS rarD NC_012578.1 186753 187661 R rarD protein complement(186753..187661) Vibrio cholerae M66-2 7773949 YP_002808968.1 CDS recQ NC_012578.1 187795 189657 D functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 187795..189657 Vibrio cholerae M66-2 7771478 YP_002808969.1 CDS VCM66_0185 NC_012578.1 189650 189949 D gene 3 protein-like protein 189650..189949 Vibrio cholerae M66-2 7771479 YP_002808970.1 CDS VCM66_0186 NC_012578.1 190105 190482 D hypothetical protein 190105..190482 Vibrio cholerae M66-2 7771480 YP_002808971.1 CDS VCM66_0187 NC_012578.1 190518 192353 R putative hemolysin secretion ATP-binding protein complement(190518..192353) Vibrio cholerae M66-2 7771481 YP_002808972.1 CDS fhuA NC_012578.1 192425 194581 D iron(III) compound receptor 192425..194581 Vibrio cholerae M66-2 7771482 YP_002808973.1 CDS fhuB NC_012578.1 194640 195497 D iron(III) ABC transporter ATP-binding protein 194640..195497 Vibrio cholerae M66-2 7771483 YP_002808974.1 CDS fhuC NC_012578.1 195488 196447 D iron(III) ABC transporter periplasmic iron-compound-binding protein 195488..196447 Vibrio cholerae M66-2 7771484 YP_002808975.1 CDS fhuD NC_012578.1 196444 198405 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 196444..198405 Vibrio cholerae M66-2 7771485 YP_002808976.1 CDS VCM66_0192 NC_012578.1 198432 199280 R Putative HTH-type transcriptional regulator yfeT complement(198432..199280) Vibrio cholerae M66-2 7771486 YP_002808977.1 CDS VCM66_0193 NC_012578.1 199323 199514 D hypothetical protein 199323..199514 Vibrio cholerae M66-2 7771487 YP_002808978.1 CDS murQ NC_012578.1 199496 200413 D catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 199496..200413 Vibrio cholerae M66-2 7771488 YP_002808979.1 CDS murP NC_012578.1 200434 201882 D belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunits EIIBC 200434..201882 Vibrio cholerae M66-2 7771489 YP_002808980.1 CDS VCM66_0196 NC_012578.1 201989 202477 R hypothetical protein complement(201989..202477) Vibrio cholerae M66-2 7771490 YP_002808981.1 CDS VCM66_0197 NC_012578.1 202543 203409 R hypothetical protein complement(202543..203409) Vibrio cholerae M66-2 7771491 YP_002808982.1 CDS rph NC_012578.1 203516 204289 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 203516..204289 Vibrio cholerae M66-2 7771492 YP_002808983.1 CDS pyrE NC_012578.1 204652 205296 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 204652..205296 Vibrio cholerae M66-2 7771493 YP_002808984.1 CDS htrB NC_012578.1 206375 207331 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(206375..207331) Vibrio cholerae M66-2 7773950 YP_002808985.1 CDS slmA NC_012578.1 207328 207960 R FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein complement(207328..207960) Vibrio cholerae M66-2 7771495 YP_002808986.1 CDS dfp NC_012578.1 208077 209276 R catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(208077..209276) Vibrio cholerae M66-2 7771496 YP_002808987.1 CDS VCM66_0204 NC_012578.1 209444 211138 D methyl-accepting chemotaxis protein 209444..211138 Vibrio cholerae M66-2 7771497 YP_002808988.1 CDS radC NC_012578.1 211250 211924 D Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 211250..211924 Vibrio cholerae M66-2 7771498 YP_002808989.1 CDS rpmB NC_012578.1 212219 212455 D required for 70S ribosome assembly; 50S ribosomal protein L28 212219..212455 Vibrio cholerae M66-2 7771499 YP_002808990.1 CDS rpmG NC_012578.1 212469 212636 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 212469..212636 Vibrio cholerae M66-2 7771500 YP_002808991.1 CDS VCM66_0208 NC_012578.1 212857 213345 D hypothetical protein 212857..213345 Vibrio cholerae M66-2 7771501 YP_002808992.1 CDS mutM NC_012578.1 213355 214164 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 213355..214164 Vibrio cholerae M66-2 7771502 YP_002808993.1 CDS coaD NC_012578.1 214261 214755 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(214261..214755) Vibrio cholerae M66-2 7771503 YP_002808994.1 CDS VCM66_0211 NC_012578.1 214866 215903 D putative ADP-heptose--LPS heptosyltransferase II 214866..215903 Vibrio cholerae M66-2 7771504 YP_002808995.1 CDS VCM66_0212 NC_012578.1 215965 216744 R putative lipopolysaccharide biosynthesis glycosyltransferase complement(215965..216744) Vibrio cholerae M66-2 7771505 YP_002808996.1 CDS VCM66_0213 NC_012578.1 216787 217860 R putative lipopolysaccharide biosynthesis protein complement(216787..217860) Vibrio cholerae M66-2 7771506 YP_002808997.1 CDS VCM66_0214 NC_012578.1 217863 217958 R hypothetical protein complement(217863..217958) Vibrio cholerae M66-2 7771507 YP_002808998.1 CDS VCM66_0215 NC_012578.1 217940 218695 D catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position; 3-deoxy-D-manno-octulosonic-acid kinase 217940..218695 Vibrio cholerae M66-2 7771508 YP_002808999.1 CDS VCM66_0216 NC_012578.1 218699 219658 D hypothetical protein 218699..219658 Vibrio cholerae M66-2 7771509 YP_002809000.1 CDS VCM66_0217 NC_012578.1 219662 220591 R hypothetical protein complement(219662..220591) Vibrio cholerae M66-2 7771510 YP_002809001.1 CDS VCM66_0218 NC_012578.1 220588 221331 R hypothetical protein complement(220588..221331) Vibrio cholerae M66-2 7771511 YP_002809002.1 CDS VCM66_0219 NC_012578.1 221328 222911 R hypothetical protein complement(221328..222911) Vibrio cholerae M66-2 7771512 YP_002809003.1 CDS VCM66_0220 NC_012578.1 222902 223282 R hypothetical protein complement(222902..223282) Vibrio cholerae M66-2 7771513 YP_002809004.1 CDS kdtA NC_012578.1 223279 224598 R catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase complement(223279..224598) Vibrio cholerae M66-2 7771514 YP_002809005.1 CDS VCM66_0222 NC_012578.1 224559 225347 R hypothetical protein complement(224559..225347) Vibrio cholerae M66-2 7771515 YP_002809006.1 CDS VCM66_0223 NC_012578.1 225344 226393 R putative lipopolysaccharide biosynthesis protein complement(225344..226393) Vibrio cholerae M66-2 7771516 YP_002809007.1 CDS rfaF NC_012578.1 226390 227430 R ADP-heptose--LPS heptosyltransferase II complement(226390..227430) Vibrio cholerae M66-2 7771517 YP_002809008.1 CDS VCM66_0225 NC_012578.1 227427 228626 R hypothetical protein complement(227427..228626) Vibrio cholerae M66-2 7771518 YP_002809009.1 CDS VCM66_0226 NC_012578.1 228628 229194 R transferase, hexapeptide repeat family complement(228628..229194) Vibrio cholerae M66-2 7771519 YP_002809010.1 CDS rfaD NC_012578.1 231131 232075 R catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-mannoheptose-6-epimerase complement(231131..232075) Vibrio cholerae M66-2 7773951 YP_002809011.1 CDS rfbA NC_012578.1 232517 233914 D mannose-1-phosphate guanylyltransferase 232517..233914 Vibrio cholerae M66-2 7771521 YP_002809012.1 CDS rfbB NC_012578.1 233917 235308 D phosphomannomutase 233917..235308 Vibrio cholerae M66-2 7771522 YP_002809013.1 CDS rfbD NC_012578.1 235311 236432 D GDP-mannose 4,6-dehydratase 235311..236432 Vibrio cholerae M66-2 7771523 YP_002809014.1 CDS rfbE NC_012578.1 236443 237546 D perosamine synthase 236443..237546 Vibrio cholerae M66-2 7771524 YP_002809015.1 CDS rfbG NC_012578.1 237543 238934 D rfbG protein 237543..238934 Vibrio cholerae M66-2 7771525 YP_002809016.1 CDS rfbH NC_012578.1 238906 239700 D lipopolysaccharide/O-antigen transport protein 238906..239700 Vibrio cholerae M66-2 7771526 YP_002809017.1 CDS rfbI NC_012578.1 239639 240454 D lipopolysaccharide/O-antigen transport protein 239639..240454 Vibrio cholerae M66-2 7771527 YP_002809018.1 CDS VCM66_0236 NC_012578.1 240493 240735 D putative acyl carrier protein 240493..240735 Vibrio cholerae M66-2 7771528 YP_002809019.1 CDS rfbL NC_012578.1 240741 242156 D rfbL protein 240741..242156 Vibrio cholerae M66-2 7771529 YP_002809020.1 CDS VCM66_0238 NC_012578.1 242165 243289 D putative iron-containing alcohol dehydrogenase 242165..243289 Vibrio cholerae M66-2 7771530 YP_002809021.1 CDS VCM66_0239 NC_012578.1 243280 245757 D acyl protein synthase/acyl-CoA reductase 243280..245757 Vibrio cholerae M66-2 7771531 YP_002809022.1 CDS VCM66_0240 NC_012578.1 245827 246393 D acetyltransferase RfbO 245827..246393 Vibrio cholerae M66-2 7771532 YP_002809023.1 CDS VCM66_0241 NC_012578.1 246543 246623 D IS1004 transposase 246543..246623 Vibrio cholerae M66-2 7771533 YP_002809024.1 CDS VCM66_0243 NC_012578.1 248086 248946 D rfbT-like protein 248086..248946 Vibrio cholerae M66-2 7773952 YP_002809025.1 CDS rfbV NC_012578.1 248981 250213 R lipopolysaccharide biosynthesis protein RfbV complement(248981..250213) Vibrio cholerae M66-2 7771535 YP_002809026.1 CDS rfbU NC_012578.1 250101 251966 R mannosyl-transferase complement(250101..251966) Vibrio cholerae M66-2 7771536 YP_002809027.1 CDS VCM66_0246 NC_012578.1 252027 252167 R hypothetical protein complement(252027..252167) Vibrio cholerae M66-2 7771537 YP_002809028.1 CDS galE-1 NC_012578.1 252119 253090 D UDP-glucose 4-epimerase 252119..253090 Vibrio cholerae M66-2 7771538 YP_002809029.1 CDS VCM66_0248 NC_012578.1 253098 253652 D putative galactosyl-transferase 253098..253652 Vibrio cholerae M66-2 7771539 YP_002809030.1 CDS VCM66_0249 NC_012578.1 253795 255162 D hypothetical protein 253795..255162 Vibrio cholerae M66-2 7771540 YP_002809031.1 CDS VCM66_0250 NC_012578.1 255424 256662 R hypothetical protein complement(255424..256662) Vibrio cholerae M66-2 7771541 YP_002809032.1 CDS VCM66_0251 NC_012578.1 256717 257289 R hypothetical protein complement(256717..257289) Vibrio cholerae M66-2 7771542 YP_002809033.1 CDS VCM66_0252 NC_012578.1 257289 258212 R D-isomer specific 2-hydroxyacid dehydrogenase family protein complement(257289..258212) Vibrio cholerae M66-2 7771543 YP_002809034.1 CDS VCM66_0253 NC_012578.1 258205 258873 D hypothetical protein 258205..258873 Vibrio cholerae M66-2 7771544 YP_002809035.1 CDS manA-1 NC_012578.1 259236 260435 D mannose-6-phosphate isomerase 259236..260435 Vibrio cholerae M66-2 7771545 YP_002809036.1 CDS VCM66_0255 NC_012578.1 260401 261381 D ROK family protein 260401..261381 Vibrio cholerae M66-2 7771546 YP_002809037.1 CDS VCM66_0256 NC_012578.1 261729 262787 R hypothetical protein complement(261729..262787) Vibrio cholerae M66-2 7771547 YP_002809038.1 CDS hupA NC_012578.1 263159 263431 D DNA-binding protein HU 263159..263431 Vibrio cholerae M66-2 7771548 YP_002809039.1 CDS VCM66_0259 NC_012578.1 263432 264166 D hypothetical protein 263432..264166 Vibrio cholerae M66-2 7771549 YP_002809040.1 CDS purD NC_012578.1 264266 265555 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(264266..265555) Vibrio cholerae M66-2 7771550 YP_002809041.1 CDS purH NC_012578.1 265614 267206 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(265614..267206) Vibrio cholerae M66-2 7771551 YP_002809042.1 CDS zntR NC_012578.1 267492 267893 D mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 267492..267893 Vibrio cholerae M66-2 7771552 YP_002809043.1 CDS VCM66_0263 NC_012578.1 268054 269679 D regulates the cadBA operon; DNA-binding transcriptional activator CadC 268054..269679 Vibrio cholerae M66-2 7771553 YP_002809044.1 CDS VCM66_0264 NC_012578.1 270102 270230 D hypothetical protein 270102..270230 Vibrio cholerae M66-2 7771554 YP_002809045.1 CDS cadB NC_012578.1 270379 271716 D antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 270379..271716 Vibrio cholerae M66-2 7771555 YP_002809046.1 CDS cadA NC_012578.1 271760 273961 D lysine decarboxylase 271760..273961 Vibrio cholerae M66-2 7771556 YP_002809047.1 CDS VCM66_0267 NC_012578.1 274079 275749 R methyl-accepting chemotaxis protein complement(274079..275749) Vibrio cholerae M66-2 7771557 YP_002809048.1 CDS VCM66_0268 NC_012578.1 275984 276661 R hypothetical protein complement(275984..276661) Vibrio cholerae M66-2 7771558 YP_002809049.1 CDS VCM66_0269 NC_012578.1 276682 278724 R TonB system receptor complement(276682..278724) Vibrio cholerae M66-2 7771559 YP_002809050.1 CDS eda NC_012578.1 278947 279552 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(278947..279552) Vibrio cholerae M66-2 7771560 YP_002809051.1 CDS VCM66_0271 NC_012578.1 279565 280941 R putative gluconate permease complement(279565..280941) Vibrio cholerae M66-2 7771561 YP_002809052.1 CDS gntV NC_012578.1 281095 281610 D thermoresistant gluconokinase 281095..281610 Vibrio cholerae M66-2 7771562 YP_002809053.1 CDS edd NC_012578.1 281547 283403 D catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 281547..283403 Vibrio cholerae M66-2 7771563 YP_002809054.1 CDS gntR NC_012578.1 283479 284477 R gluconate utilization system gnt-I transcriptional repressor complement(283479..284477) Vibrio cholerae M66-2 7771564 YP_002809055.1 CDS fis NC_012578.1 284615 284911 R Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis complement(284615..284911) Vibrio cholerae M66-2 7771565 YP_002809056.1 CDS VCM66_0276 NC_012578.1 284935 285930 R NifR3/Smm1 family protein complement(284935..285930) Vibrio cholerae M66-2 7771566 YP_002809057.1 CDS VCM66_0277 NC_012578.1 285911 286003 R hypothetical protein complement(285911..286003) Vibrio cholerae M66-2 7771567 YP_002809058.1 CDS prmA NC_012578.1 286043 286930 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase complement(286043..286930) Vibrio cholerae M66-2 7771568 YP_002809059.1 CDS VCM66_0279 NC_012578.1 286911 287027 R hypothetical protein complement(286911..287027) Vibrio cholerae M66-2 7771569 YP_002809060.1 CDS accC NC_012578.1 287139 288482 R an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit complement(287139..288482) Vibrio cholerae M66-2 7771570 YP_002809061.1 CDS accB NC_012578.1 288497 289087 R composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit complement(288497..289087) Vibrio cholerae M66-2 7771571 YP_002809062.1 CDS aroQ NC_012578.1 289015 289467 R catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase complement(289015..289467) Vibrio cholerae M66-2 7771572 YP_002809063.1 CDS acs-1 NC_012578.1 289847 291847 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase complement(289847..291847) Vibrio cholerae M66-2 7771573 YP_002809064.1 CDS VCM66_0284 NC_012578.1 291999 292670 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(291999..292670) Vibrio cholerae M66-2 7771574 YP_002809065.1 CDS VCM66_0285 NC_012578.1 292637 294460 R hypothetical protein complement(292637..294460) Vibrio cholerae M66-2 7771575 YP_002809066.1 CDS VCM66_0286 NC_012578.1 294415 294621 R hypothetical protein complement(294415..294621) Vibrio cholerae M66-2 7771576 YP_002809067.1 CDS VCM66_0287 NC_012578.1 294720 295910 D putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; putative 3-phenylpropionic acid transporter 294720..295910 Vibrio cholerae M66-2 7771577 YP_002809068.1 CDS VCM66_0288 NC_012578.1 296003 299446 D sensor histidine kinase 296003..299446 Vibrio cholerae M66-2 7771578 YP_002809069.1 CDS gppA NC_012578.1 299569 301062 R catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase complement(299569..301062) Vibrio cholerae M66-2 7771579 YP_002809070.1 CDS rhlB NC_012578.1 301070 302386 R enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB complement(301070..302386) Vibrio cholerae M66-2 7771580 YP_002809071.1 CDS trxA NC_012578.1 302498 302824 D thioredoxin 302498..302824 Vibrio cholerae M66-2 7771581 YP_002809072.1 CDS rho NC_012578.1 303022 304281 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 303022..304281 Vibrio cholerae M66-2 7771582 YP_002809073.1 CDS VCM66_0293 NC_012578.1 304380 305372 D hypothetical protein 304380..305372 Vibrio cholerae M66-2 7771583 YP_002809074.1 CDS VCM66_0294 NC_012578.1 305454 307295 D 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 305454..307295 Vibrio cholerae M66-2 7771584 YP_002809075.1 CDS VCM66_0295 NC_012578.1 307292 307561 D ferredoxin 307292..307561 Vibrio cholerae M66-2 7771585 YP_002809076.1 CDS fre NC_012578.1 307577 308287 D NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 307577..308287 Vibrio cholerae M66-2 7771586 YP_002809077.1 CDS VCM66_0297 NC_012578.1 308447 308542 D hypothetical protein 308447..308542 Vibrio cholerae M66-2 7771587 YP_002809078.1 CDS pssA NC_012578.1 314437 315777 R catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase complement(314437..315777) Vibrio cholerae M66-2 7774008 YP_002809079.1 CDS VCM66_0300 NC_012578.1 315748 315900 D hypothetical protein 315748..315900 Vibrio cholerae M66-2 7771589 YP_002809080.1 CDS VCM66_0301 NC_012578.1 315872 316318 R hypothetical protein complement(315872..316318) Vibrio cholerae M66-2 7771590 YP_002809081.1 CDS murB NC_012578.1 316331 317404 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 316331..317404 Vibrio cholerae M66-2 7771591 YP_002809082.1 CDS birA NC_012578.1 317401 318363 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 317401..318363 Vibrio cholerae M66-2 7771592 YP_002809083.1 CDS coaA NC_012578.1 318413 319540 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(318413..319540) Vibrio cholerae M66-2 7771593 YP_002809084.1 CDS tufB NC_012578.1 320052 321236 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 320052..321236 Vibrio cholerae M66-2 7774068 YP_002809085.1 CDS secE NC_012578.1 321445 321840 D forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 321445..321840 Vibrio cholerae M66-2 7771595 YP_002809086.1 CDS nusG NC_012578.1 321856 322404 D Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 321856..322404 Vibrio cholerae M66-2 7771596 YP_002809087.1 CDS rplK NC_012578.1 322535 322963 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 322535..322963 Vibrio cholerae M66-2 7771597 YP_002809088.1 CDS rplA NC_012578.1 322968 323669 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 322968..323669 Vibrio cholerae M66-2 7771598 YP_002809089.1 CDS rplJ NC_012578.1 323939 324427 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 323939..324427 Vibrio cholerae M66-2 7771599 YP_002809090.1 CDS rplL NC_012578.1 324494 324859 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 324494..324859 Vibrio cholerae M66-2 7771600 YP_002809091.1 CDS rpoB NC_012578.1 324998 329125 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 324998..329125 Vibrio cholerae M66-2 7771601 YP_002809092.1 CDS rpoC NC_012578.1 329230 333435 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 329230..333435 Vibrio cholerae M66-2 7771602 YP_002809093.1 CDS rsd NC_012578.1 333546 334040 R binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor complement(333546..334040) Vibrio cholerae M66-2 7771603 YP_002809094.1 CDS nudC NC_012578.1 334185 334994 D can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 334185..334994 Vibrio cholerae M66-2 7771604 YP_002809095.1 CDS hemE NC_012578.1 335237 336316 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 335237..336316 Vibrio cholerae M66-2 7771605 YP_002809096.1 CDS VCM66_0317 NC_012578.1 336322 337050 D TetR family transcriptional regulator 336322..337050 Vibrio cholerae M66-2 7771606 YP_002809097.1 CDS VCM66_0318 NC_012578.1 337137 338096 D hypothetical protein 337137..338096 Vibrio cholerae M66-2 7771607 YP_002809098.1 CDS VCM66_0319 NC_012578.1 338093 339241 R NlpD-like protein complement(338093..339241) Vibrio cholerae M66-2 7771608 YP_002809099.1 CDS yibO NC_012578.1 339410 340942 R catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase complement(339410..340942) Vibrio cholerae M66-2 7771609 YP_002809100.1 CDS VCM66_0321 NC_012578.1 341085 342026 R hypothetical protein complement(341085..342026) Vibrio cholerae M66-2 7771610 YP_002809101.1 CDS VCM66_0322 NC_012578.1 342124 343560 R putative transporter complement(342124..343560) Vibrio cholerae M66-2 7771611 YP_002809102.1 CDS psd NC_012578.1 343747 344604 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(343747..344604) Vibrio cholerae M66-2 7771612 YP_002809103.1 CDS rsgA NC_012578.1 344700 345761 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(344700..345761) Vibrio cholerae M66-2 7771613 YP_002809104.1 CDS orn NC_012578.1 345884 346429 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 345884..346429 Vibrio cholerae M66-2 7771614 YP_002809105.1 CDS VCM66_0326 NC_012578.1 348302 349411 R iron-sulfur cluster-binding protein complement(348302..349411) Vibrio cholerae M66-2 7774049 YP_002809106.1 CDS VCM66_0327 NC_012578.1 349514 350080 D hypothetical protein 349514..350080 Vibrio cholerae M66-2 7771616 YP_002809107.1 CDS amiB NC_012578.1 350047 351792 D N-acetylmuramoyl-L-alanine amidase 350047..351792 Vibrio cholerae M66-2 7771617 YP_002809108.1 CDS mutL NC_012578.1 351799 353760 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 351799..353760 Vibrio cholerae M66-2 7771618 YP_002809109.1 CDS miaA NC_012578.1 353757 354704 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 353757..354704 Vibrio cholerae M66-2 7771619 YP_002809110.1 CDS hfq NC_012578.1 354876 355139 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 354876..355139 Vibrio cholerae M66-2 7771620 YP_002809111.1 CDS hflX NC_012578.1 355172 356461 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; putative GTPase HflX 355172..356461 Vibrio cholerae M66-2 7771621 YP_002809112.1 CDS hflK NC_012578.1 356507 357694 D hflK protein 356507..357694 Vibrio cholerae M66-2 7771622 YP_002809113.1 CDS hflC NC_012578.1 357697 358677 D hflC protein 357697..358677 Vibrio cholerae M66-2 7771623 YP_002809114.1 CDS VCM66_0335 NC_012578.1 358720 358926 D hypothetical protein 358720..358926 Vibrio cholerae M66-2 7771624 YP_002809115.1 CDS slyX NC_012578.1 358967 359185 R hypothetical protein complement(358967..359185) Vibrio cholerae M66-2 7771625 YP_002809116.1 CDS VCM66_0337 NC_012578.1 359197 360180 R hypothetical protein complement(359197..360180) Vibrio cholerae M66-2 7771626 YP_002809117.1 CDS fkpA NC_012578.1 360317 361096 D FKBP-type peptidyl-prolyl cis-trans isomerase 360317..361096 Vibrio cholerae M66-2 7771627 YP_002809118.1 CDS VCM66_0339 NC_012578.1 361295 362017 D hypothetical protein 361295..362017 Vibrio cholerae M66-2 7771628 YP_002809119.1 CDS VCM66_0340 NC_012578.1 362014 362409 D in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 362014..362409 Vibrio cholerae M66-2 7771629 YP_002809120.1 CDS VCM66_0341 NC_012578.1 362406 362762 D hypothetical protein 362406..362762 Vibrio cholerae M66-2 7771630 YP_002809121.1 CDS VCM66_0342 NC_012578.1 362772 363047 D hypothetical protein 362772..363047 Vibrio cholerae M66-2 7771631 YP_002809122.1 CDS rpsL NC_012578.1 363232 363606 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 363232..363606 Vibrio cholerae M66-2 7771632 YP_002809123.1 CDS rpsG NC_012578.1 363722 364192 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 363722..364192 Vibrio cholerae M66-2 7771633 YP_002809124.1 CDS fusA-1 NC_012578.1 364268 366364 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 364268..366364 Vibrio cholerae M66-2 7771634 YP_002809125.1 CDS tufA NC_012578.1 366487 367671 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 366487..367671 Vibrio cholerae M66-2 7771635 YP_002809126.1 CDS VCM66_0347 NC_012578.1 367792 367902 R hypothetical protein complement(367792..367902) Vibrio cholerae M66-2 7771636 YP_002809127.1 CDS bfd NC_012578.1 367974 368162 D bacterioferritin-associated ferredoxin 367974..368162 Vibrio cholerae M66-2 7771637 YP_002809128.1 CDS bfr NC_012578.1 368232 368708 D bacterioferritin 368232..368708 Vibrio cholerae M66-2 7771638 YP_002809129.1 CDS rpsF NC_012578.1 368920 369288 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 368920..369288 Vibrio cholerae M66-2 7771639 YP_002809130.1 CDS priB NC_012578.1 369296 369598 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 369296..369598 Vibrio cholerae M66-2 7771640 YP_002809131.1 CDS rpsR NC_012578.1 369614 369841 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 369614..369841 Vibrio cholerae M66-2 7771641 YP_002809132.1 CDS rplI NC_012578.1 369875 370324 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 369875..370324 Vibrio cholerae M66-2 7771642 YP_002809133.1 CDS VCM66_0354 NC_012578.1 370386 371195 R hypothetical protein complement(370386..371195) Vibrio cholerae M66-2 7771643 YP_002809134.1 CDS dnaB NC_012578.1 371321 372727 D unwinds double stranded DNA; replicative DNA helicase 371321..372727 Vibrio cholerae M66-2 7771644 YP_002809135.1 CDS alr NC_012578.1 372699 373826 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 372699..373826 Vibrio cholerae M66-2 7771645 YP_002809136.1 CDS VCM66_0357 NC_012578.1 373909 374328 R hypothetical protein complement(373909..374328) Vibrio cholerae M66-2 7771646 YP_002809137.1 CDS pgi NC_012578.1 374613 376265 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 374613..376265 Vibrio cholerae M66-2 7771647 YP_002809138.1 CDS VCM66_0359 NC_012578.1 376298 376405 R hypothetical protein complement(376298..376405) Vibrio cholerae M66-2 7771648 YP_002809139.1 CDS VCM66_0360 NC_012578.1 376468 377646 D hypothetical protein 376468..377646 Vibrio cholerae M66-2 7771649 YP_002809140.1 CDS VCM66_0361 NC_012578.1 377763 378224 R hypothetical protein complement(377763..378224) Vibrio cholerae M66-2 7771650 YP_002809141.1 CDS VCM66_0362 NC_012578.1 378234 378701 R putative zinc uptake regulation protein complement(378234..378701) Vibrio cholerae M66-2 7771651 YP_002809142.1 CDS VCM66_0363 NC_012578.1 379056 380039 D tRNA-dihydrouridine synthase A 379056..380039 Vibrio cholerae M66-2 7771652 YP_002809143.1 CDS pspG NC_012578.1 380200 380412 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 380200..380412 Vibrio cholerae M66-2 7771653 YP_002809144.1 CDS VCM66_0366 NC_012578.1 380501 381166 D hypothetical protein 380501..381166 Vibrio cholerae M66-2 7771654 YP_002809145.1 CDS VCM66_0367 NC_012578.1 381120 381290 D hypothetical protein 381120..381290 Vibrio cholerae M66-2 7771655 YP_002809146.1 CDS VCM66_0368 NC_012578.1 381248 381517 D hypothetical protein 381248..381517 Vibrio cholerae M66-2 7771656 YP_002809147.1 CDS cysJ NC_012578.1 381603 383447 D sulfite reductase (NADPH) flavoprotein alpha-component 381603..383447 Vibrio cholerae M66-2 7771657 YP_002809148.1 CDS cysI NC_012578.1 383447 385180 D hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 383447..385180 Vibrio cholerae M66-2 7771658 YP_002809149.1 CDS cysH NC_012578.1 385173 385934 D catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 385173..385934 Vibrio cholerae M66-2 7771659 YP_002809150.1 CDS VCM66_0372 NC_012578.1 386071 386166 D hypothetical protein 386071..386166 Vibrio cholerae M66-2 7771660 YP_002809151.1 CDS VCM66_0374 NC_012578.1 392233 393567 R putative Na+/H+ antiporter complement(392233..393567) Vibrio cholerae M66-2 7774009 YP_002809152.1 CDS metH NC_012578.1 393764 397444 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 393764..397444 Vibrio cholerae M66-2 7771662 YP_002809153.1 CDS lysC NC_012578.1 397517 398956 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III complement(397517..398956) Vibrio cholerae M66-2 7771663 YP_002809154.1 CDS VCM66_0377 NC_012578.1 399336 400454 D class V aminotransferase 399336..400454 Vibrio cholerae M66-2 7771664 YP_002809155.1 CDS VCM66_0378 NC_012578.1 400533 402326 R hypothetical protein complement(400533..402326) Vibrio cholerae M66-2 7771665 YP_002809156.1 CDS uvrA NC_012578.1 402382 405204 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(402382..405204) Vibrio cholerae M66-2 7771666 YP_002809157.1 CDS galU NC_012578.1 405360 406235 R UTP--glucose-1-phosphate uridylyltransferase complement(405360..406235) Vibrio cholerae M66-2 7771667 YP_002809158.1 CDS VCM66_0381 NC_012578.1 406405 407049 R LuxR family transcriptional regulator complement(406405..407049) Vibrio cholerae M66-2 7771668 YP_002809159.1 CDS ssb NC_012578.1 407341 407874 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 407341..407874 Vibrio cholerae M66-2 7771669 YP_002809160.1 CDS mshH NC_012578.1 407989 410010 D regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 407989..410010 Vibrio cholerae M66-2 7771670 YP_002809161.1 CDS mshI NC_012578.1 410023 411462 D MSHA biogenesis protein MshI 410023..411462 Vibrio cholerae M66-2 7771671 YP_002809162.1 CDS mshJ NC_012578.1 411459 412109 D MSHA biogenesis protein MshJ 411459..412109 Vibrio cholerae M66-2 7771672 YP_002809163.1 CDS mshK NC_012578.1 412102 412419 D MSHA biogenesis protein MshK 412102..412419 Vibrio cholerae M66-2 7771673 YP_002809164.1 CDS mshL NC_012578.1 412434 414113 D MSHA biogenesis protein MshL 412434..414113 Vibrio cholerae M66-2 7771674 YP_002809165.1 CDS mshM NC_012578.1 414118 414963 D MSHA biogenesis protein MshM 414118..414963 Vibrio cholerae M66-2 7771675 YP_002809166.1 CDS mshN NC_012578.1 414942 416111 D MSHA biogenesis protein MshN 414942..416111 Vibrio cholerae M66-2 7771676 YP_002809167.1 CDS mshE NC_012578.1 416101 417828 D MSHA biogenesis protein MshE 416101..417828 Vibrio cholerae M66-2 7771677 YP_002809168.1 CDS mshG NC_012578.1 417837 419060 D MSHA biogenesis protein MshG 417837..419060 Vibrio cholerae M66-2 7771678 YP_002809169.1 CDS mshF NC_012578.1 419063 419515 D MSHA biogenesis protein MshF 419063..419515 Vibrio cholerae M66-2 7771679 YP_002809170.1 CDS mshB NC_012578.1 419560 420150 D MSHA pilin protein MshB 419560..420150 Vibrio cholerae M66-2 7771680 YP_002809171.1 CDS mshA NC_012578.1 420176 420712 D MSHA pilin protein MshA 420176..420712 Vibrio cholerae M66-2 7771681 YP_002809172.1 CDS mshC NC_012578.1 420749 421237 D MSHA pilin protein MshC 420749..421237 Vibrio cholerae M66-2 7771682 YP_002809173.1 CDS mshD NC_012578.1 421185 421796 D MSHA pilin protein MshD 421185..421796 Vibrio cholerae M66-2 7771683 YP_002809174.1 CDS VCM66_0397 NC_012578.1 421796 422566 D hypothetical protein 421796..422566 Vibrio cholerae M66-2 7771684 YP_002809175.1 CDS VCM66_0398 NC_012578.1 422532 422963 D hypothetical protein 422532..422963 Vibrio cholerae M66-2 7771685 YP_002809176.1 CDS VCM66_0399 NC_012578.1 422956 426714 D hypothetical protein 422956..426714 Vibrio cholerae M66-2 7771686 YP_002809177.1 CDS mreB NC_012578.1 426882 427925 D functions in MreBCD complex in some organisms; rod shape-determining protein MreB 426882..427925 Vibrio cholerae M66-2 7771687 YP_002809178.1 CDS mreC NC_012578.1 427982 428872 D in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 427982..428872 Vibrio cholerae M66-2 7771688 YP_002809179.1 CDS mreD NC_012578.1 428859 429347 D part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 428859..429347 Vibrio cholerae M66-2 7771689 YP_002809180.1 CDS maf NC_012578.1 429290 429907 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 429290..429907 Vibrio cholerae M66-2 7771690 YP_002809181.1 CDS cafA NC_012578.1 429933 431402 D involved in the processing of the 5'end of 16S rRNA; ribonuclease G 429933..431402 Vibrio cholerae M66-2 7771691 YP_002809182.1 CDS VCM66_0405 NC_012578.1 431415 435290 D hypothetical protein 431415..435290 Vibrio cholerae M66-2 7771692 YP_002809183.1 CDS VCM66_0406 NC_012578.1 435299 436126 D hypothetical protein 435299..436126 Vibrio cholerae M66-2 7771693 YP_002809184.1 CDS tldD NC_012578.1 436126 437571 D tldD protein 436126..437571 Vibrio cholerae M66-2 7771694 YP_002809185.1 CDS arcA NC_012578.1 437667 438890 R catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase complement(437667..438890) Vibrio cholerae M66-2 7771695 YP_002809186.1 CDS VCM66_0409 NC_012578.1 439617 440039 D hypothetical protein 439617..440039 Vibrio cholerae M66-2 7771696 YP_002809187.1 CDS VCM66_0410 NC_012578.1 440186 440983 D hypothetical protein 440186..440983 Vibrio cholerae M66-2 7771697 YP_002809188.1 CDS VCM66_0411 NC_012578.1 441052 441435 R hypothetical protein complement(441052..441435) Vibrio cholerae M66-2 7771698 YP_002809189.1 CDS VCM66_0412 NC_012578.1 441454 441564 D hypothetical protein 441454..441564 Vibrio cholerae M66-2 7771699 YP_002809190.1 CDS VCM66_0413 NC_012578.1 441586 442023 R Universal stress protein F complement(441586..442023) Vibrio cholerae M66-2 7771700 YP_002809191.1 CDS VCM66_0414 NC_012578.1 442145 444709 R hypothetical protein complement(442145..444709) Vibrio cholerae M66-2 7771701 YP_002809192.1 CDS VCM66_0415 NC_012578.1 444880 445866 R immunogenic protein complement(444880..445866) Vibrio cholerae M66-2 7771702 YP_002809193.1 CDS argR NC_012578.1 446172 446705 R regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor complement(446172..446705) Vibrio cholerae M66-2 7771703 YP_002809194.1 CDS mdh NC_012578.1 446844 447905 D oxidizes malate to oxaloacetate; malate dehydrogenase 446844..447905 Vibrio cholerae M66-2 7771704 YP_002809195.1 CDS VCM66_0418 NC_012578.1 448379 449785 D arginine/ornithine antiporter 448379..449785 Vibrio cholerae M66-2 7771705 YP_002809196.1 CDS ispB NC_012578.1 449934 450980 R octaprenyl-diphosphate synthase complement(449934..450980) Vibrio cholerae M66-2 7771706 YP_002809197.1 CDS rplU NC_012578.1 451176 451487 D 50S ribosomal protein L21 451176..451487 Vibrio cholerae M66-2 7771707 YP_002809198.1 CDS rpmA NC_012578.1 451508 451768 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 451508..451768 Vibrio cholerae M66-2 7771708 YP_002809199.1 CDS obgE NC_012578.1 451969 453156 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 451969..453156 Vibrio cholerae M66-2 7771709 YP_002809200.1 CDS VCM66_0423 NC_012578.1 453170 454039 D putative Inner membrane protein 453170..454039 Vibrio cholerae M66-2 7771710 YP_002809201.1 CDS VCM66_0424 NC_012578.1 454027 454512 D hypothetical protein 454027..454512 Vibrio cholerae M66-2 7771711 YP_002809202.1 CDS folA NC_012578.1 454525 455022 D dihydrofolate reductase 454525..455022 Vibrio cholerae M66-2 7771712 YP_002809203.1 CDS apaH NC_012578.1 455171 455980 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(455171..455980) Vibrio cholerae M66-2 7771713 YP_002809204.1 CDS apaG NC_012578.1 455991 456371 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(455991..456371) Vibrio cholerae M66-2 7771714 YP_002809205.1 CDS ksgA NC_012578.1 456443 457291 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(456443..457291) Vibrio cholerae M66-2 7771715 YP_002809206.1 CDS pdxA NC_012578.1 457272 458264 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(457272..458264) Vibrio cholerae M66-2 7771716 YP_002809207.1 CDS surA NC_012578.1 458254 459549 R survival protein SurA complement(458254..459549) Vibrio cholerae M66-2 7771717 YP_002809208.1 CDS imp NC_012578.1 459602 462001 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(459602..462001) Vibrio cholerae M66-2 7771718 YP_002809209.1 CDS djlA NC_012578.1 462148 463002 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 462148..463002 Vibrio cholerae M66-2 7771719 YP_002809210.1 CDS VCM66_0434 NC_012578.1 464049 465674 R methyl-accepting chemotaxis protein complement(464049..465674) Vibrio cholerae M66-2 7774057 YP_002809211.1 CDS mltC NC_012578.1 466438 467628 R membrane-bound lytic murein transglycosylase C complement(466438..467628) Vibrio cholerae M66-2 7774055 YP_002809212.1 CDS VCM66_0436 NC_012578.1 467667 467939 R hypothetical protein complement(467667..467939) Vibrio cholerae M66-2 7771722 YP_002809213.1 CDS mutY NC_012578.1 467953 469014 R A/G-specific adenine glycosylase complement(467953..469014) Vibrio cholerae M66-2 7771723 YP_002809214.1 CDS trmB NC_012578.1 469254 469973 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 469254..469973 Vibrio cholerae M66-2 7771724 YP_002809215.1 CDS VCM66_0439 NC_012578.1 470054 471004 D catalyzes the formation of glutamate from glutamine; glutaminase 470054..471004 Vibrio cholerae M66-2 7771725 YP_002809216.1 CDS VCM66_0440 NC_012578.1 471239 472414 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(471239..472414) Vibrio cholerae M66-2 7771726 YP_002809217.1 CDS VCM66_0441 NC_012578.1 472408 473010 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase complement(472408..473010) Vibrio cholerae M66-2 7771727 YP_002809218.1 CDS VCM66_0442 NC_012578.1 473080 473511 R hypothetical protein complement(473080..473511) Vibrio cholerae M66-2 7771728 YP_002809219.1 CDS VCM66_0443 NC_012578.1 473557 473847 R hypothetical protein complement(473557..473847) Vibrio cholerae M66-2 7771729 YP_002809220.1 CDS VCM66_0444 NC_012578.1 473847 474404 R hypothetical protein complement(473847..474404) Vibrio cholerae M66-2 7771730 YP_002809221.1 CDS proC NC_012578.1 474458 475276 R catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase complement(474458..475276) Vibrio cholerae M66-2 7771731 YP_002809222.1 CDS VCM66_0446 NC_012578.1 475329 476039 R hypothetical protein complement(475329..476039) Vibrio cholerae M66-2 7771732 YP_002809223.1 CDS pilT-1 NC_012578.1 476065 477102 D twitching motility protein PilT 476065..477102 Vibrio cholerae M66-2 7771733 YP_002809224.1 CDS pilT-2 NC_012578.1 477117 478223 D twitching motility protein PilT 477117..478223 Vibrio cholerae M66-2 7771734 YP_002809225.1 CDS VCM66_0449 NC_012578.1 478335 479138 D LuxR family transcriptional regulator 478335..479138 Vibrio cholerae M66-2 7771735 YP_002809226.1 CDS tyrS-1 NC_012578.1 479223 480527 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 479223..480527 Vibrio cholerae M66-2 7771736 YP_002809227.1 CDS VCM66_0451 NC_012578.1 480565 480987 R similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein complement(480565..480987) Vibrio cholerae M66-2 7771737 YP_002809228.1 CDS VCM66_0452 NC_012578.1 481068 481670 R hypothetical protein complement(481068..481670) Vibrio cholerae M66-2 7771738 YP_002809229.1 CDS gshB NC_012578.1 481667 482623 R catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase complement(481667..482623) Vibrio cholerae M66-2 7771739 YP_002809230.1 CDS VCM66_0454 NC_012578.1 482637 483368 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(482637..483368) Vibrio cholerae M66-2 7771740 YP_002809231.1 CDS dns NC_012578.1 483506 484201 R extracellular deoxyribonuclease complement(483506..484201) Vibrio cholerae M66-2 7771741 YP_002809232.1 CDS VCM66_0456 NC_012578.1 484329 484817 R hypothetical protein complement(484329..484817) Vibrio cholerae M66-2 7771742 YP_002809233.1 CDS metK NC_012578.1 484939 486096 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(484939..486096) Vibrio cholerae M66-2 7771743 YP_002809234.1 CDS tktA-1 NC_012578.1 486374 488458 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 486374..488458 Vibrio cholerae M66-2 7771744 YP_002809235.1 CDS irgB NC_012578.1 488530 489426 R iron-regulated virulence regulatory protein IrgB complement(488530..489426) Vibrio cholerae M66-2 7771745 YP_002809236.1 CDS irgA NC_012578.1 489571 491529 D IrgA; binds ferric enterobactin; irgA gene expression is repressed by Fur and induced by the divergently transcribed upstream gene irgB; outer membrane protein; involved in iron metabolism; enterobactin receptor protein 489571..491529 Vibrio cholerae M66-2 7771746 YP_002809237.1 CDS epd NC_012578.1 491549 492706 D NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 491549..492706 Vibrio cholerae M66-2 7771747 YP_002809238.1 CDS pgk NC_012578.1 492840 494018 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 492840..494018 Vibrio cholerae M66-2 7771748 YP_002809239.1 CDS fbaA NC_012578.1 494174 495250 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 494174..495250 Vibrio cholerae M66-2 7771749 YP_002809240.1 CDS VCM66_0464 NC_012578.1 495438 495533 D hypothetical protein 495438..495533 Vibrio cholerae M66-2 7771750 YP_002809241.1 CDS VCM66_0465 NC_012578.1 495546 496409 D Small-conductance mechanosensitive channel 495546..496409 Vibrio cholerae M66-2 7771751 YP_002809242.1 CDS VCM66_0466 NC_012578.1 496473 497108 R LysE/YggA family protein complement(496473..497108) Vibrio cholerae M66-2 7771752 YP_002809243.1 CDS iciA NC_012578.1 497273 498169 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 497273..498169 Vibrio cholerae M66-2 7771753 YP_002809244.1 CDS VCM66_0468 NC_012578.1 498249 498965 D hypothetical protein 498249..498965 Vibrio cholerae M66-2 7771754 YP_002809245.1 CDS VCM66_0469 NC_012578.1 499298 499429 D hypothetical protein 499298..499429 Vibrio cholerae M66-2 7771755 YP_002809246.1 CDS pykF NC_012578.1 499501 500913 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(499501..500913) Vibrio cholerae M66-2 7771756 YP_002809247.1 CDS VCM66_0471 NC_012578.1 501329 502111 D DeoR family transcriptional regulator 501329..502111 Vibrio cholerae M66-2 7771757 YP_002809248.1 CDS glmS NC_012578.1 502174 504006 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 502174..504006 Vibrio cholerae M66-2 7771758 YP_002809249.1 CDS VCM66_0473 NC_012578.1 504067 505146 R putative extracellular solute-binding protein complement(504067..505146) Vibrio cholerae M66-2 7771759 YP_002809250.1 CDS VCM66_0474 NC_012578.1 505403 507163 R putative hemolysin complement(505403..507163) Vibrio cholerae M66-2 7771760 YP_002809251.1 CDS rpoD NC_012578.1 507852 509729 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(507852..509729) Vibrio cholerae M66-2 7774054 YP_002809252.1 CDS dnaG NC_012578.1 509828 511591 R synthesizes RNA primers at the replication forks; DNA primase complement(509828..511591) Vibrio cholerae M66-2 7771762 YP_002809253.1 CDS VCM66_0477 NC_012578.1 511681 512124 R hypothetical protein complement(511681..512124) Vibrio cholerae M66-2 7771763 YP_002809254.1 CDS rpsU NC_012578.1 512154 512369 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(512154..512369) Vibrio cholerae M66-2 7771764 YP_002809255.1 CDS gcp NC_012578.1 512610 513629 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 512610..513629 Vibrio cholerae M66-2 7771765 YP_002809256.1 CDS VCM66_0480 NC_012578.1 513783 514595 D putative beta-ketoadipate enol-lactone hydrolase 513783..514595 Vibrio cholerae M66-2 7771766 YP_002809257.1 CDS VCM66_0481 NC_012578.1 514644 515270 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; putative glycerol-3-phosphate acyltransferase PlsY complement(514644..515270) Vibrio cholerae M66-2 7771767 YP_002809258.1 CDS VCM66_0482 NC_012578.1 515423 515812 D putative dihydroneopterin aldolase FolB 515423..515812 Vibrio cholerae M66-2 7771768 YP_002809259.1 CDS folK-1 NC_012578.1 515728 516315 D 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 515728..516315 Vibrio cholerae M66-2 7771769 YP_002809260.1 CDS VCM66_0484 NC_012578.1 516312 517115 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 516312..517115 Vibrio cholerae M66-2 7771770 YP_002809261.1 CDS ftsB NC_012578.1 517224 517514 D forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 517224..517514 Vibrio cholerae M66-2 7771771 YP_002809262.1 CDS ispD NC_012578.1 517511 518209 D 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 517511..518209 Vibrio cholerae M66-2 7771772 YP_002809263.1 CDS ispF NC_012578.1 518206 518682 D catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 518206..518682 Vibrio cholerae M66-2 7771773 YP_002809264.1 CDS truD NC_012578.1 518712 519797 D catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 518712..519797 Vibrio cholerae M66-2 7771774 YP_002809265.1 CDS surE NC_012578.1 519760 520551 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 519760..520551 Vibrio cholerae M66-2 7771775 YP_002809266.1 CDS pcm NC_012578.1 520544 521170 D catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 520544..521170 Vibrio cholerae M66-2 7771776 YP_002809267.1 CDS nlpD NC_012578.1 521170 522105 D lipoprotein NlpD 521170..522105 Vibrio cholerae M66-2 7771777 YP_002809268.1 CDS rpoS NC_012578.1 522179 523186 D RNA polymerase sigma factor RpoS 522179..523186 Vibrio cholerae M66-2 7771778 YP_002809269.1 CDS mutS NC_012578.1 523279 525867 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(523279..525867) Vibrio cholerae M66-2 7771779 YP_002809270.1 CDS VCM66_0494 NC_012578.1 525874 525975 D hypothetical protein 525874..525975 Vibrio cholerae M66-2 7771780 YP_002809271.1 CDS cysM NC_012578.1 526135 527022 R catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B complement(526135..527022) Vibrio cholerae M66-2 7771781 YP_002809272.1 CDS cysP NC_012578.1 527406 528407 D thiosulfate ABC transporter periplasmic thiosulfate-binding protein 527406..528407 Vibrio cholerae M66-2 7771782 YP_002809273.1 CDS cysT NC_012578.1 528484 529335 D sulfate ABC transporter permease 528484..529335 Vibrio cholerae M66-2 7771783 YP_002809274.1 CDS cysW NC_012578.1 529346 530209 D sulfate ABC transporter permease 529346..530209 Vibrio cholerae M66-2 7771784 YP_002809275.1 CDS cysA NC_012578.1 530206 531336 D sulfate ABC transporter ATP-binding protein 530206..531336 Vibrio cholerae M66-2 7771785 YP_002809276.1 CDS VCM66_0500 NC_012578.1 531503 532009 D CinA-like protein 531503..532009 Vibrio cholerae M66-2 7771786 YP_002809277.1 CDS recA NC_012578.1 531969 533207 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 531969..533207 Vibrio cholerae M66-2 7771787 YP_002809278.1 CDS recX NC_012578.1 533340 533798 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 533340..533798 Vibrio cholerae M66-2 7771788 YP_002809279.1 CDS alaS NC_012578.1 533971 536553 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 533971..536553 Vibrio cholerae M66-2 7771789 YP_002809280.1 CDS VCM66_0504 NC_012578.1 536585 536704 D hypothetical protein 536585..536704 Vibrio cholerae M66-2 7771790 YP_002809281.1 CDS VCM66_0505 NC_012578.1 536757 537944 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; aspartate kinase 536757..537944 Vibrio cholerae M66-2 7771791 YP_002809282.1 CDS csrA NC_012578.1 538036 538233 D affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 538036..538233 Vibrio cholerae M66-2 7771792 YP_002809283.1 CDS VCM66_0507 NC_012578.1 539711 540064 D oxaloacetate decarboxylase subunit gamma 539711..540064 Vibrio cholerae M66-2 7774001 YP_002809284.1 CDS oadA-1 NC_012578.1 540093 541886 D catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase 540093..541886 Vibrio cholerae M66-2 7771794 YP_002809285.1 CDS oadB-1 NC_012578.1 541896 543026 D oxaloacetate decarboxylase subunit beta 541896..543026 Vibrio cholerae M66-2 7771795 YP_002809286.1 CDS VCM66_0510 NC_012578.1 543086 544099 D quinone oxidoreductase 543086..544099 Vibrio cholerae M66-2 7771796 YP_002809287.1 CDS VCM66_0511 NC_012578.1 544093 544554 D putative Inner membrane protein 544093..544554 Vibrio cholerae M66-2 7771797 YP_002809288.1 CDS VCM66_0512 NC_012578.1 544561 547419 D protease, insulinase family/protease, insulinase family 544561..547419 Vibrio cholerae M66-2 7771798 YP_002809289.1 CDS VCM66_0513 NC_012578.1 547409 547510 R hypothetical protein complement(547409..547510) Vibrio cholerae M66-2 7771799 YP_002809290.1 CDS gshA NC_012578.1 547531 549105 D involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 547531..549105 Vibrio cholerae M66-2 7771800 YP_002809291.1 CDS luxS NC_012578.1 549154 549672 D catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 549154..549672 Vibrio cholerae M66-2 7771801 YP_002809292.1 CDS VCM66_0516 NC_012578.1 549742 551022 R putative hemolysin complement(549742..551022) Vibrio cholerae M66-2 7771802 YP_002809293.1 CDS VCM66_0517 NC_012578.1 551105 551908 R putative Inner membrane protein complement(551105..551908) Vibrio cholerae M66-2 7771803 YP_002809294.1 CDS ffh NC_012578.1 552112 553497 D signal recognition particle protein 552112..553497 Vibrio cholerae M66-2 7771804 YP_002809295.1 CDS rpsP NC_012578.1 553733 553981 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 553733..553981 Vibrio cholerae M66-2 7771805 YP_002809296.1 CDS rimM NC_012578.1 554009 554563 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 554009..554563 Vibrio cholerae M66-2 7771806 YP_002809297.1 CDS trmD NC_012578.1 554591 555334 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 554591..555334 Vibrio cholerae M66-2 7771807 YP_002809298.1 CDS rplS NC_012578.1 555376 555729 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 555376..555729 Vibrio cholerae M66-2 7771808 YP_002809299.1 CDS degS NC_012578.1 555850 556908 R protease DegS complement(555850..556908) Vibrio cholerae M66-2 7771809 YP_002809300.1 CDS htrA NC_012578.1 557085 558455 R protease DO complement(557085..558455) Vibrio cholerae M66-2 7771810 YP_002809301.1 CDS VCM66_0525 NC_012578.1 558584 559021 R cytochrome d ubiquinol oxidase subunit III complement(558584..559021) Vibrio cholerae M66-2 7771811 YP_002809302.1 CDS VCM66_0526 NC_012578.1 559175 560278 D hypothetical protein 559175..560278 Vibrio cholerae M66-2 7771812 YP_002809303.1 CDS VCM66_0527 NC_012578.1 560208 560417 R hypothetical protein complement(560208..560417) Vibrio cholerae M66-2 7771813 YP_002809304.1 CDS rplM NC_012578.1 560502 560930 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 560502..560930 Vibrio cholerae M66-2 7771814 YP_002809305.1 CDS rpsI NC_012578.1 560946 561338 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 560946..561338 Vibrio cholerae M66-2 7771815 YP_002809306.1 CDS VCM66_0530 NC_012578.1 561348 561473 D hypothetical protein 561348..561473 Vibrio cholerae M66-2 7771816 YP_002809307.1 CDS petA NC_012578.1 561666 562259 D ubiquinol--cytochrome c reductase, iron-sulfur subunit 561666..562259 Vibrio cholerae M66-2 7771817 YP_002809308.1 CDS petB NC_012578.1 562259 563524 D ubiquinol--cytochrome c reductase, cytochrome B 562259..563524 Vibrio cholerae M66-2 7771818 YP_002809309.1 CDS petC NC_012578.1 563521 564258 D ubiquinol--cytochrome c reductase, cytochrome c1 563521..564258 Vibrio cholerae M66-2 7771819 YP_002809310.1 CDS sspA NC_012578.1 564358 564993 D transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 564358..564993 Vibrio cholerae M66-2 7771820 YP_002809311.1 CDS sspB NC_012578.1 564993 565469 D ClpXP protease specificity-enhancing factor 564993..565469 Vibrio cholerae M66-2 7771821 YP_002809312.1 CDS VCM66_0536 NC_012578.1 565537 566106 R putative hemolysin complement(565537..566106) Vibrio cholerae M66-2 7771822 YP_002809313.1 CDS VCM66_0537 NC_012578.1 566109 566699 R putative phosphoheptose isomerase complement(566109..566699) Vibrio cholerae M66-2 7771823 YP_002809314.1 CDS VCM66_0538 NC_012578.1 566703 567071 R hypothetical protein complement(566703..567071) Vibrio cholerae M66-2 7771824 YP_002809315.1 CDS VCM66_0539 NC_012578.1 567058 569019 R putative lipoprotein complement(567058..569019) Vibrio cholerae M66-2 7771825 YP_002809316.1 CDS VCM66_0540 NC_012578.1 568933 569799 D hypothetical protein 568933..569799 Vibrio cholerae M66-2 7771826 YP_002809317.1 CDS hapR NC_012578.1 569877 570623 R hemagglutinin/protease regulatory protein complement(569877..570623) Vibrio cholerae M66-2 7771827 YP_002809318.1 CDS VCM66_0542 NC_012578.1 570838 570954 R hypothetical protein complement(570838..570954) Vibrio cholerae M66-2 7771828 YP_002809319.1 CDS hpt NC_012578.1 570919 571452 D hypoxanthine phosphoribosyltransferase 570919..571452 Vibrio cholerae M66-2 7771829 YP_002809320.1 CDS VCM66_0544 NC_012578.1 571527 572195 R putative carbonic anhydrase complement(571527..572195) Vibrio cholerae M66-2 7771830 YP_002809321.1 CDS VCM66_0545 NC_012578.1 572343 573989 D sulfate permease family protein 572343..573989 Vibrio cholerae M66-2 7771831 YP_002809322.1 CDS VCM66_0546 NC_012578.1 574097 574198 D hypothetical protein 574097..574198 Vibrio cholerae M66-2 7771832 YP_002809323.1 CDS VCM66_0547 NC_012578.1 574373 575290 D ABC transporter ATP-binding protein 574373..575290 Vibrio cholerae M66-2 7771833 YP_002809324.1 CDS VCM66_0548 NC_012578.1 575296 576066 D putative permease 575296..576066 Vibrio cholerae M66-2 7771834 YP_002809325.1 CDS panC NC_012578.1 576130 577011 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(576130..577011) Vibrio cholerae M66-2 7771835 YP_002809326.1 CDS panB NC_012578.1 577022 577816 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(577022..577816) Vibrio cholerae M66-2 7771836 YP_002809327.1 CDS folK-2 NC_012578.1 577819 578322 R 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(577819..578322) Vibrio cholerae M66-2 7771837 YP_002809328.1 CDS pcnB NC_012578.1 578319 579692 R polyA polymerase complement(578319..579692) Vibrio cholerae M66-2 7771838 YP_002809329.1 CDS VCM66_0553 NC_012578.1 579783 580673 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(579783..580673) Vibrio cholerae M66-2 7771839 YP_002809330.1 CDS dksA NC_012578.1 580747 581193 R dnaK suppressor protein complement(580747..581193) Vibrio cholerae M66-2 7771840 YP_002809331.1 CDS sfsA NC_012578.1 581318 582088 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(581318..582088) Vibrio cholerae M66-2 7771841 YP_002809332.1 CDS VCM66_0556 NC_012578.1 582076 582177 D hypothetical protein 582076..582177 Vibrio cholerae M66-2 7771842 YP_002809333.1 CDS VCM66_0558 NC_012578.1 582299 583651 D hypothetical protein 582299..583651 Vibrio cholerae M66-2 7771843 YP_002809334.1 CDS mrcB NC_012578.1 586209 588542 D penicillin-binding protein 1B 586209..588542 Vibrio cholerae M66-2 7773953 YP_002809335.1 CDS VCM66_0561 NC_012578.1 588779 591073 D hypothetical protein 588779..591073 Vibrio cholerae M66-2 7771845 YP_002809336.1 CDS acnB NC_012578.1 591338 593935 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 591338..593935 Vibrio cholerae M66-2 7771846 YP_002809337.1 CDS VCM66_0563 NC_012578.1 594090 594470 D hypothetical protein 594090..594470 Vibrio cholerae M66-2 7771847 YP_002809338.1 CDS glnB-1 NC_012578.1 594621 594986 D nitrogen regulatory protein P-II 594621..594986 Vibrio cholerae M66-2 7771848 YP_002809339.1 CDS VCM66_0565 NC_012578.1 595008 596237 D putative ammonium transporter 595008..596237 Vibrio cholerae M66-2 7771849 YP_002809340.1 CDS fbpA NC_012578.1 596334 597392 D iron(III) ABC transporter periplasmic iron-compound-binding protein 596334..597392 Vibrio cholerae M66-2 7771850 YP_002809341.1 CDS fbpB NC_012578.1 597476 599101 D iron(III) ABC transporter permease 597476..599101 Vibrio cholerae M66-2 7771851 YP_002809342.1 CDS fbpC NC_012578.1 599101 600132 D iron(III) ABC transporter ATP-binding protein 599101..600132 Vibrio cholerae M66-2 7771852 YP_002809343.1 CDS VCM66_0569 NC_012578.1 600263 601675 R putative phosphoglucomutase/phosphomannomutase complement(600263..601675) Vibrio cholerae M66-2 7771853 YP_002809344.1 CDS VCM66_0570 NC_012578.1 601798 604203 R putative cellobiose/cellodextrin-phosphorylase complement(601798..604203) Vibrio cholerae M66-2 7771854 YP_002809345.1 CDS chb-1 NC_012578.1 604322 606235 R beta-N-acetylhexosaminidase complement(604322..606235) Vibrio cholerae M66-2 7771855 YP_002809346.1 CDS VCM66_0572 NC_012578.1 606232 607209 R N-acetylglucosamine kinase complement(606232..607209) Vibrio cholerae M66-2 7771856 YP_002809347.1 CDS VCM66_0573 NC_012578.1 607113 608837 R endoglucanase-like protein complement(607113..608837) Vibrio cholerae M66-2 7771857 YP_002809348.1 CDS VCM66_0574 NC_012578.1 608894 609889 R peptide ABC transporter ATP-binding protein complement(608894..609889) Vibrio cholerae M66-2 7771858 YP_002809349.1 CDS VCM66_0575 NC_012578.1 609932 610915 R peptide ABC transporter ATP-binding protein complement(609932..610915) Vibrio cholerae M66-2 7771859 YP_002809350.1 CDS VCM66_0576 NC_012578.1 610918 611943 R peptide ABC transporter permease complement(610918..611943) Vibrio cholerae M66-2 7771860 YP_002809351.1 CDS VCM66_0577 NC_012578.1 611946 612932 R peptide ABC transporter permease complement(611946..612932) Vibrio cholerae M66-2 7771861 YP_002809352.1 CDS VCM66_0578 NC_012578.1 613102 614772 R peptide ABC transporter substrate-binding protein complement(613102..614772) Vibrio cholerae M66-2 7771862 YP_002809353.1 CDS VCM66_0579 NC_012578.1 615345 615734 D hypothetical protein 615345..615734 Vibrio cholerae M66-2 7771863 YP_002809354.1 CDS VCM66_0580 NC_012578.1 615683 619216 R sensory box sensor histidine kinase/response regulator complement(615683..619216) Vibrio cholerae M66-2 7771864 YP_002809355.1 CDS VCM66_0581 NC_012578.1 619280 620302 R Ribosomal RNA small subunit methyltransferase C complement(619280..620302) Vibrio cholerae M66-2 7771865 YP_002809356.1 CDS VCM66_0582 NC_012578.1 620375 621460 R hypothetical protein complement(620375..621460) Vibrio cholerae M66-2 7771866 YP_002809357.1 CDS VCM66_0583 NC_012578.1 621497 621652 D hypothetical protein 621497..621652 Vibrio cholerae M66-2 7771867 YP_002809358.1 CDS hemL NC_012578.1 621714 623012 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(621714..623012) Vibrio cholerae M66-2 7771868 YP_002809359.1 CDS VCM66_0585 NC_012578.1 623296 623637 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 623296..623637 Vibrio cholerae M66-2 7771869 YP_002809360.1 CDS VCM66_0586 NC_012578.1 623735 624835 D Nodulation protein nolF 623735..624835 Vibrio cholerae M66-2 7771870 YP_002809361.1 CDS VCM66_0587 NC_012578.1 624744 627965 D putative multidrug resistance protein 624744..627965 Vibrio cholerae M66-2 7771871 YP_002809362.1 CDS VCM66_0588 NC_012578.1 628047 629348 R hypothetical protein complement(628047..629348) Vibrio cholerae M66-2 7771872 YP_002809363.1 CDS tyrS-2 NC_012578.1 629479 630666 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 629479..630666 Vibrio cholerae M66-2 7771873 YP_002809364.1 CDS dacB NC_012578.1 630734 632197 R penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase complement(630734..632197) Vibrio cholerae M66-2 7771874 YP_002809365.1 CDS ompU NC_012578.1 632277 633329 R outer membrane protein OmpU complement(632277..633329) Vibrio cholerae M66-2 7771875 YP_002809366.1 CDS greA NC_012578.1 633853 634329 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 633853..634329 Vibrio cholerae M66-2 7771876 YP_002809367.1 CDS VCM66_0593 NC_012578.1 634406 634702 R hypothetical protein complement(634406..634702) Vibrio cholerae M66-2 7771877 YP_002809368.1 CDS rrmJ NC_012578.1 634822 635451 D Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 634822..635451 Vibrio cholerae M66-2 7771878 YP_002809369.1 CDS ftsH NC_012578.1 635552 637507 D cell division protein FtsH 635552..637507 Vibrio cholerae M66-2 7771879 YP_002809370.1 CDS folP NC_012578.1 637574 638410 D dihydropteroate synthase 637574..638410 Vibrio cholerae M66-2 7771880 YP_002809371.1 CDS glmM NC_012578.1 638436 639776 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 638436..639776 Vibrio cholerae M66-2 7771881 YP_002809372.1 CDS secG NC_012578.1 640033 640368 D preprotein translocase subunit SecG 640033..640368 Vibrio cholerae M66-2 7771882 YP_002809373.1 CDS VCM66_0599 NC_012578.1 640799 641254 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 640799..641254 Vibrio cholerae M66-2 7774050 YP_002809374.1 CDS nusA NC_012578.1 641273 642760 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 641273..642760 Vibrio cholerae M66-2 7771884 YP_002809375.1 CDS infB NC_012578.1 642785 645481 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 642785..645481 Vibrio cholerae M66-2 7771885 YP_002809376.1 CDS rbfA NC_012578.1 645571 645981 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 645571..645981 Vibrio cholerae M66-2 7771886 YP_002809377.1 CDS truB NC_012578.1 645981 646919 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 645981..646919 Vibrio cholerae M66-2 7771887 YP_002809378.1 CDS rpsO NC_012578.1 647061 647330 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 647061..647330 Vibrio cholerae M66-2 7771888 YP_002809379.1 CDS pnp NC_012578.1 647693 649822 D polynucleotide phosphorylase/polyadenylase 647693..649822 Vibrio cholerae M66-2 7771889 YP_002809380.1 CDS VCM66_0606 NC_012578.1 649938 650849 D lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 649938..650849 Vibrio cholerae M66-2 7771890 YP_002809381.1 CDS VCM66_0607 NC_012578.1 650936 651355 D MarR family transcriptional regulator 650936..651355 Vibrio cholerae M66-2 7771891 YP_002809382.1 CDS vmrA NC_012578.1 651402 652739 D sodium/drug antiporter; functions as a Na(+)-driven Na(+)/drug antiporter; member of multidrug and toxic compound extrusion (MATE) family; extrudes acriflavines and other compounds by utilizing the sodium gradient; multidrug efflux pump VmrA 651402..652739 Vibrio cholerae M66-2 7771892 YP_002809383.1 CDS VCM66_0609 NC_012578.1 652792 653757 R hypothetical protein complement(652792..653757) Vibrio cholerae M66-2 7771893 YP_002809384.1 CDS VCM66_0610 NC_012578.1 653682 654695 R putative protease complement(653682..654695) Vibrio cholerae M66-2 7771894 YP_002809385.1 CDS VCM66_0611 NC_012578.1 654803 656857 R c-di-GMP phosphodiesterase A-like protein complement(654803..656857) Vibrio cholerae M66-2 7771895 YP_002809386.1 CDS VCM66_0612 NC_012578.1 657090 657617 D hypothetical protein 657090..657617 Vibrio cholerae M66-2 7771896 YP_002809387.1 CDS VCM66_0613 NC_012578.1 657553 658104 D putative acetyltransferase 657553..658104 Vibrio cholerae M66-2 7771897 YP_002809388.1 CDS holD NC_012578.1 658215 658622 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 658215..658622 Vibrio cholerae M66-2 7771898 YP_002809389.1 CDS rimI NC_012578.1 658583 659068 D ribosomal-protein-alanine acetyltransferase 658583..659068 Vibrio cholerae M66-2 7771899 YP_002809390.1 CDS VCM66_0616 NC_012578.1 659057 661114 R c-di-GMP phosphodiesterase A-like protein complement(659057..661114) Vibrio cholerae M66-2 7771900 YP_002809391.1 CDS prfC NC_012578.1 661318 662913 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 661318..662913 Vibrio cholerae M66-2 7771901 YP_002809392.1 CDS srmB NC_012578.1 663035 664306 R facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB complement(663035..664306) Vibrio cholerae M66-2 7771902 YP_002809393.1 CDS VCM66_0619 NC_012578.1 664394 665116 R hypothetical protein complement(664394..665116) Vibrio cholerae M66-2 7771903 YP_002809394.1 CDS brnQ NC_012578.1 665425 666738 D branched chain amino acid transport system II carrier protein 665425..666738 Vibrio cholerae M66-2 7771904 YP_002809395.1 CDS prfB NC_012578.1 667107 668006 D peptide chain release factor 2 667107..668006 Vibrio cholerae M66-2 7771905 YP_002809396.1 CDS lysS NC_012578.1 668031 669569 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 668031..669569 Vibrio cholerae M66-2 7771906 YP_002809397.1 CDS VCM66_0623 NC_012578.1 669843 671177 D sigma-54 dependent transcriptional regulator 669843..671177 Vibrio cholerae M66-2 7771907 YP_002809398.1 CDS VCM66_0624 NC_012578.1 671692 672006 D hypothetical protein 671692..672006 Vibrio cholerae M66-2 7771908 YP_002809399.1 CDS VCM66_0625 NC_012578.1 672044 673102 R oxidoreductase Tas, aldo/keto reductase family complement(672044..673102) Vibrio cholerae M66-2 7771909 YP_002809400.1 CDS mutH NC_012578.1 673295 673960 R MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein complement(673295..673960) Vibrio cholerae M66-2 7771910 YP_002809401.1 CDS VCM66_0627 NC_012578.1 674347 674439 R hypothetical protein complement(674347..674439) Vibrio cholerae M66-2 7771911 YP_002809402.1 CDS VCM66_0628 NC_012578.1 674422 674568 D hypothetical protein 674422..674568 Vibrio cholerae M66-2 7771912 YP_002809403.1 CDS VCM66_0629 NC_012578.1 674528 675109 D hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 674528..675109 Vibrio cholerae M66-2 7771913 YP_002809404.1 CDS ptsP NC_012578.1 675112 677358 D member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain 675112..677358 Vibrio cholerae M66-2 7771914 YP_002809405.1 CDS VCM66_0631 NC_012578.1 677368 678162 D hypothetical protein 677368..678162 Vibrio cholerae M66-2 7771915 YP_002809406.1 CDS lgt NC_012578.1 678191 679006 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 678191..679006 Vibrio cholerae M66-2 7771916 YP_002809407.1 CDS thyA NC_012578.1 679016 679867 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 679016..679867 Vibrio cholerae M66-2 7771917 YP_002809408.1 CDS ntpA NC_012578.1 679960 681108 R nptA protein complement(679960..681108) Vibrio cholerae M66-2 7771918 YP_002809409.1 CDS nhaR NC_012578.1 681503 682393 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 681503..682393 Vibrio cholerae M66-2 7771919 YP_002809410.1 CDS hlyU NC_012578.1 682592 682918 D transcriptional activator HlyU 682592..682918 Vibrio cholerae M66-2 7771920 YP_002809411.1 CDS rpsT NC_012578.1 682987 683247 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(682987..683247) Vibrio cholerae M66-2 7771921 YP_002809412.1 CDS mviN NC_012578.1 683490 685067 D MviN protein 683490..685067 Vibrio cholerae M66-2 7771922 YP_002809413.1 CDS ribF NC_012578.1 685136 686104 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 685136..686104 Vibrio cholerae M66-2 7771923 YP_002809414.1 CDS ileS NC_012578.1 686135 688984 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 686135..688984 Vibrio cholerae M66-2 7771924 YP_002809415.1 CDS lspA NC_012578.1 689000 689515 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 689000..689515 Vibrio cholerae M66-2 7771925 YP_002809416.1 CDS fkpB NC_012578.1 689678 690112 D FKBP-type peptidyl-prolyl cis-trans isomerase 689678..690112 Vibrio cholerae M66-2 7771926 YP_002809417.1 CDS ispH NC_012578.1 690147 691109 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 