-- dump date 20140620_141036 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_395138.1 16082692 1172646 88..1110 1 NC_003131.1 putative transposase 1110 1172646 YPCD1.01 Yersinia pestis CO92 putative transposase NP_395138.1 88 D 214092 CDS NP_395139.1 16082693 1172647 1110..1889 1 NC_003131.1 transposase/IS protein 1889 1172647 YPCD1.02 Yersinia pestis CO92 transposase/IS protein NP_395139.1 1110 D 214092 CDS NP_395142.1 16082696 1172650 complement(3014..3406) 1 NC_003131.1 chaperone for YopE; secretion chaperone 3406 yerA 1172650 yerA Yersinia pestis CO92 secretion chaperone NP_395142.1 3014 R 214092 CDS NP_395143.1 16082697 1172651 3600..4259 1 NC_003131.1 secreted effector; putative outer membrane virulence protein 4259 yopE 1172651 yopE Yersinia pestis CO92 putative outer membrane virulence protein NP_395143.1 3600 D 214092 CDS NP_395144.1 16082698 1172652 4261..4557 1 NC_003131.1 Orf75 (f98); similar to gi|927749 hypothetical; hypothetical protein 4557 1172652 YPCD1.07 Yersinia pestis CO92 hypothetical protein NP_395144.1 4261 D 214092 CDS NP_395145.1 16082699 1172653 complement(4399..4698) 1 NC_003131.1 Orf74 (o99); similar to gi|1806203; hypothetical protein 4698 1172653 YPCD1.08c Yersinia pestis CO92 hypothetical protein NP_395145.1 4399 R 214092 CDS NP_395146.2 40548796 1172654 complement(4691..4933) 1 NC_003131.1 Orf73 (o91); similar to gi|1806202; hypothetical protein 4933 1172654 YPCD1.09c Yersinia pestis CO92 hypothetical protein NP_395146.2 4691 R 214092 CDS NP_395148.1 16082702 1172657 complement(6195..7157) 1 NC_003131.1 SopB; plasmid-partitioning protein 7157 sopB 1172657 sopB Yersinia pestis CO92 plasmid-partitioning protein NP_395148.1 6195 R 214092 CDS NP_395149.1 16082703 1172658 complement(7157..8323) 1 NC_003131.1 plasmid-partitioning protein SopA 8323 sopA 1172658 sopA Yersinia pestis CO92 plasmid-partitioning protein SopA NP_395149.1 7157 R 214092 CDS NP_954989.1 40548797 2700523 complement(9123..9320) 1 NC_003131.1 o65; similar to gi|790866 hypothetical protein from Neisseria gonorrhoeae; hypothetical protein 9320 2700523 YPCD1.14n Yersinia pestis CO92 hypothetical protein NP_954989.1 9123 R 214092 CDS NP_395151.1 16082705 1172660 complement(9429..9887) 1 NC_003131.1 hypothetical protein 9887 1172660 YPCD1.15c Yersinia pestis CO92 hypothetical protein NP_395151.1 9429 R 214092 CDS NP_395152.1 16082706 1172661 complement(9911..10234) 1 NC_003131.1 hypothetical protein 10234 1172661 YPCD1.16c Yersinia pestis CO92 hypothetical protein NP_395152.1 9911 R 214092 CDS NP_395154.1 16082708 1172664 complement(11562..12110) 1 NC_003131.1 putative virulence determinant protein; Yop targeting protein 12110 yopQ 1172664 yopQ Yersinia pestis CO92 Yop targeting protein NP_395154.1 11562 R 214092 CDS NP_395155.1 16082709 1172665 12610..13578 1 NC_003131.1 putative cytotoxic effector protein; Yop targeted effector 13578 yopT 1172665 yopT Yersinia pestis CO92 Yop targeted effector NP_395155.1 12610 D 214092 CDS NP_395156.1 16082710 1172666 13578..13976 1 NC_003131.1 YopT chaperone 13976 sycT 1172666 sycT Yersinia pestis CO92 YopT chaperone NP_395156.1 13578 D 214092 CDS NP_395157.1 16082711 1172667 complement(14020..14409) 1 NC_003131.1 ORF61 (o129); hypothetical protein 14409 1172667 YPCD1.22c Yersinia pestis CO92 hypothetical protein NP_395157.1 14020 R 214092 CDS NP_395158.1 16082712 1172668 14681..15100 1 NC_003131.1 Orf60 (f139); hypothetical protein 15100 1172668 YPCD1.23 Yersinia pestis CO92 hypothetical protein NP_395158.1 14681 D 214092 CDS NP_395161.1 16082715 1172671 complement(16336..17565) 1 NC_003131.1 secreted effector protein 17565 yopM 1172671 yopM Yersinia pestis CO92 secreted effector protein NP_395161.1 16336 R 214092 CDS NP_395162.1 16082716 1172673 complement(19294..20214) 1 NC_003131.1 Yop targeting negative regulator; translocon component; important for translocation pore formation; secreted effector protein 20214 yopD 1172673 yopD Yersinia pestis CO92 secreted effector protein NP_395162.1 19294 R 214092 CDS NP_395163.1 16082717 1172674 complement(20233..21438) 1 NC_003131.1 Yop targeting protein; translocon component; important for translocation pore formation; secreted effector protein 21438 yopB 1172674 yopB Yersinia pestis CO92 secreted effector protein NP_395163.1 20233 R 214092 CDS NP_395164.1 16082718 1172675 complement(21416..21922) 1 NC_003131.1 chaperone for YopBD; secretion chaperone 21922 sycD 1172675 sycD Yersinia pestis CO92 secretion chaperone NP_395164.1 21416 R 214092 CDS NP_395165.1 16082719 1172676 complement(21935..22915) 1 NC_003131.1 V antigen; low calcium response protein V; functions in needle complex protein export; Yop secretion and targeting control protein; important for translocation pore formation; induces IL-10 production by macrophages; interacts with Toll-like receptor 2; secreted effector protein 22915 lcrV 1172676 lcrV Yersinia pestis CO92 secreted effector protein NP_395165.1 21935 R 214092 CDS NP_395166.1 16082720 1172677 complement(22917..23204) 1 NC_003131.1 V-antigen; Yop secretion and targeting control protein; low calcium response protein G 23204 lcrG 1172677 lcrG Yersinia pestis CO92 low calcium response protein G NP_395166.1 22917 R 214092 CDS NP_395167.1 16082721 1172678 complement(23246..23686) 1 NC_003131.1 low calcium response protein R 23686 lcrR 1172678 lcrR Yersinia pestis CO92 low calcium response protein R NP_395167.1 23246 R 214092 CDS NP_395168.1 16082722 1172679 complement(23683..25797) 1 NC_003131.1 secretion protein; invasion protein; low calcium response protein D 25797 yscV 1172679 yscV Yersinia pestis CO92 low calcium response protein D NP_395168.1 23683 R 214092 CDS NP_395169.1 16082723 1172680 complement(25784..26128) 1 NC_003131.1 Orf44 (o114); similar to gi|1197038; putative type III secretion protein; hypothetical protein 26128 yscY 1172680 yscY Yersinia pestis CO92 hypothetical protein NP_395169.1 25784 R 214092 CDS NP_395170.1 16082724 1172681 complement(26125..26493) 1 NC_003131.1 Orf43 (o122); similar to gi|2459976; putative type III secretion protein; hypothetical protein 26493 yscX 1172681 yscX Yersinia pestis CO92 hypothetical protein NP_395170.1 26125 R 214092 CDS NP_395171.1 16082725 1172682 complement(26490..26861) 1 NC_003131.1 Orf42 similar to gi|581840; putative type III secretion protein; hypothetical protein 26861 sycN 1172682 sycN Yersinia pestis CO92 hypothetical protein NP_395171.1 26490 R 214092 CDS NP_395172.1 16082726 1172683 complement(26848..27126) 1 NC_003131.1 Yop secretion and targeting control protein 27126 tyeA 1172683 tyeA Yersinia pestis CO92 Yop secretion and targeting control protein NP_395172.1 26848 R 214092 CDS NP_395173.1 16082727 1172684 complement(27107..27988) 1 NC_003131.1 secretion control protein 27988 lcrE 1172684 lcrE Yersinia pestis CO92 secretion control protein NP_395173.1 27107 R 214092 CDS NP_395174.1 16082728 1172685 28186..29505 1 NC_003131.1 Yops secretion protein; type III secretion system ATPase 29505 yscN 1172685 yscN Yersinia pestis CO92 type III secretion system ATPase NP_395174.1 28186 D 214092 CDS NP_395175.1 16082729 1172686 29502..29966 1 NC_003131.1 type III secretion apparatus component 29966 yscO 1172686 yscO Yersinia pestis CO92 type III secretion apparatus component NP_395175.1 29502 D 214092 CDS NP_395176.1 16082730 1172687 29966..31333 1 NC_003131.1 type III secretion apparatus component 31333 yscP 1172687 yscP Yersinia pestis CO92 type III secretion apparatus component NP_395176.1 29966 D 214092 CDS NP_395177.1 16082731 1172688 31330..32253 1 NC_003131.1 type III secretion apparatus component; type III secretion system protein 32253 yscQ 1172688 yscQ Yersinia pestis CO92 type III secretion system protein NP_395177.1 31330 D 214092 CDS NP_395178.1 16082732 1172689 32250..32903 1 NC_003131.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response; type III secretion system protein 32903 yscR 1172689 yscR Yersinia pestis CO92 type III secretion system protein NP_395178.1 32250 D 214092 CDS NP_395179.1 16082733 1172690 32905..33171 1 NC_003131.1 type III secretion apparatus component; needle complex export protein 33171 yscS 1172690 yscS Yersinia pestis CO92 needle complex export protein NP_395179.1 32905 D 214092 CDS NP_395180.1 16082734 1172691 33168..33953 1 NC_003131.1 type III secretion apparatus component; needle complex export protein 33953 yscT 1172691 yscT Yersinia pestis CO92 needle complex export protein NP_395180.1 33168 D 214092 CDS NP_395181.1 16082735 1172692 33953..35017 1 NC_003131.1 type III secretion apparatus component; needle complex export protein 35017 yscU 1172692 yscU Yersinia pestis CO92 needle complex export protein NP_395181.1 33953 D 214092 CDS NP_395182.1 16082736 1172693 35593..35988 1 NC_003131.1 YscC lipoprotein chaperone; stabilizes outer membrane secretin; needle complex outer membrane lipoprotein precursor 35988 virG 1172693 virG Yersinia pestis CO92 needle complex outer membrane lipoprotein precursor NP_395182.1 35593 D 214092 CDS NP_395183.1 16082737 1172694 36112..36927 1 NC_003131.1 LCR activator; putative thermoregulatory protein; transcriptional regulator 36927 virF 1172694 virF Yersinia pestis CO92 transcriptional regulator NP_395183.1 36112 D 214092 CDS NP_395184.1 16082738 1172695 37006..37104 1 NC_003131.1 hypothetical protein 37104 yscA 1172695 yscA Yersinia pestis CO92 hypothetical protein NP_395184.1 37006 D 214092 CDS NP_395185.1 16082739 1172696 37330..37743 1 NC_003131.1 type III secretion apparatus component 37743 yscB 1172696 yscB Yersinia pestis CO92 type III secretion apparatus component NP_395185.1 37330 D 214092 CDS NP_395186.1 16082740 1172697 37749..39572 1 NC_003131.1 forms ring-shaped structure in outer membrane; outer membrane secretin precursor 39572 yscC 1172697 yscC Yersinia pestis CO92 outer membrane secretin precursor NP_395186.1 37749 D 214092 CDS NP_395187.1 16082741 1172698 39569..40828 1 NC_003131.1 type III secretion apparatus component; virulence protein 40828 yscD 1172698 yscD Yersinia pestis CO92 virulence protein NP_395187.1 39569 D 214092 CDS NP_395188.1 16082742 1172699 40825..41025 1 NC_003131.1 type III secretion apparatus component 41025 yscE 1172699 yscE Yersinia pestis CO92 type III secretion apparatus component NP_395188.1 40825 D 214092 CDS NP_395189.1 16082743 1172700 41026..41289 1 NC_003131.1 type III secretion apparatus component; needle complex major subunit 41289 yscF 1172700 yscF Yersinia pestis CO92 needle complex major subunit NP_395189.1 41026 D 214092 CDS NP_395190.1 16082744 1172701 41291..41638 1 NC_003131.1 type III secretion apparatus component 41638 yscG 1172701 yscG Yersinia pestis CO92 type III secretion apparatus component NP_395190.1 41291 D 214092 CDS NP_395191.1 16082745 1172702 41635..42132 1 NC_003131.1 secreted protein 42132 yopR 1172702 yopR Yersinia pestis CO92 secreted protein NP_395191.1 41635 D 214092 CDS NP_395192.1 16082746 1172703 42133..42480 1 NC_003131.1 type III secretion apparatus component 42480 lcrO 1172703 lcrO Yersinia pestis CO92 type III secretion apparatus component NP_395192.1 42133 D 214092 CDS NP_395193.1 16082747 1172704 42487..43221 1 NC_003131.1 needle complex inner membrane lipoprotein 43221 ylpB 1172704 ylpB Yersinia pestis CO92 needle complex inner membrane lipoprotein NP_395193.1 42487 D 214092 CDS NP_395194.1 16082748 1172705 43221..43850 1 NC_003131.1 type III secretion apparatus component 43850 yscK 1172705 yscK Yersinia pestis CO92 type III secretion apparatus component NP_395194.1 43221 D 214092 CDS NP_395195.1 16082749 1172706 43796..44461 1 NC_003131.1 type III secretion apparatus component; type III secretion system protein 44461 yscL 1172706 yscL Yersinia pestis CO92 type III secretion system protein NP_395195.1 43796 D 214092 CDS NP_395196.1 16082750 1172707 44686..45033 1 NC_003131.1 LCR negative regulator 45033 lcrQ 1172707 lcrQ Yersinia pestis CO92 LCR negative regulator NP_395196.1 44686 D 214092 CDS NP_395197.1 16082751 1172708 45581..45847 1 NC_003131.1 putative transposase 45847 lcrS 1172708 lcrS Yersinia pestis CO92 putative transposase NP_395197.1 45581 D 214092 CDS NP_395199.1 16082753 1172710 46302..46610 1 NC_003131.1 putative transposase 46610 ORFC 1172710 ORFC Yersinia pestis CO92 putative transposase NP_395199.1 46302 D 214092 CDS NP_395201.1 16082755 1172712 complement(47122..48528) 1 NC_003131.1 putative secreted protein-tyrosine phosphatase 48528 yopH 1172712 yopH Yersinia pestis CO92 putative secreted protein-tyrosine phosphatase NP_395201.1 47122 R 214092 CDS NP_395205.1 16082759 1172716 complement(50211..51077) 1 NC_003131.1 targeted effector protein 51077 yopJ 1172716 yopJ Yersinia pestis CO92 targeted effector protein NP_395205.1 50211 R 214092 CDS NP_395206.1 16082760 1172717 complement(51473..53671) 1 NC_003131.1 secreted protein kinase 53671 ypkA 1172717 ypkA Yersinia pestis CO92 secreted protein kinase NP_395206.1 51473 R 214092 CDS NP_395207.1 16082761 1172718 complement(53679..54128) 1 NC_003131.1 Orf7 (o142); similar to gi|2149940 orf1 from Pseudomonas syringae; hypothetical protein 54128 1172718 YPCD1.73c Yersinia pestis CO92 hypothetical protein NP_395207.1 53679 R 214092 CDS NP_395210.1 16082764 1172722 complement(56291..57157) 1 NC_003131.1 replication protein 57157 repA1 1172722 repA1 Yersinia pestis CO92 replication protein NP_395210.1 56291 R 214092 CDS NP_395211.1 16082765 1172723 complement(57150..57224) 1 NC_003131.1 acts to regulate the expression of the plasmid replication protein RepA in the IncFII plasmid group; RepA leader peptide Tap 57224 tap 1172723 tap Yersinia pestis CO92 RepA leader peptide Tap NP_395211.1 57150 R 214092 CDS NP_395212.1 16082766 1172724 complement(57466..57720) 1 NC_003131.1 replication protein 57720 copB 1172724 copB Yersinia pestis CO92 replication protein NP_395212.1 57466 R 214092 CDS NP_395219.1 16082773 1172735 complement(62851..65166) 1 NC_003131.1 putative transposase 65166 tnpA 1172735 tnpA Yersinia pestis CO92 putative transposase NP_395219.1 62851 R 214092 CDS NP_395220.1 16082774 1172736 65330..65881 1 NC_003131.1 putative resolvase 65881 tnpR 1172736 tnpR Yersinia pestis CO92 putative resolvase NP_395220.1 65330 D 214092 CDS NP_954990.1 40548798 2700521 65900..66364 1 NC_003131.1 Orf85 (f154); similar to gi|1360613; hypothetical protein 66364 2700521 YPCD1.91n Yersinia pestis CO92 hypothetical protein NP_954990.1 65900 D 214092 CDS NP_395221.1 16082775 1172737 66503..66832 1 NC_003131.1 Orf84 (f109); similar to gi|2826244 type I restriction-modification enzyme; hypothetical protein 66832 1172737 YPCD1.92 Yersinia pestis CO92 hypothetical protein NP_395221.1 66503 D 214092 CDS NP_395222.1 16082776 1172738 66932..67198 1 NC_003131.1 putative transposase 67198 1172738 YPCD1.93 Yersinia pestis CO92 putative transposase NP_395222.1 66932 D 214092 CDS NP_395223.1 16082777 1172739 67222..68031 1 NC_003131.1 putative transposase 68031 1172739 YPCD1.94 Yersinia pestis CO92 putative transposase NP_395223.1 67222 D 214092 CDS NP_395224.1 16082778 1172740 complement(68179..68604) 1 NC_003131.1 chaperone for YopH; secretion chaperone 68604 sycH 1172740 sycH Yersinia pestis CO92 secretion chaperone NP_395224.1 68179 R 214092 CDS NP_395225.1 16082779 1172741 complement(68947..69378) 1 NC_003131.1 putative transposase 69378 1172741 YPCD1.96c Yersinia pestis CO92 putative transposase NP_395225.1 68947 R 214092 CDS NP_395226.1 16082780 1172742 complement(69378..70304) 1 NC_003131.1 putative transposase 70304 1172742 YPCD1.97c Yersinia pestis CO92 putative transposase NP_395226.1 69378 R 214092 CDS NP_395227.1 16082680 1172637 87..1109 1 NC_003132.1 probable IS100 transposase; similar to TR:P74993; similar to TRA6_BACST putative transposase for insertion sequence element IS5376; contains helix-turn-helix motif from aa 19-40; putative transposase 1109 1172637 YPPCP1.01 Yersinia pestis CO92 putative transposase NP_395227.1 87 D 214092 CDS NP_395228.1 16082681 1172638 1106..1888 1 NC_003132.1 IS100 ATP-binding protein; similar to TR:P74994; similar to ISTB_ECOLI insertion sequence IS21 putative ATP-binding protein; contains PS00017 ATP/GTP-binding site motif A; P-loop; transposase/IS protein 1888 1172638 YPPCP1.02 Yersinia pestis CO92 transposase/IS protein NP_395228.1 1106 D 214092 CDS NP_395229.1 16082682 1172639 2925..3119 1 NC_003132.1 plasmid replication regulatory protein; similar to ROP_ECOLI regulatory protein ROP from ColE1; RNA one modulator; putative replication regulatory protein 3119 rop 1172639 rop Yersinia pestis CO92 putative replication regulatory protein NP_395229.1 2925 D 214092 CDS NP_395230.1 16082683 1172640 4355..4780 1 NC_003132.1 pesticin immunity protein; similar to TR:Q57285 (EMBL:Z54145; X92856); pesticin immunity protein 4780 pim 1172640 pim Yersinia pestis CO92 pesticin immunity protein NP_395230.1 4355 D 214092 CDS NP_395231.1 16082684 1172641 complement(4815..5888) 1 NC_003132.1 similar to TR:Q57159 (EMBL:X92856); pesticin 5888 pst 1172641 pst Yersinia pestis CO92 pesticin NP_395231.1 4815 R 214092 CDS NP_395232.1 16082685 1172642 6006..6422 1 NC_003132.1 hypothetical protein 6422 1172642 YPPCP1.06 Yersinia pestis CO92 hypothetical protein NP_395232.1 6006 D 214092 CDS NP_395233.1 16082686 1172643 6665..7603 1 NC_003132.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 7603 pla 1172643 pla Yersinia pestis CO92 outer membrane protease NP_395233.1 6665 D 214092 CDS NP_395234.1 16082687 1172644 complement(7790..8089) 1 NC_003132.1 similar to predicted transcriptional regulator TR:P95258 (EMBL:Z84498) Mycobacterium tuberculosis MTCY09F9.0 8C (Rv1956); contains helix-turn-helix motif from aa 42-63; putative transcriptional regulator 8089 1172644 YPPCP1.08c Yersinia pestis CO92 putative transcriptional regulator NP_395234.1 7790 R 214092 CDS NP_395235.1 16082688 1172645 complement(8089..8436) 1 NC_003132.1 similar to two hypothetical proteins from Mycobacterium tuberculosis TR:O53468 (EMBL:O53468) MTV018.09C (Rv2022c); similar to TR:O53332 (EMBL:AL021646) MTV014.26 (Rv3182); label: YPPCP1.09c; hypothetical protein 8436 1172645 YPPCP1.09c Yersinia pestis CO92 hypothetical protein NP_395235.1 8089 R 214092 CDS NP_395336.1 16082782 1172744 87..1109 1 NC_003134.1 putative transposase 1109 1172744 YPMT1.01 Yersinia pestis CO92 putative transposase NP_395336.1 87 D 214092 CDS NP_395337.2 40787861 1172745 1109..1888 1 NC_003134.1 transposase/IS protein 1888 1172745 YPMT1.02 Yersinia pestis CO92 transposase/IS protein NP_395337.2 1109 D 214092 CDS NP_395338.1 16082784 1172746 complement(2022..2630) 1 NC_003134.1 tail fiber assembly protein G 2630 1172746 YPMT1.03c Yersinia pestis CO92 tail fiber assembly protein G NP_395338.1 2022 R 214092 CDS NP_395340.2 40787862 1172747 complement(2932..5868) 1 NC_003134.1 putative phage tail protein 5868 1172747 YPMT1.04c Yersinia pestis CO92 putative phage tail protein NP_395340.2 2932 R 214092 CDS NP_395341.1 16082787 1172748 complement(5901..6518) 1 NC_003134.1 hypothetical protein 6518 1172748 YPMT1.05c Yersinia pestis CO92 hypothetical protein NP_395341.1 5901 R 214092 CDS NP_395342.1 16082788 1172749 complement(6536..11173) 1 NC_003134.1 host specificity protein J 11173 1172749 YPMT1.06c Yersinia pestis CO92 host specificity protein J NP_395342.1 6536 R 214092 CDS NP_395343.1 16082789 1172750 complement(11189..11776) 1 NC_003134.1 putative phage tail protein 11776 1172750 YPMT1.07c Yersinia pestis CO92 putative phage tail protein NP_395343.1 11189 R 214092 CDS NP_395344.1 16082790 1172751 complement(11764..12561) 1 NC_003134.1 putative phage tail protein 12561 1172751 YPMT1.08c Yersinia pestis CO92 putative phage tail protein NP_395344.1 11764 R 214092 CDS NP_395345.1 16082791 1172752 complement(12554..13285) 1 NC_003134.1 minor tail fiber protein L 13285 1172752 YPMT1.09c Yersinia pestis CO92 minor tail fiber protein L NP_395345.1 12554 R 214092 CDS NP_395346.1 16082792 1172753 complement(13342..13677) 1 NC_003134.1 minor tail fiber protein M 13677 1172753 YPMT1.10c Yersinia pestis CO92 minor tail fiber protein M NP_395346.1 13342 R 214092 CDS NP_395347.1 16082793 1172754 complement(13719..18296) 1 NC_003134.1 hypothetical protein 18296 1172754 YPMT1.11c Yersinia pestis CO92 hypothetical protein NP_395347.1 13719 R 214092 CDS NP_395348.1 16082794 1172755 complement(18304..18573) 1 NC_003134.1 hypothetical protein 18573 1172755 YPMT1.12c Yersinia pestis CO92 hypothetical protein NP_395348.1 18304 R 214092 CDS NP_395349.1 16082795 1172756 complement(18654..18971) 1 NC_003134.1 hypothetical protein 18971 1172756 YPMT1.13c Yersinia pestis CO92 hypothetical protein NP_395349.1 18654 R 214092 CDS NP_395350.1 16082796 1172757 complement(19031..19777) 1 NC_003134.1 hypothetical protein 19777 1172757 YPMT1.14c Yersinia pestis CO92 hypothetical protein NP_395350.1 19031 R 214092 CDS NP_395351.1 16082797 1172758 complement(19852..20235) 1 NC_003134.1 hypothetical protein 20235 1172758 YPMT1.15c Yersinia pestis CO92 hypothetical protein NP_395351.1 19852 R 214092 CDS NP_395352.1 16082798 1172759 complement(20237..20710) 1 NC_003134.1 hypothetical protein 20710 1172759 YPMT1.16c Yersinia pestis CO92 hypothetical protein NP_395352.1 20237 R 214092 CDS NP_395353.1 16082799 1172760 complement(20701..21159) 1 NC_003134.1 hypothetical protein 21159 1172760 YPMT1.17c Yersinia pestis CO92 hypothetical protein NP_395353.1 20701 R 214092 CDS NP_395354.1 16082800 1172761 complement(21143..21976) 1 NC_003134.1 hypothetical protein 21976 1172761 YPMT1.18c Yersinia pestis CO92 hypothetical protein NP_395354.1 21143 R 214092 CDS NP_395355.1 16082801 1172762 complement(21976..22410) 1 NC_003134.1 hypothetical protein 22410 1172762 YPMT1.19c Yersinia pestis CO92 hypothetical protein NP_395355.1 21976 R 214092 CDS NP_395356.1 16082802 1172763 complement(22454..23116) 1 NC_003134.1 hypothetical protein 23116 1172763 YPMT1.20c Yersinia pestis CO92 hypothetical protein NP_395356.1 22454 R 214092 CDS NP_395357.1 16082803 1172764 complement(23191..24066) 1 NC_003134.1 hypothetical protein 24066 1172764 YPMT1.21c Yersinia pestis CO92 hypothetical protein NP_395357.1 23191 R 214092 CDS NP_395358.1 16082804 1172765 complement(24093..24926) 1 NC_003134.1 hypothetical protein 24926 1172765 YPMT1.22c Yersinia pestis CO92 hypothetical protein NP_395358.1 24093 R 214092 CDS NP_395359.1 16082805 1172766 complement(24949..26538) 1 NC_003134.1 hypothetical protein 26538 1172766 YPMT1.23c Yersinia pestis CO92 hypothetical protein NP_395359.1 24949 R 214092 CDS NP_395360.1 16082806 1172767 complement(26557..27813) 1 NC_003134.1 hypothetical protein 27813 1172767 YPMT1.24c Yersinia pestis CO92 hypothetical protein NP_395360.1 26557 R 214092 CDS NP_395361.1 16082807 1172769 complement(27816..28457) 1 NC_003134.1 hypothetical protein 28457 1172769 YPMT1.25c Yersinia pestis CO92 hypothetical protein NP_395361.1 27816 R 214092 CDS NP_395362.1 16082808 1172768 complement(28653..28919) 1 NC_003134.1 hypothetical protein 28919 1172768 YPMT1.25Ac Yersinia pestis CO92 hypothetical protein NP_395362.1 28653 R 214092 CDS NP_395363.1 16082809 1172771 complement(28929..29828) 1 NC_003134.1 hypothetical protein 29828 1172771 YPMT1.26c Yersinia pestis CO92 hypothetical protein NP_395363.1 28929 R 214092 CDS NP_395364.1 16082810 1172770 complement(29825..30079) 1 NC_003134.1 hypothetical protein 30079 1172770 YPMT1.26Ac Yersinia pestis CO92 hypothetical protein NP_395364.1 29825 R 214092 CDS NP_395365.2 40787863 1172772 complement(30072..30710) 1 NC_003134.1 putative ABC transporter ATP-binding protein 30710 1172772 YPMT1.27c Yersinia pestis CO92 putative ABC transporter ATP-binding protein NP_395365.2 30072 R 214092 CDS NP_395366.1 16082812 1172773 complement(30707..31375) 1 NC_003134.1 hypothetical protein 31375 1172773 YPMT1.28c Yersinia pestis CO92 hypothetical protein NP_395366.1 30707 R 214092 CDS NP_395367.1 16082813 1172774 complement(31375..32073) 1 NC_003134.1 hypothetical protein 32073 1172774 YPMT1.29c Yersinia pestis CO92 hypothetical protein NP_395367.1 31375 R 214092 CDS NP_395368.1 16082814 1172775 32138..33697 1 NC_003134.1 hypothetical protein 33697 1172775 YPMT1.30 Yersinia pestis CO92 hypothetical protein NP_395368.1 32138 D 214092 CDS NP_395369.1 16082815 1172776 33700..33978 1 NC_003134.1 hypothetical protein 33978 1172776 YPMT1.31 Yersinia pestis CO92 hypothetical protein NP_395369.1 33700 D 214092 CDS NP_395370.1 16082816 1172777 34038..34460 1 NC_003134.1 putative lipoprotein 34460 1172777 YPMT1.32 Yersinia pestis CO92 putative lipoprotein NP_395370.1 34038 D 214092 CDS NP_395371.1 16082817 1172778 34465..34992 1 NC_003134.1 putative transcriptional regulator 34992 1172778 YPMT1.33 Yersinia pestis CO92 putative transcriptional regulator NP_395371.1 34465 D 214092 CDS NP_395372.1 16082818 1172779 35314..35964 1 NC_003134.1 hypothetical protein 35964 1172779 YPMT1.34 Yersinia pestis CO92 hypothetical protein NP_395372.1 35314 D 214092 CDS NP_395373.1 16082819 1172780 36049..36276 1 NC_003134.1 hypothetical protein 36276 1172780 YPMT1.34A Yersinia pestis CO92 hypothetical protein NP_395373.1 36049 D 214092 CDS NP_955485.1 40787864 2700863 36577..36936 1 NC_003134.1 hypothetical protein 36936 2700863 YPMT1.34N Yersinia pestis CO92 hypothetical protein NP_955485.1 36577 D 214092 CDS NP_395374.1 16082820 1172781 complement(36915..37397) 1 NC_003134.1 hypothetical protein 37397 1172781 YPMT1.35c Yersinia pestis CO92 hypothetical protein NP_395374.1 36915 R 214092 CDS NP_955486.1 40787865 2700862 complement(37410..37643) 1 NC_003134.1 hypothetical protein 37643 2700862 YPMT1.35N Yersinia pestis CO92 hypothetical protein NP_955486.1 37410 R 214092 CDS NP_395375.1 16082821 1172782 complement(37603..37890) 1 NC_003134.1 hypothetical protein 37890 1172782 YPMT1.36c Yersinia pestis CO92 hypothetical protein NP_395375.1 37603 R 214092 CDS NP_395376.2 40787866 1172783 complement(38084..38593) 1 NC_003134.1 putative transposase 38593 1172783 YPMT1.37c Yersinia pestis CO92 putative transposase NP_395376.2 38084 R 214092 CDS NP_395377.1 16082823 1172784 complement(38751..39320) 1 NC_003134.1 hypothetical protein 39320 1172784 YPMT1.38c Yersinia pestis CO92 hypothetical protein NP_395377.1 38751 R 214092 CDS NP_395378.1 16082824 1172785 complement(39333..40079) 1 NC_003134.1 hypothetical protein 40079 1172785 YPMT1.39c Yersinia pestis CO92 hypothetical protein NP_395378.1 39333 R 214092 CDS NP_395379.1 16082825 1172788 complement(40069..41985) 1 NC_003134.1 putative exonuclease subunit 2 41985 1172788 YPMT1.40c Yersinia pestis CO92 putative exonuclease subunit 2 NP_395379.1 40069 R 214092 CDS NP_395380.1 16082826 1172787 complement(41994..42218) 1 NC_003134.1 hypothetical protein 42218 1172787 YPMT1.40Ac Yersinia pestis CO92 hypothetical protein NP_395380.1 41994 R 214092 CDS NP_395381.1 16082827 1172789 complement(42215..43300) 1 NC_003134.1 putative exonuclease subunit 1 43300 1172789 YPMT1.41c Yersinia pestis CO92 putative exonuclease subunit 1 NP_395381.1 42215 R 214092 CDS NP_395382.1 16082828 1172790 43716..44738 1 NC_003134.1 putative periplasmic protein 44738 1172790 YPMT1.42 Yersinia pestis CO92 putative periplasmic protein NP_395382.1 43716 D 214092 CDS NP_395383.1 16082829 1172743 complement(44876..45022) 1 NC_003134.1 hypothetical protein 45022 1172743 YPMT1.42Ac Yersinia pestis CO92 hypothetical protein NP_395383.1 44876 R 214092 CDS NP_395384.1 16082830 1172791 complement(45098..45742) 1 NC_003134.1 hypothetical protein 45742 1172791 YPMT1.43c Yersinia pestis CO92 hypothetical protein NP_395384.1 45098 R 214092 CDS NP_395385.1 16082831 1172792 46487..47551 1 NC_003134.1 putative replication protein A 47551 1172792 YPMT1.44 Yersinia pestis CO92 putative replication protein A NP_395385.1 46487 D 214092 CDS NP_395386.1 16082832 1172793 complement(48120..48335) 1 NC_003134.1 hypothetical protein 48335 1172793 YPMT1.45c Yersinia pestis CO92 hypothetical protein NP_395386.1 48120 R 214092 CDS NP_395387.1 16082833 1172796 complement(48332..48667) 1 NC_003134.1 hypothetical protein 48667 1172796 YPMT1.46c Yersinia pestis CO92 hypothetical protein NP_395387.1 48332 R 214092 CDS NP_395388.1 16082834 1172794 complement(48664..48843) 1 NC_003134.1 hypothetical protein 48843 1172794 YPMT1.46Ac Yersinia pestis CO92 hypothetical protein NP_395388.1 48664 R 214092 CDS NP_395389.1 16082835 1172795 complement(48884..49159) 1 NC_003134.1 hypothetical protein 49159 1172795 YPMT1.46Bc Yersinia pestis CO92 hypothetical protein NP_395389.1 48884 R 214092 CDS NP_395390.1 16082836 1172797 complement(49227..49637) 1 NC_003134.1 hypothetical protein 49637 1172797 YPMT1.47c Yersinia pestis CO92 hypothetical protein NP_395390.1 49227 R 214092 CDS NP_395391.1 16082837 1172798 complement(49621..49992) 1 NC_003134.1 hypothetical protein 49992 1172798 YPMT1.48c Yersinia pestis CO92 hypothetical protein NP_395391.1 49621 R 214092 CDS NP_395392.1 16082838 1172800 complement(50146..50976) 1 NC_003134.1 putative lipoprotein 50976 1172800 YPMT1.49c Yersinia pestis CO92 putative lipoprotein NP_395392.1 50146 R 214092 CDS NP_395393.1 16082839 1172799 complement(50980..51180) 1 NC_003134.1 hypothetical protein 51180 1172799 YPMT1.49Ac Yersinia pestis CO92 hypothetical protein NP_395393.1 50980 R 214092 CDS NP_395394.1 16082840 1172802 complement(51271..52347) 1 NC_003134.1 putative recombinase 52347 1172802 YPMT1.50c Yersinia pestis CO92 putative recombinase NP_395394.1 51271 R 214092 CDS NP_395395.1 16082841 1172801 complement(52350..52616) 1 NC_003134.1 hypothetical protein 52616 1172801 YPMT1.50Ac Yersinia pestis CO92 hypothetical protein NP_395395.1 52350 R 214092 CDS NP_395396.1 16082842 1172803 complement(52616..53560) 1 NC_003134.1 putative exonuclease 53560 1172803 YPMT1.51c Yersinia pestis CO92 putative exonuclease NP_395396.1 52616 R 214092 CDS NP_395397.1 16082843 1172804 complement(53621..54649) 1 NC_003134.1 hypothetical protein 54649 1172804 YPMT1.52c Yersinia pestis CO92 hypothetical protein NP_395397.1 53621 R 214092 CDS NP_395398.1 16082844 1172805 complement(54769..55242) 1 NC_003134.1 hypothetical protein 55242 1172805 YPMT1.53c Yersinia pestis CO92 hypothetical protein NP_395398.1 54769 R 214092 CDS NP_395399.1 16082845 1172806 55745..56308 1 NC_003134.1 hypothetical protein 56308 1172806 YPMT1.54 Yersinia pestis CO92 hypothetical protein NP_395399.1 55745 D 214092 CDS NP_395400.1 16082846 1172807 complement(56338..56781) 1 NC_003134.1 hypothetical protein 56781 1172807 YPMT1.55c Yersinia pestis CO92 hypothetical protein NP_395400.1 56338 R 214092 CDS NP_395401.1 16082847 1172809 complement(57333..58115) 1 NC_003134.1 transposase/IS protein 58115 1172809 YPMT1.57c Yersinia pestis CO92 transposase/IS protein NP_395401.1 57333 R 214092 CDS NP_395402.1 16082848 1172810 complement(58112..59134) 1 NC_003134.1 transposase 59134 1172810 YPMT1.58c Yersinia pestis CO92 transposase NP_395402.1 58112 R 214092 CDS NP_395403.1 16082849 1172811 complement(59258..61267) 1 NC_003134.1 putative DNA-binding protein 61267 1172811 YPMT1.59c Yersinia pestis CO92 putative DNA-binding protein NP_395403.1 59258 R 214092 CDS NP_395404.1 16082850 1172812 complement(61340..61570) 1 NC_003134.1 hypothetical protein 61570 1172812 YPMT1.60c Yersinia pestis CO92 hypothetical protein NP_395404.1 61340 R 214092 CDS NP_395405.1 16082851 1172813 complement(62283..62789) 1 NC_003134.1 antirestriction protein 62789 1172813 YPMT1.61c Yersinia pestis CO92 antirestriction protein NP_395405.1 62283 R 214092 CDS NP_955487.1 40787867 2700864 62997..63347 1 NC_003134.1 hypothetical protein 63347 2700864 YPMT1.61N Yersinia pestis CO92 hypothetical protein NP_955487.1 62997 D 214092 CDS NP_395406.1 16082852 1172814 complement(63188..63967) 1 NC_003134.1 hypothetical protein 63967 1172814 YPMT1.62c Yersinia pestis CO92 hypothetical protein NP_395406.1 63188 R 214092 CDS NP_395407.2 40787868 1172816 complement(64021..64440) 1 NC_003134.1 hypothetical protein 64440 1172816 YPMT1.63c Yersinia pestis CO92 hypothetical protein NP_395407.2 64021 R 214092 CDS NP_395408.1 16082854 1172815 complement(64451..64672) 1 NC_003134.1 hypothetical protein 64672 1172815 YPMT1.63Ac Yersinia pestis CO92 hypothetical protein NP_395408.1 64451 R 214092 CDS NP_395409.1 16082855 1172817 complement(64672..65349) 1 NC_003134.1 putative methylase 65349 1172817 YPMT1.64c Yersinia pestis CO92 putative methylase NP_395409.1 64672 R 214092 CDS NP_955488.1 40787869 2700865 64969..65496 1 NC_003134.1 hypothetical protein 65496 2700865 YPMT1.64N Yersinia pestis CO92 hypothetical protein NP_955488.1 64969 D 214092 CDS NP_395410.1 16082856 1172818 65742..66050 1 NC_003134.1 hypothetical protein 66050 1172818 YPMT1.65 Yersinia pestis CO92 hypothetical protein NP_395410.1 65742 D 214092 CDS NP_395411.1 16082857 1172819 complement(66212..67609) 1 NC_003134.1 putative DNA-binding protein 67609 1172819 YPMT1.66c Yersinia pestis CO92 putative DNA-binding protein NP_395411.1 66212 R 214092 CDS NP_395412.1 16082858 1172820 complement(67988..68959) 1 NC_003134.1 partitioning protein B 68959 parB 1172820 parB Yersinia pestis CO92 partitioning protein B NP_395412.1 67988 R 214092 CDS NP_395413.1 16082859 1172822 complement(68956..70161) 1 NC_003134.1 partitioning protein A 70161 parA 1172822 parA Yersinia pestis CO92 partitioning protein A NP_395413.1 68956 R 214092 CDS NP_395414.1 16082860 1172821 70463..70690 1 NC_003134.1 hypothetical protein 70690 1172821 YPMT1.68A Yersinia pestis CO92 hypothetical protein NP_395414.1 70463 D 214092 CDS NP_395415.1 16082861 1172823 70690..71016 1 NC_003134.1 hypothetical protein 71016 1172823 YPMT1.69 Yersinia pestis CO92 hypothetical protein NP_395415.1 70690 D 214092 CDS NP_395416.1 16082862 1172824 71216..71836 1 NC_003134.1 putative resolvase 71836 1172824 YPMT1.70 Yersinia pestis CO92 putative resolvase NP_395416.1 71216 D 214092 CDS NP_395417.1 16082863 1172825 71857..72843 1 NC_003134.1 hypothetical protein 72843 1172825 YPMT1.71 Yersinia pestis CO92 hypothetical protein NP_395417.1 71857 D 214092 CDS NP_395418.1 16082864 1172826 complement(72866..73141) 1 NC_003134.1 hypothetical protein 73141 1172826 YPMT1.72c Yersinia pestis CO92 hypothetical protein NP_395418.1 72866 R 214092 CDS NP_395419.1 16082865 1172827 73881..74369 1 NC_003134.1 putative phospholipase D 74369 1172827 YPMT1.73 Yersinia pestis CO92 putative phospholipase D NP_395419.1 73881 D 214092 CDS NP_395420.2 40787870 1172828 74447..76210 1 NC_003134.1 toxin protein 76210 1172828 YPMT1.74 Yersinia pestis CO92 toxin protein NP_395420.2 74447 D 214092 CDS NP_395421.1 16082867 1172829 complement(76455..76925) 1 NC_003134.1 reverse transcriptase 76925 1172829 YPMT1.75c Yersinia pestis CO92 reverse transcriptase NP_395421.1 76455 R 214092 CDS NP_395422.1 16082868 1172830 76996..77304 1 NC_003134.1 hypothetical protein 77304 1172830 YPMT1.76 Yersinia pestis CO92 hypothetical protein NP_395422.1 76996 D 214092 CDS NP_395423.1 16082869 1172831 77219..77590 1 NC_003134.1 hypothetical protein 77590 1172831 YPMT1.76A Yersinia pestis CO92 hypothetical protein NP_395423.1 77219 D 214092 CDS NP_395425.1 16082871 1172834 complement(78286..79308) 1 NC_003134.1 transposase 79308 1172834 YPMT1.79c Yersinia pestis CO92 transposase NP_395425.1 78286 R 214092 CDS NP_395426.1 16082872 1172835 complement(79777..80985) 1 NC_003134.1 putative transposase 80985 1172835 YPMT1.80c Yersinia pestis CO92 putative transposase NP_395426.1 79777 R 214092 CDS NP_395427.1 16082873 1172836 complement(81334..82257) 1 NC_003134.1 putative F1 operon positive regulatory protein 82257 1172836 YPMT1.81c Yersinia pestis CO92 putative F1 operon positive regulatory protein NP_395427.1 81334 R 214092 CDS NP_395428.1 16082874 1172837 82567..83343 1 NC_003134.1 putative F1 chaperone protein 83343 caf1M 1172837 caf1M Yersinia pestis CO92 putative F1 chaperone protein NP_395428.1 82567 D 214092 CDS NP_395429.1 16082875 1172838 83368..85869 1 NC_003134.1 putative F1 capsule anchoring protein 85869 caf1A 1172838 caf1A Yersinia pestis CO92 putative F1 capsule anchoring protein NP_395429.1 83368 D 214092 CDS NP_395430.1 16082876 1172839 85950..86462 1 NC_003134.1 F1 capsule antigen 86462 1172839 YPMT1.84 Yersinia pestis CO92 F1 capsule antigen NP_395430.1 85950 D 214092 CDS NP_395432.1 16082878 1172842 complement(88320..88706) 1 NC_003134.1 hypothetical protein 88706 1172842 YPMT1.86c Yersinia pestis CO92 hypothetical protein NP_395432.1 88320 R 214092 CDS NP_395433.1 16082879 1172841 88969..89181 1 NC_003134.1 hypothetical protein 89181 1172841 YPMT1.86A Yersinia pestis CO92 hypothetical protein NP_395433.1 88969 D 214092 CDS NP_395434.1 16082880 1172843 89291..91657 1 NC_003134.1 porphyrin biosynthetic protein 91657 cobT 1172843 cobT Yersinia pestis CO92 porphyrin biosynthetic protein NP_395434.1 89291 D 214092 CDS NP_395435.1 16082881 1172844 91754..92989 1 NC_003134.1 porphyrin biosynthetic protein 92989 cobS 1172844 cobS Yersinia pestis CO92 porphyrin biosynthetic protein NP_395435.1 91754 D 214092 CDS YP_002345097.1 218927222 1172846 complement(271..711) 1 NC_003143.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 711 1172846 YPO0001 Yersinia pestis CO92 flavodoxin YP_002345097.1 271 R 214092 CDS YP_002345098.1 218927223 1172849 complement(804..1265) 1 NC_003143.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 1265 asnC 1172849 asnC Yersinia pestis CO92 DNA-binding transcriptional regulator AsnC YP_002345098.1 804 R 214092 CDS YP_002345099.1 218927224 1172850 1435..2427 1 NC_003143.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 2427 asnA 1172850 asnA Yersinia pestis CO92 asparagine synthetase AsnA YP_002345099.1 1435 D 214092 CDS YP_002345100.1 218927225 1172847 complement(2526..3992) 1 NC_003143.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 3992 yieM 1172847 yieM Yersinia pestis CO92 hypothetical protein YP_002345100.1 2526 R 214092 CDS YP_002345101.1 218927226 1172848 complement(3996..5549) 1 NC_003143.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 5549 1172848 YPO0005 Yersinia pestis CO92 regulatory ATPase RavA YP_002345101.1 3996 R 214092 CDS YP_002345102.1 218927227 1172851 5823..7691 1 NC_003143.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 7691 trkD 1172851 trkD Yersinia pestis CO92 potassium transport protein Kup YP_002345102.1 5823 D 214092 CDS YP_002345103.1 218927228 1172852 7896..8315 1 NC_003143.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 8315 1172852 YPO0007 Yersinia pestis CO92 D-ribose pyranase YP_002345103.1 7896 D 214092 CDS YP_002345104.1 218927229 1172853 8366..9292 1 NC_003143.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 9292 rbsK 1172853 rbsK Yersinia pestis CO92 ribokinase YP_002345104.1 8366 D 214092 CDS YP_002345105.1 218927230 1172854 complement(9512..10936) 1 NC_003143.1 membrane transport protein 10936 1172854 YPO0009 Yersinia pestis CO92 membrane transport protein YP_002345105.1 9512 R 214092 CDS YP_002345106.1 218927231 1172855 complement(11016..11705) 1 NC_003143.1 GntR family transcriptional regulator 11705 1172855 YPO0010 Yersinia pestis CO92 GntR family transcriptional regulator YP_002345106.1 11016 R 214092 CDS YP_008479675.1 537470124 16744735 complement(12074..12259) 1 NC_003143.1 hypothetical protein 12259 16744735 YPO0010a Yersinia pestis CO92 hypothetical protein YP_008479675.1 12074 R 214092 CDS YP_002345107.1 218927232 1172860 17906..19114 1 NC_003143.1 transposase for the IS285 insertion element 19114 1172860 YPO0011 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002345107.1 17906 D 214092 CDS YP_002345108.1 218927233 1172861 complement(19172..19702) 1 NC_003143.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein B 19702 mobB 1172861 mobB Yersinia pestis CO92 molybdopterin-guanine dinucleotide biosynthesis protein B YP_002345108.1 19172 R 214092 CDS YP_002345109.1 218927234 1172862 complement(19702..20343) 1 NC_003143.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 20343 mobA 1172862 mobA Yersinia pestis CO92 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_002345109.1 19702 R 214092 CDS YP_002345110.1 218927235 1172863 20443..20712 1 NC_003143.1 hypothetical protein 20712 1172863 YPO0013a Yersinia pestis CO92 hypothetical protein YP_002345110.1 20443 D 214092 CDS YP_002345111.1 218927236 1172864 20792..21778 1 NC_003143.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 21778 1172864 YPO0014 Yersinia pestis CO92 serine/threonine protein kinase YP_002345111.1 20792 D 214092 CDS YP_002345112.1 218927237 1172865 21806..22429 1 NC_003143.1 periplasmic protein disulfide isomerase I 22429 dsbA 1172865 dsbA Yersinia pestis CO92 periplasmic protein disulfide isomerase I YP_002345112.1 21806 D 214092 CDS YP_002345113.1 218927238 1172866 22921..25719 1 NC_003143.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 25719 polA 1172866 polA Yersinia pestis CO92 DNA polymerase I YP_002345113.1 22921 D 214092 CDS YP_002345114.1 218927239 1172868 26128..26586 1 NC_003143.1 transposase for the IS1541 insertion element 26586 tnp 1172868 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345114.1 26128 D 214092 CDS YP_002345115.1 218927240 1172869 complement(26838..27488) 1 NC_003143.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 27488 engB 1172869 engB Yersinia pestis CO92 ribosome biogenesis GTP-binding protein YsxC YP_002345115.1 26838 R 214092 CDS YP_002345116.1 218927241 1172870 28233..28799 1 NC_003143.1 hypothetical protein 28799 1172870 YPO0020 Yersinia pestis CO92 hypothetical protein YP_002345116.1 28233 D 214092 CDS YP_002345117.1 218927242 1172871 28982..30355 1 NC_003143.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 30355 hemN 1172871 hemN Yersinia pestis CO92 coproporphyrinogen III oxidase YP_002345117.1 28982 D 214092 CDS YP_002345118.1 218927243 1172872 complement(30409..31821) 1 NC_003143.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 31821 glnG 1172872 glnG Yersinia pestis CO92 nitrogen regulation protein NR(I) YP_002345118.1 30409 R 214092 CDS YP_002345119.1 218927244 1172873 complement(31829..32878) 1 NC_003143.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 32878 glnL 1172873 glnL Yersinia pestis CO92 nitrogen regulation protein NR(II) YP_002345119.1 31829 R 214092 CDS YP_002345120.1 218927245 1172874 complement(33131..34540) 1 NC_003143.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 34540 glnA 1172874 glnA Yersinia pestis CO92 glutamine synthetase YP_002345120.1 33131 R 214092 CDS YP_002345122.1 218927247 1172876 35102..36925 1 NC_003143.1 GTPase 36925 bipA 1172876 bipA Yersinia pestis CO92 GTPase YP_002345122.1 35102 D 214092 CDS YP_002345123.1 218927248 1172877 37247..37837 1 NC_003143.1 phosphatase 37837 1172877 YPO0027 Yersinia pestis CO92 phosphatase YP_002345123.1 37247 D 214092 CDS YP_002345124.1 218927249 1172878 37934..38818 1 NC_003143.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 38818 rbn 1172878 rbn Yersinia pestis CO92 ribonuclease BN YP_002345124.1 37934 D 214092 CDS YP_002345125.1 218927250 1172879 38825..39262 1 NC_003143.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 39262 1172879 YPO0029 Yersinia pestis CO92 D-tyrosyl-tRNA(Tyr) deacylase YP_002345125.1 38825 D 214092 CDS YP_002345126.1 218927251 1172880 complement(39336..40118) 1 NC_003143.1 transposase/IS protein 40118 1172880 YPO0030 Yersinia pestis CO92 transposase/IS protein YP_002345126.1 39336 R 214092 CDS YP_002345127.1 218927252 1172881 complement(40115..41137) 1 NC_003143.1 transposase for insertion sequence IS100 41137 y1093 1172881 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002345127.1 40115 R 214092 CDS YP_002345128.1 218927253 1172882 41407..42330 1 NC_003143.1 hypothetical protein 42330 1172882 YPO0032 Yersinia pestis CO92 hypothetical protein YP_002345128.1 41407 D 214092 CDS YP_002345129.1 218927254 1172883 complement(42465..44174) 1 NC_003143.1 hypothetical protein 44174 1172883 YPO0033 Yersinia pestis CO92 hypothetical protein YP_002345129.1 42465 R 214092 CDS YP_002345130.1 218927255 1172884 complement(44322..45707) 1 NC_003143.1 membrane permease 45707 1172884 YPO0034 Yersinia pestis CO92 membrane permease YP_002345130.1 44322 R 214092 CDS YP_002345131.1 218927256 1172885 45945..47159 1 NC_003143.1 sodium/glutamate symport carrier protein 47159 gltC 1172885 gltC Yersinia pestis CO92 sodium/glutamate symport carrier protein YP_002345131.1 45945 D 214092 CDS YP_002345132.1 218927257 1172886 complement(47525..49606) 1 NC_003143.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 49606 recG 1172886 recG Yersinia pestis CO92 ATP-dependent DNA helicase RecG YP_002345132.1 47525 R 214092 CDS YP_002345133.1 218927258 1172887 complement(49607..50299) 1 NC_003143.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 50299 trmH 1172887 trmH Yersinia pestis CO92 tRNA guanosine-2'-O-methyltransferase YP_002345133.1 49607 R 214092 CDS YP_002345134.1 218927259 1172888 complement(50305..52413) 1 NC_003143.1 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 52413 spoT 1172888 spoT Yersinia pestis CO92 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_002345134.1 50305 R 214092 CDS YP_002345135.1 218927260 1172889 complement(52433..52708) 1 NC_003143.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 52708 rpoZ 1172889 rpoZ Yersinia pestis CO92 DNA-directed RNA polymerase subunit omega YP_002345135.1 52433 R 214092 CDS YP_002345136.1 218927261 1172890 complement(52763..53386) 1 NC_003143.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 53386 gmk 1172890 gmk Yersinia pestis CO92 guanylate kinase YP_002345136.1 52763 R 214092 CDS YP_002345137.1 218927262 1172891 53787..55490 1 NC_003143.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+; NAD-dependent DNA ligase LigB 55490 ligB 1172891 ligB Yersinia pestis CO92 NAD-dependent DNA ligase LigB YP_002345137.1 53787 D 214092 CDS YP_002345138.1 218927263 1172892 complement(55503..56126) 1 NC_003143.1 hypothetical protein 56126 1172892 YPO0042 Yersinia pestis CO92 hypothetical protein YP_002345138.1 55503 R 214092 CDS YP_002345139.1 218927264 1172893 complement(56529..57392) 1 NC_003143.1 hypothetical protein 57392 1172893 YPO0043 Yersinia pestis CO92 hypothetical protein YP_002345139.1 56529 R 214092 CDS YP_002345140.1 218927265 1172894 57519..58235 1 NC_003143.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 58235 rph 1172894 rph Yersinia pestis CO92 ribonuclease PH YP_002345140.1 57519 D 214092 CDS YP_002345141.1 218927266 1172895 58402..59049 1 NC_003143.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 59049 pyrE 1172895 pyrE Yersinia pestis CO92 orotate phosphoribosyltransferase YP_002345141.1 58402 D 214092 CDS YP_002345142.1 218927267 1172896 complement(59184..59780) 1 NC_003143.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 59780 slmA 1172896 slmA Yersinia pestis CO92 nucleoid occlusion protein YP_002345142.1 59184 R 214092 CDS YP_002345143.1 218927268 1172897 complement(59902..60357) 1 NC_003143.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 60357 dut 1172897 dut Yersinia pestis CO92 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002345143.1 59902 R 214092 CDS YP_002345144.1 218927269 1172898 complement(60338..61552) 1 NC_003143.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 61552 dfp 1172898 dfp Yersinia pestis CO92 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_002345144.1 60338 R 214092 CDS YP_002345145.1 218927270 1172899 61749..62417 1 NC_003143.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 62417 radC 1172899 radC Yersinia pestis CO92 DNA repair protein RadC YP_002345145.1 61749 D 214092 CDS YP_002345146.1 218927271 1172900 62680..62916 1 NC_003143.1 required for 70S ribosome assembly; 50S ribosomal protein L28 62916 rpmB 1172900 rpmB Yersinia pestis CO92 50S ribosomal protein L28 YP_002345146.1 62680 D 214092 CDS YP_002345147.1 218927272 1172901 62928..63095 1 NC_003143.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 63095 rpmG 1172901 rpmG Yersinia pestis CO92 50S ribosomal protein L33 YP_002345147.1 62928 D 214092 CDS YP_002345148.1 218927273 1172902 63178..63987 1 NC_003143.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 63987 mutM 1172902 mutM Yersinia pestis CO92 formamidopyrimidine-DNA glycosylase YP_002345148.1 63178 D 214092 CDS YP_002345149.1 218927274 1172903 complement(63993..64472) 1 NC_003143.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 64472 coaD 1172903 coaD Yersinia pestis CO92 phosphopantetheine adenylyltransferase YP_002345149.1 63993 R 214092 CDS YP_002345150.1 218927275 1172904 complement(64469..65251) 1 NC_003143.1 lipopolysaccharide core biosynthesis glycosyl transferase 65251 kdtX 1172904 kdtX Yersinia pestis CO92 lipopolysaccharide core biosynthesis glycosyl transferase YP_002345150.1 64469 R 214092 CDS YP_002345151.1 218927276 1172905 complement(65252..66529) 1 NC_003143.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 66529 kdtA 1172905 kdtA Yersinia pestis CO92 3-deoxy-D-manno-octulosonic-acid transferase YP_002345151.1 65252 R 214092 CDS YP_002345152.1 218927277 1172906 complement(66949..67914) 1 NC_003143.1 ADP-heptose:LPS heptosyl transferase I 67914 rfaC 1172906 rfaC Yersinia pestis CO92 ADP-heptose:LPS heptosyl transferase I YP_002345152.1 66949 R 214092 CDS YP_002345153.1 218927278 1172907 complement(67914..68978) 1 NC_003143.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose:LPS heptosyltransferase II 68978 rfaF 1172907 rfaF Yersinia pestis CO92 ADP-heptose:LPS heptosyltransferase II YP_002345153.1 67914 R 214092 CDS YP_002345154.1 218927279 1172908 complement(69009..69941) 1 NC_003143.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 69941 rfaD 1172908 rfaD Yersinia pestis CO92 ADP-L-glycero-D-manno-heptose-6-epimerase YP_002345154.1 69009 R 214092 CDS YP_002345155.1 218927280 1172909 70187..71398 1 NC_003143.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase 71398 kbl 1172909 kbl Yersinia pestis CO92 2-amino-3-ketobutyrate CoA ligase YP_002345155.1 70187 D 214092 CDS YP_002345156.1 218927281 1172910 71408..72433 1 NC_003143.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 72433 tdh 1172910 tdh Yersinia pestis CO92 L-threonine 3-dehydrogenase YP_002345156.1 71408 D 214092 CDS YP_002345157.1 218927282 1172912 complement(73529..74881) 1 NC_003143.1 hypothetical protein 74881 1172912 YPO0063 Yersinia pestis CO92 hypothetical protein YP_002345157.1 73529 R 214092 CDS YP_002345158.1 218927283 1172913 complement(74909..76456) 1 NC_003143.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 76456 1172913 YPO0064 Yersinia pestis CO92 phosphoglyceromutase YP_002345158.1 74909 R 214092 CDS YP_002345159.1 218927284 1172914 76853..77287 1 NC_003143.1 hypothetical protein 77287 1172914 YPO0065 Yersinia pestis CO92 hypothetical protein YP_002345159.1 76853 D 214092 CDS YP_002345160.1 218927285 1172915 77406..77654 1 NC_003143.1 glutaredoxin 3 77654 grxC 1172915 grxC Yersinia pestis CO92 glutaredoxin 3 YP_002345160.1 77406 D 214092 CDS YP_002345161.1 218927286 1172916 77742..78218 1 NC_003143.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 78218 secB 1172916 secB Yersinia pestis CO92 preprotein translocase subunit SecB YP_002345161.1 77742 D 214092 CDS YP_002345162.1 218927287 1172917 78218..79237 1 NC_003143.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 79237 gpsA 1172917 gpsA Yersinia pestis CO92 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002345162.1 78218 D 214092 CDS YP_002345163.1 218927288 1172918 79297..79437 1 NC_003143.1 No significant database hits; hypothetical protein 79437 1172918 YPO0069 Yersinia pestis CO92 hypothetical protein YP_002345163.1 79297 D 214092 CDS YP_002345164.1 218927289 1172919 79503..80324 1 NC_003143.1 catalyzes the O-acetylation of serine; serine acetyltransferase 80324 cysE 1172919 cysE Yersinia pestis CO92 serine acetyltransferase YP_002345164.1 79503 D 214092 CDS YP_002345165.1 218927290 1172920 complement(80447..80935) 1 NC_003143.1 methyltransferase 80935 1172920 YPO0071 Yersinia pestis CO92 methyltransferase YP_002345165.1 80447 R 214092 CDS YP_002345166.1 218927291 1172921 81124..82188 1 NC_003143.1 bifunctional regulatory protein/DNA repair protein 82188 1172921 YPO0072 Yersinia pestis CO92 bifunctional regulatory protein/DNA repair protein YP_002345166.1 81124 D 214092 CDS YP_002345167.1 218927292 1172922 complement(82237..83613) 1 NC_003143.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 83613 cpxA 1172922 cpxA Yersinia pestis CO92 two-component sensor protein YP_002345167.1 82237 R 214092 CDS YP_002345168.1 218927293 1172923 complement(83610..84308) 1 NC_003143.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 84308 cpxR 1172923 cpxR Yersinia pestis CO92 DNA-binding transcriptional regulator CpxR YP_002345168.1 83610 R 214092 CDS YP_002345169.1 218927294 1172924 84482..84970 1 NC_003143.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; periplasmic stress adaptor protein CpxP 84970 cpxP 1172924 cpxP Yersinia pestis CO92 periplasmic stress adaptor protein CpxP YP_002345169.1 84482 D 214092 CDS YP_002345170.1 218927295 1172925 85648..86607 1 NC_003143.1 hypothetical protein 86607 1172925 YPO0076 Yersinia pestis CO92 hypothetical protein YP_002345170.1 85648 D 214092 CDS YP_002345171.1 218927296 1172926 87169..88071 1 NC_003143.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 88071 fieF 1172926 fieF Yersinia pestis CO92 ferrous iron efflux protein F YP_002345171.1 87169 D 214092 CDS YP_002345172.1 218927297 1172927 88289..89272 1 NC_003143.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 89272 pfkA 1172927 pfkA Yersinia pestis CO92 6-phosphofructokinase YP_002345172.1 88289 D 214092 CDS YP_002345173.1 218927298 1172928 89493..90482 1 NC_003143.1 sulfate transporter subunit 90482 sbp1 1172928 sbp1 Yersinia pestis CO92 sulfate transporter subunit YP_002345173.1 89493 D 214092 CDS YP_002345174.1 218927299 1172929 complement(90732..91550) 1 NC_003143.1 hypothetical protein 91550 1172929 YPO0080 Yersinia pestis CO92 hypothetical protein YP_002345174.1 90732 R 214092 CDS YP_002345175.1 218927300 1172930 complement(91626..93053) 1 NC_003143.1 membrane transport protein 93053 1172930 YPO0081 Yersinia pestis CO92 membrane transport protein YP_002345175.1 91626 R 214092 CDS YP_002345176.1 218927301 1172931 complement(93119..93832) 1 NC_003143.1 hypothetical protein 93832 1172931 YPO0082 Yersinia pestis CO92 hypothetical protein YP_002345176.1 93119 R 214092 CDS YP_002345177.2 537470125 1172932 complement(93829..94566) 1 NC_003143.1 hypothetical protein 94566 1172932 YPO0083 Yersinia pestis CO92 hypothetical protein YP_002345177.2 93829 R 214092 CDS YP_002345178.1 218927303 1172933 94892..95938 1 NC_003143.1 transcriptional regulator 95938 1172933 YPO0084 Yersinia pestis CO92 transcriptional regulator YP_002345178.1 94892 D 214092 CDS YP_002345179.1 218927304 1172934 complement(96170..96937) 1 NC_003143.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 96937 tpiA 1172934 tpiA Yersinia pestis CO92 triosephosphate isomerase YP_002345179.1 96170 R 214092 CDS YP_002345180.1 218927305 1172935 complement(97066..97701) 1 NC_003143.1 hypothetical protein 97701 1172935 YPO0086 Yersinia pestis CO92 hypothetical protein YP_002345180.1 97066 R 214092 CDS YP_002345181.1 218927306 1172936 97849..98283 1 NC_003143.1 hypothetical protein 98283 1172936 YPO0087 Yersinia pestis CO92 hypothetical protein YP_002345181.1 97849 D 214092 CDS YP_002345182.1 218927307 1172937 complement(98624..99370) 1 NC_003143.1 ferredoxin-NADP reductase 99370 fpr 1172937 fpr Yersinia pestis CO92 ferredoxin-NADP reductase YP_002345182.1 98624 R 214092 CDS YP_002345183.1 218927308 1172940 complement(101532..102380) 1 NC_003143.1 glycerol uptake facilitator protein 102380 glpF 1172940 glpF Yersinia pestis CO92 glycerol uptake facilitator protein YP_002345183.1 101532 R 214092 CDS YP_002345185.1 218927310 1172942 103008..103247 1 NC_003143.1 hypothetical protein 103247 1172942 YPO0093 Yersinia pestis CO92 hypothetical protein YP_002345185.1 103008 D 214092 CDS YP_002345186.1 218927311 1172943 complement(103455..103913) 1 NC_003143.1 transposase for the IS1541 insertion element 103913 tnp 1172943 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345186.1 103455 R 214092 CDS YP_002345187.1 218927312 1172945 complement(105645..106427) 1 NC_003143.1 transposase/IS protein 106427 1172945 YPO0096 Yersinia pestis CO92 transposase/IS protein YP_002345187.1 105645 R 214092 CDS YP_002345188.1 218927313 1172946 complement(106424..107446) 1 NC_003143.1 transposase for insertion sequence IS100 107446 y1093 1172946 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002345188.1 106424 R 214092 CDS YP_002345189.1 218927314 1172947 complement(108358..109593) 1 NC_003143.1 hypothetical protein 109593 1172947 YPO0099 Yersinia pestis CO92 hypothetical protein YP_002345189.1 108358 R 214092 CDS YP_002345190.1 218927315 1172948 109863..110102 1 NC_003143.1 no significant database hits; hypothetical protein 110102 1172948 YPO0100 Yersinia pestis CO92 hypothetical protein YP_002345190.1 109863 D 214092 CDS YP_002345191.1 218927316 1172949 110277..110426 1 NC_003143.1 Doubtful CDS with no significant database hits; hypothetical protein 110426 1172949 YPO0101 Yersinia pestis CO92 hypothetical protein YP_002345191.1 110277 D 214092 CDS YP_002345192.1 218927317 1172950 110732..111316 1 NC_003143.1 No significant database hits; hypothetical protein 111316 1172950 YPO0102 Yersinia pestis CO92 hypothetical protein YP_002345192.1 110732 D 214092 CDS YP_002345193.1 218927318 1172951 complement(111433..111918) 1 NC_003143.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 111918 menG 1172951 menG Yersinia pestis CO92 ribonuclease activity regulator protein RraA YP_002345193.1 111433 R 214092 CDS YP_002345194.1 218927319 1172952 complement(112060..112977) 1 NC_003143.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 112977 menA 1172952 menA Yersinia pestis CO92 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_002345194.1 112060 R 214092 CDS YP_002345195.1 218927320 1172953 complement(113213..114544) 1 NC_003143.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 114544 hslU 1172953 hslU Yersinia pestis CO92 ATP-dependent protease ATP-binding subunit HslU YP_002345195.1 113213 R 214092 CDS YP_002345196.1 218927321 1172954 complement(114615..115139) 1 NC_003143.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 115139 hslV 1172954 hslV Yersinia pestis CO92 ATP-dependent protease peptidase subunit YP_002345196.1 114615 R 214092 CDS YP_002345197.1 218927322 1172955 complement(115239..116084) 1 NC_003143.1 cell division protein FtsN 116084 ftsN 1172955 ftsN Yersinia pestis CO92 cell division protein FtsN YP_002345197.1 115239 R 214092 CDS YP_002345198.1 218927323 1172956 complement(116150..117178) 1 NC_003143.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 117178 cytR 1172956 cytR Yersinia pestis CO92 DNA-binding transcriptional regulator CytR YP_002345198.1 116150 R 214092 CDS YP_002345199.1 218927324 1172957 complement(117531..119729) 1 NC_003143.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 119729 priA 1172957 priA Yersinia pestis CO92 primosome assembly protein PriA YP_002345199.1 117531 R 214092 CDS YP_002345200.1 218927325 1172958 119972..120187 1 NC_003143.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 120187 rpmE 1172958 rpmE Yersinia pestis CO92 50S ribosomal protein L31 YP_002345200.1 119972 D 214092 CDS YP_002345201.1 218927326 1172959 complement(120748..121203) 1 NC_003143.1 hypothetical protein 121203 1172959 YPO0112 Yersinia pestis CO92 hypothetical protein YP_002345201.1 120748 R 214092 CDS YP_002345203.1 218927328 1172961 complement(121552..121869) 1 NC_003143.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 121869 metJ 1172961 metJ Yersinia pestis CO92 transcriptional repressor protein MetJ YP_002345203.1 121552 R 214092 CDS YP_002345204.1 218927329 1172963 123409..125844 1 NC_003143.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 125844 metL 1172963 metL Yersinia pestis CO92 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_002345204.1 123409 D 214092 CDS YP_002345205.1 218927330 1172964 126077..126961 1 NC_003143.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 126961 metF 1172964 metF Yersinia pestis CO92 5,10-methylenetetrahydrofolate reductase YP_002345205.1 126077 D 214092 CDS YP_002345206.1 218927331 1172965 complement(127139..127924) 1 NC_003143.1 transposase for insertion sequence IS1661 127924 1172965 YPO0118 Yersinia pestis CO92 transposase for insertion sequence IS1661 YP_002345206.1 127139 R 214092 CDS YP_002345207.2 537470126 1172966 complement(127978..128622) 1 NC_003143.1 insertion element DNA-binding protein 128622 1172966 YPO0119 Yersinia pestis CO92 insertion element DNA-binding protein YP_002345207.2 127978 R 214092 CDS YP_002345208.1 218927333 1172967 complement(128686..129444) 1 NC_003143.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 129444 glpR 1172967 glpR Yersinia pestis CO92 DNA-binding transcriptional repressor GlpR YP_002345208.1 128686 R 214092 CDS YP_002345209.1 218927334 1172968 complement(129479..130315) 1 NC_003143.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 130315 glpG 1172968 glpG Yersinia pestis CO92 intramembrane serine protease GlpG YP_002345209.1 129479 R 214092 CDS YP_002345210.1 218927335 1172969 complement(130333..130662) 1 NC_003143.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 130662 glpE 1172969 glpE Yersinia pestis CO92 thiosulfate sulfurtransferase YP_002345210.1 130333 R 214092 CDS YP_002345211.1 218927336 1172970 complement(131037..133748) 1 NC_003143.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 133748 malT 1172970 malT Yersinia pestis CO92 transcriptional regulator MalT YP_002345211.1 131037 R 214092 CDS YP_002345212.1 218927337 1172972 136483..138579 1 NC_003143.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 138579 malQ 1172972 malQ Yersinia pestis CO92 4-alpha-glucanotransferase YP_002345212.1 136483 D 214092 CDS YP_002345213.1 218927338 1172973 complement(138908..139483) 1 NC_003143.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 139483 1172973 YPO0127 Yersinia pestis CO92 DNA uptake protein YP_002345213.1 138908 R 214092 CDS YP_002345214.1 218927339 1172974 complement(139543..140244) 1 NC_003143.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 140244 1172974 YPO0128 Yersinia pestis CO92 gluconate periplasmic binding protein YP_002345214.1 139543 R 214092 CDS YP_002345215.1 218927340 1172975 140331..141107 1 NC_003143.1 biotin biosynthesis protein 141107 bioH 1172975 bioH Yersinia pestis CO92 biotin biosynthesis protein YP_002345215.1 140331 D 214092 CDS YP_002345216.1 218927341 1172976 141277..141546 1 NC_003143.1 hypothetical protein 141546 1172976 YPO0130 Yersinia pestis CO92 hypothetical protein YP_002345216.1 141277 D 214092 CDS YP_002345217.1 218927342 1172977 complement(141684..141941) 1 NC_003143.1 hypothetical protein 141941 1172977 YPO0131 Yersinia pestis CO92 hypothetical protein YP_002345217.1 141684 R 214092 CDS YP_002345218.1 218927343 1172978 complement(141977..144292) 1 NC_003143.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 144292 feoB 1172978 feoB Yersinia pestis CO92 ferrous iron transport protein B YP_002345218.1 141977 R 214092 CDS YP_002345219.1 218927344 1172979 complement(144384..144611) 1 NC_003143.1 ferrous iron transport protein A 144611 feoA 1172979 feoA Yersinia pestis CO92 ferrous iron transport protein A YP_002345219.1 144384 R 214092 CDS YP_002345220.1 218927345 1172980 complement(145135..147510) 1 NC_003143.1 hypothetical protein 147510 1172980 YPO0134 Yersinia pestis CO92 hypothetical protein YP_002345220.1 145135 R 214092 CDS YP_002345221.1 218927346 1172981 148044..148559 1 NC_003143.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 148559 greB 1172981 greB Yersinia pestis CO92 transcription elongation factor GreB YP_002345221.1 148044 D 214092 CDS YP_002345222.1 218927347 1172982 148695..149414 1 NC_003143.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 149414 ompR 1172982 ompR Yersinia pestis CO92 osmolarity response regulator YP_002345222.1 148695 D 214092 CDS YP_002345223.1 218927348 1172983 149411..150763 1 NC_003143.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 150763 envZ 1172983 envZ Yersinia pestis CO92 osmolarity sensor protein YP_002345223.1 149411 D 214092 CDS YP_002345224.1 218927349 1172984 complement(150898..152517) 1 NC_003143.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 152517 pckA 1172984 pckA Yersinia pestis CO92 phosphoenolpyruvate carboxykinase YP_002345224.1 150898 R 214092 CDS YP_002345225.1 218927350 1172985 complement(152714..153595) 1 NC_003143.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 153595 hslO 1172985 hslO Yersinia pestis CO92 heat shock protein 33 YP_002345225.1 152714 R 214092 CDS YP_002345226.1 218927351 1172986 complement(153758..154165) 1 NC_003143.1 heat shock protein 15 154165 hslR 1172986 hslR Yersinia pestis CO92 heat shock protein 15 YP_002345226.1 153758 R 214092 CDS YP_002345227.1 218927352 1172987 complement(154194..154874) 1 NC_003143.1 hypothetical protein 154874 1172987 YPO0141 Yersinia pestis CO92 hypothetical protein YP_002345227.1 154194 R 214092 CDS YP_002345228.1 218927353 1172988 complement(155018..157165) 1 NC_003143.1 hypothetical protein 157165 1172988 YPO0142 Yersinia pestis CO92 hypothetical protein YP_002345228.1 155018 R 214092 CDS YP_002345230.1 218927355 1172990 157752..158297 1 NC_003143.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 158297 nudE 1172990 nudE Yersinia pestis CO92 ADP-ribose diphosphatase NudE YP_002345230.1 157752 D 214092 CDS YP_002345231.1 218927356 1172991 complement(158433..160988) 1 NC_003143.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 160988 mrcA 1172991 mrcA Yersinia pestis CO92 peptidoglycan synthetase YP_002345231.1 158433 R 214092 CDS YP_002345232.1 218927357 1172992 161063..162004 1 NC_003143.1 hypothetical protein 162004 1172992 YPO0146 Yersinia pestis CO92 hypothetical protein YP_002345232.1 161063 D 214092 CDS YP_002345233.1 218927358 1172993 162004..162609 1 NC_003143.1 hypothetical protein 162609 1172993 YPO0147 Yersinia pestis CO92 hypothetical protein YP_002345233.1 162004 D 214092 CDS YP_002345234.1 218927359 1172994 162602..163183 1 NC_003143.1 No significant database hits; hypothetical protein 163183 1172994 YPO0148 Yersinia pestis CO92 hypothetical protein YP_002345234.1 162602 D 214092 CDS YP_002345235.1 218927360 1172995 163209..163577 1 NC_003143.1 Doubtful CDS, no significant database hits; hypothetical protein 163577 1172995 YPO0149 Yersinia pestis CO92 hypothetical protein YP_002345235.1 163209 D 214092 CDS YP_002345236.1 218927361 1172996 164004..165128 1 NC_003143.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; porin 165128 hofQ 1172996 hofQ Yersinia pestis CO92 porin YP_002345236.1 164004 D 214092 CDS YP_002345237.1 218927362 1172997 165477..165998 1 NC_003143.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 165998 aroK 1172997 aroK Yersinia pestis CO92 shikimate kinase I YP_002345237.1 165477 D 214092 CDS YP_002345238.1 218927363 1172998 166055..167143 1 NC_003143.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 167143 aroB 1172998 aroB Yersinia pestis CO92 3-dehydroquinate synthase YP_002345238.1 166055 D 214092 CDS YP_002345239.1 218927364 1172999 167397..168386 1 NC_003143.1 hypothetical protein 168386 1172999 YPO0153 Yersinia pestis CO92 hypothetical protein YP_002345239.1 167397 D 214092 CDS YP_002345240.1 218927365 1173000 168470..169285 1 NC_003143.1 DNA adenine methylase 169285 dam 1173000 dam Yersinia pestis CO92 DNA adenine methylase YP_002345240.1 168470 D 214092 CDS YP_002345241.1 218927366 1173001 169588..170265 1 NC_003143.1 ribulose-phosphate 3-epimerase 170265 rpe 1173001 rpe Yersinia pestis CO92 ribulose-phosphate 3-epimerase YP_002345241.1 169588 D 214092 CDS YP_002345242.1 218927367 1173002 170258..170956 1 NC_003143.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 170956 gph 1173002 gph Yersinia pestis CO92 phosphoglycolate phosphatase YP_002345242.1 170258 D 214092 CDS YP_002345243.1 218927368 1173003 170958..171998 1 NC_003143.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 171998 trpS 1173003 trpS Yersinia pestis CO92 tryptophanyl-tRNA synthetase YP_002345243.1 170958 D 214092 CDS YP_002345244.1 218927369 1173004 complement(172153..173565) 1 NC_003143.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 173565 cysG 1173004 cysG Yersinia pestis CO92 siroheme synthase YP_002345244.1 172153 R 214092 CDS YP_002345245.1 218927370 1173005 complement(173653..174459) 1 NC_003143.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 174459 nirC 1173005 nirC Yersinia pestis CO92 nitrite transporter NirC YP_002345245.1 173653 R 214092 CDS YP_002345246.1 218927371 1173006 complement(174662..174988) 1 NC_003143.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 174988 nirD 1173006 nirD Yersinia pestis CO92 nitrite reductase small subunit YP_002345246.1 174662 R 214092 CDS YP_002345247.1 218927372 1173007 complement(174985..177531) 1 NC_003143.1 nitrite reductase 177531 nirB 1173007 nirB Yersinia pestis CO92 nitrite reductase YP_002345247.1 174985 R 214092 CDS YP_002345248.1 218927373 1173008 177841..179151 1 NC_003143.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 179151 codA 1173008 codA Yersinia pestis CO92 cytosine deaminase YP_002345248.1 177841 D 214092 CDS YP_002345249.1 218927374 1173009 complement(179236..180420) 1 NC_003143.1 hypothetical protein 180420 1173009 YPO0163 Yersinia pestis CO92 hypothetical protein YP_002345249.1 179236 R 214092 CDS YP_002345250.1 218927375 1173010 180906..182966 1 NC_003143.1 membrane receptor protein 182966 1173010 YPO0164 Yersinia pestis CO92 membrane receptor protein YP_002345250.1 180906 D 214092 CDS YP_002345251.1 218927376 1173011 complement(183067..184053) 1 NC_003143.1 LacI family transcriptional regulator 184053 1173011 YPO0165 Yersinia pestis CO92 LacI family transcriptional regulator YP_002345251.1 183067 R 214092 CDS YP_002345252.1 218927377 1173012 complement(184302..185615) 1 NC_003143.1 glycosyl hydrolase 185615 1173012 YPO0166 Yersinia pestis CO92 glycosyl hydrolase YP_002345252.1 184302 R 214092 CDS YP_002345253.1 218927378 1173013 186131..186700 1 NC_003143.1 peptidyl-prolyl cis-trans isomerase A 186700 ppiA 1173013 ppiA Yersinia pestis CO92 peptidyl-prolyl cis-trans isomerase A YP_002345253.1 186131 D 214092 CDS YP_002345254.1 218927379 1173014 187026..188567 1 NC_003143.1 hypothetical protein 188567 1173014 YPO0168 Yersinia pestis CO92 hypothetical protein YP_002345254.1 187026 D 214092 CDS YP_002345255.1 218927380 1173015 188810..189385 1 NC_003143.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 189385 pabA 1173015 pabA Yersinia pestis CO92 para-aminobenzoate synthase component II YP_002345255.1 188810 D 214092 CDS YP_002345256.1 218927381 1173017 190137..191159 1 NC_003143.1 transposase for insertion sequence IS100 191159 y1093 1173017 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002345256.1 190137 D 214092 CDS YP_002345257.1 218927382 1173018 191156..191938 1 NC_003143.1 transposase/IS protein 191938 1173018 YPO0172 Yersinia pestis CO92 transposase/IS protein YP_002345257.1 191156 D 214092 CDS YP_002345258.1 218927383 1173019 complement(192920..195040) 1 NC_003143.1 hypothetical protein 195040 1173019 YPO0174 Yersinia pestis CO92 hypothetical protein YP_002345258.1 192920 R 214092 CDS YP_002345259.1 218927384 1173020 complement(195126..195758) 1 NC_003143.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 195758 crp 1173020 crp Yersinia pestis CO92 cAMP-regulatory protein YP_002345259.1 195126 R 214092 CDS YP_002345260.1 218927385 1173021 196094..196501 1 NC_003143.1 hypothetical protein 196501 1173021 YPO0176 Yersinia pestis CO92 hypothetical protein YP_002345260.1 196094 D 214092 CDS YP_002345261.1 218927386 1173022 196573..197004 1 NC_003143.1 No significant database hits. CDS DNA has a low G+C content (34%).; hypothetical protein 197004 1173022 YPO0177 Yersinia pestis CO92 hypothetical protein YP_002345261.1 196573 D 214092 CDS YP_002345262.1 218927387 1173023 complement(197182..198051) 1 NC_003143.1 phosphoribulokinase 1 198051 prk 1173023 prk Yersinia pestis CO92 phosphoribulokinase 1 YP_002345262.1 197182 R 214092 CDS YP_002345263.1 218927388 1173024 complement(198200..198436) 1 NC_003143.1 hypothetical protein 198436 1173024 YPO0179 Yersinia pestis CO92 hypothetical protein YP_002345263.1 198200 R 214092 CDS YP_002345264.1 218927389 1173025 complement(198433..199413) 1 NC_003143.1 hydrolase 199413 1173025 YPO0180 Yersinia pestis CO92 hydrolase YP_002345264.1 198433 R 214092 CDS YP_002345265.1 218927390 1173026 199515..200117 1 NC_003143.1 ABC transporter 200117 1173026 YPO0181 Yersinia pestis CO92 ABC transporter YP_002345265.1 199515 D 214092 CDS YP_002345266.1 218927391 1173027 200320..201381 1 NC_003143.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 201381 tauA 1173027 tauA Yersinia pestis CO92 taurine transporter substrate binding subunit YP_002345266.1 200320 D 214092 CDS YP_002345267.1 218927392 1173028 201390..202157 1 NC_003143.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding protein 202157 tauB 1173028 tauB Yersinia pestis CO92 taurine transporter ATP-binding protein YP_002345267.1 201390 D 214092 CDS YP_002345268.1 218927393 1173029 202154..203008 1 NC_003143.1 taurine transporter subunit 203008 tauC 1173029 tauC Yersinia pestis CO92 taurine transporter subunit YP_002345268.1 202154 D 214092 CDS YP_002345269.1 218927394 1173030 203005..203853 1 NC_003143.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 203853 tauD 1173030 tauD Yersinia pestis CO92 taurine dioxygenase YP_002345269.1 203005 D 214092 CDS YP_002345270.1 218927395 1173031 complement(203866..204846) 1 NC_003143.1 sugar transferase 204846 1173031 YPO0186 Yersinia pestis CO92 sugar transferase YP_002345270.1 203866 R 214092 CDS YP_002345271.1 218927396 1173032 complement(204939..205928) 1 NC_003143.1 glycosyl transferase 205928 1173032 YPO0187 Yersinia pestis CO92 glycosyl transferase YP_002345271.1 204939 R 214092 CDS YP_002345272.1 218927397 1173034 208229..208780 1 NC_003143.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 208780 1173034 YPO0190 Yersinia pestis CO92 glutathione-regulated potassium-efflux system ancillary protein KefG YP_002345272.1 208229 D 214092 CDS YP_002345273.1 218927398 1173035 208784..210592 1 NC_003143.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 210592 kefB 1173035 kefB Yersinia pestis CO92 glutathione-regulated potassium-efflux system protein KefB YP_002345273.1 208784 D 214092 CDS YP_002345274.1 218927399 1173036 210608..210829 1 NC_003143.1 hypothetical protein 210829 1173036 YPO0192 Yersinia pestis CO92 hypothetical protein YP_002345274.1 210608 D 214092 CDS YP_002345275.1 218927400 1173037 210924..211511 1 NC_003143.1 rotamase; FKBP-type peptidylprolyl isomerase 211511 slyD 1173037 slyD Yersinia pestis CO92 FKBP-type peptidylprolyl isomerase YP_002345275.1 210924 D 214092 CDS YP_002345276.1 218927401 1173038 complement(211732..211950) 1 NC_003143.1 hypothetical protein 211950 1173038 YPO0194 Yersinia pestis CO92 hypothetical protein YP_002345276.1 211732 R 214092 CDS YP_002345277.1 218927402 1173039 212265..213065 1 NC_003143.1 rotamase; FKBP-type peptidylprolyl isomerase 213065 fkpA 1173039 fkpA Yersinia pestis CO92 FKBP-type peptidylprolyl isomerase YP_002345277.1 212265 D 214092 CDS YP_002345278.1 218927403 1173040 213307..214041 1 NC_003143.1 DNA-binding protein 214041 1173040 YPO0196 Yersinia pestis CO92 DNA-binding protein YP_002345278.1 213307 D 214092 CDS YP_002345279.1 218927404 1173041 214041..214436 1 NC_003143.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 214436 1173041 YPO0197 Yersinia pestis CO92 sulfur transfer complex subunit TusD YP_002345279.1 214041 D 214092 CDS YP_002345280.1 218927405 1173042 214436..214801 1 NC_003143.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 214801 1173042 YPO0198 Yersinia pestis CO92 sulfur relay protein TusC YP_002345280.1 214436 D 214092 CDS YP_002345281.1 218927406 1173043 214821..215108 1 NC_003143.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 215108 1173043 YPO0199 Yersinia pestis CO92 sulfur transfer complex subunit TusB YP_002345281.1 214821 D 214092 CDS YP_002345282.1 218927407 1173044 215246..215620 1 NC_003143.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 215620 rpsL 1173044 rpsL Yersinia pestis CO92 30S ribosomal protein S12 YP_002345282.1 215246 D 214092 CDS YP_002345283.1 218927408 1173045 215717..216187 1 NC_003143.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 216187 rpsG 1173045 rpsG Yersinia pestis CO92 30S ribosomal protein S7 YP_002345283.1 215717 D 214092 CDS YP_002345284.1 218927409 1173046 216281..218389 1 NC_003143.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 218389 fusA 1173046 fusA Yersinia pestis CO92 elongation factor G YP_002345284.1 216281 D 214092 CDS YP_002345285.1 218927410 1173047 218462..219646 1 NC_003143.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 219646 tuf 1173047 tuf Yersinia pestis CO92 elongation factor Tu YP_002345285.1 218462 D 214092 CDS YP_002345286.1 218927411 1173048 219849..220307 1 NC_003143.1 transposase for the IS1541 insertion element 220307 tnp 1173048 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345286.1 219849 D 214092 CDS YP_002345287.1 218927412 1173049 220495..220689 1 NC_003143.1 bacterioferritin-associated ferredoxin 220689 bfd 1173049 bfd Yersinia pestis CO92 bacterioferritin-associated ferredoxin YP_002345287.1 220495 D 214092 CDS YP_002345288.1 218927413 1173050 220768..221241 1 NC_003143.1 iron storage protein; bacterioferritin 221241 bfr 1173050 bfr Yersinia pestis CO92 bacterioferritin YP_002345288.1 220768 D 214092 CDS YP_002345289.1 218927414 1173051 221655..221966 1 NC_003143.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 221966 rpsJ 1173051 rpsJ Yersinia pestis CO92 30S ribosomal protein S10 YP_002345289.1 221655 D 214092 CDS YP_002345290.1 218927415 1173052 221999..222628 1 NC_003143.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 222628 rplC 1173052 rplC Yersinia pestis CO92 50S ribosomal protein L3 YP_002345290.1 221999 D 214092 CDS YP_002345291.1 218927416 1173053 222645..223250 1 NC_003143.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 223250 rplD 1173053 rplD Yersinia pestis CO92 50S ribosomal protein L4 YP_002345291.1 222645 D 214092 CDS YP_002345292.1 218927417 1173054 223247..223549 1 NC_003143.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 223549 rplW 1173054 rplW Yersinia pestis CO92 50S ribosomal protein L23 YP_002345292.1 223247 D 214092 CDS YP_002345293.1 218927418 1173055 223566..224390 1 NC_003143.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 224390 rplB 1173055 rplB Yersinia pestis CO92 50S ribosomal protein L2 YP_002345293.1 223566 D 214092 CDS YP_002345294.1 218927419 1173056 224405..224683 1 NC_003143.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 224683 rpsS 1173056 rpsS Yersinia pestis CO92 30S ribosomal protein S19 YP_002345294.1 224405 D 214092 CDS YP_002345295.1 218927420 1173057 224698..225030 1 NC_003143.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 225030 rplV 1173057 rplV Yersinia pestis CO92 50S ribosomal protein L22 YP_002345295.1 224698 D 214092 CDS YP_002345296.1 218927421 1173058 225048..225746 1 NC_003143.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 225746 rpsC 1173058 rpsC Yersinia pestis CO92 30S ribosomal protein S3 YP_002345296.1 225048 D 214092 CDS YP_002345297.1 218927422 1173059 225759..226169 1 NC_003143.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 226169 rplP 1173059 rplP Yersinia pestis CO92 50S ribosomal protein L16 YP_002345297.1 225759 D 214092 CDS YP_002345298.1 218927423 1173060 226169..226360 1 NC_003143.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 226360 rpmC 1173060 rpmC Yersinia pestis CO92 50S ribosomal protein L29 YP_002345298.1 226169 D 214092 CDS YP_002345299.1 218927424 1173061 226360..226614 1 NC_003143.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 226614 rpsQ 1173061 rpsQ Yersinia pestis CO92 30S ribosomal protein S17 YP_002345299.1 226360 D 214092 CDS YP_002345300.1 218927425 1173062 226795..227166 1 NC_003143.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 227166 rplN 1173062 rplN Yersinia pestis CO92 50S ribosomal protein L14 YP_002345300.1 226795 D 214092 CDS YP_002345301.1 218927426 1173063 227177..227491 1 NC_003143.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 227491 rplX 1173063 rplX Yersinia pestis CO92 50S ribosomal protein L24 YP_002345301.1 227177 D 214092 CDS YP_002345302.1 218927427 1173064 227506..228045 1 NC_003143.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 228045 rplE 1173064 rplE Yersinia pestis CO92 50S ribosomal protein L5 YP_002345302.1 227506 D 214092 CDS YP_002345303.1 218927428 1173065 228059..228364 1 NC_003143.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 228364 rpsN 1173065 rpsN Yersinia pestis CO92 30S ribosomal protein S14 YP_002345303.1 228059 D 214092 CDS YP_002345304.1 218927429 1173066 228398..228790 1 NC_003143.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 228790 rpsH 1173066 rpsH Yersinia pestis CO92 30S ribosomal protein S8 YP_002345304.1 228398 D 214092 CDS YP_002345305.1 218927430 1173067 228805..229338 1 NC_003143.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 229338 rplF 1173067 rplF Yersinia pestis CO92 50S ribosomal protein L6 YP_002345305.1 228805 D 214092 CDS YP_002345306.1 218927431 1173068 229348..229701 1 NC_003143.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 229701 rplR 1173068 rplR Yersinia pestis CO92 50S ribosomal protein L18 YP_002345306.1 229348 D 214092 CDS YP_002345307.1 218927432 1173069 229716..230219 1 NC_003143.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 230219 rpsE 1173069 rpsE Yersinia pestis CO92 30S ribosomal protein S5 YP_002345307.1 229716 D 214092 CDS YP_002345308.1 218927433 1173070 230222..230401 1 NC_003143.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 230401 rpmD 1173070 rpmD Yersinia pestis CO92 50S ribosomal protein L30 YP_002345308.1 230222 D 214092 CDS YP_002345309.1 218927434 1173071 230405..230839 1 NC_003143.1 late assembly protein; 50S ribosomal protein L15 230839 rplO 1173071 rplO Yersinia pestis CO92 50S ribosomal protein L15 YP_002345309.1 230405 D 214092 CDS YP_002345310.1 218927435 1173072 230847..232178 1 NC_003143.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 232178 secY 1173072 secY Yersinia pestis CO92 preprotein translocase subunit SecY YP_002345310.1 230847 D 214092 CDS YP_002345311.1 218927436 1173073 232212..232328 1 NC_003143.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 232328 rpmJ 1173073 rpmJ Yersinia pestis CO92 50S ribosomal protein L36 YP_002345311.1 232212 D 214092 CDS YP_002345312.1 218927437 1173074 232476..232832 1 NC_003143.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 232832 rpsM 1173074 rpsM Yersinia pestis CO92 30S ribosomal protein S13 YP_002345312.1 232476 D 214092 CDS YP_002345313.1 218927438 1173075 232849..233238 1 NC_003143.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 233238 rpsK 1173075 rpsK Yersinia pestis CO92 30S ribosomal protein S11 YP_002345313.1 232849 D 214092 CDS YP_002345314.1 218927439 1173076 233269..233889 1 NC_003143.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 233889 rpsD 1173076 rpsD Yersinia pestis CO92 30S ribosomal protein S4 YP_002345314.1 233269 D 214092 CDS YP_002345315.1 218927440 1173077 233915..234904 1 NC_003143.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 234904 rpoA 1173077 rpoA Yersinia pestis CO92 DNA-directed RNA polymerase subunit alpha YP_002345315.1 233915 D 214092 CDS YP_002345316.1 218927441 1173078 234945..235334 1 NC_003143.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 235334 rplQ 1173078 rplQ Yersinia pestis CO92 50S ribosomal protein L17 YP_002345316.1 234945 D 214092 CDS YP_002345317.1 218927442 1173079 235781..236206 1 NC_003143.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 236206 zntR 1173079 zntR Yersinia pestis CO92 zinc-responsive transcriptional regulator YP_002345317.1 235781 D 214092 CDS YP_002345318.1 218927443 1173080 236294..236494 1 NC_003143.1 hypothetical protein 236494 1173080 YPO0237 Yersinia pestis CO92 hypothetical protein YP_002345318.1 236294 D 214092 CDS YP_002345319.1 218927444 1173081 complement(236604..237017) 1 NC_003143.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 237017 mscL 1173081 mscL Yersinia pestis CO92 large-conductance mechanosensitive channel YP_002345319.1 236604 R 214092 CDS YP_002345320.1 218927445 1173082 complement(237156..238532) 1 NC_003143.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 238532 trkA 1173082 trkA Yersinia pestis CO92 potassium transporter peripheral membrane component YP_002345320.1 237156 R 214092 CDS YP_002345321.1 218927446 1173083 complement(238588..239877) 1 NC_003143.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase GidB 239877 1173083 YPO0240 Yersinia pestis CO92 16S rRNA methyltransferase GidB YP_002345321.1 238588 R 214092 CDS YP_002345322.1 218927447 1173084 complement(239971..240918) 1 NC_003143.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 240918 fmt 1173084 fmt Yersinia pestis CO92 methionyl-tRNA formyltransferase YP_002345322.1 239971 R 214092 CDS YP_002345323.1 218927448 1173085 complement(240943..241455) 1 NC_003143.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 241455 def 1173085 def Yersinia pestis CO92 peptide deformylase YP_002345323.1 240943 R 214092 CDS YP_002345324.1 218927449 1173086 241590..242711 1 NC_003143.1 DNA protecting protein DprA 242711 1173086 YPO0243 Yersinia pestis CO92 DNA protecting protein DprA YP_002345324.1 241590 D 214092 CDS YP_002345325.1 218927450 1173087 242719..243156 1 NC_003143.1 hypothetical protein 243156 1173087 YPO0244 Yersinia pestis CO92 hypothetical protein YP_002345325.1 242719 D 214092 CDS YP_002345326.1 218927451 1173088 243197..243736 1 NC_003143.1 DNA-binding protein 243736 1173088 YPO0245 Yersinia pestis CO92 DNA-binding protein YP_002345326.1 243197 D 214092 CDS YP_002345327.1 218927452 1173089 243738..244310 1 NC_003143.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor 244310 1173089 YPO0245a Yersinia pestis CO92 ribosome maturation factor YP_002345327.1 243738 D 214092 CDS YP_002345328.1 218927453 1173090 244319..245140 1 NC_003143.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 245140 aroE 1173090 aroE Yersinia pestis CO92 shikimate 5-dehydrogenase YP_002345328.1 244319 D 214092 CDS YP_008479676.1 537470127 1173091 complement(245195..245776) 1 NC_003143.1 transferase 245776 1173091 YPO0247 Yersinia pestis CO92 transferase YP_008479676.1 245195 R 214092 CDS YP_002345329.1 218927454 1173092 complement(245792..246574) 1 NC_003143.1 transposase/IS protein 246574 1173092 YPO0248 Yersinia pestis CO92 transposase/IS protein YP_002345329.1 245792 R 214092 CDS YP_002345330.1 218927455 1173093 complement(246571..247593) 1 NC_003143.1 transposase for insertion sequence IS100 247593 y1093 1173093 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002345330.1 246571 R 214092 CDS YP_008479677.1 537470128 1173094 247646..248638 1 NC_003143.1 hydrolase 248638 1173094 YPO0250 Yersinia pestis CO92 hydrolase YP_008479677.1 247646 D 214092 CDS YP_002345331.1 218927456 1173095 complement(248712..250367) 1 NC_003143.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 250367 actP 1173095 actP Yersinia pestis CO92 acetate permease YP_002345331.1 248712 R 214092 CDS YP_002345332.1 218927457 1173096 complement(250364..250675) 1 NC_003143.1 hypothetical protein 250675 1173096 YPO0252 Yersinia pestis CO92 hypothetical protein YP_002345332.1 250364 R 214092 CDS YP_002345333.1 218927458 1173097 complement(250732..252690) 1 NC_003143.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 252690 acs 1173097 acs Yersinia pestis CO92 acetyl-CoA synthetase YP_002345333.1 250732 R 214092 CDS YP_002345334.1 218927459 1173098 253545..254861 1 NC_003143.