690147..691109 Vibrio cholerae M66-2 7771927 YP_002809418.1 CDS VCM66_0644 NC_012578.1 691140 691235 D hypothetical protein 691140..691235 Vibrio cholerae M66-2 7771928 YP_002809419.1 CDS VCM66_0645 NC_012578.1 691246 692730 R putative carbon starvation protein A complement(691246..692730) Vibrio cholerae M66-2 7771929 YP_002809420.1 CDS VCM66_0646 NC_012578.1 692983 693324 D putative lipoprotein 692983..693324 Vibrio cholerae M66-2 7771930 YP_002809421.1 CDS VCM66_0647 NC_012578.1 693340 695139 D putative Cell volume regulation protein 693340..695139 Vibrio cholerae M66-2 7771931 YP_002809422.1 CDS VCM66_0648 NC_012578.1 695163 696086 R catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase complement(695163..696086) Vibrio cholerae M66-2 7771932 YP_002809423.1 CDS anmK NC_012578.1 696104 697216 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(696104..697216) Vibrio cholerae M66-2 7771933 YP_002809424.1 CDS exoII NC_012578.1 697322 698314 D hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 697322..698314 Vibrio cholerae M66-2 7771934 YP_002809425.1 CDS VCM66_0651 NC_012578.1 698341 699054 R unknown function; when overproduced it confers drug-resistance; putative two-component response-regulatory protein YehT complement(698341..699054) Vibrio cholerae M66-2 7771935 YP_002809426.1 CDS VCM66_0652 NC_012578.1 699064 700740 R GAF/HisKin family protein complement(699064..700740) Vibrio cholerae M66-2 7771936 YP_002809427.1 CDS aroF NC_012578.1 700982 702055 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 700982..702055 Vibrio cholerae M66-2 7771937 YP_002809428.1 CDS tyrA NC_012578.1 702068 703195 D catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 702068..703195 Vibrio cholerae M66-2 7771938 YP_002809429.1 CDS VCM66_0655 NC_012578.1 703262 703693 R hypothetical protein complement(703262..703693) Vibrio cholerae M66-2 7771939 YP_002809430.1 CDS VCM66_0656 NC_012578.1 703804 705471 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein complement(703804..705471) Vibrio cholerae M66-2 7771940 YP_002809431.1 CDS VCM66_0657 NC_012578.1 705656 705751 D hypothetical protein 705656..705751 Vibrio cholerae M66-2 7771941 YP_002809432.1 CDS VCM66_0659 NC_012578.1 707790 708146 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 707790..708146 Vibrio cholerae M66-2 7773954 YP_002809433.1 CDS VCM66_0660 NC_012578.1 708224 708775 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(708224..708775) Vibrio cholerae M66-2 7771943 YP_002809434.1 CDS mbaA NC_012578.1 708696 711071 R c-di-GMP phosphodiesterase A-like protein complement(708696..711071) Vibrio cholerae M66-2 7771944 YP_002809435.1 CDS VCM66_0662 NC_012578.1 711055 712134 R putative spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein complement(711055..712134) Vibrio cholerae M66-2 7771945 YP_002809436.1 CDS pheA NC_012578.1 712277 713452 R chorismate mutase/prephenate dehydratase complement(712277..713452) Vibrio cholerae M66-2 7771946 YP_002809437.1 CDS VCM66_0664 NC_012578.1 713692 714018 R putative sigma-54 modulation protein complement(713692..714018) Vibrio cholerae M66-2 7771947 YP_002809438.1 CDS VCM66_0665 NC_012578.1 714297 714425 D hypothetical protein 714297..714425 Vibrio cholerae M66-2 7771948 YP_002809439.1 CDS VCM66_0666 NC_012578.1 714420 715181 R hypothetical protein complement(714420..715181) Vibrio cholerae M66-2 7771949 YP_002809440.1 CDS rluD NC_012578.1 715300 716274 D responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 715300..716274 Vibrio cholerae M66-2 7771950 YP_002809441.1 CDS VCM66_0668 NC_012578.1 716277 716999 D hypothetical protein 716277..716999 Vibrio cholerae M66-2 7771951 YP_002809442.1 CDS clpB-1 NC_012578.1 717124 719697 D clpB protein 717124..719697 Vibrio cholerae M66-2 7771952 YP_002809443.1 CDS VCM66_0670 NC_012578.1 719946 720038 D hypothetical protein 719946..720038 Vibrio cholerae M66-2 7771953 YP_002809444.1 CDS VCM66_0672 NC_012578.1 725668 725991 D hypothetical protein 725668..725991 Vibrio cholerae M66-2 7774010 YP_002809445.1 CDS frp NC_012578.1 726001 726723 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 726001..726723 Vibrio cholerae M66-2 7771955 YP_002809446.1 CDS VCM66_0674 NC_012578.1 726758 727012 R ferredoxin complement(726758..727012) Vibrio cholerae M66-2 7771956 YP_002809447.1 CDS VCM66_0675 NC_012578.1 727015 728415 R putative protease complement(727015..728415) Vibrio cholerae M66-2 7771957 YP_002809448.1 CDS rdgC NC_012578.1 728566 729480 R Required for efficient pilin antigenic variation; recombination associated protein complement(728566..729480) Vibrio cholerae M66-2 7771958 YP_002809449.1 CDS phoB NC_012578.1 729717 730406 D DNA-binding response regulator PhoB 729717..730406 Vibrio cholerae M66-2 7771959 YP_002809450.1 CDS phoR NC_012578.1 730428 731729 D membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 730428..731729 Vibrio cholerae M66-2 7771960 YP_002809451.1 CDS VCM66_0679 NC_012578.1 731726 732703 D putative phosphate ABC transporter periplasmic phosphate-binding protein 731726..732703 Vibrio cholerae M66-2 7771961 YP_002809452.1 CDS ppx NC_012578.1 732771 734342 R exopolyphosphatase complement(732771..734342) Vibrio cholerae M66-2 7771962 YP_002809453.1 CDS ppk NC_012578.1 734254 736359 R catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase complement(734254..736359) Vibrio cholerae M66-2 7771963 YP_002809454.1 CDS pstC-1 NC_012578.1 736558 738753 D phosphate ABC transporter permease 736558..738753 Vibrio cholerae M66-2 7771964 YP_002809455.1 CDS pstA-1 NC_012578.1 738763 740409 D phosphate ABC transporter permease 738763..740409 Vibrio cholerae M66-2 7771965 YP_002809456.1 CDS pstB-1 NC_012578.1 740412 741233 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 740412..741233 Vibrio cholerae M66-2 7771966 YP_002809457.1 CDS phoU NC_012578.1 741267 741977 D regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 741267..741977 Vibrio cholerae M66-2 7771967 YP_002809458.1 CDS VCM66_0686 NC_012578.1 742038 742814 R hypothetical protein complement(742038..742814) Vibrio cholerae M66-2 7771968 YP_002809459.1 CDS VCM66_0687 NC_012578.1 742867 742968 D hypothetical protein 742867..742968 Vibrio cholerae M66-2 7771969 YP_002809460.1 CDS cutC NC_012578.1 743017 743781 R copper homeostasis protein complement(743017..743781) Vibrio cholerae M66-2 7771970 YP_002809461.1 CDS VCM66_0689 NC_012578.1 744116 744739 R antioxidant, AhpC/Tsa family complement(744116..744739) Vibrio cholerae M66-2 7771971 YP_002809462.1 CDS VCM66_0690 NC_012578.1 744943 745848 D LysR family transcriptional regulator 744943..745848 Vibrio cholerae M66-2 7771972 YP_002809463.1 CDS VCM66_0691 NC_012578.1 746083 746202 R hypothetical protein complement(746083..746202) Vibrio cholerae M66-2 7771973 YP_002809464.1 CDS aceB NC_012578.1 746399 748069 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 746399..748069 Vibrio cholerae M66-2 7771974 YP_002809465.1 CDS VCM66_0693 NC_012578.1 748074 748175 R hypothetical protein complement(748074..748175) Vibrio cholerae M66-2 7771975 YP_002809466.1 CDS aceA NC_012578.1 748199 749512 D isocitrate lyase 748199..749512 Vibrio cholerae M66-2 7771976 YP_002809467.1 CDS VCM66_0695 NC_012578.1 749665 750174 R acetoin utilization protein complement(749665..750174) Vibrio cholerae M66-2 7771977 YP_002809468.1 CDS VCM66_0696 NC_012578.1 750238 750342 D hypothetical protein 750238..750342 Vibrio cholerae M66-2 7771978 YP_002809469.1 CDS queA NC_012578.1 750404 751462 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 750404..751462 Vibrio cholerae M66-2 7771979 YP_002809470.1 CDS VCM66_0698 NC_012578.1 751417 751680 R hypothetical protein complement(751417..751680) Vibrio cholerae M66-2 7771980 YP_002809471.1 CDS tgt NC_012578.1 751691 752830 D Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 751691..752830 Vibrio cholerae M66-2 7771981 YP_002809472.1 CDS yajC NC_012578.1 752935 753267 D member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 752935..753267 Vibrio cholerae M66-2 7771982 YP_002809473.1 CDS secD NC_012578.1 753289 755142 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 753289..755142 Vibrio cholerae M66-2 7771983 YP_002809474.1 CDS secF NC_012578.1 755157 756104 D forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 755157..756104 Vibrio cholerae M66-2 7771984 YP_002809475.1 CDS VCM66_0703 NC_012578.1 756272 757138 R inositol monophosphate family protein complement(756272..757138) Vibrio cholerae M66-2 7771985 YP_002809476.1 CDS VCM66_0704 NC_012578.1 757254 757988 D RNA methyltransferase, TrmH family 757254..757988 Vibrio cholerae M66-2 7771986 YP_002809477.1 CDS VCM66_0705 NC_012578.1 758058 758624 D hypothetical protein 758058..758624 Vibrio cholerae M66-2 7771987 YP_002809478.1 CDS VCM66_0706 NC_012578.1 758651 759865 D catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 758651..759865 Vibrio cholerae M66-2 7771988 YP_002809479.1 CDS VCM66_0707 NC_012578.1 759902 760285 D scaffold protein 759902..760285 Vibrio cholerae M66-2 7771989 YP_002809480.1 CDS VCM66_0708 NC_012578.1 760346 760669 D hesB family protein 760346..760669 Vibrio cholerae M66-2 7771990 YP_002809481.1 CDS hscB NC_012578.1 760718 761233 D J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 760718..761233 Vibrio cholerae M66-2 7771991 YP_002809482.1 CDS hscA NC_012578.1 761257 763107 D involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 761257..763107 Vibrio cholerae M66-2 7771992 YP_002809483.1 CDS VCM66_0711 NC_012578.1 763040 763459 D ferredoxin 763040..763459 Vibrio cholerae M66-2 7771993 YP_002809484.1 CDS VCM66_0712 NC_012578.1 763508 763702 D hypothetical protein 763508..763702 Vibrio cholerae M66-2 7771994 YP_002809485.1 CDS pepB NC_012578.1 763877 765211 D catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 763877..765211 Vibrio cholerae M66-2 7771995 YP_002809486.1 CDS ndk NC_012578.1 765415 765843 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 765415..765843 Vibrio cholerae M66-2 7771996 YP_002809487.1 CDS VCM66_0715 NC_012578.1 766017 767138 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 766017..767138 Vibrio cholerae M66-2 7771997 YP_002809488.1 CDS VCM66_0716 NC_012578.1 767353 768534 D Putative HTH-type transcriptional regulator yfgA 767353..768534 Vibrio cholerae M66-2 7771998 YP_002809489.1 CDS ispG NC_012578.1 768539 769669 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 768539..769669 Vibrio cholerae M66-2 7771999 YP_002809490.1 CDS hisS NC_012578.1 769695 770963 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 769695..770963 Vibrio cholerae M66-2 7772000 YP_002809491.1 CDS VCM66_0719 NC_012578.1 771000 771614 D hypothetical protein 771000..771614 Vibrio cholerae M66-2 7772001 YP_002809492.1 CDS VCM66_0720 NC_012578.1 771627 772787 D with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 771627..772787 Vibrio cholerae M66-2 7772002 YP_002809493.1 CDS engA NC_012578.1 772980 774464 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 772980..774464 Vibrio cholerae M66-2 7772003 YP_002809494.1 CDS VCM66_0722 NC_012578.1 774485 775402 D hypothetical protein 774485..775402 Vibrio cholerae M66-2 7772004 YP_002809495.1 CDS VCM66_0723 NC_012578.1 775707 775940 D hypothetical protein 775707..775940 Vibrio cholerae M66-2 7772005 YP_002809496.1 CDS xseA NC_012578.1 775921 777261 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(775921..777261) Vibrio cholerae M66-2 7772006 YP_002809497.1 CDS guaB NC_012578.1 777463 778932 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 777463..778932 Vibrio cholerae M66-2 7772007 YP_002809498.1 CDS guaA NC_012578.1 779039 780592 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 779039..780592 Vibrio cholerae M66-2 7772008 YP_002809499.1 CDS VCM66_0727 NC_012578.1 780828 782552 D putative chitinase 780828..782552 Vibrio cholerae M66-2 7772009 YP_002809500.1 CDS VCM66_0728 NC_012578.1 782743 783336 D putative Inner membrane protein 782743..783336 Vibrio cholerae M66-2 7772010 YP_002809501.1 CDS vibB NC_012578.1 783648 784529 D vibriobactin-specific isochorismatase 783648..784529 Vibrio cholerae M66-2 7772011 YP_002809502.1 CDS vibE NC_012578.1 784630 786261 R vibriobactin-specific 2,3-dihydroxybenzoate-AMP ligase complement(784630..786261) Vibrio cholerae M66-2 7772012 YP_002809503.1 CDS vibC NC_012578.1 786272 787459 R vibriobactin-specific isochorismate synthase complement(786272..787459) Vibrio cholerae M66-2 7772013 YP_002809504.1 CDS vibA NC_012578.1 787627 788415 D catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 787627..788415 Vibrio cholerae M66-2 7772014 YP_002809505.1 CDS vibH NC_012578.1 788427 789743 R vibriobactin synthetase, amide synthase subunit VibH complement(788427..789743) Vibrio cholerae M66-2 7772015 YP_002809506.1 CDS viuP NC_012578.1 789921 790898 D with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 789921..790898 Vibrio cholerae M66-2 7772016 YP_002809507.1 CDS viuD NC_012578.1 790895 791947 D vibriobactin and enterobactin ABC transporter permease 790895..791947 Vibrio cholerae M66-2 7772017 YP_002809508.1 CDS viuG NC_012578.1 791926 793002 D vibriobactin and enterobactin ABC transporter permease 791926..793002 Vibrio cholerae M66-2 7772018 YP_002809509.1 CDS viuC NC_012578.1 793119 793958 D vibriobactin and enterobactin ABC transporter ATP-binding protein 793119..793958 Vibrio cholerae M66-2 7772019 YP_002809510.1 CDS vibD NC_012578.1 793889 794674 D vibriobactin synthase component D 793889..794674 Vibrio cholerae M66-2 7772020 YP_002809511.1 CDS VCM66_0739 NC_012578.1 794684 795610 D LysR family transcriptional regulator 794684..795610 Vibrio cholerae M66-2 7772021 YP_002809512.1 CDS VCM66_0740 NC_012578.1 795603 795713 R hypothetical protein complement(795603..795713) Vibrio cholerae M66-2 7772022 YP_002809513.1 CDS VCM66_0741 NC_012578.1 795828 797810 D hypothetical protein 795828..797810 Vibrio cholerae M66-2 7772023 YP_002809514.1 CDS VCM66_0742 NC_012578.1 797890 799440 R sodium/alanine symporter complement(797890..799440) Vibrio cholerae M66-2 7772024 YP_002809515.1 CDS VCM66_0743 NC_012578.1 799719 799817 R hypothetical protein complement(799719..799817) Vibrio cholerae M66-2 7772025 YP_002809516.1 CDS dadA NC_012578.1 799818 801083 R catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit complement(799818..801083) Vibrio cholerae M66-2 7772026 YP_002809517.1 CDS VCM66_0745 NC_012578.1 801184 802116 D LysR family transcriptional regulator 801184..802116 Vibrio cholerae M66-2 7772027 YP_002809518.1 CDS VCM66_0746 NC_012578.1 802241 802570 D DOPA-dioxygenase-like protein 802241..802570 Vibrio cholerae M66-2 7772028 YP_002809519.1 CDS VCM66_0747 NC_012578.1 802736 803008 D hypothetical protein 802736..803008 Vibrio cholerae M66-2 7772029 YP_002809520.1 CDS citB NC_012578.1 803042 803725 R transcriptional regulator CitB complement(803042..803725) Vibrio cholerae M66-2 7772030 YP_002809521.1 CDS citA NC_012578.1 803739 805436 R sensor kinase citA complement(803739..805436) Vibrio cholerae M66-2 7772031 YP_002809522.1 CDS oadB-2 NC_012578.1 805507 806808 R oxaloacetate decarboxylase subunit beta complement(805507..806808) Vibrio cholerae M66-2 7772032 YP_002809523.1 CDS oadA-2 NC_012578.1 806824 808623 R catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase complement(806824..808623) Vibrio cholerae M66-2 7772033 YP_002809524.1 CDS VCM66_0752 NC_012578.1 808642 809061 R putative oxaloacetate decarboxylase gamma chain 2 complement(808642..809061) Vibrio cholerae M66-2 7772034 YP_002809525.1 CDS citS NC_012578.1 809009 810355 R citrate/sodium symporter complement(809009..810355) Vibrio cholerae M66-2 7772035 YP_002809526.1 CDS citC NC_012578.1 810617 811687 D citrate (pro-3S)-lyase ligase 810617..811687 Vibrio cholerae M66-2 7772036 YP_002809527.1 CDS citD NC_012578.1 811739 812035 D acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 811739..812035 Vibrio cholerae M66-2 7772037 YP_002809528.1 CDS citE NC_012578.1 812017 812907 D citrate lyase subunit beta 812017..812907 Vibrio cholerae M66-2 7772038 YP_002809529.1 CDS citF NC_012578.1 812843 814447 D citrate lyase subunit alpha 812843..814447 Vibrio cholerae M66-2 7772039 YP_002809530.1 CDS citX NC_012578.1 814444 814980 D citX protein 814444..814980 Vibrio cholerae M66-2 7772040 YP_002809531.1 CDS citG NC_012578.1 814958 815899 D citG protein 814958..815899 Vibrio cholerae M66-2 7772041 YP_002809532.1 CDS VCM66_0760 NC_012578.1 816246 816644 D hypothetical protein 816246..816644 Vibrio cholerae M66-2 7772042 YP_002809533.1 CDS VCM66_0761 NC_012578.1 816719 817492 D RNA methyltransferase, TrmH family 816719..817492 Vibrio cholerae M66-2 7772043 YP_002809534.1 CDS VCM66_0762 NC_012578.1 817671 817994 R ferredoxin complement(817671..817994) Vibrio cholerae M66-2 7772044 YP_002809535.1 CDS VCM66_0763 NC_012578.1 818036 818131 D hypothetical protein 818036..818131 Vibrio cholerae M66-2 7772045 YP_002809536.1 CDS VCM66_0764 NC_012578.1 818241 819857 D hypothetical protein 818241..819857 Vibrio cholerae M66-2 7772046 YP_002809537.1 CDS VCM66_0765 NC_012578.1 819925 820608 R hypothetical protein complement(819925..820608) Vibrio cholerae M66-2 7772047 YP_002809538.1 CDS VCM66_0766 NC_012578.1 820580 820732 R hypothetical protein complement(820580..820732) Vibrio cholerae M66-2 7772048 YP_002809539.1 CDS VCM66_0767 NC_012578.1 820741 822510 D hypothetical protein 820741..822510 Vibrio cholerae M66-2 7772049 YP_002809540.1 CDS VCM66_0768 NC_012578.1 822702 823217 D hypothetical protein 822702..823217 Vibrio cholerae M66-2 7772050 YP_002809541.1 CDS VCM66_0769 NC_012578.1 823551 824255 R hypothetical protein complement(823551..824255) Vibrio cholerae M66-2 7772051 YP_002809542.1 CDS VCM66_0770 NC_012578.1 824325 827264 R helicase-like protein complement(824325..827264) Vibrio cholerae M66-2 7772052 YP_002809543.1 CDS VCM66_0771 NC_012578.1 827265 827843 R tellurite resistance protein-like protein complement(827265..827843) Vibrio cholerae M66-2 7772053 YP_002809544.1 CDS VCM66_0772 NC_012578.1 828271 828750 R putative transcriptional regulator complement(828271..828750) Vibrio cholerae M66-2 7772054 YP_002809545.1 CDS VCM66_0773 NC_012578.1 828735 830105 R hypothetical protein complement(828735..830105) Vibrio cholerae M66-2 7772055 YP_002809546.1 CDS VCM66_0774 NC_012578.1 830216 830398 R hypothetical protein complement(830216..830398) Vibrio cholerae M66-2 7772056 YP_002809547.1 CDS VCM66_0775 NC_012578.1 830694 831677 D ISVch1 transposase, IS481 group 830694..831677 Vibrio cholerae M66-2 7772057 YP_002809548.1 CDS aldA-1 NC_012578.1 832725 834350 R aldehyde dehydrogenase complement(832725..834350) Vibrio cholerae M66-2 7773955 YP_002809549.1 CDS tagA NC_012578.1 834426 837467 D ToxR-activated gene A protein 834426..837467 Vibrio cholerae M66-2 7772059 YP_002809550.1 CDS VCM66_0779 NC_012578.1 837580 842181 D hypothetical protein 837580..842181 Vibrio cholerae M66-2 7772060 YP_002809551.1 CDS VCM66_0780 NC_012578.1 842178 843116 D hypothetical protein 842178..843116 Vibrio cholerae M66-2 7772061 YP_002809552.1 CDS tpx NC_012578.1 843226 843720 D antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 843226..843720 Vibrio cholerae M66-2 7772062 YP_002809553.1 CDS tcpI NC_012578.1 843996 845858 R toxin co-regulated pilus biosynthesis protein I complement(843996..845858) Vibrio cholerae M66-2 7772063 YP_002809554.1 CDS tcpP NC_012578.1 846298 846963 D toxin co-regulated pilus biosynthesis protein P 846298..846963 Vibrio cholerae M66-2 7772064 YP_002809555.1 CDS tcpH NC_012578.1 846948 847358 D toxin co-regulated pilus biosynthesis protein H 846948..847358 Vibrio cholerae M66-2 7772065 YP_002809556.1 CDS tcpA NC_012578.1 847901 848575 D toxin co-regulated pilin 847901..848575 Vibrio cholerae M66-2 7772066 YP_002809557.1 CDS tcpB NC_012578.1 848655 849947 D toxin co-regulated pilus biosynthesis protein B 848655..849947 Vibrio cholerae M66-2 7772067 YP_002809558.1 CDS tcpQ NC_012578.1 849947 850399 D toxin co-regulated pilus biosynthesis protein Q 849947..850399 Vibrio cholerae M66-2 7772068 YP_002809559.1 CDS tcpC NC_012578.1 850402 851871 D toxin co-regulated pilus biosynthesis outer membrane protein C 850402..851871 Vibrio cholerae M66-2 7772069 YP_002809560.1 CDS tcpR NC_012578.1 851864 852319 D toxin co-regulated pilus biosynthesis protein R 851864..852319 Vibrio cholerae M66-2 7772070 YP_002809561.1 CDS tcpD NC_012578.1 852307 853143 D toxin co-regulated pilus biosynthesis protein D 852307..853143 Vibrio cholerae M66-2 7772071 YP_002809562.1 CDS tcpS NC_012578.1 853159 853617 D toxin co-regulated pilus biosynthesis protein S 853159..853617 Vibrio cholerae M66-2 7772072 YP_002809563.1 CDS tcpT NC_012578.1 853607 855118 D toxin co-regulated pilus biosynthesis protein T 853607..855118 Vibrio cholerae M66-2 7772073 YP_002809564.1 CDS tcpE NC_012578.1 855093 856115 D toxin co-regulated pilus biosynthesis protein E 855093..856115 Vibrio cholerae M66-2 7772074 YP_002809565.1 CDS tcpF NC_012578.1 856125 857141 D toxin co-regulated pilus biosynthesis protein F 856125..857141 Vibrio cholerae M66-2 7772075 YP_002809566.1 CDS VCM66_0795 NC_012578.1 857348 858178 D TCP pilus virulence regulatory protein 857348..858178 Vibrio cholerae M66-2 7772076 YP_002809567.1 CDS tcpJ NC_012578.1 858178 858939 D leader peptidase TcpJ 858178..858939 Vibrio cholerae M66-2 7772077 YP_002809568.1 CDS acfB NC_012578.1 858946 860826 D accessory colonization factor AcfB 858946..860826 Vibrio cholerae M66-2 7772078 YP_002809569.1 CDS acfC NC_012578.1 860832 861602 D accessory colonization factor AcfC 860832..861602 Vibrio cholerae M66-2 7772079 YP_002809570.1 CDS VCM66_0799 NC_012578.1 861618 862091 D hypothetical protein 861618..862091 Vibrio cholerae M66-2 7772080 YP_002809571.1 CDS tagE-1 NC_012578.1 862100 863008 D tagE protein 862100..863008 Vibrio cholerae M66-2 7772081 YP_002809572.1 CDS acfA NC_012578.1 863011 863658 R accessory colonization factor AcfA complement(863011..863658) Vibrio cholerae M66-2 7772082 YP_002809573.1 CDS VCM66_0802 NC_012578.1 863831 868393 D putative lipoprotein 863831..868393 Vibrio cholerae M66-2 7772083 YP_002809574.1 CDS VCM66_0804 NC_012578.1 870308 871576 R integrase, phage family complement(870308..871576) Vibrio cholerae M66-2 7773956 YP_002809575.1 CDS smpB NC_012578.1 872178 872663 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(872178..872663) Vibrio cholerae M66-2 7772085 YP_002809576.1 CDS VCM66_0806 NC_012578.1 872841 873281 D hypothetical protein 872841..873281 Vibrio cholerae M66-2 7772086 YP_002809577.1 CDS VCM66_0807 NC_012578.1 873278 873589 D hypothetical protein 873278..873589 Vibrio cholerae M66-2 7772087 YP_002809578.1 CDS smpA NC_012578.1 873667 874077 R small protein A complement(873667..874077) Vibrio cholerae M66-2 7772088 YP_002809579.1 CDS recN NC_012578.1 874185 875849 R recombination and repair protein complement(874185..875849) Vibrio cholerae M66-2 7772089 YP_002809580.1 CDS ppnK NC_012578.1 875979 876863 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(875979..876863) Vibrio cholerae M66-2 7772090 YP_002809581.1 CDS grpE NC_012578.1 877009 877611 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 877009..877611 Vibrio cholerae M66-2 7772091 YP_002809582.1 CDS dnaK NC_012578.1 877875 879782 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 877875..879782 Vibrio cholerae M66-2 7772092 YP_002809583.1 CDS dnaJ NC_012578.1 879983 881128 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 879983..881128 Vibrio cholerae M66-2 7772093 YP_002809584.1 CDS VCM66_0814 NC_012578.1 881178 881621 R putative fimbrial assembly protein PilE complement(881178..881621) Vibrio cholerae M66-2 7772094 YP_002809585.1 CDS VCM66_0815 NC_012578.1 881676 882230 D putative type IV pilin 881676..882230 Vibrio cholerae M66-2 7772095 YP_002809586.1 CDS VCM66_0816 NC_012578.1 882199 882801 D hypothetical protein 882199..882801 Vibrio cholerae M66-2 7772096 YP_002809587.1 CDS VCM66_0817 NC_012578.1 882792 884033 D hypothetical protein 882792..884033 Vibrio cholerae M66-2 7772097 YP_002809588.1 CDS VCM66_0818 NC_012578.1 884023 884436 D putative type IV pilin 884023..884436 Vibrio cholerae M66-2 7772098 YP_002809589.1 CDS VCM66_0819 NC_012578.1 884473 884841 D hypothetical protein 884473..884841 Vibrio cholerae M66-2 7772099 YP_002809590.1 CDS VCM66_0820 NC_012578.1 884834 886393 D Aminobenzoyl-glutamate transport protein 884834..886393 Vibrio cholerae M66-2 7772100 YP_002809591.1 CDS yfhC NC_012578.1 886462 887043 D yfhC protein 886462..887043 Vibrio cholerae M66-2 7772101 YP_002809592.1 CDS VCM66_0822 NC_012578.1 887089 887220 R hypothetical protein complement(887089..887220) Vibrio cholerae M66-2 7772102 YP_002809593.1 CDS VCM66_0823 NC_012578.1 887399 888991 R YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; putative transglycosylase complement(887399..888991) Vibrio cholerae M66-2 7772103 YP_002809594.1 CDS VCM66_0824 NC_012578.1 888991 889113 R hypothetical protein complement(888991..889113) Vibrio cholerae M66-2 7772104 YP_002809595.1 CDS VCM66_0825 NC_012578.1 889092 889304 D hypothetical protein 889092..889304 Vibrio cholerae M66-2 7772105 YP_002809596.1 CDS purL NC_012578.1 889301 893194 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 889301..893194 Vibrio cholerae M66-2 7772106 YP_002809597.1 CDS tnpA NC_012578.1 893369 893806 D IS1004 transposase 893369..893806 Vibrio cholerae M66-2 7772107 YP_002809598.1 CDS VCM66_0828 NC_012578.1 893917 894108 R hypothetical protein complement(893917..894108) Vibrio cholerae M66-2 7772108 YP_002809599.1 CDS VCM66_0829 NC_012578.1 894114 894317 R hypothetical protein complement(894114..894317) Vibrio cholerae M66-2 7772109 YP_002809600.1 CDS VCM66_0830 NC_012578.1 894420 895064 R putative Inner membrane protein complement(894420..895064) Vibrio cholerae M66-2 7772110 YP_002809601.1 CDS VCM66_0831 NC_012578.1 895097 895288 D hypothetical protein 895097..895288 Vibrio cholerae M66-2 7772111 YP_002809602.1 CDS proS NC_012578.1 895306 897021 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(895306..897021) Vibrio cholerae M66-2 7772112 YP_002809603.1 CDS VCM66_0833 NC_012578.1 897247 897942 R hypothetical protein complement(897247..897942) Vibrio cholerae M66-2 7772113 YP_002809604.1 CDS VCM66_0834 NC_012578.1 897958 898056 R hypothetical protein complement(897958..898056) Vibrio cholerae M66-2 7772114 YP_002809605.1 CDS rpmE2 NC_012578.1 898077 898334 D RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B 898077..898334 Vibrio cholerae M66-2 7772115 YP_002809606.1 CDS rpmJ NC_012578.1 898331 898456 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 898331..898456 Vibrio cholerae M66-2 7772116 YP_002809607.1 CDS VCM66_0837 NC_012578.1 898639 900243 D Aminobenzoyl-glutamate transport protein 898639..900243 Vibrio cholerae M66-2 7772117 YP_002809608.1 CDS VCM66_0838 NC_012578.1 900309 900758 R hypothetical protein complement(900309..900758) Vibrio cholerae M66-2 7772118 YP_002809609.1 CDS VCM66_0839 NC_012578.1 900755 901054 R hypothetical protein complement(900755..901054) Vibrio cholerae M66-2 7772119 YP_002809610.1 CDS VCM66_0840 NC_012578.1 901667 901780 R hypothetical protein complement(901667..901780) Vibrio cholerae M66-2 7772120 YP_002809611.1 CDS VCM66_0841 NC_012578.1 901819 902442 D acetyltransferase-like protein 901819..902442 Vibrio cholerae M66-2 7772121 YP_002809612.1 CDS VCM66_0842 NC_012578.1 902399 902701 R hypothetical protein complement(902399..902701) Vibrio cholerae M66-2 7772122 YP_002809613.1 CDS VCM66_0843 NC_012578.1 902705 903742 R hypothetical protein complement(902705..903742) Vibrio cholerae M66-2 7772123 YP_002809614.1 CDS VCM66_0844 NC_012578.1 903831 904142 D hypothetical protein 903831..904142 Vibrio cholerae M66-2 7772124 YP_002809615.1 CDS VCM66_0845 NC_012578.1 904143 904877 D catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 904143..904877 Vibrio cholerae M66-2 7772125 YP_002809616.1 CDS dxs NC_012578.1 904975 906855 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(904975..906855) Vibrio cholerae M66-2 7772126 YP_002809617.1 CDS ispA NC_012578.1 906875 907759 R geranyltranstransferase complement(906875..907759) Vibrio cholerae M66-2 7772127 YP_002809618.1 CDS xseB NC_012578.1 907801 908043 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit complement(907801..908043) Vibrio cholerae M66-2 7772128 YP_002809619.1 CDS pomA NC_012578.1 908358 909122 D Homologous to MotA in E. coli and Salmonella. With PomB forms the ion channels that couple flagellar rotation to sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.; flagellar motor protein PomA 908358..909122 Vibrio cholerae M66-2 7772129 YP_002809620.1 CDS motB NC_012578.1 909134 910090 D with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar motor protein MotB 909134..910090 Vibrio cholerae M66-2 7772130 YP_002809621.1 CDS thiI NC_012578.1 910298 911845 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 910298..911845 Vibrio cholerae M66-2 7772131 YP_002809622.1 CDS VCM66_0853 NC_012578.1 912428 913348 D Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 912428..913348 Vibrio cholerae M66-2 7772132 YP_002809623.1 CDS VCM66_0854 NC_012578.1 913370 913756 D hypothetical protein 913370..913756 Vibrio cholerae M66-2 7772133 YP_002809624.1 CDS xni NC_012578.1 913787 914638 R has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX complement(913787..914638) Vibrio cholerae M66-2 7772134 YP_002809625.1 CDS VCM66_0856 NC_012578.1 914677 916050 R hypothetical protein complement(914677..916050) Vibrio cholerae M66-2 7772135 YP_002809626.1 CDS VCM66_0857 NC_012578.1 916255 917829 R GGDEF family protein complement(916255..917829) Vibrio cholerae M66-2 7772136 YP_002809627.1 CDS VCM66_0858 NC_012578.1 917931 920192 R hypothetical protein complement(917931..920192) Vibrio cholerae M66-2 7772137 YP_002809628.1 CDS queF NC_012578.1 920207 921070 R catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(920207..921070) Vibrio cholerae M66-2 7772138 YP_002809629.1 CDS syd NC_012578.1 921101 921697 D putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 921101..921697 Vibrio cholerae M66-2 7772139 YP_002809630.1 CDS VCM66_0861 NC_012578.1 921699 922475 D hypothetical protein 921699..922475 Vibrio cholerae M66-2 7772140 YP_002809631.1 CDS metQ NC_012578.1 922608 923435 R DL-methionine transporter substrate-binding subunit complement(922608..923435) Vibrio cholerae M66-2 7772141 YP_002809632.1 CDS VCM66_0863 NC_012578.1 923454 924131 R ABC transporter permease complement(923454..924131) Vibrio cholerae M66-2 7772142 YP_002809633.1 CDS metN NC_012578.1 924121 925155 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(924121..925155) Vibrio cholerae M66-2 7772143 YP_002809634.1 CDS VCM66_0865 NC_012578.1 925391 925951 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 925391..925951 Vibrio cholerae M66-2 7772144 YP_002809635.1 CDS treR NC_012578.1 926016 926966 D regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 926016..926966 Vibrio cholerae M66-2 7772145 YP_002809636.1 CDS treB NC_012578.1 927203 928639 D phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC 927203..928639 Vibrio cholerae M66-2 7772146 YP_002809637.1 CDS treC NC_012578.1 928719 930407 D trehalose-6-phosphate hydrolase 928719..930407 Vibrio cholerae M66-2 7772147 YP_002809638.1 CDS VCM66_0869 NC_012578.1 931182 931277 D hypothetical protein 931182..931277 Vibrio cholerae M66-2 7774075 YP_002809639.1 CDS VCM66_0870 NC_012578.1 931464 932522 D Multidrug resistance protein mdtA 931464..932522 Vibrio cholerae M66-2 7772149 YP_002809640.1 CDS VCM66_0871 NC_012578.1 932522 935632 D putative multidrug resistance protein 932522..935632 Vibrio cholerae M66-2 7772150 YP_002809641.1 CDS VCM66_0872 NC_012578.1 935687 935797 D hypothetical protein 935687..935797 Vibrio cholerae M66-2 7772151 YP_002809642.1 CDS VCM66_0873 NC_012578.1 936059 936559 D phosphotyrosine protein phosphatase 936059..936559 Vibrio cholerae M66-2 7772152 YP_002809643.1 CDS wecB NC_012578.1 936872 937990 D UDP-N-acetylglucosamine 2-epimerase 936872..937990 Vibrio cholerae M66-2 7772153 YP_002809644.1 CDS wecC NC_012578.1 938010 939251 D catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 938010..939251 Vibrio cholerae M66-2 7772154 YP_002809645.1 CDS VCM66_0876 NC_012578.1 939248 939802 D serine acetyltransferase-like protein 939248..939802 Vibrio cholerae M66-2 7772155 YP_002809646.1 CDS VCM66_0877 NC_012578.1 939799 940947 D putative exopolysaccharide biosynthesis protein 939799..940947 Vibrio cholerae M66-2 7772156 YP_002809647.1 CDS VCM66_0878 NC_012578.1 940944 942353 D putative polysaccharide export protein 940944..942353 Vibrio cholerae M66-2 7772157 YP_002809648.1 CDS VCM66_0879 NC_012578.1 942350 943570 D hypothetical protein 942350..943570 Vibrio cholerae M66-2 7772158 YP_002809649.1 CDS VCM66_0880 NC_012578.1 943581 944012 D serine acetyltransferase-like protein 943581..944012 Vibrio cholerae M66-2 7772159 YP_002809650.1 CDS VCM66_0881 NC_012578.1 944012 945352 D putative capK protein 944012..945352 Vibrio cholerae M66-2 7772160 YP_002809651.1 CDS VCM66_0882 NC_012578.1 945328 946425 D putative polysaccharide biosynthesis protein 945328..946425 Vibrio cholerae M66-2 7772161 YP_002809652.1 CDS VCM66_0883 NC_012578.1 946422 947594 D hypothetical protein 946422..947594 Vibrio cholerae M66-2 7772162 YP_002809653.1 CDS cpsF NC_012578.1 947584 948336 D UDP-N-acetyl-D-mannosamine transferase 947584..948336 Vibrio cholerae M66-2 7772163 YP_002809654.1 CDS VCM66_0885 NC_012578.1 948532 949347 D hypothetical protein 948532..949347 Vibrio cholerae M66-2 7772164 YP_002809655.1 CDS VCM66_0886 NC_012578.1 949553 950779 R hypothetical protein complement(949553..950779) Vibrio cholerae M66-2 7772165 YP_002809656.1 CDS VCM66_0887 NC_012578.1 951043 953916 D hemolysin-like protein 951043..953916 Vibrio cholerae M66-2 7772166 YP_002809657.1 CDS VCM66_0888 NC_012578.1 954071 955387 R hypothetical protein complement(954071..955387) Vibrio cholerae M66-2 7772167 YP_002809658.1 CDS VCM66_0889 NC_012578.1 955563 956168 R hypothetical protein complement(955563..956168) Vibrio cholerae M66-2 7772168 YP_002809659.1 CDS VCM66_0890 NC_012578.1 956658 958055 D putative capsular polysaccharide biosynthesis glycosyltransferase 956658..958055 Vibrio cholerae M66-2 7772169 YP_002809660.1 CDS VCM66_0891 NC_012578.1 958126 959322 D hypothetical protein 958126..959322 Vibrio cholerae M66-2 7772170 YP_002809661.1 CDS VCM66_0892 NC_012578.1 959326 959853 D polysaccharide export-like protein 959326..959853 Vibrio cholerae M66-2 7772171 YP_002809662.1 CDS VCM66_0893 NC_012578.1 959878 962091 D putative exopolysaccharide biosynthesis protein 959878..962091 Vibrio cholerae M66-2 7772172 YP_002809663.1 CDS VCM66_0894 NC_012578.1 962088 962795 D hypothetical protein 962088..962795 Vibrio cholerae M66-2 7772173 YP_002809664.1 CDS VCM66_0895 NC_012578.1 962774 963208 D hypothetical protein 962774..963208 Vibrio cholerae M66-2 7772174 YP_002809665.1 CDS VCM66_0896 NC_012578.1 963364 963960 R hypothetical protein complement(963364..963960) Vibrio cholerae M66-2 7772175 YP_002809666.1 CDS glyA NC_012578.1 964244 965551 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 964244..965551 Vibrio cholerae M66-2 7772176 YP_002809667.1 CDS VCM66_0898 NC_012578.1 965716 966069 R hypothetical protein complement(965716..966069) Vibrio cholerae M66-2 7772177 YP_002809668.1 CDS lipA NC_012578.1 966238 967203 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(966238..967203) Vibrio cholerae M66-2 7772178 YP_002809669.1 CDS lipB NC_012578.1 967196 967855 R lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B complement(967196..967855) Vibrio cholerae M66-2 7772179 YP_002809670.1 CDS VCM66_0901 NC_012578.1 968034 968312 R hypothetical protein complement(968034..968312) Vibrio cholerae M66-2 7772180 YP_002809671.1 CDS VCM66_0902 NC_012578.1 968334 968501 D hypothetical protein 968334..968501 Vibrio cholerae M66-2 7772181 YP_002809672.1 CDS dacA-1 NC_012578.1 968460 969635 R D-alanyl-D-alanine carboxypeptidase complement(968460..969635) Vibrio cholerae M66-2 7772182 YP_002809673.1 CDS VCM66_0904 NC_012578.1 969727 970518 R putative rare lipoprotein A complement(969727..970518) Vibrio cholerae M66-2 7772183 YP_002809674.1 CDS rodA NC_012578.1 970518 971639 R rod shape-determining protein RodA complement(970518..971639) Vibrio cholerae M66-2 7772184 YP_002809675.1 CDS mrdA NC_012578.1 971636 973552 R penicillin-binding protein 2 complement(971636..973552) Vibrio cholerae M66-2 7772185 YP_002809676.1 CDS VCM66_0907 NC_012578.1 973559 974029 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(973559..974029) Vibrio cholerae M66-2 7772186 YP_002809677.1 CDS VCM66_0908 NC_012578.1 974032 974349 R hypothetical protein complement(974032..974349) Vibrio cholerae M66-2 7772187 YP_002809678.1 CDS holA NC_012578.1 974418 975446 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta complement(974418..975446) Vibrio cholerae M66-2 7772188 YP_002809679.1 CDS rlpB NC_012578.1 975452 976093 R rare lipoprotein B complement(975452..976093) Vibrio cholerae M66-2 7772189 YP_002809680.1 CDS VCM66_0911 NC_012578.1 976109 976213 R hypothetical protein complement(976109..976213) Vibrio cholerae M66-2 7772190 YP_002809681.1 CDS leuS NC_012578.1 976243 978927 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(976243..978927) Vibrio cholerae M66-2 7772191 YP_002809682.1 CDS VCM66_0913 NC_012578.1 978949 979419 D hypothetical protein 978949..979419 Vibrio cholerae M66-2 7772192 YP_002809683.1 CDS lnt NC_012578.1 979475 980992 R Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase complement(979475..980992) Vibrio cholerae M66-2 7772193 YP_002809684.1 CDS VCM66_0915 NC_012578.1 981033 981908 R putative hemolysin complement(981033..981908) Vibrio cholerae M66-2 7772194 YP_002809685.1 CDS VCM66_0916 NC_012578.1 981978 982442 R putative metalloprotease complement(981978..982442) Vibrio cholerae M66-2 7772195 YP_002809686.1 CDS VCM66_0917 NC_012578.1 982439 983542 R phoH family protein complement(982439..983542) Vibrio cholerae M66-2 7772196 YP_002809687.1 CDS VCM66_0918 NC_012578.1 983610 985034 R catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase complement(983610..985034) Vibrio cholerae M66-2 7772197 YP_002809688.1 CDS VCM66_0919 NC_012578.1 985258 986451 D catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 985258..986451 Vibrio cholerae M66-2 7772198 YP_002809689.1 CDS crr NC_012578.1 986576 987085 R functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit complement(986576..987085) Vibrio cholerae M66-2 7772199 YP_002809690.1 CDS ptsI NC_012578.1 987194 988915 R Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase complement(987194..988915) Vibrio cholerae M66-2 7772200 YP_002809691.1 CDS ptsH NC_012578.1 989049 989306 R phosphocarrier protein HPr complement(989049..989306) Vibrio cholerae M66-2 7772201 YP_002809692.1 CDS VCM66_0923 NC_012578.1 989391 989600 R hypothetical protein complement(989391..989600) Vibrio cholerae M66-2 7772202 YP_002809693.1 CDS cysK NC_012578.1 989604 990572 R cysteine synthase A complement(989604..990572) Vibrio cholerae M66-2 7772203 YP_002809694.1 CDS cysZ NC_012578.1 990695 991447 R putative role in sulfur assimilation; putative sulfate transport protein CysZ complement(990695..991447) Vibrio cholerae M66-2 7772204 YP_002809695.1 CDS zipA NC_012578.1 991677 992552 D interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 991677..992552 Vibrio cholerae M66-2 7772205 YP_002809696.1 CDS ligA NC_012578.1 992685 994694 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 992685..994694 Vibrio cholerae M66-2 7772206 YP_002809697.1 CDS VCM66_0928 NC_012578.1 995326 996375 D putative porin 995326..996375 Vibrio cholerae M66-2 7772207 YP_002809698.1 CDS VCM66_0929 NC_012578.1 996452 997267 D hypothetical protein 996452..997267 Vibrio cholerae M66-2 7772208 YP_002809699.1 CDS VCM66_0930 NC_012578.1 997328 997747 D MerR family transcriptional regulator 997328..997747 Vibrio cholerae M66-2 7772209 YP_002809700.1 CDS VCM66_0931 NC_012578.1 997791 998360 R putative Inner membrane protein complement(997791..998360) Vibrio cholerae M66-2 7772210 YP_002809701.1 CDS VCM66_0932 NC_012578.1 998248 999168 R hypothetical protein complement(998248..999168) Vibrio cholerae M66-2 7772211 YP_002809702.1 CDS VCM66_0933 NC_012578.1 999599 1000519 R hypothetical protein complement(999599..1000519) Vibrio cholerae M66-2 7772212 YP_002809703.1 CDS VCM66_0934 NC_012578.1 1000691 1000807 R hypothetical protein complement(1000691..1000807) Vibrio cholerae M66-2 7772213 YP_002809704.1 CDS VCM66_0935 NC_012578.1 1000882 1001709 R short chain dehydrogenase complement(1000882..1001709) Vibrio cholerae M66-2 7772214 YP_002809705.1 CDS rcp NC_012578.1 1001752 1002666 R rcp protein complement(1001752..1002666) Vibrio cholerae M66-2 7772215 YP_002809706.1 CDS VCM66_0937 NC_012578.1 1003060 1003629 D phosphodiesterase 1003060..1003629 Vibrio cholerae M66-2 7772216 YP_002809707.1 CDS VCM66_0938 NC_012578.1 1003710 1004003 R selenoprotein W-like protein complement(1003710..1004003) Vibrio cholerae M66-2 7772217 YP_002809708.1 CDS toxS NC_012578.1 1004044 1004565 R regulatory protein ToxS complement(1004044..1004565) Vibrio cholerae M66-2 7772218 YP_002809709.1 CDS toxR NC_012578.1 1004575 1005459 R cholera toxin transcriptional activator complement(1004575..1005459) Vibrio cholerae M66-2 7772219 YP_002809710.1 CDS htpG NC_012578.1 1005687 1007594 D molecular chaperone; heat shock protein 90 1005687..1007594 Vibrio cholerae M66-2 7772220 YP_002809711.1 CDS adk NC_012578.1 1007929 1008573 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1007929..1008573 Vibrio cholerae M66-2 7772221 YP_002809712.1 CDS hemH NC_012578.1 1008688 1009662 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1008688..1009662 Vibrio cholerae M66-2 7772222 YP_002809713.1 CDS tppB NC_012578.1 1009762 1011306 R mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; putative tripeptide transporter permease complement(1009762..1011306) Vibrio cholerae M66-2 7772223 YP_002809714.1 CDS VCM66_0945 NC_012578.1 1011568 1011717 D hypothetical protein 1011568..1011717 Vibrio cholerae M66-2 7772224 YP_002809715.1 CDS rfaH NC_012578.1 1011751 1012248 D transcriptional activator RfaH 1011751..1012248 Vibrio cholerae M66-2 7772225 YP_002809716.1 CDS asnB NC_012578.1 1012396 1014060 R functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B complement(1012396..1014060) Vibrio cholerae M66-2 7772226 YP_002809717.1 CDS VCM66_0948 NC_012578.1 1014256 1015842 R putative glutathione-regulated potassium-efflux system protein KefB complement(1014256..1015842) Vibrio cholerae M66-2 7772227 YP_002809718.1 CDS nagC NC_012578.1 1015937 1017151 R N-acetylglucosamine repressor complement(1015937..1017151) Vibrio cholerae M66-2 7772228 YP_002809719.1 CDS nagA NC_012578.1 1017154 1018290 R catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase complement(1017154..1018290) Vibrio cholerae M66-2 7772229 YP_002809720.1 CDS nagE NC_012578.1 1018759 1020330 D PTS system N-acetylglucosamine-specific transporter subunit IIABC 1018759..1020330 Vibrio cholerae M66-2 7772230 YP_002809721.1 CDS VCM66_0952 NC_012578.1 1020459 1020560 D hypothetical protein 1020459..1020560 Vibrio cholerae M66-2 7772231 YP_002809722.1 CDS glnS NC_012578.1 1020578 1022248 D catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 1020578..1022248 Vibrio cholerae M66-2 7772232 YP_002809723.1 CDS VCM66_0954 NC_012578.1 1022413 1027278 D hypothetical protein 1022413..1027278 Vibrio cholerae M66-2 7772233 YP_002809724.1 CDS truA NC_012578.1 1027400 1028194 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1027400..1028194 Vibrio cholerae M66-2 7772234 YP_002809725.1 CDS accD NC_012578.1 1028368 1029294 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 1028368..1029294 Vibrio cholerae M66-2 7772235 YP_002809726.1 CDS folC NC_012578.1 1029339 1030604 D folylpolyglutamate synthase/dihydrofolate synthase 1029339..1030604 Vibrio cholerae M66-2 7772236 YP_002809727.1 CDS dedD NC_012578.1 1030605 1031201 D dedD protein 1030605..1031201 Vibrio cholerae M66-2 7772237 YP_002809728.1 CDS VCM66_0959 NC_012578.1 1031264 1031755 D bacteriocin production protein 1031264..1031755 Vibrio cholerae M66-2 7772238 YP_002809729.1 CDS purF NC_012578.1 1031788 1033302 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1031788..1033302 Vibrio cholerae M66-2 7772239 YP_002809730.1 CDS VCM66_0961 NC_012578.1 1033430 1034755 R hypothetical protein complement(1033430..1034755) Vibrio cholerae M66-2 7772240 YP_002809731.1 CDS rnt NC_012578.1 1034856 1035587 R Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T complement(1034856..1035587) Vibrio cholerae M66-2 7772241 YP_002809732.1 CDS VCM66_0963 NC_012578.1 1035600 1035743 R hypothetical protein complement(1035600..1035743) Vibrio cholerae M66-2 7772242 YP_002809733.1 CDS motY NC_012578.1 1035804 1036688 D sodium-type flagellar protein MotY 1035804..1036688 Vibrio cholerae M66-2 7772243 YP_002809734.1 CDS VCM66_0965 NC_012578.1 1036737 1037177 R hypothetical protein complement(1036737..1037177) Vibrio cholerae M66-2 7772244 YP_002809735.1 CDS gloA NC_012578.1 1037336 1037890 R lactoylglutathione lyase complement(1037336..1037890) Vibrio cholerae M66-2 7772245 YP_002809736.1 CDS nth NC_012578.1 1037793 1038434 R endonuclease III complement(1037793..1038434) Vibrio cholerae M66-2 7772246 YP_002809737.1 CDS VCM66_0968 NC_012578.1 1038461 1039153 R in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit complement(1038461..1039153) Vibrio cholerae M66-2 7772247 YP_002809738.1 CDS VCM66_0969 NC_012578.1 1039155 1039784 R part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG complement(1039155..1039784) Vibrio cholerae M66-2 7772248 YP_002809739.1 CDS rnfD NC_012578.1 1039796 1040842 R RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD complement(1039796..1040842) Vibrio cholerae M66-2 7772249 YP_002809740.1 CDS VCM66_0971 NC_012578.1 1040842 1043247 R part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC complement(1040842..1043247) Vibrio cholerae M66-2 7772250 YP_002809741.1 CDS VCM66_0972 NC_012578.1 1043175 1043762 R part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB complement(1043175..1043762) Vibrio cholerae M66-2 7772251 YP_002809742.1 CDS VCM66_0973 NC_012578.1 1043762 1044403 R Na(+)-translocating NADH-quinone reductase subunit E complement(1043762..1044403) Vibrio cholerae M66-2 7772252 YP_002809743.1 CDS uvrB NC_012578.1 1045225 1047255 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1045225..1047255 Vibrio cholerae M66-2 7774003 YP_002809744.1 CDS VCM66_0975 NC_012578.1 1047193 1047393 R hypothetical protein complement(1047193..1047393) Vibrio cholerae M66-2 7772254 YP_002809745.1 CDS luxO NC_012578.1 1047686 1049053 D LuxO repressor protein 1047686..1049053 Vibrio cholerae M66-2 7772255 YP_002809746.1 CDS luxU NC_012578.1 1049057 1049398 D phosphorelay protein 1049057..1049398 Vibrio cholerae M66-2 7772256 YP_002809747.1 CDS VCM66_0978 NC_012578.1 1049387 1050277 R hypothetical protein complement(1049387..1050277) Vibrio cholerae M66-2 7772257 YP_002809748.1 CDS moaA NC_012578.1 1050568 1051572 D together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 1050568..1051572 Vibrio cholerae M66-2 7772258 YP_002809749.1 CDS moaB NC_012578.1 1051632 1052144 D molybdenum cofactor biosynthesis protein B 1051632..1052144 Vibrio cholerae M66-2 7772259 YP_002809750.1 CDS moaC NC_012578.1 1052152 1052634 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 1052152..1052634 Vibrio cholerae M66-2 7772260 YP_002809751.1 CDS moaD NC_012578.1 1052631 1052876 D catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 1052631..1052876 Vibrio cholerae M66-2 7772261 YP_002809752.1 CDS moaE NC_012578.1 1052878 1053330 D molybdenum cofactor biosynthesis protein E 1052878..1053330 Vibrio cholerae M66-2 7772262 YP_002809753.1 CDS VCM66_0984 NC_012578.1 1053345 1054319 R GGDEF family protein complement(1053345..1054319) Vibrio cholerae M66-2 7772263 YP_002809754.1 CDS VCM66_0985 NC_012578.1 1054374 1054466 R hypothetical protein complement(1054374..1054466) Vibrio cholerae M66-2 7772264 YP_002809755.1 CDS VCM66_0986 NC_012578.1 1054524 1054964 D inosine monophosphate dehydrogenase-like protein 1054524..1054964 Vibrio cholerae M66-2 7772265 YP_002809756.1 CDS VCM66_0987 NC_012578.1 1054897 1055094 R hypothetical protein complement(1054897..1055094) Vibrio cholerae M66-2 7772266 YP_002809757.1 CDS zntA NC_012578.1 1055077 1057383 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 1055077..1057383 Vibrio cholerae M66-2 7772267 YP_002809758.1 CDS udp-1 NC_012578.1 1057829 1058605 D catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 1057829..1058605 Vibrio cholerae M66-2 7772268 YP_002809759.1 CDS VCM66_0990 NC_012578.1 1058678 1059571 R hypothetical protein complement(1058678..1059571) Vibrio cholerae M66-2 7772269 YP_002809760.1 CDS metG NC_012578.1 1059797 1061992 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1059797..1061992) Vibrio cholerae M66-2 7772270 YP_002809761.1 CDS mrp NC_012578.1 1061934 1063082 D mrp protein 1061934..1063082 Vibrio cholerae M66-2 7772271 YP_002809762.1 CDS udk NC_012578.1 1063241 1063900 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1063241..1063900 Vibrio cholerae M66-2 7772272 YP_002809763.1 CDS asmA NC_012578.1 1063998 1066109 D asmA protein 1063998..1066109 Vibrio cholerae M66-2 7772273 YP_002809764.1 CDS cobA NC_012578.1 1066181 1066786 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1066181..1066786) Vibrio cholerae M66-2 7772274 YP_002809765.1 CDS VCM66_0996 NC_012578.1 1066872 1067339 D phosphotyrosine protein phosphatase 1066872..1067339 Vibrio cholerae M66-2 7772275 YP_002809766.1 CDS fadL-1 NC_012578.1 1067366 1068664 R long-chain fatty acid transport protein complement(1067366..1068664) Vibrio cholerae M66-2 7772276 YP_002809767.1 CDS fadL-2 NC_012578.1 1068967 1070253 R long-chain fatty acid transport protein complement(1068967..1070253) Vibrio cholerae M66-2 7772277 YP_002809768.1 CDS VCM66_0999 NC_012578.1 1070513 1071274 R hypothetical protein complement(1070513..1071274) Vibrio cholerae M66-2 7772278 YP_002809769.1 CDS VCM66_1000 NC_012578.1 1071237 1071803 R Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor complement(1071237..1071803) Vibrio cholerae M66-2 7772279 YP_002809770.1 CDS fadI NC_012578.1 1072184 1073638 D FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 1072184..1073638 Vibrio cholerae M66-2 7772280 YP_002809771.1 CDS fadJ NC_012578.1 1073590 1075764 D multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 1073590..1075764 Vibrio cholerae M66-2 7772281 YP_002809772.1 CDS VCM66_1003 NC_012578.1 1075890 1076438 D hypothetical protein 1075890..1076438 Vibrio cholerae M66-2 7772282 YP_002809773.1 CDS VCM66_1004 NC_012578.1 1076517 1077416 R LysR family transcriptional regulator complement(1076517..1077416) Vibrio cholerae M66-2 7772283 YP_002809774.1 CDS VCM66_1005 NC_012578.1 1077625 1078731 D response regulator 1077625..1078731 Vibrio cholerae M66-2 7772284 YP_002809775.1 CDS VCM66_1006 NC_012578.1 1078901 1079032 D hypothetical protein 1078901..1079032 Vibrio cholerae M66-2 7772285 YP_002809776.1 CDS VCM66_1007 NC_012578.1 1079032 1079430 D putative Inner membrane protein 1079032..1079430 Vibrio cholerae M66-2 7772286 YP_002809777.1 CDS apt NC_012578.1 1079562 1080107 D catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1079562..1080107 Vibrio cholerae M66-2 7772287 YP_002809778.1 CDS dnaZX NC_012578.1 1080126 1082204 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 1080126..1082204 Vibrio cholerae M66-2 7772288 YP_002809779.1 CDS VCM66_1010 NC_012578.1 1082242 1082604 D hypothetical protein 1082242..1082604 Vibrio cholerae M66-2 7772289 YP_002809780.1 CDS recR NC_012578.1 1082619 1083221 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1082619..1083221 Vibrio cholerae M66-2 7772290 YP_002809781.1 CDS VCM66_1012 NC_012578.1 1083331 1083582 R putative proteinase inhibitor complement(1083331..1083582) Vibrio cholerae M66-2 7772291 YP_002809782.1 CDS VCM66_1013 NC_012578.1 1083717 1084154 D hypothetical protein 1083717..1084154 Vibrio cholerae M66-2 7772292 YP_002809783.1 CDS VCM66_1014 NC_012578.1 1084248 1084991 R short chain dehydrogenase complement(1084248..1084991) Vibrio cholerae M66-2 7772293 YP_002809784.1 CDS VCM66_1015 NC_012578.1 1085141 1086211 D SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 1085141..1086211 Vibrio cholerae M66-2 7772294 YP_002809785.1 CDS VCM66_1016 NC_012578.1 1086336 1087403 R cysteine synthase/cystathionine beta-synthase family protein complement(1086336..1087403) Vibrio cholerae M66-2 7772295 YP_002809786.1 CDS VCM66_1017 NC_012578.1 1087447 1087983 D AsnC family transcriptional regulator 1087447..1087983 Vibrio cholerae M66-2 7772296 YP_002809787.1 CDS tesB NC_012578.1 1087992 1088852 R acyl-CoA thioesterase II complement(1087992..1088852) Vibrio cholerae M66-2 7772297 YP_002809788.1 CDS VCM66_1019 NC_012578.1 1089003 1089434 D lipoprotein-like protein 1089003..1089434 Vibrio cholerae M66-2 7772298 YP_002809789.1 CDS VCM66_1020 NC_012578.1 1089488 1089790 R methylated-DNA--protein-cysteine methyltransferase-like protein complement(1089488..1089790) Vibrio cholerae M66-2 7772299 YP_002809790.1 CDS VCM66_1021 NC_012578.1 1089841 1090584 D hypothetical protein 1089841..1090584 Vibrio cholerae M66-2 7772300 YP_002809791.1 CDS VCM66_1022 NC_012578.1 1090671 1092752 D GGDEF family protein 1090671..1092752 Vibrio cholerae M66-2 7772301 YP_002809792.1 CDS VCM66_1023 NC_012578.1 1092830 1092991 D hypothetical protein 1092830..1092991 Vibrio cholerae M66-2 7772302 YP_002809793.1 CDS VCM66_1024 NC_012578.1 1093294 1093635 D ArsR family transcriptional regulator 1093294..1093635 Vibrio cholerae M66-2 7772303 YP_002809794.1 CDS gap NC_012578.1 1093732 1094733 D catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1093732..1094733 Vibrio cholerae M66-2 7772304 YP_002809795.1 CDS VCM66_1026 NC_012578.1 1094747 1095244 D putative phosphatase 1094747..1095244 Vibrio cholerae M66-2 7772305 YP_002809796.1 CDS VCM66_1027 NC_012578.1 1095283 1096518 D putative transporter 1095283..1096518 Vibrio cholerae M66-2 7772306 YP_002809797.1 CDS VCM66_1028 NC_012578.1 1096637 1096780 D hypothetical protein 1096637..1096780 Vibrio cholerae M66-2 7772307 YP_002809798.1 CDS VCM66_1029 NC_012578.1 1097082 1100348 D putative chitinase 1097082..1100348 Vibrio cholerae M66-2 7772308 YP_002809799.1 CDS VCM66_1030 NC_012578.1 1100438 1101268 R hypothetical protein complement(1100438..1101268) Vibrio cholerae M66-2 7772309 YP_002809800.1 CDS VCM66_1031 NC_012578.1 1101552 1102094 D hypothetical protein 1101552..1102094 Vibrio cholerae M66-2 7772310 YP_002809801.1 CDS VCM66_1032 NC_012578.1 1102107 1102895 D AraC family transcriptional regulator 1102107..1102895 Vibrio cholerae M66-2 7772311 YP_002809802.1 CDS VCM66_1033 NC_012578.1 1102944 1103432 R hypothetical protein complement(1102944..1103432) Vibrio cholerae M66-2 7772312 YP_002809803.1 CDS VCM66_1034 NC_012578.1 1103511 1103651 R hypothetical protein complement(1103511..1103651) Vibrio cholerae M66-2 7772313 YP_002809804.1 CDS VCM66_1035 NC_012578.1 1103696 1104685 R hypothetical protein complement(1103696..1104685) Vibrio cholerae M66-2 7772314 YP_002809805.1 CDS VCM66_1036 NC_012578.1 1104931 1105296 D Hpt family protein 1104931..1105296 Vibrio cholerae M66-2 7772315 YP_002809806.1 CDS VCM66_1037 NC_012578.1 1105293 1106435 D response regulator 1105293..1106435 Vibrio cholerae M66-2 7772316 YP_002809807.1 CDS VCM66_1038 NC_012578.1 1106470 1106835 D response regulator 1106470..1106835 Vibrio cholerae M66-2 7772317 YP_002809808.1 CDS VCM66_1039 NC_012578.1 1106832 1107416 D hypothetical protein 1106832..1107416 Vibrio cholerae M66-2 7772318 YP_002809809.1 CDS VCM66_1040 NC_012578.1 1107427 1108746 D sensory box sensor histidine kinase 1107427..1108746 Vibrio cholerae M66-2 7772319 YP_002809810.1 CDS VCM66_1042 NC_012578.1 1110063 1111673 D response regulator 1110063..1111673 Vibrio cholerae M66-2 7773957 YP_002809811.1 CDS VCM66_1043 NC_012578.1 1111690 1113033 D response regulator 1111690..1113033 Vibrio cholerae M66-2 7772321 YP_002809812.1 CDS VCM66_1044 NC_012578.1 1113062 1114666 R sensor histidine kinase complement(1113062..1114666) Vibrio cholerae M66-2 7772322 YP_002809813.1 CDS VCM66_1045 NC_012578.1 1114670 1115482 R periplasmic binding protein-like protein complement(1114670..1115482) Vibrio cholerae M66-2 7772323 YP_002809814.1 CDS VCM66_1046 NC_012578.1 1115507 1115650 R hypothetical protein complement(1115507..1115650) Vibrio cholerae M66-2 7772324 YP_002809815.1 CDS oppA NC_012578.1 1116106 1117737 D oligopeptide ABC transporter periplasmic oligopeptide-binding protein 1116106..1117737 Vibrio cholerae M66-2 7772325 YP_002809816.1 CDS oppB NC_012578.1 1117886 1118806 D oligopeptide transporter permease 1117886..1118806 Vibrio cholerae M66-2 7772326 YP_002809817.1 CDS oppC NC_012578.1 1118820 1119722 D peptide ABC transporter permease 1118820..1119722 Vibrio cholerae M66-2 7772327 YP_002809818.1 CDS oppD NC_012578.1 1119747 1120721 D oligopeptide transporter ATP-binding protein 1119747..1120721 Vibrio cholerae M66-2 7772328 YP_002809819.1 CDS oppF NC_012578.1 1120700 1121710 D oligopeptide ABC transporter ATP-binding protein 1120700..1121710 Vibrio cholerae M66-2 7772329 YP_002809820.1 CDS VCM66_1052 NC_012578.1 1121860 1122807 D hypothetical protein 1121860..1122807 Vibrio cholerae M66-2 7772330 YP_002809821.1 CDS pta NC_012578.1 1122905 1125049 R catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase complement(1122905..1125049) Vibrio cholerae M66-2 7772331 YP_002809822.1 CDS ackA-1 NC_012578.1 1125185 1126381 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1125185..1126381) Vibrio cholerae M66-2 7772332 YP_002809823.1 CDS VCM66_1055 NC_012578.1 1126728 1127186 D hypothetical protein 1126728..1127186 Vibrio cholerae M66-2 7772333 YP_002809824.1 CDS VCM66_1056 NC_012578.1 1127309 1127719 R hypothetical protein complement(1127309..1127719) Vibrio cholerae M66-2 7772334 YP_002809825.1 CDS VCM66_1057 NC_012578.1 1128157 1129122 D hypothetical protein 1128157..1129122 Vibrio cholerae M66-2 7772335 YP_002809826.1 CDS VCM66_1058 NC_012578.1 1129198 1130181 D ABC transporter permease 1129198..1130181 Vibrio cholerae M66-2 7772336 YP_002809827.1 CDS VCM66_1059 NC_012578.1 1130178 1130972 D ABC transporter ATP-binding protein 1130178..1130972 Vibrio cholerae M66-2 7772337 YP_002809828.1 CDS VCM66_1060 NC_012578.1 1131139 1132608 D GGDEF family protein 1131139..1132608 Vibrio cholerae M66-2 7772338 YP_002809829.1 CDS VCM66_1061 NC_012578.1 1132641 1133612 R hypothetical protein complement(1132641..1133612) Vibrio cholerae M66-2 7772339 YP_002809830.1 CDS VCM66_1062 NC_012578.1 1133769 1134398 D preprotein translocase SecA subunit-like protein 1133769..1134398 Vibrio cholerae M66-2 7772340 YP_002809831.1 CDS lolA NC_012578.1 1134494 1135090 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1134494..1135090 Vibrio cholerae M66-2 7772341 YP_002809832.1 CDS VCM66_1064 NC_012578.1 1135115 1136464 D recombination factor protein RarA 1135115..1136464 Vibrio cholerae M66-2 7772342 YP_002809833.1 CDS VCM66_1065 NC_012578.1 1136464 1136559 D hypothetical protein 1136464..1136559 Vibrio cholerae M66-2 7772343 YP_002809834.1 CDS serS NC_012578.1 1136568 1137875 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1136568..1137875 Vibrio cholerae M66-2 7772344 YP_002809835.1 CDS bioA NC_012578.1 1137982 1139268 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine--8-amino-7-oxononanoate transaminase complement(1137982..1139268) Vibrio cholerae M66-2 7772345 YP_002809836.1 CDS bioB NC_012578.1 1139395 1140447 D biotin synthase 1139395..1140447 Vibrio cholerae M66-2 7772346 YP_002809837.1 CDS bioF NC_012578.1 1140431 1141585 D catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 1140431..1141585 Vibrio cholerae M66-2 7772347 YP_002809838.1 CDS bioC NC_012578.1 1141447 1142385 D biotin synthesis protein BioC 1141447..1142385 Vibrio cholerae M66-2 7772348 YP_002809839.1 CDS bioD NC_012578.1 1142361 1143077 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1142361..1143077 Vibrio cholerae M66-2 7772349 YP_002809840.1 CDS VCM66_1072 NC_012578.1 1143159 1143368 R hypothetical protein complement(1143159..1143368) Vibrio cholerae M66-2 7772350 YP_002809841.1 CDS htpX NC_012578.1 1143595 1144458 D putative metalloprotease; heat shock protein HtpX 1143595..1144458 Vibrio cholerae M66-2 7772351 YP_002809842.1 CDS VCM66_1074 NC_012578.1 1144668 1145096 D putative transcriptional regulator 1144668..1145096 Vibrio cholerae M66-2 7772352 YP_002809843.1 CDS VCM66_1075 NC_012578.1 1145093 1145818 D short chain dehydrogenase 1145093..1145818 Vibrio cholerae M66-2 7772353 YP_002809844.1 CDS VCM66_1076 NC_012578.1 1145829 1147109 D hypothetical protein 1145829..1147109 Vibrio cholerae M66-2 7772354 YP_002809845.1 CDS VCM66_1077 NC_012578.1 1147109 1147918 D hypothetical protein 1147109..1147918 Vibrio cholerae M66-2 7772355 YP_002809846.1 CDS cfa NC_012578.1 1147851 1149149 D cyclopropane-fatty-acyl-phospholipid synthase 1147851..1149149 Vibrio cholerae M66-2 7772356 YP_002809847.1 CDS VCM66_1079 NC_012578.1 1149152 1149691 D hypothetical protein 1149152..1149691 Vibrio cholerae M66-2 7772357 YP_002809848.1 CDS VCM66_1080 NC_012578.1 1149624 1150190 D hypothetical protein 1149624..1150190 Vibrio cholerae M66-2 7772358 YP_002809849.1 CDS VCM66_1081 NC_012578.1 1150187 1150714 D hypothetical protein 1150187..1150714 Vibrio cholerae M66-2 7772359 YP_002809850.1 CDS purB NC_012578.1 1150805 1152175 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1150805..1152175) Vibrio cholerae M66-2 7772360 YP_002809851.1 CDS VCM66_1083 NC_012578.1 1152233 1152850 R HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein complement(1152233..1152850) Vibrio cholerae M66-2 7772361 YP_002809852.1 CDS mnmA NC_012578.1 1152873 1153991 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1152873..1153991) Vibrio cholerae M66-2 7772362 YP_002809853.1 CDS gsk-1 NC_012578.1 1154253 1155557 D inosine-guanosine kinase 1154253..1155557 Vibrio cholerae M66-2 7772363 YP_002809854.1 CDS vicH NC_012578.1 1155605 1156018 R DNA-binding protein VicH complement(1155605..1156018) Vibrio cholerae M66-2 7772364 YP_002809855.1 CDS VCM66_1087 NC_012578.1 1156706 1158307 D hypothetical protein 1156706..1158307 Vibrio cholerae M66-2 7772365 YP_002809856.1 CDS hisG NC_012578.1 1158698 1159612 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 1158698..1159612 Vibrio cholerae M66-2 7772366 YP_002809857.1 CDS hisD NC_012578.1 1159617 1160912 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1159617..1160912 Vibrio cholerae M66-2 7772367 YP_002809858.1 CDS hisC NC_012578.1 1160916 1161956 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1160916..1161956 Vibrio cholerae M66-2 7772368 YP_002809859.1 CDS hisB NC_012578.1 1162008 1163081 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 1162008..1163081 Vibrio cholerae M66-2 7772369 YP_002809860.1 CDS hisH NC_012578.1 1163081 1163692 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1163081..1163692 Vibrio cholerae M66-2 7772370 YP_002809861.1 CDS hisA NC_012578.1 1163735 1164472 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1163735..1164472 Vibrio cholerae M66-2 7772371 YP_002809862.1 CDS hisF NC_012578.1 1164454 1165227 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1164454..1165227 Vibrio cholerae M66-2 7772372 YP_002809863.1 CDS hisI NC_012578.1 1165224 1165856 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein 1165224..1165856 Vibrio cholerae M66-2 7772373 YP_002809864.1 CDS VCM66_1096 NC_012578.1 1166057 1166929 R pseudouridine synthase family 1 protein complement(1166057..1166929) Vibrio cholerae M66-2 7772374 YP_002809865.1 CDS icd NC_012578.1 1167090 1169315 D NADP-dependent isocitrate dehydrogenase 1167090..1169315 Vibrio cholerae M66-2 7772375 YP_002809866.1 CDS cspD NC_012578.1 1169414 1169644 R cold shock-like protein CspD complement(1169414..1169644) Vibrio cholerae M66-2 7772376 YP_002809867.1 CDS clpS NC_012578.1 1170108 1170428 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1170108..1170428 Vibrio cholerae M66-2 7772377 YP_002809868.1 CDS clpA NC_012578.1 1170467 1172737 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 1170467..1172737 Vibrio cholerae M66-2 7772378 YP_002809869.1 CDS VCM66_1101 NC_012578.1 1172806 1174482 R hypothetical protein complement(1172806..1174482) Vibrio cholerae M66-2 7772379 YP_002809870.1 CDS grxA NC_012578.1 1174684 1174962 R functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1 complement(1174684..1174962) Vibrio cholerae M66-2 7772380 YP_002809871.1 CDS VCM66_1103 NC_012578.1 1175235 1176503 D iron-containing alcohol dehydrogenase 1175235..1176503 Vibrio cholerae M66-2 7772381 YP_002809872.1 CDS VCM66_1104 NC_012578.1 1176594 1177448 R Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR complement(1176594..1177448) Vibrio cholerae M66-2 7772382 YP_002809873.1 CDS VCM66_1105 NC_012578.1 1177756 1179402 R putative glutamate decarboxylase complement(1177756..1179402) Vibrio cholerae M66-2 7772383 YP_002809874.1 CDS VCM66_1106 NC_012578.1 1179512 1180117 R hypothetical protein complement(1179512..1180117) Vibrio cholerae M66-2 7772384 YP_002809875.1 CDS VCM66_1107 NC_012578.1 1180210 1181115 R hypothetical protein complement(1180210..1181115) Vibrio cholerae M66-2 7772385 YP_002809876.1 CDS VCM66_1108 NC_012578.1 1181136 1182071 R hypothetical protein complement(1181136..1182071) Vibrio cholerae M66-2 7772386 YP_002809877.1 CDS VCM66_1109 NC_012578.1 1182413 1183021 D hypothetical protein 1182413..1183021 Vibrio cholerae M66-2 7772387 YP_002809878.1 CDS VCM66_1110 NC_012578.1 1183117 1183665 R hypothetical protein complement(1183117..1183665) Vibrio cholerae M66-2 7772388 YP_002809879.1 CDS VCM66_1111 NC_012578.1 1183856 1184401 R response regulator complement(1183856..1184401) Vibrio cholerae M66-2 7772389 YP_002809880.1 CDS VCM66_1112 NC_012578.1 1184350 1186305 R sensor histidine kinase complement(1184350..1186305) Vibrio cholerae M66-2 7772390 YP_002809881.1 CDS VCM66_1113 NC_012578.1 1186528 1187793 D hypothetical protein 1186528..1187793 Vibrio cholerae M66-2 7772391 YP_002809882.1 CDS serC NC_012578.1 1187870 1189009 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1187870..1189009 Vibrio cholerae M66-2 7772392 YP_002809883.1 CDS VCM66_1115 NC_012578.1 1189090 1190079 R hypothetical protein complement(1189090..1190079) Vibrio cholerae M66-2 7772393 YP_002809884.1 CDS VCM66_1116 NC_012578.1 1190079 1191587 R gonadoliberin III-like protein complement(1190079..1191587) Vibrio cholerae M66-2 7772394 YP_002809885.1 CDS VCM66_1117 NC_012578.1 1191596 1192333 R Ribosomal protein S6 modification protein complement(1191596..1192333) Vibrio cholerae M66-2 7772395 YP_002809886.1 CDS VCM66_1118 NC_012578.1 1192453 1193424 R hypothetical protein complement(1192453..1193424) Vibrio cholerae M66-2 7772396 YP_002809887.1 CDS VCM66_1119 NC_012578.1 1193536 1194276 R hypothetical protein complement(1193536..1194276) Vibrio cholerae M66-2 7772397 YP_002809888.1 CDS VCM66_1120 NC_012578.1 1194402 1195271 R hypothetical protein complement(1194402..1195271) Vibrio cholerae M66-2 7772398 YP_002809889.1 CDS aspS NC_012578.1 1195563 1197338 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1195563..1197338 Vibrio cholerae M66-2 7772399 YP_002809890.1 CDS tdk NC_012578.1 1197435 1198013 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1197435..1198013 Vibrio cholerae M66-2 7772400 YP_002809891.1 CDS gltP-1 NC_012578.1 1198115 1199491 R proton/glutamate symporter complement(1198115..1199491) Vibrio cholerae M66-2 7772401 YP_002809892.1 CDS trpA NC_012578.1 1199687 1200493 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1199687..1200493) Vibrio cholerae M66-2 7772402 YP_002809893.1 CDS trpB NC_012578.1 1200493 1201683 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1200493..1201683) Vibrio cholerae M66-2 7772403 YP_002809894.1 CDS trpC/F NC_012578.1 1201724 1203133 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1201724..1203133) Vibrio cholerae M66-2 7772404 YP_002809895.1 CDS trpD NC_012578.1 1203139 1204200 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1203139..1204200) Vibrio cholerae M66-2 7772405 YP_002809896.1 CDS trpG NC_012578.1 1204158 1204769 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1204158..1204769) Vibrio cholerae M66-2 7772406 YP_002809897.1 CDS trpE NC_012578.1 1204766 1206337 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1204766..1206337) Vibrio cholerae M66-2 7772407 YP_002809898.1 CDS VCM66_1130 NC_012578.1 1206347 1206439 R hypothetical protein complement(1206347..1206439) Vibrio cholerae M66-2 7772408 YP_002809899.1 CDS VCM66_1131 NC_012578.1 1206471 1206608 R hypothetical protein complement(1206471..1206608) Vibrio cholerae M66-2 7772409 YP_002809900.1 CDS VCM66_1132 NC_012578.1 1206673 1207545 D hypothetical protein 1206673..1207545 Vibrio cholerae M66-2 7772410 YP_002809901.1 CDS VCM66_1133 NC_012578.1 1207548 1208168 D hypothetical protein 1207548..1208168 Vibrio cholerae M66-2 7772411 YP_002809902.1 CDS VCM66_1134 NC_012578.1 1208301 1209266 D pseudouridine synthase family 1 protein 1208301..1209266 Vibrio cholerae M66-2 7772412 YP_002809903.1 CDS cydC NC_012578.1 1209434 1211155 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(1209434..1211155) Vibrio cholerae M66-2 7772413 YP_002809904.1 CDS cydD NC_012578.1 1211148 1212935 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(1211148..1212935) Vibrio cholerae M66-2 7772414 YP_002809905.1 CDS trxB NC_012578.1 1213055 1214011 R thioredoxin reductase complement(1213055..1214011) Vibrio cholerae M66-2 7772415 YP_002809906.1 CDS VCM66_1138 NC_012578.1 1214486 1215145 D hypothetical protein 1214486..1215145 Vibrio cholerae M66-2 7772416 YP_002809907.1 CDS VCM66_1139 NC_012578.1 1215120 1216370 D NifS-like protein 1215120..1216370 Vibrio cholerae M66-2 7772417 YP_002809908.1 CDS VCM66_1140 NC_012578.1 1216628 1217959 D GGDEF family protein 1216628..1217959 Vibrio cholerae M66-2 7772418 YP_002809909.1 CDS sanA NC_012578.1 1218060 1218824 R sanA protein complement(1218060..1218824) Vibrio cholerae M66-2 7772419 YP_002809910.1 CDS VCM66_1142 NC_012578.1 1218797 1219165 R hypothetical protein complement(1218797..1219165) Vibrio cholerae M66-2 7772420 YP_002809911.1 CDS sfcA NC_012578.1 1219169 1220935 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1219169..1220935) Vibrio cholerae M66-2 7772421 YP_002809912.1 CDS VCM66_1144 NC_012578.1 1221251 1221673 D hypothetical protein 1221251..1221673 Vibrio cholerae M66-2 7772422 YP_002809913.1 CDS VCM66_1145 NC_012578.1 1221875 1223092 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(1221875..1223092) Vibrio cholerae M66-2 7772423 YP_002809914.1 CDS VCM66_1146 NC_012578.1 1223147 1223545 R hypothetical protein complement(1223147..1223545) Vibrio cholerae M66-2 7772424 YP_002809915.1 CDS VCM66_1147 NC_012578.1 1223592 1223699 D hypothetical protein 1223592..1223699 Vibrio cholerae M66-2 7772425 YP_002809916.1 CDS VCM66_1148 NC_012578.1 1223837 1224034 R hypothetical protein complement(1223837..1224034) Vibrio cholerae M66-2 7772426 YP_002809917.1 CDS VCM66_1149 NC_012578.1 1224170 1225222 R hypothetical protein complement(1224170..1225222) Vibrio cholerae M66-2 7772427 YP_002809918.1 CDS VCM66_1150 NC_012578.1 1225287 1225958 R putative lipoprotein complement(1225287..1225958) Vibrio cholerae M66-2 7772428 YP_002809919.1 CDS VCM66_1151 NC_012578.1 1226058 1226747 R hypothetical protein complement(1226058..1226747) Vibrio cholerae M66-2 7772429 YP_002809920.1 CDS VCM66_1152 NC_012578.1 1226872 1227567 R hypothetical protein complement(1226872..1227567) Vibrio cholerae M66-2 7772430 YP_002809921.1 CDS VCM66_1153 NC_012578.1 1227738 1230803 D hypothetical protein 1227738..1230803 Vibrio cholerae M66-2 7772431 YP_002809922.1 CDS VCM66_1154 NC_012578.1 1230853 1231320 D hypothetical protein 1230853..1231320 Vibrio cholerae M66-2 7772432 YP_002809923.1 CDS VCM66_1155 NC_012578.1 1231570 1232781 D putative trypsin 1231570..1232781 Vibrio cholerae M66-2 7772433 YP_002809924.1 CDS VCM66_1156 NC_012578.1 1232856 1233581 R hypothetical protein complement(1232856..1233581) Vibrio cholerae M66-2 7772434 YP_002809925.1 CDS hutH NC_012578.1 1233730 1235265 R catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase complement(1233730..1235265) Vibrio cholerae M66-2 7772435 YP_002809926.1 CDS hutU NC_012578.1 1235277 1236974 R catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase complement(1235277..1236974) Vibrio cholerae M66-2 7772436 YP_002809927.1 CDS hutG NC_012578.1 1236993 1238003 R catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate; formimidoylglutamase complement(1236993..1238003) Vibrio cholerae M66-2 7772437 YP_002809928.1 CDS hutI NC_012578.1 1237993 1239201 R catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase complement(1237993..1239201) Vibrio cholerae M66-2 7772438 YP_002809929.1 CDS VCM66_1161 NC_012578.1 1239305 1240015 R histidine utilization repressor complement(1239305..1240015) Vibrio cholerae M66-2 7772439 YP_002809930.1 CDS VCM66_1162 NC_012578.1 1240132 1241079 R hypothetical protein complement(1240132..1241079) Vibrio cholerae M66-2 7772440 YP_002809931.1 CDS VCM66_1163 NC_012578.1 1241218 1241538 R highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein complement(1241218..1241538) Vibrio cholerae M66-2 7772441 YP_002809932.1 CDS VCM66_1164 NC_012578.1 1241543 1242142 R Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P complement(1241543..1242142) Vibrio cholerae M66-2 7772442 YP_002809933.1 CDS VCM66_1165 NC_012578.1 1242301 1243095 D hypothetical protein 1242301..1243095 Vibrio cholerae M66-2 7772443 YP_002809934.1 CDS VCM66_1166 NC_012578.1 1243189 1245303 D EAL family protein 1243189..1245303 Vibrio cholerae M66-2 7772444 YP_002809935.1 CDS polB NC_012578.1 1245275 1247638 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(1245275..1247638) Vibrio cholerae M66-2 7772445 YP_002809936.1 CDS VCM66_1168 NC_012578.1 1248014 1248658 D in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 1248014..1248658 Vibrio cholerae M66-2 7772446 YP_002809937.1 CDS uvrC NC_012578.1 1248658 1250490 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1248658..1250490 Vibrio cholerae M66-2 7772447 YP_002809938.1 CDS pgsA NC_012578.1 1250538 1251095 D CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1250538..1251095 Vibrio cholerae M66-2 7772448 YP_002809939.1 CDS VCM66_1171 NC_012578.1 1251988 1253106 D GGDEF family protein 1251988..1253106 Vibrio cholerae M66-2 7774027 YP_002809940.1 CDS VCM66_1172 NC_012578.1 1253103 1253588 R hypothetical protein complement(1253103..1253588) Vibrio cholerae M66-2 7772450 YP_002809941.1 CDS VCM66_1173 NC_012578.1 1253731 1253847 D hypothetical protein 1253731..1253847 Vibrio cholerae M66-2 7772451 YP_002809942.1 CDS pheS NC_012578.1 1253879 1254862 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1253879..1254862 Vibrio cholerae M66-2 7772452 YP_002809943.1 CDS pheT NC_012578.1 1254889 1257276 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1254889..1257276 Vibrio cholerae M66-2 7772453 YP_002809944.1 CDS VCM66_1176 NC_012578.1 1257559 1257693 D hypothetical protein 1257559..1257693 Vibrio cholerae M66-2 7772454 YP_002809945.1 CDS ihfA NC_012578.1 1257715 1258011 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1257715..1258011 Vibrio cholerae M66-2 7772455 YP_002809946.1 CDS VCM66_1178 NC_012578.1 1257995 1258231 R hypothetical protein complement(1257995..1258231) Vibrio cholerae M66-2 7772456 YP_002809947.1 CDS VCM66_1179 NC_012578.1 1258140 1258919 R hypothetical protein complement(1258140..1258919) Vibrio cholerae M66-2 7772457 YP_002809948.1 CDS VCM66_1180 NC_012578.1 1258991 1259236 D hypothetical protein 1258991..1259236 Vibrio cholerae M66-2 7772458 YP_002809949.1 CDS VCM66_1181 NC_012578.1 1259388 1260044 D catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide; thiopurine S-methyltransferase 1259388..1260044 Vibrio cholerae M66-2 7772459 YP_002809950.1 CDS VCM66_1182 NC_012578.1 1259997 1260167 R hypothetical protein complement(1259997..1260167) Vibrio cholerae M66-2 7772460 YP_002809951.1 CDS purT NC_012578.1 1260137 1261318 R non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 complement(1260137..1261318) Vibrio cholerae M66-2 7772461 YP_002809952.1 CDS VCM66_1184 NC_012578.1 1261466 1262341 R hypothetical protein complement(1261466..1262341) Vibrio cholerae M66-2 7772462 YP_002809953.1 CDS VCM66_1185 NC_012578.1 1262418 1262537 D hypothetical protein 1262418..1262537 Vibrio cholerae M66-2 7772463 YP_002809954.1 CDS cdd NC_012578.1 1262500 1263387 R Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase complement(1262500..1263387) Vibrio cholerae M66-2 7772464 YP_002809955.1 CDS VCM66_1187 NC_012578.1 1263557 1264231 R putative Inner membrane protein complement(1263557..1264231) Vibrio cholerae M66-2 7772465 YP_002809956.1 CDS VCM66_1188 NC_012578.1 1264222 1264611 R hypothetical protein complement(1264222..1264611) Vibrio cholerae M66-2 7772466 YP_002809957.1 CDS sbcB NC_012578.1 1264628 1266052 R Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I complement(1264628..1266052) Vibrio cholerae M66-2 7772467 YP_002809958.1 CDS VCM66_1190 NC_012578.1 1266198 1267613 R sodium/dicarboxylate symporter complement(1266198..1267613) Vibrio cholerae M66-2 7772468 YP_002809959.1 CDS VCM66_1191 NC_012578.1 1267917 1268363 D PilB-like protein 1267917..1268363 Vibrio cholerae M66-2 7772469 YP_002809960.1 CDS cobT NC_012578.1 1268890 1269999 D catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 1268890..1269999 Vibrio cholerae M66-2 7772470 YP_002809961.1 CDS cobS NC_012578.1 1269999 1270784 D catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 1269999..1270784 Vibrio cholerae M66-2 7772471 YP_002809962.1 CDS cobU NC_012578.1 1270793 1271332 D catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase 1270793..1271332 Vibrio cholerae M66-2 7772472 YP_002809963.1 CDS VCM66_1195 NC_012578.1 1271339 1271941 D putative alpha-ribazole-5`-phosphate phosphatase CobC 1271339..1271941 Vibrio cholerae M66-2 7772473 YP_002809964.1 CDS VCM66_1196 NC_012578.1 1272099 1272206 D hypothetical protein 1272099..1272206 Vibrio cholerae M66-2 7772474 YP_002809965.1 CDS astE NC_012578.1 1272257 1273285 D catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 1272257..1273285 Vibrio cholerae M66-2 7772475 YP_002809966.1 CDS VCM66_1198 NC_012578.1 1273255 1273401 R hypothetical protein complement(1273255..1273401) Vibrio cholerae M66-2 7772476 YP_002809967.1 CDS VCM66_1199 NC_012578.1 1273354 1274361 D with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 1273354..1274361 Vibrio cholerae M66-2 7772477 YP_002809968.1 CDS VCM66_1200 NC_012578.1 1274348 1275103 D ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 1274348..1275103 Vibrio cholerae M66-2 7772478 YP_002809969.1 CDS VCM66_1201 NC_012578.1 1275488 1276063 R hypothetical protein complement(1275488..1276063) Vibrio cholerae M66-2 7772479 YP_002809970.1 CDS VCM66_1202 NC_012578.1 1276242 1276637 R hypothetical protein complement(1276242..1276637) Vibrio cholerae M66-2 7772480 YP_002809971.1 CDS VCM66_1203 NC_012578.1 1276685 1278295 R methyl-accepting chemotaxis protein complement(1276685..1278295) Vibrio cholerae M66-2 7772481 YP_002809972.1 CDS VCM66_1204 NC_012578.1 1278526 1279038 R hypothetical protein complement(1278526..1279038) Vibrio cholerae M66-2 7772482 YP_002809973.1 CDS VCM66_1205 NC_012578.1 1279304 1280203 R hypothetical protein complement(1279304..1280203) Vibrio cholerae M66-2 7772483 YP_002809974.1 CDS VCM66_1206 NC_012578.1 1280216 1280314 R hypothetical protein complement(1280216..1280314) Vibrio cholerae M66-2 7772484 YP_002809975.1 CDS VCM66_1207 NC_012578.1 1280367 1281614 D putative competence damage protein CinA 1280367..1281614 Vibrio cholerae M66-2 7772485 YP_002809976.1 CDS VCM66_1208 NC_012578.1 1281787 1282215 R hypothetical protein complement(1281787..1282215) Vibrio cholerae M66-2 7772486 YP_002809977.1 CDS VCM66_1209 NC_012578.1 1282316 1282594 R putative iron-sulfur cluster-binding protein complement(1282316..1282594) Vibrio cholerae M66-2 7772487 YP_002809978.1 CDS nrdB NC_012578.1 1282594 1283763 R B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta complement(1282594..1283763) Vibrio cholerae M66-2 7772488 YP_002809979.1 CDS nrdA NC_012578.1 1283823 1286108 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(1283823..1286108) Vibrio cholerae M66-2 7772489 YP_002809980.1 CDS ubiG NC_012578.1 1286557 1287294 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(1286557..1287294) Vibrio cholerae M66-2 7772490 YP_002809981.1 CDS gyrA NC_012578.1 1287646 1290330 D DNA gyrase subunit A 1287646..1290330 Vibrio cholerae M66-2 7772491 YP_002809982.1 CDS VCM66_1214 NC_012578.1 1290543 1291541 D hypothetical protein 1290543..1291541 Vibrio cholerae M66-2 7772492 YP_002809983.1 CDS VCM66_1215 NC_012578.1 1291568 1292467 R AraC family transcriptional regulator complement(1291568..1292467) Vibrio cholerae M66-2 7772493 YP_002809984.1 CDS VCM66_1216 NC_012578.1 1292718 1293932 D Sugar efflux transporter A 1292718..1293932 Vibrio cholerae M66-2 7772494 YP_002809985.1 CDS VCM66_1217 NC_012578.1 1294115 1294291 D hypothetical protein 1294115..1294291 Vibrio cholerae M66-2 7772495 YP_002809986.1 CDS ribA NC_012578.1 1294462 1295112 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1294462..1295112 Vibrio cholerae M66-2 7772496 YP_002809987.1 CDS VCM66_1219 NC_012578.1 1295247 1296554 D putative iron-regulated protein A 1295247..1296554 Vibrio cholerae M66-2 7772497 YP_002809988.1 CDS VCM66_1220 NC_012578.1 1296761 1298146 D hypothetical protein 1296761..1298146 Vibrio cholerae M66-2 7772498 YP_002809989.1 CDS VCM66_1221 NC_012578.1 1298156 1299163 D hypothetical protein 1298156..1299163 Vibrio cholerae M66-2 7772499 YP_002809990.1 CDS VCM66_1222 NC_012578.1 1299144 1300226 D hypothetical protein 1299144..1300226 Vibrio cholerae M66-2 7772500 YP_002809991.1 CDS VCM66_1223 NC_012578.1 1300473 1302047 D hypothetical protein 1300473..1302047 Vibrio cholerae M66-2 7772501 YP_002809992.1 CDS VCM66_1224 NC_012578.1 1302193 1302741 D putative lipoprotein 1302193..1302741 Vibrio cholerae M66-2 7772502 YP_002809993.1 CDS VCM66_1225 NC_012578.1 1302805 1303461 D glyoxylase II family protein 1302805..1303461 Vibrio cholerae M66-2 7772503 YP_002809994.1 CDS VCM66_1226 NC_012578.1 1303455 1304171 R hypothetical protein complement(1303455..1304171) Vibrio cholerae M66-2 7772504 YP_002809995.1 CDS VCM66_1227 NC_012578.1 1304275 1304700 D hypothetical protein 1304275..1304700 Vibrio cholerae M66-2 7772505 YP_002809996.1 CDS VCM66_1228 NC_012578.1 1304975 1306180 D putative extracellular solute-binding protein 1304975..1306180 Vibrio cholerae M66-2 7772506 YP_002809997.1 CDS VCM66_1229 NC_012578.1 1306282 1306815 D hypothetical protein 1306282..1306815 Vibrio cholerae M66-2 7772507 YP_002809998.1 CDS VCM66_1230 NC_012578.1 1306825 1308108 D Putative TRAP transporter large permease 1306825..1308108 Vibrio cholerae M66-2 7772508 YP_002809999.1 CDS VCM66_1231 NC_012578.1 1308215 1309570 D sensor histidine kinase 1308215..1309570 Vibrio cholerae M66-2 7772509 YP_002810000.1 CDS VCM66_1232 NC_012578.1 1309551 1310201 D LuxR family transcriptional regulator 1309551..1310201 Vibrio cholerae M66-2 7772510 YP_002810001.1 CDS VCM66_1233 NC_012578.1 1310203 1310682 R MarR family transcriptional regulator complement(1310203..1310682) Vibrio cholerae M66-2 7772511 YP_002810002.1 CDS VCM66_1234 NC_012578.1 1311039 1312661 D transporter, BCCT family 1311039..1312661 Vibrio cholerae M66-2 7772512 YP_002810003.1 CDS VCM66_1235 NC_012578.1 1312826 1314121 R hypothetical protein complement(1312826..1314121) Vibrio cholerae M66-2 7772513 YP_002810004.1 CDS celA NC_012578.1 1314364 1314669 D PTS system cellobiose-specific transporter subunit IIB 1314364..1314669 Vibrio cholerae M66-2 7772514 YP_002810005.1 CDS celB NC_012578.1 1314748 1316088 D PTS system cellobiose-specific transporter subunit IIC 1314748..1316088 Vibrio cholerae M66-2 7772515 YP_002810006.1 CDS celC NC_012578.1 1316135 1316470 D PTS system cellobiose-specific transporter subunit IIA 1316135..1316470 Vibrio cholerae M66-2 7772516 YP_002810007.1 CDS celF NC_012578.1 1316452 1317774 D 6-phospho-beta-glucosidase 1316452..1317774 Vibrio cholerae M66-2 7772517 YP_002810008.1 CDS VCM66_1240 NC_012578.1 1317797 1318555 D hypothetical protein 1317797..1318555 Vibrio cholerae M66-2 7772518 YP_002810009.1 CDS VCM66_1241 NC_012578.1 1318656 1319678 D LacI family transcriptional regulator 1318656..1319678 Vibrio cholerae M66-2 7772519 YP_002810010.1 CDS mdoG NC_012578.1 1322009 1323646 R involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G complement(1322009..1323646) Vibrio cholerae M66-2 7773958 YP_002810011.1 CDS VCM66_1244 NC_012578.1 1324039 1325934 D methyl-accepting chemotaxis protein 1324039..1325934 Vibrio cholerae M66-2 7772521 YP_002810012.1 CDS VCM66_1245 NC_012578.1 1326073 1326783 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(1326073..1326783) Vibrio cholerae M66-2 7772522 YP_002810013.1 CDS VCM66_1246 NC_012578.1 1326780 1328504 R hypothetical protein complement(1326780..1328504) Vibrio cholerae M66-2 7772523 YP_002810014.1 CDS VCM66_1247 NC_012578.1 1328907 1329008 D hypothetical protein 1328907..1329008 Vibrio cholerae M66-2 7772524 YP_002810015.1 CDS aspC NC_012578.1 1328973 1330214 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1328973..1330214) Vibrio cholerae M66-2 7772525 YP_002810016.1 CDS VCM66_1249 NC_012578.1 1330375 1330560 R hypothetical protein complement(1330375..1330560) Vibrio cholerae M66-2 7772526 YP_002810017.1 CDS VCM66_1250 NC_012578.1 1330532 1332010 R hypothetical protein complement(1330532..1332010) Vibrio cholerae M66-2 7772527 YP_002810018.1 CDS thiD NC_012578.1 1332519 1333367 D catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 1332519..1333367 Vibrio cholerae M66-2 7772528 YP_002810019.1 CDS asnC NC_012578.1 1333433 1334878 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1333433..1334878) Vibrio cholerae M66-2 7772529 YP_002810020.1 CDS VCM66_1253 NC_012578.1 1334980 1336611 R methyl-accepting chemotaxis protein complement(1334980..1336611) Vibrio cholerae M66-2 7772530 YP_002810021.1 CDS VCM66_1254 NC_012578.1 1337009 1337377 D 6-pyruvoyl tetrahydrobiopterin synthase 1337009..1337377 Vibrio cholerae M66-2 7772531 YP_002810022.1 CDS sdaA-1 NC_012578.1 1337466 1338827 R L-serine dehydratase complement(1337466..1338827) Vibrio cholerae M66-2 7772532 YP_002810023.1 CDS sdaC-1 NC_012578.1 1338920 1340173 R serine transporter complement(1338920..1340173) Vibrio cholerae M66-2 7772533 YP_002810024.1 CDS VCM66_1257 NC_012578.1 1340472 1341086 R MutT/nudix family protein complement(1340472..1341086) Vibrio cholerae M66-2 7772534 YP_002810025.1 CDS pabB NC_012578.1 1341283 1342659 R para-aminobenzoate synthase, component I complement(1341283..1342659) Vibrio cholerae M66-2 7772535 YP_002810026.1 CDS VCM66_1259 NC_012578.1 1342835 1344352 D putative fumarate hydratase, class I 1342835..1344352 Vibrio cholerae M66-2 7772536 YP_002810027.1 CDS VCM66_1260 NC_012578.1 1344501 1344686 D hypothetical protein 1344501..1344686 Vibrio cholerae M66-2 7772537 YP_002810028.1 CDS VCM66_1261 NC_012578.1 1344911 1346284 D hypothetical protein 1344911..1346284 Vibrio cholerae M66-2 7772538 YP_002810029.1 CDS VCM66_1262 NC_012578.1 1346281 1347300 D hypothetical protein 1346281..1347300 Vibrio cholerae M66-2 7772539 YP_002810030.1 CDS tyrR NC_012578.1 1347414 1348955 D transcriptional regulator TyrR 1347414..1348955 Vibrio cholerae M66-2 7772540 YP_002810031.1 CDS rimJ NC_012578.1 1348955 1349530 D ribosomal-protein-alanine acetyltransferase 1348955..1349530 Vibrio cholerae M66-2 7772541 YP_002810032.1 CDS VCM66_1265 NC_012578.1 1349625 1350098 D hypothetical protein 1349625..1350098 Vibrio cholerae M66-2 7772542 YP_002810033.1 CDS VCM66_1266 NC_012578.1 1350166 1351044 R putative Inner membrane protein complement(1350166..1351044) Vibrio cholerae M66-2 7772543 YP_002810034.1 CDS VCM66_1267 NC_012578.1 1351165 1352451 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(1351165..1352451) Vibrio cholerae M66-2 7772544 YP_002810035.1 CDS VCM66_1268 NC_012578.1 1352500 1354131 R methyl-accepting chemotaxis protein complement(1352500..1354131) Vibrio cholerae M66-2 7772545 YP_002810036.1 CDS VCM66_1269 NC_012578.1 1354465 1355928 D putative transporter 1354465..1355928 Vibrio cholerae M66-2 7772546 YP_002810037.1 CDS VCM66_1270 NC_012578.1 1355938 1357287 D sensor histidine kinase 1355938..1357287 Vibrio cholerae M66-2 7772547 YP_002810038.1 CDS VCM66_1271 NC_012578.1 1357256 1357732 D putative chemotaxis protein CheY 1357256..1357732 Vibrio cholerae M66-2 7772548 YP_002810039.1 CDS VCM66_1272 NC_012578.1 1357760 1358680 R hypothetical protein complement(1357760..1358680) Vibrio cholerae M66-2 7772549 YP_002810040.1 CDS ompV NC_012578.1 1358778 1359551 R outer membrane protein OmpV complement(1358778..1359551) Vibrio cholerae M66-2 7772550 YP_002810041.1 CDS VCM66_1274 NC_012578.1 1359764 1361086 R sensor histidine kinase complement(1359764..1361086) Vibrio cholerae M66-2 7772551 YP_002810042.1 CDS VCM66_1275 NC_012578.1 1361112 1361816 R DNA-binding response regulator complement(1361112..1361816) Vibrio cholerae M66-2 7772552 YP_002810043.1 CDS VCM66_1276 NC_012578.1 1362192 1365263 D hypothetical protein 1362192..1365263 Vibrio cholerae M66-2 7772553 YP_002810044.1 CDS VCM66_1277 NC_012578.1 1365344 1365559 R hypothetical protein complement(1365344..1365559) Vibrio cholerae M66-2 7772554 YP_002810045.1 CDS VCM66_1278 NC_012578.1 1365538 1366020 R hypothetical protein complement(1365538..1366020) Vibrio cholerae M66-2 7772555 YP_002810046.1 CDS VCM66_1279 NC_012578.1 1366385 1366573 R hypothetical protein complement(1366385..1366573) Vibrio cholerae M66-2 7772556 YP_002810047.1 CDS mglB NC_012578.1 1366519 1367493 D galactoside ABC transporter periplasmic D-galactose/D-glucose-binding protein 1366519..1367493 Vibrio cholerae M66-2 7772557 YP_002810048.1 CDS VCM66_1281 NC_012578.1 1367561 1367716 R hypothetical protein complement(1367561..1367716) Vibrio cholerae M66-2 7772558 YP_002810049.1 CDS mglA NC_012578.1 1367663 1369207 D with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 1367663..1369207 Vibrio cholerae M66-2 7772559 YP_002810050.1 CDS mglC NC_012578.1 1369212 1370225 D ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane component 1369212..1370225 Vibrio cholerae M66-2 7772560 YP_002810051.1 CDS VCM66_1284 NC_012578.1 1370635 1371273 D opacity protein-like protein 1370635..1371273 Vibrio cholerae M66-2 7772561 YP_002810052.1 CDS VCM66_1285 NC_012578.1 1371594 1372421 D hypothetical protein 1371594..1372421 Vibrio cholerae M66-2 7772562 YP_002810053.1 CDS VCM66_1286 NC_012578.1 1372429 1372557 R hypothetical protein complement(1372429..1372557) Vibrio cholerae M66-2 7772563 YP_002810054.1 CDS VCM66_1287 NC_012578.1 1372572 1374101 R hypothetical protein complement(1372572..1374101) Vibrio cholerae M66-2 7772564 YP_002810055.1 CDS VCM66_1288 NC_012578.1 1374111 1374662 R hypothetical protein complement(1374111..1374662) Vibrio cholerae M66-2 7772565 YP_002810056.1 CDS VCM66_1289 NC_012578.1 1374860 1375831 R hypothetical protein complement(1374860..1375831) Vibrio cholerae M66-2 7772566 YP_002810057.1 CDS VCM66_1290 NC_012578.1 1376461 1377168 D GntR family transcriptional regulator 1376461..1377168 Vibrio cholerae M66-2 7772567 YP_002810058.1 CDS prpB NC_012578.1 1377149 1378075 D catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 1377149..1378075 Vibrio cholerae M66-2 7772568 YP_002810059.1 CDS prpC NC_012578.1 1378251 1379384 D catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 1378251..1379384 Vibrio cholerae M66-2 7772569 YP_002810060.1 CDS acnA NC_012578.1 1379480 1382086 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1379480..1382086 Vibrio cholerae M66-2 7772570 YP_002810061.1 CDS VCM66_1294 NC_012578.1 1382095 1383297 D hypothetical protein 1382095..1383297 Vibrio cholerae M66-2 7772571 YP_002810062.1 CDS prpE NC_012578.1 1383281 1385179 D prpE protein 1383281..1385179 Vibrio cholerae M66-2 7772572 YP_002810063.1 CDS VCM66_1296 NC_012578.1 1385353 1385829 D putative acetyltransferase 1385353..1385829 Vibrio cholerae M66-2 7772573 YP_002810064.1 CDS VCM66_1297 NC_012578.1 1385910 1387307 D MutT/nudix family protein 1385910..1387307 Vibrio cholerae M66-2 7772574 YP_002810065.1 CDS VCM66_1298 NC_012578.1 1387373 1388479 R peptidase, M20A family complement(1387373..1388479) Vibrio cholerae M66-2 7772575 YP_002810066.1 CDS hppD NC_012578.1 1388903 1390012 D 4-hydroxyphenylpyruvate dioxygenase 1388903..1390012 Vibrio cholerae M66-2 7772576 YP_002810067.1 CDS VCM66_1300 NC_012578.1 1390005 1391141 D putative oxidoreductase 1390005..1391141 Vibrio cholerae M66-2 7772577 YP_002810068.1 CDS VCM66_1301 NC_012578.1 1391148 1392167 D hypothetical protein 1391148..1392167 Vibrio cholerae M66-2 7772578 YP_002810069.1 CDS maiA NC_012578.1 1392164 1392811 D maleylacetoacetate isomerase 1392164..1392811 Vibrio cholerae M66-2 7772579 YP_002810070.1 CDS VCM66_1303 NC_012578.1 1392793 1394118 R response regulator complement(1392793..1394118) Vibrio cholerae M66-2 7772580 YP_002810071.1 CDS VCM66_1304 NC_012578.1 1394054 1398049 D sensory box sensor histidine kinase/response regulator 1394054..1398049 Vibrio cholerae M66-2 7772581 YP_002810072.1 CDS VCM66_1305 NC_012578.1 1398155 1398628 R putative antioxidant complement(1398155..1398628) Vibrio cholerae M66-2 7772582 YP_002810073.1 CDS VCM66_1306 NC_012578.1 1398842 1399036 R hypothetical protein complement(1398842..1399036) Vibrio cholerae M66-2 7772583 YP_002810074.1 CDS VCM66_1307 NC_012578.1 1399049 1399141 D hypothetical protein 1399049..1399141 Vibrio cholerae M66-2 7772584 YP_002810075.1 CDS VCM66_1308 NC_012578.1 1399279 1402209 D GGDEF family protein 1399279..1402209 Vibrio cholerae M66-2 7772585 YP_002810076.1 CDS VCM66_1309 NC_012578.1 1402251 1403507 R hypothetical protein complement(1402251..1403507) Vibrio cholerae M66-2 7772586 YP_002810077.1 CDS VCM66_1310 NC_012578.1 1403681 1403965 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1403681..1403965 Vibrio cholerae M66-2 7772587 YP_002810078.1 CDS VCM66_1311 NC_012578.1 1404031 1404360 R sulfite reductase subunit gamma-like protein complement(1404031..1404360) Vibrio cholerae M66-2 7772588 YP_002810079.1 CDS VCM66_1312 NC_012578.1 1404326 1404445 R hypothetical protein complement(1404326..1404445) Vibrio cholerae M66-2 7772589 YP_002810080.1 CDS VCM66_1313 NC_012578.1 1404474 1405145 R hypothetical protein complement(1404474..1405145) Vibrio cholerae M66-2 7772590 YP_002810081.1 CDS VCM66_1314 NC_012578.1 1405390 1406145 R amino acid ABC transporter ATP-binding protein complement(1405390..1406145) Vibrio cholerae M66-2 7772591 YP_002810082.1 CDS VCM66_1315 NC_012578.1 1406168 1407265 R amino acid ABC transporter permease complement(1406168..1407265) Vibrio cholerae M66-2 7772592 YP_002810083.1 CDS VCM66_1316 NC_012578.1 1407268 1408473 R amino acid ABC transporter permease complement(1407268..1408473) Vibrio cholerae M66-2 7772593 YP_002810084.1 CDS VCM66_1317 NC_012578.1 1408599 1409627 R amino acid ABC transporter substrate-binding protein complement(1408599..1409627) Vibrio cholerae M66-2 7772594 YP_002810085.1 CDS VCM66_1318 NC_012578.1 1410082 1411020 D siroheme synthase component protein 1410082..1411020 Vibrio cholerae M66-2 7772595 YP_002810086.1 CDS VCM66_1319 NC_012578.1 1411086 1411907 R putative phosphatase complement(1411086..1411907) Vibrio cholerae M66-2 7772596 YP_002810087.1 CDS VCM66_1320 NC_012578.1 1412183 1412920 D hypothetical protein 1412183..1412920 Vibrio cholerae M66-2 7772597 YP_002810088.1 CDS exsB NC_012578.1 1412933 1413628 D YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 1412933..1413628 Vibrio cholerae M66-2 7772598 YP_002810089.1 CDS VCM66_1322 NC_012578.1 1413600 1415603 R GGDEF family protein complement(1413600..1415603) Vibrio cholerae M66-2 7772599 YP_002810090.1 CDS VCM66_1323 NC_012578.1 1415774 1416022 D hypothetical protein 1415774..1416022 Vibrio cholerae M66-2 7772600 YP_002810091.1 CDS VCM66_1324 NC_012578.1 1416179 1417195 D hypothetical protein 1416179..1417195 Vibrio cholerae M66-2 7772601 YP_002810092.1 CDS VCM66_1325 NC_012578.1 1417192 1418523 D GGDEF family protein 1417192..1418523 Vibrio cholerae M66-2 7772602 YP_002810093.1 CDS VCM66_1326 NC_012578.1 1418574 1419254 R hypothetical protein complement(1418574..1419254) Vibrio cholerae M66-2 7772603 YP_002810094.1 CDS VCM66_1327 NC_012578.1 1419628 1420806 D GGDEF family protein 1419628..1420806 Vibrio cholerae M66-2 7772604 YP_002810095.1 CDS VCM66_1328 NC_012578.1 1420918 1423764 R DnaK-like protein complement(1420918..1423764) Vibrio cholerae M66-2 7772605 YP_002810096.1 CDS VCM66_1329 NC_012578.1 1423806 1425701 R DnaK-like protein complement(1423806..1425701) Vibrio cholerae M66-2 7772606 YP_002810097.1 CDS VCM66_1330 NC_012578.1 1425701 1426429 R hypothetical protein complement(1425701..1426429) Vibrio cholerae M66-2 7772607 YP_002810098.1 CDS VCM66_1331 NC_012578.1 1426841 1428454 D GGDEF family protein 1426841..1428454 Vibrio cholerae M66-2 7772608 YP_002810099.1 CDS VCM66_1332 NC_012578.1 1428472 1429002 D hypothetical protein 1428472..1429002 Vibrio cholerae M66-2 7772609 YP_002810100.1 CDS VCM66_1333 NC_012578.1 1429004 1429186 D hypothetical protein 1429004..1429186 Vibrio cholerae M66-2 7772610 YP_002810101.1 CDS VCM66_1334 NC_012578.1 1429288 1429752 R hypothetical protein complement(1429288..1429752) Vibrio cholerae M66-2 7772611 YP_002810102.1 CDS VCM66_1335 NC_012578.1 1429799 1430149 R hypothetical protein complement(1429799..1430149) Vibrio cholerae M66-2 7772612 YP_002810103.1 CDS VCM66_1336 NC_012578.1 1430184 1430393 R hypothetical protein complement(1430184..1430393) Vibrio cholerae M66-2 7772613 YP_002810104.1 CDS hrpA NC_012578.1 1430351 1434280 D involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1430351..1434280 Vibrio cholerae M66-2 7772614 YP_002810105.1 CDS VCM66_1338 NC_012578.1 1434258 1434389 R hypothetical protein complement(1434258..1434389) Vibrio cholerae M66-2 7772615 YP_002810106.1 CDS VCM66_1339 NC_012578.1 1434420 1434902 D hypothetical protein 1434420..1434902 Vibrio cholerae M66-2 7772616 YP_002810107.1 CDS VCM66_1340 NC_012578.1 1434935 1435045 R hypothetical protein complement(1434935..1435045) Vibrio cholerae M66-2 7772617 YP_002810108.1 CDS VCM66_1341 NC_012578.1 1435119 1436471 D putative chaperone 1435119..1436471 Vibrio cholerae M66-2 7772618 YP_002810109.1 CDS VCM66_1342 NC_012578.1 1436505 1436603 D hypothetical protein 1436505..1436603 Vibrio cholerae M66-2 7772619 YP_002810110.1 CDS lplA NC_012578.1 1436596 1437612 D Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 1436596..1437612 Vibrio cholerae M66-2 7772620 YP_002810111.1 CDS VCM66_1344 NC_012578.1 1437848 1438027 D hypothetical protein 1437848..1438027 Vibrio cholerae M66-2 7772621 YP_002810112.1 CDS VCM66_1345 NC_012578.1 1438005 1438955 R LysR family transcriptional regulator complement(1438005..1438955) Vibrio cholerae M66-2 7772622 YP_002810113.1 CDS VCM66_1346 NC_012578.1 1439042 1440448 D putative multidrug transporter 1439042..1440448 Vibrio cholerae M66-2 7772623 YP_002810114.1 CDS VCM66_1347 NC_012578.1 1440604 1442118 D putative deoxyribodipyrimidine photolyase 1440604..1442118 Vibrio cholerae M66-2 7772624 YP_002810115.1 CDS sugE NC_012578.1 1442264 1442578 D sugE protein 1442264..1442578 Vibrio cholerae M66-2 7772625 YP_002810116.1 CDS VCM66_1349 NC_012578.1 1442633 1443868 R methyl-accepting chemotaxis protein complement(1442633..1443868) Vibrio cholerae M66-2 7772626 YP_002810117.1 CDS cheY-1 NC_012578.1 1443876 1444256 R chemotaxis protein CheY complement(1443876..1444256) Vibrio cholerae M66-2 7772627 YP_002810118.1 CDS VCM66_1351 NC_012578.1 1444249 1444509 R hypothetical protein complement(1444249..1444509) Vibrio cholerae M66-2 7772628 YP_002810119.1 CDS cheA-1 NC_012578.1 1444499 1446784 R chemotaxis protein CheA complement(1444499..1446784) Vibrio cholerae M66-2 7772629 YP_002810120.1 CDS cheY-2 NC_012578.1 1446781 1447155 R chemotaxis protein CheY complement(1446781..1447155) Vibrio cholerae M66-2 7772630 YP_002810121.1 CDS cheR-1 NC_012578.1 1447152 1447997 R chemotaxis protein methyltransferase CheR complement(1447152..1447997) Vibrio cholerae M66-2 7772631 YP_002810122.1 CDS VCM66_1355 NC_012578.1 1448008 1448664 R hypothetical protein complement(1448008..1448664) Vibrio cholerae M66-2 7772632 YP_002810123.1 CDS cheB-1 NC_012578.1 1448651 1449727 R protein-glutamate methylesterase CheB complement(1448651..1449727) Vibrio cholerae M66-2 7772633 YP_002810124.1 CDS VCM66_1357 NC_012578.1 1449748 1451310 R putative purine-binding chemotaxis protein Chew complement(1449748..1451310) Vibrio cholerae M66-2 7772634 YP_002810125.1 CDS VCM66_1358 NC_012578.1 1451323 1453248 R methyl-accepting chemotaxis protein complement(1451323..1453248) Vibrio cholerae M66-2 7772635 YP_002810126.1 CDS VCM66_1359 NC_012578.1 1453382 1453504 R hypothetical protein complement(1453382..1453504) Vibrio cholerae M66-2 7772636 YP_002810127.1 CDS VCM66_1360 NC_012578.1 1453744 1455531 D methyl-accepting chemotaxis protein 1453744..1455531 Vibrio cholerae M66-2 7772637 YP_002810128.1 CDS VCM66_1361 NC_012578.1 1455610 1456926 D methyl-accepting chemotaxis protein 1455610..1456926 Vibrio cholerae M66-2 7772638 YP_002810129.1 CDS rhlE-1 NC_012578.1 1457108 1458301 D ATP-dependent RNA helicase RhlE 1457108..1458301 Vibrio cholerae M66-2 7772639 YP_002810130.1 CDS VCM66_1363 NC_012578.1 1458360 1458962 R TetR family transcriptional regulator complement(1458360..1458962) Vibrio cholerae M66-2 7772640 YP_002810131.1 CDS VCM66_1364 NC_012578.1 1459069 1460523 D putative multidrug resistance protein 1459069..1460523 Vibrio cholerae M66-2 7772641 YP_002810132.1 CDS vceA NC_012578.1 1460504 1461724 D multidrug resistance protein VceA 1460504..1461724 Vibrio cholerae M66-2 7772642 YP_002810133.1 CDS vceB NC_012578.1 1461734 1463269 D multidrug resistance protein VceB 1461734..1463269 Vibrio cholerae M66-2 7772643 YP_002810134.1 CDS VCM66_1367 NC_012578.1 1463223 1463339 D hypothetical protein 1463223..1463339 Vibrio cholerae M66-2 7772644 YP_002810135.1 CDS VCM66_1368 NC_012578.1 1463344 1465080 R methyl-accepting chemotaxis protein complement(1463344..1465080) Vibrio cholerae M66-2 7772645 YP_002810136.1 CDS VCM66_1369 NC_012578.1 1465302 1466876 R thermostable carboxypeptidase 1 complement(1465302..1466876) Vibrio cholerae M66-2 7772646 YP_002810137.1 CDS hcp-1 NC_012578.1 1467074 1467592 D hcp protein 1467074..1467592 Vibrio cholerae M66-2 7772647 YP_002810138.1 CDS vgrG-1 NC_012578.1 1467720 1471211 D vgrG protein 1467720..1471211 Vibrio cholerae M66-2 7772648 YP_002810139.1 CDS VCM66_1372 NC_012578.1 1471190 1472050 D hypothetical protein 1471190..1472050 Vibrio cholerae M66-2 7772649 YP_002810140.1 CDS VCM66_1373 NC_012578.1 1472053 1473978 D hypothetical protein 1472053..1473978 Vibrio cholerae M66-2 7772650 YP_002810141.1 CDS VCM66_1374 NC_012578.1 1473975 1474718 D hypothetical protein 1473975..1474718 Vibrio cholerae M66-2 7772651 YP_002810142.1 CDS VCM66_1375 NC_012578.1 1474863 1475600 D hypothetical protein 1474863..1475600 Vibrio cholerae M66-2 7772652 YP_002810143.1 CDS VCM66_1376 NC_012578.1 1475688 1476326 D hypothetical protein 1475688..1476326 Vibrio cholerae M66-2 7772653 YP_002810144.1 CDS VCM66_1377 NC_012578.1 1476399 1477775 R sodium/alanine symporter complement(1476399..1477775) Vibrio cholerae M66-2 7772654 YP_002810145.1 CDS VCM66_1378 NC_012578.1 1478278 1478436 D hypothetical protein 1478278..1478436 Vibrio cholerae M66-2 7772655 YP_002810146.1 CDS VCM66_1379 NC_012578.1 1478453 1479187 D hypothetical protein 1478453..1479187 Vibrio cholerae M66-2 7772656 YP_002810147.1 CDS potD-1 NC_012578.1 1479334 1480371 R spermidine/putrescine ABC transporter substrate-binding protein complement(1479334..1480371) Vibrio cholerae M66-2 7772657 YP_002810148.1 CDS potD-2 NC_012578.1 1480483 1481583 R spermidine/putrescine ABC transporter substrate-binding protein complement(1480483..1481583) Vibrio cholerae M66-2 7772658 YP_002810149.1 CDS potC NC_012578.1 1481617 1482387 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1481617..1482387) Vibrio cholerae M66-2 7772659 YP_002810150.1 CDS potB NC_012578.1 1482387 1483247 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1482387..1483247) Vibrio cholerae M66-2 7772660 YP_002810151.1 CDS potA NC_012578.1 1483228 1484361 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase protein complement(1483228..1484361) Vibrio cholerae M66-2 7772661 YP_002810152.1 CDS VCM66_1385 NC_012578.1 1484647 1485492 D hypothetical protein 1484647..1485492 Vibrio cholerae M66-2 7772662 YP_002810153.1 CDS VCM66_1386 NC_012578.1 1485482 1486285 D putative bax protein 1485482..1486285 Vibrio cholerae M66-2 7772663 YP_002810154.1 CDS VCM66_1387 NC_012578.1 1486287 1486946 D hypothetical protein 1486287..1486946 Vibrio cholerae M66-2 7772664 YP_002810155.1 CDS VCM66_1388 NC_012578.1 1487023 1487955 R hypothetical protein complement(1487023..1487955) Vibrio cholerae M66-2 7772665 YP_002810156.1 CDS VCM66_1389 NC_012578.1 1488082 1489029 R with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE complement(1488082..1489029) Vibrio cholerae M66-2 7772666 YP_002810157.1 CDS fnr NC_012578.1 1489159 1489911 R Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator complement(1489159..1489911) Vibrio cholerae M66-2 7772667 YP_002810158.1 CDS VCM66_1391 NC_012578.1 1490001 1490675 R hypothetical protein complement(1490001..1490675) Vibrio cholerae M66-2 7772668 YP_002810159.1 CDS VCM66_1392 NC_012578.1 1490672 1490836 R FixS-like protein complement(1490672..1490836) Vibrio cholerae M66-2 7772669 YP_002810160.1 CDS VCM66_1393 NC_012578.1 1490840 1493212 R cation transport ATPase, E1-E2 family complement(1490840..1493212) Vibrio cholerae M66-2 7772670 YP_002810161.1 CDS VCM66_1394 NC_012578.1 1493217 1493693 R hypothetical protein complement(1493217..1493693) Vibrio cholerae M66-2 7772671 YP_002810162.1 CDS ccoP NC_012578.1 1493772 1494752 R cytochrome c oxidase subunit CcoP complement(1493772..1494752) Vibrio cholerae M66-2 7772672 YP_002810163.1 CDS ccoQ NC_012578.1 1494760 1494924 R cytochrome c oxidase subunit CcoQ complement(1494760..1494924) Vibrio cholerae M66-2 7772673 YP_002810164.1 CDS ccoO NC_012578.1 1494936 1495556 R CcoO; FixO; cbb3-type cytochrome c oxidase subunit II complement(1494936..1495556) Vibrio cholerae M66-2 7772674 YP_002810165.1 CDS ccoN NC_012578.1 1495570 1497003 R CcoN; FixN; cbb3-type cytochrome c oxidase subunit I complement(1495570..1497003) Vibrio cholerae M66-2 7772675 YP_002810166.1 CDS VCM66_1399 NC_012578.1 1497232 1497612 D hypothetical protein 1497232..1497612 Vibrio cholerae M66-2 7772676 YP_002810167.1 CDS VCM66_1400 NC_012578.1 1497681 1498898 D hypothetical protein 1497681..1498898 Vibrio cholerae M66-2 7772677 YP_002810168.1 CDS VCM66_1401 NC_012578.1 1498895 1500613 D sensor histidine kinase/response regulator 1498895..1500613 Vibrio cholerae M66-2 7772678 YP_002810169.1 CDS VCM66_1402 NC_012578.1 1500674 1502839 R putative toxin secretion transporter complement(1500674..1502839) Vibrio cholerae M66-2 7772679 YP_002810170.1 CDS rtxD NC_012578.1 1502842 1504245 R RTX toxin transporter complement(1502842..1504245) Vibrio cholerae M66-2 7772680 YP_002810171.1 CDS rtxB NC_012578.1 1504200 1506362 R RTX toxin transporter complement(1504200..1506362) Vibrio cholerae M66-2 7772681 YP_002810172.1 CDS VCM66_1405 NC_012578.1 1506720 1507079 D hypothetical protein 1506720..1507079 Vibrio cholerae M66-2 7772682 YP_002810173.1 CDS VCM66_1406 NC_012578.1 1507105 1507566 D RTX toxin activating protein 1507105..1507566 Vibrio cholerae M66-2 7772683 YP_002810174.1 CDS rtxA NC_012578.1 1507551 1521227 D RTX toxin RtxA 1507551..1521227 Vibrio cholerae M66-2 7772684 YP_002810175.1 CDS VCM66_1408 NC_012578.1 1521573 1522157 R hypothetical protein complement(1521573..1522157) Vibrio cholerae M66-2 7772685 YP_002810176.1 CDS VCM66_1409 NC_012578.1 1522150 1522317 R hypothetical protein complement(1522150..1522317) Vibrio cholerae M66-2 7772686 YP_002810177.1 CDS VCM66_1410 NC_012578.1 1522395 1523087 R hypothetical protein complement(1522395..1523087) Vibrio cholerae M66-2 7772687 YP_002810178.1 CDS VCM66_1411 NC_012578.1 1523217 1523501 R hypothetical protein complement(1523217..1523501) Vibrio cholerae M66-2 7772688 YP_002810179.1 CDS cri-1 NC_012578.1 1523506 1525074 R phage replication protein Cri complement(1523506..1525074) Vibrio cholerae M66-2 7772689 YP_002810180.1 CDS tlcR NC_012578.1 1525236 1525802 D tlcR protein 1525236..1525802 Vibrio cholerae M66-2 7772690 YP_002810181.1 CDS VCM66_1414 NC_012578.1 1526841 1527008 R hypothetical protein complement(1526841..1527008) Vibrio cholerae M66-2 7772691 YP_002810182.1 CDS VCM66_1415 NC_012578.1 1527001 1527168 R hypothetical protein complement(1527001..1527168) Vibrio cholerae M66-2 7772692 YP_002810183.1 CDS VCM66_1416 NC_012578.1 1527246 1527938 R hypothetical protein complement(1527246..1527938) Vibrio cholerae M66-2 7772693 YP_002810184.1 CDS VCM66_1417 NC_012578.1 1528068 1528352 R hypothetical protein complement(1528068..1528352) Vibrio cholerae M66-2 7772694 YP_002810185.1 CDS cri-2 NC_012578.1 1528357 1529925 R phage replication protein Cri complement(1528357..1529925) Vibrio cholerae M66-2 7772695 YP_002810186.1 CDS tlcR NC_012578.1 1530087 1530653 D tlcR protein 1530087..1530653 Vibrio cholerae M66-2 7772696 YP_002810187.1 CDS VCM66_1420 NC_012578.1 1530962 1531315 D ISVch4 transposase, OrfA 1530962..1531315 Vibrio cholerae M66-2 7772697 YP_002810188.1 CDS VCM66_1421 NC_012578.1 1531312 1532184 D ISVch4 transposase, OrfB 1531312..1532184 Vibrio cholerae M66-2 7772698 YP_002810189.1 CDS VCM66_1422 NC_012578.1 1533093 1533452 R hypothetical protein complement(1533093..1533452) Vibrio cholerae M66-2 7772699 YP_002810190.1 CDS VCM66_1423 NC_012578.1 1533563 1533895 R hypothetical protein complement(1533563..1533895) Vibrio cholerae M66-2 7772700 YP_002810191.1 CDS VCM66_1424 NC_012578.1 1533900 1534409 R hypothetical protein complement(1533900..1534409) Vibrio cholerae M66-2 7772701 YP_002810192.1 CDS VCM66_1425 NC_012578.1 1534366 1536162 D ATP-dependent protease LA-like protein 1534366..1536162 Vibrio cholerae M66-2 7772702 YP_002810193.1 CDS fabA NC_012578.1 1536227 1536745 D catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-(acyl carrier protein) dehydratase 1536227..1536745 Vibrio cholerae M66-2 7772703 YP_002810194.1 CDS rmf NC_012578.1 1536828 1537001 R ribosome modulation factor complement(1536828..1537001) Vibrio cholerae M66-2 7772704 YP_002810195.1 CDS VCM66_1428 NC_012578.1 1537168 1538862 R hypothetical protein complement(1537168..1538862) Vibrio cholerae M66-2 7772705 YP_002810196.1 CDS VCM66_1429 NC_012578.1 1538868 1540787 R Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase complement(1538868..1540787) Vibrio cholerae M66-2 7772706 YP_002810197.1 CDS VCM66_1430 NC_012578.1 1540765 1541007 R hypothetical protein complement(1540765..1541007) Vibrio cholerae M66-2 7772707 YP_002810198.1 CDS rlmL NC_012578.1 1541016 1543142 R catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase complement(1541016..1543142) Vibrio cholerae M66-2 7772708 YP_002810199.1 CDS VCM66_1432 NC_012578.1 1543401 1543532 R hypothetical protein complement(1543401..1543532) Vibrio cholerae M66-2 7772709 YP_002810200.1 CDS VCM66_1433 NC_012578.1 1543602 1544144 R hypothetical protein complement(1543602..1544144) Vibrio cholerae M66-2 7772710 YP_002810201.1 CDS pyrD NC_012578.1 1544299 1545309 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(1544299..1545309) Vibrio cholerae M66-2 7772711 YP_002810202.1 CDS VCM66_1435 NC_012578.1 1545383 1550224 R hypothetical protein complement(1545383..1550224) Vibrio cholerae M66-2 7772712 YP_002810203.1 CDS VCM66_1436 NC_012578.1 1550413 1550649 R hypothetical protein complement(1550413..1550649) Vibrio cholerae M66-2 7772713 YP_002810204.1 CDS pepN NC_012578.1 1550683 1553289 R aminopeptidase N complement(1550683..1553289) Vibrio cholerae M66-2 7772714 YP_002810205.1 CDS VCM66_1438 NC_012578.1 1553488 1554204 R hypothetical protein complement(1553488..1554204) Vibrio cholerae M66-2 7772715 YP_002810206.1 CDS prc NC_012578.1 1554313 1556310 R Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease complement(1554313..1556310) Vibrio cholerae M66-2 7772716 YP_002810207.1 CDS VCM66_1440 NC_012578.1 1556328 1556954 R affects solute and DNA transport through an unknown mechanism; putative solute/DNA competence effector complement(1556328..1556954) Vibrio cholerae M66-2 7772717 YP_002810208.1 CDS VCM66_1441 NC_012578.1 1557055 1557633 R GAF family protein complement(1557055..1557633) Vibrio cholerae M66-2 7772718 YP_002810209.1 CDS VCM66_1442 NC_012578.1 1557578 1559410 D ABC transporter ATP-binding protein 1557578..1559410 Vibrio cholerae M66-2 7772719 YP_002810210.1 CDS VCM66_1443 NC_012578.1 1559444 1560703 D PqiA family protein 1559444..1560703 Vibrio cholerae M66-2 7772720 YP_002810211.1 CDS VCM66_1444 NC_012578.1 1560713 1563352 D hypothetical protein 1560713..1563352 Vibrio cholerae M66-2 7772721 YP_002810212.1 CDS yebU NC_012578.1 1563383 1564894 D in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1563383..1564894 Vibrio cholerae M66-2 7772722 YP_002810213.1 CDS VCM66_1446 NC_012578.1 1565076 1565972 R hypothetical protein complement(1565076..1565972) Vibrio cholerae M66-2 7772723 YP_002810214.1 CDS VCM66_1447 NC_012578.1 1566011 1567360 D hypothetical protein 1566011..1567360 Vibrio cholerae M66-2 7772724 YP_002810215.1 CDS VCM66_1448 NC_012578.1 1567353 1567829 R hypothetical protein complement(1567353..1567829) Vibrio cholerae M66-2 7772725 YP_002810216.1 CDS aroH NC_012578.1 1567979 1569166 D tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1567979..1569166 Vibrio cholerae M66-2 7772726 YP_002810217.1 CDS VCM66_1450 NC_012578.1 1569178 1569660 D putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; putative nucleotide-binding protein 1569178..1569660 Vibrio cholerae M66-2 7772727 YP_002810218.1 CDS cobB NC_012578.1 1569795 1570574 R Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase complement(1569795..1570574) Vibrio cholerae M66-2 7772728 YP_002810219.1 CDS VCM66_1452 NC_012578.1 1570672 1571094 R hypothetical protein complement(1570672..1571094) Vibrio cholerae M66-2 7772729 YP_002810220.1 CDS fdnI NC_012578.1 1571081 1572154 R formate dehydrogenase, cytochrome B556 subunit complement(1571081..1572154) Vibrio cholerae M66-2 7772730 YP_002810221.1 CDS fdhB NC_012578.1 1572155 1572763 R formate dehydrogenase, iron-sulfur subunit complement(1572155..1572763) Vibrio cholerae M66-2 7772731 YP_002810222.1 CDS VCM66_1455 NC_012578.1 1572775 1575630 R putative formate dehydrogenase subunit alpha complement(1572775..1575630) Vibrio cholerae M66-2 7772732 YP_002810223.1 CDS VCM66_1456 NC_012578.1 1575642 1575839 R hypothetical protein complement(1575642..1575839) Vibrio cholerae M66-2 7772733 YP_002810224.1 CDS VCM66_1457 NC_012578.1 1575917 1576573 R putative chaperone, formate dehydrogenase-specific complement(1575917..1576573) Vibrio cholerae M66-2 7772734 YP_002810225.1 CDS VCM66_1458 NC_012578.1 1576599 1578260 R iron-sulfur cluster-binding protein complement(1576599..1578260) Vibrio cholerae M66-2 7772735 YP_002810226.1 CDS VCM66_1459 NC_012578.1 1578459 1579124 R hypothetical protein complement(1578459..1579124) Vibrio cholerae M66-2 7772736 YP_002810227.1 CDS VCM66_1460 NC_012578.1 1579051 1579527 R hypothetical protein complement(1579051..1579527) Vibrio cholerae M66-2 7772737 YP_002810228.1 CDS fdhD NC_012578.1 1579572 1580585 D formate dehydrogenase accessory protein 1579572..1580585 Vibrio cholerae M66-2 7772738 YP_002810229.1 CDS VCM66_1462 NC_012578.1 1580692 1582284 R ABC transporter ATP-binding protein complement(1580692..1582284) Vibrio cholerae M66-2 7772739 YP_002810230.1 CDS VCM66_1463 NC_012578.1 1582496 1584529 R sensor histidine kinase complement(1582496..1584529) Vibrio cholerae M66-2 7772740 YP_002810231.1 CDS VCM66_1464 NC_012578.1 1584519 1585973 R sigma-54 dependent response regulator complement(1584519..1585973) Vibrio cholerae M66-2 7772741 YP_002810232.1 CDS VCM66_1465 NC_012578.1 1586265 1587092 D hypothetical protein 1586265..1587092 Vibrio cholerae M66-2 7772742 YP_002810233.1 CDS VCM66_1466 NC_012578.1 1587099 1587797 D ABC transporter permease 1587099..1587797 Vibrio cholerae M66-2 7772743 YP_002810234.1 CDS VCM66_1467 NC_012578.1 1587806 1588528 D ABC transporter ATP-binding protein 1587806..1588528 Vibrio cholerae M66-2 7772744 YP_002810235.1 CDS mobA NC_012578.1 1588482 1589093 D in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 1588482..1589093 Vibrio cholerae M66-2 7772745 YP_002810236.1 CDS moeA-1 NC_012578.1 1589090 1590910 D putative bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobB/MoeA 1589090..1590910 Vibrio cholerae M66-2 7772746 YP_002810237.1 CDS VCM66_1472 NC_012578.1 1591789 1591950 R hypothetical protein complement(1591789..1591950) Vibrio cholerae M66-2 7773959 YP_002810238.1 CDS VCM66_1473 NC_012578.1 1591994 1592269 D hypothetical protein 1591994..1592269 Vibrio cholerae M66-2 7772748 YP_002810239.1 CDS VCM66_1474 NC_012578.1 1592476 1593384 R catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase complement(1592476..1593384) Vibrio cholerae M66-2 7772749 YP_002810240.1 CDS VCM66_1475 NC_012578.1 1593547 1594284 R hypothetical protein complement(1593547..1594284) Vibrio cholerae M66-2 7772750 YP_002810241.1 CDS VCM66_1476 NC_012578.1 1594261 1595175 D hypothetical protein 1594261..1595175 Vibrio cholerae M66-2 7772751 YP_002810242.1 CDS VCM66_1477 NC_012578.1 1595177 1597198 R methyl-accepting chemotaxis protein complement(1595177..1597198) Vibrio cholerae M66-2 7772752 YP_002810243.1 CDS nlpC NC_012578.1 1597287 1597787 D lipoprotein NlpC 1597287..1597787 Vibrio cholerae M66-2 7772753 YP_002810244.1 CDS VCM66_1479 NC_012578.1 1597797 1598228 R hypothetical protein complement(1597797..1598228) Vibrio cholerae M66-2 7772754 YP_002810245.1 CDS VCM66_1480 NC_012578.1 1598661 1599527 D hypothetical protein 1598661..1599527 Vibrio cholerae M66-2 7772755 YP_002810246.1 CDS VCM66_1481 NC_012578.1 1600131 1601516 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1600131..1601516 Vibrio cholerae M66-2 7772756 YP_002810247.1 CDS VCM66_1482 NC_012578.1 1601720 1602703 D hypothetical protein 1601720..1602703 Vibrio cholerae M66-2 7772757 YP_002810248.1 CDS ligA-2 NC_012578.1 1602710 1603558 R catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase complement(1602710..1603558) Vibrio cholerae M66-2 7772758 YP_002810249.1 CDS VCM66_1484 NC_012578.1 1603865 1605043 R hypothetical protein complement(1603865..1605043) Vibrio cholerae M66-2 7772759 YP_002810250.1 CDS tonB2 NC_012578.1 1605040 1605660 R tonB2 protein complement(1605040..1605660) Vibrio cholerae M66-2 7772760 YP_002810251.1 CDS exbD2 NC_012578.1 1605660 1606064 R TonB system transport protein ExbD2 complement(1605660..1606064) Vibrio cholerae M66-2 7772761 YP_002810252.1 CDS exbB2 NC_012578.1 1606061 1606603 R TonB system transport protein ExbB2 complement(1606061..1606603) Vibrio cholerae M66-2 7772762 YP_002810253.1 CDS VCM66_1488 NC_012578.1 1606610 1607983 R biopolymer transport protein complement(1606610..1607983) Vibrio cholerae M66-2 7772763 YP_002810254.1 CDS VCM66_1489 NC_012578.1 1607983 1608741 R hypothetical protein complement(1607983..1608741) Vibrio cholerae M66-2 7772764 YP_002810255.1 CDS ugpB NC_012578.1 1609060 1610364 D glycerol-3-phosphate ABC transporter substrate-binding protein 1609060..1610364 Vibrio cholerae M66-2 7772765 YP_002810256.1 CDS ugpA NC_012578.1 1610440 1611321 D glycerol-3-phosphate ABC transporter permease 1610440..1611321 Vibrio cholerae M66-2 7772766 YP_002810257.1 CDS ugpE NC_012578.1 1611331 1612173 D glycerol-3-phosphate ABC transporter permease 1611331..1612173 Vibrio cholerae M66-2 7772767 YP_002810258.1 CDS ugpC NC_012578.1 1612163 1613344 D part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 1612163..1613344 Vibrio cholerae M66-2 7772768 YP_002810259.1 CDS glpR NC_012578.1 1613369 1614130 D glycerol-3-phosphate regulon repressor 1613369..1614130 Vibrio cholerae M66-2 7772769 YP_002810260.1 CDS VCM66_1495 NC_012578.1 1614158 1614871 D putative glycerophosphoryl diester phosphodiesterase 1614158..1614871 Vibrio cholerae M66-2 7772770 YP_002810261.1 CDS VCM66_1496 NC_012578.1 1614947 1615459 R hypothetical protein complement(1614947..1615459) Vibrio cholerae M66-2 7772771 YP_002810262.1 CDS VCM66_1497 NC_012578.1 1615428 1615790 R hypothetical protein complement(1615428..1615790) Vibrio cholerae M66-2 7772772 YP_002810263.1 CDS VCM66_1498 NC_012578.1 1615925 1616959 R LacI family transcriptional regulator complement(1615925..1616959) Vibrio cholerae M66-2 7772773 YP_002810264.1 CDS bglA NC_012578.1 1616995 1618431 R 6-phospho-beta-glucosidase complement(1616995..1618431) Vibrio cholerae M66-2 7772774 YP_002810265.1 CDS VCM66_1500 NC_012578.1 1618722 1618823 D hypothetical protein 1618722..1618823 Vibrio cholerae M66-2 7772775 YP_002810266.1 CDS perA NC_012578.1 1618844 1621018 D catalase/peroxidase 1618844..1621018 Vibrio cholerae M66-2 7772776 YP_002810267.1 CDS VCM66_1502 NC_012578.1 1621083 1622012 R LysR family transcriptional regulator complement(1621083..1622012) Vibrio cholerae M66-2 7772777 YP_002810268.1 CDS VCM66_1503 NC_012578.1 1622076 1623248 D beta-lactamase-like protein 1622076..1623248 Vibrio cholerae M66-2 7772778 YP_002810269.1 CDS VCM66_1504 NC_012578.1 1623398 1624558 D hypothetical protein 1623398..1624558 Vibrio cholerae M66-2 7772779 YP_002810270.1 CDS VCM66_1505 NC_012578.1 1624551 1625810 D putative outer membrane protein TolC 1624551..1625810 Vibrio cholerae M66-2 7772780 YP_002810271.1 CDS VCM66_1506 NC_012578.1 1625810 1627024 D hypothetical protein 1625810..1627024 Vibrio cholerae M66-2 7772781 YP_002810272.1 CDS VCM66_1507 NC_012578.1 1627028 1628305 D hypothetical protein 1627028..1628305 Vibrio cholerae M66-2 7772782 YP_002810273.1 CDS VCM66_1508 NC_012578.1 1628305 1629006 D ABC transporter ATP-binding protein 1628305..1629006 Vibrio cholerae M66-2 7772783 YP_002810274.1 CDS VCM66_1509 NC_012578.1 1628972 1629073 D hypothetical protein 1628972..1629073 Vibrio cholerae M66-2 7772784 YP_002810275.1 CDS qxtB NC_012578.1 1629080 1630072 R quinol oxidase subunit II complement(1629080..1630072) Vibrio cholerae M66-2 7772785 YP_002810276.1 CDS qxtA NC_012578.1 1630069 1631406 R quinol oxidase subunit I complement(1630069..1631406) Vibrio cholerae M66-2 7772786 YP_002810277.1 CDS VCM66_1512 NC_012578.1 1631929 1632309 D hypothetical protein 1631929..1632309 Vibrio cholerae M66-2 7772787 YP_002810278.1 CDS fumC NC_012578.1 1632325 1633710 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1632325..1633710 Vibrio cholerae M66-2 7772788 YP_002810279.1 CDS VCM66_1514 NC_012578.1 1633855 1634238 R hypothetical protein complement(1633855..1634238) Vibrio cholerae M66-2 7772789 YP_002810280.1 CDS VCM66_1515 NC_012578.1 1634283 1634741 R hypothetical protein complement(1634283..1634741) Vibrio cholerae M66-2 7772790 YP_002810281.1 CDS VCM66_1516 NC_012578.1 1634771 1635088 R hypothetical protein complement(1634771..1635088) Vibrio cholerae M66-2 7772791 YP_002810282.1 CDS VCM66_1517 NC_012578.1 1635244 1636065 R hypothetical protein complement(1635244..1636065) Vibrio cholerae M66-2 7772792 YP_002810283.1 CDS VCM66_1519 NC_012578.1 1636287 1637957 R enterobactin synthetase component F-like protein complement(1636287..1637957) Vibrio cholerae M66-2 7772793 YP_002810284.1 CDS VCM66_1520 NC_012578.1 1638021 1638932 R LysR family transcriptional regulator complement(1638021..1638932) Vibrio cholerae M66-2 7772794 YP_002810285.1 CDS VCM66_1521 NC_012578.1 1639012 1640562 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 1639012..1640562 Vibrio cholerae M66-2 7772795 YP_002810286.1 CDS VCM66_1522 NC_012578.1 1640487 1643075 D hypothetical protein 1640487..1643075 Vibrio cholerae M66-2 7772796 YP_002810287.1 CDS sodC NC_012578.1 1643120 1643635 R superoxide dismutase, Cu-Zn complement(1643120..1643635) Vibrio cholerae M66-2 7772797 YP_002810288.1 CDS ankB NC_012578.1 1643675 1644241 R ankB protein complement(1643675..1644241) Vibrio cholerae M66-2 7772798 YP_002810289.1 CDS katB NC_012578.1 1644305 1646008 R catalase complement(1644305..1646008) Vibrio cholerae M66-2 7772799 YP_002810290.1 CDS VCM66_1526 NC_012578.1 1646181 1646282 R hypothetical protein complement(1646181..1646282) Vibrio cholerae M66-2 7772800 YP_002810291.1 CDS VCM66_1527 NC_012578.1 1646262 1646702 D hypothetical protein 1646262..1646702 Vibrio cholerae M66-2 7772801 YP_002810292.1 CDS alsR NC_012578.1 1646891 1647769 R LysR family transcriptional regulator complement(1646891..1647769) Vibrio cholerae M66-2 7772802 YP_002810293.1 CDS aldC NC_012578.1 1647878 1648663 D alpha-acetolactate decarboxylase 1647878..1648663 Vibrio cholerae M66-2 7772803 YP_002810294.1 CDS alsS NC_012578.1 1648802 1650505 D catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 1648802..1650505 Vibrio cholerae M66-2 7772804 YP_002810295.1 CDS alsO NC_012578.1 1650502 1651260 D oxidoreductase, short-chain dehydrogenase/reductase family 1650502..1651260 Vibrio cholerae M66-2 7772805 YP_002810296.1 CDS VCM66_1532 NC_012578.1 1651498 1652352 D EAL family protein 1651498..1652352 Vibrio cholerae M66-2 7772806 YP_002810297.1 CDS VCM66_1533 NC_012578.1 1652435 1653724 D GGDEF family protein 1652435..1653724 Vibrio cholerae M66-2 7772807 YP_002810298.1 CDS galM NC_012578.1 1653742 1654794 R catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase complement(1653742..1654794) Vibrio cholerae M66-2 7772808 YP_002810299.1 CDS galK NC_012578.1 1654803 1656020 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(1654803..1656020) Vibrio cholerae M66-2 7772809 YP_002810300.1 CDS galT NC_012578.1 1656029 1657147 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(1656029..1657147) Vibrio cholerae M66-2 7772810 YP_002810301.1 CDS VCM66_1537 NC_012578.1 1657537 1658970 R putative multidrug transporter complement(1657537..1658970) Vibrio cholerae M66-2 7772811 YP_002810302.1 CDS VCM66_1538 NC_012578.1 1659119 1659943 D ABC transporter substrate-binding protein 1659119..1659943 Vibrio cholerae M66-2 7772812 YP_002810303.1 CDS VCM66_1539 NC_012578.1 1660559 1661620 D GGDEF family protein 1660559..1661620 Vibrio cholerae M66-2 7774081 YP_002810304.1 CDS VCM66_1540 NC_012578.1 1661623 1662312 R hypothetical protein complement(1661623..1662312) Vibrio cholerae M66-2 7772814 YP_002810305.1 CDS VCM66_1541 NC_012578.1 1662427 1663230 R hypothetical protein complement(1662427..1663230) Vibrio cholerae M66-2 7772815 YP_002810306.1 CDS cheV-1 NC_012578.1 1663362 1664348 R chemotaxis protein CheV complement(1663362..1664348) Vibrio cholerae M66-2 7772816 YP_002810307.1 CDS VCM66_1543 NC_012578.1 1664367 1665143 R hypothetical protein complement(1664367..1665143) Vibrio cholerae M66-2 7772817 YP_002810308.1 CDS VCM66_1544 NC_012578.1 1665209 1665895 R response regulator complement(1665209..1665895) Vibrio cholerae M66-2 7772818 YP_002810309.1 CDS VCM66_1545 NC_012578.1 1665895 1667511 R putative sensor kinase citA complement(1665895..1667511) Vibrio cholerae M66-2 7772819 YP_002810310.1 CDS VCM66_1546 NC_012578.1 1668241 1669671 D hypothetical protein 1668241..1669671 Vibrio cholerae M66-2 7772820 YP_002810311.1 CDS VCM66_1547 NC_012578.1 1669683 1670657 D hypothetical protein 1669683..1670657 Vibrio cholerae M66-2 7772821 YP_002810312.1 CDS VCM66_1548 NC_012578.1 1670661 1671824 D hypothetical protein 1670661..1671824 Vibrio cholerae M66-2 7772822 YP_002810313.1 CDS VCM66_1549 NC_012578.1 1671743 1672969 D hypothetical protein 1671743..1672969 Vibrio cholerae M66-2 7772823 YP_002810314.1 CDS VCM66_1550 NC_012578.1 1672973 1673422 R NEDD4-binding protein complement(1672973..1673422) Vibrio cholerae M66-2 7772824 YP_002810315.1 CDS metA NC_012578.1 1673470 1674429 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 1673470..1674429 Vibrio cholerae M66-2 7772825 YP_002810316.1 CDS VCM66_1552 NC_012578.1 1674638 1675351 D putative fimbrial biogenesis and twitching motility protein 1674638..1675351 Vibrio cholerae M66-2 7772826 YP_002810317.1 CDS VCM66_1553 NC_012578.1 1675355 1675579 R hypothetical protein complement(1675355..1675579) Vibrio cholerae M66-2 7772827 YP_002810318.1 CDS VCM66_1554 NC_012578.1 1675778 1676866 R putative SAM-dependent methyltransferase complement(1675778..1676866) Vibrio cholerae M66-2 7772828 YP_002810319.1 CDS VCM66_1555 NC_012578.1 1676863 1677375 R hypothetical protein complement(1676863..1677375) Vibrio cholerae M66-2 7772829 YP_002810320.1 CDS VCM66_1556 NC_012578.1 1677543 1677776 D putative glutaredoxin 1677543..1677776 Vibrio cholerae M66-2 7772830 YP_002810321.1 CDS VCM66_1557 NC_012578.1 1677807 1678697 R LysR family transcriptional regulator complement(1677807..1678697) Vibrio cholerae M66-2 7772831 YP_002810322.1 CDS VCM66_1558 NC_012578.1 1678782 1679999 D putative multidrug resistance protein 1678782..1679999 Vibrio cholerae M66-2 7772832 YP_002810323.1 CDS VCM66_1559 NC_012578.1 1680056 1680604 D hypothetical protein 1680056..1680604 Vibrio cholerae M66-2 7772833 YP_002810324.1 CDS VCM66_1560 NC_012578.1 1680714 1688495 R RTX toxin complement(1680714..1688495) Vibrio cholerae M66-2 7772834 YP_002810325.1 CDS VCM66_1561 NC_012578.1 1688892 1690229 D agglutination protein 1688892..1690229 Vibrio cholerae M66-2 7772835 YP_002810326.1 CDS VCM66_1562 NC_012578.1 1690231 1690869 D putative outer membrane protein 1690231..1690869 Vibrio cholerae M66-2 7772836 YP_002810327.1 CDS nspC NC_012578.1 1691005 1692168 R carboxynorspermidine decarboxylase complement(1691005..1692168) Vibrio cholerae M66-2 7772837 YP_002810328.1 CDS VCM66_1564 NC_012578.1 1692404 1693648 R hypothetical protein complement(1692404..1693648) Vibrio cholerae M66-2 7772838 YP_002810329.1 CDS VCM66_1565 NC_012578.1 1693662 1696547 R aminotransferase, class III/decarboxylase, group II complement(1693662..1696547) Vibrio cholerae M66-2 7772839 YP_002810330.1 CDS nhaA NC_012578.1 1697145 1698293 R exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter complement(1697145..1698293) Vibrio cholerae M66-2 7772840 YP_002810331.1 CDS VCM66_1567 NC_012578.1 1698572 1699690 R hypothetical protein complement(1698572..1699690) Vibrio cholerae M66-2 7772841 YP_002810332.1 CDS VCM66_1568 NC_012578.1 1699691 1702201 R hypothetical protein complement(1699691..1702201) Vibrio cholerae M66-2 7772842 YP_002810333.1 CDS VCM66_1569 NC_012578.1 1702125 1702808 R ABC transporter ATP-binding protein complement(1702125..1702808) Vibrio cholerae M66-2 7772843 YP_002810334.1 CDS VCM66_1570 NC_012578.1 1702922 1704298 R hypothetical protein complement(1702922..1704298) Vibrio cholerae M66-2 7772844 YP_002810335.1 CDS VCM66_1571 NC_012578.1 1704426 1705862 D hypothetical protein 1704426..1705862 Vibrio cholerae M66-2 7772845 YP_002810336.1 CDS VCM66_1572 NC_012578.1 1705929 1706666 R hypothetical protein complement(1705929..1706666) Vibrio cholerae M66-2 7772846 YP_002810337.1 CDS VCM66_1573 NC_012578.1 1706588 1707793 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system complement(1706588..1707793) Vibrio cholerae M66-2 7772847 YP_002810338.1 CDS VCM66_1574 NC_012578.1 1708112 1708807 R ribosomal small subunit pseudouridine synthase A complement(1708112..1708807) Vibrio cholerae M66-2 7772848 YP_002810339.1 CDS VCM66_1575 NC_012578.1 1708752 1710725 D helicase-like protein 1708752..1710725 Vibrio cholerae M66-2 7772849 YP_002810340.1 CDS VCM66_1576 NC_012578.1 1710990 1711397 D hypothetical protein 1710990..1711397 Vibrio cholerae M66-2 7772850 YP_002810341.1 CDS VCM66_1577 NC_012578.1 1711409 1712068 D DNA-binding response regulator 1711409..1712068 Vibrio cholerae M66-2 7772851 YP_002810342.1 CDS VCM66_1578 NC_012578.1 1712043 1713431 D sensor histidine kinase 1712043..1713431 Vibrio cholerae M66-2 7772852 YP_002810343.1 CDS rplY NC_012578.1 1713589 1713867 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1713589..1713867 Vibrio cholerae M66-2 7772853 YP_002810344.1 CDS VCM66_1580 NC_012578.1 1714017 1714790 R EAL family protein complement(1714017..1714790) Vibrio cholerae M66-2 7772854 YP_002810345.1 CDS VCM66_1581 NC_012578.1 1714882 1715283 R hypothetical protein complement(1714882..1715283) Vibrio cholerae M66-2 7772855 YP_002810346.1 CDS VCM66_1582 NC_012578.1 1715474 1717264 D methyl-accepting chemotaxis protein 1715474..1717264 Vibrio cholerae M66-2 7772856 YP_002810347.1 CDS VCM66_1583 NC_012578.1 1717596 1718840 D hypothetical protein 1717596..1718840 Vibrio cholerae M66-2 7772857 YP_002810348.1 CDS VCM66_1584 NC_012578.1 1718957 1719568 R hypothetical protein complement(1718957..1719568) Vibrio cholerae M66-2 7772858 YP_002810349.1 CDS VCM66_1585 NC_012578.1 1719736 1719939 R hypothetical protein complement(1719736..1719939) Vibrio cholerae M66-2 7772859 YP_002810350.1 CDS VCM66_1586 NC_012578.1 1719980 1721893 D hypothetical protein 1719980..1721893 Vibrio cholerae M66-2 7772860 YP_002810351.1 CDS VCM66_1587 NC_012578.1 1721857 1721952 D hypothetical protein 1721857..1721952 Vibrio cholerae M66-2 7772861 YP_002810352.1 CDS VCM66_1588 NC_012578.1 1721974 1723620 R putative trypsin complement(1721974..1723620) Vibrio cholerae M66-2 7772862 YP_002810353.1 CDS vcc NC_012578.1 1723948 1726404 D collagenase 1723948..1726404 Vibrio cholerae M66-2 7772863 YP_002810354.1 CDS vieB NC_012578.1 1726438 1728099 R response regulator VieB complement(1726438..1728099) Vibrio cholerae M66-2 7772864 YP_002810355.1 CDS vieA NC_012578.1 1728111 1729865 R response regulator VieA complement(1728111..1729865) Vibrio cholerae M66-2 7772865 YP_002810356.1 CDS vieS NC_012578.1 1729870 1733310 R sensory box sensor histidine kinase/response regulator VieS complement(1729870..1733310) Vibrio cholerae M66-2 7772866 YP_002810357.1 CDS mgtE-1 NC_012578.1 1734101 1735456 D magnesium transporter 1734101..1735456 Vibrio cholerae M66-2 7772867 YP_002810358.1 CDS VCM66_1595 NC_012578.1 1735539 1736402 R hypothetical protein complement(1735539..1736402) Vibrio cholerae M66-2 7772868 YP_002810359.1 CDS sdaC-2 NC_012578.1 1736738 1737991 D serine transporter 1736738..1737991 Vibrio cholerae M66-2 7772869 YP_002810360.1 CDS VCM66_1598 NC_012578.1 1738160 1739107 D hypothetical protein 1738160..1739107 Vibrio cholerae M66-2 7772870 YP_002810361.1 CDS VCM66_1599 NC_012578.1 1739117 1740043 D ABC transporter ATP-binding protein 1739117..1740043 Vibrio cholerae M66-2 7772871 YP_002810362.1 CDS VCM66_1600 NC_012578.1 1740040 1741137 D multidrug ABC transporter permease 1740040..1741137 Vibrio cholerae M66-2 7772872 YP_002810363.1 CDS VCM66_1601 NC_012578.1 1741296 1741517 D hypothetical protein 1741296..1741517 Vibrio cholerae M66-2 7772873 YP_002810364.1 CDS VCM66_1602 NC_012578.1 1741523 1741789 R hypothetical protein complement(1741523..1741789) Vibrio cholerae M66-2 7772874 YP_002810365.1 CDS hslJ NC_012578.1 1741936 1742379 D heat shock protein HslJ 1741936..1742379 Vibrio cholerae M66-2 7772875 YP_002810366.1 CDS VCM66_1604 NC_012578.1 1742587 1743735 D putative ABC transporter solute-binding protein 1742587..1743735 Vibrio cholerae M66-2 7772876 YP_002810367.1 CDS VCM66_1605 NC_012578.1 1743749 1745449 D ABC transporter permease 1743749..1745449 Vibrio cholerae M66-2 7772877 YP_002810368.1 CDS VCM66_1606 NC_012578.1 1745415 1746077 D ABC transporter ATP-binding protein 1745415..1746077 Vibrio cholerae M66-2 7772878 YP_002810369.1 CDS VCM66_1607 NC_012578.1 1746070 1746690 D putative Inner membrane protein 1746070..1746690 Vibrio cholerae M66-2 7772879 YP_002810370.1 CDS VCM66_1608 NC_012578.1 1746749 1747456 R pseudouridine synthase Rlu family protein complement(1746749..1747456) Vibrio cholerae M66-2 7772880 YP_002810371.1 CDS VCM66_1609 NC_012578.1 1747555 1748901 R putative sodium-dependent transporter complement(1747555..1748901) Vibrio cholerae M66-2 7772881 YP_002810372.1 CDS cls NC_012578.1 1749457 1750911 D catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1749457..1750911 Vibrio cholerae M66-2 7772882 YP_002810373.1 CDS metC NC_012578.1 1750992 1752182 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 1750992..1752182 Vibrio cholerae M66-2 7772883 YP_002810374.1 CDS tag NC_012578.1 1752269 1752850 R DNA-3-methyladenine glycosidase I complement(1752269..1752850) Vibrio cholerae M66-2 7772884 YP_002810375.1 CDS VCM66_1613 NC_012578.1 1752937 1756050 R transporter, AcrB/D/F family complement(1752937..1756050) Vibrio cholerae M66-2 7772885 YP_002810376.1 CDS VCM66_1614 NC_012578.1 1756028 1757137 R putative periplasmic linker protein complement(1756028..1757137) Vibrio cholerae M66-2 7772886 YP_002810377.1 CDS VCM66_1615 NC_012578.1 1757109 1758140 R putative multidrug resistance protein complement(1757109..1758140) Vibrio cholerae M66-2 7772887 YP_002810378.1 CDS pspC NC_012578.1 1758312 1758728 R phage shock protein C complement(1758312..1758728) Vibrio cholerae M66-2 7772888 YP_002810379.1 CDS pspB NC_012578.1 1758694 1758927 R acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B complement(1758694..1758927) Vibrio cholerae M66-2 7772889 YP_002810380.1 CDS pspA NC_012578.1 1758941 1759609 R phage shock protein A complement(1758941..1759609) Vibrio cholerae M66-2 7772890 YP_002810381.1 CDS pspF NC_012578.1 1759819 1760835 D psp operon transcriptional activator 1759819..1760835 Vibrio cholerae M66-2 7772891 YP_002810382.1 CDS sapA NC_012578.1 1760949 1762571 D peptide ABC transporter substrate-binding protein 1760949..1762571 Vibrio cholerae M66-2 7772892 YP_002810383.1 CDS sapB NC_012578.1 1762571 1763533 D peptide ABC transporter permease 1762571..1763533 Vibrio cholerae M66-2 7772893 YP_002810384.1 CDS sapC NC_012578.1 1763520 1764407 D peptide ABC transporter permease 1763520..1764407 Vibrio cholerae M66-2 7772894 YP_002810385.1 CDS sapD NC_012578.1 1764407 1765402 D peptide ABC transporter ATP-binding protein 1764407..1765402 Vibrio cholerae M66-2 7772895 YP_002810386.1 CDS sapF NC_012578.1 1765399 1766187 D peptide ABC transporter ATP-binding protein 1765399..1766187 Vibrio cholerae M66-2 7772896 YP_002810387.1 CDS VCM66_1625 NC_012578.1 1766188 1766958 D hypothetical protein 1766188..1766958 Vibrio cholerae M66-2 7772897 YP_002810388.1 CDS VCM66_1626 NC_012578.1 1766995 1767549 R hypothetical protein complement(1766995..1767549) Vibrio cholerae M66-2 7772898 YP_002810389.1 CDS VCM66_1627 NC_012578.1 1767519 1768424 R catalyzes the hydrolysis of pyrophosphate to phosphate; putative manganese-dependent inorganic pyrophosphatase complement(1767519..1768424) Vibrio cholerae M66-2 7772899 YP_002810390.1 CDS VCM66_1628 NC_012578.1 1768571 1769818 D hypothetical protein 1768571..1769818 Vibrio cholerae M66-2 7772900 YP_002810391.1 CDS VCM66_1631 NC_012578.1 1771674 1771772 D hypothetical protein 1771674..1771772 Vibrio cholerae M66-2 7773960 YP_002810392.1 CDS torA NC_012578.1 1771825 1774287 R trimethylamine-N-oxide reductase complement(1771825..1774287) Vibrio cholerae M66-2 7772902 YP_002810393.1 CDS torC NC_012578.1 1774311 1775495 R cytochrome c-type protein TorC complement(1774311..1775495) Vibrio cholerae M66-2 7772903 YP_002810394.1 CDS napE NC_012578.1 1775542 1775760 R napE protein complement(1775542..1775760) Vibrio cholerae M66-2 7772904 YP_002810395.1 CDS VCM66_1635 NC_012578.1 1776404 1777246 R putative formate transporter complement(1776404..1777246) Vibrio cholerae M66-2 7772905 YP_002810396.1 CDS VCM66_1636 NC_012578.1 1777451 1777831 D DNA-binding protein inhibitor Id-2-like protein 1777451..1777831 Vibrio cholerae M66-2 7772906 YP_002810397.1 CDS VCM66_1637 NC_012578.1 1777935 1778765 D hypothetical protein 1777935..1778765 Vibrio cholerae M66-2 7772907 YP_002810398.1 CDS VCM66_1638 NC_012578.1 1778758 1779405 D hypothetical protein 1778758..1779405 Vibrio cholerae M66-2 7772908 YP_002810399.1 CDS VCM66_1639 NC_012578.1 1779538 1779807 D hypothetical protein 1779538..1779807 Vibrio cholerae M66-2 7772909 YP_002810400.1 CDS yciB NC_012578.1 1780040 1780585 D Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1780040..1780585 Vibrio cholerae M66-2 7772910 YP_002810401.1 CDS VCM66_1641 NC_012578.1 1780723 1781163 D Acyl-CoA thioester hydrolase 1780723..1781163 Vibrio cholerae M66-2 7772911 YP_002810402.1 CDS VCM66_1642 NC_012578.1 1781238 1781534 D unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1781238..1781534 Vibrio cholerae M66-2 7772912 YP_002810403.1 CDS VCM66_1643 NC_012578.1 1781443 1781934 D hypothetical protein 1781443..1781934 Vibrio cholerae M66-2 7772913 YP_002810404.1 CDS metE NC_012578.1 1782209 1784494 R catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase complement(1782209..1784494) Vibrio cholerae M66-2 7772914 YP_002810405.1 CDS VCM66_1645 NC_012578.1 1784748 1784843 D hypothetical protein 1784748..1784843 Vibrio cholerae M66-2 7772915 YP_002810406.1 CDS metR NC_012578.1 1784890 1785807 D transcriptional activator MetR 1784890..1785807 Vibrio cholerae M66-2 7772916 YP_002810407.1 CDS VCM66_1647 NC_012578.1 1785814 1786017 R hypothetical protein complement(1785814..1786017) Vibrio cholerae M66-2 7772917 YP_002810408.1 CDS VCM66_1648 NC_012578.1 1786131 1786817 R hypothetical protein complement(1786131..1786817) Vibrio cholerae M66-2 7772918 YP_002810409.1 CDS VCM66_1649 NC_012578.1 1787041 1789809 D zinc protease, insulinase family 1787041..1789809 Vibrio cholerae M66-2 7772919 YP_002810410.1 CDS VCM66_1650 NC_012578.1 1789943 1792399 R PAS/EAL family protein complement(1789943..1792399) Vibrio cholerae M66-2 7772920 YP_002810411.1 CDS VCM66_1651 NC_012578.1 1792679 1795048 D hypothetical protein 1792679..1795048 Vibrio cholerae M66-2 7772921 YP_002810412.1 CDS VCM66_1652 NC_012578.1 1795096 1795710 R hypothetical protein complement(1795096..1795710) Vibrio cholerae M66-2 7772922 YP_002810413.1 CDS VCM66_1653 NC_012578.1 1795788 1796231 D AsnC family transcriptional regulator 1795788..1796231 Vibrio cholerae M66-2 7772923 YP_002810414.1 CDS mukB NC_012578.1 1796313 1800788 R SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB complement(1796313..1800788) Vibrio cholerae M66-2 7772924 YP_002810415.1 CDS mukE NC_012578.1 1800785 1801528 R acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E complement(1800785..1801528) Vibrio cholerae M66-2 7772925 YP_002810416.1 CDS mukF NC_012578.1 1801488 1802825 R acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F complement(1801488..1802825) Vibrio cholerae M66-2 7772926 YP_002810417.1 CDS smtA NC_012578.1 1802837 1803619 R involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; putative metallothionein SmtA complement(1802837..1803619) Vibrio cholerae M66-2 7772927 YP_002810418.1 CDS VCM66_1658 NC_012578.1 1803709 1804557 D hypothetical protein 1803709..1804557 Vibrio cholerae M66-2 7772928 YP_002810419.1 CDS torR NC_012578.1 1804657 1805361 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1804657..1805361) Vibrio cholerae M66-2 7772929 YP_002810420.1 CDS torD NC_012578.1 1805586 1806248 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1805586..1806248 Vibrio cholerae M66-2 7772930 YP_002810421.1 CDS VCM66_1661 NC_012578.1 1806655 1807665 D LacI family transcriptional regulator 1806655..1807665 Vibrio cholerae M66-2 7772931 YP_002810422.1 CDS VCM66_1662 NC_012578.1 1808024 1808611 D hypothetical protein 1808024..1808611 Vibrio cholerae M66-2 7772932 YP_002810423.1 CDS VCM66_1663 NC_012578.1 1808966 1809655 D hypothetical protein 1808966..1809655 Vibrio cholerae M66-2 7772933 YP_002810424.1 CDS VCM66_1664 NC_012578.1 1809689 1810000 D hypothetical protein 1809689..1810000 Vibrio cholerae M66-2 7772934 YP_002810425.1 CDS VCM66_1665 NC_012578.1 1810005 1810823 R putative beta-ketoadipate enol-lactone hydrolase complement(1810005..1810823) Vibrio cholerae M66-2 7772935 YP_002810426.1 CDS glgA NC_012578.1 1811011 1812465 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(1811011..1812465) Vibrio cholerae M66-2 7772936 YP_002810427.1 CDS glgC NC_012578.1 1812467 1813684 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(1812467..1813684) Vibrio cholerae M66-2 7772937 YP_002810428.1 CDS VCM66_1668 NC_012578.1 1813816 1813950 D hypothetical protein 1813816..1813950 Vibrio cholerae M66-2 7772938 YP_002810429.1 CDS topA NC_012578.1 1814352 1816982 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(1814352..1816982) Vibrio cholerae M66-2 7772939 YP_002810430.1 CDS VCM66_1671 NC_012578.1 1817319 1817567 D hypothetical protein 1817319..1817567 Vibrio cholerae M66-2 7772940 YP_002810431.1 CDS aroA NC_012578.1 1817658 1818938 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(1817658..1818938) Vibrio cholerae M66-2 7772941 YP_002810432.1 CDS VCM66_1673 NC_012578.1 1818942 1819145 D hypothetical protein 1818942..1819145 Vibrio cholerae M66-2 7772942 YP_002810433.1 CDS VCM66_1674 NC_012578.1 1819120 1819224 D hypothetical protein 1819120..1819224 Vibrio cholerae M66-2 7772943 YP_002810434.1 CDS aat NC_012578.1 1819205 1819936 D leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 1819205..1819936 Vibrio cholerae M66-2 7772944 YP_002810435.1 CDS VCM66_1676 NC_012578.1 1819940 1820641 D Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase 1819940..1820641 Vibrio cholerae M66-2 7772945 YP_002810436.1 CDS infA NC_012578.1 1820725 1820943 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1820725..1820943 Vibrio cholerae M66-2 7772946 YP_002810437.1 CDS VCM66_1678 NC_012578.1 1821247 1822458 R enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity; trans-2-enoyl-CoA reductase complement(1821247..1822458) Vibrio cholerae M66-2 7772947 YP_002810438.1 CDS VCM66_1679 NC_012578.1 1822651 1824933 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(1822651..1824933) Vibrio cholerae M66-2 7772948 YP_002810439.1 CDS VCM66_1680 NC_012578.1 1824989 1825663 R TetR family transcriptional regulator complement(1824989..1825663) Vibrio cholerae M66-2 7772949 YP_002810440.1 CDS VCM66_1681 NC_012578.1 1825918 1826055 D hypothetical protein 1825918..1826055 Vibrio cholerae M66-2 7772950 YP_002810441.1 CDS VCM66_1682 NC_012578.1 1826034 1827059 D hypothetical protein 1826034..1827059 Vibrio cholerae M66-2 7772951 YP_002810442.1 CDS VCM66_1683 NC_012578.1 1827104 1827385 D hypothetical protein 1827104..1827385 Vibrio cholerae M66-2 7772952 YP_002810443.1 CDS gabD NC_012578.1 1827366 1828832 R succinate-semialdehyde dehydrogenase complement(1827366..1828832) Vibrio cholerae M66-2 7772953 YP_002810444.1 CDS VCM66_1685 NC_012578.1 1828850 1829479 R TetR family transcriptional regulator complement(1828850..1829479) Vibrio cholerae M66-2 7772954 YP_002810445.1 CDS VCM66_1686 NC_012578.1 1829405 1829629 D hypothetical protein 1829405..1829629 Vibrio cholerae M66-2 7772955 YP_002810446.1 CDS VCM66_1687 NC_012578.1 1829706 1830530 D hypothetical protein 1829706..1830530 Vibrio cholerae M66-2 7772956 YP_002810447.1 CDS VCM66_1688 NC_012578.1 1830430 1831656 D hypothetical protein 1830430..1831656 Vibrio cholerae M66-2 7772957 YP_002810448.1 CDS VCM66_1689 NC_012578.1 1831667 1832788 D hypothetical protein 1831667..1832788 Vibrio cholerae M66-2 7772958 YP_002810449.1 CDS VCM66_1690 NC_012578.1 1832804 1833682 R Small-conductance mechanosensitive channel complement(1832804..1833682) Vibrio cholerae M66-2 7772959 YP_002810450.1 CDS VCM66_1691 NC_012578.1 1834446 1834571 D hypothetical protein 1834446..1834571 Vibrio cholerae M66-2 7772960 YP_002810451.1 CDS pqiA NC_012578.1 1834735 1836039 D paraquat-inducible protein A 1834735..1836039 Vibrio cholerae M66-2 7772961 YP_002810452.1 CDS pqiB NC_012578.1 1836036 1837679 D paraquat-inducible protein B 1836036..1837679 Vibrio cholerae M66-2 7772962 YP_002810453.1 CDS VCM66_1694 NC_012578.1 1837676 1838254 D putative lipoprotein 1837676..1838254 Vibrio cholerae M66-2 7772963 YP_002810454.1 CDS VCM66_1695 NC_012578.1 1838470 1839564 D putative periplasmic linker protein 1838470..1839564 Vibrio cholerae M66-2 7772964 YP_002810455.1 CDS VCM66_1696 NC_012578.1 1839564 1842614 D transporter, AcrB/D/F family 1839564..1842614 Vibrio cholerae M66-2 7772965 YP_002810456.1 CDS VCM66_1697 NC_012578.1 1843226 1844461 D integrase, phage family 1843226..1844461 Vibrio cholerae M66-2 7774065 YP_002810457.1 CDS VCM66_1699 NC_012578.1 1845143 1848592 R putative helicase complement(1845143..1848592) Vibrio cholerae M66-2 7773961 YP_002810458.1 CDS VCM66_1700 NC_012578.1 1848583 1850034 R hypothetical protein complement(1848583..1850034) Vibrio cholerae M66-2 7772968 YP_002810459.1 CDS VCM66_1701 NC_012578.1 1850031 1850765 R chemotaxis protein MotB-like protein complement(1850031..1850765) Vibrio cholerae M66-2 7772969 YP_002810460.1 CDS VCM66_1702 NC_012578.1 1850758 1852878 R Restin-like protein complement(1850758..1852878) Vibrio cholerae M66-2 7772970 YP_002810461.1 CDS VCM66_1703 NC_012578.1 1852923 1855991 R putative type I restriction enzyme HsdR complement(1852923..1855991) Vibrio cholerae M66-2 7772971 YP_002810462.1 CDS VCM66_1704 NC_012578.1 1856019 1858010 R hypothetical protein complement(1856019..1858010) Vibrio cholerae M66-2 7772972 YP_002810463.1 CDS VCM66_1705 NC_012578.1 1858003 1859415 R hypothetical protein complement(1858003..1859415) Vibrio cholerae M66-2 7772973 YP_002810464.1 CDS VCM66_1706 NC_012578.1 1859416 1860804 R hypothetical protein complement(1859416..1860804) Vibrio cholerae M66-2 7772974 YP_002810465.1 CDS VCM66_1707 NC_012578.1 1860761 1863142 R putative DNA methylase HsdM complement(1860761..1863142) Vibrio cholerae M66-2 7772975 YP_002810466.1 CDS VCM66_1708 NC_012578.1 1863283 1865346 R hypothetical protein complement(1863283..1865346) Vibrio cholerae M66-2 7772976 YP_002810467.1 CDS VCM66_1709 NC_012578.1 1865328 1868990 R hypothetical protein complement(1865328..1868990) Vibrio cholerae M66-2 7772977 YP_002810468.1 CDS VCM66_1710 NC_012578.1 1869018 1869878 D hypothetical protein 1869018..1869878 Vibrio cholerae M66-2 7772978 YP_002810469.1 CDS VCM66_1711 NC_012578.1 1869943 1871013 R hypothetical protein complement(1869943..1871013) Vibrio cholerae M66-2 7772979 YP_002810470.1 CDS VCM66_1712 NC_012578.1 1871028 1872182 R N-acetylneuraminic acid mutarotase complement(1871028..1872182) Vibrio cholerae M66-2 7772980 YP_002810471.1 CDS VCM66_1713 NC_012578.1 1872364 1873200 R Putative HTH-type transcriptional regulator ybbH complement(1872364..1873200) Vibrio cholerae M66-2 7772981 YP_002810472.1 CDS VCM66_1714 NC_012578.1 1873329 1874225 R putative N-acetylneuraminate lyase complement(1873329..1874225) Vibrio cholerae M66-2 7772982 YP_002810473.1 CDS VCM66_1715 NC_012578.1 1874263 1875546 R Sialic acid TRAP transporter,large permease complement(1874263..1875546) Vibrio cholerae M66-2 7772983 YP_002810474.1 CDS VCM66_1716 NC_012578.1 1875554 1876075 R Sialic acid TRAP transporter small permease complement(1875554..1876075) Vibrio cholerae M66-2 7772984 YP_002810475.1 CDS dctP-1 NC_012578.1 1876126 1877091 R C4-dicarboxylate-binding periplasmic protein complement(1876126..1877091) Vibrio cholerae M66-2 7772985 YP_002810476.1 CDS VCM66_1718 NC_012578.1 1877122 1877415 D hypothetical protein 1877122..1877415 Vibrio cholerae M66-2 7772986 YP_002810477.1 CDS VCM66_1719 NC_012578.1 1877306 1878028 D Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 1877306..1878028 Vibrio cholerae M66-2 7772987 YP_002810478.1 CDS VCM66_1720 NC_012578.1 1878016 1878879 D catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 1878016..1878879 Vibrio cholerae M66-2 7772988 YP_002810479.1 CDS nagA-2 NC_012578.1 1878883 1880019 D N-acetylglucosamine-6-phosphate deacetylase 1878883..1880019 Vibrio cholerae M66-2 7772989 YP_002810480.1 CDS nanH NC_012578.1 1880364 1882787 D neuraminidase 1880364..1882787 Vibrio cholerae M66-2 7772990 YP_002810481.1 CDS VCM66_1723 NC_012578.1 1882934 1883140 R transcriptional regulator complement(1882934..1883140) Vibrio cholerae M66-2 7772991 YP_002810482.1 CDS VCM66_1724 NC_012578.1 1883254 1883730 D putative DNA repair protein RadC 1883254..1883730 Vibrio cholerae M66-2 7772992 YP_002810483.1 CDS VCM66_1725 NC_012578.1 1883727 1883864 D hypothetical protein 1883727..1883864 Vibrio cholerae M66-2 7772993 YP_002810484.1 CDS VCM66_1726 NC_012578.1 1883960 1884655 R hypothetical protein complement(1883960..1884655) Vibrio cholerae M66-2 7772994 YP_002810485.1 CDS orfB NC_012578.1 1884652 1885524 R ISVch4 transposase, OrfB complement(1884652..1885524) Vibrio cholerae M66-2 7772995 YP_002810486.1 CDS orfA NC_012578.1 1885521 1885865 R ISVch4 transposase, OrfA complement(1885521..1885865) Vibrio cholerae M66-2 7772996 YP_002810487.1 CDS VCM66_1729 NC_012578.1 1886108 1887094 D hypothetical protein 1886108..1887094 Vibrio cholerae M66-2 7772997 YP_002810488.1 CDS VCM66_1731 NC_012578.1 1888061 1888906 D hypothetical protein 1888061..1888906 Vibrio cholerae M66-2 7773962 YP_002810489.1 CDS VCM66_1732 NC_012578.1 1889021 1889251 R putative transcriptional regulator complement(1889021..1889251) Vibrio cholerae M66-2 7772999 YP_002810490.1 CDS VCM66_1733 NC_012578.1 1889851 1890054 D hypothetical protein 1889851..1890054 Vibrio cholerae M66-2 7773000 YP_002810491.1 CDS VCM66_1734 NC_012578.1 1890046 1890519 R hypothetical protein complement(1890046..1890519) Vibrio cholerae M66-2 7773001 YP_002810492.1 CDS VCM66_1735 NC_012578.1 1890643 1891062 R hypothetical protein complement(1890643..1891062) Vibrio cholerae M66-2 7773002 YP_002810493.1 CDS VCM66_1736 NC_012578.1 1891031 1891123 R hypothetical protein complement(1891031..1891123) Vibrio cholerae M66-2 7773003 YP_002810494.1 CDS phrB-1 NC_012578.1 1891179 1892564 D deoxyribodipyrimidine photolyase 1891179..1892564 Vibrio cholerae M66-2 7773004 YP_002810495.1 CDS VCM66_1738 NC_012578.1 1892561 1893268 D C factor cell-cell signaling protein 1892561..1893268 Vibrio cholerae M66-2 7773005 YP_002810496.1 CDS VCM66_1739 NC_012578.1 1893279 1893494 R hypothetical protein complement(1893279..1893494) Vibrio cholerae M66-2 7773006 YP_002810497.1 CDS VCM66_1740 NC_012578.1 1893591 1895354 R sigma-54 dependent transcriptional regulator complement(1893591..1895354) Vibrio cholerae M66-2 7773007 YP_002810498.1 CDS VCM66_1741 NC_012578.1 1895522 1895623 R hypothetical protein complement(1895522..1895623) Vibrio cholerae M66-2 7773008 YP_002810499.1 CDS aldA-2 NC_012578.1 1895635 1897155 D aldehyde dehydrogenase 1895635..1897155 Vibrio cholerae M66-2 7773009 YP_002810500.1 CDS frvA NC_012578.1 1897488 1897928 D PTS system fructose-specific transporter subunit IIA 1897488..1897928 Vibrio cholerae M66-2 7773010 YP_002810501.1 CDS frwBC NC_012578.1 1897940 1899343 D PTS system fructose-specific transporter subunit IIBC 1897940..1899343 Vibrio cholerae M66-2 7773011 YP_002810502.1 CDS frwABC NC_012578.1 1899418 1901283 R PTS system fructose-specific transporter subunit IIABC complement(1899418..1901283) Vibrio cholerae M66-2 7773012 YP_002810503.1 CDS frwB NC_012578.1 1901500 1901799 D PTS system fructose-specific transporter subunit IIB 1901500..1901799 Vibrio cholerae M66-2 7773013 YP_002810504.1 CDS VCM66_1747 NC_012578.1 1901808 1902587 D putative PTS system, nitrogen regulatory IIA component 1901808..1902587 Vibrio cholerae M66-2 7773014 YP_002810505.1 CDS VCM66_1748 NC_012578.1 1902579 1903418 R transcriptional regulator complement(1902579..1903418) Vibrio cholerae M66-2 7773015 YP_002810506.1 CDS fruA-1 NC_012578.1 1903790 1905691 D PTS system fructose-specific transporter subunit IIABC 1903790..1905691 Vibrio cholerae M66-2 7773016 YP_002810507.1 CDS manA-2 NC_012578.1 1905807 1906973 D mannose-6-phosphate isomerase 1905807..1906973 Vibrio cholerae M66-2 7773017 YP_002810508.1 CDS VCM66_1751 NC_012578.1 1907093 1907545 R hypothetical protein complement(1907093..1907545) Vibrio cholerae M66-2 7773018 YP_002810509.1 CDS VCM66_1752 NC_012578.1 1907734 1907841 R hypothetical protein complement(1907734..1907841) Vibrio cholerae M66-2 7773019 YP_002810510.1 CDS VCM66_1753 NC_012578.1 1907819 1907914 D hypothetical protein 1907819..1907914 Vibrio cholerae M66-2 7773020 YP_002810511.1 CDS VCM66_1754 NC_012578.1 1907881 1910091 R sensor histidine kinase complement(1907881..1910091) Vibrio cholerae M66-2 7773021 YP_002810512.1 CDS VCM66_1755 NC_012578.1 1910299 1910871 D hypothetical protein 1910299..1910871 Vibrio cholerae M66-2 7773022 YP_002810513.1 CDS nadA NC_012578.1 1910945 1912006 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(1910945..1912006) Vibrio cholerae M66-2 7773023 YP_002810514.1 CDS VCM66_1757 NC_012578.1 1912180 1912944 R hypothetical protein complement(1912180..1912944) Vibrio cholerae M66-2 7773024 YP_002810515.1 CDS pal NC_012578.1 1912960 1913478 R peptidoglycan-associated lipoprotein complement(1912960..1913478) Vibrio cholerae M66-2 7773025 YP_002810516.1 CDS tolB NC_012578.1 1913510 1914862 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(1913510..1914862) Vibrio cholerae M66-2 7773026 YP_002810517.1 CDS tolA NC_012578.1 1914877 1915947 R tolA protein complement(1914877..1915947) Vibrio cholerae M66-2 7773027 YP_002810518.1 CDS tolR NC_012578.1 1915965 1916405 R tolR membrane protein complement(1915965..1916405) Vibrio cholerae M66-2 7773028 YP_002810519.1 CDS tolQ NC_012578.1 1916408 1917091 R tolQ protein complement(1916408..1917091) Vibrio cholerae M66-2 7773029 YP_002810520.1 CDS VCM66_1763 NC_012578.1 1917081 1917548 R hypothetical protein complement(1917081..1917548) Vibrio cholerae M66-2 7773030 YP_002810521.1 CDS VCM66_1764 NC_012578.1 1917657 1917974 R hypothetical protein complement(1917657..1917974) Vibrio cholerae M66-2 7773031 YP_002810522.1 CDS VCM66_1765 NC_012578.1 1917967 1918074 R hypothetical protein complement(1917967..1918074) Vibrio cholerae M66-2 7773032 YP_002810523.1 CDS cydB-1 NC_012578.1 1918087 1919223 R cytochrome d ubiquinol oxidase subunit II complement(1918087..1919223) Vibrio cholerae M66-2 7773033 YP_002810524.1 CDS cydA-1 NC_012578.1 1919241 1920866 R cytochrome d ubiquinol oxidase subunit I complement(1919241..1920866) Vibrio cholerae M66-2 7773034 YP_002810525.1 CDS ruvB NC_012578.1 1921286 1922290 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(1921286..1922290) Vibrio cholerae M66-2 7773035 YP_002810526.1 CDS ruvA NC_012578.1 1922346 1922960 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(1922346..1922960) Vibrio cholerae M66-2 7773036 YP_002810527.1 CDS ruvC NC_012578.1 1923057 1923578 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1923057..1923578) Vibrio cholerae M66-2 7773037 YP_002810528.1 CDS cysS NC_012578.1 1923666 1925045 R catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase complement(1923666..1925045) Vibrio cholerae M66-2 7773038 YP_002810529.1 CDS ppiB NC_012578.1 1925191 1925685 D peptidyl-prolyl cis-trans isomerase B 1925191..1925685 Vibrio cholerae M66-2 7773039 YP_002810530.1 CDS VCM66_1773 NC_012578.1 1925726 1926466 D catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 1925726..1926466 Vibrio cholerae M66-2 7773040 YP_002810531.1 CDS VCM66_1774 NC_012578.1 1926562 1927776 D HD-GYP/EAL family protein 1926562..1927776 Vibrio cholerae M66-2 7773041 YP_002810532.1 CDS VCM66_1775 NC_012578.1 1927838 1928293 D hypothetical protein 1927838..1928293 Vibrio cholerae M66-2 7773042 YP_002810533.1 CDS VCM66_1776 NC_012578.1 1928325 1928999 R hypothetical protein complement(1928325..1928999) Vibrio cholerae M66-2 7773043 YP_002810534.1 CDS ompT NC_012578.1 1929118 1930224 R ompT protein complement(1929118..1930224) Vibrio cholerae M66-2 7773044 YP_002810535.1 CDS dinG NC_012578.1 1930627 1932738 D helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 1930627..1932738 Vibrio cholerae M66-2 7773045 YP_002810536.1 CDS VCM66_1779 NC_012578.1 1932776 1933555 D putative Inner membrane protein 1932776..1933555 Vibrio cholerae M66-2 7773046 YP_002810537.1 CDS priC NC_012578.1 1933540 1934103 D primosomal replication protein N'' 1933540..1934103 Vibrio cholerae M66-2 7773047 YP_002810538.1 CDS VCM66_1781 NC_012578.1 1934104 1934316 D hypothetical protein 1934104..1934316 Vibrio cholerae M66-2 7773048 YP_002810539.1 CDS VCM66_1782 NC_012578.1 1934340 1936460 R methyl-accepting chemotaxis protein complement(1934340..1936460) Vibrio cholerae M66-2 7773049 YP_002810540.1 CDS xth NC_012578.1 1936658 1937464 D removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1936658..1937464 Vibrio cholerae M66-2 7773050 YP_002810541.1 CDS VCM66_1784 NC_012578.1 1937523 1938200 R amino acid ABC transporter permease complement(1937523..1938200) Vibrio cholerae M66-2 7773051 YP_002810542.1 CDS VCM66_1785 NC_012578.1 1938203 1938985 R amino acid ABC transporter permease complement(1938203..1938985) Vibrio cholerae M66-2 7773052 YP_002810543.1 CDS VCM66_1786 NC_012578.1 1939091 1939873 R amino acid ABC transporter substrate-binding protein complement(1939091..1939873) Vibrio cholerae M66-2 7773053 YP_002810544.1 CDS VCM66_1787 NC_012578.1 1940052 1940822 R amino acid ABC transporter ATP-binding protein complement(1940052..1940822) Vibrio cholerae M66-2 7773054 YP_002810545.1 CDS VCM66_1788 NC_012578.1 1941527 1943083 D hypothetical protein 1941527..1943083 Vibrio cholerae M66-2 7773055 YP_002810546.1 CDS pflB NC_012578.1 1943262 1945625 D formate acetyltransferase 1943262..1945625 Vibrio cholerae M66-2 7773056 YP_002810547.1 CDS VCM66_1790 NC_012578.1 1945761 1946789 D hypothetical protein 1945761..1946789 Vibrio cholerae M66-2 7773057 YP_002810548.1 CDS VCM66_1791 NC_012578.1 1946807 1948687 R methyl-accepting chemotaxis protein complement(1946807..1948687) Vibrio cholerae M66-2 7773058 YP_002810549.1 CDS pflA NC_012578.1 1949020 1949760 D activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1949020..1949760 Vibrio cholerae M66-2 7773059 YP_002810550.1 CDS VCM66_1793 NC_012578.1 1949826 1950488 D hypothetical protein 1949826..1950488 Vibrio cholerae M66-2 7773060 YP_002810551.1 CDS VCM66_1794 NC_012578.1 1950597 1951109 D hypothetical protein 1950597..1951109 Vibrio cholerae M66-2 7773061 YP_002810552.1 CDS VCM66_1795 NC_012578.1 1951350 1953284 D hypothetical protein 1951350..1953284 Vibrio cholerae M66-2 7773062 YP_002810553.1 CDS VCM66_1796 NC_012578.1 1953429 1954700 D hypothetical protein 1953429..1954700 Vibrio cholerae M66-2 7773063 YP_002810554.1 CDS VCM66_1797 NC_012578.1 1954713 1956263 D SpoVR family protein 1954713..1956263 Vibrio cholerae M66-2 7773064 YP_002810555.1 CDS VCM66_1798 NC_012578.1 1956364 1956801 R IS1004 transposase complement(1956364..1956801) Vibrio cholerae M66-2 7773065 YP_002810556.1 CDS kdsB NC_012578.1 1956970 1957728 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(1956970..1957728) Vibrio cholerae M66-2 7773066 YP_002810557.1 CDS VCM66_1800 NC_012578.1 1957728 1957907 R hypothetical protein complement(1957728..1957907) Vibrio cholerae M66-2 7773067 YP_002810558.1 CDS lpxK NC_012578.1 1957888 1958898 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(1957888..1958898) Vibrio cholerae M66-2 7773068 YP_002810559.1 CDS msbA NC_012578.1 1958898 1960646 R involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding/permease complement(1958898..1960646) Vibrio cholerae M66-2 7773069 YP_002810560.1 CDS VCM66_1803 NC_012578.1 1960677 1962935 R Rec2-like protein complement(1960677..1962935) Vibrio cholerae M66-2 7773070 YP_002810561.1 CDS VCM66_1804 NC_012578.1 1962929 1963459 D hypothetical protein 1962929..1963459 Vibrio cholerae M66-2 7773071 YP_002810562.1 CDS VCM66_1805 NC_012578.1 1963468 1963605 D hypothetical protein 1963468..1963605 Vibrio cholerae M66-2 7773072 YP_002810563.1 CDS VCM66_1806 NC_012578.1 1963574 1964818 R part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE complement(1963574..1964818) Vibrio cholerae M66-2 7773073 YP_002810564.1 CDS VCM66_1807 NC_012578.1 1964819 1965505 R ABC transporter ATP-binding protein complement(1964819..1965505) Vibrio cholerae M66-2 7773074 YP_002810565.1 CDS VCM66_1808 NC_012578.1 1965498 1966718 R Lipoprotein-releasing system transmembrane protein lolC complement(1965498..1966718) Vibrio cholerae M66-2 7773075 YP_002810566.1 CDS VCM66_1809 NC_012578.1 1966882 1967457 D hypothetical protein 1966882..1967457 Vibrio cholerae M66-2 7773076 YP_002810567.1 CDS mfd NC_012578.1 1967460 1970927 D transcription-repair coupling factor 1967460..1970927 Vibrio cholerae M66-2 7773077 YP_002810568.1 CDS VCM66_1811 NC_012578.1 1971067 1971867 D hypothetical protein 1971067..1971867 Vibrio cholerae M66-2 7773078 YP_002810569.1 CDS VCM66_1812 NC_012578.1 1972202 1974277 D hemolysin-like protein 1972202..1974277 Vibrio cholerae M66-2 7773079 YP_002810570.1 CDS VCM66_1813 NC_012578.1 1974562 1975098 D putative ribosomal-protein-serine acetyltransferase 1974562..1975098 Vibrio cholerae M66-2 7773080 YP_002810571.1 CDS ndh NC_012578.1 1975211 1976515 R NADH dehydrogenase complement(1975211..1976515) Vibrio cholerae M66-2 7773081 YP_002810572.1 CDS VCM66_1815 NC_012578.1 1976601 1976741 D hypothetical protein 1976601..1976741 Vibrio cholerae M66-2 7773082 YP_002810573.1 CDS VCM66_1816 NC_012578.1 1976858 1977397 R hypothetical protein complement(1976858..1977397) Vibrio cholerae M66-2 7773083 YP_002810574.1 CDS VCM66_1817 NC_012578.1 1977577 1978437 R hypothetical protein complement(1977577..1978437) Vibrio cholerae M66-2 7773084 YP_002810575.1 CDS VCM66_1818 NC_012578.1 1978465 1979055 R hypothetical protein complement(1978465..1979055) Vibrio cholerae M66-2 7773085 YP_002810576.1 CDS VCM66_1819 NC_012578.1 1979108 1979497 R hypothetical protein complement(1979108..1979497) Vibrio cholerae M66-2 7773086 YP_002810577.1 CDS VCM66_1820 NC_012578.1 1979497 1980915 R hypothetical protein complement(1979497..1980915) Vibrio cholerae M66-2 7773087 YP_002810578.1 CDS VCM66_1821 NC_012578.1 1980928 1981278 R Hit family protein complement(1980928..1981278) Vibrio cholerae M66-2 7773088 YP_002810579.1 CDS VCM66_1822 NC_012578.1 1981511 1983529 D methyl-accepting chemotaxis protein 1981511..1983529 Vibrio cholerae M66-2 7773089 YP_002810580.1 CDS VCM66_1823 NC_012578.1 1983699 1984850 D hypothetical protein 1983699..1984850 Vibrio cholerae M66-2 7773090 YP_002810581.1 CDS fadR NC_012578.1 1985085 1985924 R Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator complement(1985085..1985924) Vibrio cholerae M66-2 7773091 YP_002810582.1 CDS nhaB NC_012578.1 1986569 1988161 D involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1986569..1988161 Vibrio cholerae M66-2 7773092 YP_002810583.1 CDS dsbB NC_012578.1 1988241 1988762 D disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1988241..1988762 Vibrio cholerae M66-2 7773093 YP_002810584.1 CDS VCM66_1827 NC_012578.1 1988838 1991720 R putative cell division protein FtsK complement(1988838..1991720) Vibrio cholerae M66-2 7773094 YP_002810585.1 CDS lrp NC_012578.1 1991898 1992392 R mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator complement(1991898..1992392) Vibrio cholerae M66-2 7773095 YP_002810586.1 CDS ald NC_012578.1 1992549 1993673 D alanine dehydrogenase 1992549..1993673 Vibrio cholerae M66-2 7773096 YP_002810587.1 CDS VCM66_1830 NC_012578.1 1993715 1994911 R hypothetical protein complement(1993715..1994911) Vibrio cholerae M66-2 7773097 YP_002810588.1 CDS cysB NC_012578.1 1994973 1995947 R LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB complement(1994973..1995947) Vibrio cholerae M66-2 7773098 YP_002810589.1 CDS VCM66_1832 NC_012578.1 1996033 1996182 R hypothetical protein complement(1996033..1996182) Vibrio cholerae M66-2 7773099 YP_002810590.1 CDS VCM66_1833 NC_012578.1 1996212 1997000 D hypothetical protein 1996212..1997000 Vibrio cholerae M66-2 7773100 YP_002810591.1 CDS miaE NC_012578.1 1997062 1997838 D tRNA-(MS[2]IO[6]A)-hydroxylase 1997062..1997838 Vibrio cholerae M66-2 7773101 YP_002810592.1 CDS pyrF NC_012578.1 1997896 1998591 R type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase complement(1997896..1998591) Vibrio cholerae M66-2 7773102 YP_002810593.1 CDS VCM66_1836 NC_012578.1 1998664 1999833 R hypothetical protein complement(1998664..1999833) Vibrio cholerae M66-2 7773103 YP_002810594.1 CDS VCM66_1837 NC_012578.1 1999845 2000126 R hypothetical protein complement(1999845..2000126) Vibrio cholerae M66-2 7773104 YP_002810595.1 CDS ihfB NC_012578.1 2000265 2000543 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta complement(2000265..2000543) Vibrio cholerae M66-2 7773105 YP_002810596.1 CDS rpsA NC_012578.1 2000831 2002501 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(2000831..2002501) Vibrio cholerae M66-2 7773106 YP_002810597.1 CDS cmk NC_012578.1 2002610 2003299 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(2002610..2003299) Vibrio cholerae M66-2 7773107 YP_002810598.1 CDS VCM66_1841 NC_012578.1 2003470 2003781 R hypothetical protein complement(2003470..2003781) Vibrio cholerae M66-2 7773108 YP_002810599.1 CDS ppiD NC_012578.1 2003916 2005775 R peptidyl-prolyl cis-trans isomerse D complement(2003916..2005775) Vibrio cholerae M66-2 7773109 YP_002810600.1 CDS hupB NC_012578.1 2005928 2006200 R DNA-binding protein HU-beta complement(2005928..2006200) Vibrio cholerae M66-2 7773110 YP_002810601.1 CDS lon NC_012578.1 2006384 2008744 R ATP-dependent protease LA complement(2006384..2008744) Vibrio cholerae M66-2 7773111 YP_002810602.1 CDS clpX NC_012578.1 2008867 2010147 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(2008867..2010147) Vibrio cholerae M66-2 7773112 YP_002810603.1 CDS clpP NC_012578.1 2010227 2010829 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(2010227..2010829) Vibrio cholerae M66-2 7773113 YP_002810604.1 CDS tig NC_012578.1 2010959 2012260 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(2010959..2012260) Vibrio cholerae M66-2 7773114 YP_002810605.1 CDS VCM66_1848 NC_012578.1 2012367 2012786 D hypothetical protein 2012367..2012786 Vibrio cholerae M66-2 7773115 YP_002810606.1 CDS dctB NC_012578.1 2012759 2014552 D putative C4-dicarboxylate transport sensor protein 2012759..2014552 Vibrio cholerae M66-2 7773116 YP_002810607.1 CDS dctD-1 NC_012578.1 2014555 2015895 D putative C4-dicarboxylate transport transcriptional regulatory protein 2014555..2015895 Vibrio cholerae M66-2 7773117 YP_002810608.1 CDS dctM NC_012578.1 2016011 2017372 R putative C4-dicarboxylate transport protein complement(2016011..2017372) Vibrio cholerae M66-2 7773118 YP_002810609.1 CDS VCM66_1852 NC_012578.1 2017376 2018074 R putative C4-dicarboxylate transport protein complement(2017376..2018074) Vibrio cholerae M66-2 7773119 YP_002810610.1 CDS dctP-2 NC_012578.1 2018106 2019104 R C4-dicarboxylate-binding periplasmic protein complement(2018106..2019104) Vibrio cholerae M66-2 7773120 YP_002810611.1 CDS VCM66_1854 NC_012578.1 2019192 2019287 R hypothetical protein complement(2019192..2019287) Vibrio cholerae M66-2 7773121 YP_002810612.1 CDS VCM66_1855 NC_012578.1 2019336 2020862 R hypothetical protein complement(2019336..2020862) Vibrio cholerae M66-2 7773122 YP_002810613.1 CDS VCM66_1856 NC_012578.1 2021033 2021203 R hypothetical protein complement(2021033..2021203) Vibrio cholerae M66-2 7773123 YP_002810614.1 CDS VCM66_1857 NC_012578.1 2021365 2021835 D hypothetical protein 2021365..2021835 Vibrio cholerae M66-2 7773124 YP_002810615.1 CDS VCM66_1858 NC_012578.1 2021799 2023766 D GGDEF/EAL family protein 2021799..2023766 Vibrio cholerae M66-2 7773125 YP_002810616.1 CDS VCM66_1859 NC_012578.1 2023845 2024603 D CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase-like protein 2023845..2024603 Vibrio cholerae M66-2 7773126 YP_002810617.1 CDS VCM66_1860 NC_012578.1 2024606 2025538 D putative phosphatidate cytidylyltransferase 2024606..2025538 Vibrio cholerae M66-2 7773127 YP_002810618.1 CDS VCM66_1861 NC_012578.1 2025546 2026217 D hypothetical protein 2025546..2026217 Vibrio cholerae M66-2 7773128 YP_002810619.1 CDS VCM66_1862 NC_012578.1 2026307 2026756 D hypothetical protein 2026307..2026756 Vibrio cholerae M66-2 7773129 YP_002810620.1 CDS VCM66_1863 NC_012578.1 2027050 2027670 D hypothetical protein 2027050..2027670 Vibrio cholerae M66-2 7773130 YP_002810621.1 CDS VCM66_1864 NC_012578.1 2027717 2028379 R hypothetical protein complement(2027717..2028379) Vibrio cholerae M66-2 7773131 YP_002810622.1 CDS VCM66_1865 NC_012578.1 2028692 2029987 R hypothetical protein complement(2028692..2029987) Vibrio cholerae M66-2 7773132 YP_002810623.1 CDS folD NC_012578.1 2030542 2031477 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 2030542..2031477 Vibrio cholerae M66-2 7774002 YP_002810624.1 CDS VCM66_1867 NC_012578.1 2031452 2031544 D hypothetical protein 2031452..2031544 Vibrio cholerae M66-2 7773134 YP_002810625.1 CDS pvcB NC_012578.1 2031760 2032623 D PvcB protein 2031760..2032623 Vibrio cholerae M66-2 7773135 YP_002810626.1 CDS VCM66_1869 NC_012578.1 2032608 2034071 D hypothetical protein 2032608..2034071 Vibrio cholerae M66-2 7773136 YP_002810627.1 CDS VCM66_1870 NC_012578.1 2034060 2034167 R hypothetical protein complement(2034060..2034167) Vibrio cholerae M66-2 7773137 YP_002810628.1 CDS VCM66_1871 NC_012578.1 2034202 2035131 R LysR family transcriptional regulator complement(2034202..2035131) Vibrio cholerae M66-2 7773138 YP_002810629.1 CDS VCM66_1872 NC_012578.1 2035290 2035481 D hypothetical protein 2035290..2035481 Vibrio cholerae M66-2 7773139 YP_002810630.1 CDS pvcA NC_012578.1 2035451 2037277 D pvcA protein 2035451..2037277 Vibrio cholerae M66-2 7773140 YP_002810631.1 CDS bisZ NC_012578.1 2037367 2039814 R biotin sulfoxide reductase complement(2037367..2039814) Vibrio cholerae M66-2 7773141 YP_002810632.1 CDS yecK NC_012578.1 2039837 2040943 R cytochrome c-type protein YecK complement(2039837..2040943) Vibrio cholerae M66-2 7773142 YP_002810633.1 CDS chiA-1 NC_012578.1 2041198 2043738 R chitinase complement(2041198..2043738) Vibrio cholerae M66-2 7773143 YP_002810634.1 CDS VCM66_1877 NC_012578.1 2044002 2045219 R NupC family protein complement(2044002..2045219) Vibrio cholerae M66-2 7773144 YP_002810635.1 CDS VCM66_1879 NC_012578.1 2045550 2046497 R LysR family transcriptional regulator complement(2045550..2046497) Vibrio cholerae M66-2 7773145 YP_002810636.1 CDS VCM66_1880 NC_012578.1 2046661 2047632 R putative lytic murein transglycosylase complement(2046661..2047632) Vibrio cholerae M66-2 7773146 YP_002810637.1 CDS VCM66_1881 NC_012578.1 2047657 2047965 R hypothetical protein complement(2047657..2047965) Vibrio cholerae M66-2 7773147 YP_002810638.1 CDS VCM66_1882 NC_012578.1 2047996 2048121 D hypothetical protein 2047996..2048121 Vibrio cholerae M66-2 7773148 YP_002810639.1 CDS minC NC_012578.1 2048135 2048797 D blocks the formation of polar Z-ring septums; septum formation inhibitor 2048135..2048797 Vibrio cholerae M66-2 7773149 YP_002810640.1 CDS minD NC_012578.1 2048800 2049630 D septum site-determining protein MinD 2048800..2049630 Vibrio cholerae M66-2 7773150 YP_002810641.1 CDS minE NC_012578.1 2049635 2049898 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 2049635..2049898 Vibrio cholerae M66-2 7773151 YP_002810642.1 CDS VCM66_1886 NC_012578.1 2050187 2050678 D lipoprotein 2050187..2050678 Vibrio cholerae M66-2 7773152 YP_002810643.1 CDS VCM66_1887 NC_012578.1 2050745 2051242 R hypothetical protein complement(2050745..2051242) Vibrio cholerae M66-2 7773153 YP_002810644.1 CDS VCM66_1890 NC_012578.1 2052886 2054766 D hypothetical protein 2052886..2054766 Vibrio cholerae M66-2 7773964 YP_002810645.1 CDS VCM66_1891 NC_012578.1 2054942 2056996 D methyl-accepting chemotaxis protein 2054942..2056996 Vibrio cholerae M66-2 7773155 YP_002810646.1 CDS VCM66_1892 NC_012578.1 2057049 2057594 R HTH_3 family transcriptional regulator complement(2057049..2057594) Vibrio cholerae M66-2 7773156 YP_002810647.1 CDS VCM66_1893 NC_012578.1 2057606 2057701 R hypothetical protein complement(2057606..2057701) Vibrio cholerae M66-2 7773157 YP_002810648.1 CDS benE NC_012578.1 2057682 2058845 D benzoate transport protein 2057682..2058845 Vibrio cholerae M66-2 7773158 YP_002810649.1 CDS menE NC_012578.1 2058874 2060304 R O-succinylbenzoic acid--CoA ligase complement(2058874..2060304) Vibrio cholerae M66-2 7773159 YP_002810650.1 CDS menC NC_012578.1 2060280 2061278 R catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase complement(2060280..2061278) Vibrio cholerae M66-2 7773160 YP_002810651.1 CDS menB NC_012578.1 2061366 2062256 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase complement(2061366..2062256) Vibrio cholerae M66-2 7773161 YP_002810652.1 CDS VCM66_1898 NC_012578.1 2062257 2063048 R catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB complement(2062257..2063048) Vibrio cholerae M66-2 7773162 YP_002810653.1 CDS menD NC_012578.1 2063038 2064750 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(2063038..2064750) Vibrio cholerae M66-2 7773163 YP_002810654.1 CDS menF NC_012578.1 2064747 2066054 R menaquinone-specific isochorismate synthase complement(2064747..2066054) Vibrio cholerae M66-2 7773164 YP_002810655.1 CDS VCM66_1901 NC_012578.1 2066269 2067483 D broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 2066269..2067483 Vibrio cholerae M66-2 7773165 YP_002810656.1 CDS VCM66_1902 NC_012578.1 2067519 2068220 D hypothetical protein 2067519..2068220 Vibrio cholerae M66-2 7773166 YP_002810657.1 CDS dgt NC_012578.1 2068277 2069602 D dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 2068277..2069602 Vibrio cholerae M66-2 7773167 YP_002810658.1 CDS VCM66_1904 NC_012578.1 2069596 2070198 R hypothetical protein complement(2069596..2070198) Vibrio cholerae M66-2 7773168 YP_002810659.1 CDS VCM66_1905 NC_012578.1 2070085 2070753 D hypothetical protein 2070085..2070753 Vibrio cholerae M66-2 7773169 YP_002810660.1 CDS VCM66_1906 NC_012578.1 2070710 2070820 D hypothetical protein 2070710..2070820 Vibrio cholerae M66-2 7773170 YP_002810661.1 CDS VCM66_1907 NC_012578.1 2070829 2072676 R putative peptidase complement(2070829..2072676) Vibrio cholerae M66-2 7773171 YP_002810662.1 CDS rnd NC_012578.1 2072889 2074034 R ribonuclease D complement(2072889..2074034) Vibrio cholerae M66-2 7773172 YP_002810663.1 CDS fadD NC_012578.1 2074120 2075820 R Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase complement(2074120..2075820) Vibrio cholerae M66-2 7773173 YP_002810664.1 CDS VCM66_1910 NC_012578.1 2075945 2076799 R putative serine hydrolase complement(2075945..2076799) Vibrio cholerae M66-2 7773174 YP_002810665.1 CDS VCM66_1911 NC_012578.1 2076796 2077404 R putative outer membrane lipoprotein Slp complement(2076796..2077404) Vibrio cholerae M66-2 7773175 YP_002810666.1 CDS VCM66_1912 NC_012578.1 2077370 2077675 R hypothetical protein complement(2077370..2077675) Vibrio cholerae M66-2 7773176 YP_002810667.1 CDS VCM66_1913 NC_012578.1 2077735 2078448 R hypothetical protein complement(2077735..2078448) Vibrio cholerae M66-2 7773177 YP_002810668.1 CDS VCM66_1914 NC_012578.1 2078445 2080385 R ATP-dependent helicase, DinG family complement(2078445..2080385) Vibrio cholerae M66-2 7773178 YP_002810669.1 CDS VCM66_1915 NC_012578.1 2080339 2080776 D hypothetical protein 2080339..2080776 Vibrio cholerae M66-2 7773179 YP_002810670.1 CDS purU NC_012578.1 2080950 2081783 D produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 2080950..2081783 Vibrio cholerae M66-2 7773180 YP_002810671.1 CDS fadH NC_012578.1 2081857 2083857 R 2,4-dienoyl-CoA reductase complement(2081857..2083857) Vibrio cholerae M66-2 7773181 YP_002810672.1 CDS sppA NC_012578.1 2084087 2085937 D protease IV 2084087..2085937 Vibrio cholerae M66-2 7773182 YP_002810673.1 CDS ansA NC_012578.1 2086054 2087067 D converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 2086054..2087067 Vibrio cholerae M66-2 7773183 YP_002810674.1 CDS VCM66_1920 NC_012578.1 2087165 2087452 R hypothetical protein complement(2087165..2087452) Vibrio cholerae M66-2 7773184 YP_002810675.1 CDS VCM66_1921 NC_012578.1 2087556 2088380 D hypothetical protein 2087556..2088380 Vibrio cholerae M66-2 7773185 YP_002810676.1 CDS VCM66_1922 NC_012578.1 2088541 2088984 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(2088541..2088984) Vibrio cholerae M66-2 7773186 YP_002810677.1 CDS VCM66_1923 NC_012578.1 2088990 2089136 D hypothetical protein 2088990..2089136 Vibrio cholerae M66-2 7773187 YP_002810678.1 CDS gapA-1 NC_012578.1 2089284 2090279 D glyceraldehyde 3-phosphate dehydrogenase 2089284..2090279 Vibrio cholerae M66-2 7773188 YP_002810679.1 CDS VCM66_1925 NC_012578.1 2090427 2091317 D hypothetical protein 2090427..2091317 Vibrio cholerae M66-2 7773189 YP_002810680.1 CDS VCM66_1926 NC_012578.1 2091752 2092756 D hypothetical protein 2091752..2092756 Vibrio cholerae M66-2 7773190 YP_002810681.1 CDS rrmA NC_012578.1 2092893 2093729 D methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase A 2092893..2093729 Vibrio cholerae M66-2 7773191 YP_002810682.1 CDS VCM66_1928 NC_012578.1 2093750 2094727 D hypothetical protein 2093750..2094727 Vibrio cholerae M66-2 7773192 YP_002810683.1 CDS VCM66_1929 NC_012578.1 2094867 2095223 D hypothetical protein 2094867..2095223 Vibrio cholerae M66-2 7773193 YP_002810684.1 CDS cheV-2 NC_012578.1 2095297 2096241 R chemotaxis protein CheV complement(2095297..2096241) Vibrio cholerae M66-2 7773194 YP_002810685.1 CDS VCM66_1931 NC_012578.1 2096346 2097563 R ROK family transcriptional regulator complement(2096346..2097563) Vibrio cholerae M66-2 7773195 YP_002810686.1 CDS pykA-1 NC_012578.1 2098008 2099453 D pyruvate kinase II 2098008..2099453 Vibrio cholerae M66-2 7773196 YP_002810687.1 CDS VCM66_1933 NC_012578.1 2099495 2100664 R hypothetical protein complement(2099495..2100664) Vibrio cholerae M66-2 7773197 YP_002810688.1 CDS VCM66_1934 NC_012578.1 2100671 2100796 R hypothetical protein complement(2100671..2100796) Vibrio cholerae M66-2 7773198 YP_002810689.1 CDS VCM66_1935 NC_012578.1 2100896 2101486 D hypothetical protein 2100896..2101486 Vibrio cholerae M66-2 7773199 YP_002810690.1 CDS VCM66_1936 NC_012578.1 2101870 2103453 D sodium-dependent transporter 2101870..2103453 Vibrio cholerae M66-2 7773200 YP_002810691.1 CDS ptsG NC_012578.1 2103666 2105168 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC complement(2103666..2105168) Vibrio cholerae M66-2 7773201 YP_002810692.1 CDS VCM66_1938 NC_012578.1 2105540 2106307 R Putative deoxyribonuclease complement(2105540..2106307) Vibrio cholerae M66-2 7773202 YP_002810693.1 CDS holB NC_012578.1 2106298 2107272 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' complement(2106298..2107272) Vibrio cholerae M66-2 7773203 YP_002810694.1 CDS tmk NC_012578.1 2107265 2107903 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(2107265..2107903) Vibrio cholerae M66-2 7773204 YP_002810695.1 CDS VCM66_1941 NC_012578.1 2107900 2108916 R hypothetical protein complement(2107900..2108916) Vibrio cholerae M66-2 7773205 YP_002810696.1 CDS pabC NC_012578.1 2108913 2109746 R catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase complement(2108913..2109746) Vibrio cholerae M66-2 7773206 YP_002810697.1 CDS fabF NC_012578.1 2109794 2111038 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II complement(2109794..2111038) Vibrio cholerae M66-2 7773207 YP_002810698.1 CDS acpP NC_012578.1 2111127 2111459 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(2111127..2111459) Vibrio cholerae M66-2 7773208 YP_002810699.1 CDS fabG NC_012578.1 2111599 2112345 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(2111599..2112345) Vibrio cholerae M66-2 7773209 YP_002810700.1 CDS fabD NC_012578.1 2112361 2113299 R malonyl CoA-acyl carrier protein transacylase complement(2112361..2113299) Vibrio cholerae M66-2 7773210 YP_002810701.1 CDS fabH-1 NC_012578.1 2113354 2114304 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-(acyl carrier protein) synthase III complement(2113354..2114304) Vibrio cholerae M66-2 7773211 YP_002810702.1 CDS plsX NC_012578.1 2114310 2115335 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX complement(2114310..2115335) Vibrio cholerae M66-2 7773212 YP_002810703.1 CDS rpmF NC_012578.1 2115345 2115515 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(2115345..2115515) Vibrio cholerae M66-2 7773213 YP_002810704.1 CDS VCM66_1950 NC_012578.1 2115550 2116074 R hypothetical protein complement(2115550..2116074) Vibrio cholerae M66-2 7773214 YP_002810705.1 CDS VCM66_1951 NC_012578.1 2116222 2116803 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 2116222..2116803 Vibrio cholerae M66-2 7773215 YP_002810706.1 CDS rluC NC_012578.1 2116904 2117851 R ribosomal large subunit pseudouridine synthase C complement(2116904..2117851) Vibrio cholerae M66-2 7773216 YP_002810707.1 CDS VCM66_1953 NC_012578.1 2117765 2118004 D hypothetical protein 2117765..2118004 Vibrio cholerae M66-2 7773217 YP_002810708.1 CDS rne NC_012578.1 2118463 2121621 D ribonuclease E 2118463..2121621 Vibrio cholerae M66-2 7773218 YP_002810709.1 CDS VCM66_1955 NC_012578.1 2121969 2123534 D sulfate permease family protein 2121969..2123534 Vibrio cholerae M66-2 7773219 YP_002810710.1 CDS VCM66_1956 NC_012578.1 2123652 2124527 D hypothetical protein 2123652..2124527 Vibrio cholerae M66-2 7773220 YP_002810711.1 CDS adhE NC_012578.1 2124637 2127321 R bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(2124637..2127321) Vibrio cholerae M66-2 7773221 YP_002810712.1 CDS VCM66_1958 NC_012578.1 2127542 2127649 D hypothetical protein 2127542..2127649 Vibrio cholerae M66-2 7773222 YP_002810713.1 CDS VCM66_1959 NC_012578.1 2127948 2128586 D hypothetical protein 2127948..2128586 Vibrio cholerae M66-2 7773223 YP_002810714.1 CDS asd NC_012578.1 2128676 2129788 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(2128676..2129788) Vibrio cholerae M66-2 7773224 YP_002810715.1 CDS yqkI NC_012578.1 2130213 2131658 D Na+/H+ antiporter 2130213..2131658 Vibrio cholerae M66-2 7773225 YP_002810716.1 CDS VCM66_1962 NC_012578.1 2131693 2132898 R Hpt family protein complement(2131693..2132898) Vibrio cholerae M66-2 7773226 YP_002810717.1 CDS VCM66_1963 NC_012578.1 2133061 2134062 R nucleoid-associated protein NdpA complement(2133061..2134062) Vibrio cholerae M66-2 7773227 YP_002810718.1 CDS VCM66_1964 NC_012578.1 2134147 2134362 D hypothetical protein 2134147..2134362 Vibrio cholerae M66-2 7773228 YP_002810719.1 CDS VCM66_1965 NC_012578.1 2134397 2136199 D putative Inner membrane protein 2134397..2136199 Vibrio cholerae M66-2 7773229 YP_002810720.1 CDS VCM66_1966 NC_012578.1 2136657 2137577 R histone deacetylase/AcuC/AphA family protein complement(2136657..2137577) Vibrio cholerae M66-2 7774066 YP_002810721.1 CDS topB NC_012578.1 2137598 2139541 R decatenates replicating daughter chromosomes; DNA topoisomerase III complement(2137598..2139541) Vibrio cholerae M66-2 7773231 YP_002810722.1 CDS VCM66_1968 NC_012578.1 2139626 2139958 R putative monothiol glutaredoxin complement(2139626..2139958) Vibrio cholerae M66-2 7773232 YP_002810723.1 CDS sodB NC_012578.1 2140210 2140794 D superoxide dismutase, Fe 2140210..2140794 Vibrio cholerae M66-2 7773233 YP_002810724.1 CDS VCM66_1970 NC_012578.1 2140876 2141412 D hypothetical protein 2140876..2141412 Vibrio cholerae M66-2 7773234 YP_002810725.1 CDS VCM66_1971 NC_012578.1 2141781 2142461 D short chain dehydrogenase 2141781..2142461 Vibrio cholerae M66-2 7773235 YP_002810726.1 CDS vacJ NC_012578.1 2142474 2143238 R vacJ lipoprotein complement(2142474..2143238) Vibrio cholerae M66-2 7773236 YP_002810727.1 CDS ccmH NC_012578.1 2143291 2144505 R cytochrome c-type biogenesis protein CcmH complement(2143291..2144505) Vibrio cholerae M66-2 7773237 YP_002810728.1 CDS VCM66_1974 NC_012578.1 2144508 2144984 R cytochrome c-type biogenesis protein complement(2144508..2144984) Vibrio cholerae M66-2 7773238 YP_002810729.1 CDS dsbE NC_012578.1 2144981 2145535 R thiol:disulfide interchange protein DsbE complement(2144981..2145535) Vibrio cholerae M66-2 7773239 YP_002810730.1 CDS ccmF NC_012578.1 2145536 2147491 R cytochrome c-type biogenesis protein CcmF complement(2145536..2147491) Vibrio cholerae M66-2 7773240 YP_002810731.1 CDS ccmE NC_012578.1 2147488 2147970 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(2147488..2147970) Vibrio cholerae M66-2 7773241 YP_002810732.1 CDS ccmD NC_012578.1 2147967 2148173 R heme exporter protein D complement(2147967..2148173) Vibrio cholerae M66-2 7773242 YP_002810733.1 CDS ccmC NC_012578.1 2148173 2148925 R heme exporter protein C complement(2148173..2148925) Vibrio cholerae M66-2 7773243 YP_002810734.1 CDS ccmB NC_012578.1 2149016 2149684 R heme exporter protein B complement(2149016..2149684) Vibrio cholerae M66-2 7773244 YP_002810735.1 CDS ccmA NC_012578.1 2149681 2150304 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(2149681..2150304) Vibrio cholerae M66-2 7773245 YP_002810736.1 CDS VCM66_1982 NC_012578.1 2150678 2151181 R hypothetical protein complement(2150678..2151181) Vibrio cholerae M66-2 7773246 YP_002810737.1 CDS cheW-1 NC_012578.1 2151157 2151681 R purine-binding chemotaxis protein CheW complement(2151157..2151681) Vibrio cholerae M66-2 7773247 YP_002810738.1 CDS VCM66_1984 NC_012578.1 2151690 2152706 R hypothetical protein complement(2151690..2152706) Vibrio cholerae M66-2 7773248 YP_002810739.1 CDS VCM66_1985 NC_012578.1 2152699 2153475 R ParA family protein complement(2152699..2153475) Vibrio cholerae M66-2 7773249 YP_002810740.1 CDS cheB-2 NC_012578.1 2153485 2154618 R regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase complement(2153485..2154618) Vibrio cholerae M66-2 7773250 YP_002810741.1 CDS cheA-2 NC_012578.1 2154645 2157002 R chemotaxis protein CheA complement(2154645..2157002) Vibrio cholerae M66-2 7773251 YP_002810742.1 CDS cheZ NC_012578.1 2157012 2157731 R chemotaxis protein CheZ complement(2157012..2157731) Vibrio cholerae M66-2 7773252 YP_002810743.1 CDS cheY-3 NC_012578.1 2157787 2158179 R chemotaxis protein CheY complement(2157787..2158179) Vibrio cholerae M66-2 7773253 YP_002810744.1 CDS fliA NC_012578.1 2158201 2158935 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor complement(2158201..2158935) Vibrio cholerae M66-2 7773254 YP_002810745.1 CDS VCM66_1991 NC_012578.1 2158928 2159869 R MinD-like protein complement(2158928..2159869) Vibrio cholerae M66-2 7773255 YP_002810746.1 CDS flhF NC_012578.1 2159829 2161316 R positive regulator of class III flagellar genes; flagellar biosynthesis regulator FlhF complement(2159829..2161316) Vibrio cholerae M66-2 7773256 YP_002810747.1 CDS flhA NC_012578.1 2161351 2163444 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(2161351..2163444) Vibrio cholerae M66-2 7773257 YP_002810748.1 CDS VCM66_1995 NC_012578.1 2164243 2164359 D hypothetical protein 2164243..2164359 Vibrio cholerae M66-2 7773965 YP_002810749.1 CDS VCM66_1996 NC_012578.1 2164394 2167213 D peptidase, insulinase family 2164394..2167213 Vibrio cholerae M66-2 7773259 YP_002810750.1 CDS VCM66_1997 NC_012578.1 2167210 2167806 R hypothetical protein complement(2167210..2167806) Vibrio cholerae M66-2 7773260 YP_002810751.1 CDS argS NC_012578.1 2167940 2169739 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2167940..2169739 Vibrio cholerae M66-2 7773261 YP_002810752.1 CDS VCM66_1999 NC_012578.1 2169830 2170273 D histidine triad family protein 2169830..2170273 Vibrio cholerae M66-2 7773262 YP_002810753.1 CDS feoC NC_012578.1 2170535 2170765 R hypothetical protein complement(2170535..2170765) Vibrio cholerae M66-2 7773263 YP_002810754.1 CDS feoB NC_012578.1 2170762 2173038 R ferrous iron transport protein B complement(2170762..2173038) Vibrio cholerae M66-2 7773264 YP_002810755.1 CDS feoA NC_012578.1 2173035 2173265 R ferrous iron transport protein A complement(2173035..2173265) Vibrio cholerae M66-2 7773265 YP_002810756.1 CDS VCM66_2003 NC_012578.1 2173889 2173996 D hypothetical protein 2173889..2173996 Vibrio cholerae M66-2 7773266 YP_002810757.1 CDS VCM66_2004 NC_012578.1 2174037 2177402 R AraC family transcriptional regulator complement(2174037..2177402) Vibrio cholerae M66-2 7773267 YP_002810758.1 CDS znuA NC_012578.1 2177584 2178477 R zinc ABC transporter periplasmic zinc-binding protein complement(2177584..2178477) Vibrio cholerae M66-2 7773268 YP_002810759.1 CDS znuC NC_012578.1 2178552 2179340 D zinc ABC transporter ATP-binding protein 2178552..2179340 Vibrio cholerae M66-2 7773269 YP_002810760.1 CDS znuB NC_012578.1 2179333 2180115 D zinc ABC transporter permease 2179333..2180115 Vibrio cholerae M66-2 7773270 YP_002810761.1 CDS sucD NC_012578.1 2180222 2181094 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(2180222..2181094) Vibrio cholerae M66-2 7773271 YP_002810762.1 CDS sucC NC_012578.1 2181094 2182260 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(2181094..2182260) Vibrio cholerae M66-2 7773272 YP_002810763.1 CDS sucB NC_012578.1 2182428 2183642 R component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase complement(2182428..2183642) Vibrio cholerae M66-2 7773273 YP_002810764.1 CDS sucA NC_012578.1 2183671 2186481 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component complement(2183671..2186481) Vibrio cholerae M66-2 7773274 YP_002810765.1 CDS sdhB NC_012578.1 2186570 2187280 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit complement(2186570..2187280) Vibrio cholerae M66-2 7773275 YP_002810766.1 CDS sdhA NC_012578.1 2187295 2189061 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit complement(2187295..2189061) Vibrio cholerae M66-2 7773276 YP_002810767.1 CDS sdhD NC_012578.1 2189062 2189406 R succinate dehydrogenase, hydrophobic membrane anchor protein complement(2189062..2189406) Vibrio cholerae M66-2 7773277 YP_002810768.1 CDS sdhC NC_012578.1 2189400 2189792 R succinate dehydrogenase cytochrome b556 large membrane subunit complement(2189400..2189792) Vibrio cholerae M66-2 7773278 YP_002810769.1 