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 254861 gltP 1173098 gltP Yersinia pestis CO92 glutamate/aspartate:proton symporter YP_002345334.1 253545 D 214092 CDS YP_002345335.1 218927460 1173099 complement(255039..255671) 1 NC_003143.1 two-component response regulator 255671 1173099 YPO0255 Yersinia pestis CO92 two-component response regulator YP_002345335.1 255039 R 214092 CDS YP_002345336.1 218927461 1173100 complement(255684..258503) 1 NC_003143.1 two-component sensor/regulator 258503 1173100 YPO0256 Yersinia pestis CO92 two-component sensor/regulator YP_002345336.1 255684 R 214092 CDS YP_002345337.1 218927462 1173101 258675..260246 1 NC_003143.1 type III secretion protein 260246 1173101 YPO0257 Yersinia pestis CO92 type III secretion protein YP_002345337.1 258675 D 214092 CDS YP_002345338.1 218927463 1173102 260248..261462 1 NC_003143.1 type-III secretion protein 261462 1173102 YPO0258 Yersinia pestis CO92 type-III secretion protein YP_002345338.1 260248 D 214092 CDS YP_002345339.1 218927464 1173103 261481..261702 1 NC_003143.1 type III secretion apparatus 261702 1173103 YPO0259 Yersinia pestis CO92 type III secretion apparatus YP_002345339.1 261481 D 214092 CDS YP_002345341.1 218927466 1173105 262506..262721 1 NC_003143.1 type III secretion apparatus 262721 1173105 YPO0260a Yersinia pestis CO92 type III secretion apparatus YP_002345341.1 262506 D 214092 CDS YP_002345342.1 218927467 1173106 262718..262966 1 NC_003143.1 type III secretion apparatus 262966 1173106 YPO0261 Yersinia pestis CO92 type III secretion apparatus YP_002345342.1 262718 D 214092 CDS YP_002345343.1 218927468 1173107 263064..263315 1 NC_003143.1 type III secretion apparatus 263315 1173107 YPO0262 Yersinia pestis CO92 type III secretion apparatus YP_002345343.1 263064 D 214092 CDS YP_002345344.1 218927469 1173108 263312..264043 1 NC_003143.1 type III secretion system apparatus lipoprotein 264043 1173108 YPO0263 Yersinia pestis CO92 type III secretion system apparatus lipoprotein YP_002345344.1 263312 D 214092 CDS YP_002345345.1 218927470 1173109 264218..264811 1 NC_003143.1 hypothetical protein 264811 1173109 YPO0264 Yersinia pestis CO92 hypothetical protein YP_002345345.1 264218 D 214092 CDS YP_002345346.1 218927471 1173110 264808..265455 1 NC_003143.1 type III secretion system apparatus protein 265455 1173110 YPO0265 Yersinia pestis CO92 type III secretion system apparatus protein YP_002345346.1 264808 D 214092 CDS YP_002345347.1 218927472 1173111 265448..267496 1 NC_003143.1 with SsaC forms part of a protein export system across the inner and outer cell membranes; part of the Salmonella pathogenicity island 2; part of the type III secretion system; secretion system apparatus protein SsaV 267496 1173111 YPO0266 Yersinia pestis CO92 secretion system apparatus protein SsaV YP_002345347.1 265448 D 214092 CDS YP_002345348.1 218927473 1173112 267483..268820 1 NC_003143.1 type III secretion system ATPase 268820 1173112 YPO0267 Yersinia pestis CO92 type III secretion system ATPase YP_002345348.1 267483 D 214092 CDS YP_002345349.1 218927474 1173113 268817..269218 1 NC_003143.1 type III secretion system apparatus protein 269218 1173113 YPO0268 Yersinia pestis CO92 type III secretion system apparatus protein YP_002345349.1 268817 D 214092 CDS YP_002345351.1 218927476 1173115 269617..270537 1 NC_003143.1 type III secretion system protein 270537 1173115 YPO0269 Yersinia pestis CO92 type III secretion system protein YP_002345351.1 269617 D 214092 CDS YP_002345352.1 218927477 1173116 270664..271314 1 NC_003143.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response; type III secretion system protein 271314 1173116 YPO0270 Yersinia pestis CO92 type III secretion system protein YP_002345352.1 270664 D 214092 CDS YP_002345353.1 218927478 1173117 271311..271604 1 NC_003143.1 type III secretion apparatus protein 271604 1173117 YPO0271 Yersinia pestis CO92 type III secretion apparatus protein YP_002345353.1 271311 D 214092 CDS YP_002345354.1 218927479 1173118 271606..272400 1 NC_003143.1 type III secretion apparatus protein 272400 1173118 YPO0272 Yersinia pestis CO92 type III secretion apparatus protein YP_002345354.1 271606 D 214092 CDS YP_002345355.1 218927480 1173119 272390..273457 1 NC_003143.1 member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli; secretion system apparatus protein SsaU 273457 1173119 YPO0273 Yersinia pestis CO92 secretion system apparatus protein SsaU YP_002345355.1 272390 D 214092 CDS YP_002345356.1 218927481 1173120 273840..275054 1 NC_003143.1 hypothetical protein 275054 1173120 YPO0274 Yersinia pestis CO92 hypothetical protein YP_002345356.1 273840 D 214092 CDS YP_002345357.1 218927482 1173121 275051..275320 1 NC_003143.1 hypothetical protein 275320 1173121 YPO0275 Yersinia pestis CO92 hypothetical protein YP_002345357.1 275051 D 214092 CDS YP_002345358.1 218927483 1173122 complement(275398..276384) 1 NC_003143.1 LysR family transcriptional regulator 276384 1173122 YPO0276 Yersinia pestis CO92 LysR family transcriptional regulator YP_002345358.1 275398 R 214092 CDS YP_002345359.1 218927484 1173123 276551..277837 1 NC_003143.1 transmembrane transport protein 277837 1173123 YPO0277 Yersinia pestis CO92 transmembrane transport protein YP_002345359.1 276551 D 214092 CDS YP_002345360.1 218927485 1173124 277883..279064 1 NC_003143.1 cystathionine beta-lyase 279064 metC 1173124 metC Yersinia pestis CO92 cystathionine beta-lyase YP_002345360.1 277883 D 214092 CDS YP_002345361.1 218927486 1173125 complement(279205..280005) 1 NC_003143.1 with HmuTU is involved in the transport of hemin; hemin importer ATP-binding subunit 280005 hmuV 1173125 hmuV Yersinia pestis CO92 hemin importer ATP-binding subunit YP_002345361.1 279205 R 214092 CDS YP_002345362.1 218927487 1173126 complement(279998..281002) 1 NC_003143.1 hemin transport system permease HmuU 281002 hmuU 1173126 hmuU Yersinia pestis CO92 hemin transport system permease HmuU YP_002345362.1 279998 R 214092 CDS YP_002345363.1 218927488 1173127 complement(280999..281838) 1 NC_003143.1 hemin-binding protein 281838 hmuT 1173127 hmuT Yersinia pestis CO92 hemin-binding protein YP_002345363.1 280999 R 214092 CDS YP_002345364.1 218927489 1173128 complement(281835..282872) 1 NC_003143.1 hemin transport protein 282872 hmuS 1173128 hmuS Yersinia pestis CO92 hemin transport protein YP_002345364.1 281835 R 214092 CDS YP_002345365.1 218927490 1173129 complement(282991..285021) 1 NC_003143.1 hemin receptor 285021 hmuR 1173129 hmuR Yersinia pestis CO92 hemin receptor YP_002345365.1 282991 R 214092 CDS YP_002345366.1 218927491 1173130 complement(285436..286086) 1 NC_003143.1 hypothetical protein 286086 1173130 YPO0284 Yersinia pestis CO92 hypothetical protein YP_002345366.1 285436 R 214092 CDS YP_002345367.1 218927492 1173131 complement(286120..286665) 1 NC_003143.1 hypothetical protein 286665 1173131 YPO0285 Yersinia pestis CO92 hypothetical protein YP_002345367.1 286120 R 214092 CDS YP_002345368.1 218927493 1173132 complement(286662..287975) 1 NC_003143.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 287975 1173132 YPO0286 Yersinia pestis CO92 coproporphyrinogen III oxidase YP_002345368.1 286662 R 214092 CDS YP_002345369.1 218927494 1173133 complement(288316..289116) 1 NC_003143.1 methylenetetrahydrofolate reductase 289116 1173133 YPO0287 Yersinia pestis CO92 methylenetetrahydrofolate reductase YP_002345369.1 288316 R 214092 CDS YP_002345370.1 218927495 1173134 complement(289431..289919) 1 NC_003143.1 hypothetical protein 289919 1173134 YPO0288 Yersinia pestis CO92 hypothetical protein YP_002345370.1 289431 R 214092 CDS YP_002345371.1 218927496 1173135 complement(290316..291275) 1 NC_003143.1 ATP/GTP-binding protein 291275 1173135 YPO0289 Yersinia pestis CO92 ATP/GTP-binding protein YP_002345371.1 290316 R 214092 CDS YP_002345372.1 218927497 1173136 complement(291275..292354) 1 NC_003143.1 hypothetical protein 292354 1173136 YPO0290 Yersinia pestis CO92 hypothetical protein YP_002345372.1 291275 R 214092 CDS YP_002345373.1 218927498 1173137 complement(292347..293159) 1 NC_003143.1 hypothetical protein 293159 1173137 YPO0291 Yersinia pestis CO92 hypothetical protein YP_002345373.1 292347 R 214092 CDS YP_002345374.1 218927499 1173138 complement(293152..294288) 1 NC_003143.1 hypothetical protein 294288 1173138 YPO0292 Yersinia pestis CO92 hypothetical protein YP_002345374.1 293152 R 214092 CDS YP_002345375.1 218927500 1173139 complement(294300..295361) 1 NC_003143.1 hypothetical protein 295361 1173139 YPO0293 Yersinia pestis CO92 hypothetical protein YP_002345375.1 294300 R 214092 CDS YP_002345376.1 218927501 1173140 295637..296230 1 NC_003143.1 tellurium resistance protein 296230 terZ 1173140 terZ Yersinia pestis CO92 tellurium resistance protein YP_002345376.1 295637 D 214092 CDS YP_002345377.2 284987066 1173141 296230..297414 1 NC_003143.1 tellurite resistance protein 297414 terA 1173141 terA Yersinia pestis CO92 tellurite resistance protein YP_002345377.2 296230 D 214092 CDS YP_002345378.1 218927503 1173142 297447..297902 1 NC_003143.1 tellurite resistance protein 297902 terB 1173142 terB Yersinia pestis CO92 tellurite resistance protein YP_002345378.1 297447 D 214092 CDS YP_002345379.1 218927504 1173143 297924..298961 1 NC_003143.1 tellurium resistance protein 298961 terC 1173143 terC Yersinia pestis CO92 tellurium resistance protein YP_002345379.1 297924 D 214092 CDS YP_002345380.1 218927505 1173144 299025..299603 1 NC_003143.1 tellurium resistance protein 299603 terD 1173144 terD Yersinia pestis CO92 tellurium resistance protein YP_002345380.1 299025 D 214092 CDS YP_002345381.1 218927506 1173145 299787..300362 1 NC_003143.1 tellurium resistance protein 300362 terE 1173145 terE Yersinia pestis CO92 tellurium resistance protein YP_002345381.1 299787 D 214092 CDS YP_002345382.1 218927507 1173146 300554..301012 1 NC_003143.1 transposase for the IS1541 insertion element 301012 tnp 1173146 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345382.1 300554 D 214092 CDS YP_002345383.1 218927508 1173147 301786..302424 1 NC_003143.1 hypothetical protein 302424 1173147 YPO0301 Yersinia pestis CO92 hypothetical protein YP_002345383.1 301786 D 214092 CDS YP_002345384.1 218927509 1173148 302675..305053 1 NC_003143.1 outer membrane fimbrial usher protein 305053 1173148 YPO0302 Yersinia pestis CO92 outer membrane fimbrial usher protein YP_002345384.1 302675 D 214092 CDS YP_002345385.1 218927510 1173149 305125..305868 1 NC_003143.1 member of the periplasmic pilus chaperone family of proteins; periplasmic chaperone protein 305868 1173149 YPO0303 Yersinia pestis CO92 periplasmic chaperone protein YP_002345385.1 305125 D 214092 CDS YP_002345386.1 218927511 1173150 305876..306133 1 NC_003143.1 No significant database hits; hypothetical protein 306133 1173150 YPO0304 Yersinia pestis CO92 hypothetical protein YP_002345386.1 305876 D 214092 CDS YP_002345387.1 218927512 1173151 307245..308645 1 NC_003143.1 No significant database hits; hypothetical protein 308645 1173151 YPO0306 Yersinia pestis CO92 hypothetical protein YP_002345387.1 307245 D 214092 CDS YP_002345389.1 218927514 1173153 309654..311711 1 NC_003143.1 oxidoreductase 311711 1173153 YPO0308 Yersinia pestis CO92 oxidoreductase YP_002345389.1 309654 D 214092 CDS YP_002345390.1 218927515 1173154 complement(312055..315771) 1 NC_003143.1 hypothetical protein 315771 1173154 YPO0309 Yersinia pestis CO92 hypothetical protein YP_002345390.1 312055 R 214092 CDS YP_002345391.1 218927516 1173155 316696..317220 1 NC_003143.1 catalyzes the formation of 4-hydroxybenzoate from chorismate; chorismate pyruvate lyase 317220 ubiC 1173155 ubiC Yersinia pestis CO92 chorismate pyruvate lyase YP_002345391.1 316696 D 214092 CDS YP_002345392.1 218927517 1173156 317386..318252 1 NC_003143.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 318252 ubiA 1173156 ubiA Yersinia pestis CO92 4-hydroxybenzoate octaprenyltransferase YP_002345392.1 317386 D 214092 CDS YP_002345393.1 218927518 1173157 complement(318433..320910) 1 NC_003143.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 320910 plsB 1173157 plsB Yersinia pestis CO92 glycerol-3-phosphate acyltransferase YP_002345393.1 318433 R 214092 CDS YP_002345394.1 218927519 1173158 321038..321409 1 NC_003143.1 diacylglycerol kinase 321409 1173158 YPO0313 Yersinia pestis CO92 diacylglycerol kinase YP_002345394.1 321038 D 214092 CDS YP_002345395.1 218927520 1173159 321534..322142 1 NC_003143.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 322142 lexA 1173159 lexA Yersinia pestis CO92 LexA repressor YP_002345395.1 321534 D 214092 CDS YP_002345396.1 218927521 1173160 complement(322302..322811) 1 NC_003143.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 322811 1173160 YPO0315 Yersinia pestis CO92 zinc uptake transcriptional repressor YP_002345396.1 322302 R 214092 CDS YP_002345397.1 218927522 1173161 323066..324103 1 NC_003143.1 tRNA-dihydrouridine synthase A 324103 1173161 YPO0316 Yersinia pestis CO92 tRNA-dihydrouridine synthase A YP_002345397.1 323066 D 214092 CDS YP_002345398.1 218927523 1173162 324619..324837 1 NC_003143.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 324837 pspG 1173162 pspG Yersinia pestis CO92 phage shock protein G YP_002345398.1 324619 D 214092 CDS YP_002345399.1 218927524 1173163 complement(325182..326165) 1 NC_003143.1 quinone oxidoreductase, NADPH-dependent 326165 qor 1173163 qor Yersinia pestis CO92 quinone oxidoreductase, NADPH-dependent YP_002345399.1 325182 R 214092 CDS YP_002345400.1 218927525 1173164 326497..327903 1 NC_003143.1 unwinds double stranded DNA; replicative DNA helicase 327903 dnaB 1173164 dnaB Yersinia pestis CO92 replicative DNA helicase YP_002345400.1 326497 D 214092 CDS YP_002345401.1 218927526 1173165 328000..329079 1 NC_003143.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 329079 alr 1173165 alr Yersinia pestis CO92 alanine racemase YP_002345401.1 328000 D 214092 CDS YP_002345402.1 218927527 1173166 329265..330458 1 NC_003143.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 330458 tyrB 1173166 tyrB Yersinia pestis CO92 aromatic amino acid aminotransferase YP_002345402.1 329265 D 214092 CDS YP_002345403.1 218927528 1173167 330985..331344 1 NC_003143.1 hypothetical protein 331344 1173167 YPO0323 Yersinia pestis CO92 hypothetical protein YP_002345403.1 330985 D 214092 CDS YP_002345404.1 218927529 1173168 complement(331437..334280) 1 NC_003143.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 334280 uvrA 1173168 uvrA Yersinia pestis CO92 excinuclease ABC subunit A YP_002345404.1 331437 R 214092 CDS YP_002345405.1 218927530 1173169 334738..335286 1 NC_003143.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 335286 ssb 1173169 ssb Yersinia pestis CO92 single-stranded DNA-binding protein YP_002345405.1 334738 D 214092 CDS YP_002345406.1 218927531 1173170 complement(335533..335847) 1 NC_003143.1 hypothetical protein 335847 1173170 YPO0326 Yersinia pestis CO92 hypothetical protein YP_002345406.1 335533 R 214092 CDS YP_002345407.1 218927532 1173171 complement(335861..337009) 1 NC_003143.1 alcohol dehydrogenase 337009 1173171 YPO0327 Yersinia pestis CO92 alcohol dehydrogenase YP_002345407.1 335861 R 214092 CDS YP_002345408.1 218927533 1173172 complement(337076..337900) 1 NC_003143.1 rhamnulose-1-phosphate aldolase 337900 rhaD 1173172 rhaD Yersinia pestis CO92 rhamnulose-1-phosphate aldolase YP_002345408.1 337076 R 214092 CDS YP_002345409.1 218927534 1173173 complement(337913..339169) 1 NC_003143.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 339169 rhaA 1173173 rhaA Yersinia pestis CO92 L-rhamnose isomerase YP_002345409.1 337913 R 214092 CDS YP_002345410.1 218927535 1173174 complement(339166..340623) 1 NC_003143.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 340623 rhaB 1173174 rhaB Yersinia pestis CO92 rhamnulokinase YP_002345410.1 339166 R 214092 CDS YP_002345411.1 218927536 1173175 340646..340828 1 NC_003143.1 No significant database hits; hypothetical protein 340828 1173175 YPO0331 Yersinia pestis CO92 hypothetical protein YP_002345411.1 340646 D 214092 CDS YP_002345412.1 218927537 1173176 341050..341871 1 NC_003143.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 341871 rhaS 1173176 rhaS Yersinia pestis CO92 transcriptional activator RhaS YP_002345412.1 341050 D 214092 CDS YP_002345413.1 218927538 1173177 342004..342876 1 NC_003143.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 342876 rhaR 1173177 rhaR Yersinia pestis CO92 transcriptional activator RhaR YP_002345413.1 342004 D 214092 CDS YP_002345414.1 218927539 1173178 complement(343025..344059) 1 NC_003143.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 344059 rhaT 1173178 rhaT Yersinia pestis CO92 rhamnose-proton symporter YP_002345414.1 343025 R 214092 CDS YP_002345416.1 218927541 1173181 complement(344915..345340) 1 NC_003143.1 No significant database hits; hypothetical protein 345340 1173181 YPO0337 Yersinia pestis CO92 hypothetical protein YP_002345416.1 344915 R 214092 CDS YP_002345417.1 218927542 1173182 345570..345737 1 NC_003143.1 No significant database hits; hypothetical protein 345737 1173182 YPO0338 Yersinia pestis CO92 hypothetical protein YP_002345417.1 345570 D 214092 CDS YP_002345418.1 218927543 1173183 345752..348322 1 NC_003143.1 enhancing factor 348322 1173183 YPO0339 Yersinia pestis CO92 enhancing factor YP_002345418.1 345752 D 214092 CDS YP_002345419.1 218927544 1173186 complement(348976..349551) 1 NC_003143.1 transcriptional regulator 349551 1173186 YPO0341 Yersinia pestis CO92 transcriptional regulator YP_002345419.1 348976 R 214092 CDS YP_002345420.1 218927545 1173187 349971..351986 1 NC_003143.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 351986 1173187 YPO0342 Yersinia pestis CO92 oxidoreductase Fe-S binding subunit YP_002345420.1 349971 D 214092 CDS YP_002345421.1 218927546 1173188 352009..352566 1 NC_003143.1 4Fe-4S ferredoxin 352566 hydN 1173188 hydN Yersinia pestis CO92 4Fe-4S ferredoxin YP_002345421.1 352009 D 214092 CDS YP_002345422.1 218927547 1173189 352589..354736 1 NC_003143.1 formate dehydrogenase H 354736 1173189 YPO0344 Yersinia pestis CO92 formate dehydrogenase H YP_002345422.1 352589 D 214092 CDS YP_002345423.1 218927548 1173190 complement(354798..356585) 1 NC_003143.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 356585 dipZ 1173190 dipZ Yersinia pestis CO92 thiol:disulfide interchange protein YP_002345423.1 354798 R 214092 CDS YP_002345424.1 218927549 1173191 complement(356561..356920) 1 NC_003143.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 356920 1173191 YPO0346 Yersinia pestis CO92 divalent-cation tolerance protein CutA YP_002345424.1 356561 R 214092 CDS YP_002345425.1 218927550 1173192 complement(357105..358406) 1 NC_003143.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 358406 dcuA 1173192 dcuA Yersinia pestis CO92 anaerobic C4-dicarboxylate transporter YP_002345425.1 357105 R 214092 CDS YP_002345426.1 218927551 1173193 complement(358526..359962) 1 NC_003143.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 359962 aspA 1173193 aspA Yersinia pestis CO92 aspartate ammonia-lyase YP_002345426.1 358526 R 214092 CDS YP_002345427.1 218927552 1173194 360410..360988 1 NC_003143.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 360988 fxsA 1173194 fxsA Yersinia pestis CO92 FxsA protein YP_002345427.1 360410 D 214092 CDS YP_002345428.1 218927553 1173195 361243..361536 1 NC_003143.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 361536 groES 1173195 groES Yersinia pestis CO92 co-chaperonin GroES YP_002345428.1 361243 D 214092 CDS YP_002345429.1 218927554 1173196 361583..363229 1 NC_003143.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 363229 groEL 1173196 groEL Yersinia pestis CO92 molecular chaperone GroEL YP_002345429.1 361583 D 214092 CDS YP_002345430.1 218927555 1173197 363865..364251 1 NC_003143.1 lipoprotein 364251 1173197 YPO0352 Yersinia pestis CO92 lipoprotein YP_002345430.1 363865 D 214092 CDS YP_002345431.1 218927556 1173198 complement(364536..365564) 1 NC_003143.1 hypothetical protein 365564 1173198 YPO0353 Yersinia pestis CO92 hypothetical protein YP_002345431.1 364536 R 214092 CDS YP_002345432.1 218927557 1173199 365600..366166 1 NC_003143.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 366166 efp 1173199 efp Yersinia pestis CO92 elongation factor P YP_002345432.1 365600 D 214092 CDS YP_002345433.1 218927558 1173200 366413..366727 1 NC_003143.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations; quaternary ammonium compound-resistance protein SugE 366727 sugE 1173200 sugE Yersinia pestis CO92 quaternary ammonium compound-resistance protein SugE YP_002345433.1 366413 D 214092 CDS YP_002345434.1 218927559 1173201 complement(366946..367404) 1 NC_003143.1 transposase for the IS1541 insertion element 367404 tnp 1173201 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345434.1 366946 R 214092 CDS YP_002345435.1 218927560 1173202 complement(367602..367958) 1 NC_003143.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 367958 frdD 1173202 frdD Yersinia pestis CO92 fumarate reductase subunit D YP_002345435.1 367602 R 214092 CDS YP_002345436.1 218927561 1173203 complement(367975..368367) 1 NC_003143.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 368367 frdC 1173203 frdC Yersinia pestis CO92 fumarate reductase subunit C YP_002345436.1 367975 R 214092 CDS YP_002345437.1 218927562 1173204 complement(368384..369118) 1 NC_003143.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 369118 frdB 1173204 frdB Yersinia pestis CO92 fumarate reductase iron-sulfur subunit YP_002345437.1 368384 R 214092 CDS YP_002345438.1 218927563 1173205 complement(369111..370934) 1 NC_003143.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 370934 frdA 1173205 frdA Yersinia pestis CO92 fumarate reductase flavoprotein subunit YP_002345438.1 369111 R 214092 CDS YP_002345440.1 218927565 1173207 371392..372369 1 NC_003143.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 372369 1173207 YPO0362 Yersinia pestis CO92 lysyl-tRNA synthetase YP_002345440.1 371392 D 214092 CDS YP_002345441.1 218927566 1173208 complement(372490..375849) 1 NC_003143.1 hypothetical protein 375849 1173208 YPO0363 Yersinia pestis CO92 hypothetical protein YP_002345441.1 372490 R 214092 CDS YP_002345442.1 218927567 1173209 complement(375873..376754) 1 NC_003143.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 376754 psd 1173209 psd Yersinia pestis CO92 phosphatidylserine decarboxylase YP_002345442.1 375873 R 214092 CDS YP_002345443.1 218927568 1173210 complement(377079..378131) 1 NC_003143.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 378131 1173210 YPO0365 Yersinia pestis CO92 ribosome-associated GTPase YP_002345443.1 377079 R 214092 CDS YP_002345444.1 218927569 1173211 378331..378876 1 NC_003143.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 378876 orn 1173211 orn Yersinia pestis CO92 oligoribonuclease YP_002345444.1 378331 D 214092 CDS YP_002345445.1 218927570 1173213 complement(379821..381056) 1 NC_003143.1 (Fe-S)-binding protein 381056 1173213 YPO0367 Yersinia pestis CO92 (Fe-S)-binding protein YP_002345445.1 379821 R 214092 CDS YP_002345446.1 218927571 1173214 381055..382569 1 NC_003143.1 hypothetical protein 382569 1173214 YPO0368 Yersinia pestis CO92 hypothetical protein YP_002345446.1 381055 D 214092 CDS YP_002345447.1 218927572 1173215 382580..383050 1 NC_003143.1 possibly involved in cell wall synthesis; ATPase 383050 1173215 YPO0369 Yersinia pestis CO92 ATPase YP_002345447.1 382580 D 214092 CDS YP_002345448.1 218927573 1173216 383190..384971 1 NC_003143.1 N-acetylmuramoyl-L-alanine amidase 384971 1173216 YPO0370 Yersinia pestis CO92 N-acetylmuramoyl-L-alanine amidase YP_002345448.1 383190 D 214092 CDS YP_002345449.1 218927574 1173217 384987..386894 1 NC_003143.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 386894 mutL 1173217 mutL Yersinia pestis CO92 DNA mismatch repair protein YP_002345449.1 384987 D 214092 CDS YP_002345450.1 218927575 1173218 386887..387828 1 NC_003143.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 387828 miaA 1173218 miaA Yersinia pestis CO92 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002345450.1 386887 D 214092 CDS YP_002345451.1 218927576 1173219 387944..388249 1 NC_003143.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 388249 hfq 1173219 hfq Yersinia pestis CO92 RNA-binding protein Hfq YP_002345451.1 387944 D 214092 CDS YP_002345452.1 218927577 1173220 388348..389634 1 NC_003143.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 389634 hflX 1173220 hflX Yersinia pestis CO92 GTPase HflX YP_002345452.1 388348 D 214092 CDS YP_002345453.1 218927578 1173221 389875..391134 1 NC_003143.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 391134 hflK 1173221 hflK Yersinia pestis CO92 FtsH protease regulator HflK YP_002345453.1 389875 D 214092 CDS YP_002345454.1 218927579 1173222 391138..392142 1 NC_003143.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 392142 hflC 1173222 hflC Yersinia pestis CO92 FtsH protease regulator HflC YP_002345454.1 391138 D 214092 CDS YP_002345455.1 218927580 1173223 392314..392514 1 NC_003143.1 hypothetical protein 392514 1173223 YPO0377 Yersinia pestis CO92 hypothetical protein YP_002345455.1 392314 D 214092 CDS YP_002345456.1 218927581 1173224 392614..393912 1 NC_003143.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 393912 purA 1173224 purA Yersinia pestis CO92 adenylosuccinate synthetase YP_002345456.1 392614 D 214092 CDS YP_002345457.1 218927582 1173225 394281..394706 1 NC_003143.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 394706 1173225 YPO0379 Yersinia pestis CO92 transcriptional repressor NsrR YP_002345457.1 394281 D 214092 CDS YP_002345458.1 218927583 1173226 394947..397481 1 NC_003143.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 397481 rnr 1173226 rnr Yersinia pestis CO92 exoribonuclease R YP_002345458.1 394947 D 214092 CDS YP_002345459.1 218927584 1173227 397600..398340 1 NC_003143.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 398340 1173227 YPO0381 Yersinia pestis CO92 23S rRNA (guanosine-2'-O-)-methyltransferase YP_002345459.1 397600 D 214092 CDS YP_002345460.1 218927585 1173228 398748..400391 1 NC_003143.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 400391 aidB 1173228 aidB Yersinia pestis CO92 isovaleryl CoA dehydrogenase YP_002345460.1 398748 D 214092 CDS YP_002345461.1 218927586 1173229 complement(400463..400774) 1 NC_003143.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A 400774 1173229 YPO0384 Yersinia pestis CO92 biofilm stress and motility protein A YP_002345461.1 400463 R 214092 CDS YP_002345462.1 218927587 1173230 complement(401114..401896) 1 NC_003143.1 transposase/IS protein 401896 1173230 YPO0385 Yersinia pestis CO92 transposase/IS protein YP_002345462.1 401114 R 214092 CDS YP_002345463.1 218927588 1173231 complement(401893..402915) 1 NC_003143.1 transposase for insertion sequence IS100 402915 y1093 1173231 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002345463.1 401893 R 214092 CDS YP_002345464.1 218927589 1173232 403049..405112 1 NC_003143.1 hypothetical protein 405112 1173232 YPO0387 Yersinia pestis CO92 hypothetical protein YP_002345464.1 403049 D 214092 CDS YP_002345465.1 218927590 1173233 405109..406425 1 NC_003143.1 hypothetical protein 406425 1173233 YPO0388 Yersinia pestis CO92 hypothetical protein YP_002345465.1 405109 D 214092 CDS YP_008853943.1 559797718 17699566 complement(407047..407310) 1 NC_003143.1 hypothetical protein 407310 17699566 YPO0392a Yersinia pestis CO92 hypothetical protein YP_008853943.1 407047 R 214092 CDS YP_002345468.1 218927593 1173236 407449..408774 1 NC_003143.1 modification methylase 408774 1173236 YPO0391 Yersinia pestis CO92 modification methylase YP_002345468.1 407449 D 214092 CDS YP_002345469.1 218927594 1173237 408824..409546 1 NC_003143.1 hypothetical protein 409546 1173237 YPO0392 Yersinia pestis CO92 hypothetical protein YP_002345469.1 408824 D 214092 CDS YP_002345470.1 218927595 1173238 409656..410891 1 NC_003143.1 hypothetical protein 410891 1173238 YPO0393 Yersinia pestis CO92 hypothetical protein YP_002345470.1 409656 D 214092 CDS YP_002345471.1 218927596 1173239 complement(411235..411522) 1 NC_003143.1 No significant database hits; hypothetical protein 411522 1173239 YPO0394 Yersinia pestis CO92 hypothetical protein YP_002345471.1 411235 R 214092 CDS YP_008479679.1 537470131 16744736 complement(411724..411921) 1 NC_003143.1 hypothetical protein 411921 16744736 YPO0394a Yersinia pestis CO92 hypothetical protein YP_008479679.1 411724 R 214092 CDS YP_002345473.1 218927598 1173241 412139..413551 1 NC_003143.1 hypothetical protein 413551 1173241 YPO0396 Yersinia pestis CO92 hypothetical protein YP_002345473.1 412139 D 214092 CDS YP_002345474.1 218927599 1173242 413548..414702 1 NC_003143.1 hypothetical protein 414702 1173242 YPO0397 Yersinia pestis CO92 hypothetical protein YP_002345474.1 413548 D 214092 CDS YP_002345475.1 218927600 1173243 complement(414848..415894) 1 NC_003143.1 M48 peptidase family protein 415894 1173243 YPO0398 Yersinia pestis CO92 M48 peptidase family protein YP_002345475.1 414848 R 214092 CDS YP_002345476.1 218927601 1173244 complement(415905..417101) 1 NC_003143.1 hypothetical protein 417101 1173244 YPO0399 Yersinia pestis CO92 hypothetical protein YP_002345476.1 415905 R 214092 CDS YP_002345477.1 218927602 1173245 417807..418343 1 NC_003143.1 No significant database hits; hypothetical protein 418343 1173245 YPO0400 Yersinia pestis CO92 hypothetical protein YP_002345477.1 417807 D 214092 CDS YP_002345478.1 218927603 1173246 418345..419220 1 NC_003143.1 transcriptional regulator 419220 1173246 YPO0401 Yersinia pestis CO92 transcriptional regulator YP_002345478.1 418345 D 214092 CDS YP_002345479.1 218927604 1173247 complement(419213..419557) 1 NC_003143.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; PTS system fructose-family transporter subunit IIB 419557 1173247 YPO0402 Yersinia pestis CO92 PTS system fructose-family transporter subunit IIB YP_002345479.1 419213 R 214092 CDS YP_002345480.1 218927605 1173248 complement(419650..419970) 1 NC_003143.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose family transporter subunit IIB 419970 1173248 YPO0403 Yersinia pestis CO92 PTS system fructose family transporter subunit IIB YP_002345480.1 419650 R 214092 CDS YP_002345481.1 218927606 1173249 complement(420311..421396) 1 NC_003143.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; PTS system fructose-family transporter subunit IIC 421396 1173249 YPO0404 Yersinia pestis CO92 PTS system fructose-family transporter subunit IIC YP_002345481.1 420311 R 214092 CDS YP_002345482.1 218927607 1173250 421758..424316 1 NC_003143.1 phosphoenolpyruvate-protein phosphotransferase 424316 1173250 YPO0405 Yersinia pestis CO92 phosphoenolpyruvate-protein phosphotransferase YP_002345482.1 421758 D 214092 CDS YP_002345483.1 218927608 1173251 complement(424378..424869) 1 NC_003143.1 hypothetical protein 424869 1173251 YPO0406 Yersinia pestis CO92 hypothetical protein YP_002345483.1 424378 R 214092 CDS YP_002345484.1 218927609 1173252 complement(425170..425460) 1 NC_003143.1 autoinducer-2 (AI-2) modifying protein LsrG 425460 1173252 YPO0407 Yersinia pestis CO92 autoinducer-2 (AI-2) modifying protein LsrG YP_002345484.1 425170 R 214092 CDS YP_002345485.1 218927610 1173253 complement(425524..426399) 1 NC_003143.1 aldolase 426399 1173253 YPO0408 Yersinia pestis CO92 aldolase YP_002345485.1 425524 R 214092 CDS YP_002345486.1 218927611 1173254 complement(426455..427474) 1 NC_003143.1 substrate-binding protein 427474 1173254 YPO0409 Yersinia pestis CO92 substrate-binding protein YP_002345486.1 426455 R 214092 CDS YP_002345487.1 218927612 1173255 complement(427540..428541) 1 NC_003143.1 ABC transporter permease 428541 1173255 YPO0410 Yersinia pestis CO92 ABC transporter permease YP_002345487.1 427540 R 214092 CDS YP_002345488.1 218927613 1173256 complement(428538..429593) 1 NC_003143.1 ABC transporter permease 429593 1173256 YPO0411 Yersinia pestis CO92 ABC transporter permease YP_002345488.1 428538 R 214092 CDS YP_002345489.1 218927614 1173257 complement(429587..431170) 1 NC_003143.1 ABC transporter ATP-binding protein 431170 1173257 YPO0412 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002345489.1 429587 R 214092 CDS YP_002345491.1 218927616 1173260 432673..434265 1 NC_003143.1 autoinducer-2 (AI-2) kinase 434265 1173260 YPO0415 Yersinia pestis CO92 autoinducer-2 (AI-2) kinase YP_002345491.1 432673 D 214092 CDS YP_002345492.1 218927617 1173261 434734..435774 1 NC_003143.1 lipopolysaccharide core biosynthesis protein 435774 1173261 YPO0416 Yersinia pestis CO92 lipopolysaccharide core biosynthesis protein YP_002345492.1 434734 D 214092 CDS YP_002345493.1 218927618 1173262 435822..437054 1 NC_003143.1 O-antigen biosynthesis protein 437054 1173262 YPO0417 Yersinia pestis CO92 O-antigen biosynthesis protein YP_002345493.1 435822 D 214092 CDS YP_002345495.1 218927620 1173264 437864..438097 1 NC_003143.1 hypothetical protein 438097 1173264 YPO0419 Yersinia pestis CO92 hypothetical protein YP_002345495.1 437864 D 214092 CDS YP_002345496.1 218927621 1173265 438149..439231 1 NC_003143.1 lipoprotein 439231 1173265 YPO0420 Yersinia pestis CO92 lipoprotein YP_002345496.1 438149 D 214092 CDS YP_002345497.1 218927622 1173266 439231..442317 1 NC_003143.1 multi-drug efflux protein 442317 1173266 YPO0421 Yersinia pestis CO92 multi-drug efflux protein YP_002345497.1 439231 D 214092 CDS YP_002345498.1 218927623 1173267 complement(442678..443010) 1 NC_003143.1 No significant database hits; hypothetical protein 443010 1173267 YPO0422 Yersinia pestis CO92 hypothetical protein YP_002345498.1 442678 R 214092 CDS YP_002345500.1 218927625 1173269 443813..444898 1 NC_003143.1 pectinesterase 444898 1173269 YPO0424 Yersinia pestis CO92 pectinesterase YP_002345500.1 443813 D 214092 CDS YP_002345501.1 218927626 1173270 complement(445439..446611) 1 NC_003143.1 HmsT protein 446611 hmsT 1173270 hmsT Yersinia pestis CO92 HmsT protein YP_002345501.1 445439 R 214092 CDS YP_002345502.2 537470132 1173271 446860..447192 1 NC_003143.1 hypothetical protein 447192 1173271 YPO0426 Yersinia pestis CO92 hypothetical protein YP_002345502.2 446860 D 214092 CDS YP_002345503.1 218927628 1173273 complement(447705..448748) 1 NC_003143.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 448748 rsmC 1173273 rsmC Yersinia pestis CO92 16S ribosomal RNA m2G1207 methyltransferase YP_002345503.1 447705 R 214092 CDS YP_002345504.1 218927629 1173274 448861..449298 1 NC_003143.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 449298 holD 1173274 holD Yersinia pestis CO92 DNA polymerase III subunit psi YP_002345504.1 448861 D 214092 CDS YP_002345505.1 218927630 1173275 449243..449686 1 NC_003143.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 449686 rimI 1173275 rimI Yersinia pestis CO92 ribosomal-protein-alanine N-acetyltransferase YP_002345505.1 449243 D 214092 CDS YP_002345506.1 218927631 1173276 449865..451454 1 NC_003143.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 451454 prfC 1173276 prfC Yersinia pestis CO92 peptide chain release factor 3 YP_002345506.1 449865 D 214092 CDS YP_002345507.1 218927632 1173277 451781..452395 1 NC_003143.1 hypothetical protein 452395 osmY 1173277 osmY Yersinia pestis CO92 hypothetical protein YP_002345507.1 451781 D 214092 CDS YP_002345508.1 218927633 1173278 452562..452723 1 NC_003143.1 hypothetical protein 452723 1173278 YPO0432 Yersinia pestis CO92 hypothetical protein YP_002345508.1 452562 D 214092 CDS YP_002345509.1 218927634 1173279 452797..454068 1 NC_003143.1 hypothetical protein 454068 1173279 YPO0433 Yersinia pestis CO92 hypothetical protein YP_002345509.1 452797 D 214092 CDS YP_002345510.1 218927635 1173280 454105..454893 1 NC_003143.1 metalloenzyme 454893 1173280 YPO0434 Yersinia pestis CO92 metalloenzyme YP_002345510.1 454105 D 214092 CDS YP_002345511.1 218927636 1173281 455428..456699 1 NC_003143.1 Na+ dependent nucleoside transporter family protein 456699 1173281 YPO0435 Yersinia pestis CO92 Na+ dependent nucleoside transporter family protein YP_002345511.1 455428 D 214092 CDS YP_002345512.1 218927637 1173282 457275..458072 1 NC_003143.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 458072 deoC 1173282 deoC Yersinia pestis CO92 deoxyribose-phosphate aldolase YP_002345512.1 457275 D 214092 CDS YP_002345513.1 218927638 1173284 459643..460866 1 NC_003143.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 460866 deoB 1173284 deoB Yersinia pestis CO92 phosphopentomutase YP_002345513.1 459643 D 214092 CDS YP_002345514.1 218927639 1173285 460991..461710 1 NC_003143.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 461710 deoD 1173285 deoD Yersinia pestis CO92 purine nucleoside phosphorylase YP_002345514.1 460991 D 214092 CDS YP_002345515.1 218927640 1173286 complement(461822..462523) 1 NC_003143.1 hypothetical protein 462523 smp 1173286 smp Yersinia pestis CO92 hypothetical protein YP_002345515.1 461822 R 214092 CDS YP_002345516.1 218927641 1173287 462755..463735 1 NC_003143.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 463735 serB 1173287 serB Yersinia pestis CO92 phosphoserine phosphatase YP_002345516.1 462755 D 214092 CDS YP_002345517.1 218927642 1173288 463823..465205 1 NC_003143.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 465205 radA 1173288 radA Yersinia pestis CO92 DNA repair protein RadA YP_002345517.1 463823 D 214092 CDS YP_002345518.1 218927643 1173289 465364..466635 1 NC_003143.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 466635 nadR 1173289 nadR Yersinia pestis CO92 nicotinamide-nucleotide adenylyltransferase YP_002345518.1 465364 D 214092 CDS YP_002345519.1 218927644 1173290 466792..467922 1 NC_003143.1 hypothetical protein 467922 1173290 YPO0445 Yersinia pestis CO92 hypothetical protein YP_002345519.1 466792 D 214092 CDS YP_002345520.1 218927645 1173292 complement(469914..470420) 1 NC_003143.1 lipoprotein 470420 1173292 YPO0448 Yersinia pestis CO92 lipoprotein YP_002345520.1 469914 R 214092 CDS YP_002345521.1 218927646 1173293 complement(470426..471703) 1 NC_003143.1 hypothetical protein 471703 1173293 YPO0449 Yersinia pestis CO92 hypothetical protein YP_002345521.1 470426 R 214092 CDS YP_002345522.1 218927647 1173294 complement(471724..472347) 1 NC_003143.1 hypothetical protein 472347 1173294 YPO0450 Yersinia pestis CO92 hypothetical protein YP_002345522.1 471724 R 214092 CDS YP_002345523.1 218927648 1173295 complement(472722..475448) 1 NC_003143.1 cation-transporting P-type ATPase 475448 1173295 YPO0451 Yersinia pestis CO92 cation-transporting P-type ATPase YP_002345523.1 472722 R 214092 CDS YP_002345524.1 218927649 1173296 476018..477937 1 NC_003143.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 477937 slt 1173296 slt Yersinia pestis CO92 lytic murein transglycosylase YP_002345524.1 476018 D 214092 CDS YP_002345525.1 218927650 1173297 478188..478565 1 NC_003143.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 478565 trpR 1173297 trpR Yersinia pestis CO92 Trp operon repressor YP_002345525.1 478188 D 214092 CDS YP_002345526.1 218927651 1173298 complement(478562..479104) 1 NC_003143.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 479104 1173298 YPO0454 Yersinia pestis CO92 NTPase YP_002345526.1 478562 R 214092 CDS YP_002345527.1 218927652 1173299 479198..479845 1 NC_003143.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 479845 gpmB 1173299 gpmB Yersinia pestis CO92 phosphoglycerate mutase YP_002345527.1 479198 D 214092 CDS YP_002345528.1 218927653 1173300 complement(479842..480708) 1 NC_003143.1 right origin-binding protein 480708 rob 1173300 rob Yersinia pestis CO92 right origin-binding protein YP_002345528.1 479842 R 214092 CDS YP_002345529.1 218927654 1173301 480934..481401 1 NC_003143.1 hypothetical protein 481401 creA 1173301 creA Yersinia pestis CO92 hypothetical protein YP_002345529.1 480934 D 214092 CDS YP_002345530.1 218927655 1173302 complement(481575..482291) 1 NC_003143.1 two-component response regulator 482291 arcA 1173302 arcA Yersinia pestis CO92 two-component response regulator YP_002345530.1 481575 R 214092 CDS YP_002345531.1 218927656 1173303 483395..485854 1 NC_003143.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 485854 thrA 1173303 thrA Yersinia pestis CO92 bifunctional aspartokinase I/homoserine dehydrogenase I YP_002345531.1 483395 D 214092 CDS YP_002345532.1 218927657 1173304 485857..486786 1 NC_003143.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 486786 thrB 1173304 thrB Yersinia pestis CO92 homoserine kinase YP_002345532.1 485857 D 214092 CDS YP_002345533.1 218927658 1173305 486790..488079 1 NC_003143.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 488079 thrC 1173305 thrC Yersinia pestis CO92 threonine synthase YP_002345533.1 486790 D 214092 CDS YP_002345534.1 218927659 1173306 complement(488896..489672) 1 NC_003143.1 hypothetical protein 489672 1173306 YPO0462 Yersinia pestis CO92 hypothetical protein YP_002345534.1 488896 R 214092 CDS YP_002345535.1 218927660 1173307 490204..491157 1 NC_003143.1 transaldolase B 491157 talB 1173307 talB Yersinia pestis CO92 transaldolase B YP_002345535.1 490204 D 214092 CDS YP_002345536.1 218927661 1173308 491445..492032 1 NC_003143.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 492032 mogA 1173308 mogA Yersinia pestis CO92 molybdenum cofactor biosynthesis protein MogA YP_002345536.1 491445 D 214092 CDS YP_002345537.1 218927662 1173309 492160..493548 1 NC_003143.1 transport protein 493548 1173309 YPO0465 Yersinia pestis CO92 transport protein YP_002345537.1 492160 D 214092 CDS YP_002345538.1 218927663 1173310 complement(493618..496065) 1 NC_003143.1 No significant database matches. CDS DNA contains low GC content, 35.33%; hypothetical protein 496065 1173310 YPO0466 Yersinia pestis CO92 hypothetical protein YP_002345538.1 493618 R 214092 CDS YP_002345539.1 218927664 1173311 complement(496354..496965) 1 NC_003143.1 hypothetical protein 496965 yaaH 1173311 yaaH Yersinia pestis CO92 hypothetical protein YP_002345539.1 496354 R 214092 CDS YP_002345540.1 218927665 1173312 497339..499249 1 NC_003143.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 499249 dnaK 1173312 dnaK Yersinia pestis CO92 molecular chaperone DnaK YP_002345540.1 497339 D 214092 CDS YP_002345541.1 218927666 1173313 499361..500500 1 NC_003143.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 500500 dnaJ 1173313 dnaJ Yersinia pestis CO92 molecular chaperone DnaJ YP_002345541.1 499361 D 214092 CDS YP_002345542.1 218927667 1173314 500743..501927 1 NC_003143.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 501927 nhaA 1173314 nhaA Yersinia pestis CO92 pH-dependent sodium/proton antiporter YP_002345542.1 500743 D 214092 CDS YP_002345543.1 218927668 1173315 502057..502956 1 NC_003143.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 502956 nhaR 1173315 nhaR Yersinia pestis CO92 transcriptional activator NhaR YP_002345543.1 502057 D 214092 CDS YP_002345544.1 218927669 1173316 complement(503087..503350) 1 NC_003143.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 503350 rpsT 1173316 rpsT Yersinia pestis CO92 30S ribosomal protein S20 YP_002345544.1 503087 R 214092 CDS YP_002345546.1 218927671 1173318 503765..504703 1 NC_003143.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 504703 ribF 1173318 ribF Yersinia pestis CO92 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002345546.1 503765 D 214092 CDS YP_002345547.1 218927672 1173319 504735..507551 1 NC_003143.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 507551 ileS 1173319 ileS Yersinia pestis CO92 isoleucyl-tRNA synthetase YP_002345547.1 504735 D 214092 CDS YP_002345548.1 218927673 1173320 507551..508060 1 NC_003143.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 508060 lspA 1173320 lspA Yersinia pestis CO92 lipoprotein signal peptidase YP_002345548.1 507551 D 214092 CDS YP_002345549.1 218927674 1173321 508128..508586 1 NC_003143.1 FKBP-type peptidylprolyl isomerase 508586 1173321 YPO0476a Yersinia pestis CO92 FKBP-type peptidylprolyl isomerase YP_002345549.1 508128 D 214092 CDS YP_002345550.1 218927675 1173322 508567..509520 1 NC_003143.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 509520 ispH 1173322 ispH Yersinia pestis CO92 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_002345550.1 508567 D 214092 CDS YP_002345552.1 218927677 1173324 509902..510360 1 NC_003143.1 transposase for the IS1541 insertion element 510360 tnp 1173324 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345552.1 509902 D 214092 CDS YP_002345553.1 218927678 1173325 510813..511634 1 NC_003143.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 511634 dapB 1173325 dapB Yersinia pestis CO92 dihydrodipicolinate reductase YP_002345553.1 510813 D 214092 CDS YP_002345554.1 218927679 1173326 512107..513282 1 NC_003143.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 513282 carA 1173326 carA Yersinia pestis CO92 carbamoyl phosphate synthase small subunit YP_002345554.1 512107 D 214092 CDS YP_002345555.1 218927680 1173327 513298..516531 1 NC_003143.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 516531 carB 1173327 carB Yersinia pestis CO92 carbamoyl phosphate synthase large subunit YP_002345555.1 513298 D 214092 CDS YP_002345556.1 218927681 1173328 complement(516759..517373) 1 NC_003143.1 LysE type translocator 517373 1173328 YPO0483 Yersinia pestis CO92 LysE type translocator YP_002345556.1 516759 R 214092 CDS YP_002345557.1 218927682 1173329 517697..518497 1 NC_003143.1 hypothetical protein 518497 1173329 YPO0484 Yersinia pestis CO92 hypothetical protein YP_002345557.1 517697 D 214092 CDS YP_002345558.2 229220641 1173330 518488..518949 1 NC_003143.1 hypothetical protein 518949 1173330 YPO0485 Yersinia pestis CO92 hypothetical protein YP_002345558.2 518488 D 214092 CDS YP_002345559.1 218927684 1173331 519099..519581 1 NC_003143.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 519581 folA 1173331 folA Yersinia pestis CO92 dihydrofolate reductase YP_002345559.1 519099 D 214092 CDS YP_002345560.1 218927685 1173332 519793..520251 1 NC_003143.1 transposase for the IS1541 insertion element 520251 tnp 1173332 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345560.1 519793 D 214092 CDS YP_008479680.1 537470133 16744737 complement(520355..520519) 1 NC_003143.1 hypothetical protein 520519 16744737 YPO0489a Yersinia pestis CO92 hypothetical protein YP_008479680.1 520355 R 214092 CDS YP_002345562.1 218927687 1173334 521134..521598 1 NC_003143.1 hypothetical protein 521598 1173334 YPO0489 Yersinia pestis CO92 hypothetical protein YP_002345562.1 521134 D 214092 CDS YP_002345563.1 218927688 1173335 complement(521688..522557) 1 NC_003143.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 522557 apaH 1173335 apaH Yersinia pestis CO92 diadenosine tetraphosphatase YP_002345563.1 521688 R 214092 CDS YP_002345564.1 218927689 1173336 complement(522574..522951) 1 NC_003143.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 522951 apaG 1173336 apaG Yersinia pestis CO92 ApaG protein YP_002345564.1 522574 R 214092 CDS YP_002345565.1 218927690 1173337 complement(522965..523783) 1 NC_003143.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 523783 ksgA 1173337 ksgA Yersinia pestis CO92 dimethyladenosine transferase YP_002345565.1 522965 R 214092 CDS YP_002345566.1 218927691 1173338 complement(523776..524771) 1 NC_003143.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 524771 pdxA 1173338 pdxA Yersinia pestis CO92 4-hydroxythreonine-4-phosphate dehydrogenase YP_002345566.1 523776 R 214092 CDS YP_002345567.1 218927692 1173339 complement(524755..526059) 1 NC_003143.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 526059 surA 1173339 surA Yersinia pestis CO92 peptidyl-prolyl cis-trans isomerase SurA YP_002345567.1 524755 R 214092 CDS YP_002345568.1 218927693 1173340 complement(526127..528469) 1 NC_003143.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 528469 imp 1173340 imp Yersinia pestis CO92 organic solvent tolerance protein YP_002345568.1 526127 R 214092 CDS YP_002345569.1 218927694 1173341 528654..529487 1 NC_003143.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 529487 djlA 1173341 djlA Yersinia pestis CO92 Dna-J like membrane chaperone protein YP_002345569.1 528654 D 214092 CDS YP_002345570.1 218927695 1173342 complement(529785..530405) 1 NC_003143.1 ribosomal large subunit pseudouridine synthase A 530405 rluA 1173342 rluA Yersinia pestis CO92 ribosomal large subunit pseudouridine synthase A YP_002345570.1 529785 R 214092 CDS YP_002345571.1 218927696 1173343 complement(531628..532371) 1 NC_003143.1 No significant database hits; hypothetical protein 532371 1173343 YPO0498 Yersinia pestis CO92 hypothetical protein YP_002345571.1 531628 R 214092 CDS YP_002345572.1 218927697 1173344 532701..533714 1 NC_003143.1 hypothetical protein 533714 1173344 YPO0499 Yersinia pestis CO92 hypothetical protein YP_002345572.1 532701 D 214092 CDS YP_002345573.1 218927698 1173345 533725..534285 1 NC_003143.1 hypothetical protein 534285 1173345 YPO0500 Yersinia pestis CO92 hypothetical protein YP_002345573.1 533725 D 214092 CDS YP_002345574.1 218927699 1173346 534285..535796 1 NC_003143.1 hypothetical protein 535796 1173346 YPO0501 Yersinia pestis CO92 hypothetical protein YP_002345574.1 534285 D 214092 CDS YP_002345575.1 218927700 1173347 535959..536477 1 NC_003143.1 hypothetical protein 536477 1173347 YPO0502 Yersinia pestis CO92 hypothetical protein YP_002345575.1 535959 D 214092 CDS YP_002345576.1 218927701 1173348 536551..536994 1 NC_003143.1 hypothetical protein 536994 1173348 YPO0503 Yersinia pestis CO92 hypothetical protein YP_002345576.1 536551 D 214092 CDS YP_002345577.1 218927702 1173349 537027..538871 1 NC_003143.1 hypothetical protein 538871 1173349 YPO0504 Yersinia pestis CO92 hypothetical protein YP_002345577.1 537027 D 214092 CDS YP_002345578.1 218927703 1173350 538864..539847 1 NC_003143.1 hypothetical protein 539847 1173350 YPO0505 Yersinia pestis CO92 hypothetical protein YP_002345578.1 538864 D 214092 CDS YP_002345579.1 218927704 1173351 539850..542453 1 NC_003143.1 Clp ATPase 542453 clpB 1173351 clpB Yersinia pestis CO92 Clp ATPase YP_002345579.1 539850 D 214092 CDS YP_002345580.1 218927705 1173352 542557..544905 1 NC_003143.1 hypothetical protein 544905 1173352 YPO0507 Yersinia pestis CO92 hypothetical protein YP_002345580.1 542557 D 214092 CDS YP_002345583.1 218927708 1173355 547163..548266 1 NC_003143.1 hypothetical protein 548266 1173355 YPO0510 Yersinia pestis CO92 hypothetical protein YP_002345583.1 547163 D 214092 CDS YP_002345584.1 218927709 1173356 548259..548876 1 NC_003143.1 No significant database hits; hypothetical protein 548876 1173356 YPO0511 Yersinia pestis CO92 hypothetical protein YP_002345584.1 548259 D 214092 CDS YP_002345585.1 218927710 1173357 548882..549247 1 NC_003143.1 hypothetical protein 549247 1173357 YPO0511a Yersinia pestis CO92 hypothetical protein YP_002345585.1 548882 D 214092 CDS YP_002345586.1 218927711 1173358 549240..549731 1 NC_003143.1 lipoprotein 549731 1173358 YPO0512 Yersinia pestis CO92 lipoprotein YP_002345586.1 549240 D 214092 CDS YP_002345587.1 218927712 1173359 549851..551206 1 NC_003143.1 hypothetical protein 551206 1173359 YPO0513 Yersinia pestis CO92 hypothetical protein YP_002345587.1 549851 D 214092 CDS YP_002345588.1 218927713 1173360 551203..552813 1 NC_003143.1 hypothetical protein 552813 1173360 YPO0514 Yersinia pestis CO92 hypothetical protein YP_002345588.1 551203 D 214092 CDS YP_002345589.1 218927714 1173361 552863..556315 1 NC_003143.1 hypothetical protein 556315 1173361 YPO0515 Yersinia pestis CO92 hypothetical protein YP_002345589.1 552863 D 214092 CDS YP_002345590.1 218927715 1173362 556337..556690 1 NC_003143.1 No significant database hits; hypothetical protein 556690 1173362 YPO0516 Yersinia pestis CO92 hypothetical protein YP_002345590.1 556337 D 214092 CDS YP_002345591.1 218927716 1173363 complement(556946..559852) 1 NC_003143.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 559852 hepA 1173363 hepA Yersinia pestis CO92 ATP-dependent helicase HepA YP_002345591.1 556946 R 214092 CDS YP_002345592.1 218927717 1173364 complement(560313..562682) 1 NC_003143.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 562682 dinA 1173364 dinA Yersinia pestis CO92 DNA polymerase II YP_002345592.1 560313 R 214092 CDS YP_002345593.1 218927718 1173365 562878..563645 1 NC_003143.1 DedA family membrane protein 563645 1173365 YPO0519 Yersinia pestis CO92 DedA family membrane protein YP_002345593.1 562878 D 214092 CDS YP_002345594.1 218927719 1173366 complement(563714..564397) 1 NC_003143.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding protein 564397 thiQ 1173366 thiQ Yersinia pestis CO92 thiamine transporter ATP-binding protein YP_002345594.1 563714 R 214092 CDS YP_002345595.1 218927720 1173367 complement(564411..565970) 1 NC_003143.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 565970 thiP 1173367 thiP Yersinia pestis CO92 thiamine transporter membrane protein YP_002345595.1 564411 R 214092 CDS YP_002345596.1 218927721 1173368 complement(565994..566986) 1 NC_003143.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 566986 tbpA 1173368 tbpA Yersinia pestis CO92 thiamine transporter substrate binding subunit YP_002345596.1 565994 R 214092 CDS YP_002345597.1 218927722 1173369 567541..567825 1 NC_003143.1 hypothetical protein 567825 1173369 YPO0523 Yersinia pestis CO92 hypothetical protein YP_002345597.1 567541 D 214092 CDS YP_002345598.1 218927723 1173370 complement(567926..569587) 1 NC_003143.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 569587 1173370 YPO0524 Yersinia pestis CO92 transcriptional regulator SgrR YP_002345598.1 567926 R 214092 CDS YP_002345600.1 218927725 1173373 complement(571251..572033) 1 NC_003143.1 transposase/IS protein 572033 1173373 YPO0527 Yersinia pestis CO92 transposase/IS protein YP_002345600.1 571251 R 214092 CDS YP_002345601.1 218927726 1173374 complement(572030..573052) 1 NC_003143.1 transposase for insertion sequence IS100 573052 y1093 1173374 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002345601.1 572030 R 214092 CDS YP_002345602.1 218927727 1173375 complement(573632..574234) 1 NC_003143.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 574234 leuD 1173375 leuD Yersinia pestis CO92 isopropylmalate isomerase small subunit YP_002345602.1 573632 R 214092 CDS YP_002345603.1 218927728 1173376 complement(574249..575679) 1 NC_003143.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 575679 leuC 1173376 leuC Yersinia pestis CO92 isopropylmalate isomerase large subunit YP_002345603.1 574249 R 214092 CDS YP_002345604.1 218927729 1173377 complement(575681..576772) 1 NC_003143.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 576772 leuB 1173377 leuB Yersinia pestis CO92 3-isopropylmalate dehydrogenase YP_002345604.1 575681 R 214092 CDS YP_002345605.1 218927730 1173378 complement(576775..578337) 1 NC_003143.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 578337 leuA 1173378 leuA Yersinia pestis CO92 2-isopropylmalate synthase YP_002345605.1 576775 R 214092 CDS YP_002345606.1 218927731 1173379 complement(578484..578942) 1 NC_003143.1 transposase for the IS1541 insertion element 578942 tnp 1173379 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345606.1 578484 R 214092 CDS YP_002345607.1 218927732 1173380 580264..581220 1 NC_003143.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 581220 leuO 1173380 leuO Yersinia pestis CO92 leucine transcriptional activator YP_002345607.1 580264 D 214092 CDS YP_002345608.1 218927733 1173381 581549..581755 1 NC_003143.1 Doubtful CDS with no significant database hits; hypothetical protein 581755 1173381 YPO0536 Yersinia pestis CO92 hypothetical protein YP_002345608.1 581549 D 214092 CDS YP_002345609.1 218927734 1173382 581752..583557 1 NC_003143.1 AMP-binding protein 583557 1173382 YPO0537 Yersinia pestis CO92 AMP-binding protein YP_002345609.1 581752 D 214092 CDS YP_002345610.1 218927735 1173383 583588..583698 1 NC_003143.1 Doubtful CDS with no significant database hits; hypothetical protein 583698 1173383 YPO0538 Yersinia pestis CO92 hypothetical protein YP_002345610.1 583588 D 214092 CDS YP_002345611.1 218927736 1173384 584017..585744 1 NC_003143.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 585744 ilvI 1173384 ilvI Yersinia pestis CO92 acetolactate synthase 3 catalytic subunit YP_002345611.1 584017 D 214092 CDS YP_002345612.1 218927737 1173385 585747..586241 1 NC_003143.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 586241 ilvH 1173385 ilvH Yersinia pestis CO92 acetolactate synthase 3 regulatory subunit YP_002345612.1 585747 D 214092 CDS YP_002345613.1 218927738 1173386 586440..586898 1 NC_003143.1 transposase for the IS1541 insertion element 586898 tnp 1173386 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345613.1 586440 D 214092 CDS YP_002345614.1 218927739 1173387 complement(587220..587336) 1 NC_003143.1 Doubtful CDS with no significant database hits; hypothetical protein 587336 1173387 YPO0542 Yersinia pestis CO92 hypothetical protein YP_002345614.1 587220 R 214092 CDS YP_002345615.1 218927740 1173388 587403..588413 1 NC_003143.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 588413 fruR 1173388 fruR Yersinia pestis CO92 DNA-binding transcriptional regulator FruR YP_002345615.1 587403 D 214092 CDS YP_002345616.1 218927741 1173389 complement(588544..588990) 1 NC_003143.1 hypothetical protein 588990 1173389 YPO0544 Yersinia pestis CO92 hypothetical protein YP_002345616.1 588544 R 214092 CDS YP_002345617.1 218927742 1173390 590086..590544 1 NC_003143.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 590544 1173390 YPO0546 Yersinia pestis CO92 cell division protein MraZ YP_002345617.1 590086 D 214092 CDS YP_002345618.1 218927743 1173391 590547..591509 1 NC_003143.1 S-adenosyl-methyltransferase MraW 591509 mraW 1173391 mraW Yersinia pestis CO92 S-adenosyl-methyltransferase MraW YP_002345618.1 590547 D 214092 CDS YP_002345619.1 218927744 1173392 591506..591823 1 NC_003143.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 591823 ftsL 1173392 ftsL Yersinia pestis CO92 cell division protein FtsL YP_002345619.1 591506 D 214092 CDS YP_002345620.1 218927745 1173393 591889..593652 1 NC_003143.1 penicillin-binding protein 3 593652 ftsI 1173393 ftsI Yersinia pestis CO92 penicillin-binding protein 3 YP_002345620.1 591889 D 214092 CDS YP_002345621.1 218927746 1173394 593654..595126 1 NC_003143.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 595126 murE 1173394 murE Yersinia pestis CO92 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_002345621.1 593654 D 214092 CDS YP_002345622.1 218927747 1173395 595123..596499 1 NC_003143.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 596499 murF 1173395 murF Yersinia pestis CO92 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_002345622.1 595123 D 214092 CDS YP_002345623.1 218927748 1173396 596493..597575 1 NC_003143.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 597575 mraY 1173396 mraY Yersinia pestis CO92 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002345623.1 596493 D 214092 CDS YP_002345624.1 218927749 1173397 597578..598894 1 NC_003143.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 598894 murD 1173397 murD Yersinia pestis CO92 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002345624.1 597578 D 214092 CDS YP_002345625.1 218927750 1173398 598894..600096 1 NC_003143.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 600096 ftsW 1173398 ftsW Yersinia pestis CO92 cell division protein FtsW YP_002345625.1 598894 D 214092 CDS YP_002345626.1 218927751 1173399 600093..601163 1 NC_003143.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 601163 murG 1173399 murG Yersinia pestis CO92 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_002345626.1 600093 D 214092 CDS YP_002345627.1 218927752 1173400 601301..602776 1 NC_003143.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 602776 murC 1173400 murC Yersinia pestis CO92 UDP-N-acetylmuramate--L-alanine ligase YP_002345627.1 601301 D 214092 CDS YP_002345628.1 218927753 1173401 602769..603689 1 NC_003143.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 603689 ddl 1173401 ddl Yersinia pestis CO92 D-alanine--D-alanine ligase YP_002345628.1 602769 D 214092 CDS YP_002345629.1 218927754 1173402 603691..604518 1 NC_003143.1 involved in septum formation; cell division protein FtsQ 604518 ftsQ 1173402 ftsQ Yersinia pestis CO92 cell division protein FtsQ YP_002345629.1 603691 D 214092 CDS YP_002345630.1 218927755 1173403 604545..605801 1 NC_003143.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 605801 ftsA 1173403 ftsA Yersinia pestis CO92 cell division protein FtsA YP_002345630.1 604545 D 214092 CDS YP_002345631.1 218927756 1173404 605874..607025 1 NC_003143.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 607025 ftsZ 1173404 ftsZ Yersinia pestis CO92 cell division protein FtsZ YP_002345631.1 605874 D 214092 CDS YP_002345632.1 218927757 1173405 607125..608045 1 NC_003143.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 608045 lpxC 1173405 lpxC Yersinia pestis CO92 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_002345632.1 607125 D 214092 CDS YP_002345633.1 218927758 1173406 complement(608212..608742) 1 NC_003143.1 hypothetical protein 608742 1173406 YPO0562 Yersinia pestis CO92 hypothetical protein YP_002345633.1 608212 R 214092 CDS YP_002345634.1 218927759 1173407 608765..609298 1 NC_003143.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 609298 1173407 YPO0563 Yersinia pestis CO92 SecA regulator SecM YP_002345634.1 608765 D 214092 CDS YP_002345635.1 218927760 1173408 609376..612090 1 NC_003143.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 612090 secA 1173408 secA Yersinia pestis CO92 preprotein translocase subunit SecA YP_002345635.1 609376 D 214092 CDS YP_002345636.1 218927761 1173409 612385..612771 1 NC_003143.1 nucleoside triphosphate pyrophosphohydrolase 612771 mutT 1173409 mutT Yersinia pestis CO92 nucleoside triphosphate pyrophosphohydrolase YP_002345636.1 612385 D 214092 CDS YP_002345637.1 218927762 1173410 complement(613033..613815) 1 NC_003143.1 transposase/IS protein 613815 1173410 YPO0566 Yersinia pestis CO92 transposase/IS protein YP_002345637.1 613033 R 214092 CDS YP_002345638.1 218927763 1173411 complement(613812..614834) 1 NC_003143.1 transposase for insertion sequence IS100 614834 y1093 1173411 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002345638.1 613812 R 214092 CDS YP_002345639.1 218927764 1173412 complement(615113..615481) 1 NC_003143.1 hypothetical protein 615481 1173412 YPO0568 Yersinia pestis CO92 hypothetical protein YP_002345639.1 615113 R 214092 CDS YP_002345640.1 218927765 1173413 complement(615812..616096) 1 NC_003143.1 hypothetical protein 616096 1173413 YPO0569 Yersinia pestis CO92 hypothetical protein YP_002345640.1 615812 R 214092 CDS YP_002345641.1 218927766 1173414 complement(616093..616488) 1 NC_003143.1 hypothetical protein 616488 1173414 YPO0569a Yersinia pestis CO92 hypothetical protein YP_002345641.1 616093 R 214092 CDS YP_002345642.1 218927767 1173415 complement(616491..616796) 1 NC_003143.1 hypothetical protein 616796 yqjD 1173415 yqjD Yersinia pestis CO92 hypothetical protein YP_002345642.1 616491 R 214092 CDS YP_002345643.1 218927768 1173416 complement(616801..616947) 1 NC_003143.1 No significant database hits; hypothetical protein 616947 1173416 YPO0571 Yersinia pestis CO92 hypothetical protein YP_002345643.1 616801 R 214092 CDS YP_002345644.1 218927769 1173417 complement(616951..617331) 1 NC_003143.1 hypothetical protein 617331 1173417 YPO0572 Yersinia pestis CO92 hypothetical protein YP_002345644.1 616951 R 214092 CDS YP_002345645.1 218927770 1173418 complement(617557..617946) 1 NC_003143.1 hypothetical protein 617946 1173418 YPO0573 Yersinia pestis CO92 hypothetical protein YP_002345645.1 617557 R 214092 CDS YP_002345646.1 218927771 1173419 complement(617943..618641) 1 NC_003143.1 DedA family membrane protein 618641 yqjA 1173419 yqjA Yersinia pestis CO92 DedA family membrane protein YP_002345646.1 617943 R 214092 CDS YP_002345647.1 218927772 1173420 complement(618919..619473) 1 NC_003143.1 Doubtful CDS. No significant database matches; lipoprotein 619473 1173420 YPO0575 Yersinia pestis CO92 lipoprotein YP_002345647.1 618919 R 214092 CDS YP_002345648.1 218927773 1173421 complement(619701..620495) 1 NC_003143.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 620495 exuR 1173421 exuR Yersinia pestis CO92 DNA-binding transcriptional repressor ExuR YP_002345648.1 619701 R 214092 CDS YP_002345649.1 218927774 1173422 complement(620758..622062) 1 NC_003143.1 ExuT transport protein 622062 exuT 1173422 exuT Yersinia pestis CO92 ExuT transport protein YP_002345649.1 620758 R 214092 CDS YP_002345651.1 218927776 1173424 622807..624216 1 NC_003143.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 624216 uxaC 1173424 uxaC Yersinia pestis CO92 glucuronate isomerase YP_002345651.1 622807 D 214092 CDS YP_002345652.1 218927777 1173425 624415..625866 1 NC_003143.1 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 625866 uxaB 1173425 uxaB Yersinia pestis CO92 altronate oxidoreductase YP_002345652.1 624415 D 214092 CDS YP_002345653.1 218927778 1173426 625877..627367 1 NC_003143.1 altronate hydrolase 627367 uxaA 1173426 uxaA Yersinia pestis CO92 altronate hydrolase YP_002345653.1 625877 D 214092 CDS YP_002345654.1 218927779 1173427 627520..628050 1 NC_003143.1 hypothetical protein 628050 1173427 YPO0582 Yersinia pestis CO92 hypothetical protein YP_002345654.1 627520 D 214092 CDS YP_002345655.1 218927780 1173428 complement(628168..628626) 1 NC_003143.1 transposase for the IS1541 insertion element 628626 tnp 1173428 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345655.1 628168 R 214092 CDS YP_002345656.1 218927781 1173429 complement(628827..630095) 1 NC_003143.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 630095 1173429 YPO0584 Yersinia pestis CO92 serine/threonine transporter SstT YP_002345656.1 628827 R 214092 CDS YP_002345657.1 218927782 1173430 complement(630618..631613) 1 NC_003143.1 MocA family oxidoreductase 631613 1173430 YPO0585 Yersinia pestis CO92 MocA family oxidoreductase YP_002345657.1 630618 R 214092 CDS YP_002345658.1 218927783 1173431 complement(631816..632325) 1 NC_003143.1 hypothetical protein 632325 1173431 YPO0586 Yersinia pestis CO92 hypothetical protein YP_002345658.1 631816 R 214092 CDS YP_002345659.1 218927784 1173432 complement(632564..635548) 1 NC_003143.1 autotransporter protein 635548 1173432 YPO0587 Yersinia pestis CO92 autotransporter protein YP_002345659.1 632564 R 214092 CDS YP_002345660.1 218927785 1173433 636017..637204 1 NC_003143.1 methyltransferase 637204 1173433 YPO0588 Yersinia pestis CO92 methyltransferase YP_002345660.1 636017 D 214092 CDS YP_002345661.1 218927786 1173434 complement(637320..639341) 1 NC_003143.1 2,4-dienoyl-CoA reductase 639341 fadH 1173434 fadH Yersinia pestis CO92 2,4-dienoyl-CoA reductase YP_002345661.1 637320 R 214092 CDS YP_002345662.1 218927787 1173435 complement(639554..640123) 1 NC_003143.1 acid-resistance membrane protein 640123 hdeD 1173435 hdeD Yersinia pestis CO92 acid-resistance membrane protein YP_002345662.1 639554 R 214092 CDS YP_002345664.1 218927789 1173437 complement(640514..642013) 1 NC_003143.1 kinase protein 642013 1173437 YPO0592 Yersinia pestis CO92 kinase protein YP_002345664.1 640514 R 214092 CDS YP_002345665.1 218927790 1173438 complement(642045..643778) 1 NC_003143.1 hypothetical protein 643778 1173438 YPO0593 Yersinia pestis CO92 hypothetical protein YP_002345665.1 642045 R 214092 CDS YP_002345666.1 218927791 1173439 complement(643834..644817) 1 NC_003143.1 hypothetical protein 644817 1173439 YPO0594 Yersinia pestis CO92 hypothetical protein YP_002345666.1 643834 R 214092 CDS YP_002345667.1 218927792 1173440 complement(644919..645557) 1 NC_003143.1 hypothetical protein 645557 1173440 YPO0595 Yersinia pestis CO92 hypothetical protein YP_002345667.1 644919 R 214092 CDS YP_002345668.1 218927793 1173441 complement(645559..646200) 1 NC_003143.1 tellurium resistance protein 646200 terX 1173441 terX Yersinia pestis CO92 tellurium resistance protein YP_002345668.1 645559 R 214092 CDS YP_002345669.1 218927794 1173442 complement(646233..646871) 1 NC_003143.1 tellurium resistance protein 646871 terY 1173442 terY Yersinia pestis CO92 tellurium resistance protein YP_002345669.1 646233 R 214092 CDS YP_002345670.1 218927795 1173443 647586..649274 1 NC_003143.1 hemolysin activator protein 649274 1173443 YPO0598 Yersinia pestis CO92 hemolysin activator protein YP_002345670.1 647586 D 214092 CDS YP_002345671.1 218927796 1173444 649319..659206 1 NC_003143.1 adhesin 659206 1173444 YPO0599 Yersinia pestis CO92 adhesin YP_002345671.1 649319 D 214092 CDS YP_002345672.1 218927797 1173445 659203..659436 1 NC_003143.1 Poor database matches. Doubtful CDS; hypothetical protein 659436 1173445 YPO0600 Yersinia pestis CO92 hypothetical protein YP_002345672.1 659203 D 214092 CDS YP_002345673.1 218927798 1173446 659702..659929 1 NC_003143.1 hypothetical protein 659929 1173446 YPO0601 Yersinia pestis CO92 hypothetical protein YP_002345673.1 659702 D 214092 CDS YP_002345674.1 218927799 1173447 660010..660441 1 NC_003143.1 No significant database hits; hypothetical protein 660441 1173447 YPO0602 Yersinia pestis CO92 hypothetical protein YP_002345674.1 660010 D 214092 CDS YP_008479681.1 537470134 16744738 660474..661229 1 NC_003143.1 hemagglutinin 661229 16744738 YPO0602a Yersinia pestis CO92 hemagglutinin YP_008479681.1 660474 D 214092 CDS YP_008479682.1 537470135 16744739 661293..661457 1 NC_003143.1 hypothetical protein 661457 16744739 YPO0602b Yersinia pestis CO92 hypothetical protein YP_008479682.1 661293 D 214092 CDS YP_002345675.1 218927800 1173449 complement(661725..664010) 1 NC_003143.1 autotransporter protein 664010 yapF 1173449 yapF Yersinia pestis CO92 autotransporter protein YP_002345675.1 661725 R 214092 CDS YP_002345676.1 218927801 1173450 complement(664070..665065) 1 NC_003143.1 hypothetical protein 665065 1173450 YPO0607 Yersinia pestis CO92 hypothetical protein YP_002345676.1 664070 R 214092 CDS YP_002345677.1 218927802 1173451 complement(665167..666546) 1 NC_003143.1 hypothetical protein 666546 1173451 YPO0608 Yersinia pestis CO92 hypothetical protein YP_002345677.1 665167 R 214092 CDS YP_002345678.1 218927803 1173452 666869..667987 1 NC_003143.1 transporter ATP-binding protein 667987 1173452 YPO0609 Yersinia pestis CO92 transporter ATP-binding protein YP_002345678.1 666869 D 214092 CDS YP_002345679.1 218927804 1173453 668070..671423 1 NC_003143.1 hypothetical protein 671423 1173453 YPO0610 Yersinia pestis CO92 hypothetical protein YP_002345679.1 668070 D 214092 CDS YP_002345680.1 218927805 1173454 671532..672518 1 NC_003143.1 LacI family regulatory protein 672518 1173454 YPO0611 Yersinia pestis CO92 LacI family regulatory protein YP_002345680.1 671532 D 214092 CDS YP_002345681.1 218927806 1173455 672595..673839 1 NC_003143.1 sugar binding protein 673839 1173455 YPO0612 Yersinia pestis CO92 sugar binding protein YP_002345681.1 672595 D 214092 CDS YP_002345682.1 218927807 1173456 673893..674774 1 NC_003143.1 permease 674774 1173456 YPO0613 Yersinia pestis CO92 permease YP_002345682.1 673893 D 214092 CDS YP_002345683.1 218927808 1173457 674774..675592 1 NC_003143.1 permease 675592 1173457 YPO0614 Yersinia pestis CO92 permease YP_002345683.1 674774 D 214092 CDS YP_002345684.1 218927809 1173458 675622..676104 1 NC_003143.1 hypothetical protein 676104 1173458 YPO0615 Yersinia pestis CO92 hypothetical protein YP_002345684.1 675622 D 214092 CDS YP_002345685.1 218927810 1173459 676155..678338 1 NC_003143.1 glycosyl hydrolase 678338 1173459 YPO0616 Yersinia pestis CO92 glycosyl hydrolase YP_002345685.1 676155 D 214092 CDS YP_002345686.1 218927811 1173460 complement(678402..679928) 1 NC_003143.1 hypothetical protein 679928 1173460 YPO0617 Yersinia pestis CO92 hypothetical protein YP_002345686.1 678402 R 214092 CDS YP_002345687.1 218927812 1173461 complement(679933..681702) 1 NC_003143.1 hypothetical protein 681702 1173461 YPO0618 Yersinia pestis CO92 hypothetical protein YP_002345687.1 679933 R 214092 CDS YP_002345688.1 218927813 1173462 complement(681818..682867) 1 NC_003143.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 682867 1173462 YPO0619 Yersinia pestis CO92 multidrug resistance protein MdtN YP_002345688.1 681818 R 214092 CDS YP_002345689.1 218927814 1173463 complement(682877..683203) 1 NC_003143.1 hypothetical protein 683203 1173463 YPO0620 Yersinia pestis CO92 hypothetical protein YP_002345689.1 682877 R 214092 CDS YP_002345690.1 218927815 1173464 complement(683209..683409) 1 NC_003143.1 No significant database hits; hypothetical protein 683409 1173464 YPO0621 Yersinia pestis CO92 hypothetical protein YP_002345690.1 683209 R 214092 CDS YP_002345691.1 218927816 1173465 complement(683582..683689) 1 NC_003143.1 No significant database hits; hypothetical protein 683689 1173465 YPO0622 Yersinia pestis CO92 hypothetical protein YP_002345691.1 683582 R 214092 CDS YP_002345692.1 218927817 1173466 684175..685407 1 NC_003143.1 aminotransferase 685407 1173466 YPO0623 Yersinia pestis CO92 aminotransferase YP_002345692.1 684175 D 214092 CDS YP_002345693.1 218927818 1173467 685400..686851 1 NC_003143.1 hypothetical protein 686851 1173467 YPO0624 Yersinia pestis CO92 hypothetical protein YP_002345693.1 685400 D 214092 CDS YP_002345694.1 218927819 1173468 686855..687301 1 NC_003143.1 hypothetical protein 687301 1173468 YPO0625 Yersinia pestis CO92 hypothetical protein YP_002345694.1 686855 D 214092 CDS YP_002345695.1 218927820 1173469 687471..688061 1 NC_003143.1 hypothetical protein 688061 1173469 YPO0626 Yersinia pestis CO92 hypothetical protein YP_002345695.1 687471 D 214092 CDS YP_002345696.1 218927821 1173470 688077..688457 1 NC_003143.1 translational inhibitor protein 688457 1173470 YPO0627 Yersinia pestis CO92 translational inhibitor protein YP_002345696.1 688077 D 214092 CDS YP_002345697.1 218927822 1173471 688742..689146 1 NC_003143.1 translational inhibitor protein 689146 1173471 YPO0628 Yersinia pestis CO92 translational inhibitor protein YP_002345697.1 688742 D 214092 CDS YP_002345698.1 218927823 1173472 complement(689361..689663) 1 NC_003143.1 hypothetical protein 689663 1173472 YPO0629 Yersinia pestis CO92 hypothetical protein YP_002345698.1 689361 R 214092 CDS YP_002345699.1 218927824 1173473 complement(689923..690639) 1 NC_003143.1 hypothetical protein 690639 1173473 YPO0630 Yersinia pestis CO92 hypothetical protein YP_002345699.1 689923 R 214092 CDS YP_002345700.1 218927825 1173474 690801..691733 1 NC_003143.1 LysR family transcriptional regulator 691733 1173474 YPO0631 Yersinia pestis CO92 LysR family transcriptional regulator YP_002345700.1 690801 D 214092 CDS YP_002345701.1 218927826 1173476 complement(692692..692850) 1 NC_003143.1 doubtful CDS with no significant database hits; hypothetical protein 692850 1173476 YPO0634 Yersinia pestis CO92 hypothetical protein YP_002345701.1 692692 R 214092 CDS YP_002345703.1 218927828 1173478 693382..693636 1 NC_003143.1 doubtful CDS with no significant database hits; hypothetical protein 693636 1173478 YPO0636 Yersinia pestis CO92 hypothetical protein YP_002345703.1 693382 D 214092 CDS YP_002345704.1 218927829 1173479 693801..694823 1 NC_003143.1 transposase for insertion sequence IS100 694823 y1093 1173479 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002345704.1 693801 D 214092 CDS YP_002345705.1 218927830 1173480 694820..695602 1 NC_003143.1 transposase/IS protein 695602 1173480 YPO0638 Yersinia pestis CO92 transposase/IS protein YP_002345705.1 694820 D 214092 CDS YP_002345707.1 218927832 1173482 697119..697589 1 NC_003143.1 no significant database hits; hypothetical protein 697589 1173482 YPO0640 Yersinia pestis CO92 hypothetical protein YP_002345707.1 697119 D 214092 CDS YP_002345708.1 218927833 1173483 697667..698071 1 NC_003143.1 no significant database hits; hypothetical protein 698071 1173483 YPO0641 Yersinia pestis CO92 hypothetical protein YP_002345708.1 697667 D 214092 CDS YP_002345710.1 218927835 1173485 698575..698694 1 NC_003143.1 no significant database hits; hypothetical protein 698694 1173485 YPO0642 Yersinia pestis CO92 hypothetical protein YP_002345710.1 698575 D 214092 CDS YP_002345711.1 218927836 1173487 complement(699212..701050) 1 NC_003143.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 701050 rpoD 1173487 rpoD Yersinia pestis CO92 RNA polymerase sigma factor RpoD YP_002345711.1 699212 R 214092 CDS YP_002345712.1 218927837 1173488 complement(701208..702956) 1 NC_003143.1 synthesizes RNA primers at the replication forks; DNA primase 702956 dnaG 1173488 dnaG Yersinia pestis CO92 DNA primase YP_002345712.1 701208 R 214092 CDS YP_002345713.1 218927838 1173489 complement(703092..703307) 1 NC_003143.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 703307 rpsU 1173489 rpsU Yersinia pestis CO92 30S ribosomal protein S21 YP_002345713.1 703092 R 214092 CDS YP_002345714.1 218927839 1173490 703713..704726 1 NC_003143.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 704726 gcp 1173490 gcp Yersinia pestis CO92 DNA-binding/iron metalloprotein/AP endonuclease YP_002345714.1 703713 D 214092 CDS YP_002345715.1 218927840 1173491 complement(704972..705622) 1 NC_003143.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 705622 1173491 YPO0647 Yersinia pestis CO92 glycerol-3-phosphate acyltransferase PlsY YP_002345715.1 704972 R 214092 CDS YP_002345716.1 218927841 1173492 705730..706089 1 NC_003143.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 706089 folB 1173492 folB Yersinia pestis CO92 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_002345716.1 705730 D 214092 CDS YP_002345717.1 218927842 1173493 706363..707181 1 NC_003143.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 707181 uppP 1173493 uppP Yersinia pestis CO92 undecaprenyl pyrophosphate phosphatase YP_002345717.1 706363 D 214092 CDS YP_002345718.1 218927843 1173494 complement(707417..708655) 1 NC_003143.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 708655 cca 1173494 cca Yersinia pestis CO92 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_002345718.1 707417 R 214092 CDS YP_002345719.1 218927844 1173495 complement(708815..709438) 1 NC_003143.1 signal transduction protein 709438 1173495 YPO0651 Yersinia pestis CO92 signal transduction protein YP_002345719.1 708815 R 214092 CDS YP_002345720.1 218927845 1173496 709742..711049 1 NC_003143.1 hypothetical protein 711049 1173496 YPO0652 Yersinia pestis CO92 hypothetical protein YP_002345720.1 709742 D 214092 CDS YP_002345721.1 218927846 1173497 711220..714075 1 NC_003143.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 714075 glnE 1173497 glnE Yersinia pestis CO92 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_002345721.1 711220 D 214092 CDS YP_002345722.1 218927847 1173498 714210..715640 1 NC_003143.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 715640 rfaE 1173498 rfaE Yersinia pestis CO92 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_002345722.1 714210 D 214092 CDS YP_002345723.1 218927848 1173499 715677..716927 1 NC_003143.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; hypothetical protein 716927 asoB 1173499 asoB Yersinia pestis CO92 hypothetical protein YP_002345723.1 715677 D 214092 CDS YP_002345724.1 218927849 1173500 complement(717252..717533) 1 NC_003143.1 hypothetical protein 717533 1173500 YPO0656 Yersinia pestis CO92 hypothetical protein YP_002345724.1 717252 R 214092 CDS YP_002345726.1 218927851 1173502 718102..718755 1 NC_003143.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 718755 ribB 1173502 ribB Yersinia pestis CO92 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_002345726.1 718102 D 214092 CDS YP_002345727.1 218927852 1173503 719214..719996 1 NC_003143.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 719996 1173503 YPO0659 Yersinia pestis CO92 hypothetical protein YP_002345727.1 719214 D 214092 CDS YP_002345728.1 218927853 1173504 complement(720403..721563) 1 NC_003143.1 hypothetical protein 721563 1173504 YPO0660 Yersinia pestis CO92 hypothetical protein YP_002345728.1 720403 R 214092 CDS YP_002345729.1 218927854 1173505 complement(721573..722259) 1 NC_003143.1 hypothetical protein 722259 1173505 YPO0661 Yersinia pestis CO92 hypothetical protein YP_002345729.1 721573 R 214092 CDS YP_002345730.1 218927855 1173506 722325..722495 1 NC_003143.1 doubtful CDS with no significant database matches; hypothetical protein 722495 1173506 YPO0662 Yersinia pestis CO92 hypothetical protein YP_002345730.1 722325 D 214092 CDS YP_002345731.1 218927856 1173507 complement(722560..723957) 1 NC_003143.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 723957 tolC 1173507 tolC Yersinia pestis CO92 outer membrane channel protein YP_002345731.1 722560 R 214092 CDS YP_002345732.1 218927857 1173508 724353..724985 1 NC_003143.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase 724985 nudF 1173508 nudF Yersinia pestis CO92 ADP-ribose pyrophosphatase YP_002345732.1 724353 D 214092 CDS YP_002345733.1 218927858 1173509 725019..725444 1 NC_003143.1 hypothetical protein 725444 1173509 YPO0665 Yersinia pestis CO92 hypothetical protein YP_002345733.1 725019 D 214092 CDS YP_002345734.1 218927859 1173510 725526..726353 1 NC_003143.1 cyclic 3',5'-adenosine monophosphate phosphodiesterase 726353 icc 1173510 icc Yersinia pestis CO92 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_002345734.1 725526 D 214092 CDS YP_002345735.1 218927860 1173511 726350..726934 1 NC_003143.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase 726934 1173511 YPO0667 Yersinia pestis CO92 esterase YP_002345735.1 726350 D 214092 CDS YP_002345736.1 218927861 1173512 727036..728931 1 NC_003143.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 728931 parE 1173512 parE Yersinia pestis CO92 DNA topoisomerase IV subunit B YP_002345736.1 727036 D 214092 CDS YP_002345737.1 218927862 1173513 728935..729846 1 NC_003143.1 LysR family transcriptional regulator 729846 crgA 1173513 crgA Yersinia pestis CO92 LysR family transcriptional regulator YP_002345737.1 728935 D 214092 CDS YP_002345738.1 218927863 1173514 complement(729904..730488) 1 NC_003143.1 modulator of drug activity 730488 mda66 1173514 mda66 Yersinia pestis CO92 modulator of drug activity YP_002345738.1 729904 R 214092 CDS YP_002345739.1 218927864 1173515 730792..733065 1 NC_003143.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 733065 parC 1173515 parC Yersinia pestis CO92 DNA topoisomerase IV subunit A YP_002345739.1 730792 D 214092 CDS YP_002345740.1 218927865 1173516 733354..734085 1 NC_003143.1 acyltransferase 734085 parF 1173516 parF Yersinia pestis CO92 acyltransferase YP_002345740.1 733354 D 214092 CDS YP_002345741.1 218927866 1173517 734264..735688 1 NC_003143.1 repressor protein for FtsI 735688 sufI 1173517 sufI Yersinia pestis CO92 repressor protein for FtsI YP_002345741.1 734264 D 214092 CDS YP_002345742.1 218927867 1173519 complement(738362..739195) 1 NC_003143.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 739195 dkgA 1173519 dkgA Yersinia pestis CO92 2,5-diketo-D-gluconate reductase A YP_002345742.1 738362 R 214092 CDS YP_002345743.1 218927868 1173520 739342..739551 1 NC_003143.1 no significant database hits; hypothetical protein 739551 1173520 YPO0677 Yersinia pestis CO92 hypothetical protein YP_002345743.1 739342 D 214092 CDS YP_002345744.1 218927869 1173521 complement(739614..740771) 1 NC_003143.1 iron-containing alcohol dehydrogenase 740771 1173521 YPO0678 Yersinia pestis CO92 iron-containing alcohol dehydrogenase YP_002345744.1 739614 R 214092 CDS YP_002345745.1 218927870 1173522 741169..742062 1 NC_003143.1 AraC family transcriptional regulator 742062 1173522 YPO0679 Yersinia pestis CO92 AraC family transcriptional regulator YP_002345745.1 741169 D 214092 CDS YP_002345746.1 218927871 1173523 complement(742154..742816) 1 NC_003143.1 DedA family membrane protein 742816 1173523 YPO0680 Yersinia pestis CO92 DedA family membrane protein YP_002345746.1 742154 R 214092 CDS YP_002345747.1 218927872 1173524 complement(743009..744220) 1 NC_003143.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 744220 metC 1173524 metC Yersinia pestis CO92 cystathionine beta-lyase YP_002345747.1 743009 R 214092 CDS YP_002345748.2 537470136 1173525 744675..745736 1 NC_003143.1 MotA/TolQ/ExbB proton channel family protein 745736 1173525 YPO0682 Yersinia pestis CO92 MotA/TolQ/ExbB proton channel family protein YP_002345748.2 744675 D 214092 CDS YP_002345749.1 218927874 1173526 745740..746171 1 NC_003143.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 746171 1173526 YPO0683 Yersinia pestis CO92 biopolymer transport protein ExbD YP_002345749.1 745740 D 214092 CDS YP_002345750.1 218927875 1173527 complement(746268..747824) 1 NC_003143.1 hypothetical protein 747824 1173527 YPO0684 Yersinia pestis CO92 hypothetical protein YP_002345750.1 746268 R 214092 CDS YP_002345751.1 218927876 1173528 complement(747849..748355) 1 NC_003143.1 hypothetical protein 748355 1173528 YPO0685 Yersinia pestis CO92 hypothetical protein YP_002345751.1 747849 R 214092 CDS YP_002345752.1 218927877 1173529 complement(748405..748875) 1 NC_003143.1 hypothetical protein 748875 1173529 YPO0686 Yersinia pestis CO92 hypothetical protein YP_002345752.1 748405 R 214092 CDS YP_002345753.1 218927878 1173530 complement(748875..749609) 1 NC_003143.1 hypothetical protein 749609 1173530 YPO0687 Yersinia pestis CO92 hypothetical protein YP_002345753.1 748875 R 214092 CDS YP_002345754.1 218927879 1173531 complement(749629..750462) 1 NC_003143.1 hypothetical protein 750462 1173531 YPO0688 Yersinia pestis CO92 hypothetical protein YP_002345754.1 749629 R 214092 CDS YP_002345755.1 218927880 1173532 complement(750459..751334) 1 NC_003143.1 hypothetical protein 751334 1173532 YPO0689 Yersinia pestis CO92 hypothetical protein YP_002345755.1 750459 R 214092 CDS YP_002345756.1 218927881 1173533 complement(751331..752617) 1 NC_003143.1 type II secretion protein 752617 1173533 YPO0690 Yersinia pestis CO92 type II secretion protein YP_002345756.1 751331 R 214092 CDS YP_002345757.1 218927882 1173534 complement(752629..753861) 1 NC_003143.1 hypothetical protein 753861 1173534 YPO0691 Yersinia pestis CO92 hypothetical protein YP_002345757.1 752629 R 214092 CDS YP_002345758.1 218927883 1173536 complement(755369..756235) 1 NC_003143.1 hypothetical protein 756235 1173536 YPO0694 Yersinia pestis CO92 hypothetical protein YP_002345758.1 755369 R 214092 CDS YP_002345759.1 218927884 1173537 complement(756287..756709) 1 NC_003143.1 hypothetical protein 756709 1173537 YPO0695 Yersinia pestis CO92 hypothetical protein YP_002345759.1 756287 R 214092 CDS YP_002345760.1 218927885 1173539 756909..757367 1 NC_003143.1 transposase for the IS1541 insertion element 757367 tnp 1173539 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345760.1 756909 D 214092 CDS YP_002345761.1 218927886 1173538 757619..758077 1 NC_003143.1 transposase for the IS1541 insertion element 758077 tnp 1173538 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345761.1 757619 D 214092 CDS YP_002345762.1 218927887 1173540 758430..760910 1 NC_003143.1 outer membrane usher protein 760910 1173540 YPO0698 Yersinia pestis CO92 outer membrane usher protein YP_002345762.1 758430 D 214092 CDS YP_002345763.1 218927888 1173541 760928..761647 1 NC_003143.1 fimbrial chaperone protein 761647 1173541 YPO0699 Yersinia pestis CO92 fimbrial chaperone protein YP_002345763.1 760928 D 214092 CDS YP_002345764.1 218927889 1173542 761672..762778 1 NC_003143.1 fimbrial protein 762778 1173542 YPO0700 Yersinia pestis CO92 fimbrial protein YP_002345764.1 761672 D 214092 CDS YP_002345765.1 218927890 1173543 complement(762990..764003) 1 NC_003143.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter substrate-binding protein 764003 1173543 YPO0701 Yersinia pestis CO92 iron-enterobactin transporter substrate-binding protein YP_002345765.1 762990 R 214092 CDS YP_002345766.1 218927891 1173544 764925..765920 1 NC_003143.1 hypothetical protein 765920 1173544 YPO0702 Yersinia pestis CO92 hypothetical protein YP_002345766.1 764925 D 214092 CDS YP_002345767.1 218927892 1173545 complement(766012..766581) 1 NC_003143.1 lipoprotein 766581 1173545 YPO0703 Yersinia pestis CO92 lipoprotein YP_002345767.1 766012 R 214092 CDS YP_002345768.1 218927893 1173547 complement(768877..770010) 1 NC_003143.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 770010 flhB 1173547 flhB Yersinia pestis CO92 flagellar biosynthesis protein FlhB YP_002345768.1 768877 R 214092 CDS YP_002345769.1 218927894 1173548 complement(770010..770783) 1 NC_003143.1 flagellar assembly protein 770783 fliR 1173548 fliR Yersinia pestis CO92 flagellar assembly protein YP_002345769.1 770010 R 214092 CDS YP_002345770.1 218927895 1173549 complement(770790..771059) 1 NC_003143.1 flagellar assembly protein 771059 fliQ 1173549 fliQ Yersinia pestis CO92 flagellar assembly protein YP_002345770.1 770790 R 214092 CDS YP_002345771.1 218927896 1173550 complement(771064..771834) 1 NC_003143.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 771834 fliP 1173550 fliP Yersinia pestis CO92 flagellar biosynthesis protein FliP YP_002345771.1 771064 R 214092 CDS YP_002345772.1 218927897 1173551 complement(771831..772244) 1 NC_003143.1 flagellar switch protein 772244 fliN 1173551 fliN Yersinia pestis CO92 flagellar switch protein YP_002345772.1 771831 R 214092 CDS YP_002345773.1 218927898 1173552 complement(772237..773148) 1 NC_003143.1 flagellar motor switch protein 773148 fliM 1173552 fliM Yersinia pestis CO92 flagellar motor switch protein YP_002345773.1 772237 R 214092 CDS YP_002345774.1 218927899 1173553 773659..774687 1 NC_003143.1 Fis family transcriptional regulator 774687 flbD 1173553 flbD Yersinia pestis CO92 Fis family transcriptional regulator YP_002345774.1 773659 D 214092 CDS YP_002345775.1 218927900 1173554 774704..775084 1 NC_003143.1 flagellar hook-basal body complex protein 775084 fliE 1173554 fliE Yersinia pestis CO92 flagellar hook-basal body complex protein YP_002345775.1 774704 D 214092 CDS YP_002345776.1 218927901 1173555 775094..776734 1 NC_003143.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella; flagellar MS-ring protein 776734 fliF 1173555 fliF Yersinia pestis CO92 flagellar MS-ring protein YP_002345776.1 775094 D 214092 CDS YP_002345777.1 218927902 1173556 776706..777749 1 NC_003143.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 777749 fliG 1173556 fliG Yersinia pestis CO92 flagellar motor switch protein G YP_002345777.1 776706 D 214092 CDS YP_002345778.1 218927903 1173557 777751..778470 1 NC_003143.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 778470 fliH 1173557 fliH Yersinia pestis CO92 flagellar assembly protein H YP_002345778.1 777751 D 214092 CDS YP_002345779.1 218927904 1173558 778463..779803 1 NC_003143.