CDS gltA NC_012578.1 2190182 2191477 D type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 2190182..2191477 Vibrio cholerae M66-2 7773279 YP_002810770.1 CDS VCM66_2017 NC_012578.1 2191529 2192299 R hypothetical protein complement(2191529..2192299) Vibrio cholerae M66-2 7773280 YP_002810771.1 CDS VCM66_2018 NC_012578.1 2192352 2193125 D hypothetical protein 2192352..2193125 Vibrio cholerae M66-2 7773281 YP_002810772.1 CDS pgm NC_012578.1 2193175 2194821 R catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase complement(2193175..2194821) Vibrio cholerae M66-2 7773282 YP_002810773.1 CDS seqA NC_012578.1 2194930 2195463 R negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA complement(2194930..2195463) Vibrio cholerae M66-2 7773283 YP_002810774.1 CDS VCM66_2021 NC_012578.1 2195556 2196329 D putative esterase/lipase 2195556..2196329 Vibrio cholerae M66-2 7773284 YP_002810775.1 CDS VCM66_2022 NC_012578.1 2196425 2196646 D hypothetical protein 2196425..2196646 Vibrio cholerae M66-2 7773285 YP_002810776.1 CDS fldA NC_012578.1 2196695 2197222 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 2196695..2197222 Vibrio cholerae M66-2 7773286 YP_002810777.1 CDS VCM66_2024 NC_012578.1 2197296 2197985 R hypothetical protein complement(2197296..2197985) Vibrio cholerae M66-2 7773287 YP_002810778.1 CDS VCM66_2025 NC_012578.1 2197991 2198431 R hypothetical protein complement(2197991..2198431) Vibrio cholerae M66-2 7773288 YP_002810779.1 CDS VCM66_2026 NC_012578.1 2198394 2198531 R hypothetical protein complement(2198394..2198531) Vibrio cholerae M66-2 7773289 YP_002810780.1 CDS VCM66_2027 NC_012578.1 2198547 2199425 D LysR family transcriptional regulator 2198547..2199425 Vibrio cholerae M66-2 7773290 YP_002810781.1 CDS VCM66_2028 NC_012578.1 2199429 2199929 R hypothetical protein complement(2199429..2199929) Vibrio cholerae M66-2 7773291 YP_002810782.1 CDS fur NC_012578.1 2200295 2200747 D negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 2200295..2200747 Vibrio cholerae M66-2 7773292 YP_002810783.1 CDS VCM66_2030 NC_012578.1 2200829 2201845 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(2200829..2201845) Vibrio cholerae M66-2 7773293 YP_002810784.1 CDS pdxB NC_012578.1 2201826 2202989 R erythronate-4-phosphate dehydrogenase complement(2201826..2202989) Vibrio cholerae M66-2 7773294 YP_002810785.1 CDS fabB NC_012578.1 2203175 2204386 R 3-oxoacyl-ACP synthase I complement(2203175..2204386) Vibrio cholerae M66-2 7773295 YP_002810786.1 CDS mnmC NC_012578.1 2204504 2206528 D catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 2204504..2206528 Vibrio cholerae M66-2 7773296 YP_002810787.1 CDS VCM66_2034 NC_012578.1 2206607 2207134 R hypothetical protein complement(2206607..2207134) Vibrio cholerae M66-2 7773297 YP_002810788.1 CDS VCM66_2035 NC_012578.1 2207342 2207605 R hypothetical protein complement(2207342..2207605) Vibrio cholerae M66-2 7773298 YP_002810789.1 CDS VCM66_2036 NC_012578.1 2207644 2208174 R hypothetical protein complement(2207644..2208174) Vibrio cholerae M66-2 7773299 YP_002810790.1 CDS VCM66_2037 NC_012578.1 2208365 2208481 R hypothetical protein complement(2208365..2208481) Vibrio cholerae M66-2 7773300 YP_002810791.1 CDS VCM66_2038 NC_012578.1 2208538 2209161 D hypothetical protein 2208538..2209161 Vibrio cholerae M66-2 7773301 YP_002810792.1 CDS aroC NC_012578.1 2209243 2210328 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2209243..2210328) Vibrio cholerae M66-2 7773302 YP_002810793.1 CDS VCM66_2040 NC_012578.1 2210426 2210650 D hypothetical protein 2210426..2210650 Vibrio cholerae M66-2 7773303 YP_002810794.1 CDS VCM66_2041 NC_012578.1 2210558 2211502 R involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(2210558..2211502) Vibrio cholerae M66-2 7773304 YP_002810795.1 CDS VCM66_2042 NC_012578.1 2211557 2212117 D hypothetical protein 2211557..2212117 Vibrio cholerae M66-2 7773305 YP_002810796.1 CDS flhB NC_012578.1 2212125 2213255 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(2212125..2213255) Vibrio cholerae M66-2 7773306 YP_002810797.1 CDS fliR NC_012578.1 2213265 2214047 R FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR complement(2213265..2214047) Vibrio cholerae M66-2 7773307 YP_002810798.1 CDS fliQ NC_012578.1 2214056 2214325 R with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ complement(2214056..2214325) Vibrio cholerae M66-2 7773308 YP_002810799.1 CDS fliP NC_012578.1 2214338 2215237 R FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP complement(2214338..2215237) Vibrio cholerae M66-2 7773309 YP_002810800.1 CDS fliO NC_012578.1 2215215 2215604 R flagellar protein FliO complement(2215215..2215604) Vibrio cholerae M66-2 7773310 YP_002810801.1 CDS fliN NC_012578.1 2215608 2216024 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein complement(2215608..2216024) Vibrio cholerae M66-2 7773311 YP_002810802.1 CDS fliM NC_012578.1 2216089 2217138 R with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM complement(2216089..2217138) Vibrio cholerae M66-2 7773312 YP_002810803.1 CDS fliL NC_012578.1 2217146 2217649 R interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL complement(2217146..2217649) Vibrio cholerae M66-2 7773313 YP_002810804.1 CDS VCM66_2051 NC_012578.1 2217684 2219708 R putative flagellar hook-length control protein FliK complement(2217684..2219708) Vibrio cholerae M66-2 7773314 YP_002810805.1 CDS fliJ NC_012578.1 2219872 2220315 R rod/hook and filament chaperone; flagellar biosynthesis chaperone complement(2219872..2220315) Vibrio cholerae M66-2 7773315 YP_002810806.1 CDS fliI NC_012578.1 2220330 2221649 R involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase complement(2220330..2221649) Vibrio cholerae M66-2 7773316 YP_002810807.1 CDS fliH NC_012578.1 2221653 2222465 R binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H complement(2221653..2222465) Vibrio cholerae M66-2 7773317 YP_002810808.1 CDS fliG NC_012578.1 2222546 2223592 R One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G complement(2222546..2223592) Vibrio cholerae M66-2 7773318 YP_002810809.1 CDS fliF NC_012578.1 2223585 2225327 R the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein complement(2223585..2225327) Vibrio cholerae M66-2 7773319 YP_002810810.1 CDS fliE NC_012578.1 2225343 2225672 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(2225343..2225672) Vibrio cholerae M66-2 7773320 YP_002810811.1 CDS flrC NC_012578.1 2225730 2227169 R flagellar regulatory protein C complement(2225730..2227169) Vibrio cholerae M66-2 7773321 YP_002810812.1 CDS flrB NC_012578.1 2227166 2228221 R flagellar regulatory protein B complement(2227166..2228221) Vibrio cholerae M66-2 7773322 YP_002810813.1 CDS flrA NC_012578.1 2228333 2229790 R flagellar regulatory protein A complement(2228333..2229790) Vibrio cholerae M66-2 7773323 YP_002810814.1 CDS fliS NC_012578.1 2230022 2230432 R flagellin specific chaperone; flagellar protein FliS complement(2230022..2230432) Vibrio cholerae M66-2 7773324 YP_002810815.1 CDS VCM66_2062 NC_012578.1 2230443 2230757 R putative flagellar rod protein FlaI complement(2230443..2230757) Vibrio cholerae M66-2 7773325 YP_002810816.1 CDS fliD NC_012578.1 2230750 2232750 R involved in flagellin assembly; flagellar capping protein complement(2230750..2232750) Vibrio cholerae M66-2 7773326 YP_002810817.1 CDS flaG NC_012578.1 2232772 2233233 R possibly involved in flagella export; flagellar protein FlaG complement(2232772..2233233) Vibrio cholerae M66-2 7773327 YP_002810818.1 CDS flaB NC_012578.1 2233307 2234437 R structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus; flagellin complement(2233307..2234437) Vibrio cholerae M66-2 7773328 YP_002810819.1 CDS flaD NC_012578.1 2234673 2235806 R structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus; flagellin complement(2234673..2235806) Vibrio cholerae M66-2 7773329 YP_002810820.1 CDS flaE NC_012578.1 2236096 2237232 R structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus; flagellin complement(2236096..2237232) Vibrio cholerae M66-2 7773330 YP_002810821.1 CDS VCM66_2068 NC_012578.1 2237356 2238264 R tyrA protein complement(2237356..2238264) Vibrio cholerae M66-2 7773331 YP_002810822.1 CDS VCM66_2069 NC_012578.1 2238330 2238794 R hypothetical protein complement(2238330..2238794) Vibrio cholerae M66-2 7773332 YP_002810823.1 CDS VCM66_2070 NC_012578.1 2238938 2239294 D hypothetical protein 2238938..2239294 Vibrio cholerae M66-2 7773333 YP_002810824.1 CDS VCM66_2071 NC_012578.1 2239270 2239368 R hypothetical protein complement(2239270..2239368) Vibrio cholerae M66-2 7773334 YP_002810825.1 CDS VCM66_2072 NC_012578.1 2239361 2239648 R hypothetical protein complement(2239361..2239648) Vibrio cholerae M66-2 7773335 YP_002810826.1 CDS VCM66_2073 NC_012578.1 2239851 2240246 D hypothetical protein 2239851..2240246 Vibrio cholerae M66-2 7773336 YP_002810827.1 CDS VCM66_2074 NC_012578.1 2240212 2240307 R hypothetical protein complement(2240212..2240307) Vibrio cholerae M66-2 7773337 YP_002810828.1 CDS dapE NC_012578.1 2240277 2241410 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 2240277..2241410 Vibrio cholerae M66-2 7773338 YP_002810829.1 CDS VCM66_2076 NC_012578.1 2241338 2242087 D D,D-carboxypeptidase-like protein 2241338..2242087 Vibrio cholerae M66-2 7773339 YP_002810830.1 CDS VCM66_2077 NC_012578.1 2242077 2242301 D hypothetical protein 2242077..2242301 Vibrio cholerae M66-2 7773340 YP_002810831.1 CDS VCM66_2078 NC_012578.1 2242285 2242380 R hypothetical protein complement(2242285..2242380) Vibrio cholerae M66-2 7773341 YP_002810832.1 CDS nlpB NC_012578.1 2242394 2243413 R lipoprotein complement(2242394..2243413) Vibrio cholerae M66-2 7773342 YP_002810833.1 CDS dapA NC_012578.1 2243471 2244349 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(2243471..2244349) Vibrio cholerae M66-2 7773343 YP_002810834.1 CDS VCM66_2081 NC_012578.1 2244513 2244617 D hypothetical protein 2244513..2244617 Vibrio cholerae M66-2 7773344 YP_002810835.1 CDS VCM66_2082 NC_012578.1 2244627 2245169 D putative glycine cleavage system transcriptional repressor 2244627..2245169 Vibrio cholerae M66-2 7773345 YP_002810836.1 CDS bcp NC_012578.1 2245184 2245651 D bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 2245184..2245651 Vibrio cholerae M66-2 7773346 YP_002810837.1 CDS VCM66_2084 NC_012578.1 2245753 2247624 R methyl-accepting chemotaxis protein complement(2245753..2247624) Vibrio cholerae M66-2 7773347 YP_002810838.1 CDS VCM66_2085 NC_012578.1 2247815 2248879 R putative permease PerM complement(2247815..2248879) Vibrio cholerae M66-2 7773348 YP_002810839.1 CDS VCM66_2086 NC_012578.1 2248872 2249108 R hypothetical protein complement(2248872..2249108) Vibrio cholerae M66-2 7773349 YP_002810840.1 CDS VCM66_2087 NC_012578.1 2249292 2250746 D hypothetical protein 2249292..2250746 Vibrio cholerae M66-2 7773350 YP_002810841.1 CDS arsC NC_012578.1 2250769 2251119 D arsenate reductase 2250769..2251119 Vibrio cholerae M66-2 7773351 YP_002810842.1 CDS wrbA NC_012578.1 2251116 2251676 D Trp repressor-binding protein 2251116..2251676 Vibrio cholerae M66-2 7773352 YP_002810843.1 CDS VCM66_2090 NC_012578.1 2251679 2252116 D hypothetical protein 2251679..2252116 Vibrio cholerae M66-2 7773353 YP_002810844.1 CDS VCM66_2091 NC_012578.1 2252323 2253471 R hypothetical protein complement(2252323..2253471) Vibrio cholerae M66-2 7773354 YP_002810845.1 CDS VCM66_2092 NC_012578.1 2253525 2253635 R hypothetical protein complement(2253525..2253635) Vibrio cholerae M66-2 7773355 YP_002810846.1 CDS VCM66_2093 NC_012578.1 2253608 2253718 R hypothetical protein complement(2253608..2253718) Vibrio cholerae M66-2 7773356 YP_002810847.1 CDS uraA NC_012578.1 2253692 2254945 D uracil permease 2253692..2254945 Vibrio cholerae M66-2 7773357 YP_002810848.1 CDS VCM66_2095 NC_012578.1 2255016 2255498 R hypothetical protein complement(2255016..2255498) Vibrio cholerae M66-2 7773358 YP_002810849.1 CDS VCM66_2096 NC_012578.1 2255512 2255625 R hypothetical protein complement(2255512..2255625) Vibrio cholerae M66-2 7773359 YP_002810850.1 CDS ushA NC_012578.1 2255632 2257293 R catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase complement(2255632..2257293) Vibrio cholerae M66-2 7773360 YP_002810851.1 CDS kdsA NC_012578.1 2257835 2258686 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(2257835..2258686) Vibrio cholerae M66-2 7773361 YP_002810852.1 CDS VCM66_2099 NC_012578.1 2258706 2259518 R hypothetical protein complement(2258706..2259518) Vibrio cholerae M66-2 7773362 YP_002810853.1 CDS VCM66_2100 NC_012578.1 2259534 2259917 R hypothetical protein complement(2259534..2259917) Vibrio cholerae M66-2 7773363 YP_002810854.1 CDS hemK NC_012578.1 2259917 2260777 R hemK protein complement(2259917..2260777) Vibrio cholerae M66-2 7773364 YP_002810855.1 CDS prfA NC_012578.1 2260781 2261869 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(2260781..2261869) Vibrio cholerae M66-2 7773365 YP_002810856.1 CDS hemA NC_012578.1 2261899 2263158 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(2261899..2263158) Vibrio cholerae M66-2 7773366 YP_002810857.1 CDS lolB NC_012578.1 2263299 2263934 D Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 2263299..2263934 Vibrio cholerae M66-2 7773367 YP_002810858.1 CDS ipk NC_012578.1 2263916 2264803 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2263916..2264803 Vibrio cholerae M66-2 7773368 YP_002810859.1 CDS prsA NC_012578.1 2264834 2265778 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 2264834..2265778 Vibrio cholerae M66-2 7773369 YP_002810860.1 CDS pth NC_012578.1 2265947 2266537 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 2265947..2266537 Vibrio cholerae M66-2 7773370 YP_002810861.1 CDS VCM66_2108 NC_012578.1 2266488 2267639 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 2266488..2267639 Vibrio cholerae M66-2 7773371 YP_002810862.1 CDS flaC NC_012578.1 2269979 2271112 R structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus; flagellin complement(2269979..2271112) Vibrio cholerae M66-2 7774042 YP_002810863.1 CDS flaA NC_012578.1 2271667 2272806 R structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus; flagellin complement(2271667..2272806) Vibrio cholerae M66-2 7773373 YP_002810864.1 CDS VCM66_2112 NC_012578.1 2272955 2273134 R hypothetical protein complement(2272955..2273134) Vibrio cholerae M66-2 7773374 YP_002810865.1 CDS flgL NC_012578.1 2273214 2274407 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes.; flagellar hook-associated protein FlgL complement(2273214..2274407) Vibrio cholerae M66-2 7773375 YP_002810866.1 CDS flgK NC_012578.1 2274420 2276294 R with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK complement(2274420..2276294) Vibrio cholerae M66-2 7773376 YP_002810867.1 CDS flgJ NC_012578.1 2276474 2277412 R Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ complement(2276474..2277412) Vibrio cholerae M66-2 7773377 YP_002810868.1 CDS flgI NC_012578.1 2277423 2278508 R part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein complement(2277423..2278508) Vibrio cholerae M66-2 7773378 YP_002810869.1 CDS flgH NC_012578.1 2278599 2279384 R part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein complement(2278599..2279384) Vibrio cholerae M66-2 7773379 YP_002810870.1 CDS flgG NC_012578.1 2279399 2280187 R makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG complement(2279399..2280187) Vibrio cholerae M66-2 7773380 YP_002810871.1 CDS flgF NC_012578.1 2280207 2280956 R FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF complement(2280207..2280956) Vibrio cholerae M66-2 7773381 YP_002810872.1 CDS flgE NC_012578.1 2281139 2282443 R the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE complement(2281139..2282443) Vibrio cholerae M66-2 7773382 YP_002810873.1 CDS flgD NC_012578.1 2282472 2283179 R acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein complement(2282472..2283179) Vibrio cholerae M66-2 7773383 YP_002810874.1 CDS flgC NC_012578.1 2283197 2283613 R with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC complement(2283197..2283613) Vibrio cholerae M66-2 7773384 YP_002810875.1 CDS flgB NC_012578.1 2283618 2284013 R with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB complement(2283618..2284013) Vibrio cholerae M66-2 7773385 YP_002810876.1 CDS cheR-2 NC_012578.1 2284233 2285060 R chemotaxis protein methyltransferase CheR complement(2284233..2285060) Vibrio cholerae M66-2 7773386 YP_002810877.1 CDS cheV-3 NC_012578.1 2285071 2285997 R chemotaxis protein CheV complement(2285071..2285997) Vibrio cholerae M66-2 7773387 YP_002810878.1 CDS flgA NC_012578.1 2286054 2286821 D required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 2286054..2286821 Vibrio cholerae M66-2 7773388 YP_002810879.1 CDS VCM66_2127 NC_012578.1 2286952 2287275 D putative negative regulator of flagellin synthesis FlgM 2286952..2287275 Vibrio cholerae M66-2 7773389 YP_002810880.1 CDS VCM66_2128 NC_012578.1 2287373 2287804 D hypothetical protein 2287373..2287804 Vibrio cholerae M66-2 7773390 YP_002810881.1 CDS VCM66_2129 NC_012578.1 2287914 2288351 R hypothetical protein complement(2287914..2288351) Vibrio cholerae M66-2 7773391 YP_002810882.1 CDS VCM66_2130 NC_012578.1 2288359 2289027 R hypothetical protein complement(2288359..2289027) Vibrio cholerae M66-2 7773392 YP_002810883.1 CDS VCM66_2131 NC_012578.1 2289155 2290288 D hypothetical protein 2289155..2290288 Vibrio cholerae M66-2 7773393 YP_002810884.1 CDS vibF NC_012578.1 2290418 2297659 R nonribosomal peptide synthetase VibF complement(2290418..2297659) Vibrio cholerae M66-2 7773394 YP_002810885.1 CDS viuB NC_012578.1 2297917 2298732 R vibriobactin utilization protein ViuB complement(2297917..2298732) Vibrio cholerae M66-2 7773395 YP_002810886.1 CDS viuA NC_012578.1 2299036 2301099 R ferric vibriobactin receptor complement(2299036..2301099) Vibrio cholerae M66-2 7773396 YP_002810887.1 CDS VCM66_2135 NC_012578.1 2301519 2302217 D hypothetical protein 2301519..2302217 Vibrio cholerae M66-2 7773397 YP_002810888.1 CDS ompA NC_012578.1 2302306 2303271 R outer membrane protein OmpA complement(2302306..2303271) Vibrio cholerae M66-2 7773398 YP_002810889.1 CDS gltX NC_012578.1 2303567 2305096 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2303567..2305096) Vibrio cholerae M66-2 7773399 YP_002810890.1 CDS VCM66_2138 NC_012578.1 2305165 2307912 D cation transport ATPase, E1-E2 family 2305165..2307912 Vibrio cholerae M66-2 7773400 YP_002810891.1 CDS VCM66_2139 NC_012578.1 2307909 2308361 D hypothetical protein 2307909..2308361 Vibrio cholerae M66-2 7773401 YP_002810892.1 CDS chb-2 NC_012578.1 2308498 2311149 R beta-N-acetylhexosaminidase complement(2308498..2311149) Vibrio cholerae M66-2 7773402 YP_002810893.1 CDS VCM66_2141 NC_012578.1 2311182 2311295 D hypothetical protein 2311182..2311295 Vibrio cholerae M66-2 7773403 YP_002810894.1 CDS VCM66_2142 NC_012578.1 2311377 2311493 R hypothetical protein complement(2311377..2311493) Vibrio cholerae M66-2 7773404 YP_002810895.1 CDS VCM66_2143 NC_012578.1 2311566 2312462 D hypothetical protein 2311566..2312462 Vibrio cholerae M66-2 7773405 YP_002810896.1 CDS VCM66_2144 NC_012578.1 2312943 2313083 D hypothetical protein 2312943..2313083 Vibrio cholerae M66-2 7774061 YP_002810897.1 CDS VCM66_2145 NC_012578.1 2313265 2313843 D hypothetical protein 2313265..2313843 Vibrio cholerae M66-2 7773407 YP_002810898.1 CDS VCM66_2146 NC_012578.1 2313873 2314895 D pseudouridine synthase family 1 protein 2313873..2314895 Vibrio cholerae M66-2 7773408 YP_002810899.1 CDS VCM66_2147 NC_012578.1 2314993 2316531 R GGDEF family protein complement(2314993..2316531) Vibrio cholerae M66-2 7773409 YP_002810900.1 CDS upp NC_012578.1 2316762 2317388 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(2316762..2317388) Vibrio cholerae M66-2 7773410 YP_002810901.1 CDS purM NC_012578.1 2317555 2318595 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 2317555..2318595 Vibrio cholerae M66-2 7773411 YP_002810902.1 CDS purN NC_012578.1 2318598 2319236 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 2318598..2319236 Vibrio cholerae M66-2 7773412 YP_002810903.1 CDS VCM66_2151 NC_012578.1 2319255 2319362 D hypothetical protein 2319255..2319362 Vibrio cholerae M66-2 7773413 YP_002810904.1 CDS VCM66_2152 NC_012578.1 2319377 2320222 R hypothetical protein complement(2319377..2320222) Vibrio cholerae M66-2 7773414 YP_002810905.1 CDS gmhA NC_012578.1 2320285 2320860 R catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase complement(2320285..2320860) Vibrio cholerae M66-2 7773415 YP_002810906.1 CDS fadE NC_012578.1 2321178 2323622 D functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 2321178..2323622 Vibrio cholerae M66-2 7773416 YP_002810907.1 CDS VCM66_2155 NC_012578.1 2323769 2325028 R hypothetical protein complement(2323769..2325028) Vibrio cholerae M66-2 7773417 YP_002810908.1 CDS dnaQ NC_012578.1 2325037 2325780 R 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon complement(2325037..2325780) Vibrio cholerae M66-2 7773418 YP_002810909.1 CDS rnhA NC_012578.1 2325837 2326307 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 2325837..2326307 Vibrio cholerae M66-2 7773419 YP_002810910.1 CDS VCM66_2158 NC_012578.1 2326378 2327115 R hypothetical protein complement(2326378..2327115) Vibrio cholerae M66-2 7773420 YP_002810911.1 CDS VCM66_2159 NC_012578.1 2327153 2327911 D putative hydroxyacylglutathione hydrolase GloB 2327153..2327911 Vibrio cholerae M66-2 7773421 YP_002810912.1 CDS mltD NC_012578.1 2327983 2329581 D membrane-bound lytic murein transglycosylase D 2327983..2329581 Vibrio cholerae M66-2 7773422 YP_002810913.1 CDS VCM66_2161 NC_012578.1 2329598 2330443 R hypothetical protein complement(2329598..2330443) Vibrio cholerae M66-2 7773423 YP_002810914.1 CDS glnB-2 NC_012578.1 2330511 2330855 R nitrogen regulatory protein P-II complement(2330511..2330855) Vibrio cholerae M66-2 7773424 YP_002810915.1 CDS VCM66_2163 NC_012578.1 2331009 2331533 R decarboxylase complement(2331009..2331533) Vibrio cholerae M66-2 7773425 YP_002810916.1 CDS VCM66_2164 NC_012578.1 2331910 2332233 R cytochrome c554 complement(2331910..2332233) Vibrio cholerae M66-2 7773426 YP_002810917.1 CDS tilS NC_012578.1 2332269 2333591 R tRNA(Ile)-lysidine synthetase complement(2332269..2333591) Vibrio cholerae M66-2 7773427 YP_002810918.1 CDS VCM66_2166 NC_012578.1 2333559 2333663 D hypothetical protein 2333559..2333663 Vibrio cholerae M66-2 7773428 YP_002810919.1 CDS accA NC_012578.1 2333731 2334690 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(2333731..2334690) Vibrio cholerae M66-2 7773429 YP_002810920.1 CDS dnaE NC_012578.1 2334745 2338239 R catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha complement(2334745..2338239) Vibrio cholerae M66-2 7773430 YP_002810921.1 CDS rnhB NC_012578.1 2338263 2338883 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(2338263..2338883) Vibrio cholerae M66-2 7773431 YP_002810922.1 CDS lpxB NC_012578.1 2338908 2340047 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase complement(2338908..2340047) Vibrio cholerae M66-2 7773432 YP_002810923.1 CDS lpxA NC_012578.1 2340208 2340996 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(2340208..2340996) Vibrio cholerae M66-2 7773433 YP_002810924.1 CDS fabZ NC_012578.1 2340998 2341459 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(2340998..2341459) Vibrio cholerae M66-2 7773434 YP_002810925.1 CDS lpxD NC_012578.1 2341535 2342590 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(2341535..2342590) Vibrio cholerae M66-2 7773435 YP_002810926.1 CDS ompH NC_012578.1 2342600 2343109 R outer membrane protein OmpH complement(2342600..2343109) Vibrio cholerae M66-2 7773436 YP_002810927.1 CDS VCM66_2175 NC_012578.1 2343124 2345535 R part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT complement(2343124..2345535) Vibrio cholerae M66-2 7773437 YP_002810928.1 CDS VCM66_2176 NC_012578.1 2345584 2346942 R hypothetical protein complement(2345584..2346942) Vibrio cholerae M66-2 7773438 YP_002810929.1 CDS dxr NC_012578.1 2346939 2348147 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(2346939..2348147) Vibrio cholerae M66-2 7773439 YP_002810930.1 CDS cdsA NC_012578.1 2348196 2349038 R phosphatidate cytidylyltransferase complement(2348196..2349038) Vibrio cholerae M66-2 7773440 YP_002810931.1 CDS uppS NC_012578.1 2349056 2349826 R UDP diphosphate synthase complement(2349056..2349826) Vibrio cholerae M66-2 7773441 YP_002810932.1 CDS frr NC_012578.1 2349900 2350457 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(2349900..2350457) Vibrio cholerae M66-2 7773442 YP_002810933.1 CDS pyrH NC_012578.1 2350511 2351242 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(2350511..2351242) Vibrio cholerae M66-2 7773443 YP_002810934.1 CDS tsf NC_012578.1 2351430 2352272 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(2351430..2352272) Vibrio cholerae M66-2 7773444 YP_002810935.1 CDS rpsB NC_012578.1 2352404 2353132 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(2352404..2353132) Vibrio cholerae M66-2 7773445 YP_002810936.1 CDS map NC_012578.1 2353473 2354315 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 2353473..2354315 Vibrio cholerae M66-2 7773446 YP_002810937.1 CDS glnD NC_012578.1 2354405 2357050 D catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 2354405..2357050 Vibrio cholerae M66-2 7773447 YP_002810938.1 CDS VCM66_2186 NC_012578.1 2357125 2357223 R hypothetical protein complement(2357125..2357223) Vibrio cholerae M66-2 7773448 YP_002810939.1 CDS VCM66_2187 NC_012578.1 2357296 2357709 D hypothetical protein 2357296..2357709 Vibrio cholerae M66-2 7773449 YP_002810940.1 CDS pgpA NC_012578.1 2357750 2358259 R hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A complement(2357750..2358259) Vibrio cholerae M66-2 7773450 YP_002810941.1 CDS thiL NC_012578.1 2358256 2359260 R catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase complement(2358256..2359260) Vibrio cholerae M66-2 7773451 YP_002810942.1 CDS nusB NC_012578.1 2359321 2359791 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(2359321..2359791) Vibrio cholerae M66-2 7773452 YP_002810943.1 CDS ribH NC_012578.1 2359791 2360312 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(2359791..2360312) Vibrio cholerae M66-2 7773453 YP_002810944.1 CDS ribB/A NC_012578.1 2360526 2361635 R 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II complement(2360526..2361635) Vibrio cholerae M66-2 7773454 YP_002810945.1 CDS ribC NC_012578.1 2361676 2362329 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(2361676..2362329) Vibrio cholerae M66-2 7773455 YP_002810946.1 CDS ribD NC_012578.1 2362334 2363437 R riboflavin biosynthesis protein RibD complement(2362334..2363437) Vibrio cholerae M66-2 7773456 YP_002810947.1 CDS nrdR NC_012578.1 2363463 2363933 R transcriptional regulator NrdR complement(2363463..2363933) Vibrio cholerae M66-2 7773457 YP_002810948.1 CDS proA NC_012578.1 2364012 2365265 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(2364012..2365265) Vibrio cholerae M66-2 7773458 YP_002810949.1 CDS proB NC_012578.1 2365274 2366464 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(2365274..2366464) Vibrio cholerae M66-2 7773459 YP_002810950.1 CDS crl NC_012578.1 2366528 2366917 R involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl complement(2366528..2366917) Vibrio cholerae M66-2 7773460 YP_002810951.1 CDS frsA NC_012578.1 2367051 2368298 R forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein complement(2367051..2368298) Vibrio cholerae M66-2 7773461 YP_002810952.1 CDS gpt NC_012578.1 2368395 2368859 R catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase complement(2368395..2368859) Vibrio cholerae M66-2 7773462 YP_002810953.1 CDS VCM66_2201 NC_012578.1 2368897 2370189 R hypothetical protein complement(2368897..2370189) Vibrio cholerae M66-2 7773463 YP_002810954.1 CDS pepD NC_012578.1 2370936 2372540 D aminoacyl-histidine dipeptidase 2370936..2372540 Vibrio cholerae M66-2 7773464 YP_002810955.1 CDS VCM66_2203 NC_012578.1 2372774 2373217 D Ribosomal protein S6 modification protein 2372774..2373217 Vibrio cholerae M66-2 7773465 YP_002810956.1 CDS rimK NC_012578.1 2373214 2374119 D ribosomal protein S6 modification protein 2373214..2374119 Vibrio cholerae M66-2 7773466 YP_002810957.1 CDS VCM66_2205 NC_012578.1 2374079 2375167 D hypothetical protein 2374079..2375167 Vibrio cholerae M66-2 7773467 YP_002810958.1 CDS VCM66_2206 NC_012578.1 2375236 2376591 R sodium-dependent transporter complement(2375236..2376591) Vibrio cholerae M66-2 7773468 YP_002810959.1 CDS VCM66_2207 NC_012578.1 2376650 2376751 D hypothetical protein 2376650..2376751 Vibrio cholerae M66-2 7773469 YP_002810960.1 CDS VCM66_2208 NC_012578.1 2376748 2378265 R GGDEF family protein complement(2376748..2378265) Vibrio cholerae M66-2 7773470 YP_002810961.1 CDS VCM66_2209 NC_012578.1 2378329 2379099 R hypothetical protein complement(2378329..2379099) Vibrio cholerae M66-2 7773471 YP_002810962.1 CDS dinP NC_012578.1 2379345 2380427 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(2379345..2380427) Vibrio cholerae M66-2 7773472 YP_002810963.1 CDS VCM66_2211 NC_012578.1 2380536 2380769 R hypothetical protein complement(2380536..2380769) Vibrio cholerae M66-2 7773473 YP_002810964.1 CDS apbE NC_012578.1 2380786 2381889 R thiamin biosynthesis lipoprotein ApbE complement(2380786..2381889) Vibrio cholerae M66-2 7773474 YP_002810965.1 CDS nqrF NC_012578.1 2381936 2383162 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F complement(2381936..2383162) Vibrio cholerae M66-2 7773475 YP_002810966.1 CDS nqrE NC_012578.1 2383196 2383792 R Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E complement(2383196..2383792) Vibrio cholerae M66-2 7773476 YP_002810967.1 CDS nqrD NC_012578.1 2383800 2384432 R Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D complement(2383800..2384432) Vibrio cholerae M66-2 7773477 YP_002810968.1 CDS nqrC NC_012578.1 2384432 2385205 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C complement(2384432..2385205) Vibrio cholerae M66-2 7773478 YP_002810969.1 CDS nqrB NC_012578.1 2385192 2386475 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B complement(2385192..2386475) Vibrio cholerae M66-2 7773479 YP_002810970.1 CDS nqrA NC_012578.1 2386445 2387833 R uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A complement(2386445..2387833) Vibrio cholerae M66-2 7773480 YP_002810971.1 CDS bolA NC_012578.1 2388270 2388590 R bolA protein complement(2388270..2388590) Vibrio cholerae M66-2 7773481 YP_002810972.1 CDS VCM66_2220 NC_012578.1 2388635 2389885 D Putative ribosomal RNA small subunit methyltransferase D 2388635..2389885 Vibrio cholerae M66-2 7773482 YP_002810973.1 CDS VCM66_2221 NC_012578.1 2389882 2390502 D putative lipoprotein 2389882..2390502 Vibrio cholerae M66-2 7773483 YP_002810974.1 CDS ppiA NC_012578.1 2390459 2391043 D peptidyl-prolyl cis-trans isomerase A 2390459..2391043 Vibrio cholerae M66-2 7773484 YP_002810975.1 CDS VCM66_2223 NC_012578.1 2391112 2392500 D putative ampG protein 2391112..2392500 Vibrio cholerae M66-2 7773485 YP_002810976.1 CDS VCM66_2224 NC_012578.1 2392588 2393268 R putative transcriptional activator complement(2392588..2393268) Vibrio cholerae M66-2 7773486 YP_002810977.1 CDS VCM66_2225 NC_012578.1 2393265 2393849 R Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor complement(2393265..2393849) Vibrio cholerae M66-2 7773487 YP_002810978.1 CDS VCM66_2226 NC_012578.1 2393940 2394521 R hypothetical protein complement(2393940..2394521) Vibrio cholerae M66-2 7773488 YP_002810979.1 CDS VCM66_2227 NC_012578.1 2394590 2394700 D hypothetical protein 2394590..2394700 Vibrio cholerae M66-2 7773489 YP_002810980.1 CDS ompK NC_012578.1 2394759 2395649 D outer membrane protein OmpK 2394759..2395649 Vibrio cholerae M66-2 7773490 YP_002810981.1 CDS VCM66_2229 NC_012578.1 2395646 2395738 R hypothetical protein complement(2395646..2395738) Vibrio cholerae M66-2 7773491 YP_002810982.1 CDS panE NC_012578.1 2395788 2396678 D ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 2395788..2396678 Vibrio cholerae M66-2 7773492 YP_002810983.1 CDS thiJ NC_012578.1 2396663 2397280 D 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis protein 2396663..2397280 Vibrio cholerae M66-2 7773493 YP_002810984.1 CDS VCM66_2232 NC_012578.1 2397264 2398478 D class V aminotransferase 2397264..2398478 Vibrio cholerae M66-2 7773494 YP_002810985.1 CDS VCM66_2233 NC_012578.1 2398548 2398982 R SufE-like protein complement(2398548..2398982) Vibrio cholerae M66-2 7773495 YP_002810986.1 CDS VCM66_2234 NC_012578.1 2398987 2399808 R HesA/MoeB/ThiF family protein complement(2398987..2399808) Vibrio cholerae M66-2 7773496 YP_002810987.1 CDS mltA NC_012578.1 2399900 2401006 R membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A complement(2399900..2401006) Vibrio cholerae M66-2 7773497 YP_002810988.1 CDS VCM66_2236 NC_012578.1 2400970 2401080 D hypothetical protein 2400970..2401080 Vibrio cholerae M66-2 7773498 YP_002810989.1 CDS VCM66_2237 NC_012578.1 2401077 2401481 R hypothetical protein complement(2401077..2401481) Vibrio cholerae M66-2 7773499 YP_002810990.1 CDS VCM66_2238 NC_012578.1 2401530 2401625 R hypothetical protein complement(2401530..2401625) Vibrio cholerae M66-2 7773500 YP_002810991.1 CDS argA NC_012578.1 2401717 2403087 D catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 2401717..2403087 Vibrio cholerae M66-2 7773501 YP_002810992.1 CDS VCM66_2240 NC_012578.1 2403061 2403225 R hypothetical protein complement(2403061..2403225) Vibrio cholerae M66-2 7773502 YP_002810993.1 CDS VCM66_2241 NC_012578.1 2403314 2403499 D hypothetical protein 2403314..2403499 Vibrio cholerae M66-2 7773503 YP_002810994.1 CDS recD NC_012578.1 2403529 2405649 R exodeoxyribonuclease V, 67 kDa subunit complement(2403529..2405649) Vibrio cholerae M66-2 7773504 YP_002810995.1 CDS recB NC_012578.1 2405646 2409272 R exodeoxyribonuclease V, 135 kDa subunit complement(2405646..2409272) Vibrio cholerae M66-2 7773505 YP_002810996.1 CDS VCM66_2244 NC_012578.1 2409429 2409530 R hypothetical protein complement(2409429..2409530) Vibrio cholerae M66-2 7773506 YP_002810997.1 CDS recC NC_012578.1 2409537 2412983 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(2409537..2412983) Vibrio cholerae M66-2 7773507 YP_002810998.1 CDS VCM66_2246 NC_012578.1 2413222 2414190 R hypothetical protein complement(2413222..2414190) Vibrio cholerae M66-2 7773508 YP_002810999.1 CDS VCM66_2247 NC_012578.1 2414301 2415215 D LysR family transcriptional regulator 2414301..2415215 Vibrio cholerae M66-2 7773509 YP_002811000.1 CDS VCM66_2248 NC_012578.1 2415170 2415280 D hypothetical protein 2415170..2415280 Vibrio cholerae M66-2 7773510 YP_002811001.1 CDS VCM66_2249 NC_012578.1 2415331 2415639 D hypothetical protein 2415331..2415639 Vibrio cholerae M66-2 7773511 YP_002811002.1 CDS VCM66_2250 NC_012578.1 2415640 2415738 R hypothetical protein complement(2415640..2415738) Vibrio cholerae M66-2 7773512 YP_002811003.1 CDS VCM66_2251 NC_012578.1 2415933 2416064 D hypothetical protein 2415933..2416064 Vibrio cholerae M66-2 7773513 YP_002811004.1 CDS dapD NC_012578.1 2416046 2417077 D 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 2416046..2417077 Vibrio cholerae M66-2 7773514 YP_002811005.1 CDS VCM66_2253 NC_012578.1 2417159 2418403 R hypothetical protein complement(2417159..2418403) Vibrio cholerae M66-2 7773515 YP_002811006.1 CDS VCM66_2254 NC_012578.1 2418366 2418473 R hypothetical protein complement(2418366..2418473) Vibrio cholerae M66-2 7773516 YP_002811007.1 CDS VCM66_2255 NC_012578.1 2418506 2419597 R GNAT family acetyltransferase complement(2418506..2419597) Vibrio cholerae M66-2 7773517 YP_002811008.1 CDS VCM66_2256 NC_012578.1 2419802 2421253 D ribosomal protein S6 modification protein-like protein 2419802..2421253 Vibrio cholerae M66-2 7773518 YP_002811009.1 CDS VCM66_2257 NC_012578.1 2421443 2422426 D Zinc transport protein zntB 2421443..2422426 Vibrio cholerae M66-2 7773519 YP_002811010.1 CDS VCM66_2258 NC_012578.1 2422410 2422997 D hypothetical protein 2422410..2422997 Vibrio cholerae M66-2 7773520 YP_002811011.1 CDS VCM66_2259 NC_012578.1 2422994 2423338 R hypothetical protein complement(2422994..2423338) Vibrio cholerae M66-2 7773521 YP_002811012.1 CDS VCM66_2260 NC_012578.1 2423497 2424504 D LacI family transcriptional regulator 2423497..2424504 Vibrio cholerae M66-2 7773522 YP_002811013.1 CDS lacZ NC_012578.1 2424516 2427650 R forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase complement(2424516..2427650) Vibrio cholerae M66-2 7773523 YP_002811014.1 CDS VCM66_2262 NC_012578.1 2427973 2429115 D chromate resistance protein-like protein 2427973..2429115 Vibrio cholerae M66-2 7773524 YP_002811015.1 CDS VCM66_2263 NC_012578.1 2429251 2430405 D rpfG-type response regulator 2429251..2430405 Vibrio cholerae M66-2 7773525 YP_002811016.1 CDS VCM66_2264 NC_012578.1 2430605 2432296 D putative long-chain-fatty-acid--CoA ligase 2430605..2432296 Vibrio cholerae M66-2 7773526 YP_002811017.1 CDS fusA-2 NC_012578.1 2432410 2434497 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(2432410..2434497) Vibrio cholerae M66-2 7773527 YP_002811018.1 CDS radA NC_012578.1 2434768 2436147 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(2434768..2436147) Vibrio cholerae M66-2 7773528 YP_002811019.1 CDS VCM66_2267 NC_012578.1 2436275 2438614 D hypothetical protein 2436275..2438614 Vibrio cholerae M66-2 7773529 YP_002811020.1 CDS serB NC_012578.1 2438819 2439805 R catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase complement(2438819..2439805) Vibrio cholerae M66-2 7773530 YP_002811021.1 CDS VCM66_2269 NC_012578.1 2439902 2440525 D putative smp protein 2439902..2440525 Vibrio cholerae M66-2 7773531 YP_002811022.1 CDS deoD NC_012578.1 2440607 2441332 R catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase complement(2440607..2441332) Vibrio cholerae M66-2 7773532 YP_002811023.1 CDS deoB NC_012578.1 2441415 2442635 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(2441415..2442635) Vibrio cholerae M66-2 7773533 YP_002811024.1 CDS deoA NC_012578.1 2442653 2444080 R Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase complement(2442653..2444080) Vibrio cholerae M66-2 7773534 YP_002811025.1 CDS deoC NC_012578.1 2444087 2444866 R catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase complement(2444087..2444866) Vibrio cholerae M66-2 7773535 YP_002811026.1 CDS VCM66_2274 NC_012578.1 2444968 2445156 D hypothetical protein 2444968..2445156 Vibrio cholerae M66-2 7773536 YP_002811027.1 CDS VCM66_2275 NC_012578.1 2445468 2446724 R NupC family protein complement(2445468..2446724) Vibrio cholerae M66-2 7773537 YP_002811028.1 CDS VCM66_2276 NC_012578.1 2446911 2447762 R Putative deoxyribonuclease yjjV complement(2446911..2447762) Vibrio cholerae M66-2 7773538 YP_002811029.1 CDS VCM66_2277 NC_012578.1 2447707 2447850 R hypothetical protein complement(2447707..2447850) Vibrio cholerae M66-2 7773539 YP_002811030.1 CDS VCM66_2278 NC_012578.1 2447877 2448650 R hypothetical protein complement(2447877..2448650) Vibrio cholerae M66-2 7773540 YP_002811031.1 CDS VCM66_2279 NC_012578.1 2448814 2450244 R sodium/alanine symporter complement(2448814..2450244) Vibrio cholerae M66-2 7773541 YP_002811032.1 CDS VCM66_2280 NC_012578.1 2450883 2451116 D hypothetical protein 2450883..2451116 Vibrio cholerae M66-2 7773542 YP_002811033.1 CDS VCM66_2281 NC_012578.1 2451260 2451901 R hypothetical protein complement(2451260..2451901) Vibrio cholerae M66-2 7773543 YP_002811034.1 CDS ung NC_012578.1 2451901 2452581 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(2451901..2452581) Vibrio cholerae M66-2 7773544 YP_002811035.1 CDS nfo NC_012578.1 2452950 2453810 R Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV complement(2452950..2453810) Vibrio cholerae M66-2 7773545 YP_002811036.1 CDS VCM66_2284 NC_012578.1 2454156 2454533 D stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 2454156..2454533 Vibrio cholerae M66-2 7773546 YP_002811037.1 CDS thrC NC_012578.1 2454613 2455893 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(2454613..2455893) Vibrio cholerae M66-2 7773547 YP_002811038.1 CDS thrB NC_012578.1 2455890 2456846 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(2455890..2456846) Vibrio cholerae M66-2 7773548 YP_002811039.1 CDS thrA NC_012578.1 2456867 2459344 R multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I complement(2456867..2459344) Vibrio cholerae M66-2 7773549 YP_002811040.1 CDS VCM66_2288 NC_012578.1 2459874 2460356 D hypothetical protein 2459874..2460356 Vibrio cholerae M66-2 7773550 YP_002811041.1 CDS menG-1 NC_012578.1 2460353 2460841 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(2460353..2460841) Vibrio cholerae M66-2 7773551 YP_002811042.1 CDS VCM66_2290 NC_012578.1 2460868 2461251 R hypothetical protein complement(2460868..2461251) Vibrio cholerae M66-2 7773552 YP_002811043.1 CDS fexA NC_012578.1 2461566 2462282 D two-component response regulator 2461566..2462282 Vibrio cholerae M66-2 7773553 YP_002811044.1 CDS fexB NC_012578.1 2462341 2464698 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(2462341..2464698) Vibrio cholerae M66-2 7773554 YP_002811045.1 CDS VCM66_2293 NC_012578.1 2464805 2466544 R PAS/GGDEF family protein complement(2464805..2466544) Vibrio cholerae M66-2 7773555 YP_002811046.1 CDS VCM66_2294 NC_012578.1 2466612 2467562 R hypothetical protein complement(2466612..2467562) Vibrio cholerae M66-2 7773556 YP_002811047.1 CDS VCM66_2295 NC_012578.1 2467584 2467703 R hypothetical protein complement(2467584..2467703) Vibrio cholerae M66-2 7773557 YP_002811048.1 CDS gltB-1 NC_012578.1 2468081 2472673 D glutamate synthase, large subunit 2468081..2472673 Vibrio cholerae M66-2 7773558 YP_002811049.1 CDS gltD NC_012578.1 2472674 2474143 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 2472674..2474143 Vibrio cholerae M66-2 7773559 YP_002811050.1 CDS VCM66_2298 NC_012578.1 2474177 2474287 D hypothetical protein 2474177..2474287 Vibrio cholerae M66-2 7773560 YP_002811051.1 CDS gltB NC_012578.1 2474671 2479134 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 2474671..2479134 Vibrio cholerae M66-2 7773561 YP_002811052.1 CDS gltD NC_012578.1 2479150 2480565 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 2479150..2480565 Vibrio cholerae M66-2 7773562 YP_002811053.1 CDS VCM66_2301 NC_012578.1 2480752 2481186 D hypothetical protein 2480752..2481186 Vibrio cholerae M66-2 7773563 YP_002811054.1 CDS pfs NC_012578.1 2481274 2481969 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2481274..2481969 Vibrio cholerae M66-2 7773564 YP_002811055.1 CDS VCM66_2303 NC_012578.1 2481982 2482935 D catalyzes the formation of adenosylcobinamide-phosphate from adenosylcobyric acid; adenosylcobinamide-phosphate synthase 2481982..2482935 Vibrio cholerae M66-2 7773565 YP_002811056.1 CDS VCM66_2304 NC_012578.1 2482936 2483766 D Vitamin B12-binding protein 2482936..2483766 Vibrio cholerae M66-2 7773566 YP_002811057.1 CDS VCM66_2305 NC_012578.1 2483750 2484469 D hypothetical protein 2483750..2484469 Vibrio cholerae M66-2 7773567 YP_002811058.1 CDS VCM66_2306 NC_012578.1 2484621 2485481 D LysR family transcriptional regulator 2484621..2485481 Vibrio cholerae M66-2 7773568 YP_002811059.1 CDS VCM66_2307 NC_012578.1 2485411 2486196 R putative Inner membrane protein complement(2485411..2486196) Vibrio cholerae M66-2 7773569 YP_002811060.1 CDS VCM66_2308 NC_012578.1 2486658 2487629 D RNA-directed DNA polymerase 2486658..2487629 Vibrio cholerae M66-2 7773570 YP_002811061.1 CDS VCM66_2310 NC_012578.1 2489264 2489881 D hypothetical protein 2489264..2489881 Vibrio cholerae M66-2 7773966 YP_002811062.1 CDS VCM66_2311 NC_012578.1 2490492 2490974 D hypothetical protein 2490492..2490974 Vibrio cholerae M66-2 7773572 YP_002811063.1 CDS carB NC_012578.1 2491064 2494294 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(2491064..2494294) Vibrio cholerae M66-2 7773573 YP_002811064.1 CDS carA NC_012578.1 2494311 2495450 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(2494311..2495450) Vibrio cholerae M66-2 7773574 YP_002811065.1 CDS dapB NC_012578.1 2495933 2496742 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(2495933..2496742) Vibrio cholerae M66-2 7773575 YP_002811066.1 CDS mutT NC_012578.1 2496857 2497255 R mutator MutT protein complement(2496857..2497255) Vibrio cholerae M66-2 7773576 YP_002811067.1 CDS VCM66_2316 NC_012578.1 2497241 2497408 D hypothetical protein 2497241..2497408 Vibrio cholerae M66-2 7773577 YP_002811068.1 CDS secA NC_012578.1 2497405 2500116 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(2497405..2500116) Vibrio cholerae M66-2 7773578 YP_002811069.1 CDS VCM66_2318 NC_012578.1 2500470 2500943 D hypothetical protein 2500470..2500943 Vibrio cholerae M66-2 7773579 YP_002811070.1 CDS lpxC NC_012578.1 2501048 2501965 R zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(2501048..2501965) Vibrio cholerae M66-2 7773580 YP_002811071.1 CDS ftsz NC_012578.1 2502063 2503259 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(2502063..2503259) Vibrio cholerae M66-2 7773581 YP_002811072.1 CDS ftsA NC_012578.1 2503290 2504552 R ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA complement(2503290..2504552) Vibrio cholerae M66-2 7773582 YP_002811073.1 CDS ftsQ NC_012578.1 2504545 2505327 R cell division protein FtsQ complement(2504545..2505327) Vibrio cholerae M66-2 7773583 YP_002811074.1 CDS murC NC_012578.1 2505509 2507029 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(2505509..2507029) Vibrio cholerae M66-2 7773584 YP_002811075.1 CDS murG NC_012578.1 2506983 2508047 R UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP diphospho-muramoyl pentapeptide beta-N acetylglucosaminyl transferase complement(2506983..2508047) Vibrio cholerae M66-2 7773585 YP_002811076.1 CDS ftsW NC_012578.1 2508031 2509227 R cell division protein FtsW complement(2508031..2509227) Vibrio cholerae M66-2 7773586 YP_002811077.1 CDS murD NC_012578.1 2509244 2510647 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(2509244..2510647) Vibrio cholerae M66-2 7773587 YP_002811078.1 CDS mraY NC_012578.1 2510590 2511672 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(2510590..2511672) Vibrio cholerae M66-2 7773588 YP_002811079.1 CDS murF NC_012578.1 2511669 2513030 R UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase complement(2511669..2513030) Vibrio cholerae M66-2 7773589 YP_002811080.1 CDS murE NC_012578.1 2513027 2514565 R involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase complement(2513027..2514565) Vibrio cholerae M66-2 7773590 YP_002811081.1 CDS ftsI NC_012578.1 2514531 2516273 R penicillin-binding protein 3 complement(2514531..2516273) Vibrio cholerae M66-2 7773591 YP_002811082.1 CDS ftsL NC_012578.1 2516270 2516590 R cell division protein FtsL complement(2516270..2516590) Vibrio cholerae M66-2 7773592 YP_002811083.1 CDS mraW NC_012578.1 2516600 2517550 R S-adenosyl-methyltransferase MraW complement(2516600..2517550) Vibrio cholerae M66-2 7773593 YP_002811084.1 CDS lpdA NC_012578.1 2518322 2519749 R E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(2518322..2519749) Vibrio cholerae M66-2 7773594 YP_002811085.1 CDS aceF NC_012578.1 2520017 2521930 R E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase complement(2520017..2521930) Vibrio cholerae M66-2 7773595 YP_002811086.1 CDS aceE NC_012578.1 2521931 2524591 R E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 complement(2521931..2524591) Vibrio cholerae M66-2 7773596 YP_002811087.1 CDS pdhR NC_012578.1 2524641 2525411 R activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR complement(2524641..2525411) Vibrio cholerae M66-2 7773597 YP_002811088.1 CDS VCM66_2339 NC_012578.1 2525895 2527799 D putative 2,3-cyclic-nucleotide 2-phosphodiesterase 2525895..2527799 Vibrio cholerae M66-2 7773598 YP_002811089.1 CDS recJ NC_012578.1 2527844 2529598 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(2527844..2529598) Vibrio cholerae M66-2 7773599 YP_002811090.1 CDS dsbC NC_012578.1 2529642 2530394 R thiol:disulfide interchange protein DsbC complement(2529642..2530394) Vibrio cholerae M66-2 7773600 YP_002811091.1 CDS xerD NC_012578.1 2530411 2531319 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(2530411..2531319) Vibrio cholerae M66-2 7773601 YP_002811092.1 CDS fldB NC_012578.1 2531379 2531975 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 2531379..2531975 Vibrio cholerae M66-2 7773602 YP_002811093.1 CDS ampD NC_012578.1 2532253 2532798 R N-acetyl-anhydromuranmyl-L-alanine amidase complement(2532253..2532798) Vibrio cholerae M66-2 7773603 YP_002811094.1 CDS nadC NC_012578.1 2533094 2533984 D catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 2533094..2533984 Vibrio cholerae M66-2 7773604 YP_002811095.1 CDS pilA NC_012578.1 2534187 2534690 D fimbrial protein 2534187..2534690 Vibrio cholerae M66-2 7773605 YP_002811096.1 CDS pilB NC_012578.1 2534690 2536378 D type IV pilus assembly protein PilB 2534690..2536378 Vibrio cholerae M66-2 7773606 YP_002811097.1 CDS pilC NC_012578.1 2536421 2537647 D type IV pilin biogenesis protein PilC 2536421..2537647 Vibrio cholerae M66-2 7773607 YP_002811098.1 CDS pilD NC_012578.1 2537705 2538580 D leader peptidase PilD 2537705..2538580 Vibrio cholerae M66-2 7773608 YP_002811099.1 CDS coaE NC_012578.1 2538544 2539185 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 2538544..2539185 Vibrio cholerae M66-2 7773609 YP_002811100.1 CDS VCM66_2351 NC_012578.1 2539217 2539957 D hypothetical protein 2539217..2539957 Vibrio cholerae M66-2 7773610 YP_002811101.1 CDS VCM66_2352 NC_012578.1 2540099 2540296 D zinc-binding protein 2540099..2540296 Vibrio cholerae M66-2 7773611 YP_002811102.1 CDS parC NC_012578.1 2540345 2542630 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(2540345..2542630) Vibrio cholerae M66-2 7773612 YP_002811103.1 CDS parE NC_012578.1 2542634 2544514 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(2542634..2544514) Vibrio cholerae M66-2 7773613 YP_002811104.1 CDS VCM66_2355 NC_012578.1 2544843 2545430 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA complement(2544843..2545430) Vibrio cholerae M66-2 7773614 YP_002811105.1 CDS cpdA NC_012578.1 2545432 2546250 R cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(2545432..2546250) Vibrio cholerae M66-2 7773615 YP_002811106.1 CDS VCM66_2357 NC_012578.1 2546275 2546721 R hypothetical protein complement(2546275..2546721) Vibrio cholerae M66-2 7773616 YP_002811107.1 CDS VCM66_2358 NC_012578.1 2546728 2547354 R MutT/nudix family protein complement(2546728..2547354) Vibrio cholerae M66-2 7773617 YP_002811108.1 CDS tolC NC_012578.1 2547586 2548902 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 2547586..2548902 Vibrio cholerae M66-2 7773618 YP_002811109.1 CDS VCM66_2360 NC_012578.1 2549008 2550438 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(2549008..2550438) Vibrio cholerae M66-2 7773619 YP_002811110.1 CDS glnE NC_012578.1 2550502 2553348 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(2550502..2553348) Vibrio cholerae M66-2 7773620 YP_002811111.1 CDS VCM66_2362 NC_012578.1 2553472 2554773 R methyl-accepting chemotaxis protein complement(2553472..2554773) Vibrio cholerae M66-2 7773621 YP_002811112.1 CDS VCM66_2363 NC_012578.1 2555213 2556730 R hypothetical protein complement(2555213..2556730) Vibrio cholerae M66-2 7773622 YP_002811113.1 CDS VCM66_2364 NC_012578.1 2556930 2557616 D hypothetical protein 2556930..2557616 Vibrio cholerae M66-2 7773623 YP_002811114.1 CDS VCM66_2365 NC_012578.1 2557720 2559021 D pho4 family protein 2557720..2559021 Vibrio cholerae M66-2 7773624 YP_002811115.1 CDS VCM66_2366 NC_012578.1 2559188 2559796 D hypothetical protein 2559188..2559796 Vibrio cholerae M66-2 7773625 YP_002811116.1 CDS VCM66_2367 NC_012578.1 2559888 2560658 R putative general secretion pathway protein B complement(2559888..2560658) Vibrio cholerae M66-2 7773626 YP_002811117.1 CDS exeA NC_012578.1 2560658 2562247 R general secretion pathway protein A complement(2560658..2562247) Vibrio cholerae M66-2 7773627 YP_002811118.1 CDS cca NC_012578.1 2562340 2563551 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 2562340..2563551 Vibrio cholerae M66-2 7773628 YP_002811119.1 CDS eno NC_012578.1 2563653 2564954 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(2563653..2564954) Vibrio cholerae M66-2 7773629 YP_002811120.1 CDS pyrG NC_012578.1 2565033 2566670 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(2565033..2566670) Vibrio cholerae M66-2 7773630 YP_002811121.1 CDS VCM66_2372 NC_012578.1 2566756 2566896 D hypothetical protein 2566756..2566896 Vibrio cholerae M66-2 7773631 YP_002811122.1 CDS mazG NC_012578.1 2566945 2567781 R functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase complement(2566945..2567781) Vibrio cholerae M66-2 7773632 YP_002811123.1 CDS relA NC_012578.1 2567860 2570076 R GTP pyrophosphokinase complement(2567860..2570076) Vibrio cholerae M66-2 7773633 YP_002811124.1 CDS rumA NC_012578.1 2570140 2571462 R in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase complement(2570140..2571462) Vibrio cholerae M66-2 7773634 YP_002811125.1 CDS VCM66_2376 NC_012578.1 2571634 2574417 D part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 2571634..2574417 Vibrio cholerae M66-2 7773635 YP_002811126.1 CDS vpvC NC_012578.1 2574405 2575697 R GGDEF family protein complement(2574405..2575697) Vibrio cholerae M66-2 7773636 YP_002811127.1 CDS VCM66_2378 NC_012578.1 2575690 2576100 R hypothetical protein complement(2575690..2576100) Vibrio cholerae M66-2 7773637 YP_002811128.1 CDS VCM66_2379 NC_012578.1 2576110 2577447 R hypothetical protein complement(2576110..2577447) Vibrio cholerae M66-2 7773638 YP_002811129.1 CDS acpS NC_012578.1 2577650 2578030 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(2577650..2578030) Vibrio cholerae M66-2 7773639 YP_002811130.1 CDS pdxJ NC_012578.1 2578034 2578765 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(2578034..2578765) Vibrio cholerae M66-2 7773640 YP_002811131.1 CDS recO NC_012578.1 2578762 2579487 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(2578762..2579487) Vibrio cholerae M66-2 7773641 YP_002811132.1 CDS era NC_012578.1 2579557 2580534 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(2579557..2580534) Vibrio cholerae M66-2 7773642 YP_002811133.1 CDS rnc NC_012578.1 2580527 2581204 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(2580527..2581204) Vibrio cholerae M66-2 7773643 YP_002811134.1 CDS lepB NC_012578.1 2581236 2582132 R signal peptidase I complement(2581236..2582132) Vibrio cholerae M66-2 7773644 YP_002811135.1 CDS lepA NC_012578.1 2582224 2584017 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(2582224..2584017) Vibrio cholerae M66-2 7773645 YP_002811136.1 CDS rseC NC_012578.1 2584130 2584600 R sigma-E factor regulatory protein RseC complement(2584130..2584600) Vibrio cholerae M66-2 7773646 YP_002811137.1 CDS rseB NC_012578.1 2584597 2585562 R periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE complement(2584597..2585562) Vibrio cholerae M66-2 7773647 YP_002811138.1 CDS rseA NC_012578.1 2585559 2586197 R sigma-E factor negative regulatory protein RseA complement(2585559..2586197) Vibrio cholerae M66-2 7773648 YP_002811139.1 CDS rpoE NC_012578.1 2586211 2586783 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE complement(2586211..2586783) Vibrio cholerae M66-2 7773649 YP_002811140.1 CDS VCM66_2391 NC_012578.1 2587114 2587311 R hypothetical protein complement(2587114..2587311) Vibrio cholerae M66-2 7773650 YP_002811141.1 CDS nadB NC_012578.1 2587243 2588895 D catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2587243..2588895 Vibrio cholerae M66-2 7773651 YP_002811142.1 CDS VCM66_2393 NC_012578.1 2588920 2589366 R hypothetical protein complement(2588920..2589366) Vibrio cholerae M66-2 7773652 YP_002811143.1 CDS VCM66_2394 NC_012578.1 2589314 2589574 R hypothetical protein complement(2589314..2589574) Vibrio cholerae M66-2 7773653 YP_002811144.1 CDS VCM66_2395 NC_012578.1 2589727 2590698 D hypothetical protein 2589727..2590698 Vibrio cholerae M66-2 7773654 YP_002811145.1 CDS VCM66_2396 NC_012578.1 2591305 2591538 D hypothetical protein 2591305..2591538 Vibrio cholerae M66-2 7773655 YP_002811146.1 CDS visC NC_012578.1 2591639 2592868 R catalyzes the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone from 2-octaprenyl-6-methoxyphenol; 2-octaprenyl-6-methoxyphenol hydroxylase complement(2591639..2592868) Vibrio cholerae M66-2 7773656 YP_002811147.1 CDS ubiH NC_012578.1 2592880 2594088 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(2592880..2594088) Vibrio cholerae M66-2 7773657 YP_002811148.1 CDS VCM66_2399 NC_012578.1 2594109 2594684 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(2594109..2594684) Vibrio cholerae M66-2 7773658 YP_002811149.1 CDS VCM66_2400 NC_012578.1 2594926 2595234 D hypothetical protein 2594926..2595234 Vibrio cholerae M66-2 7773659 YP_002811150.1 CDS VCM66_2401 NC_012578.1 2595434 2596018 D hypothetical protein 2595434..2596018 Vibrio cholerae M66-2 7773660 YP_002811151.1 CDS rpiA NC_012578.1 2596128 2596784 D Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 2596128..2596784 Vibrio cholerae M66-2 7773661 YP_002811152.1 CDS serA NC_012578.1 2597038 2598267 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 2597038..2598267 Vibrio cholerae M66-2 7773662 YP_002811153.1 CDS ilvH NC_012578.1 2598499 2598993 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(2598499..2598993) Vibrio cholerae M66-2 7773663 YP_002811154.1 CDS ilvI NC_012578.1 2598995 2600716 R acetolactate synthase 3 catalytic subunit complement(2598995..2600716) Vibrio cholerae M66-2 7773664 YP_002811155.1 CDS VCM66_2406 NC_012578.1 2601201 2603006 R putative long-chain-fatty-acid--CoA ligase complement(2601201..2603006) Vibrio cholerae M66-2 7773665 YP_002811156.1 CDS leuO NC_012578.1 2603183 2604148 R activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator complement(2603183..2604148) Vibrio cholerae M66-2 7773666 YP_002811157.1 CDS VCM66_2408 NC_012578.1 2604166 2604267 R hypothetical protein complement(2604166..2604267) Vibrio cholerae M66-2 7773667 YP_002811158.1 CDS VCM66_2409 NC_012578.1 2604448 2605536 R hypothetical protein complement(2604448..2605536) Vibrio cholerae M66-2 7773668 YP_002811159.1 CDS VCM66_2410 NC_012578.1 2605533 2606069 R hypothetical protein complement(2605533..2606069) Vibrio cholerae M66-2 7773669 YP_002811160.1 CDS VCM66_2411 NC_012578.1 2606196 2606831 R TetR family transcriptional regulator complement(2606196..2606831) Vibrio cholerae M66-2 7773670 YP_002811161.1 CDS leuA NC_012578.1 2607214 2608764 D catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 2607214..2608764 Vibrio cholerae M66-2 7773671 YP_002811162.1 CDS leuB NC_012578.1 2608876 2609967 D catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 2608876..2609967 Vibrio cholerae M66-2 7773672 YP_002811163.1 CDS leuC NC_012578.1 2610025 2611428 D dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 2610025..2611428 Vibrio cholerae M66-2 7773673 YP_002811164.1 CDS leuD NC_012578.1 2611444 2612046 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 2611444..2612046 Vibrio cholerae M66-2 7773674 YP_002811165.1 CDS VCM66_2416 NC_012578.1 2612147 2612938 D hypothetical protein 2612147..2612938 Vibrio cholerae M66-2 7773675 YP_002811166.1 CDS VCM66_2418 NC_012578.1 2618623 2618715 R hypothetical protein complement(2618623..2618715) Vibrio cholerae M66-2 7773973 YP_002811167.1 CDS VCM66_2419 NC_012578.1 2618958 2620211 R rpfG-type response regulator complement(2618958..2620211) Vibrio cholerae M66-2 7773677 YP_002811168.1 CDS VCM66_2420 NC_012578.1 2620642 2621124 D hypothetical protein 2620642..2621124 Vibrio cholerae M66-2 7774043 YP_002811169.1 CDS VCM66_2421 NC_012578.1 2621230 2622300 R putative Inner membrane protein complement(2621230..2622300) Vibrio cholerae M66-2 7773679 YP_002811170.1 CDS VCM66_2422 NC_012578.1 2622304 2623404 R hypothetical protein complement(2622304..2623404) Vibrio cholerae M66-2 7773680 YP_002811171.1 CDS pepA NC_012578.1 2623598 2625109 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 2623598..2625109 Vibrio cholerae M66-2 7773681 YP_002811172.1 CDS holC NC_012578.1 2625193 2625642 D binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 2625193..2625642 Vibrio cholerae M66-2 7773682 YP_002811173.1 CDS valS NC_012578.1 2625736 2628597 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 2625736..2628597 Vibrio cholerae M66-2 7773683 YP_002811174.1 CDS VCM66_2426 NC_012578.1 2628675 2629652 R 2-hydroxyacid dehydrogenase family protein complement(2628675..2629652) Vibrio cholerae M66-2 7773684 YP_002811175.1 CDS rluA-1 NC_012578.1 2629692 2630429 R ribosomal large subunit pseudouridine synthase A complement(2629692..2630429) Vibrio cholerae M66-2 7773685 YP_002811176.1 CDS hepA NC_012578.1 2630526 2633435 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(2630526..2633435) Vibrio cholerae M66-2 7773686 YP_002811177.1 CDS VCM66_2429 NC_012578.1 2633857 2635233 D PhoH-like protein 2633857..2635233 Vibrio cholerae M66-2 7773687 YP_002811178.1 CDS argF NC_012578.1 2635383 2636387 D catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2635383..2636387 Vibrio cholerae M66-2 7773688 YP_002811179.1 CDS VCM66_2431 NC_012578.1 2636485 2636580 D hypothetical protein 2636485..2636580 Vibrio cholerae M66-2 7773689 YP_002811180.1 CDS pyrB NC_012578.1 2636574 2637566 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 2636574..2637566 Vibrio cholerae M66-2 7773690 YP_002811181.1 CDS pyrI NC_012578.1 2637578 2638045 D involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 2637578..2638045 Vibrio cholerae M66-2 7773691 YP_002811182.1 CDS VCM66_2434 NC_012578.1 2638150 2638539 D hypothetical protein 2638150..2638539 Vibrio cholerae M66-2 7773692 YP_002811183.1 CDS plsC NC_012578.1 2638620 2639405 R 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(2638620..2639405) Vibrio cholerae M66-2 7773693 YP_002811184.1 CDS murA NC_012578.1 2639427 2640686 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(2639427..2640686) Vibrio cholerae M66-2 7773694 YP_002811185.1 CDS VCM66_2437 NC_012578.1 2640694 2640948 R BolA/YrbA family protein complement(2640694..2640948) Vibrio cholerae M66-2 7773695 YP_002811186.1 CDS VCM66_2438 NC_012578.1 2640941 2641270 R putative anti-sigma B factor antagonist complement(2640941..2641270) Vibrio cholerae M66-2 7773696 YP_002811187.1 CDS VCM66_2439 NC_012578.1 2641267 2641908 R hypothetical protein complement(2641267..2641908) Vibrio cholerae M66-2 7773697 YP_002811188.1 CDS VCM66_2440 NC_012578.1 2641909 2642400 R hypothetical protein complement(2641909..2642400) Vibrio cholerae M66-2 7773698 YP_002811189.1 CDS VCM66_2441 NC_012578.1 2642403 2643179 R hypothetical protein complement(2642403..2643179) Vibrio cholerae M66-2 7773699 YP_002811190.1 CDS VCM66_2442 NC_012578.1 2643184 2643987 R ABC transporter ATP-binding protein complement(2643184..2643987) Vibrio cholerae M66-2 7773700 YP_002811191.1 CDS VCM66_2443 NC_012578.1 2644115 2644306 R hypothetical protein complement(2644115..2644306) Vibrio cholerae M66-2 7773701 YP_002811192.1 CDS VCM66_2444 NC_012578.1 2644544 2645542 D putative Inner membrane protein 2644544..2645542 Vibrio cholerae M66-2 7773702 YP_002811193.1 CDS VCM66_2445 NC_012578.1 2645592 2646572 D Arabinose 5-phosphate isomerase 2645592..2646572 Vibrio cholerae M66-2 7773703 YP_002811194.1 CDS VCM66_2446 NC_012578.1 2646572 2647129 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 2646572..2647129 Vibrio cholerae M66-2 7773704 YP_002811195.1 CDS VCM66_2447 NC_012578.1 2647126 2647689 D hypothetical protein 2647126..2647689 Vibrio cholerae M66-2 7773705 YP_002811196.1 CDS VCM66_2448 NC_012578.1 2647625 2648164 D hypothetical protein 2647625..2648164 Vibrio cholerae M66-2 7773706 YP_002811197.1 CDS VCM66_2449 NC_012578.1 2648167 2648892 D ABC transporter ATP-binding protein 2648167..2648892 Vibrio cholerae M66-2 7773707 YP_002811198.1 CDS rpoN NC_012578.1 2648948 2650411 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 2648948..2650411 Vibrio cholerae M66-2 7773708 YP_002811199.1 CDS VCM66_2451 NC_012578.1 2650436 2650723 D putative sigma-54 modulation protein 2650436..2650723 Vibrio cholerae M66-2 7773709 YP_002811200.1 CDS ptsN NC_012578.1 2650726 2651172 D PTS system, nitrogen regulatory IIA component 2650726..2651172 Vibrio cholerae M66-2 7773710 YP_002811201.1 CDS VCM66_2453 NC_012578.1 2651185 2652045 D hypothetical protein 2651185..2652045 Vibrio cholerae M66-2 7773711 YP_002811202.1 CDS ptsO NC_012578.1 2652054 2652332 D phosphocarrier protein NPr 2652054..2652332 