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 779803 fliI 1173558 fliI Yersinia pestis CO92 flagellum-specific ATP synthase YP_002345779.1 778463 D 214092 CDS YP_002345780.1 218927905 1173559 779816..780190 1 NC_003143.1 no significant database hits. Glutamine rich protein, 22 out of the 124 amino acids are glutamine residues (22% of the protein); hypothetical protein 780190 1173559 YPO0718 Yersinia pestis CO92 hypothetical protein YP_002345780.1 779816 D 214092 CDS YP_002345781.2 537470137 1173560 complement(780518..780943) 1 NC_003143.1 hypothetical protein 780943 1173560 YPO0719 Yersinia pestis CO92 hypothetical protein YP_002345781.2 780518 R 214092 CDS YP_002345782.1 218927907 1173561 complement(780950..781216) 1 NC_003143.1 flagellar regulatory protein 781216 1173561 YPO0720 Yersinia pestis CO92 flagellar regulatory protein YP_002345782.1 780950 R 214092 CDS YP_002345783.2 537470138 1173562 complement(781445..782362) 1 NC_003143.1 required for the assembly of the flagellar basal body P-ring; the Vibrio parahaemolyticus protein involved with the synthesis of the lateral flagella; flagellar basal body P-ring biosynthesis protein FlgA 782362 flgA 1173562 flgA Yersinia pestis CO92 flagellar basal body P-ring biosynthesis protein FlgA YP_002345783.2 781445 R 214092 CDS YP_002345784.1 218927909 1173563 782351..782797 1 NC_003143.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Yersinia has 2 copies of flgB and other flagellar genes; flagellar basal-body rod protein FlgB 782797 flgB 1173563 flgB Yersinia pestis CO92 flagellar basal-body rod protein FlgB YP_002345784.1 782351 D 214092 CDS YP_002345785.1 218927910 1173564 782800..783225 1 NC_003143.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella; flagellar basal body rod protein FlgC 783225 flgC 1173564 flgC Yersinia pestis CO92 flagellar basal body rod protein FlgC YP_002345785.1 782800 D 214092 CDS YP_002345786.1 218927911 1173565 783228..783884 1 NC_003143.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Vibrio parahaemolyticus protein in this cluster is associated with lateral flagella production; flagellar basal body rod modification protein 783884 flgD 1173565 flgD Yersinia pestis CO92 flagellar basal body rod modification protein YP_002345786.1 783228 D 214092 CDS YP_002345787.1 218927912 1173566 783939..785180 1 NC_003143.1 the hook connects flagellar basal body to the flagellar filament; Vibrio parahaemolyticus protein is associated with the lateral flagella; flagellar hook protein FlgE 785180 flgE 1173566 flgE Yersinia pestis CO92 flagellar hook protein FlgE YP_002345787.1 783939 D 214092 CDS YP_002345788.1 218927913 1173568 complement(785404..785862) 1 NC_003143.1 transposase for the IS1541 insertion element 785862 tnp 1173568 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345788.1 785404 R 214092 CDS YP_002345789.1 218927914 1173569 786690..787475 1 NC_003143.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 787475 flgG 1173569 flgG Yersinia pestis CO92 flagellar basal body rod protein FlgG YP_002345789.1 786690 D 214092 CDS YP_002345790.1 218927915 1173570 787510..788175 1 NC_003143.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; the Yersinia have 2 copies of flgH; flagellar basal body L-ring protein 788175 flgH 1173570 flgH Yersinia pestis CO92 flagellar basal body L-ring protein YP_002345790.1 787510 D 214092 CDS YP_002345791.1 218927916 1173571 788252..789364 1 NC_003143.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 789364 flgI 1173571 flgI Yersinia pestis CO92 flagellar basal body P-ring biosynthesis protein FlgA YP_002345791.1 788252 D 214092 CDS YP_002345792.1 218927917 1173572 789374..789667 1 NC_003143.1 FlgJ; flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; like the lateral flagella FlgJ in Vibrio parahaemolyticus this protein does not contains a C-terminal muramidase domain; peptidoglycan hydrolase 789667 flgJ 1173572 flgJ Yersinia pestis CO92 peptidoglycan hydrolase YP_002345792.1 789374 D 214092 CDS YP_002345793.1 218927918 1173573 789780..791141 1 NC_003143.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 791141 flgK 1173573 flgK Yersinia pestis CO92 flagellar hook-associated protein FlgK YP_002345793.1 789780 D 214092 CDS YP_002345794.1 218927919 1173574 791170..792093 1 NC_003143.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; in Vibrio parahaemolyticus the protein in this cluster is associated with the lateral flagella; flagellar hook-associated protein FlgL 792093 flgL 1173574 flgL Yersinia pestis CO92 flagellar hook-associated protein FlgL YP_002345794.1 791170 D 214092 CDS YP_002345795.1 218927920 1173575 792138..793118 1 NC_003143.1 hypothetical protein 793118 1173575 YPO0734 Yersinia pestis CO92 hypothetical protein YP_002345795.1 792138 D 214092 CDS YP_002345796.2 537470139 1173576 complement(793282..793728) 1 NC_003143.1 hypothetical protein 793728 1173576 YPO0735 Yersinia pestis CO92 hypothetical protein YP_002345796.2 793282 R 214092 CDS YP_002345797.1 218927922 1173577 complement(793709..794755) 1 NC_003143.1 regulatory protein 794755 1173577 YPO0736 Yersinia pestis CO92 regulatory protein YP_002345797.1 793709 R 214092 CDS YP_002345798.1 218927923 1173578 795381..796595 1 NC_003143.1 flagellin 796595 flaA1 1173578 flaA1 Yersinia pestis CO92 flagellin YP_002345798.1 795381 D 214092 CDS YP_002345799.1 218927924 1173579 797110..798309 1 NC_003143.1 flagellin 798309 flaA2 1173579 flaA2 Yersinia pestis CO92 flagellin YP_002345799.1 797110 D 214092 CDS YP_002345800.1 218927925 1173580 798592..799797 1 NC_003143.1 flagellin 799797 flaA3 1173580 flaA3 Yersinia pestis CO92 flagellin YP_002345800.1 798592 D 214092 CDS YP_002345801.1 218927926 1173581 800017..801294 1 NC_003143.1 flagellar hook-associated protein 801294 fliD 1173581 fliD Yersinia pestis CO92 flagellar hook-associated protein YP_002345801.1 800017 D 214092 CDS YP_002345802.1 218927927 1173582 801304..801684 1 NC_003143.1 flagellar protein 801684 fliS 1173582 fliS Yersinia pestis CO92 flagellar protein YP_002345802.1 801304 D 214092 CDS YP_002345803.1 218927928 1173583 801686..802012 1 NC_003143.1 hypothetical protein 802012 1173583 YPO0742 Yersinia pestis CO92 hypothetical protein YP_002345803.1 801686 D 214092 CDS YP_002345804.1 218927929 1173584 802014..803195 1 NC_003143.1 flagellar hook-length control protein 803195 1173584 YPO0743 Yersinia pestis CO92 flagellar hook-length control protein YP_002345804.1 802014 D 214092 CDS YP_002345805.1 218927930 1173585 803234..803704 1 NC_003143.1 flagellar biogenesis protein 803704 1173585 YPO0744 Yersinia pestis CO92 flagellar biogenesis protein YP_002345805.1 803234 D 214092 CDS YP_002345806.1 218927931 1173586 803710..804405 1 NC_003143.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 804405 fliA 1173586 fliA Yersinia pestis CO92 flagellar biosynthesis sigma factor YP_002345806.1 803710 D 214092 CDS YP_002345807.1 218927932 1173587 804421..805287 1 NC_003143.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 805287 motA 1173587 motA Yersinia pestis CO92 flagellar motor protein MotA YP_002345807.1 804421 D 214092 CDS YP_002345808.1 218927933 1173588 805287..806198 1 NC_003143.1 hypothetical protein 806198 motB 1173588 motB Yersinia pestis CO92 hypothetical protein YP_002345808.1 805287 D 214092 CDS YP_002345810.1 218927935 1173590 806658..807254 1 NC_003143.1 hypothetical protein 807254 1173590 YPO0749 Yersinia pestis CO92 hypothetical protein YP_002345810.1 806658 D 214092 CDS YP_002345811.1 218927936 1173591 807251..807706 1 NC_003143.1 hypothetical protein 807706 1173591 YPO0750 Yersinia pestis CO92 hypothetical protein YP_002345811.1 807251 D 214092 CDS YP_002345812.2 537470140 1173592 807690..808061 1 NC_003143.1 hypothetical protein 808061 1173592 YPO0751 Yersinia pestis CO92 hypothetical protein YP_002345812.2 807690 D 214092 CDS YP_002345813.1 218927938 1173594 complement(808939..809241) 1 NC_003143.1 hypothetical protein 809241 1173594 YPO0754 Yersinia pestis CO92 hypothetical protein YP_002345813.1 808939 R 214092 CDS YP_002345814.1 218927939 1173595 809842..810357 1 NC_003143.1 insertion element DNA-binding protein 810357 1173595 YPO0755 Yersinia pestis CO92 insertion element DNA-binding protein YP_002345814.1 809842 D 214092 CDS YP_002345815.1 218927940 1173596 810411..811196 1 NC_003143.1 transposase for insertion sequence IS1661 811196 1173596 YPO0756 Yersinia pestis CO92 transposase for insertion sequence IS1661 YP_002345815.1 810411 D 214092 CDS YP_008479683.1 537470141 1173597 complement(811086..812249) 1 NC_003143.1 hypothetical protein 812249 1173597 YPO0757 Yersinia pestis CO92 hypothetical protein YP_008479683.1 811086 R 214092 CDS YP_002345816.1 218927941 1173598 812567..813562 1 NC_003143.1 LacI family regulatory protein 813562 1173598 YPO0758 Yersinia pestis CO92 LacI family regulatory protein YP_002345816.1 812567 D 214092 CDS YP_002345817.1 218927942 1173599 813844..815214 1 NC_003143.1 sodium:sulfate symporter family protein 815214 1173599 YPO0759 Yersinia pestis CO92 sodium:sulfate symporter family protein YP_002345817.1 813844 D 214092 CDS YP_002345818.1 218927943 1173600 complement(815394..815807) 1 NC_003143.1 hypothetical protein 815807 1173600 YPO0760 Yersinia pestis CO92 hypothetical protein YP_002345818.1 815394 R 214092 CDS YP_002345819.1 218927944 1173601 complement(816351..816593) 1 NC_003143.1 no significant database hits; hypothetical protein 816593 1173601 YPO0761 Yersinia pestis CO92 hypothetical protein YP_002345819.1 816351 R 214092 CDS YP_002345820.1 218927945 1173602 complement(816868..821184) 1 NC_003143.1 hypothetical protein 821184 1173602 YPO0762 Yersinia pestis CO92 hypothetical protein YP_002345820.1 816868 R 214092 CDS YP_002345821.1 218927946 1173603 complement(821198..822517) 1 NC_003143.1 hypothetical protein 822517 1173603 YPO0763 Yersinia pestis CO92 hypothetical protein YP_002345821.1 821198 R 214092 CDS YP_002345822.1 218927947 1173604 complement(822543..824768) 1 NC_003143.1 hypothetical protein 824768 1173604 YPO0764 Yersinia pestis CO92 hypothetical protein YP_002345822.1 822543 R 214092 CDS YP_002345823.1 218927948 1173606 complement(830118..831461) 1 NC_003143.1 fructuronate transporter 831461 gntP 1173606 gntP Yersinia pestis CO92 fructuronate transporter YP_002345823.1 830118 R 214092 CDS YP_002345824.1 218927949 1173607 833001..833399 1 NC_003143.1 no significant database hits; hypothetical protein 833399 1173607 YPO0768 Yersinia pestis CO92 hypothetical protein YP_002345824.1 833001 D 214092 CDS YP_002345825.1 218927950 1173608 833835..834710 1 NC_003143.1 hypothetical protein 834710 1173608 YPO0769 Yersinia pestis CO92 hypothetical protein YP_002345825.1 833835 D 214092 CDS YP_002345826.1 218927951 1173609 complement(835033..836790) 1 NC_003143.1 ABC transporter transmembrane protein 836790 1173609 YPO0770 Yersinia pestis CO92 ABC transporter transmembrane protein YP_002345826.1 835033 R 214092 CDS YP_002345827.1 218927952 1173610 complement(836783..838555) 1 NC_003143.1 ABC transporter transmembrane protein 838555 1173610 YPO0771 Yersinia pestis CO92 ABC transporter transmembrane protein YP_002345827.1 836783 R 214092 CDS YP_002345828.1 218927953 1173611 complement(838555..839859) 1 NC_003143.1 hypothetical protein 839859 1173611 YPO0772 Yersinia pestis CO92 hypothetical protein YP_002345828.1 838555 R 214092 CDS YP_002345829.1 218927954 1173612 complement(839849..840613) 1 NC_003143.1 thioesterase 840613 1173612 YPO0773 Yersinia pestis CO92 thioesterase YP_002345829.1 839849 R 214092 CDS YP_002345830.1 218927955 1173613 complement(840606..841733) 1 NC_003143.1 hypothetical protein 841733 1173613 YPO0774 Yersinia pestis CO92 hypothetical protein YP_002345830.1 840606 R 214092 CDS YP_002345831.1 218927956 1173614 complement(841730..842806) 1 NC_003143.1 hypothetical protein 842806 1173614 YPO0775 Yersinia pestis CO92 hypothetical protein YP_002345831.1 841730 R 214092 CDS YP_002345832.1 218927957 1173615 complement(842803..848622) 1 NC_003143.1 siderophore biosysnthesis protein 848622 1173615 YPO0776 Yersinia pestis CO92 siderophore biosysnthesis protein YP_002345832.1 842803 R 214092 CDS YP_002345833.1 218927958 1173616 complement(848635..850287) 1 NC_003143.1 siderophore biosysnthesis protein 850287 1173616 YPO0777 Yersinia pestis CO92 siderophore biosysnthesis protein YP_002345833.1 848635 R 214092 CDS YP_002345834.1 218927959 1173617 complement(850331..856936) 1 NC_003143.1 siderophore biosysnthesis protein 856936 1173617 YPO0778 Yersinia pestis CO92 siderophore biosysnthesis protein YP_002345834.1 850331 R 214092 CDS YP_002345835.1 218927960 1173618 complement(856997..857779) 1 NC_003143.1 transposase/IS protein 857779 1173618 YPO0779 Yersinia pestis CO92 transposase/IS protein YP_002345835.1 856997 R 214092 CDS YP_002345836.1 218927961 1173619 complement(857776..858798) 1 NC_003143.1 transposase for insertion sequence IS100 858798 y1093 1173619 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002345836.1 857776 R 214092 CDS YP_002345838.1 218927963 1173622 complement(859517..860311) 1 NC_003143.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 860311 thyA 1173622 thyA Yersinia pestis CO92 thymidylate synthase YP_002345838.1 859517 R 214092 CDS YP_002345839.1 218927964 1173623 complement(860318..861190) 1 NC_003143.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 861190 lgt 1173623 lgt Yersinia pestis CO92 prolipoprotein diacylglyceryl transferase YP_002345839.1 860318 R 214092 CDS YP_002345840.1 218927965 1173624 complement(861441..863687) 1 NC_003143.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain-containing protein 863687 ptsP 1173624 ptsP Yersinia pestis CO92 fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain-containing protein YP_002345840.1 861441 R 214092 CDS YP_002345841.1 218927966 1173625 complement(863700..864227) 1 NC_003143.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 864227 1173625 YPO0786 Yersinia pestis CO92 dinucleoside polyphosphate hydrolase YP_002345841.1 863700 R 214092 CDS YP_002345844.1 218927969 1173628 864925..865611 1 NC_003143.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 865611 mutH 1173628 mutH Yersinia pestis CO92 DNA mismatch repair protein YP_002345844.1 864925 D 214092 CDS YP_002345845.1 218927970 1173629 865946..866986 1 NC_003143.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo/keto reductase 866986 tas 1173629 tas Yersinia pestis CO92 aldo/keto reductase YP_002345845.1 865946 D 214092 CDS YP_008479684.1 537470142 16744741 867693..867926 1 NC_003143.1 hypothetical protein 867926 16744741 YPO0790a Yersinia pestis CO92 hypothetical protein YP_008479684.1 867693 D 214092 CDS YP_002345847.1 218927972 1173631 complement(867955..869175) 1 NC_003143.1 lysophospholipid transporter LplT 869175 ygeD 1173631 ygeD Yersinia pestis CO92 lysophospholipid transporter LplT YP_002345847.1 867955 R 214092 CDS YP_002345848.1 218927973 1173632 complement(869172..871328) 1 NC_003143.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; acyl-ACP synthetase 871328 aas 1173632 aas Yersinia pestis CO92 acyl-ACP synthetase YP_002345848.1 869172 R 214092 CDS YP_002345849.1 218927974 1173633 complement(871777..874038) 1 NC_003143.1 biotin sulfoxide reductas2 874038 bisC 1173633 bisC Yersinia pestis CO92 biotin sulfoxide reductas2 YP_002345849.1 871777 R 214092 CDS YP_002345850.1 218927975 1173634 874348..875370 1 NC_003143.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 875370 galR 1173634 galR Yersinia pestis CO92 DNA-binding transcriptional regulator GalR YP_002345850.1 874348 D 214092 CDS YP_002345851.1 218927976 1173635 complement(875367..876629) 1 NC_003143.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 876629 lysA 1173635 lysA Yersinia pestis CO92 diaminopimelate decarboxylase YP_002345851.1 875367 R 214092 CDS YP_002345852.1 218927977 1173636 876844..877785 1 NC_003143.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; LysR family transcriptional regulator 877785 lysR 1173636 lysR Yersinia pestis CO92 LysR family transcriptional regulator YP_002345852.1 876844 D 214092 CDS YP_002345853.1 218927978 1173637 complement(877782..878942) 1 NC_003143.1 sugar transport protein 878942 1173637 YPO0798 Yersinia pestis CO92 sugar transport protein YP_002345853.1 877782 R 214092 CDS YP_002345854.1 218927979 1173638 complement(879311..880219) 1 NC_003143.1 LysR family transcriptional regulator 880219 1173638 YPO0799 Yersinia pestis CO92 LysR family transcriptional regulator YP_002345854.1 879311 R 214092 CDS YP_002345855.1 218927980 1173639 880326..881213 1 NC_003143.1 hypothetical protein 881213 1173639 YPO0800 Yersinia pestis CO92 hypothetical protein YP_002345855.1 880326 D 214092 CDS YP_002345856.1 218927981 1173640 881326..881961 1 NC_003143.1 hypothetical protein 881961 1173640 YPO0801 Yersinia pestis CO92 hypothetical protein YP_002345856.1 881326 D 214092 CDS YP_002345857.1 218927982 1173641 complement(881947..883590) 1 NC_003143.1 methyl-accepting chemotaxis protein 883590 cheD 1173641 cheD Yersinia pestis CO92 methyl-accepting chemotaxis protein YP_002345857.1 881947 R 214092 CDS YP_002345858.1 218927983 1173642 complement(883793..884194) 1 NC_003143.1 no significant database hits; hypothetical protein 884194 1173642 YPO0803 Yersinia pestis CO92 hypothetical protein YP_002345858.1 883793 R 214092 CDS YP_002345859.1 218927984 1173643 complement(884191..884907) 1 NC_003143.1 regulatory membrane protein 884907 1173643 YPO0804 Yersinia pestis CO92 regulatory membrane protein YP_002345859.1 884191 R 214092 CDS YP_002345860.1 218927985 1173644 885191..885496 1 NC_003143.1 lipoprotein 885496 1173644 YPO0805 Yersinia pestis CO92 lipoprotein YP_002345860.1 885191 D 214092 CDS YP_002345861.1 218927986 1173645 complement(885548..886390) 1 NC_003143.1 prepilin peptidase 886390 1173645 YPO0806 Yersinia pestis CO92 prepilin peptidase YP_002345861.1 885548 R 214092 CDS YP_002345863.1 218927988 1173647 complement(886874..888043) 1 NC_003143.1 general secretion pathway protein L 888043 1173647 YPO0808 Yersinia pestis CO92 general secretion pathway protein L YP_002345863.1 886874 R 214092 CDS YP_002345864.1 218927989 1173648 complement(888048..889004) 1 NC_003143.1 general secretion pathway protein K 889004 1173648 YPO0809 Yersinia pestis CO92 general secretion pathway protein K YP_002345864.1 888048 R 214092 CDS YP_002345865.1 218927990 1173649 complement(889013..889609) 1 NC_003143.1 general secretion pathway protein J 889609 1173649 YPO0810 Yersinia pestis CO92 general secretion pathway protein J YP_002345865.1 889013 R 214092 CDS YP_002345866.1 218927991 1173650 complement(889602..889946) 1 NC_003143.1 general secretion pathway protein I 889946 1173650 YPO0811 Yersinia pestis CO92 general secretion pathway protein I YP_002345866.1 889602 R 214092 CDS YP_002345867.1 218927992 1173651 complement(889984..890526) 1 NC_003143.1 general secretion pathway protein H 890526 1173651 YPO0812 Yersinia pestis CO92 general secretion pathway protein H YP_002345867.1 889984 R 214092 CDS YP_002345868.1 218927993 1173652 complement(890531..890968) 1 NC_003143.1 general secretion pathway protein G 890968 1173652 YPO0813 Yersinia pestis CO92 general secretion pathway protein G YP_002345868.1 890531 R 214092 CDS YP_008479685.1 537470143 1173653 complement(890988..892004) 1 NC_003143.1 type II secretion system protein 892004 1173653 YPO0814 Yersinia pestis CO92 type II secretion system protein YP_008479685.1 890988 R 214092 CDS YP_002345869.1 218927994 1173654 complement(892176..893687) 1 NC_003143.1 general secretion pathway protein E 893687 1173654 YPO0815 Yersinia pestis CO92 general secretion pathway protein E YP_002345869.1 892176 R 214092 CDS YP_002345870.1 218927995 1173655 complement(893684..895606) 1 NC_003143.1 general secretion pathway protein D 895606 1173655 YPO0816 Yersinia pestis CO92 general secretion pathway protein D YP_002345870.1 893684 R 214092 CDS YP_002345871.1 218927996 1173656 complement(895687..896190) 1 NC_003143.1 general secretion pathway protein C 896190 1173656 YPO0817 Yersinia pestis CO92 general secretion pathway protein C YP_002345871.1 895687 R 214092 CDS YP_002345872.1 218927997 1173657 complement(896258..896674) 1 NC_003143.1 hypothetical protein 896674 1173657 YPO0818 Yersinia pestis CO92 hypothetical protein YP_002345872.1 896258 R 214092 CDS YP_002345873.1 218927998 1173658 complement(897417..898172) 1 NC_003143.1 carbonic anhydrase 898172 1173658 YPO0819 Yersinia pestis CO92 carbonic anhydrase YP_002345873.1 897417 R 214092 CDS YP_002345874.1 218927999 1173659 898548..898856 1 NC_003143.1 no significant database hits; hypothetical protein 898856 1173659 YPO0820 Yersinia pestis CO92 hypothetical protein YP_002345874.1 898548 D 214092 CDS YP_002345876.1 218928001 1173661 899459..900409 1 NC_003143.1 hypothetical protein 900409 1173661 YPO0822 Yersinia pestis CO92 hypothetical protein YP_002345876.1 899459 D 214092 CDS YP_002345877.1 218928002 1173662 900524..902710 1 NC_003143.1 hypothetical protein 902710 1173662 YPO0823 Yersinia pestis CO92 hypothetical protein YP_002345877.1 900524 D 214092 CDS YP_002345878.1 218928003 1173663 902780..905893 1 NC_003143.1 hypothetical protein 905893 1173663 YPO0824 Yersinia pestis CO92 hypothetical protein YP_002345878.1 902780 D 214092 CDS YP_002345879.1 218928004 1173665 complement(906238..907020) 1 NC_003143.1 transposase/IS protein 907020 1173665 YPO0825 Yersinia pestis CO92 transposase/IS protein YP_002345879.1 906238 R 214092 CDS YP_002345880.1 218928005 1173666 complement(907017..908039) 1 NC_003143.1 transposase for insertion sequence IS100 908039 y1093 1173666 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002345880.1 907017 R 214092 CDS YP_008479686.1 537470144 16744742 908096..908530 1 NC_003143.1 transposase 908530 16744742 YPO828a Yersinia pestis CO92 transposase YP_008479686.1 908096 D 214092 CDS YP_002345881.1 218928006 1173667 complement(908982..910535) 1 NC_003143.1 sulfatase 910535 1173667 YPO0829 Yersinia pestis CO92 sulfatase YP_002345881.1 908982 R 214092 CDS YP_002345882.1 218928007 1173668 911375..912151 1 NC_003143.1 DeoR family regulatory protein 912151 1173668 YPO0831 Yersinia pestis CO92 DeoR family regulatory protein YP_002345882.1 911375 D 214092 CDS YP_002345883.1 218928008 1173669 912201..913499 1 NC_003143.1 tagatose 6-phosphate kinase 913499 agaZ 1173669 agaZ Yersinia pestis CO92 tagatose 6-phosphate kinase YP_002345883.1 912201 D 214092 CDS YP_002345884.1 218928009 1173670 913496..914662 1 NC_003143.1 phosphosugar isomerase 914662 1173670 YPO0833 Yersinia pestis CO92 phosphosugar isomerase YP_002345884.1 913496 D 214092 CDS YP_002345885.1 218928010 1173671 914680..915177 1 NC_003143.1 PTS transport protein 915177 manX 1173671 manX Yersinia pestis CO92 PTS transport protein YP_002345885.1 914680 D 214092 CDS YP_002345886.1 218928011 1173672 915224..916012 1 NC_003143.1 PTS permease 916012 1173672 YPO0835 Yersinia pestis CO92 PTS permease YP_002345886.1 915224 D 214092 CDS YP_002345887.1 218928012 1173673 916002..916892 1 NC_003143.1 PTS permease 916892 1173673 YPO0836 Yersinia pestis CO92 PTS permease YP_002345887.1 916002 D 214092 CDS YP_002345888.1 218928013 1173674 916978..917418 1 NC_003143.1 PTS permease 917418 1173674 YPO0837 Yersinia pestis CO92 PTS permease YP_002345888.1 916978 D 214092 CDS YP_002345889.1 218928014 1173675 917421..918587 1 NC_003143.1 acetylglucosamine-6-phosphate deacetylase 918587 1173675 YPO0838 Yersinia pestis CO92 acetylglucosamine-6-phosphate deacetylase YP_002345889.1 917421 D 214092 CDS YP_002345890.1 218928015 1173676 918783..919538 1 NC_003143.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 919538 kduD2 1173676 kduD2 Yersinia pestis CO92 2-deoxy-D-gluconate 3-dehydrogenase YP_002345890.1 918783 D 214092 CDS YP_002345891.1 218928016 1173677 919554..920612 1 NC_003143.1 hypothetical protein 920612 1173677 YPO0840 Yersinia pestis CO92 hypothetical protein YP_002345891.1 919554 D 214092 CDS YP_002345892.1 218928017 1173678 920856..922082 1 NC_003143.1 regulatory protein 922082 1173678 YPO0841 Yersinia pestis CO92 regulatory protein YP_002345892.1 920856 D 214092 CDS YP_002345893.1 218928018 1173679 922103..923710 1 NC_003143.1 sulfatase 923710 1173679 YPO0842 Yersinia pestis CO92 sulfatase YP_002345893.1 922103 D 214092 CDS YP_002345894.1 218928019 1173680 923833..925320 1 NC_003143.1 hypothetical protein 925320 1173680 YPO0843 Yersinia pestis CO92 hypothetical protein YP_002345894.1 923833 D 214092 CDS YP_002345895.1 218928020 1173681 925429..926283 1 NC_003143.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 926283 gatY 1173681 gatY Yersinia pestis CO92 tagatose-bisphosphate aldolase YP_002345895.1 925429 D 214092 CDS YP_002345896.1 218928021 1173682 926307..926885 1 NC_003143.1 ThiJ/PfpI family thiamine biogenesis protein 926885 1173682 YPO0845 Yersinia pestis CO92 ThiJ/PfpI family thiamine biogenesis protein YP_002345896.1 926307 D 214092 CDS YP_002345897.1 218928022 1173683 complement(927126..928208) 1 NC_003143.1 LacI family regulatory protein 928208 1173683 YPO0846 Yersinia pestis CO92 LacI family regulatory protein YP_002345897.1 927126 R 214092 CDS YP_002345898.1 218928023 1173684 928602..929909 1 NC_003143.1 sugar transporter 929909 1173684 YPO0847 Yersinia pestis CO92 sugar transporter YP_002345898.1 928602 D 214092 CDS YP_002345899.1 218928024 1173685 930057..932435 1 NC_003143.1 glucosidase 932435 1173685 YPO0848 Yersinia pestis CO92 glucosidase YP_002345899.1 930057 D 214092 CDS YP_002345900.1 218928025 1173686 complement(932764..933837) 1 NC_003143.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer; lac repressor 933837 lacI 1173686 lacI Yersinia pestis CO92 lac repressor YP_002345900.1 932764 R 214092 CDS YP_002345901.1 218928026 1173687 934109..935368 1 NC_003143.1 porin involved in the transport of maltose and maltodextrins; maltoporin 935368 lamB 1173687 lamB Yersinia pestis CO92 maltoporin YP_002345901.1 934109 D 214092 CDS YP_008853944.1 559797719 17699567 complement(935741..936052) 1 NC_003143.1 PTS system glucose/sucrose specific transporter subunit IIB 936052 17699567 YPO0850a Yersinia pestis CO92 PTS system glucose/sucrose specific transporter subunit IIB YP_008853944.1 935741 R 214092 CDS YP_002345903.1 218928028 1173689 complement(936164..938224) 1 NC_003143.1 beta-galactosidase 938224 bgaB 1173689 bgaB Yersinia pestis CO92 beta-galactosidase YP_002345903.1 936164 R 214092 CDS YP_002345904.1 218928029 1173690 complement(938275..939477) 1 NC_003143.1 galactosidase 939477 1173690 YPO0853 Yersinia pestis CO92 galactosidase YP_002345904.1 938275 R 214092 CDS YP_002345905.1 218928030 1173691 complement(939482..940333) 1 NC_003143.1 maltodextrin permease 940333 1173691 YPO0854 Yersinia pestis CO92 maltodextrin permease YP_002345905.1 939482 R 214092 CDS YP_002345906.1 218928031 1173692 complement(940345..941652) 1 NC_003143.1 maltodextrin ABC transporter permease 941652 1173692 YPO0855 Yersinia pestis CO92 maltodextrin ABC transporter permease YP_002345906.1 940345 R 214092 CDS YP_002345907.1 218928032 1173693 complement(941812..943074) 1 NC_003143.1 sugar-binding protein 943074 1173693 YPO0856 Yersinia pestis CO92 sugar-binding protein YP_002345907.1 941812 R 214092 CDS YP_002345908.1 218928033 1173694 943410..944510 1 NC_003143.1 sugar transport ATP-binding protein 944510 1173694 YPO0857 Yersinia pestis CO92 sugar transport ATP-binding protein YP_002345908.1 943410 D 214092 CDS YP_002345909.1 218928034 1173695 945059..946567 1 NC_003143.1 sugar transport ATP-binding protein 946567 1173695 YPO0858 Yersinia pestis CO92 sugar transport ATP-binding protein YP_002345909.1 945059 D 214092 CDS YP_002345910.1 218928035 1173696 946633..947643 1 NC_003143.1 sugar transport system permease 947643 1173696 YPO0859 Yersinia pestis CO92 sugar transport system permease YP_002345910.1 946633 D 214092 CDS YP_002345911.1 218928036 1173697 948078..949079 1 NC_003143.1 sugar-binding protein 949079 1173697 YPO0860 Yersinia pestis CO92 sugar-binding protein YP_002345911.1 948078 D 214092 CDS YP_002345912.1 218928037 1173698 949858..950376 1 NC_003143.1 No significant database matches to the full length CDS; hypothetical protein 950376 1173698 YPO0862 Yersinia pestis CO92 hypothetical protein YP_002345912.1 949858 D 214092 CDS YP_002345913.1 218928038 1173699 950752..951609 1 NC_003143.1 hypothetical protein 951609 1173699 YPO0863 Yersinia pestis CO92 hypothetical protein YP_002345913.1 950752 D 214092 CDS YP_002345914.1 218928039 1173700 952033..952713 1 NC_003143.1 hypothetical protein 952713 1173700 YPO0864 Yersinia pestis CO92 hypothetical protein YP_002345914.1 952033 D 214092 CDS YP_002345915.1 218928040 1173701 952713..953033 1 NC_003143.1 no significant database hits; hypothetical protein 953033 1173701 YPO0865 Yersinia pestis CO92 hypothetical protein YP_002345915.1 952713 D 214092 CDS YP_002345916.1 218928041 1173702 complement(953116..953421) 1 NC_003143.1 hypothetical protein 953421 1173702 YPO0866 Yersinia pestis CO92 hypothetical protein YP_002345916.1 953116 R 214092 CDS YP_002345917.1 218928042 1173703 complement(953638..954417) 1 NC_003143.1 hypothetical protein 954417 1173703 YPO0867 Yersinia pestis CO92 hypothetical protein YP_002345917.1 953638 R 214092 CDS YP_002345919.1 218928044 1173705 complement(955022..955738) 1 NC_003143.1 hypothetical protein 955738 1173705 YPO0869 Yersinia pestis CO92 hypothetical protein YP_002345919.1 955022 R 214092 CDS YP_002345920.1 218928045 1173706 complement(955759..958083) 1 NC_003143.1 hypothetical protein 958083 1173706 YPO0870 Yersinia pestis CO92 hypothetical protein YP_002345920.1 955759 R 214092 CDS YP_002345921.1 218928046 1173707 complement(958328..958612) 1 NC_003143.1 colicin immunity protein 958612 1173707 YPO0871 Yersinia pestis CO92 colicin immunity protein YP_002345921.1 958328 R 214092 CDS YP_002345922.1 218928047 1173708 complement(958659..958916) 1 NC_003143.1 hypothetical protein 958916 1173708 YPO0872 Yersinia pestis CO92 hypothetical protein YP_002345922.1 958659 R 214092 CDS YP_002345923.1 218928048 1173709 complement(959426..960964) 1 NC_003143.1 hypothetical protein 960964 1173709 YPO0873 Yersinia pestis CO92 hypothetical protein YP_002345923.1 959426 R 214092 CDS YP_002345924.1 218928049 1173710 complement(961468..962610) 1 NC_003143.1 hypothetical protein 962610 1173710 YPO0874 Yersinia pestis CO92 hypothetical protein YP_002345924.1 961468 R 214092 CDS YP_002345925.1 218928050 1173711 962879..963244 1 NC_003143.1 hypothetical protein 963244 1173711 YPO0875 Yersinia pestis CO92 hypothetical protein YP_002345925.1 962879 D 214092 CDS YP_002345928.1 218928053 1173714 964013..964213 1 NC_003143.1 regulatory protein 964213 1173714 YPO0878 Yersinia pestis CO92 regulatory protein YP_002345928.1 964013 D 214092 CDS YP_002345929.1 218928054 1173715 complement(964372..964698) 1 NC_003143.1 hypothetical protein 964698 1173715 YPO0879 Yersinia pestis CO92 hypothetical protein YP_002345929.1 964372 R 214092 CDS YP_002345930.1 218928055 1173716 964998..967289 1 NC_003143.1 primase 967289 1173716 YPO0880 Yersinia pestis CO92 primase YP_002345930.1 964998 D 214092 CDS YP_002345931.1 218928056 1173717 complement(967689..968087) 1 NC_003143.1 hypothetical protein 968087 1173717 YPO0881 Yersinia pestis CO92 hypothetical protein YP_002345931.1 967689 R 214092 CDS YP_002345932.1 218928057 1173718 complement(968087..968383) 1 NC_003143.1 hypothetical protein 968383 1173718 YPO0882 Yersinia pestis CO92 hypothetical protein YP_002345932.1 968087 R 214092 CDS YP_002345933.1 218928058 1173719 complement(968547..968909) 1 NC_003143.1 DNA binding protein 968909 1173719 YPO0883 Yersinia pestis CO92 DNA binding protein YP_002345933.1 968547 R 214092 CDS YP_002345934.1 218928059 1173720 complement(968972..969232) 1 NC_003143.1 hypothetical protein 969232 1173720 YPO0884 Yersinia pestis CO92 hypothetical protein YP_002345934.1 968972 R 214092 CDS YP_002345935.1 218928060 1173722 complement(970097..971311) 1 NC_003143.1 integrase 971311 int 1173722 int Yersinia pestis CO92 integrase YP_002345935.1 970097 R 214092 CDS YP_002345936.1 218928061 1173724 complement(971744..973261) 1 NC_003143.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 973261 lysS 1173724 lysS Yersinia pestis CO92 lysyl-tRNA synthetase YP_002345936.1 971744 R 214092 CDS YP_002345937.1 218928062 1173725 complement(join(973271..974293,974295..974369)) 1 NC_003143.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 974369 prfB 1173725 prfB Yersinia pestis CO92 peptide chain release factor 2 YP_002345937.1 973271 R 214092 CDS YP_002345938.1 218928063 1173726 complement(974548..976281) 1 NC_003143.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 976281 recJ 1173726 recJ Yersinia pestis CO92 ssDNA exonuclease RecJ YP_002345938.1 974548 R 214092 CDS YP_002345939.1 218928064 1173727 complement(976288..977004) 1 NC_003143.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 977004 dsbC 1173727 dsbC Yersinia pestis CO92 thiol:disulfide interchange protein DsbC YP_002345939.1 976288 R 214092 CDS YP_002345940.1 218928065 1173728 complement(977035..977934) 1 NC_003143.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 977934 xerD 1173728 xerD Yersinia pestis CO92 site-specific tyrosine recombinase XerD YP_002345940.1 977035 R 214092 CDS YP_002345941.1 218928066 1173729 978041..978559 1 NC_003143.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 978559 fldB 1173729 fldB Yersinia pestis CO92 flavodoxin FldB YP_002345941.1 978041 D 214092 CDS YP_002345942.1 218928067 1173730 complement(978649..980127) 1 NC_003143.1 hypothetical protein 980127 creD 1173730 creD Yersinia pestis CO92 hypothetical protein YP_002345942.1 978649 R 214092 CDS YP_002345943.1 218928068 1173731 complement(980227..981645) 1 NC_003143.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 981645 creC 1173731 creC Yersinia pestis CO92 sensory histidine kinase CreC YP_002345943.1 980227 R 214092 CDS YP_002345944.1 218928069 1173732 complement(981670..982371) 1 NC_003143.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 982371 creB 1173732 creB Yersinia pestis CO92 DNA-binding response regulator CreB YP_002345944.1 981670 R 214092 CDS YP_002345945.1 218928070 1173733 complement(982368..982793) 1 NC_003143.1 hypothetical protein 982793 1173733 YPO0896a Yersinia pestis CO92 hypothetical protein YP_002345945.1 982368 R 214092 CDS YP_002345946.1 218928071 1173734 complement(982774..983040) 1 NC_003143.1 hypothetical protein 983040 1173734 YPO0897 Yersinia pestis CO92 hypothetical protein YP_002345946.1 982774 R 214092 CDS YP_002345947.1 218928072 1173735 983357..984349 1 NC_003143.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 984349 1173735 YPO0898 Yersinia pestis CO92 global regulator YP_002345947.1 983357 D 214092 CDS YP_002345948.1 218928073 1173736 complement(984422..984919) 1 NC_003143.1 hypothetical protein 984919 1173736 YPO0899 Yersinia pestis CO92 hypothetical protein YP_002345948.1 984422 R 214092 CDS YP_002345949.1 218928074 1173737 complement(985177..985878) 1 NC_003143.1 hemolysin III 985878 1173737 YPO0900 Yersinia pestis CO92 hemolysin III YP_002345949.1 985177 R 214092 CDS YP_002345950.1 218928075 1173738 complement(986080..987225) 1 NC_003143.1 No significant database matches. Similar to YPO1686 (61.0% identity in 354 aa overlap).; hypothetical protein 987225 1173738 YPO0901 Yersinia pestis CO92 hypothetical protein YP_002345950.1 986080 R 214092 CDS YP_002345952.1 218928077 1173740 complement(990473..990910) 1 NC_003143.1 no significant database hits; hypothetical protein 990910 1173740 YPO0904 Yersinia pestis CO92 hypothetical protein YP_002345952.1 990473 R 214092 CDS YP_002345953.1 218928078 1173741 complement(991288..994167) 1 NC_003143.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 994167 gcvP 1173741 gcvP Yersinia pestis CO92 glycine dehydrogenase YP_002345953.1 991288 R 214092 CDS YP_002345954.1 218928079 1173742 complement(994379..994765) 1 NC_003143.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 994765 gcsH 1173742 gcsH Yersinia pestis CO92 glycine cleavage system protein H YP_002345954.1 994379 R 214092 CDS YP_002345955.1 218928080 1173743 complement(994834..995931) 1 NC_003143.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 995931 gcvT 1173743 gcvT Yersinia pestis CO92 glycine cleavage system aminomethyltransferase T YP_002345955.1 994834 R 214092 CDS YP_002345956.1 218928081 1173744 complement(996652..997872) 1 NC_003143.1 hypothetical protein 997872 visC 1173744 visC Yersinia pestis CO92 hypothetical protein YP_002345956.1 996652 R 214092 CDS YP_002345957.1 218928082 1173745 complement(998045..999223) 1 NC_003143.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 999223 ubiH 1173745 ubiH Yersinia pestis CO92 2-octaprenyl-6-methoxyphenyl hydroxylase YP_002345957.1 998045 R 214092 CDS YP_002345958.1 218928083 1173746 complement(999292..1000605) 1 NC_003143.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 1000605 pepP 1173746 pepP Yersinia pestis CO92 proline aminopeptidase P II YP_002345958.1 999292 R 214092 CDS YP_002345959.1 218928084 1173747 complement(1000693..1001271) 1 NC_003143.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 1001271 1173747 YPO0911 Yersinia pestis CO92 hypothetical protein YP_002345959.1 1000693 R 214092 CDS YP_002345960.1 218928085 1173748 1001608..1001937 1 NC_003143.1 Z-ring-associated protein 1001937 1173748 YPO0912 Yersinia pestis CO92 Z-ring-associated protein YP_002345960.1 1001608 D 214092 CDS YP_002345961.1 218928086 1173750 1002301..1002897 1 NC_003143.1 5-formyltetrahydrofolate cyclo-ligase 1002897 1173750 YPO0913 Yersinia pestis CO92 5-formyltetrahydrofolate cyclo-ligase YP_002345961.1 1002301 D 214092 CDS YP_002345962.1 218928087 1173751 complement(1003162..1004403) 1 NC_003143.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1004403 serA 1173751 serA Yersinia pestis CO92 D-3-phosphoglycerate dehydrogenase YP_002345962.1 1003162 R 214092 CDS YP_002345963.1 218928088 1173752 complement(1004710..1005366) 1 NC_003143.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 1005366 rpiA 1173752 rpiA Yersinia pestis CO92 ribose-5-phosphate isomerase A YP_002345963.1 1004710 R 214092 CDS YP_002345964.1 218928089 1173753 1005708..1006616 1 NC_003143.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 1006616 iciA 1173753 iciA Yersinia pestis CO92 chromosome replication initiation inhibitor protein YP_002345964.1 1005708 D 214092 CDS YP_002345965.1 218928090 1173754 complement(1006627..1007406) 1 NC_003143.1 hypothetical protein 1007406 yggE 1173754 yggE Yersinia pestis CO92 hypothetical protein YP_002345965.1 1006627 R 214092 CDS YP_002345966.1 218928091 1173755 complement(1007596..1008213) 1 NC_003143.1 Involved in the export of arginine; arginine exporter protein 1008213 yggA 1173755 yggA Yersinia pestis CO92 arginine exporter protein YP_002345966.1 1007596 R 214092 CDS YP_002345967.1 218928092 1173756 complement(1008476..1009345) 1 NC_003143.1 hypothetical protein 1009345 1173756 YPO0919 Yersinia pestis CO92 hypothetical protein YP_002345967.1 1008476 R 214092 CDS YP_002345968.1 218928093 1173757 complement(1009783..1010862) 1 NC_003143.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 1010862 fbaA 1173757 fbaA Yersinia pestis CO92 fructose-bisphosphate aldolase YP_002345968.1 1009783 R 214092 CDS YP_002345969.1 218928094 1173758 complement(1010982..1012145) 1 NC_003143.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1012145 pgk 1173758 pgk Yersinia pestis CO92 phosphoglycerate kinase YP_002345969.1 1010982 R 214092 CDS YP_002345970.1 218928095 1173759 complement(1012248..1013264) 1 NC_003143.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 1013264 epd 1173759 epd Yersinia pestis CO92 erythrose 4-phosphate dehydrogenase YP_002345970.1 1012248 R 214092 CDS YP_002345971.1 218928096 1173760 complement(1013579..1014361) 1 NC_003143.1 transposase/IS protein 1014361 1173760 YPO0923 Yersinia pestis CO92 transposase/IS protein YP_002345971.1 1013579 R 214092 CDS YP_002345972.1 218928097 1173761 complement(1014358..1015380) 1 NC_003143.1 transposase for insertion sequence IS100 1015380 y1093 1173761 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002345972.1 1014358 R 214092 CDS YP_002345973.1 218928098 1173762 complement(1015564..1016022) 1 NC_003143.1 transposase for the IS1541 insertion element 1016022 tnp 1173762 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002345973.1 1015564 R 214092 CDS YP_002345974.1 218928099 1173763 complement(1016330..1018324) 1 NC_003143.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1018324 tktA 1173763 tktA Yersinia pestis CO92 transketolase YP_002345974.1 1016330 R 214092 CDS YP_002345975.1 218928100 1173764 1018815..1019567 1 NC_003143.1 lipoprotein 1019567 1173764 YPO0927 Yersinia pestis CO92 lipoprotein YP_002345975.1 1018815 D 214092 CDS YP_002345976.1 218928101 1173765 complement(1019857..1020177) 1 NC_003143.1 Rieske protein 1020177 1173765 YPO0928 Yersinia pestis CO92 Rieske protein YP_002345976.1 1019857 R 214092 CDS YP_002345977.1 218928102 1173766 complement(1020337..1022316) 1 NC_003143.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 1022316 speA 1173766 speA Yersinia pestis CO92 arginine decarboxylase YP_002345977.1 1020337 R 214092 CDS YP_002345978.1 218928103 1173767 1023523..1024677 1 NC_003143.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1024677 metK 1173767 metK Yersinia pestis CO92 S-adenosylmethionine synthetase YP_002345978.1 1023523 D 214092 CDS YP_002345979.1 218928104 1173768 1024870..1025382 1 NC_003143.1 hypothetical protein 1025382 1173768 YPO0932 Yersinia pestis CO92 hypothetical protein YP_002345979.1 1024870 D 214092 CDS YP_002345980.1 218928105 1173769 1025480..1026187 1 NC_003143.1 endonuclease I 1026187 endA 1173769 endA Yersinia pestis CO92 endonuclease I YP_002345980.1 1025480 D 214092 CDS YP_002345981.1 218928106 1173770 1026439..1027170 1 NC_003143.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1027170 1173770 YPO0934 Yersinia pestis CO92 16S ribosomal RNA methyltransferase RsmE YP_002345981.1 1026439 D 214092 CDS YP_002345982.1 218928107 1173771 1027196..1028155 1 NC_003143.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 1028155 gshB 1173771 gshB Yersinia pestis CO92 glutathione synthetase YP_002345982.1 1027196 D 214092 CDS YP_002345983.1 218928108 1173772 1028271..1028834 1 NC_003143.1 hypothetical protein 1028834 1173772 YPO0936 Yersinia pestis CO92 hypothetical protein YP_002345983.1 1028271 D 214092 CDS YP_002345984.1 218928109 1173773 1028834..1029256 1 NC_003143.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 1029256 1173773 YPO0937 Yersinia pestis CO92 Holliday junction resolvase-like protein YP_002345984.1 1028834 D 214092 CDS YP_002345985.1 218928110 1173774 1029436..1030320 1 NC_003143.1 carbon-nitrogen hydrolase 1030320 1173774 YPO0938 Yersinia pestis CO92 carbon-nitrogen hydrolase YP_002345985.1 1029436 D 214092 CDS YP_002345986.1 218928111 1173775 1030324..1031439 1 NC_003143.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis; agmatine deiminase 1031439 1173775 YPO0939 Yersinia pestis CO92 agmatine deiminase YP_002345986.1 1030324 D 214092 CDS YP_002345987.1 218928112 1173776 complement(1031548..1032624) 1 NC_003143.1 hypothetical protein 1032624 1173776 YPO0940 Yersinia pestis CO92 hypothetical protein YP_002345987.1 1031548 R 214092 CDS YP_002345988.1 218928113 1173777 1032692..1033390 1 NC_003143.1 hypothetical protein 1033390 1173777 YPO0941 Yersinia pestis CO92 hypothetical protein YP_002345988.1 1032692 D 214092 CDS YP_002345989.1 218928114 1173778 1033523..1034344 1 NC_003143.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 1034344 proC 1173778 proC Yersinia pestis CO92 pyrroline-5-carboxylate reductase YP_002345989.1 1033523 D 214092 CDS YP_002345990.1 218928115 1173779 1034632..1035186 1 NC_003143.1 hypothetical protein 1035186 yggT 1173779 yggT Yersinia pestis CO92 hypothetical protein YP_002345990.1 1034632 D 214092 CDS YP_002345991.1 218928116 1173780 1035183..1035473 1 NC_003143.1 hypothetical protein 1035473 1173780 YPO0944 Yersinia pestis CO92 hypothetical protein YP_002345991.1 1035183 D 214092 CDS YP_002345992.1 218928117 1173781 1035573..1036166 1 NC_003143.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 1036166 1173781 YPO0945 Yersinia pestis CO92 deoxyribonucleotide triphosphate pyrophosphatase YP_002345992.1 1035573 D 214092 CDS YP_002345993.1 218928118 1173782 1036159..1037289 1 NC_003143.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1037289 1173782 YPO0946 Yersinia pestis CO92 coproporphyrinogen III oxidase YP_002345993.1 1036159 D 214092 CDS YP_002345994.1 218928119 1173783 complement(1037479..1046811) 1 NC_003143.1 virulence determinant 1046811 1173783 YPO0947 Yersinia pestis CO92 virulence determinant YP_002345994.1 1037479 R 214092 CDS YP_002345995.1 218928120 1173785 complement(1048155..1049081) 1 NC_003143.1 catalyzes the formation of glutamate from glutamine; glutaminase 1049081 1173785 YPO0949 Yersinia pestis CO92 glutaminase YP_002345995.1 1048155 R 214092 CDS YP_002345996.1 218928121 1173786 complement(1049192..1049518) 1 NC_003143.1 hypothetical protein 1049518 1173786 YPO0950 Yersinia pestis CO92 hypothetical protein YP_002345996.1 1049192 R 214092 CDS YP_002345997.1 218928122 1173787 complement(1049518..1050237) 1 NC_003143.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1050237 trmB 1173787 trmB Yersinia pestis CO92 tRNA (guanine-N(7)-)-methyltransferase YP_002345997.1 1049518 R 214092 CDS YP_002345998.1 218928123 1173788 1050575..1051690 1 NC_003143.1 adenine DNA glycosylase 1051690 mutY 1173788 mutY Yersinia pestis CO92 adenine DNA glycosylase YP_002345998.1 1050575 D 214092 CDS YP_002345999.1 218928124 1173789 1051868..1052140 1 NC_003143.1 hypothetical protein 1052140 1173789 YPO0953 Yersinia pestis CO92 hypothetical protein YP_002345999.1 1051868 D 214092 CDS YP_002346000.1 218928125 1173790 1052323..1053399 1 NC_003143.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 1053399 mltC 1173790 mltC Yersinia pestis CO92 murein transglycosylase C YP_002346000.1 1052323 D 214092 CDS YP_002346001.2 284987067 1173791 1053699..1054799 1 NC_003143.1 hypothetical protein 1054799 1173791 YPO0955 Yersinia pestis CO92 hypothetical protein YP_002346001.2 1053699 D 214092 CDS YP_002346002.1 218928127 1173792 1054837..1056936 1 NC_003143.1 hydroxamate-type ferrisiderophore receptor 1056936 1173792 YPO0956 Yersinia pestis CO92 hydroxamate-type ferrisiderophore receptor YP_002346002.1 1054837 D 214092 CDS YP_002346003.1 218928128 1173793 complement(1057019..1058038) 1 NC_003143.1 sugar transport system permease 1058038 1173793 YPO0957 Yersinia pestis CO92 sugar transport system permease YP_002346003.1 1057019 R 214092 CDS YP_002346004.1 218928129 1173794 complement(1058035..1059534) 1 NC_003143.1 sugar transport ATP-binding protein 1059534 mglA 1173794 mglA Yersinia pestis CO92 sugar transport ATP-binding protein YP_002346004.1 1058035 R 214092 CDS YP_002346005.1 218928130 1173795 complement(1059580..1060539) 1 NC_003143.1 sugar ABC transporter substrate-binding protein 1060539 1173795 YPO0959 Yersinia pestis CO92 sugar ABC transporter substrate-binding protein YP_002346005.1 1059580 R 214092 CDS YP_002346006.1 218928131 1173796 complement(1061095..1063257) 1 NC_003143.1 ornithine decarboxylase 1063257 speC 1173796 speC Yersinia pestis CO92 ornithine decarboxylase YP_002346006.1 1061095 R 214092 CDS YP_002346009.1 218928134 1173800 complement(1065829..1066185) 1 NC_003143.1 insertion sequence protein 1066185 insB 1173800 insB Yersinia pestis CO92 insertion sequence protein YP_002346009.1 1065829 R 214092 CDS YP_002346010.1 218928135 1173801 complement(1066251..1066526) 1 NC_003143.1 insertion sequence protein 1066526 insA 1173801 insA Yersinia pestis CO92 insertion sequence protein YP_002346010.1 1066251 R 214092 CDS YP_002346011.1 218928136 1173802 complement(1066622..1067371) 1 NC_003143.1 no significant database hits; hypothetical protein 1067371 1173802 YPO0965 Yersinia pestis CO92 hypothetical protein YP_002346011.1 1066622 R 214092 CDS YP_002346012.1 218928137 1173803 complement(1067376..1069673) 1 NC_003143.1 kinase 1069673 1173803 YPO0966 Yersinia pestis CO92 kinase YP_002346012.1 1067376 R 214092 CDS YP_002346015.1 218928140 1173806 complement(1071245..1071520) 1 NC_003143.1 insertion sequence protein 1071520 insA 1173806 insA Yersinia pestis CO92 insertion sequence protein YP_002346015.1 1071245 R 214092 CDS YP_002346017.1 218928142 1173808 complement(1072398..1074620) 1 NC_003143.1 no significant database hits; hypothetical protein 1074620 1173808 YPO0969 Yersinia pestis CO92 hypothetical protein YP_002346017.1 1072398 R 214092 CDS YP_002346018.1 218928143 1173809 complement(1074635..1076983) 1 NC_003143.1 hypothetical protein 1076983 1173809 YPO0970 Yersinia pestis CO92 hypothetical protein YP_002346018.1 1074635 R 214092 CDS YP_002346019.1 218928144 1173810 complement(1076980..1079628) 1 NC_003143.1 Clp ATPase 1079628 clpB3 1173810 clpB3 Yersinia pestis CO92 Clp ATPase YP_002346019.1 1076980 R 214092 CDS YP_002346020.1 218928145 1173811 complement(1080046..1080537) 1 NC_003143.1 hypothetical protein 1080537 1173811 YPO0973 Yersinia pestis CO92 hypothetical protein YP_002346020.1 1080046 R 214092 CDS YP_002346021.1 218928146 1173812 complement(1080541..1082277) 1 NC_003143.1 OmpA family membrane protein 1082277 1173812 YPO0974 Yersinia pestis CO92 OmpA family membrane protein YP_002346021.1 1080541 R 214092 CDS YP_002346022.1 218928147 1173813 complement(1082277..1082963) 1 NC_003143.1 hypothetical protein 1082963 1173813 YPO0975 Yersinia pestis CO92 hypothetical protein YP_002346022.1 1082277 R 214092 CDS YP_002346023.1 218928148 1173814 complement(1082960..1084312) 1 NC_003143.1 hypothetical protein 1084312 1173814 YPO0976 Yersinia pestis CO92 hypothetical protein YP_002346023.1 1082960 R 214092 CDS YP_002346024.1 218928149 1173815 complement(1084324..1085868) 1 NC_003143.1 hypothetical protein 1085868 1173815 YPO0977 Yersinia pestis CO92 hypothetical protein YP_002346024.1 1084324 R 214092 CDS YP_002346025.1 218928150 1173816 complement(1085911..1086411) 1 NC_003143.1 hypothetical protein 1086411 1173816 YPO0978 Yersinia pestis CO92 hypothetical protein YP_002346025.1 1085911 R 214092 CDS YP_008853945.1 559797720 17699569 complement(1087811..1088182) 1 NC_003143.1 hypothetical protein 1088182 17699569 YPO0978a Yersinia pestis CO92 hypothetical protein YP_008853945.1 1087811 R 214092 CDS YP_002346028.1 218928153 1173820 complement(1088356..1088619) 1 NC_003143.1 insertion element protein 1088619 insA 1173820 insA Yersinia pestis CO92 insertion element protein YP_002346028.1 1088356 R 214092 CDS YP_002346029.1 218928154 1173821 complement(1088687..1089082) 1 NC_003143.1 lipoprotein 1089082 1173821 YPO0982 Yersinia pestis CO92 lipoprotein YP_002346029.1 1088687 R 214092 CDS YP_002346030.1 218928155 1173822 complement(1089533..1090183) 1 NC_003143.1 hypothetical protein 1090183 1173822 YPO0983 Yersinia pestis CO92 hypothetical protein YP_002346030.1 1089533 R 214092 CDS YP_002346031.1 218928156 1173823 1091363..1092013 1 NC_003143.1 N-acylhomoserine lactone synthase 1092013 yspI 1173823 yspI Yersinia pestis CO92 N-acylhomoserine lactone synthase YP_002346031.1 1091363 D 214092 CDS YP_002346032.1 218928157 1173824 complement(1091994..1092737) 1 NC_003143.1 quorum-sensing transcriptional regulator 1092737 yspR 1173824 yspR Yersinia pestis CO92 quorum-sensing transcriptional regulator YP_002346032.1 1091994 R 214092 CDS YP_002346033.1 218928158 1173825 1093299..1094675 1 NC_003143.1 hypothetical protein 1094675 1173825 YPO0986 Yersinia pestis CO92 hypothetical protein YP_002346033.1 1093299 D 214092 CDS YP_002346034.1 218928159 1173826 1095052..1095885 1 NC_003143.1 hypothetical protein 1095885 1173826 YPO0987 Yersinia pestis CO92 hypothetical protein YP_002346034.1 1095052 D 214092 CDS YP_002346035.1 218928160 1173827 complement(1096175..1097398) 1 NC_003143.1 hypothetical protein 1097398 1173827 YPO0988 Yersinia pestis CO92 hypothetical protein YP_002346035.1 1096175 R 214092 CDS YP_002346036.1 218928161 1173829 1099293..1100243 1 NC_003143.1 siderophore biosynthesis protein IucB 1100243 iucB 1173829 iucB Yersinia pestis CO92 siderophore biosynthesis protein IucB YP_002346036.1 1099293 D 214092 CDS YP_002346037.1 218928162 1173830 1100240..1101988 1 NC_003143.1 siderophore biosynthesis protein IucC 1101988 iucC 1173830 iucC Yersinia pestis CO92 siderophore biosynthesis protein IucC YP_002346037.1 1100240 D 214092 CDS YP_002346038.1 218928163 1173831 1101985..1103313 1 NC_003143.1 siderophore biosynthesis protein IucD 1103313 iucD 1173831 iucD Yersinia pestis CO92 siderophore biosynthesis protein IucD YP_002346038.1 1101985 D 214092 CDS YP_002346039.1 218928164 1173832 1103385..1105565 1 NC_003143.1 ferric siderophore receptor 1105565 iutA 1173832 iutA Yersinia pestis CO92 ferric siderophore receptor YP_002346039.1 1103385 D 214092 CDS YP_002346040.1 218928165 1173833 complement(1105824..1107257) 1 NC_003143.1 sodium:galactoside symporter family protein 1107257 1173833 YPO0995 Yersinia pestis CO92 sodium:galactoside symporter family protein YP_002346040.1 1105824 R 214092 CDS YP_002346041.2 537470145 1173834 1107355..1108035 1 NC_003143.1 insertion element IS1661 DNA-binding protein 1108035 1173834 YPO0996 Yersinia pestis CO92 insertion element IS1661 DNA-binding protein YP_002346041.2 1107355 D 214092 CDS YP_002346042.1 218928167 1173835 1108089..1108874 1 NC_003143.1 transposase for insertion sequence IS1661 1108874 1173835 YPO0997 Yersinia pestis CO92 transposase for insertion sequence IS1661 YP_002346042.1 1108089 D 214092 CDS YP_002346043.1 218928168 1173836 complement(1109070..1111436) 1 NC_003143.1 hypothetical protein 1111436 1173836 YPO0998 Yersinia pestis CO92 hypothetical protein YP_002346043.1 1109070 R 214092 CDS YP_002346044.1 218928169 1173837 complement(1111440..1111637) 1 NC_003143.1 hypothetical protein 1111637 1173837 YPO0999 Yersinia pestis CO92 hypothetical protein YP_002346044.1 1111440 R 214092 CDS YP_002346045.1 218928170 1173838 1112076..1113353 1 NC_003143.1 drug efflux protein 1113353 1173838 YPO1000 Yersinia pestis CO92 drug efflux protein YP_002346045.1 1112076 D 214092 CDS YP_002346046.1 218928171 1173839 1113366..1116485 1 NC_003143.1 integral membrane efflux protein 1116485 1173839 YPO1001 Yersinia pestis CO92 integral membrane efflux protein YP_002346046.1 1113366 D 214092 CDS YP_002346047.1 218928172 1173840 complement(1116620..1118110) 1 NC_003143.1 enterotoxin-like protein 1118110 1173840 YPO1002 Yersinia pestis CO92 enterotoxin-like protein YP_002346047.1 1116620 R 214092 CDS YP_002346048.1 218928173 1173841 1118388..1118975 1 NC_003143.1 hypothetical protein 1118975 1173841 YPO1003 Yersinia pestis CO92 hypothetical protein YP_002346048.1 1118388 D 214092 CDS YP_002346049.1 218928174 1173842 1119829..1130946 1 NC_003143.1 autotransporter protein 1130946 yapH 1173842 yapH Yersinia pestis CO92 autotransporter protein YP_002346049.1 1119829 D 214092 CDS YP_002346050.1 218928175 1173843 complement(1131049..1132929) 1 NC_003143.1 hypothetical protein 1132929 1173843 YPO1005 Yersinia pestis CO92 hypothetical protein YP_002346050.1 1131049 R 214092 CDS YP_002346051.1 218928176 1173844 complement(1133492..1134367) 1 NC_003143.1 hypothetical protein 1134367 1173844 YPO1006 Yersinia pestis CO92 hypothetical protein YP_002346051.1 1133492 R 214092 CDS YP_002346052.1 218928177 1173845 complement(1134575..1136392) 1 NC_003143.1 hypothetical protein 1136392 1173845 YPO1007 Yersinia pestis CO92 hypothetical protein YP_002346052.1 1134575 R 214092 CDS YP_002346053.1 218928178 1173846 1137111..1138667 1 NC_003143.1 integral membrane efflux protein 1138667 1173846 YPO1008 Yersinia pestis CO92 integral membrane efflux protein YP_002346053.1 1137111 D 214092 CDS YP_002346054.1 218928179 1173847 1138745..1139977 1 NC_003143.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1139977 1173847 YPO1009 Yersinia pestis CO92 peptidase T YP_002346054.1 1138745 D 214092 CDS YP_002346055.1 218928180 1173848 1140365..1142437 1 NC_003143.1 TonB-dependent outer membrane receptor 1142437 1173848 YPO1011 Yersinia pestis CO92 TonB-dependent outer membrane receptor YP_002346055.1 1140365 D 214092 CDS YP_008479687.1 537470146 1173849 1142588..1146001 1 NC_003143.1 nonribosomal peptide synthetase/polyketide synthase 1146001 1173849 YPO1012 Yersinia pestis CO92 nonribosomal peptide synthetase/polyketide synthase YP_008479687.1 1142588 D 214092 CDS YP_002346056.1 218928181 1173850 1146015..1147037 1 NC_003143.1 transposase for insertion sequence IS100 1147037 y1093 1173850 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346056.1 1146015 D 214092 CDS YP_002346057.1 218928182 1173851 1147034..1147816 1 NC_003143.1 transposase/IS protein 1147816 1173851 YPO1014 Yersinia pestis CO92 transposase/IS protein YP_002346057.1 1147034 D 214092 CDS YP_002346059.1 218928184 1173853 1148051..1148659 1 NC_003143.1 hypothetical protein 1148659 1173853 YPO1015 Yersinia pestis CO92 hypothetical protein YP_002346059.1 1148051 D 214092 CDS YP_002346060.1 218928185 1173854 1148656..1149126 1 NC_003143.1 hypothetical protein 1149126 1173854 YPO1016 Yersinia pestis CO92 hypothetical protein YP_002346060.1 1148656 D 214092 CDS YP_002346061.1 218928186 1173855 1149114..1149524 1 NC_003143.1 prepilin peptidase dependent protein 1149524 1173855 YPO1017 Yersinia pestis CO92 prepilin peptidase dependent protein YP_002346061.1 1149114 D 214092 CDS YP_002346062.1 218928187 1173856 1149659..1153030 1 NC_003143.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 1153030 recC 1173856 recC Yersinia pestis CO92 exonuclease V subunit gamma YP_002346062.1 1149659 D 214092 CDS YP_002346063.1 218928188 1173857 1153112..1156000 1 NC_003143.1 protease III 1156000 ptr 1173857 ptr Yersinia pestis CO92 protease III YP_002346063.1 1153112 D 214092 CDS YP_002346064.1 218928189 1173858 1155997..1159659 1 NC_003143.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 1159659 recB 1173858 recB Yersinia pestis CO92 exonuclease V subunit beta YP_002346064.1 1155997 D 214092 CDS YP_002346065.1 218928190 1173859 1159656..1161614 1 NC_003143.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 1161614 recD 1173859 recD Yersinia pestis CO92 exonuclease V subunit alpha YP_002346065.1 1159656 D 214092 CDS YP_002346066.1 218928191 1173860 complement(1161769..1163094) 1 NC_003143.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 1163094 argA 1173860 argA Yersinia pestis CO92 N-acetylglutamate synthase YP_002346066.1 1161769 R 214092 CDS YP_002346067.1 218928192 1173861 1163330..1164580 1 NC_003143.1 N-acetylmuramoyl-L-alanine amidase 1164580 1173861 YPO1023 Yersinia pestis CO92 N-acetylmuramoyl-L-alanine amidase YP_002346067.1 1163330 D 214092 CDS YP_002346068.1 218928193 1173864 1165302..1166474 1 NC_003143.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 1166474 mltA 1173864 mltA Yersinia pestis CO92 murein transglycosylase A YP_002346068.1 1165302 D 214092 CDS YP_002346069.1 218928194 1173865 1166617..1167444 1 NC_003143.1 hypothetical protein 1167444 1173865 YPO1026 Yersinia pestis CO92 hypothetical protein YP_002346069.1 1166617 D 214092 CDS YP_002346070.1 218928195 1173866 complement(1167480..1167923) 1 NC_003143.1 hypothetical protein 1167923 1173866 YPO1027 Yersinia pestis CO92 hypothetical protein YP_002346070.1 1167480 R 214092 CDS YP_002346071.1 218928196 1173867 complement(1168058..1169377) 1 NC_003143.1 cysteine sulfinate desulfinase 1169377 1173867 YPO1028 Yersinia pestis CO92 cysteine sulfinate desulfinase YP_002346071.1 1168058 R 214092 CDS YP_002346072.1 218928197 1173868 1169923..1170840 1 NC_003143.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 1170840 gcvA 1173868 gcvA Yersinia pestis CO92 DNA-binding transcriptional activator GcvA YP_002346072.1 1169923 D 214092 CDS YP_002346073.1 218928198 1173869 1171006..1171401 1 NC_003143.1 hypothetical protein 1171401 1173869 YPO1030 Yersinia pestis CO92 hypothetical protein YP_002346073.1 1171006 D 214092 CDS YP_002346074.1 218928199 1173870 1171394..1172500 1 NC_003143.1 RNA 2'-O-ribose methyltransferase 1172500 1173870 YPO1031 Yersinia pestis CO92 RNA 2'-O-ribose methyltransferase YP_002346074.1 1171394 D 214092 CDS YP_002346075.1 218928200 1173871 complement(1172751..1173506) 1 NC_003143.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 1173506 xni 1173871 xni Yersinia pestis CO92 exonuclease IX YP_002346075.1 1172751 R 214092 CDS YP_002346076.1 218928201 1173872 complement(1173766..1175130) 1 NC_003143.1 hypothetical protein 1175130 1173872 YPO1033 Yersinia pestis CO92 hypothetical protein YP_002346076.1 1173766 R 214092 CDS YP_002346077.1 218928202 1173873 complement(1175283..1176128) 1 NC_003143.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1176128 queF 1173873 queF Yersinia pestis CO92 7-cyano-7-deazaguanine reductase YP_002346077.1 1175283 R 214092 CDS YP_002346078.1 218928203 1173874 1176266..1176811 1 NC_003143.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 1176811 syd 1173874 syd Yersinia pestis CO92 SecY interacting protein Syd YP_002346078.1 1176266 D 214092 CDS YP_002346079.1 218928204 1173876 1177501..1177959 1 NC_003143.1 transposase for the IS1541 insertion element 1177959 tnp 1173876 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346079.1 1177501 D 214092 CDS YP_002346080.1 218928205 1173877 1178213..1178545 1 NC_003143.1 hypothetical protein 1178545 1173877 YPO1037 Yersinia pestis CO92 hypothetical protein YP_002346080.1 1178213 D 214092 CDS YP_002346081.1 218928206 1173878 1178545..1179318 1 NC_003143.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 1179318 1173878 YPO1038 Yersinia pestis CO92 tRNA pseudouridine synthase C YP_002346081.1 1178545 D 214092 CDS YP_002346082.1 218928207 1173879 1179346..1179795 1 NC_003143.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1179795 1173879 YPO1039 Yersinia pestis CO92 flavodoxin YP_002346082.1 1179346 D 214092 CDS YP_002346083.1 218928208 1173880 complement(1179885..1180274) 1 NC_003143.1 hypothetical protein 1180274 1173880 YPO1040 Yersinia pestis CO92 hypothetical protein YP_002346083.1 1179885 R 214092 CDS YP_002346084.1 218928209 1173881 complement(1180398..1181222) 1 NC_003143.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1181222 dapD 1173881 dapD Yersinia pestis CO92 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_002346084.1 1180398 R 214092 CDS YP_002346085.1 218928210 1173882 complement(1181397..1184135) 1 NC_003143.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 1184135 glnD 1173882 glnD Yersinia pestis CO92 PII uridylyl-transferase YP_002346085.1 1181397 R 214092 CDS YP_002346086.1 218928211 1173883 complement(1184138..1184929) 1 NC_003143.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1184929 ampM 1173883 ampM Yersinia pestis CO92 methionine aminopeptidase YP_002346086.1 1184138 R 214092 CDS YP_002346087.1 218928212 1173884 1185364..1186089 1 NC_003143.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1186089 rpsB 1173884 rpsB Yersinia pestis CO92 30S ribosomal protein S2 YP_002346087.1 1185364 D 214092 CDS YP_002346088.1 218928213 1173885 1186217..1187074 1 NC_003143.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1187074 tsf 1173885 tsf Yersinia pestis CO92 elongation factor Ts YP_002346088.1 1186217 D 214092 CDS YP_002346089.1 218928214 1173886 1187283..1188008 1 NC_003143.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1188008 pyrH 1173886 pyrH Yersinia pestis CO92 uridylate kinase YP_002346089.1 1187283 D 214092 CDS YP_002346090.1 218928215 1173887 1188144..1188701 1 NC_003143.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1188701 frr 1173887 frr Yersinia pestis CO92 ribosome recycling factor YP_002346090.1 1188144 D 214092 CDS YP_002346091.1 218928216 1173888 1188915..1190111 1 NC_003143.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1190111 dxr 1173888 dxr Yersinia pestis CO92 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002346091.1 1188915 D 214092 CDS YP_002346092.1 218928217 1173889 1190335..1191093 1 NC_003143.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 1191093 rth 1173889 rth Yersinia pestis CO92 undecaprenyl pyrophosphate synthase YP_002346092.1 1190335 D 214092 CDS YP_002346093.1 218928218 1173890 1191103..1191951 1 NC_003143.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 1191951 cdsA 1173890 cdsA Yersinia pestis CO92 CDP-diglyceride synthase YP_002346093.1 1191103 D 214092 CDS YP_002346094.1 218928219 1173891 1191980..1193335 1 NC_003143.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 1193335 1173891 YPO1051 Yersinia pestis CO92 zinc metallopeptidase RseP YP_002346094.1 1191980 D 214092 CDS YP_002346095.1 218928220 1173892 1193372..1195759 1 NC_003143.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 1195759 1173892 YPO1052 Yersinia pestis CO92 outer membrane protein assembly factor YaeT YP_002346095.1 1193372 D 214092 CDS YP_002346096.1 218928221 1173893 1195917..1196414 1 NC_003143.1 periplasmic chaperone 1196414 ompH 1173893 ompH Yersinia pestis CO92 periplasmic chaperone YP_002346096.1 1195917 D 214092 CDS YP_002346097.1 218928222 1173894 1196418..1197440 1 NC_003143.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1197440 lpxD 1173894 lpxD Yersinia pestis CO92 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_002346097.1 1196418 D 214092 CDS YP_002346098.1 218928223 1173895 1197598..1198143 1 NC_003143.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1198143 fabZ 1173895 fabZ Yersinia pestis CO92 (3R)-hydroxymyristoyl-ACP dehydratase YP_002346098.1 1197598 D 214092 CDS YP_002346099.1 218928224 1173896 1198147..1198935 1 NC_003143.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 1198935 lpxA 1173896 lpxA Yersinia pestis CO92 UDP-N-acetylglucosamine acyltransferase YP_002346099.1 1198147 D 214092 CDS YP_002346100.1 218928225 1173897 1198939..1200123 1 NC_003143.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 1200123 lpxB 1173897 lpxB Yersinia pestis CO92 lipid-A-disaccharide synthase YP_002346100.1 1198939 D 214092 CDS YP_002346101.1 218928226 1173898 1200120..1200716 1 NC_003143.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1200716 rnhB 1173898 rnhB Yersinia pestis CO92 ribonuclease HII YP_002346101.1 1200120 D 214092 CDS YP_002346102.1 218928227 1173899 1200846..1204361 1 NC_003143.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 1204361 dnaE 1173899 dnaE Yersinia pestis CO92 DNA polymerase III subunit alpha YP_002346102.1 1200846 D 214092 CDS YP_002346103.1 218928228 1173900 1204374..1205333 1 NC_003143.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1205333 accA 1173900 accA Yersinia pestis CO92 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_002346103.1 1204374 D 214092 CDS YP_002346104.1 218928229 1173901 1205517..1205915 1 NC_003143.1 hypothetical protein 1205915 1173901 YPO1061 Yersinia pestis CO92 hypothetical protein YP_002346104.1 1205517 D 214092 CDS YP_002346105.1 218928230 1173902 1205917..1207299 1 NC_003143.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 1207299 tilS 1173902 tilS Yersinia pestis CO92 tRNA(Ile)-lysidine synthetase YP_002346105.1 1205917 D 214092 CDS YP_002346106.1 218928231 1173903 1207536..1207853 1 NC_003143.1 cytochrome 1207853 1173903 YPO1063 Yersinia pestis CO92 cytochrome YP_002346106.1 1207536 D 214092 CDS YP_002346107.1 218928232 1173904 complement(1208118..1208378) 1 NC_003143.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 1208378 1173904 YPO1064 Yersinia pestis CO92 Rho-binding antiterminator YP_002346107.1 1208118 R 214092 CDS YP_002346108.1 218928233 1173905 complement(1208365..1208565) 1 NC_003143.1 hypothetical protein 1208565 1173905 YPO1064a Yersinia pestis CO92 hypothetical protein YP_002346108.1 1208365 R 214092 CDS YP_002346109.1 218928234 1173906 1208807..1209355 1 NC_003143.1 hypothetical protein 1209355 1173906 YPO1065 Yersinia pestis CO92 hypothetical protein YP_002346109.1 1208807 D 214092 CDS YP_002346110.1 218928235 1173907 1209358..1209774 1 NC_003143.1 peptidyl-tRNA hydrolase domain-containing protein 1209774 1173907 YPO1066 Yersinia pestis CO92 peptidyl-tRNA hydrolase domain-containing protein YP_002346110.1 1209358 D 214092 CDS YP_002346111.1 218928236 1173908 1209814..1210542 1 NC_003143.1 lipoprotein involved with copper homeostasis and adhesion 1210542 cutF 1173908 cutF Yersinia pestis CO92 lipoprotein involved with copper homeostasis and adhesion YP_002346111.1 1209814 D 214092 CDS YP_002346112.1 218928237 1173909 complement(1210676..1212394) 1 NC_003143.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1212394 proS 1173909 proS Yersinia pestis CO92 prolyl-tRNA synthetase YP_002346112.1 1210676 R 214092 CDS YP_002346113.1 218928238 1173910 complement(1212498..1213205) 1 NC_003143.1 hypothetical protein 1213205 1173910 YPO1069 Yersinia pestis CO92 hypothetical protein YP_002346113.1 1212498 R 214092 CDS YP_002346114.1 218928239 1173911 complement(1213202..1213609) 1 NC_003143.1 outer membrane lipoprotein 1213609 rcsF 1173911 rcsF Yersinia pestis CO92 outer membrane lipoprotein YP_002346114.1 1213202 R 214092 CDS YP_002346115.1 218928240 1173912 complement(1213727..1214542) 1 NC_003143.1 DL-methionine transporter substrate-binding subunit 1214542 metQ 1173912 metQ Yersinia pestis CO92 DL-methionine transporter substrate-binding subunit YP_002346115.1 1213727 R 214092 CDS YP_002346116.1 218928241 1173913 complement(1214606..1215259) 1 NC_003143.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease 1215259 1173913 YPO1072 Yersinia pestis CO92 DL-methionine transporter permease YP_002346116.1 1214606 R 214092 CDS YP_002346117.1 218928242 1173914 complement(1215252..1216283) 1 NC_003143.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding protein 1216283 metN 1173914 metN Yersinia pestis CO92 DL-methionine transporter ATP-binding protein YP_002346117.1 1215252 R 214092 CDS YP_002346118.1 218928243 1173915 1216470..1217036 1 NC_003143.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 1217036 1173915 YPO1074 Yersinia pestis CO92 D,D-heptose 1,7-bisphosphate phosphatase YP_002346118.1 1216470 D 214092 CDS YP_008479688.1 537470147 16744743 complement(1217287..1217472) 1 NC_003143.1 hypothetical protein 1217472 16744743 YPO1074a Yersinia pestis CO92 hypothetical protein YP_008479688.1 1217287 R 214092 CDS YP_002346119.1 218928244 1173921 1223177..1223980 1 NC_003143.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 1223980 dkgB 1173921 dkgB Yersinia pestis CO92 2,5-diketo-D-gluconate reductase B YP_002346119.1 1223177 D 214092 CDS YP_002346120.1 218928245 1173922 1224015..1224479 1 NC_003143.1 no significant database hits; hypothetical protein 1224479 1173922 YPO1076 Yersinia pestis CO92 hypothetical protein YP_002346120.1 1224015 D 214092 CDS YP_002346121.1 218928246 1173923 1224840..1225622 1 NC_003143.1 hypothetical protein 1225622 1173923 YPO1077 Yersinia pestis CO92 hypothetical protein YP_002346121.1 1224840 D 214092 CDS YP_002346122.1 218928247 1173924 complement(1225664..1227091) 1 NC_003143.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 1227091 mltD 1173924 mltD Yersinia pestis CO92 membrane-bound lytic murein transglycosylase D YP_002346122.1 1225664 R 214092 CDS YP_002346123.1 218928248 1173925 complement(1227124..1227879) 1 NC_003143.1 hydroxyacylglutathione hydrolase 1227879 gloB 1173925 gloB Yersinia pestis CO92 hydroxyacylglutathione hydrolase YP_002346123.1 1227124 R 214092 CDS YP_002346124.1 218928249 1173926 1227924..1228643 1 NC_003143.1 hypothetical protein 1228643 1173926 YPO1080 Yersinia pestis CO92 hypothetical protein YP_002346124.1 1227924 D 214092 CDS YP_002346125.1 218928250 1173927 complement(1228698..1229162) 1 NC_003143.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 1229162 rnhA 1173927 rnhA Yersinia pestis CO92 ribonuclease H YP_002346125.1 1228698 R 214092 CDS YP_002346126.1 218928251 1173928 1229232..1229996 1 NC_003143.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1229996 dnaQ 1173928 dnaQ Yersinia pestis CO92 DNA polymerase III subunit epsilon YP_002346126.1 1229232 D 214092 CDS YP_002346127.1 218928252 1173930 complement(1230242..1231726) 1 NC_003143.1 permease 1231726 1173930 YPO1083 Yersinia pestis CO92 permease YP_002346127.1 1230242 R 214092 CDS YP_002346128.1 218928253 1173932 complement(1232349..1233131) 1 NC_003143.1 transposase/IS protein 1233131 1173932 YPO1085 Yersinia pestis CO92 transposase/IS protein YP_002346128.1 1232349 R 214092 CDS YP_002346129.1 218928254 1173933 complement(1233128..1234150) 1 NC_003143.1 transposase for insertion sequence IS100 1234150 y1093 1173933 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346129.1 1233128 R 214092 CDS YP_002346132.1 218928257 1173936 1235071..1235391 1 NC_003143.1 DNA-binding prophage protein 1235391 1173936 YPO1088 Yersinia pestis CO92 DNA-binding prophage protein YP_002346132.1 1235071 D 214092 CDS YP_002346133.1 218928258 1173937 complement(1235740..1236828) 1 NC_003143.1 regulatory prophage protein 1236828 1173937 YPO1089 Yersinia pestis CO92 regulatory prophage protein YP_002346133.1 1235740 R 214092 CDS YP_002346134.1 218928259 1173938 complement(1236825..1237784) 1 NC_003143.1 prophage DNA primase 1237784 1173938 YPO1090 Yersinia pestis CO92 prophage DNA primase YP_002346134.1 1236825 R 214092 CDS YP_002346135.1 218928260 1173939 complement(1237777..1238319) 1 NC_003143.1 prophage protein 1238319 1173939 YPO1091 Yersinia pestis CO92 prophage protein YP_002346135.1 1237777 R 214092 CDS YP_002346136.1 218928261 1173940 complement(1238512..1239408) 1 NC_003143.1 DNA-binding prophage protein 1239408 1173940 YPO1092 Yersinia pestis CO92 DNA-binding prophage protein YP_002346136.1 1238512 R 214092 CDS YP_002346140.1 218928265 1173944 complement(1240596..1242266) 1 NC_003143.1 hypothetical protein 1242266 1173944 YPO1096 Yersinia pestis CO92 hypothetical protein YP_002346140.1 1240596 R 214092 CDS YP_002346141.1 218928266 1173945 complement(1242317..1243405) 1 NC_003143.1 hypothetical protein 1243405 1173945 YPO1097 Yersinia pestis CO92 hypothetical protein YP_002346141.1 1242317 R 214092 CDS YP_002346142.1 218928267 1173946 complement(1243484..1244683) 1 NC_003143.1 prophage integrase 1244683 1173946 YPO1098 Yersinia pestis CO92 prophage integrase YP_002346142.1 1243484 R 214092 CDS YP_002346143.1 218928268 1173947 complement(1244907..1245365) 1 NC_003143.1 transposase for the IS1541 insertion element 1245365 tnp 1173947 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346143.1 1244907 R 214092 CDS YP_002346144.1 218928269 1173949 complement(1246000..1246482) 1 NC_003143.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1246482 smpB 1173949 smpB Yersinia pestis CO92 SsrA-binding protein YP_002346144.1 1246000 R 214092 CDS YP_002346145.1 218928270 1173950 1246643..1247077 1 NC_003143.1 hypothetical protein 1247077 1173950 YPO1102 Yersinia pestis CO92 hypothetical protein YP_002346145.1 1246643 D 214092 CDS YP_002346146.1 218928271 1173951 1247070..1247354 1 NC_003143.1 hypothetical protein 1247354 1173951 YPO1103 Yersinia pestis CO92 hypothetical protein YP_002346146.1 1247070 D 214092 CDS YP_002346147.1 218928272 1173952 complement(1247504..1247854) 1 NC_003143.1 hypothetical protein 1247854 1173952 YPO1104 Yersinia pestis CO92 hypothetical protein YP_002346147.1 1247504 R 214092 CDS YP_002346148.1 218928273 1173953 complement(1247959..1249638) 1 NC_003143.1 recombination and repair protein 1249638 1173953 YPO1105 Yersinia pestis CO92 recombination and repair protein YP_002346148.1 1247959 R 214092 CDS YP_002346149.1 218928274 1173954 complement(1249707..1250588) 1 NC_003143.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1250588 ppnK 1173954 ppnK Yersinia pestis CO92 inorganic polyphosphate/ATP-NAD kinase YP_002346149.1 1249707 R 214092 CDS YP_002346150.1 218928275 1173955 1250712..1251290 1 NC_003143.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1251290 1173955 YPO1107 Yersinia pestis CO92 heat shock protein GrpE YP_002346150.1 1250712 D 214092 CDS YP_002346151.1 218928276 1173956 complement(1251398..1252678) 1 NC_003143.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 1252678 gltA 1173956 gltA Yersinia pestis CO92 type II citrate synthase YP_002346151.1 1251398 R 214092 CDS YP_002346152.1 218928277 1173957 1253388..1253777 1 NC_003143.1 succinate dehydrogenase cytochrome b556 large membrane subunit 1253777 sdhC 1173957 sdhC Yersinia pestis CO92 succinate dehydrogenase cytochrome b556 large membrane subunit YP_002346152.1 1253388 D 214092 CDS YP_002346153.1 218928278 1173958 1253771..1254118 1 NC_003143.1 succinate dehydrogenase cytochrome b556 small membrane subunit 1254118 sdhD 1173958 sdhD Yersinia pestis CO92 succinate dehydrogenase cytochrome b556 small membrane subunit YP_002346153.1 1253771 D 214092 CDS YP_002346154.1 218928279 1173959 1254119..1255885 1 NC_003143.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 1255885 sdhA 1173959 sdhA Yersinia pestis CO92 succinate dehydrogenase flavoprotein subunit YP_002346154.1 1254119 D 214092 CDS YP_002346155.1 218928280 1173960 1255935..1256651 1 NC_003143.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 1256651 sdhB 1173960 sdhB Yersinia pestis CO92 succinate dehydrogenase iron-sulfur subunit YP_002346155.1 1255935 D 214092 CDS YP_002346156.1 218928281 1173961 1257007..1259814 1 NC_003143.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 1259814 sucA 1173961 sucA Yersinia pestis CO92 2-oxoglutarate dehydrogenase E1 YP_002346156.1 1257007 D 214092 CDS YP_002346157.1 218928282 1173962 1259844..1261067 1 NC_003143.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 1261067 sucB 1173962 sucB Yersinia pestis CO92 dihydrolipoamide succinyltransferase YP_002346157.1 1259844 D 214092 CDS YP_002346158.1 218928283 1173963 1261180..1262346 1 NC_003143.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1262346 sucC 1173963 sucC Yersinia pestis CO92 succinyl-CoA synthetase subunit beta YP_002346158.1 1261180 D 214092 CDS YP_002346159.1 218928284 1173964 1262346..1263218 1 NC_003143.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 1263218 sucD 1173964 sucD Yersinia pestis CO92 succinyl-CoA synthetase subunit alpha YP_002346159.1 1262346 D 214092 CDS YP_002346160.1 218928285 1173965 1263985..1265553 1 NC_003143.1 cytochrome D ubiquinol oxidase subunit I 1265553 cydA 1173965 cydA Yersinia pestis CO92 cytochrome D ubiquinol oxidase subunit I YP_002346160.1 1263985 D 214092 CDS YP_002346161.1 218928286 1173966 1265568..1266707 1 NC_003143.1 cytochrome D ubiquinol oxidase subunit II 1266707 cydB 1173966 cydB Yersinia pestis CO92 cytochrome D ubiquinol oxidase subunit II YP_002346161.1 1265568 D 214092 CDS YP_002346162.1 218928287 1173967 1266799..1267131 1 NC_003143.1 hypothetical protein 1267131 1173967 YPO1119 Yersinia pestis CO92 hypothetical protein YP_002346162.1 1266799 D 214092 CDS YP_002346163.1 218928288 1173968 1267263..1267664 1 NC_003143.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase 1267664 1173968 YPO1120 Yersinia pestis CO92 acyl-CoA thioester hydrolase YP_002346163.1 1267263 D 214092 CDS YP_002346164.1 218928289 1173969 1267664..1268350 1 NC_003143.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 1268350 tolQ 1173969 tolQ Yersinia pestis CO92 colicin uptake protein TolQ YP_002346164.1 1267664 D 214092 CDS YP_002346165.1 218928290 1173970 1268363..1268791 1 NC_003143.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 1268791 tolR 1173970 tolR Yersinia pestis CO92 colicin uptake protein TolR YP_002346165.1 1268363 D 214092 CDS YP_002346166.1 218928291 1173971 1268903..1270069 1 NC_003143.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins; cell envelope integrity inner membrane protein TolA 1270069 tolA 1173971 tolA Yersinia pestis CO92 cell envelope integrity inner membrane protein TolA YP_002346166.1 1268903 D 214092 CDS YP_002346167.1 218928292 1173972 1270189..1271481 1 NC_003143.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 1271481 tolB 1173972 tolB Yersinia pestis CO92 translocation protein TolB YP_002346167.1 1270189 D 214092 CDS YP_002346168.1 218928293 1173973 1271532..1272038 1 NC_003143.1 peptidoglycan-associated outer membrane lipoprotein 1272038 pal 1173973 pal Yersinia pestis CO92 peptidoglycan-associated outer membrane lipoprotein YP_002346168.1 1271532 D 214092 CDS YP_002346169.1 218928294 1173974 1272048..1272857 1 NC_003143.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 1272857 1173974 YPO1126 Yersinia pestis CO92 tol-pal system protein YbgF YP_002346169.1 1272048 D 214092 CDS YP_002346170.1 218928295 1173978 1273693..1274754 1 NC_003143.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1274754 nadA 1173978 nadA Yersinia pestis CO92 quinolinate synthetase YP_002346170.1 1273693 D 214092 CDS YP_002346171.1 218928296 1173979 1274876..1275601 1 NC_003143.1 intergral membrane NMN transport protein PnuC 1275601 pnuC 1173979 pnuC Yersinia pestis CO92 intergral membrane NMN transport protein PnuC YP_002346171.1 1274876 D 214092 CDS YP_002346172.1 218928297 1173980 complement(1275716..1276654) 1 NC_003143.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 1276654 1173980 YPO1129 Yersinia pestis CO92 zinc transporter ZitB YP_002346172.1 1275716 R 214092 CDS YP_008479689.1 537470148 16744744 1277103..1278119 1 NC_003143.1 phospho-2-dehydro-3-deoxyheptonate aldolase 1278119 16744744 YPO1129a Yersinia pestis CO92 phospho-2-dehydro-3-deoxyheptonate aldolase YP_008479689.1 1277103 D 214092 CDS YP_002346173.1 218928298 1173982 complement(1278129..1278911) 1 NC_003143.1 transposase/IS protein 1278911 1173982 YPO1131 Yersinia pestis CO92 transposase/IS protein YP_002346173.1 1278129 R 214092 CDS YP_002346174.1 218928299 1173983 complement(1278908..1279930) 1 NC_003143.1 transposase for insertion sequence IS100 1279930 y1093 1173983 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346174.1 1278908 R 214092 CDS YP_002346175.1 218928300 1173984 complement(1280296..1281048) 1 NC_003143.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1281048 gpmA 1173984 gpmA Yersinia pestis CO92 phosphoglyceromutase YP_002346175.1 1280296 R 214092 CDS YP_002346176.1 218928301 1173985 complement(1281395..1281730) 1 NC_003143.1 starvation-inducible protein 1281730 psiF 1173985 psiF Yersinia pestis CO92 starvation-inducible protein YP_002346176.1 1281395 R 214092 CDS YP_002346177.1 218928302 1173987 complement(1283086..1284237) 1 NC_003143.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 1284237 galK 1173987 galK Yersinia pestis CO92 galactokinase YP_002346177.1 1283086 R 214092 CDS YP_002346178.1 218928303 1173988 complement(1284234..1285286) 1 NC_003143.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 1285286 galT 1173988 galT Yersinia pestis CO92 galactose-1-phosphate uridylyltransferase YP_002346178.1 1284234 R 214092 CDS YP_002346179.1 218928304 1173989 complement(1285296..1286312) 1 NC_003143.1 UDP-galactose-4-epimerase 1286312 galE 1173989 galE Yersinia pestis CO92 UDP-galactose-4-epimerase YP_002346179.1 1285296 R 214092 CDS YP_002346180.1 218928305 1173990 complement(1286672..1287490) 1 NC_003143.1 hypothetical protein 1287490 1173990 YPO1140 Yersinia pestis CO92 hypothetical protein YP_002346180.1 1286672 R 214092 CDS YP_002346181.1 218928306 1173991 complement(1287707..1289197) 1 NC_003143.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF 1289197 modF 1173991 modF Yersinia pestis CO92 molybdenum transport ATP-binding protein ModF YP_002346181.1 1287707 R 214092 CDS YP_002346182.1 218928307 1173992 complement(1289307..1290098) 1 NC_003143.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 1290098 modE 1173992 modE Yersinia pestis CO92 DNA-binding transcriptional regulator ModE YP_002346182.1 1289307 R 214092 CDS YP_002346183.1 218928308 1173993 1290415..1290567 1 NC_003143.1 hypothetical protein 1290567 1173993 YPO1144 Yersinia pestis CO92 hypothetical protein YP_002346183.1 1290415 D 214092 CDS YP_002346184.1 218928309 1173994 1290802..1291581 1 NC_003143.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 1291581 modA 1173994 modA Yersinia pestis CO92 molybdate transporter periplasmic protein YP_002346184.1 1290802 D 214092 CDS YP_002346185.1 218928310 1173995 1291581..1292276 1 NC_003143.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 1292276 modB 1173995 modB Yersinia pestis CO92 molybdate ABC transporter permease YP_002346185.1 1291581 D 214092 CDS YP_002346186.1 218928311 1173996 1292270..1293349 1 NC_003143.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 1293349 modC 1173996 modC Yersinia pestis CO92 molybdate transporter ATP-binding protein YP_002346186.1 1292270 D 214092 CDS YP_002346187.1 218928312 1173997 complement(1293405..1294226) 1 NC_003143.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 1294226 1173997 YPO1148 Yersinia pestis CO92 phosphotransferase YP_002346187.1 1293405 R 214092 CDS YP_002346188.1 218928313 1173998 1294517..1295521 1 NC_003143.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 1295521 1173998 YPO1149 Yersinia pestis CO92 6-phosphogluconolactonase YP_002346188.1 1294517 D 214092 CDS YP_002346189.1 218928314 1173999 complement(1295706..1296974) 1 NC_003143.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 1296974 bioA 1173999 bioA Yersinia pestis CO92 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_002346189.1 1295706 R 214092 CDS YP_002346190.1 218928315 1174000 1297073..1298110 1 NC_003143.1 biotin synthase 1298110 bioB 1174000 bioB Yersinia pestis CO92 biotin synthase YP_002346190.1 1297073 D 214092 CDS YP_002346191.1 218928316 1174001 1298110..1299261 1 NC_003143.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 1299261 bioF 1174001 bioF Yersinia pestis CO92 8-amino-7-oxononanoate synthase YP_002346191.1 1298110 D 214092 CDS YP_002346192.1 218928317 1174002 1299245..1300048 1 NC_003143.1 biotin synthesis protein BioC 1300048 bioC 1174002 bioC Yersinia pestis CO92 biotin synthesis protein BioC YP_002346192.1 1299245 D 214092 CDS YP_002346193.1 218928318 1174003 1300041..1300763 1 NC_003143.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1300763 bioD 1174003 bioD Yersinia pestis CO92 dithiobiotin synthetase YP_002346193.1 1300041 D 214092 CDS YP_002346194.1 218928319 1174004 complement(1300915..1301625) 1 NC_003143.1 amino acid transporter 1301625 1174004 YPO1155 Yersinia pestis CO92 amino acid transporter YP_002346194.1 1300915 R 214092 CDS YP_002346195.1 218928320 1174005 1302715..1304730 1 NC_003143.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1304730 uvrB 1174005 uvrB Yersinia pestis CO92 excinuclease ABC subunit B YP_002346195.1 1302715 D 214092 CDS YP_002346196.1 218928321 1174006 1305022..1305267 1 NC_003143.1 hypothetical protein 1305267 1174006 YPO1157 Yersinia pestis CO92 hypothetical protein YP_002346196.1 1305022 D 214092 CDS YP_002346197.1 218928322 1174007 complement(1305398..1306321) 1 NC_003143.1 hypothetical protein 1306321 1174007 YPO1158 Yersinia pestis CO92 hypothetical protein YP_002346197.1 1305398 R 214092 CDS YP_002346198.1 218928323 1174008 1306853..1307833 1 NC_003143.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 1307833 moaA 1174008 moaA Yersinia pestis CO92 molybdenum cofactor biosynthesis protein A YP_002346198.1 1306853 D 214092 CDS YP_002346199.1 218928324 1174009 1307934..1308413 1 NC_003143.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 1308413 moaC 1174009 moaC Yersinia pestis CO92 molybdenum cofactor biosynthesis protein MoaC YP_002346199.1 1307934 D 214092 CDS YP_002346200.1 218928325 1174010 1308410..1308655 1 NC_003143.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 1308655 moaD 1174010 moaD Yersinia pestis CO92 molybdopterin synthase small subunit YP_002346200.1 1308410 D 214092 CDS YP_002346201.1 218928326 1174011 1308655..1309110 1 NC_003143.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 1309110 moaE 1174011 moaE Yersinia pestis CO92 molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_002346201.1 1308655 D 214092 CDS YP_002346202.1 218928327 1174012 1309253..1309963 1 NC_003143.1 hypothetical protein 1309963 1174012 YPO1163 Yersinia pestis CO92 hypothetical protein YP_002346202.1 1309253 D 214092 CDS YP_002346203.1 218928328 1174013 1310198..1310656 1 NC_003143.1 transposase for the IS1541 insertion element 1310656 tnp 1174013 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346203.1 1310198 D 214092 CDS YP_002346204.1 218928329 1174014 complement(1310885..1312588) 1 NC_003143.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 1312588 betA 1174014 betA Yersinia pestis CO92 choline dehydrogenase YP_002346204.1 1310885 R 214092 CDS YP_002346205.1 218928330 1174015 complement(1312611..1314083) 1 NC_003143.1 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 1314083 betB 1174015 betB Yersinia pestis CO92 betaine aldehyde dehydrogenase YP_002346205.1 1312611 R 214092 CDS YP_002346206.1 218928331 1174016 complement(1314141..1314737) 1 NC_003143.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 1314737 betI 1174016 betI Yersinia pestis CO92 transcriptional regulator BetI YP_002346206.1 1314141 R 214092 CDS YP_002346207.1 218928332 1174017 1315102..1317123 1 NC_003143.1 proton-motive-force-driven choline transporter; choline transport protein BetT 1317123 betT 1174017 betT Yersinia pestis CO92 choline transport protein BetT YP_002346207.1 1315102 D 214092 CDS YP_002346208.1 218928333 1174018 1317355..1318248 1 NC_003143.1 DNA-binding transcriptional activator XapR 1318248 1174018 YPO1169 Yersinia pestis CO92 DNA-binding transcriptional activator XapR YP_002346208.1 1317355 D 214092 CDS YP_002346209.1 218928334 1174019 complement(1318286..1319167) 1 NC_003143.1 hypothetical protein 1319167 1174019 YPO1170 Yersinia pestis CO92 hypothetical protein YP_002346209.1 1318286 R 214092 CDS YP_002346210.1 218928335 1174020 1319480..1320343 1 NC_003143.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1320343 xapA 1174020 xapA Yersinia pestis CO92 purine nucleoside phosphorylase YP_002346210.1 1319480 D 214092 CDS YP_008479690.1 537470149 1174021 1320482..1321282 1 NC_003143.1 hypothetical protein 1321282 1174021 YPO1172 Yersinia pestis CO92 hypothetical protein YP_008479690.1 1320482 D 214092 CDS YP_002346211.1 218928336 1174022 1321272..1321730 1 NC_003143.1 transposase for the IS1541 insertion element 1321730 tnp 1174022 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346211.1 1321272 D 214092 CDS YP_002346212.1 218928337 1174023 1322145..1323074 1 NC_003143.1 no significant database hits; hypothetical protein 1323074 1174023 YPO1174 Yersinia pestis CO92 hypothetical protein YP_002346212.1 1322145 D 214092 CDS YP_002346213.1 218928338 1174024 1323368..1324312 1 NC_003143.1 tRNA-dihydrouridine synthase C 1324312 1174024 YPO1175 Yersinia pestis CO92 tRNA-dihydrouridine synthase C YP_002346213.1 1323368 D 214092 CDS YP_008479691.1 537470150 16744745 complement(1324386..1324565) 1 NC_003143.1 membrane protein 1324565 16744745 YPO1175a Yersinia pestis CO92 membrane protein YP_008479691.1 1324386 R 214092 CDS YP_002346214.1 218928339 1174025 1324904..1325839 1 NC_003143.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 1325839 pbpG 1174025 pbpG Yersinia pestis CO92 D-alanyl-D-alanine endopeptidase YP_002346214.1 1324904 D 214092 CDS YP_002346215.1 218928340 1174026 complement(1325960..1327675) 1 NC_003143.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 1327675 dld 1174026 dld Yersinia pestis CO92 D-lactate dehydrogenase YP_002346215.1 1325960 R 214092 CDS YP_002346216.1 218928341 1174027 1327882..1328421 1 NC_003143.1 adenylate cyclase 1328421 cyaB 1174027 cyaB Yersinia pestis CO92 adenylate cyclase YP_002346216.1 1327882 D 214092 CDS YP_002346217.1 218928342 1174028 complement(1328447..1328788) 1 NC_003143.1 hypothetical protein 1328788 1174028 YPO1179 Yersinia pestis CO92 hypothetical protein YP_002346217.1 1328447 R 214092 CDS YP_002346218.1 218928343 1174029 1329101..1330204 1 NC_003143.1 no significant database hits; hypothetical protein 1330204 1174029 YPO1180 Yersinia pestis CO92 hypothetical protein YP_002346218.1 1329101 D 214092 CDS YP_002346219.2 559797713 1174030 1330389..1330637 1 NC_003143.1 hypothetical protein 1330637 1174030 YPO1181 Yersinia pestis CO92 hypothetical protein YP_002346219.2 1330389 D 214092 CDS YP_002346220.1 218928345 1174031 1330845..1331681 1 NC_003143.1 ABC transporter ATP-binding protein 1331681 1174031 YPO1182 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002346220.1 1330845 D 214092 CDS YP_002346221.1 218928346 1174032 1331718..1332647 1 NC_003143.1 substrate-binding periplasmic transport protein 1332647 1174032 YPO1183 Yersinia pestis CO92 substrate-binding periplasmic transport protein YP_002346221.1 1331718 D 214092 CDS YP_002346222.1 218928347 1174033 1332810..1333610 1 NC_003143.1 ABC transport membrane permease 1333610 1174033 YPO1184 Yersinia pestis CO92 ABC transport membrane permease YP_002346222.1 1332810 D 214092 CDS YP_002346223.1 218928348 1174034 1333607..1334494 1 NC_003143.1 ABC transport membrane permease 1334494 1174034 YPO1185 Yersinia pestis CO92 ABC transport membrane permease YP_002346223.1 1333607 D 214092 CDS YP_002346224.1 218928349 1174035 1334740..1335213 1 NC_003143.1 hypothetical protein 1335213 1174035 YPO1186 Yersinia pestis CO92 hypothetical protein YP_002346224.1 1334740 D 214092 CDS YP_002346225.1 218928350 1174036 1335648..1336916 1 NC_003143.1 substrate-binding periplasmic transport protein 1336916 1174036 YPO1187 Yersinia pestis CO92 substrate-binding periplasmic transport protein YP_002346225.1 1335648 D 214092 CDS YP_002346226.1 218928351 1174037 1337040..1338641 1 NC_003143.1 branched-chain amino acid transporter permease 1338641 1174037 YPO1188 Yersinia pestis CO92 branched-chain amino acid transporter permease YP_002346226.1 1337040 D 214092 CDS YP_002346227.1 218928352 1174038 1338641..1339717 1 NC_003143.1 branched-chain amino acid transporter permease 1339717 1174038 YPO1189 Yersinia pestis CO92 branched-chain amino acid transporter permease YP_002346227.1 1338641 D 214092 CDS YP_002346228.1 218928353 1174039 1339714..1340550 1 NC_003143.1 ABC transporter ATP-binding protein 1340550 1174039 YPO1190 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002346228.1 1339714 D 214092 CDS YP_002346229.1 218928354 1174040 1340644..1341342 1 NC_003143.1 ABC transporter ATP-binding protein 1341342 1174040 YPO1191 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002346229.1 1340644 D 214092 CDS YP_002346230.1 218928355 1174041 1341457..1342314 1 NC_003143.1 hypothetical protein 1342314 1174041 YPO1192 Yersinia pestis CO92 hypothetical protein YP_002346230.1 1341457 D 214092 CDS YP_002346231.1 218928356 1174042 1342338..1343753 1 NC_003143.1 pyridoxal-dependent decarboxylase 1343753 1174042 YPO1193 Yersinia pestis CO92 pyridoxal-dependent decarboxylase YP_002346231.1 1342338 D 214092 CDS YP_002346232.1 218928357 1174043 complement(1343908..1344762) 1 NC_003143.1 sulfurtransferase 1344762 1174043 YPO1194 Yersinia pestis CO92 sulfurtransferase YP_002346232.1 1343908 R 214092 CDS YP_002346233.1 218928358 1174045 1346691..1347845 1 NC_003143.1 ABC transporter integral membrane protein 1347845 1174045 YPO1197 Yersinia pestis CO92 ABC transporter integral membrane protein YP_002346233.1 1346691 D 214092 CDS YP_002346234.1 218928359 1174046 1347842..1348780 1 NC_003143.1 ABC transporter ATP-binding protein 1348780 1174046 YPO1198 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002346234.1 1347842 D 214092 CDS YP_002346235.1 218928360 1174047 1348777..1349613 1 NC_003143.1 ABC transporter integral membrane protein 1349613 1174047 YPO1199 Yersinia pestis CO92 ABC transporter integral membrane protein YP_002346235.1 1348777 D 214092 CDS YP_002346236.1 218928361 1174048 1350091..1351425 1 NC_003143.1 arginine:agmatin antiporter 1351425 1174048 YPO1200 Yersinia pestis CO92 arginine:agmatin antiporter YP_002346236.1 1350091 D 214092 CDS YP_002346237.1 218928362 1174049 1351495..1353801 1 NC_003143.1 amino acid decarboxylase 1353801 1174049 YPO1201 Yersinia pestis CO92 amino acid decarboxylase YP_002346237.1 1351495 D 214092 CDS YP_008479692.1 537470151 16744746 complement(1353919..1354137) 1 NC_003143.1 hypothetical protein 1354137 16744746 YPO1203a Yersinia pestis CO92 hypothetical protein YP_008479692.1 1353919 R 214092 CDS YP_002346238.1 218928363 1174050 complement(1354247..1355137) 1 NC_003143.1 hypothetical protein 1355137 1174050 YPO1203 Yersinia pestis CO92 hypothetical protein YP_002346238.1 1354247 R 214092 CDS YP_002346239.1 218928364 1174051 complement(1355549..1356664) 1 NC_003143.1 outer membrane protein OmpC 1356664 ompC2 1174051 ompC2 Yersinia pestis CO92 outer membrane protein OmpC YP_002346239.1 1355549 R 214092 CDS YP_002346240.1 218928365 1174052 1356934..1359114 1 NC_003143.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 1359114 dinG 1174052 dinG Yersinia pestis CO92 ATP-dependent DNA helicase DinG YP_002346240.1 1356934 D 214092 CDS YP_002346241.1 218928366 1174053 complement(1359182..1360624) 1 NC_003143.1 catalase 1360624 katA 1174053 katA Yersinia pestis CO92 catalase YP_002346241.1 1359182 R 214092 CDS YP_002346242.1 218928367 1174054 1360997..1361524 1 NC_003143.1 hypothetical protein 1361524 1174054 YPO1208 Yersinia pestis CO92 hypothetical protein YP_002346242.1 1360997 D 214092 CDS YP_002346243.1 218928368 1174055 complement(1361781..1362989) 1 NC_003143.1 tyrosine-specific transport protein 1362989 tyrP 1174055 tyrP Yersinia pestis CO92 tyrosine-specific transport protein YP_002346243.1 1361781 R 214092 CDS YP_002346244.1 218928369 1174056 1363608..1364801 1 NC_003143.1 competence damage-inducible protein A 1364801 1174056 YPO1210 Yersinia pestis CO92 competence damage-inducible protein A YP_002346244.1 1363608 D 214092 CDS YP_002346245.1 218928370 1174057 complement(1364859..1365368) 1 NC_003143.1 serine protease inhibitor, inhibits trypsin and other proteases; ecotin 1365368 eco 1174057 eco Yersinia pestis CO92 ecotin YP_002346245.1 1364859 R 214092 CDS YP_002346246.1 218928371 1174058 complement(1365403..1365660) 1 NC_003143.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 1365660 1174058 YPO1212 Yersinia pestis CO92 2Fe-2S ferredoxin YP_002346246.1 1365403 R 214092 CDS YP_002346247.1 218928372 1174059 complement(1365664..1366794) 1 NC_003143.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 1366794 nrdB 1174059 nrdB Yersinia pestis CO92 ribonucleotide-diphosphate reductase subunit beta YP_002346247.1 1365664 R 214092 CDS YP_002346248.1 218928373 1174060 complement(1366957..1369245) 1 NC_003143.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1369245 nrdA 1174060 nrdA Yersinia pestis CO92 ribonucleotide-diphosphate reductase subunit alpha YP_002346248.1 1366957 R 214092 CDS YP_002346249.1 218928374 1174061 complement(1369739..1370467) 1 NC_003143.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 1370467 ubiG 1174061 ubiG Yersinia pestis CO92 3-demethylubiquinone-9 3-methyltransferase YP_002346249.1 1369739 R 214092 CDS YP_002346250.1 218928375 1174062 1370729..1373404 1 NC_003143.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1373404 gyrA 1174062 gyrA Yersinia pestis CO92 DNA gyrase subunit A YP_002346250.1 1370729 D 214092 CDS YP_002346251.1 218928376 1174063 1373592..1376465 1 NC_003143.1 hybrid sensory kinase in two-component regulatory system with RcsB and YojN 1376465 rcsC 1174063 rcsC Yersinia pestis CO92 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_002346251.1 1373592 D 214092 CDS YP_002346252.1 218928377 1174064 complement(1376533..1377186) 1 NC_003143.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 1377186 rcsB 1174064 rcsB Yersinia pestis CO92 transcriptional regulator RcsB YP_002346252.1 1376533 R 214092 CDS YP_002346253.1 218928378 1174066 complement(1379905..1381059) 1 NC_003143.1 hypothetical protein 1381059 1174066 YPO1221 Yersinia pestis CO92 hypothetical protein YP_002346253.1 1379905 R 214092 CDS YP_002346254.1 218928379 1174068 1382162..1383277 1 NC_003143.1 allows for ions and hydrophilic solutes to cross the outer membrane; porin 1383277 ompC 1174068 ompC Yersinia pestis CO92 porin YP_002346254.1 1382162 D 214092 CDS YP_002346255.1 218928380 1174069 1383479..1383937 1 NC_003143.1 transposase for the IS1541 insertion element 1383937 tnp 1174069 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346255.1 1383479 D 214092 CDS YP_002346256.1 218928381 1174072 complement(1384727..1385893) 1 NC_003143.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 1385893 ampH 1174072 ampH Yersinia pestis CO92 beta-lactam binding protein AmpH YP_002346256.1 1384727 R 214092 CDS YP_002346257.1 218928382 1174073 complement(1386168..1387664) 1 NC_003143.1 transport protein 1387664 1174073 YPO1226 Yersinia pestis CO92 transport protein YP_002346257.1 1386168 R 214092 CDS YP_002346258.1 218928383 1174074 1388071..1389099 1 NC_003143.1 hypothetical protein 1389099 1174074 YPO1228 Yersinia pestis CO92 hypothetical protein YP_002346258.1 1388071 D 214092 CDS YP_002346259.1 218928384 1174075 complement(1389173..1390960) 1 NC_003143.1 methyl-accepting chemotaxis protein 1390960 cheD2 1174075 cheD2 Yersinia pestis CO92 methyl-accepting chemotaxis protein YP_002346259.1 1389173 R 214092 CDS YP_002346260.1 218928385 1174076 complement(1391382..1392317) 1 NC_003143.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA; outer membrane protease 1392317 pla2 1174076 pla2 Yersinia pestis CO92 outer membrane protease YP_002346260.1 1391382 R 214092 CDS YP_002346261.1 218928386 1174077 complement(1392489..1392731) 1 NC_003143.1 stress response protein 1392731 dinI 1174077 dinI Yersinia pestis CO92 stress response protein YP_002346261.1 1392489 R 214092 CDS YP_002346262.1 218928387 1174078 complement(1392937..1393659) 1 NC_003143.1 prophage repressor protein 1393659 1174078 YPO1233 Yersinia pestis CO92 prophage repressor protein YP_002346262.1 1392937 R 214092 CDS YP_002346263.1 218928388 1174079 1393933..1394412 1 NC_003143.1 phage antitermination protein Q 1394412 1174079 YPO1234 Yersinia pestis CO92 phage antitermination protein Q YP_002346263.1 1393933 D 214092 CDS YP_002346264.1 218928389 1174080 1394614..1395927 1 NC_003143.1 hypothetical protein 1395927 1174080 YPO1235 Yersinia pestis CO92 hypothetical protein YP_002346264.1 1394614 D 214092 CDS YP_002346265.1 218928390 1174081 1395924..1396535 1 NC_003143.1 aldolase 1396535 1174081 YPO1236 Yersinia pestis CO92 aldolase YP_002346265.1 1395924 D 214092 CDS YP_002346266.1 218928391 1174082 1396615..1397430 1 NC_003143.1 transcriptional regulator 1397430 1174082 YPO1237 Yersinia pestis CO92 transcriptional regulator YP_002346266.1 1396615 D 214092 CDS YP_002346267.1 218928392 1174083 1397448..1398200 1 NC_003143.1 hypothetical protein 1398200 1174083 YPO1238 Yersinia pestis CO92 hypothetical protein YP_002346267.1 1397448 D 214092 CDS YP_002346268.1 218928393 1174084 1398814..1399104 1 NC_003143.1 bacteriophage protein 1399104 1174084 YPO1239 Yersinia pestis CO92 bacteriophage protein YP_002346268.1 1398814 D 214092 CDS YP_002346269.1 218928394 1174085 1399150..1399767 1 NC_003143.1 no significant database hits; ATP-binding protein 1399767 1174085 YPO1240 Yersinia pestis CO92 ATP-binding protein YP_002346269.1 1399150 D 214092 CDS YP_002346270.1 218928395 1174086 1399772..1399966 1 NC_003143.1 bacteriophage protein 1399966 1174086 YPO1241 Yersinia pestis CO92 bacteriophage protein YP_002346270.1 1399772 D 214092 CDS YP_002346271.1 218928396 1174087 1399963..1401471 1 NC_003143.1 bacteriophage tail sheath protein 1401471 1174087 YPO1242 Yersinia pestis CO92 bacteriophage tail sheath protein YP_002346271.1 1399963 D 214092 CDS YP_002346272.1 218928397 1174088 1401493..1401861 1 NC_003143.1 no significant database hits; hypothetical protein 1401861 1174088 YPO1243 Yersinia pestis CO92 hypothetical protein YP_002346272.1 1401493 D 214092 CDS YP_002346273.1 218928398 1174089 1401863..1402162 1 NC_003143.1 no significant database hits; hypothetical protein 1402162 1174089 YPO1244 Yersinia pestis CO92 hypothetical protein YP_002346273.1 1401863 D 214092 CDS YP_002346274.1 218928399 1174090 1402283..1403776 1 NC_003143.1 bacteriophage coat protein 1403776 1174090 YPO1245 Yersinia pestis CO92 bacteriophage coat protein YP_002346274.1 1402283 D 214092 CDS YP_002346275.1 218928400 1174091 1404043..1405449 1 NC_003143.1 bacteriophage protein 1405449 1174091 YPO1246 Yersinia pestis CO92 bacteriophage protein YP_002346275.1 1404043 D 214092 CDS YP_002346276.1 218928401 1174092 1405446..1406501 1 NC_003143.1 bacteriophage tail protein 1406501 1174092 YPO1247 Yersinia pestis CO92 bacteriophage tail protein YP_002346276.1 1405446 D 214092 CDS YP_002346277.1 218928402 1174093 1406517..1407113 1 NC_003143.1 bacteriophage baseplate assembly protein 1407113 1174093 YPO1248 Yersinia pestis CO92 bacteriophage baseplate assembly protein YP_002346277.1 1406517 D 214092 CDS YP_002346278.1 218928403 1174094 1407110..1407565 1 NC_003143.1 bacteriophage protein GP46 1407565 1174094 YPO1249 Yersinia pestis CO92 bacteriophage protein GP46 YP_002346278.1 1407110 D 214092 CDS YP_002346279.1 218928404 1174095 1407569..1408705 1 NC_003143.1 bacteriophage protein 1408705 1174095 YPO1250 Yersinia pestis CO92 bacteriophage protein YP_002346279.1 1407569 D 214092 CDS YP_002346280.1 218928405 1174096 1408702..1408962 1 NC_003143.1 bacteriophage protein 1408962 1174096 YPO1250a Yersinia pestis CO92 bacteriophage protein YP_002346280.1 1408702 D 214092 CDS YP_002346281.1 218928406 1174097 1408959..1409306 1 NC_003143.1 bacteriophage protein 1409306 1174097 YPO1251 Yersinia pestis CO92 bacteriophage protein YP_002346281.1 1408959 D 214092 CDS YP_002346282.1 218928407 1174098 1409403..1410182 1 NC_003143.1 bacteriophage tail fiber protein 1410182 stf 1174098 stf Yersinia pestis CO92 bacteriophage tail fiber protein YP_002346282.1 1409403 D 214092 CDS YP_002346283.1 218928408 1174099 1410480..1411220 1 NC_003143.1 LacI family regulatory protein 1411220 1174099 YPO1253 Yersinia pestis CO92 LacI family regulatory protein YP_002346283.1 1410480 D 214092 CDS YP_002346284.1 218928409 1174100 1411511..1412947 1 NC_003143.1 6-phospho-beta-glucosidase 1412947 bglA 1174100 bglA Yersinia pestis CO92 6-phospho-beta-glucosidase YP_002346284.1 1411511 D 214092 CDS YP_002346285.1 218928410 1174101 complement(1413073..1413435) 1 NC_003143.1 No significant database hits; hypothetical protein 1413435 1174101 YPO1255 Yersinia pestis CO92 hypothetical protein YP_002346285.1 1413073 R 214092 CDS YP_002346286.1 218928411 1174102 complement(1414135..1414623) 1 NC_003143.1 No significant database hits; hypothetical protein 1414623 1174102 YPO1257 Yersinia pestis CO92 hypothetical protein YP_002346286.1 1414135 R 214092 CDS YP_002346287.2 537470152 1174103 complement(1414636..1415316) 1 NC_003143.1 hypothetical protein 1415316 1174103 YPO1258 Yersinia pestis CO92 hypothetical protein YP_002346287.2 1414636 R 214092 CDS YP_008479693.1 537470153 1174104 complement(1416141..1416524) 1 NC_003143.1 hypothetical protein 1416524 1174104 YPO1258a Yersinia pestis CO92 hypothetical protein YP_008479693.1 1416141 R 214092 CDS YP_002346289.1 218928414 1174106 complement(1416755..1418551) 1 NC_003143.1 hypothetical protein 1418551 1174106 YPO1260 Yersinia pestis CO92 hypothetical protein YP_002346289.1 1416755 R 214092 CDS YP_002346290.1 218928415 1174107 complement(1418579..1418806) 1 NC_003143.1 hypothetical protein 1418806 1174107 YPO1261 Yersinia pestis CO92 hypothetical protein YP_002346290.1 1418579 R 214092 CDS YP_002346291.1 218928416 1174108 1418984..1419988 1 NC_003143.1 nucleoid-associated protein NdpA 1419988 1174108 YPO1262 Yersinia pestis CO92 nucleoid-associated protein NdpA YP_002346291.1 1418984 D 214092 CDS YP_002346292.1 218928417 1174109 1420189..1420647 1 NC_003143.1 transposase for the IS1541 insertion element 1420647 tnp 1174109 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346292.1 1420189 D 214092 CDS YP_002346293.1 218928418 1174110 complement(1420786..1421070) 1 NC_003143.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1421070 rplY 1174110 rplY Yersinia pestis CO92 50S ribosomal protein L25 YP_002346293.1 1420786 R 214092 CDS YP_002346294.1 218928419 1174111 complement(1421232..1422989) 1 NC_003143.1 DEAD box helicase family protein 1422989 1174111 YPO1265 Yersinia pestis CO92 DEAD box helicase family protein YP_002346294.1 1421232 R 214092 CDS YP_002346295.1 218928420 1174112 1423503..1424210 1 NC_003143.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 1424210 rsuA 1174112 rsuA Yersinia pestis CO92 16S rRNA pseudouridylate synthase A YP_002346295.1 1423503 D 214092 CDS YP_002346296.1 218928421 1174113 1424329..1425528 1 NC_003143.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system 1425528 bcr 1174113 bcr Yersinia pestis CO92 bicyclomycin/multidrug efflux system YP_002346296.1 1424329 D 214092 CDS YP_002346297.1 218928422 1174114 1426495..1426839 1 NC_003143.1 hypothetical protein 1426839 1174114 YPO1269 Yersinia pestis CO92 hypothetical protein YP_002346297.1 1426495 D 214092 CDS YP_002346298.1 218928423 1174115 complement(1426900..1428492) 1 NC_003143.1 ABC transporter ATP-binding protein 1428492 1174115 YPO1270 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002346298.1 1426900 R 214092 CDS YP_002346299.1 218928424 1174116 complement(1428494..1429522) 1 NC_003143.1 ABC transporter integral membrane protein 1429522 1174116 YPO1271 Yersinia pestis CO92 ABC transporter integral membrane protein YP_002346299.1 1428494 R 214092 CDS YP_002346300.1 218928425 1174117 complement(1429522..1430622) 1 NC_003143.1 ABC transporter integral membrane protein 1430622 1174117 YPO1272 Yersinia pestis CO92 ABC transporter integral membrane protein YP_002346300.1 1429522 R 214092 CDS YP_002346301.1 218928426 1174118 complement(1430632..1432440) 1 NC_003143.1 substrate-binding transport protein 1432440 1174118 YPO1273 Yersinia pestis CO92 substrate-binding transport protein YP_002346301.1 1430632 R 214092 CDS YP_002346303.1 218928428 1174120 complement(1434690..1435274) 1 NC_003143.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 1435274 spr 1174120 spr Yersinia pestis CO92 outer membrane lipoprotein YP_002346303.1 1434690 R 214092 CDS YP_002346304.1 218928429 1174121 complement(1435716..1436417) 1 NC_003143.1 hypothetical protein 1436417 1174121 YPO1276 Yersinia pestis CO92 hypothetical protein YP_002346304.1 1435716 R 214092 CDS YP_002346305.1 218928430 1174122 complement(1436476..1437459) 1 NC_003143.1 cobalamin synthesis protein 1437459 1174122 YPO1277 Yersinia pestis CO92 cobalamin synthesis protein YP_002346305.1 1436476 R 214092 CDS YP_002346306.1 218928431 1174123 1437775..1438101 1 NC_003143.1 hypothetical protein 1438101 1174123 YPO1278 Yersinia pestis CO92 hypothetical protein YP_002346306.1 1437775 D 214092 CDS YP_002346307.1 218928432 1174124 1438210..1439010 1 NC_003143.1 transcriptional regulator 1439010 1174124 YPO1279 Yersinia pestis CO92 transcriptional regulator YP_002346307.1 1438210 D 214092 CDS YP_002346308.1 218928433 1174125 complement(1439154..1440626) 1 NC_003143.1 D-mannonate oxidoreductase 1440626 1174125 YPO1280 Yersinia pestis CO92 D-mannonate oxidoreductase YP_002346308.1 1439154 R 214092 CDS YP_002346309.1 218928434 1174126 1441211..1442404 1 NC_003143.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 1442404 uxuA 1174126 uxuA Yersinia pestis CO92 mannonate dehydratase YP_002346309.1 1441211 D 214092 CDS YP_002346310.1 218928435 1174127 complement(1442544..1443116) 1 NC_003143.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 1443116 1174127 YPO1284 Yersinia pestis CO92 elongation factor P YP_002346310.1 1442544 R 214092 CDS YP_002346311.1 218928436 1174128 complement(1443220..1444464) 1 NC_003143.1 tryptophan-specific transport protein 1444464 mtr 1174128 mtr Yersinia pestis CO92 tryptophan-specific transport protein YP_002346311.1 1443220 R 214092 CDS YP_002346312.1 218928437 1174129 1444839..1445093 1 NC_003143.1 hypothetical protein 1445093 1174129 YPO1286 Yersinia pestis CO92 hypothetical protein YP_002346312.1 1444839 D 214092 CDS YP_002346313.1 218928438 1174130 complement(1445162..1445977) 1 NC_003143.1 short chain oxidoreductase 1445977 1174130 YPO1287 Yersinia pestis CO92 short chain oxidoreductase YP_002346313.1 1445162 R 214092 CDS YP_002346314.1 218928439 1174131 complement(1445988..1446953) 1 NC_003143.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein 1446953 1174131 YPO1288 Yersinia pestis CO92 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_002346314.1 1445988 R 214092 CDS YP_002346315.1 218928440 1174132 complement(1446950..1448092) 1 NC_003143.1 hypothetical protein 1448092 1174132 YPO1289 Yersinia pestis CO92 hypothetical protein YP_002346315.1 1446950 R 214092 CDS YP_002346316.1 218928441 1174133 1448444..1449940 1 NC_003143.1 aldehyde dehydrogenase 1449940 1174133 YPO1290 Yersinia pestis CO92 aldehyde dehydrogenase YP_002346316.1 1448444 D 214092 CDS YP_002346317.1 218928442 1174134 1449944..1451497 1 NC_003143.1 carbohydrate kinase 1451497 1174134 YPO1291 Yersinia pestis CO92 carbohydrate kinase YP_002346317.1 1449944 D 214092 CDS YP_002346318.1 218928443 1174135 1451517..1452227 1 NC_003143.1 ribose 5-phosphate isomerase 1452227 rpiA 1174135 rpiA Yersinia pestis CO92 ribose 5-phosphate isomerase YP_002346318.1 1451517 D 214092 CDS YP_002346319.1 218928444 1174136 1452359..1453447 1 NC_003143.1 periplasmic carbohydrate-binding transport protein 1453447 1174136 YPO1293 Yersinia pestis CO92 periplasmic carbohydrate-binding transport protein YP_002346319.1 1452359 D 214092 CDS YP_002346320.1 218928445 1174137 1453556..1455130 1 NC_003143.1 ABC transporter ATP-binding protein 1455130 1174137 YPO1294 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002346320.1 1453556 D 214092 CDS YP_002346321.1 218928446 1174138 1455166..1456164 1 NC_003143.1 ABC transporter integral membrane protein 1456164 1174138 YPO1295 Yersinia pestis CO92 ABC transporter integral membrane protein YP_002346321.1 1455166 D 214092 CDS YP_002346322.1 218928447 1174139 complement(1456277..1456798) 1 NC_003143.1 Mut family protein 1456798 1174139 YPO1296 Yersinia pestis CO92 Mut family protein YP_002346322.1 1456277 R 214092 CDS YP_002346323.1 218928448 1174140 1456994..1458127 1 NC_003143.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein 1458127 fruB 1174140 fruB Yersinia pestis CO92 bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein YP_002346323.1 1456994 D 214092 CDS YP_002346324.1 218928449 1174141 1458124..1459062 1 NC_003143.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 1459062 fruK 1174141 fruK Yersinia pestis CO92 1-phosphofructokinase YP_002346324.1 1458124 D 214092 CDS YP_002346325.1 218928450 1174142 1459077..1460777 1 NC_003143.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunits IIBC 1460777 fruA 1174142 fruA Yersinia pestis CO92 PTS system fructose-specific transporter subunits IIBC YP_002346325.1 1459077 D 214092 CDS YP_002346326.1 218928451 1174143 1461102..1461746 1 NC_003143.1 regulatory protein 1461746 psaE 1174143 psaE Yersinia pestis CO92 regulatory protein YP_002346326.1 1461102 D 214092 CDS YP_002346327.1 218928452 1174144 1461743..1462231 1 NC_003143.1 hypothetical protein 1462231 psaF 1174144 psaF Yersinia pestis CO92 hypothetical protein YP_002346327.1 1461743 D 214092 CDS YP_002346328.1 218928453 1174145 1462776..1463252 1 NC_003143.1 pH 6 antigen (antigen 4) (adhesin) 1463252 psaA 1174145 psaA Yersinia pestis CO92 pH 6 antigen (antigen 4) (adhesin) YP_002346328.1 1462776 D 214092 CDS YP_002346329.1 218928454 1174146 1463379..1464200 1 NC_003143.1 chaperone protein PsaB 1464200 psaB 1174146 psaB Yersinia pestis CO92 chaperone protein PsaB YP_002346329.1 1463379 D 214092 CDS YP_002346330.1 218928455 1174147 1464242..1466755 1 NC_003143.1 outer membrane usher protein PsaC 1466755 psaC 1174147 psaC Yersinia pestis CO92 outer membrane usher protein PsaC YP_002346330.1 1464242 D 214092 CDS YP_002346331.1 218928456 1174148 complement(1466842..1467699) 1 NC_003143.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 1467699 nfo 1174148 nfo Yersinia pestis CO92 endonuclease IV YP_002346331.1 1466842 R 214092 CDS YP_002346332.1 218928457 1174149 complement(1467863..1468951) 1 NC_003143.1 hypothetical protein 1468951 1174149 YPO1307 Yersinia pestis CO92 hypothetical protein YP_002346332.1 1467863 R 214092 CDS YP_002346333.1 218928458 1174150 1469609..1470481 1 NC_003143.1 DNA-binding transcriptional regulator 1470481 1174150 YPO1308 Yersinia pestis CO92 DNA-binding transcriptional regulator YP_002346333.1 1469609 D 214092 CDS YP_002346334.1 218928459 1174151 1470739..1472250 1 NC_003143.1 lysine transporter 1472250 lysP 1174151 lysP Yersinia pestis CO92 lysine transporter YP_002346334.1 1470739 D 214092 CDS YP_002346335.1 218928460 1174152 1472536..1473681 1 NC_003143.1 substrate-binding protein 1473681 1174152 YPO1310 Yersinia pestis CO92 substrate-binding protein YP_002346335.1 1472536 D 214092 CDS YP_002346336.1 218928461 1174153 1473876..1474958 1 NC_003143.1 FecCD family membrane transport protein 1474958 1174153 YPO1311 Yersinia pestis CO92 FecCD family membrane transport protein YP_002346336.1 1473876 D 214092 CDS YP_002346337.1 218928462 1174154 1474955..1475743 1 NC_003143.1 siderophore ABC transporter ATP-binding protein 1475743 1174154 YPO1312 Yersinia pestis CO92 siderophore ABC transporter ATP-binding protein YP_002346337.1 1474955 D 214092 CDS YP_002346338.1 218928463 1174155 1476003..1478000 1 NC_003143.1 YiuR; outer membrane siderophore receptor; outer membrane receptor 1478000 1174155 YPO1313 Yersinia pestis CO92 outer membrane receptor YP_002346338.1 1476003 D 214092 CDS YP_002346339.1 218928464 1174156 complement(1478270..1478890) 1 NC_003143.1 glutathione S-transferase family protein 1478890 1174156 YPO1314 Yersinia pestis CO92 glutathione S-transferase family protein YP_002346339.1 1478270 R 214092 CDS YP_002346340.1 218928465 1174157 complement(1479044..1479694) 1 NC_003143.1 hydrolase 1479694 1174157 YPO1315 Yersinia pestis CO92 hydrolase YP_002346340.1 1479044 R 214092 CDS YP_002346341.1 218928466 1174158 1480181..1481248 1 NC_003143.1 iron/ascorbate oxidoreductase family protein 1481248 1174158 YPO1316 Yersinia pestis CO92 iron/ascorbate oxidoreductase family protein YP_002346341.1 1480181 D 214092 CDS YP_002346342.1 218928467 1174159 1481476..1482300 1 NC_003143.1 hypothetical protein 1482300 1174159 YPO1317 Yersinia pestis CO92 hypothetical protein YP_002346342.1 1481476 D 214092 CDS YP_002346343.1 218928468 1174160 1482297..1483283 1 NC_003143.1 ABC transporter ATP-binding protein 1483283 1174160 YPO1318 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002346343.1 1482297 D 214092 CDS YP_002346344.1 218928469 1174161 1483280..1483951 1 NC_003143.1 ABC transporter integral membrane protein 1483951 1174161 YPO1319 Yersinia pestis CO92 ABC transporter integral membrane protein YP_002346344.1 1483280 D 214092 CDS YP_002346345.1 218928470 1174162 1484193..1485491 1 NC_003143.1 D-alanyl-D-alanine carboxypeptidase 1485491 dacC 1174162 dacC Yersinia pestis CO92 D-alanyl-D-alanine carboxypeptidase YP_002346345.1 1484193 D 214092 CDS YP_002346346.1 218928471 1174163 complement(1485931..1487232) 1 NC_003143.1 serine transporter 1487232 1174163 YPO1321 Yersinia pestis CO92 serine transporter YP_002346346.1 1485931 R 214092 CDS YP_002346347.1 218928472 1174164 complement(1488332..1489096) 1 NC_003143.1 DNA-binding transcriptional repressor DeoR 1489096 deoR 1174164 deoR Yersinia pestis CO92 DNA-binding transcriptional repressor DeoR YP_002346347.1 1488332 R 214092 CDS YP_002346348.1 218928473 1174165 complement(1489326..1489997) 1 NC_003143.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 1489997 deoC 1174165 deoC Yersinia pestis CO92 deoxyribose-phosphate aldolase YP_002346348.1 1489326 R 214092 CDS YP_002346349.1 218928474 1174166 complement(1490255..1490851) 1 NC_003143.1 undecaprenyl pyrophosphate phosphatase 1490851 1174166 YPO1324 Yersinia pestis CO92 undecaprenyl pyrophosphate phosphatase YP_002346349.1 1490255 R 214092 CDS YP_002346350.1 218928475 1174167 complement(1490860..1491675) 1 NC_003143.1 hypothetical protein 1491675 1174167 YPO1325 Yersinia pestis CO92 hypothetical protein YP_002346350.1 1490860 R 214092 CDS YP_002346351.1 218928476 1174168 complement(1492008..1493696) 1 NC_003143.1 hypothetical protein 1493696 1174168 YPO1326 Yersinia pestis CO92 hypothetical protein YP_002346351.1 1492008 R 214092 CDS YP_002346352.1 218928477 1174169 complement(1494106..1494369) 1 NC_003143.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; glutaredoxin 1494369 grxA 1174169 grxA Yersinia pestis CO92 glutaredoxin YP_002346352.1 1494106 R 214092 CDS YP_002346353.1 218928478 1174170 1494832..1495146 1 NC_003143.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function; hypothetical protein 1495146 1174170 YPO1328 Yersinia pestis CO92 hypothetical protein YP_002346353.1 1494832 D 214092 CDS YP_002346354.1 218928479 1174171 1495162..1495281 1 NC_003143.1 No significant database hits; hypothetical protein 1495281 1174171 YPO1329 Yersinia pestis CO92 hypothetical protein YP_002346354.1 1495162 D 214092 CDS YP_002346355.1 218928480 1174172 1495288..1495773 1 NC_003143.1 hypothetical protein 1495773 1174172 YPO1330 Yersinia pestis CO92 hypothetical protein YP_002346355.1 1495288 D 214092 CDS YP_002346356.1 218928481 1174173 1496291..1497400 1 NC_003143.1 putrescine ABC transporter substrate-binding protein 1497400 potF 1174173 potF Yersinia pestis CO92 putrescine ABC transporter substrate-binding protein YP_002346356.1 1496291 D 214092 CDS YP_002346357.1 218928482 1174174 1497571..1498704 1 NC_003143.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 1498704 potG 1174174 potG Yersinia pestis CO92 putrescine ABC transporter ATP-binding protein YP_002346357.1 1497571 D 214092 CDS YP_002346358.1 218928483 1174175 1498729..1499694 1 NC_003143.1 putrescine ABC transporter membrane protein 1499694 potH 1174175 potH Yersinia pestis CO92 putrescine ABC transporter membrane protein YP_002346358.1 1498729 D 214092 CDS YP_002346359.1 218928484 1174176 1499691..1500536 1 NC_003143.1 putrescine ABC transporter membrane protein 1500536 potI 1174176 potI Yersinia pestis CO92 putrescine ABC transporter membrane protein YP_002346359.1 1499691 D 214092 CDS YP_002346360.1 218928485 1174177 1500661..1501125 1 NC_003143.1 hypothetical protein 1501125 1174177 YPO1335 Yersinia pestis CO92 hypothetical protein YP_002346360.1 1500661 D 214092 CDS YP_002346361.1 218928486 1174178 1501209..1502339 1 NC_003143.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1502339 rumB 1174178 rumB Yersinia pestis CO92 23S rRNA methyluridine methyltransferase YP_002346361.1 1501209 D 214092 CDS YP_002346362.1 218928487 1174180 1502827..1503849 1 NC_003143.1 transposase for insertion sequence IS100 1503849 y1093 1174180 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346362.1 1502827 D 214092 CDS YP_002346363.1 218928488 1174181 1503846..1504628 1 NC_003143.1 transposase/IS protein 1504628 1174181 YPO1339 Yersinia pestis CO92 transposase/IS protein YP_002346363.1 1503846 D 214092 CDS YP_002346364.1 218928489 1174182 1505404..1505634 1 NC_003143.1 No significant database hits; hypothetical protein 1505634 1174182 YPO1341 Yersinia pestis CO92 hypothetical protein YP_002346364.1 1505404 D 214092 CDS YP_002346365.1 218928490 1174183 1505975..1506901 1 NC_003143.1 SPFH domain protein 1506901 1174183 YPO1342 Yersinia pestis CO92 SPFH domain protein YP_002346365.1 1505975 D 214092 CDS YP_002346366.1 218928491 1174184 1507268..1508404 1 NC_003143.1 periplasmic binding protein 1508404 1174184 YPO1343 Yersinia pestis CO92 periplasmic binding protein YP_002346366.1 1507268 D 214092 CDS YP_002346368.1 218928493 1174186 1509457..1510242 1 NC_003143.1 transport ATP-binding protein 1510242 1174186 YPO1345 Yersinia pestis CO92 transport ATP-binding protein YP_002346368.1 1509457 D 214092 CDS YP_002346369.1 218928494 1174187 1510239..1511027 1 NC_003143.1 hypothetical protein 1511027 1174187 YPO1346 Yersinia pestis CO92 hypothetical protein YP_002346369.1 1510239 D 214092 CDS YP_002346370.1 218928495 1174188 1511020..1512390 1 NC_003143.1 hypothetical protein 1512390 1174188 YPO1347 Yersinia pestis CO92 hypothetical protein YP_002346370.1 1511020 D 214092 CDS YP_002346371.1 218928496 1174189 1512387..1513232 1 NC_003143.1 hypothetical protein 1513232 1174189 YPO1348 Yersinia pestis CO92 hypothetical protein YP_002346371.1 1512387 D 214092 CDS YP_002346372.1 218928497 1174190 complement(1513422..1514090) 1 NC_003143.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease ArtM 1514090 artM 1174190 artM Yersinia pestis CO92 arginine transporter permease ArtM YP_002346372.1 1513422 R 214092 CDS YP_002346373.1 218928498 1174191 complement(1514090..1514806) 1 NC_003143.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease ArtQ 1514806 artQ 1174191 artQ Yersinia pestis CO92 arginine transporter permease ArtQ YP_002346373.1 1514090 R 214092 CDS YP_002346374.1 218928499 1174192 complement(1514818..1515549) 1 NC_003143.1 arginine-binding periplasmic protein 1 1515549 artI 1174192 artI Yersinia pestis CO92 arginine-binding periplasmic protein 1 YP_002346374.1 1514818 R 214092 CDS YP_002346375.1 218928500 1174193 complement(1515570..1516298) 1 NC_003143.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding protein 1516298 artP 1174193 artP Yersinia pestis CO92 arginine transporter ATP-binding protein YP_002346375.1 1515570 R 214092 CDS YP_002346376.1 218928501 1174194 complement(1516593..1517153) 1 NC_003143.1 catalyzes the interconversion of chorismate to prephenate; chorismate mutase 1517153 1174194 YPO1353 Yersinia pestis CO92 chorismate mutase YP_002346376.1 1516593 R 214092 CDS YP_002346377.1 218928502 1174195 complement(1517323..1517898) 1 NC_003143.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein 1517898 1174195 YPO1354 Yersinia pestis CO92 lipoprotein YP_002346377.1 1517323 R 214092 CDS YP_002346378.1 218928503 1174196 complement(1517995..1519002) 1 NC_003143.1 hypothetical protein 1519002 1174196 YPO1355 Yersinia pestis CO92 hypothetical protein YP_002346378.1 1517995 R 214092 CDS YP_002346379.1 218928504 1174197 complement(1519102..1520592) 1 NC_003143.1 hypothetical protein 1520592 1174197 YPO1356 Yersinia pestis CO92 hypothetical protein YP_002346379.1 1519102 R 214092 CDS YP_002346380.1 218928505 1174198 complement(1520589..1521608) 1 NC_003143.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 1521608 ltaA 1174198 ltaA Yersinia pestis CO92 L-threonine aldolase YP_002346380.1 1520589 R 214092 CDS YP_002346381.1 218928506 1174199 complement(1521957..1523678) 1 NC_003143.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 1523678 poxB 1174199 poxB Yersinia pestis CO92 pyruvate dehydrogenase YP_002346381.1 1521957 R 214092 CDS YP_002346382.1 218928507 1174200 complement(1523822..1524844) 1 NC_003143.1 HCP oxidoreductase, NADH-dependent 1524844 hcr 1174200 hcr Yersinia pestis CO92 HCP oxidoreductase, NADH-dependent YP_002346382.1 1523822 R 214092 CDS YP_002346383.1 218928508 1174201 complement(1524958..1526610) 1 NC_003143.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 1526610 hcp 1174201 hcp Yersinia pestis CO92 hydroxylamine reductase YP_002346383.1 1524958 R 214092 CDS YP_002346384.1 218928509 1174202 complement(1526812..1527708) 1 NC_003143.1 hypothetical protein 1527708 1174202 YPO1361 Yersinia pestis CO92 hypothetical protein YP_002346384.1 1526812 R 214092 CDS YP_002346385.1 218928510 1174203 1528061..1529728 1 NC_003143.1 hypothetical protein 1529728 1174203 YPO1362 Yersinia pestis CO92 hypothetical protein YP_002346385.1 1528061 D 214092 CDS YP_002346386.1 218928511 1174204 complement(1529865..1530812) 1 NC_003143.1 virulence factor 1530812 1174204 YPO1363 Yersinia pestis CO92 virulence factor YP_002346386.1 1529865 R 214092 CDS YP_002346387.1 218928512 1174205 1531046..1532161 1 NC_003143.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 1532161 1174205 YPO1364 Yersinia pestis CO92 macrolide transporter subunit MacA YP_002346387.1 1531046 D 214092 CDS YP_002346388.1 218928513 1174206 1532161..1534110 1 NC_003143.1 with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 1534110 1174206 YPO1365 Yersinia pestis CO92 macrolide transporter ATP-binding /permease YP_002346388.1 1532161 D 214092 CDS YP_002346389.1 218928514 1174207 complement(1534391..1534654) 1 NC_003143.1 cold shock-like protein 1534654 cspD 1174207 cspD Yersinia pestis CO92 cold shock-like protein YP_002346389.1 1534391 R 214092 CDS YP_002346390.1 218928515 1174208 1535015..1535335 1 NC_003143.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1535335 clpS 1174208 clpS Yersinia pestis CO92 ATP-dependent Clp protease adaptor protein ClpS YP_002346390.1 1535015 D 214092 CDS YP_002346391.1 218928516 1174209 1535361..1537637 1 NC_003143.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 1537637 clpA 1174209 clpA Yersinia pestis CO92 ATP-dependent Clp protease ATP-binding subunit YP_002346391.1 1535361 D 214092 CDS YP_002346392.1 218928517 1174210 1537930..1538388 1 NC_003143.1 transposase for the IS1541 insertion element 1538388 tnp 1174210 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346392.1 1537930 D 214092 CDS YP_002346393.1 218928518 1174211 complement(1538760..1538978) 1 NC_003143.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1538978 infA 1174211 infA Yersinia pestis CO92 translation initiation factor IF-1 YP_002346393.1 1538760 R 214092 CDS YP_002346394.1 218928519 1174212 complement(1539144..1539854) 1 NC_003143.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 1539854 aat 1174212 aat Yersinia pestis CO92 leucyl/phenylalanyl-tRNA--protein transferase YP_002346394.1 1539144 R 214092 CDS YP_002346395.1 218928520 1174213 complement(1540073..1541797) 1 NC_003143.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane protein/ATP-binding protein 1541797 cydC 1174213 cydC Yersinia pestis CO92 cysteine/glutathione ABC transporter membrane protein/ATP-binding protein YP_002346395.1 1540073 R 214092 CDS YP_002346396.1 218928521 1174214 complement(1541800..1543584) 1 NC_003143.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane protein/ATP-binding protein 1543584 cydD 1174214 cydD Yersinia pestis CO92 cysteine/glutathione ABC transporter membrane protein/ATP-binding protein YP_002346396.1 1541800 R 214092 CDS YP_002346397.1 218928522 1174215 complement(1544025..1544987) 1 NC_003143.1 thioredoxin reductase 1544987 trxB 1174215 trxB Yersinia pestis CO92 thioredoxin reductase YP_002346397.1 1544025 R 214092 CDS YP_002346398.1 218928523 1174216 1545754..1546248 1 NC_003143.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1546248 lrp 1174216 lrp Yersinia pestis CO92 leucine-responsive transcriptional regulator YP_002346398.1 1545754 D 214092 CDS YP_002346399.1 218928524 1174217 1546371..1550288 1 NC_003143.1 cell division protein 1550288 ftsK 1174217 ftsK Yersinia pestis CO92 cell division protein YP_002346399.1 1546371 D 214092 CDS YP_002346400.1 218928525 1174218 1550481..1551089 1 NC_003143.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1551089 lolA 1174218 lolA Yersinia pestis CO92 outer-membrane lipoprotein carrier protein YP_002346400.1 1550481 D 214092 CDS YP_002346401.1 218928526 1174219 1551100..1552443 1 NC_003143.1 recombination factor protein RarA 1552443 1174219 YPO1378 Yersinia pestis CO92 recombination factor protein RarA YP_002346401.1 1551100 D 214092 CDS YP_002346402.1 218928527 1174220 1552685..1553977 1 NC_003143.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1553977 serS 1174220 serS Yersinia pestis CO92 seryl-tRNA synthetase YP_002346402.1 1552685 D 214092 CDS YP_002346403.1 218928528 1174221 1554240..1555388 1 NC_003143.1 MFS family transporter protein 1555388 1174221 YPO1380 Yersinia pestis CO92 MFS family transporter protein YP_002346403.1 1554240 D 214092 CDS YP_002346404.1 218928529 1174222 complement(1555542..1556276) 1 NC_003143.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1556276 pflA 1174222 pflA Yersinia pestis CO92 pyruvate formate lyase-activating enzyme 1 YP_002346404.1 1555542 R 214092 CDS YP_002346405.1 218928530 1174223 1557263..1557937 1 NC_003143.1 hypothetical protein 1557937 1174223 YPO1382 Yersinia pestis CO92 hypothetical protein YP_002346405.1 1557263 D 214092 CDS YP_002346406.1 218928531 1174224 complement(1558055..1560337) 1 NC_003143.1 formate acetyltransferase 1 1560337 pfl 1174224 pfl Yersinia pestis CO92 formate acetyltransferase 1 YP_002346406.1 1558055 R 214092 CDS YP_002346407.1 218928532 1174225 complement(1560393..1561250) 1 NC_003143.1 formate transporter 1561250 focA 1174225 focA Yersinia pestis CO92 formate transporter YP_002346407.1 1560393 R 214092 CDS YP_002346408.1 218928533 1174226 complement(1561947..1563713) 1 NC_003143.1 hypothetical protein 1563713 1174226 YPO1385 Yersinia pestis CO92 hypothetical protein YP_002346408.1 1561947 R 214092 CDS YP_002346409.1 218928534 1174227 1563862..1564899 1 NC_003143.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 1564899 ansB 1174227 ansB Yersinia pestis CO92 L-asparaginase II YP_002346409.1 1563862 D 214092 CDS YP_002346410.1 218928535 1174228 1565168..1566262 1 NC_003143.1 hypothetical protein 1566262 1174228 YPO1387 Yersinia pestis CO92 hypothetical protein YP_002346410.1 1565168 D 214092 CDS YP_002346411.1 218928536 1174229 1566262..1568130 1 NC_003143.1 hypothetical protein 1568130 1174229 YPO1388 Yersinia pestis CO92 hypothetical protein YP_002346411.1 1566262 D 214092 CDS YP_002346412.1 218928537 1174230 1568497..1569582 1 NC_003143.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1569582 serC 1174230 serC Yersinia pestis CO92 phosphoserine aminotransferase YP_002346412.1 1568497 D 214092 CDS YP_002346413.1 218928538 1174231 1569745..1571031 1 NC_003143.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1571031 aroA 1174231 aroA Yersinia pestis CO92 3-phosphoshikimate 1-carboxyvinyltransferase YP_002346413.1 1569745 D 214092 CDS YP_002346414.1 218928539 1174232 1571344..1572036 1 NC_003143.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1572036 cmk 1174232 cmk Yersinia pestis CO92 cytidylate kinase YP_002346414.1 1571344 D 214092 CDS YP_002346415.1 218928540 1174233 1572210..1573883 1 NC_003143.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1573883 rpsA 1174233 rpsA Yersinia pestis CO92 30S ribosomal protein S1 YP_002346415.1 1572210 D 214092 CDS YP_002346416.1 218928541 1174234 1573944..1574228 1 NC_003143.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1574228 ihfB 1174234 ihfB Yersinia pestis CO92 integration host factor subunit beta YP_002346416.1 1573944 D 214092 CDS YP_002346417.1 218928542 1174235 1574775..1577066 1 NC_003143.1 hypothetical protein 1577066 1174235 YPO1394 Yersinia pestis CO92 hypothetical protein YP_002346417.1 1574775 D 214092 CDS YP_002346418.1 218928543 1174236 1577102..1578850 1 NC_003143.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease 1578850 msbA 1174236 msbA Yersinia pestis CO92 lipid transporter ATP-binding protein/permease YP_002346418.1 1577102 D 214092 CDS YP_002346419.1 218928544 1174237 1578847..1579833 1 NC_003143.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1579833 lpxK 1174237 lpxK Yersinia pestis CO92 tetraacyldisaccharide 4'-kinase YP_002346419.1 1578847 D 214092 CDS YP_002346420.1 218928545 1174238 complement(1579841..1581277) 1 NC_003143.1 hypothetical protein 1581277 1174238 YPO1397 Yersinia pestis CO92 hypothetical protein YP_002346420.1 1579841 R 214092 CDS YP_002346421.1 218928546 1174239 1581996..1582205 1 NC_003143.1 cold shock-like protein 1582205 cspB 1174239 cspB Yersinia pestis CO92 cold shock-like protein YP_002346421.1 1581996 D 214092 CDS YP_002346422.1 218928547 1174240 1582753..1582935 1 NC_003143.1 hypothetical protein 1582935 1174240 YPO1399 Yersinia pestis CO92 hypothetical protein YP_002346422.1 1582753 D 214092 CDS YP_002346423.1 218928548 1174241 1582932..1583684 1 NC_003143.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1583684 kdsB 1174241 kdsB Yersinia pestis CO92 3-deoxy-manno-octulosonate cytidylyltransferase YP_002346423.1 1582932 D 214092 CDS YP_002346424.1 218928549 1174242 1584047..1584940 1 NC_003143.1 hypothetical protein 1584940 1174242 YPO1401 Yersinia pestis CO92 hypothetical protein YP_002346424.1 1584047 D 214092 CDS YP_002346425.1 218928550 1174243 1585713..1586498 1 NC_003143.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 1586498 smtA 1174243 smtA Yersinia pestis CO92 metallothionein SmtA YP_002346425.1 1585713 D 214092 CDS YP_002346426.1 218928551 1174244 1586495..1587817 1 NC_003143.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1587817 mukF 1174244 mukF Yersinia pestis CO92 condesin subunit F YP_002346426.1 1586495 D 214092 CDS YP_002346427.1 218928552 1174245 1587825..1588526 1 NC_003143.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1588526 mukE 1174245 mukE Yersinia pestis CO92 condesin subunit E YP_002346427.1 1587825 D 214092 CDS YP_002346428.1 218928553 1174246 1588523..1592980 1 NC_003143.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1592980 mukB 1174246 mukB Yersinia pestis CO92 cell division protein MukB YP_002346428.1 1588523 D 214092 CDS YP_002346429.1 218928554 1174247 1593196..1593654 1 NC_003143.1 transposase for the IS1541 insertion element 1593654 tnp 1174247 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346429.1 1593196 D 214092 CDS YP_002346430.1 218928555 1174248 1593938..1595794 1 NC_003143.1 hypothetical protein 1595794 1174248 YPO1407 Yersinia pestis CO92 hypothetical protein YP_002346430.1 1593938 D 214092 CDS YP_002346431.1 218928556 1174249 1596018..1596566 1 NC_003143.1 hypothetical protein 1596566 1174249 YPO1408 Yersinia pestis CO92 hypothetical protein YP_002346431.1 1596018 D 214092 CDS YP_002346432.1 218928557 1174250 1596627..1597274 1 NC_003143.1 metallo-beta-lactamase superfamily protein 1597274 1174250 YPO1409 Yersinia pestis CO92 metallo-beta-lactamase superfamily protein YP_002346432.1 1596627 D 214092 CDS YP_002346433.1 218928558 1174251 complement(1597698..1598888) 1 NC_003143.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1598888 aspC 1174251 aspC Yersinia pestis CO92 aromatic amino acid aminotransferase YP_002346433.1 1597698 R 214092 CDS YP_002346434.1 218928559 1174252 complement(1599145..1600227) 1 NC_003143.1 porin 1600227 ompF 1174252 ompF Yersinia pestis CO92 porin YP_002346434.1 1599145 R 214092 CDS YP_002346435.1 218928560 1174253 complement(1600525..1601925) 1 NC_003143.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1601925 asnC 1174253 asnC Yersinia pestis CO92 asparaginyl-tRNA synthetase YP_002346435.1 1600525 R 214092 CDS YP_002346436.1 218928561 1174254 complement(1602424..1603629) 1 NC_003143.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1603629 pncB 1174254 pncB Yersinia pestis CO92 nicotinate phosphoribosyltransferase YP_002346436.1 1602424 R 214092 CDS YP_002346437.1 218928562 1174255 1604345..1606960 1 NC_003143.1 aminopeptidase 1606960 pepN 1174255 pepN Yersinia pestis CO92 aminopeptidase YP_002346437.1 1604345 D 214092 CDS YP_002346438.1 218928563 1174256 1607578..1608588 1 NC_003143.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1608588 pyrD 1174256 pyrD Yersinia pestis CO92 dihydroorotate dehydrogenase 2 YP_002346438.1 1607578 D 214092 CDS YP_002346439.1 218928564 1174257 1608771..1609322 1 NC_003143.1 hypothetical protein 1609322 1174257 YPO1416 Yersinia pestis CO92 hypothetical protein YP_002346439.1 1608771 D 214092 CDS YP_002346440.1 218928565 1174258 complement(1609348..1610460) 1 NC_003143.1 iron-sulfur binding protein 1610460 1174258 YPO1417 Yersinia pestis CO92 iron-sulfur binding protein YP_002346440.1 1609348 R 214092 CDS YP_002346441.1 218928566 1174259 1610560..1612680 1 NC_003143.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1612680 rlmL 1174259 rlmL Yersinia pestis CO92 23S rRNA m(2)G2445 methyltransferase YP_002346441.1 1610560 D 214092 CDS YP_002346442.1 218928567 1174260 1612686..1614599 1 NC_003143.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1614599 uup 1174260 uup Yersinia pestis CO92 ABC transporter ATPase YP_002346442.1 1612686 D 214092 CDS YP_002346443.1 218928568 1174261 1614728..1616014 1 NC_003143.1 paraquat-inducible protein A 1616014 pqiA 1174261 pqiA Yersinia pestis CO92 paraquat-inducible protein A YP_002346443.1 1614728 D 214092 CDS YP_002346444.1 218928569 1174262 1616028..1617653 1 NC_003143.1 paraquat-inducible protein B 1617653 pqiB 1174262 pqiB Yersinia pestis CO92 paraquat-inducible protein B YP_002346444.1 1616028 D 214092 CDS YP_002346445.1 218928570 1174263 1617650..1618228 1 NC_003143.1 lipoprotein 1618228 1174263 YPO1422 Yersinia pestis CO92 lipoprotein YP_002346445.1 1617650 D 214092 CDS YP_002346446.1 218928571 1174264 1618277..1618417 1 NC_003143.1 No significant database hits; hypothetical protein 1618417 1174264 YPO1423 Yersinia pestis CO92 hypothetical protein YP_002346446.1 1618277 D 214092 CDS YP_002346447.1 218928572 1174265 1618498..1618665 1 NC_003143.1 ribosome modulation factor 1618665 rmf 1174265 rmf Yersinia pestis CO92 ribosome modulation factor YP_002346447.1 1618498 D 214092 CDS YP_002346448.1 218928573 1174266 1618863..1619321 1 NC_003143.1 transposase for the IS1541 insertion element 1619321 tnp 1174266 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346448.1 1618863 D 214092 CDS YP_008479694.1 537470154 16744747 complement(1619438..1620421) 1 NC_003143.1 3-oxoacyl-ACP synthase 1620421 16744747 YPO1425a Yersinia pestis CO92 3-oxoacyl-ACP synthase YP_008479694.1 1619438 R 214092 CDS YP_002346449.1 218928574 1174268 complement(1620482..1621264) 1 NC_003143.1 transposase/IS protein 1621264 1174268 YPO1426 Yersinia pestis CO92 transposase/IS protein YP_002346449.1 1620482 R 214092 CDS YP_002346450.1 218928575 1174269 complement(1621261..1622283) 1 NC_003143.1 transposase for insertion sequence IS100 1622283 y1093 1174269 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346450.1 1621261 R 214092 CDS YP_008479695.1 537470155 16744748 complement(1622297..1622707) 1 NC_003143.1 hypothetical protein 1622707 16744748 YPO1427b Yersinia pestis CO92 hypothetical protein YP_008479695.1 1622297 R 214092 CDS YP_002346452.1 218928577 1174271 complement(1623371..1623889) 1 NC_003143.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1623889 fabA 1174271 fabA Yersinia pestis CO92 3-hydroxydecanoyl-ACP dehydratase YP_002346452.1 1623371 R 214092 CDS YP_002346453.1 218928578 1174272 complement(1623958..1625730) 1 NC_003143.1 Lon protease 1625730 1174272 YPO1431 Yersinia pestis CO92 Lon protease YP_002346453.1 1623958 R 214092 CDS YP_002346454.1 218928579 1174273 1625920..1626375 1 NC_003143.1 hypothetical protein 1626375 1174273 YPO1433 Yersinia pestis CO92 hypothetical protein YP_002346454.1 1625920 D 214092 CDS YP_002346455.1 218928580 1174274 complement(1626544..1627002) 1 NC_003143.1 transposase for the IS1541 insertion element 1627002 tnp 1174274 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346455.1 1626544 R 214092 CDS YP_002346456.1 218928581 1174275 complement(1627192..1628253) 1 NC_003143.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein OmpA 1628253 ompA 1174275 ompA Yersinia pestis CO92 outer membrane protein OmpA YP_002346456.1 1627192 R 214092 CDS YP_002346457.1 218928582 1174276 complement(1628611..1629117) 1 NC_003143.1 SOS cell division inhibitor 1629117 sulA 1174276 sulA Yersinia pestis CO92 SOS cell division inhibitor YP_002346457.1 1628611 R 214092 CDS YP_002346458.1 218928583 1174277 1629346..1629981 1 NC_003143.1 hypothetical protein 1629981 1174277 YPO1437 Yersinia pestis CO92 hypothetical protein YP_002346458.1 1629346 D 214092 CDS YP_002346459.1 218928584 1174278 complement(1630083..1632221) 1 NC_003143.1 hypothetical protein 1632221 1174278 YPO1438 Yersinia pestis CO92 hypothetical protein YP_002346459.1 1630083 R 214092 CDS YP_002346460.1 218928585 1174279 complement(1632251..1632697) 1 NC_003143.1 hypothetical protein 1632697 1174279 YPO1439 Yersinia pestis CO92 hypothetical protein YP_002346460.1 1632251 R 214092 CDS YP_002346461.1 218928586 1174280 1632891..1634876 1 NC_003143.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1634876 helD 1174280 helD Yersinia pestis CO92 DNA helicase IV YP_002346461.1 1632891 D 214092 CDS YP_002346462.1 218928587 1174281 complement(1634937..1635401) 1 NC_003143.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1635401 mgsA 1174281 mgsA Yersinia pestis CO92 methylglyoxal synthase YP_002346462.1 1634937 R 214092 CDS YP_002346463.1 218928588 1174282 complement(1635580..1636260) 1 NC_003143.1 hypothetical protein 1636260 1174282 YPO1442 Yersinia pestis CO92 hypothetical protein YP_002346463.1 1635580 R 214092 CDS YP_002346464.1 218928589 1174283 1636576..1636992 1 NC_003143.1 hypothetical protein 1636992 1174283 YPO1443 Yersinia pestis CO92 hypothetical protein YP_002346464.1 1636576 D 214092 CDS YP_002346465.1 218928590 1174284 complement(1637101..1637442) 1 NC_003143.1 heat shock protein HspQ 1637442 1174284 YPO1444 Yersinia pestis CO92 heat shock protein HspQ YP_002346465.1 1637101 R 214092 CDS YP_002346466.1 218928591 1174285 complement(1637479..1638669) 1 NC_003143.1 hypothetical protein 1638669 1174285 YPO1445 Yersinia pestis CO92 hypothetical protein YP_002346466.1 1637479 R 214092 CDS YP_002346467.1 218928592 1174286 1638763..1639041 1 NC_003143.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1639041 1174286 YPO1446 Yersinia pestis CO92 acylphosphatase YP_002346467.1 1638763 D 214092 CDS YP_002346468.1 218928593 1174287 complement(1639093..1639419) 1 NC_003143.1 sulfite reductase subunit protein 1639419 1174287 YPO1447 Yersinia pestis CO92 sulfite reductase subunit protein YP_002346468.1 1639093 R 214092 CDS YP_008479696.1 537470156 16744749 1640152..1640457 1 NC_003143.1 hypothetical protein 1640457 16744749 YPO1450a Yersinia pestis CO92 hypothetical protein YP_008479696.1 1640152 D 214092 CDS YP_008479697.1 537470157 16744750 1640821..1641183 1 NC_003143.1 hypothetical protein 1641183 16744750 YPO1450b Yersinia pestis CO92 hypothetical protein YP_008479697.1 1640821 D 214092 CDS YP_008479698.1 537470158 16744751 1641190..1641468 1 NC_003143.1 hypothetical protein 1641468 16744751 YPO1450c Yersinia pestis CO92 hypothetical protein YP_008479698.1 1641190 D 214092 CDS YP_008479699.1 537470159 16744752 1641453..1642634 1 NC_003143.1 hypothetical protein 1642634 16744752 YPO1450d Yersinia pestis CO92 hypothetical protein YP_008479699.1 1641453 D 214092 CDS YP_002346469.1 218928594 1174291 complement(1643068..1645485) 1 NC_003143.1 oxidoreductase 1645485 1174291 YPO1451 Yersinia pestis CO92 oxidoreductase YP_002346469.1 1643068 R 214092 CDS YP_002346470.1 218928595 1174292 complement(1645639..1646385) 1 NC_003143.1 short chain dehydrogenase 1646385 1174292 YPO1452 Yersinia pestis CO92 short chain dehydrogenase YP_002346470.1 1645639 R 214092 CDS YP_002346471.1 218928596 1174293 1647014..1647334 1 NC_003143.1 No significant database hits; hypothetical protein 1647334 1174293 YPO1453 Yersinia pestis CO92 hypothetical protein YP_002346471.1 1647014 D 214092 CDS YP_002346472.1 218928597 1174294 1647664..1648122 1 NC_003143.1 (3R)-hydroxymyristoyl-ACP dehydratase 1648122 1174294 YPO1454 Yersinia pestis CO92 (3R)-hydroxymyristoyl-ACP dehydratase YP_002346472.1 1647664 D 214092 CDS YP_002346473.1 218928598 1174295 1648112..1649395 1 NC_003143.1 beta-ketoacyl-ACP synthase 1649395 1174295 YPO1455 Yersinia pestis CO92 beta-ketoacyl-ACP synthase YP_002346473.1 1648112 D 214092 CDS YP_002346474.1 218928599 1174296 1649388..1650134 1 NC_003143.1 3-ketoacyl-ACP reductase 1650134 1174296 YPO1456 Yersinia pestis CO92 3-ketoacyl-ACP reductase YP_002346474.1 1649388 D 214092 CDS YP_002346475.1 218928600 1174297 1650150..1651388 1 NC_003143.1 hydroxymethylglutaryl-coenzyme A synthase 1651388 1174297 YPO1457 Yersinia pestis CO92 hydroxymethylglutaryl-coenzyme A synthase YP_002346475.1 1650150 D 214092 CDS YP_002346476.1 218928601 1174298 1651381..1652100 1 NC_003143.1 enoyl-CoA hydratase 1652100 1174298 YPO1458 Yersinia pestis CO92 enoyl-CoA hydratase YP_002346476.1 1651381 D 214092 CDS YP_002346477.1 218928602 1174299 1652093..1652854 1 NC_003143.1 involved in polyketide production; polyketide biosynthesis enoyl-CoA hydratase 1652854 1174299 YPO1459 Yersinia pestis CO92 polyketide biosynthesis enoyl-CoA hydratase YP_002346477.1 1652093 D 214092 CDS YP_002346478.1 218928603 1174300 1652857..1653645 1 NC_003143.1 short chain dehydrogenase 1653645 1174300 YPO1460 Yersinia pestis CO92 short chain dehydrogenase YP_002346478.1 1652857 D 214092 CDS YP_002346479.1 218928604 1174301 1653684..1654172 1 NC_003143.1 hypothetical protein 1654172 1174301 YPO1461 Yersinia pestis CO92 hypothetical protein YP_002346479.1 1653684 D 214092 CDS YP_002346480.1 218928605 1174302 1654210..1654458 1 NC_003143.1 acyl carrier protein 1654458 1174302 YPO1462 Yersinia pestis CO92 acyl carrier protein YP_002346480.1 1654210 D 214092 CDS YP_002346481.1 218928606 1174303 1654557..1655405 1 NC_003143.1 acyl transferase 1655405 1174303 YPO1463 Yersinia pestis CO92 acyl transferase YP_002346481.1 1654557 D 214092 CDS YP_002346483.1 218928608 1174305 1656394..1656894 1 NC_003143.1 hypothetical protein 1656894 1174305 YPO1465 Yersinia pestis CO92 hypothetical protein YP_002346483.1 1656394 D 214092 CDS YP_002346484.1 218928609 1174306 1656937..1658487 1 NC_003143.1 hypothetical protein 1658487 1174306 YPO1466 Yersinia pestis CO92 hypothetical protein YP_002346484.1 1656937 D 214092 CDS YP_002346485.1 218928610 1174307 1658499..1659851 1 NC_003143.1 hypothetical protein 1659851 1174307 YPO1467 Yersinia pestis CO92 hypothetical protein YP_002346485.1 1658499 D 214092 CDS YP_002346486.1 218928611 1174308 1659848..1660534 1 NC_003143.1 hypothetical protein 1660534 1174308 YPO1468 Yersinia pestis CO92 hypothetical protein YP_002346486.1 1659848 D 214092 CDS YP_002346487.1 218928612 1174309 1660534..1662270 1 NC_003143.1 hypothetical protein 1662270 1174309 YPO1469 Yersinia pestis CO92 hypothetical protein YP_002346487.1 1660534 D 214092 CDS YP_002346488.1 218928613 1174310 1662274..1662765 1 NC_003143.1 hypothetical protein 1662765 1174310 YPO1470 Yersinia pestis CO92 hypothetical protein YP_002346488.1 1662274 D 214092 CDS YP_002346489.1 218928614 1174311 1663153..1665795 1 NC_003143.1 ATPase subunit of ATP-dependent protease 1665795 1174311 YPO1471 Yersinia pestis CO92 ATPase subunit of ATP-dependent protease YP_002346489.1 1663153 D 214092 CDS YP_002346490.1 218928615 1174312 1665798..1668146 1 NC_003143.1 hypothetical protein 1668146 1174312 YPO1472 Yersinia pestis CO92 hypothetical protein YP_002346490.1 1665798 D 214092 CDS YP_002346491.1 218928616 1174313 1668162..1670462 1 NC_003143.1 No significant database hits. Similar to YPO0966 (83.2% identity in 768 aa overlap) and YPO1476 (51.9% identity in 567 aa overlap); hypothetical protein 1670462 1174313 YPO1473 Yersinia pestis CO92 hypothetical protein YP_002346491.1 1668162 D 214092 CDS YP_002346492.1 218928617 1174314 1670459..1671232 1 NC_003143.1 hypothetical protein 1671232 1174314 YPO1474 Yersinia pestis CO92 hypothetical protein YP_002346492.1 1670459 D 214092 CDS YP_002346493.1 218928618 1174315 1671386..1671646 1 NC_003143.1 hypothetical protein 1671646 1174315 YPO1475 Yersinia pestis CO92 hypothetical protein YP_002346493.1 1671386 D 214092 CDS YP_002346494.1 218928619 1174316 1671662..1673845 1 NC_003143.1 hypothetical protein 1673845 1174316 YPO1476 Yersinia pestis CO92 hypothetical protein YP_002346494.1 1671662 D 214092 CDS YP_008479700.1 537470160 16744753 complement(1675221..1675541) 1 NC_003143.1 hypothetical protein 1675541 16744753 YPO1477a Yersinia pestis CO92 hypothetical protein YP_008479700.1 1675221 R 214092 CDS YP_002346496.1 218928621 1174319 1676764..1677885 1 NC_003143.1 hypothetical protein 1677885 1174319 YPO1481 Yersinia pestis CO92 hypothetical protein YP_002346496.1 1676764 D 214092 CDS YP_002346497.1 218928622 1174320 1677882..1681304 1 NC_003143.1 hypothetical protein 1681304 1174320 YPO1482 Yersinia pestis CO92 hypothetical protein YP_002346497.1 1677882 D 214092 CDS YP_002346498.1 218928623 1174321 1681348..1682949 1 NC_003143.1 hypothetical protein 1682949 1174321 YPO1483 Yersinia pestis CO92 hypothetical protein YP_002346498.1 1681348 D 214092 CDS YP_002346499.1 218928624 1174322 1682940..1684025 1 NC_003143.1 No significant database hits. N-terminal region is similar to the N-terminus of YPO0873 (62.1% identity in 124 aa overlap); hypothetical protein 1684025 1174322 YPO1484 Yersinia pestis CO92 hypothetical protein YP_002346499.1 1682940 D 214092 CDS YP_002346500.1 218928625 1174323 1684025..1684495 1 NC_003143.1 No significant database hits; hypothetical protein 1684495 1174323 YPO1484a Yersinia pestis CO92 hypothetical protein YP_002346500.1 1684025 D 214092 CDS YP_002346501.1 218928626 1174324 1684716..1686479 1 NC_003143.1 hypothetical protein 1686479 1174324 YPO1485 Yersinia pestis CO92 hypothetical protein YP_002346501.1 1684716 D 214092 CDS YP_002346502.1 218928627 1174325 1686443..1687528 1 NC_003143.1 hypothetical protein 1687528 1174325 YPO1486 Yersinia pestis CO92 hypothetical protein YP_002346502.1 1686443 D 214092 CDS YP_002346503.1 218928628 1174326 1687596..1688084 1 NC_003143.1 hypothetical protein 1688084 1174326 YPO1487 Yersinia pestis CO92 hypothetical protein YP_002346503.1 1687596 D 214092 CDS YP_002346504.1 218928629 1174327 1688084..1688536 1 NC_003143.1 hypothetical protein 1688536 1174327 YPO1488 Yersinia pestis CO92 hypothetical protein YP_002346504.1 1688084 D 214092 CDS YP_002346505.1 218928630 1174328 1688561..1689928 1 NC_003143.1 hypothetical protein 1689928 1174328 YPO1489 Yersinia pestis CO92 hypothetical protein YP_002346505.1 1688561 D 214092 CDS YP_002346506.1 218928631 1174329 complement(1690140..1690763) 1 NC_003143.1 hypothetical protein 1690763 1174329 YPO1490 Yersinia pestis CO92 hypothetical protein YP_002346506.1 1690140 R 214092 CDS YP_002346507.1 218928632 1174330 1691446..1693041 1 NC_003143.1 ABC transporter ATP-binding protein 1693041 ybiT 1174330 ybiT Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002346507.1 1691446 D 214092 CDS YP_002346508.1 218928633 1174331 1693269..1693922 1 NC_003143.1 hypothetical protein 1693922 1174331 YPO1492 Yersinia pestis CO92 hypothetical protein YP_002346508.1 1693269 D 214092 CDS YP_002346509.1 218928634 1174332 complement(1693966..1695174) 1 NC_003143.1 transposase 1695174 y1062 1174332 y1062 Yersinia pestis CO92 transposase YP_002346509.1 1693966 R 214092 CDS YP_002346510.1 218928635 1174333 complement(1695310..1696077) 1 NC_003143.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 1696077 moeB 1174333 moeB Yersinia pestis CO92 molybdopterin biosynthesis protein MoeB YP_002346510.1 1695310 R 214092 CDS YP_002346511.1 218928636 1174334 complement(1696082..1697356) 1 NC_003143.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 1697356 moeA 1174334 moeA Yersinia pestis CO92 molybdopterin biosynthesis protein MoeA YP_002346511.1 1696082 R 214092 CDS YP_002346512.1 218928637 1174335 complement(1697891..1699201) 1 NC_003143.1 heme-binding protein 1699201 1174335 YPO1496 Yersinia pestis CO92 heme-binding protein YP_002346512.1 1697891 R 214092 CDS YP_002346513.1 218928638 1174336 complement(1699211..1699879) 1 NC_003143.1 ABC transporter ATP-binding protein 1699879 1174336 YPO1497 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002346513.1 1699211 R 214092 CDS YP_002346514.1 218928639 1174337 complement(1699881..1701143) 1 NC_003143.1 hypothetical protein 1701143 1174337 YPO1498 Yersinia pestis CO92 hypothetical protein YP_002346514.1 1699881 R 214092 CDS YP_002346515.1 218928640 1174338 complement(1701145..1703505) 1 NC_003143.1 hypothetical protein 1703505 1174338 YPO1499 Yersinia pestis CO92 hypothetical protein YP_002346515.1 1701145 R 214092 CDS YP_002346516.1 218928641 1174339 complement(1703589..1703801) 1 NC_003143.1 No significant database hits; hypothetical protein 1703801 1174339 YPO1500 Yersinia pestis CO92 hypothetical protein YP_002346516.1 1703589 R 214092 CDS YP_002346517.1 218928642 1174340 complement(1704058..1704900) 1 NC_003143.1 esterase 1704900 1174340 YPO1501 Yersinia pestis CO92 esterase YP_002346517.1 1704058 R 214092 CDS YP_002346518.1 218928643 1174341 complement(1704921..1706054) 1 NC_003143.1 alcohol dehydrogenase 1706054 1174341 YPO1502 Yersinia pestis CO92 alcohol dehydrogenase YP_002346518.1 1704921 R 214092 CDS YP_002346519.1 218928644 1174342 complement(1706334..1707203) 1 NC_003143.1 LysR family transcriptional regulator 1707203 1174342 YPO1503 Yersinia pestis CO92 LysR family transcriptional regulator YP_002346519.1 1706334 R 214092 CDS YP_002346520.1 218928645 1174343 1707339..1708490 1 NC_003143.1 hypothetical protein 1708490 1174343 YPO1504 Yersinia pestis CO92 hypothetical protein YP_002346520.1 1707339 D 214092 CDS YP_002346521.1 218928646 1174344 1708674..1709336 1 NC_003143.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1709336 folE 1174344 folE Yersinia pestis CO92 GTP cyclohydrolase I YP_002346521.1 1708674 D 214092 CDS YP_002346522.1 218928647 1174345 1709391..1710557 1 NC_003143.1 hypothetical protein 1710557 yeiB 1174345 yeiB Yersinia pestis CO92 hypothetical protein YP_002346522.1 1709391 D 214092 CDS YP_002346523.1 218928648 1174346 1711305..1712312 1 NC_003143.1 galactose-binding protein 1712312 mglB 1174346 mglB Yersinia pestis CO92 galactose-binding protein YP_002346523.1 1711305 D 214092 CDS YP_002346524.1 218928649 1174347 1712542..1714062 1 NC_003143.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 1714062 mglA 1174347 mglA Yersinia pestis CO92 galactose/methyl galaxtoside transporter ATP-binding protein YP_002346524.1 1712542 D 214092 CDS YP_002346525.1 218928650 1174348 1714083..1715093 1 NC_003143.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 1715093 mglC 1174348 mglC Yersinia pestis CO92 beta-methylgalactoside transporter inner membrane protein YP_002346525.1 1714083 D 214092 CDS YP_002346526.1 218928651 1174349 complement(1715538..1716275) 1 NC_003143.1 hypothetical protein 1716275 sanA 1174349 sanA Yersinia pestis CO92 hypothetical protein YP_002346526.1 1715538 R 214092 CDS YP_002346527.1 218928652 1174350 complement(1716556..1718253) 1 NC_003143.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1718253 sfcA 1174350 sfcA Yersinia pestis CO92 malate dehydrogenase YP_002346527.1 1716556 R 214092 CDS YP_002346528.1 218928653 1174351 complement(1718609..1719493) 1 NC_003143.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 1719493 cdd 1174351 cdd Yersinia pestis CO92 cytidine deaminase YP_002346528.1 1718609 R 214092 CDS YP_002346529.1 218928654 1174352 complement(1719819..1720514) 1 NC_003143.1 hypothetical protein 1720514 yohK 1174352 yohK Yersinia pestis CO92 hypothetical protein YP_002346529.1 1719819 R 214092 CDS YP_002346530.1 218928655 1174353 complement(1720511..1720918) 1 NC_003143.1 hypothetical protein 1720918 yohJ 1174353 yohJ Yersinia pestis CO92 hypothetical protein YP_002346530.1 1720511 R 214092 CDS YP_002346531.1 218928656 1174354 complement(1721160..1722341) 1 NC_003143.1 multidrug resistance protein 1722341 1174354 YPO1515 Yersinia pestis CO92 multidrug resistance protein YP_002346531.1 1721160 R 214092 CDS YP_002346532.1 218928657 1174355 complement(1722674..1723930) 1 NC_003143.1 No significant database hits; hypothetical protein 1723930 1174355 YPO1516 Yersinia pestis CO92 hypothetical protein YP_002346532.1 1722674 R 214092 CDS YP_002346533.1 218928658 1174356 complement(1723945..1725036) 1 NC_003143.1 sugar ABC transporter 1725036 1174356 YPO1517 Yersinia pestis CO92 sugar ABC transporter YP_002346533.1 1723945 R 214092 CDS YP_002346535.1 218928660 1174358 complement(1726646..1727428) 1 NC_003143.1 transposase/IS protein 1727428 1174358 YPO1519 Yersinia pestis CO92 transposase/IS protein YP_002346535.1 1726646 R 214092 CDS YP_002346536.1 218928661 1174359 complement(1727425..1728447) 1 NC_003143.1 transposase for insertion sequence IS100 1728447 y1093 1174359 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346536.1 1727425 R 214092 CDS YP_002346537.1 218928662 1174360 1728558..1729016 1 NC_003143.1 transposase for the IS1541 insertion element 1729016 tnp 1174360 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346537.1 1728558 D 214092 CDS YP_002346538.1 218928663 1174361 complement(1729180..1731207) 1 NC_003143.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 1731207 metG 1174361 metG Yersinia pestis CO92 methionyl-tRNA synthetase YP_002346538.1 1729180 R 214092 CDS YP_002346539.1 218928664 1174362 1731472..1732584 1 NC_003143.1 ATPase 1732584 1174362 YPO1523 Yersinia pestis CO92 ATPase YP_002346539.1 1731472 D 214092 CDS YP_002346540.1 218928665 1174363 1732829..1733470 1 NC_003143.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1733470 udk 1174363 udk Yersinia pestis CO92 uridine kinase YP_002346540.1 1732829 D 214092 CDS YP_002346541.1 218928666 1174364 1733575..1734156 1 NC_003143.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 1734156 dcd 1174364 dcd Yersinia pestis CO92 deoxycytidine triphosphate deaminase YP_002346541.1 1733575 D 214092 CDS YP_002346542.1 218928667 1174365 1734343..1736199 1 NC_003143.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein 1736199 1174365 YPO1526 Yersinia pestis CO92 assembly protein YP_002346542.1 1734343 D 214092 CDS YP_002346543.1 218928668 1174366 complement(1736344..1737930) 1 NC_003143.1 hypothetical protein 1737930 1174366 YPO1527 Yersinia pestis CO92 hypothetical protein YP_002346543.1 1736344 R 214092 CDS YP_002346544.1 218928669 1174367 1738372..1739151 1 NC_003143.1 ferric iron reductase involved in ferric hydroximate transport 1739151 1174367 YPO1528 Yersinia pestis CO92 ferric iron reductase involved in ferric hydroximate transport YP_002346544.1 1738372 D 214092 CDS YP_002346545.1 218928670 1174368 1739303..1740850 1 NC_003143.1 decarboxylase 1740850 1174368 YPO1529 Yersinia pestis CO92 decarboxylase YP_002346545.1 1739303 D 214092 CDS YP_002346546.1 218928671 1174369 1740885..1742183 1 NC_003143.1 siderophore biosynthetic enzyme 1742183 alcA 1174369 alcA Yersinia pestis CO92 siderophore biosynthetic enzyme YP_002346546.1 1740885 D 214092 CDS YP_002346547.1 218928672 1174370 1742180..1742761 1 NC_003143.1 siderophore biosynthetic enzyme 1742761 alcB 1174370 alcB Yersinia pestis CO92 siderophore biosynthetic enzyme YP_002346547.1 1742180 D 214092 CDS YP_002346548.1 218928673 1174371 1742758..1744602 1 NC_003143.1 siderophore biosynthetic enzyme 1744602 1174371 YPO1532 Yersinia pestis CO92 siderophore biosynthetic enzyme YP_002346548.1 1742758 D 214092 CDS YP_002346549.1 218928674 1174372 complement(1744711..1745559) 1 NC_003143.1 iron-siderophore transporter ATP-binding protein 1745559 1174372 YPO1533 Yersinia pestis CO92 iron-siderophore transporter ATP-binding protein YP_002346549.1 1744711 R 214092 CDS YP_002346550.1 218928675 1174373 complement(1745556..1746596) 1 NC_003143.1 iron-siderophore transporter membrane permease 1746596 1174373 YPO1534 Yersinia pestis CO92 iron-siderophore transporter membrane permease YP_002346550.1 1745556 R 214092 CDS YP_002346551.1 218928676 1174374 complement(1746583..1747623) 1 NC_003143.1 iron-siderophore transporter transmembrane protein 1747623 1174374 YPO1535 Yersinia pestis CO92 iron-siderophore transporter transmembrane protein YP_002346551.1 1746583 R 214092 CDS YP_002346552.1 218928677 1174375 complement(1747620..1748699) 1 NC_003143.1 iron-siderophore transporter substrate-binding protein 1748699 1174375 YPO1536 Yersinia pestis CO92 iron-siderophore transporter substrate-binding protein YP_002346552.1 1747620 R 214092 CDS YP_002346553.1 218928678 1174376 complement(1748789..1751050) 1 NC_003143.1 iron-siderophore receptor 1751050 1174376 YPO1537 Yersinia pestis CO92 iron-siderophore receptor YP_002346553.1 1748789 R 214092 CDS YP_002346554.1 218928679 1174377 complement(1751263..1753077) 1 NC_003143.1 siderophore biosynthetic enzyme 1753077 1174377 YPO1538 Yersinia pestis CO92 siderophore biosynthetic enzyme YP_002346554.1 1751263 R 214092 CDS YP_002346555.1 218928680 1174378 1754023..1754913 1 NC_003143.1 UTP-glucose-1-phosphate uridylyltransferase 1754913 galU 1174378 galU Yersinia pestis CO92 UTP-glucose-1-phosphate uridylyltransferase YP_002346555.1 1754023 D 214092 CDS YP_002346556.1 218928681 1174379 1754997..1755890 1 NC_003143.1 UTP-glucose-1-phosphate uridylyltransferase 1755890 galF 1174379 galF Yersinia pestis CO92 UTP-glucose-1-phosphate uridylyltransferase YP_002346556.1 1754997 D 214092 CDS YP_002346557.1 218928682 1174380 1756276..1757685 1 NC_003143.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 1757685 gnd 1174380 gnd Yersinia pestis CO92 6-phosphogluconate dehydrogenase YP_002346557.1 1756276 D 214092 CDS YP_002346558.1 218928683 1174381 complement(1757885..1758499) 1 NC_003143.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 1758499 hisI 1174381 hisI Yersinia pestis CO92 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_002346558.1 1757885 R 214092 CDS YP_002346559.1 218928684 1174382 complement(1758493..1759269) 1 NC_003143.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 1759269 hisF 1174382 hisF Yersinia pestis CO92 imidazole glycerol phosphate synthase subunit HisF YP_002346559.1 1758493 R 214092 CDS YP_002346560.1 218928685 1174383 complement(1759251..1759988) 1 NC_003143.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 1759988 hisA 1174383 hisA Yersinia pestis CO92 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_002346560.1 1759251 R 214092 CDS YP_002346561.1 218928686 1174384 complement(1759994..1760584) 1 NC_003143.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 1760584 hisH 1174384 hisH Yersinia pestis CO92 imidazole glycerol phosphate synthase subunit HisH YP_002346561.1 1759994 R 214092 CDS YP_002346562.1 218928687 1174385 complement(1760584..1761651) 1 NC_003143.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 1761651 hisB 1174385 hisB Yersinia pestis CO92 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_002346562.1 1760584 R 214092 CDS YP_002346563.1 218928688 1174386 complement(1761648..1762796) 1 NC_003143.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1762796 hisC 1174386 hisC Yersinia pestis CO92 histidinol-phosphate aminotransferase YP_002346563.1 1761648 R 214092 CDS YP_002346564.1 218928689 1174387 complement(1762799..1764130) 1 NC_003143.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 1764130 hisD 1174387 hisD Yersinia pestis CO92 histidinol dehydrogenase YP_002346564.1 1762799 R 214092 CDS YP_002346565.1 218928690 1174388 complement(1764134..1765033) 1 NC_003143.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 1765033 hisG 1174388 hisG Yersinia pestis CO92 ATP phosphoribosyltransferase YP_002346565.1 1764134 R 214092 CDS YP_002346567.1 218928692 1174390 1765739..1766566 1 NC_003143.1 hypothetical protein 1766566 1174390 YPO1551 Yersinia pestis CO92 hypothetical protein YP_002346567.1 1765739 D 214092 CDS YP_002346568.1 218928693 1174391 complement(1766721..1767155) 1 NC_003143.1 Doubtful CDS with no significant database hits. The N-terminal region is similar to a repeat region which is found scattered throughout the genome; hypothetical protein 1767155 1174391 YPO1552 Yersinia pestis CO92 hypothetical protein YP_002346568.1 1766721 R 214092 CDS YP_002346569.1 218928694 1174392 complement(1767400..1768395) 1 NC_003143.1 ribose transporter permease 1768395 1174392 YPO1553 Yersinia pestis CO92 ribose transporter permease YP_002346569.1 1767400 R 214092 CDS YP_002346570.1 218928695 1174394 1770218..1771309 1 NC_003143.1 member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 1771309 1174394 YPO1556 Yersinia pestis CO92 hypothetical protein YP_002346570.1 1770218 D 214092 CDS YP_002346571.1 218928696 1174395 1771769..1773160 1 NC_003143.1 amino acid permease 1773160 yeeF 1174395 yeeF Yersinia pestis CO92 amino acid permease YP_002346571.1 1771769 D 214092 CDS YP_002346572.1 218928697 1174396 complement(1773897..1775327) 1 NC_003143.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 1775327 sbcB 1174396 sbcB Yersinia pestis CO92 exonuclease I YP_002346572.1 1773897 R 214092 CDS YP_002346573.1 218928698 1174397 1775590..1776729 1 NC_003143.1 hypothetical protein 1776729 1174397 YPO1559 Yersinia pestis CO92 hypothetical protein YP_002346573.1 1775590 D 214092 CDS YP_002346574.1 218928699 1174398 1777163..1777480 1 NC_003143.1 hypothetical protein 1777480 1174398 YPO1560 Yersinia pestis CO92 hypothetical protein YP_002346574.1 1777163 D 214092 CDS YP_002346575.1 218928700 1174400 1777851..1779059 1 NC_003143.1 transposase for the IS285 insertion element 1779059 y1062 1174400 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002346575.1 1777851 D 214092 CDS YP_008479701.1 537470162 1174399 complement(1779022..1782174) 1 NC_003143.1 hypothetical protein 1782174 1174399 YPO1562 Yersinia pestis CO92 hypothetical protein YP_008479701.1 1779022 R 214092 CDS YP_002346576.1 218928701 1174401 1783103..1784503 1 NC_003143.1 transmembrane transporter 1784503 1174401 YPO1563 Yersinia pestis CO92 transmembrane transporter YP_002346576.1 1783103 D 214092 CDS YP_002346577.1 218928702 1174402 complement(1784512..1784937) 1 NC_003143.1 hypothetical protein 1784937 1174402 YPO1564 Yersinia pestis CO92 hypothetical protein YP_002346577.1 1784512 R 214092 CDS YP_002346578.1 218928703 1174403 1785362..1786102 1 NC_003143.1 oxidoreductase 1786102 1174403 YPO1565 Yersinia pestis CO92 oxidoreductase YP_002346578.1 1785362 D 214092 CDS YP_002346579.1 218928704 1174404 1786150..1786992 1 NC_003143.1 hydrolase 1786992 1174404 YPO1566 Yersinia pestis CO92 hydrolase YP_002346579.1 1786150 D 214092 CDS YP_002346580.2 284987068 1174405 1787024..1788301 1 NC_003143.1 racemase 1788301 1174405 YPO1567 Yersinia pestis CO92 racemase YP_002346580.2 1787024 D 214092 CDS YP_002346581.1 218928706 1174406 1788380..1788553 1 NC_003143.1 No significant database hits; hypothetical protein 1788553 1174406 YPO1568 Yersinia pestis CO92 hypothetical protein YP_002346581.1 1788380 D 214092 CDS YP_002346582.1 218928707 1174407 1788598..1789743 1 NC_003143.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 1789743 lldD 1174407 lldD Yersinia pestis CO92 L-lactate dehydrogenase YP_002346582.1 1788598 D 214092 CDS YP_002346583.1 218928708 1174408 complement(1789948..1791315) 1 NC_003143.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 1791315 argG 1174408 argG Yersinia pestis CO92 argininosuccinate synthase YP_002346583.1 1789948 R 214092 CDS YP_002346584.1 218928709 1174409 1791609..1793039 1 NC_003143.1 hypothetical protein 1793039 yeeO 1174409 yeeO Yersinia pestis CO92 hypothetical protein YP_002346584.1 1791609 D 214092 CDS YP_002346585.1 218928710 1174410 complement(1793067..1794407) 1 NC_003143.1 sugar transporter 1794407 1174410 YPO1572 Yersinia pestis CO92 sugar transporter YP_002346585.1 1793067 R 214092 CDS YP_002346586.1 218928711 1174411 complement(1794443..1795351) 1 NC_003143.1 polysaccharide deacetylase 1795351 1174411 YPO1573 Yersinia pestis CO92 polysaccharide deacetylase YP_002346586.1 1794443 R 214092 CDS YP_002346587.1 218928712 1174412 1795901..1796596 1 NC_003143.1 hypothetical protein 1796596 1174412 YPO1574 Yersinia pestis CO92 hypothetical protein YP_002346587.1 1795901 D 214092 CDS YP_002346588.1 218928713 1174413 1796713..1797225 1 NC_003143.1 hypothetical protein 1797225 1174413 YPO1575 Yersinia pestis CO92 hypothetical protein YP_002346588.1 1796713 D 214092 CDS YP_002346589.1 218928714 1174415 complement(1798092..1798721) 1 NC_003143.1 GerR family transcriptional regulator 1798721 1174415 YPO1576 Yersinia pestis CO92 GerR family transcriptional regulator YP_002346589.1 1798092 R 214092 CDS YP_002346590.1 218928715 1174416 complement(1798979..1800271) 1 NC_003143.1 C4-dicarboxylate transporter large subunit 1800271 1174416 YPO1577 Yersinia pestis CO92 C4-dicarboxylate transporter large subunit YP_002346590.1 1798979 R 214092 CDS YP_002346591.1 218928716 1174417 complement(1800291..1800797) 1 NC_003143.1 C4-dicarboxylate transporter small subunit 1800797 1174417 YPO1578 Yersinia pestis CO92 C4-dicarboxylate transporter small subunit YP_002346591.1 1800291 R 214092 CDS YP_002346592.1 218928717 1174418 complement(1800921..1801913) 1 NC_003143.1 C4-dicarboxylate transporter substrate-binding protein 1801913 1174418 YPO1579 Yersinia pestis CO92 C4-dicarboxylate transporter substrate-binding protein YP_002346592.1 1800921 R 214092 CDS YP_002346593.1 218928718 1174419 1802436..1803176 1 NC_003143.1 phosphopantetheinyl transferase 1803176 1174419 YPO1580 Yersinia pestis CO92 phosphopantetheinyl transferase YP_002346593.1 1802436 D 214092 CDS YP_008479702.1 537470163 16744754 complement(1803382..1803546) 1 NC_003143.1 hypothetical protein 1803546 16744754 YPO1580a Yersinia pestis CO92 hypothetical protein YP_008479702.1 1803382 R 214092 CDS YP_002346594.1 218928719 1174420 complement(1803563..1805689) 1 NC_003143.1 alpha-galactosidase 1805689 rafA 1174420 rafA Yersinia pestis CO92 alpha-galactosidase YP_002346594.1 1803563 R 214092 CDS YP_008479703.1 537470164 1174421 complement(1805767..1807011) 1 NC_003143.1 galactoside permease 1807011 1174421 YPO1582 Yersinia pestis CO92 galactoside permease YP_008479703.1 1805767 R 214092 CDS YP_002346595.1 218928720 1174422 1807069..1808277 1 NC_003143.1 transposase for the IS285 insertion element 1808277 y1062 1174422 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002346595.1 1807069 D 214092 CDS YP_008479704.1 537470165 16744755 complement(1808240..1808536) 1 NC_003143.1 biofilm formation regulatory protein BssS 1808536 16744755 YPO1583a Yersinia pestis CO92 biofilm formation regulatory protein BssS YP_008479704.1 1808240 R 214092 CDS YP_002346596.1 218928721 1174424 1808703..1808843 1 NC_003143.1 No significant database hits; hypothetical protein 1808843 1174424 YPO1585 Yersinia pestis CO92 hypothetical protein YP_002346596.1 1808703 D 214092 CDS YP_002346597.1 218928722 1174425 complement(1809042..1809287) 1 NC_003143.1 DNA damage-inducible protein I 1809287 dinI 1174425 dinI Yersinia pestis CO92 DNA damage-inducible protein I YP_002346597.1 1809042 R 214092 CDS YP_002346598.1 218928723 1174426 complement(1809600..1810646) 1 NC_003143.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1810646 pyrC 1174426 pyrC Yersinia pestis CO92 dihydroorotase YP_002346598.1 1809600 R 214092 CDS YP_002346599.1 218928724 1174427 1810881..1811168 1 NC_003143.1 hypothetical protein 1811168 1174427 YPO1588 Yersinia pestis CO92 hypothetical protein YP_002346599.1 1810881 D 214092 CDS YP_002346600.1 218928725 1174428 complement(1811445..1812653) 1 NC_003143.1 transposase for the IS285 insertion element 1812653 y1062 1174428 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002346600.1 1811445 R 214092 CDS YP_002346601.1 218928726 1174429 complement(1812749..1816414) 1 NC_003143.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1816414 rne 1174429 rne Yersinia pestis CO92 ribonuclease E YP_002346601.1 1812749 R 214092 CDS YP_002346602.1 218928727 1174430 1816989..1817951 1 NC_003143.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1817951 rluC 1174430 rluC Yersinia pestis CO92 23S rRNA pseudouridylate synthase C YP_002346602.1 1816989 D 214092 CDS YP_002346603.1 218928728 1174431 1818171..1818629 1 NC_003143.1 transposase for the IS1541 insertion element 1818629 tnp 1174431 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346603.1 1818171 D 214092 CDS YP_002346604.1 218928729 1174432 complement(1818784..1819380) 1 NC_003143.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1819380 maf 1174432 maf Yersinia pestis CO92 Maf-like protein YP_002346604.1 1818784 R 214092 CDS YP_002346605.1 218928730 1174433 1819522..1820046 1 NC_003143.1 hypothetical protein 1820046 1174433 YPO1594 Yersinia pestis CO92 hypothetical protein YP_002346605.1 1819522 D 214092 CDS YP_002346606.1 218928731 1174434 1820059..1820226 1 NC_003143.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1820226 rpmF 1174434 rpmF Yersinia pestis CO92 50S ribosomal protein L32 YP_002346606.1 1820059 D 214092 CDS YP_002346607.1 218928732 1174435 1820260..1821294 1 NC_003143.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1821294 plsX 1174435 plsX Yersinia pestis CO92 glycerol-3-phosphate acyltransferase PlsX YP_002346607.1 1820260 D 214092 CDS YP_002346608.1 218928733 1174436 1821301..1822251 1 NC_003143.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1822251 fabH 1174436 fabH Yersinia pestis CO92 3-oxoacyl-ACP synthase YP_002346608.1 1821301 D 214092 CDS YP_002346609.1 218928734 1174437 1822289..1823218 1 NC_003143.1 malonyl CoA-ACP transacylase 1823218 fabD 1174437 fabD Yersinia pestis CO92 malonyl CoA-ACP transacylase YP_002346609.1 1822289 D 214092 CDS YP_002346610.1 218928735 1174438 1823232..1823966 1 NC_003143.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1823966 fabG 1174438 fabG Yersinia pestis CO92 3-ketoacyl-ACP reductase YP_002346610.1 1823232 D 214092 CDS YP_002346611.1 218928736 1174439 1824120..1824356 1 NC_003143.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1824356 acpP 1174439 acpP Yersinia pestis CO92 acyl carrier protein YP_002346611.1 1824120 D 214092 CDS YP_002346612.1 218928737 1174440 1824451..1825692 1 NC_003143.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 1825692 fabF 1174440 fabF Yersinia pestis CO92 3-oxoacyl-ACP synthase YP_002346612.1 1824451 D 214092 CDS YP_002346613.1 218928738 1174441 1825892..1826350 1 NC_003143.1 transposase for the IS1541 insertion element 1826350 tnp 1174441 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346613.1 1825892 D 214092 CDS YP_002346614.1 218928739 1174442 1826766..1827572 1 NC_003143.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; 4-amino-4-deoxychorismate lyase 1827572 pabC 1174442 pabC Yersinia pestis CO92 4-amino-4-deoxychorismate lyase YP_002346614.1 1826766 D 214092 CDS YP_002346615.1 218928740 1174443 1827861..1828886 1 NC_003143.1 hypothetical protein 1828886 yceG 1174443 yceG Yersinia pestis CO92 hypothetical protein YP_002346615.1 1827861 D 214092 CDS YP_002346616.1 218928741 1174444 1828876..1829514 1 NC_003143.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1829514 tmk 1174444 tmk Yersinia pestis CO92 thymidylate kinase YP_002346616.1 1828876 D 214092 CDS YP_002346617.1 218928742 1174445 1829514..1830536 1 NC_003143.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1830536 holB 1174445 holB Yersinia pestis CO92 DNA polymerase III subunit delta' YP_002346617.1 1829514 D 214092 CDS YP_002346618.1 218928743 1174446 1830551..1831360 1 NC_003143.1 metallodependent hydrolase 1831360 1174446 YPO1607 Yersinia pestis CO92 metallodependent hydrolase YP_002346618.1 1830551 D 214092 CDS YP_002346619.1 218928744 1174447 1831666..1833099 1 NC_003143.