Vibrio cholerae M66-2 7773712 YP_002811203.1 CDS mgtE-2 NC_012578.1 2652493 2653854 D magnesium transporter 2652493..2653854 Vibrio cholerae M66-2 7773713 YP_002811204.1 CDS pmbA NC_012578.1 2653926 2655269 R protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA complement(2653926..2655269) Vibrio cholerae M66-2 7773714 YP_002811205.1 CDS VCM66_2457 NC_012578.1 2655368 2655949 D hypothetical protein 2655368..2655949 Vibrio cholerae M66-2 7773715 YP_002811206.1 CDS VCM66_2458 NC_012578.1 2656052 2656786 R putative thiamine ABC transporter ATP-binding protein complement(2656052..2656786) Vibrio cholerae M66-2 7773716 YP_002811207.1 CDS thiP NC_012578.1 2656780 2658372 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(2656780..2658372) Vibrio cholerae M66-2 7773717 YP_002811208.1 CDS tbpA NC_012578.1 2658382 2659374 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(2658382..2659374) Vibrio cholerae M66-2 7773718 YP_002811209.1 CDS VCM66_2461 NC_012578.1 2659244 2659636 R hypothetical protein complement(2659244..2659636) Vibrio cholerae M66-2 7773719 YP_002811210.1 CDS ubiX NC_012578.1 2659636 2660271 R aromatic acid decarboxylase complement(2659636..2660271) Vibrio cholerae M66-2 7773720 YP_002811211.1 CDS mpl NC_012578.1 2660278 2661633 R UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase complement(2660278..2661633) Vibrio cholerae M66-2 7773721 YP_002811212.1 CDS VCM66_2464 NC_012578.1 2661622 2661885 D hypothetical protein 2661622..2661885 Vibrio cholerae M66-2 7773722 YP_002811213.1 CDS fbp NC_012578.1 2661939 2662949 D catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 2661939..2662949 Vibrio cholerae M66-2 7773723 YP_002811214.1 CDS ppa NC_012578.1 2663119 2663649 D catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 2663119..2663649 Vibrio cholerae M66-2 7773724 YP_002811215.1 CDS VCM66_2467 NC_012578.1 2663709 2664056 R hypothetical protein complement(2663709..2664056) Vibrio cholerae M66-2 7773725 YP_002811216.1 CDS VCM66_2468 NC_012578.1 2664067 2667831 R hypothetical protein complement(2664067..2667831) Vibrio cholerae M66-2 7773726 YP_002811217.1 CDS VCM66_2469 NC_012578.1 2667828 2669576 R hypothetical protein complement(2667828..2669576) Vibrio cholerae M66-2 7773727 YP_002811218.1 CDS msrA NC_012578.1 2669722 2670360 D this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 2669722..2670360 Vibrio cholerae M66-2 7773728 YP_002811219.1 CDS VCM66_2471 NC_012578.1 2670442 2670993 D hypothetical protein 2670442..2670993 Vibrio cholerae M66-2 7773729 YP_002811220.1 CDS VCM66_2472 NC_012578.1 2671211 2671516 D hypothetical protein 2671211..2671516 Vibrio cholerae M66-2 7773730 YP_002811221.1 CDS VCM66_2473 NC_012578.1 2671565 2672293 D hypothetical protein 2671565..2672293 Vibrio cholerae M66-2 7773731 YP_002811222.1 CDS VCM66_2474 NC_012578.1 2672375 2673091 D ABC transporter ATP-binding protein 2672375..2673091 Vibrio cholerae M66-2 7773732 YP_002811223.1 CDS VCM66_2475 NC_012578.1 2673082 2674347 D hypothetical protein 2673082..2674347 Vibrio cholerae M66-2 7773733 YP_002811224.1 CDS VCM66_2476 NC_012578.1 2674400 2674921 D hypothetical protein 2674400..2674921 Vibrio cholerae M66-2 7773734 YP_002811225.1 CDS VCM66_2477 NC_012578.1 2675232 2676131 D hypothetical protein 2675232..2676131 Vibrio cholerae M66-2 7773735 YP_002811226.1 CDS cysC NC_012578.1 2676204 2676851 R converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase complement(2676204..2676851) Vibrio cholerae M66-2 7773736 YP_002811227.1 CDS cysN NC_012578.1 2676862 2678292 R may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 complement(2676862..2678292) Vibrio cholerae M66-2 7773737 YP_002811228.1 CDS cysD NC_012578.1 2678310 2679218 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(2678310..2679218) Vibrio cholerae M66-2 7773738 YP_002811229.1 CDS cysG NC_012578.1 2679321 2680220 R catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; uroporphyrin-III C-methyltransferase complement(2679321..2680220) Vibrio cholerae M66-2 7773739 YP_002811230.1 CDS cpdB NC_012578.1 2680421 2682466 D periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 2680421..2682466 Vibrio cholerae M66-2 7773740 YP_002811231.1 CDS VCM66_2483 NC_012578.1 2682586 2683155 D hypothetical protein 2682586..2683155 Vibrio cholerae M66-2 7773741 YP_002811232.1 CDS dbpA NC_012578.1 2683158 2684540 R exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA complement(2683158..2684540) Vibrio cholerae M66-2 7773742 YP_002811233.1 CDS elaA NC_012578.1 2684766 2685215 D elaA protein 2684766..2685215 Vibrio cholerae M66-2 7773743 YP_002811234.1 CDS VCM66_2486 NC_012578.1 2685218 2686111 D hypothetical protein 2685218..2686111 Vibrio cholerae M66-2 7773744 YP_002811235.1 CDS VCM66_2487 NC_012578.1 2686061 2686633 R hypothetical protein complement(2686061..2686633) Vibrio cholerae M66-2 7773745 YP_002811236.1 CDS fklB NC_012578.1 2686844 2687473 D FKBP-type peptidyl-prolyl cis-trans isomerase 2686844..2687473 Vibrio cholerae M66-2 7773746 YP_002811237.1 CDS VCM66_2489 NC_012578.1 2687609 2688091 D hypothetical protein 2687609..2688091 Vibrio cholerae M66-2 7773747 YP_002811238.1 CDS rplQ NC_012578.1 2688235 2688621 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(2688235..2688621) Vibrio cholerae M66-2 7773748 YP_002811239.1 CDS rpoA NC_012578.1 2688648 2689640 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(2688648..2689640) Vibrio cholerae M66-2 7773749 YP_002811240.1 CDS rpsD NC_012578.1 2689665 2690285 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(2689665..2690285) Vibrio cholerae M66-2 7773750 YP_002811241.1 CDS rpsK NC_012578.1 2690313 2690702 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(2690313..2690702) Vibrio cholerae M66-2 7773751 YP_002811242.1 CDS rpsM NC_012578.1 2690722 2691078 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(2690722..2691078) Vibrio cholerae M66-2 7773752 YP_002811243.1 CDS rpmJ NC_012578.1 2691228 2691341 R smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 complement(2691228..2691341) Vibrio cholerae M66-2 7773753 YP_002811244.1 CDS secY NC_012578.1 2691380 2692714 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(2691380..2692714) Vibrio cholerae M66-2 7773754 YP_002811245.1 CDS rplO NC_012578.1 2692735 2693169 R late assembly protein; 50S ribosomal protein L15 complement(2692735..2693169) Vibrio cholerae M66-2 7773755 YP_002811246.1 CDS rpmD NC_012578.1 2693175 2693351 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(2693175..2693351) Vibrio cholerae M66-2 7773756 YP_002811247.1 CDS rpsE NC_012578.1 2693358 2693861 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(2693358..2693861) Vibrio cholerae M66-2 7773757 YP_002811248.1 CDS rplR NC_012578.1 2693876 2694229 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(2693876..2694229) Vibrio cholerae M66-2 7773758 YP_002811249.1 CDS rplF NC_012578.1 2694239 2694772 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(2694239..2694772) Vibrio cholerae M66-2 7773759 YP_002811250.1 CDS rpsH NC_012578.1 2694787 2695179 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(2694787..2695179) Vibrio cholerae M66-2 7773760 YP_002811251.1 CDS rpsN NC_012578.1 2695209 2695514 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(2695209..2695514) Vibrio cholerae M66-2 7773761 YP_002811252.1 CDS rplE NC_012578.1 2695532 2696071 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(2695532..2696071) Vibrio cholerae M66-2 7773762 YP_002811253.1 CDS rplX NC_012578.1 2696096 2696413 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(2696096..2696413) Vibrio cholerae M66-2 7773763 YP_002811254.1 CDS rplN NC_012578.1 2696426 2696797 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(2696426..2696797) Vibrio cholerae M66-2 7773764 YP_002811255.1 CDS rpsQ NC_012578.1 2696960 2697214 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(2696960..2697214) Vibrio cholerae M66-2 7773765 YP_002811256.1 CDS rpmC NC_012578.1 2697214 2697405 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(2697214..2697405) Vibrio cholerae M66-2 7773766 YP_002811257.1 CDS rplP NC_012578.1 2697405 2697815 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(2697405..2697815) Vibrio cholerae M66-2 7773767 YP_002811258.1 CDS rpsC NC_012578.1 2697827 2698528 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(2697827..2698528) Vibrio cholerae M66-2 7773768 YP_002811259.1 CDS rplV NC_012578.1 2698548 2698880 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(2698548..2698880) Vibrio cholerae M66-2 7773769 YP_002811260.1 CDS rpsS NC_012578.1 2698891 2699169 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(2698891..2699169) Vibrio cholerae M66-2 7773770 YP_002811261.1 CDS rplB NC_012578.1 2699190 2700014 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(2699190..2700014) Vibrio cholerae M66-2 7773771 YP_002811262.1 CDS rplW NC_012578.1 2700031 2700333 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(2700031..2700333) Vibrio cholerae M66-2 7773772 YP_002811263.1 CDS rplD NC_012578.1 2700330 2700932 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(2700330..2700932) Vibrio cholerae M66-2 7773773 YP_002811264.1 CDS rplC NC_012578.1 2700949 2701578 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(2700949..2701578) Vibrio cholerae M66-2 7773774 YP_002811265.1 CDS rpsJ NC_012578.1 2701593 2701904 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(2701593..2701904) Vibrio cholerae M66-2 7773775 YP_002811266.1 CDS VCM66_2518 NC_012578.1 2702375 2703118 R Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase complement(2702375..2703118) Vibrio cholerae M66-2 7773776 YP_002811267.1 CDS vacB NC_012578.1 2703126 2705591 R ribonuclease R complement(2703126..2705591) Vibrio cholerae M66-2 7773777 YP_002811268.1 CDS VCM66_2520 NC_012578.1 2705735 2707603 D putative Inner membrane protein 2705735..2707603 Vibrio cholerae M66-2 7773778 YP_002811269.1 CDS motX NC_012578.1 2707630 2708265 R sodium-type flagellar protein MotX complement(2707630..2708265) Vibrio cholerae M66-2 7773779 YP_002811270.1 CDS purA NC_012578.1 2708473 2709771 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(2708473..2709771) Vibrio cholerae M66-2 7773780 YP_002811271.1 CDS VCM66_2523 NC_012578.1 2709899 2710879 R putative asparaginase complement(2709899..2710879) Vibrio cholerae M66-2 7773781 YP_002811272.1 CDS slyD NC_012578.1 2711042 2711647 R FKBP-type peptidyl-prolyl cis-trans isomerase complement(2711042..2711647) Vibrio cholerae M66-2 7773782 YP_002811273.1 CDS VCM66_2525 NC_012578.1 2711739 2711939 R hypothetical protein complement(2711739..2711939) Vibrio cholerae M66-2 7773783 YP_002811274.1 CDS kefB NC_012578.1 2711949 2713919 R involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB complement(2711949..2713919) Vibrio cholerae M66-2 7773784 YP_002811275.1 CDS VCM66_2527 NC_012578.1 2713732 2714322 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(2713732..2714322) Vibrio cholerae M66-2 7773785 YP_002811276.1 CDS VCM66_2528 NC_012578.1 2714368 2716362 D ABC transporter ATP-binding protein 2714368..2716362 Vibrio cholerae M66-2 7773786 YP_002811277.1 CDS VCM66_2529 NC_012578.1 2716363 2716848 D hypothetical protein 2716363..2716848 Vibrio cholerae M66-2 7773787 YP_002811278.1 CDS VCM66_2530 NC_012578.1 2716845 2717834 D putative hydrolase 2716845..2717834 Vibrio cholerae M66-2 7773788 YP_002811279.1 CDS VCM66_2532 NC_012578.1 2717962 2718171 D hypothetical protein 2717962..2718171 Vibrio cholerae M66-2 7773789 YP_002811280.1 CDS prkB NC_012578.1 2718268 2719137 D phosphoribulokinase 2718268..2719137 Vibrio cholerae M66-2 7773790 YP_002811281.1 CDS VCM66_2534 NC_012578.1 2719380 2720012 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 2719380..2720012 Vibrio cholerae M66-2 7773791 YP_002811282.1 CDS VCM66_2535 NC_012578.1 2720091 2720882 R hypothetical protein complement(2720091..2720882) Vibrio cholerae M66-2 7773792 YP_002811283.1 CDS astD NC_012578.1 2721025 2722482 R a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase complement(2721025..2722482) Vibrio cholerae M66-2 7773793 YP_002811284.1 CDS VCM66_2537 NC_012578.1 2722492 2723550 R putative arginine/ornithine succinyltransferase complement(2722492..2723550) Vibrio cholerae M66-2 7773794 YP_002811285.1 CDS argD NC_012578.1 2723650 2724861 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein complement(2723650..2724861) Vibrio cholerae M66-2 7773795 YP_002811286.1 CDS pabA NC_012578.1 2725259 2725840 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(2725259..2725840) Vibrio cholerae M66-2 7773796 YP_002811287.1 CDS rimO NC_012578.1 2726094 2727506 D catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 2726094..2727506 Vibrio cholerae M66-2 7773797 YP_002811288.1 CDS VCM66_2541 NC_012578.1 2727583 2730192 R extracellular nuclease-like protein complement(2727583..2730192) Vibrio cholerae M66-2 7773798 YP_002811289.1 CDS VCM66_2542 NC_012578.1 2730462 2731235 R hypothetical protein complement(2730462..2731235) Vibrio cholerae M66-2 7773799 YP_002811290.1 CDS trpS NC_012578.1 2731391 2732488 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(2731391..2732488) Vibrio cholerae M66-2 7773800 YP_002811291.1 CDS gph NC_012578.1 2732535 2733215 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(2732535..2733215) Vibrio cholerae M66-2 7773801 YP_002811292.1 CDS rpe NC_012578.1 2733235 2733945 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(2733235..2733945) Vibrio cholerae M66-2 7773802 YP_002811293.1 CDS dam NC_012578.1 2734036 2734869 R DNA adenine methylase complement(2734036..2734869) Vibrio cholerae M66-2 7773803 YP_002811294.1 CDS VCM66_2547 NC_012578.1 2734939 2736414 R DamX-like protein complement(2734939..2736414) Vibrio cholerae M66-2 7773804 YP_002811295.1 CDS aroB NC_012578.1 2736469 2737569 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(2736469..2737569) Vibrio cholerae M66-2 7773805 YP_002811296.1 CDS aroK NC_012578.1 2737582 2738106 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(2737582..2738106) Vibrio cholerae M66-2 7773806 YP_002811297.1 CDS pilQ NC_012578.1 2738293 2740029 R fimbrial assembly protein complement(2738293..2740029) Vibrio cholerae M66-2 7773807 YP_002811298.1 CDS VCM66_2551 NC_012578.1 2740034 2740552 R putative fimbrial assembly protein PilP complement(2740034..2740552) Vibrio cholerae M66-2 7773808 YP_002811299.1 CDS VCM66_2552 NC_012578.1 2740542 2741141 R putative fimbrial assembly protein PilO complement(2740542..2741141) Vibrio cholerae M66-2 7773809 YP_002811300.1 CDS VCM66_2553 NC_012578.1 2741125 2741715 R putative fimbrial assembly protein PilN complement(2741125..2741715) Vibrio cholerae M66-2 7773810 YP_002811301.1 CDS VCM66_2554 NC_012578.1 2741699 2742715 R putative fimbrial assembly protein PilM complement(2741699..2742715) Vibrio cholerae M66-2 7773811 YP_002811302.1 CDS mrcA NC_012578.1 2742828 2745335 D penicillin-binding protein 1A 2742828..2745335 Vibrio cholerae M66-2 7773812 YP_002811303.1 CDS VCM66_2556 NC_012578.1 2745409 2746302 R Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR complement(2745409..2746302) Vibrio cholerae M66-2 7773813 YP_002811304.1 CDS VCM66_2557 NC_012578.1 2746430 2747173 D peroxiredoxin family protein/glutaredoxin 2746430..2747173 Vibrio cholerae M66-2 7773814 YP_002811305.1 CDS VCM66_2558 NC_012578.1 2747245 2748699 D Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 2747245..2748699 Vibrio cholerae M66-2 7773815 YP_002811306.1 CDS VCM66_2559 NC_012578.1 2748696 2748803 R hypothetical protein complement(2748696..2748803) Vibrio cholerae M66-2 7773816 YP_002811307.1 CDS VCM66_2560 NC_012578.1 2748925 2749188 D hypothetical protein 2748925..2749188 Vibrio cholerae M66-2 7773817 YP_002811308.1 CDS argH NC_012578.1 2749439 2750815 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(2749439..2750815) Vibrio cholerae M66-2 7773818 YP_002811309.1 CDS argG NC_012578.1 2751048 2752262 R catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase complement(2751048..2752262) Vibrio cholerae M66-2 7773819 YP_002811310.1 CDS argB NC_012578.1 2752338 2753126 R catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase complement(2752338..2753126) Vibrio cholerae M66-2 7773820 YP_002811311.1 CDS argC NC_012578.1 2753136 2754176 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase complement(2753136..2754176) Vibrio cholerae M66-2 7773821 YP_002811312.1 CDS argE NC_012578.1 2754293 2755429 D catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 2754293..2755429 Vibrio cholerae M66-2 7773822 YP_002811313.1 CDS ppc NC_012578.1 2755603 2758266 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 2755603..2758266 Vibrio cholerae M66-2 7773823 YP_002811314.1 CDS aphA NC_012578.1 2758625 2759164 D hypothetical protein 2758625..2759164 Vibrio cholerae M66-2 7773824 YP_002811315.1 CDS VCM66_2568 NC_012578.1 2759113 2759241 D hypothetical protein 2759113..2759241 Vibrio cholerae M66-2 7773825 YP_002811316.1 CDS cysE NC_012578.1 2759280 2760101 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(2759280..2760101) Vibrio cholerae M66-2 7773826 YP_002811317.1 CDS VCM66_2570 NC_012578.1 2759988 2760299 D hypothetical protein 2759988..2760299 Vibrio cholerae M66-2 7773827 YP_002811318.1 CDS gpsA NC_012578.1 2760174 2761208 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(2760174..2761208) Vibrio cholerae M66-2 7773828 YP_002811319.1 CDS VCM66_2572 NC_012578.1 2761341 2761511 D hypothetical protein 2761341..2761511 Vibrio cholerae M66-2 7773829 YP_002811320.1 CDS secB NC_012578.1 2761398 2761862 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(2761398..2761862) Vibrio cholerae M66-2 7773830 YP_002811321.1 CDS VCM66_2574 NC_012578.1 2762029 2762463 R hypothetical protein complement(2762029..2762463) Vibrio cholerae M66-2 7773831 YP_002811322.1 CDS yjeA NC_012578.1 2762593 2763642 R lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase complement(2762593..2763642) Vibrio cholerae M66-2 7773832 YP_002811323.1 CDS frdA NC_012578.1 2763876 2765684 D part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 2763876..2765684 Vibrio cholerae M66-2 7773833 YP_002811324.1 CDS frdB NC_012578.1 2765684 2766442 D part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 2765684..2766442 Vibrio cholerae M66-2 7773834 YP_002811325.1 CDS frdC NC_012578.1 2766445 2766828 D part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 2766445..2766828 Vibrio cholerae M66-2 7773835 YP_002811326.1 CDS frdD NC_012578.1 2766809 2767201 D in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 2766809..2767201 Vibrio cholerae M66-2 7773836 YP_002811327.1 CDS efp NC_012578.1 2767315 2767881 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(2767315..2767881) Vibrio cholerae M66-2 7773837 YP_002811328.1 CDS VCM66_2581 NC_012578.1 2767914 2768936 D hypothetical protein 2767914..2768936 Vibrio cholerae M66-2 7773838 YP_002811329.1 CDS VCM66_2582 NC_012578.1 2768973 2769548 R hypothetical protein complement(2768973..2769548) Vibrio cholerae M66-2 7773839 YP_002811330.1 CDS VCM66_2583 NC_012578.1 2769571 2769675 R hypothetical protein complement(2769571..2769675) Vibrio cholerae M66-2 7773840 YP_002811331.1 CDS groEL NC_012578.1 2769744 2771378 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(2769744..2771378) Vibrio cholerae M66-2 7773841 YP_002811332.1 CDS groES NC_012578.1 2771432 2771722 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(2771432..2771722) Vibrio cholerae M66-2 7773842 YP_002811333.1 CDS VCM66_2586 NC_012578.1 2772082 2772699 D hypothetical protein 2772082..2772699 Vibrio cholerae M66-2 7773843 YP_002811334.1 CDS VCM66_2587 NC_012578.1 2772838 2773197 D hypothetical protein 2772838..2773197 Vibrio cholerae M66-2 7773844 YP_002811335.1 CDS VCM66_2588 NC_012578.1 2773324 2773764 R hypothetical protein complement(2773324..2773764) Vibrio cholerae M66-2 7773845 YP_002811336.1 CDS VCM66_2589 NC_012578.1 2773784 2774134 R putative 5-carboxymethyl-2-hydroxymuconate delta isomerase complement(2773784..2774134) Vibrio cholerae M66-2 7773846 YP_002811337.1 CDS tpiA NC_012578.1 2774354 2775151 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 2774354..2775151 Vibrio cholerae M66-2 7773847 YP_002811338.1 CDS VCM66_2591 NC_012578.1 2775269 2776651 D hypothetical protein 2775269..2776651 Vibrio cholerae M66-2 7773848 YP_002811339.1 CDS menG-2 NC_012578.1 2776738 2777253 R regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA complement(2776738..2777253) Vibrio cholerae M66-2 7773849 YP_002811340.1 CDS menA NC_012578.1 2777328 2778245 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(2777328..2778245) Vibrio cholerae M66-2 7773850 YP_002811341.1 CDS hslU NC_012578.1 2778349 2779680 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(2778349..2779680) Vibrio cholerae M66-2 7773851 YP_002811342.1 CDS hslV NC_012578.1 2779746 2780303 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(2779746..2780303) Vibrio cholerae M66-2 7773852 YP_002811343.1 CDS VCM66_2596 NC_012578.1 2780440 2780991 R putative cell division protein FtsN complement(2780440..2780991) Vibrio cholerae M66-2 7773853 YP_002811344.1 CDS VCM66_2597 NC_012578.1 2781163 2782170 R negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR complement(2781163..2782170) Vibrio cholerae M66-2 7773854 YP_002811345.1 CDS priA NC_012578.1 2782476 2784680 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(2782476..2784680) Vibrio cholerae M66-2 7773855 YP_002811346.1 CDS rpmE NC_012578.1 2784935 2785153 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 2784935..2785153 Vibrio cholerae M66-2 7773856 YP_002811347.1 CDS VCM66_2600 NC_012578.1 2785251 2785394 D hypothetical protein 2785251..2785394 Vibrio cholerae M66-2 7773857 YP_002811348.1 CDS VCM66_2601 NC_012578.1 2785461 2786738 D putative malate oxidoreductase 2785461..2786738 Vibrio cholerae M66-2 7773858 YP_002811349.1 CDS metJ NC_012578.1 2786849 2787166 R when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ complement(2786849..2787166) Vibrio cholerae M66-2 7773859 YP_002811350.1 CDS metB NC_012578.1 2787434 2788600 D catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase 2787434..2788600 Vibrio cholerae M66-2 7773860 YP_002811351.1 CDS metL NC_012578.1 2788613 2791024 D multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 2788613..2791024 Vibrio cholerae M66-2 7773861 YP_002811352.1 CDS metF NC_012578.1 2791284 2792198 D MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 2791284..2792198 Vibrio cholerae M66-2 7773862 YP_002811353.1 CDS VCM66_2606 NC_012578.1 2792261 2792503 R hypothetical protein complement(2792261..2792503) Vibrio cholerae M66-2 7773863 YP_002811354.1 CDS VCM66_2607 NC_012578.1 2792552 2792656 D hypothetical protein 2792552..2792656 Vibrio cholerae M66-2 7773864 YP_002811355.1 CDS glpX NC_012578.1 2792824 2793831 D type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 2792824..2793831 Vibrio cholerae M66-2 7773865 YP_002811356.1 CDS pfkA NC_012578.1 2793908 2794903 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(2793908..2794903) Vibrio cholerae M66-2 7773866 YP_002811357.1 CDS fieF NC_012578.1 2795133 2796041 R member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F complement(2795133..2796041) Vibrio cholerae M66-2 7773867 YP_002811358.1 CDS cpxP NC_012578.1 2796239 2796742 R repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic repressor CpxP complement(2796239..2796742) Vibrio cholerae M66-2 7773868 YP_002811359.1 CDS cpxR NC_012578.1 2796930 2797616 D transcriptional regulator CpxR 2796930..2797616 Vibrio cholerae M66-2 7773869 YP_002811360.1 CDS cpxA NC_012578.1 2797616 2799010 D part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 2797616..2799010 Vibrio cholerae M66-2 7773870 YP_002811361.1 CDS sodA NC_012578.1 2799092 2799760 D superoxide dismutase, Mn 2799092..2799760 Vibrio cholerae M66-2 7773871 YP_002811362.1 CDS VCM66_2615 NC_012578.1 2799813 2800289 D rRNA methylase, SpoU family 2799813..2800289 Vibrio cholerae M66-2 7773872 YP_002811363.1 CDS fxsA NC_012578.1 2800323 2800808 R F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA complement(2800323..2800808) Vibrio cholerae M66-2 7773873 YP_002811364.1 CDS VCM66_2617 NC_012578.1 2800900 2801838 R GGDEF family protein complement(2800900..2801838) Vibrio cholerae M66-2 7773874 YP_002811365.1 CDS aspA NC_012578.1 2802083 2803534 D catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 2802083..2803534 Vibrio cholerae M66-2 7773875 YP_002811366.1 CDS dcuA NC_012578.1 2803614 2804969 D functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 2803614..2804969 Vibrio cholerae M66-2 7773876 YP_002811367.1 CDS dipZ NC_012578.1 2809121 2810923 D two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 2809121..2810923 Vibrio cholerae M66-2 7773967 YP_002811368.1 CDS VCM66_2622 NC_012578.1 2811096 2811725 D LuxR family transcriptional reguator 2811096..2811725 Vibrio cholerae M66-2 7773878 YP_002811369.1 CDS VCM66_2623 NC_012578.1 2811824 2813569 R the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter complement(2811824..2813569) Vibrio cholerae M66-2 7773879 YP_002811370.1 CDS VCM66_2624 NC_012578.1 2813948 2814214 D hypothetical protein 2813948..2814214 Vibrio cholerae M66-2 7773880 YP_002811371.1 CDS VCM66_2625 NC_012578.1 2814408 2815928 D putative sodium/solute symporter 2814408..2815928 Vibrio cholerae M66-2 7773881 YP_002811372.1 CDS VCM66_2626 NC_012578.1 2816026 2816697 R hypothetical protein complement(2816026..2816697) Vibrio cholerae M66-2 7773882 YP_002811373.1 CDS gmk NC_012578.1 2816999 2817688 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 2816999..2817688 Vibrio cholerae M66-2 7773883 YP_002811374.1 CDS rpoZ NC_012578.1 2817796 2818068 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 2817796..2818068 Vibrio cholerae M66-2 7773884 YP_002811375.1 CDS spoT NC_012578.1 2818100 2820217 D bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 2818100..2820217 Vibrio cholerae M66-2 7773885 YP_002811376.1 CDS recG NC_012578.1 2820336 2822414 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 2820336..2822414 Vibrio cholerae M66-2 7773886 YP_002811377.1 CDS VCM66_2632 NC_012578.1 2822723 2824165 D xanthine/uracil permease family protein 2822723..2824165 Vibrio cholerae M66-2 7773887 YP_002811378.1 CDS envZ NC_012578.1 2824190 2825506 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(2824190..2825506) Vibrio cholerae M66-2 7773888 YP_002811379.1 CDS ompR NC_012578.1 2825575 2826297 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(2825575..2826297) Vibrio cholerae M66-2 7773889 YP_002811380.1 CDS greB NC_012578.1 2826435 2826920 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB complement(2826435..2826920) Vibrio cholerae M66-2 7773890 YP_002811381.1 CDS VCM66_2636 NC_012578.1 2827165 2829486 D hypothetical protein 2827165..2829486 Vibrio cholerae M66-2 7773891 YP_002811382.1 CDS VCM66_2637 NC_012578.1 2829578 2830075 R hypothetical protein complement(2829578..2830075) Vibrio cholerae M66-2 7773892 YP_002811383.1 CDS bioH NC_012578.1 2830210 2831016 R bioH protein complement(2830210..2831016) Vibrio cholerae M66-2 7773893 YP_002811384.1 CDS VCM66_2639 NC_012578.1 2830907 2831767 D ComF-like protein 2830907..2831767 Vibrio cholerae M66-2 7773894 YP_002811385.1 CDS VCM66_2640 NC_012578.1 2831855 2832442 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; putative DNA uptake protein 2831855..2832442 Vibrio cholerae M66-2 7773895 YP_002811386.1 CDS nudE NC_012578.1 2832515 2833129 D ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 2832515..2833129 Vibrio cholerae M66-2 7773896 YP_002811387.1 CDS cysQ NC_012578.1 2833074 2833979 D cysQ protein 2833074..2833979 Vibrio cholerae M66-2 7773897 YP_002811388.1 CDS epsN NC_012578.1 2834031 2834789 R general secretion pathway protein N complement(2834031..2834789) Vibrio cholerae M66-2 7773898 YP_002811389.1 CDS epsM NC_012578.1 2834791 2835291 R cholera toxin secretion protein EpsM complement(2834791..2835291) Vibrio cholerae M66-2 7773899 YP_002811390.1 CDS epsL NC_012578.1 2835298 2836521 R general secretion pathway protein L complement(2835298..2836521) Vibrio cholerae M66-2 7773900 YP_002811391.1 CDS epsK NC_012578.1 2836478 2837488 R general secretion pathway protein K complement(2836478..2837488) Vibrio cholerae M66-2 7773901 YP_002811392.1 CDS epsJ NC_012578.1 2837478 2838143 R general secretion pathway protein J complement(2837478..2838143) Vibrio cholerae M66-2 7773902 YP_002811393.1 CDS epsI NC_012578.1 2838130 2838483 R general secretion pathway protein I complement(2838130..2838483) Vibrio cholerae M66-2 7773903 YP_002811394.1 CDS epsH NC_012578.1 2838473 2839057 R general secretion pathway protein H complement(2838473..2839057) Vibrio cholerae M66-2 7773904 YP_002811395.1 CDS epsG NC_012578.1 2839091 2839531 R general secretion pathway protein G complement(2839091..2839531) Vibrio cholerae M66-2 7773905 YP_002811396.1 CDS epsF NC_012578.1 2839572 2840792 R general secretion pathway protein F complement(2839572..2840792) Vibrio cholerae M66-2 7773906 YP_002811397.1 CDS epsE NC_012578.1 2840792 2842303 R general secretion pathway protein E complement(2840792..2842303) Vibrio cholerae M66-2 7773907 YP_002811398.1 CDS gspD NC_012578.1 2842300 2844324 R general secretion pathway protein D complement(2842300..2844324) Vibrio cholerae M66-2 7773908 YP_002811399.1 CDS epsC NC_012578.1 2844370 2845287 R general secretion pathway protein C complement(2844370..2845287) Vibrio cholerae M66-2 7773909 YP_002811400.1 CDS VCM66_2655 NC_012578.1 2845511 2845894 D Heat shock protein 15 2845511..2845894 Vibrio cholerae M66-2 7773910 YP_002811401.1 CDS hslO NC_012578.1 2845913 2846803 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2845913..2846803 Vibrio cholerae M66-2 7773911 YP_002811402.1 CDS VCM66_2657 NC_012578.1 2846942 2847091 R hypothetical protein complement(2846942..2847091) Vibrio cholerae M66-2 7773912 YP_002811403.1 CDS pckA NC_012578.1 2847140 2848768 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 2847140..2848768 Vibrio cholerae M66-2 7773913 YP_002811404.1 CDS VCM66_2659 NC_012578.1 2848955 2850841 D hypothetical protein 2848955..2850841 Vibrio cholerae M66-2 7773914 YP_002811405.1 CDS VCM66_2660 NC_012578.1 2850883 2851815 R hypothetical protein complement(2850883..2851815) Vibrio cholerae M66-2 7773915 YP_002811406.1 CDS VCM66_2661 NC_012578.1 2851882 2852316 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(2851882..2852316) Vibrio cholerae M66-2 7773916 YP_002811407.1 CDS rbn NC_012578.1 2852334 2853227 R RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN complement(2852334..2853227) Vibrio cholerae M66-2 7773917 YP_002811408.1 CDS VCM66_2663 NC_012578.1 2853254 2853808 R hypothetical protein complement(2853254..2853808) Vibrio cholerae M66-2 7773918 YP_002811409.1 CDS typA NC_012578.1 2853891 2855720 R GTP-binding protein TypA complement(2853891..2855720) Vibrio cholerae M66-2 7773919 YP_002811410.1 CDS VCM66_2665 NC_012578.1 2855740 2856063 R hypothetical protein complement(2855740..2856063) Vibrio cholerae M66-2 7773920 YP_002811411.1 CDS glnA NC_012578.1 2856208 2857617 D forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 2856208..2857617 Vibrio cholerae M66-2 7773921 YP_002811412.1 CDS VCM66_2667 NC_012578.1 2857795 2858385 D hypothetical protein 2857795..2858385 Vibrio cholerae M66-2 7773922 YP_002811413.1 CDS glnL NC_012578.1 2858518 2859582 D sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 2858518..2859582 Vibrio cholerae M66-2 7773923 YP_002811414.1 CDS ntrC NC_012578.1 2859586 2860992 D nitrogen regulation protein NR(I) 2859586..2860992 Vibrio cholerae M66-2 7773924 YP_002811415.1 CDS VCM66_2670 NC_012578.1 2861033 2863582 D GGDEF/EAL family protein 2861033..2863582 Vibrio cholerae M66-2 7773925 YP_002811416.1 CDS add NC_012578.1 2863674 2864678 D catalyzes the formation of inosine from adenosine; adenosine deaminase 2863674..2864678 Vibrio cholerae M66-2 7773926 YP_002811417.1 CDS VCM66_2674 NC_012578.1 2870710 2870856 R hypothetical protein complement(2870710..2870856) Vibrio cholerae M66-2 7773974 YP_002811418.1 CDS hemG NC_012578.1 2870831 2871355 R catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase complement(2870831..2871355) Vibrio cholerae M66-2 7773928 YP_002811419.1 CDS trkH-2 NC_012578.1 2871378 2872835 R potassium uptake protein TrkH complement(2871378..2872835) Vibrio cholerae M66-2 7773929 YP_002811420.1 CDS VCM66_2677 NC_012578.1 2872855 2873487 R hypothetical protein complement(2872855..2873487) Vibrio cholerae M66-2 7773930 YP_002811421.1 CDS fadB NC_012578.1 2873698 2875869 D includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 2873698..2875869 Vibrio cholerae M66-2 7773931 YP_002811422.1 CDS fadA NC_012578.1 2875895 2877058 D FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 2875895..2877058 Vibrio cholerae M66-2 7773932 YP_002811423.1 CDS VCM66_2680 NC_012578.1 2877125 2878033 R putative DNA-binding transcriptional regulator complement(2877125..2878033) Vibrio cholerae M66-2 7773933 YP_002811424.1 CDS VCM66_2681 NC_012578.1 2878162 2879391 D uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 2878162..2879391 Vibrio cholerae M66-2 7773934 YP_002811425.1 CDS glmU NC_012578.1 2879451 2880812 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(2879451..2880812) Vibrio cholerae M66-2 7773935 YP_002811426.1 CDS atpC NC_012578.1 2881059 2881481 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(2881059..2881481) Vibrio cholerae M66-2 7773936 YP_002811427.1 CDS atpD NC_012578.1 2881500 2882903 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(2881500..2882903) Vibrio cholerae M66-2 7773937 YP_002811428.1 CDS atpG NC_012578.1 2882938 2883804 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(2882938..2883804) Vibrio cholerae M66-2 7773938 YP_002811429.1 CDS atpA NC_012578.1 2883849 2885420 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(2883849..2885420) Vibrio cholerae M66-2 7773939 YP_002811430.1 CDS atpH NC_012578.1 2885404 2885937 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(2885404..2885937) Vibrio cholerae M66-2 7773940 YP_002811431.1 CDS atpF NC_012578.1 2885952 2886422 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(2885952..2886422) Vibrio cholerae M66-2 7773941 YP_002811432.1 CDS atpE NC_012578.1 2886496 2886753 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(2886496..2886753) Vibrio cholerae M66-2 7773942 YP_002811433.1 CDS atpB NC_012578.1 2886797 2887609 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(2886797..2887609) Vibrio cholerae M66-2 7773943 YP_002811434.1 CDS atpI NC_012578.1 2887618 2888007 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(2887618..2888007) Vibrio cholerae M66-2 7773944 YP_002811435.1 CDS VCM66_2692 NC_012578.1 2888197 2889078 R ParB family protein complement(2888197..2889078) Vibrio cholerae M66-2 7773945 YP_002811436.1 CDS VCM66_2693 NC_012578.1 2889105 2889878 R ParA family protein complement(2889105..2889878) Vibrio cholerae M66-2 7773946 YP_002811437.1 CDS gidB NC_012578.1 2889893 2890525 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(2889893..2890525) Vibrio cholerae M66-2 7773947 YP_002811438.1 CDS gidA NC_012578.1 2890525 2892420 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(2890525..2892420) Vibrio cholerae M66-2 7773948 YP_002811645.1 CDS VCM66_A0001 NC_012580.1 112 246 R hypothetical protein complement(112..246) Vibrio cholerae M66-2 7781299 YP_002811646.1 CDS VCM66_A0002 NC_012580.1 1134 3110 D hypothetical protein 1134..3110 Vibrio cholerae M66-2 7781300 YP_002811647.1 CDS VCM66_A0003 NC_012580.1 3330 3944 R hypothetical protein complement(3330..3944) Vibrio cholerae M66-2 7781301 YP_002811648.1 CDS VCM66_A0004 NC_012580.1 4154 4351 D hypothetical protein 4154..4351 Vibrio cholerae M66-2 7781302 YP_002811649.1 CDS VCM66_A0005 NC_012580.1 4445 4723 D hypothetical protein 4445..4723 Vibrio cholerae M66-2 7781303 YP_002811650.1 CDS VCM66_A0006 NC_012580.1 4811 5530 D hypothetical protein 4811..5530 Vibrio cholerae M66-2 7781304 YP_002811651.1 CDS VCM66_A0007 NC_012580.1 5573 6520 D putative 3-hydroxyisobutyrate dehydrogenase 5573..6520 Vibrio cholerae M66-2 7781305 YP_002811652.1 CDS VCM66_A0008 NC_012580.1 6624 8285 R methyl-accepting chemotaxis protein complement(6624..8285) Vibrio cholerae M66-2 7781306 YP_002811653.1 CDS VCM66_A0010 NC_012580.1 8484 8921 D hypothetical protein 8484..8921 Vibrio cholerae M66-2 7781307 YP_002811654.1 CDS malT NC_012580.1 8987 11737 R Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT complement(8987..11737) Vibrio cholerae M66-2 7781308 YP_002811655.1 CDS malP NC_012580.1 12257 14710 D maltodextrin phosphorylase 12257..14710 Vibrio cholerae M66-2 7781309 YP_002811656.1 CDS malQ NC_012580.1 14796 16976 D amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 14796..16976 Vibrio cholerae M66-2 7781310 YP_002811657.1 CDS glgB NC_012580.1 17230 19371 D catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching enzyme 17230..19371 Vibrio cholerae M66-2 7781311 YP_002811658.1 CDS hcp-2 NC_012580.1 19766 20284 D hcp protein 19766..20284 Vibrio cholerae M66-2 7781312 YP_002811659.1 CDS vgrG-2 NC_012580.1 20412 22496 D vgrG protein 20412..22496 Vibrio cholerae M66-2 7781313 YP_002811660.1 CDS VCM66_A0018 NC_012580.1 22496 23383 D hypothetical protein 22496..23383 Vibrio cholerae M66-2 7781314 YP_002811661.1 CDS VCM66_A0019 NC_012580.1 23380 26646 D hypothetical protein 23380..26646 Vibrio cholerae M66-2 7781315 YP_002811662.1 CDS VCM66_A0020 NC_012580.1 26647 27375 D hypothetical protein 26647..27375 Vibrio cholerae M66-2 7781316 YP_002811663.1 CDS VCM66_A0021 NC_012580.1 27478 27879 D glutathione S-transfersae-related protein 27478..27879 Vibrio cholerae M66-2 7781317 YP_002811664.1 CDS VCM66_A0022 NC_012580.1 28052 29092 R hypothetical protein complement(28052..29092) Vibrio cholerae M66-2 7781318 YP_002811665.1 CDS VCM66_A0023 NC_012580.1 29208 30200 R hypothetical protein complement(29208..30200) Vibrio cholerae M66-2 7781319 YP_002811666.1 CDS VCM66_A0024 NC_012580.1 30478 31866 D transporter, NadC family 30478..31866 Vibrio cholerae M66-2 7781320 YP_002811667.1 CDS VCM66_A0025 NC_012580.1 31962 32597 R hypothetical protein complement(31962..32597) Vibrio cholerae M66-2 7781321 YP_002811668.1 CDS chiA-2 NC_012580.1 33029 35575 D chitinase 33029..35575 Vibrio cholerae M66-2 7781322 YP_002811669.1 CDS VCM66_A0028 NC_012580.1 35941 36675 D putative transcriptional regulator 35941..36675 Vibrio cholerae M66-2 7781323 YP_002811670.1 CDS VCM66_A0029 NC_012580.1 36676 37518 D hypothetical protein 36676..37518 Vibrio cholerae M66-2 7781324 YP_002811671.1 CDS VCM66_A0030 NC_012580.1 37639 39204 R methyl-accepting chemotaxis protein complement(37639..39204) Vibrio cholerae M66-2 7781325 YP_002811672.1 CDS VCM66_A0031 NC_012580.1 39302 39862 R hypothetical protein complement(39302..39862) Vibrio cholerae M66-2 7781326 YP_002811673.1 CDS VCM66_A0032 NC_012580.1 40271 42145 D hypothetical protein 40271..42145 Vibrio cholerae M66-2 7781327 YP_002811674.1 CDS VCM66_A0033 NC_012580.1 42205 43077 R hypothetical protein complement(42205..43077) Vibrio cholerae M66-2 7781328 YP_002811675.1 CDS VCM66_A0034 NC_012580.1 43193 44017 D putative phosphatidylglycerophosphatase B 43193..44017 Vibrio cholerae M66-2 7781329 YP_002811676.1 CDS VCM66_A0035 NC_012580.1 44071 45288 R involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT complement(44071..45288) Vibrio cholerae M66-2 7781330 YP_002811677.1 CDS VCM66_A0036 NC_012580.1 45630 46082 R hypothetical protein complement(45630..46082) Vibrio cholerae M66-2 7781331 YP_002811678.1 CDS VCM66_A0037 NC_012580.1 46096 46677 R Sco1-related protein complement(46096..46677) Vibrio cholerae M66-2 7781332 YP_002811679.1 CDS VCM66_A0038 NC_012580.1 46674 47096 R hypothetical protein complement(46674..47096) Vibrio cholerae M66-2 7781333 YP_002811680.1 CDS VCM66_A0039 NC_012580.1 47295 48221 R hypothetical protein complement(47295..48221) Vibrio cholerae M66-2 7781334 YP_002811681.1 CDS glts NC_012580.1 48760 49986 D sodium/glutamate symporter 48760..49986 Vibrio cholerae M66-2 7781335 YP_002811682.1 CDS VCM66_A0041 NC_012580.1 50065 50823 R hypothetical protein complement(50065..50823) Vibrio cholerae M66-2 7781336 YP_002811683.1 CDS VCM66_A0042 NC_012580.1 50955 51239 D hypothetical protein 50955..51239 Vibrio cholerae M66-2 7781337 YP_002811684.1 CDS VCM66_A0043 NC_012580.1 51472 54726 D putative tricorn protease 51472..54726 Vibrio cholerae M66-2 7781338 YP_002811685.1 CDS VCM66_A0044 NC_012580.1 54718 54840 R hypothetical protein complement(54718..54840) Vibrio cholerae M66-2 7781339 YP_002811686.1 CDS VCM66_A0045 NC_012580.1 54921 56051 R hypothetical protein complement(54921..56051) Vibrio cholerae M66-2 7781340 YP_002811687.1 CDS VCM66_A0046 NC_012580.1 56051 56440 R hypothetical protein complement(56051..56440) Vibrio cholerae M66-2 7781341 YP_002811688.1 CDS VCM66_A0047 NC_012580.1 56575 58182 R GGDEF family protein complement(56575..58182) Vibrio cholerae M66-2 7781342 YP_002811689.1 CDS VCM66_A0048 NC_012580.1 58136 59659 R hypothetical protein complement(58136..59659) Vibrio cholerae M66-2 7781343 YP_002811690.1 CDS VCM66_A0049 NC_012580.1 59778 61340 R hypothetical protein complement(59778..61340) Vibrio cholerae M66-2 7781344 YP_002811691.1 CDS deoD-2 NC_012580.1 61312 62049 R catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase complement(61312..62049) Vibrio cholerae M66-2 7781345 YP_002811692.1 CDS VCM66_A0051 NC_012580.1 62108 62287 R hypothetical protein complement(62108..62287) Vibrio cholerae M66-2 7781346 YP_002811693.1 CDS VCM66_A0052 NC_012580.1 62329 63297 D hypothetical protein 62329..63297 Vibrio cholerae M66-2 7781347 YP_002811694.1 CDS VCM66_A0053 NC_012580.1 63287 64084 D transcriptional regulator, MerR family 63287..64084 Vibrio cholerae M66-2 7781348 YP_002811695.1 CDS phrB-2 NC_012580.1 64094 65503 D deoxyribodipyrimidine photolyase 64094..65503 Vibrio cholerae M66-2 7781349 YP_002811696.1 CDS VCM66_A0055 NC_012580.1 65512 66432 D hypothetical protein 65512..66432 Vibrio cholerae M66-2 7781350 YP_002811697.1 CDS lpp NC_012580.1 66518 66877 R major outer membrane lipoprotein complement(66518..66877) Vibrio cholerae M66-2 7781351 YP_002811698.1 CDS VCM66_A0058 NC_012580.1 67296 68654 D ATP-dependent RNA helicase, DEAD box family 67296..68654 Vibrio cholerae M66-2 7781352 YP_002811699.1 CDS VCM66_A0059 NC_012580.1 68651 68761 R hypothetical protein complement(68651..68761) Vibrio cholerae M66-2 7781353 YP_002811700.1 CDS ptrB NC_012580.1 68867 70864 D protease II 68867..70864 Vibrio cholerae M66-2 7781354 YP_002811701.1 CDS hutR NC_012580.1 70864 73005 D heme receptor HutR 70864..73005 Vibrio cholerae M66-2 7781355 YP_002811702.1 CDS VCM66_A0062 NC_012580.1 73015 75321 D hypothetical protein 73015..75321 Vibrio cholerae M66-2 7781356 YP_002811703.1 CDS VCM66_A0063 NC_012580.1 75318 76760 D hypothetical protein 75318..76760 Vibrio cholerae M66-2 7781357 YP_002811704.1 CDS VCM66_A0064 NC_012580.1 76757 77317 D hypothetical protein 76757..77317 Vibrio cholerae M66-2 7781358 YP_002811705.1 CDS VCM66_A0065 NC_012580.1 77451 79094 R methyl-accepting chemotaxis protein complement(77451..79094) Vibrio cholerae M66-2 7781359 YP_002811706.1 CDS VCM66_A0066 NC_012580.1 79241 79339 D hypothetical protein 79241..79339 Vibrio cholerae M66-2 7781360 YP_002811707.1 CDS pstS NC_012580.1 79387 80286 D phosphate ABC transporter substrate-binding protein 79387..80286 Vibrio cholerae M66-2 7781361 YP_002811708.1 CDS pstC-2 NC_012580.1 80301 81284 D phosphate ABC transporter permease 80301..81284 Vibrio cholerae M66-2 7781362 YP_002811709.1 CDS pstA-2 NC_012580.1 81284 82153 D phosphate ABC transporter permease 81284..82153 Vibrio cholerae M66-2 7781363 YP_002811710.1 CDS pstB-2 NC_012580.1 82182 82937 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein 82182..82937 Vibrio cholerae M66-2 7781364 YP_002811711.1 CDS VCM66_A0072 NC_012580.1 84081 84548 R hypothetical protein complement(84081..84548) Vibrio cholerae M66-2 7781366 YP_002811712.1 CDS VCM66_A0073 NC_012580.1 84430 84675 D putative Hemolysin secretion protein D 84430..84675 Vibrio cholerae M66-2 7781367 YP_002811713.1 CDS VCM66_A0074 NC_012580.1 84839 86215 R hypothetical protein complement(84839..86215) Vibrio cholerae M66-2 7781368 YP_002811714.1 CDS VCM66_A0075 NC_012580.1 86650 88311 R sulfate permease family protein complement(86650..88311) Vibrio cholerae M66-2 7781369 YP_002811715.1 CDS VCM66_A0076 NC_012580.1 88616 88948 D hypothetical protein 88616..88948 Vibrio cholerae M66-2 7781370 YP_002811716.1 CDS VCM66_A0077 NC_012580.1 89140 90432 D hypothetical protein 89140..90432 Vibrio cholerae M66-2 7781371 YP_002811717.1 CDS VCM66_A0078 NC_012580.1 90550 92373 R GGDEF family protein complement(90550..92373) Vibrio cholerae M66-2 7781372 YP_002811718.1 CDS VCM66_A0080 NC_012580.1 92596 93483 R LysR family transcriptional regulator complement(92596..93483) Vibrio cholerae M66-2 7781373 YP_002811719.1 CDS emrD-1 NC_012580.1 93573 94784 D multidrug resistance protein D 93573..94784 Vibrio cholerae M66-2 7781374 YP_002811720.1 CDS soxR NC_012580.1 94826 95272 R soxR protein complement(94826..95272) Vibrio cholerae M66-2 7781375 YP_002811721.1 CDS VCM66_A0083 NC_012580.1 95451 96653 D hypothetical protein 95451..96653 Vibrio cholerae M66-2 7781376 YP_002811722.1 CDS VCM66_A0084 NC_012580.1 96754 97134 D hypothetical protein 96754..97134 Vibrio cholerae M66-2 7781377 YP_002811723.1 CDS VCM66_A0085 NC_012580.1 97208 97372 D hypothetical protein 97208..97372 Vibrio cholerae M66-2 7781378 YP_002811724.1 CDS gltP-2 NC_012580.1 97501 98811 R proton/glutamate symporter complement(97501..98811) Vibrio cholerae M66-2 7781379 YP_002811725.1 CDS VCM66_A0087 NC_012580.1 98839 98967 D hypothetical protein 98839..98967 Vibrio cholerae M66-2 7781380 YP_002811726.1 CDS VCM66_A0088 NC_012580.1 99067 99960 R hypothetical protein complement(99067..99960) Vibrio cholerae M66-2 7781381 YP_002811727.1 CDS VCM66_A0089 NC_012580.1 100190 100486 D hypothetical protein 100190..100486 Vibrio cholerae M66-2 7781382 YP_002811728.1 CDS VCM66_A0090 NC_012580.1 100657 101286 R hypothetical protein complement(100657..101286) Vibrio cholerae M66-2 7781383 YP_002811729.1 CDS VCM66_A0091 NC_012580.1 101386 101559 D hypothetical protein 101386..101559 Vibrio cholerae M66-2 7781384 YP_002811730.1 CDS VCM66_A0092 NC_012580.1 101787 102143 D hypothetical protein 101787..102143 Vibrio cholerae M66-2 7781385 YP_002811731.1 CDS VCM66_A0093 NC_012580.1 102412 103110 D hypothetical protein 102412..103110 Vibrio cholerae M66-2 7781386 YP_002811732.1 CDS VCM66_A0094 NC_012580.1 103153 104376 D hypothetical protein 103153..104376 Vibrio cholerae M66-2 7781387 YP_002811733.1 CDS VCM66_A0095 NC_012580.1 104389 105105 R hypothetical protein complement(104389..105105) Vibrio cholerae M66-2 7781388 YP_002811734.1 CDS pncB NC_012580.1 105504 106811 D catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 105504..106811 Vibrio cholerae M66-2 7781389 YP_002811735.1 CDS VCM66_A0097 NC_012580.1 106842 107882 D oxidoreductase, Gfo/Idh/MocA family 106842..107882 Vibrio cholerae M66-2 7781390 YP_002811736.1 CDS pspE NC_012580.1 107919 108290 R phage shock protein E complement(107919..108290) Vibrio cholerae M66-2 7781391 YP_002811737.1 CDS VCM66_A0099 NC_012580.1 108290 109846 R hypothetical protein complement(108290..109846) Vibrio cholerae M66-2 7781392 YP_002811738.1 CDS VCM66_A0100 NC_012580.1 110022 110681 R CbbY family protein complement(110022..110681) Vibrio cholerae M66-2 7781393 YP_002811739.1 CDS VCM66_A0101 NC_012580.1 110862 112640 D sulfate permease family protein 110862..112640 Vibrio cholerae M66-2 7781394 YP_002811740.1 CDS rluA-2 NC_012580.1 112682 114361 R ribosomal large subunit pseudouridine synthase A complement(112682..114361) Vibrio cholerae M66-2 7781395 YP_002811741.1 CDS VCM66_A0103 NC_012580.1 115133 115417 D hypothetical protein 115133..115417 Vibrio cholerae M66-2 7781396 YP_002811742.1 CDS VCM66_A0104 NC_012580.1 115362 116405 D hypothetical protein 115362..116405 Vibrio cholerae M66-2 7781397 YP_002811743.1 CDS VCM66_A0105 NC_012580.1 116837 117343 D hypothetical protein 116837..117343 Vibrio cholerae M66-2 7781398 YP_002811744.1 CDS VCM66_A0106 NC_012580.1 117384 118862 D hypothetical protein 117384..118862 Vibrio cholerae M66-2 7781399 YP_002811745.1 CDS VCM66_A0107 NC_012580.1 118865 119302 D hypothetical protein 118865..119302 Vibrio cholerae M66-2 7781400 YP_002811746.1 CDS VCM66_A0108 NC_012580.1 119308 121077 D hypothetical protein 119308..121077 Vibrio cholerae M66-2 7781401 YP_002811747.1 CDS VCM66_A0109 NC_012580.1 121041 122057 D hypothetical protein 121041..122057 Vibrio cholerae M66-2 7781402 YP_002811748.1 CDS VCM66_A0110 NC_012580.1 122060 123547 D hypothetical protein 122060..123547 Vibrio cholerae M66-2 7781403 YP_002811749.1 CDS VCM66_A0111 NC_012580.1 123550 124026 D hypothetical protein 123550..124026 Vibrio cholerae M66-2 7781404 YP_002811750.1 CDS VCM66_A0112 NC_012580.1 124033 125367 D hypothetical protein 124033..125367 Vibrio cholerae M66-2 7781405 YP_002811751.1 CDS VCM66_A0113 NC_012580.1 125370 126143 D hypothetical protein 125370..126143 Vibrio cholerae M66-2 7781406 YP_002811752.1 CDS clpB-2 NC_012580.1 126169 128778 D clpB protein 126169..128778 Vibrio cholerae M66-2 7781407 YP_002811753.1 CDS VCM66_A0115 NC_012580.1 128781 130373 D sigma-54 dependent transcriptional regulator 128781..130373 Vibrio cholerae M66-2 7781408 YP_002811754.1 CDS VCM66_A0116 NC_012580.1 130343 131026 D hypothetical protein 130343..131026 Vibrio cholerae M66-2 7781409 YP_002811755.1 CDS VCM66_A0117 NC_012580.1 131036 132445 D hypothetical protein 131036..132445 Vibrio cholerae M66-2 7781410 YP_002811756.1 CDS VCM66_A0118 NC_012580.1 132461 136006 D IcmF-related protein 132461..136006 Vibrio cholerae M66-2 7781411 YP_002811757.1 CDS VCM66_A0119 NC_012580.1 136054 137319 D hypothetical protein 136054..137319 Vibrio cholerae M66-2 7781412 YP_002811758.1 CDS VCM66_A0120 NC_012580.1 137370 137612 D hypothetical protein 137370..137612 Vibrio cholerae M66-2 7781413 YP_002811759.1 CDS vgrG-3 NC_012580.1 137572 140625 D vgrG protein 137572..140625 Vibrio cholerae M66-2 7781414 YP_002811760.1 CDS VCM66_A0122 NC_012580.1 140622 140990 D hypothetical protein 140622..140990 Vibrio cholerae M66-2 7781415 YP_002811761.1 CDS VCM66_A0123 NC_012580.1 141138 141398 R hypothetical protein complement(141138..141398) Vibrio cholerae M66-2 7781416 YP_002811762.1 CDS VCM66_A0124 NC_012580.1 141373 141582 D hypothetical protein 141373..141582 Vibrio cholerae M66-2 7781417 YP_002811763.1 CDS rbsD NC_012580.1 141631 142101 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 141631..142101 Vibrio cholerae M66-2 7781418 YP_002811764.1 CDS rbsA NC_012580.1 142128 143630 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP binding protein 142128..143630 Vibrio cholerae M66-2 7781419 YP_002811765.1 CDS rbsC NC_012580.1 143627 144628 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease protein 143627..144628 Vibrio cholerae M66-2 7781420 YP_002811766.1 CDS rbsB NC_012580.1 144683 145567 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 144683..145567 Vibrio cholerae M66-2 7781421 YP_002811767.1 CDS rbsK NC_012580.1 145706 146626 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 145706..146626 Vibrio cholerae M66-2 7781422 YP_002811768.1 CDS rbsR NC_012580.1 146637 147641 D ribose operon repressor 146637..147641 Vibrio cholerae M66-2 7781423 YP_002811769.1 CDS pnuC NC_012580.1 147767 148501 D pnuC protein 147767..148501 Vibrio cholerae M66-2 7781424 YP_002811770.1 CDS udp-2 NC_012580.1 148498 149229 D uridine phosphorylase 148498..149229 Vibrio cholerae M66-2 7781425 YP_002811771.1 CDS VCM66_A0133 NC_012580.1 149369 150049 D putative cyclic nucleotide binding protein 149369..150049 Vibrio cholerae M66-2 7781426 YP_002811772.1 CDS glpQ NC_012580.1 150102 151217 R hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase complement(150102..151217) Vibrio cholerae M66-2 7781427 YP_002811773.1 CDS glpT NC_012580.1 151323 152732 R catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter complement(151323..152732) Vibrio cholerae M66-2 7781428 YP_002811774.1 CDS VCM66_A0136 NC_012580.1 152828 152935 R hypothetical protein complement(152828..152935) Vibrio cholerae M66-2 7781429 YP_002811775.1 CDS VCM66_A0137 NC_012580.1 153107 153454 R hypothetical protein complement(153107..153454) Vibrio cholerae M66-2 7781430 YP_002811776.1 CDS VCM66_A0138 NC_012580.1 153862 155070 D spindolin-related protein 153862..155070 Vibrio cholerae M66-2 7781431 YP_002811777.1 CDS VCM66_A0139 NC_012580.1 155185 157239 R putative C4-dicarboxylate transport sensor protein complement(155185..157239) Vibrio cholerae M66-2 7781432 YP_002811778.1 CDS dctD-2 NC_012580.1 157529 158881 D C4-dicarboxylate transport transcriptional regulatory protein 157529..158881 Vibrio cholerae M66-2 7781433 YP_002811779.1 CDS VCM66_A0141 NC_012580.1 158947 159057 D hypothetical protein 158947..159057 Vibrio cholerae M66-2 7781434 YP_002811780.1 CDS VCM66_A0142 NC_012580.1 159135 160190 D immunogenic protein 159135..160190 Vibrio cholerae M66-2 7781435 YP_002811781.1 CDS VCM66_A0143 NC_012580.1 160159 160287 R hypothetical protein complement(160159..160287) Vibrio cholerae M66-2 7781436 YP_002811782.1 CDS VCM66_A0144 NC_012580.1 160340 162505 D putative TRAP transporter large permease protein 160340..162505 Vibrio cholerae M66-2 7781437 YP_002811783.1 CDS VCM66_A0145 NC_012580.1 162502 163713 D catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 162502..163713 Vibrio cholerae M66-2 7781438 YP_002811784.1 CDS VCM66_A0146 NC_012580.1 163822 167829 D TagA-related protein 163822..167829 Vibrio cholerae M66-2 7781439 YP_002811785.1 CDS VCM66_A0147 NC_012580.1 167854 167961 D hypothetical protein 167854..167961 Vibrio cholerae M66-2 7781440 YP_002811786.1 CDS def-2 NC_012580.1 167977 168483 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 167977..168483 Vibrio cholerae M66-2 7781441 YP_002811787.1 CDS VCM66_A0149 NC_012580.1 168612 169964 D putative oxidoreductase 168612..169964 Vibrio cholerae M66-2 7781442 YP_002811788.1 CDS VCM66_A0150 NC_012580.1 170039 170362 R subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit G complement(170039..170362) Vibrio cholerae M66-2 7781443 YP_002811789.1 CDS VCM66_A0151 NC_012580.1 170362 170673 R subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; putative monovalent cation/H+ antiporter subunit F complement(170362..170673) Vibrio cholerae M66-2 7781444 YP_002811790.1 CDS VCM66_A0152 NC_012580.1 170633 171109 R hypothetical protein complement(170633..171109) Vibrio cholerae M66-2 7781445 YP_002811791.1 CDS VCM66_A0153 NC_012580.1 171106 172602 R putative NADH dehydrogenase complement(171106..172602) Vibrio cholerae M66-2 7781446 YP_002811792.1 CDS VCM66_A0154 NC_012580.1 172599 172952 R subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; putative monovalent cation/H+ antiporter subunit C complement(172599..172952) Vibrio cholerae M66-2 7781447 YP_002811793.1 CDS VCM66_A0155 NC_012580.1 172952 175627 R putative NADH dehydrogenase complement(172952..175627) Vibrio cholerae M66-2 7781448 YP_002811794.1 CDS VCM66_A0156 NC_012580.1 175774 175974 R hypothetical protein complement(175774..175974) Vibrio cholerae M66-2 7781449 YP_002811795.1 CDS VCM66_A0157 NC_012580.1 176046 176987 R hypothetical protein complement(176046..176987) Vibrio cholerae M66-2 7781450 YP_002811796.1 CDS mtr NC_012580.1 177183 178418 R tryptophan-specific transport protein complement(177183..178418) Vibrio cholerae M66-2 7781451 YP_002811797.1 CDS tnaA NC_012580.1 178497 179915 R tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase complement(178497..179915) Vibrio cholerae M66-2 7781452 YP_002811798.1 CDS VCM66_A0160 NC_012580.1 180481 180687 R hypothetical protein complement(180481..180687) Vibrio cholerae M66-2 7781453 YP_002811799.1 CDS VCM66_A0161 NC_012580.1 180696 180908 D hypothetical protein 180696..180908 Vibrio cholerae M66-2 7781454 YP_002811800.1 CDS VCM66_A0162 NC_012580.1 180978 181562 R hypothetical protein complement(180978..181562) Vibrio cholerae M66-2 7781455 YP_002811801.1 CDS VCM66_A0163 NC_012580.1 181869 184001 D GGDEF family protein 181869..184001 Vibrio cholerae M66-2 7781456 YP_002811802.1 CDS cspA NC_012580.1 184247 184459 D cold shock transcriptional regulator CspA 184247..184459 Vibrio cholerae M66-2 7781457 YP_002811803.1 CDS VCM66_A0165 NC_012580.1 184762 185550 R hypothetical protein complement(184762..185550) Vibrio cholerae M66-2 7781458 YP_002811804.1 CDS VCM66_A0166 NC_012580.1 185639 187291 R hypothetical protein complement(185639..187291) Vibrio cholerae M66-2 7781459 YP_002811805.1 CDS VCM66_A0167 NC_012580.1 187285 189171 R hypothetical protein complement(187285..189171) Vibrio cholerae M66-2 7781460 YP_002811806.1 CDS VCM66_A0168 NC_012580.1 189173 190129 R hypothetical protein complement(189173..190129) Vibrio cholerae M66-2 7781461 YP_002811807.1 CDS VCM66_A0169 NC_012580.1 190116 190604 R hypothetical protein complement(190116..190604) Vibrio cholerae M66-2 7781462 YP_002811808.1 CDS VCM66_A0170 NC_012580.1 190601 191533 R hypothetical protein complement(190601..191533) Vibrio cholerae M66-2 7781463 YP_002811809.1 CDS VCM66_A0171 NC_012580.1 191537 192493 R MoxR-related protein complement(191537..192493) Vibrio cholerae M66-2 7781464 YP_002811810.1 CDS VCM66_A0172 NC_012580.1 192795 194711 D methyl-accepting chemotaxis protein 192795..194711 Vibrio cholerae M66-2 7781465 YP_002811811.1 CDS VCM66_A0173 NC_012580.1 194768 194971 D hypothetical protein 194768..194971 Vibrio cholerae M66-2 7781466 YP_002811812.1 CDS frnE NC_012580.1 195247 195900 R frnE protein complement(195247..195900) Vibrio cholerae M66-2 7781467 YP_002811813.1 CDS VCM66_A0175 NC_012580.1 196547 197755 D NupC family protein 196547..197755 Vibrio cholerae M66-2 7781468 YP_002811814.1 CDS pepT NC_012580.1 197990 199222 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 197990..199222 Vibrio cholerae M66-2 7781469 YP_002811815.1 CDS VCM66_A0177 NC_012580.1 199394 200269 D hypothetical protein 199394..200269 Vibrio cholerae M66-2 7781470 YP_002811816.1 CDS VCM66_A0178 NC_012580.1 200266 201858 R Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcription regulator complement(200266..201858) Vibrio cholerae M66-2 7781471 YP_002811817.1 CDS hmpA NC_012580.1 202049 203233 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 202049..203233 Vibrio cholerae M66-2 7781472 YP_002811818.1 CDS VCM66_A0180 NC_012580.1 203377 203586 R cold shock DNA-binding domain protein complement(203377..203586) Vibrio cholerae M66-2 7781473 YP_002811819.1 CDS VCM66_A0181 NC_012580.1 203945 204172 D hypothetical protein 203945..204172 Vibrio cholerae M66-2 7781474 YP_002811820.1 CDS VCM66_A0182 NC_012580.1 204560 204937 D hypothetical protein 204560..204937 Vibrio cholerae M66-2 7781475 YP_002811821.1 CDS VCM66_A0183 NC_012580.1 204963 205094 R hypothetical protein complement(204963..205094) Vibrio cholerae M66-2 7781476 YP_002811822.1 CDS VCM66_A0184 NC_012580.1 205172 205450 D hypothetical protein 205172..205450 Vibrio cholerae M66-2 7781477 YP_002811823.1 CDS VCM66_A0185 NC_012580.1 205537 206541 D response regulator 205537..206541 Vibrio cholerae M66-2 7781478 YP_002811824.1 CDS VCM66_A0186 NC_012580.1 206541 206987 D hypothetical protein 206541..206987 Vibrio cholerae M66-2 7781479 YP_002811825.1 CDS VCM66_A0187 NC_012580.1 207025 208509 D hypothetical protein 207025..208509 Vibrio cholerae M66-2 7781480 YP_002811826.1 CDS ldhA NC_012580.1 208498 209493 R D-lactate dehydrogenase complement(208498..209493) Vibrio cholerae M66-2 7781481 YP_002811827.1 CDS VCM66_A0189 NC_012580.1 209676 211019 D putative Na+/H+ antiporter 209676..211019 Vibrio cholerae M66-2 7781482 YP_002811828.1 CDS VCM66_A0190 NC_012580.1 211021 211863 R putative potassium channel protein complement(211021..211863) Vibrio cholerae M66-2 7781483 YP_002811829.1 CDS VCM66_A0191 NC_012580.1 211929 212477 R hypothetical protein complement(211929..212477) Vibrio cholerae M66-2 7781484 YP_002811830.1 CDS VCM66_A0192 NC_012580.1 212593 212970 R hypothetical protein complement(212593..212970) Vibrio cholerae M66-2 7781485 YP_002811831.1 CDS guaC NC_012580.1 213135 214178 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 213135..214178 Vibrio cholerae M66-2 7781486 YP_002811832.1 CDS VCM66_A0194 NC_012580.1 214502 215653 D putative site-specific DNA-methyltransferase 214502..215653 Vibrio cholerae M66-2 7781487 YP_002811833.1 CDS VCM66_A0195 NC_012580.1 215777 217693 D hypothetical protein 215777..217693 Vibrio cholerae M66-2 7781488 YP_002811834.1 CDS VCM66_A0196 NC_012580.1 217686 218810 D hypothetical protein 217686..218810 Vibrio cholerae M66-2 7781489 YP_002811835.1 CDS VCM66_A0197 NC_012580.1 218807 219685 D hypothetical protein 218807..219685 Vibrio cholerae M66-2 7781490 YP_002811836.1 CDS tnpA NC_012580.1 219753 220190 R IS1004 transposase complement(219753..220190) Vibrio cholerae M66-2 7781491 YP_002811837.1 CDS rhlE-2 NC_012580.1 220695 222050 R ATP-dependent RNA helicase RhlE complement(220695..222050) Vibrio cholerae M66-2 7781492 YP_002811838.1 CDS dcuB NC_012580.1 222240 223568 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(222240..223568) Vibrio cholerae M66-2 7781493 YP_002811839.1 CDS nadE NC_012580.1 223818 224648 R catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(223818..224648) Vibrio cholerae M66-2 7781494 YP_002811840.1 CDS VCM66_A0204 NC_012580.1 224751 225278 D catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP; nicotinic acid mononucleotide adenylyltransferase 224751..225278 Vibrio cholerae M66-2 7781495 YP_002811841.1 CDS VCM66_A0205 NC_012580.1 225229 225411 D hypothetical protein 225229..225411 Vibrio cholerae M66-2 7781496 YP_002811842.1 CDS VCM66_A0206 NC_012580.1 225518 227086 D putative response regulator 225518..227086 Vibrio cholerae M66-2 7781497 YP_002811843.1 CDS VCM66_A0207 NC_012580.1 227144 229090 R sensory box sensor histidine kinase complement(227144..229090) Vibrio cholerae M66-2 7781498 YP_002811844.1 CDS VCM66_A0208 NC_012580.1 229265 230314 D hypothetical protein 229265..230314 Vibrio cholerae M66-2 7781499 YP_002811845.1 CDS VCM66_A0209 NC_012580.1 230392 231981 R hypothetical protein complement(230392..231981) Vibrio cholerae M66-2 7781500 YP_002811846.1 CDS emrD NC_012580.1 232376 233620 R multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D complement(232376..233620) Vibrio cholerae M66-2 7781501 YP_002811847.1 CDS VCM66_A0211 NC_012580.1 233621 233779 R hypothetical protein complement(233621..233779) Vibrio cholerae M66-2 7781502 YP_002811848.1 CDS VCM66_A0212 NC_012580.1 233834 234100 D hypothetical protein 233834..234100 Vibrio cholerae M66-2 7781503 YP_002811849.1 CDS VCM66_A0213 NC_012580.1 234091 235170 R GGDEF family protein complement(234091..235170) Vibrio cholerae M66-2 7781504 YP_002811850.1 CDS VCM66_A0214 NC_012580.1 235291 236547 R thermolabile hemolysin complement(235291..236547) Vibrio cholerae M66-2 7781505 YP_002811851.1 CDS hlyA NC_012580.1 237517 239742 D hemolysin 237517..239742 Vibrio cholerae M66-2 7781506 YP_002811852.1 CDS hylB NC_012580.1 240041 241687 D hemolysin secretion protein HylB 240041..241687 Vibrio cholerae M66-2 7781507 YP_002811853.1 CDS hlyC NC_012580.1 241954 242973 D lactonizing lipase 241954..242973 Vibrio cholerae M66-2 7781508 YP_002811854.1 CDS VCM66_A0218 NC_012580.1 242983 243837 D acts as a molecular chaperone to fold and export lipase A; lipase chaperone 242983..243837 Vibrio cholerae M66-2 7781509 YP_002811855.1 CDS prtV NC_012580.1 243913 246669 R protease complement(243913..246669) Vibrio cholerae M66-2 7781510 YP_002811856.1 CDS VCM66_A0220 NC_012580.1 246754 247059 R hypothetical protein complement(246754..247059) Vibrio cholerae M66-2 7781511 YP_002811857.1 CDS VCM66_A0221 NC_012580.1 247613 248377 D hypothetical protein 247613..248377 Vibrio cholerae M66-2 7781512 YP_002811858.1 CDS VCM66_A0222 NC_012580.1 248537 248659 R hypothetical protein complement(248537..248659) Vibrio cholerae M66-2 7781513 YP_002811859.1 CDS vctP NC_012580.1 248693 249694 D vibriobactin and enterobactin ABC transporter, periplasmic vibriobactin/enterobactin-binding protein 248693..249694 Vibrio cholerae M66-2 7781514 YP_002811860.1 CDS vctD NC_012580.1 249747 250685 D vibriobactin and enterobactin ABC transporter, permease protein 249747..250685 Vibrio cholerae M66-2 7781515 YP_002811861.1 CDS vctG NC_012580.1 250675 251625 D vibriobactin and enterobactin ABC transporter, permease protein 250675..251625 Vibrio cholerae M66-2 7781516 YP_002811862.1 CDS vctC NC_012580.1 251628 252392 D vibriobactin and enterobactin ABC transporter, ATP-binding protein 251628..252392 Vibrio cholerae M66-2 7781517 YP_002811863.1 CDS VCM66_A0227 NC_012580.1 252438 253514 R AraC family transcriptional regulator complement(252438..253514) Vibrio cholerae M66-2 7781518 YP_002811864.1 CDS vctA NC_012580.1 253541 255520 D enterobactin receptor VctA 253541..255520 Vibrio cholerae M66-2 7781519 YP_002811865.1 CDS VCM66_A0229 NC_012580.1 255578 255898 D hypothetical protein 255578..255898 Vibrio cholerae M66-2 7781520 YP_002811866.1 CDS VCM66_A0230 NC_012580.1 255914 256030 D hypothetical protein 255914..256030 Vibrio cholerae M66-2 7781521 YP_002811867.1 CDS ackA-2 NC_012580.1 256168 257361 D AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 256168..257361 Vibrio cholerae M66-2 7781522 YP_002811868.1 CDS VCM66_A0232 NC_012580.1 257442 257738 D hypothetical protein 257442..257738 Vibrio cholerae M66-2 7781523 YP_002811869.1 CDS VCM66_A0233 NC_012580.1 257856 258425 R hypothetical protein complement(257856..258425) Vibrio cholerae M66-2 7781524 YP_002811870.1 CDS VCM66_A0234 NC_012580.1 258670 260319 D sensor histidine kinase 258670..260319 Vibrio cholerae M66-2 7781525 YP_002811871.1 CDS VCM66_A0235 NC_012580.1 260300 260974 D transcriptional regulator 260300..260974 Vibrio cholerae M66-2 7781526 YP_002811872.1 CDS VCM66_A0236 NC_012580.1 260977 261606 R hypothetical protein complement(260977..261606) Vibrio cholerae M66-2 7781527 YP_002811873.1 CDS VCM66_A0237 NC_012580.1 261566 262450 R L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; putative L-xylulose 5-phosphate 3-epimerase complement(261566..262450) Vibrio cholerae M66-2 7781528 YP_002811874.1 CDS ulaD NC_012580.1 262462 263109 R catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase complement(262462..263109) Vibrio cholerae M66-2 7781529 YP_002811875.1 CDS VCM66_A0239 NC_012580.1 263115 263936 R hypothetical protein complement(263115..263936) Vibrio cholerae M66-2 7781530 YP_002811876.1 CDS araD NC_012580.1 263942 264634 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(263942..264634) Vibrio cholerae M66-2 7781531 YP_002811877.1 CDS VCM66_A0241 NC_012580.1 264643 265149 R PTS system, IIA component complement(264643..265149) Vibrio cholerae M66-2 7781532 YP_002811878.1 CDS sgaT NC_012580.1 265247 267007 R PTS system ascorbate-specific transporter subunits IICB complement(265247..267007) Vibrio cholerae M66-2 7781533 YP_002811879.1 CDS VCM66_A0243 NC_012580.1 267373 268128 D negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 267373..268128 Vibrio cholerae M66-2 7781534 YP_002811880.1 CDS VCM66_A0244 NC_012580.1 268255 269322 D putative L-ascorbate 6-phosphate lactonase 268255..269322 Vibrio cholerae M66-2 7781535 YP_002811881.1 CDS VCM66_A0245 NC_012580.1 269422 269955 R putative cytochrome b561 complement(269422..269955) Vibrio cholerae M66-2 7781536 YP_002811882.1 CDS amy1 NC_012580.1 270128 271528 R alpha-amylase complement(270128..271528) Vibrio cholerae M66-2 7781537 YP_002811883.1 CDS VCM66_A0247 NC_012580.1 271668 271784 D hypothetical protein 271668..271784 Vibrio cholerae M66-2 7781538 YP_002811884.1 CDS VCM66_A0248 NC_012580.1 271744 271854 D hypothetical protein 271744..271854 Vibrio cholerae M66-2 7781539 YP_002811885.1 CDS VCM66_A0249 NC_012580.1 271861 272559 D antibiotic acetyltransferase 271861..272559 Vibrio cholerae M66-2 7781540 YP_002811886.1 CDS VCM66_A0250 NC_012580.1 272678 272944 R hypothetical protein complement(272678..272944) Vibrio cholerae M66-2 7781541 YP_002811887.1 CDS VCM66_A0251 NC_012580.1 273116 275347 R hypothetical protein complement(273116..275347) Vibrio cholerae M66-2 7781542 YP_002811888.1 CDS VCM66_A0252 NC_012580.1 275436 276266 R hypothetical protein complement(275436..276266) Vibrio cholerae M66-2 7781543 YP_002811889.1 CDS VCM66_A0253 NC_012580.1 276263 276934 R transcriptional regulator complement(276263..276934) Vibrio cholerae M66-2 7781544 YP_002811890.1 CDS VCM66_A0254 NC_012580.1 276910 278364 R sensor histidine kinase complement(276910..278364) Vibrio cholerae M66-2 7781545 YP_002811891.1 CDS VCM66_A0255 NC_012580.1 278467 278979 R hypothetical protein complement(278467..278979) Vibrio cholerae M66-2 7781546 YP_002811892.1 CDS VCM66_A0256 NC_012580.1 279022 279150 R hypothetical protein complement(279022..279150) Vibrio cholerae M66-2 7781547 YP_002811893.1 CDS VCM66_A0257 NC_012580.1 279174 279683 R hypothetical protein complement(279174..279683) Vibrio cholerae M66-2 7781548 YP_002811894.1 CDS VCM66_A0258 NC_012580.1 279793 280203 R hypothetical protein complement(279793..280203) Vibrio cholerae M66-2 7781549 YP_002811895.1 CDS VCM66_A0259 NC_012580.1 280309 280851 R putative acetyltransferase complement(280309..280851) Vibrio cholerae M66-2 7781550 YP_002811896.1 CDS VCM66_A0260 NC_012580.1 280862 282040 R putative transcriptional regulator complement(280862..282040) Vibrio cholerae M66-2 7781551 YP_002811897.1 CDS VCM66_A0261 NC_012580.1 282224 282604 D hypothetical protein 282224..282604 Vibrio cholerae M66-2 7781552 YP_002811898.1 CDS VCM66_A0262 NC_012580.1 282664 283437 R AraC family transcriptional regulator complement(282664..283437) Vibrio cholerae M66-2 7781553 YP_002811899.1 CDS emrD-3 NC_012580.1 283539 284678 D multidrug resistance protein D 283539..284678 Vibrio cholerae M66-2 7781554 YP_002811900.1 CDS VCM66_A0264 NC_012580.1 284961 286892 D methyl-accepting chemotaxis protein 284961..286892 Vibrio cholerae M66-2 7781555 YP_002811901.1 CDS VCM66_A0265 NC_012580.1 286908 288581 D decarboxylase, group II 286908..288581 Vibrio cholerae M66-2 7781556 YP_002811902.1 CDS dacA-2 NC_012580.1 288746 289915 D D-alanyl-D-alanine carboxypeptidase 288746..289915 Vibrio cholerae M66-2 7781557 YP_002811903.1 CDS VCM66_A0267 NC_012580.1 290093 290440 D hypothetical protein 290093..290440 Vibrio cholerae M66-2 7781558 YP_002811904.1 CDS VCM66_A0268 NC_012580.1 290535 290969 R hypothetical protein complement(290535..290969) Vibrio cholerae M66-2 7781559 YP_002811905.1 CDS VCM66_A0269 NC_012580.1 291024 291158 D hypothetical protein 291024..291158 Vibrio cholerae M66-2 7781560 YP_002811906.1 CDS cah NC_012580.1 291186 291905 D carbonic anhydrase 291186..291905 Vibrio cholerae M66-2 7781561 YP_002811907.1 CDS VCM66_A0272 NC_012580.1 292407 293279 R ISVch4 transposase, OrfA complement(292407..293279) Vibrio cholerae M66-2 7781562 YP_002811908.1 CDS VCM66_A0273 NC_012580.1 293276 293620 R ISVch4 transposase, OrfB complement(293276..293620) Vibrio cholerae M66-2 7781563 YP_002811909.1 CDS gcvP NC_012580.1 294070 296934 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(294070..296934) Vibrio cholerae M66-2 7781564 YP_002811910.1 CDS gcvH NC_012580.1 297078 297458 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(297078..297458) Vibrio cholerae M66-2 7781565 YP_002811911.1 CDS glyA-2 NC_012580.1 297495 298802 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(297495..298802) Vibrio cholerae M66-2 7781566 YP_002811912.1 CDS VCM66_A0278 NC_012580.1 299190 299813 D transcriptional regulator, HTH_3 family 299190..299813 Vibrio cholerae M66-2 7781567 YP_002811913.1 CDS gcvT NC_012580.1 300057 301187 D glycine cleavage system T protein 300057..301187 Vibrio cholerae M66-2 7781568 YP_002811914.1 CDS VCM66_A0280 NC_012580.1 301654 302811 D putative integrase 301654..302811 Vibrio cholerae M66-2 7781569 YP_002811915.1 CDS VCM66_A0281 NC_012580.1 302857 303837 D ISVch5 transposase 302857..303837 Vibrio cholerae M66-2 7781570 YP_002811916.1 CDS VCM66_A0282 NC_012580.1 304113 305348 D hypothetical protein 304113..305348 Vibrio cholerae M66-2 7781571 YP_002811917.1 CDS VCM66_A0283 NC_012580.1 305869 306399 D hypothetical protein 305869..306399 Vibrio cholerae M66-2 7781572 YP_002811918.1 CDS VCM66_A0284 NC_012580.1 306399 307070 D hypothetical protein 306399..307070 Vibrio cholerae M66-2 7781573 YP_002811919.1 CDS VCM66_A0285 NC_012580.1 307072 307422 D hypothetical protein 307072..307422 Vibrio cholerae M66-2 7781574 YP_002811920.1 CDS thrS NC_012580.1 307691 309619 D catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 307691..309619 Vibrio cholerae M66-2 7781575 YP_002811921.1 CDS infC NC_012580.1 309785 310174 D initiation factor IF3 309785..310174 Vibrio cholerae M66-2 7781576 YP_002811922.1 CDS rpmI NC_012580.1 310278 310472 D 50S ribosomal protein L35 310278..310472 Vibrio cholerae M66-2 7781577 YP_002811923.1 CDS rplT NC_012580.1 310514 310867 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 310514..310867 Vibrio cholerae M66-2 7781578 YP_002811924.1 CDS VCM66_A0290 NC_012580.1 310949 311911 R site-specific recombinase IntI4 complement(310949..311911) Vibrio cholerae M66-2 7781579 YP_002811925.1 CDS VCM66_A0291 NC_012580.1 312157 312549 D hypothetical protein 312157..312549 Vibrio cholerae M66-2 7781580 YP_002811926.1 CDS VCM66_A0292 NC_012580.1 312669 313064 D hypothetical protein 312669..313064 Vibrio cholerae M66-2 7781581 YP_002811927.1 CDS VCM66_A0293 NC_012580.1 313256 313366 R hypothetical protein complement(313256..313366) Vibrio cholerae M66-2 7781582 YP_002811928.1 CDS VCM66_A0294 NC_012580.1 313423 313518 D hypothetical protein 313423..313518 Vibrio cholerae M66-2 7781583 YP_002811929.1 CDS VCM66_A0295 NC_012580.1 313730 314089 D Glyoxalase/bleomycin resistance protein 313730..314089 Vibrio cholerae M66-2 7781584 YP_002811930.1 CDS VCM66_A0296 NC_012580.1 314221 314709 D OsmC-like protein 314221..314709 Vibrio cholerae M66-2 7781585 YP_002811931.1 CDS VCM66_A0297 NC_012580.1 314828 314989 D hypothetical protein 314828..314989 Vibrio cholerae M66-2 7781586 YP_002811932.1 CDS VCM66_A0300 NC_012580.1 315406 315654 D hypothetical protein 315406..315654 Vibrio cholerae M66-2 7781587 YP_002811933.1 CDS VCM66_A0301 NC_012580.1 315851 316969 D hypothetical protein 315851..316969 Vibrio cholerae M66-2 7781588 YP_002811934.1 CDS VCM66_A0302 NC_012580.1 317111 317587 D GCN5-related N-acetyltransferase 317111..317587 Vibrio cholerae M66-2 7781589 YP_002811935.1 CDS VCM66_A0303 NC_012580.1 317764 317898 R hypothetical protein complement(317764..317898) Vibrio cholerae M66-2 7781590 YP_002811936.1 CDS VCM66_A0304 NC_012580.1 317883 318062 D hypothetical protein 317883..318062 Vibrio cholerae M66-2 7781591 YP_002811937.1 CDS VCM66_A0305 NC_012580.1 318250 318771 D GCN5-related N-acetyltransferase 318250..318771 Vibrio cholerae M66-2 7781592 YP_002811938.1 CDS VCM66_A0306 NC_012580.1 318907 319422 D Lipocalin-like protein 318907..319422 Vibrio cholerae M66-2 7781593 YP_002811939.1 CDS VCM66_A0307 NC_012580.1 319559 320101 D hypothetical protein 319559..320101 Vibrio cholerae M66-2 7781594 YP_002811940.1 CDS VCM66_A0308 NC_012580.1 320220 320381 D hypothetical protein 320220..320381 Vibrio cholerae M66-2 7781595 YP_002811941.1 CDS VCM66_A0311 NC_012580.1 320893 321045 D hypothetical protein 320893..321045 Vibrio cholerae M66-2 7781596 YP_002811942.1 CDS VCM66_A0312 NC_012580.1 321245 321523 R plasmid stabilization system protein complement(321245..321523) Vibrio cholerae M66-2 7781597 YP_002811943.1 CDS VCM66_A0313 NC_012580.1 321520 321840 R relB protein complement(321520..321840) Vibrio cholerae M66-2 7781598 YP_002811944.1 CDS VCM66_A0314 NC_012580.1 321980 322279 R putative plasmid stabilization element ParE complement(321980..322279) Vibrio cholerae M66-2 7781599 YP_002811945.1 CDS VCM66_A0315 NC_012580.1 322266 322589 R hypothetical protein complement(322266..322589) Vibrio cholerae M66-2 7781600 YP_002811946.1 CDS VCM66_A0318 NC_012580.1 324264 324692 D GCN5-related N-acetyltransferase 324264..324692 Vibrio cholerae M66-2 7781601 YP_002811947.1 CDS VCM66_A0319 NC_012580.1 325280 325762 D GCN5-related N-acetyltransferase 325280..325762 Vibrio cholerae M66-2 7781602 YP_002811948.1 CDS VCM66_A0320 NC_012580.1 326564 326839 D hypothetical protein 326564..326839 Vibrio cholerae M66-2 7781603 YP_002811949.1 CDS VCM66_A0321 NC_012580.1 326833 327354 D hypothetical protein 326833..327354 Vibrio cholerae M66-2 7781604 YP_002811950.1 CDS VCM66_A0322 NC_012580.1 327493 328329 D hypothetical protein 327493..328329 Vibrio cholerae M66-2 7781605 YP_002811951.1 CDS VCM66_A0323 NC_012580.1 328494 329132 D Metal-dependent phosphohydrolase with HD region, subdomain 328494..329132 Vibrio cholerae M66-2 7781606 YP_002811952.1 CDS VCM66_A0324 NC_012580.1 329403 329624 D hypothetical protein 329403..329624 Vibrio cholerae M66-2 7781607 YP_002811953.1 CDS VCM66_A0325 NC_012580.1 329944 330264 D hypothetical protein 329944..330264 Vibrio cholerae M66-2 7781608 YP_002811954.1 CDS VCM66_A0326 NC_012580.1 330261 330794 D GCN5-related N-acetyltransferase 330261..330794 Vibrio cholerae M66-2 7781609 YP_002811955.1 CDS VCM66_A0327 NC_012580.1 330987 331310 D hypothetical protein 330987..331310 Vibrio cholerae M66-2 7781610 YP_002811956.1 CDS VCM66_A0328 NC_012580.1 331562 331687 D hypothetical protein 331562..331687 Vibrio cholerae M66-2 7781611 YP_002811957.1 CDS VCM66_A0328a NC_012580.1 331711 331935 D hypothetical protein 331711..331935 Vibrio cholerae M66-2 7781612 YP_002811958.1 CDS VCM66_A0329 NC_012580.1 332186 332458 R hypothetical protein complement(332186..332458) Vibrio cholerae M66-2 7781613 YP_002811959.1 CDS VCM66_A0330 NC_012580.1 332628 333062 D hypothetical protein 332628..333062 Vibrio cholerae M66-2 7781614 YP_002811960.1 CDS VCM66_A0331 NC_012580.1 333195 333710 D hypothetical protein 333195..333710 Vibrio cholerae M66-2 7781615 YP_002811961.1 CDS VCM66_A0332 NC_012580.1 333851 334288 D NUDIX hydrolase 333851..334288 Vibrio cholerae M66-2 7781616 YP_002811962.1 CDS VCM66_A0333 NC_012580.1 334449 334796 D hypothetical protein 334449..334796 Vibrio cholerae M66-2 7781617 YP_002811963.1 CDS VCM66_A0334 NC_012580.1 334937 336502 D hypothetical protein 334937..336502 Vibrio cholerae M66-2 7781618 YP_002811964.1 CDS VCM66_A0335 NC_012580.1 336638 337198 D hypothetical protein 336638..337198 Vibrio cholerae M66-2 7781619 YP_002811965.1 CDS VCM66_A0336 NC_012580.1 337348 338022 D hypothetical protein 337348..338022 Vibrio cholerae M66-2 7781620 YP_002811966.1 CDS VCM66_A0337 NC_012580.1 338253 338501 D hypothetical protein 338253..338501 Vibrio cholerae M66-2 7781621 YP_002811967.1 CDS VCM66_A0338 NC_012580.1 338716 339468 D Short-chain dehydrogenase/reductase SDR 338716..339468 Vibrio cholerae M66-2 7781622 YP_002811968.1 CDS VCM66_A0339 NC_012580.1 339770 339952 D hypothetical protein 339770..339952 Vibrio cholerae M66-2 7781623 YP_002811969.1 CDS VCM66_A0340 NC_012580.1 340130 340534 D hypothetical protein 340130..340534 Vibrio cholerae M66-2 7781624 YP_002811970.1 CDS VCM66_A0341 NC_012580.1 340830 341012 D hypothetical protein 340830..341012 Vibrio cholerae M66-2 7781625 YP_002811971.1 CDS VCM66_A0342 NC_012580.1 341250 341366 R hypothetical protein complement(341250..341366) Vibrio cholerae M66-2 7781626 YP_002811972.1 CDS VCM66_A0343 NC_012580.1 341366 341548 D hypothetical protein 341366..341548 Vibrio cholerae M66-2 7781627 YP_002811973.1 CDS VCM66_A0344 NC_012580.1 341743 342420 D HNH endonuclease 341743..342420 Vibrio cholerae M66-2 7781628 YP_002811974.1 CDS VCM66_A0345 NC_012580.1 342582 343790 D deoxyguanosinetriphosphate triphosphohydrolase-related protein 342582..343790 Vibrio cholerae M66-2 7781629 YP_002811975.1 CDS VCM66_A0346 NC_012580.1 343952 344656 D HNH endonuclease 343952..344656 Vibrio cholerae M66-2 7781630 YP_002811976.1 CDS VCM66_A0347 NC_012580.1 344787 345152 D hypothetical protein 344787..345152 Vibrio cholerae M66-2 7781631 YP_002811977.1 CDS VCM66_A0348 NC_012580.1 345306 345641 R Plasmid stabilization system protein complement(345306..345641) Vibrio cholerae M66-2 7781632 YP_002811978.1 CDS VCM66_A0349 NC_012580.1 345642 345884 R Prevent-host-death protein complement(345642..345884) Vibrio cholerae M66-2 7781633 YP_002811979.1 CDS VCM66_A0350 NC_012580.1 346128 346514 D NUDIX hydrolase 346128..346514 Vibrio cholerae M66-2 7781634 YP_002811980.1 CDS VCM66_A0351 NC_012580.1 346633 346914 D hypothetical protein 346633..346914 Vibrio cholerae M66-2 7781635 YP_002811981.1 CDS VCM66_A0352 NC_012580.1 346890 347021 R hypothetical protein complement(346890..347021) Vibrio cholerae M66-2 7781636 YP_002811982.1 CDS VCM66_A0355 NC_012580.1 347172 347708 D GCN5-related N-acetyltransferase 347172..347708 Vibrio cholerae M66-2 7781637 YP_002811983.1 CDS VCM66_A0356 NC_012580.1 347845 348360 D Lipocalin-like protein 347845..348360 Vibrio cholerae M66-2 7781638 YP_002811984.1 CDS VCM66_A0357 NC_012580.1 348510 349007 R GCN5-related N-acetyltransferase complement(348510..349007) Vibrio cholerae M66-2 7781639 YP_002811985.1 CDS VCM66_A0358 NC_012580.1 349004 349276 R hypothetical protein complement(349004..349276) Vibrio cholerae M66-2 7781640 YP_002811986.1 CDS VCM66_A0359 NC_012580.1 349502 349666 R hypothetical protein complement(349502..349666) Vibrio cholerae M66-2 7781641 YP_002811987.1 CDS VCM66_A0360 NC_012580.1 349781 349891 R hypothetical protein complement(349781..349891) Vibrio cholerae M66-2 7781642 YP_002811988.1 CDS VCM66_A0361 NC_012580.1 350038 350490 D hypothetical protein 350038..350490 Vibrio cholerae M66-2 7781643 YP_002811989.1 CDS VCM66_A0362 NC_012580.1 350638 350934 R plasmid stabilization system protein complement(350638..350934) Vibrio cholerae M66-2 7781644 YP_002811990.1 CDS VCM66_A0363 NC_012580.1 350900 351178 R DNA-damage-inducible protein J complement(350900..351178) Vibrio cholerae M66-2 7781645 YP_002811991.1 CDS VCM66_A0364 NC_012580.1 351428 351685 D antitoxin of toxin-antitoxin stability system 351428..351685 Vibrio cholerae M66-2 7781646 YP_002811992.1 CDS VCM66_A0365 NC_012580.1 351673 351975 D plasmid stabilization system protein 351673..351975 Vibrio cholerae M66-2 7781647 YP_002811993.1 CDS VCM66_A0365a NC_012580.1 352115 352240 D hypothetical protein 352115..352240 Vibrio cholerae M66-2 7781648 YP_002811994.1 CDS VCM66_A0366 NC_012580.1 352264 352488 D hypothetical protein 352264..352488 Vibrio cholerae M66-2 7781649 YP_002811995.1 CDS VCM66_A0368 NC_012580.1 353273 353545 R hypothetical protein complement(353273..353545) Vibrio cholerae M66-2 7781650 YP_002811996.1 CDS VCM66_A0369 NC_012580.1 353710 354714 D microcin immunity protein MccF 353710..354714 Vibrio cholerae M66-2 7781651 YP_002811997.1 CDS VCM66_A0370 NC_012580.1 354906 355163 D hypothetical protein 354906..355163 Vibrio cholerae M66-2 7781652 YP_002811998.1 CDS VCM66_A0371 NC_012580.1 355870 356223 D putative killer protein 355870..356223 Vibrio cholerae M66-2 7781653 YP_002811999.1 CDS VCM66_A0372 NC_012580.1 356234 356551 D putative antidote protein 356234..356551 Vibrio cholerae M66-2 7781654 YP_002812000.1 CDS VCM66_A0373 NC_012580.1 356731 357054 D hypothetical protein 356731..357054 Vibrio cholerae M66-2 7781655 YP_002812001.1 CDS VCM66_A0374 NC_012580.1 357097 357198 R hypothetical protein complement(357097..357198) Vibrio cholerae M66-2 7781656 YP_002812002.1 CDS VCM66_A0375 NC_012580.1 357369 357512 D hypothetical protein 357369..357512 Vibrio cholerae M66-2 7781657 YP_002812003.1 CDS VCM66_A0376 NC_012580.1 357791 358189 D Glyoxalase/bleomycin resistance protein 357791..358189 Vibrio cholerae M66-2 7781658 YP_002812004.1 CDS VCM66_A0377 NC_012580.1 358384 358635 D hypothetical protein 358384..358635 Vibrio cholerae M66-2 7781659 YP_002812005.1 CDS VCM66_A0378 NC_012580.1 358809 359162 D hypothetical protein 358809..359162 Vibrio cholerae M66-2 7781660 YP_002812006.1 CDS VCM66_A0379 NC_012580.1 359374 359616 D hypothetical protein 359374..359616 Vibrio cholerae M66-2 7781661 YP_002812007.1 CDS VCM66_A0380 NC_012580.1 359823 360146 D hypothetical protein 359823..360146 Vibrio cholerae M66-2 7781662 YP_002812008.1 CDS VCM66_A0381 NC_012580.1 360947 361435 D OsmC-like protein 360947..361435 Vibrio cholerae M66-2 7781663 YP_002812009.1 CDS VCM66_A0382 NC_012580.1 361620 362225 D hypothetical protein 361620..362225 Vibrio cholerae M66-2 7781664 YP_002812010.1 CDS VCM66_A0383 NC_012580.1 362410 362676 D hypothetical protein 362410..362676 Vibrio cholerae M66-2 7781665 YP_002812011.1 CDS VCM66_A0384 NC_012580.1 362663 362908 D hypothetical protein 362663..362908 Vibrio cholerae M66-2 7781666 YP_002812012.1 CDS VCM66_A0385 NC_012580.1 362992 363798 D hypothetical protein 362992..363798 Vibrio cholerae M66-2 7781667 YP_002812013.1 CDS VCM66_A0386 NC_012580.1 364007 364108 R hypothetical protein complement(364007..364108) Vibrio cholerae M66-2 7781668 YP_002812014.1 CDS VCM66_A0387 NC_012580.1 364090 364272 D hypothetical protein 364090..364272 Vibrio cholerae M66-2 7781669 YP_002812015.1 CDS VCM66_A0388 NC_012580.1 364469 364894 D GCN5-related N-acetyltransferase 364469..364894 Vibrio cholerae M66-2 7781670 YP_002812016.1 CDS VCM66_A0389 NC_012580.1 365034 365624 D hypothetical protein 365034..365624 Vibrio cholerae M66-2 7781671 YP_002812017.1 CDS VCM66_A0390 NC_012580.1 365778 366137 D Glyoxalase/bleomycin resistance protein 365778..366137 Vibrio cholerae M66-2 7781672 YP_002812018.1 CDS VCM66_A0391 NC_012580.1 366284 366937 D hypothetical protein 366284..366937 Vibrio cholerae M66-2 7781673 YP_002812019.1 CDS VCM66_A0393 NC_012580.1 367746 368042 D Stress responsive alpha-beta barrel 367746..368042 Vibrio cholerae M66-2 7781675 YP_002812020.1 CDS VCM66_A0394 NC_012580.1 368196 368588 D hypothetical protein 368196..368588 Vibrio cholerae M66-2 7781676 YP_002812021.1 CDS VCM66_A0396 NC_012580.1 369634 370506 R ISVch4 transposase, OrfA complement(369634..370506) Vibrio cholerae M66-2 7781678 YP_002812022.1 CDS VCM66_A0397 NC_012580.1 370503 370847 R ISVch4 transposase, OrfB complement(370503..370847) Vibrio cholerae M66-2 7781679 YP_002812023.1 CDS VCM66_A0399 NC_012580.1 371199 372236 D hypothetical protein 371199..372236 Vibrio cholerae M66-2 7781681 YP_002812024.1 CDS VCM66_A0400 NC_012580.1 372908 373261 D putative killer protein 372908..373261 Vibrio cholerae M66-2 7781682 YP_002812025.1 CDS VCM66_A0401 NC_012580.1 373272 373589 D putative antidote protein 373272..373589 Vibrio cholerae M66-2 7781683 YP_002812026.1 CDS VCM66_A0402 NC_012580.1 373724 374200 D GCN5-related N-acetyltransferase 373724..374200 Vibrio cholerae M66-2 7781684 YP_002812027.1 CDS VCM66_A0403 NC_012580.1 374337 374852 D Lipocalin-like protein 374337..374852 Vibrio cholerae M66-2 7781685 YP_002812028.1 CDS VCM66_A0404 NC_012580.1 374988 375278 R relE protein complement(374988..375278) Vibrio cholerae M66-2 7781686 YP_002812029.1 CDS VCM66_A0405 NC_012580.1 375268 375516 R antitoxin of toxin-antitoxin stability system, StbD family complement(375268..375516) Vibrio cholerae M66-2 7781687 YP_002812030.1 CDS VCM66_A0406 NC_012580.1 375781 375972 D hypothetical protein 375781..375972 Vibrio cholerae M66-2 7781688 YP_002812031.1 CDS VCM66_A0407 NC_012580.1 376048 376740 D DNA methylase N-4/N-6 376048..376740 Vibrio cholerae M66-2 7781689 YP_002812032.1 CDS VCM66_A0408 NC_012580.1 377012 377437 D hypothetical protein 377012..377437 Vibrio cholerae M66-2 7781690 YP_002812033.1 CDS VCM66_A0409 NC_012580.1 377615 378040 D hypothetical protein 377615..378040 Vibrio cholerae M66-2 7781691 YP_002812034.1 CDS VCM66_A0410 NC_012580.1 378191 378721 D hypothetical protein 378191..378721 Vibrio cholerae M66-2 7781692 YP_002812035.1 CDS VCM66_A0411 NC_012580.1 378859 379359 D hypothetical protein 378859..379359 Vibrio cholerae M66-2 7781693 YP_002812036.1 CDS VCM66_A0412 NC_012580.1 379485 379913 D hypothetical protein 379485..379913 Vibrio cholerae M66-2 7781694 YP_002812037.1 CDS VCM66_A0413 NC_012580.1 380013 380477 R hypothetical protein complement(380013..380477) Vibrio cholerae M66-2 7781695 YP_002812038.1 CDS VCM66_A0414 NC_012580.1 380860 381846 R periplasmic sulfate binding protein SBP complement(380860..381846) Vibrio cholerae M66-2 7781696 YP_002812039.1 CDS VCM66_A0415 NC_012580.1 382079 382675 D ThiJ/PfpI 382079..382675 Vibrio cholerae M66-2 7781697 YP_002812040.1 CDS VCM66_A0416 NC_012580.1 382966 383100 R hypothetical protein complement(382966..383100) Vibrio cholerae M66-2 7781698 YP_002812041.1 CDS VCM66_A0417 NC_012580.1 383472 384086 D hypothetical protein 383472..384086 Vibrio cholerae M66-2 7781699 YP_002812042.1 CDS VCM66_A0418 NC_012580.1 384233 385090 D hypothetical protein 384233..385090 Vibrio cholerae M66-2 7781700 YP_002812043.1 CDS VCM66_A0419 NC_012580.1 385237 385797 D hypothetical protein 385237..385797 Vibrio cholerae M66-2 7781701 YP_002812044.1 CDS VCM66_A0420 NC_012580.1 385940 386287 D hypothetical protein 385940..386287 Vibrio cholerae M66-2 7781702 YP_002812045.1 CDS VCM66_A0421 NC_012580.1 386418 386543 D hypothetical protein 386418..386543 Vibrio cholerae M66-2 7781703 YP_002812046.1 CDS VCM66_A0422 NC_012580.1 386679 386783 R hypothetical protein complement(386679..386783) Vibrio cholerae M66-2 7781704 YP_002812047.1 CDS VCM66_A0423 NC_012580.1 388056 388454 D Glyoxalase/bleomycin resistance protein 388056..388454 Vibrio cholerae M66-2 7781705 YP_002812048.1 CDS VCM66_A0424 NC_012580.1 388656 388898 D hypothetical protein 388656..388898 Vibrio cholerae M66-2 7781706 YP_002812049.1 CDS VCM66_A0425 NC_012580.1 389042 389446 D hypothetical protein 389042..389446 Vibrio cholerae M66-2 7781707 YP_002812050.1 CDS VCM66_A0426 NC_012580.1 389566 389847 D hypothetical protein 389566..389847 Vibrio cholerae M66-2 7781708 YP_002812051.1 CDS VCM66_A0427 NC_012580.1 389823 389954 R hypothetical protein complement(389823..389954) Vibrio cholerae M66-2 7781709 YP_002812052.1 CDS VCM66_A0429 NC_012580.1 390332 390463 R hypothetical protein complement(390332..390463) Vibrio cholerae M66-2 7781711 YP_002812053.1 CDS VCM66_A0430 NC_012580.1 390643 390975 D hypothetical protein 390643..390975 Vibrio cholerae M66-2 7781712 YP_002812054.1 CDS VCM66_A0431 NC_012580.1 390962 391276 D virulence gene repressor RsaL 390962..391276 Vibrio cholerae M66-2 7781713 YP_002812055.1 CDS VCM66_A0432 NC_012580.1 391413 391847 D GCN5-related N-acetyltransferase 391413..391847 Vibrio cholerae M66-2 7781714 YP_002812056.1 CDS VCM66_A0433 NC_012580.1 392015 392170 D hypothetical protein 392015..392170 Vibrio cholerae M66-2 7781715 YP_002812057.1 CDS VCM66_A0434 NC_012580.1 392295 393275 R ISVch5 transposase complement(392295..393275) Vibrio cholerae M66-2 7781716 YP_002812058.1 CDS VCM66_A0435 NC_012580.1 393298 393615 D hypothetical protein 393298..393615 Vibrio cholerae M66-2 7781717 YP_002812059.1 CDS VCM66_A0436 NC_012580.1 393786 394478 D GCN5-related N-acetyltransferase 393786..394478 Vibrio cholerae M66-2 7781718 YP_002812060.1 CDS VCM66_A0437 NC_012580.1 394478 394879 D doc protein 394478..394879 Vibrio cholerae M66-2 7781719 YP_002812061.1 CDS VCM66_A0438 NC_012580.1 395067 395480 D Glyoxalase/bleomycin resistance protein 395067..395480 Vibrio cholerae M66-2 7781720 YP_002812062.1 CDS VCM66_A0439 NC_012580.1 395673 395945 D antitoxin of toxin-antitoxin stability system 395673..395945 Vibrio cholerae M66-2 7781721 YP_002812063.1 CDS VCM66_A0440 NC_012580.1 395932 396222 D Cytotoxic translational repressor of toxin-antitoxin stability system 395932..396222 Vibrio cholerae M66-2 7781722 YP_002812064.1 CDS VCM66_A0441 NC_012580.1 396350 396805 D GCN5-related N-acetyltransferase 396350..396805 Vibrio cholerae M66-2 7781723 YP_002812065.1 CDS VCM66_A0442 NC_012580.1 397127 397279 D hypothetical protein 397127..397279 Vibrio cholerae M66-2 7781724 YP_002812066.1 CDS VCM66_A0443 NC_012580.1 397481 397978 R GCN5-related N-acetyltransferase complement(397481..397978) Vibrio cholerae M66-2 7781725 YP_002812067.1 CDS VCM66_A0444 NC_012580.1 397975 398247 R hypothetical protein complement(397975..398247) Vibrio cholerae M66-2 7781726 YP_002812068.1 CDS VCM66_A0445 NC_012580.1 398478 399146 D hypothetical protein 398478..399146 Vibrio cholerae M66-2 7781727 YP_002812069.1 CDS VCM66_A0446 NC_012580.1 399298 399585 D hypothetical protein 399298..399585 Vibrio cholerae M66-2 7781728 YP_002812070.1 CDS VCM66_A0447 NC_012580.1 399726 400097 D mazG-related protein 399726..400097 Vibrio cholerae M66-2 7781729 YP_002812071.1 CDS VCM66_A0448 NC_012580.1 400269 400589 D hypothetical protein 400269..400589 Vibrio cholerae M66-2 7781730 YP_002812072.1 CDS VCM66_A0449 NC_012580.1 400586 401119 D GCN5-related N-acetyltransferase 400586..401119 Vibrio cholerae M66-2 7781731 YP_002812073.1 CDS VCM66_A0450 NC_012580.1 401321 401578 D antitoxin of toxin-antitoxin stability system 401321..401578 Vibrio cholerae M66-2 7781732 YP_002812074.1 CDS VCM66_A0451 NC_012580.1 401566 401868 D Plasmid stabilization system protein 401566..401868 Vibrio cholerae M66-2 7781733 YP_002812075.1 CDS VCM66_A0453 NC_012580.1 402350 402787 D IS1004 transposase 402350..402787 Vibrio cholerae M66-2 7781735 YP_002812076.1 CDS VCM66_A0455 NC_012580.1 403244 404116 D hypothetical protein 403244..404116 Vibrio cholerae M66-2 7781737 YP_002812077.1 CDS VCM66_A0456 NC_012580.1 404248 404865 D putative glutathione S-transferase 404248..404865 Vibrio cholerae M66-2 7781738 YP_002812078.1 CDS VCM66_A0457 NC_012580.1 405051 405326 D hypothetical protein 405051..405326 Vibrio cholerae M66-2 7781739 YP_002812079.1 CDS VCM66_A0458 NC_012580.1 405320 405841 D hypothetical protein 405320..405841 Vibrio cholerae M66-2 7781740 YP_002812080.1 CDS VCM66_A0459 NC_012580.1 405973 406137 R hypothetical protein complement(405973..406137) Vibrio cholerae M66-2 7781741 YP_002812081.1 CDS VCM66_A0460 NC_012580.1 406134 406235 R hypothetical protein complement(406134..406235) Vibrio cholerae M66-2 7781742 YP_002812082.1 CDS VCM66_A0461 NC_012580.1 406516 406911 D hypothetical protein 406516..406911 Vibrio cholerae M66-2 7781743 YP_002812083.1 CDS VCM66_A0462 NC_012580.1 407050 407328 R plasmid stabilization system protein complement(407050..407328) Vibrio cholerae M66-2 7781744 YP_002812084.1 CDS VCM66_A0463 NC_012580.1 407325 407645 R relB protein complement(407325..407645) Vibrio cholerae M66-2 7781745 YP_002812085.1 CDS VCM66_A0464 NC_012580.1 407797 408318 D GCN5-related N-acetyltransferase 407797..408318 Vibrio cholerae M66-2 7781746 YP_002812086.1 CDS VCM66_A0465 NC_012580.1 408502 408915 D Glyoxalase/bleomycin resistance protein 408502..408915 Vibrio cholerae M66-2 7781747 YP_002812087.1 CDS orfA NC_012580.1 409434 409778 D ISVch4 transposase, OrfA 409434..409778 Vibrio cholerae M66-2 7781748 YP_002812088.1 CDS orfB NC_012580.1 409775 410647 D ISVch4 transposase, OrfB 409775..410647 Vibrio cholerae M66-2 7781749 YP_002812089.1 CDS VCM66_A0468 NC_012580.1 410685 410804 R hypothetical protein complement(410685..410804) Vibrio cholerae M66-2 7781750 YP_002812090.1 CDS VCM66_A0469 NC_012580.1 410937 413843 D hypothetical protein 410937..413843 Vibrio cholerae M66-2 7781751 YP_002812091.1 CDS nrdD NC_012580.1 414306 416426 D Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 414306..416426 Vibrio cholerae M66-2 7781752 YP_002812092.1 CDS nrdG NC_012580.1 416431 416898 D activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 416431..416898 Vibrio cholerae M66-2 7781753 YP_002812093.1 CDS VCM66_A0472 NC_012580.1 416987 418201 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 416987..418201 Vibrio cholerae M66-2 7781754 YP_002812094.1 CDS VCM66_A0473 NC_012580.1 418259 418942 D Ribosomal protein S6 modification protein 418259..418942 Vibrio cholerae M66-2 7781755 YP_002812095.1 CDS fruA-2 NC_012580.1 419176 420918 R PTS system, fructose-specific IIBC component complement(419176..420918) Vibrio cholerae M66-2 7781756 YP_002812096.1 CDS fruK NC_012580.1 420931 421884 R 1-phosphofructokinase complement(420931..421884) Vibrio cholerae M66-2 7781757 YP_002812097.1 CDS fruB NC_012580.1 421895 423097 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein complement(421895..423097) Vibrio cholerae M66-2 7781758 YP_002812098.1 CDS fruR NC_012580.1 423436 424416 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 423436..424416 Vibrio cholerae M66-2 7781759 YP_002812099.1 CDS VCM66_A0479 NC_012580.1 424470 425609 D putative exonuclease SbcD 424470..425609 Vibrio cholerae M66-2 7781760 YP_002812100.1 CDS VCM66_A0480 NC_012580.1 425611 428652 D putative exonuclease SbcC 425611..428652 Vibrio cholerae M66-2 7781761 YP_002812101.1 CDS luxN NC_012580.1 428749 430809 D sensor histidine kinase/response regulator LuxN 428749..430809 Vibrio cholerae M66-2 7781762 YP_002812102.1 CDS VCM66_A0482 NC_012580.1 431038 432207 R hypothetical protein complement(431038..432207) Vibrio cholerae M66-2 7781763 YP_002812103.1 CDS VCM66_A0483 NC_012580.1 432404 433366 R hypothetical protein complement(432404..433366) Vibrio cholerae M66-2 7781764 YP_002812104.1 CDS VCM66_A0484 NC_012580.1 433343 433447 D hypothetical protein 433343..433447 Vibrio cholerae M66-2 7781765 YP_002812105.1 CDS VCM66_A0485 NC_012580.1 433513 434919 R Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein complement(433513..434919) Vibrio cholerae M66-2 7781766 YP_002812106.1 CDS VCM66_A0486 NC_012580.1 435386 436375 D hypothetical protein 435386..436375 Vibrio cholerae M66-2 7781767 YP_002812107.1 CDS rbgA NC_012580.1 436439 437383 R essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase complement(436439..437383) Vibrio cholerae M66-2 7781768 YP_002812108.1 CDS kup NC_012580.1 437706 439568 D potassium uptake protein, Kup system 437706..439568 Vibrio cholerae M66-2 7781769 YP_002812109.1 CDS ydbK NC_012580.1 439666 442905 R pyruvate-flavoredoxin oxidoreductase complement(439666..442905) Vibrio cholerae M66-2 7781770 YP_002812110.1 CDS VCM66_A0490 NC_012580.1 443008 444501 D sensor histidine kinase 443008..444501 Vibrio cholerae M66-2 7781771 YP_002812111.1 CDS VCM66_A0491 NC_012580.1 444491 445183 D DNA-binding response regulator 444491..445183 Vibrio cholerae M66-2 7781772 YP_002812112.1 CDS tatA-2 NC_012580.1 445383 445619 D tatA protein 445383..445619 Vibrio cholerae M66-2 7781773 YP_002812113.1 CDS VCM66_A0493 NC_012580.1 445835 446551 R DedA family protein complement(445835..446551) Vibrio cholerae M66-2 7781774 YP_002812114.1 CDS VCM66_A0494 NC_012580.1 446672 447052 R hypothetical protein complement(446672..447052) Vibrio cholerae M66-2 7781775 YP_002812115.1 CDS VCM66_A0495 NC_012580.1 447186 448052 R hypothetical protein complement(447186..448052) Vibrio cholerae M66-2 7781776 YP_002812116.1 CDS VCM66_A0496 NC_012580.1 448379 449014 R hypothetical protein complement(448379..449014) Vibrio cholerae M66-2 7781777 YP_002812117.1 CDS VCM66_A0497 NC_012580.1 449401 449946 D putative cytochrome b561 449401..449946 Vibrio cholerae M66-2 7781778 YP_002812118.1 CDS VCM66_A0498 NC_012580.1 449943 450512 D hypothetical protein 449943..450512 Vibrio cholerae M66-2 7781779 YP_002812119.1 CDS VCM66_A0499 NC_012580.1 450620 452071 R putative formate transporter 1 complement(450620..452071) Vibrio cholerae M66-2 7781780 YP_002812120.1 CDS VCM66_A0500 NC_012580.1 452175 452270 D hypothetical protein 452175..452270 Vibrio cholerae M66-2 7781781 YP_002812121.1 CDS VCM66_A0501 NC_012580.1 452288 453193 D LysR family transcriptional regulator 452288..453193 Vibrio cholerae M66-2 7781782 YP_002812122.1 CDS VCM66_A0502 NC_012580.1 453355 453867 D hypothetical protein 453355..453867 Vibrio cholerae M66-2 7781783 YP_002812123.1 CDS VCM66_A0503 NC_012580.1 454099 455763 R hypothetical protein complement(454099..455763) Vibrio cholerae M66-2 7781784 YP_002812124.1 CDS VCM66_A0504 NC_012580.1 455993 457735 D putative 5'-nucleotidase 455993..457735 Vibrio cholerae M66-2 7781785 YP_002812125.1 CDS VCM66_A0505 NC_012580.1 458295 459251 D hypothetical protein 458295..459251 Vibrio cholerae M66-2 7781786 YP_002812126.1 CDS VCM66_A0506 NC_012580.1 459555 459743 D hypothetical protein 459555..459743 Vibrio cholerae M66-2 7781787 YP_002812127.1 CDS VCM66_A0507 NC_012580.1 459772 459921 D hypothetical protein 459772..459921 Vibrio cholerae M66-2 7781788 YP_002812128.1 CDS phnA NC_012580.1 459893 460468 R phnA protein complement(459893..460468) Vibrio cholerae M66-2 7781789 YP_002812129.1 CDS VCM66_A0509 NC_012580.1 460652 461734 D hypothetical protein 460652..461734 Vibrio cholerae M66-2 7781790 YP_002812130.1 CDS VCM66_A0510 NC_012580.1 461788 462018 R hypothetical protein complement(461788..462018) Vibrio cholerae M66-2 7781791 YP_002812131.1 CDS VCM66_A0511 NC_012580.1 462186 464486 R fatty acid cis/trans isomerase complement(462186..464486) Vibrio cholerae M66-2 7781792 YP_002812132.1 CDS VCM66_A0513 NC_012580.1 464899 466131 R oxalate/formate antiporter complement(464899..466131) Vibrio cholerae M66-2 7781793 YP_002812133.1 CDS VCM66_A0514 NC_012580.1 466189 466308 R hypothetical protein complement(466189..466308) Vibrio cholerae M66-2 7781794 YP_002812134.1 CDS VCM66_A0515 NC_012580.1 466542 467096 D hypothetical protein 466542..467096 Vibrio cholerae M66-2 7781795 YP_002812135.1 CDS VCM66_A0516 NC_012580.1 467366 468775 D GGDEF family protein 467366..468775 Vibrio cholerae M66-2 7781796 YP_002812136.1 CDS VCM66_A0517 NC_012580.1 469070 470638 D putative gamma-glutamyltranspeptidase 469070..470638 Vibrio cholerae M66-2 7781295 YP_002812137.1 CDS VCM66_A0518 NC_012580.1 470713 471696 D hypothetical protein 470713..471696 Vibrio cholerae M66-2 7781798 YP_002812138.1 CDS VCM66_A0519 NC_012580.1 471693 472931 R GGDEF family protein complement(471693..472931) Vibrio cholerae M66-2 7781799 YP_002812139.1 CDS VCM66_A0520 NC_012580.1 473287 473661 D hypothetical protein 473287..473661 Vibrio cholerae M66-2 7781800 YP_002812140.1 CDS VCM66_A0521 NC_012580.1 473671 473949 D hypothetical protein 473671..473949 Vibrio cholerae M66-2 7781801 YP_002812141.1 CDS pntA NC_012580.1 474242 475780 D forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 474242..475780 Vibrio cholerae M66-2 7781802 YP_002812142.1 CDS pntB NC_012580.1 475792 477168 D catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 475792..477168 Vibrio cholerae M66-2 7781803 YP_002812143.1 CDS VCM66_A0524 NC_012580.1 477269 478768 D sensor histidine kinase 477269..478768 Vibrio cholerae M66-2 7781804 YP_002812144.1 CDS VCM66_A0525 NC_012580.1 478662 479399 D transcriptional regulator 478662..479399 Vibrio cholerae M66-2 7781805 YP_002812145.1 CDS VCM66_A0526 NC_012580.1 479396 480286 D hypothetical protein 479396..480286 Vibrio cholerae M66-2 7781806 YP_002812146.1 CDS VCM66_A0527 NC_012580.1 480347 481513 D hypothetical protein 480347..481513 Vibrio cholerae M66-2 7781807 YP_002812147.1 CDS VCM66_A0528 NC_012580.1 481554 481715 D hypothetical protein 481554..481715 Vibrio cholerae M66-2 7781808 YP_002812148.1 CDS VCM66_A0529 NC_012580.1 482300 482611 R involved in start site selection during the initiation of translation; translation initiation factor Sui1 complement(482300..482611) Vibrio cholerae M66-2 7781809 YP_002812149.1 CDS VCM66_A0530 NC_012580.1 482619 483002 R hypothetical protein complement(482619..483002) Vibrio cholerae M66-2 7781810 YP_002812150.1 CDS ddl NC_012580.1 483174 484178 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(483174..484178) Vibrio cholerae M66-2 7781811 YP_002812151.1 CDS VCM66_A0532 NC_012580.1 484329 484916 R DamX-related protein complement(484329..484916) Vibrio cholerae M66-2 7781812 YP_002812152.1 CDS VCM66_A0533 NC_012580.1 485123 487804 D hypothetical protein 485123..487804 Vibrio cholerae M66-2 7781813 YP_002812153.1 CDS VCM66_A0534 NC_012580.1 487854 488741 R LysR family transcriptional regulator complement(487854..488741) Vibrio cholerae M66-2 7781814 YP_002812154.1 CDS hutA NC_012580.1 488959 491055 D heme transport protein HutA 488959..491055 Vibrio cholerae M66-2 7781815 YP_002812155.1 CDS VCM66_A0536 NC_012580.1 491171 491278 D hypothetical protein 491171..491278 Vibrio cholerae M66-2 7781816 YP_002812156.1 CDS VCM66_A0537 NC_012580.1 491379 493076 R hypothetical protein complement(491379..493076) Vibrio cholerae M66-2 7781817 YP_002812157.1 CDS VCM66_A0538 NC_012580.1 493157 493390 R hypothetical protein complement(493157..493390) Vibrio cholerae M66-2 7781818 YP_002812158.1 CDS VCM66_A0539 NC_012580.1 493391 493978 R hypothetical protein complement(493391..493978) Vibrio cholerae M66-2 7781819 YP_002812159.1 CDS VCM66_A0540 NC_012580.1 494011 494802 D hypothetical protein 494011..494802 Vibrio cholerae M66-2 7781820 YP_002812160.1 CDS VCM66_A0541 NC_012580.1 494914 495396 R hypothetical protein complement(494914..495396) Vibrio cholerae M66-2 7781821 YP_002812161.1 CDS VCM66_A0542 NC_012580.1 495512 496297 D hypothetical protein 495512..496297 Vibrio cholerae M66-2 7781822 YP_002812162.1 CDS VCM66_A0543 NC_012580.1 496383 497051 R putative glutathione S-transferase complement(496383..497051) Vibrio cholerae M66-2 7781823 YP_002812163.1 CDS VCM66_A0544 NC_012580.1 497063 497674 R putative glutathione S-transferase complement(497063..497674) Vibrio cholerae M66-2 7781824 YP_002812164.1 CDS VCM66_A0545 NC_012580.1 497776 498372 D hypothetical protein 497776..498372 Vibrio cholerae M66-2 7781825 YP_002812165.1 CDS VCM66_A0546 NC_012580.1 498369 498761 D hypothetical protein 498369..498761 Vibrio cholerae M66-2 7781826 YP_002812166.1 CDS VCM66_A0547 NC_012580.1 498845 500437 R putative peptide ABC transporter, ATP-binding protein complement(498845..500437) Vibrio cholerae M66-2 7781827 YP_002812167.1 CDS VCM66_A0548 NC_012580.1 500434 501492 R putative peptide ABC transporter, permease protein complement(500434..501492) Vibrio cholerae M66-2 7781828 YP_002812168.1 CDS VCM66_A0549 NC_012580.1 501489 502571 R putative peptide ABC transporter, permease protein complement(501489..502571) Vibrio cholerae M66-2 7781829 YP_002812169.1 CDS VCM66_A0550 NC_012580.1 502580 504415 R putative peptide ABC transporter, periplasmic peptide-binding protein complement(502580..504415) Vibrio cholerae M66-2 7781830 YP_002812170.1 CDS VCM66_A0551 NC_012580.1 504611 505171 R MutT/nudix family protein complement(504611..505171) Vibrio cholerae M66-2 7781831 YP_002812171.1 CDS VCM66_A0552 NC_012580.1 505225 506157 R hypothetical protein complement(505225..506157) Vibrio cholerae M66-2 7781832 YP_002812172.1 CDS hlx NC_012580.1 506367 506648 D hemolysin 506367..506648 Vibrio cholerae M66-2 7781833 YP_002812173.1 CDS VCM66_A0554 NC_012580.1 506730 507683 R hypothetical protein complement(506730..507683) Vibrio cholerae M66-2 7781834 YP_002812174.1 CDS VCM66_A0555 NC_012580.1 507926 509374 D transporter 507926..509374 Vibrio cholerae M66-2 7781835 YP_002812175.1 CDS VCM66_A0556 NC_012580.1 509386 509508 R hypothetical protein complement(509386..509508) Vibrio cholerae M66-2 7781836 YP_002812176.1 CDS VCM66_A0557 NC_012580.1 509474 510379 R hypothetical protein complement(509474..510379) Vibrio cholerae M66-2 7781837 YP_002812177.1 CDS VCM66_A0558 NC_012580.1 510445 511149 R putative repressor protein PhnR complement(510445..511149) Vibrio cholerae M66-2 7781838 YP_002812178.1 CDS VCM66_A0559 NC_012580.1 511174 512952 R ABC transporter permease complement(511174..512952) Vibrio cholerae M66-2 7781839 YP_002812179.1 CDS VCM66_A0560 NC_012580.1 512885 514096 R ABC transporter ATP-binding protein complement(512885..514096) Vibrio cholerae M66-2 7781840 YP_002812180.1 CDS VCM66_A0561 NC_012580.1 514252 515271 R ABC transporter substrate-binding protein complement(514252..515271) Vibrio cholerae M66-2 7781841 YP_002812181.1 CDS phnW NC_012580.1 515503 516606 D catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate; 2-aminoethylphosphonate--pyruvate transaminase 515503..516606 Vibrio cholerae M66-2 7781842 YP_002812182.1 CDS VCM66_A0563 NC_012580.1 516624 518021 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 516624..518021 Vibrio cholerae M66-2 7781843 YP_002812183.1 CDS phnX NC_012580.1 518028 518843 D catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate; phosphonoacetaldehyde hydrolase 518028..518843 Vibrio cholerae M66-2 7781844 YP_002812184.1 CDS VCM66_A0565 NC_012580.1 519008 519415 D Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 519008..519415 Vibrio cholerae M66-2 7781845 YP_002812185.1 CDS VCM66_A0566 NC_012580.1 519476 520150 R manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase complement(519476..520150) Vibrio cholerae M66-2 7781846 YP_002812186.1 CDS VCM66_A0567 NC_012580.1 520345 520527 D hypothetical protein 520345..520527 Vibrio cholerae M66-2 7781847 YP_002812187.1 CDS VCM66_A0568 NC_012580.1 520532 521182 D isoprenoid biosynthesis protein with amidotransferase-like domain 520532..521182 Vibrio cholerae M66-2 7781848 YP_002812188.1 CDS VCM66_A0569 NC_012580.1 521319 521456 D hypothetical protein 521319..521456 Vibrio cholerae M66-2 7781849 YP_002812189.1 CDS mscL NC_012580.1 521453 521863 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 521453..521863 Vibrio cholerae M66-2 7781850 YP_002812190.1 CDS VCM66_A0571 NC_012580.1 521896 522009 D hypothetical protein 521896..522009 Vibrio cholerae M66-2 7781851 YP_002812191.1 CDS fhs NC_012580.1 522043 523842 D catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 522043..523842 Vibrio cholerae M66-2 7781852 YP_002812192.1 CDS VCM66_A0573 NC_012580.1 523970 525154 D peptide methionine sulfoxide reductase 523970..525154 Vibrio cholerae M66-2 7781853 YP_002812193.1 CDS folE NC_012580.1 525247 525939 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(525247..525939) Vibrio cholerae M66-2 7781854 YP_002812194.1 CDS moeA-2 NC_012580.1 525980 527287 D molybdopterin biosynthesis MoeA protein 525980..527287 Vibrio cholerae M66-2 7781855 YP_002812195.1 CDS moeB NC_012580.1 527290 528054 D ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 527290..528054 Vibrio cholerae M66-2 7781856 YP_002812196.1 CDS VCM66_A0577 NC_012580.1 528238 528606 D hypothetical protein 528238..528606 Vibrio cholerae M66-2 7781857 YP_002812197.1 CDS VCM66_A0578 NC_012580.1 528628 529458 D putative thiosulfate sulfurtransferase SseA 528628..529458 Vibrio cholerae M66-2 7781858 YP_002812198.1 CDS VCM66_A0579 NC_012580.1 529543 530538 R transcriptional regulator, SorC family complement(529543..530538) Vibrio cholerae M66-2 7781859 YP_002812199.1 CDS VCM66_A0580 NC_012580.1 530537 530647 D hypothetical protein 530537..530647 Vibrio cholerae M66-2 7780805 YP_002812200.1 CDS talB NC_012580.1 531131 532081 D transaldolase B 531131..532081 Vibrio cholerae M66-2 7780806 YP_002812201.1 CDS tktA-2 NC_012580.1 532130 534172 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 532130..534172 Vibrio cholerae M66-2 7780807 YP_002812202.1 CDS hasR NC_012580.1 534289 536643 R heme receptor HasR complement(534289..536643) Vibrio cholerae M66-2 7780808 YP_002812203.1 CDS VCM66_A0584 NC_012580.1 536613 536717 D hypothetical protein 536613..536717 Vibrio cholerae M66-2 7780809 YP_002812204.1 CDS VCM66_A0585 NC_012580.1 536857 537369 D putative rRNA methylase 536857..537369 Vibrio cholerae M66-2 7780810 YP_002812205.1 CDS VCM66_A0586 NC_012580.1 537807 539981 D SecA-related protein 537807..539981 Vibrio cholerae M66-2 7780811 YP_002812206.1 CDS VCM66_A0587 NC_012580.1 540252 541292 R hypothetical protein complement(540252..541292) Vibrio cholerae M66-2 7780812 YP_002812207.1 CDS VCM66_A0588 NC_012580.1 541305 542276 R D-3-phosphoglycerate dehydrogenase-related protein complement(541305..542276) Vibrio cholerae M66-2 7780813 YP_002812208.1 CDS VCM66_A0589 NC_012580.1 542292 542807 R hypothetical protein complement(542292..542807) Vibrio cholerae M66-2 7780814 YP_002812209.1 CDS VCM66_A0590 NC_012580.1 542840 543289 R MutT/nudix family protein complement(542840..543289) Vibrio cholerae M66-2 7780815 YP_002812210.1 CDS glpM NC_012580.1 543329 543679 R glpM protein complement(543329..543679) Vibrio cholerae M66-2 7780816 YP_002812211.1 CDS VCM66_A0592 NC_012580.1 543871 544596 D hypothetical protein 543871..544596 Vibrio cholerae M66-2 7780817 YP_002812212.1 CDS VCM66_A0593 NC_012580.1 544606 545547 D LysR family transcriptional regulator 544606..545547 Vibrio cholerae M66-2 7780818 YP_002812213.1 CDS VCM66_A0594 NC_012580.1 545544 545834 R hypothetical protein complement(545544..545834) Vibrio cholerae M66-2 7780819 YP_002812214.1 CDS VCM66_A0595 NC_012580.1 545838 546491 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(545838..546491) Vibrio cholerae M66-2 7780820 YP_002812215.1 CDS VCM66_A0596 NC_012580.1 546707 549910 R transporter, AcrB/D/F family complement(546707..549910) Vibrio cholerae M66-2 7780821 YP_002812216.1 CDS VCM66_A0597 NC_012580.1 549867 550871 R AcrA/AcrE family protein complement(549867..550871) Vibrio cholerae M66-2 7780822 YP_002812217.1 CDS VCM66_A0598 NC_012580.1 550981 551445 R hypothetical protein complement(550981..551445) Vibrio cholerae M66-2 7780823 YP_002812218.1 CDS VCM66_A0599 NC_012580.1 551450 551869 R hypothetical protein complement(551450..551869) Vibrio cholerae M66-2 7780824 YP_002812219.1 CDS VCM66_A0600 NC_012580.1 551886 552203 R transcriptional regulator, ArsR family complement(551886..552203) Vibrio cholerae M66-2 7780825 YP_002812220.1 CDS VCM66_A0601 NC_012580.1 552277 552543 D hypothetical protein 552277..552543 Vibrio cholerae M66-2 7780826 YP_002812221.1 CDS VCM66_A0602 NC_012580.1 552609 554312 D putative NADH oxidase 552609..554312 Vibrio cholerae M66-2 7780827 YP_002812222.1 CDS VCM66_A0603 NC_012580.1 554405 554785 R hypothetical protein complement(554405..554785) Vibrio cholerae M66-2 7780828 YP_002812223.1 CDS VCM66_A0604 NC_012580.1 554901 556718 R hemolysin complement(554901..556718) Vibrio cholerae M66-2 7780829 YP_002812224.1 CDS VCM66_A0605 NC_012580.1 556643 557089 R hypothetical protein complement(556643..557089) Vibrio cholerae M66-2 7780830 YP_002812225.1 CDS VCM66_A0606 NC_012580.1 557100 557846 R hypothetical protein complement(557100..557846) Vibrio cholerae M66-2 7780831 YP_002812226.1 CDS VCM66_A0607 NC_012580.1 557846 558388 R hypothetical protein complement(557846..558388) Vibrio cholerae M66-2 7780832 YP_002812227.1 CDS VCM66_A0608 NC_012580.1 558477 559613 R hypothetical protein complement(558477..559613) Vibrio cholerae M66-2 7780833 YP_002812228.1 CDS VCM66_A0609 NC_012580.1 559610 560191 R hypothetical protein complement(559610..560191) Vibrio cholerae M66-2 7780834 YP_002812229.1 CDS VCM66_A0610 NC_012580.1 560463 560900 D hypothetical protein 560463..560900 Vibrio cholerae M66-2 7780835 YP_002812230.1 CDS scrA NC_012580.1 561066 562505 R PTS system, sucrose-specific IIBC component complement(561066..562505) Vibrio cholerae M66-2 7780836 YP_002812231.1 CDS VCM66_A0612 NC_012580.1 562806 563798 D putative sucrose operon repressor ScrR 562806..563798 Vibrio cholerae M66-2 7780837 YP_002812232.1 CDS cscA NC_012580.1 563874 565520 D sucrose-6-phosphate dehydrogenase 563874..565520 Vibrio cholerae M66-2 7780838 YP_002812233.1 CDS cscK NC_012580.1 565642 566613 R phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least; aminoimidazole riboside kinase complement(565642..566613) Vibrio cholerae M66-2 7780839 YP_002812234.1 CDS glpD NC_012580.1 566960 568498 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 566960..568498 Vibrio cholerae M66-2 7780840 YP_002812235.1 CDS VCM66_A0616 NC_012580.1 568600 570210 R methyl-accepting chemotaxis protein complement(568600..570210) Vibrio cholerae M66-2 7780841 YP_002812236.1 CDS VCM66_A0617 NC_012580.1 570396 571019 R protein F-related protein complement(570396..571019) Vibrio cholerae M66-2 7780842 YP_002812237.1 CDS VCM66_A0618 NC_012580.1 571020 571142 R hypothetical protein complement(571020..571142) Vibrio cholerae M66-2 7780843 YP_002812238.1 CDS VCM66_A0619 NC_012580.1 571232 571705 D peptidyl-prolyl cis-trans isomerase-related protein 571232..571705 Vibrio cholerae M66-2 7780844 YP_002812239.1 CDS VCM66_A0620 NC_012580.1 571786 572424 R CbbY family protein complement(571786..572424) Vibrio cholerae M66-2 7780845 YP_002812240.1 CDS VCM66_A0621 NC_012580.1 572571 574334 D methyl-accepting chemotaxis protein 572571..574334 Vibrio cholerae M66-2 7780846 YP_002812241.1 CDS VCM66_A0622 NC_012580.1 574275 574463 R hypothetical protein complement(574275..574463) Vibrio cholerae M66-2 7780847 YP_002812242.1 CDS dcuC NC_012580.1 574728 576107 D responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 574728..576107 Vibrio cholerae M66-2 7780848 YP_002812243.1 CDS sdaA-2 NC_012580.1 576205 577635 R L-serine dehydratase 1 complement(576205..577635) Vibrio cholerae M66-2 7780849 YP_002812244.1 CDS VCM66_A0625 NC_012580.1 577586 579127 R sodium/solute symporter complement(577586..579127) Vibrio cholerae M66-2 7780850 YP_002812245.1 CDS VCM66_A0626 NC_012580.1 579166 579273 R hypothetical protein complement(579166..579273) Vibrio cholerae M66-2 7780851 YP_002812246.1 CDS VCM66_A0627 NC_012580.1 579466 580761 D sugar transporter family protein 579466..580761 Vibrio cholerae M66-2 7780852 YP_002812247.1 CDS VCM66_A0628 NC_012580.1 580720 580875 R hypothetical protein complement(580720..580875) Vibrio cholerae M66-2 7780853 YP_002812248.1 CDS VCM66_A0629 NC_012580.1 580858 581874 D hypothetical protein 580858..581874 Vibrio cholerae M66-2 7780854 YP_002812249.1 CDS VCM66_A0630 NC_012580.1 581974 582084 D hypothetical protein 581974..582084 Vibrio cholerae M66-2 7780855 YP_002812250.1 CDS VCM66_A0631 NC_012580.1 582114 583145 D transcriptional regulator, LacI family 582114..583145 Vibrio cholerae M66-2 7780856 YP_002812251.1 CDS narP NC_012580.1 583196 583822 R nitrate/nitrite response regulator NarP complement(583196..583822) Vibrio cholerae M66-2 7780857 YP_002812252.1 CDS narQ NC_012580.1 583812 585563 R nitrate/nitrite sensor protein NarQ complement(583812..585563) Vibrio cholerae M66-2 7780858 YP_002812253.1 CDS napF NC_012580.1 585721 586227 D iron-sulfur cluster-binding protein NapF 585721..586227 Vibrio cholerae M66-2 7780859 YP_002812254.1 CDS napD NC_012580.1 586233 586574 D napD protein 586233..586574 Vibrio cholerae M66-2 7780860 YP_002812255.1 CDS napA NC_012580.1 586571 589060 D periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 586571..589060 Vibrio cholerae M66-2 7780861 YP_002812256.1 CDS napB NC_012580.1 589067 589582 D periplasmic nitrate reductase, cytochrome c-type protein 589067..589582 Vibrio cholerae M66-2 7780862 YP_002812257.1 CDS napC NC_012580.1 589600 590175 D periplasmic nitrate reductase, cytochrome c-type protein 589600..590175 Vibrio cholerae M66-2 7780863 YP_002812258.1 CDS VCM66_A0639 NC_012580.1 590359 591654 R hypothetical protein complement(590359..591654) Vibrio cholerae M66-2 7780864 YP_002812259.1 CDS uhpA NC_012580.1 591813 592439 D transcriptional regulator UhpA 591813..592439 Vibrio cholerae M66-2 7780865 YP_002812260.1 CDS uhpB NC_012580.1 592442 594025 D sensor protein UhpB 592442..594025 Vibrio cholerae M66-2 7780866 YP_002812261.1 CDS uhpC NC_012580.1 594093 595403 D membrane protein regulates uhpT expression; regulatory protein UhpC 594093..595403 Vibrio cholerae M66-2 7780867 YP_002812262.1 CDS VCM66_A0643 NC_012580.1 595516 596550 D iron(III) ABC transporter, periplasmic iron-compound-binding protein 595516..596550 Vibrio cholerae M66-2 7780868 YP_002812263.1 CDS VCM66_A0644 NC_012580.1 596654 598756 D iron(III) ABC transporter, permease protein 596654..598756 Vibrio cholerae M66-2 7780869 YP_002812264.1 CDS fbpC NC_012580.1 598768 599823 D Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import; ferric transporter ATP-binding subunit 598768..599823 Vibrio cholerae M66-2 7780870 YP_002812265.1 CDS phaC NC_012580.1 599909 601684 R polyhydroxyalkanoic acid synthase complement(599909..601684) Vibrio cholerae M66-2 7780871 YP_002812266.1 CDS VCM66_A0647 NC_012580.1 601742 602089 R hypothetical protein complement(601742..602089) Vibrio cholerae M66-2 7780872 YP_002812267.1 CDS VCM66_A0648 NC_012580.1 602119 603324 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(602119..603324) Vibrio cholerae M66-2 7780873 YP_002812268.1 CDS VCM66_A0649 NC_012580.1 603337 604077 R catalyzes the conversion of 3-hydroxyacyl-CoA to 3-oxyacyl-CoA; acetoacetyl-CoA reductase complement(603337..604077) Vibrio cholerae M66-2 7780874 YP_002812269.1 CDS secF-2 NC_012580.1 604748 605650 R protein-export membrane protein SecF complement(604748..605650) Vibrio cholerae M66-2 7780875 YP_002812270.1 CDS secD NC_012580.1 605654 607492 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(605654..607492) Vibrio cholerae M66-2 7780876 YP_002812271.1 CDS VCM66_A0652 NC_012580.1 607564 608019 R hypothetical protein complement(607564..608019) Vibrio cholerae M66-2 7780877 YP_002812272.1 CDS VCM66_A0653 NC_012580.1 608096 608767 R hypothetical protein complement(608096..608767) Vibrio cholerae M66-2 7780878 YP_002812273.1 CDS VCM66_A0654 NC_012580.1 608802 608912 R hypothetical protein complement(608802..608912) Vibrio cholerae M66-2 7780879 YP_002812274.1 CDS VCM66_A0655 NC_012580.1 609125 611053 D sensory box/GGDEF family protein 609125..611053 Vibrio cholerae M66-2 7780880 YP_002812275.1 CDS VCM66_A0656 NC_012580.1 611050 611142 D hypothetical protein 611050..611142 Vibrio cholerae M66-2 7780881 YP_002812276.1 CDS glgC NC_012580.1 611356 612579 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 611356..612579 Vibrio cholerae M66-2 7780882 YP_002812277.1 CDS VCM66_A0658 NC_012580.1 612845 616000 R chitodextrinase complement(612845..616000) Vibrio cholerae M66-2 7780883 YP_002812278.1 CDS VCM66_A0659 NC_012580.1 616034 616165 R hypothetical protein complement(616034..616165) Vibrio cholerae M66-2 7780884 YP_002812279.1 CDS VCM66_A0660 NC_012580.1 616672 617820 D iron-containing alcohol dehydrogenase 616672..617820 Vibrio cholerae M66-2 7780885 YP_002812280.1 CDS VCM66_A0661 NC_012580.1 617899 618588 D hypothetical protein 617899..618588 Vibrio cholerae M66-2 7780886 YP_002812281.1 CDS VCM66_A0662 NC_012580.1 618585 619904 R phosphoglycerate transport system transcriptional regulatory protein PgtA complement(618585..619904) Vibrio cholerae M66-2 7780887 YP_002812282.1 CDS VCM66_A0663 NC_012580.1 619822 622191 R putative phosphoglycerate transport regulatory protein PgtB complement(619822..622191) Vibrio cholerae M66-2 7780888 YP_002812283.1 CDS VCM66_A0664 NC_012580.1 622188 623510 R putative phosphoglycerate transport regulatory protein PgtC complement(622188..623510) Vibrio cholerae M66-2 7780889 YP_002812284.1 CDS VCM66_A0665 NC_012580.1 623757 625136 D putative regulatory protein UhpC 623757..625136 Vibrio cholerae M66-2 7780890 YP_002812285.1 CDS pykA-2 NC_012580.1 625258 626718 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 625258..626718 Vibrio cholerae M66-2 7780891 YP_002812286.1 CDS torS NC_012580.1 626837 629899 R sensor protein TorS complement(626837..629899) Vibrio cholerae M66-2 7780892 YP_002812287.1 CDS torT NC_012580.1 629822 630871 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 629822..630871 Vibrio cholerae M66-2 7780893 YP_002812288.1 CDS mgsA NC_012580.1 630926 631381 D catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 630926..631381 Vibrio cholerae M66-2 7780894 YP_002812289.1 CDS pncA NC_012580.1 631450 632070 R pyrazinamidase/nicotinamidase complement(631450..632070) Vibrio cholerae M66-2 7780895 YP_002812290.1 CDS VCM66_A0671 NC_012580.1 632192 632308 R hypothetical protein complement(632192..632308) Vibrio cholerae M66-2 7780896 YP_002812291.1 CDS dgkA NC_012580.1 632375 632731 D diacylglycerol kinase 632375..632731 Vibrio cholerae M66-2 7780897 YP_002812292.1 CDS VCM66_A0673 NC_012580.1 632871 633188 D hypothetical protein 632871..633188 Vibrio cholerae M66-2 7780898 YP_002812293.1 CDS VCM66_A0674 NC_012580.1 633181 633717 D hypothetical protein 633181..633717 Vibrio cholerae M66-2 7780899 YP_002812294.1 CDS helD NC_012580.1 633773 635872 R catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV complement(633773..635872) Vibrio cholerae M66-2 7780900 YP_002812295.1 CDS VCM66_A0676 NC_012580.1 636023 638200 D hypothetical protein 636023..638200 Vibrio cholerae M66-2 7780901 YP_002812296.1 CDS VCM66_A0677 NC_012580.1 638210 639157 R sensor histide kinase complement(638210..639157) Vibrio cholerae M66-2 7780902 YP_002812297.1 CDS VCM66_A0678 NC_012580.1 639154 639729 R guanylate cyclase-related protein complement(639154..639729) Vibrio cholerae M66-2 7780903 YP_002812298.1 CDS VCM66_A0679 NC_012580.1 639857 640168 D hypothetical protein 639857..640168 Vibrio cholerae M66-2 7780904 YP_002812299.1 CDS VCM66_A0680 NC_012580.1 640225 640515 D hypothetical protein 640225..640515 Vibrio cholerae M66-2 7780905 YP_002812300.1 CDS hmgA NC_012580.1 640545 641855 D 3-hydroxy-3-methylglutaryl CoA reductase 640545..641855 Vibrio cholerae M66-2 7780906 YP_002812301.1 CDS modC NC_012580.1 641954 643054 R Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein complement(641954..643054) Vibrio cholerae M66-2 7780907 YP_002812302.1 CDS modB NC_012580.1 643068 643766 R part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease complement(643068..643766) Vibrio cholerae M66-2 7780908 YP_002812303.1 CDS modA NC_012580.1 643767 644531 R molybdenum ABC transporter, periplasmic molybdate-binding protein complement(643767..644531) Vibrio cholerae M66-2 7780909 YP_002812304.1 CDS cobQ NC_012580.1 644537 646045 R catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase complement(644537..646045) Vibrio cholerae M66-2 7780910 YP_002812305.1 CDS VCM66_A0686 NC_012580.1 646594 648765 R hypothetical protein complement(646594..648765) Vibrio cholerae M66-2 7780911 YP_002812306.1 CDS VCM66_A0687 NC_012580.1 648758 649381 R hypothetical protein complement(648758..649381) Vibrio cholerae M66-2 7780912 YP_002812307.1 CDS VCM66_A0688 NC_012580.1 649384 651213 R hypothetical protein complement(649384..651213) Vibrio cholerae M66-2 7780913 YP_002812308.1 CDS VCM66_A0689 NC_012580.1 651912 652217 R hypothetical protein complement(651912..652217) Vibrio cholerae M66-2 7780914 YP_002812309.1 CDS VCM66_A0690 NC_012580.1 652420 652818 D hypothetical protein 652420..652818 Vibrio cholerae M66-2 7780915 YP_002812310.1 CDS VCM66_A0691 NC_012580.1 652859 653011 D hypothetical protein 652859..653011 Vibrio cholerae M66-2 7780916 YP_002812311.1 CDS VCM66_A0692 NC_012580.1 653049 653588 D hypothetical protein 653049..653588 Vibrio cholerae M66-2 7780917 YP_002812312.1 CDS VCM66_A0693 NC_012580.1 653787 654497 D hypothetical protein 653787..654497 Vibrio cholerae M66-2 7780918 YP_002812313.1 CDS luxQ NC_012580.1 654489 657062 R sensor histidine kinase LuxQ complement(654489..657062) Vibrio cholerae M66-2 7780919 YP_002812314.1 CDS luxP NC_012580.1 657080 658174 R luxP protein complement(657080..658174) Vibrio cholerae M66-2 7780920 YP_002812315.1 CDS VCM66_A0696 NC_012580.1 658386 659627 R hypothetical protein complement(658386..659627) Vibrio cholerae M66-2 7780921 YP_002812316.1 CDS VCM66_A0697 NC_012580.1 659648 659953 R hypothetical protein complement(659648..659953) Vibrio cholerae M66-2 7780922 YP_002812317.1 CDS VCM66_A0698 NC_012580.1 659970 660620 R hypothetical protein complement(659970..660620) Vibrio cholerae M66-2 7780923 YP_002812318.1 CDS VCM66_A0699 NC_012580.1 660662 660859 R hypothetical protein complement(660662..660859) Vibrio cholerae M66-2 7780924 YP_002812319.1 CDS VCM66_A0700 NC_012580.1 661047 661367 D hypothetical protein 661047..661367 Vibrio cholerae M66-2 7780925 YP_002812320.1 CDS VCM66_A0701 NC_012580.1 661367 661516 D hypothetical protein 661367..661516 Vibrio cholerae M66-2 7780926 YP_002812321.1 CDS VCM66_A0702 NC_012580.1 661780 662031 D hypothetical protein 661780..662031 Vibrio cholerae M66-2 7780927 YP_002812322.1 CDS glpK NC_012580.1 662112 663629 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(662112..663629) Vibrio cholerae M66-2 7780928 YP_002812323.1 CDS glpF NC_012580.1 663741 664595 R glycerol uptake facilitator protein complement(663741..664595) Vibrio cholerae M66-2 7780929 YP_002812324.1 CDS VCM66_A0705 NC_012580.1 664933 665094 R hypothetical protein complement(664933..665094) Vibrio cholerae M66-2 7780930 YP_002812325.1 CDS glpA NC_012580.1 665250 666893 D anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 665250..666893 Vibrio cholerae M66-2 7780931 YP_002812326.1 CDS glpB NC_012580.1 666890 668200 D sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 666890..668200 Vibrio cholerae M66-2 7780932 YP_002812327.1 CDS glpC NC_012580.1 668197 669438 D anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 668197..669438 Vibrio cholerae M66-2 7780933 YP_002812328.1 CDS fabH-2 NC_012580.1 669580 670791 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis; 3-oxoacyl-(acyl carrier protein) synthase III complement(669580..670791) Vibrio cholerae M66-2 7780934 YP_002812329.1 CDS trxC NC_012580.1 670837 671271 D thioredoxin 2 670837..671271 Vibrio cholerae M66-2 7780935 YP_002812330.1 CDS VCM66_A0712 NC_012580.1 671460 672614 D hypothetical protein 671460..672614 Vibrio cholerae M66-2 7780936 YP_002812331.1 CDS VCM66_A0713 NC_012580.1 672699 673529 D lipase-related protein 672699..673529 Vibrio cholerae M66-2 7780937 YP_002812332.1 CDS VCM66_A0714 NC_012580.1 673963 674463 R hypothetical