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunits IIBC 1833099 ptsG 1174447 ptsG Yersinia pestis CO92 PTS system glucose-specific transporter subunits IIBC YP_002346619.1 1831666 D 214092 CDS YP_002346620.1 218928745 1174448 1833289..1833747 1 NC_003143.1 transposase for the IS1541 insertion element 1833747 tnp 1174448 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346620.1 1833289 D 214092 CDS YP_002346621.1 218928746 1174449 1834190..1835008 1 NC_003143.1 catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1835008 aroE 1174449 aroE Yersinia pestis CO92 shikimate 5-dehydrogenase YP_002346621.1 1834190 D 214092 CDS YP_002346622.1 218928747 1174450 1835182..1835535 1 NC_003143.1 purine nucleoside phosphoramidase 1835535 1174450 YPO1611 Yersinia pestis CO92 purine nucleoside phosphoramidase YP_002346622.1 1835182 D 214092 CDS YP_002346623.1 218928748 1174451 1835570..1835959 1 NC_003143.1 lipoprotein 1835959 ycfL 1174451 ycfL Yersinia pestis CO92 lipoprotein YP_002346623.1 1835570 D 214092 CDS YP_002346624.1 218928749 1174452 1836000..1836575 1 NC_003143.1 lipoprotein 1836575 1174452 YPO1613 Yersinia pestis CO92 lipoprotein YP_002346624.1 1836000 D 214092 CDS YP_002346625.1 218928750 1174453 1836616..1837422 1 NC_003143.1 hypothetical protein 1837422 1174453 YPO1614 Yersinia pestis CO92 hypothetical protein YP_002346625.1 1836616 D 214092 CDS YP_002346626.1 218928751 1174454 1837493..1838524 1 NC_003143.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1838524 ycfO 1174454 ycfO Yersinia pestis CO92 beta-hexosaminidase YP_002346626.1 1837493 D 214092 CDS YP_002346627.1 218928752 1174455 1838652..1839194 1 NC_003143.1 hypothetical protein 1839194 1174455 YPO1616 Yersinia pestis CO92 hypothetical protein YP_002346627.1 1838652 D 214092 CDS YP_002346628.1 218928753 1174456 1839569..1840873 1 NC_003143.1 NADH dehydrogenase 1840873 ndh 1174456 ndh Yersinia pestis CO92 NADH dehydrogenase YP_002346628.1 1839569 D 214092 CDS YP_002346631.1 218928756 1174459 1841988..1842401 1 NC_003143.1 No significant database hits; hypothetical protein 1842401 1174459 YPO1620 Yersinia pestis CO92 hypothetical protein YP_002346631.1 1841988 D 214092 CDS YP_002346632.1 218928757 1174460 1842497..1843705 1 NC_003143.1 transposase for the IS285 insertion element 1843705 y1062 1174460 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002346632.1 1842497 D 214092 CDS YP_002346633.1 218928758 1174461 complement(1844089..1844871) 1 NC_003143.1 transposase/IS protein 1844871 1174461 YPO1622 Yersinia pestis CO92 transposase/IS protein YP_002346633.1 1844089 R 214092 CDS YP_002346634.1 218928759 1174462 complement(1844868..1845890) 1 NC_003143.1 transposase for insertion sequence IS100 1845890 y1093 1174462 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346634.1 1844868 R 214092 CDS YP_002346635.1 218928760 1174463 1845995..1846534 1 NC_003143.1 hypothetical protein 1846534 ycfJ 1174463 ycfJ Yersinia pestis CO92 hypothetical protein YP_002346635.1 1845995 D 214092 CDS YP_002346636.1 218928761 1174464 complement(1846773..1850219) 1 NC_003143.1 transcription-repair coupling factor 1850219 mfd 1174464 mfd Yersinia pestis CO92 transcription-repair coupling factor YP_002346636.1 1846773 R 214092 CDS YP_002346637.1 218928762 1174465 1850489..1851691 1 NC_003143.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1851691 lolC 1174465 lolC Yersinia pestis CO92 outer membrane-specific lipoprotein transporter subunit LolC YP_002346637.1 1850489 D 214092 CDS YP_002346638.1 218928763 1174466 1851684..1852388 1 NC_003143.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding protein 1852388 lolD 1174466 lolD Yersinia pestis CO92 lipoprotein transporter ATP-binding protein YP_002346638.1 1851684 D 214092 CDS YP_002346639.1 218928764 1174467 1852385..1853635 1 NC_003143.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1853635 lolE 1174467 lolE Yersinia pestis CO92 outer membrane-specific lipoprotein transporter subunit LolE YP_002346639.1 1852385 D 214092 CDS YP_002346640.1 218928765 1174468 1853654..1854424 1 NC_003143.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1854424 1174468 YPO1629 Yersinia pestis CO92 N-acetyl-D-glucosamine kinase YP_002346640.1 1853654 D 214092 CDS YP_002346641.1 218928766 1174469 1854618..1855454 1 NC_003143.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1855454 cobB 1174469 cobB Yersinia pestis CO92 NAD-dependent deacetylase YP_002346641.1 1854618 D 214092 CDS YP_002346642.1 218928767 1174470 1855784..1857019 1 NC_003143.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1857019 pepT 1174470 pepT Yersinia pestis CO92 peptidase T YP_002346642.1 1855784 D 214092 CDS YP_002346643.1 218928768 1174471 complement(1857252..1858373) 1 NC_003143.1 hypothetical protein 1858373 1174471 YPO1632 Yersinia pestis CO92 hypothetical protein YP_002346643.1 1857252 R 214092 CDS YP_002346644.1 218928769 1174472 complement(1858457..1859911) 1 NC_003143.1 sensor protein PhoQ 1859911 phoQ 1174472 phoQ Yersinia pestis CO92 sensor protein PhoQ YP_002346644.1 1858457 R 214092 CDS YP_002346645.1 218928770 1174473 complement(1859917..1860588) 1 NC_003143.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1860588 phoP 1174473 phoP Yersinia pestis CO92 DNA-binding transcriptional regulator PhoP YP_002346645.1 1859917 R 214092 CDS YP_002346646.1 218928771 1174474 complement(1860799..1861422) 1 NC_003143.1 lipoprotein 1861422 1174474 YPO1635 Yersinia pestis CO92 lipoprotein YP_002346646.1 1860799 R 214092 CDS YP_002346647.1 218928772 1174475 complement(1861610..1862980) 1 NC_003143.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1862980 purB 1174475 purB Yersinia pestis CO92 adenylosuccinate lyase YP_002346647.1 1861610 R 214092 CDS YP_002346648.1 218928773 1174476 complement(1863041..1863667) 1 NC_003143.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1863667 1174476 YPO1637 Yersinia pestis CO92 hypothetical protein YP_002346648.1 1863041 R 214092 CDS YP_002346649.1 218928774 1174477 complement(1863725..1864840) 1 NC_003143.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1864840 mnmA 1174477 mnmA Yersinia pestis CO92 tRNA-specific 2-thiouridylase MnmA YP_002346649.1 1863725 R 214092 CDS YP_002346650.1 218928775 1174478 complement(1865027..1865473) 1 NC_003143.1 hypothetical protein 1865473 1174478 YPO1639 Yersinia pestis CO92 hypothetical protein YP_002346650.1 1865027 R 214092 CDS YP_002346651.1 218928776 1174479 complement(1865466..1866092) 1 NC_003143.1 pseudouridine synthase 1866092 ymfC 1174479 ymfC Yersinia pestis CO92 pseudouridine synthase YP_002346651.1 1865466 R 214092 CDS YP_002346652.1 218928777 1174480 1866223..1867476 1 NC_003143.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1867476 icdA 1174480 icdA Yersinia pestis CO92 isocitrate dehydrogenase YP_002346652.1 1866223 D 214092 CDS YP_002346653.1 218928778 1174481 complement(1867622..1868665) 1 NC_003143.1 sucrose operon repressor LacI family 1868665 cscR 1174481 cscR Yersinia pestis CO92 sucrose operon repressor LacI family YP_002346653.1 1867622 R 214092 CDS YP_002346654.1 218928779 1174482 complement(1868941..1869201) 1 NC_003143.1 No significant database hits; hypothetical protein 1869201 1174482 YPO1643 Yersinia pestis CO92 hypothetical protein YP_002346654.1 1868941 R 214092 CDS YP_002346655.1 218928780 1174483 complement(1869321..1870901) 1 NC_003143.1 methyl-accepting chemotaxis protein 1870901 aer 1174483 aer Yersinia pestis CO92 methyl-accepting chemotaxis protein YP_002346655.1 1869321 R 214092 CDS YP_002346656.1 218928781 1174484 complement(1871821..1872678) 1 NC_003143.1 hypothetical protein 1872678 1174484 YPO1645 Yersinia pestis CO92 hypothetical protein YP_002346656.1 1871821 R 214092 CDS YP_002346657.1 218928782 1174485 1872838..1873221 1 NC_003143.1 hypothetical protein 1873221 1174485 YPO1646 Yersinia pestis CO92 hypothetical protein YP_002346657.1 1872838 D 214092 CDS YP_002346658.1 218928783 1174487 1873753..1875078 1 NC_003143.1 phosphoanhydride phosphorylase 1875078 1174487 YPO1648 Yersinia pestis CO92 phosphoanhydride phosphorylase YP_002346658.1 1873753 D 214092 CDS YP_002346659.1 218928784 1174488 complement(1875380..1875595) 1 NC_003143.1 hypothetical protein 1875595 1174488 YPO1649 Yersinia pestis CO92 hypothetical protein YP_002346659.1 1875380 R 214092 CDS YP_002346660.1 218928785 1174489 complement(1875886..1876788) 1 NC_003143.1 hypothetical protein 1876788 1174489 YPO1650 Yersinia pestis CO92 hypothetical protein YP_002346660.1 1875886 R 214092 CDS YP_002346661.1 218928786 1174490 complement(1876877..1877326) 1 NC_003143.1 AsnC family transcriptional regulator 1877326 1174490 YPO1651 Yersinia pestis CO92 AsnC family transcriptional regulator YP_002346661.1 1876877 R 214092 CDS YP_002346662.1 218928787 1174491 complement(1877817..1878350) 1 NC_003143.1 hypothetical protein 1878350 ylaC 1174491 ylaC Yersinia pestis CO92 hypothetical protein YP_002346662.1 1877817 R 214092 CDS YP_002346663.1 218928788 1174492 complement(1878633..1879643) 1 NC_003143.1 zinc-binding dehydrogenase 1879643 1174492 YPO1653 Yersinia pestis CO92 zinc-binding dehydrogenase YP_002346663.1 1878633 R 214092 CDS YP_002346664.1 218928789 1174493 complement(1880050..1883232) 1 NC_003143.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 1883232 lacZ 1174493 lacZ Yersinia pestis CO92 beta-D-galactosidase YP_002346664.1 1880050 R 214092 CDS YP_002346665.1 218928790 1174494 1883773..1883985 1 NC_003143.1 cold shock protein 1883985 cspC 1174494 cspC Yersinia pestis CO92 cold shock protein YP_002346665.1 1883773 D 214092 CDS YP_002346666.1 218928791 1174495 1884200..1884391 1 NC_003143.1 hypothetical protein 1884391 1174495 YPO1656 Yersinia pestis CO92 hypothetical protein YP_002346666.1 1884200 D 214092 CDS YP_002346668.1 218928793 1174499 1887422..1888132 1 NC_003143.1 Mg(2+) transport ATPase protein C 1888132 mgtC 1174499 mgtC Yersinia pestis CO92 Mg(2+) transport ATPase protein C YP_002346668.1 1887422 D 214092 CDS YP_002346669.1 218928794 1174500 1888533..1891232 1 NC_003143.1 Mg(2+) transport ATPase protein B 1891232 mgtB 1174500 mgtB Yersinia pestis CO92 Mg(2+) transport ATPase protein B YP_002346669.1 1888533 D 214092 CDS YP_002346670.1 218928795 1174502 1892772..1893356 1 NC_003143.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 1893356 flhC 1174502 flhC Yersinia pestis CO92 transcriptional activator FlhC YP_002346670.1 1892772 D 214092 CDS YP_002346671.1 218928796 1174503 1893561..1894448 1 NC_003143.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 1894448 motA 1174503 motA Yersinia pestis CO92 flagellar motor protein MotA YP_002346671.1 1893561 D 214092 CDS YP_002346672.1 218928797 1174504 1894445..1895728 1 NC_003143.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1895728 motB 1174504 motB Yersinia pestis CO92 flagellar motor protein MotB YP_002346672.1 1894445 D 214092 CDS YP_002346673.1 218928798 1174505 1895739..1897910 1 NC_003143.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 1897910 cheA 1174505 cheA Yersinia pestis CO92 chemotaxis protein CheA YP_002346673.1 1895739 D 214092 CDS YP_002346674.1 218928799 1174506 1898073..1898570 1 NC_003143.1 purine-binding chemotaxis protein 1898570 cheW 1174506 cheW Yersinia pestis CO92 purine-binding chemotaxis protein YP_002346674.1 1898073 D 214092 CDS YP_002346675.1 218928800 1174507 complement(1898862..1900097) 1 NC_003143.1 hypothetical protein 1900097 yihN 1174507 yihN Yersinia pestis CO92 hypothetical protein YP_002346675.1 1898862 R 214092 CDS YP_002346676.1 218928801 1174508 complement(1900110..1900487) 1 NC_003143.1 hypothetical protein 1900487 1174508 YPO1669 Yersinia pestis CO92 hypothetical protein YP_002346676.1 1900110 R 214092 CDS YP_002346677.1 218928802 1174509 complement(1900484..1901470) 1 NC_003143.1 hypothetical protein 1901470 1174509 YPO1670 Yersinia pestis CO92 hypothetical protein YP_002346677.1 1900484 R 214092 CDS YP_002346678.1 218928803 1174510 1901648..1902325 1 NC_003143.1 DNA-binding protein 1902325 1174510 YPO1671 Yersinia pestis CO92 DNA-binding protein YP_002346678.1 1901648 D 214092 CDS YP_002346679.1 218928804 1174511 1902800..1906606 1 NC_003143.1 hypothetical protein 1906606 1174511 YPO1672 Yersinia pestis CO92 hypothetical protein YP_002346679.1 1902800 D 214092 CDS YP_002346680.1 218928805 1174512 1907134..1910010 1 NC_003143.1 hypothetical protein 1910010 1174512 YPO1673 Yersinia pestis CO92 hypothetical protein YP_002346680.1 1907134 D 214092 CDS YP_002346681.1 218928806 1174513 1910079..1910780 1 NC_003143.1 hypothetical protein 1910780 1174513 YPO1674 Yersinia pestis CO92 hypothetical protein YP_002346681.1 1910079 D 214092 CDS YP_002346682.1 218928807 1174514 1911021..1912694 1 NC_003143.1 methyl-accepting chemotaxis protein 1912694 cheD 1174514 cheD Yersinia pestis CO92 methyl-accepting chemotaxis protein YP_002346682.1 1911021 D 214092 CDS YP_002346683.1 218928808 1174516 1914661..1915533 1 NC_003143.1 methylates the MCP; chemotaxis methyltransferase CheR 1915533 cheR 1174516 cheR Yersinia pestis CO92 chemotaxis methyltransferase CheR YP_002346683.1 1914661 D 214092 CDS YP_002346684.1 218928809 1174517 1915533..1916582 1 NC_003143.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1916582 cheB 1174517 cheB Yersinia pestis CO92 chemotaxis-specific methylesterase YP_002346684.1 1915533 D 214092 CDS YP_002346685.1 218928810 1174518 1916683..1917072 1 NC_003143.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 1917072 cheY 1174518 cheY Yersinia pestis CO92 chemotaxis regulatory protein CheY YP_002346685.1 1916683 D 214092 CDS YP_002346686.1 218928811 1174519 1917082..1917726 1 NC_003143.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 1917726 cheZ 1174519 cheZ Yersinia pestis CO92 chemotaxis regulator CheZ YP_002346686.1 1917082 D 214092 CDS YP_002346687.1 218928812 1174520 complement(1918040..1918159) 1 NC_003143.1 hypothetical protein 1918159 1174520 YPO1682 Yersinia pestis CO92 hypothetical protein YP_002346687.1 1918040 R 214092 CDS YP_002346688.1 218928813 1174521 1918291..1919055 1 NC_003143.1 N-acetylmuramoyl-L-alanine amidase 1919055 1174521 YPO1683 Yersinia pestis CO92 N-acetylmuramoyl-L-alanine amidase YP_002346688.1 1918291 D 214092 CDS YP_008479705.1 537470166 1174522 1919412..1921622 1 NC_003143.1 surface protein 1921622 1174522 YPO1684 Yersinia pestis CO92 surface protein YP_008479705.1 1919412 D 214092 CDS YP_002346689.1 218928814 1174523 1922143..1923096 1 NC_003143.1 hypothetical protein 1923096 1174523 YPO1686 Yersinia pestis CO92 hypothetical protein YP_002346689.1 1922143 D 214092 CDS YP_002346690.1 218928815 1174524 complement(1923715..1924944) 1 NC_003143.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 1924944 alr 1174524 alr Yersinia pestis CO92 alanine racemase YP_002346690.1 1923715 R 214092 CDS YP_008479706.1 537470167 16744757 complement(1925346..1925540) 1 NC_003143.1 hypothetical protein 1925540 16744757 YPO1687a Yersinia pestis CO92 hypothetical protein YP_008479706.1 1925346 R 214092 CDS YP_002346691.1 218928816 1174525 1926119..1926367 1 NC_003143.1 No significant database hits; hypothetical protein 1926367 1174525 YPO1688 Yersinia pestis CO92 hypothetical protein YP_002346691.1 1926119 D 214092 CDS YP_002346692.1 218928817 1174526 1926760..1928016 1 NC_003143.1 lipoprotein 1928016 1174526 YPO1689 Yersinia pestis CO92 lipoprotein YP_002346692.1 1926760 D 214092 CDS YP_002346693.1 218928818 1174527 1928171..1928404 1 NC_003143.1 No significant database hits; hypothetical protein 1928404 1174527 YPO1690 Yersinia pestis CO92 hypothetical protein YP_002346693.1 1928171 D 214092 CDS YP_002346694.1 218928819 1174528 complement(1928939..1929721) 1 NC_003143.1 transposase/IS protein 1929721 1174528 YPO1691 Yersinia pestis CO92 transposase/IS protein YP_002346694.1 1928939 R 214092 CDS YP_002346695.1 218928820 1174529 complement(1929718..1930740) 1 NC_003143.1 transposase for insertion sequence IS100 1930740 y1093 1174529 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346695.1 1929718 R 214092 CDS YP_002346696.1 218928821 1174530 1931147..1931536 1 NC_003143.1 hypothetical protein 1931536 1174530 YPO1693 Yersinia pestis CO92 hypothetical protein YP_002346696.1 1931147 D 214092 CDS YP_002346697.1 218928822 1174531 complement(1931646..1931885) 1 NC_003143.1 hypothetical protein 1931885 1174531 YPO1694 Yersinia pestis CO92 hypothetical protein YP_002346697.1 1931646 R 214092 CDS YP_002346698.1 218928823 1174532 complement(1932093..1933082) 1 NC_003143.1 hypothetical protein 1933082 1174532 YPO1695 Yersinia pestis CO92 hypothetical protein YP_002346698.1 1932093 R 214092 CDS YP_002346699.1 218928824 1174533 complement(1933288..1935735) 1 NC_003143.1 outer membrane usher protein 1935735 1174533 YPO1696 Yersinia pestis CO92 outer membrane usher protein YP_002346699.1 1933288 R 214092 CDS YP_002346700.1 218928825 1174534 complement(1935923..1936675) 1 NC_003143.1 chaperone protein 1936675 1174534 YPO1697 Yersinia pestis CO92 chaperone protein YP_002346700.1 1935923 R 214092 CDS YP_002346701.1 218928826 1174535 complement(1936706..1937263) 1 NC_003143.1 hypothetical protein 1937263 1174535 YPO1698 Yersinia pestis CO92 hypothetical protein YP_002346701.1 1936706 R 214092 CDS YP_002346702.1 218928827 1174536 complement(1937284..1937814) 1 NC_003143.1 hypothetical protein 1937814 1174536 YPO1699 Yersinia pestis CO92 hypothetical protein YP_002346702.1 1937284 R 214092 CDS YP_002346703.1 218928828 1174537 complement(1937820..1938374) 1 NC_003143.1 hypothetical protein 1938374 1174537 YPO1700 Yersinia pestis CO92 hypothetical protein YP_002346703.1 1937820 R 214092 CDS YP_002346704.1 218928829 1174538 complement(1938853..1941504) 1 NC_003143.1 hypothetical protein 1941504 1174538 YPO1701 Yersinia pestis CO92 hypothetical protein YP_002346704.1 1938853 R 214092 CDS YP_002346705.1 218928830 1174539 complement(1941473..1942825) 1 NC_003143.1 hypothetical protein 1942825 yebS 1174539 yebS Yersinia pestis CO92 hypothetical protein YP_002346705.1 1941473 R 214092 CDS YP_002346706.1 218928831 1174540 1942952..1943449 1 NC_003143.1 hypothetical protein 1943449 1174540 YPO1703 Yersinia pestis CO92 hypothetical protein YP_002346706.1 1942952 D 214092 CDS YP_002346707.1 218928832 1174541 1943545..1944258 1 NC_003143.1 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 1944258 proQ 1174541 proQ Yersinia pestis CO92 solute/DNA competence effector YP_002346707.1 1943545 D 214092 CDS YP_002346708.1 218928833 1174542 1944278..1946350 1 NC_003143.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1946350 prc 1174542 prc Yersinia pestis CO92 carboxy-terminal protease YP_002346708.1 1944278 D 214092 CDS YP_002346709.1 218928834 1174543 1946824..1947705 1 NC_003143.1 metalloprotease; heat shock protein HtpX 1947705 htpX 1174543 htpX Yersinia pestis CO92 heat shock protein HtpX YP_002346709.1 1946824 D 214092 CDS YP_002346710.1 218928835 1174544 1948363..1948905 1 NC_003143.1 fimbrial protein 1948905 1174544 YPO1707 Yersinia pestis CO92 fimbrial protein YP_002346710.1 1948363 D 214092 CDS YP_002346711.1 218928836 1174545 1949058..1949837 1 NC_003143.1 chaperone protein 1949837 ecpD 1174545 ecpD Yersinia pestis CO92 chaperone protein YP_002346711.1 1949058 D 214092 CDS YP_002346712.1 218928837 1174546 1949919..1952531 1 NC_003143.1 outer membrane usher protein 1952531 htrE 1174546 htrE Yersinia pestis CO92 outer membrane usher protein YP_002346712.1 1949919 D 214092 CDS YP_002346713.1 218928838 1174547 1952528..1953691 1 NC_003143.1 fimbrial protein 1953691 1174547 YPO1710 Yersinia pestis CO92 fimbrial protein YP_002346713.1 1952528 D 214092 CDS YP_002346714.1 218928839 1174548 1953688..1954491 1 NC_003143.1 chaperone protein 1954491 1174548 YPO1711 Yersinia pestis CO92 chaperone protein YP_002346714.1 1953688 D 214092 CDS YP_002346715.1 218928840 1174549 complement(1954545..1955912) 1 NC_003143.1 transport protein 1955912 1174549 YPO1712 Yersinia pestis CO92 transport protein YP_002346715.1 1954545 R 214092 CDS YP_002346716.1 218928841 1174550 1956239..1957405 1 NC_003143.1 oligogalacturonate lyase 1957405 ogl 1174550 ogl Yersinia pestis CO92 oligogalacturonate lyase YP_002346716.1 1956239 D 214092 CDS YP_002346717.1 218928842 1174551 1957592..1958383 1 NC_003143.1 IclR family transcriptional regulator 1958383 kdgR 1174551 kdgR Yersinia pestis CO92 IclR family transcriptional regulator YP_002346717.1 1957592 D 214092 CDS YP_002346718.1 218928843 1174552 1958768..1959619 1 NC_003143.1 N-acetylmuramoyl-L-alanine amidase 1959619 1174552 YPO1715 Yersinia pestis CO92 N-acetylmuramoyl-L-alanine amidase YP_002346718.1 1958768 D 214092 CDS YP_002346719.1 218928844 1174553 complement(1959834..1961231) 1 NC_003143.1 transport protein 1961231 gltP 1174553 gltP Yersinia pestis CO92 transport protein YP_002346719.1 1959834 R 214092 CDS YP_002346720.1 218928845 1174554 complement(1961429..1961977) 1 NC_003143.1 hypothetical protein 1961977 ydjM 1174554 ydjM Yersinia pestis CO92 hypothetical protein YP_002346720.1 1961429 R 214092 CDS YP_002346721.1 218928846 1174555 complement(1962457..1963167) 1 NC_003143.1 hypothetical protein 1963167 1174555 YPO1718 Yersinia pestis CO92 hypothetical protein YP_002346721.1 1962457 R 214092 CDS YP_002346722.1 218928847 1174556 complement(1963465..1964757) 1 NC_003143.1 sugar-binding protein 1964757 1174556 YPO1719 Yersinia pestis CO92 sugar-binding protein YP_002346722.1 1963465 R 214092 CDS YP_002346723.1 218928848 1174557 complement(1964773..1965900) 1 NC_003143.1 sugar ABC transporter 1965900 1174557 YPO1720 Yersinia pestis CO92 sugar ABC transporter YP_002346723.1 1964773 R 214092 CDS YP_002346724.1 218928849 1174558 complement(1965914..1966834) 1 NC_003143.1 sugar ABC transporter (permease) 1966834 1174558 YPO1721 Yersinia pestis CO92 sugar ABC transporter (permease) YP_002346724.1 1965914 R 214092 CDS YP_002346725.1 218928850 1174559 complement(1966827..1967717) 1 NC_003143.1 sugar ABC transporter permease 1967717 1174559 YPO1722 Yersinia pestis CO92 sugar ABC transporter permease YP_002346725.1 1966827 R 214092 CDS YP_002346726.1 218928851 1174560 complement(1967758..1969425) 1 NC_003143.1 exopolygalacturonate lyase 1969425 kdgC 1174560 kdgC Yersinia pestis CO92 exopolygalacturonate lyase YP_002346726.1 1967758 R 214092 CDS YP_002346727.1 218928852 1174561 complement(1969761..1970522) 1 NC_003143.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate; 2-deoxy-D-gluconate 3-dehydrogenase 1970522 kduD1 1174561 kduD1 Yersinia pestis CO92 2-deoxy-D-gluconate 3-dehydrogenase YP_002346727.1 1969761 R 214092 CDS YP_002346728.1 218928853 1174562 complement(1970614..1971450) 1 NC_003143.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 5-keto-4-deoxyuronate isomerase 1971450 kduI 1174562 kduI Yersinia pestis CO92 5-keto-4-deoxyuronate isomerase YP_002346728.1 1970614 R 214092 CDS YP_002346729.1 218928854 1174564 1972184..1973392 1 NC_003143.1 transposase for the IS285 insertion element 1973392 y1062 1174564 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002346729.1 1972184 D 214092 CDS YP_002346730.1 218928855 1174566 1974768..1975790 1 NC_003143.1 transposase for insertion sequence IS100 1975790 y1093 1174566 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346730.1 1974768 D 214092 CDS YP_002346731.1 218928856 1174567 1975787..1976569 1 NC_003143.1 transposase/IS protein 1976569 1174567 YPO1730 Yersinia pestis CO92 transposase/IS protein YP_002346731.1 1975787 D 214092 CDS YP_002346732.1 218928857 1174569 complement(1977238..1978050) 1 NC_003143.1 hypothetical protein 1978050 1174569 YPO1732 Yersinia pestis CO92 hypothetical protein YP_002346732.1 1977238 R 214092 CDS YP_002346733.1 218928858 1174570 complement(1978440..1978724) 1 NC_003143.1 hypothetical protein 1978724 1174570 YPO1733 Yersinia pestis CO92 hypothetical protein YP_002346733.1 1978440 R 214092 CDS YP_002346734.1 218928859 1174571 complement(1978961..1979812) 1 NC_003143.1 hypothetical protein 1979812 1174571 YPO1734 Yersinia pestis CO92 hypothetical protein YP_002346734.1 1978961 R 214092 CDS YP_002346735.1 218928860 1174572 complement(1979915..1981633) 1 NC_003143.1 ABC transporter ATP-binding protein 1981633 1174572 YPO1735 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002346735.1 1979915 R 214092 CDS YP_002346736.1 218928861 1174573 1982289..1982453 1 NC_003143.1 hypothetical protein 1982453 1174573 YPO1736 Yersinia pestis CO92 hypothetical protein YP_002346736.1 1982289 D 214092 CDS YP_002346737.1 218928862 1174574 complement(1982535..1982921) 1 NC_003143.1 AraC family transcriptional regulator 1982921 1174574 YPO1737 Yersinia pestis CO92 AraC family transcriptional regulator YP_002346737.1 1982535 R 214092 CDS YP_002346738.1 218928863 1174575 1983477..1983716 1 NC_003143.1 hypothetical protein 1983716 1174575 YPO1738 Yersinia pestis CO92 hypothetical protein YP_002346738.1 1983477 D 214092 CDS YP_002346739.1 218928864 1174576 complement(1983807..1984025) 1 NC_003143.1 hypothetical protein 1984025 1174576 YPO1739 Yersinia pestis CO92 hypothetical protein YP_002346739.1 1983807 R 214092 CDS YP_002346740.1 218928865 1174577 1984623..1984898 1 NC_003143.1 hypothetical protein 1984898 1174577 YPO1740 Yersinia pestis CO92 hypothetical protein YP_002346740.1 1984623 D 214092 CDS YP_002346741.1 218928866 1174578 1985161..1985460 1 NC_003143.1 hypothetical protein 1985460 1174578 YPO1741 Yersinia pestis CO92 hypothetical protein YP_002346741.1 1985161 D 214092 CDS YP_002346742.2 559797714 1174579 1985569..1985814 1 NC_003143.1 hypothetical protein 1985814 1174579 YPO1742 Yersinia pestis CO92 hypothetical protein YP_002346742.2 1985569 D 214092 CDS YP_002346743.1 218928868 1174580 1986051..1987424 1 NC_003143.1 aromatic amino acid transport protein 1987424 aroP 1174580 aroP Yersinia pestis CO92 aromatic amino acid transport protein YP_002346743.1 1986051 D 214092 CDS YP_002346744.1 218928869 1174581 complement(1987729..1988328) 1 NC_003143.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 1988328 pagP 1174581 pagP Yersinia pestis CO92 palmitoyl transferase YP_002346744.1 1987729 R 214092 CDS YP_002346745.1 218928870 1174582 1989330..1989446 1 NC_003143.1 hypothetical protein 1989446 1174582 YPO1745 Yersinia pestis CO92 hypothetical protein YP_002346745.1 1989330 D 214092 CDS YP_002346746.1 218928871 1174583 1989489..1989698 1 NC_003143.1 cold shock-like protein CspC 1989698 cspC 1174583 cspC Yersinia pestis CO92 cold shock-like protein CspC YP_002346746.1 1989489 D 214092 CDS YP_002346747.1 218928872 1174584 complement(1989789..1990544) 1 NC_003143.1 hypothetical protein 1990544 1174584 YPO1747 Yersinia pestis CO92 hypothetical protein YP_002346747.1 1989789 R 214092 CDS YP_002346748.1 218928873 1174585 1990939..1991778 1 NC_003143.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth; 23S rRNA methyltransferase 1991778 rrmA 1174585 rrmA Yersinia pestis CO92 23S rRNA methyltransferase YP_002346748.1 1990939 D 214092 CDS YP_002346749.1 218928874 1174586 complement(1992000..1992278) 1 NC_003143.1 hypothetical protein 1992278 1174586 YPO1749 Yersinia pestis CO92 hypothetical protein YP_002346749.1 1992000 R 214092 CDS YP_002346750.1 218928875 1174588 1992646..1993668 1 NC_003143.1 transposase for insertion sequence IS100 1993668 y1093 1174588 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346750.1 1992646 D 214092 CDS YP_002346751.1 218928876 1174589 1993665..1994447 1 NC_003143.1 transposase/IS protein 1994447 1174589 YPO1751 Yersinia pestis CO92 transposase/IS protein YP_002346751.1 1993665 D 214092 CDS YP_008479707.1 537470168 16744759 complement(1994498..1996540) 1 NC_003143.1 PAS/PAC domain-containing protein 1996540 16744759 YPO1751a Yersinia pestis CO92 PAS/PAC domain-containing protein YP_008479707.1 1994498 R 214092 CDS YP_002346752.1 218928877 1174590 1996899..1999175 1 NC_003143.1 ferrichrome receptor protein 1999175 fcuA 1174590 fcuA Yersinia pestis CO92 ferrichrome receptor protein YP_002346752.1 1996899 D 214092 CDS YP_002346753.1 218928878 1174591 complement(1999336..1999905) 1 NC_003143.1 hypothetical protein 1999905 yebN 1174591 yebN Yersinia pestis CO92 hypothetical protein YP_002346753.1 1999336 R 214092 CDS YP_002346754.1 218928879 1174592 complement(2000334..2000795) 1 NC_003143.1 hypothetical protein 2000795 yobD 1174592 yobD Yersinia pestis CO92 hypothetical protein YP_002346754.1 2000334 R 214092 CDS YP_002346755.1 218928880 1174593 complement(2000995..2001882) 1 NC_003143.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 2001882 manZ 1174593 manZ Yersinia pestis CO92 PTS system mannose-specific transporter subunit IID YP_002346755.1 2000995 R 214092 CDS YP_002346756.1 218928881 1174594 complement(2001889..2002686) 1 NC_003143.1 PTS system mannose-specific transporter subunit C 2002686 manY 1174594 manY Yersinia pestis CO92 PTS system mannose-specific transporter subunit C YP_002346756.1 2001889 R 214092 CDS YP_002346757.1 218928882 1174595 complement(2002778..2003752) 1 NC_003143.1 PTS system mannose-specific transporter subunit IIAB 2003752 gptB 1174595 gptB Yersinia pestis CO92 PTS system mannose-specific transporter subunit IIAB YP_002346757.1 2002778 R 214092 CDS YP_002346759.1 218928884 1174597 complement(2006019..2006486) 1 NC_003143.1 homoprotocatechuate degradative operon repressor 2006486 hpaR 1174597 hpaR Yersinia pestis CO92 homoprotocatechuate degradative operon repressor YP_002346759.1 2006019 R 214092 CDS YP_008479708.1 537470169 1174598 2006870..2007502 1 NC_003143.1 fumarylacetoacetate hydrolase family 2007502 1174598 YPO1761 Yersinia pestis CO92 fumarylacetoacetate hydrolase family YP_008479708.1 2006870 D 214092 CDS YP_008479709.1 537470170 16744760 2007499..2008263 1 NC_003143.1 fumarylacetoacetate hydrolase family protein 2008263 16744760 YPO1761a Yersinia pestis CO92 fumarylacetoacetate hydrolase family protein YP_008479709.1 2007499 D 214092 CDS YP_002346760.1 218928885 1174599 2008260..2009657 1 NC_003143.1 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 2009657 hpaE 1174599 hpaE Yersinia pestis CO92 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase YP_002346760.1 2008260 D 214092 CDS YP_002346761.1 218928886 1174600 2009776..2010633 1 NC_003143.1 3,4-dihydroxyphenylacetate 2,3-dioxygenase 2010633 hpaD 1174600 hpaD Yersinia pestis CO92 3,4-dihydroxyphenylacetate 2,3-dioxygenase YP_002346761.1 2009776 D 214092 CDS YP_002346762.1 218928887 1174601 2010658..2011056 1 NC_003143.1 5-carboxymethyl-2-hydroxymuconate delta-isomerase 2011056 hpaF 1174601 hpaF Yersinia pestis CO92 5-carboxymethyl-2-hydroxymuconate delta-isomerase YP_002346762.1 2010658 D 214092 CDS YP_002346763.1 218928888 1174602 2011050..2011853 1 NC_003143.1 2-oxo-hept-3-ene-1,7-dioate hydratase 2011853 hpaH 1174602 hpaH Yersinia pestis CO92 2-oxo-hept-3-ene-1,7-dioate hydratase YP_002346763.1 2011050 D 214092 CDS YP_002346764.1 218928889 1174603 2011864..2012670 1 NC_003143.1 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 2012670 hpaI 1174603 hpaI Yersinia pestis CO92 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_002346764.1 2011864 D 214092 CDS YP_002346765.1 218928890 1174604 2012696..2014063 1 NC_003143.1 4-hydroxyphenylacetate permease 2014063 hpaX 1174604 hpaX Yersinia pestis CO92 4-hydroxyphenylacetate permease YP_002346765.1 2012696 D 214092 CDS YP_002346766.1 218928891 1174605 2014131..2015693 1 NC_003143.1 4-hydroxyphenylacetate 3-monooxygenase 2015693 hpaB 1174605 hpaB Yersinia pestis CO92 4-hydroxyphenylacetate 3-monooxygenase YP_002346766.1 2014131 D 214092 CDS YP_002346767.1 218928892 1174606 2015714..2016211 1 NC_003143.1 4-hydroxyphenylacetate 3-monooxygenase coupling protein 2016211 hpaC 1174606 hpaC Yersinia pestis CO92 4-hydroxyphenylacetate 3-monooxygenase coupling protein YP_002346767.1 2015714 D 214092 CDS YP_002346768.1 218928893 1174607 complement(2016491..2017855) 1 NC_003143.1 L-serine dehydratase 2017855 sdaA 1174607 sdaA Yersinia pestis CO92 L-serine dehydratase YP_002346768.1 2016491 R 214092 CDS YP_002346769.1 218928894 1174608 complement(2018563..2019162) 1 NC_003143.1 hypothetical protein 2019162 1174608 YPO1772 Yersinia pestis CO92 hypothetical protein YP_002346769.1 2018563 R 214092 CDS YP_002346770.1 218928895 1174609 complement(2019159..2020535) 1 NC_003143.1 para-aminobenzoate synthase component I 2020535 pabB 1174609 pabB Yersinia pestis CO92 para-aminobenzoate synthase component I YP_002346770.1 2019159 R 214092 CDS YP_002346771.1 218928896 1174610 2020700..2020957 1 NC_003143.1 hypothetical protein 2020957 1174610 YPO1774 Yersinia pestis CO92 hypothetical protein YP_002346771.1 2020700 D 214092 CDS YP_002346772.1 218928897 1174611 complement(2021083..2022264) 1 NC_003143.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 2022264 purT 1174611 purT Yersinia pestis CO92 phosphoribosylglycinamide formyltransferase 2 YP_002346772.1 2021083 R 214092 CDS YP_002346773.1 218928898 1174612 2022577..2023959 1 NC_003143.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 2023959 dbpA 1174612 dbpA Yersinia pestis CO92 ATP-dependent RNA helicase DbpA YP_002346773.1 2022577 D 214092 CDS YP_002346774.1 218928899 1174613 2024053..2024373 1 NC_003143.1 hypothetical protein 2024373 1174613 YPO1777 Yersinia pestis CO92 hypothetical protein YP_002346774.1 2024053 D 214092 CDS YP_002346775.1 218928900 1174614 2024413..2024721 1 NC_003143.1 hypothetical protein 2024721 1174614 YPO1778 Yersinia pestis CO92 hypothetical protein YP_002346775.1 2024413 D 214092 CDS YP_002346776.1 218928901 1174615 2024813..2025238 1 NC_003143.1 secreted protein; unknown function; hypothetical protein 2025238 1174615 YPO1779 Yersinia pestis CO92 hypothetical protein YP_002346776.1 2024813 D 214092 CDS YP_002346777.1 218928902 1174616 2025548..2027599 1 NC_003143.1 oligopeptidase B 2027599 ptrB 1174616 ptrB Yersinia pestis CO92 oligopeptidase B YP_002346777.1 2025548 D 214092 CDS YP_002346778.1 218928903 1174617 2028321..2029271 1 NC_003143.1 proline iminopeptidase 2029271 pip 1174617 pip Yersinia pestis CO92 proline iminopeptidase YP_002346778.1 2028321 D 214092 CDS YP_002346779.1 218928904 1174618 complement(2029331..2029561) 1 NC_003143.1 DNA polymerase III subunit theta 2029561 holE 1174618 holE Yersinia pestis CO92 DNA polymerase III subunit theta YP_002346779.1 2029331 R 214092 CDS YP_002346780.1 218928905 1174619 2029962..2030471 1 NC_003143.1 ferritin 2030471 ftn 1174619 ftn Yersinia pestis CO92 ferritin YP_002346780.1 2029962 D 214092 CDS YP_002346781.1 218928906 1174620 2030868..2031254 1 NC_003143.1 copper resistance protein 2031254 1174620 YPO1784 Yersinia pestis CO92 copper resistance protein YP_002346781.1 2030868 D 214092 CDS YP_002346782.1 218928907 1174621 2031257..2032141 1 NC_003143.1 copper resistance protein D 2032141 1174621 YPO1785 Yersinia pestis CO92 copper resistance protein D YP_002346782.1 2031257 D 214092 CDS YP_002346783.1 218928908 1174622 2032223..2032579 1 NC_003143.1 hypothetical protein 2032579 yebY 1174622 yebY Yersinia pestis CO92 hypothetical protein YP_002346783.1 2032223 D 214092 CDS YP_002346785.1 218928910 1174624 complement(2033102..2033428) 1 NC_003143.1 acyl carrier protein 2033428 1174624 YPO1788 Yersinia pestis CO92 acyl carrier protein YP_002346785.1 2033102 R 214092 CDS YP_002346786.1 218928911 1174625 complement(2033422..2033880) 1 NC_003143.1 hypothetical protein 2033880 1174625 YPO1789 Yersinia pestis CO92 hypothetical protein YP_002346786.1 2033422 R 214092 CDS YP_002346787.1 218928912 1174626 2034412..2035572 1 NC_003143.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; Yersinia has 2 copies of flhB; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar biosynthesis protein FlhB 2035572 flhB 1174626 flhB Yersinia pestis CO92 flagellar biosynthesis protein FlhB YP_002346787.1 2034412 D 214092 CDS YP_002346788.1 218928913 1174627 2035572..2037650 1 NC_003143.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 2037650 flhA 1174627 flhA Yersinia pestis CO92 flagellar biosynthesis protein FlhA YP_002346788.1 2035572 D 214092 CDS YP_002346789.1 218928914 1174628 2037650..2038072 1 NC_003143.1 flagellar protein FlhE 2038072 flhE 1174628 flhE Yersinia pestis CO92 flagellar protein FlhE YP_002346789.1 2037650 D 214092 CDS YP_002346790.1 218928915 1174630 2039730..2040188 1 NC_003143.1 transposase for the IS1541 insertion element 2040188 tnp 1174630 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002346790.1 2039730 D 214092 CDS YP_002346791.1 218928916 1174631 complement(2042540..2042980) 1 NC_003143.1 flagellar synthesis protein FlgN 2042980 flgN 1174631 flgN Yersinia pestis CO92 flagellar synthesis protein FlgN YP_002346791.1 2042540 R 214092 CDS YP_002346792.1 218928917 1174632 complement(2042999..2043301) 1 NC_003143.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma28 factor FlgM 2043301 flgM 1174632 flgM Yersinia pestis CO92 anti-sigma28 factor FlgM YP_002346792.1 2042999 R 214092 CDS YP_002346793.1 218928918 1174633 complement(2043452..2044150) 1 NC_003143.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 2044150 flgA 1174633 flgA Yersinia pestis CO92 flagellar basal body P-ring biosynthesis protein FlgA YP_002346793.1 2043452 R 214092 CDS YP_002346794.1 218928919 1174634 2044389..2044802 1 NC_003143.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal-body rod protein FlgB 2044802 flgB 1174634 flgB Yersinia pestis CO92 flagellar basal-body rod protein FlgB YP_002346794.1 2044389 D 214092 CDS YP_002346795.1 218928920 1174635 2044808..2045212 1 NC_003143.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 2045212 flgC 1174635 flgC Yersinia pestis CO92 flagellar basal body rod protein FlgC YP_002346795.1 2044808 D 214092 CDS YP_002346796.1 218928921 1174636 2045227..2045904 1 NC_003143.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 2045904 flgD 1174636 flgD Yersinia pestis CO92 flagellar basal body rod modification protein YP_002346796.1 2045227 D 214092 CDS YP_002346797.1 218928922 1174637 2046106..2047392 1 NC_003143.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 2047392 flgE 1174637 flgE Yersinia pestis CO92 flagellar hook protein FlgE YP_002346797.1 2046106 D 214092 CDS YP_002346798.1 218928923 1174638 2047414..2048043 1 NC_003143.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Yersinia contains two copies of this and other flagella genes; flagellar basal body rod protein FlgF 2048043 flgF 1174638 flgF Yersinia pestis CO92 flagellar basal body rod protein FlgF YP_002346798.1 2047414 D 214092 CDS YP_002346799.1 218928924 1174639 2048024..2048722 1 NC_003143.1 flagellar basal-body rod protein FlgG 2048722 1174639 YPO1804 Yersinia pestis CO92 flagellar basal-body rod protein FlgG YP_002346799.1 2048024 D 214092 CDS YP_002346800.1 218928925 1174640 2048866..2049555 1 NC_003143.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 2049555 flgH 1174640 flgH Yersinia pestis CO92 flagellar basal body L-ring protein YP_002346800.1 2048866 D 214092 CDS YP_002346801.1 218928926 1174641 2049570..2050679 1 NC_003143.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 2050679 flgI 1174641 flgI Yersinia pestis CO92 flagellar basal body P-ring biosynthesis protein FlgA YP_002346801.1 2049570 D 214092 CDS YP_002346802.1 218928927 1174642 2050679..2051623 1 NC_003143.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 2051623 flgJ 1174642 flgJ Yersinia pestis CO92 flagellar rod assembly protein/muramidase FlgJ YP_002346802.1 2050679 D 214092 CDS YP_002346803.1 218928928 1174643 2052494..2054158 1 NC_003143.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 2054158 flgK 1174643 flgK Yersinia pestis CO92 flagellar hook-associated protein FlgK YP_002346803.1 2052494 D 214092 CDS YP_002346804.1 218928929 1174644 2054264..2055277 1 NC_003143.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 2055277 flgL 1174644 flgL Yersinia pestis CO92 flagellar hook-associated protein FlgL YP_002346804.1 2054264 D 214092 CDS YP_002346805.1 218928930 1174645 complement(2055306..2056283) 1 NC_003143.1 transcriptional regulator 2056283 1174645 YPO1810 Yersinia pestis CO92 transcriptional regulator YP_002346805.1 2055306 R 214092 CDS YP_002346806.1 218928931 1174646 2056525..2058591 1 NC_003143.1 short chain dehydrogenase 2058591 1174646 YPO1811 Yersinia pestis CO92 short chain dehydrogenase YP_002346806.1 2056525 D 214092 CDS YP_002346807.1 218928932 1174647 2058739..2059800 1 NC_003143.1 sugar transport system permease 2059800 1174647 YPO1812 Yersinia pestis CO92 sugar transport system permease YP_002346807.1 2058739 D 214092 CDS YP_002346808.1 218928933 1174648 2059843..2060838 1 NC_003143.1 sugar-binding protein 2060838 1174648 YPO1813 Yersinia pestis CO92 sugar-binding protein YP_002346808.1 2059843 D 214092 CDS YP_002346809.1 218928934 1174649 2060904..2062481 1 NC_003143.1 sugar ABC transporter ATP-binding protein 2062481 1174649 YPO1814 Yersinia pestis CO92 sugar ABC transporter ATP-binding protein YP_002346809.1 2060904 D 214092 CDS YP_002346810.1 218928935 1174650 2062577..2063506 1 NC_003143.1 sugar ABC transporter permease 2063506 1174650 YPO1815 Yersinia pestis CO92 sugar ABC transporter permease YP_002346810.1 2062577 D 214092 CDS YP_002346811.1 218928936 1174651 2063555..2064514 1 NC_003143.1 sugar kinase 2064514 1174651 YPO1816 Yersinia pestis CO92 sugar kinase YP_002346811.1 2063555 D 214092 CDS YP_002346812.1 218928937 1174652 complement(2064772..2065191) 1 NC_003143.1 hypothetical protein 2065191 1174652 YPO1817 Yersinia pestis CO92 hypothetical protein YP_002346812.1 2064772 R 214092 CDS YP_002346813.2 537470171 1174653 complement(2065236..2065418) 1 NC_003143.1 hypothetical protein 2065418 1174653 YPO1818 Yersinia pestis CO92 hypothetical protein YP_002346813.2 2065236 R 214092 CDS YP_002346814.1 218928939 1174654 complement(2065625..2066407) 1 NC_003143.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 2066407 fliR 1174654 fliR Yersinia pestis CO92 flagellar biosynthesis protein FliR YP_002346814.1 2065625 R 214092 CDS YP_002346815.1 218928940 1174655 complement(2066410..2066679) 1 NC_003143.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 2066679 fliQ 1174655 fliQ Yersinia pestis CO92 flagellar biosynthesis protein FliQ YP_002346815.1 2066410 R 214092 CDS YP_002346816.1 218928941 1174656 complement(2066785..2067609) 1 NC_003143.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 2067609 fliP 1174656 fliP Yersinia pestis CO92 flagellar biosynthesis protein FliP YP_002346816.1 2066785 R 214092 CDS YP_002346817.2 537470172 1174657 complement(2067606..2068142) 1 NC_003143.1 flagellar protein FliO 2068142 fliO 1174657 fliO Yersinia pestis CO92 flagellar protein FliO YP_002346817.2 2067606 R 214092 CDS YP_002346818.1 218928943 1174658 complement(2068142..2068558) 1 NC_003143.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 2068558 fliN 1174658 fliN Yersinia pestis CO92 flagellar motor switch protein FliN YP_002346818.1 2068142 R 214092 CDS YP_002346819.1 218928944 1174659 complement(2068555..2069556) 1 NC_003143.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 2069556 fliM 1174659 fliM Yersinia pestis CO92 flagellar motor switch protein FliM YP_002346819.1 2068555 R 214092 CDS YP_002346820.1 218928945 1174660 complement(2069562..2070032) 1 NC_003143.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body protein FliL 2070032 fliL 1174660 fliL Yersinia pestis CO92 flagellar basal body protein FliL YP_002346820.1 2069562 R 214092 CDS YP_002346821.1 218928946 1174661 complement(2070299..2071651) 1 NC_003143.1 flagellar hook-length control protein FliK 2071651 fliK 1174661 fliK Yersinia pestis CO92 flagellar hook-length control protein FliK YP_002346821.1 2070299 R 214092 CDS YP_002346822.1 218928947 1174662 complement(2071648..2072094) 1 NC_003143.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 2072094 fliJ 1174662 fliJ Yersinia pestis CO92 flagellar biosynthesis chaperone YP_002346822.1 2071648 R 214092 CDS YP_002346823.1 218928948 1174663 complement(2072194..2073648) 1 NC_003143.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 2073648 fliI 1174663 fliI Yersinia pestis CO92 flagellum-specific ATP synthase YP_002346823.1 2072194 R 214092 CDS YP_002346824.1 218928949 1174664 complement(2073611..2074327) 1 NC_003143.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 2074327 fliH 1174664 fliH Yersinia pestis CO92 flagellar assembly protein H YP_002346824.1 2073611 R 214092 CDS YP_002346825.1 218928950 1174665 complement(2074320..2075312) 1 NC_003143.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 2075312 fliG 1174665 fliG Yersinia pestis CO92 flagellar motor switch protein G YP_002346825.1 2074320 R 214092 CDS YP_002346826.1 218928951 1174666 complement(2075309..2077021) 1 NC_003143.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 2077021 fliF 1174666 fliF Yersinia pestis CO92 flagellar MS-ring protein YP_002346826.1 2075309 R 214092 CDS YP_002346827.1 218928952 1174667 2077374..2077685 1 NC_003143.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 2077685 fliE 1174667 fliE Yersinia pestis CO92 flagellar hook-basal body protein FliE YP_002346827.1 2077374 D 214092 CDS YP_002346828.2 559797715 1174668 2078073..2078252 1 NC_003143.1 No significant database hits; hypothetical protein 2078252 1174668 YPO1832 Yersinia pestis CO92 hypothetical protein YP_002346828.2 2078073 D 214092 CDS YP_002346829.1 218928954 1174669 2078263..2078739 1 NC_003143.1 hypothetical protein 2078739 1174669 YPO1833 Yersinia pestis CO92 hypothetical protein YP_002346829.1 2078263 D 214092 CDS YP_002346830.1 218928955 1174670 complement(2078925..2079536) 1 NC_003143.1 glycosidase 2079536 1174670 YPO1834 Yersinia pestis CO92 glycosidase YP_002346830.1 2078925 R 214092 CDS YP_002346831.1 218928956 1174672 complement(2083006..2083881) 1 NC_003143.1 AraC family transcriptional regulator 2083881 1174672 YPO1837 Yersinia pestis CO92 AraC family transcriptional regulator YP_002346831.1 2083006 R 214092 CDS YP_002346833.1 218928958 1174674 complement(2084182..2084544) 1 NC_003143.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 2084544 fliT 1174674 fliT Yersinia pestis CO92 flagellar biosynthesis protein FliT YP_002346833.1 2084182 R 214092 CDS YP_002346834.1 218928959 1174675 complement(2084555..2084953) 1 NC_003143.1 flagellin specific chaperone; flagellar protein FliS 2084953 fliS 1174675 fliS Yersinia pestis CO92 flagellar protein FliS YP_002346834.1 2084555 R 214092 CDS YP_002346835.1 218928960 1174676 complement(2084964..2086364) 1 NC_003143.1 involved in flagellin assembly; flagellar capping protein 2086364 fliD 1174676 fliD Yersinia pestis CO92 flagellar capping protein YP_002346835.1 2084964 R 214092 CDS YP_002346836.1 218928961 1174677 2086661..2087770 1 NC_003143.1 structural flagella protein; flagellin 2087770 fliC 1174677 fliC Yersinia pestis CO92 flagellin YP_002346836.1 2086661 D 214092 CDS YP_002346837.1 218928962 1174678 2088117..2088839 1 NC_003143.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 2088839 fliA 1174678 fliA Yersinia pestis CO92 flagellar biosynthesis sigma factor YP_002346837.1 2088117 D 214092 CDS YP_002346838.1 218928963 1174679 2089061..2089570 1 NC_003143.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 2089570 fliZ 1174679 fliZ Yersinia pestis CO92 flagella biosynthesis protein FliZ YP_002346838.1 2089061 D 214092 CDS YP_002346839.1 218928964 1174680 2089859..2090851 1 NC_003143.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 2090851 yedO 1174680 yedO Yersinia pestis CO92 D-cysteine desulfhydrase YP_002346839.1 2089859 D 214092 CDS YP_002346840.1 218928965 1174681 2090975..2091775 1 NC_003143.1 cystine transporter subunit 2091775 fliY 1174681 fliY Yersinia pestis CO92 cystine transporter subunit YP_002346840.1 2090975 D 214092 CDS YP_002346841.1 218928966 1174682 2091775..2092437 1 NC_003143.1 amino-acid ABC transporter permease 2092437 yecS 1174682 yecS Yersinia pestis CO92 amino-acid ABC transporter permease YP_002346841.1 2091775 D 214092 CDS YP_002346842.1 218928967 1174683 2092440..2093201 1 NC_003143.1 amino-acid ABC transporter ATP-binding protein YecC 2093201 yecC 1174683 yecC Yersinia pestis CO92 amino-acid ABC transporter ATP-binding protein YecC YP_002346842.1 2092440 D 214092 CDS YP_002346843.1 218928968 1174684 complement(2093493..2093831) 1 NC_003143.1 hypothetical protein 2093831 1174684 YPO1849 Yersinia pestis CO92 hypothetical protein YP_002346843.1 2093493 R 214092 CDS YP_002346844.1 218928969 1174685 complement(2093865..2094200) 1 NC_003143.1 No significant database hits; hypothetical protein 2094200 1174685 YPO1850 Yersinia pestis CO92 hypothetical protein YP_002346844.1 2093865 R 214092 CDS YP_002346845.1 218928970 1174686 complement(2094664..2098635) 1 NC_003143.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 2098635 putA 1174686 putA Yersinia pestis CO92 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_002346845.1 2094664 R 214092 CDS YP_002346847.1 218928972 1174688 2099207..2100691 1 NC_003143.1 proline permease 2100691 putP 1174688 putP Yersinia pestis CO92 proline permease YP_002346847.1 2099207 D 214092 CDS YP_002346848.1 218928973 1174689 2101024..2101872 1 NC_003143.1 hypothetical protein 2101872 1174689 YPO1854 Yersinia pestis CO92 hypothetical protein YP_002346848.1 2101024 D 214092 CDS YP_002346849.1 218928974 1174690 2101902..2103032 1 NC_003143.1 hypothetical protein 2103032 1174690 YPO1855 Yersinia pestis CO92 hypothetical protein YP_002346849.1 2101902 D 214092 CDS YP_002346850.1 218928975 1174691 2103043..2104347 1 NC_003143.1 hypothetical protein 2104347 1174691 YPO1856 Yersinia pestis CO92 hypothetical protein YP_002346850.1 2103043 D 214092 CDS YP_002346851.1 218928976 1174692 complement(2104433..2105032) 1 NC_003143.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 2105032 wrbA 1174692 wrbA Yersinia pestis CO92 TrpR binding protein WrbA YP_002346851.1 2104433 R 214092 CDS YP_002346852.1 218928977 1174693 2105426..2106604 1 NC_003143.1 N-acetylneuraminic acid mutarotase 2106604 1174693 YPO1858 Yersinia pestis CO92 N-acetylneuraminic acid mutarotase YP_002346852.1 2105426 D 214092 CDS YP_002346853.1 218928978 1174694 complement(2106730..2108154) 1 NC_003143.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 2108154 cycA 1174694 cycA Yersinia pestis CO92 D-alanine/D-serine/glycine permease YP_002346853.1 2106730 R 214092 CDS YP_002346854.1 218928979 1174696 2109269..2109820 1 NC_003143.1 attachment invasion locus protein 2109820 ail 1174696 ail Yersinia pestis CO92 attachment invasion locus protein YP_002346854.1 2109269 D 214092 CDS YP_002346856.1 218928981 1174698 2110160..2110414 1 NC_003143.1 hypothetical protein 2110414 1174698 YPO1862 Yersinia pestis CO92 hypothetical protein YP_002346856.1 2110160 D 214092 CDS YP_002346857.1 218928982 1174699 complement(2110442..2110783) 1 NC_003143.1 hypothetical protein 2110783 glpM 1174699 glpM Yersinia pestis CO92 hypothetical protein YP_002346857.1 2110442 R 214092 CDS YP_002346858.1 218928983 1174700 complement(2110911..2111135) 1 NC_003143.1 hypothetical protein 2111135 1174700 YPO1864 Yersinia pestis CO92 hypothetical protein YP_002346858.1 2110911 R 214092 CDS YP_002346859.1 218928984 1174701 2111798..2112454 1 NC_003143.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 2112454 uvrY 1174701 uvrY Yersinia pestis CO92 response regulator YP_002346859.1 2111798 D 214092 CDS YP_002346860.1 218928985 1174702 2112426..2114279 1 NC_003143.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 2114279 uvrC 1174702 uvrC Yersinia pestis CO92 excinuclease ABC subunit C YP_002346860.1 2112426 D 214092 CDS YP_002346861.1 218928986 1174703 2114338..2114886 1 NC_003143.1 phosphatidylglycerophosphate synthetase 2114886 pgsA 1174703 pgsA Yersinia pestis CO92 phosphatidylglycerophosphate synthetase YP_002346861.1 2114338 D 214092 CDS YP_002346862.1 218928987 1174707 complement(2115626..2116141) 1 NC_003143.1 hypothetical protein 2116141 1174707 YPO1868 Yersinia pestis CO92 hypothetical protein YP_002346862.1 2115626 R 214092 CDS YP_002346864.1 218928989 1174709 2116848..2116994 1 NC_003143.1 No significant database hits; hypothetical protein 2116994 1174709 YPO1870 Yersinia pestis CO92 hypothetical protein YP_002346864.1 2116848 D 214092 CDS YP_008479710.1 537470173 16744761 2117239..2117412 1 NC_003143.1 hypothetical protein 2117412 16744761 YPO1870a Yersinia pestis CO92 hypothetical protein YP_008479710.1 2117239 D 214092 CDS YP_002346867.1 218928992 1174712 complement(2118567..2119526) 1 NC_003143.1 transposase 2119526 tnpA 1174712 tnpA Yersinia pestis CO92 transposase YP_002346867.1 2118567 R 214092 CDS YP_002346868.1 218928993 1174713 complement(2119598..2120044) 1 NC_003143.1 hypothetical protein 2120044 1174713 YPO1874 Yersinia pestis CO92 hypothetical protein YP_002346868.1 2119598 R 214092 CDS YP_002346870.1 218928995 1174715 complement(2120433..2120687) 1 NC_003143.1 hypothetical protein 2120687 1174715 YPO1876 Yersinia pestis CO92 hypothetical protein YP_002346870.1 2120433 R 214092 CDS YP_002346873.1 218928998 1174718 complement(2121644..2121931) 1 NC_003143.1 hypothetical protein 2121931 1174718 YPO1879 Yersinia pestis CO92 hypothetical protein YP_002346873.1 2121644 R 214092 CDS YP_002346874.1 218928999 1174719 complement(2121948..2122247) 1 NC_003143.1 hypothetical protein 2122247 1174719 YPO1880 Yersinia pestis CO92 hypothetical protein YP_002346874.1 2121948 R 214092 CDS YP_002346875.1 218929000 1174720 complement(2122244..2122603) 1 NC_003143.1 hypothetical protein 2122603 1174720 YPO1881 Yersinia pestis CO92 hypothetical protein YP_002346875.1 2122244 R 214092 CDS YP_002346876.1 218929001 1174721 2122887..2123177 1 NC_003143.1 hypothetical protein 2123177 1174721 YPO1882 Yersinia pestis CO92 hypothetical protein YP_002346876.1 2122887 D 214092 CDS YP_008479711.1 537470174 1174722 2123243..2124319 1 NC_003143.1 hypothetical protein 2124319 1174722 YPO1883 Yersinia pestis CO92 hypothetical protein YP_008479711.1 2123243 D 214092 CDS YP_002346877.1 218929002 1174724 complement(2125983..2126552) 1 NC_003143.1 hypothetical protein 2126552 1174724 YPO1886 Yersinia pestis CO92 hypothetical protein YP_002346877.1 2125983 R 214092 CDS YP_002346878.1 218929003 1174725 complement(2126564..2126998) 1 NC_003143.1 hypothetical protein 2126998 1174725 YPO1887 Yersinia pestis CO92 hypothetical protein YP_002346878.1 2126564 R 214092 CDS YP_002346880.1 218929005 1174728 2127967..2128764 1 NC_003143.1 GntR family transcriptional regulator 2128764 1174728 YPO1890 Yersinia pestis CO92 GntR family transcriptional regulator YP_002346880.1 2127967 D 214092 CDS YP_002346882.1 218929007 1174730 2129432..2130445 1 NC_003143.1 oxidoreductase 2130445 1174730 YPO1892 Yersinia pestis CO92 oxidoreductase YP_002346882.1 2129432 D 214092 CDS YP_002346883.1 218929008 1174731 2130475..2131743 1 NC_003143.1 exported solute-binding protein 2131743 1174731 YPO1893 Yersinia pestis CO92 exported solute-binding protein YP_002346883.1 2130475 D 214092 CDS YP_002346884.1 218929009 1174732 2131810..2132670 1 NC_003143.1 binding-protein-dependent transporter inner membrane component 2132670 1174732 YPO1894 Yersinia pestis CO92 binding-protein-dependent transporter inner membrane component YP_002346884.1 2131810 D 214092 CDS YP_002346885.1 218929010 1174733 2132663..2133490 1 NC_003143.1 binding-protein-dependent transporter inner membrane component 2133490 1174733 YPO1895 Yersinia pestis CO92 binding-protein-dependent transporter inner membrane component YP_002346885.1 2132663 D 214092 CDS YP_002346888.1 218929013 1174736 complement(2134882..2135067) 1 NC_003143.1 hypothetical protein 2135067 1174736 YPO1898 Yersinia pestis CO92 hypothetical protein YP_002346888.1 2134882 R 214092 CDS YP_002346890.1 218929015 1174738 2135545..2136567 1 NC_003143.1 transposase for insertion sequence IS100 2136567 y1093 1174738 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346890.1 2135545 D 214092 CDS YP_002346891.1 218929016 1174739 2136564..2137346 1 NC_003143.1 transposase/IS protein 2137346 1174739 YPO1901 Yersinia pestis CO92 transposase/IS protein YP_002346891.1 2136564 D 214092 CDS YP_002346892.1 218929017 1174740 complement(2137945..2138526) 1 NC_003143.1 hypothetical protein 2138526 1174740 YPO1902 Yersinia pestis CO92 hypothetical protein YP_002346892.1 2137945 R 214092 CDS YP_002346893.1 218929018 1174741 complement(2138532..2138696) 1 NC_003143.1 hypothetical protein 2138696 1174741 YPO1903 Yersinia pestis CO92 hypothetical protein YP_002346893.1 2138532 R 214092 CDS YP_002346894.2 559797716 1174742 complement(2138715..2138900) 1 NC_003143.1 transcriptional regulator 2138900 1174742 YPO1904 Yersinia pestis CO92 transcriptional regulator YP_002346894.2 2138715 R 214092 CDS YP_002346897.1 218929022 1174745 complement(2140840..2142861) 1 NC_003143.1 pesticin/yersiniabactin receptor protein 2142861 fyuA 1174745 fyuA Yersinia pestis CO92 pesticin/yersiniabactin receptor protein YP_002346897.1 2140840 R 214092 CDS YP_002346898.1 218929023 1174746 complement(2142992..2144569) 1 NC_003143.1 yersiniabactin siderophore biosynthetic protein 2144569 irp5 1174746 irp5 Yersinia pestis CO92 yersiniabactin siderophore biosynthetic protein YP_002346898.1 2142992 R 214092 CDS YP_002346899.1 218929024 1174747 complement(2144573..2145376) 1 NC_003143.1 yersiniabactin biosynthetic protein YbtT 2145376 irp4 1174747 irp4 Yersinia pestis CO92 yersiniabactin biosynthetic protein YbtT YP_002346899.1 2144573 R 214092 CDS YP_002346900.1 218929025 1174748 complement(2145373..2146473) 1 NC_003143.1 yersiniabactin biosynthetic protein YbtU 2146473 irp3 1174748 irp3 Yersinia pestis CO92 yersiniabactin biosynthetic protein YbtU YP_002346900.1 2145373 R 214092 CDS YP_002346901.1 218929026 1174749 complement(2146470..2155961) 1 NC_003143.1 yersiniabactin biosynthetic protein 2155961 irp1 1174749 irp1 Yersinia pestis CO92 yersiniabactin biosynthetic protein YP_002346901.1 2146470 R 214092 CDS YP_002346902.1 218929027 1174750 complement(2156049..2162156) 1 NC_003143.1 yersiniabactin biosynthetic protein 2162156 irp2 1174750 irp2 Yersinia pestis CO92 yersiniabactin biosynthetic protein YP_002346902.1 2156049 R 214092 CDS YP_002346903.1 218929028 1174751 complement(2162347..2163306) 1 NC_003143.1 transcriptional regulator YbtA 2163306 ybtA 1174751 ybtA Yersinia pestis CO92 transcriptional regulator YbtA YP_002346903.1 2162347 R 214092 CDS YP_002346904.1 218929029 1174752 2163473..2165275 1 NC_003143.1 lipoprotein inner membrane ABC transporter 2165275 irp6 1174752 irp6 Yersinia pestis CO92 lipoprotein inner membrane ABC transporter YP_002346904.1 2163473 D 214092 CDS YP_002346905.1 218929030 1174753 2165262..2167064 1 NC_003143.1 ABC transporter permease 2167064 irp7 1174753 irp7 Yersinia pestis CO92 ABC transporter permease YP_002346905.1 2165262 D 214092 CDS YP_002346906.1 218929031 1174754 2167057..2168337 1 NC_003143.1 signal transducer 2168337 irp8 1174754 irp8 Yersinia pestis CO92 signal transducer YP_002346906.1 2167057 D 214092 CDS YP_002346907.1 218929032 1174755 2168365..2169669 1 NC_003143.1 catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin; salicylate synthase Irp9 2169669 ybtS 1174755 ybtS Yersinia pestis CO92 salicylate synthase Irp9 YP_002346907.1 2168365 D 214092 CDS YP_002346908.1 218929033 1174756 complement(2169863..2171125) 1 NC_003143.1 integrase 2171125 int 1174756 int Yersinia pestis CO92 integrase YP_002346908.1 2169863 R 214092 CDS YP_002346909.1 218929034 1174758 complement(2171665..2172405) 1 NC_003143.1 pili assembly chaperone 2172405 1174758 YPO1918 Yersinia pestis CO92 pili assembly chaperone YP_002346909.1 2171665 R 214092 CDS YP_002346910.1 218929035 1174759 complement(2172402..2173751) 1 NC_003143.1 hypothetical protein 2173751 1174759 YPO1919 Yersinia pestis CO92 hypothetical protein YP_002346910.1 2172402 R 214092 CDS YP_002346911.1 218929036 1174760 complement(2173767..2176358) 1 NC_003143.1 fimbrial usher protein 2176358 1174760 YPO1920 Yersinia pestis CO92 fimbrial usher protein YP_002346911.1 2173767 R 214092 CDS YP_002346912.1 218929037 1174761 complement(2176407..2177051) 1 NC_003143.1 pili assembly chaperone 2177051 1174761 YPO1921 Yersinia pestis CO92 pili assembly chaperone YP_002346912.1 2176407 R 214092 CDS YP_002346913.1 218929038 1174762 complement(2177144..2177674) 1 NC_003143.1 fimbrial protein 2177674 1174762 YPO1922 Yersinia pestis CO92 fimbrial protein YP_002346913.1 2177144 R 214092 CDS YP_002346914.1 218929039 1174764 complement(2182012..2182644) 1 NC_003143.1 two-component response regulator 2182644 1174764 YPO1925 Yersinia pestis CO92 two-component response regulator YP_002346914.1 2182012 R 214092 CDS YP_002346915.1 218929040 1174765 complement(2183470..2184792) 1 NC_003143.1 4-hydroxybutyrate CoA-transferase 2184792 1174765 YPO1926 Yersinia pestis CO92 4-hydroxybutyrate CoA-transferase YP_002346915.1 2183470 R 214092 CDS YP_002346916.1 218929041 1174766 complement(2184815..2185357) 1 NC_003143.1 transcription regulatory protein 2185357 1174766 YPO1927 Yersinia pestis CO92 transcription regulatory protein YP_002346916.1 2184815 R 214092 CDS YP_002346917.1 218929042 1174767 complement(2185407..2186249) 1 NC_003143.1 citrate lyase subunit beta 2186249 1174767 YPO1928 Yersinia pestis CO92 citrate lyase subunit beta YP_002346917.1 2185407 R 214092 CDS YP_002346918.1 218929043 1174768 2186344..2187222 1 NC_003143.1 LysR family transcriptional regulator 2187222 1174768 YPO1929 Yersinia pestis CO92 LysR family transcriptional regulator YP_002346918.1 2186344 D 214092 CDS YP_002346919.1 218929044 1174769 complement(2187297..2187770) 1 NC_003143.1 lipoprotein 2187770 1174769 YPO1930 Yersinia pestis CO92 lipoprotein YP_002346919.1 2187297 R 214092 CDS YP_002346920.1 218929045 1174770 complement(2187795..2188355) 1 NC_003143.1 hypothetical protein 2188355 1174770 YPO1931 Yersinia pestis CO92 hypothetical protein YP_002346920.1 2187795 R 214092 CDS YP_002346921.1 218929046 1174771 complement(2188575..2189804) 1 NC_003143.1 sugar transporter 2189804 1174771 YPO1932 Yersinia pestis CO92 sugar transporter YP_002346921.1 2188575 R 214092 CDS YP_002346922.1 218929047 1174772 complement(2189870..2190739) 1 NC_003143.1 dicarboxylic acid hydrolase 2190739 1174772 YPO1933 Yersinia pestis CO92 dicarboxylic acid hydrolase YP_002346922.1 2189870 R 214092 CDS YP_002346923.1 218929048 1174773 2190851..2191813 1 NC_003143.1 LysR family transcriptional regulator 2191813 1174773 YPO1934 Yersinia pestis CO92 LysR family transcriptional regulator YP_002346923.1 2190851 D 214092 CDS YP_002346924.1 218929049 1174774 complement(2192118..2192717) 1 NC_003143.1 Part of the NQR complex which has six subunits NqrA, NqrB, NqrC, NqrD, NqrE and NqrF. NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Na(+)-translocating NADH-quinone reductase subunit E 2192717 1174774 YPO1935 Yersinia pestis CO92 Na(+)-translocating NADH-quinone reductase subunit E YP_002346924.1 2192118 R 214092 CDS YP_002346925.1 218929050 1174775 2193069..2194229 1 NC_003143.1 aminotransferase 2194229 1174775 YPO1936 Yersinia pestis CO92 aminotransferase YP_002346925.1 2193069 D 214092 CDS YP_002346926.1 218929051 1174776 complement(2194425..2195951) 1 NC_003143.1 L-asparagine permease 2195951 ansP 1174776 ansP Yersinia pestis CO92 L-asparagine permease YP_002346926.1 2194425 R 214092 CDS YP_002346927.1 218929052 1174777 complement(2196676..2197446) 1 NC_003143.1 deoR family transcriptional regulator 2197446 1174777 YPO1938 Yersinia pestis CO92 deoR family transcriptional regulator YP_002346927.1 2196676 R 214092 CDS YP_002346928.1 218929053 1174778 2198642..2199664 1 NC_003143.1 catalyzes the formation of glutamate from glutamine; glutaminase 2199664 1174778 YPO1939 Yersinia pestis CO92 glutaminase YP_002346928.1 2198642 D 214092 CDS YP_002346929.1 218929054 1174779 2199775..2201415 1 NC_003143.1 hypothetical protein 2201415 1174779 YPO1940 Yersinia pestis CO92 hypothetical protein YP_002346929.1 2199775 D 214092 CDS YP_002346930.1 218929055 1174780 2201996..2203915 1 NC_003143.1 hypothetical protein 2203915 1174780 YPO1941 Yersinia pestis CO92 hypothetical protein YP_002346930.1 2201996 D 214092 CDS YP_002346931.1 218929056 1174781 2204119..2204646 1 NC_003143.1 hypothetical protein 2204646 1174781 YPO1942 Yersinia pestis CO92 hypothetical protein YP_002346931.1 2204119 D 214092 CDS YP_002346932.1 218929057 1174782 2204947..2206356 1 NC_003143.1 hypothetical protein 2206356 1174782 YPO1943 Yersinia pestis CO92 hypothetical protein YP_002346932.1 2204947 D 214092 CDS YP_002346933.1 218929058 1174783 2206359..2207651 1 NC_003143.1 hypothetical protein 2207651 1174783 YPO1944 Yersinia pestis CO92 hypothetical protein YP_002346933.1 2206359 D 214092 CDS YP_002346934.1 218929059 1174784 2207641..2208804 1 NC_003143.1 hypothetical protein 2208804 1174784 YPO1945 Yersinia pestis CO92 hypothetical protein YP_002346934.1 2207641 D 214092 CDS YP_002346935.1 218929060 1174785 2208808..2209521 1 NC_003143.1 ABC transporter ATP-binding protein 2209521 1174785 YPO1946 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002346935.1 2208808 D 214092 CDS YP_002346936.1 218929061 1174786 2209511..2210008 1 NC_003143.1 thioredoxin 2210008 1174786 YPO1947 Yersinia pestis CO92 thioredoxin YP_002346936.1 2209511 D 214092 CDS YP_002346937.1 218929062 1174787 2210008..2210319 1 NC_003143.1 cytochrome 2210319 1174787 YPO1948 Yersinia pestis CO92 cytochrome YP_002346937.1 2210008 D 214092 CDS YP_002346938.1 218929063 1174788 2210492..2211379 1 NC_003143.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 2211379 tehB 1174788 tehB Yersinia pestis CO92 tellurite resistance protein TehB YP_002346938.1 2210492 D 214092 CDS YP_002346939.1 218929064 1174789 2211520..2212737 1 NC_003143.1 endopeptidase 2212737 1174789 YPO1950 Yersinia pestis CO92 endopeptidase YP_002346939.1 2211520 D 214092 CDS YP_002346940.1 218929065 1174790 2213406..2215874 1 NC_003143.1 in Yersinia this protein is important for biofilm formation and hemin adsorption; hypothetical protein 2215874 hmsH 1174790 hmsH Yersinia pestis CO92 hypothetical protein YP_002346940.1 2213406 D 214092 CDS YP_002346941.1 218929066 1174791 2215887..2217908 1 NC_003143.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 2217908 hmsF 1174791 hmsF Yersinia pestis CO92 outer membrane N-deacetylase YP_002346941.1 2215887 D 214092 CDS YP_002346942.1 218929067 1174792 2217898..2219232 1 NC_003143.1 predicted polysaccharide polymerase involved in biofilm formation; in Escherichia coli the related protein PgaC is required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 2219232 hmsR 1174792 hmsR Yersinia pestis CO92 N-glycosyltransferase YP_002346942.1 2217898 D 214092 CDS YP_002346943.1 218929068 1174793 2219229..2219696 1 NC_003143.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; hemin storage system protein 2219696 hmsS 1174793 hmsS Yersinia pestis CO92 hemin storage system protein YP_002346943.1 2219229 D 214092 CDS YP_002346944.1 218929069 1174794 2220029..2220928 1 NC_003143.1 acetyltransferase 2220928 1174794 YPO1955 Yersinia pestis CO92 acetyltransferase YP_002346944.1 2220029 D 214092 CDS YP_002346945.1 218929070 1174795 2221367..2221645 1 NC_003143.1 hypothetical protein 2221645 1174795 YPO1956 Yersinia pestis CO92 hypothetical protein YP_002346945.1 2221367 D 214092 CDS YP_002346946.1 218929071 1174796 2221705..2222493 1 NC_003143.1 hypothetical protein 2222493 phoH 1174796 phoH Yersinia pestis CO92 hypothetical protein YP_002346946.1 2221705 D 214092 CDS YP_002346947.1 218929072 1174797 complement(2222596..2223696) 1 NC_003143.1 calcium/sodium:proton antiporter 2223696 chaA 1174797 chaA Yersinia pestis CO92 calcium/sodium:proton antiporter YP_002346947.1 2222596 R 214092 CDS YP_002346948.1 218929073 1174798 complement(2224245..2226026) 1 NC_003143.1 nitrate/nitrite sensor protein NarX 2226026 narX 1174798 narX Yersinia pestis CO92 nitrate/nitrite sensor protein NarX YP_002346948.1 2224245 R 214092 CDS YP_002346949.1 218929074 1174799 2226336..2227757 1 NC_003143.1 GntR family transcriptional regulator 2227757 1174799 YPO1960 Yersinia pestis CO92 GntR family transcriptional regulator YP_002346949.1 2226336 D 214092 CDS YP_002346951.1 218929076 1174801 2228394..2229638 1 NC_003143.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 2229638 argD 1174801 argD Yersinia pestis CO92 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_002346951.1 2228394 D 214092 CDS YP_002346952.1 218929077 1174802 2229668..2230720 1 NC_003143.1 arginine succinyltransferase 2230720 astA 1174802 astA Yersinia pestis CO92 arginine succinyltransferase YP_002346952.1 2229668 D 214092 CDS YP_002346953.1 218929078 1174803 2230717..2232234 1 NC_003143.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 2232234 astD 1174803 astD Yersinia pestis CO92 succinylglutamic semialdehyde dehydrogenase YP_002346953.1 2230717 D 214092 CDS YP_002346954.1 218929079 1174804 2232258..2233601 1 NC_003143.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 2233601 astB 1174804 astB Yersinia pestis CO92 succinylarginine dihydrolase YP_002346954.1 2232258 D 214092 CDS YP_002346955.1 218929080 1174805 2233662..2234654 1 NC_003143.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 2234654 astE 1174805 astE Yersinia pestis CO92 succinylglutamate desuccinylase YP_002346955.1 2233662 D 214092 CDS YP_002346956.1 218929081 1174807 2236351..2237397 1 NC_003143.1 transposase for insertion sequence IS100 2237397 y1093 1174807 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002346956.1 2236351 D 214092 CDS YP_002346957.1 218929082 1174808 2237397..2238149 1 NC_003143.1 transposase/IS protein 2238149 1174808 YPO1969 Yersinia pestis CO92 transposase/IS protein YP_002346957.1 2237397 D 214092 CDS YP_002346958.1 218929083 1174809 complement(2238726..2239532) 1 NC_003143.1 N-formylglutamate amidohydrolase 2239532 hutG 1174809 hutG Yersinia pestis CO92 N-formylglutamate amidohydrolase YP_002346958.1 2238726 R 214092 CDS YP_002346959.1 218929084 1174810 complement(2239529..2240749) 1 NC_003143.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 2240749 hutI 1174810 hutI Yersinia pestis CO92 imidazolonepropionase YP_002346959.1 2239529 R 214092 CDS YP_002346960.1 218929085 1174811 complement(2240953..2241720) 1 NC_003143.1 GntR family transcriptional regulator 2241720 hutC 1174811 hutC Yersinia pestis CO92 GntR family transcriptional regulator YP_002346960.1 2240953 R 214092 CDS YP_002346961.1 218929086 1174812 2241868..2243238 1 NC_003143.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate; N-formimino-L-glutamate deiminase 2243238 1174812 YPO1974 Yersinia pestis CO92 N-formimino-L-glutamate deiminase YP_002346961.1 2241868 D 214092 CDS YP_002346962.1 218929087 1174813 2243238..2243810 1 NC_003143.1 hypothetical protein 2243810 1174813 YPO1975 Yersinia pestis CO92 hypothetical protein YP_002346962.1 2243238 D 214092 CDS YP_002346963.1 218929088 1174814 complement(2243988..2245964) 1 NC_003143.1 hypothetical protein 2245964 1174814 YPO1976 Yersinia pestis CO92 hypothetical protein YP_002346963.1 2243988 R 214092 CDS YP_002346964.1 218929089 1174816 2247623..2248639 1 NC_003143.1 dehydrogenase 2248639 1174816 YPO1979 Yersinia pestis CO92 dehydrogenase YP_002346964.1 2247623 D 214092 CDS YP_002346965.1 218929090 1174817 2248632..2249438 1 NC_003143.1 hypothetical protein 2249438 1174817 YPO1980 Yersinia pestis CO92 hypothetical protein YP_002346965.1 2248632 D 214092 CDS YP_002346966.1 218929091 1174818 2249435..2250721 1 NC_003143.1 coenzyme synthetase 2250721 1174818 YPO1981 Yersinia pestis CO92 coenzyme synthetase YP_002346966.1 2249435 D 214092 CDS YP_002346967.1 218929092 1174819 2250855..2251817 1 NC_003143.1 dehydrogenase 2251817 1174819 YPO1982 Yersinia pestis CO92 dehydrogenase YP_002346967.1 2250855 D 214092 CDS YP_002346968.1 218929093 1174820 2251817..2252971 1 NC_003143.1 glycosyl transferase 2252971 1174820 YPO1983 Yersinia pestis CO92 glycosyl transferase YP_002346968.1 2251817 D 214092 CDS YP_002346969.1 218929094 1174821 2252968..2253552 1 NC_003143.1 Doubtful CDS. No significant database hits; hypothetical protein 2253552 1174821 YPO1984 Yersinia pestis CO92 hypothetical protein YP_002346969.1 2252968 D 214092 CDS YP_002346970.1 218929095 1174822 2253549..2254736 1 NC_003143.1 glycosyl transferase 2254736 1174822 YPO1985 Yersinia pestis CO92 glycosyl transferase YP_002346970.1 2253549 D 214092 CDS YP_002346971.1 218929096 1174823 complement(2254897..2255361) 1 NC_003143.1 hypothetical protein 2255361 1174823 YPO1986 Yersinia pestis CO92 hypothetical protein YP_002346971.1 2254897 R 214092 CDS YP_002346972.1 218929097 1174824 complement(2255531..2257189) 1 NC_003143.1 No significant database hits; hypothetical protein 2257189 1174824 YPO1987 Yersinia pestis CO92 hypothetical protein YP_002346972.1 2255531 R 214092 CDS YP_002346973.1 218929098 1174825 2257308..2258516 1 NC_003143.1 transposase for the IS285 insertion element 2258516 y1062 1174825 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002346973.1 2257308 D 214092 CDS YP_002346974.1 218929099 1174826 complement(2258636..2260798) 1 NC_003143.1 hypothetical protein 2260798 1174826 YPO1989 Yersinia pestis CO92 hypothetical protein YP_002346974.1 2258636 R 214092 CDS YP_002346975.1 218929100 1174827 2261376..2263487 1 NC_003143.1 hypothetical protein 2263487 1174827 YPO1990 Yersinia pestis CO92 hypothetical protein YP_002346975.1 2261376 D 214092 CDS YP_002346976.1 218929101 1174828 2263734..2264372 1 NC_003143.1 hypothetical protein 2264372 1174828 YPO1991 Yersinia pestis CO92 hypothetical protein YP_002346976.1 2263734 D 214092 CDS YP_002346977.1 218929102 1174829 complement(2264507..2265166) 1 NC_003143.1 hypothetical protein 2265166 1174829 YPO1992 Yersinia pestis CO92 hypothetical protein YP_002346977.1 2264507 R 214092 CDS YP_002346978.1 218929103 1174830 complement(2265271..2265951) 1 NC_003143.1 dehydrogenase 2265951 1174830 YPO1993 Yersinia pestis CO92 dehydrogenase YP_002346978.1 2265271 R 214092 CDS YP_002346979.1 218929104 1174831 complement(2266292..2267242) 1 NC_003143.1 hypothetical protein 2267242 1174831 YPO1994 Yersinia pestis CO92 hypothetical protein YP_002346979.1 2266292 R 214092 CDS YP_002346980.1 218929105 1174832 complement(2267229..2268161) 1 NC_003143.1 hypothetical protein 2268161 1174832 YPO1995 Yersinia pestis CO92 hypothetical protein YP_002346980.1 2267229 R 214092 CDS YP_002346981.1 218929106 1174833 complement(2268167..2269072) 1 NC_003143.1 No significant database hits; hypothetical protein 2269072 1174833 YPO1996 Yersinia pestis CO92 hypothetical protein YP_002346981.1 2268167 R 214092 CDS YP_002346982.1 218929107 1174834 complement(2269863..2270936) 1 NC_003143.1 hypothetical protein 2270936 1174834 YPO1997 Yersinia pestis CO92 hypothetical protein YP_002346982.1 2269863 R 214092 CDS YP_002346983.1 218929108 1174835 complement(2271149..2271619) 1 NC_003143.1 hypothetical protein 2271619 1174835 YPO1998 Yersinia pestis CO92 hypothetical protein YP_002346983.1 2271149 R 214092 CDS YP_002346984.1 218929109 1174836 complement(2271674..2272096) 1 NC_003143.1 decarboxylase 2272096 1174836 YPO1999 Yersinia pestis CO92 decarboxylase YP_002346984.1 2271674 R 214092 CDS YP_002346985.1 218929110 1174837 complement(2272373..2273764) 1 NC_003143.1 two-component system sensor protein 2273764 1174837 YPO2000 Yersinia pestis CO92 two-component system sensor protein YP_002346985.1 2272373 R 214092 CDS YP_002346986.1 218929111 1174838 complement(2273770..2274462) 1 NC_003143.1 transcriptional activator 2274462 copR 1174838 copR Yersinia pestis CO92 transcriptional activator YP_002346986.1 2273770 R 214092 CDS YP_002346987.1 218929112 1174839 2274727..2275818 1 NC_003143.1 hypothetical protein 2275818 1174839 YPO2002 Yersinia pestis CO92 hypothetical protein YP_002346987.1 2274727 D 214092 CDS YP_002346988.1 218929113 1174840 2275967..2276674 1 NC_003143.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 2276674 1174840 YPO2003 Yersinia pestis CO92 flavodoxin YP_002346988.1 2275967 D 214092 CDS YP_002346989.1 218929114 1174841 2276689..2277384 1 NC_003143.1 hypothetical protein 2277384 1174841 YPO2004 Yersinia pestis CO92 hypothetical protein YP_002346989.1 2276689 D 214092 CDS YP_002346990.1 218929115 1174842 complement(2277593..2278435) 1 NC_003143.1 hypothetical protein 2278435 1174842 YPO2005 Yersinia pestis CO92 hypothetical protein YP_002346990.1 2277593 R 214092 CDS YP_002346991.1 218929116 1174843 2279186..2279722 1 NC_003143.1 No significant database hits; hypothetical protein 2279722 1174843 YPO2006 Yersinia pestis CO92 hypothetical protein YP_002346991.1 2279186 D 214092 CDS YP_002346992.1 218929117 1174844 2279719..2280549 1 NC_003143.1 esterase 2280549 1174844 YPO2007 Yersinia pestis CO92 esterase YP_002346992.1 2279719 D 214092 CDS YP_002346993.1 218929118 1174845 2280557..2280955 1 NC_003143.1 rhodanese-like protein 2280955 1174845 YPO2008 Yersinia pestis CO92 rhodanese-like protein YP_002346993.1 2280557 D 214092 CDS YP_002346994.1 218929119 1174846 complement(2281003..2281512) 1 NC_003143.1 integrase core domain-containing protein 2281512 1174846 YPO2009 Yersinia pestis CO92 integrase core domain-containing protein YP_002346994.1 2281003 R 214092 CDS YP_002346996.1 218929121 1174848 complement(2282141..2283232) 1 NC_003143.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 2283232 ychF 1174848 ychF Yersinia pestis CO92 GTP-dependent nucleic acid-binding protein EngD YP_002346996.1 2282141 R 214092 CDS YP_002346997.1 218929122 1174849 complement(2283396..2283986) 1 NC_003143.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 2283986 pth 1174849 pth Yersinia pestis CO92 peptidyl-tRNA hydrolase YP_002346997.1 2283396 R 214092 CDS YP_002346998.1 218929123 1174850 2284348..2284620 1 NC_003143.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 2284620 1174850 YPO2012 Yersinia pestis CO92 hypothetical protein YP_002346998.1 2284348 D 214092 CDS YP_002346999.1 218929124 1174851 complement(2284822..2285769) 1 NC_003143.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 2285769 prsA 1174851 prsA Yersinia pestis CO92 ribose-phosphate pyrophosphokinase YP_002346999.1 2284822 R 214092 CDS YP_002347000.1 218929125 1174852 complement(2286110..2287009) 1 NC_003143.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 2287009 ipk 1174852 ipk Yersinia pestis CO92 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002347000.1 2286110 R 214092 CDS YP_002347001.1 218929126 1174853 complement(2287011..2287634) 1 NC_003143.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; molecular chaperone LolB 2287634 lolB 1174853 lolB Yersinia pestis CO92 molecular chaperone LolB YP_002347001.1 2287011 R 214092 CDS YP_002347002.1 218929127 1174854 2287940..2289202 1 NC_003143.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 2289202 hemA 1174854 hemA Yersinia pestis CO92 glutamyl-tRNA reductase YP_002347002.1 2287940 D 214092 CDS YP_002347003.1 218929128 1174855 2289235..2290317 1 NC_003143.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 2290317 prfA 1174855 prfA Yersinia pestis CO92 peptide chain release factor 1 YP_002347003.1 2289235 D 214092 CDS YP_002347004.1 218929129 1174856 2290317..2291147 1 NC_003143.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 2291147 1174856 YPO2018 Yersinia pestis CO92 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002347004.1 2290317 D 214092 CDS YP_002347005.1 218929130 1174857 2291211..2291612 1 NC_003143.1 hypothetical protein 2291612 1174857 YPO2019 Yersinia pestis CO92 hypothetical protein YP_002347005.1 2291211 D 214092 CDS YP_002347006.1 218929131 1174858 2291609..2292418 1 NC_003143.1 transcriptional regulator 2292418 1174858 YPO2020 Yersinia pestis CO92 transcriptional regulator YP_002347006.1 2291609 D 214092 CDS YP_002347007.1 218929132 1174859 2292514..2293368 1 NC_003143.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 2293368 kdsA 1174859 kdsA Yersinia pestis CO92 2-dehydro-3-deoxyphosphooctonate aldolase YP_002347007.1 2292514 D 214092 CDS YP_002347008.1 218929133 1174860 2293850..2294308 1 NC_003143.1 transposase for the IS1541 insertion element 2294308 tnp 1174860 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347008.1 2293850 D 214092 CDS YP_002347009.1 218929134 1174862 complement(2294928..2295710) 1 NC_003143.1 transposase/IS protein 2295710 1174862 YPO2025 Yersinia pestis CO92 transposase/IS protein YP_002347009.1 2294928 R 214092 CDS YP_002347010.1 218929135 1174863 complement(2295707..2296729) 1 NC_003143.1 transposase for insertion sequence IS100 2296729 y1093 1174863 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002347010.1 2295707 R 214092 CDS YP_002347012.1 218929137 1174866 complement(2299155..2300030) 1 NC_003143.1 hypothetical protein 2300030 1174866 YPO2028 Yersinia pestis CO92 hypothetical protein YP_002347012.1 2299155 R 214092 CDS YP_002347013.1 218929138 1174867 complement(2300331..2301413) 1 NC_003143.1 hypothetical protein 2301413 1174867 YPO2029 Yersinia pestis CO92 hypothetical protein YP_002347013.1 2300331 R 214092 CDS YP_002347014.1 218929139 1174868 complement(2301433..2302269) 1 NC_003143.1 binding-protein-dependent transporter membrane protein 2302269 1174868 YPO2030 Yersinia pestis CO92 binding-protein-dependent transporter membrane protein YP_002347014.1 2301433 R 214092 CDS YP_002347015.1 218929140 1174869 complement(2302266..2303132) 1 NC_003143.1 binding-protein-dependent transporter membrane protein 2303132 1174869 YPO2031 Yersinia pestis CO92 binding-protein-dependent transporter membrane protein YP_002347015.1 2302266 R 214092 CDS YP_002347016.1 218929141 1174871 2304034..2304492 1 NC_003143.1 transposase for the IS1541 insertion element 2304492 tnp 1174871 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347016.1 2304034 D 214092 CDS YP_002347017.1 218929142 1174872 2305121..2305951 1 NC_003143.1 hypothetical protein 2305951 1174872 YPO2035 Yersinia pestis CO92 hypothetical protein YP_002347017.1 2305121 D 214092 CDS YP_002347018.1 218929143 1174873 2305965..2307077 1 NC_003143.1 transcriptional regulator 2307077 1174873 YPO2036 Yersinia pestis CO92 transcriptional regulator YP_002347018.1 2305965 D 214092 CDS YP_002347019.1 218929144 1174875 2307712..2308449 1 NC_003143.1 hydrolase 2308449 1174875 YPO2037 Yersinia pestis CO92 hydrolase YP_002347019.1 2307712 D 214092 CDS YP_002347020.1 218929145 1174876 2308486..2309046 1 NC_003143.1 hypothetical protein 2309046 1174876 YPO2038 Yersinia pestis CO92 hypothetical protein YP_002347020.1 2308486 D 214092 CDS YP_002347021.1 218929146 1174877 complement(2309500..2310063) 1 NC_003143.1 hypothetical protein 2310063 1174877 YPO2039 Yersinia pestis CO92 hypothetical protein YP_002347021.1 2309500 R 214092 CDS YP_002347022.1 218929147 1174878 complement(2310458..2311663) 1 NC_003143.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 2311663 1174878 YPO2040 Yersinia pestis CO92 multidrug resistance protein MdtH YP_002347022.1 2310458 R 214092 CDS YP_002347023.1 218929148 1174879 2311957..2312541 1 NC_003143.1 ribosomal-protein-S5-alanine N-acetyltransferase 2312541 rimJ 1174879 rimJ Yersinia pestis CO92 ribosomal-protein-S5-alanine N-acetyltransferase YP_002347023.1 2311957 D 214092 CDS YP_002347024.1 218929149 1174880 2312549..2314159 1 NC_003143.1 oxidoreductase 2314159 1174880 YPO2042 Yersinia pestis CO92 oxidoreductase YP_002347024.1 2312549 D 214092 CDS YP_002347025.1 218929150 1174881 2314426..2315961 1 NC_003143.1 hypothetical protein 2315961 mviN 1174881 mviN Yersinia pestis CO92 hypothetical protein YP_002347025.1 2314426 D 214092 CDS YP_002347026.1 218929151 1174882 2316429..2318102 1 NC_003143.1 hemolysin activator protein 2318102 1174882 YPO2044 Yersinia pestis CO92 hemolysin activator protein YP_002347026.1 2316429 D 214092 CDS YP_002347027.1 218929152 1174883 2318132..2322862 1 NC_003143.1 hemolysin 2322862 1174883 YPO2045 Yersinia pestis CO92 hemolysin YP_002347027.1 2318132 D 214092 CDS YP_002347028.1 218929153 1174884 complement(2323093..2324823) 1 NC_003143.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2324823 argS 1174884 argS Yersinia pestis CO92 arginyl-tRNA synthetase YP_002347028.1 2323093 R 214092 CDS YP_002347029.1 218929154 1174885 2325446..2326021 1 NC_003143.1 hypothetical protein 2326021 1174885 YPO2047 Yersinia pestis CO92 hypothetical protein YP_002347029.1 2325446 D 214092 CDS YP_002347030.1 218929155 1174886 2326253..2327017 1 NC_003143.1 copper homeostasis protein CutC 2327017 cutC 1174886 cutC Yersinia pestis CO92 copper homeostasis protein CutC YP_002347030.1 2326253 D 214092 CDS YP_002347031.1 218929156 1174887 complement(2327210..2328181) 1 NC_003143.1 hypothetical protein 2328181 1174887 YPO2049 Yersinia pestis CO92 hypothetical protein YP_002347031.1 2327210 R 214092 CDS YP_002347032.1 218929157 1174888 complement(2328178..2328981) 1 NC_003143.1 hypothetical protein 2328981 1174888 YPO2050 Yersinia pestis CO92 hypothetical protein YP_002347032.1 2328178 R 214092 CDS YP_002347033.1 218929158 1174889 complement(2329172..2329567) 1 NC_003143.1 hypothetical protein 2329567 1174889 YPO2051 Yersinia pestis CO92 hypothetical protein YP_002347033.1 2329172 R 214092 CDS YP_002347034.1 218929159 1174890 complement(2329747..2330562) 1 NC_003143.1 hypothetical protein 2330562 1174890 YPO2052 Yersinia pestis CO92 hypothetical protein YP_002347034.1 2329747 R 214092 CDS YP_002347035.1 218929160 1174891 2331620..2333416 1 NC_003143.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 2333416 aspS 1174891 aspS Yersinia pestis CO92 aspartyl-tRNA synthetase YP_002347035.1 2331620 D 214092 CDS YP_002347036.1 218929161 1174892 2333416..2333859 1 NC_003143.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 2333859 ntpA 1174892 ntpA Yersinia pestis CO92 dATP pyrophosphohydrolase YP_002347036.1 2333416 D 214092 CDS YP_002347037.1 218929162 1174893 2333917..2334660 1 NC_003143.1 hypothetical protein 2334660 1174893 YPO2055 Yersinia pestis CO92 hypothetical protein YP_002347037.1 2333917 D 214092 CDS YP_002347038.1 218929163 1174894 2334869..2335390 1 NC_003143.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 2335390 ruvC 1174894 ruvC Yersinia pestis CO92 Holliday junction resolvase YP_002347038.1 2334869 D 214092 CDS YP_002347039.1 218929164 1174895 2335673..2336287 1 NC_003143.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 2336287 ruvA 1174895 ruvA Yersinia pestis CO92 Holliday junction DNA helicase RuvA YP_002347039.1 2335673 D 214092 CDS YP_002347040.1 218929165 1174896 2336449..2337453 1 NC_003143.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 2337453 ruvB 1174896 ruvB Yersinia pestis CO92 Holliday junction DNA helicase RuvB YP_002347040.1 2336449 D 214092 CDS YP_002347041.1 218929166 1174897 complement(2337508..2338293) 1 NC_003143.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 2338293 znuB 1174897 znuB Yersinia pestis CO92 high-affinity zinc transporter membrane protein YP_002347041.1 2337508 R 214092 CDS YP_002347042.1 218929167 1174898 complement(2338290..2339048) 1 NC_003143.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 2339048 znuC 1174898 znuC Yersinia pestis CO92 high-affinity zinc transporter ATPase YP_002347042.1 2338290 R 214092 CDS YP_002347043.1 218929168 1174899 2339124..2340080 1 NC_003143.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter substrate-binding protein 2340080 znuA 1174899 znuA Yersinia pestis CO92 high-affinity zinc transporter substrate-binding protein YP_002347043.1 2339124 D 214092 CDS YP_002347044.1 218929169 1174900 2340101..2341417 1 NC_003143.1 hypothetical protein 2341417 1174900 YPO2062 Yersinia pestis CO92 hypothetical protein YP_002347044.1 2340101 D 214092 CDS YP_002347045.1 218929170 1174901 2341684..2342646 1 NC_003143.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 2342646 msbB 1174901 msbB Yersinia pestis CO92 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_002347045.1 2341684 D 214092 CDS YP_002347046.1 218929171 1174902 complement(2342991..2344433) 1 NC_003143.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2344433 pykA 1174902 pykA Yersinia pestis CO92 pyruvate kinase YP_002347046.1 2342991 R 214092 CDS YP_002347047.1 218929172 1174903 complement(2344763..2345632) 1 NC_003143.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 2345632 hexR 1174903 hexR Yersinia pestis CO92 DNA-binding transcriptional regulator HexR YP_002347047.1 2344763 R 214092 CDS YP_002347048.1 218929173 1174904 2345994..2347469 1 NC_003143.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2347469 zwf 1174904 zwf Yersinia pestis CO92 glucose-6-phosphate 1-dehydrogenase YP_002347048.1 2345994 D 214092 CDS YP_002347049.1 218929174 1174905 2347711..2348352 1 NC_003143.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 2348352 eda 1174905 eda Yersinia pestis CO92 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002347049.1 2347711 D 214092 CDS YP_002347050.1 218929175 1174906 2349046..2349510 1 NC_003143.1 hypothetical protein 2349510 1174906 YPO2068 Yersinia pestis CO92 hypothetical protein YP_002347050.1 2349046 D 214092 CDS YP_002347051.1 218929176 1174907 2349530..2349826 1 NC_003143.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS; multidrug efflux system protein MdtI 2349826 1174907 YPO2069 Yersinia pestis CO92 multidrug efflux system protein MdtI YP_002347051.1 2349530 D 214092 CDS YP_002347052.1 218929177 1174908 complement(2349958..2350302) 1 NC_003143.1 hypothetical protein 2350302 1174908 YPO2070 Yersinia pestis CO92 hypothetical protein YP_002347052.1 2349958 R 214092 CDS YP_002347053.1 218929178 1174909 2350433..2352337 1 NC_003143.1 DEAD box family helicase 2352337 1174909 YPO2071 Yersinia pestis CO92 DEAD box family helicase YP_002347053.1 2350433 D 214092 CDS YP_002347054.1 218929179 1174910 2352409..2353107 1 NC_003143.1 hypothetical protein 2353107 1174910 YPO2072 Yersinia pestis CO92 hypothetical protein YP_002347054.1 2352409 D 214092 CDS YP_002347055.1 218929180 1174911 2353262..2353849 1 NC_003143.1 lipoprotein 2353849 1174911 YPO2073 Yersinia pestis CO92 lipoprotein YP_002347055.1 2353262 D 214092 CDS YP_002347056.1 218929181 1174912 2354492..2356180 1 NC_003143.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 2356180 fadD 1174912 fadD Yersinia pestis CO92 long-chain-fatty-acid--CoA ligase YP_002347056.1 2354492 D 214092 CDS YP_002347057.1 218929182 1174913 2356340..2357461 1 NC_003143.1 ribonuclease D 2357461 rnd 1174913 rnd Yersinia pestis CO92 ribonuclease D YP_002347057.1 2356340 D 214092 CDS YP_002347058.1 218929183 1174914 complement(2357698..2357967) 1 NC_003143.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 2357967 minE 1174914 minE Yersinia pestis CO92 cell division topological specificity factor MinE YP_002347058.1 2357698 R 214092 CDS YP_002347059.1 218929184 1174915 complement(2357971..2358783) 1 NC_003143.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 2358783 minD 1174915 minD Yersinia pestis CO92 cell division inhibitor MinD YP_002347059.1 2357971 R 214092 CDS YP_002347060.1 218929185 1174916 complement(2358808..2359494) 1 NC_003143.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 2359494 minC 1174916 minC Yersinia pestis CO92 septum formation inhibitor YP_002347060.1 2358808 R 214092 CDS YP_002347062.1 218929187 1174918 2360215..2360487 1 NC_003143.1 hypothetical protein 2360487 1174918 YPO2080 Yersinia pestis CO92 hypothetical protein YP_002347062.1 2360215 D 214092 CDS YP_002347063.1 218929188 1174919 2360628..2361713 1 NC_003143.1 lipoprotein 2361713 1174919 YPO2081 Yersinia pestis CO92 lipoprotein YP_002347063.1 2360628 D 214092 CDS YP_002347064.1 218929189 1174920 2361784..2362440 1 NC_003143.1 hypothetical protein 2362440 1174920 YPO2082 Yersinia pestis CO92 hypothetical protein YP_002347064.1 2361784 D 214092 CDS YP_002347065.1 218929190 1174921 2362543..2362989 1 NC_003143.1 hypothetical protein 2362989 1174921 YPO2083 Yersinia pestis CO92 hypothetical protein YP_002347065.1 2362543 D 214092 CDS YP_008479712.1 537470175 16744762 complement(2363016..2364254) 1 NC_003143.1 integrase 2364254 16744762 YOP2083 Yersinia pestis CO92 integrase YP_008479712.1 2363016 R 214092 CDS YP_002347066.1 218929191 1174923 2364324..2365346 1 NC_003143.1 transposase for insertion sequence IS100 2365346 y1093 1174923 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002347066.1 2364324 D 214092 CDS YP_002347067.1 218929192 1174924 2365343..2366125 1 NC_003143.1 transposase/IS protein 2366125 1174924 YPO2086 Yersinia pestis CO92 transposase/IS protein YP_002347067.1 2365343 D 214092 CDS YP_002347068.1 218929193 1174925 complement(2366293..2366553) 1 NC_003143.1 phage excisionase 2366553 1174925 YPO2087 Yersinia pestis CO92 phage excisionase YP_002347068.1 2366293 R 214092 CDS YP_002347070.1 218929195 1174927 complement(2366853..2367497) 1 NC_003143.1 methyltransferase 2367497 1174927 YPO2088 Yersinia pestis CO92 methyltransferase YP_002347070.1 2366853 R 214092 CDS YP_002347071.1 218929196 1174928 2367596..2368024 1 NC_003143.1 hypothetical protein 2368024 ninB 1174928 ninB Yersinia pestis CO92 hypothetical protein YP_002347071.1 2367596 D 214092 CDS YP_002347072.1 218929197 1174929 2368098..2368703 1 NC_003143.1 hypothetical protein 2368703 1174929 YPO2090 Yersinia pestis CO92 hypothetical protein YP_002347072.1 2368098 D 214092 CDS YP_002347073.1 218929198 1174930 2368704..2369093 1 NC_003143.1 phage antitermination protein 2369093 1174930 YPO2091 Yersinia pestis CO92 phage antitermination protein YP_002347073.1 2368704 D 214092 CDS YP_002347075.1 218929200 1174932 2369364..2369927 1 NC_003143.1 hypothetical protein 2369927 1174932 YPO2093 Yersinia pestis CO92 hypothetical protein YP_002347075.1 2369364 D 214092 CDS YP_002347077.1 218929202 1174934 2370351..2370560 1 NC_003143.1 hypothetical protein 2370560 1174934 YPO2095 Yersinia pestis CO92 hypothetical protein YP_002347077.1 2370351 D 214092 CDS YP_002347078.1 218929203 1174935 complement(2370557..2370832) 1 NC_003143.1 hypothetical protein 2370832 1174935 YPO2096 Yersinia pestis CO92 hypothetical protein YP_002347078.1 2370557 R 214092 CDS YP_002347080.1 218929205 1174937 2371306..2371818 1 NC_003143.1 phage lysozyme 2371818 1174937 YPO2098 Yersinia pestis CO92 phage lysozyme YP_002347080.1 2371306 D 214092 CDS YP_002347081.1 218929206 1174938 2371803..2372261 1 NC_003143.1 prophage endopeptidase 2372261 rzpR 1174938 rzpR Yersinia pestis CO92 prophage endopeptidase YP_002347081.1 2371803 D 214092 CDS YP_002347082.1 218929207 1174939 2372723..2373520 1 NC_003143.1 phage regulatory protein 2373520 1174939 YPO2100 Yersinia pestis CO92 phage regulatory protein YP_002347082.1 2372723 D 214092 CDS YP_002347083.1 218929208 1174940 2373977..2374612 1 NC_003143.1 hypothetical protein 2374612 1174940 YPO2101 Yersinia pestis CO92 hypothetical protein YP_002347083.1 2373977 D 214092 CDS YP_002347084.1 218929209 1174941 2374643..2375092 1 NC_003143.1 hypothetical protein 2375092 1174941 YPO2102 Yersinia pestis CO92 hypothetical protein YP_002347084.1 2374643 D 214092 CDS YP_002347085.1 218929210 1174943 2375728..2376936 1 NC_003143.1 transposase for the IS285 insertion element 2376936 y1062 1174943 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002347085.1 2375728 D 214092 CDS YP_008479713.1 537470176 16744763 2376941..2377915 1 NC_003143.1 hypothetical protein 2377915 16744763 YPO2104a Yersinia pestis CO92 hypothetical protein YP_008479713.1 2376941 D 214092 CDS YP_002347086.1 218929211 1174945 2379304..2380416 1 NC_003143.1 hypothetical protein 2380416 1174945 YPO2108 Yersinia pestis CO92 hypothetical protein YP_002347086.1 2379304 D 214092 CDS YP_002347087.1 218929212 1174946 2380538..2381311 1 NC_003143.1 hypothetical protein 2381311 1174946 YPO2109 Yersinia pestis CO92 hypothetical protein YP_002347087.1 2380538 D 214092 CDS YP_002347088.1 218929213 1174947 2381325..2382530 1 NC_003143.1 hypothetical protein 2382530 1174947 YPO2110 Yersinia pestis CO92 hypothetical protein YP_002347088.1 2381325 D 214092 CDS YP_002347089.1 218929214 1174948 2382530..2383060 1 NC_003143.1 hypothetical protein 2383060 1174948 YPO2111 Yersinia pestis CO92 hypothetical protein YP_002347089.1 2382530 D 214092 CDS YP_002347090.1 218929215 1174949 2383057..2383311 1 NC_003143.1 hypothetical protein 2383311 1174949 YPO2112 Yersinia pestis CO92 hypothetical protein YP_002347090.1 2383057 D 214092 CDS YP_002347091.1 218929216 1174950 2383313..2383663 1 NC_003143.1 hypothetical protein 2383663 1174950 YPO2113 Yersinia pestis CO92 hypothetical protein YP_002347091.1 2383313 D 214092 CDS YP_002347092.1 218929217 1174951 2383665..2384249 1 NC_003143.1 hypothetical protein 2384249 1174951 YPO2114 Yersinia pestis CO92 hypothetical protein YP_002347092.1 2383665 D 214092 CDS YP_002347093.1 218929218 1174952 2384246..2384653 1 NC_003143.1 hypothetical protein 2384653 1174952 YPO2115 Yersinia pestis CO92 hypothetical protein YP_002347093.1 2384246 D 214092 CDS YP_002347094.1 218929219 1174953 2384719..2385639 1 NC_003143.1 hypothetical protein 2385639 1174953 YPO2116 Yersinia pestis CO92 hypothetical protein YP_002347094.1 2384719 D 214092 CDS YP_002347095.1 218929220 1174954 2385652..2385963 1 NC_003143.1 hypothetical protein 2385963 1174954 YPO2117 Yersinia pestis CO92 hypothetical protein YP_002347095.1 2385652 D 214092 CDS YP_002347096.1 218929221 1174955 2386050..2386271 1 NC_003143.1 hypothetical protein 2386271 1174955 YPO2118 Yersinia pestis CO92 hypothetical protein YP_002347096.1 2386050 D 214092 CDS YP_002347097.1 218929222 1174956 2386272..2389775 1 NC_003143.1 phage tail protein 2389775 1174956 YPO2119 Yersinia pestis CO92 phage tail protein YP_002347097.1 2386272 D 214092 CDS YP_002347098.1 218929223 1174957 2389778..2390119 1 NC_003143.1 hypothetical protein 2390119 1174957 YPO2120 Yersinia pestis CO92 hypothetical protein YP_002347098.1 2389778 D 214092 CDS YP_002347099.1 218929224 1174958 2390424..2390882 1 NC_003143.1 transposase for the IS1541 insertion element 2390882 tnp 1174958 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347099.1 2390424 D 214092 CDS YP_002347100.1 218929225 1174959 2391003..2391755 1 NC_003143.1 hypothetical protein 2391755 1174959 YPO2122 Yersinia pestis CO92 hypothetical protein YP_002347100.1 2391003 D 214092 CDS YP_002347101.1 218929226 1174960 2391758..2392468 1 NC_003143.1 phage minor tail protein 2392468 1174960 YPO2123 Yersinia pestis CO92 phage minor tail protein YP_002347101.1 2391758 D 214092 CDS YP_002347102.1 218929227 1174961 2392729..2393361 1 NC_003143.1 hypothetical protein 2393361 1174961 YPO2124 Yersinia pestis CO92 hypothetical protein YP_002347102.1 2392729 D 214092 CDS YP_002347104.1 218929229 1174963 2394149..2395243 1 NC_003143.1 hypothetical protein 2395243 1174963 YPO2126 Yersinia pestis CO92 hypothetical protein YP_002347104.1 2394149 D 214092 CDS YP_002347105.1 218929230 1174964 2395342..2395893 1 NC_003143.1 phage-like membrane protein 2395893 1174964 YPO2127 Yersinia pestis CO92 phage-like membrane protein YP_002347105.1 2395342 D 214092 CDS YP_002347106.1 218929231 1174965 2395901..2396251 1 NC_003143.1 phage-like lipoprotein 2396251 1174965 YPO2128 Yersinia pestis CO92 phage-like lipoprotein YP_002347106.1 2395901 D 214092 CDS YP_002347107.1 218929232 1174966 2396307..2396927 1 NC_003143.1 phage tail assembly protein 2396927 1174966 YPO2129 Yersinia pestis CO92 phage tail assembly protein YP_002347107.1 2396307 D 214092 CDS YP_002347109.1 218929234 1174968 2397499..2400702 1 NC_003143.1 phage host specificity protein 2400702 1174968 YPO2131 Yersinia pestis CO92 phage host specificity protein YP_002347109.1 2397499 D 214092 CDS YP_002347110.1 218929235 1174969 2400702..2401700 1 NC_003143.1 hypothetical protein 2401700 1174969 YPO2132 Yersinia pestis CO92 hypothetical protein YP_002347110.1 2400702 D 214092 CDS YP_002347111.1 218929236 1174970 2401717..2402634 1 NC_003143.1 hypothetical protein 2402634 1174970 YPO2133 Yersinia pestis CO92 hypothetical protein YP_002347111.1 2401717 D 214092 CDS YP_002347112.1 218929237 1174971 2402645..2403064 1 NC_003143.1 phage tail fiber assembly protein 2403064 1174971 YPO2134 Yersinia pestis CO92 phage tail fiber assembly protein YP_002347112.1 2402645 D 214092 CDS YP_002347113.1 218929238 1174972 2403061..2403216 1 NC_003143.1 hypothetical protein 2403216 1174972 YPO2135 Yersinia pestis CO92 hypothetical protein YP_002347113.1 2403061 D 214092 CDS YP_002347114.1 218929239 1174973 complement(2403285..2404493) 1 NC_003143.1 transposase for the IS285 insertion element 2404493 y1062 1174973 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002347114.1 2403285 R 214092 CDS YP_002347115.1 218929240 1174974 complement(2404798..2405970) 1 NC_003143.1 hypothetical protein 2405970 1174974 YPO2137 Yersinia pestis CO92 hypothetical protein YP_002347115.1 2404798 R 214092 CDS YP_002347116.1 218929241 1174975 complement(2405974..2407173) 1 NC_003143.1 aminotransferase 2407173 1174975 YPO2138 Yersinia pestis CO92 aminotransferase YP_002347116.1 2405974 R 214092 CDS YP_002347117.1 218929242 1174976 complement(2407190..2407930) 1 NC_003143.1 hypothetical protein 2407930 1174976 YPO2139 Yersinia pestis CO92 hypothetical protein YP_002347117.1 2407190 R 214092 CDS YP_002347118.1 218929243 1174977 2409022..2409378 1 NC_003143.1 hypothetical protein 2409378 1174977 YPO2140 Yersinia pestis CO92 hypothetical protein YP_002347118.1 2409022 D 214092 CDS YP_002347119.1 218929244 1174978 complement(2409795..2410325) 1 NC_003143.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 2410325 dsbB 1174978 dsbB Yersinia pestis CO92 disulfide bond formation protein B YP_002347119.1 2409795 R 214092 CDS YP_002347120.1 218929245 1174979 complement(2410561..2412135) 1 NC_003143.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 2412135 nhaB 1174979 nhaB Yersinia pestis CO92 sodium/proton antiporter YP_002347120.1 2410561 R 214092 CDS YP_002347121.1 218929246 1174980 2412379..2413098 1 NC_003143.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 2413098 fadR 1174980 fadR Yersinia pestis CO92 fatty acid metabolism regulator YP_002347121.1 2412379 D 214092 CDS YP_002347122.1 218929247 1174981 complement(2413316..2414851) 1 NC_003143.1 SpoVR family protein 2414851 1174981 YPO2145 Yersinia pestis CO92 SpoVR family protein YP_002347122.1 2413316 R 214092 CDS YP_002347123.1 218929248 1174982 2415316..2416620 1 NC_003143.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 2416620 dadA 1174982 dadA Yersinia pestis CO92 D-amino acid dehydrogenase small subunit YP_002347123.1 2415316 D 214092 CDS YP_002347124.1 218929249 1174983 complement(2416636..2417838) 1 NC_003143.1 multidrug resistance protein 2417838 1174983 YPO2148 Yersinia pestis CO92 multidrug resistance protein YP_002347124.1 2416636 R 214092 CDS YP_002347125.1 218929250 1174984 complement(2418103..2418972) 1 NC_003143.1 hypothetical protein 2418972 1174984 YPO2149 Yersinia pestis CO92 hypothetical protein YP_002347125.1 2418103 R 214092 CDS YP_002347126.1 218929251 1174985 2419170..2420075 1 NC_003143.1 LysR family transcriptional regulator 2420075 1174985 YPO2150 Yersinia pestis CO92 LysR family transcriptional regulator YP_002347126.1 2419170 D 214092 CDS YP_002347127.1 218929252 1174986 complement(2420110..2421231) 1 NC_003143.1 hypothetical protein 2421231 1174986 YPO2151 Yersinia pestis CO92 hypothetical protein YP_002347127.1 2420110 R 214092 CDS YP_002347128.1 218929253 1174987 complement(2421336..2422610) 1 NC_003143.1 hypothetical protein 2422610 1174987 YPO2152 Yersinia pestis CO92 hypothetical protein YP_002347128.1 2421336 R 214092 CDS YP_002347129.1 218929254 1174988 complement(2422760..2424694) 1 NC_003143.1 hypothetical protein 2424694 1174988 YPO2153 Yersinia pestis CO92 hypothetical protein YP_002347129.1 2422760 R 214092 CDS YP_002347130.1 218929255 1174989 2425117..2425887 1 NC_003143.1 hypothetical protein 2425887 1174989 YPO2155 Yersinia pestis CO92 hypothetical protein YP_002347130.1 2425117 D 214092 CDS YP_002347131.1 218929256 1174990 complement(2425960..2426835) 1 NC_003143.1 hypothetical protein 2426835 1174990 YPO2156 Yersinia pestis CO92 hypothetical protein YP_002347131.1 2425960 R 214092 CDS YP_002347132.1 218929257 1174991 complement(2427149..2428153) 1 NC_003143.1 glyceraldehyde 3-phosphate dehydrogenase A 2428153 gapA 1174991 gapA Yersinia pestis CO92 glyceraldehyde 3-phosphate dehydrogenase A YP_002347132.1 2427149 R 214092 CDS YP_002347133.1 218929258 1174992 2428492..2428905 1 NC_003143.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 2428905 1174992 YPO2158 Yersinia pestis CO92 methionine sulfoxide reductase B YP_002347133.1 2428492 D 214092 CDS YP_002347134.1 218929259 1174993 2428976..2429248 1 NC_003143.1 hypothetical protein 2429248 1174993 YPO2159 Yersinia pestis CO92 hypothetical protein YP_002347134.1 2428976 D 214092 CDS YP_002347135.1 218929260 1174994 complement(2429382..2430029) 1 NC_003143.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 2430029 pncA 1174994 pncA Yersinia pestis CO92 nicotinamidase/pyrazinamidase YP_002347135.1 2429382 R 214092 CDS YP_002347136.1 218929261 1174995 complement(2430044..2431060) 1 NC_003143.1 converts asparagine to aspartate and ammonia; cytoplasmic asparaginase I 2431060 ansA 1174995 ansA Yersinia pestis CO92 cytoplasmic asparaginase I YP_002347136.1 2430044 R 214092 CDS YP_002347137.1 218929262 1174996 complement(2431177..2433027) 1 NC_003143.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 2433027 sppA 1174996 sppA Yersinia pestis CO92 protease 4 YP_002347137.1 2431177 R 214092 CDS YP_002347138.1 218929263 1174997 2433190..2433741 1 NC_003143.1 hypothetical protein 2433741 1174997 YPO2163 Yersinia pestis CO92 hypothetical protein YP_002347138.1 2433190 D 214092 CDS YP_002347139.1 218929264 1174998 2433966..2435012 1 NC_003143.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 2435012 selD 1174998 selD Yersinia pestis CO92 selenophosphate synthetase YP_002347139.1 2433966 D 214092 CDS YP_002347140.1 218929265 1174999 2435071..2436999 1 NC_003143.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 2436999 topB 1174999 topB Yersinia pestis CO92 DNA topoisomerase III YP_002347140.1 2435071 D 214092 CDS YP_002347141.1 218929266 1175000 2436996..2437286 1 NC_003143.1 hypothetical protein 2437286 1175000 YPO2166 Yersinia pestis CO92 hypothetical protein YP_002347141.1 2436996 D 214092 CDS YP_002347142.1 218929267 1175001 complement(2437299..2437685) 1 NC_003143.1 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 2437685 nudG 1175001 nudG Yersinia pestis CO92 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_002347142.1 2437299 R 214092 CDS YP_002347143.1 218929268 1175002 complement(2437783..2438589) 1 NC_003143.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 2438589 xthA 1175002 xthA Yersinia pestis CO92 exonuclease III YP_002347143.1 2437783 R 214092 CDS YP_002347144.1 218929269 1175003 2439399..2440259 1 NC_003143.1 LysR family transcriptional regulator 2440259 1175003 YPO2169 Yersinia pestis CO92 LysR family transcriptional regulator YP_002347144.1 2439399 D 214092 CDS YP_002347145.1 218929270 1175006 2441131..2442339 1 NC_003143.1 transposase for the IS285 insertion element 2442339 y1062 1175006 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002347145.1 2441131 D 214092 CDS YP_008479714.1 537470177 1175005 complement(2442302..2443171) 1 NC_003143.1 formyltetrahydrofolate deformylase 2443171 1175005 YPO2171 Yersinia pestis CO92 formyltetrahydrofolate deformylase YP_008479714.1 2442302 R 214092 CDS YP_002347146.1 218929271 1175007 complement(2443255..2443719) 1 NC_003143.1 hypothetical protein 2443719 1175007 YPO2172 Yersinia pestis CO92 hypothetical protein YP_002347146.1 2443255 R 214092 CDS YP_002347147.1 218929272 1175008 2445053..2446069 1 NC_003143.1 response regulator of RpoS 2446069 1175008 YPO2173 Yersinia pestis CO92 response regulator of RpoS YP_002347147.1 2445053 D 214092 CDS YP_002347148.1 218929273 1175009 2446376..2447722 1 NC_003143.1 nucleotide sugar dehydrogenase 2447722 1175009 YPO2174 Yersinia pestis CO92 nucleotide sugar dehydrogenase YP_002347148.1 2446376 D 214092 CDS YP_002347149.1 218929274 1175010 complement(2448157..2448555) 1 NC_003143.1 global DNA-binding transcriptional dual regulator H-NS 2448555 hns 1175010 hns Yersinia pestis CO92 global DNA-binding transcriptional dual regulator H-NS YP_002347149.1 2448157 R 214092 CDS YP_002347150.1 218929275 1175011 2449305..2449895 1 NC_003143.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 2449895 tdk 1175011 tdk Yersinia pestis CO92 thymidine kinase YP_002347150.1 2449305 D 214092 CDS YP_002347151.1 218929276 1175012 complement(2450264..2451046) 1 NC_003143.1 transposase/IS protein 2451046 1175012 YPO2177 Yersinia pestis CO92 transposase/IS protein YP_002347151.1 2450264 R 214092 CDS YP_002347152.1 218929277 1175013 complement(2451043..2452065) 1 NC_003143.1 transposase for insertion sequence IS100 2452065 y1093 1175013 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002347152.1 2451043 R 214092 CDS YP_002347153.1 218929278 1175014 complement(2452605..2455280) 1 NC_003143.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase 2455280 adhE 1175014 adhE Yersinia pestis CO92 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002347153.1 2452605 R 214092 CDS YP_002347154.1 218929279 1175015 2456087..2456731 1 NC_003143.1 hypothetical protein 2456731 1175015 YPO2181 Yersinia pestis CO92 hypothetical protein YP_002347154.1 2456087 D 214092 CDS YP_002347155.1 218929280 1175016 2457569..2459206 1 NC_003143.1 periplasmic oligopeptide-binding protein 2459206 oppA 1175016 oppA Yersinia pestis CO92 periplasmic oligopeptide-binding protein YP_002347155.1 2457569 D 214092 CDS YP_002347156.1 218929281 1175017 2459293..2460213 1 NC_003143.1 oligopeptide transporter permease 2460213 oppB 1175017 oppB Yersinia pestis CO92 oligopeptide transporter permease YP_002347156.1 2459293 D 214092 CDS YP_002347157.1 218929282 1175018 2460232..2461137 1 NC_003143.1 oligopeptide transport system permease 2461137 oppC 1175018 oppC Yersinia pestis CO92 oligopeptide transport system permease YP_002347157.1 2460232 D 214092 CDS YP_002347158.1 218929283 1175019 2461149..2462150 1 NC_003143.1 oligopeptide transporter ATP-binding component 2462150 oppD 1175019 oppD Yersinia pestis CO92 oligopeptide transporter ATP-binding component YP_002347158.1 2461149 D 214092 CDS YP_002347159.1 218929284 1175020 2462147..2463148 1 NC_003143.1 oligopeptide transport ATP-binding protein 2463148 oppF 1175020 oppF Yersinia pestis CO92 oligopeptide transport ATP-binding protein YP_002347159.1 2462147 D 214092 CDS YP_008479715.1 537470178 16744764 2463709..2463924 1 NC_003143.1 hypothetical protein 2463924 16744764 YPO2186a Yersinia pestis CO92 hypothetical protein YP_008479715.1 2463709 D 214092 CDS YP_002347160.1 218929285 1175021 complement(2464223..2464546) 1 NC_003143.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 2464546 1175021 YPO2187 Yersinia pestis CO92 dsDNA-mimic protein YP_002347160.1 2464223 R 214092 CDS YP_002347161.1 218929286 1175022 complement(2464711..2466171) 1 NC_003143.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 2466171 cls 1175022 cls Yersinia pestis CO92 cardiolipin synthetase YP_002347161.1 2464711 R 214092 CDS YP_002347162.1 218929287 1175023 complement(2466240..2466488) 1 NC_003143.1 No significant database matches. Similar to CDS YPO2920 (8s aa) E(): 2.5e-23, 95.1% identity in 61 aa overlap; hypothetical protein 2466488 1175023 YPO2189 Yersinia pestis CO92 hypothetical protein YP_002347162.1 2466240 R 214092 CDS YP_002347163.1 218929288 1175024 2467211..2467750 1 NC_003143.1 attachment invasion locus protein 2467750 ail 1175024 ail Yersinia pestis CO92 attachment invasion locus protein YP_002347163.1 2467211 D 214092 CDS YP_002347164.1 218929289 1175025 2467971..2468234 1 NC_003143.1 No significant database hits; hypothetical protein 2468234 1175025 YPO2191 Yersinia pestis CO92 hypothetical protein YP_002347164.1 2467971 D 214092 CDS YP_002347165.1 218929290 1175026 complement(2468818..2469114) 1 NC_003143.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 2469114 1175026 YPO2192 Yersinia pestis CO92 hypothetical protein YP_002347165.1 2468818 R 214092 CDS YP_002347166.1 218929291 1175027 2469415..2470173 1 NC_003143.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transport protein TonB 2470173 tonB 1175027 tonB Yersinia pestis CO92 transport protein TonB YP_002347166.1 2469415 D 214092 CDS YP_002347167.1 218929292 1175028 complement(2470209..2471417) 1 NC_003143.1 transposase for the IS285 insertion element 2471417 y1062 1175028 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002347167.1 2470209 R 214092 CDS YP_002347168.1 218929293 1175029 complement(2471565..2472014) 1 NC_003143.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 2472014 1175029 YPO2195 Yersinia pestis CO92 acyl-CoA thioester hydrolase YP_002347168.1 2471565 R 214092 CDS YP_002347169.1 218929294 1175030 complement(2472094..2472636) 1 NC_003143.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 2472636 ispZ 1175030 ispZ Yersinia pestis CO92 intracellular septation protein A YP_002347169.1 2472094 R 214092 CDS YP_002347170.1 218929295 1175032 complement(2474722..2475492) 1 NC_003143.1 hypothetical protein 2475492 1175032 YPO2199 Yersinia pestis CO92 hypothetical protein YP_002347170.1 2474722 R 214092 CDS YP_002347171.1 218929296 1175033 2475654..2475869 1 NC_003143.1 No significant database hits; hypothetical protein 2475869 1175033 YPO2200 Yersinia pestis CO92 hypothetical protein YP_002347171.1 2475654 D 214092 CDS YP_002347172.1 218929297 1175034 2475978..2476613 1 NC_003143.1 receptor for colicin S4; outer membrane protein W 2476613 ompW 1175034 ompW Yersinia pestis CO92 outer membrane protein W YP_002347172.1 2475978 D 214092 CDS YP_002347173.1 218929298 1175035 complement(2476760..2477074) 1 NC_003143.1 lipoprotein 2477074 1175035 YPO2202 Yersinia pestis CO92 lipoprotein YP_002347173.1 2476760 R 214092 CDS YP_002347174.1 218929299 1175036 complement(2477417..2478223) 1 NC_003143.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 2478223 trpA 1175036 trpA Yersinia pestis CO92 tryptophan synthase subunit alpha YP_002347174.1 2477417 R 214092 CDS YP_002347175.1 218929300 1175037 complement(2478223..2479413) 1 NC_003143.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 2479413 trpB 1175037 trpB Yersinia pestis CO92 tryptophan synthase subunit beta YP_002347175.1 2478223 R 214092 CDS YP_002347176.1 218929301 1175038 complement(2479570..2480997) 1 NC_003143.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 2480997 trpC 1175038 trpC Yersinia pestis CO92 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_002347176.1 2479570 R 214092 CDS YP_002347177.1 218929302 1175039 complement(2481001..2481999) 1 NC_003143.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 2481999 trpD 1175039 trpD Yersinia pestis CO92 anthranilate phosphoribosyltransferase YP_002347177.1 2481001 R 214092 CDS YP_002347178.1 218929303 1175040 complement(2482014..2482592) 1 NC_003143.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 2482592 trpG 1175040 trpG Yersinia pestis CO92 anthranilate synthase component II YP_002347178.1 2482014 R 214092 CDS YP_002347179.1 218929304 1175041 complement(2482592..2484157) 1 NC_003143.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 2484157 trpE 1175041 trpE Yersinia pestis CO92 anthranilate synthase component I YP_002347179.1 2482592 R 214092 CDS YP_002347180.1 218929305 1175042 complement(2484273..2484335) 1 NC_003143.1 trp operon leader peptide 2484335 1175042 YPO2209 Yersinia pestis CO92 trp operon leader peptide YP_002347180.1 2484273 R 214092 CDS YP_002347181.1 218929306 1175043 complement(2484364..2484492) 1 NC_003143.1 No significant database hits; hypothetical protein 2484492 1175043 YPO2210 Yersinia pestis CO92 hypothetical protein YP_002347181.1 2484364 R 214092 CDS YP_002347182.1 218929307 1175044 2484609..2485508 1 NC_003143.1 hypothetical protein 2485508 trpH 1175044 trpH Yersinia pestis CO92 hypothetical protein YP_002347182.1 2484609 D 214092 CDS YP_002347183.1 218929308 1175045 2485525..2486145 1 NC_003143.1 hypothetical protein 2486145 1175045 YPO2212 Yersinia pestis CO92 hypothetical protein YP_002347183.1 2485525 D 214092 CDS YP_002347184.1 218929309 1175046 2486492..2487526 1 NC_003143.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 2487526 1175046 YPO2213 Yersinia pestis CO92 23S rRNA pseudouridylate synthase B YP_002347184.1 2486492 D 214092 CDS YP_002347185.1 218929310 1175047 complement(2487649..2488239) 1 NC_003143.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 2488239 btuR 1175047 btuR Yersinia pestis CO92 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_002347185.1 2487649 R 214092 CDS YP_002347186.1 218929311 1175048 complement(2488256..2489017) 1 NC_003143.1 short chain dehydrogenase 2489017 1175048 YPO2215 Yersinia pestis CO92 short chain dehydrogenase YP_002347186.1 2488256 R 214092 CDS YP_002347187.1 218929312 1175049 2489189..2490235 1 NC_003143.1 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 2490235 sohB 1175049 sohB Yersinia pestis CO92 periplasmic protease YP_002347187.1 2489189 D 214092 CDS YP_002347188.1 218929313 1175050 complement(2490354..2490605) 1 NC_003143.1 hypothetical protein 2490605 1175050 YPO2217 Yersinia pestis CO92 hypothetical protein YP_002347188.1 2490354 R 214092 CDS YP_002347189.1 218929314 1175051 2490623..2490997 1 NC_003143.1 Doubtful CDS. No significant database hits; hypothetical protein 2490997 1175051 YPO2217a Yersinia pestis CO92 hypothetical protein YP_002347189.1 2490623 D 214092 CDS YP_002347190.1 218929315 1175052 2491024..2493639 1 NC_003143.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 2493639 topA 1175052 topA Yersinia pestis CO92 DNA topoisomerase I YP_002347190.1 2491024 D 214092 CDS YP_002347191.1 218929316 1175053 2494036..2495010 1 NC_003143.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 2495010 cysB 1175053 cysB Yersinia pestis CO92 transcriptional regulator CysB YP_002347191.1 2494036 D 214092 CDS YP_002347192.1 218929317 1175054 2495346..2496203 1 NC_003143.1 No significant database hits; hypothetical protein 2496203 1175054 YPO2220 Yersinia pestis CO92 hypothetical protein YP_002347192.1 2495346 D 214092 CDS YP_002347193.1 218929318 1175055 2496567..2499239 1 NC_003143.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 2499239 acnA 1175055 acnA Yersinia pestis CO92 aconitate hydratase YP_002347193.1 2496567 D 214092 CDS YP_002347194.1 218929319 1175056 complement(2499403..2499993) 1 NC_003143.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 2499993 ribA 1175056 ribA Yersinia pestis CO92 GTP cyclohydrolase II YP_002347194.1 2499403 R 214092 CDS YP_002347195.1 218929320 1175057 2500499..2501260 1 NC_003143.1 phosphatidylglycerophosphatase B 2501260 pgpB 1175057 pgpB Yersinia pestis CO92 phosphatidylglycerophosphatase B YP_002347195.1 2500499 D 214092 CDS YP_002347196.1 218929321 1175058 2501429..2501740 1 NC_003143.1 hypothetical protein 2501740 1175058 YPO2224 Yersinia pestis CO92 hypothetical protein YP_002347196.1 2501429 D 214092 CDS YP_002347197.1 218929322 1175059 2501747..2502916 1 NC_003143.1 hypothetical protein 2502916 1175059 YPO2225 Yersinia pestis CO92 hypothetical protein YP_002347197.1 2501747 D 214092 CDS YP_002347198.1 218929323 1175060 complement(2503038..2503340) 1 NC_003143.1 No significant database hits; hypothetical protein 2503340 1175060 YPO2226 Yersinia pestis CO92 hypothetical protein YP_002347198.1 2503038 R 214092 CDS YP_002347199.1 218929324 1175061 2503807..2504544 1 NC_003143.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2504544 pyrF 1175061 pyrF Yersinia pestis CO92 orotidine 5'-phosphate decarboxylase YP_002347199.1 2503807 D 214092 CDS YP_002347200.1 218929325 1175062 2504544..2504870 1 NC_003143.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 2504870 1175062 YPO2228 Yersinia pestis CO92 translation initiation factor Sui1 YP_002347200.1 2504544 D 214092 CDS YP_002347201.1 218929326 1175063 complement(2505108..2505323) 1 NC_003143.1 lipoprotein 2505323 osmB 1175063 osmB Yersinia pestis CO92 lipoprotein YP_002347201.1 2505108 R 214092 CDS YP_002347202.1 218929327 1175064 2505803..2506498 1 NC_003143.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 2506498 araD 1175064 araD Yersinia pestis CO92 L-ribulose-5-phosphate 4-epimerase YP_002347202.1 2505803 D 214092 CDS YP_002347203.1 218929328 1175065 complement(2506527..2506775) 1 NC_003143.1 No significant database hits; hypothetical protein 2506775 1175065 YPO2231 Yersinia pestis CO92 hypothetical protein YP_002347203.1 2506527 R 214092 CDS YP_002347204.1 218929329 1175066 2507109..2507774 1 NC_003143.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 2507774 mipB 1175066 mipB Yersinia pestis CO92 fructose-6-phosphate aldolase YP_002347204.1 2507109 D 214092 CDS YP_002347205.1 218929330 1175067 complement(2507891..2508196) 1 NC_003143.1 hypothetical protein 2508196 1175067 YPO2233 Yersinia pestis CO92 hypothetical protein YP_002347205.1 2507891 R 214092 CDS YP_002347206.1 218929331 1175068 complement(2508189..2510255) 1 NC_003143.1 carbon starvation protein A 2510255 cstA 1175068 cstA Yersinia pestis CO92 carbon starvation protein A YP_002347206.1 2508189 R 214092 CDS YP_002347207.1 218929332 1175069 complement(2510605..2512539) 1 NC_003143.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 2512539 rnb 1175069 rnb Yersinia pestis CO92 exoribonuclease II YP_002347207.1 2510605 R 214092 CDS YP_002347208.1 218929333 1175070 2513188..2514498 1 NC_003143.1 hypothetical protein 2514498 1175070 YPO2237 Yersinia pestis CO92 hypothetical protein YP_002347208.1 2513188 D 214092 CDS YP_002347209.1 218929334 1175071 2514533..2515534 1 NC_003143.1 hypothetical protein 2515534 1175071 YPO2238 Yersinia pestis CO92 hypothetical protein YP_002347209.1 2514533 D 214092 CDS YP_002347210.1 218929335 1175072 complement(2515717..2516358) 1 NC_003143.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 2516358 nth 1175072 nth Yersinia pestis CO92 endonuclease III YP_002347210.1 2515717 R 214092 CDS YP_002347211.1 218929336 1175073 complement(2516355..2517056) 1 NC_003143.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex RsxE subunit 2517056 1175073 YPO2240 Yersinia pestis CO92 electron transport complex RsxE subunit YP_002347211.1 2516355 R 214092 CDS YP_002347212.1 218929337 1175074 complement(2517053..2517682) 1 NC_003143.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 2517682 1175074 YPO2241 Yersinia pestis CO92 electron transport complex protein RnfG YP_002347212.1 2517053 R 214092 CDS YP_002347213.1 218929338 1175075 complement(2517692..2518747) 1 NC_003143.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 2518747 rnfD 1175075 rnfD Yersinia pestis CO92 electron transport complex protein RnfD YP_002347213.1 2517692 R 214092 CDS YP_002347214.1 218929339 1175076 2519275..2520168 1 NC_003143.1 AraC family transcriptional regulator 2520168 1175076 YPO2243 Yersinia pestis CO92 AraC family transcriptional regulator YP_002347214.1 2519275 D 214092 CDS YP_002347215.1 218929340 1175077 complement(2520273..2522135) 1 NC_003143.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 2522135 1175077 YPO2244 Yersinia pestis CO92 electron transport complex protein RnfC YP_002347215.1 2520273 R 214092 CDS YP_002347216.1 218929341 1175078 complement(2522185..2522751) 1 NC_003143.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 2522751 1175078 YPO2245 Yersinia pestis CO92 electron transport complex protein RnfB YP_002347216.1 2522185 R 214092 CDS YP_002347217.1 218929342 1175079 complement(2522751..2523332) 1 NC_003143.1 Na(+)-translocating NADH-quinone reductase subunit E 2523332 1175079 YPO2246 Yersinia pestis CO92 Na(+)-translocating NADH-quinone reductase subunit E YP_002347217.1 2522751 R 214092 CDS YP_002347218.1 218929343 1175080 complement(2523460..2523903) 1 NC_003143.1 hypothetical protein 2523903 1175080 YPO2247 Yersinia pestis CO92 hypothetical protein YP_002347218.1 2523460 R 214092 CDS YP_002347219.1 218929344 1175083 2527832..2529970 1 NC_003143.1 toxin transport protein 2529970 1175083 YPO2252 Yersinia pestis CO92 toxin transport protein YP_002347219.1 2527832 D 214092 CDS YP_002347220.1 218929345 1175084 complement(2530160..2531662) 1 NC_003143.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 2531662 araA 1175084 araA Yersinia pestis CO92 L-arabinose isomerase YP_002347220.1 2530160 R 214092 CDS YP_002347221.1 218929346 1175085 complement(2531746..2533449) 1 NC_003143.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 2533449 araB 1175085 araB Yersinia pestis CO92 ribulokinase YP_002347221.1 2531746 R 214092 CDS YP_002347222.1 218929347 1175086 2533857..2534840 1 NC_003143.1 L-arabinose-binding protein 2534840 araF 1175086 araF Yersinia pestis CO92 L-arabinose-binding protein YP_002347222.1 2533857 D 214092 CDS YP_002347223.1 218929348 1175087 2534938..2536509 1 NC_003143.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 2536509 araG 1175087 araG Yersinia pestis CO92 L-arabinose transporter ATP-binding protein YP_002347223.1 2534938 D 214092 CDS YP_002347224.1 218929349 1175088 2536527..2537576 1 NC_003143.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 2537576 araH 1175088 araH Yersinia pestis CO92 L-arabinose transporter permease YP_002347224.1 2536527 D 214092 CDS YP_002347225.1 218929350 1175089 2537797..2538729 1 NC_003143.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 2538729 araC 1175089 araC Yersinia pestis CO92 DNA-binding transcriptional regulator AraC YP_002347225.1 2537797 D 214092 CDS YP_002347226.1 218929351 1175090 2538857..2539906 1 NC_003143.1 oxidoreductase 2539906 1175090 YPO2259 Yersinia pestis CO92 oxidoreductase YP_002347226.1 2538857 D 214092 CDS YP_002347227.1 218929352 1175091 2540100..2541128 1 NC_003143.1 hypothetical protein 2541128 1175091 YPO2260 Yersinia pestis CO92 hypothetical protein YP_002347227.1 2540100 D 214092 CDS YP_002347228.1 218929353 1175092 2541334..2541933 1 NC_003143.1 No significant database hits; hypothetical protein 2541933 1175092 YPO2261 Yersinia pestis CO92 hypothetical protein YP_002347228.1 2541334 D 214092 CDS YP_002347229.1 218929354 1175093 complement(2541982..2543526) 1 NC_003143.1 hypothetical protein 2543526 1175093 YPO2262 Yersinia pestis CO92 hypothetical protein YP_002347229.1 2541982 R 214092 CDS YP_002347230.1 218929355 1175094 complement(2543766..2544941) 1 NC_003143.1 mannose-6-phosphate isomerase 2544941 manA 1175094 manA Yersinia pestis CO92 mannose-6-phosphate isomerase YP_002347230.1 2543766 R 214092 CDS YP_008853946.1 559797721 17699570 2545225..2546622 1 NC_003143.1 fumarate hydratase 2546622 17699570 YPO2263a Yersinia pestis CO92 fumarate hydratase YP_008853946.1 2545225 D 214092 CDS YP_002347232.1 218929357 1175096 complement(2546702..2547637) 1 NC_003143.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 2547637 tus 1175096 tus Yersinia pestis CO92 DNA replication terminus site-binding protein YP_002347232.1 2546702 R 214092 CDS YP_002347233.1 218929358 1175097 complement(2548022..2549140) 1 NC_003143.1 hypothetical protein 2549140 1175097 YPO2266 Yersinia pestis CO92 hypothetical protein YP_002347233.1 2548022 R 214092 CDS YP_002347234.1 218929359 1175099 2550453..2551670 1 NC_003143.1 ROK family transcriptional regulator 2551670 mlc 1175099 mlc Yersinia pestis CO92 ROK family transcriptional regulator YP_002347234.1 2550453 D 214092 CDS YP_002347235.1 218929360 1175100 2551894..2552562 1 NC_003143.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 2552562 bioD 1175100 bioD Yersinia pestis CO92 dithiobiotin synthetase YP_002347235.1 2551894 D 214092 CDS YP_002347236.1 218929361 1175101 complement(2552703..2553947) 1 NC_003143.1 voltage-gated ClC-type chloride channel ClcB 2553947 1175101 YPO2270 Yersinia pestis CO92 voltage-gated ClC-type chloride channel ClcB YP_002347236.1 2552703 R 214092 CDS YP_002347237.1 218929362 1175102 complement(2554373..2554636) 1 NC_003143.1 hypothetical protein 2554636 1175102 YPO2271 Yersinia pestis CO92 hypothetical protein YP_002347237.1 2554373 R 214092 CDS YP_002347238.1 218929363 1175103 complement(2554658..2555065) 1 NC_003143.1 hypothetical protein 2555065 1175103 YPO2272 Yersinia pestis CO92 hypothetical protein YP_002347238.1 2554658 R 214092 CDS YP_002347239.1 218929364 1175104 complement(2555162..2555584) 1 NC_003143.1 hypothetical protein 2555584 1175104 YPO2273 Yersinia pestis CO92 hypothetical protein YP_002347239.1 2555162 R 214092 CDS YP_002347240.1 218929365 1175105 2555780..2556832 1 NC_003143.1 hypothetical protein 2556832 1175105 YPO2274 Yersinia pestis CO92 hypothetical protein YP_002347240.1 2555780 D 214092 CDS YP_002347241.1 218929366 1175106 2556844..2557161 1 NC_003143.1 hypothetical protein 2557161 1175106 YPO2275 Yersinia pestis CO92 hypothetical protein YP_002347241.1 2556844 D 214092 CDS YP_002347242.1 218929367 1175107 2557164..2557415 1 NC_003143.1 phage-like membrane protein 2557415 1175107 YPO2276 Yersinia pestis CO92 phage-like membrane protein YP_002347242.1 2557164 D 214092 CDS YP_002347243.1 218929368 1175108 2557412..2557684 1 NC_003143.1 phage-like membrane protein 2557684 1175108 YPO2276a Yersinia pestis CO92 phage-like membrane protein YP_002347243.1 2557412 D 214092 CDS YP_002347244.1 218929369 1175109 2557749..2559461 1 NC_003143.1 hypothetical protein 2559461 1175109 YPO2277 Yersinia pestis CO92 hypothetical protein YP_002347244.1 2557749 D 214092 CDS YP_002347245.1 218929370 1175110 2559474..2559761 1 NC_003143.1 phage-like membrane protein 2559761 1175110 YPO2278 Yersinia pestis CO92 phage-like membrane protein YP_002347245.1 2559474 D 214092 CDS YP_002347246.1 218929371 1175111 2559765..2560790 1 NC_003143.1 phage-like membrane protein 2560790 1175111 YPO2279 Yersinia pestis CO92 phage-like membrane protein YP_002347246.1 2559765 D 214092 CDS YP_002347247.1 218929372 1175112 2560790..2562034 1 NC_003143.1 phage-like secreted protein 2562034 1175112 YPO2280 Yersinia pestis CO92 phage-like secreted protein YP_002347247.1 2560790 D 214092 CDS YP_002347249.1 218929374 1175114 complement(2563093..2563203) 1 NC_003143.1 No significant database hits; hypothetical protein 2563203 1175114 YPO2282 Yersinia pestis CO92 hypothetical protein YP_002347249.1 2563093 R 214092 CDS YP_002347250.1 218929375 1175115 complement(2563325..2564341) 1 NC_003143.1 LacI family transcriptional regulator 2564341 1175115 YPO2283 Yersinia pestis CO92 LacI family transcriptional regulator YP_002347250.1 2563325 R 214092 CDS YP_002347251.1 218929376 1175116 complement(2564405..2564878) 1 NC_003143.1 No significant database hits; hypothetical protein 2564878 1175116 YPO2284 Yersinia pestis CO92 hypothetical protein YP_002347251.1 2564405 R 214092 CDS YP_002347253.1 218929378 1175118 2565808..2566839 1 NC_003143.1 hypothetical protein 2566839 1175118 YPO2286 Yersinia pestis CO92 hypothetical protein YP_002347253.1 2565808 D 214092 CDS YP_002347254.1 218929379 1175119 2566843..2567664 1 NC_003143.1 transport system permease 2567664 1175119 YPO2287 Yersinia pestis CO92 transport system permease YP_002347254.1 2566843 D 214092 CDS YP_002347255.1 218929380 1175120 complement(2567955..2569595) 1 NC_003143.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2569595 amn 1175120 amn Yersinia pestis CO92 AMP nucleosidase YP_002347255.1 2567955 R 214092 CDS YP_002347256.1 218929381 1175121 2569831..2571234 1 NC_003143.1 virulence factor 2571234 1175121 YPO2289 Yersinia pestis CO92 virulence factor YP_002347256.1 2569831 D 214092 CDS YP_002347257.1 218929382 1175122 2571239..2574310 1 NC_003143.1 virulence factor 2574310 1175122 YPO2290 Yersinia pestis CO92 virulence factor YP_002347257.1 2571239 D 214092 CDS YP_002347258.1 218929383 1175123 2574307..2576847 1 NC_003143.1 virulence factor 2576847 1175123 YPO2291 Yersinia pestis CO92 virulence factor YP_002347258.1 2574307 D 214092 CDS YP_002347259.1 218929384 1175124 complement(2577016..2577810) 1 NC_003143.1 lipoprotein 2577810 1175124 YPO2292 Yersinia pestis CO92 lipoprotein YP_002347259.1 2577016 R 214092 CDS YP_002347260.1 218929385 1175125 2578383..2580065 1 NC_003143.1 acetolactate synthase catalytic subunit 2580065 ilvB 1175125 ilvB Yersinia pestis CO92 acetolactate synthase catalytic subunit YP_002347260.1 2578383 D 214092 CDS YP_002347261.1 218929386 1175126 2580067..2580369 1 NC_003143.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 2580369 ilvN 1175126 ilvN Yersinia pestis CO92 acetolactate synthase 1 regulatory subunit YP_002347261.1 2580067 D 214092 CDS YP_002347262.1 218929387 1175127 complement(2580436..2581110) 1 NC_003143.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 2581110 1175127 YPO2295 Yersinia pestis CO92 nucleotidase YP_002347262.1 2580436 R 214092 CDS YP_002347265.1 218929390 1175130 complement(2584182..2585627) 1 NC_003143.1 alkaline phosphatase 2585627 phoA 1175130 phoA Yersinia pestis CO92 alkaline phosphatase YP_002347265.1 2584182 R 214092 CDS YP_002347266.1 218929391 1175131 2585868..2586386 1 NC_003143.1 methylated-DNA--protein-cysteine methyltransferase 2586386 ogt 1175131 ogt Yersinia pestis CO92 methylated-DNA--protein-cysteine methyltransferase YP_002347266.1 2585868 D 214092 CDS YP_002347267.1 218929392 1175132 2586459..2587211 1 NC_003143.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 2587211 fnr 1175132 fnr Yersinia pestis CO92 fumarate/nitrate reduction transcriptional regulator YP_002347267.1 2586459 D 214092 CDS YP_002347268.1 218929393 1175133 2587346..2588302 1 NC_003143.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 2588302 1175133 YPO2301 Yersinia pestis CO92 universal stress protein UspE YP_002347268.1 2587346 D 214092 CDS YP_002347269.1 218929394 1175134 complement(2588577..2589971) 1 NC_003143.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 2589971 pntB 1175134 pntB Yersinia pestis CO92 pyridine nucleotide transhydrogenase YP_002347269.1 2588577 R 214092 CDS YP_002347270.1 218929395 1175135 complement(2590044..2591570) 1 NC_003143.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 2591570 pntA 1175135 pntA Yersinia pestis CO92 NAD(P) transhydrogenase subunit alpha YP_002347270.1 2590044 R 214092 CDS YP_002347271.1 218929396 1175136 complement(2591691..2591894) 1 NC_003143.1 No significant database hits; hypothetical protein 2591894 1175136 YPO2304 Yersinia pestis CO92 hypothetical protein YP_002347271.1 2591691 R 214092 CDS YP_002347272.1 218929397 1175137 2592100..2593053 1 NC_003143.1 hypothetical protein 2593053 1175137 YPO2305 Yersinia pestis CO92 hypothetical protein YP_002347272.1 2592100 D 214092 CDS YP_002347273.1 218929398 1175138 2593323..2594714 1 NC_003143.1 amino acid antiporter 2594714 1175138 YPO2306 Yersinia pestis CO92 amino acid antiporter YP_002347273.1 2593323 D 214092 CDS YP_002347274.1 218929399 1175139 complement(2594738..2595154) 1 NC_003143.1 hypothetical protein 2595154 1175139 YPO2307 Yersinia pestis CO92 hypothetical protein YP_002347274.1 2594738 R 214092 CDS YP_002347275.1 218929400 1175140 2595451..2596197 1 NC_003143.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 2596197 rstA 1175140 rstA Yersinia pestis CO92 DNA-binding transcriptional regulator RstA YP_002347275.1 2595451 D 214092 CDS YP_002347276.1 218929401 1175141 2596225..2597502 1 NC_003143.1 sensor protein RstB 2597502 rstB 1175141 rstB Yersinia pestis CO92 sensor protein RstB YP_002347276.1 2596225 D 214092 CDS YP_002347277.1 218929402 1175142 2597596..2599095 1 NC_003143.1 carboxypeptidase 2599095 1175142 YPO2310 Yersinia pestis CO92 carboxypeptidase YP_002347277.1 2597596 D 214092 CDS YP_002347278.1 218929403 1175143 complement(2599217..2599675) 1 NC_003143.1 transposase for the IS1541 insertion element 2599675 tnp 1175143 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347278.1 2599217 R 214092 CDS YP_002347279.1 218929404 1175144 2600645..2603269 1 NC_003143.1 insecticidal toxin complex 2603269 1175144 YPO2312 Yersinia pestis CO92 insecticidal toxin complex YP_002347279.1 2600645 D 214092 CDS YP_002347280.1 218929405 1175145 2603272..2603628 1 NC_003143.1 No significant database hits; hypothetical protein 2603628 1175145 YPO2313 Yersinia pestis CO92 hypothetical protein YP_002347280.1 2603272 D 214092 CDS YP_002347282.1 218929407 1175147 complement(2604455..2605033) 1 NC_003143.1 hypothetical protein 2605033 1175147 YPO2315 Yersinia pestis CO92 hypothetical protein YP_002347282.1 2604455 R 214092 CDS YP_002347283.1 218929408 1175148 complement(2605059..2605613) 1 NC_003143.1 hypothetical protein 2605613 1175148 YPO2316 Yersinia pestis CO92 hypothetical protein YP_002347283.1 2605059 R 214092 CDS YP_002347284.1 218929409 1175149 2606008..2606220 1 NC_003143.1 No significant database hits. Doubtful CDS; hypothetical protein 2606220 1175149 YPO2317 Yersinia pestis CO92 hypothetical protein YP_002347284.1 2606008 D 214092 CDS YP_002347285.1 218929410 1175150 2606217..2606501 1 NC_003143.1 acid shock protein 2606501 asr 1175150 asr Yersinia pestis CO92 acid shock protein YP_002347285.1 2606217 D 214092 CDS YP_002347286.1 218929411 1175151 2606835..2607671 1 NC_003143.1 pepetidase 2607671 1175151 YPO2319 Yersinia pestis CO92 pepetidase YP_002347286.1 2606835 D 214092 CDS YP_002347287.1 218929412 1175152 complement(2607727..2608050) 1 NC_003143.1 DNA-binding phage-related protein 2608050 1175152 YPO2320 Yersinia pestis CO92 DNA-binding phage-related protein YP_002347287.1 2607727 R 214092 CDS YP_002347288.1 218929413 1175153 complement(2608047..2608361) 1 NC_003143.1 hypothetical protein 2608361 1175153 YPO2321 Yersinia pestis CO92 hypothetical protein YP_002347288.1 2608047 R 214092 CDS YP_002347289.1 218929414 1175154 complement(2608715..2612557) 1 NC_003143.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 2612557 hrpA 1175154 hrpA Yersinia pestis CO92 ATP-dependent RNA helicase HrpA YP_002347289.1 2608715 R 214092 CDS YP_002347290.1 218929415 1175155 2613025..2613630 1 NC_003143.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 2613630 acpD 1175155 acpD Yersinia pestis CO92 azoreductase YP_002347290.1 2613025 D 214092 CDS YP_002347291.1 218929416 1175156 complement(2613751..2614707) 1 NC_003143.1 transcriptional regulator 2614707 1175156 YPO2324 Yersinia pestis CO92 transcriptional regulator YP_002347291.1 2613751 R 214092 CDS YP_002347292.1 218929417 1175157 2614917..2616308 1 NC_003143.1 mannitol dehydrogenase 2616308 dalD 1175157 dalD Yersinia pestis CO92 mannitol dehydrogenase YP_002347292.1 2614917 D 214092 CDS YP_002347293.1 218929418 1175158 complement(2616509..2616880) 1 NC_003143.1 hypothetical protein 2616880 1175158 YPO2326 Yersinia pestis CO92 hypothetical protein YP_002347293.1 2616509 R 214092 CDS YP_002347294.1 218929419 1175159 complement(2616890..2617075) 1 NC_003143.1 lipoprotein 2617075 1175159 YPO2327 Yersinia pestis CO92 lipoprotein YP_002347294.1 2616890 R 214092 CDS YP_002347295.1 218929420 1175160 complement(2617081..2619777) 1 NC_003143.1 hypothetical protein 2619777 1175160 YPO2328 Yersinia pestis CO92 hypothetical protein YP_002347295.1 2617081 R 214092 CDS YP_002347296.1 218929421 1175161 2620043..2621035 1 NC_003143.1 D-lactate dehydrogenase 2621035 hslI 1175161 hslI Yersinia pestis CO92 D-lactate dehydrogenase YP_002347296.1 2620043 D 214092 CDS YP_002347297.1 218929422 1175162 2621105..2621557 1 NC_003143.1 heat-inducible protein 2621557 hslJ 1175162 hslJ Yersinia pestis CO92 heat-inducible protein YP_002347297.1 2621105 D 214092 CDS YP_002347298.1 218929423 1175163 complement(2621615..2621956) 1 NC_003143.1 lipoprotein 2621956 1175163 YPO2331 Yersinia pestis CO92 lipoprotein YP_002347298.1 2621615 R 214092 CDS YP_002347299.1 218929424 1175164 2622241..2622900 1 NC_003143.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase 2622900 1175164 YPO2332 Yersinia pestis CO92 Mg(2+) transport ATPase YP_002347299.1 2622241 D 214092 CDS YP_002347300.1 218929425 1175165 complement(2622960..2623298) 1 NC_003143.1 quaternary ammonium compound-resistance protein 2623298 qacE 1175165 qacE Yersinia pestis CO92 quaternary ammonium compound-resistance protein YP_002347300.1 2622960 R 214092 CDS YP_002347301.1 218929426 1175166 2623771..2627304 1 NC_003143.1 pyruvate-flavodoxin oxidoreductase 2627304 nifJ 1175166 nifJ Yersinia pestis CO92 pyruvate-flavodoxin oxidoreductase YP_002347301.1 2623771 D 214092 CDS YP_002347302.1 218929427 1175167 2627579..2628520 1 NC_003143.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 2628520 1175167 YPO2335 Yersinia pestis CO92 C32 tRNA thiolase YP_002347302.1 2627579 D 214092 CDS YP_002347303.1 218929428 1175168 2628791..2629795 1 NC_003143.1 hypothetical protein 2629795 1175168 YPO2336 Yersinia pestis CO92 hypothetical protein YP_002347303.1 2628791 D 214092 CDS YP_002347304.1 218929429 1175169 2630107..2630946 1 NC_003143.1 regulatory protein 2630946 1175169 YPO2337 Yersinia pestis CO92 regulatory protein YP_002347304.1 2630107 D 214092 CDS YP_002347305.1 218929430 1175170 complement(2631320..2632303) 1 NC_003143.1 zinc transporter 2632303 zntB 1175170 zntB Yersinia pestis CO92 zinc transporter YP_002347305.1 2631320 R 214092 CDS YP_002347306.1 218929431 1175171 complement(2632546..2634162) 1 NC_003143.1 periplasmic murein peptide-binding protein 2634162 mppA 1175171 mppA Yersinia pestis CO92 periplasmic murein peptide-binding protein YP_002347306.1 2632546 R 214092 CDS YP_002347307.1 218929432 1175172 2634540..2635310 1 NC_003143.1 murein peptide amidase A 2635310 1175172 YPO2340 Yersinia pestis CO92 murein peptide amidase A YP_002347307.1 2634540 D 214092 CDS YP_002347308.1 218929433 1175173 complement(2635352..2636326) 1 NC_003143.1 mandelate racemase 2636326 1175173 YPO2341 Yersinia pestis CO92 mandelate racemase YP_002347308.1 2635352 R 214092 CDS YP_002347309.1 218929434 1175174 2636489..2636992 1 NC_003143.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 2636992 tpx 1175174 tpx Yersinia pestis CO92 thiol peroxidase YP_002347309.1 2636489 D 214092 CDS YP_002347310.1 218929435 1175175 2637245..2637703 1 NC_003143.1 transposase for the IS1541 insertion element 2637703 tnp 1175175 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347310.1 2637245 D 214092 CDS YP_002347311.1 218929436 1175176 complement(2637850..2639427) 1 NC_003143.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 2639427 tyrR 1175176 tyrR Yersinia pestis CO92 DNA-binding transcriptional regulator TyrR YP_002347311.1 2637850 R 214092 CDS YP_002347312.1 218929437 1175177 2639762..2640208 1 NC_003143.1 hypothetical protein 2640208 1175177 YPO2345 Yersinia pestis CO92 hypothetical protein YP_002347312.1 2639762 D 214092 CDS YP_002347313.1 218929438 1175178 2640270..2640728 1 NC_003143.1 hypothetical protein 2640728 1175178 YPO2346 Yersinia pestis CO92 hypothetical protein YP_002347313.1 2640270 D 214092 CDS YP_002347314.1 218929439 1175179 complement(2640738..2641799) 1 NC_003143.1 hypothetical protein 2641799 1175179 YPO2347 Yersinia pestis CO92 hypothetical protein YP_002347314.1 2640738 R 214092 CDS YP_002347315.1 218929440 1175180 complement(2641796..2643193) 1 NC_003143.1 hypothetical protein 2643193 1175180 YPO2348 Yersinia pestis CO92 hypothetical protein YP_002347315.1 2641796 R 214092 CDS YP_002347316.1 218929441 1175181 complement(2643501..2643860) 1 NC_003143.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 2643860 pspC 1175181 pspC Yersinia pestis CO92 DNA-binding transcriptional activator PspC YP_002347316.1 2643501 R 214092 CDS YP_002347317.1 218929442 1175182 complement(2643860..2644087) 1 NC_003143.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 2644087 pspB 1175182 pspB Yersinia pestis CO92 phage shock protein B YP_002347317.1 2643860 R 214092 CDS YP_002347318.1 218929443 1175183 complement(2644249..2644914) 1 NC_003143.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 2644914 pspA 1175183 pspA Yersinia pestis CO92 phage shock protein PspA YP_002347318.1 2644249 R 214092 CDS YP_002347319.1 218929444 1175184 2645159..2646187 1 NC_003143.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 2646187 pspF 1175184 pspF Yersinia pestis CO92 phage shock protein operon transcriptional activator YP_002347319.1 2645159 D 214092 CDS YP_002347320.1 218929445 1175185 complement(2646352..2646810) 1 NC_003143.1 transposase for the IS1541 insertion element 2646810 tnp 1175185 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347320.1 2646352 R 214092 CDS YP_002347321.1 218929446 1175186 2647154..2647339 1 NC_003143.1 No significant database hits; hypothetical protein 2647339 1175186 YPO2354 Yersinia pestis CO92 hypothetical protein YP_002347321.1 2647154 D 214092 CDS YP_002347322.1 218929447 1175187 2647475..2649121 1 NC_003143.1 peptide transport periplasmic protein 2649121 sapA 1175187 sapA Yersinia pestis CO92 peptide transport periplasmic protein YP_002347322.1 2647475 D 214092 CDS YP_002347323.1 218929448 1175188 2649118..2650083 1 NC_003143.1 peptide transport system permease 2650083 sapB 1175188 sapB Yersinia pestis CO92 peptide transport system permease YP_002347323.1 2649118 D 214092 CDS YP_002347324.1 218929449 1175189 2650070..2650960 1 NC_003143.1 peptide transport system permease 2650960 sapC 1175189 sapC Yersinia pestis CO92 peptide transport system permease YP_002347324.1 2650070 D 214092 CDS YP_002347325.1 218929450 1175190 2650960..2651952 1 NC_003143.1 peptide transport system ATP-binding protein 2651952 sapD 1175190 sapD Yersinia pestis CO92 peptide transport system ATP-binding protein YP_002347325.1 2650960 D 214092 CDS YP_002347326.1 218929451 1175191 2651952..2652767 1 NC_003143.1 peptide transport system ATP-binding protein 2652767 sapF 1175191 sapF Yersinia pestis CO92 peptide transport system ATP-binding protein YP_002347326.1 2651952 D 214092 CDS YP_002347327.1 218929452 1175192 2653157..2654437 1 NC_003143.1 hypothetical protein 2654437 1175192 YPO2360 Yersinia pestis CO92 hypothetical protein YP_002347327.1 2653157 D 214092 CDS YP_002347328.1 218929453 1175193 2655080..2656585 1 NC_003143.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 2656585 tppB 1175193 tppB Yersinia pestis CO92 tripeptide transporter permease YP_002347328.1 2655080 D 214092 CDS YP_002347329.1 218929454 1175194 2656840..2657430 1 NC_003143.1 hypothetical protein 2657430 1175194 YPO2362 Yersinia pestis CO92 hypothetical protein YP_002347329.1 2656840 D 214092 CDS YP_002347330.1 218929455 1175195 2657676..2657939 1 NC_003143.1 hypothetical protein 2657939 1175195 YPO2363 Yersinia pestis CO92 hypothetical protein YP_002347330.1 2657676 D 214092 CDS YP_002347331.1 218929456 1175196 complement(2658092..2658874) 1 NC_003143.1 transposase/IS protein 2658874 1175196 YPO2364 Yersinia pestis CO92 transposase/IS protein YP_002347331.1 2658092 R 214092 CDS YP_002347332.1 218929457 1175197 complement(2658871..2659893) 1 NC_003143.1 transposase for insertion sequence IS100 2659893 y1093 1175197 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002347332.1 2658871 R 214092 CDS YP_002347333.1 218929458 1175199 2660143..2660748 1 NC_003143.1 glutathionine S-transferase 2660748 gst 1175199 gst Yersinia pestis CO92 glutathionine S-transferase YP_002347333.1 2660143 D 214092 CDS YP_002347334.1 218929459 1175200 complement(2660808..2661668) 1 NC_003143.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 2661668 pdxY 1175200 pdxY Yersinia pestis CO92 pyridoxamine kinase YP_002347334.1 2660808 R 214092 CDS YP_002347335.1 218929460 1175201 complement(2661823..2663097) 1 NC_003143.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2663097 tyrS 1175201 tyrS Yersinia pestis CO92 tyrosyl-tRNA synthetase YP_002347335.1 2661823 R 214092 CDS YP_002347336.1 218929461 1175202 complement(2663279..2663932) 1 NC_003143.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 2663932 pdxH 1175202 pdxH Yersinia pestis CO92 pyridoxamine 5'-phosphate oxidase YP_002347336.1 2663279 R 214092 CDS YP_002347337.1 218929462 1175203 complement(2664023..2664337) 1 NC_003143.1 lipoprotein 2664337 1175203 YPO2371 Yersinia pestis CO92 lipoprotein YP_002347337.1 2664023 R 214092 CDS YP_002347338.1 218929463 1175204 complement(2664395..2665507) 1 NC_003143.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 2665507 anmK 1175204 anmK Yersinia pestis CO92 anhydro-N-acetylmuramic acid kinase YP_002347338.1 2664395 R 214092 CDS YP_002347339.1 218929464 1175205 2666063..2666530 1 NC_003143.1 lipoprotein 2666530 pcp 1175205 pcp Yersinia pestis CO92 lipoprotein YP_002347339.1 2666063 D 214092 CDS YP_002347340.1 218929465 1175206 complement(2666674..2667105) 1 NC_003143.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 2667105 slyA 1175206 slyA Yersinia pestis CO92 transcriptional regulator SlyA YP_002347340.1 2666674 R 214092 CDS YP_002347341.1 218929466 1175207 complement(2667903..2668799) 1 NC_003143.1 aldo/keto reductase 2668799 1175207 YPO2375 Yersinia pestis CO92 aldo/keto reductase YP_002347341.1 2667903 R 214092 CDS YP_002347342.2 559797717 1175208 complement(2668931..2669170) 1 NC_003143.1 hypothetical protein 2669170 1175208 YPO2376 Yersinia pestis CO92 hypothetical protein YP_002347342.2 2668931 R 214092 CDS YP_002347343.1 218929468 1175209 2669344..2670981 1 NC_003143.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein 2670981 1175209 YPO2377 Yersinia pestis CO92 cell division protein YP_002347343.1 2669344 D 214092 CDS YP_002347344.1 218929469 1175210 2671204..2671803 1 NC_003143.1 TetR family transcriptional regulator 2671803 1175210 YPO2378 Yersinia pestis CO92 TetR family transcriptional regulator YP_002347344.1 2671204 D 214092 CDS YP_002347345.1 218929470 1175211 2671891..2672988 1 NC_003143.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 2672988 1175211 YPO2379 Yersinia pestis CO92 N-ethylmaleimide reductase YP_002347345.1 2671891 D 214092 CDS YP_002347346.1 218929471 1175212 complement(2673209..2676163) 1 NC_003143.1 insecticial toxin 2676163 sepC 1175212 sepC Yersinia pestis CO92 insecticial toxin YP_002347346.1 2673209 R 214092 CDS YP_002347347.1 218929472 1175213 2676436..2676843 1 NC_003143.1 lactoylglutathione lyase 2676843 gloA 1175213 gloA Yersinia pestis CO92 lactoylglutathione lyase YP_002347347.1 2676436 D 214092 CDS YP_002347348.1 218929473 1175214 2676955..2677602 1 NC_003143.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 2677602 rnt 1175214 rnt Yersinia pestis CO92 ribonuclease T YP_002347348.1 2676955 D 214092 CDS YP_002347349.1 218929474 1175215 complement(2677911..2678261) 1 NC_003143.1 hypothetical protein 2678261 1175215 YPO2383 Yersinia pestis CO92 hypothetical protein YP_002347349.1 2677911 R 214092 CDS YP_002347350.1 218929475 1175216 complement(2678361..2678582) 1 NC_003143.1 No significant database hits. Doubtful CDS; hypothetical protein 2678582 1175216 YPO2384 Yersinia pestis CO92 hypothetical protein YP_002347350.1 2678361 R 214092 CDS YP_002347351.1 218929476 1175217 2678686..2679552 1 NC_003143.1 hypothetical protein 2679552 1175217 YPO2385 Yersinia pestis CO92 hypothetical protein YP_002347351.1 2678686 D 214092 CDS YP_002347352.1 218929477 1175218 2679930..2680508 1 NC_003143.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 2680508 sodB 1175218 sodB Yersinia pestis CO92 superoxide dismutase YP_002347352.1 2679930 D 214092 CDS YP_002347353.1 218929478 1175219 2681035..2682060 1 NC_003143.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 2682060 purR 1175219 purR Yersinia pestis CO92 DNA-binding transcriptional repressor PurR YP_002347353.1 2681035 D 214092 CDS YP_002347354.1 218929479 1175220 complement(2682149..2683081) 1 NC_003143.1 DNA-binding transcriptional regulator 2683081 1175220 YPO2388 Yersinia pestis CO92 DNA-binding transcriptional regulator YP_002347354.1 2682149 R 214092 CDS YP_002347355.1 218929480 1175221 2683371..2684573 1 NC_003143.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 2684573 1175221 YPO2389 Yersinia pestis CO92 inner membrane transport protein YdhC YP_002347355.1 2683371 D 214092 CDS YP_002347356.1 218929481 1175222 2685053..2686204 1 NC_003143.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane fatty acyl phospholipid synthase 2686204 cfa 1175222 cfa Yersinia pestis CO92 cyclopropane fatty acyl phospholipid synthase YP_002347356.1 2685053 D 214092 CDS YP_002347357.1 218929482 1175223 complement(2686255..2686911) 1 NC_003143.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 2686911 ribE 1175223 ribE Yersinia pestis CO92 riboflavin synthase subunit alpha YP_002347357.1 2686255 R 214092 CDS YP_002347358.1 218929483 1175224 2687160..2688533 1 NC_003143.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 2688533 1175224 YPO2392 Yersinia pestis CO92 multidrug efflux protein YP_002347358.1 2687160 D 214092 CDS YP_002347359.1 218929484 1175227 2689564..2690976 1 NC_003143.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2690976 pykF 1175227 pykF Yersinia pestis CO92 pyruvate kinase YP_002347359.1 2689564 D 214092 CDS YP_002347360.1 218929485 1175228 2691297..2691533 1 NC_003143.1 major outer membrane lipoprotein 2691533 lpp 1175228 lpp Yersinia pestis CO92 major outer membrane lipoprotein YP_002347360.1 2691297 D 214092 CDS YP_002347361.1 218929486 1175229 2691724..2692182 1 NC_003143.1 transposase for the IS1541 insertion element 2692182 tnp 1175229 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347361.1 2691724 D 214092 CDS YP_002347362.1 218929487 1175230 2692764..2693786 1 NC_003143.1 transposase for insertion sequence IS100 2693786 y1093 1175230 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002347362.1 2692764 D 214092 CDS YP_002347363.1 218929488 1175231 2693783..2694565 1 NC_003143.1 transposase/IS protein 2694565 1175231 YPO2397 Yersinia pestis CO92 transposase/IS protein YP_002347363.1 2693783 D 214092 CDS YP_008479716.1 537470179 1175232 complement(2694609..2695628) 1 NC_003143.1 murein L,D-transpeptidase 2695628 1175232 YPO2398 Yersinia pestis CO92 murein L,D-transpeptidase YP_008479716.1 2694609 R 214092 CDS YP_002347364.1 218929489 1175233 complement(2695899..2696321) 1 NC_003143.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 2696321 1175233 YPO2399 Yersinia pestis CO92 cysteine desufuration protein SufE YP_002347364.1 2695899 R 214092 CDS YP_002347365.1 218929490 1175234 complement(2696410..2697630) 1 NC_003143.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 2697630 1175234 YPO2400 Yersinia pestis CO92 bifunctional cysteine desulfurase/selenocysteine lyase YP_002347365.1 2696410 R 214092 CDS YP_002347366.2 284987069 1175235 complement(2697627..2698952) 1 NC_003143.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase 2698952 1175235 YPO2401 Yersinia pestis CO92 cysteine desulfurase YP_002347366.2 2697627 R 214092 CDS YP_002347367.1 218929492 1175236 complement(2698927..2699673) 1 NC_003143.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase 2699673 sufC 1175236 sufC Yersinia pestis CO92 cysteine desulfurase YP_002347367.1 2698927 R 214092 CDS YP_002347368.1 218929493 1175237 complement(2699859..2701370) 1 NC_003143.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase 2701370 1175237 YPO2403 Yersinia pestis CO92 cysteine desulfurase YP_002347368.1 2699859 R 214092 CDS YP_002347369.1 218929494 1175238 complement(2701385..2701756) 1 NC_003143.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 2701756 sufA 1175238 sufA Yersinia pestis CO92 iron-sulfur cluster assembly scaffold protein YP_002347369.1 2701385 R 214092 CDS YP_002347371.1 218929496 1175240 complement(2702351..2702767) 1 NC_003143.1 hypothetical protein 2702767 1175240 YPO2406 Yersinia pestis CO92 hypothetical protein YP_002347371.1 2702351 R 214092 CDS YP_002347372.1 218929497 1175241 complement(2702889..2705945) 1 NC_003143.1 hypothetical protein 2705945 1175241 YPO2407 Yersinia pestis CO92 hypothetical protein YP_002347372.1 2702889 R 214092 CDS YP_002347373.1 218929498 1175242 2706566..2707669 1 NC_003143.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; hypothetical protein 2707669 1175242 YPO2408 Yersinia pestis CO92 hypothetical protein YP_002347373.1 2706566 D 214092 CDS YP_002347374.1 218929499 1175243 complement(2708268..2710652) 1 NC_003143.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 2710652 ppsA 1175243 ppsA Yersinia pestis CO92 phosphoenolpyruvate synthase YP_002347374.1 2708268 R 214092 CDS YP_002347375.1 218929500 1175244 2710989..2711810 1 NC_003143.1 hypothetical protein 2711810 1175244 YPO2410 Yersinia pestis CO92 hypothetical protein YP_002347375.1 2710989 D 214092 CDS YP_002347376.1 218929501 1175245 2711967..2713013 1 NC_003143.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 2713013 aroH 1175245 aroH Yersinia pestis CO92 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002347376.1 2711967 D 214092 CDS YP_002347377.1 218929502 1175247 complement(2714697..2715713) 1 NC_003143.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 2715713 lplA 1175247 lplA Yersinia pestis CO92 lipoate-protein ligase A YP_002347377.1 2714697 R 214092 CDS YP_002347378.1 218929503 1175248 complement(2715838..2716302) 1 NC_003143.1 lipoprotein 2716302 nlpC 1175248 nlpC Yersinia pestis CO92 lipoprotein YP_002347378.1 2715838 R 214092 CDS YP_002347379.1 218929504 1175249 complement(2716582..2716968) 1 NC_003143.1 hypothetical protein 2716968 1175249 YPO2416 Yersinia pestis CO92 hypothetical protein YP_002347379.1 2716582 R 214092 CDS YP_002347380.1 218929505 1175250 complement(2716965..2717309) 1 NC_003143.1 hypothetical protein 2717309 1175250 YPO2417 Yersinia pestis CO92 hypothetical protein YP_002347380.1 2716965 R 214092 CDS YP_002347381.1 218929506 1175251 complement(2717306..2718970) 1 NC_003143.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 2718970 arnT 1175251 arnT Yersinia pestis CO92 4-amino-4-deoxy-L-arabinose transferase YP_002347381.1 2717306 R 214092 CDS YP_002347382.1 218929507 1175252 complement(2718967..2719872) 1 NC_003143.1 hypothetical protein 2719872 1175252 YPO2419 Yersinia pestis CO92 hypothetical protein YP_002347382.1 2718967 R 214092 CDS YP_002347383.1 218929508 1175253 complement(2719869..2721872) 1 NC_003143.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 2721872 1175253 YPO2420 Yersinia pestis CO92 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_002347383.1 2719869 R 214092 CDS YP_002347384.1 218929509 1175254 complement(2721869..2722852) 1 NC_003143.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 2722852 pmrF 1175254 pmrF Yersinia pestis CO92 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_002347384.1 2721869 R 214092 CDS YP_002347385.1 218929510 1175255 complement(2722839..2723993) 1 NC_003143.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 2723993 1175255 YPO2422 Yersinia pestis CO92 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_002347385.1 2722839 R 214092 CDS YP_002347386.1 218929511 1175256 complement(2724343..2725104) 1 NC_003143.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 2725104 btuD 1175256 btuD Yersinia pestis CO92 vitamin B12-transporter ATPase YP_002347386.1 2724343 R 214092 CDS YP_002347387.1 218929512 1175257 complement(2725126..2725680) 1 NC_003143.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane; glutathione peroxidase 2725680 btuE 1175257 btuE Yersinia pestis CO92 glutathione peroxidase YP_002347387.1 2725126 R 214092 CDS YP_002347388.1 218929513 1175258 complement(2725750..2726757) 1 NC_003143.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 2726757 btuC 1175258 btuC Yersinia pestis CO92 vtamin B12-transporter permease YP_002347388.1 2725750 R 214092 CDS YP_002347389.1 218929514 1175259 complement(2726984..2727442) 1 NC_003143.1 hypothetical protein 2727442 1175259 YPO2426 Yersinia pestis CO92 hypothetical protein YP_002347389.1 2726984 R 214092 CDS YP_002347390.1 218929515 1175260 complement(2727776..2728072) 1 NC_003143.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 2728072 ihfA 1175260 ihfA Yersinia pestis CO92 integration host factor subunit alpha YP_002347390.1 2727776 R 214092 CDS YP_002347391.1 218929516 1175261 complement(2728077..2730464) 1 NC_003143.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2730464 pheT 1175261 pheT Yersinia pestis CO92 phenylalanyl-tRNA synthetase subunit beta YP_002347391.1 2728077 R 214092 CDS YP_002347392.1 218929517 1175262 complement(2730478..2731461) 1 NC_003143.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2731461 pheS 1175262 pheS Yersinia pestis CO92 phenylalanyl-tRNA synthetase subunit alpha YP_002347392.1 2730478 R 214092 CDS YP_002347394.1 218929519 1175264 complement(2731960..2732316) 1 NC_003143.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2732316 rplT 1175264 rplT Yersinia pestis CO92 50S ribosomal protein L20 YP_002347394.1 2731960 R 214092 CDS YP_002347395.1 218929520 1175265 complement(2732354..2732551) 1 NC_003143.1 50S ribosomal protein L35 2732551 rpmI 1175265 rpmI Yersinia pestis CO92 50S ribosomal protein L35 YP_002347395.1 2732354 R 214092 CDS YP_002347396.1 218929521 1175266 complement(2732648..2733199) 1 NC_003143.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2733199 infC 1175266 infC Yersinia pestis CO92 translation initiation factor IF-3 YP_002347396.1 2732648 R 214092 CDS YP_002347397.1 218929522 1175267 complement(2733203..2735131) 1 NC_003143.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 2735131 thrS 1175267 thrS Yersinia pestis CO92 threonyl-tRNA synthetase YP_002347397.1 2733203 R 214092 CDS YP_002347398.1 218929523 1175268 2735522..2735734 1 NC_003143.1 hypothetical protein 2735734 1175268 YPO2434 Yersinia pestis CO92 hypothetical protein YP_002347398.1 2735522 D 214092 CDS YP_002347400.1 218929525 1175270 complement(2736493..2736807) 1 NC_003143.1 No significant database hits; hypothetical protein 2736807 1175270 YPO2436 Yersinia pestis CO92 hypothetical protein YP_002347400.1 2736493 R 214092 CDS YP_002347401.1 218929526 1175271 2737063..2737746 1 NC_003143.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 2737746 marC 1175271 marC Yersinia pestis CO92 multiple drug resistance protein MarC YP_002347401.1 2737063 D 214092 CDS YP_002347402.1 218929527 1175272 complement(2737868..2738530) 1 NC_003143.1 membrane-bound lytic murein transglycosylase 2738530 1175272 YPO2438 Yersinia pestis CO92 membrane-bound lytic murein transglycosylase YP_002347402.1 2737868 R 214092 CDS YP_002347403.1 218929528 1175273 2738739..2739710 1 NC_003143.1 substrate-binding protein 2739710 yfeA 1175273 yfeA Yersinia pestis CO92 substrate-binding protein YP_002347403.1 2738739 D 214092 CDS YP_002347404.1 218929529 1175274 2739707..2740597 1 NC_003143.1 ATP-binding transport protein 2740597 yfeB 1175274 yfeB Yersinia pestis CO92 ATP-binding transport protein YP_002347404.1 2739707 D 214092 CDS YP_002347405.1 218929530 1175275 2740597..2741481 1 NC_003143.1 chelated iron transport system membrane protein 2741481 yfeC 1175275 yfeC Yersinia pestis CO92 chelated iron transport system membrane protein YP_002347405.1 2740597 D 214092 CDS YP_002347406.1 218929531 1175276 2741478..2742371 1 NC_003143.1 chelated iron transport system membrane protein 2742371 yfeD 1175276 yfeD Yersinia pestis CO92 chelated iron transport system membrane protein YP_002347406.1 2741478 D 214092 CDS YP_002347408.1 218929533 1175278 2742676..2743551 1 NC_003143.1 hypothetical protein 2743551 1175278 YPO2444 Yersinia pestis CO92 hypothetical protein YP_002347408.1 2742676 D 214092 CDS YP_002347409.1 218929534 1175279 complement(2743680..2744234) 1 NC_003143.1 yfeABCD locus regulator 2744234 yfeE 1175279 yfeE Yersinia pestis CO92 yfeABCD locus regulator YP_002347409.1 2743680 R 214092 CDS YP_002347410.1 218929535 1175280 2744645..2745310 1 NC_003143.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 2745310 1175280 YPO2446 Yersinia pestis CO92 2-deoxyglucose-6-phosphatase YP_002347410.1 2744645 D 214092 CDS YP_002347411.1 218929536 1175281 complement(2745561..2746769) 1 NC_003143.1 transposase for the IS285 insertion element 2746769 y1062 1175281 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002347411.1 2745561 R 214092 CDS YP_002347412.1 218929537 1175282 2747130..2748245 1 NC_003143.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 2748245 solA 1175282 solA Yersinia pestis CO92 N-methyltryptophan oxidase YP_002347412.1 2747130 D 214092 CDS YP_002347413.1 218929538 1175283 2748512..2749126 1 NC_003143.1 LuxR family transcriptional regulator 2749126 1175283 YPO2449 Yersinia pestis CO92 LuxR family transcriptional regulator YP_002347413.1 2748512 D 214092 CDS YP_002347414.1 218929539 1175284 complement(2749698..2750756) 1 NC_003143.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes; transport protein 2750756 tqsA 1175284 tqsA Yersinia pestis CO92 transport protein YP_002347414.1 2749698 R 214092 CDS YP_002347415.1 218929540 1175285 complement(2750905..2751972) 1 NC_003143.1 hypothetical protein 2751972 1175285 YPO2451 Yersinia pestis CO92 hypothetical protein YP_002347415.1 2750905 R 214092 CDS YP_002347416.1 218929541 1175286 complement(2752016..2752144) 1 NC_003143.1 No significant database hits. Doubtful CDS; hypothetical protein 2752144 1175286 YPO2452 Yersinia pestis CO92 hypothetical protein YP_002347416.1 2752016 R 214092 CDS YP_002347419.1 218929544 1175289 complement(2753023..2753721) 1 NC_003143.1 hypothetical protein 2753721 1175289 YPO2455 Yersinia pestis CO92 hypothetical protein YP_002347419.1 2753023 R 214092 CDS YP_002347420.1 218929545 1175290 2754119..2754775 1 NC_003143.1 N-acylhomoserine lactone synthase 2754775 ypeI 1175290 ypeI Yersinia pestis CO92 N-acylhomoserine lactone synthase YP_002347420.1 2754119 D 214092 CDS YP_002347421.1 218929546 1175291 complement(2754768..2755505) 1 NC_003143.1 quorum-sensing transcriptional activator YpeR 2755505 ypeR 1175291 ypeR Yersinia pestis CO92 quorum-sensing transcriptional activator YpeR YP_002347421.1 2754768 R 214092 CDS YP_002347422.1 218929547 1175292 complement(2755992..2756972) 1 NC_003143.1 LysR family transcriptional regulator 2756972 1175292 YPO2458 Yersinia pestis CO92 LysR family transcriptional regulator YP_002347422.1 2755992 R 214092 CDS YP_002347423.1 218929548 1175293 2757366..2758724 1 NC_003143.1 transporter protein 2758724 1175293 YPO2459 Yersinia pestis CO92 transporter protein YP_002347423.1 2757366 D 214092 CDS YP_002347424.1 218929549 1175294 2758771..2759274 1 NC_003143.1 hypothetical protein 2759274 1175294 YPO2460 Yersinia pestis CO92 hypothetical protein YP_002347424.1 2758771 D 214092 CDS YP_002347425.1 218929550 1175295 2759285..2760304 1 NC_003143.1 oxidoreductase 2760304 1175295 YPO2461 Yersinia pestis CO92 oxidoreductase YP_002347425.1 2759285 D 214092 CDS YP_002347426.1 218929551 1175296 complement(2760382..2760936) 1 NC_003143.1 hypothetical protein 2760936 1175296 YPO2462 Yersinia pestis CO92 hypothetical protein YP_002347426.1 2760382 R 214092 CDS YP_002347427.1 218929552 1175297 complement(2760947..2761951) 1 NC_003143.1 hypothetical protein 2761951 1175297 YPO2463 Yersinia pestis CO92 hypothetical protein YP_002347427.1 2760947 R 214092 CDS YP_002347428.1 218929553 1175298 complement(2761969..2762919) 1 NC_003143.1 hypothetical protein 2762919 1175298 YPO2464 Yersinia pestis CO92 hypothetical protein YP_002347428.1 2761969 R 214092 CDS YP_002347429.1 218929554 1175299 complement(2762916..2764262) 1 NC_003143.1 hypothetical protein 2764262 1175299 YPO2465 Yersinia pestis CO92 hypothetical protein YP_002347429.1 2762916 R 214092 CDS YP_002347431.1 218929556 1175301 complement(2764670..2767957) 1 NC_003143.1 hypothetical protein 2767957 1175301 YPO2467 Yersinia pestis CO92 hypothetical protein YP_002347431.1 2764670 R 214092 CDS YP_002347432.1 218929557 1175302 complement(2767954..2768940) 1 NC_003143.1 hypothetical protein 2768940 1175302 YPO2468 Yersinia pestis CO92 hypothetical protein YP_002347432.1 2767954 R 214092 CDS YP_002347433.1 218929558 1175303 complement(2769322..2769654) 1 NC_003143.1 hypothetical protein 2769654 1175303 YPO2469 Yersinia pestis CO92 hypothetical protein YP_002347433.1 2769322 R 214092 CDS YP_002347434.1 218929559 1175304 2770137..2771384 1 NC_003143.1 hypothetical protein 2771384 1175304 YPO2470 Yersinia pestis CO92 hypothetical protein YP_002347434.1 2770137 D 214092 CDS YP_002347435.1 218929560 1175305 complement(2771967..2773241) 1 NC_003143.1 hypothetical protein 2773241 1175305 YPO2471 Yersinia pestis CO92 hypothetical protein YP_002347435.1 2771967 R 214092 CDS YP_002347436.1 218929561 1175306 complement(2773280..2774395) 1 NC_003143.1 hypothetical protein 2774395 1175306 YPO2472 Yersinia pestis CO92 hypothetical protein YP_002347436.1 2773280 R 214092 CDS YP_002347437.1 218929562 1175307 complement(2774518..2775456) 1 NC_003143.1 No significant database hits; hypothetical protein 2775456 1175307 YPO2473 Yersinia pestis CO92 hypothetical protein YP_002347437.1 2774518 R 214092 CDS YP_002347438.1 218929563 1175308 complement(2775483..2776538) 1 NC_003143.1 hypothetical protein 2776538 1175308 YPO2474 Yersinia pestis CO92 hypothetical protein YP_002347438.1 2775483 R 214092 CDS YP_002347439.1 218929564 1175309 complement(2776685..2777509) 1 NC_003143.1 sugar ABC transporter permease 2777509 1175309 YPO2475 Yersinia pestis CO92 sugar ABC transporter permease YP_002347439.1 2776685 R 214092 CDS YP_002347440.1 218929565 1175310 complement(2777510..2778385) 1 NC_003143.1 sugar ABC transporter permease 2778385 1175310 YPO2476 Yersinia pestis CO92 sugar ABC transporter permease YP_002347440.1 2777510 R 214092 CDS YP_002347441.1 218929566 1175311 complement(2778494..2779780) 1 NC_003143.1 solute-binding protein 2779780 1175311 YPO2477 Yersinia pestis CO92 solute-binding protein YP_002347441.1 2778494 R 214092 CDS YP_002347442.1 218929567 1175312 2780052..2781092 1 NC_003143.1 LacI family transcriptional regulator 2781092 1175312 YPO2478 Yersinia pestis CO92 LacI family transcriptional regulator YP_002347442.1 2780052 D 214092 CDS YP_002347443.1 218929568 1175313 2781109..2782497 1 NC_003143.1 phosphomannomutase 2782497 manB 1175313 manB Yersinia pestis CO92 phosphomannomutase YP_002347443.1 2781109 D 214092 CDS YP_002347444.1 218929569 1175314 2782597..2783676 1 NC_003143.1 mannitol transport ATP-binding protein 2783676 mtlK 1175314 mtlK Yersinia pestis CO92 mannitol transport ATP-binding protein YP_002347444.1 2782597 D 214092 CDS YP_002347445.1 218929570 1175315 complement(2783941..2784486) 1 NC_003143.1 hypothetical protein 2784486 1175315 YPO2481 Yersinia pestis CO92 hypothetical protein YP_002347445.1 2783941 R 214092 CDS YP_002347446.1 218929571 1175316 complement(2784744..2785196) 1 NC_003143.1 hypothetical protein 2785196 1175316 YPO2482 Yersinia pestis CO92 hypothetical protein YP_002347446.1 2784744 R 214092 CDS YP_002347447.1 218929572 1175317 complement(2785296..2785700) 1 NC_003143.1 hypothetical protein 2785700 1175317 YPO2483 Yersinia pestis CO92 hypothetical protein YP_002347447.1 2785296 R 214092 CDS YP_002347448.1 218929573 1175318 complement(2785842..2786009) 1 NC_003143.1 No significant database hits; hypothetical protein 2786009 1175318 YPO2484 Yersinia pestis CO92 hypothetical protein YP_002347448.1 2785842 R 214092 CDS YP_002347449.1 218929574 1175319 complement(2786212..2786409) 1 NC_003143.1 hypothetical protein 2786409 1175319 YPO2485 Yersinia pestis CO92 hypothetical protein YP_002347449.1 2786212 R 214092 CDS YP_002347450.1 218929575 1175320 complement(2786419..2788452) 1 NC_003143.1 hypothetical protein 2788452 1175320 YPO2486 Yersinia pestis CO92 hypothetical protein YP_002347450.1 2786419 R 214092 CDS YP_002347452.1 218929577 1175322 complement(2789116..2789367) 1 NC_003143.1 hypothetical protein 2789367 1175322 YPO2488 Yersinia pestis CO92 hypothetical protein YP_002347452.1 2789116 R 214092 CDS YP_002347453.1 218929578 1175323 complement(2789612..2790115) 1 NC_003143.1 hypothetical protein 2790115 1175323 YPO2489 Yersinia pestis CO92 hypothetical protein YP_002347453.1 2789612 R 214092 CDS YP_002347454.1 218929579 1175324 complement(2790123..2797730) 1 NC_003143.1 hemolysin 2797730 1175324 YPO2490 Yersinia pestis CO92 hemolysin YP_002347454.1 2790123 R 214092 CDS YP_002347455.1 218929580 1175325 complement(2797874..2799562) 1 NC_003143.1 hemolysin activator protein 2799562 1175325 YPO2491 Yersinia pestis CO92 hemolysin activator protein YP_002347455.1 2797874 R 214092 CDS YP_002347456.1 218929581 1175326 complement(2800214..2801179) 1 NC_003143.1 dioxygenase subunit beta 2801179 1175326 YPO2492 Yersinia pestis CO92 dioxygenase subunit beta YP_002347456.1 2800214 R 214092 CDS YP_002347457.1 218929582 1175327 complement(2801275..2802399) 1 NC_003143.1 dioxygenase subunit alpha 2802399 1175327 YPO2493 Yersinia pestis CO92 dioxygenase subunit alpha YP_002347457.1 2801275 R 214092 CDS YP_002347458.1 218929583 1175328 complement(2802516..2803997) 1 NC_003143.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function; transporter 2803997 1175328 YPO2494 Yersinia pestis CO92 transporter YP_002347458.1 2802516 R 214092 CDS YP_002347459.1 218929584 1175329 complement(2804528..2804710) 1 NC_003143.1 hypothetical protein 2804710 1175329 YPO2495 Yersinia pestis CO92 hypothetical protein YP_002347459.1 2804528 R 214092 CDS YP_002347460.1 218929585 1175330 complement(2804779..2805876) 1 NC_003143.1 tartrate dehydrogenase 2805876 1175330 YPO2496 Yersinia pestis CO92 tartrate dehydrogenase YP_002347460.1 2804779 R 214092 CDS YP_002347461.1 218929586 1175331 2805967..2806908 1 NC_003143.1 LysR family transcriptional regulator 2806908 1175331 YPO2497 Yersinia pestis CO92 LysR family transcriptional regulator YP_002347461.1 2805967 D 214092 CDS YP_002347462.1 218929587 1175332 2807155..2808159 1 NC_003143.1 LacI family transcriptional regulator 2808159 1175332 YPO2498 Yersinia pestis CO92 LacI family transcriptional regulator YP_002347462.1 2807155 D 214092 CDS YP_002347463.1 218929588 1175333 complement(2808292..2809284) 1 NC_003143.1 sugar transport system permease 2809284 rbsC 1175333 rbsC Yersinia pestis CO92 sugar transport system permease YP_002347463.1 2808292 R 214092 CDS YP_002347464.1 218929589 1175334 complement(2809281..2810771) 1 NC_003143.1 sugar transport system ATP-binding protein 2810771 rbsA 1175334 rbsA Yersinia pestis CO92 sugar transport system ATP-binding protein YP_002347464.1 2809281 R 214092 CDS YP_002347465.1 218929590 1175335 complement(2810811..2811728) 1 NC_003143.1 sugar binding protein 2811728 rbsB 1175335 rbsB Yersinia pestis CO92 sugar binding protein YP_002347465.1 2810811 R 214092 CDS YP_002347466.1 218929591 1175336 complement(2811903..2813129) 1 NC_003143.1 zinc-binding dehydrogenase 2813129 gutB 1175336 gutB Yersinia pestis CO92 zinc-binding dehydrogenase YP_002347466.1 2811903 R 214092 CDS YP_002347467.1 218929592 1175337 complement(2813712..2814380) 1 NC_003143.1 hypothetical protein 2814380 1175337 YPO2503 Yersinia pestis CO92 hypothetical protein YP_002347467.1 2813712 R 214092 CDS YP_002347468.1 218929593 1175338 complement(2814576..2815118) 1 NC_003143.1 No significant database hits. CDS DNA has a low G+C content, 38.85%.; hypothetical protein 2815118 1175338 YPO2504 Yersinia pestis CO92 hypothetical protein YP_002347468.1 2814576 R 214092 CDS YP_002347469.1 218929594 1175339 complement(2815356..2816294) 1 NC_003143.1 hypothetical protein 2816294 1175339 YPO2505 Yersinia pestis CO92 hypothetical protein YP_002347469.1 2815356 R 214092 CDS YP_002347470.1 218929595 1175340 complement(2816610..2817134) 1 NC_003143.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 2817134 ompX 1175340 ompX Yersinia pestis CO92 outer membrane protein X YP_002347470.1 2816610 R 214092 CDS YP_002347471.1 218929596 1175341 2817539..2818426 1 NC_003143.1 threonine and homoserine efflux system 2818426 1175341 YPO2507 Yersinia pestis CO92 threonine and homoserine efflux system YP_002347471.1 2817539 D 214092 CDS YP_002347472.1 218929597 1175342 2818442..2818939 1 NC_003143.1 hypothetical protein 2818939 1175342 YPO2508 Yersinia pestis CO92 hypothetical protein YP_002347472.1 2818442 D 214092 CDS YP_002347473.1 218929598 1175343 2818962..2819738 1 NC_003143.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 2819738 tam 1175343 tam Yersinia pestis CO92 trans-aconitate 2-methyltransferase YP_002347473.1 2818962 D 214092 CDS YP_002347474.1 218929599 1175344 2819995..2820498 1 NC_003143.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 2820498 dps 1175344 dps Yersinia pestis CO92 DNA starvation/stationary phase protection protein Dps YP_002347474.1 2819995 D 214092 CDS YP_002347475.1 218929600 1175345 2820818..2821945 1 NC_003143.1 hypothetical protein 2821945 1175345 YPO2511 Yersinia pestis CO92 hypothetical protein YP_002347475.1 2820818 D 214092 CDS YP_002347476.1 218929601 1175346 2822515..2823258 1 NC_003143.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter substrate-binding protein 2823258 glnH 1175346 glnH Yersinia pestis CO92 glutamine ABC transporter substrate-binding protein YP_002347476.1 2822515 D 214092 CDS YP_002347477.1 218929602 1175347 2823293..2823949 1 NC_003143.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 2823949 glnP 1175347 glnP Yersinia pestis CO92 glutamine ABC transporter permease YP_002347477.1 2823293 D 214092 CDS YP_002347478.1 218929603 1175348 2823946..2824668 1 NC_003143.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 2824668 glnQ 1175348 glnQ Yersinia pestis CO92 glutamine ABC transporter ATP-binding protein YP_002347478.1 2823946 D 214092 CDS YP_002347479.1 218929604 1175349 complement(2824908..2826155) 1 NC_003143.1 chemotactic transducer 2826155 1175349 YPO2515 Yersinia pestis CO92 chemotactic transducer YP_002347479.1 2824908 R 214092 CDS YP_002347480.1 218929605 1175350 2826265..2827287 1 NC_003143.1 transposase for insertion sequence IS100 2827287 y1093 1175350 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002347480.1 2826265 D 214092 CDS YP_002347481.1 218929606 1175351 2827284..2828066 1 NC_003143.1 transposase/IS protein 2828066 1175351 YPO2517 Yersinia pestis CO92 transposase/IS protein YP_002347481.1 2827284 D 214092 CDS YP_002347482.1 218929607 1175352 complement(2828928..2829938) 1 NC_003143.1 SAM-dependent methyltransferase 2829938 1175352 YPO2519 Yersinia pestis CO92 SAM-dependent methyltransferase YP_002347482.1 2828928 R 214092 CDS YP_002347483.1 218929608 1175353 2830226..2830486 1 NC_003143.1 hypothetical protein 2830486 1175353 YPO2521 Yersinia pestis CO92 hypothetical protein YP_002347483.1 2830226 D 214092 CDS YP_008479717.1 537470180 16744765 complement(2830477..2830635) 1 NC_003143.1 hypothetical protein 2830635 16744765 YPO2521a Yersinia pestis CO92 hypothetical protein YP_008479717.1 2830477 R 214092 CDS YP_002347484.1 218929609 1175354 complement(2830868..2831827) 1 NC_003143.1 glycosyl transferase family protein 2831827 ybiB 1175354 ybiB Yersinia pestis CO92 glycosyl transferase family protein YP_002347484.1 2830868 R 214092 CDS YP_002347485.1 218929610 1175355 complement(2831893..2833308) 1 NC_003143.1 O-succinylbenzoic acid--CoA ligase 2833308 menE 1175355 menE Yersinia pestis CO92 O-succinylbenzoic acid--CoA ligase YP_002347485.1 2831893 R 214092 CDS YP_002347486.1 218929611 1175356 complement(2833296..2834267) 1 NC_003143.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 2834267 menC 1175356 menC Yersinia pestis CO92 O-succinylbenzoate synthase YP_002347486.1 2833296 R 214092 CDS YP_002347487.1 218929612 1175357 complement(2834267..2835124) 1 NC_003143.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 2835124 menB 1175357 menB Yersinia pestis CO92 naphthoate synthase YP_002347487.1 2834267 R 214092 CDS YP_002347488.1 218929613 1175358 complement(2835138..2835956) 1 NC_003143.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase 2835956 1175358 YPO2526 Yersinia pestis CO92 acyl-CoA thioester hydrolase YP_002347488.1 2835138 R 214092 CDS YP_002347489.1 218929614 1175359 complement(2835953..2837656) 1 NC_003143.