protein complement(673963..674463) Vibrio cholerae M66-2 7781297 YP_002812333.1 CDS VCM66_A0715 NC_012580.1 674578 675543 D LysR family transcriptional regulator 674578..675543 Vibrio cholerae M66-2 7780939 YP_002812334.1 CDS artM NC_012580.1 675596 676264 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(675596..676264) Vibrio cholerae M66-2 7780940 YP_002812335.1 CDS artQ NC_012580.1 676261 676950 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(676261..676950) Vibrio cholerae M66-2 7780941 YP_002812336.1 CDS artI NC_012580.1 676952 677683 R arginine ABC transporter, periplasmic arginine-binding protein complement(676952..677683) Vibrio cholerae M66-2 7780942 YP_002812337.1 CDS artP NC_012580.1 677757 678500 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(677757..678500) Vibrio cholerae M66-2 7780943 YP_002812338.1 CDS VCM66_A0720 NC_012580.1 678939 679037 D hypothetical protein 678939..679037 Vibrio cholerae M66-2 7781298 YP_002812339.1 CDS yieM NC_012580.1 679078 680523 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(679078..680523) Vibrio cholerae M66-2 7780945 YP_002812340.1 CDS VCM66_A0722 NC_012580.1 680532 682190 R hypothetical protein complement(680532..682190) Vibrio cholerae M66-2 7780946 YP_002812341.1 CDS VCM66_A0723 NC_012580.1 682485 683042 D MutT/nudix family protein 682485..683042 Vibrio cholerae M66-2 7780947 YP_002812342.1 CDS ybjU NC_012580.1 683027 684058 D L-allo-threonine aldolase 683027..684058 Vibrio cholerae M66-2 7780948 YP_002812343.1 CDS VCM66_A0725 NC_012580.1 684055 684495 D cytochrome c554 684055..684495 Vibrio cholerae M66-2 7780949 YP_002812344.1 CDS VCM66_A0726 NC_012580.1 684599 685333 D TetR family transcriptional regulator 684599..685333 Vibrio cholerae M66-2 7780950 YP_002812345.1 CDS VCM66_A0727 NC_012580.1 685433 686701 R ATP-dependent RNA helicase, DEAD box family complement(685433..686701) Vibrio cholerae M66-2 7780951 YP_002812346.1 CDS VCM66_A0728 NC_012580.1 686738 687319 R hypothetical protein complement(686738..687319) Vibrio cholerae M66-2 7780952 YP_002812347.1 CDS VCM66_A0729 NC_012580.1 687356 687475 R hypothetical protein complement(687356..687475) Vibrio cholerae M66-2 7780953 YP_002812348.1 CDS VCM66_A0730 NC_012580.1 687503 687604 R hypothetical protein complement(687503..687604) Vibrio cholerae M66-2 7780954 YP_002812349.1 CDS tyrP NC_012580.1 687839 689041 D tyrosine-specific transport protein 687839..689041 Vibrio cholerae M66-2 7780955 YP_002812350.1 CDS VCM66_A0732 NC_012580.1 689269 690690 D methyl-accepting chemotaxis protein 689269..690690 Vibrio cholerae M66-2 7780956 YP_002812351.1 CDS galE-2 NC_012580.1 690776 691792 R UDP-glucose 4-epimerase complement(690776..691792) Vibrio cholerae M66-2 7780957 YP_002812352.1 CDS VCM66_A0735 NC_012580.1 692112 692852 D LamB/YcsF family protein 692112..692852 Vibrio cholerae M66-2 7780958 YP_002812353.1 CDS VCM66_A0736 NC_012580.1 692856 693566 D hypothetical protein 692856..693566 Vibrio cholerae M66-2 7780959 YP_002812354.1 CDS VCM66_A0737 NC_012580.1 693676 694605 D hypothetical protein 693676..694605 Vibrio cholerae M66-2 7780960 YP_002812355.1 CDS VCM66_A0738 NC_012580.1 694657 696090 R hypothetical protein complement(694657..696090) Vibrio cholerae M66-2 7780961 YP_002812356.1 CDS ugd NC_012580.1 696199 697365 R UDP-glucose 6-dehydrogenase complement(696199..697365) Vibrio cholerae M66-2 7780962 YP_002812357.1 CDS VCM66_A0740 NC_012580.1 697754 700201 R hypothetical protein complement(697754..700201) Vibrio cholerae M66-2 7780963 YP_002812358.1 CDS VCM66_A0741 NC_012580.1 700198 700875 R ABC transporter ATP-binding protein complement(700198..700875) Vibrio cholerae M66-2 7780964 YP_002812359.1 CDS VCM66_A0742 NC_012580.1 700826 701473 D arylesterase 700826..701473 Vibrio cholerae M66-2 7780965 YP_002812360.1 CDS VCM66_A0743 NC_012580.1 701563 702771 D enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity; trans-2-enoyl-CoA reductase 701563..702771 Vibrio cholerae M66-2 7780966 YP_002812361.1 CDS VCM66_A0744 NC_012580.1 702940 704823 D GGDEF family protein 702940..704823 Vibrio cholerae M66-2 7780967 YP_002812362.1 CDS VCM66_A0745 NC_012580.1 704949 706598 D hypothetical protein 704949..706598 Vibrio cholerae M66-2 7780968 YP_002812363.1 CDS VCM66_A0746 NC_012580.1 706595 706699 R hypothetical protein complement(706595..706699) Vibrio cholerae M66-2 7780969 YP_002812364.1 CDS VCM66_A0747 NC_012580.1 706756 707385 R DnaJ-related protein complement(706756..707385) Vibrio cholerae M66-2 7780970 YP_002812365.1 CDS VCM66_A0748 NC_012580.1 707621 708208 D hypothetical protein 707621..708208 Vibrio cholerae M66-2 7780971 YP_002812366.1 CDS VCM66_A0749 NC_012580.1 708382 709761 D hypothetical protein 708382..709761 Vibrio cholerae M66-2 7780972 YP_002812367.1 CDS orfB NC_012580.1 709754 710626 R ISVch4 transposase, OrfB complement(709754..710626) Vibrio cholerae M66-2 7780973 YP_002812368.1 CDS orfA NC_012580.1 710623 710967 R ISVch4 transposase, OrfA complement(710623..710967) Vibrio cholerae M66-2 7780974 YP_002812369.1 CDS VCM66_A0752 NC_012580.1 711044 711526 D hypothetical protein 711044..711526 Vibrio cholerae M66-2 7780975 YP_002812370.1 CDS VCM66_A0753 NC_012580.1 711527 711820 D hypothetical protein 711527..711820 Vibrio cholerae M66-2 7780976 YP_002812371.1 CDS VCM66_A0754 NC_012580.1 712035 712991 D putative resolvase 712035..712991 Vibrio cholerae M66-2 7780977 YP_002812372.1 CDS VCM66_A0755 NC_012580.1 713078 713176 D hypothetical protein 713078..713176 Vibrio cholerae M66-2 7780978 YP_002812373.1 CDS VCM66_A0756 NC_012580.1 713229 713450 D hypothetical protein 713229..713450 Vibrio cholerae M66-2 7780979 YP_002812374.1 CDS VCM66_A0757 NC_012580.1 713646 714326 R CbbY family protein complement(713646..714326) Vibrio cholerae M66-2 7780980 YP_002812375.1 CDS VCM66_A0758 NC_012580.1 714465 714971 R hypothetical protein complement(714465..714971) Vibrio cholerae M66-2 7780981 YP_002812376.1 CDS creA NC_012580.1 715293 715775 D creA protein 715293..715775 Vibrio cholerae M66-2 7780982 YP_002812377.1 CDS gsk-2 NC_012580.1 715894 717198 D inosine-guanosine kinase 715894..717198 Vibrio cholerae M66-2 7780983 YP_002812378.1 CDS VCM66_A0761 NC_012580.1 717284 719257 R hypothetical protein complement(717284..719257) Vibrio cholerae M66-2 7780984 YP_002812379.1 CDS VCM66_A0762 NC_012580.1 719339 720331 R putative serine protease complement(719339..720331) Vibrio cholerae M66-2 7780985 YP_002812380.1 CDS deaD NC_012580.1 720475 722466 R ATP-dependent RNA helicase DeaD complement(720475..722466) Vibrio cholerae M66-2 7780986 YP_002812381.1 CDS rnb NC_012580.1 722780 724816 D Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 722780..724816 Vibrio cholerae M66-2 7780987 YP_002812382.1 CDS VCM66_A0765 NC_012580.1 724911 725384 R hypothetical protein complement(724911..725384) Vibrio cholerae M66-2 7780988 YP_002812383.1 CDS VCM66_A0766 NC_012580.1 725472 726308 D ABC transporter substrate-binding protein 725472..726308 Vibrio cholerae M66-2 7780989 YP_002812384.1 CDS VCM66_A0767 NC_012580.1 726454 727146 R NodN-related protein complement(726454..727146) Vibrio cholerae M66-2 7780990 YP_002812385.1 CDS VCM66_A0768 NC_012580.1 727420 728970 R hypothetical protein complement(727420..728970) Vibrio cholerae M66-2 7780991 YP_002812386.1 CDS VCM66_A0769 NC_012580.1 729296 729433 R hypothetical protein complement(729296..729433) Vibrio cholerae M66-2 7780992 YP_002812387.1 CDS VCM66_A0770 NC_012580.1 729464 730921 D GbpA; plays a role mediating bacterial attachment and colonization of zooplankton and/or intestinal epithelium; in Vibrio cholerae this protein probably binds directly N-acetylglucosamine residues in chitin, glycoproteins and lipids on intestinal epithelial cells; N-acetylglucosamine-binding protein A 729464..730921 Vibrio cholerae M66-2 7780993 YP_002812388.1 CDS VCM66_A0771 NC_012580.1 731249 732679 D leucine aminopeptidase-related protein 731249..732679 Vibrio cholerae M66-2 7780994 YP_002812389.1 CDS VCM66_A0772 NC_012580.1 732714 734219 D aminopeptidase 732714..734219 Vibrio cholerae M66-2 7780995 YP_002812390.1 CDS speB NC_012580.1 734407 735336 R catalyzes the formation of putrescine from agmatine; agmatinase complement(734407..735336) Vibrio cholerae M66-2 7780996 YP_002812391.1 CDS speA NC_012580.1 735337 737322 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(735337..737322) Vibrio cholerae M66-2 7780997 YP_002812392.1 CDS VCM66_A0775 NC_012580.1 737392 737538 R hypothetical protein complement(737392..737538) Vibrio cholerae M66-2 7780998 YP_002812393.1 CDS VCM66_A0776 NC_012580.1 737670 738254 D hypothetical protein 737670..738254 Vibrio cholerae M66-2 7780999 YP_002812394.1 CDS VCM66_A0777 NC_012580.1 738257 739603 D putative magnesium transporter MgtE 738257..739603 Vibrio cholerae M66-2 7781000 YP_002812395.1 CDS groES NC_012580.1 739805 740095 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 739805..740095 Vibrio cholerae M66-2 7781001 YP_002812396.1 CDS groEL NC_012580.1 740124 741716 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth; chaperonin GroEL 740124..741716 Vibrio cholerae M66-2 7781002 YP_002812397.1 CDS VCM66_A0780 NC_012580.1 741749 741955 D hypothetical protein 741749..741955 Vibrio cholerae M66-2 7781003 YP_002812398.1 CDS VCM66_A0781 NC_012580.1 742036 743460 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; aspartate kinase complement(742036..743460) Vibrio cholerae M66-2 7781004 YP_002812399.1 CDS ectC NC_012580.1 743457 743873 R N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid; L-ectoine synthase complement(743457..743873) Vibrio cholerae M66-2 7781005 YP_002812400.1 CDS ectB NC_012580.1 743909 745174 R catalyzes the reversible formation of diaminobutyrate and 2-oxoglutarate from glutamate and L-aspartic beta-semialdehyde; diaminobutyrate--2-oxoglutarate aminotransferase complement(743909..745174) Vibrio cholerae M66-2 7781006 YP_002812401.1 CDS ectA NC_012580.1 745198 745719 R L-2,4-diaminobutyric acid acetyltransferase complement(745198..745719) Vibrio cholerae M66-2 7781007 YP_002812402.1 CDS VCM66_A0785 NC_012580.1 745833 745949 R hypothetical protein complement(745833..745949) Vibrio cholerae M66-2 7781008 YP_002812403.1 CDS phhB NC_012580.1 746420 746749 R 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase complement(746420..746749) Vibrio cholerae M66-2 7781009 YP_002812404.1 CDS phhA NC_012580.1 746739 747608 R phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin; phenylalanine 4-monooxygenase complement(746739..747608) Vibrio cholerae M66-2 7781010 YP_002812405.1 CDS acs-2 NC_012580.1 747767 749746 D AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase 747767..749746 Vibrio cholerae M66-2 7781011 YP_002812406.1 CDS VCM66_A0789 NC_012580.1 749820 750794 D LysR family transcriptional regulator 749820..750794 Vibrio cholerae M66-2 7781012 YP_002812407.1 CDS VCM66_A0790 NC_012580.1 750796 750990 D hypothetical protein 750796..750990 Vibrio cholerae M66-2 7781013 YP_002812408.1 CDS VCM66_A0791 NC_012580.1 751294 751926 R putative methyltransferase complement(751294..751926) Vibrio cholerae M66-2 7781014 YP_002812409.1 CDS VCM66_A0792 NC_012580.1 752068 752946 D LysR family transcriptional regulator 752068..752946 Vibrio cholerae M66-2 7781015 YP_002812410.1 CDS VCM66_A0793 NC_012580.1 753083 754036 D hypothetical protein 753083..754036 Vibrio cholerae M66-2 7781016 YP_002812411.1 CDS VCM66_A0794 NC_012580.1 754068 755054 R hypothetical protein complement(754068..755054) Vibrio cholerae M66-2 7781017 YP_002812412.1 CDS VCM66_A0795 NC_012580.1 755092 755670 R hexapeptide-repeat containing-acetyltransferase complement(755092..755670) Vibrio cholerae M66-2 7781018 YP_002812413.1 CDS VCM66_A0796 NC_012580.1 755808 757121 R putative hemolysin complement(755808..757121) Vibrio cholerae M66-2 7781019 YP_002812414.1 CDS VCM66_A0797 NC_012580.1 757276 757680 R hypothetical protein complement(757276..757680) Vibrio cholerae M66-2 7781020 YP_002812415.1 CDS VCM66_A0798 NC_012580.1 757702 757833 D hypothetical protein 757702..757833 Vibrio cholerae M66-2 7781021 YP_002812416.1 CDS VCM66_A0799 NC_012580.1 758573 759058 D putative deoxycytidylate deaminase 758573..759058 Vibrio cholerae M66-2 7781022 YP_002812417.1 CDS VCM66_A0800 NC_012580.1 759112 759243 R hypothetical protein complement(759112..759243) Vibrio cholerae M66-2 7781023 YP_002812418.1 CDS VCM66_A0801 NC_012580.1 759488 759640 R hypothetical protein complement(759488..759640) Vibrio cholerae M66-2 7781024 YP_002812419.1 CDS gapA-2 NC_012580.1 759714 761243 D catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent; glyceraldehyde-3-phosphate dehydrogenase 759714..761243 Vibrio cholerae M66-2 7781025 YP_002812420.1 CDS VCM66_A0803 NC_012580.1 761359 761505 D hypothetical protein 761359..761505 Vibrio cholerae M66-2 7781026 YP_002812421.1 CDS VCM66_A0804 NC_012580.1 761457 761768 D hypothetical protein 761457..761768 Vibrio cholerae M66-2 7781027 YP_002812422.1 CDS VCM66_A0805 NC_012580.1 761817 762431 R hypothetical protein complement(761817..762431) Vibrio cholerae M66-2 7781028 YP_002812423.1 CDS VCM66_A0806 NC_012580.1 762539 763861 D uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH 762539..763861 Vibrio cholerae M66-2 7781029 YP_002812424.1 CDS VCM66_A0807 NC_012580.1 763904 764884 R GGDEF family protein complement(763904..764884) Vibrio cholerae M66-2 7781030 YP_002812425.1 CDS VCM66_A0808 NC_012580.1 765015 774806 R hypothetical protein complement(765015..774806) Vibrio cholerae M66-2 7781031 YP_002812426.1 CDS VCM66_A0809 NC_012580.1 775107 775892 R response regulator complement(775107..775892) Vibrio cholerae M66-2 7781032 YP_002812427.1 CDS VCM66_A0810 NC_012580.1 776052 777131 R hypothetical protein complement(776052..777131) Vibrio cholerae M66-2 7781033 YP_002812428.1 CDS VCM66_A0811 NC_012580.1 777132 778376 R hypothetical protein complement(777132..778376) Vibrio cholerae M66-2 7781034 YP_002812429.1 CDS VCM66_A0812 NC_012580.1 778381 779124 R hypothetical protein complement(778381..779124) Vibrio cholerae M66-2 7781035 YP_002812430.1 CDS VCM66_A0813 NC_012580.1 779117 780376 R hypothetical protein complement(779117..780376) Vibrio cholerae M66-2 7781036 YP_002812431.1 CDS VCM66_A0814 NC_012580.1 780364 781047 R ABC transporter ATP-binding protein complement(780364..781047) Vibrio cholerae M66-2 7781037 YP_002812432.1 CDS VCM66_A0815 NC_012580.1 781056 781727 R hypothetical protein complement(781056..781727) Vibrio cholerae M66-2 7781038 YP_002812433.1 CDS VCM66_A0816 NC_012580.1 781754 781888 D hypothetical protein 781754..781888 Vibrio cholerae M66-2 7781039 YP_002812434.1 CDS VCM66_A0817 NC_012580.1 781889 782032 D hypothetical protein 781889..782032 Vibrio cholerae M66-2 7781040 YP_002812435.1 CDS VCM66_A0818 NC_012580.1 782040 782963 R oxidoreductase, aldo/keto reductase 2 family complement(782040..782963) Vibrio cholerae M66-2 7781041 YP_002812436.1 CDS malS NC_012580.1 783255 785327 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase precursor 783255..785327 Vibrio cholerae M66-2 7781042 YP_002812437.1 CDS VCM66_A0820 NC_012580.1 785269 785502 D hypothetical protein 785269..785502 Vibrio cholerae M66-2 7781043 YP_002812438.1 CDS fadL-3 NC_012580.1 785862 787100 D long-chain fatty acid transport protein 785862..787100 Vibrio cholerae M66-2 7781044 YP_002812439.1 CDS VCM66_A0822 NC_012580.1 787116 789506 D putative lipase 787116..789506 Vibrio cholerae M66-2 7781045 YP_002812440.1 CDS VCM66_A0823 NC_012580.1 789867 791264 D methyl-accepting chemotaxis protein 789867..791264 Vibrio cholerae M66-2 7781046 YP_002812441.1 CDS hap NC_012580.1 791345 793174 R hemagglutinin/protease complement(791345..793174) Vibrio cholerae M66-2 7781047 YP_002812442.1 CDS VCM66_A0825 NC_012580.1 793160 793399 D hypothetical protein 793160..793399 Vibrio cholerae M66-2 7781048 YP_002812443.1 CDS ompW NC_012580.1 793595 794248 R receptor for colicin S4; outer membrane protein W complement(793595..794248) Vibrio cholerae M66-2 7781049 YP_002812444.1 CDS VCM66_A0827 NC_012580.1 794438 794671 D hypothetical protein 794438..794671 Vibrio cholerae M66-2 7781050 YP_002812445.1 CDS VCM66_A0828 NC_012580.1 795068 795166 R hypothetical protein complement(795068..795166) Vibrio cholerae M66-2 7781051 YP_002812446.1 CDS pbpG NC_012580.1 795202 796152 D specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 795202..796152 Vibrio cholerae M66-2 7781052 YP_002812447.1 CDS VCM66_A0830 NC_012580.1 796387 797808 D GntR family transcriptional regulator 796387..797808 Vibrio cholerae M66-2 7781053 YP_002812448.1 CDS cydA-2 NC_012580.1 797937 799529 D cytochrome d ubiquinol oxidase, subunit I 797937..799529 Vibrio cholerae M66-2 7781054 YP_002812449.1 CDS cydB-2 NC_012580.1 799542 800678 D cytochrome d ubiquinol oxidase, subunit II 799542..800678 Vibrio cholerae M66-2 7781055 YP_002812450.1 CDS VCM66_A0833 NC_012580.1 801500 801703 D hypothetical protein 801500..801703 Vibrio cholerae M66-2 7781056 YP_002812451.1 CDS dsdA NC_012580.1 801920 803245 R catalyzes the formation of pyruvate from serine; D-serine dehydratase complement(801920..803245) Vibrio cholerae M66-2 7781057 YP_002812452.1 CDS dsdC NC_012580.1 803453 804397 D regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 803453..804397 Vibrio cholerae M66-2 7781058 YP_002812453.1 CDS VCM66_A0836 NC_012580.1 804697 805773 D putative hydrolase 804697..805773 Vibrio cholerae M66-2 7781059 YP_002812454.1 CDS VCM66_A0837 NC_012580.1 805881 806042 D integrase-related protein 805881..806042 Vibrio cholerae M66-2 7781060 YP_002812455.1 CDS VCM66_A0838 NC_012580.1 806571 806726 R hypothetical protein complement(806571..806726) Vibrio cholerae M66-2 7781061 YP_002812456.1 CDS VCM66_A0839 NC_012580.1 806671 807051 D hypothetical protein 806671..807051 Vibrio cholerae M66-2 7781062 YP_002812457.1 CDS VCM66_A0840 NC_012580.1 807076 807471 D hypothetical protein 807076..807471 Vibrio cholerae M66-2 7781063 YP_002812458.1 CDS VCM66_A0841 NC_012580.1 807483 808547 D hypothetical protein 807483..808547 Vibrio cholerae M66-2 7781064 YP_002812459.1 CDS VCM66_A0842 NC_012580.1 808560 809669 D hypothetical protein 808560..809669 Vibrio cholerae M66-2 7781065 YP_002812460.1 CDS VCM66_A0843 NC_012580.1 809720 810781 D hypothetical protein 809720..810781 Vibrio cholerae M66-2 7781066 YP_002812461.1 CDS VCM66_A0844 NC_012580.1 810916 811089 R hypothetical protein complement(810916..811089) Vibrio cholerae M66-2 7781067 YP_002812462.1 CDS tdh NC_012580.1 811878 812909 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(811878..812909) Vibrio cholerae M66-2 7781068 YP_002812463.1 CDS kbl NC_012580.1 812912 814105 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase complement(812912..814105) Vibrio cholerae M66-2 7781069 YP_002812464.1 CDS VCM66_A0848 NC_012580.1 815262 816023 D transcriptional regulator, LuxR family 815262..816023 Vibrio cholerae M66-2 7781071 YP_002812465.1 CDS VCM66_A0849 NC_012580.1 816123 817061 D LysR family transcriptional regulator 816123..817061 Vibrio cholerae M66-2 7781072 YP_002812466.1 CDS VCM66_A0850 NC_012580.1 817055 817438 D glyoxylase I family protein 817055..817438 Vibrio cholerae M66-2 7781073 YP_002812467.1 CDS VCM66_A0851 NC_012580.1 817516 818928 R hypothetical protein complement(817516..818928) Vibrio cholerae M66-2 7781074 YP_002812468.1 CDS VCM66_A0852 NC_012580.1 819040 819438 R hypothetical protein complement(819040..819438) Vibrio cholerae M66-2 7781075 YP_002812469.1 CDS VCM66_A0853 NC_012580.1 819544 820053 R hypothetical protein complement(819544..820053) Vibrio cholerae M66-2 7781076 YP_002812470.1 CDS VCM66_A0854 NC_012580.1 820004 820750 R putative hydrolase complement(820004..820750) Vibrio cholerae M66-2 7781077 YP_002812471.1 CDS VCM66_A0855 NC_012580.1 820918 823863 D chemotactic transducer-related protein 820918..823863 Vibrio cholerae M66-2 7781078 YP_002812472.1 CDS zwf NC_012580.1 824207 825712 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 824207..825712 Vibrio cholerae M66-2 7781079 YP_002812473.1 CDS devB NC_012580.1 825709 826425 D devB protein 825709..826425 Vibrio cholerae M66-2 7781080 YP_002812474.1 CDS gnd NC_012580.1 826439 827887 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 826439..827887 Vibrio cholerae M66-2 7781081 YP_002812475.1 CDS VCM66_A0859 NC_012580.1 828043 828180 D hypothetical protein 828043..828180 Vibrio cholerae M66-2 7781082 YP_002812476.1 CDS VCM66_A0860 NC_012580.1 828448 829362 D hypothetical protein 828448..829362 Vibrio cholerae M66-2 7781083 YP_002812477.1 CDS VCM66_A0861 NC_012580.1 829356 829985 D hypothetical protein 829356..829985 Vibrio cholerae M66-2 7781084 YP_002812478.1 CDS VCM66_A0862 NC_012580.1 830018 830854 R hypothetical protein complement(830018..830854) Vibrio cholerae M66-2 7781085 YP_002812479.1 CDS VCM66_A0863 NC_012580.1 830990 832123 R hypothetical protein complement(830990..832123) Vibrio cholerae M66-2 7781086 YP_002812480.1 CDS VCM66_A0864 NC_012580.1 832142 833494 R permease complement(832142..833494) Vibrio cholerae M66-2 7781087 YP_002812481.1 CDS VCM66_A0865 NC_012580.1 833653 834792 R hypothetical protein complement(833653..834792) Vibrio cholerae M66-2 7781088 YP_002812482.1 CDS VCM66_A0866 NC_012580.1 834933 836669 R methyl-accepting chemotaxis protein complement(834933..836669) Vibrio cholerae M66-2 7781089 YP_002812483.1 CDS hutZ NC_012580.1 836976 837506 R heme-binding protein HutZ complement(836976..837506) Vibrio cholerae M66-2 7781090 YP_002812484.1 CDS hutX NC_012580.1 837531 838112 R hutX protein complement(837531..838112) Vibrio cholerae M66-2 7781091 YP_002812485.1 CDS hutW NC_012580.1 838058 839425 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(838058..839425) Vibrio cholerae M66-2 7781092 YP_002812486.1 CDS tonB1 NC_012580.1 839682 840431 D tonB1 protein 839682..840431 Vibrio cholerae M66-2 7781093 YP_002812487.1 CDS exbB1 NC_012580.1 840431 841117 D TonB system transport protein ExbB1 840431..841117 Vibrio cholerae M66-2 7781094 YP_002812488.1 CDS exbD1 NC_012580.1 841114 841530 D TonB system transport protein ExbD1 841114..841530 Vibrio cholerae M66-2 7781095 YP_002812489.1 CDS hutB NC_012580.1 841541 842374 D hemin ABC transporter, periplasmic hemin-binding protein HutB 841541..842374 Vibrio cholerae M66-2 7781096 YP_002812490.1 CDS hutC NC_012580.1 842386 843417 D hemin ABC transporter, permease protein 842386..843417 Vibrio cholerae M66-2 7781097 YP_002812491.1 CDS hmuV NC_012580.1 843486 844196 D with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 843486..844196 Vibrio cholerae M66-2 7781098 YP_002812492.1 CDS VCM66_A0876 NC_012580.1 844271 844369 R hypothetical protein complement(844271..844369) Vibrio cholerae M66-2 7781099 YP_002812493.1 CDS VCM66_A0877 NC_012580.1 844330 844815 R TetR family transcriptional regulator complement(844330..844815) Vibrio cholerae M66-2 7781100 YP_002812494.1 CDS VCM66_A0878 NC_012580.1 844784 844879 R hypothetical protein complement(844784..844879) Vibrio cholerae M66-2 7781101 YP_002812495.1 CDS VCM66_A0879 NC_012580.1 845314 845616 D hypothetical protein 845314..845616 Vibrio cholerae M66-2 7781102 YP_002812496.1 CDS VCM66_A0880 NC_012580.1 845819 846418 D hypothetical protein 845819..846418 Vibrio cholerae M66-2 7781103 YP_002812497.1 CDS VCM66_A0881 NC_012580.1 846479 847597 R putative Alkylated repair protein alkB complement(846479..847597) Vibrio cholerae M66-2 7781104 YP_002812498.1 CDS VCM66_A0882 NC_012580.1 847763 848371 D hypothetical protein 847763..848371 Vibrio cholerae M66-2 7781105 YP_002812499.1 CDS VCM66_A0883 NC_012580.1 848434 850392 D methyl-accepting chemotaxis protein 848434..850392 Vibrio cholerae M66-2 7781106 YP_002812500.1 CDS VCM66_A0884 NC_012580.1 850455 852443 R hypothetical protein complement(850455..852443) Vibrio cholerae M66-2 7781107 YP_002812501.1 CDS pyrC NC_012580.1 852811 853863 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 852811..853863 Vibrio cholerae M66-2 7781108 YP_002812502.1 CDS VCM66_A0886 NC_012580.1 853927 854970 R AraC family transcriptional regulator complement(853927..854970) Vibrio cholerae M66-2 7781109 YP_002812503.1 CDS VCM66_A0887 NC_012580.1 855135 855485 D hypothetical protein 855135..855485 Vibrio cholerae M66-2 7781110 YP_002812504.1 CDS VCM66_A0888 NC_012580.1 855482 855991 D hypothetical protein 855482..855991 Vibrio cholerae M66-2 7781111 YP_002812505.1 CDS rumB NC_012580.1 856058 857185 R RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase complement(856058..857185) Vibrio cholerae M66-2 7781112 YP_002812506.1 CDS VCM66_A0890 NC_012580.1 857350 858375 R hypothetical protein complement(857350..858375) Vibrio cholerae M66-2 7781113 YP_002812507.1 CDS VCM66_A0891 NC_012580.1 858398 859780 R hypothetical protein complement(858398..859780) Vibrio cholerae M66-2 7781114 YP_002812508.1 CDS VCM66_A0892 NC_012580.1 859766 859903 D hypothetical protein 859766..859903 Vibrio cholerae M66-2 7781115 YP_002812509.1 CDS VCM66_A0893 NC_012580.1 860129 860341 D cold shock domain family protein 860129..860341 Vibrio cholerae M66-2 7781116 YP_002812510.1 CDS VCM66_A0894 NC_012580.1 860439 860540 R hypothetical protein complement(860439..860540) Vibrio cholerae M66-2 7781117 YP_002812511.1 CDS VCM66_A0895 NC_012580.1 860906 861262 D hypothetical protein 860906..861262 Vibrio cholerae M66-2 7781118 YP_002812512.1 CDS VCM66_A0896 NC_012580.1 861474 862412 D hypothetical protein 861474..862412 Vibrio cholerae M66-2 7781119 YP_002812513.1 CDS VCM66_A0897 NC_012580.1 862401 863192 R AraC family transcriptional regulator complement(862401..863192) Vibrio cholerae M66-2 7781120 YP_002812514.1 CDS VCM66_A0898 NC_012580.1 863166 864191 D hypothetical protein 863166..864191 Vibrio cholerae M66-2 7781121 YP_002812515.1 CDS VCM66_A0899 NC_012580.1 864310 865275 D sensory box/GGDEF family protein 864310..865275 Vibrio cholerae M66-2 7781122 YP_002812516.1 CDS VCM66_A0900 NC_012580.1 865427 866188 D transcriptional regulator, DeoR family 865427..866188 Vibrio cholerae M66-2 7781123 YP_002812517.1 CDS VCM66_A0901 NC_012580.1 866352 866840 D acyl-CoA thioester hydrolase-related protein 866352..866840 Vibrio cholerae M66-2 7781124 YP_002812518.1 CDS VCM66_A0902 NC_012580.1 866924 867202 D hypothetical protein 866924..867202 Vibrio cholerae M66-2 7781125 YP_002812519.1 CDS malG NC_012580.1 867525 868415 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(867525..868415) Vibrio cholerae M66-2 7781126 YP_002812520.1 CDS malF NC_012580.1 868427 870001 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(868427..870001) Vibrio cholerae M66-2 7781127 YP_002812521.1 CDS malE NC_012580.1 870076 871263 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(870076..871263) Vibrio cholerae M66-2 7781128 YP_002812522.1 CDS malK NC_012580.1 871930 873051 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 871930..873051 Vibrio cholerae M66-2 7781129 YP_002812523.1 CDS speG NC_012580.1 873274 873795 D spermidine n1-acetyltransferase 873274..873795 Vibrio cholerae M66-2 7781130 YP_002812524.1 CDS VCM66_A0908 NC_012580.1 873800 874045 D hypothetical protein 873800..874045 Vibrio cholerae M66-2 7781131 YP_002812525.1 CDS VCM66_A0909 NC_012580.1 874183 874800 R SM-20-related protein complement(874183..874800) Vibrio cholerae M66-2 7781132 YP_002812526.1 CDS VCM66_A0910 NC_012580.1 874919 875047 R hypothetical protein complement(874919..875047) Vibrio cholerae M66-2 7781133 YP_002812527.1 CDS VCM66_A0911 NC_012580.1 875007 875327 D hypothetical protein 875007..875327 Vibrio cholerae M66-2 7781134 YP_002812528.1 CDS VCM66_A0912 NC_012580.1 875494 876168 R transcriptional regulator, LuxR family complement(875494..876168) Vibrio cholerae M66-2 7781135 YP_002812529.1 CDS ppiC NC_012580.1 876746 877024 R peptidyl-prolyl cis-trans isomerase C complement(876746..877024) Vibrio cholerae M66-2 7781136 YP_002812530.1 CDS VCM66_A0914 NC_012580.1 877199 878119 D putative chemotaxis protein CheV 877199..878119 Vibrio cholerae M66-2 7781137 YP_002812531.1 CDS VCM66_A0915 NC_012580.1 878195 878719 R transcriptional regulator, MarR family complement(878195..878719) Vibrio cholerae M66-2 7781138 YP_002812532.1 CDS VCM66_A0916 NC_012580.1 878888 879907 D GGDEF family protein 878888..879907 Vibrio cholerae M66-2 7781139 YP_002812533.1 CDS VCM66_A0917 NC_012580.1 880026 880634 R Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase complement(880026..880634) Vibrio cholerae M66-2 7781140 YP_002812534.1 CDS VCM66_A0918 NC_012580.1 880753 882270 D hypothetical protein 880753..882270 Vibrio cholerae M66-2 7781141 YP_002812535.1 CDS VCM66_A0919 NC_012580.1 882373 882531 R hypothetical protein complement(882373..882531) Vibrio cholerae M66-2 7781142 YP_002812536.1 CDS VCM66_A0920 NC_012580.1 882550 883923 R GGDEF family protein complement(882550..883923) Vibrio cholerae M66-2 7781143 YP_002812537.1 CDS VCM66_A0921 NC_012580.1 884265 884873 D hypothetical protein 884265..884873 Vibrio cholerae M66-2 7781144 YP_002812538.1 CDS VCM66_A0922 NC_012580.1 885160 886368 D hypothetical protein 885160..886368 Vibrio cholerae M66-2 7781145 YP_002812539.1 CDS VCM66_A0923 NC_012580.1 886393 887316 R hypothetical protein complement(886393..887316) Vibrio cholerae M66-2 7781146 YP_002812540.1 CDS VCM66_A0924 NC_012580.1 887417 888322 D putative glycine cleavage operon activator 887417..888322 Vibrio cholerae M66-2 7781147 YP_002812541.1 CDS VCM66_A0925 NC_012580.1 888474 889664 D GGDEF family protein 888474..889664 Vibrio cholerae M66-2 7781148 YP_002812542.1 CDS VCM66_A0926 NC_012580.1 889667 889963 R hypothetical protein complement(889667..889963) Vibrio cholerae M66-2 7781149 YP_002812543.1 CDS VCM66_A0927 NC_012580.1 889926 890030 R hypothetical protein complement(889926..890030) Vibrio cholerae M66-2 7781150 YP_002812544.1 CDS VCM66_A0928 NC_012580.1 890050 890145 D hypothetical protein 890050..890145 Vibrio cholerae M66-2 7781151 YP_002812545.1 CDS VCM66_A0929 NC_012580.1 890138 890986 D pirin-related protein 890138..890986 Vibrio cholerae M66-2 7781152 YP_002812546.1 CDS VCM66_A0930 NC_012580.1 891124 891438 R hypothetical protein complement(891124..891438) Vibrio cholerae M66-2 7781153 YP_002812547.1 CDS VCM66_A0931 NC_012580.1 891950 892390 D hypothetical protein 891950..892390 Vibrio cholerae M66-2 7781154 YP_002812548.1 CDS VCM66_A0932 NC_012580.1 892399 893703 R hypothetical protein complement(892399..893703) Vibrio cholerae M66-2 7781155 YP_002812549.1 CDS VCM66_A0933 NC_012580.1 893760 893933 D hypothetical protein 893760..893933 Vibrio cholerae M66-2 7781156 YP_002812550.1 CDS VCM66_A0934 NC_012580.1 893966 895651 R methyl-accepting chemotaxis protein complement(893966..895651) Vibrio cholerae M66-2 7781157 YP_002812551.1 CDS VCM66_A0935 NC_012580.1 895866 898226 R ATP-dependent protease LA-related protein complement(895866..898226) Vibrio cholerae M66-2 7781158 YP_002812552.1 CDS VCM66_A0936 NC_012580.1 898430 898924 D hypothetical protein 898430..898924 Vibrio cholerae M66-2 7781159 YP_002812553.1 CDS VCM66_A0937 NC_012580.1 898953 900572 D ABC transporter ATP-binding protein 898953..900572 Vibrio cholerae M66-2 7781160 YP_002812554.1 CDS VCM66_A0938 NC_012580.1 900739 901470 R putative amino acid ABC transporter, periplasmic amino acid-binding protein complement(900739..901470) Vibrio cholerae M66-2 7781161 YP_002812555.1 CDS VCM66_A0939 NC_012580.1 901490 903037 R methyl-accepting chemotaxis protein complement(901490..903037) Vibrio cholerae M66-2 7781162 YP_002812556.1 CDS VCM66_A0940 NC_012580.1 903168 903911 R hypothetical protein complement(903168..903911) Vibrio cholerae M66-2 7781163 YP_002812557.1 CDS VCM66_A0941 NC_012580.1 904065 904964 R LysR family transcriptional regulator complement(904065..904964) Vibrio cholerae M66-2 7781164 YP_002812558.1 CDS VCM66_A0942 NC_012580.1 905116 906864 D putative L-lactate permease 905116..906864 Vibrio cholerae M66-2 7781165 YP_002812559.1 CDS lldD NC_012580.1 906987 908123 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 906987..908123 Vibrio cholerae M66-2 7781166 YP_002812560.1 CDS VCM66_A0944 NC_012580.1 908221 911100 D oxidoreductase/iron-sulfur cluster-binding protein 908221..911100 Vibrio cholerae M66-2 7781167 YP_002812561.1 CDS VCM66_A0945 NC_012580.1 911184 912017 R hypothetical protein complement(911184..912017) Vibrio cholerae M66-2 7781168 YP_002812562.1 CDS ppsA NC_012580.1 912152 914563 D catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 912152..914563 Vibrio cholerae M66-2 7781169 YP_002812563.1 CDS VCM66_A0947 NC_012580.1 914746 916302 D methyl-accepting chemotaxis protein 914746..916302 Vibrio cholerae M66-2 7781170 YP_002812564.1 CDS VCM66_A0948 NC_012580.1 916660 917994 D hypothetical protein 916660..917994 Vibrio cholerae M66-2 7781171 YP_002812565.1 CDS VCM66_A0949 NC_012580.1 918073 919359 R ATP-dependent RNA helicase, DEAD box family complement(918073..919359) Vibrio cholerae M66-2 7781172 YP_002812566.1 CDS VCM66_A0950 NC_012580.1 919451 920377 R LysR family transcriptional regulator complement(919451..920377) Vibrio cholerae M66-2 7781173 YP_002812567.1 CDS grx2 NC_012580.1 920498 921154 D cofactor involved in the reduction of disulfides; glutaredoxin 2 920498..921154 Vibrio cholerae M66-2 7781174 YP_002812568.1 CDS nemA NC_012580.1 921164 922267 D N-ethylmaleimide reductase 921164..922267 Vibrio cholerae M66-2 7781175 YP_002812569.1 CDS VCM66_A0953 NC_012580.1 922388 923368 R hypothetical protein complement(922388..923368) Vibrio cholerae M66-2 7781176 YP_002812570.1 CDS VCM66_A0954 NC_012580.1 923501 923602 D hypothetical protein 923501..923602 Vibrio cholerae M66-2 7781177 YP_002812571.1 CDS VCM66_A0955 NC_012580.1 923725 925584 D ABC transporter ATP-binding protein 923725..925584 Vibrio cholerae M66-2 7781178 YP_002812572.1 CDS VCM66_A0956 NC_012580.1 925715 926440 D hypothetical protein 925715..926440 Vibrio cholerae M66-2 7781179 YP_002812573.1 CDS VCM66_A0957 NC_012580.1 926530 927573 R NADH-dependent flavin oxidoreductase, Oye family complement(926530..927573) Vibrio cholerae M66-2 7781180 YP_002812574.1 CDS VCM66_A0958 NC_012580.1 927723 928298 D TetR family transcriptional regulator 927723..928298 Vibrio cholerae M66-2 7781181 YP_002812575.1 CDS VCM66_A0959 NC_012580.1 928370 928999 R hypothetical protein complement(928370..928999) Vibrio cholerae M66-2 7781182 YP_002812576.1 CDS VCM66_A0960 NC_012580.1 929200 930033 D AraC family transcriptional regulator 929200..930033 Vibrio cholerae M66-2 7781183 YP_002812577.1 CDS VCM66_A0961 NC_012580.1 930185 930904 D AzlC family protein 930185..930904 Vibrio cholerae M66-2 7781184 YP_002812578.1 CDS VCM66_A0962 NC_012580.1 930901 931218 D hypothetical protein 930901..931218 Vibrio cholerae M66-2 7781185 YP_002812579.1 CDS VCM66_A0963 NC_012580.1 931270 931884 R hypothetical protein complement(931270..931884) Vibrio cholerae M66-2 7781186 YP_002812580.1 CDS VCM66_A0964 NC_012580.1 932000 932458 R transcriptional regulator, MarR family complement(932000..932458) Vibrio cholerae M66-2 7781187 YP_002812581.1 CDS VCM66_A0965 NC_012580.1 932555 932992 D putative organic hydroperoxide resistance protein 932555..932992 Vibrio cholerae M66-2 7781188 YP_002812582.1 CDS VCM66_A0966 NC_012580.1 933006 933104 R hypothetical protein complement(933006..933104) Vibrio cholerae M66-2 7781189 YP_002812583.1 CDS VCM66_A0967 NC_012580.1 933248 934243 D putative outer membrane protein 933248..934243 Vibrio cholerae M66-2 7781190 YP_002812584.1 CDS VCM66_A0968 NC_012580.1 934269 934388 D hypothetical protein 934269..934388 Vibrio cholerae M66-2 7781191 YP_002812585.1 CDS VCM66_A0969 NC_012580.1 934404 935300 D hypothetical protein 934404..935300 Vibrio cholerae M66-2 7781192 YP_002812586.1 CDS VCM66_A0970 NC_012580.1 935327 935965 D glutaredoxin-related protein 935327..935965 Vibrio cholerae M66-2 7781193 YP_002812587.1 CDS VCM66_A0971 NC_012580.1 936179 936646 R hypothetical protein complement(936179..936646) Vibrio cholerae M66-2 7781194 YP_002812588.1 CDS VCM66_A0972 NC_012580.1 936643 937374 R hypothetical protein complement(936643..937374) Vibrio cholerae M66-2 7781195 YP_002812589.1 CDS VCM66_A0973 NC_012580.1 937537 937638 R hypothetical protein complement(937537..937638) Vibrio cholerae M66-2 7781196 YP_002812590.1 CDS nhaD NC_012580.1 937766 939199 D Na+/H+ antiporter 937766..939199 Vibrio cholerae M66-2 7781197 YP_002812591.1 CDS VCM66_A0975 NC_012580.1 939265 939666 R hypothetical protein complement(939265..939666) Vibrio cholerae M66-2 7781198 YP_002812592.1 CDS ogt NC_012580.1 939677 940150 R methylated-DNA--protein-cysteine S-methyltransferase complement(939677..940150) Vibrio cholerae M66-2 7781199 YP_002812593.1 CDS ada NC_012580.1 940151 941509 R ada regulatory protein complement(940151..941509) Vibrio cholerae M66-2 7781200 YP_002812594.1 CDS VCM66_A0978 NC_012580.1 941765 942211 D hypothetical protein 941765..942211 Vibrio cholerae M66-2 7781201 YP_002812595.1 CDS VCM66_A0979 NC_012580.1 942288 943208 R LysR family transcriptional regulator complement(942288..943208) Vibrio cholerae M66-2 7781202 YP_002812596.1 CDS VCM66_A0980 NC_012580.1 943323 943682 D hypothetical protein 943323..943682 Vibrio cholerae M66-2 7781203 YP_002812597.1 CDS VCM66_A0981 NC_012580.1 943728 945752 D hypothetical protein 943728..945752 Vibrio cholerae M66-2 7781204 YP_002812598.1 CDS VCM66_A0982 NC_012580.1 945879 946220 R hypothetical protein complement(945879..946220) Vibrio cholerae M66-2 7781205 YP_002812599.1 CDS nagB NC_012580.1 946495 947295 D catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 946495..947295 Vibrio cholerae M66-2 7781206 YP_002812600.1 CDS VCM66_A0984 NC_012580.1 947426 948583 R hypothetical protein complement(947426..948583) Vibrio cholerae M66-2 7781207 YP_002812601.1 CDS VCM66_A0985 NC_012580.1 948736 949572 R putative maltose operon periplasmic protein complement(948736..949572) Vibrio cholerae M66-2 7781208 YP_002812602.1 CDS lamB NC_012580.1 949777 951027 R porin involved in the transport of maltose and maltodextrins; maltoporin complement(949777..951027) Vibrio cholerae M66-2 7781209 YP_002812603.1 CDS glgX NC_012580.1 951447 953417 D glycogen operon protein GlgX 951447..953417 Vibrio cholerae M66-2 7781210 YP_002812604.1 CDS VCM66_A0988 NC_012580.1 953552 953803 D hypothetical protein 953552..953803 Vibrio cholerae M66-2 7781211 YP_002812605.1 CDS VCM66_A0989 NC_012580.1 954263 955894 D methyl-accepting chemotaxis protein 954263..955894 Vibrio cholerae M66-2 7781212 YP_002812606.1 CDS VCM66_A0990 NC_012580.1 956009 956416 R hypothetical protein complement(956009..956416) Vibrio cholerae M66-2 7781213 YP_002812607.1 CDS VCM66_A0991 NC_012580.1 956684 958060 R putative extracellular solute-binding protein complement(956684..958060) Vibrio cholerae M66-2 7781214 YP_002812608.1 CDS VCM66_A0992 NC_012580.1 958069 960069 R methyl-accepting chemotaxis protein complement(958069..960069) Vibrio cholerae M66-2 7781215 YP_002812609.1 CDS VCM66_A0993 NC_012580.1 960183 960500 D hypothetical protein 960183..960500 Vibrio cholerae M66-2 7781216 YP_002812610.1 CDS VCM66_A0994 NC_012580.1 960594 961760 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(960594..961760) Vibrio cholerae M66-2 7781217 YP_002812611.1 CDS VCM66_A0995 NC_012580.1 961948 962667 D amino acid ABC transporter ATP-binding protein 961948..962667 Vibrio cholerae M66-2 7781218 YP_002812612.1 CDS VCM66_A0996 NC_012580.1 962664 963464 D amino acid ABC transporter permease 962664..963464 Vibrio cholerae M66-2 7781219 YP_002812613.1 CDS VCM66_A0997 NC_012580.1 963500 964336 D amino acid ABC transporter substrate-binding protein 963500..964336 Vibrio cholerae M66-2 7781220 YP_002812614.1 CDS VCM66_A0998 NC_012580.1 964337 965233 D amino acid ABC transporter permease 964337..965233 Vibrio cholerae M66-2 7781221 YP_002812615.1 CDS VCM66_A0999 NC_012580.1 965346 967049 D putative phosphomannomutase 965346..967049 Vibrio cholerae M66-2 7781222 YP_002812616.1 CDS VCM66_A1000 NC_012580.1 967108 967509 R Ccm2-related protein complement(967108..967509) Vibrio cholerae M66-2 7781223 YP_002812617.1 CDS tagE-2 NC_012580.1 967419 968360 R tagE protein complement(967419..968360) Vibrio cholerae M66-2 7781224 YP_002812618.1 CDS VCM66_A1002 NC_012580.1 968661 968804 D hypothetical protein 968661..968804 Vibrio cholerae M66-2 7781225 YP_002812619.1 CDS mtlA NC_012580.1 968943 970892 D PTS system, mannitol-specific IIABC component 968943..970892 Vibrio cholerae M66-2 7781226 YP_002812620.1 CDS mtlD NC_012580.1 970993 972147 D mannitol-1-phosphate 5-dehydrogenase 970993..972147 Vibrio cholerae M66-2 7781227 YP_002812621.1 CDS mtlR NC_012580.1 972196 972777 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 972196..972777 Vibrio cholerae M66-2 7781228 YP_002812622.1 CDS VCM66_A1006 NC_012580.1 972891 973826 D oxidoreductase, Gfo/Idh/MocA family 972891..973826 Vibrio cholerae M66-2 7781229 YP_002812623.1 CDS VCM66_A1007 NC_012580.1 973927 974805 R hypothetical protein complement(973927..974805) Vibrio cholerae M66-2 7781230 YP_002812624.1 CDS VCM66_A1008 NC_012580.1 974939 975862 D hypothetical protein 974939..975862 Vibrio cholerae M66-2 7781231 YP_002812625.1 CDS VCM66_A1009 NC_012580.1 975859 976290 R hypothetical protein complement(975859..976290) Vibrio cholerae M66-2 7781232 YP_002812626.1 CDS VCM66_A1010 NC_012580.1 976366 977088 R hypothetical protein complement(976366..977088) Vibrio cholerae M66-2 7781233 YP_002812627.1 CDS VCM66_A1011 NC_012580.1 977270 977770 R hypothetical protein complement(977270..977770) Vibrio cholerae M66-2 7781234 YP_002812628.1 CDS VCM66_A1012 NC_012580.1 977792 978430 R hypothetical protein complement(977792..978430) Vibrio cholerae M66-2 7781235 YP_002812629.1 CDS VCM66_A1013 NC_012580.1 978530 979453 D LysR family transcriptional regulator 978530..979453 Vibrio cholerae M66-2 7781236 YP_002812630.1 CDS VCM66_A1014 NC_012580.1 979496 981808 R methyl-accepting chemotaxis protein complement(979496..981808) Vibrio cholerae M66-2 7781237 YP_002812631.1 CDS VCM66_A1015 NC_012580.1 982198 982917 R oxidoreductase, short-chain dehydrogenase/reductase family complement(982198..982917) Vibrio cholerae M66-2 7781238 YP_002812632.1 CDS VCM66_A1016 NC_012580.1 983065 983970 D LysR family transcriptional regulator 983065..983970 Vibrio cholerae M66-2 7781239 YP_002812633.1 CDS VCM66_A1017 NC_012580.1 984064 984681 D hypothetical protein 984064..984681 Vibrio cholerae M66-2 7781240 YP_002812634.1 CDS ribB NC_012580.1 984746 985402 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(984746..985402) Vibrio cholerae M66-2 7781241 YP_002812635.1 CDS VCM66_A1019 NC_012580.1 985709 985843 D sensor histidine kinase 985709..985843 Vibrio cholerae M66-2 7781242 YP_002812636.1 CDS potE NC_012580.1 985861 987180 R catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter complement(985861..987180) Vibrio cholerae M66-2 7781243 YP_002812637.1 CDS speF NC_012580.1 987248 989410 R ornithine decarboxylase complement(987248..989410) Vibrio cholerae M66-2 7781244 YP_002812638.1 CDS VCM66_A1022 NC_012580.1 989551 989673 D hypothetical protein 989551..989673 Vibrio cholerae M66-2 7781245 YP_002812639.1 CDS VCM66_A1023 NC_012580.1 989750 989872 R hypothetical protein complement(989750..989872) Vibrio cholerae M66-2 7781246 YP_002812640.1 CDS VCM66_A1024 NC_012580.1 990164 990403 R hypothetical protein complement(990164..990403) Vibrio cholerae M66-2 7781247 YP_002812641.1 CDS VCM66_A1025 NC_012580.1 990393 991835 R aldehyde dehydrogenase complement(990393..991835) Vibrio cholerae M66-2 7781248 YP_002812642.1 CDS VCM66_A1026 NC_012580.1 992008 992490 R transcriptional regulator, AsnC family complement(992008..992490) Vibrio cholerae M66-2 7781249 YP_002812643.1 CDS VCM66_A1027 NC_012580.1 992688 994607 R methyl-accepting chemotaxis protein complement(992688..994607) Vibrio cholerae M66-2 7781250 YP_002812644.1 CDS VCM66_A1028 NC_012580.1 994937 995158 R hypothetical protein complement(994937..995158) Vibrio cholerae M66-2 7781251 YP_002812645.1 CDS putP NC_012580.1 995342 996832 R sodium/proline symporter complement(995342..996832) Vibrio cholerae M66-2 7781252 YP_002812646.1 CDS VCM66_A1030 NC_012580.1 996905 997603 R hypothetical protein complement(996905..997603) Vibrio cholerae M66-2 7781253 YP_002812647.1 CDS putA NC_012580.1 997625 1000744 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(997625..1000744) Vibrio cholerae M66-2 7781254 YP_002812648.1 CDS VCM66_A1032 NC_012580.1 1001084 1001947 R AraC family transcriptional regulator complement(1001084..1001947) Vibrio cholerae M66-2 7781255 YP_002812649.1 CDS VCM66_A1033 NC_012580.1 1002306 1003445 D hypothetical protein 1002306..1003445 Vibrio cholerae M66-2 7781256 YP_002812650.1 CDS VCM66_A1034 NC_012580.1 1003412 1003537 D hypothetical protein 1003412..1003537 Vibrio cholerae M66-2 7781257 YP_002812651.1 CDS VCM66_A1035 NC_012580.1 1003605 1005422 D hypothetical protein 1003605..1005422 Vibrio cholerae M66-2 7781258 YP_002812652.1 CDS VCM66_A1036 NC_012580.1 1005522 1006481 D transcriptional regulator, LuxR family 1005522..1006481 Vibrio cholerae M66-2 7781259 YP_002812653.1 CDS pdxH NC_012580.1 1006510 1007145 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(1006510..1007145) Vibrio cholerae M66-2 7781260 YP_002812654.1 CDS VCM66_A1038 NC_012580.1 1007315 1008760 D secretion protein, HlyD family 1007315..1008760 Vibrio cholerae M66-2 7781261 YP_002812655.1 CDS VCM66_A1039 NC_012580.1 1008769 1009431 D hypothetical protein 1008769..1009431 Vibrio cholerae M66-2 7781262 YP_002812656.1 CDS VCM66_A1040 NC_012580.1 1009437 1011347 D putative Signaling protein ykoW 1009437..1011347 Vibrio cholerae M66-2 7781263 YP_002812657.1 CDS VCM66_A1041 NC_012580.1 1011362 1013476 D toxin secretion ATP-binding protein 1011362..1013476 Vibrio cholerae M66-2 7781264 YP_002812658.1 CDS VCM66_A1042 NC_012580.1 1013611 1015281 R hypothetical protein complement(1013611..1015281) Vibrio cholerae M66-2 7781265 YP_002812659.1 CDS VCM66_A1043 NC_012580.1 1015540 1017246 R response regulator complement(1015540..1017246) Vibrio cholerae M66-2 7781266 YP_002812660.1 CDS VCM66_A1044 NC_012580.1 1017270 1017569 R putative anti-sigma F factor antagonist complement(1017270..1017569) Vibrio cholerae M66-2 7781267 YP_002812661.1 CDS VCM66_A1045 NC_012580.1 1017579 1018733 R methyl-accepting chemotaxis protein complement(1017579..1018733) Vibrio cholerae M66-2 7781268 YP_002812662.1 CDS cheB-3 NC_012580.1 1018776 1019816 R protein-glutamate methylesterase CheB complement(1018776..1019816) Vibrio cholerae M66-2 7781269 YP_002812663.1 CDS VCM66_A1047 NC_012580.1 1019813 1020514 R catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors; chemoreceptor glutamine deamidase CheD complement(1019813..1020514) Vibrio cholerae M66-2 7781270 YP_002812664.1 CDS cheR-3 NC_012580.1 1020453 1021283 R chemotaxis protein methyltransferase CheR complement(1020453..1021283) Vibrio cholerae M66-2 7781271 YP_002812665.1 CDS VCM66_A1049 NC_012580.1 1021298 1023334 R methyl-accepting chemotaxis protein complement(1021298..1023334) Vibrio cholerae M66-2 7781272 YP_002812666.1 CDS cheW-2 NC_012580.1 1023348 1023809 R purine-binding chemotaxis protein CheW complement(1023348..1023809) Vibrio cholerae M66-2 7781273 YP_002812667.1 CDS cheW-3 NC_012580.1 1023806 1024333 R purine-binding chemotaxis protein CheW complement(1023806..1024333) Vibrio cholerae M66-2 7781274 YP_002812668.1 CDS cheA-3 NC_012580.1 1024342 1026504 R chemotaxis protein CheA complement(1024342..1026504) Vibrio cholerae M66-2 7781275 YP_002812669.1 CDS cheY-4 NC_012580.1 1026553 1026930 R chemotaxis protein CheY complement(1026553..1026930) Vibrio cholerae M66-2 7781276 YP_002812670.1 CDS VCM66_A1054 NC_012580.1 1026923 1027228 R hypothetical protein complement(1026923..1027228) Vibrio cholerae M66-2 7781277 YP_002812671.1 CDS VCM66_A1055 NC_012580.1 1027426 1028991 D ABC transporter substrate-binding protein 1027426..1028991 Vibrio cholerae M66-2 7781278 YP_002812672.1 CDS VCM66_A1056 NC_012580.1 1028984 1029940 D ABC transporter permease 1028984..1029940 Vibrio cholerae M66-2 7781279 YP_002812673.1 CDS VCM66_A1057 NC_012580.1 1029921 1030733 D ABC transporter permease 1029921..1030733 Vibrio cholerae M66-2 7781280 YP_002812674.1 CDS VCM66_A1058 NC_012580.1 1030652 1032112 D ABC transporter ATP-binding protein 1030652..1032112 Vibrio cholerae M66-2 7781281 YP_002812675.1 CDS VCM66_A1059 NC_012580.1 1032367 1034019 D hypothetical protein 1032367..1034019 Vibrio cholerae M66-2 7781282 YP_002812676.1 CDS VCM66_A1060 NC_012580.1 1034060 1034158 D hypothetical protein 1034060..1034158 Vibrio cholerae M66-2 7781283 YP_002812677.1 CDS VCM66_A1061 NC_012580.1 1034171 1035586 R sensor histidine kinase complement(1034171..1035586) Vibrio cholerae M66-2 7781284 YP_002812678.1 CDS VCM66_A1062 NC_012580.1 1035576 1036232 R DNA-binding response regulator complement(1035576..1036232) Vibrio cholerae M66-2 7781285 YP_002812679.1 CDS VCM66_A1063 NC_012580.1 1036237 1036869 R hypothetical protein complement(1036237..1036869) Vibrio cholerae M66-2 7781286 YP_002812680.1 CDS VCM66_A1064 NC_012580.1 1036897 1037694 R short chain dehydrogenase complement(1036897..1037694) Vibrio cholerae M66-2 7781287 YP_002812681.1 CDS VCM66_A1065 NC_012580.1 1037704 1038414 R hypothetical protein complement(1037704..1038414) Vibrio cholerae M66-2 7781288 YP_002812682.1 CDS VCM66_A1066 NC_012580.1 1038430 1039953 R putative long-chain-fatty-acid--CoA ligase complement(1038430..1039953) Vibrio cholerae M66-2 7781289 YP_002812683.1 CDS VCM66_A1067 NC_012580.1 1039964 1040566 R thermostable hemolysin complement(1039964..1040566) Vibrio cholerae M66-2 7781290 YP_002812684.1 CDS VCM66_A1068 NC_012580.1 1040740 1042866 R hypothetical protein complement(1040740..1042866) Vibrio cholerae M66-2 7781291 YP_002812685.1 CDS VCM66_A1069 NC_012580.1 1042994 1044025 D spermidine/putrescine ABC transporter substrate-binding protein 1042994..1044025 Vibrio cholerae M66-2 7781292 YP_002812686.1 CDS VCM66_A1070 NC_012580.1 1044085 1045056 R ParB family protein complement(1044085..1045056) Vibrio cholerae M66-2 7781293 YP_002812687.1 CDS VCM66_A1071 NC_012580.1 1045064 1046287 R ParA family protein complement(1045064..1046287) Vibrio cholerae M66-2 7781294 VCM66_tRNAALA1 tRNA VCM66_tRNAALA1 NC_012578.1 55385 55460 D tRNA-Ala 55385..55460 Vibrio cholerae M66-2 7773968 VCM66_tRNAASP1 tRNA VCM66_tRNAASP1 NC_012578.1 58906 58982 D tRNA-Asp 58906..58982 Vibrio cholerae M66-2 7773982 VCM66_tRNATRP1 tRNA VCM66_tRNATRP1 NC_012578.1 59012 59088 D tRNA-Trp 59012..59088 Vibrio cholerae M66-2 7774007 VCM66_tRNAGLU2 tRNA VCM66_tRNAGLU2 NC_012578.1 152634 152709 D tRNA-Glu 152634..152709 Vibrio cholerae M66-2 7773969 VCM66_tRNALYS1 tRNA VCM66_tRNALYS1 NC_012578.1 152729 152803 D tRNA-Lys 152729..152803 Vibrio cholerae M66-2 7774019 VCM66_tRNAVAL1 tRNA VCM66_tRNAVAL1 NC_012578.1 152834 152909 D tRNA-Val 152834..152909 Vibrio cholerae M66-2 7774044 VCM66_tRNAALA2 tRNA VCM66_tRNAALA2 NC_012578.1 152915 152990 D tRNA-Ala 152915..152990 Vibrio cholerae M66-2 7774079 VCM66_tRNASER1 tRNA VCM66_tRNASER1 NC_012578.1 156458 156548 D tRNA-Ser 156458..156548 Vibrio cholerae M66-2 7773983 VCM66_tRNAARG1 tRNA VCM66_tRNAARG1 NC_012578.1 167439 167515 D tRNA-Arg 167439..167515 Vibrio cholerae M66-2 7771463 VCM66_tRNAHIS1 tRNA VCM66_tRNAHIS1 NC_012578.1 167551 167626 D tRNA-His 167551..167626 Vibrio cholerae M66-2 7773995 VCM66_tRNAPRO1 tRNA VCM66_tRNAPRO1 NC_012578.1 167688 167764 D tRNA-Pro 167688..167764 Vibrio cholerae M66-2 7774028 VCM66_tRNAHIS2 tRNA VCM66_tRNAHIS2 NC_012578.1 167835 167910 D tRNA-His 167835..167910 Vibrio cholerae M66-2 7774058 VCM66_tRNAPRO2 tRNA VCM66_tRNAPRO2 NC_012578.1 167972 168048 D tRNA-Pro 167972..168048 Vibrio cholerae M66-2 7774029 VCM66_tRNAILE1 tRNA VCM66_tRNAILE1 NC_012578.1 310471 310547 D tRNA-Ile 310471..310547 Vibrio cholerae M66-2 7773970 VCM66_tRNAALA3 tRNA VCM66_tRNAALA3 NC_012578.1 310556 310631 D tRNA-Ala 310556..310631 Vibrio cholerae M66-2 7774030 VCM66_tRNAASP2 tRNA VCM66_tRNAASP2 NC_012578.1 314076 314152 D tRNA-Asp 314076..314152 Vibrio cholerae M66-2 7773984 VCM66_tRNATHR1 tRNA VCM66_tRNATHR1 NC_012578.1 319545 319620 D tRNA-Thr 319545..319620 Vibrio cholerae M66-2 7771594 VCM66_tRNATYR1 tRNA VCM66_tRNATYR1 NC_012578.1 319656 319740 D tRNA-Tyr 319656..319740 Vibrio cholerae M66-2 7774067 VCM66_tRNAGLY1 tRNA VCM66_tRNAGLY1 NC_012578.1 319776 319850 D tRNA-Gly 319776..319850 Vibrio cholerae M66-2 7774074 VCM66_tRNATHR2 tRNA VCM66_tRNATHR2 NC_012578.1 319864 319939 D tRNA-Thr 319864..319939 Vibrio cholerae M66-2 7774021 VCM66_tRNAGLY2 tRNA VCM66_tRNAGLY2 NC_012578.1 346588 346663 D tRNA-Gly 346588..346663 Vibrio cholerae M66-2 7771615 VCM66_tRNAGLY3 tRNA VCM66_tRNAGLY3 NC_012578.1 346698 346773 D tRNA-Gly 346698..346773 Vibrio cholerae M66-2 7774022 VCM66_tRNAGLY4 tRNA VCM66_tRNAGLY4 NC_012578.1 346930 347005 D tRNA-Gly 346930..347005 Vibrio cholerae M66-2 7774023 VCM66_tRNAMET1 tRNA VCM66_tRNAMET1 NC_012578.1 347045 347121 D tRNA-Met 347045..347121 Vibrio cholerae M66-2 7774024 VCM66_tRNAGLY5 tRNA VCM66_tRNAGLY5 NC_012578.1 347156 347231 D tRNA-Gly 347156..347231 Vibrio cholerae M66-2 7774046 VCM66_tRNAMET2 tRNA VCM66_tRNAMET2 NC_012578.1 347418 347494 D tRNA-Met 347418..347494 Vibrio cholerae M66-2 7774025 VCM66_tRNAMET3 tRNA VCM66_tRNAMET3 NC_012578.1 347537 347613 D tRNA-Met 347537..347613 Vibrio cholerae M66-2 7774047 VCM66_tRNAMET4 tRNA VCM66_tRNAMET4 NC_012578.1 347656 347732 D tRNA-Met 347656..347732 Vibrio cholerae M66-2 7774048 VCM66_tRNAILE2 tRNA VCM66_tRNAILE2 NC_012578.1 388076 388152 D tRNA-Ile 388076..388152 Vibrio cholerae M66-2 7773971 VCM66_tRNAALA4 tRNA VCM66_tRNAALA4 NC_012578.1 388161 388236 D tRNA-Ala 388161..388236 Vibrio cholerae M66-2 7774031 VCM66_tRNAASP3 tRNA VCM66_tRNAASP3 NC_012578.1 391682 391758 D tRNA-Asp 391682..391758 Vibrio cholerae M66-2 7773985 VCM66_tRNAASN4 tRNA VCM66_tRNAASN4 NC_012578.1 463157 463232 R tRNA-Asn complement(463157..463232) Vibrio cholerae M66-2 7771720 VCM66_tRNATHR6 tRNA VCM66_tRNATHR6 NC_012578.1 463247 463322 R tRNA-Thr complement(463247..463322) Vibrio cholerae M66-2 7774006 VCM66_tRNAASN3 tRNA VCM66_tRNAASN3 NC_012578.1 463351 463426 R tRNA-Asn complement(463351..463426) Vibrio cholerae M66-2 7774072 VCM66_tRNATHR5 tRNA VCM66_tRNATHR5 NC_012578.1 463442 463517 R tRNA-Thr complement(463442..463517) Vibrio cholerae M66-2 7774005 VCM66_tRNAPHE3 tRNA VCM66_tRNAPHE3 NC_012578.1 463559 463634 R tRNA-Phe complement(463559..463634) Vibrio cholerae M66-2 7774071 VCM66_tRNAASN2 tRNA VCM66_tRNAASN2 NC_012578.1 465930 466005 R tRNA-Asn complement(465930..466005) Vibrio cholerae M66-2 7771721 VCM66_tRNAPHE2 tRNA VCM66_tRNAPHE2 NC_012578.1 466043 466118 R tRNA-Phe complement(466043..466118) Vibrio cholerae M66-2 7774004 VCM66_tRNATHR4 tRNA VCM66_tRNATHR4 NC_012578.1 466129 466204 R tRNA-Thr complement(466129..466204) Vibrio cholerae M66-2 7774056 VCM66_tRNAPHE1 tRNA VCM66_tRNAPHE1 NC_012578.1 466253 466328 R tRNA-Phe complement(466253..466328) Vibrio cholerae M66-2 7774070 VCM66_tRNAMET9 tRNA VCM66_tRNAMET9 NC_012578.1 507632 507707 R tRNA-Met complement(507632..507707) Vibrio cholerae M66-2 7771761 VCM66_tRNASER2 tRNA VCM66_tRNASER2 NC_012578.1 538415 538507 D tRNA-Ser 538415..538507 Vibrio cholerae M66-2 7771793 VCM66_tRNAARG2 tRNA VCM66_tRNAARG2 NC_012578.1 538541 538617 D tRNA-Arg 538541..538617 Vibrio cholerae M66-2 7774063 VCM66_tRNASER3 tRNA VCM66_tRNASER3 NC_012578.1 538640 538732 D tRNA-Ser 538640..538732 Vibrio cholerae M66-2 7773996 VCM66_tRNAARG3 tRNA VCM66_tRNAARG3 NC_012578.1 538799 538875 D tRNA-Arg 538799..538875 Vibrio cholerae M66-2 7774064 VCM66_tRNAARG4 tRNA VCM66_tRNAARG4 NC_012578.1 538931 539007 D tRNA-Arg 538931..539007 Vibrio cholerae M66-2 7773997 VCM66_tRNAARG5 tRNA VCM66_tRNAARG5 NC_012578.1 539080 539156 D tRNA-Arg 539080..539156 Vibrio cholerae M66-2 7773998 VCM66_tRNAARG6 tRNA VCM66_tRNAARG6 NC_012578.1 539213 539289 D tRNA-Arg 539213..539289 Vibrio cholerae M66-2 7773999 VCM66_tRNAARG7 tRNA VCM66_tRNAARG7 NC_012578.1 539361 539437 D tRNA-Arg 539361..539437 Vibrio cholerae M66-2 7774000 VCM66_tRNALEU1 tRNA VCM66_tRNALEU1 NC_012578.1 640376 640459 D tRNA-Leu 640376..640459 Vibrio cholerae M66-2 7771883 VCM66_tRNAMET5 tRNA VCM66_tRNAMET5 NC_012578.1 640513 640589 D tRNA-Met 640513..640589 Vibrio cholerae M66-2 7774033 VCM66_tRNAGLU3 tRNA VCM66_tRNAGLU3 NC_012578.1 721828 721903 D tRNA-Glu 721828..721903 Vibrio cholerae M66-2 7773972 VCM66_tRNAASP4 tRNA VCM66_tRNAASP4 NC_012578.1 725398 725474 D tRNA-Asp 725398..725474 Vibrio cholerae M66-2 7773986 VCM66_tRNATYR5 tRNA VCM66_tRNATYR5 NC_012578.1 930586 930670 R tRNA-Tyr complement(930586..930670) Vibrio cholerae M66-2 7772148 VCM66_tRNATYR4 tRNA VCM66_tRNATYR4 NC_012578.1 930755 930839 R tRNA-Tyr complement(930755..930839) Vibrio cholerae M66-2 7774078 VCM66_tRNATYR3 tRNA VCM66_tRNATYR3 NC_012578.1 930924 931008 R tRNA-Tyr complement(930924..931008) Vibrio cholerae M66-2 7774077 VCM66_tRNATYR2 tRNA VCM66_tRNATYR2 NC_012578.1 931094 931178 R tRNA-Tyr complement(931094..931178) Vibrio cholerae M66-2 7774076 VCM66_tRNAASN1 tRNA VCM66_tRNAASN1 NC_012578.1 1044563 1044638 R tRNA-Asn complement(1044563..1044638) Vibrio cholerae M66-2 7772253 VCM66_tRNACYS1 tRNA VCM66_tRNACYS1 NC_012578.1 1251353 1251426 D tRNA-Cys 1251353..1251426 Vibrio cholerae M66-2 7772449 VCM66_tRNAGLY6 tRNA VCM66_tRNAGLY6 NC_012578.1 1251429 1251504 D tRNA-Gly 1251429..1251504 Vibrio cholerae M66-2 7774012 VCM66_tRNALEU2 tRNA VCM66_tRNALEU2 NC_012578.1 1251569 1251655 D tRNA-Leu 1251569..1251655 Vibrio cholerae M66-2 7774026 VCM66_tRNAGLY7 tRNA VCM66_tRNAGLY7 NC_012578.1 1251666 1251741 D tRNA-Gly 1251666..1251741 Vibrio cholerae M66-2 7774034 VCM66_tRNAVAL4 tRNA VCM66_tRNAVAL4 NC_012578.1 1660113 1660189 R tRNA-Val complement(1660113..1660189) Vibrio cholerae M66-2 7772813 VCM66_tRNAVAL3 tRNA VCM66_tRNAVAL3 NC_012578.1 1660211 1660287 R tRNA-Val complement(1660211..1660287) Vibrio cholerae M66-2 7774082 VCM66_tRNASER4 tRNA VCM66_tRNASER4 NC_012578.1 1842826 1842913 D tRNA-Ser 1842826..1842913 Vibrio cholerae M66-2 7772966 VCM66_tRNAARG8 tRNA VCM66_tRNAARG8 NC_012578.1 2030339 2030415 R tRNA-Arg complement(2030339..2030415) Vibrio cholerae M66-2 7773133 VCM66_tRNAPRO3 tRNA VCM66_tRNAPRO3 NC_012578.1 2136263 2136339 D tRNA-Pro 2136263..2136339 Vibrio cholerae M66-2 7773230 VCM66_tRNASER5 tRNA VCM66_tRNASER5 NC_012578.1 2136504 2136594 D tRNA-Ser 2136504..2136594 Vibrio cholerae M66-2 7774060 VCM66_tRNAMET6 tRNA VCM66_tRNAMET6 NC_012578.1 2267917 2267993 D tRNA-Met 2267917..2267993 Vibrio cholerae M66-2 7773372 VCM66_tRNALEU3 tRNA VCM66_tRNALEU3 NC_012578.1 2268022 2268107 D tRNA-Leu 2268022..2268107 Vibrio cholerae M66-2 7774051 VCM66_tRNALEU4 tRNA VCM66_tRNALEU4 NC_012578.1 2268132 2268216 D tRNA-Leu 2268132..2268216 Vibrio cholerae M66-2 7774035 VCM66_tRNAGLN1 tRNA VCM66_tRNAGLN1 NC_012578.1 2268244 2268318 D tRNA-Gln 2268244..2268318 Vibrio cholerae M66-2 7774036 VCM66_tRNAMET7 tRNA VCM66_tRNAMET7 NC_012578.1 2268396 2268472 D tRNA-Met 2268396..2268472 Vibrio cholerae M66-2 7774013 VCM66_tRNALEU5 tRNA VCM66_tRNALEU5 NC_012578.1 2268496 2268581 D tRNA-Leu 2268496..2268581 Vibrio cholerae M66-2 7774052 VCM66_tRNAGLN2 tRNA VCM66_tRNAGLN2 NC_012578.1 2268599 2268673 D tRNA-Gln 2268599..2268673 Vibrio cholerae M66-2 7774037 VCM66_tRNALEU6 tRNA VCM66_tRNALEU6 NC_012578.1 2268715 2268799 D tRNA-Leu 2268715..2268799 Vibrio cholerae M66-2 7774014 VCM66_tRNAGLN3 tRNA VCM66_tRNAGLN3 NC_012578.1 2268826 2268900 D tRNA-Gln 2268826..2268900 Vibrio cholerae M66-2 7774038 VCM66_tRNALEU7 tRNA VCM66_tRNALEU7 NC_012578.1 2268942 2269026 D tRNA-Leu 2268942..2269026 Vibrio cholerae M66-2 7774015 VCM66_tRNAMET8 tRNA VCM66_tRNAMET8 NC_012578.1 2269052 2269128 D tRNA-Met 2269052..2269128 Vibrio cholerae M66-2 7774039 VCM66_tRNALEU8 tRNA VCM66_tRNALEU8 NC_012578.1 2269151 2269236 D tRNA-Leu 2269151..2269236 Vibrio cholerae M66-2 7774053 VCM66_tRNAGLN4 tRNA VCM66_tRNAGLN4 NC_012578.1 2269254 2269328 D tRNA-Gln 2269254..2269328 Vibrio cholerae M66-2 7774040 VCM66_tRNALEU9 tRNA VCM66_tRNALEU9 NC_012578.1 2269372 2269456 D tRNA-Leu 2269372..2269456 Vibrio cholerae M66-2 7774016 VCM66_tRNAGLN5 tRNA VCM66_tRNAGLN5 NC_012578.1 2269495 2269569 D tRNA-Gln 2269495..2269569 Vibrio cholerae M66-2 7774041 VCM66_tRNALEU10 tRNA VCM66_tRNALEU10 NC_012578.1 2269611 2269695 D tRNA-Leu 2269611..2269695 Vibrio cholerae M66-2 7774017 VCM66_tRNAPRO4 tRNA VCM66_tRNAPRO4 NC_012578.1 2312637 2312713 R tRNA-Pro complement(2312637..2312713) Vibrio cholerae M66-2 7773406 VCM66_tRNATHR3 tRNA VCM66_tRNATHR3 NC_012578.1 2613155 2613230 R tRNA-Thr complement(2613155..2613230) Vibrio cholerae M66-2 7773987 VCM66_tRNAALA5 tRNA VCM66_tRNAALA5 NC_012578.1 2616698 2616773 R tRNA-Ala complement(2616698..2616773) Vibrio cholerae M66-2 7773980 VCM66_tRNAILE3 tRNA VCM66_tRNAILE3 NC_012578.1 2616782 2616858 R tRNA-Ile complement(2616782..2616858) Vibrio cholerae M66-2 7773994 VCM66_tRNALEU11 tRNA VCM66_tRNALEU11 NC_012578.1 2620376 2620460 R tRNA-Leu complement(2620376..2620460) Vibrio cholerae M66-2 7773678 VCM66_tRNAASP5 tRNA VCM66_tRNAASP5 NC_012578.1 2864921 2864997 R tRNA-Asp complement(2864921..2864997) Vibrio cholerae M66-2 7773927 VCM66_tRNAVAL2 tRNA VCM66_tRNAVAL2 NC_012578.1 2868498 2868573 R tRNA-Val complement(2868498..2868573) Vibrio cholerae M66-2 7773981 VCM66_tRNALYS2 tRNA VCM66_tRNALYS2 NC_012578.1 2868604 2868678 R tRNA-Lys complement(2868604..2868678) Vibrio cholerae M66-2 7774080 VCM66_tRNAGLU1 tRNA VCM66_tRNAGLU1 NC_012578.1 2868698 2868773 R tRNA-Glu complement(2868698..2868773) Vibrio cholerae M66-2 7774045 VCM66_AtRNAGLY tRNA VCM66_AtRNAGLY NC_012580.1 468902 468976 D tRNA-Gly 468902..468976 Vibrio cholerae M66-2 7781797 VCM66_AtRNACYS1 tRNA VCM66_AtRNACYS1 NC_012580.1 673565 673638 R tRNA-Cys complement(673565..673638) Vibrio cholerae M66-2 7780938 VCM66_AtRNALEU tRNA VCM66_AtRNALEU NC_012580.1 673662 673748 R tRNA-Leu complement(673662..673748) Vibrio cholerae M66-2 7781296 VCM66_AtRNACYS2 tRNA VCM66_AtRNACYS2 NC_012580.1 678784 678857 R tRNA-Cys complement(678784..678857) Vibrio cholerae M66-2 7780944 VCM66_16S01 rRNA VCM66_16S01 NC_012578.1 53787 55321 D 16S ribosomal RNA 53787..55321 Vibrio cholerae M66-2 7771357 VCM66_23S01 rRNA VCM66_23S01 NC_012578.1 55748 58634 D 23S ribosomal RNA 55748..58634 Vibrio cholerae M66-2 7773990 VCM66_5S01 rRNA VCM66_5S01 NC_012578.1 58763 58880 D 5S ribosomal RNA 58763..58880 Vibrio cholerae M66-2 7773975 VCM66_16S02 rRNA VCM66_16S02 NC_012578.1 151030 152564 D 16S ribosomal RNA 151030..152564 Vibrio cholerae M66-2 7771455 VCM66_23S02 rRNA VCM66_23S02 NC_012578.1 153278 156164 D 23S ribosomal RNA 153278..156164 Vibrio cholerae M66-2 7773991 VCM66_5S02 rRNA VCM66_5S02 NC_012578.1 156293 156410 D 5S ribosomal RNA 156293..156410 Vibrio cholerae M66-2 7773976 VCM66_16S03 rRNA VCM66_16S03 NC_012578.1 308873 310407 D 16S ribosomal RNA 308873..310407 Vibrio cholerae M66-2 7771588 VCM66_23S03 rRNA VCM66_23S03 NC_012578.1 310919 313805 D 23S ribosomal RNA 310919..313805 Vibrio cholerae M66-2 7773992 VCM66_5S03 rRNA VCM66_5S03 NC_012578.1 313933 314050 D 5S ribosomal RNA 313933..314050 Vibrio cholerae M66-2 7773977 VCM66_16S04 rRNA VCM66_16S04 NC_012578.1 386478 388012 D 16S ribosomal RNA 386478..388012 Vibrio cholerae M66-2 7771661 VCM66_23S04 rRNA VCM66_23S04 NC_012578.1 388524 391410 D 23S ribosomal RNA 388524..391410 Vibrio cholerae M66-2 7773993 VCM66_5S04 rRNA VCM66_5S04 NC_012578.1 391539 391656 D 5S ribosomal RNA 391539..391656 Vibrio cholerae M66-2 7773978 VCM66_16S05 rRNA VCM66_16S05 NC_012578.1 720224 721758 D 16S ribosomal RNA 720224..721758 Vibrio cholerae M66-2 7771954 VCM66_23S05 rRNA VCM66_23S05 NC_012578.1 722191 725077 D 23S ribosomal RNA 722191..725077 Vibrio cholerae M66-2 7774020 VCM66_5S05 rRNA VCM66_5S05 NC_012578.1 725205 725322 D 5S ribosomal RNA 725205..725322 Vibrio cholerae M66-2 7773979 VCM66_5S06 rRNA VCM66_5S06 NC_012578.1 2612997 2613112 R 5S ribosomal RNA complement(2612997..2613112) Vibrio cholerae M66-2 7773676 VCM66_5S07 rRNA VCM66_5S07 NC_012578.1 2613279 2613396 R 5S ribosomal RNA complement(2613279..2613396) Vibrio cholerae M66-2 7774069 VCM66_23S06 rRNA VCM66_23S06 NC_012578.1 2613524 2616410 R 23S ribosomal RNA complement(2613524..2616410) Vibrio cholerae M66-2 7773988 VCM66_16S06 rRNA VCM66_16S06 NC_012578.1 2616922 2618456 R 16S ribosomal RNA complement(2616922..2618456) Vibrio cholerae M66-2 7774032 VCM66_5S08 rRNA VCM66_5S08 NC_012578.1 2865023 2865140 R 5S ribosomal RNA complement(2865023..2865140) Vibrio cholerae M66-2 7774011 VCM66_23S07 rRNA VCM66_23S07 NC_012578.1 2865269 2868155 R 23S ribosomal RNA complement(2865269..2868155) Vibrio cholerae M66-2 7773989 VCM66_16S07 rRNA VCM66_16S07 NC_012578.1 2868843 2870377 R 16S ribosomal RNA complement(2868843..2870377) Vibrio cholerae M66-2 7774018