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 2837656 menD 1175359 menD Yersinia pestis CO92 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_002347489.1 2835953 R 214092 CDS YP_002347490.1 218929615 1175360 complement(2837884..2839251) 1 NC_003143.1 menaquinone-specific isochorismate synthase 2839251 menF 1175360 menF Yersinia pestis CO92 menaquinone-specific isochorismate synthase YP_002347490.1 2837884 R 214092 CDS YP_002347491.1 218929616 1175361 complement(2839779..2840423) 1 NC_003143.1 hypothetical protein 2840423 1175361 YPO2530 Yersinia pestis CO92 hypothetical protein YP_002347491.1 2839779 R 214092 CDS YP_002347492.1 218929617 1175362 complement(2840978..2841286) 1 NC_003143.1 hypothetical protein 2841286 elaB 1175362 elaB Yersinia pestis CO92 hypothetical protein YP_002347492.1 2840978 R 214092 CDS YP_008479718.1 537470181 16744766 2841811..2841993 1 NC_003143.1 membrane protein 2841993 16744766 YPO2531a Yersinia pestis CO92 membrane protein YP_008479718.1 2841811 D 214092 CDS YP_002347494.1 218929619 1175364 complement(2842212..2844089) 1 NC_003143.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 2844089 edd 1175364 edd Yersinia pestis CO92 phosphogluconate dehydratase YP_002347494.1 2842212 R 214092 CDS YP_002347495.1 218929620 1175365 complement(2844093..2844608) 1 NC_003143.1 hypothetical protein 2844608 1175365 YPO2534 Yersinia pestis CO92 hypothetical protein YP_002347495.1 2844093 R 214092 CDS YP_002347496.1 218929621 1175366 complement(2844638..2845969) 1 NC_003143.1 sugar transporter 2845969 1175366 YPO2535 Yersinia pestis CO92 sugar transporter YP_002347496.1 2844638 R 214092 CDS YP_002347497.1 218929622 1175367 complement(2846500..2847450) 1 NC_003143.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein 2847450 1175367 YPO2536 Yersinia pestis CO92 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_002347497.1 2846500 R 214092 CDS YP_002347498.1 218929623 1175368 complement(2847916..2848908) 1 NC_003143.1 LacI family transcriptional regulator 2848908 1175368 YPO2537 Yersinia pestis CO92 LacI family transcriptional regulator YP_002347498.1 2847916 R 214092 CDS YP_002347499.1 218929624 1175369 2849377..2850660 1 NC_003143.1 lipoprotein 2850660 1175369 YPO2538 Yersinia pestis CO92 lipoprotein YP_002347499.1 2849377 D 214092 CDS YP_002347500.1 218929625 1175370 2851419..2852183 1 NC_003143.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase 2852183 idnO 1175370 idnO Yersinia pestis CO92 gluconate 5-dehydrogenase YP_002347500.1 2851419 D 214092 CDS YP_002347501.1 218929626 1175371 2852232..2852768 1 NC_003143.1 thermosensitive gluconokinase 2852768 gntV 1175371 gntV Yersinia pestis CO92 thermosensitive gluconokinase YP_002347501.1 2852232 D 214092 CDS YP_002347502.1 218929627 1175372 2852846..2853313 1 NC_003143.1 hypothetical protein 2853313 1175372 YPO2541 Yersinia pestis CO92 hypothetical protein YP_002347502.1 2852846 D 214092 CDS YP_002347503.1 218929628 1175373 complement(2853651..2854841) 1 NC_003143.1 hypothetical protein 2854841 1175373 YPO2542 Yersinia pestis CO92 hypothetical protein YP_002347503.1 2853651 R 214092 CDS YP_002347504.1 218929629 1175374 complement(2855077..2856540) 1 NC_003143.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 2856540 nuoN 1175374 nuoN Yersinia pestis CO92 NADH dehydrogenase subunit N YP_002347504.1 2855077 R 214092 CDS YP_002347505.1 218929630 1175375 complement(2856547..2858079) 1 NC_003143.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 2858079 nuoM 1175375 nuoM Yersinia pestis CO92 NADH dehydrogenase subunit M YP_002347505.1 2856547 R 214092 CDS YP_002347506.1 218929631 1175376 complement(2858119..2859963) 1 NC_003143.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 2859963 nuoL 1175376 nuoL Yersinia pestis CO92 NADH dehydrogenase subunit L YP_002347506.1 2858119 R 214092 CDS YP_002347507.1 218929632 1175377 complement(2859960..2860262) 1 NC_003143.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 2860262 nuoK 1175377 nuoK Yersinia pestis CO92 NADH dehydrogenase subunit K YP_002347507.1 2859960 R 214092 CDS YP_002347508.1 218929633 1175378 complement(2860259..2860804) 1 NC_003143.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 2860804 nuoJ 1175378 nuoJ Yersinia pestis CO92 NADH dehydrogenase subunit J YP_002347508.1 2860259 R 214092 CDS YP_002347509.1 218929634 1175379 complement(2860817..2861359) 1 NC_003143.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 2861359 nuoI 1175379 nuoI Yersinia pestis CO92 NADH dehydrogenase subunit I YP_002347509.1 2860817 R 214092 CDS YP_002347510.1 218929635 1175380 complement(2861374..2862351) 1 NC_003143.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 2862351 nuoH 1175380 nuoH Yersinia pestis CO92 NADH dehydrogenase subunit H YP_002347510.1 2861374 R 214092 CDS YP_002347511.1 218929636 1175381 complement(2862348..2865092) 1 NC_003143.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 2865092 nuoG 1175381 nuoG Yersinia pestis CO92 NADH dehydrogenase subunit G YP_002347511.1 2862348 R 214092 CDS YP_002347512.1 218929637 1175382 complement(2865179..2866564) 1 NC_003143.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 2866564 nuoF 1175382 nuoF Yersinia pestis CO92 NADH dehydrogenase I subunit F YP_002347512.1 2865179 R 214092 CDS YP_002347513.1 218929638 1175383 complement(2866561..2867079) 1 NC_003143.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 2867079 nuoE 1175383 nuoE Yersinia pestis CO92 NADH dehydrogenase subunit E YP_002347513.1 2866561 R 214092 CDS YP_002347514.1 218929639 1175384 complement(2867127..2868923) 1 NC_003143.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 2868923 nuoD 1175384 nuoD Yersinia pestis CO92 bifunctional NADH:ubiquinone oxidoreductase subunit C/D YP_002347514.1 2867127 R 214092 CDS YP_002347515.1 218929640 1175385 complement(2869064..2869741) 1 NC_003143.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 2869741 nuoB 1175385 nuoB Yersinia pestis CO92 NADH dehydrogenase subunit B YP_002347515.1 2869064 R 214092 CDS YP_002347516.1 218929641 1175386 complement(2869843..2870337) 1 NC_003143.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 2870337 nuoA 1175386 nuoA Yersinia pestis CO92 NADH dehydrogenase subunit A YP_002347516.1 2869843 R 214092 CDS YP_002347517.1 218929642 1175387 complement(2871021..2871953) 1 NC_003143.1 LysR family transcriptional regulator 2871953 hexA 1175387 hexA Yersinia pestis CO92 LysR family transcriptional regulator YP_002347517.1 2871021 R 214092 CDS YP_002347519.1 218929644 1175389 2872809..2874023 1 NC_003143.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase 2874023 aat 1175389 aat Yersinia pestis CO92 aminotransferase YP_002347519.1 2872809 D 214092 CDS YP_002347520.1 218929645 1175390 2874174..2874767 1 NC_003143.1 hypothetical protein 2874767 1175390 YPO2559 Yersinia pestis CO92 hypothetical protein YP_002347520.1 2874174 D 214092 CDS YP_002347521.1 218929646 1175391 complement(2874814..2875083) 1 NC_003143.1 hypothetical protein 2875083 1175391 YPO2560 Yersinia pestis CO92 hypothetical protein YP_002347521.1 2874814 R 214092 CDS YP_002347522.1 218929647 1175392 complement(2875110..2876942) 1 NC_003143.1 ion transport protein 2876942 1175392 YPO2561 Yersinia pestis CO92 ion transport protein YP_002347522.1 2875110 R 214092 CDS YP_002347523.1 218929648 1175393 complement(2877234..2877890) 1 NC_003143.1 phosphatase 2877890 1175393 YPO2562 Yersinia pestis CO92 phosphatase YP_002347523.1 2877234 R 214092 CDS YP_002347524.1 218929649 1175394 complement(2878055..2878549) 1 NC_003143.1 hypothetical protein 2878549 1175394 YPO2563 Yersinia pestis CO92 hypothetical protein YP_002347524.1 2878055 R 214092 CDS YP_002347525.1 218929650 1175395 complement(2878857..2879312) 1 NC_003143.1 hypothetical protein 2879312 1175395 YPO2564 Yersinia pestis CO92 hypothetical protein YP_002347525.1 2878857 R 214092 CDS YP_002347526.1 218929651 1175396 2879553..2879744 1 NC_003143.1 hypothetical protein 2879744 1175396 YPO2565 Yersinia pestis CO92 hypothetical protein YP_002347526.1 2879553 D 214092 CDS YP_002347527.1 218929652 1175397 2879734..2880936 1 NC_003143.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 2880936 ackA 1175397 ackA Yersinia pestis CO92 acetate kinase YP_002347527.1 2879734 D 214092 CDS YP_002347528.1 218929653 1175398 2881104..2883257 1 NC_003143.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 2883257 pta 1175398 pta Yersinia pestis CO92 phosphate acetyltransferase YP_002347528.1 2881104 D 214092 CDS YP_002347529.1 218929654 1175399 complement(2883523..2884557) 1 NC_003143.1 LacI family transcriptional regulator 2884557 1175399 YPO2568 Yersinia pestis CO92 LacI family transcriptional regulator YP_002347529.1 2883523 R 214092 CDS YP_002347530.1 218929655 1175400 2884924..2885367 1 NC_003143.1 PTS system transporter subunit IIA 2885367 1175400 YPO2569 Yersinia pestis CO92 PTS system transporter subunit IIA YP_002347530.1 2884924 D 214092 CDS YP_008479719.1 537470182 1175401 2885536..2885790 1 NC_003143.1 PTS system transporter subunit IIB 2885790 1175401 YPO2569a Yersinia pestis CO92 PTS system transporter subunit IIB YP_008479719.1 2885536 D 214092 CDS YP_002347531.1 218929656 1175402 complement(2885812..2887020) 1 NC_003143.1 transposase for the IS285 insertion element 2887020 y1062 1175402 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002347531.1 2885812 R 214092 CDS YP_002347532.1 218929657 1175404 complement(2887989..2894003) 1 NC_003143.1 hypothetical protein 2894003 1175404 YPO2573 Yersinia pestis CO92 hypothetical protein YP_002347532.1 2887989 R 214092 CDS YP_002347533.1 218929658 1175405 complement(2894374..2894928) 1 NC_003143.1 No significant database matches to the full length CDS; hypothetical protein 2894928 1175405 YPO2574 Yersinia pestis CO92 hypothetical protein YP_002347533.1 2894374 R 214092 CDS YP_002347534.1 218929659 1175406 complement(2895617..2896471) 1 NC_003143.1 hypothetical protein 2896471 1175406 YPO2576 Yersinia pestis CO92 hypothetical protein YP_002347534.1 2895617 R 214092 CDS YP_002347535.1 218929660 1175407 2896777..2898303 1 NC_003143.1 aldehyde dehydrogenase 2898303 1175407 YPO2577 Yersinia pestis CO92 aldehyde dehydrogenase YP_002347535.1 2896777 D 214092 CDS YP_002347536.1 218929661 1175408 2898317..2900263 1 NC_003143.1 thiamine pyrophosphate-dependent protein 2900263 1175408 YPO2578 Yersinia pestis CO92 thiamine pyrophosphate-dependent protein YP_002347536.1 2898317 D 214092 CDS YP_002347537.1 218929662 1175410 2901668..2902597 1 NC_003143.1 sugar-binding protein 2902597 1175410 YPO2581 Yersinia pestis CO92 sugar-binding protein YP_002347537.1 2901668 D 214092 CDS YP_002347538.1 218929663 1175411 2902646..2904193 1 NC_003143.1 sugar transport ATP-binding protein 2904193 1175411 YPO2582 Yersinia pestis CO92 sugar transport ATP-binding protein YP_002347538.1 2902646 D 214092 CDS YP_002347539.1 218929664 1175412 2904205..2905233 1 NC_003143.1 sugar transport system permease 2905233 1175412 YPO2583 Yersinia pestis CO92 sugar transport system permease YP_002347539.1 2904205 D 214092 CDS YP_002347540.1 218929665 1175413 2905257..2906390 1 NC_003143.1 hypothetical protein 2906390 1175413 YPO2584 Yersinia pestis CO92 hypothetical protein YP_002347540.1 2905257 D 214092 CDS YP_002347541.1 218929666 1175414 2906422..2908392 1 NC_003143.1 carbohydrate kinase 2908392 1175414 YPO2585 Yersinia pestis CO92 carbohydrate kinase YP_002347541.1 2906422 D 214092 CDS YP_002347542.1 218929667 1175415 2908545..2909465 1 NC_003143.1 hypothetical protein 2909465 1175415 YPO2586 Yersinia pestis CO92 hypothetical protein YP_002347542.1 2908545 D 214092 CDS YP_002347543.1 218929668 1175416 2909475..2910290 1 NC_003143.1 hypothetical protein 2910290 1175416 YPO2587 Yersinia pestis CO92 hypothetical protein YP_002347543.1 2909475 D 214092 CDS YP_002347544.1 218929669 1175417 2910755..2912650 1 NC_003143.1 ABC transport protein 2912650 1175417 YPO2588 Yersinia pestis CO92 ABC transport protein YP_002347544.1 2910755 D 214092 CDS YP_002347545.1 218929670 1175418 complement(2912666..2912953) 1 NC_003143.1 hypothetical protein 2912953 1175418 YPO2589 Yersinia pestis CO92 hypothetical protein YP_002347545.1 2912666 R 214092 CDS YP_002347546.1 218929671 1175419 2913396..2913590 1 NC_003143.1 no significant database hits; hypothetical protein 2913590 1175419 YPO2590 Yersinia pestis CO92 hypothetical protein YP_002347546.1 2913396 D 214092 CDS YP_002347547.1 218929672 1175420 complement(2913608..2913790) 1 NC_003143.1 no significant database hits; hypothetical protein 2913790 1175420 YPO2591 Yersinia pestis CO92 hypothetical protein YP_002347547.1 2913608 R 214092 CDS YP_002347548.1 218929673 1175421 complement(2913972..2914937) 1 NC_003143.1 hypothetical protein 2914937 1175421 YPO2592 Yersinia pestis CO92 hypothetical protein YP_002347548.1 2913972 R 214092 CDS YP_002347549.1 218929674 1175422 2915360..2915977 1 NC_003143.1 LuxR family transcriptional regulator 2915977 1175422 YPO2593 Yersinia pestis CO92 LuxR family transcriptional regulator YP_002347549.1 2915360 D 214092 CDS YP_002347551.1 218929676 1175424 2917054..2917263 1 NC_003143.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 2917263 cspE 1175424 cspE Yersinia pestis CO92 cold shock protein CspE YP_002347551.1 2917054 D 214092 CDS YP_002347552.1 218929677 1175425 complement(2917686..2918069) 1 NC_003143.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 2918069 crcB 1175425 crcB Yersinia pestis CO92 camphor resistance protein CrcB YP_002347552.1 2917686 R 214092 CDS YP_002347553.1 218929678 1175426 2918636..2918893 1 NC_003143.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin-arginine translocation protein TatA 2918893 tatE 1175426 tatE Yersinia pestis CO92 twin-arginine translocation protein TatA YP_002347553.1 2918636 D 214092 CDS YP_002347554.1 218929679 1175427 complement(2919074..2920039) 1 NC_003143.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 2920039 lipA 1175427 lipA Yersinia pestis CO92 lipoyl synthase YP_002347554.1 2919074 R 214092 CDS YP_002347555.1 218929680 1175428 complement(2920232..2920921) 1 NC_003143.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 2920921 lipB 1175428 lipB Yersinia pestis CO92 lipoate-protein ligase B YP_002347555.1 2920232 R 214092 CDS YP_002347556.1 218929681 1175429 complement(2921145..2921408) 1 NC_003143.1 hypothetical protein 2921408 1175429 YPO2600 Yersinia pestis CO92 hypothetical protein YP_002347556.1 2921145 R 214092 CDS YP_002347557.1 218929682 1175430 complement(2921606..2922808) 1 NC_003143.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase fraction A 2922808 dacA 1175430 dacA Yersinia pestis CO92 D-alanyl-D-alanine carboxypeptidase fraction A YP_002347557.1 2921606 R 214092 CDS YP_002347558.1 218929683 1175431 complement(2923211..2924293) 1 NC_003143.1 rare lipoprotein A 2924293 rlpA 1175431 rlpA Yersinia pestis CO92 rare lipoprotein A YP_002347558.1 2923211 R 214092 CDS YP_002347559.1 218929684 1175432 complement(2924303..2925415) 1 NC_003143.1 cell wall shape-determining protein 2925415 rodA 1175432 rodA Yersinia pestis CO92 cell wall shape-determining protein YP_002347559.1 2924303 R 214092 CDS YP_002347560.1 218929685 1175433 complement(2925600..2927495) 1 NC_003143.1 penicillin-binding protein 2 2927495 pbpA 1175433 pbpA Yersinia pestis CO92 penicillin-binding protein 2 YP_002347560.1 2925600 R 214092 CDS YP_002347561.1 218929686 1175434 complement(2927577..2928047) 1 NC_003143.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2928047 1175434 YPO2605 Yersinia pestis CO92 rRNA large subunit methyltransferase YP_002347561.1 2927577 R 214092 CDS YP_002347562.1 218929687 1175435 complement(2928051..2928368) 1 NC_003143.1 hypothetical protein 2928368 1175435 YPO2606 Yersinia pestis CO92 hypothetical protein YP_002347562.1 2928051 R 214092 CDS YP_002347563.1 218929688 1175436 complement(2928592..2929254) 1 NC_003143.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 2929254 nadD 1175436 nadD Yersinia pestis CO92 nicotinic acid mononucleotide adenylyltransferase YP_002347563.1 2928592 R 214092 CDS YP_002347564.1 218929689 1175437 complement(2929244..2930278) 1 NC_003143.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 2930278 holA 1175437 holA Yersinia pestis CO92 DNA polymerase III subunit delta YP_002347564.1 2929244 R 214092 CDS YP_002347565.1 218929690 1175438 complement(2930275..2930898) 1 NC_003143.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 2930898 rlpB 1175438 rlpB Yersinia pestis CO92 LPS-assembly lipoprotein RlpB YP_002347565.1 2930275 R 214092 CDS YP_002347566.1 218929691 1175439 complement(2930913..2933495) 1 NC_003143.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 2933495 leuS 1175439 leuS Yersinia pestis CO92 leucyl-tRNA synthetase YP_002347566.1 2930913 R 214092 CDS YP_002347567.1 218929692 1175440 2933756..2934238 1 NC_003143.1 hypothetical protein 2934238 1175440 YPO2611 Yersinia pestis CO92 hypothetical protein YP_002347567.1 2933756 D 214092 CDS YP_002347568.1 218929693 1175441 complement(2934372..2935100) 1 NC_003143.1 glutamate/aspartate transport ATP-binding protein 2935100 gltL 1175441 gltL Yersinia pestis CO92 glutamate/aspartate transport ATP-binding protein YP_002347568.1 2934372 R 214092 CDS YP_002347569.1 218929694 1175442 complement(2935097..2935771) 1 NC_003143.1 glutamate/aspartate transport system permease 2935771 gltK 1175442 gltK Yersinia pestis CO92 glutamate/aspartate transport system permease YP_002347569.1 2935097 R 214092 CDS YP_002347570.1 218929695 1175443 complement(2935771..2936511) 1 NC_003143.1 glutamate/aspartate transport system permease 2936511 gltJ 1175443 gltJ Yersinia pestis CO92 glutamate/aspartate transport system permease YP_002347570.1 2935771 R 214092 CDS YP_002347571.1 218929696 1175444 complement(2936685..2937602) 1 NC_003143.1 glutamate and aspartate transporter subunit 2937602 glnH 1175444 glnH Yersinia pestis CO92 glutamate and aspartate transporter subunit YP_002347571.1 2936685 R 214092 CDS YP_002347572.1 218929697 1175445 complement(2938367..2939914) 1 NC_003143.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 2939914 lnt 1175445 lnt Yersinia pestis CO92 apolipoprotein N-acyltransferase YP_002347572.1 2938367 R 214092 CDS YP_002347573.1 218929698 1175446 complement(2939922..2940800) 1 NC_003143.1 hypothetical protein 2940800 ybeX 1175446 ybeX Yersinia pestis CO92 hypothetical protein YP_002347573.1 2939922 R 214092 CDS YP_002347574.1 218929699 1175447 complement(2940918..2941391) 1 NC_003143.1 metalloprotease 2941391 1175447 YPO2618 Yersinia pestis CO92 metalloprotease YP_002347574.1 2940918 R 214092 CDS YP_002347575.1 218929700 1175448 complement(2941388..2942500) 1 NC_003143.1 hypothetical protein 2942500 1175448 YPO2619 Yersinia pestis CO92 hypothetical protein YP_002347575.1 2941388 R 214092 CDS YP_002347576.1 218929701 1175449 complement(2942788..2944212) 1 NC_003143.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 2944212 miaB 1175449 miaB Yersinia pestis CO92 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002347576.1 2942788 R 214092 CDS YP_002347577.1 218929702 1175450 2944454..2945635 1 NC_003143.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 2945635 ubiF 1175450 ubiF Yersinia pestis CO92 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_002347577.1 2944454 D 214092 CDS YP_002347578.1 218929703 1175456 2946762..2946899 1 NC_003143.1 no significant database hits; hypothetical protein 2946899 1175456 YPO2622 Yersinia pestis CO92 hypothetical protein YP_002347578.1 2946762 D 214092 CDS YP_002347579.1 218929704 1175457 complement(2946948..2948612) 1 NC_003143.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 2948612 asnB 1175457 asnB Yersinia pestis CO92 asparagine synthetase B YP_002347579.1 2946948 R 214092 CDS YP_002347580.1 218929705 1175458 complement(2948967..2949719) 1 NC_003143.1 UMP phosphatase 2949719 nagD 1175458 nagD Yersinia pestis CO92 UMP phosphatase YP_002347580.1 2948967 R 214092 CDS YP_002347581.1 218929706 1175459 complement(2949792..2951021) 1 NC_003143.1 N-acetylglucosamine regulatory protein 2951021 nagC 1175459 nagC Yersinia pestis CO92 N-acetylglucosamine regulatory protein YP_002347581.1 2949792 R 214092 CDS YP_002347582.1 218929707 1175460 complement(2951035..2952180) 1 NC_003143.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 2952180 nagA 1175460 nagA Yersinia pestis CO92 N-acetylglucosamine-6-phosphate deacetylase YP_002347582.1 2951035 R 214092 CDS YP_002347583.1 218929708 1175461 complement(2952200..2953000) 1 NC_003143.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 2953000 nagB 1175461 nagB Yersinia pestis CO92 glucosamine-6-phosphate deaminase YP_002347583.1 2952200 R 214092 CDS YP_002347584.1 218929709 1175462 2953400..2955433 1 NC_003143.1 PTS system N-acetylglucosamine-specific transporter subunit IIABC 2955433 nagE 1175462 nagE Yersinia pestis CO92 PTS system N-acetylglucosamine-specific transporter subunit IIABC YP_002347584.1 2953400 D 214092 CDS YP_002347585.1 218929710 1175463 2955698..2956156 1 NC_003143.1 transposase for the IS1541 insertion element 2956156 tnp 1175463 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347585.1 2955698 D 214092 CDS YP_002347586.1 218929711 1175464 2956358..2958025 1 NC_003143.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 2958025 glnS 1175464 glnS Yersinia pestis CO92 glutaminyl-tRNA synthetase YP_002347586.1 2956358 D 214092 CDS YP_002347587.1 218929712 1175465 2958731..2960152 1 NC_003143.1 hypothetical protein 2960152 ybfM 1175465 ybfM Yersinia pestis CO92 hypothetical protein YP_002347587.1 2958731 D 214092 CDS YP_002347588.1 218929713 1175467 complement(2963585..2964031) 1 NC_003143.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 2964031 fur 1175467 fur Yersinia pestis CO92 ferric uptake regulator YP_002347588.1 2963585 R 214092 CDS YP_002347589.1 218929714 1175468 complement(2964398..2964925) 1 NC_003143.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 2964925 fldA 1175468 fldA Yersinia pestis CO92 flavodoxin FldA YP_002347589.1 2964398 R 214092 CDS YP_002347590.1 218929715 1175469 complement(2965342..2965629) 1 NC_003143.1 LexA regulated protein 2965629 1175469 YPO2637 Yersinia pestis CO92 LexA regulated protein YP_002347590.1 2965342 R 214092 CDS YP_002347591.1 218929716 1175470 complement(2965961..2966728) 1 NC_003143.1 hypothetical protein 2966728 1175470 YPO2638 Yersinia pestis CO92 hypothetical protein YP_002347591.1 2965961 R 214092 CDS YP_008479720.1 537470183 16744768 2967439..2967690 1 NC_003143.1 hypothetical protein 2967690 16744768 YPO2638a Yersinia pestis CO92 hypothetical protein YP_008479720.1 2967439 D 214092 CDS YP_002347593.1 218929718 1175472 complement(2968121..2968384) 1 NC_003143.1 IS1400 transposase A 2968384 1175472 YPO2640 Yersinia pestis CO92 IS1400 transposase A YP_002347593.1 2968121 R 214092 CDS YP_002347595.1 218929720 1175474 complement(2968931..2969713) 1 NC_003143.1 transposase/IS protein 2969713 1175474 YPO2642 Yersinia pestis CO92 transposase/IS protein YP_002347595.1 2968931 R 214092 CDS YP_002347596.1 218929721 1175475 complement(2969710..2970732) 1 NC_003143.1 transposase for insertion sequence IS100 2970732 y1093 1175475 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002347596.1 2969710 R 214092 CDS YP_002347597.1 218929722 1175477 complement(2971786..2972790) 1 NC_003143.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter substrate-binding protein 2972790 proX 1175477 proX Yersinia pestis CO92 glycine betaine transporter substrate-binding protein YP_002347597.1 2971786 R 214092 CDS YP_002347598.1 218929723 1175478 complement(2972838..2974004) 1 NC_003143.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 2974004 proW 1175478 proW Yersinia pestis CO92 glycine betaine transporter membrane protein YP_002347598.1 2972838 R 214092 CDS YP_002347599.1 218929724 1175479 complement(2973997..2975196) 1 NC_003143.1 glycine betaine/L-proline transport ATP-binding protein 2975196 proV 1175479 proV Yersinia pestis CO92 glycine betaine/L-proline transport ATP-binding protein YP_002347599.1 2973997 R 214092 CDS YP_002347600.1 218929725 1175480 complement(2975872..2976843) 1 NC_003143.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 2976843 nrdF 1175480 nrdF Yersinia pestis CO92 ribonucleotide-diphosphate reductase subunit beta YP_002347600.1 2975872 R 214092 CDS YP_002347601.1 218929726 1175481 complement(2976950..2979031) 1 NC_003143.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 2979031 nrdE 1175481 nrdE Yersinia pestis CO92 ribonucleotide-diphosphate reductase subunit alpha YP_002347601.1 2976950 R 214092 CDS YP_002347602.1 218929727 1175482 complement(2979082..2979486) 1 NC_003143.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 2979486 nrdI 1175482 nrdI Yersinia pestis CO92 ribonucleotide reductase stimulatory protein YP_002347602.1 2979082 R 214092 CDS YP_002347603.1 218929728 1175483 complement(2979500..2979736) 1 NC_003143.1 glutaredoxin 2979736 nrdH 1175483 nrdH Yersinia pestis CO92 glutaredoxin YP_002347603.1 2979500 R 214092 CDS YP_002347604.1 218929729 1175484 2980257..2980622 1 NC_003143.1 required for growth and survival under moderately acid conditions; acid shock protein 2980622 asr 1175484 asr Yersinia pestis CO92 acid shock protein YP_002347604.1 2980257 D 214092 CDS YP_002347605.1 218929730 1175485 2981100..2981435 1 NC_003143.1 hypothetical protein 2981435 1175485 YPO2653 Yersinia pestis CO92 hypothetical protein YP_002347605.1 2981100 D 214092 CDS YP_002347606.1 218929731 1175486 complement(2981533..2981982) 1 NC_003143.1 hypothetical protein 2981982 yicN 1175486 yicN Yersinia pestis CO92 hypothetical protein YP_002347606.1 2981533 R 214092 CDS YP_002347607.1 218929732 1175487 2982348..2983556 1 NC_003143.1 transposase for the IS285 insertion element 2983556 y1062 1175487 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002347607.1 2982348 D 214092 CDS YP_002347608.1 218929733 1175489 2984316..2984528 1 NC_003143.1 cold shock protein 2984528 cspB 1175489 cspB Yersinia pestis CO92 cold shock protein YP_002347608.1 2984316 D 214092 CDS YP_002347609.1 218929734 1175490 2985405..2986982 1 NC_003143.1 solute-binding protein 2986982 1175490 YPO2660 Yersinia pestis CO92 solute-binding protein YP_002347609.1 2985405 D 214092 CDS YP_002347610.1 218929735 1175491 2986979..2987950 1 NC_003143.1 hypothetical protein 2987950 1175491 YPO2661 Yersinia pestis CO92 hypothetical protein YP_002347610.1 2986979 D 214092 CDS YP_002347611.1 218929736 1175492 2987947..2988753 1 NC_003143.1 binding-protein-dependent transport protein 2988753 1175492 YPO2662 Yersinia pestis CO92 binding-protein-dependent transport protein YP_002347611.1 2987947 D 214092 CDS YP_002347612.1 218929737 1175493 2988753..2989559 1 NC_003143.1 transport ATPase 2989559 1175493 YPO2663 Yersinia pestis CO92 transport ATPase YP_002347612.1 2988753 D 214092 CDS YP_002347613.1 218929738 1175494 2989552..2990217 1 NC_003143.1 transport ATPase 2990217 1175494 YPO2664 Yersinia pestis CO92 transport ATPase YP_002347613.1 2989552 D 214092 CDS YP_002347614.1 218929739 1175495 2991416..2991718 1 NC_003143.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 2991718 ureA 1175495 ureA Yersinia pestis CO92 urease subunit gamma YP_002347614.1 2991416 D 214092 CDS YP_002347615.1 218929740 1175496 2991771..2992205 1 NC_003143.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); urease subunit beta 2992205 ureB 1175496 ureB Yersinia pestis CO92 urease subunit beta YP_002347615.1 2991771 D 214092 CDS YP_002347616.1 218929741 1175497 2992295..2994013 1 NC_003143.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 2994013 ureC 1175497 ureC Yersinia pestis CO92 urease subunit alpha YP_002347616.1 2992295 D 214092 CDS YP_002347617.1 218929742 1175498 2994309..2995004 1 NC_003143.1 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 2995004 ureE 1175498 ureE Yersinia pestis CO92 urease accessory protein UreE YP_002347617.1 2994309 D 214092 CDS YP_002347618.1 218929743 1175499 2995026..2995712 1 NC_003143.1 urease accessory protein 2995712 ureF 1175499 ureF Yersinia pestis CO92 urease accessory protein YP_002347618.1 2995026 D 214092 CDS YP_002347619.1 218929744 1175500 2995839..2996501 1 NC_003143.1 urease accessory protein 2996501 ureG 1175500 ureG Yersinia pestis CO92 urease accessory protein YP_002347619.1 2995839 D 214092 CDS YP_002347620.1 218929745 1175502 2997656..2998648 1 NC_003143.1 urea transporter 2998648 1175502 YPO2672 Yersinia pestis CO92 urea transporter YP_002347620.1 2997656 D 214092 CDS YP_002347621.1 218929746 1175503 2998797..2999855 1 NC_003143.1 nickel transport protein 2999855 1175503 YPO2673 Yersinia pestis CO92 nickel transport protein YP_002347621.1 2998797 D 214092 CDS YP_002347622.1 218929747 1175504 complement(3000024..3000353) 1 NC_003143.1 acid-resistance protein 3000353 hdeB 1175504 hdeB Yersinia pestis CO92 acid-resistance protein YP_002347622.1 3000024 R 214092 CDS YP_002347623.1 218929748 1175505 3000971..3002146 1 NC_003143.1 voltage-gated potassium channel 3002146 1175505 YPO2675 Yersinia pestis CO92 voltage-gated potassium channel YP_002347623.1 3000971 D 214092 CDS YP_002347624.1 218929749 1175506 complement(3002244..3002648) 1 NC_003143.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 3002648 ccrB 1175506 ccrB Yersinia pestis CO92 camphor resistance protein CrcB YP_002347624.1 3002244 R 214092 CDS YP_002347625.1 218929750 1175507 complement(3002664..3003044) 1 NC_003143.1 hypothetical protein 3003044 1175507 YPO2677 Yersinia pestis CO92 hypothetical protein YP_002347625.1 3002664 R 214092 CDS YP_008479721.1 537470184 16744770 complement(3003133..3003312) 1 NC_003143.1 hypothetical protein 3003312 16744770 YPO2677a Yersinia pestis CO92 hypothetical protein YP_008479721.1 3003133 R 214092 CDS YP_002347626.1 218929751 1175508 3004085..3004402 1 NC_003143.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 3004402 celA 1175508 celA Yersinia pestis CO92 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_002347626.1 3004085 D 214092 CDS YP_002347627.1 218929752 1175509 3004413..3005774 1 NC_003143.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 3005774 celB 1175509 celB Yersinia pestis CO92 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_002347627.1 3004413 D 214092 CDS YP_002347628.1 218929753 1175510 3005941..3006288 1 NC_003143.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 3006288 celC 1175510 celC Yersinia pestis CO92 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_002347628.1 3005941 D 214092 CDS YP_002347629.1 218929754 1175511 3006325..3007167 1 NC_003143.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 3007167 celD 1175511 celD Yersinia pestis CO92 DNA-binding transcriptional regulator ChbR YP_002347629.1 3006325 D 214092 CDS YP_002347630.1 218929755 1175512 3007219..3007980 1 NC_003143.1 hypothetical protein 3007980 1175512 YPO2682 Yersinia pestis CO92 hypothetical protein YP_002347630.1 3007219 D 214092 CDS YP_002347631.1 218929756 1175513 complement(3007987..3008163) 1 NC_003143.1 no significant database hits to the full length CDS; hypothetical protein 3008163 1175513 YPO2683 Yersinia pestis CO92 hypothetical protein YP_002347631.1 3007987 R 214092 CDS YP_002347632.1 218929757 1175514 complement(3008275..3008643) 1 NC_003143.1 hypothetical protein 3008643 1175514 YPO2684 Yersinia pestis CO92 hypothetical protein YP_002347632.1 3008275 R 214092 CDS YP_002347633.1 218929758 1175515 3009138..3009665 1 NC_003143.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 3009665 seqA 1175515 seqA Yersinia pestis CO92 replication initiation regulator SeqA YP_002347633.1 3009138 D 214092 CDS YP_002347634.1 218929759 1175516 3009738..3011381 1 NC_003143.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 3011381 pgm 1175516 pgm Yersinia pestis CO92 phosphoglucomutase YP_002347634.1 3009738 D 214092 CDS YP_008479722.1 537470185 16744771 3011755..3011997 1 NC_003143.1 hypothetical protein 3011997 16744771 YPO2686a Yersinia pestis CO92 hypothetical protein YP_008479722.1 3011755 D 214092 CDS YP_002347635.1 218929760 1175517 complement(3012125..3012553) 1 NC_003143.1 hypothetical protein 3012553 1175517 YPO2687 Yersinia pestis CO92 hypothetical protein YP_002347635.1 3012125 R 214092 CDS YP_002347636.1 218929761 1175518 complement(3012648..3013277) 1 NC_003143.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 3013277 kdpE 1175518 kdpE Yersinia pestis CO92 DNA-binding transcriptional activator KdpE YP_002347636.1 3012648 R 214092 CDS YP_002347637.1 218929762 1175519 complement(3013570..3016296) 1 NC_003143.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 3016296 kdpD 1175519 kdpD Yersinia pestis CO92 sensor protein KdpD YP_002347637.1 3013570 R 214092 CDS YP_002347638.1 218929763 1175520 complement(3016306..3016908) 1 NC_003143.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 3016908 kdpC 1175520 kdpC Yersinia pestis CO92 potassium-transporting ATPase subunit C YP_002347638.1 3016306 R 214092 CDS YP_002347639.1 218929764 1175521 complement(3017120..3019186) 1 NC_003143.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 3019186 kdpB 1175521 kdpB Yersinia pestis CO92 potassium-transporting ATPase subunit B YP_002347639.1 3017120 R 214092 CDS YP_002347640.1 218929765 1175522 complement(3019280..3020968) 1 NC_003143.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 3020968 kdpA 1175522 kdpA Yersinia pestis CO92 potassium-transporting ATPase subunit A YP_002347640.1 3019280 R 214092 CDS YP_002347641.1 218929766 1175523 3021463..3021669 1 NC_003143.1 hypothetical protein 3021669 ybfA 1175523 ybfA Yersinia pestis CO92 hypothetical protein YP_002347641.1 3021463 D 214092 CDS YP_002347642.1 218929767 1175524 3022008..3022490 1 NC_003143.1 hypothetical protein 3022490 1175524 YPO2694 Yersinia pestis CO92 hypothetical protein YP_002347642.1 3022008 D 214092 CDS YP_002347643.1 218929768 1175525 3022620..3024083 1 NC_003143.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 3024083 phrB 1175525 phrB Yersinia pestis CO92 deoxyribodipyrimidine photolyase YP_002347643.1 3022620 D 214092 CDS YP_002347644.1 218929769 1175526 3024080..3025111 1 NC_003143.1 3',5'-cyclic-nucleotide phosphodiesterase 3025111 1175526 YPO2696 Yersinia pestis CO92 3',5'-cyclic-nucleotide phosphodiesterase YP_002347644.1 3024080 D 214092 CDS YP_002347645.1 218929770 1175527 3025234..3025980 1 NC_003143.1 hydrolase-oxidase 3025980 1175527 YPO2697 Yersinia pestis CO92 hydrolase-oxidase YP_002347645.1 3025234 D 214092 CDS YP_002347646.1 218929771 1175529 3027249..3028199 1 NC_003143.1 hypothetical protein 3028199 1175529 YPO2699 Yersinia pestis CO92 hypothetical protein YP_002347646.1 3027249 D 214092 CDS YP_002347647.1 218929772 1175530 3028196..3028933 1 NC_003143.1 LamB/YcsF family protein 3028933 1175530 YPO2700 Yersinia pestis CO92 LamB/YcsF family protein YP_002347647.1 3028196 D 214092 CDS YP_002347648.1 218929773 1175531 3029018..3029749 1 NC_003143.1 hypothetical protein 3029749 1175531 YPO2701 Yersinia pestis CO92 hypothetical protein YP_002347648.1 3029018 D 214092 CDS YP_002347649.1 218929774 1175532 3029746..3030765 1 NC_003143.1 hypothetical protein 3030765 1175532 YPO2702 Yersinia pestis CO92 hypothetical protein YP_002347649.1 3029746 D 214092 CDS YP_002347650.1 218929775 1175533 3030775..3031422 1 NC_003143.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 3031422 pcp 1175533 pcp Yersinia pestis CO92 pyrrolidone-carboxylate peptidase YP_002347650.1 3030775 D 214092 CDS YP_002347651.1 218929776 1175534 complement(3031513..3032199) 1 NC_003143.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 3032199 ung 1175534 ung Yersinia pestis CO92 uracil-DNA glycosylase YP_002347651.1 3031513 R 214092 CDS YP_002347652.1 218929777 1175535 3032552..3032935 1 NC_003143.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 3032935 1175535 YPO2705 Yersinia pestis CO92 autonomous glycyl radical cofactor GrcA YP_002347652.1 3032552 D 214092 CDS YP_002347653.1 218929778 1175536 3033114..3034076 1 NC_003143.1 phospholipase A 3034076 plaA 1175536 plaA Yersinia pestis CO92 phospholipase A YP_002347653.1 3033114 D 214092 CDS YP_002347654.1 218929779 1175537 3034154..3034810 1 NC_003143.1 phospholipase A accessory protein 3034810 yplB 1175537 yplB Yersinia pestis CO92 phospholipase A accessory protein YP_002347654.1 3034154 D 214092 CDS YP_002347655.1 218929780 1175538 complement(3034941..3036266) 1 NC_003143.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 3036266 srmB 1175538 srmB Yersinia pestis CO92 ATP-dependent RNA helicase SrmB YP_002347655.1 3034941 R 214092 CDS YP_002347656.1 218929781 1175539 3036506..3037264 1 NC_003143.1 hypothetical protein 3037264 1175539 YPO2709 Yersinia pestis CO92 hypothetical protein YP_002347656.1 3036506 D 214092 CDS YP_002347657.1 218929782 1175540 complement(3037547..3039184) 1 NC_003143.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 3039184 nadB 1175540 nadB Yersinia pestis CO92 L-aspartate oxidase YP_002347657.1 3037547 R 214092 CDS YP_002347658.1 218929783 1175541 3039372..3039947 1 NC_003143.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 3039947 rpoE 1175541 rpoE Yersinia pestis CO92 RNA polymerase sigma factor RpoE YP_002347658.1 3039372 D 214092 CDS YP_002347659.1 218929784 1175542 3039973..3040629 1 NC_003143.1 anti-RNA polymerase sigma factor SigE 3040629 rseA 1175542 rseA Yersinia pestis CO92 anti-RNA polymerase sigma factor SigE YP_002347659.1 3039973 D 214092 CDS YP_002347660.1 218929785 1175543 3040629..3041585 1 NC_003143.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 3041585 rseB 1175543 rseB Yersinia pestis CO92 periplasmic negative regulator of sigmaE YP_002347660.1 3040629 D 214092 CDS YP_002347661.1 218929786 1175544 3041582..3042037 1 NC_003143.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 3042037 rseC 1175544 rseC Yersinia pestis CO92 SoxR reducing system protein RseC YP_002347661.1 3041582 D 214092 CDS YP_002347662.1 218929787 1175545 complement(3042058..3042912) 1 NC_003143.1 hypothetical protein 3042912 lepA 1175545 lepA Yersinia pestis CO92 hypothetical protein YP_002347662.1 3042058 R 214092 CDS YP_002347663.1 218929788 1175546 3043412..3045211 1 NC_003143.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 3045211 lepA 1175546 lepA Yersinia pestis CO92 GTP-binding protein LepA YP_002347663.1 3043412 D 214092 CDS YP_002347664.1 218929789 1175547 3045221..3046219 1 NC_003143.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 3046219 lepB 1175547 lepB Yersinia pestis CO92 signal peptidase I YP_002347664.1 3045221 D 214092 CDS YP_002347665.1 218929790 1175548 3046571..3047251 1 NC_003143.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 3047251 rnc 1175548 rnc Yersinia pestis CO92 ribonuclease III YP_002347665.1 3046571 D 214092 CDS YP_002347666.1 218929791 1175549 3047248..3048159 1 NC_003143.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 3048159 era 1175549 era Yersinia pestis CO92 GTP-binding protein Era YP_002347666.1 3047248 D 214092 CDS YP_002347667.1 218929792 1175550 3048169..3048894 1 NC_003143.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 3048894 recO 1175550 recO Yersinia pestis CO92 DNA repair protein RecO YP_002347667.1 3048169 D 214092 CDS YP_002347668.1 218929793 1175551 3049021..3050043 1 NC_003143.1 transposase for insertion sequence IS100 3050043 y1093 1175551 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002347668.1 3049021 D 214092 CDS YP_002347669.1 218929794 1175552 3050040..3050822 1 NC_003143.1 transposase/IS protein 3050822 1175552 YPO2722 Yersinia pestis CO92 transposase/IS protein YP_002347669.1 3050040 D 214092 CDS YP_002347671.1 218929796 1175554 3051683..3055510 1 NC_003143.1 hypothetical protein 3055510 1175554 YPO2724 Yersinia pestis CO92 hypothetical protein YP_002347671.1 3051683 D 214092 CDS YP_002347672.1 218929797 1175555 3055804..3058569 1 NC_003143.1 hypothetical protein 3058569 1175555 YPO2725 Yersinia pestis CO92 hypothetical protein YP_002347672.1 3055804 D 214092 CDS YP_002347673.1 218929798 1175556 3058928..3059776 1 NC_003143.1 hypothetical protein 3059776 1175556 YPO2726 Yersinia pestis CO92 hypothetical protein YP_002347673.1 3058928 D 214092 CDS YP_002347674.1 218929799 1175557 3059796..3060602 1 NC_003143.1 hypothetical protein 3060602 1175557 YPO2727 Yersinia pestis CO92 hypothetical protein YP_002347674.1 3059796 D 214092 CDS YP_002347675.1 218929800 1175558 3060699..3061178 1 NC_003143.1 hypothetical protein 3061178 1175558 YPO2728 Yersinia pestis CO92 hypothetical protein YP_002347675.1 3060699 D 214092 CDS YP_002347676.1 218929801 1175559 3061203..3061550 1 NC_003143.1 hypothetical protein 3061550 1175559 YPO2729 Yersinia pestis CO92 hypothetical protein YP_002347676.1 3061203 D 214092 CDS YP_002347677.1 218929802 1175560 complement(3061607..3061948) 1 NC_003143.1 hypothetical protein 3061948 1175560 YPO2730 Yersinia pestis CO92 hypothetical protein YP_002347677.1 3061607 R 214092 CDS YP_002347678.1 218929803 1175561 complement(3062324..3064363) 1 NC_003143.1 hypothetical protein 3064363 1175561 YPO2731 Yersinia pestis CO92 hypothetical protein YP_002347678.1 3062324 R 214092 CDS YP_002347679.1 218929804 1175562 complement(3064368..3064910) 1 NC_003143.1 hypothetical protein 3064910 lemA 1175562 lemA Yersinia pestis CO92 hypothetical protein YP_002347679.1 3064368 R 214092 CDS YP_002347680.1 218929805 1175564 3065526..3065993 1 NC_003143.1 No significant database matches. CDS DNA has a low GC content, 35.47%.; hypothetical protein 3065993 1175564 YPO2733 Yersinia pestis CO92 hypothetical protein YP_002347680.1 3065526 D 214092 CDS YP_002347681.1 218929806 1175565 3066438..3067094 1 NC_003143.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 3067094 ccmA 1175565 ccmA Yersinia pestis CO92 cytochrome c biogenesis protein CcmA YP_002347681.1 3066438 D 214092 CDS YP_002347682.1 218929807 1175566 3067064..3067723 1 NC_003143.1 heme exporter protein B 3067723 ccmB 1175566 ccmB Yersinia pestis CO92 heme exporter protein B YP_002347682.1 3067064 D 214092 CDS YP_002347683.1 218929808 1175567 3067786..3068523 1 NC_003143.1 heme exporter protein C 3068523 ccmC 1175567 ccmC Yersinia pestis CO92 heme exporter protein C YP_002347683.1 3067786 D 214092 CDS YP_002347684.1 218929809 1175568 3068520..3068822 1 NC_003143.1 heme exporter protein D 3068822 ccmD 1175568 ccmD Yersinia pestis CO92 heme exporter protein D YP_002347684.1 3068520 D 214092 CDS YP_002347685.1 218929810 1175569 3068819..3069313 1 NC_003143.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 3069313 ccmE 1175569 ccmE Yersinia pestis CO92 cytochrome c-type biogenesis protein CcmE YP_002347685.1 3068819 D 214092 CDS YP_002347686.1 218929811 1175570 3069310..3071280 1 NC_003143.1 cytochrome c-type biogenesis protein 3071280 ccmF 1175570 ccmF Yersinia pestis CO92 cytochrome c-type biogenesis protein YP_002347686.1 3069310 D 214092 CDS YP_002347687.1 218929812 1175571 3071277..3071843 1 NC_003143.1 thiol:disulfide interchange protein DsbE 3071843 ccmG 1175571 ccmG Yersinia pestis CO92 thiol:disulfide interchange protein DsbE YP_002347687.1 3071277 D 214092 CDS YP_002347688.1 218929813 1175572 3071840..3072352 1 NC_003143.1 cytochrome c-type biogenesis protein 3072352 ccmH 1175572 ccmH Yersinia pestis CO92 cytochrome c-type biogenesis protein YP_002347688.1 3071840 D 214092 CDS YP_002347689.1 218929814 1175573 3072352..3073578 1 NC_003143.1 cytochrome c-type biogenesis protein 3073578 1175573 YP02742 Yersinia pestis CO92 cytochrome c-type biogenesis protein YP_002347689.1 3072352 D 214092 CDS YP_002347690.1 218929815 1175574 3073614..3074378 1 NC_003143.1 VacJ lipoprotein 3074378 vacJ 1175574 vacJ Yersinia pestis CO92 VacJ lipoprotein YP_002347690.1 3073614 D 214092 CDS YP_002347691.1 218929816 1175575 complement(3074485..3075756) 1 NC_003143.1 long-chain fatty acid outer membrane transporter 3075756 fadL 1175575 fadL Yersinia pestis CO92 long-chain fatty acid outer membrane transporter YP_002347691.1 3074485 R 214092 CDS YP_002347692.1 218929817 1175576 3076164..3076460 1 NC_003143.1 hypothetical protein 3076460 1175576 YPO2745 Yersinia pestis CO92 hypothetical protein YP_002347692.1 3076164 D 214092 CDS YP_002347693.1 218929818 1175577 3076747..3078057 1 NC_003143.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 3078057 fadI 1175577 fadI Yersinia pestis CO92 3-ketoacyl-CoA thiolase YP_002347693.1 3076747 D 214092 CDS YP_002347694.1 218929819 1175578 3078057..3080381 1 NC_003143.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 3080381 fadJ 1175578 fadJ Yersinia pestis CO92 multifunctional fatty acid oxidation complex subunit alpha YP_002347694.1 3078057 D 214092 CDS YP_002347695.1 218929820 1175579 3080950..3081441 1 NC_003143.1 phosphohistidine phosphatase 3081441 sixA 1175579 sixA Yersinia pestis CO92 phosphohistidine phosphatase YP_002347695.1 3080950 D 214092 CDS YP_002347696.1 218929821 1175580 complement(3081827..3082357) 1 NC_003143.1 hypothetical protein 3082357 1175580 YPO2749 Yersinia pestis CO92 hypothetical protein YP_002347696.1 3081827 R 214092 CDS YP_002347697.1 218929822 1175581 3082727..3083659 1 NC_003143.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 3083659 1175581 YPO2750 Yersinia pestis CO92 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002347697.1 3082727 D 214092 CDS YP_002347698.1 218929823 1175582 3083736..3084821 1 NC_003143.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 3084821 aroC 1175582 aroC Yersinia pestis CO92 chorismate synthase YP_002347698.1 3083736 D 214092 CDS YP_002347699.1 218929824 1175583 3084827..3085654 1 NC_003143.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 3085654 mepA 1175583 mepA Yersinia pestis CO92 penicillin-insensitive murein endopeptidase YP_002347699.1 3084827 D 214092 CDS YP_002347700.1 218929825 1175584 3085658..3086464 1 NC_003143.1 hypothetical protein 3086464 yfcA 1175584 yfcA Yersinia pestis CO92 hypothetical protein YP_002347700.1 3085658 D 214092 CDS YP_002347701.1 218929826 1175585 3086564..3087106 1 NC_003143.1 hypothetical protein 3087106 1175585 YPO2754 Yersinia pestis CO92 hypothetical protein YP_002347701.1 3086564 D 214092 CDS YP_002347702.1 218929827 1175586 3087164..3087442 1 NC_003143.1 hypothetical protein 3087442 1175586 YPO2755 Yersinia pestis CO92 hypothetical protein YP_002347702.1 3087164 D 214092 CDS YP_002347703.1 218929828 1175587 complement(3087620..3089689) 1 NC_003143.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 3089689 mnmC 1175587 mnmC Yersinia pestis CO92 5-methylaminomethyl-2-thiouridine methyltransferase YP_002347703.1 3087620 R 214092 CDS YP_002347704.1 218929829 1175588 3089861..3091084 1 NC_003143.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 3091084 fabB 1175588 fabB Yersinia pestis CO92 3-oxoacyl-ACP synthase YP_002347704.1 3089861 D 214092 CDS YP_002347705.1 218929830 1175589 complement(3091492..3092187) 1 NC_003143.1 aspartate/glutamate racemase 3092187 1175589 YPO2758 Yersinia pestis CO92 aspartate/glutamate racemase YP_002347705.1 3091492 R 214092 CDS YP_002347706.1 218929831 1175590 3092975..3093505 1 NC_003143.1 mannose-resistant fimbrial protein 3093505 mrpA 1175590 mrpA Yersinia pestis CO92 mannose-resistant fimbrial protein YP_002347706.1 3092975 D 214092 CDS YP_002347707.1 218929832 1175591 complement(3093847..3094884) 1 NC_003143.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 3094884 flk 1175591 flk Yersinia pestis CO92 flagella biosynthesis regulator YP_002347707.1 3093847 R 214092 CDS YP_002347708.1 218929833 1175592 complement(3095169..3096086) 1 NC_003143.1 hypothetical protein 3096086 1175592 YPO2761 Yersinia pestis CO92 hypothetical protein YP_002347708.1 3095169 R 214092 CDS YP_002347709.1 218929834 1175593 3096312..3097097 1 NC_003143.1 AraC family transcriptional regulator 3097097 1175593 YPO2762 Yersinia pestis CO92 AraC family transcriptional regulator YP_002347709.1 3096312 D 214092 CDS YP_002347710.1 218929835 1175594 3097144..3098271 1 NC_003143.1 D-isomer specific 2-hydroxyacid dehydrogenase 3098271 pdxB 1175594 pdxB Yersinia pestis CO92 D-isomer specific 2-hydroxyacid dehydrogenase YP_002347710.1 3097144 D 214092 CDS YP_002347711.1 218929836 1175595 complement(3098415..3098873) 1 NC_003143.1 transposase for the IS1541 insertion element 3098873 tnp 1175595 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347711.1 3098415 R 214092 CDS YP_002347712.1 218929837 1175596 3099152..3100162 1 NC_003143.1 semialdehyde dehydrogenase 3100162 asd 1175596 asd Yersinia pestis CO92 semialdehyde dehydrogenase YP_002347712.1 3099152 D 214092 CDS YP_002347713.1 218929838 1175597 3100249..3101043 1 NC_003143.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 3101043 truA 1175597 truA Yersinia pestis CO92 tRNA pseudouridine synthase A YP_002347713.1 3100249 D 214092 CDS YP_002347714.1 218929839 1175598 3101200..3101862 1 NC_003143.1 hypothetical protein 3101862 dedA 1175598 dedA Yersinia pestis CO92 hypothetical protein YP_002347714.1 3101200 D 214092 CDS YP_002347715.1 218929840 1175599 3102093..3103007 1 NC_003143.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 3103007 accD 1175599 accD Yersinia pestis CO92 acetyl-CoA carboxylase subunit beta YP_002347715.1 3102093 D 214092 CDS YP_002347716.1 218929841 1175600 3103256..3104560 1 NC_003143.1 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase 3104560 folC 1175600 folC Yersinia pestis CO92 bifunctional folylpolyglutamate synthase/ dihydrofolate synthase YP_002347716.1 3103256 D 214092 CDS YP_002347717.1 218929842 1175601 3104680..3105402 1 NC_003143.1 hypothetical protein 3105402 dedD 1175601 dedD Yersinia pestis CO92 hypothetical protein YP_002347717.1 3104680 D 214092 CDS YP_002347718.1 218929843 1175602 3105714..3106223 1 NC_003143.1 membrane protein required for colicin V production; colicin V production protein 3106223 cvpA 1175602 cvpA Yersinia pestis CO92 colicin V production protein YP_002347718.1 3105714 D 214092 CDS YP_002347719.1 218929844 1175603 3106236..3107753 1 NC_003143.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 3107753 purF 1175603 purF Yersinia pestis CO92 amidophosphoribosyltransferase YP_002347719.1 3106236 D 214092 CDS YP_002347720.1 218929845 1175604 3108000..3108572 1 NC_003143.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 3108572 ubiX 1175604 ubiX Yersinia pestis CO92 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002347720.1 3108000 D 214092 CDS YP_002347721.1 218929846 1175605 3109091..3109879 1 NC_003143.1 histidine-binding periplasmic protein 3109879 hisJ 1175605 hisJ Yersinia pestis CO92 histidine-binding periplasmic protein YP_002347721.1 3109091 D 214092 CDS YP_002347722.1 218929847 1175606 3109982..3110668 1 NC_003143.1 histidine transport system permease HisQ 3110668 hisQ 1175606 hisQ Yersinia pestis CO92 histidine transport system permease HisQ YP_002347722.1 3109982 D 214092 CDS YP_002347723.1 218929848 1175607 3110665..3111381 1 NC_003143.1 histidine transport system permease HisM 3111381 hisM 1175607 hisM Yersinia pestis CO92 histidine transport system permease HisM YP_002347723.1 3110665 D 214092 CDS YP_002347724.1 218929849 1175608 3111395..3112192 1 NC_003143.1 histidine/lysine/arginine/ornithine transporter subunit 3112192 hisP 1175608 hisP Yersinia pestis CO92 histidine/lysine/arginine/ornithine transporter subunit YP_002347724.1 3111395 D 214092 CDS YP_002347725.1 218929850 1175609 complement(3112316..3113224) 1 NC_003143.1 hypothetical protein 3113224 1175609 YPO2778 Yersinia pestis CO92 hypothetical protein YP_002347725.1 3112316 R 214092 CDS YP_002347726.1 218929851 1175610 3113572..3114270 1 NC_003143.1 hypothetical protein 3114270 1175610 YPO2779 Yersinia pestis CO92 hypothetical protein YP_002347726.1 3113572 D 214092 CDS YP_002347727.1 218929852 1175611 3114471..3115046 1 NC_003143.1 phosphodiesterase 3115046 1175611 YPO2780 Yersinia pestis CO92 phosphodiesterase YP_002347727.1 3114471 D 214092 CDS YP_002347728.1 218929853 1175612 3115268..3115816 1 NC_003143.1 hypothetical protein 3115816 1175612 YPO2781 Yersinia pestis CO92 hypothetical protein YP_002347728.1 3115268 D 214092 CDS YP_002347729.1 218929854 1175613 complement(3115933..3117189) 1 NC_003143.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 3117189 ulaA 1175613 ulaA Yersinia pestis CO92 PTS system ascorbate-specific transporter subunit IIC YP_002347729.1 3115933 R 214092 CDS YP_002347730.1 218929855 1175614 3117329..3118537 1 NC_003143.1 transposase for the IS285 insertion element 3118537 y1062 1175614 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002347730.1 3117329 D 214092 CDS YP_002347731.1 218929856 1175616 complement(3120316..3120561) 1 NC_003143.1 DNA-binding protein 3120561 nlp 1175616 nlp Yersinia pestis CO92 DNA-binding protein YP_002347731.1 3120316 R 214092 CDS YP_002347733.1 218929858 1175618 3122083..3122484 1 NC_003143.1 hypothetical protein 3122484 1175618 YPO2790 Yersinia pestis CO92 hypothetical protein YP_002347733.1 3122083 D 214092 CDS YP_002347734.1 218929859 1175619 3122738..3123118 1 NC_003143.1 hypothetical protein 3123118 1175619 YPO2792 Yersinia pestis CO92 hypothetical protein YP_002347734.1 3122738 D 214092 CDS YP_002347735.1 218929860 1175620 complement(3123130..3123702) 1 NC_003143.1 hypothetical protein 3123702 1175620 YPO2793 Yersinia pestis CO92 hypothetical protein YP_002347735.1 3123130 R 214092 CDS YP_002347736.1 218929861 1175621 complement(3123726..3123977) 1 NC_003143.1 no significant database hits; hypothetical protein 3123977 1175621 YPO2794 Yersinia pestis CO92 hypothetical protein YP_002347736.1 3123726 R 214092 CDS YP_002347737.1 218929862 1175622 complement(3124016..3124255) 1 NC_003143.1 hypothetical protein 3124255 1175622 YPO2795 Yersinia pestis CO92 hypothetical protein YP_002347737.1 3124016 R 214092 CDS YP_002347738.1 218929863 1175623 3125064..3126980 1 NC_003143.1 autotransporter protein 3126980 yapC 1175623 yapC Yersinia pestis CO92 autotransporter protein YP_002347738.1 3125064 D 214092 CDS YP_002347739.1 218929864 1175624 3127515..3128096 1 NC_003143.1 no significant database hits; hypothetical protein 3128096 1175624 YPO2797 Yersinia pestis CO92 hypothetical protein YP_002347739.1 3127515 D 214092 CDS YP_002347741.1 218929866 1175626 complement(3128498..3129706) 1 NC_003143.1 transposase for the IS285 insertion element 3129706 y1062 1175626 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002347741.1 3128498 R 214092 CDS YP_002347742.1 218929867 1175627 3130158..3132365 1 NC_003143.1 hypothetical protein 3132365 1175627 YPO2801 Yersinia pestis CO92 hypothetical protein YP_002347742.1 3130158 D 214092 CDS YP_002347743.1 218929868 1175628 3132358..3132888 1 NC_003143.1 hypothetical protein 3132888 1175628 YPO2802 Yersinia pestis CO92 hypothetical protein YP_002347743.1 3132358 D 214092 CDS YP_002347744.1 218929869 1175629 3133047..3135428 1 NC_003143.1 beta-glucosidase 3135428 bglB 1175629 bglB Yersinia pestis CO92 beta-glucosidase YP_002347744.1 3133047 D 214092 CDS YP_002347745.1 218929870 1175630 complement(3135507..3137135) 1 NC_003143.1 no significant database hits; hypothetical protein 3137135 1175630 YPO2804 Yersinia pestis CO92 hypothetical protein YP_002347745.1 3135507 R 214092 CDS YP_002347746.1 218929871 1175631 3137566..3138459 1 NC_003143.1 aldo/keto reductase 3138459 1175631 YPO2805 Yersinia pestis CO92 aldo/keto reductase YP_002347746.1 3137566 D 214092 CDS YP_002347747.1 218929872 1175632 3138485..3139474 1 NC_003143.1 aldo/keto reductase 3139474 1175632 YPO2806 Yersinia pestis CO92 aldo/keto reductase YP_002347747.1 3138485 D 214092 CDS YP_002347748.1 218929873 1175633 complement(3139529..3140422) 1 NC_003143.1 LysR family transcriptional regulator 3140422 ptxR 1175633 ptxR Yersinia pestis CO92 LysR family transcriptional regulator YP_002347748.1 3139529 R 214092 CDS YP_002347749.1 218929874 1175634 3140516..3141538 1 NC_003143.1 transposase for insertion sequence IS100 3141538 y1093 1175634 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002347749.1 3140516 D 214092 CDS YP_002347750.1 218929875 1175635 3141535..3142317 1 NC_003143.1 transposase/IS protein 3142317 1175635 YPO2809 Yersinia pestis CO92 transposase/IS protein YP_002347750.1 3141535 D 214092 CDS YP_002347751.1 218929876 1175636 complement(3142684..3142989) 1 NC_003143.1 hypothetical protein 3142989 1175636 YPO2811 Yersinia pestis CO92 hypothetical protein YP_002347751.1 3142684 R 214092 CDS YP_002347752.1 218929877 1175637 complement(3143086..3143457) 1 NC_003143.1 Doubtful CDS, no significant database matches; hypothetical protein 3143457 1175637 YPO2812 Yersinia pestis CO92 hypothetical protein YP_002347752.1 3143086 R 214092 CDS YP_002347753.1 218929878 1175638 complement(3143469..3144788) 1 NC_003143.1 dual specificity phosphatase 3144788 ynbD 1175638 ynbD Yersinia pestis CO92 dual specificity phosphatase YP_002347753.1 3143469 R 214092 CDS YP_002347754.1 218929879 1175639 complement(3144781..3146544) 1 NC_003143.1 hypothetical protein 3146544 1175639 YPO2814 Yersinia pestis CO92 hypothetical protein YP_002347754.1 3144781 R 214092 CDS YP_002347755.1 218929880 1175640 complement(3146541..3147173) 1 NC_003143.1 acyltransferase 3147173 1175640 YPO2815 Yersinia pestis CO92 acyltransferase YP_002347755.1 3146541 R 214092 CDS YP_002347756.1 218929881 1175641 complement(3147183..3148112) 1 NC_003143.1 phosphatidate cytidylyltransferase 3148112 ynbB 1175641 ynbB Yersinia pestis CO92 phosphatidate cytidylyltransferase YP_002347756.1 3147183 R 214092 CDS YP_002347757.1 218929882 1175642 complement(3148105..3148707) 1 NC_003143.1 CDP-alcohol phosphatidyltransferase 3148707 1175642 YPO2817 Yersinia pestis CO92 CDP-alcohol phosphatidyltransferase YP_002347757.1 3148105 R 214092 CDS YP_002347760.1 218929885 1175645 3149886..3150224 1 NC_003143.1 no significant database hits; hypothetical protein 3150224 1175645 YPO2820 Yersinia pestis CO92 hypothetical protein YP_002347760.1 3149886 D 214092 CDS YP_002347762.1 218929887 1175647 3150971..3151171 1 NC_003143.1 no significant database hits; hypothetical protein 3151171 1175647 YPO2822 Yersinia pestis CO92 hypothetical protein YP_002347762.1 3150971 D 214092 CDS YP_002347763.1 218929888 1175648 3151430..3151612 1 NC_003143.1 regulatory protein 3151612 1175648 YPO2823 Yersinia pestis CO92 regulatory protein YP_002347763.1 3151430 D 214092 CDS YP_002347764.1 218929889 1175650 3151967..3152833 1 NC_003143.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 3152833 folD 1175650 folD Yersinia pestis CO92 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002347764.1 3151967 D 214092 CDS YP_002347765.1 218929890 1175651 3152848..3153060 1 NC_003143.1 hypothetical protein 3153060 1175651 YPO2825 Yersinia pestis CO92 hypothetical protein YP_002347765.1 3152848 D 214092 CDS YP_002347766.1 218929891 1175652 complement(3153207..3153665) 1 NC_003143.1 transposase for the IS1541 insertion element 3153665 tnp 1175652 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347766.1 3153207 R 214092 CDS YP_002347767.1 218929892 1175653 complement(3153841..3154467) 1 NC_003143.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 3154467 upp 1175653 upp Yersinia pestis CO92 uracil phosphoribosyltransferase YP_002347767.1 3153841 R 214092 CDS YP_002347768.1 218929893 1175654 3154864..3155907 1 NC_003143.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 3155907 purI 1175654 purI Yersinia pestis CO92 phosphoribosylaminoimidazole synthetase YP_002347768.1 3154864 D 214092 CDS YP_002347769.1 218929894 1175655 3156022..3156660 1 NC_003143.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 3156660 purN 1175655 purN Yersinia pestis CO92 phosphoribosylglycinamide formyltransferase YP_002347769.1 3156022 D 214092 CDS YP_002347770.1 218929895 1175656 3156889..3157434 1 NC_003143.1 spermidine acetyltransferase 3157434 speG 1175656 speG Yersinia pestis CO92 spermidine acetyltransferase YP_002347770.1 3156889 D 214092 CDS YP_002347771.1 218929896 1175658 complement(3158945..3159757) 1 NC_003143.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 3159757 pstb 1175658 pstb Yersinia pestis CO92 phosphate transporter ATP-binding protein YP_002347771.1 3158945 R 214092 CDS YP_002347772.1 218929897 1175659 complement(3159785..3161497) 1 NC_003143.1 phosphate transporter permease 3161497 pstA 1175659 pstA Yersinia pestis CO92 phosphate transporter permease YP_002347772.1 3159785 R 214092 CDS YP_002347773.1 218929898 1175660 complement(3161497..3163746) 1 NC_003143.1 phosphate transporter permease 3163746 pstC 1175660 pstC Yersinia pestis CO92 phosphate transporter permease YP_002347773.1 3161497 R 214092 CDS YP_002347774.1 218929899 1175661 3163999..3166062 1 NC_003143.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 3166062 ppk 1175661 ppk Yersinia pestis CO92 polyphosphate kinase YP_002347774.1 3163999 D 214092 CDS YP_002347775.1 218929900 1175662 3166073..3167632 1 NC_003143.1 exopolyphosphatase 3167632 ppx 1175662 ppx Yersinia pestis CO92 exopolyphosphatase YP_002347775.1 3166073 D 214092 CDS YP_002347776.1 218929901 1175663 3167744..3167956 1 NC_003143.1 hypothetical protein 3167956 yfgG 1175663 yfgG Yersinia pestis CO92 hypothetical protein YP_002347776.1 3167744 D 214092 CDS YP_002347777.1 218929902 1175664 3168008..3169483 1 NC_003143.1 divalent cation transport protein 3169483 mgtE 1175664 mgtE Yersinia pestis CO92 divalent cation transport protein YP_002347777.1 3168008 D 214092 CDS YP_002347778.1 218929903 1175665 3169623..3170975 1 NC_003143.1 chaperone 3170975 1175665 YPO2840 Yersinia pestis CO92 chaperone YP_002347778.1 3169623 D 214092 CDS YP_002347779.1 218929904 1175666 complement(3171247..3172095) 1 NC_003143.1 ABC transporter permease 3172095 1175666 YPO2841 Yersinia pestis CO92 ABC transporter permease YP_002347779.1 3171247 R 214092 CDS YP_002347780.1 218929905 1175667 complement(3172157..3173422) 1 NC_003143.1 ABC transporter permease 3173422 1175667 YPO2842 Yersinia pestis CO92 ABC transporter permease YP_002347780.1 3172157 R 214092 CDS YP_002347781.1 218929906 1175668 complement(3173469..3174497) 1 NC_003143.1 transport system periplasmic protein 3174497 1175668 YPO2843 Yersinia pestis CO92 transport system periplasmic protein YP_002347781.1 3173469 R 214092 CDS YP_002347782.1 218929907 1175669 complement(3174550..3175863) 1 NC_003143.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 3175863 goaG 1175669 goaG Yersinia pestis CO92 4-aminobutyrate aminotransferase YP_002347782.1 3174550 R 214092 CDS YP_002347783.1 218929908 1175670 3176021..3177526 1 NC_003143.1 GntR family transcriptional regulator 3177526 1175670 YPO2845 Yersinia pestis CO92 GntR family transcriptional regulator YP_002347783.1 3176021 D 214092 CDS YP_002347784.1 218929909 1175671 3177909..3178994 1 NC_003143.1 ABC transporter ATP-binding protein 3178994 1175671 YPO2846 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002347784.1 3177909 D 214092 CDS YP_002347785.1 218929910 1175672 3179358..3180692 1 NC_003143.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 3180692 yegM 1175672 yegM Yersinia pestis CO92 multidrug efflux system subunit MdtA YP_002347785.1 3179358 D 214092 CDS YP_002347786.1 218929911 1175673 3180692..3183850 1 NC_003143.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 3183850 yegN 1175673 yegN Yersinia pestis CO92 multidrug efflux system subunit MdtB YP_002347786.1 3180692 D 214092 CDS YP_002347787.1 218929912 1175674 3183847..3186921 1 NC_003143.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 3186921 yegO 1175674 yegO Yersinia pestis CO92 multidrug efflux system subunit MdtC YP_002347787.1 3183847 D 214092 CDS YP_002347788.1 218929913 1175675 3186955..3188352 1 NC_003143.1 multidrug efflux system protein MdtE 3188352 yegB 1175675 yegB Yersinia pestis CO92 multidrug efflux system protein MdtE YP_002347788.1 3186955 D 214092 CDS YP_002347789.1 218929914 1175677 3189777..3190496 1 NC_003143.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 3190496 baeR 1175677 baeR Yersinia pestis CO92 DNA-binding transcriptional regulator BaeR YP_002347789.1 3189777 D 214092 CDS YP_002347790.1 218929915 1175678 3190633..3190971 1 NC_003143.1 hypothetical protein 3190971 1175678 YPO2854 Yersinia pestis CO92 hypothetical protein YP_002347790.1 3190633 D 214092 CDS YP_002347791.1 218929916 1175679 3191246..3192640 1 NC_003143.1 protease 3192640 1175679 YPO2855 Yersinia pestis CO92 protease YP_002347791.1 3191246 D 214092 CDS YP_002347792.1 218929917 1175680 3193276..3194166 1 NC_003143.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 3194166 1175680 YPO2856 Yersinia pestis CO92 lipid kinase YP_002347792.1 3193276 D 214092 CDS YP_002347793.1 218929918 1175681 complement(3194433..3194897) 1 NC_003143.1 hypothetical protein 3194897 1175681 YPO2857 Yersinia pestis CO92 hypothetical protein YP_002347793.1 3194433 R 214092 CDS YP_002347794.1 218929919 1175682 3195291..3196061 1 NC_003143.1 hypothetical protein 3196061 1175682 YPO2858 Yersinia pestis CO92 hypothetical protein YP_002347794.1 3195291 D 214092 CDS YP_002347795.1 218929920 1175683 complement(3196123..3196923) 1 NC_003143.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 3196923 thiD 1175683 thiD Yersinia pestis CO92 phosphomethylpyrimidine kinase YP_002347795.1 3196123 R 214092 CDS YP_002347796.1 218929921 1175684 3197433..3197912 1 NC_003143.1 No significant database matches. CDS DNA has a low GC content, 32.91%. Similar to YPO3895 (56.6% identity in 159 aa overlap), YPO3935 (55.7% identity in 158 aa overlap), YPO3894 (53.8% identity in 160 aa overlap). C-terminal region of the CDS is similar to YPO3893 (55.7% identity in 122 aa overlap); hypothetical protein 3197912 1175684 YPO2860 Yersinia pestis CO92 hypothetical protein YP_002347796.1 3197433 D 214092 CDS YP_002347797.1 218929922 1175686 complement(3198261..3199469) 1 NC_003143.1 transposase for the IS285 insertion element 3199469 y1062 1175686 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002347797.1 3198261 R 214092 CDS YP_002347798.1 218929923 1175687 3199551..3200195 1 NC_003143.1 hypothetical protein 3200195 1175687 YPO2863 Yersinia pestis CO92 hypothetical protein YP_002347798.1 3199551 D 214092 CDS YP_002347799.1 218929924 1175688 3200192..3200587 1 NC_003143.1 No significant database matches. CDS DNA has a low GC content, 27.02%. Similar to YPO2866 (65.6% identity in 131 aa overlap), YPO2867 (62.9% identity in 132 aa overlap) and YPO2865 (61.8% identity in 131 aa overlap); hypothetical protein 3200587 1175688 YPO2864 Yersinia pestis CO92 hypothetical protein YP_002347799.1 3200192 D 214092 CDS YP_002347800.1 218929925 1175689 3200651..3201046 1 NC_003143.1 hypothetical protein 3201046 1175689 YPO2865 Yersinia pestis CO92 hypothetical protein YP_002347800.1 3200651 D 214092 CDS YP_002347801.1 218929926 1175690 3201084..3201503 1 NC_003143.1 hypothetical protein 3201503 1175690 YPO2866 Yersinia pestis CO92 hypothetical protein YP_002347801.1 3201084 D 214092 CDS YP_002347802.1 218929927 1175691 3201567..3201965 1 NC_003143.1 hypothetical protein 3201965 1175691 YPO2867 Yersinia pestis CO92 hypothetical protein YP_002347802.1 3201567 D 214092 CDS YP_002347803.1 218929928 1175692 3201989..3202468 1 NC_003143.1 hypothetical protein 3202468 1175692 YPO2868 Yersinia pestis CO92 hypothetical protein YP_002347803.1 3201989 D 214092 CDS YP_002347804.1 218929929 1175693 complement(3202628..3203086) 1 NC_003143.1 transposase for the IS1541 insertion element 3203086 tnp 1175693 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347804.1 3202628 R 214092 CDS YP_002347805.1 218929930 1175694 complement(3203461..3205038) 1 NC_003143.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 3205038 guaA 1175694 guaA Yersinia pestis CO92 GMP synthase YP_002347805.1 3203461 R 214092 CDS YP_002347806.1 218929931 1175695 complement(3205218..3206681) 1 NC_003143.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 3206681 guaB 1175695 guaB Yersinia pestis CO92 inosine 5'-monophosphate dehydrogenase YP_002347806.1 3205218 R 214092 CDS YP_002347807.1 218929932 1175696 3206851..3208230 1 NC_003143.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 3208230 xseA 1175696 xseA Yersinia pestis CO92 exodeoxyribonuclease VII large subunit YP_002347807.1 3206851 D 214092 CDS YP_002347808.1 218929933 1175697 complement(3208363..3208587) 1 NC_003143.1 hypothetical protein 3208587 1175697 YPO2873 Yersinia pestis CO92 hypothetical protein YP_002347808.1 3208363 R 214092 CDS YP_002347809.1 218929934 1175698 complement(3208636..3209592) 1 NC_003143.1 hypothetical protein 3209592 1175698 YPO2874 Yersinia pestis CO92 hypothetical protein YP_002347809.1 3208636 R 214092 CDS YP_002347810.1 218929935 1175699 complement(3209939..3211426) 1 NC_003143.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 3211426 engA 1175699 engA Yersinia pestis CO92 GTP-binding protein EngA YP_002347810.1 3209939 R 214092 CDS YP_002347811.1 218929936 1175700 complement(3211574..3212755) 1 NC_003143.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 3212755 yfgL 1175700 yfgL Yersinia pestis CO92 outer membrane protein assembly complex subunit YfgL YP_002347811.1 3211574 R 214092 CDS YP_002347812.1 218929937 1175701 complement(3212767..3213402) 1 NC_003143.1 hypothetical protein 3213402 yfgM 1175701 yfgM Yersinia pestis CO92 hypothetical protein YP_002347812.1 3212767 R 214092 CDS YP_002347813.1 218929938 1175702 complement(3213416..3214690) 1 NC_003143.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 3214690 hisS 1175702 hisS Yersinia pestis CO92 histidyl-tRNA synthetase YP_002347813.1 3213416 R 214092 CDS YP_002347814.1 218929939 1175703 complement(3214899..3216026) 1 NC_003143.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 3216026 ispG 1175703 ispG Yersinia pestis CO92 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002347814.1 3214899 R 214092 CDS YP_002347815.1 218929940 1175704 complement(3216088..3217125) 1 NC_003143.1 cytoskeletal protein RodZ 3217125 yfgA 1175704 yfgA Yersinia pestis CO92 cytoskeletal protein RodZ YP_002347815.1 3216088 R 214092 CDS YP_002347816.1 218929941 1175705 complement(3217115..3217864) 1 NC_003143.1 fimbrial biogenesis protein 3217864 1175705 YPO2881 Yersinia pestis CO92 fimbrial biogenesis protein YP_002347816.1 3217115 R 214092 CDS YP_002347817.1 218929942 1175706 complement(3218018..3219214) 1 NC_003143.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 3219214 1175706 YPO2882 Yersinia pestis CO92 ribosomal RNA large subunit methyltransferase N YP_002347817.1 3218018 R 214092 CDS YP_002347818.1 218929943 1175707 complement(3219476..3219904) 1 NC_003143.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 3219904 ndk 1175707 ndk Yersinia pestis CO92 nucleoside diphosphate kinase YP_002347818.1 3219476 R 214092 CDS YP_002347819.1 218929944 1175708 complement(3220231..3222651) 1 NC_003143.1 hypothetical protein 3222651 1175708 YPO2884 Yersinia pestis CO92 hypothetical protein YP_002347819.1 3220231 R 214092 CDS YP_002347821.1 218929946 1175710 3223437..3227729 1 NC_003143.1 autotransporter protein 3227729 yapA 1175710 yapA Yersinia pestis CO92 autotransporter protein YP_002347821.1 3223437 D 214092 CDS YP_002347822.1 218929947 1175712 complement(3232069..3233022) 1 NC_003143.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 3233022 1175712 YPO2888 Yersinia pestis CO92 enhanced serine sensitivity protein SseB YP_002347822.1 3232069 R 214092 CDS YP_002347823.1 218929948 1175713 complement(3233101..3234399) 1 NC_003143.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase 3234399 pepB 1175713 pepB Yersinia pestis CO92 aminopeptidase YP_002347823.1 3233101 R 214092 CDS YP_002347824.1 218929949 1175714 complement(3234539..3234739) 1 NC_003143.1 hypothetical protein 3234739 1175714 YPO2890 Yersinia pestis CO92 hypothetical protein YP_002347824.1 3234539 R 214092 CDS YP_002347825.1 218929950 1175715 complement(3234769..3235104) 1 NC_003143.1 adrenodoxin family ferredoxin 3235104 fdx 1175715 fdx Yersinia pestis CO92 adrenodoxin family ferredoxin YP_002347825.1 3234769 R 214092 CDS YP_002347826.1 218929951 1175716 complement(3235107..3237059) 1 NC_003143.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 3237059 hscA 1175716 hscA Yersinia pestis CO92 chaperone protein HscA YP_002347826.1 3235107 R 214092 CDS YP_002347827.1 218929952 1175717 complement(3237302..3237826) 1 NC_003143.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 3237826 hscB 1175717 hscB Yersinia pestis CO92 co-chaperone HscB YP_002347827.1 3237302 R 214092 CDS YP_002347828.1 218929953 1175718 complement(3237937..3238260) 1 NC_003143.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 3238260 iscA 1175718 iscA Yersinia pestis CO92 iron-sulfur cluster assembly protein YP_002347828.1 3237937 R 214092 CDS YP_002347829.1 218929954 1175719 complement(3238530..3238916) 1 NC_003143.1 scaffold protein 3238916 nifU 1175719 nifU Yersinia pestis CO92 scaffold protein YP_002347829.1 3238530 R 214092 CDS YP_002347830.1 218929955 1175720 complement(3238947..3240176) 1 NC_003143.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 3240176 iscS 1175720 iscS Yersinia pestis CO92 cysteine desulfurase YP_002347830.1 3238947 R 214092 CDS YP_002347831.1 218929956 1175721 complement(3240230..3240724) 1 NC_003143.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 3240724 1175721 YPO2897 Yersinia pestis CO92 DNA-binding transcriptional regulator IscR YP_002347831.1 3240230 R 214092 CDS YP_002347832.1 218929957 1175722 complement(3240880..3241653) 1 NC_003143.1 SpoU family rRNA methylase 3241653 1175722 YPO2898 Yersinia pestis CO92 SpoU family rRNA methylase YP_002347832.1 3240880 R 214092 CDS YP_002347833.1 218929958 1175723 3241772..3242575 1 NC_003143.1 inositol monophosphatase 3242575 suhB 1175723 suhB Yersinia pestis CO92 inositol monophosphatase YP_002347833.1 3241772 D 214092 CDS YP_002347834.1 218929959 1175724 3242779..3243237 1 NC_003143.1 transposase for the IS1541 insertion element 3243237 tnp 1175724 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347834.1 3242779 D 214092 CDS YP_002347835.1 218929960 1175725 complement(3243384..3244406) 1 NC_003143.1 hypothetical protein 3244406 1175725 YPO2901 Yersinia pestis CO92 hypothetical protein YP_002347835.1 3243384 R 214092 CDS YP_002347836.1 218929961 1175726 complement(3244397..3245071) 1 NC_003143.1 hypothetical protein 3245071 1175726 YPO2902 Yersinia pestis CO92 hypothetical protein YP_002347836.1 3244397 R 214092 CDS YP_002347837.1 218929962 1175727 3245213..3246574 1 NC_003143.1 stationary phase inducible protein CsiE 3246574 1175727 YPO2903 Yersinia pestis CO92 stationary phase inducible protein CsiE YP_002347837.1 3245213 D 214092 CDS YP_002347838.1 218929963 1175728 complement(3246571..3247728) 1 NC_003143.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 3247728 hcaT 1175728 hcaT Yersinia pestis CO92 3-phenylpropionic acid transporter YP_002347838.1 3246571 R 214092 CDS YP_002347839.1 218929964 1175729 complement(3248080..3248628) 1 NC_003143.1 attachment invasion locus protein 3248628 ail 1175729 ail Yersinia pestis CO92 attachment invasion locus protein YP_002347839.1 3248080 R 214092 CDS YP_002347841.1 218929966 1175731 complement(3249072..3250325) 1 NC_003143.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 3250325 glyA 1175731 glyA Yersinia pestis CO92 serine hydroxymethyltransferase YP_002347841.1 3249072 R 214092 CDS YP_002347842.1 218929967 1175732 3250866..3252056 1 NC_003143.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 3252056 hmp 1175732 hmp Yersinia pestis CO92 nitric oxide dioxygenase YP_002347842.1 3250866 D 214092 CDS YP_002347843.1 218929968 1175734 complement(3253589..3253927) 1 NC_003143.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 3253927 glnB 1175734 glnB Yersinia pestis CO92 nitrogen regulatory protein P-II 1 YP_002347843.1 3253589 R 214092 CDS YP_002347844.1 218929969 1175735 complement(3253942..3255564) 1 NC_003143.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 3255564 nadE 1175735 nadE Yersinia pestis CO92 NAD synthetase YP_002347844.1 3253942 R 214092 CDS YP_002347845.1 218929970 1175736 complement(3255724..3257061) 1 NC_003143.1 two-component system response regulator 3257061 1175736 YPO2914 Yersinia pestis CO92 two-component system response regulator YP_002347845.1 3255724 R 214092 CDS YP_002347846.1 218929971 1175737 complement(3257024..3258019) 1 NC_003143.1 hypothetical protein 3258019 1175737 YPO2915 Yersinia pestis CO92 hypothetical protein YP_002347846.1 3257024 R 214092 CDS YP_002347847.1 218929972 1175738 complement(3258095..3259546) 1 NC_003143.1 two-component system sensor kinase 3259546 1175738 YPO2916 Yersinia pestis CO92 two-component system sensor kinase YP_002347847.1 3258095 R 214092 CDS YP_002347848.1 218929973 1175739 complement(3259752..3260210) 1 NC_003143.1 transposase for the IS1541 insertion element 3260210 tnp 1175739 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347848.1 3259752 R 214092 CDS YP_002347849.1 218929974 1175740 3261437..3261997 1 NC_003143.1 hypothetical protein 3261997 1175740 YPO2918 Yersinia pestis CO92 hypothetical protein YP_002347849.1 3261437 D 214092 CDS YP_002347851.1 218929976 1175742 complement(3263310..3267200) 1 NC_003143.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 3267200 purL 1175742 purL Yersinia pestis CO92 phosphoribosylformylglycinamidine synthase YP_002347851.1 3263310 R 214092 CDS YP_002347852.1 218929977 1175743 3267516..3268976 1 NC_003143.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 3268976 1175743 YPO2922 Yersinia pestis CO92 transglycosylase YP_002347852.1 3267516 D 214092 CDS YP_002347853.2 537470186 1175744 complement(3269085..3269687) 1 NC_003143.1 tRNA-specific adenosine deaminase 3269687 1175744 YPO2923 Yersinia pestis CO92 tRNA-specific adenosine deaminase YP_002347853.2 3269085 R 214092 CDS YP_002347854.1 218929979 1175745 complement(3269758..3270405) 1 NC_003143.1 hypothetical protein 3270405 yfhB 1175745 yfhB Yersinia pestis CO92 hypothetical protein YP_002347854.1 3269758 R 214092 CDS YP_002347855.1 218929980 1175746 complement(3270680..3271567) 1 NC_003143.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid-6-phosphate etherase 3271567 murQ 1175746 murQ Yersinia pestis CO92 N-acetylmuramic acid-6-phosphate etherase YP_002347855.1 3270680 R 214092 CDS YP_002347856.1 218929981 1175747 3271775..3272614 1 NC_003143.1 DNA-binding transcriptional regulator 3272614 1175747 YPO2926 Yersinia pestis CO92 DNA-binding transcriptional regulator YP_002347856.1 3271775 D 214092 CDS YP_002347857.1 218929982 1175748 3272776..3273036 1 NC_003143.1 [4Fe-4S] ferredoxin 3273036 fdx 1175748 fdx Yersinia pestis CO92 [4Fe-4S] ferredoxin YP_002347857.1 3272776 D 214092 CDS YP_002347858.1 218929983 1175749 complement(3273192..3273650) 1 NC_003143.1 transposase for the IS1541 insertion element 3273650 tnp 1175749 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347858.1 3273192 R 214092 CDS YP_002347859.1 218929984 1175750 complement(3273852..3274232) 1 NC_003143.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 3274232 acpS 1175750 acpS Yersinia pestis CO92 4'-phosphopantetheinyl transferase YP_002347859.1 3273852 R 214092 CDS YP_002347860.1 218929985 1175751 complement(3274232..3274963) 1 NC_003143.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 3274963 pdxJ 1175751 pdxJ Yersinia pestis CO92 pyridoxine 5'-phosphate synthase YP_002347860.1 3274232 R 214092 CDS YP_002347861.1 218929986 1175752 complement(3275153..3275935) 1 NC_003143.1 transposase/IS protein 3275935 1175752 YPO2931 Yersinia pestis CO92 transposase/IS protein YP_002347861.1 3275153 R 214092 CDS YP_002347862.1 218929987 1175753 complement(3275932..3276954) 1 NC_003143.1 transposase for insertion sequence IS100 3276954 y1093 1175753 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002347862.1 3275932 R 214092 CDS YP_002347863.1 218929988 1175755 complement(3277633..3278982) 1 NC_003143.1 hypothetical protein 3278982 1175755 YPO2934 Yersinia pestis CO92 hypothetical protein YP_002347863.1 3277633 R 214092 CDS YP_002347864.1 218929989 1175756 complement(3278986..3279546) 1 NC_003143.1 hypothetical protein 3279546 1175756 YPO2935 Yersinia pestis CO92 hypothetical protein YP_002347864.1 3278986 R 214092 CDS YP_002347865.1 218929990 1175757 complement(3279799..3280284) 1 NC_003143.1 hypothetical protein 3280284 1175757 YPO2937 Yersinia pestis CO92 hypothetical protein YP_002347865.1 3279799 R 214092 CDS YP_002347866.1 218929991 1175758 complement(3280610..3282112) 1 NC_003143.1 hypothetical protein 3282112 1175758 YPO2938 Yersinia pestis CO92 hypothetical protein YP_002347866.1 3280610 R 214092 CDS YP_002347867.1 218929992 1175759 complement(3282136..3282660) 1 NC_003143.1 hypothetical protein 3282660 1175759 YPO2939 Yersinia pestis CO92 hypothetical protein YP_002347867.1 3282136 R 214092 CDS YP_002347868.1 218929993 1175760 complement(3282765..3283319) 1 NC_003143.1 fimbrial protein 3283319 1175760 YPO2940 Yersinia pestis CO92 fimbrial protein YP_002347868.1 3282765 R 214092 CDS YP_002347869.1 218929994 1175762 3284573..3285781 1 NC_003143.1 transposase for the IS285 insertion element 3285781 y1062 1175762 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002347869.1 3284573 D 214092 CDS YP_002347870.1 218929995 1175763 complement(3287481..3288260) 1 NC_003143.1 pili chaperone protein 3288260 1175763 YPO2944 Yersinia pestis CO92 pili chaperone protein YP_002347870.1 3287481 R 214092 CDS YP_002347871.1 218929996 1175764 complement(3288399..3288944) 1 NC_003143.1 frimbrial protein 3288944 1175764 YPO2945 Yersinia pestis CO92 frimbrial protein YP_002347871.1 3288399 R 214092 CDS YP_002347872.1 218929997 1175765 complement(3289145..3291820) 1 NC_003143.1 Clp ATPase 3291820 clpB5 1175765 clpB5 Yersinia pestis CO92 Clp ATPase YP_002347872.1 3289145 R 214092 CDS YP_002347873.1 218929998 1175766 3292603..3294483 1 NC_003143.1 hypothetical protein 3294483 1175766 YPO2947 Yersinia pestis CO92 hypothetical protein YP_002347873.1 3292603 D 214092 CDS YP_002347874.1 218929999 1175767 3294483..3295508 1 NC_003143.1 hypothetical protein 3295508 1175767 YPO2948 Yersinia pestis CO92 hypothetical protein YP_002347874.1 3294483 D 214092 CDS YP_002347875.1 218930000 1175768 3295607..3296788 1 NC_003143.1 hypothetical protein 3296788 1175768 YPO2949 Yersinia pestis CO92 hypothetical protein YP_002347875.1 3295607 D 214092 CDS YP_002347876.1 218930001 1175769 3296795..3297826 1 NC_003143.1 fimbrial protein 3297826 1175769 YPO2950 Yersinia pestis CO92 fimbrial protein YP_002347876.1 3296795 D 214092 CDS YP_002347877.1 218930002 1175770 3297866..3299203 1 NC_003143.1 no significant database hits; hypothetical protein 3299203 1175770 YPO2951 Yersinia pestis CO92 hypothetical protein YP_002347877.1 3297866 D 214092 CDS YP_002347878.1 218930003 1175771 3299200..3299883 1 NC_003143.1 hypothetical protein 3299883 1175771 YPO2952 Yersinia pestis CO92 hypothetical protein YP_002347878.1 3299200 D 214092 CDS YP_002347879.1 218930004 1175772 3299884..3301566 1 NC_003143.1 hypothetical protein 3301566 1175772 YPO2953 Yersinia pestis CO92 hypothetical protein YP_002347879.1 3299884 D 214092 CDS YP_002347880.1 218930005 1175773 3301563..3302045 1 NC_003143.1 no significant database hits; hypothetical protein 3302045 1175773 YPO2954 Yersinia pestis CO92 hypothetical protein YP_002347880.1 3301563 D 214092 CDS YP_002347881.1 218930006 1175774 complement(3302403..3303005) 1 NC_003143.1 LuxR family transcriptional regulator 3303005 1175774 YPO2955 Yersinia pestis CO92 LuxR family transcriptional regulator YP_002347881.1 3302403 R 214092 CDS YP_002347882.1 218930007 1175775 complement(3304260..3305372) 1 NC_003143.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 3305372 mltB 1175775 mltB Yersinia pestis CO92 murein hydrolase B YP_002347882.1 3304260 R 214092 CDS YP_002347883.1 218930008 1175776 3305683..3306702 1 NC_003143.1 iron(III)-binding protein 3306702 sfuA 1175776 sfuA Yersinia pestis CO92 iron(III)-binding protein YP_002347883.1 3305683 D 214092 CDS YP_002347884.1 218930009 1175777 3306758..3308344 1 NC_003143.1 iron ABC transporter permease 3308344 sfuB 1175777 sfuB Yersinia pestis CO92 iron ABC transporter permease YP_002347884.1 3306758 D 214092 CDS YP_002347885.1 218930010 1175778 3308341..3309390 1 NC_003143.1 iron(III)-transport ATP-binding protein 3309390 sfuC 1175778 sfuC Yersinia pestis CO92 iron(III)-transport ATP-binding protein YP_002347885.1 3308341 D 214092 CDS YP_002347886.1 218930011 1175779 complement(3309463..3309987) 1 NC_003143.1 hypothetical protein 3309987 1175779 YPO2961 Yersinia pestis CO92 hypothetical protein YP_002347886.1 3309463 R 214092 CDS YP_002347887.1 218930012 1175780 3310448..3310933 1 NC_003143.1 hypothetical protein 3310933 1175780 YPO2962 Yersinia pestis CO92 hypothetical protein YP_002347887.1 3310448 D 214092 CDS YP_002347888.1 218930013 1175781 complement(3311163..3312011) 1 NC_003143.1 hypothetical protein 3312011 1175781 YPO2963 Yersinia pestis CO92 hypothetical protein YP_002347888.1 3311163 R 214092 CDS YP_002347889.1 218930014 1175782 3312842..3315268 1 NC_003143.1 dimethyl sulfoxide reductase subunit A 3315268 dmsA 1175782 dmsA Yersinia pestis CO92 dimethyl sulfoxide reductase subunit A YP_002347889.1 3312842 D 214092 CDS YP_002347890.1 218930015 1175783 3315280..3315897 1 NC_003143.1 dimethyl sulfoxide reductase subunit B 3315897 dmsB 1175783 dmsB Yersinia pestis CO92 dimethyl sulfoxide reductase subunit B YP_002347890.1 3315280 D 214092 CDS YP_002347891.1 218930016 1175784 3315899..3316675 1 NC_003143.1 dimethyl sulfoxide reductase subunit C 3316675 dmsC 1175784 dmsC Yersinia pestis CO92 dimethyl sulfoxide reductase subunit C YP_002347891.1 3315899 D 214092 CDS YP_002347892.1 218930017 1175785 3317088..3317753 1 NC_003143.1 hypothetical protein 3317753 1175785 YPO2968 Yersinia pestis CO92 hypothetical protein YP_002347892.1 3317088 D 214092 CDS YP_002347893.1 218930018 1175786 3317750..3318319 1 NC_003143.1 (Fe-S)-binding protein 3318319 1175786 YPO2969 Yersinia pestis CO92 (Fe-S)-binding protein YP_002347893.1 3317750 D 214092 CDS YP_002347894.1 218930019 1175787 complement(3318565..3319221) 1 NC_003143.1 lipoprotein 3319221 1175787 YPO2970 Yersinia pestis CO92 lipoprotein YP_002347894.1 3318565 R 214092 CDS YP_002347895.1 218930020 1175788 complement(3319218..3319574) 1 NC_003143.1 lipoprotein 3319574 1175788 YPO2971 Yersinia pestis CO92 lipoprotein YP_002347895.1 3319218 R 214092 CDS YP_002347896.1 218930021 1175789 complement(3319601..3320272) 1 NC_003143.1 lipoprotein 3320272 1175789 YPO2972 Yersinia pestis CO92 lipoprotein YP_002347896.1 3319601 R 214092 CDS YP_002347897.1 218930022 1175790 3320862..3321293 1 NC_003143.1 hypothetical protein 3321293 1175790 YPO2973 Yersinia pestis CO92 hypothetical protein YP_002347897.1 3320862 D 214092 CDS YP_002347898.1 218930023 1175791 complement(3321388..3321912) 1 NC_003143.1 B-type cytochrome 3321912 1175791 YPO2974 Yersinia pestis CO92 B-type cytochrome YP_002347898.1 3321388 R 214092 CDS YP_002347899.1 218930024 1175792 complement(3322157..3323392) 1 NC_003143.1 aminotransferase 3323392 1175792 YPO2975 Yersinia pestis CO92 aminotransferase YP_002347899.1 3322157 R 214092 CDS YP_002347900.1 218930025 1175793 3323658..3324905 1 NC_003143.1 hypothetical protein 3324905 1175793 YPO2976 Yersinia pestis CO92 hypothetical protein YP_002347900.1 3323658 D 214092 CDS YP_002347901.1 218930026 1175794 complement(3324983..3325954) 1 NC_003143.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 3325954 glk 1175794 glk Yersinia pestis CO92 glucokinase YP_002347901.1 3324983 R 214092 CDS YP_002347902.1 218930027 1175795 complement(3326135..3326662) 1 NC_003143.1 hypothetical protein 3326662 1175795 YPO2978 Yersinia pestis CO92 hypothetical protein YP_002347902.1 3326135 R 214092 CDS YP_002347903.1 218930028 1175796 3326714..3327592 1 NC_003143.1 LysR family transcriptional regulator 3327592 1175796 YPO2979 Yersinia pestis CO92 LysR family transcriptional regulator YP_002347903.1 3326714 D 214092 CDS YP_002347904.1 218930029 1175797 3327728..3328717 1 NC_003143.1 ion channel protein 3328717 1175797 YPO2980 Yersinia pestis CO92 ion channel protein YP_002347904.1 3327728 D 214092 CDS YP_002347905.1 218930030 1175798 3328888..3329301 1 NC_003143.1 hypothetical protein 3329301 1175798 YPO2981 Yersinia pestis CO92 hypothetical protein YP_002347905.1 3328888 D 214092 CDS YP_002347906.1 218930031 1175799 complement(3329394..3330623) 1 NC_003143.1 manganese transport protein MntH 3330623 mntH 1175799 mntH Yersinia pestis CO92 manganese transport protein MntH YP_002347906.1 3329394 R 214092 CDS YP_002347907.1 218930032 1175800 3331058..3332242 1 NC_003143.1 nucleoside permease 3332242 cru 1175800 cru Yersinia pestis CO92 nucleoside permease YP_002347907.1 3331058 D 214092 CDS YP_002347908.1 218930033 1175805 3333476..3334891 1 NC_003143.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 3334891 gltX 1175805 gltX Yersinia pestis CO92 glutamyl-tRNA synthetase YP_002347908.1 3333476 D 214092 CDS YP_002347909.1 218930034 1175806 3335084..3335542 1 NC_003143.1 transposase for the IS1541 insertion element 3335542 tnp 1175806 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347909.1 3335084 D 214092 CDS YP_002347910.1 218930035 1175809 3336256..3336861 1 NC_003143.1 hypothetical protein 3336861 1175809 YPO2986 Yersinia pestis CO92 hypothetical protein YP_002347910.1 3336256 D 214092 CDS YP_002347911.1 218930036 1175810 3336993..3337340 1 NC_003143.1 hypothetical protein 3337340 1175810 YPO2987 Yersinia pestis CO92 hypothetical protein YP_002347911.1 3336993 D 214092 CDS YP_002347912.1 218930037 1175811 complement(3337441..3337656) 1 NC_003143.1 hypothetical protein 3337656 1175811 YPO2988 Yersinia pestis CO92 hypothetical protein YP_002347912.1 3337441 R 214092 CDS YP_002347913.1 218930038 1175812 complement(3337676..3339688) 1 NC_003143.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 3339688 ligA 1175812 ligA Yersinia pestis CO92 NAD-dependent DNA ligase LigA YP_002347913.1 3337676 R 214092 CDS YP_002347914.1 218930039 1175813 complement(3339779..3340765) 1 NC_003143.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 3340765 zipA 1175813 zipA Yersinia pestis CO92 cell division protein ZipA YP_002347914.1 3339779 R 214092 CDS YP_002347915.1 218930040 1175814 3341014..3341748 1 NC_003143.1 role in sulfur assimilation; sulfate transport protein CysZ 3341748 cysZ 1175814 cysZ Yersinia pestis CO92 sulfate transport protein CysZ YP_002347915.1 3341014 D 214092 CDS YP_002347916.1 218930041 1175815 3341905..3342873 1 NC_003143.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 3342873 cysK 1175815 cysK Yersinia pestis CO92 cysteine synthase A YP_002347916.1 3341905 D 214092 CDS YP_002347917.1 218930042 1175816 3343372..3343629 1 NC_003143.1 PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr 3343629 ptsH 1175816 ptsH Yersinia pestis CO92 PTS system phosphohistidinoprotein-hexose phosphotransferase subunit Hpr YP_002347917.1 3343372 D 214092 CDS YP_002347918.1 218930043 1175817 3343678..3345405 1 NC_003143.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 3345405 ptsI 1175817 ptsI Yersinia pestis CO92 phosphoenolpyruvate-protein phosphotransferase YP_002347918.1 3343678 D 214092 CDS YP_002347919.1 218930044 1175818 3345454..3345963 1 NC_003143.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter subunit 3345963 crr 1175818 crr Yersinia pestis CO92 PTS system glucose-specific transporter subunit YP_002347919.1 3345454 D 214092 CDS YP_002347920.1 218930045 1175819 complement(3346106..3346564) 1 NC_003143.1 transposase for the IS1541 insertion element 3346564 tnp 1175819 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347920.1 3346106 R 214092 CDS YP_002347921.1 218930046 1175820 complement(3346834..3348183) 1 NC_003143.1 two-component system sensor kinase 3348183 1175820 YPO2997 Yersinia pestis CO92 two-component system sensor kinase YP_002347921.1 3346834 R 214092 CDS YP_002347922.1 218930047 1175821 complement(3348209..3348892) 1 NC_003143.1 two-component system response regulator 3348892 1175821 YPO2998 Yersinia pestis CO92 two-component system response regulator YP_002347922.1 3348209 R 214092 CDS YP_002347923.1 218930048 1175822 3349080..3350285 1 NC_003143.1 HlyD family secretion protein 3350285 1175822 YPO2999 Yersinia pestis CO92 HlyD family secretion protein YP_002347923.1 3349080 D 214092 CDS YP_002347924.1 218930049 1175823 3350289..3352325 1 NC_003143.1 ABC transporter ATP-binding protein 3352325 1175823 YPO3000 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002347924.1 3350289 D 214092 CDS YP_002347925.1 218930050 1175824 complement(3352580..3354226) 1 NC_003143.1 pyridine nucleotide-disulphide oxidoreductase 3354226 1175824 YPO3001 Yersinia pestis CO92 pyridine nucleotide-disulphide oxidoreductase YP_002347925.1 3352580 R 214092 CDS YP_002347926.1 218930051 1175825 complement(3354286..3355746) 1 NC_003143.1 permease 3355746 1175825 YPO3002 Yersinia pestis CO92 permease YP_002347926.1 3354286 R 214092 CDS YP_002347927.1 218930052 1175826 complement(3355743..3355940) 1 NC_003143.1 hypothetical protein 3355940 1175826 YPO3003 Yersinia pestis CO92 hypothetical protein YP_002347927.1 3355743 R 214092 CDS YP_008853947.1 559797722 1175827 complement(3356083..3357054) 1 NC_003143.1 hypothetical protein 3357054 1175827 YPO3004 Yersinia pestis CO92 hypothetical protein YP_008853947.1 3356083 R 214092 CDS YP_002347928.1 218930053 1175828 complement(3357336..3358517) 1 NC_003143.1 aminotransferase 3358517 1175828 YPO3006 Yersinia pestis CO92 aminotransferase YP_002347928.1 3357336 R 214092 CDS YP_002347929.1 218930054 1175829 3359114..3360643 1 NC_003143.1 hypothetical protein 3360643 1175829 YPO3007 Yersinia pestis CO92 hypothetical protein YP_002347929.1 3359114 D 214092 CDS YP_002347930.1 218930055 1175830 3360876..3362420 1 NC_003143.1 two-component sensor histidine kinase 3362420 1175830 YPO3008 Yersinia pestis CO92 two-component sensor histidine kinase YP_002347930.1 3360876 D 214092 CDS YP_002347931.1 218930056 1175831 3362417..3363124 1 NC_003143.1 two-component response regulator 3363124 1175831 YPO3009 Yersinia pestis CO92 two-component response regulator YP_002347931.1 3362417 D 214092 CDS YP_002347932.1 218930057 1175832 complement(3363505..3364737) 1 NC_003143.1 hypothetical protein 3364737 1175832 YPO3010 Yersinia pestis CO92 hypothetical protein YP_002347932.1 3363505 R 214092 CDS YP_002347933.1 218930058 1175833 complement(3364982..3365860) 1 NC_003143.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 3365860 cysM 1175833 cysM Yersinia pestis CO92 cysteine synthase B YP_002347933.1 3364982 R 214092 CDS YP_002347934.1 218930059 1175834 complement(3366031..3367122) 1 NC_003143.1 sulfate/thiosulfate transporter subunit 3367122 cysA 1175834 cysA Yersinia pestis CO92 sulfate/thiosulfate transporter subunit YP_002347934.1 3366031 R 214092 CDS YP_002347935.1 218930060 1175835 complement(3367112..3367987) 1 NC_003143.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease 3367987 cysW 1175835 cysW Yersinia pestis CO92 sulfate/thiosulfate transporter permease YP_002347935.1 3367112 R 214092 CDS YP_002347936.1 218930061 1175836 complement(3367987..3368820) 1 NC_003143.1 sulfate/thiosulfate transporter subunit 3368820 cysT 1175836 cysT Yersinia pestis CO92 sulfate/thiosulfate transporter subunit YP_002347936.1 3367987 R 214092 CDS YP_002347937.1 218930062 1175837 complement(3368820..3369857) 1 NC_003143.1 thiosulfate transporter subunit 3369857 cysP 1175837 cysP Yersinia pestis CO92 thiosulfate transporter subunit YP_002347937.1 3368820 R 214092 CDS YP_002347938.1 218930063 1175838 complement(3370172..3371704) 1 NC_003143.1 sialic acid transporter 3371704 nanT 1175838 nanT Yersinia pestis CO92 sialic acid transporter YP_002347938.1 3370172 R 214092 CDS YP_002347939.1 218930064 1175839 complement(3372309..3373187) 1 NC_003143.1 rpiR family transcriptional regulator 3373187 1175839 YPO3017 Yersinia pestis CO92 rpiR family transcriptional regulator YP_002347939.1 3372309 R 214092 CDS YP_002347940.1 218930065 1175840 complement(3373184..3373336) 1 NC_003143.1 doubtful CDS with no significant database matches. Very low %G+C; hypothetical protein 3373336 1175840 YPO3018 Yersinia pestis CO92 hypothetical protein YP_002347940.1 3373184 R 214092 CDS YP_002347941.1 218930066 1175841 complement(3373376..3373831) 1 NC_003143.1 hypothetical protein 3373831 1175841 YPO3019 Yersinia pestis CO92 hypothetical protein YP_002347941.1 3373376 R 214092 CDS YP_002347942.1 218930067 1175842 complement(3373928..3374800) 1 NC_003143.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3374800 1175842 YPO3020 Yersinia pestis CO92 N-acetylmannosamine kinase YP_002347942.1 3373928 R 214092 CDS YP_002347943.1 218930068 1175844 3376403..3377104 1 NC_003143.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 3377104 1175844 YPO3023 Yersinia pestis CO92 N-acetylmannosamine-6-phosphate 2-epimerase YP_002347943.1 3376403 D 214092 CDS YP_002347944.1 218930069 1175845 3377167..3378060 1 NC_003143.1 N-acetylneuraminate lyase 3378060 nanA 1175845 nanA Yersinia pestis CO92 N-acetylneuraminate lyase YP_002347944.1 3377167 D 214092 CDS YP_002347945.1 218930070 1175846 complement(3378158..3379057) 1 NC_003143.1 hypothetical protein 3379057 1175846 YPO3025 Yersinia pestis CO92 hypothetical protein YP_002347945.1 3378158 R 214092 CDS YP_002347946.1 218930071 1175847 complement(3379235..3379846) 1 NC_003143.1 hypothetical protein 3379846 yfeY 1175847 yfeY Yersinia pestis CO92 hypothetical protein YP_002347946.1 3379235 R 214092 CDS YP_002347947.1 218930072 1175848 3380205..3380618 1 NC_003143.1 hypothetical protein 3380618 ygiW 1175848 ygiW Yersinia pestis CO92 hypothetical protein YP_002347947.1 3380205 D 214092 CDS YP_002347948.1 218930073 1175849 3381105..3383384 1 NC_003143.1 autotransporter 3383384 1175849 YPO3028 Yersinia pestis CO92 autotransporter YP_002347948.1 3381105 D 214092 CDS YP_002347949.1 218930074 1175850 complement(3383476..3383892) 1 NC_003143.1 hypothetical protein 3383892 1175850 YPO3029 Yersinia pestis CO92 hypothetical protein YP_002347949.1 3383476 R 214092 CDS YP_002347950.1 218930075 1175851 3383998..3384183 1 NC_003143.1 no significant database hits; hypothetical protein 3384183 1175851 YPO3030 Yersinia pestis CO92 hypothetical protein YP_002347950.1 3383998 D 214092 CDS YP_002347951.1 218930076 1175852 complement(3384365..3384790) 1 NC_003143.1 acetyltransferase 3384790 1175852 YPO3031 Yersinia pestis CO92 acetyltransferase YP_002347951.1 3384365 R 214092 CDS YP_002347952.1 218930077 1175853 3385073..3386002 1 NC_003143.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 3386002 hemF 1175853 hemF Yersinia pestis CO92 coproporphyrinogen III oxidase YP_002347952.1 3385073 D 214092 CDS YP_002347953.1 218930078 1175854 3386002..3386460 1 NC_003143.1 hypothetical protein 3386460 1175854 YPO3033 Yersinia pestis CO92 hypothetical protein YP_002347953.1 3386002 D 214092 CDS YP_002347954.1 218930079 1175855 complement(3386611..3388896) 1 NC_003143.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 3388896 maeB 1175855 maeB Yersinia pestis CO92 malic enzyme YP_002347954.1 3386611 R 214092 CDS YP_002347955.1 218930080 1175856 complement(3389092..3389688) 1 NC_003143.1 hypothetical protein 3389688 1175856 YPO3035 Yersinia pestis CO92 hypothetical protein YP_002347955.1 3389092 R 214092 CDS YP_002347956.1 218930081 1175857 complement(3389872..3390474) 1 NC_003143.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 3390474 napC 1175857 napC Yersinia pestis CO92 cytochrome c-type protein NapC YP_002347956.1 3389872 R 214092 CDS YP_002347957.1 218930082 1175858 complement(3390499..3390966) 1 NC_003143.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 3390966 napB 1175858 napB Yersinia pestis CO92 citrate reductase cytochrome c-type subunit YP_002347957.1 3390499 R 214092 CDS YP_002347958.1 218930083 1175859 complement(3391049..3393541) 1 NC_003143.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 3393541 napA 1175859 napA Yersinia pestis CO92 nitrate reductase catalytic subunit YP_002347958.1 3391049 R 214092 CDS YP_002347959.1 218930084 1175860 complement(3393538..3393804) 1 NC_003143.1 assembly protein for periplasmic nitrate reductase 3393804 napD 1175860 napD Yersinia pestis CO92 assembly protein for periplasmic nitrate reductase YP_002347959.1 3393538 R 214092 CDS YP_002347960.1 218930085 1175861 complement(3393794..3394297) 1 NC_003143.1 ferredoxin-type protein NapF 3394297 napF 1175861 napF Yersinia pestis CO92 ferredoxin-type protein NapF YP_002347960.1 3393794 R 214092 CDS YP_002347961.1 218930086 1175862 3395130..3395759 1 NC_003143.1 nitrate/nitrite response regulator protein NarP 3395759 narP 1175862 narP Yersinia pestis CO92 nitrate/nitrite response regulator protein NarP YP_002347961.1 3395130 D 214092 CDS YP_002347962.1 218930087 1175863 complement(3395772..3396050) 1 NC_003143.1 hypothetical protein 3396050 1175863 YPO3042 Yersinia pestis CO92 hypothetical protein YP_002347962.1 3395772 R 214092 CDS YP_002347963.1 218930088 1175864 3396465..3399596 1 NC_003143.1 aminoglycoside/multidrug efflux system 3399596 1175864 YPO3043 Yersinia pestis CO92 aminoglycoside/multidrug efflux system YP_002347963.1 3396465 D 214092 CDS YP_002347964.1 218930089 1175865 3399827..3400411 1 NC_003143.1 hypothetical protein 3400411 1175865 YPO3044 Yersinia pestis CO92 hypothetical protein YP_002347964.1 3399827 D 214092 CDS YP_002347965.1 218930090 1175866 3400700..3401248 1 NC_003143.1 hypothetical protein 3401248 ybcI 1175866 ybcI Yersinia pestis CO92 hypothetical protein YP_002347965.1 3400700 D 214092 CDS YP_002347966.1 218930091 1175867 complement(3402002..3403177) 1 NC_003143.1 sulfatase modifier protein 3403177 1175867 YPO3046 Yersinia pestis CO92 sulfatase modifier protein YP_002347966.1 3402002 R 214092 CDS YP_002347967.1 218930092 1175868 complement(3403235..3404908) 1 NC_003143.1 sulfatase 3404908 ydeN 1175868 ydeN Yersinia pestis CO92 sulfatase YP_002347967.1 3403235 R 214092 CDS YP_002347968.1 218930093 1175869 complement(3405386..3406456) 1 NC_003143.1 ABC transporter ATP-binding protein 3406456 1175869 YPO3048 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002347968.1 3405386 R 214092 CDS YP_002347969.1 218930094 1175870 complement(3406449..3408218) 1 NC_003143.1 binding protein-dependent transporter inner membrane protein 3408218 1175870 YPO3049 Yersinia pestis CO92 binding protein-dependent transporter inner membrane protein YP_002347969.1 3406449 R 214092 CDS YP_002347970.1 218930095 1175871 complement(3408313..3409401) 1 NC_003143.1 hypothetical protein 3409401 1175871 YPO3050 Yersinia pestis CO92 hypothetical protein YP_002347970.1 3408313 R 214092 CDS YP_002347971.1 218930096 1175872 3409685..3410185 1 NC_003143.1 hypothetical protein 3410185 1175872 YPO3051 Yersinia pestis CO92 hypothetical protein YP_002347971.1 3409685 D 214092 CDS YP_002347972.1 218930097 1175873 3410345..3410743 1 NC_003143.1 hypothetical protein 3410743 1175873 YPO3052 Yersinia pestis CO92 hypothetical protein YP_002347972.1 3410345 D 214092 CDS YP_002347973.1 218930098 1175874 3410745..3411872 1 NC_003143.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 3411872 dapE 1175874 dapE Yersinia pestis CO92 succinyl-diaminopimelate desuccinylase YP_002347973.1 3410745 D 214092 CDS YP_002347974.1 218930099 1175875 3411869..3412546 1 NC_003143.1 carboxypeptidase 3412546 1175875 YPO3054 Yersinia pestis CO92 carboxypeptidase YP_002347974.1 3411869 D 214092 CDS YP_002347975.1 218930100 1175876 3412614..3412808 1 NC_003143.1 hypothetical protein 3412808 1175876 YPO3055 Yersinia pestis CO92 hypothetical protein YP_002347975.1 3412614 D 214092 CDS YP_002347976.1 218930101 1175877 complement(3413013..3415112) 1 NC_003143.1 acetyltransferase 3415112 1175877 YPO3056 Yersinia pestis CO92 acetyltransferase YP_002347976.1 3413013 R 214092 CDS YP_002347977.1 218930102 1175878 complement(3415114..3415566) 1 NC_003143.1 hypothetical protein 3415566 yeaL 1175878 yeaL Yersinia pestis CO92 hypothetical protein YP_002347977.1 3415114 R 214092 CDS YP_002347978.1 218930103 1175879 complement(3415660..3416526) 1 NC_003143.1 hypothetical protein 3416526 1175879 YPO3058 Yersinia pestis CO92 hypothetical protein YP_002347978.1 3415660 R 214092 CDS YP_002347979.1 218930104 1175880 complement(3416745..3417458) 1 NC_003143.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 3417458 purC 1175880 purC Yersinia pestis CO92 phosphoribosylaminoimidazole-succinocarboxamide synthase YP_002347979.1 3416745 R 214092 CDS YP_002347980.1 218930105 1175881 complement(3417606..3418064) 1 NC_003143.1 transposase for the IS1541 insertion element 3418064 tnp 1175881 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347980.1 3417606 R 214092 CDS YP_002347981.1 218930106 1175882 complement(3418239..3419297) 1 NC_003143.1 lipoprotein 3419297 dapX 1175882 dapX Yersinia pestis CO92 lipoprotein YP_002347981.1 3418239 R 214092 CDS YP_002347982.1 218930107 1175883 complement(3419315..3420196) 1 NC_003143.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 3420196 dapA 1175883 dapA Yersinia pestis CO92 dihydrodipicolinate synthase YP_002347982.1 3419315 R 214092 CDS YP_002347983.1 218930108 1175884 3420361..3420930 1 NC_003143.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 3420930 gcvR 1175884 gcvR Yersinia pestis CO92 glycine cleavage system transcriptional repressor YP_002347983.1 3420361 D 214092 CDS YP_002347984.1 218930109 1175885 3420930..3421403 1 NC_003143.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 3421403 bcp 1175885 bcp Yersinia pestis CO92 thioredoxin-dependent thiol peroxidase YP_002347984.1 3420930 D 214092 CDS YP_002347985.1 218930110 1175886 complement(3421647..3422066) 1 NC_003143.1 no significant database matches; hypothetical protein 3422066 1175886 YPO3065 Yersinia pestis CO92 hypothetical protein YP_002347985.1 3421647 R 214092 CDS YP_002347986.1 218930111 1175887 complement(3422070..3422765) 1 NC_003143.1 no significant database hits. Similar to YPO1619 (53% identity in 166 aa overlap); hypothetical protein 3422765 1175887 YPO3066 Yersinia pestis CO92 hypothetical protein YP_002347986.1 3422070 R 214092 CDS YP_002347987.1 218930112 1175888 3423103..3423276 1 NC_003143.1 no significant database hits; hypothetical protein 3423276 1175888 YPO3067 Yersinia pestis CO92 hypothetical protein YP_002347987.1 3423103 D 214092 CDS YP_002347988.1 218930113 1175889 complement(3423365..3424429) 1 NC_003143.1 hypothetical protein 3424429 perM 1175889 perM Yersinia pestis CO92 hypothetical protein YP_002347988.1 3423365 R 214092 CDS YP_002347989.1 218930114 1175890 3424784..3426244 1 NC_003143.1 hypothetical protein 3426244 1175890 YPO3069 Yersinia pestis CO92 hypothetical protein YP_002347989.1 3424784 D 214092 CDS YP_002347990.1 218930115 1175891 3426351..3426707 1 NC_003143.1 arsenate reductase 3426707 yfgD 1175891 yfgD Yersinia pestis CO92 arsenate reductase YP_002347990.1 3426351 D 214092 CDS YP_002347991.1 218930116 1175892 complement(3426919..3427638) 1 NC_003143.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 3427638 1175892 YPO3071 Yersinia pestis CO92 DNA replication initiation factor YP_002347991.1 3426919 R 214092 CDS YP_002347992.1 218930117 1175893 complement(3427814..3428272) 1 NC_003143.1 transposase for the IS1541 insertion element 3428272 tnp 1175893 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002347992.1 3427814 R 214092 CDS YP_002347993.1 218930118 1175894 complement(3428619..3430004) 1 NC_003143.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 3430004 cysS 1175894 cysS Yersinia pestis CO92 cysteinyl-tRNA synthetase YP_002347993.1 3428619 R 214092 CDS YP_002347994.1 218930119 1175895 3430215..3430709 1 NC_003143.1 peptidyl-prolyl cis-trans isomerase B 3430709 ppiB 1175895 ppiB Yersinia pestis CO92 peptidyl-prolyl cis-trans isomerase B YP_002347994.1 3430215 D 214092 CDS YP_002347995.1 218930120 1175896 3430720..3431442 1 NC_003143.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 3431442 1175896 YPO3075 Yersinia pestis CO92 UDP-2,3-diacylglucosamine hydrolase YP_002347995.1 3430720 D 214092 CDS YP_002347996.1 218930121 1175897 3431738..3432262 1 NC_003143.1 phosphoribosylaminoimidazole carboxylase catalytic subunit PurE 3432262 purE 1175897 purE Yersinia pestis CO92 phosphoribosylaminoimidazole carboxylase catalytic subunit PurE YP_002347996.1 3431738 D 214092 CDS YP_002347997.1 218930122 1175898 3432259..3433323 1 NC_003143.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 3433323 purK 1175898 purK Yersinia pestis CO92 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_002347997.1 3432259 D 214092 CDS YP_002347998.1 218930123 1175899 complement(3433367..3435796) 1 NC_003143.1 permease 3435796 ybbP 1175899 ybbP Yersinia pestis CO92 permease YP_002347998.1 3433367 R 214092 CDS YP_002347999.1 218930124 1175900 complement(3435793..3436479) 1 NC_003143.1 ABC transporter ATP-binding protein YbbA 3436479 ybbA 1175900 ybbA Yersinia pestis CO92 ABC transporter ATP-binding protein YbbA YP_002347999.1 3435793 R 214092 CDS YP_002348000.1 218930125 1175901 3436447..3437085 1 NC_003143.1 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 3437085 tesA 1175901 tesA Yersinia pestis CO92 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 YP_002348000.1 3436447 D 214092 CDS YP_002348001.1 218930126 1175902 3437472..3438248 1 NC_003143.1 short chain dehydrogenase 3438248 ybbO 1175902 ybbO Yersinia pestis CO92 short chain dehydrogenase YP_002348001.1 3437472 D 214092 CDS YP_002348002.1 218930127 1175903 3438325..3439194 1 NC_003143.1 thioredoxin 3439194 ybbN 1175903 ybbN Yersinia pestis CO92 thioredoxin YP_002348002.1 3438325 D 214092 CDS YP_002348003.1 218930128 1175904 3439389..3440303 1 NC_003143.1 hypothetical protein 3440303 1175904 YPO3083 Yersinia pestis CO92 hypothetical protein YP_002348003.1 3439389 D 214092 CDS YP_002348004.1 218930129 1175905 3440306..3440755 1 NC_003143.1 hypothetical protein 3440755 ybbJ 1175905 ybbJ Yersinia pestis CO92 hypothetical protein YP_002348004.1 3440306 D 214092 CDS YP_002348005.1 218930130 1175906 complement(3440864..3441283) 1 NC_003143.1 regulatory protein 3441283 cueR 1175906 cueR Yersinia pestis CO92 regulatory protein YP_002348005.1 3440864 R 214092 CDS YP_002348006.1 218930131 1175907 3441490..3444375 1 NC_003143.1 copper exporting ATPase 3444375 copA 1175907 copA Yersinia pestis CO92 copper exporting ATPase YP_002348006.1 3441490 D 214092 CDS YP_002348007.1 218930132 1175908 3444896..3445705 1 NC_003143.1 hypothetical protein 3445705 1175908 YPO3087 Yersinia pestis CO92 hypothetical protein YP_002348007.1 3444896 D 214092 CDS YP_002348008.1 218930133 1175909 3445969..3446448 1 NC_003143.1 hypothetical protein 3446448 1175909 YPO3088 Yersinia pestis CO92 hypothetical protein YP_002348008.1 3445969 D 214092 CDS YP_002348009.1 218930134 1175910 3446740..3447024 1 NC_003143.1 no significant database hits; hypothetical protein 3447024 1175910 YPO3089 Yersinia pestis CO92 hypothetical protein YP_002348009.1 3446740 D 214092 CDS YP_002348010.1 218930135 1175912 3449065..3450279 1 NC_003143.1 membrane efflux protein 3450279 fsr 1175912 fsr Yersinia pestis CO92 membrane efflux protein YP_002348010.1 3449065 D 214092 CDS YP_002348011.1 218930136 1175913 3450514..3452205 1 NC_003143.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein 3452205 rosB 1175913 rosB Yersinia pestis CO92 cation:proton antiport protein YP_002348011.1 3450514 D 214092 CDS YP_002348012.1 218930137 1175914 complement(3452302..3453606) 1 NC_003143.1 inosine-guanosine kinase 3453606 gsk 1175914 gsk Yersinia pestis CO92 inosine-guanosine kinase YP_002348012.1 3452302 R 214092 CDS YP_002348013.1 218930138 1175915 complement(3453810..3454961) 1 NC_003143.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 3454961 wzz 1175915 wzz Yersinia pestis CO92 ferric enterobactin transport protein FepE YP_002348013.1 3453810 R 214092 CDS YP_002348014.1 218930139 1175916 complement(3455009..3456382) 1 NC_003143.1 phosphomannomutase 3456382 manB 1175916 manB Yersinia pestis CO92 phosphomannomutase YP_002348014.1 3455009 R 214092 CDS YP_002348015.1 218930140 1175917 complement(3456387..3457130) 1 NC_003143.1 glycosyltransferase 3457130 wbyL 1175917 wbyL Yersinia pestis CO92 glycosyltransferase YP_002348015.1 3456387 R 214092 CDS YP_002348016.1 218930141 1175918 complement(3457133..3458545) 1 NC_003143.1 mannose-1-phosphate guanylyltransferase 3458545 manC 1175918 manC Yersinia pestis CO92 mannose-1-phosphate guanylyltransferase YP_002348016.1 3457133 R 214092 CDS YP_002348017.1 218930142 1175921 complement(3460841..3461854) 1 NC_003143.1 mannosyltransferase 3461854 wbyK 1175921 wbyK Yersinia pestis CO92 mannosyltransferase YP_002348017.1 3460841 R 214092 CDS YP_002348018.1 218930143 1175923 complement(3463321..3464463) 1 NC_003143.1 mannosyltransferase 3464463 wbyJ 1175923 wbyJ Yersinia pestis CO92 mannosyltransferase YP_002348018.1 3463321 R 214092 CDS YP_002348019.1 218930144 1175925 complement(3465567..3466910) 1 NC_003143.1 O-unit flippase 3466910 wzx 1175925 wzx Yersinia pestis CO92 O-unit flippase YP_002348019.1 3465567 R 214092 CDS YP_002348020.1 218930145 1175926 complement(3466984..3468267) 1 NC_003143.1 hypothetical protein 3468267 wbyH 1175926 wbyH Yersinia pestis CO92 hypothetical protein YP_002348020.1 3466984 R 214092 CDS YP_002348021.1 218930146 1175927 complement(3468268..3469125) 1 NC_003143.1 paratose synthase 3469125 prt 1175927 prt Yersinia pestis CO92 paratose synthase YP_002348021.1 3468268 R 214092 CDS YP_002348022.1 218930147 1175928 complement(3469162..3470475) 1 NC_003143.1 CDP-4-keto-6-deoxy-D-glucose-3-dehydratase 3470475 ddhC 1175928 ddhC Yersinia pestis CO92 CDP-4-keto-6-deoxy-D-glucose-3-dehydratase YP_002348022.1 3469162 R 214092 CDS YP_002348023.1 218930148 1175930 complement(3471573..3472358) 1 NC_003143.1 glucose-1-phosphate cytidylyltransferase 3472358 ddhA 1175930 ddhA Yersinia pestis CO92 glucose-1-phosphate cytidylyltransferase YP_002348023.1 3471573 R 214092 CDS YP_002348024.1 218930149 1175931 complement(3472384..3473373) 1 NC_003143.1 catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose; CDP-6-deoxy-delta-3,4-glucoseen reductase 3473373 ddhD 1175931 ddhD Yersinia pestis CO92 CDP-6-deoxy-delta-3,4-glucoseen reductase YP_002348024.1 3472384 R 214092 CDS YP_002348025.1 218930150 1175932 complement(3473971..3474933) 1 NC_003143.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 3474933 hemH 1175932 hemH Yersinia pestis CO92 ferrochelatase YP_002348025.1 3473971 R 214092 CDS YP_002348026.1 218930151 1175933 complement(3475023..3475667) 1 NC_003143.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 3475667 adk 1175933 adk Yersinia pestis CO92 adenylate kinase YP_002348026.1 3475023 R 214092 CDS YP_002348027.1 218930152 1175934 complement(3475894..3477768) 1 NC_003143.1 molecular chaperone; heat shock protein 90 3477768 htpG 1175934 htpG Yersinia pestis CO92 heat shock protein 90 YP_002348027.1 3475894 R 214092 CDS YP_002348028.1 218930153 1175935 complement(3477960..3478565) 1 NC_003143.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 3478565 recR 1175935 recR Yersinia pestis CO92 recombination protein RecR YP_002348028.1 3477960 R 214092 CDS YP_002348029.1 218930154 1175936 complement(3478565..3478897) 1 NC_003143.1 hypothetical protein 3478897 1175936 YPO3121 Yersinia pestis CO92 hypothetical protein YP_002348029.1 3478565 R 214092 CDS YP_002348030.1 218930155 1175937 complement(3478953..3480929) 1 NC_003143.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 3480929 dnaX 1175937 dnaX Yersinia pestis CO92 DNA polymerase III subunits gamma and tau YP_002348030.1 3478953 R 214092 CDS YP_002348031.1 218930156 1175938 complement(3481585..3482148) 1 NC_003143.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 3482148 apt 1175938 apt Yersinia pestis CO92 adenine phosphoribosyltransferase YP_002348031.1 3481585 R 214092 CDS YP_002348032.1 218930157 1175941 3484925..3485461 1 NC_003143.1 primosomal replication protein n'' 3485461 priC 1175941 priC Yersinia pestis CO92 primosomal replication protein n'' YP_002348032.1 3484925 D 214092 CDS YP_002348033.1 218930158 1175942 3485632..3485787 1 NC_003143.1 hypothetical protein 3485787 1175942 YPO3128 Yersinia pestis CO92 hypothetical protein YP_002348033.1 3485632 D 214092 CDS YP_002348034.1 218930159 1175943 complement(3486127..3489546) 1 NC_003143.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 3489546 aefA 1175943 aefA Yersinia pestis CO92 potassium efflux protein KefA YP_002348034.1 3486127 R 214092 CDS YP_002348035.1 218930160 1175944 complement(3489786..3490139) 1 NC_003143.1 hypothetical protein 3490139 1175944 YPO3130 Yersinia pestis CO92 hypothetical protein YP_002348035.1 3489786 R 214092 CDS YP_002348036.1 218930161 1175945 complement(3490152..3490808) 1 NC_003143.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 3490808 acrR 1175945 acrR Yersinia pestis CO92 DNA-binding transcriptional repressor AcrR YP_002348036.1 3490152 R 214092 CDS YP_002348037.1 218930162 1175946 3490953..3492140 1 NC_003143.1 multidrug efflux protein 3492140 acrA 1175946 acrA Yersinia pestis CO92 multidrug efflux protein YP_002348037.1 3490953 D 214092 CDS YP_002348038.1 218930163 1175947 3492157..3495309 1 NC_003143.1 multidrug efflux protein 3495309 acrB 1175947 acrB Yersinia pestis CO92 multidrug efflux protein YP_002348038.1 3492157 D 214092 CDS YP_002348039.1 218930164 1175948 3495495..3495755 1 NC_003143.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 3495755 rpmE2 1175948 rpmE2 Yersinia pestis CO92 50S ribosomal protein L31 YP_002348039.1 3495495 D 214092 CDS YP_002348040.1 218930165 1175949 3495771..3495914 1 NC_003143.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 3495914 rpmJ 1175949 rpmJ Yersinia pestis CO92 50S ribosomal protein L36 YP_002348040.1 3495771 D 214092 CDS YP_002348041.1 218930166 1175950 3496788..3497141 1 NC_003143.1 no significant database hits; hypothetical protein 3497141 1175950 YPO3136 Yersinia pestis CO92 hypothetical protein YP_002348041.1 3496788 D 214092 CDS YP_002348042.1 218930167 1175951 3497300..3497668 1 NC_003143.1 hypothetical protein 3497668 1175951 YPO3137 Yersinia pestis CO92 hypothetical protein YP_002348042.1 3497300 D 214092 CDS YP_002348043.1 218930168 1175952 3497717..3497920 1 NC_003143.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 3497920 ymoA 1175952 ymoA Yersinia pestis CO92 hemolysin expression-modulating protein YP_002348043.1 3497717 D 214092 CDS YP_002348044.1 218930169 1175954 3498652..3499197 1 NC_003143.1 6-O-methylguanine-DNA methyltransferase 3499197 1175954 YPO3139 Yersinia pestis CO92 6-O-methylguanine-DNA methyltransferase YP_002348044.1 3498652 D 214092 CDS YP_002348045.1 218930170 1175955 complement(3499333..3499854) 1 NC_003143.1 lipoprotein 3499854 ybaY 1175955 ybaY Yersinia pestis CO92 lipoprotein YP_002348045.1 3499333 R 214092 CDS YP_002348046.1 218930171 1175956 3500111..3500971 1 NC_003143.1 acyl-CoA thioesterase 3500971 tesB 1175956 tesB Yersinia pestis CO92 acyl-CoA thioesterase YP_002348046.1 3500111 D 214092 CDS YP_002348047.1 218930172 1175957 complement(3501231..3502526) 1 NC_003143.1 ammonium transporter 3502526 amtB 1175957 amtB Yersinia pestis CO92 ammonium transporter YP_002348047.1 3501231 R 214092 CDS YP_002348048.1 218930173 1175958 complement(3502560..3502898) 1 NC_003143.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 3502898 glnK 1175958 glnK Yersinia pestis CO92 nitrogen regulatory protein P-II 2 YP_002348048.1 3502560 R 214092 CDS YP_002348049.1 218930174 1175959 complement(3503308..3505131) 1 NC_003143.1 multidrug transporter membrane\ATP-binding components 3505131 mdlB 1175959 mdlB Yersinia pestis CO92 multidrug transporter membrane\ATP-binding components YP_002348049.1 3503308 R 214092 CDS YP_002348050.1 218930175 1175960 complement(3505124..3506890) 1 NC_003143.1 multidrug transporter membrane\ATP-binding components 3506890 mdlA 1175960 mdlA Yersinia pestis CO92 multidrug transporter membrane\ATP-binding components YP_002348050.1 3505124 R 214092 CDS YP_002348051.1 218930176 1175961 complement(3506992..3507453) 1 NC_003143.1 AsnC family transcriptional regulator 3507453 1175961 YPO3146 Yersinia pestis CO92 AsnC family transcriptional regulator YP_002348051.1 3506992 R 214092 CDS YP_002348052.1 218930177 1175962 3507579..3508619 1 NC_003143.1 pyridoxal-phosphate dependent protein 3508619 1175962 YPO3147 Yersinia pestis CO92 pyridoxal-phosphate dependent protein YP_002348052.1 3507579 D 214092 CDS YP_002348053.1 218930178 1175963 complement(3508831..3509652) 1 NC_003143.1 haloacid dehalogenase 3509652 1175963 YPO3148 Yersinia pestis CO92 haloacid dehalogenase YP_002348053.1 3508831 R 214092 CDS YP_002348054.1 218930179 1175964 3509757..3511460 1 NC_003143.1 hypothetical protein 3511460 1175964 YPO3149 Yersinia pestis CO92 hypothetical protein YP_002348054.1 3509757 D 214092 CDS YP_002348055.1 218930180 1175965 3511725..3512423 1 NC_003143.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 3512423 1175965 YPO3150 Yersinia pestis CO92 queuosine biosynthesis protein QueC YP_002348055.1 3511725 D 214092 CDS YP_002348056.1 218930181 1175966 complement(3512509..3512916) 1 NC_003143.1 hypothetical protein 3512916 1175966 YPO3151 Yersinia pestis CO92 hypothetical protein YP_002348056.1 3512509 R 214092 CDS YP_002348057.1 218930182 1175967 complement(3513270..3513716) 1 NC_003143.1 hypothetical protein 3513716 ybaV 1175967 ybaV Yersinia pestis CO92 hypothetical protein YP_002348057.1 3513270 R 214092 CDS YP_002348058.1 218930183 1175968 complement(3513856..3515742) 1 NC_003143.1 peptidyl-prolyl cis-trans isomerase D 3515742 ppiD 1175968 ppiD Yersinia pestis CO92 peptidyl-prolyl cis-trans isomerase D YP_002348058.1 3513856 R 214092 CDS YP_002348059.1 218930184 1175969 complement(3516043..3516315) 1 NC_003143.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 3516315 hupB 1175969 hupB Yersinia pestis CO92 transcriptional regulator HU subunit beta YP_002348059.1 3516043 R 214092 CDS YP_002348060.1 218930185 1175970 complement(3516533..3518887) 1 NC_003143.1 DNA-binding ATP-dependent protease La 3518887 lon 1175970 lon Yersinia pestis CO92 DNA-binding ATP-dependent protease La YP_002348060.1 3516533 R 214092 CDS YP_002348061.1 218930186 1175971 complement(3519082..3520353) 1 NC_003143.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 3520353 clpX 1175971 clpX Yersinia pestis CO92 ATP-dependent protease ATP-binding subunit ClpX YP_002348061.1 3519082 R 214092 CDS YP_002348062.1 218930187 1175972 complement(3520559..3521182) 1 NC_003143.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 3521182 clpP 1175972 clpP Yersinia pestis CO92 ATP-dependent Clp protease proteolytic subunit YP_002348062.1 3520559 R 214092 CDS YP_002348063.1 218930188 1175973 complement(3521644..3522948) 1 NC_003143.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 3522948 tig 1175973 tig Yersinia pestis CO92 trigger factor YP_002348063.1 3521644 R 214092 CDS YP_002348065.1 218930190 1175975 complement(3523365..3523685) 1 NC_003143.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 3523685 bolA 1175975 bolA Yersinia pestis CO92 transcriptional regulator BolA YP_002348065.1 3523365 R 214092 CDS YP_002348066.1 218930191 1175976 3524034..3524612 1 NC_003143.1 hypothetical protein 3524612 yajG 1175976 yajG Yersinia pestis CO92 hypothetical protein YP_002348066.1 3524034 D 214092 CDS YP_002348067.1 218930192 1175977 3524730..3526208 1 NC_003143.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 3526208 ampG 1175977 ampG Yersinia pestis CO92 muropeptide transporter YP_002348067.1 3524730 D 214092 CDS YP_002348068.1 218930193 1175978 3526500..3527267 1 NC_003143.1 hypothetical protein 3527267 yfeN 1175978 yfeN Yersinia pestis CO92 hypothetical protein YP_002348068.1 3526500 D 214092 CDS YP_002348069.1 218930194 1175979 3527637..3528593 1 NC_003143.1 cytochrome o ubiquinol oxidase subunit II 3528593 cyoA 1175979 cyoA Yersinia pestis CO92 cytochrome o ubiquinol oxidase subunit II YP_002348069.1 3527637 D 214092 CDS YP_002348070.1 218930195 1175980 3528598..3530589 1 NC_003143.1 cytochrome O ubiquinol oxidase subunit I 3530589 cyoB 1175980 cyoB Yersinia pestis CO92 cytochrome O ubiquinol oxidase subunit I YP_002348070.1 3528598 D 214092 CDS YP_002348071.1 218930196 1175981 3530579..3531193 1 NC_003143.1 cytochrome o ubiquinol oxidase subunit III 3531193 cyoC 1175981 cyoC Yersinia pestis CO92 cytochrome o ubiquinol oxidase subunit III YP_002348071.1 3530579 D 214092 CDS YP_002348072.1 218930197 1175982 3531193..3531525 1 NC_003143.1 cytochrome o ubiquinol oxidase subunit IV 3531525 cyoD 1175982 cyoD Yersinia pestis CO92 cytochrome o ubiquinol oxidase subunit IV YP_002348072.1 3531193 D 214092 CDS YP_002348073.1 218930198 1175983 3531536..3532426 1 NC_003143.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 3532426 cyoE 1175983 cyoE Yersinia pestis CO92 protoheme IX farnesyltransferase YP_002348073.1 3531536 D 214092 CDS YP_002348074.1 218930199 1175984 3532904..3534274 1 NC_003143.1 transporter 3534274 yajR 1175984 yajR Yersinia pestis CO92 transporter YP_002348074.1 3532904 D 214092 CDS YP_002348075.1 218930200 1175985 complement(3534398..3534889) 1 NC_003143.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 3534889 1175985 YPO3170 Yersinia pestis CO92 nucleotide-binding protein YP_002348075.1 3534398 R 214092 CDS YP_002348076.1 218930201 1175986 3535121..3536032 1 NC_003143.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 3536032 apbA 1175986 apbA Yersinia pestis CO92 2-dehydropantoate 2-reductase YP_002348076.1 3535121 D 214092 CDS YP_002348077.1 218930202 1175987 3535995..3536585 1 NC_003143.1 DJ-1 family protein 3536585 thiJ 1175987 thiJ Yersinia pestis CO92 DJ-1 family protein YP_002348077.1 3535995 D 214092 CDS YP_002348078.1 218930203 1175988 complement(3536653..3538104) 1 NC_003143.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 3538104 thiI 1175988 thiI Yersinia pestis CO92 thiamine biosynthesis protein ThiI YP_002348078.1 3536653 R 214092 CDS YP_002348080.1 218930205 1175990 3538454..3538708 1 NC_003143.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 3538708 xseB 1175990 xseB Yersinia pestis CO92 exodeoxyribonuclease VII small subunit YP_002348080.1 3538454 D 214092 CDS YP_002348081.1 218930206 1175991 3538713..3539633 1 NC_003143.1 geranyltranstransferase 3539633 ispA 1175991 ispA Yersinia pestis CO92 geranyltranstransferase YP_002348081.1 3538713 D 214092 CDS YP_002348082.1 218930207 1175992 3539789..3541648 1 NC_003143.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 3541648 dxs 1175992 dxs Yersinia pestis CO92 1-deoxy-D-xylulose-5-phosphate synthase YP_002348082.1 3539789 D 214092 CDS YP_002348083.1 218930208 1175993 complement(3541827..3542285) 1 NC_003143.1 transposase for the IS1541 insertion element 3542285 tnp 1175993 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348083.1 3541827 R 214092 CDS YP_002348084.1 218930209 1175994 complement(3542499..3542984) 1 NC_003143.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 3542984 pgpA 1175994 pgpA Yersinia pestis CO92 phosphatidylglycerophosphatase A YP_002348084.1 3542499 R 214092 CDS YP_002348085.1 218930210 1175995 complement(3542977..3543966) 1 NC_003143.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 3543966 thiL 1175995 thiL Yersinia pestis CO92 thiamine monophosphate kinase YP_002348085.1 3542977 R 214092 CDS YP_002348086.1 218930211 1175996 complement(3544207..3544623) 1 NC_003143.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 3544623 nusB 1175996 nusB Yersinia pestis CO92 transcription antitermination protein NusB YP_002348086.1 3544207 R 214092 CDS YP_002348087.1 218930212 1175997 complement(3544644..3545114) 1 NC_003143.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 3545114 ribH 1175997 ribH Yersinia pestis CO92 6,7-dimethyl-8-ribityllumazine synthase YP_002348087.1 3544644 R 214092 CDS YP_002348088.1 218930213 1175998 complement(3545250..3546359) 1 NC_003143.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 3546359 ribD 1175998 ribD Yersinia pestis CO92 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_002348088.1 3545250 R 214092 CDS YP_002348089.1 218930214 1175999 complement(3546509..3546958) 1 NC_003143.1 transcriptional regulator NrdR 3546958 nrdR 1175999 nrdR Yersinia pestis CO92 transcriptional regulator NrdR YP_002348089.1 3546509 R 214092 CDS YP_002348092.1 218930217 1176002 complement(3548648..3549106) 1 NC_003143.1 transposase for the IS1541 insertion element 3549106 tnp 1176002 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348092.1 3548648 R 214092 CDS YP_002348093.1 218930218 1176003 complement(3549313..3550281) 1 NC_003143.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 3550281 secF 1176003 secF Yersinia pestis CO92 preprotein translocase subunit SecF YP_002348093.1 3549313 R 214092 CDS YP_002348094.1 218930219 1176004 complement(3550292..3552139) 1 NC_003143.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 3552139 secD 1176004 secD Yersinia pestis CO92 preprotein translocase subunit SecD YP_002348094.1 3550292 R 214092 CDS YP_002348095.1 218930220 1176005 complement(3552167..3552502) 1 NC_003143.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 3552502 yajC 1176005 yajC Yersinia pestis CO92 preprotein translocase subunit YajC YP_002348095.1 3552167 R 214092 CDS YP_002348096.1 218930221 1176006 complement(3552614..3553738) 1 NC_003143.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 3553738 tgt 1176006 tgt Yersinia pestis CO92 queuine tRNA-ribosyltransferase YP_002348096.1 3552614 R 214092 CDS YP_002348097.1 218930222 1176007 complement(3553831..3554901) 1 NC_003143.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 3554901 queA 1176007 queA Yersinia pestis CO92 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_002348097.1 3553831 R 214092 CDS YP_002348098.1 218930223 1176008 3555104..3555685 1 NC_003143.1 hypothetical protein 3555685 1176008 YPO3193 Yersinia pestis CO92 hypothetical protein YP_002348098.1 3555104 D 214092 CDS YP_002348099.1 218930224 1176009 3555984..3556586 1 NC_003143.1 alkyl hydroperoxide reductase 3556586 ahpC 1176009 ahpC Yersinia pestis CO92 alkyl hydroperoxide reductase YP_002348099.1 3555984 D 214092 CDS YP_002348100.1 218930225 1176010 3556801..3557259 1 NC_003143.1 transposase for the IS1541 insertion element 3557259 tnp 1176010 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348100.1 3556801 D 214092 CDS YP_002348101.1 218930226 1176011 complement(3557387..3557518) 1 NC_003143.1 no significant database hits; hypothetical protein 3557518 1176011 YPO3196 Yersinia pestis CO92 hypothetical protein YP_002348101.1 3557387 R 214092 CDS YP_002348102.1 218930227 1176012 complement(3557544..3557819) 1 NC_003143.1 no significant database hits; hypothetical protein 3557819 1176012 YPO3197 Yersinia pestis CO92 hypothetical protein YP_002348102.1 3557544 R 214092 CDS YP_002348103.1 218930228 1176014 complement(3559660..3560340) 1 NC_003143.1 short chain dehydrogenase 3560340 1176014 YPO3199 Yersinia pestis CO92 short chain dehydrogenase YP_002348103.1 3559660 R 214092 CDS YP_002348104.1 218930229 1176015 complement(3560495..3562324) 1 NC_003143.1 maltodextrin glucosidase 3562324 malZ 1176015 malZ Yersinia pestis CO92 maltodextrin glucosidase YP_002348104.1 3560495 R 214092 CDS YP_002348105.1 218930230 1176016 complement(3562885..3564276) 1 NC_003143.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; permease 3564276 proY 1176016 proY Yersinia pestis CO92 permease YP_002348105.1 3562885 R 214092 CDS YP_002348106.1 218930231 1176017 complement(3564352..3565671) 1 NC_003143.1 branched-chain amino acid transport system II carrier protein 3565671 brnQ 1176017 brnQ Yersinia pestis CO92 branched-chain amino acid transport system II carrier protein YP_002348106.1 3564352 R 214092 CDS YP_002348107.1 218930232 1176018 complement(3566145..3567209) 1 NC_003143.1 phosphate binding protein 3567209 pstS 1176018 pstS Yersinia pestis CO92 phosphate binding protein YP_002348107.1 3566145 R 214092 CDS YP_002348108.1 218930233 1176019 complement(3567231..3568547) 1 NC_003143.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 3568547 phoR 1176019 phoR Yersinia pestis CO92 phosphate regulon sensor protein YP_002348108.1 3567231 R 214092 CDS YP_002348109.1 218930234 1176020 complement(3568572..3569261) 1 NC_003143.1 phosphate regulon transcriptional regulator 3569261 phoB 1176020 phoB Yersinia pestis CO92 phosphate regulon transcriptional regulator YP_002348109.1 3568572 R 214092 CDS YP_002348110.1 218930235 1176021 3569529..3570773 1 NC_003143.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease SbcD 3570773 sbcD 1176021 sbcD Yersinia pestis CO92 exonuclease SbcD YP_002348110.1 3569529 D 214092 CDS YP_008479723.1 537470187 1176022 3570770..3574477 1 NC_003143.1 hypothetical protein 3574477 1176022 YPO3207 Yersinia pestis CO92 hypothetical protein YP_008479723.1 3570770 D 214092 CDS YP_002348111.1 218930236 1176023 complement(3574487..3575269) 1 NC_003143.1 transposase/IS protein 3575269 1176023 YPO3208 Yersinia pestis CO92 transposase/IS protein YP_002348111.1 3574487 R 214092 CDS YP_002348112.1 218930237 1176024 complement(3575266..3576288) 1 NC_003143.1 transposase for insertion sequence IS100 3576288 y1093 1176024 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002348112.1 3575266 R 214092 CDS YP_002348113.1 218930238 1176025 complement(3577020..3577934) 1 NC_003143.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 3577934 1176025 YPO3211 Yersinia pestis CO92 fructokinase YP_002348113.1 3577020 R 214092 CDS YP_002348114.1 218930239 1176026 3578267..3579178 1 NC_003143.1 Required for efficient pilin antigenic variation; recombination associated protein 3579178 rdgC 1176026 rdgC Yersinia pestis CO92 recombination associated protein YP_002348114.1 3578267 D 214092 CDS YP_002348115.1 218930240 1176027 complement(3579414..3579701) 1 NC_003143.1 hypothetical protein 3579701 1176027 YPO3213 Yersinia pestis CO92 hypothetical protein YP_002348115.1 3579414 R 214092 CDS YP_002348117.1 218930242 1176029 complement(3580191..3580715) 1 NC_003143.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase II 3580715 aroL 1176029 aroL Yersinia pestis CO92 shikimate kinase II YP_002348117.1 3580191 R 214092 CDS YP_002348118.1 218930243 1176030 complement(3580962..3581519) 1 NC_003143.1 methyltransferase 3581519 1176030 YPO3216 Yersinia pestis CO92 methyltransferase YP_002348118.1 3580962 R 214092 CDS YP_002348120.1 218930245 1176032 complement(3582249..3582770) 1 NC_003143.1 hypothetical protein 3582770 1176032 YPO3218 Yersinia pestis CO92 hypothetical protein YP_002348120.1 3582249 R 214092 CDS YP_002348121.1 218930246 1176033 complement(3583016..3583285) 1 NC_003143.1 no significant database matches; hypothetical protein 3583285 1176033 YPO3219 Yersinia pestis CO92 hypothetical protein YP_002348121.1 3583016 R 214092 CDS YP_002348122.1 218930247 1176034 complement(3583468..3584226) 1 NC_003143.1 hypothetical protein 3584226 1176034 YPO3220 Yersinia pestis CO92 hypothetical protein YP_002348122.1 3583468 R 214092 CDS YP_002348123.1 218930248 1176035 complement(3584554..3585813) 1 NC_003143.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 3585813 proA 1176035 proA Yersinia pestis CO92 gamma-glutamyl phosphate reductase YP_002348123.1 3584554 R 214092 CDS YP_002348124.1 218930249 1176036 complement(3585823..3586926) 1 NC_003143.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 3586926 proB 1176036 proB Yersinia pestis CO92 gamma-glutamyl kinase YP_002348124.1 3585823 R 214092 CDS YP_002348125.1 218930250 1176037 complement(3587103..3587504) 1 NC_003143.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 3587504 crl 1176037 crl Yersinia pestis CO92 DNA-binding transcriptional regulator Crl YP_002348125.1 3587103 R 214092 CDS YP_002348126.1 218930251 1176038 complement(3587564..3588811) 1 NC_003143.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 3588811 frsA 1176038 frsA Yersinia pestis CO92 fermentation/respiration switch protein YP_002348126.1 3587564 R 214092 CDS YP_002348127.1 218930252 1176039 complement(3588938..3589396) 1 NC_003143.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 3589396 gpt 1176039 gpt Yersinia pestis CO92 xanthine-guanine phosphoribosyltransferase YP_002348127.1 3588938 R 214092 CDS YP_002348128.1 218930253 1176040 3589823..3590128 1 NC_003143.1 hypothetical protein 3590128 1176040 YPO3226 Yersinia pestis CO92 hypothetical protein YP_002348128.1 3589823 D 214092 CDS YP_002348129.1 218930254 1176041 3590325..3591929 1 NC_003143.1 carbohydrate-binding protein 3591929 1176041 YPO3227 Yersinia pestis CO92 carbohydrate-binding protein YP_002348129.1 3590325 D 214092 CDS YP_002348130.1 218930255 1176042 complement(3592389..3593300) 1 NC_003143.1 LysR family transcriptional regulator 3593300 1176042 YPO3228 Yersinia pestis CO92 LysR family transcriptional regulator YP_002348130.1 3592389 R 214092 CDS YP_002348132.1 218930257 1176044 3595175..3596635 1 NC_003143.1 aminoacyl-histidine dipeptidase 3596635 pepD 1176044 pepD Yersinia pestis CO92 aminoacyl-histidine dipeptidase YP_002348132.1 3595175 D 214092 CDS YP_002348133.1 218930258 1176045 complement(3596749..3597807) 1 NC_003143.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 3597807 dinP 1176045 dinP Yersinia pestis CO92 DNA polymerase IV YP_002348133.1 3596749 R 214092 CDS YP_002348134.1 218930259 1176046 3598163..3599110 1 NC_003143.1 hypothetical protein 3599110 1176046 YPO3232 Yersinia pestis CO92 hypothetical protein YP_002348134.1 3598163 D 214092 CDS YP_002348135.1 218930260 1176047 complement(3599354..3599581) 1 NC_003143.1 hypothetical protein 3599581 1176047 YPO3233 Yersinia pestis CO92 hypothetical protein YP_002348135.1 3599354 R 214092 CDS YP_002348136.1 218930261 1176048 complement(3599594..3600616) 1 NC_003143.1 thiamine biosynthesis lipoprotein 3600616 apbE 1176048 apbE Yersinia pestis CO92 thiamine biosynthesis lipoprotein YP_002348136.1 3599594 R 214092 CDS YP_002348137.1 218930262 1176049 complement(3600657..3601880) 1 NC_003143.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit F 3601880 nqrF 1176049 nqrF Yersinia pestis CO92 Na(+)-translocating NADH-quinone reductase subunit F YP_002348137.1 3600657 R 214092 CDS YP_002348138.1 218930263 1176050 complement(3601896..3602492) 1 NC_003143.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.; Na(+)-translocating NADH-quinone reductase subunit E 3602492 nqrE 1176050 nqrE Yersinia pestis CO92 Na(+)-translocating NADH-quinone reductase subunit E YP_002348138.1 3601896 R 214092 CDS YP_002348139.1 218930264 1176051 complement(3602499..3603128) 1 NC_003143.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit D 3603128 nqrD 1176051 nqrD Yersinia pestis CO92 Na(+)-translocating NADH-quinone reductase subunit D YP_002348139.1 3602499 R 214092 CDS YP_002348140.1 218930265 1176052 complement(3603121..3603921) 1 NC_003143.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit C 3603921 nqrC 1176052 nqrC Yersinia pestis CO92 Na(+)-translocating NADH-quinone reductase subunit C YP_002348140.1 3603121 R 214092 CDS YP_002348141.1 218930266 1176053 complement(3603911..3605152) 1 NC_003143.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit B 3605152 nqrB 1176053 nqrB Yersinia pestis CO92 Na(+)-translocating NADH-quinone reductase subunit B YP_002348141.1 3603911 R 214092 CDS YP_002348142.1 218930267 1176054 complement(3605156..3606499) 1 NC_003143.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm; Na(+)-translocating NADH-quinone reductase subunit A 3606499 nqrA 1176054 nqrA Yersinia pestis CO92 Na(+)-translocating NADH-quinone reductase subunit A YP_002348142.1 3605156 R 214092 CDS YP_002348143.1 218930268 1176055 3606995..3607735 1 NC_003143.1 hypothetical protein 3607735 yafK 1176055 yafK Yersinia pestis CO92 hypothetical protein YP_002348143.1 3606995 D 214092 CDS YP_002348144.1 218930269 1176056 complement(3607700..3608473) 1 NC_003143.1 hypothetical protein 3608473 1176056 YPO3242 Yersinia pestis CO92 hypothetical protein YP_002348144.1 3607700 R 214092 CDS YP_002348145.1 218930270 1176057 complement(3608676..3609257) 1 NC_003143.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 3609257 gmhA 1176057 gmhA Yersinia pestis CO92 phosphoheptose isomerase YP_002348145.1 3608676 R 214092 CDS YP_002348146.1 218930271 1176058 3609497..3611944 1 NC_003143.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 3611944 fadE 1176058 fadE Yersinia pestis CO92 acyl-CoA dehydrogenase YP_002348146.1 3609497 D 214092 CDS YP_002348147.1 218930272 1176059 complement(3612116..3612862) 1 NC_003143.1 hypothetical protein 3612862 1176059 YPO3245 Yersinia pestis CO92 hypothetical protein YP_002348147.1 3612116 R 214092 CDS YP_002348148.1 218930273 1176060 complement(3612864..3614717) 1 NC_003143.1 accessory processing protein 3614717 hmwC 1176060 hmwC Yersinia pestis CO92 accessory processing protein YP_002348148.1 3612864 R 214092 CDS YP_002348149.1 218930274 1176061 complement(3614872..3620604) 1 NC_003143.1 adhesin 3620604 hmwA 1176061 hmwA Yersinia pestis CO92 adhesin YP_002348149.1 3614872 R 214092 CDS YP_002348150.1 218930275 1176062 complement(3620645..3622435) 1 NC_003143.1 surface-exposed protein 3622435 hxuB 1176062 hxuB Yersinia pestis CO92 surface-exposed protein YP_002348150.1 3620645 R 214092 CDS YP_002348151.1 218930276 1176063 complement(3623524..3624816) 1 NC_003143.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 3624816 1176063 YPO3249 Yersinia pestis CO92 allantoate amidohydrolase YP_002348151.1 3623524 R 214092 CDS YP_002348152.1 218930277 1176065 3625344..3626366 1 NC_003143.1 transposase for insertion sequence IS100 3626366 y1093 1176065 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002348152.1 3625344 D 214092 CDS YP_002348153.1 218930278 1176066 3626363..3627145 1 NC_003143.1 transposase/IS protein 3627145 1176066 YPO3252 Yersinia pestis CO92 transposase/IS protein YP_002348153.1 3626363 D 214092 CDS YP_002348154.1 218930279 1176067 complement(3628151..3628897) 1 NC_003143.1 amino acid ABC transporter ATP-binding protein 3628897 1176067 YPO3254 Yersinia pestis CO92 amino acid ABC transporter ATP-binding protein YP_002348154.1 3628151 R 214092 CDS YP_002348155.1 218930280 1176068 complement(3628878..3629531) 1 NC_003143.1 amino acid ABC transporter permease 3629531 1176068 YPO3255 Yersinia pestis CO92 amino acid ABC transporter permease YP_002348155.1 3628878 R 214092 CDS YP_002348156.1 218930281 1176069 complement(3629528..3630196) 1 NC_003143.1 amino acid ABC transporter permease 3630196 1176069 YPO3256 Yersinia pestis CO92 amino acid ABC transporter permease YP_002348156.1 3629528 R 214092 CDS YP_002348157.1 218930282 1176070 complement(3630209..3630997) 1 NC_003143.1 amino acid ABC transporter substrate-binding protein 3630997 1176070 YPO3257 Yersinia pestis CO92 amino acid ABC transporter substrate-binding protein YP_002348157.1 3630209 R 214092 CDS YP_002348159.1 218930284 1176072 complement(3631325..3632170) 1 NC_003143.1 rpiR family transcriptional regulator 3632170 1176072 YPO3259 Yersinia pestis CO92 rpiR family transcriptional regulator YP_002348159.1 3631325 R 214092 CDS YP_002348160.1 218930285 1176073 3632468..3632671 1 NC_003143.1 no significant database hits; hypothetical protein 3632671 1176073 YPO3260 Yersinia pestis CO92 hypothetical protein YP_002348160.1 3632468 D 214092 CDS YP_002348161.1 218930286 1176074 3632668..3634065 1 NC_003143.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 3634065 1176074 YPO3261 Yersinia pestis CO92 amidase YP_002348161.1 3632668 D 214092 CDS YP_002348162.1 218930287 1176075 3634094..3634561 1 NC_003143.1 no significant database hits; hypothetical protein 3634561 1176075 YPO3262 Yersinia pestis CO92 hypothetical protein YP_002348162.1 3634094 D 214092 CDS YP_002348163.1 218930288 1176076 3634789..3635988 1 NC_003143.1 sugar transporter 3635988 1176076 YPO3263 Yersinia pestis CO92 sugar transporter YP_002348163.1 3634789 D 214092 CDS YP_002348164.1 218930289 1176077 3636148..3636921 1 NC_003143.1 amino acid transporter 3636921 1176077 YPO3264 Yersinia pestis CO92 amino acid transporter YP_002348164.1 3636148 D 214092 CDS YP_002348165.1 218930290 1176078 3636918..3637259 1 NC_003143.1 hypothetical protein 3637259 1176078 YPO3265 Yersinia pestis CO92 hypothetical protein YP_002348165.1 3636918 D 214092 CDS YP_002348166.1 218930291 1176079 3637431..3637943 1 NC_003143.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 3637943 emrR 1176079 emrR Yersinia pestis CO92 transcriptional repressor MprA YP_002348166.1 3637431 D 214092 CDS YP_002348167.1 218930292 1176080 3638327..3639499 1 NC_003143.1 multidrug resistance protein A 3639499 emrA 1176080 emrA Yersinia pestis CO92 multidrug resistance protein A YP_002348167.1 3638327 D 214092 CDS YP_002348168.1 218930293 1176081 3639538..3641073 1 NC_003143.1 multidrug resistance protein B 3641073 emrB 1176081 emrB Yersinia pestis CO92 multidrug resistance protein B YP_002348168.1 3639538 D 214092 CDS YP_002348169.1 218930294 1176082 complement(3641196..3642362) 1 NC_003143.1 methyltransferase 3642362 yfiF 1176082 yfiF Yersinia pestis CO92 methyltransferase YP_002348169.1 3641196 R 214092 CDS YP_002348170.1 218930295 1176083 3642614..3643051 1 NC_003143.1 thioredoxin 3643051 trxC 1176083 trxC Yersinia pestis CO92 thioredoxin YP_002348170.1 3642614 D 214092 CDS YP_002348171.1 218930296 1176084 3643221..3643970 1 NC_003143.1 hypothetical protein 3643970 1176084 YPO3271 Yersinia pestis CO92 hypothetical protein YP_002348171.1 3643221 D 214092 CDS YP_002348172.1 218930297 1176085 3644013..3646655 1 NC_003143.1 acetyltransferase 3646655 yfiQ 1176085 yfiQ Yersinia pestis CO92 acetyltransferase YP_002348172.1 3644013 D 214092 CDS YP_002348173.1 218930298 1176086 3646828..3648186 1 NC_003143.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 3648186 pssA 1176086 pssA Yersinia pestis CO92 phosphatidylserine synthase YP_002348173.1 3646828 D 214092 CDS YP_002348174.1 218930299 1176087 3648248..3648589 1 NC_003143.1 hypothetical protein 3648589 1176087 YPO3274 Yersinia pestis CO92 hypothetical protein YP_002348174.1 3648248 D 214092 CDS YP_008479724.1 537470188 16744772 3654181..3654366 1 NC_003143.1 hypothetical protein 3654366 16744772 YPO3274a Yersinia pestis CO92 hypothetical protein YP_008479724.1 3654181 D 214092 CDS YP_002348175.1 218930300 1176093 complement(3654692..3657265) 1 NC_003143.1 protein disaggregation chaperone 3657265 clpB 1176093 clpB Yersinia pestis CO92 protein disaggregation chaperone YP_002348175.1 3654692 R 214092 CDS YP_002348176.1 218930301 1176094 complement(3657395..3658126) 1 NC_003143.1 hypothetical protein 3658126 1176094 YPO3276 Yersinia pestis CO92 hypothetical protein YP_002348176.1 3657395 R 214092 CDS YP_002348177.1 218930302 1176095 complement(3658128..3659105) 1 NC_003143.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 3659105 rluD 1176095 rluD Yersinia pestis CO92 23S rRNA pseudouridine synthase D YP_002348177.1 3658128 R 214092 CDS YP_002348178.1 218930303 1176096 3659241..3659972 1 NC_003143.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 3659972 yfiO 1176096 yfiO Yersinia pestis CO92 outer membrane protein assembly complex subunit YfiO YP_002348178.1 3659241 D 214092 CDS YP_002348179.1 218930304 1176097 3660327..3660689 1 NC_003143.1 sigma 54 modulation protein 3660689 yfiA 1176097 yfiA Yersinia pestis CO92 sigma 54 modulation protein YP_002348179.1 3660327 D 214092 CDS YP_002348180.1 218930305 1176098 complement(3661020..3661478) 1 NC_003143.1 transposase for the IS1541 insertion element 3661478 tnp 1176098 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348180.1 3661020 R 214092 CDS YP_002348181.1 218930306 1176100 3662781..3663803 1 NC_003143.1 transposase for insertion sequence IS100 3663803 y1093 1176100 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002348181.1 3662781 D 214092 CDS YP_002348182.1 218930307 1176101 3663800..3664582 1 NC_003143.1 transposase/IS protein 3664582 1176101 YPO3283 Yersinia pestis CO92 transposase/IS protein YP_002348182.1 3663800 D 214092 CDS YP_002348183.1 218930308 1176102 complement(3664982..3666103) 1 NC_003143.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 3666103 tyrA 1176102 tyrA Yersinia pestis CO92 bifunctional chorismate mutase/prephenate dehydrogenase YP_002348183.1 3664982 R 214092 CDS YP_002348184.1 218930309 1176103 complement(3666116..3667186) 1 NC_003143.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 3667186 aroF 1176103 aroF Yersinia pestis CO92 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002348184.1 3666116 R 214092 CDS YP_002348185.1 218930310 1176104 3667419..3668135 1 NC_003143.1 unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT 3668135 1176104 YPO3287 Yersinia pestis CO92 two-component response-regulatory protein YehT YP_002348185.1 3667419 D 214092 CDS YP_002348186.1 218930311 1176106 3670231..3670998 1 NC_003143.1 hypothetical protein 3670998 ydiY 1176106 ydiY Yersinia pestis CO92 hypothetical protein YP_002348186.1 3670231 D 214092 CDS YP_002348187.1 218930312 1176107 complement(3671301..3671759) 1 NC_003143.1 transposase for the IS1541 insertion element 3671759 tnp 1176107 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348187.1 3671301 R 214092 CDS YP_002348188.1 218930313 1176108 complement(3671971..3672318) 1 NC_003143.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 3672318 rplS 1176108 rplS Yersinia pestis CO92 50S ribosomal protein L19 YP_002348188.1 3671971 R 214092 CDS YP_002348189.1 218930314 1176109 complement(3672399..3673139) 1 NC_003143.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 3673139 trmD 1176109 trmD Yersinia pestis CO92 tRNA (guanine-N(1)-)-methyltransferase YP_002348189.1 3672399 R 214092 CDS YP_002348190.1 218930315 1176110 complement(3673178..3673726) 1 NC_003143.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 3673726 rimM 1176110 rimM Yersinia pestis CO92 16S rRNA-processing protein RimM YP_002348190.1 3673178 R 214092 CDS YP_002348191.1 218930316 1176111 complement(3673748..3673996) 1 NC_003143.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 3673996 rpsP 1176111 rpsP Yersinia pestis CO92 30S ribosomal protein S16 YP_002348191.1 3673748 R 214092 CDS YP_002348192.1 218930317 1176112 complement(3674224..3675585) 1 NC_003143.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 3675585 ffh 1176112 ffh Yersinia pestis CO92 signal recognition particle protein YP_002348192.1 3674224 R 214092 CDS YP_002348193.1 218930318 1176113 3675649..3676542 1 NC_003143.1 hypothetical protein 3676542 corE 1176113 corE Yersinia pestis CO92 hypothetical protein YP_002348193.1 3675649 D 214092 CDS YP_002348194.1 218930319 1176114 3676704..3677894 1 NC_003143.1 hypothetical protein 3677894 1176114 YPO3298 Yersinia pestis CO92 hypothetical protein YP_002348194.1 3676704 D 214092 CDS YP_002348195.1 218930320 1176115 complement(3678032..3678490) 1 NC_003143.1 transposase for the IS1541 insertion element 3678490 tnp 1176115 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348195.1 3678032 R 214092 CDS YP_002348196.1 218930321 1176116 complement(3678694..3679209) 1 NC_003143.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 3679209 luxS 1176116 luxS Yersinia pestis CO92 S-ribosylhomocysteinase YP_002348196.1 3678694 R 214092 CDS YP_002348197.1 218930322 1176117 complement(3679377..3680936) 1 NC_003143.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 3680936 gshA 1176117 gshA Yersinia pestis CO92 glutamate--cysteine ligase YP_002348197.1 3679377 R 214092 CDS YP_002348198.1 218930323 1176118 complement(3681019..3681447) 1 NC_003143.1 hypothetical protein 3681447 yqaA 1176118 yqaA Yersinia pestis CO92 hypothetical protein YP_002348198.1 3681019 R 214092 CDS YP_002348199.1 218930324 1176119 complement(3681444..3682010) 1 NC_003143.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 3682010 yqaB 1176119 yqaB Yersinia pestis CO92 fructose-1-phosphatase YP_002348199.1 3681444 R 214092 CDS YP_002348200.1 218930325 1176123 complement(3683279..3683464) 1 NC_003143.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 3683464 csrA 1176123 csrA Yersinia pestis CO92 carbon storage regulator YP_002348200.1 3683279 R 214092 CDS YP_002348201.1 218930326 1176124 complement(3683714..3686341) 1 NC_003143.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 3686341 alaS 1176124 alaS Yersinia pestis CO92 alanyl-tRNA synthetase YP_002348201.1 3683714 R 214092 CDS YP_002348202.1 218930327 1176125 complement(3686481..3687044) 1 NC_003143.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 3687044 recX 1176125 recX Yersinia pestis CO92 recombination regulator RecX YP_002348202.1 3686481 R 214092 CDS YP_002348203.1 218930328 1176126 complement(3687182..3688252) 1 NC_003143.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 3688252 recA 1176126 recA Yersinia pestis CO92 recombinase A YP_002348203.1 3687182 R 214092 CDS YP_002348204.1 218930329 1176127 complement(3688367..3688855) 1 NC_003143.1 competence damage-inducible protein A 3688855 1176127 YPO3308 Yersinia pestis CO92 competence damage-inducible protein A YP_002348204.1 3688367 R 214092 CDS YP_002348205.1 218930330 1176128 3689172..3690512 1 NC_003143.1 hypothetical protein 3690512 1176128 YPO3309 Yersinia pestis CO92 hypothetical protein YP_002348205.1 3689172 D 214092 CDS YP_002348206.1 218930331 1176129 3690760..3691704 1 NC_003143.1 transcriptional regulator 3691704 1176129 YPO3310 Yersinia pestis CO92 transcriptional regulator YP_002348206.1 3690760 D 214092 CDS YP_002348207.1 218930332 1176130 complement(3691926..3693350) 1 NC_003143.1 hypothetical protein 3693350 1176130 YPO3311 Yersinia pestis CO92 hypothetical protein YP_002348207.1 3691926 R 214092 CDS YP_002348208.1 218930333 1176131 complement(3693371..3694858) 1 NC_003143.1 glycerol kinase 3694858 1176131 YPO3312 Yersinia pestis CO92 glycerol kinase YP_002348208.1 3693371 R 214092 CDS YP_002348209.1 218930334 1176132 complement(3694861..3695805) 1 NC_003143.1 hypothetical protein 3695805 1176132 YPO3313 Yersinia pestis CO92 hypothetical protein YP_002348209.1 3694861 R 214092 CDS YP_002348210.1 218930335 1176133 complement(3695798..3696628) 1 NC_003143.1 hypothetical protein 3696628 1176133 YPO3314 Yersinia pestis CO92 hypothetical protein YP_002348210.1 3695798 R 214092 CDS YP_002348211.1 218930336 1176134 complement(3696884..3698029) 1 NC_003143.1 sugar ABC transporter permease 3698029 rbsC 1176134 rbsC Yersinia pestis CO92 sugar ABC transporter permease YP_002348211.1 3696884 R 214092 CDS YP_002348212.1 218930337 1176135 complement(3698026..3699549) 1 NC_003143.1 sugar ABC transporter ATP-binding protein 3699549 1176135 YPO3316 Yersinia pestis CO92 sugar ABC transporter ATP-binding protein YP_002348212.1 3698026 R 214092 CDS YP_002348213.1 218930338 1176136 complement(3699549..3700166) 1 NC_003143.1 lipoprotein 3700166 1176136 YPO3317 Yersinia pestis CO92 lipoprotein YP_002348213.1 3699549 R 214092 CDS YP_002348214.1 218930339 1176137 complement(3700259..3701233) 1 NC_003143.1 sugar ABC transporter substrate-binding protein 3701233 1176137 YPO3318 Yersinia pestis CO92 sugar ABC transporter substrate-binding protein YP_002348214.1 3700259 R 214092 CDS YP_002348215.1 218930340 1176138 3701736..3703949 1 NC_003143.1 catalase-peroxidase 3703949 katY 1176138 katY Yersinia pestis CO92 catalase-peroxidase YP_002348215.1 3701736 D 214092 CDS YP_002348216.1 218930341 1176139 3704026..3704409 1 NC_003143.1 cytochrome B562 3704409 cybC 1176139 cybC Yersinia pestis CO92 cytochrome B562 YP_002348216.1 3704026 D 214092 CDS YP_002348217.1 218930342 1176140 3704557..3705087 1 NC_003143.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 3705087 cybB 1176140 cybB Yersinia pestis CO92 cytochrome b561 YP_002348217.1 3704557 D 214092 CDS YP_002348218.1 218930343 1176141 complement(3705344..3706054) 1 NC_003143.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane; twin-argninine leader-binding protein DmsD 3706054 1176141 YPO3322 Yersinia pestis CO92 twin-argninine leader-binding protein DmsD YP_002348218.1 3705344 R 214092 CDS YP_002348219.1 218930344 1176142 complement(3706200..3707060) 1 NC_003143.1 anaerobic dimethyl sulfoxide reductase subunit C 3707060 dmsC 1176142 dmsC Yersinia pestis CO92 anaerobic dimethyl sulfoxide reductase subunit C YP_002348219.1 3706200 R 214092 CDS YP_002348220.1 218930345 1176143 complement(3707062..3707679) 1 NC_003143.1 anaerobic dimethyl sulfoxide reductase subunit B 3707679 dmsB 1176143 dmsB Yersinia pestis CO92 anaerobic dimethyl sulfoxide reductase subunit B YP_002348220.1 3707062 R 214092 CDS YP_002348221.1 218930346 1176144 complement(3707691..3710141) 1 NC_003143.1 anaerobic dimethyl sulfoxide reductase subunit A 3710141 dmsA 1176144 dmsA Yersinia pestis CO92 anaerobic dimethyl sulfoxide reductase subunit A YP_002348221.1 3707691 R 214092 CDS YP_002348222.1 218930347 1176145 complement(3710604..3711299) 1 NC_003143.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3711299 araD 1176145 araD Yersinia pestis CO92 L-ribulose-5-phosphate 4-epimerase YP_002348222.1 3710604 R 214092 CDS YP_002348223.1 218930348 1176146 3712002..3712811 1 NC_003143.1 deoR family regulatory protein 3712811 fucR 1176146 fucR Yersinia pestis CO92 deoR family regulatory protein YP_002348223.1 3712002 D 214092 CDS YP_002348224.1 218930349 1176147 3712873..3713976 1 NC_003143.1 sugar ABC transporter substrate-binding protein 3713976 1176147 YPO3328 Yersinia pestis CO92 sugar ABC transporter substrate-binding protein YP_002348224.1 3712873 D 214092 CDS YP_002348225.1 218930350 1176148 3714227..3714685 1 NC_003143.1 transposase for the IS1541 insertion element 3714685 tnp 1176148 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348225.1 3714227 D 214092 CDS YP_002348226.1 218930351 1176149 3714836..3716350 1 NC_003143.1 sugar ABC transporter ATP-binding protein 3716350 1176149 YPO3330 Yersinia pestis CO92 sugar ABC transporter ATP-binding protein YP_002348226.1 3714836 D 214092 CDS YP_002348227.1 218930352 1176150 3716343..3717332 1 NC_003143.1 sugar ABC transporter permease 3717332 1176150 YPO3331 Yersinia pestis CO92 sugar ABC transporter permease YP_002348227.1 3716343 D 214092 CDS YP_002348228.1 218930353 1176151 3717345..3718382 1 NC_003143.1 sugar ABC transporter permease 3718382 1176151 YPO3332 Yersinia pestis CO92 sugar ABC transporter permease YP_002348228.1 3717345 D 214092 CDS YP_002348229.1 218930354 1176152 3718588..3719469 1 NC_003143.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 3719469 sgbU 1176152 sgbU Yersinia pestis CO92 L-xylulose 5-phosphate 3-epimerase YP_002348229.1 3718588 D 214092 CDS YP_002348230.1 218930355 1176153 3719480..3720976 1 NC_003143.1 L-xylulose kinase 3720976 lyx 1176153 lyx Yersinia pestis CO92 L-xylulose kinase YP_002348230.1 3719480 D 214092 CDS YP_002348231.1 218930356 1176154 3721374..3723017 1 NC_003143.1 fumarate hydratase, class I 3723017 fumA 1176154 fumA Yersinia pestis CO92 fumarate hydratase, class I YP_002348231.1 3721374 D 214092 CDS YP_002348232.1 218930357 1176155 3723146..3723451 1 NC_003143.1 hypothetical protein 3723451 1176155 YPO3336 Yersinia pestis CO92 hypothetical protein YP_002348232.1 3723146 D 214092 CDS YP_002348233.1 218930358 1176156 3723448..3724233 1 NC_003143.1 methionine aminopeptidase 3724233 map 1176156 map Yersinia pestis CO92 methionine aminopeptidase YP_002348233.1 3723448 D 214092 CDS YP_002348234.1 218930359 1176157 complement(3724591..3725778) 1 NC_003143.1 hypothetical protein 3725778 1176157 YPO3339 Yersinia pestis CO92 hypothetical protein YP_002348234.1 3724591 R 214092 CDS YP_008479725.1 537470189 16744773 3728426..3728731 1 NC_003143.1 hypothetical protein 3728731 16744773 YPO3341a Yersinia pestis CO92 hypothetical protein YP_008479725.1 3728426 D 214092 CDS YP_002348235.1 218930360 1176159 3728968..3730347 1 NC_003143.1 cytochrome C peroxidase 3730347 yhjA 1176159 yhjA Yersinia pestis CO92 cytochrome C peroxidase YP_002348235.1 3728968 D 214092 CDS YP_002348236.1 218930361 1176160 3730412..3731182 1 NC_003143.1 ABC transporter substrate-binding protein 3731182 1176160 YPO3343 Yersinia pestis CO92 ABC transporter substrate-binding protein YP_002348236.1 3730412 D 214092 CDS YP_002348237.1 218930362 1176161 3731603..3731809 1 NC_003143.1 hypothetical protein 3731809 1176161 YPO3344 Yersinia pestis CO92 hypothetical protein YP_002348237.1 3731603 D 214092 CDS YP_002348238.1 218930363 1176162 3732005..3732283 1 NC_003143.1 no significant database hits; hypothetical protein 3732283 1176162 YPO3345 Yersinia pestis CO92 hypothetical protein YP_002348238.1 3732005 D 214092 CDS YP_002348239.1 218930364 1176163 3732530..3732871 1 NC_003143.1 regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 3732871 arsR 1176163 arsR Yersinia pestis CO92 DNA-binding transcriptional repressor ArsR YP_002348239.1 3732530 D 214092 CDS YP_002348240.1 218930365 1176164 3732956..3734245 1 NC_003143.1 arsenical pump membrane protein 3734245 arsB 1176164 arsB Yersinia pestis CO92 arsenical pump membrane protein YP_002348240.1 3732956 D 214092 CDS YP_002348241.1 218930366 1176165 3734812..3735771 1 NC_003143.1 transcriptional regulator 3735771 1176165 YPO3348 Yersinia pestis CO92 transcriptional regulator YP_002348241.1 3734812 D 214092 CDS YP_002348242.1 218930367 1176166 complement(3735892..3736566) 1 NC_003143.1 hypothetical protein 3736566 1176166 YPO3349 Yersinia pestis CO92 hypothetical protein YP_002348242.1 3735892 R 214092 CDS YP_002348243.1 218930368 1176167 complement(3736573..3737574) 1 NC_003143.1 dihydroxyacetone kinase 3737574 dhaK 1176167 dhaK Yersinia pestis CO92 dihydroxyacetone kinase YP_002348243.1 3736573 R 214092 CDS YP_002348244.1 218930369 1176168 complement(3737661..3738431) 1 NC_003143.1 short chain dehydrogenase 3738431 1176168 YPO3351 Yersinia pestis CO92 short chain dehydrogenase YP_002348244.1 3737661 R 214092 CDS YP_002348245.1 218930370 1176169 complement(3738495..3739610) 1 NC_003143.1 zinc-binding dehydrogenase 3739610 ydjJ 1176169 ydjJ Yersinia pestis CO92 zinc-binding dehydrogenase YP_002348245.1 3738495 R 214092 CDS YP_002348246.1 218930371 1176170 3740093..3740548 1 NC_003143.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 3740548 rpiB 1176170 rpiB Yersinia pestis CO92 ribose-5-phosphate isomerase B YP_002348246.1 3740093 D 214092 CDS YP_002348247.1 218930372 1176171 3741342..3743897 1 NC_003143.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 3743897 mutS 1176171 mutS Yersinia pestis CO92 DNA mismatch repair protein MutS YP_002348247.1 3741342 D 214092 CDS YP_002348248.1 218930373 1176172 complement(3744225..3745223) 1 NC_003143.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses; RNA polymerase sigma factor RpoS 3745223 rpoS 1176172 rpoS Yersinia pestis CO92 RNA polymerase sigma factor RpoS YP_002348248.1 3744225 R 214092 CDS YP_002348249.1 218930374 1176173 complement(3745278..3746279) 1 NC_003143.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 3746279 nlpD 1176173 nlpD Yersinia pestis CO92 lipoprotein NlpD YP_002348249.1 3745278 R 214092 CDS YP_002348250.1 218930375 1176174 complement(3746383..3747009) 1 NC_003143.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 3747009 pcm 1176174 pcm Yersinia pestis CO92 protein-L-isoaspartate O-methyltransferase YP_002348250.1 3746383 R 214092 CDS YP_002348251.1 218930376 1176175 complement(3747003..3747767) 1 NC_003143.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 3747767 surE 1176175 surE Yersinia pestis CO92 stationary phase survival protein SurE YP_002348251.1 3747003 R 214092 CDS YP_002348252.1 218930377 1176176 complement(3747745..3748794) 1 NC_003143.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 3748794 truD 1176176 truD Yersinia pestis CO92 tRNA pseudouridine synthase D YP_002348252.1 3747745 R 214092 CDS YP_002348253.1 218930378 1176177 complement(3748805..3749293) 1 NC_003143.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3749293 ispF 1176177 ispF Yersinia pestis CO92 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_002348253.1 3748805 R 214092 CDS YP_002348254.1 218930379 1176178 complement(3749432..3750157) 1 NC_003143.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3750157 ispD 1176178 ispD Yersinia pestis CO92 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002348254.1 3749432 R 214092 CDS YP_002348255.1 218930380 1176179 complement(3750161..3750481) 1 NC_003143.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 3750481 ftsB 1176179 ftsB Yersinia pestis CO92 cell division protein FtsB YP_002348255.1 3750161 R 214092 CDS YP_002348256.1 218930381 1176180 complement(3750795..3751112) 1 NC_003143.1 hypothetical protein 3751112 ygbE 1176180 ygbE Yersinia pestis CO92 hypothetical protein YP_002348256.1 3750795 R 214092 CDS YP_002348257.1 218930382 1176181 complement(3751303..3751944) 1 NC_003143.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 3751944 cysC 1176181 cysC Yersinia pestis CO92 adenylylsulfate kinase YP_002348257.1 3751303 R 214092 CDS YP_002348258.1 218930383 1176182 complement(3751946..3753382) 1 NC_003143.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 3753382 cysN 1176182 cysN Yersinia pestis CO92 sulfate adenylyltransferase subunit 1 YP_002348258.1 3751946 R 214092 CDS YP_002348259.1 218930384 1176183 complement(3753475..3754383) 1 NC_003143.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 3754383 cysD 1176183 cysD Yersinia pestis CO92 sulfate adenylyltransferase subunit 2 YP_002348259.1 3753475 R 214092 CDS YP_002348260.1 218930385 1176184 complement(3754394..3755812) 1 NC_003143.1 siroheme synthase 3755812 cysG 1176184 cysG Yersinia pestis CO92 siroheme synthase YP_002348260.1 3754394 R 214092 CDS YP_002348261.1 218930386 1176185 complement(3756113..3756379) 1 NC_003143.1 no significant database matches; hypothetical protein 3756379 1176185 YPO3368 Yersinia pestis CO92 hypothetical protein YP_002348261.1 3756113 R 214092 CDS YP_008479726.1 537470190 16744774 3756403..3756603 1 NC_003143.1 hypothetical protein 3756603 16744774 YPO3368a Yersinia pestis CO92 hypothetical protein YP_008479726.1 3756403 D 214092 CDS YP_002348262.1 218930387 1176186 3756778..3757185 1 NC_003143.1 hypothetical protein 3757185 1176186 YPO3369 Yersinia pestis CO92 hypothetical protein YP_002348262.1 3756778 D 214092 CDS YP_002348263.1 218930388 1176188 complement(3758151..3759881) 1 NC_003143.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 3759881 cysI 1176188 cysI Yersinia pestis CO92 sulfite reductase subunit beta YP_002348263.1 3758151 R 214092 CDS YP_002348264.1 218930389 1176189 complement(3759881..3761701) 1 NC_003143.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 3761701 cysJ 1176189 cysJ Yersinia pestis CO92 sulfite reductase subunit alpha YP_002348264.1 3759881 R 214092 CDS YP_002348265.1 218930390 1176190 3762094..3762453 1 NC_003143.1 6-pyruvoyl tetrahydrobiopterin synthase 3762453 ygcM 1176190 ygcM Yersinia pestis CO92 6-pyruvoyl tetrahydrobiopterin synthase YP_002348265.1 3762094 D 214092 CDS YP_002348266.1 218930391 1176191 complement(3762687..3763358) 1 NC_003143.1 hypothetical protein 3763358 1176191 YPO3374 Yersinia pestis CO92 hypothetical protein YP_002348266.1 3762687 R 214092 CDS YP_002348267.1 218930392 1176192 complement(3763462..3764067) 1 NC_003143.1 superoxide dismutase 3764067 sodC 1176192 sodC Yersinia pestis CO92 superoxide dismutase YP_002348267.1 3763462 R 214092 CDS YP_002348268.1 218930393 1176193 complement(3764439..3765734) 1 NC_003143.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 3765734 eno 1176193 eno Yersinia pestis CO92 phosphopyruvate hydratase YP_002348268.1 3764439 R 214092 CDS YP_002348269.1 218930394 1176194 complement(3765815..3767452) 1 NC_003143.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 3767452 pyrG 1176194 pyrG Yersinia pestis CO92 CTP synthetase YP_002348269.1 3765815 R 214092 CDS YP_002348270.1 218930395 1176195 complement(3767664..3768506) 1 NC_003143.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 3768506 mazG 1176195 mazG Yersinia pestis CO92 nucleoside triphosphate pyrophosphohydrolase YP_002348270.1 3767664 R 214092 CDS YP_002348272.1 218930397 1176197 complement(3768708..3770942) 1 NC_003143.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 3770942 relA 1176197 relA Yersinia pestis CO92 GDP/GTP pyrophosphokinase YP_002348272.1 3768708 R 214092 CDS YP_002348273.1 218930398 1176198 3771386..3774178 1 NC_003143.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 3774178 barA 1176198 barA Yersinia pestis CO92 hybrid sensory histidine kinase BarA YP_002348273.1 3771386 D 214092 CDS YP_002348274.1 218930399 1176199 complement(3774353..3775798) 1 NC_003143.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 3775798 gsrA 1176199 gsrA Yersinia pestis CO92 serine endoprotease YP_002348274.1 3774353 R 214092 CDS YP_002348275.1 218930400 1176200 complement(3775996..3777516) 1 NC_003143.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 3777516 dgt 1176200 dgt Yersinia pestis CO92 deoxyguanosinetriphosphate triphosphohydrolase YP_002348275.1 3775996 R 214092 CDS YP_002348276.1 218930401 1176201 3777810..3778511 1 NC_003143.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 3778511 mtn 1176201 mtn Yersinia pestis CO92 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002348276.1 3777810 D 214092 CDS YP_002348277.1 218930402 1176202 3778511..3779353 1 NC_003143.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 3779353 btuF 1176202 btuF Yersinia pestis CO92 vitamin B12-transporter protein BtuF YP_002348277.1 3778511 D 214092 CDS YP_002348278.1 218930403 1176203 3779353..3779967 1 NC_003143.1 hypothetical protein 3779967 yadS 1176203 yadS Yersinia pestis CO92 hypothetical protein YP_002348278.1 3779353 D 214092 CDS YP_002348279.1 218930404 1176204 complement(3780252..3780596) 1 NC_003143.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 3780596 1176204 YPO3387 Yersinia pestis CO92 iron-sulfur cluster insertion protein ErpA YP_002348279.1 3780252 R 214092 CDS YP_002348280.1 218930405 1176205 complement(3780732..3782168) 1 NC_003143.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 3782168 yadQ 1176205 yadQ Yersinia pestis CO92 chloride channel protein YP_002348280.1 3780732 R 214092 CDS YP_002348281.1 218930406 1176206 3782549..3783829 1 NC_003143.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 3783829 hemL 1176206 hemL Yersinia pestis CO92 glutamate-1-semialdehyde aminotransferase YP_002348281.1 3782549 D 214092 CDS YP_002348282.1 218930407 1176207 complement(3784203..3786200) 1 NC_003143.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease 3786200 fhuB 1176207 fhuB Yersinia pestis CO92 iron-hydroxamate transporter permease YP_002348282.1 3784203 R 214092 CDS YP_002348283.1 218930408 1176208 complement(3786197..3787285) 1 NC_003143.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 3787285 fhuD 1176208 fhuD Yersinia pestis CO92 iron-hydroxamate transporter substrate-binding subunit YP_002348283.1 3786197 R 214092 CDS YP_002348284.1 218930409 1176209 complement(3787285..3788079) 1 NC_003143.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding protein 3788079 fhuC 1176209 fhuC Yersinia pestis CO92 iron-hydroxamate transporter ATP-binding protein YP_002348284.1 3787285 R 214092 CDS YP_002348285.1 218930410 1176210 complement(3788401..3790875) 1 NC_003143.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 3790875 mrcB 1176210 mrcB Yersinia pestis CO92 penicillin-binding protein 1b YP_002348285.1 3788401 R 214092 CDS YP_002348286.1 218930411 1176211 complement(3790984..3793542) 1 NC_003143.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 3793542 hrpB 1176211 hrpB Yersinia pestis CO92 ATP-dependent RNA helicase HrpB YP_002348286.1 3790984 R 214092 CDS YP_002348287.1 218930412 1176212 3793586..3794161 1 NC_003143.1 2'-5' RNA ligase 3794161 ligT 1176212 ligT Yersinia pestis CO92 2'-5' RNA ligase YP_002348287.1 3793586 D 214092 CDS YP_002348288.1 218930413 1176213 3794274..3795011 1 NC_003143.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 3795011 sfsA 1176213 sfsA Yersinia pestis CO92 sugar fermentation stimulation protein A YP_002348288.1 3794274 D 214092 CDS YP_002348289.1 218930414 1176214 3795181..3795636 1 NC_003143.1 RNA polymerase-binding transcription factor 3795636 dksA 1176214 dksA Yersinia pestis CO92 RNA polymerase-binding transcription factor YP_002348289.1 3795181 D 214092 CDS YP_002348290.1 218930415 1176215 3795916..3796881 1 NC_003143.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 3796881 yadB 1176215 yadB Yersinia pestis CO92 glutamyl-Q tRNA(Asp) synthetase YP_002348290.1 3795916 D 214092 CDS YP_002348291.1 218930416 1176216 3796970..3798445 1 NC_003143.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase 3798445 pcnB 1176216 pcnB Yersinia pestis CO92 poly(A) polymerase YP_002348291.1 3796970 D 214092 CDS YP_002348292.1 218930417 1176217 3798453..3798932 1 NC_003143.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 3798932 folK 1176217 folK Yersinia pestis CO92 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_002348292.1 3798453 D 214092 CDS YP_002348293.1 218930418 1176218 3799198..3799998 1 NC_003143.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 3799998 panB 1176218 panB Yersinia pestis CO92 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_002348293.1 3799198 D 214092 CDS YP_002348294.1 218930419 1176219 3800086..3800940 1 NC_003143.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 3800940 panC 1176219 panC Yersinia pestis CO92 pantoate--beta-alanine ligase YP_002348294.1 3800086 D 214092 CDS YP_002348295.1 218930420 1176220 3801351..3801731 1 NC_003143.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 3801731 panD 1176220 panD Yersinia pestis CO92 aspartate alpha-decarboxylase YP_002348295.1 3801351 D 214092 CDS YP_002348296.1 218930421 1176221 complement(3801880..3803073) 1 NC_003143.1 hypothetical protein 3803073 1176221 YPO3404 Yersinia pestis CO92 hypothetical protein YP_002348296.1 3801880 R 214092 CDS YP_002348297.1 218930422 1176222 complement(3803400..3804170) 1 NC_003143.1 ABC transporter integral membrane protein 3804170 yadH 1176222 yadH Yersinia pestis CO92 ABC transporter integral membrane protein YP_002348297.1 3803400 R 214092 CDS YP_002348298.1 218930423 1176223 complement(3804167..3805093) 1 NC_003143.1 ABC transporter ATP-binding protein 3805093 yadG 1176223 yadG Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002348298.1 3804167 R 214092 CDS YP_002348299.1 218930424 1176224 3805329..3805991 1 NC_003143.1 carbonic anhydrase 3805991 yadF 1176224 yadF Yersinia pestis CO92 carbonic anhydrase YP_002348299.1 3805329 D 214092 CDS YP_002348300.1 218930425 1176225 complement(3806145..3806681) 1 NC_003143.1 hypoxanthine phosphoribosyltransferase 3806681 1176225 YPO3408 Yersinia pestis CO92 hypoxanthine phosphoribosyltransferase YP_002348300.1 3806145 R 214092 CDS YP_002348301.1 218930426 1176226 complement(3806901..3808502) 1 NC_003143.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 3808502 yacK 1176226 yacK Yersinia pestis CO92 multicopper oxidase YP_002348301.1 3806901 R 214092 CDS YP_002348302.1 218930427 1176227 3808819..3809166 1 NC_003143.1 hypothetical protein 3809166 yacC 1176227 yacC Yersinia pestis CO92 hypothetical protein YP_002348302.1 3808819 D 214092 CDS YP_002348303.1 218930428 1176228 3809283..3810173 1 NC_003143.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 3810173 speE 1176228 speE Yersinia pestis CO92 spermidine synthase YP_002348303.1 3809283 D 214092 CDS YP_002348304.1 218930429 1176229 3810251..3811045 1 NC_003143.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 3811045 speD 1176229 speD Yersinia pestis CO92 S-adenosylmethionine decarboxylase YP_002348304.1 3810251 D 214092 CDS YP_002348305.1 218930430 1176230 3811483..3812391 1 NC_003143.1 hypothetical protein 3812391 yddG 1176230 yddG Yersinia pestis CO92 hypothetical protein YP_002348305.1 3811483 D 214092 CDS YP_002348306.1 218930431 1176231 complement(3812502..3812861) 1 NC_003143.1 hypothetical protein 3812861 1176231 YPO3414 Yersinia pestis CO92 hypothetical protein YP_002348306.1 3812502 R 214092 CDS YP_002348307.1 218930432 1176232 complement(3813160..3815757) 1 NC_003143.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 3815757 acnB 1176232 acnB Yersinia pestis CO92 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_002348307.1 3813160 R 214092 CDS YP_002348308.1 218930433 1176233 complement(3816327..3816785) 1 NC_003143.1 transposase for the IS1541 insertion element 3816785 tnp 1176233 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348308.1 3816327 R 214092 CDS YP_002348309.1 218930434 1176234 complement(3817028..3818455) 1 NC_003143.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 3818455 lpdA 1176234 lpdA Yersinia pestis CO92 dihydrolipoamide dehydrogenase YP_002348309.1 3817028 R 214092 CDS YP_002348310.1 218930435 1176235 complement(3818758..3820287) 1 NC_003143.1 dihydrolipoamide acetyltransferase 3820287 aceF 1176235 aceF Yersinia pestis CO92 dihydrolipoamide acetyltransferase YP_002348310.1 3818758 R 214092 CDS YP_002348311.1 218930436 1176236 complement(3820301..3822964) 1 NC_003143.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 3822964 aceE 1176236 aceE Yersinia pestis CO92 pyruvate dehydrogenase subunit E1 YP_002348311.1 3820301 R 214092 CDS YP_002348312.1 218930437 1176237 complement(3823160..3823924) 1 NC_003143.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 3823924 pdhR 1176237 pdhR Yersinia pestis CO92 transcriptional regulator PdhR YP_002348312.1 3823160 R 214092 CDS YP_002348313.1 218930438 1176238 3824787..3826184 1 NC_003143.1 aromatic amino acid transport protein 3826184 aroP 1176238 aroP Yersinia pestis CO92 aromatic amino acid transport protein YP_002348313.1 3824787 D 214092 CDS YP_002348314.1 218930439 1176239 complement(3826602..3827456) 1 NC_003143.1 involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 3827456 ampE 1176239 ampE Yersinia pestis CO92 regulatory protein AmpE YP_002348314.1 3826602 R 214092 CDS YP_002348315.1 218930440 1176240 complement(3827746..3828297) 1 NC_003143.1 N-acetyl-anhydromuranmyl-L-alanine amidase 3828297 ampD 1176240 ampD Yersinia pestis CO92 N-acetyl-anhydromuranmyl-L-alanine amidase YP_002348315.1 3827746 R 214092 CDS YP_002348316.1 218930441 1176241 3828410..3829318 1 NC_003143.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 3829318 nadC 1176241 nadC Yersinia pestis CO92 quinolinate phosphoribosyltransferase YP_002348316.1 3828410 D 214092 CDS YP_002348317.1 218930442 1176242 3829521..3829985 1 NC_003143.1 major pilin subunit 3829985 ppdD 1176242 ppdD Yersinia pestis CO92 major pilin subunit YP_002348317.1 3829521 D 214092 CDS YP_002348318.1 218930443 1176243 3829978..3831516 1 NC_003143.1 hypothetical protein 3831516 hofB 1176243 hofB Yersinia pestis CO92 hypothetical protein YP_002348318.1 3829978 D 214092 CDS YP_002348319.1 218930444 1176244 3831513..3832712 1 NC_003143.1 type IV pilin biogenesis protein 3832712 hofC 1176244 hofC Yersinia pestis CO92 type IV pilin biogenesis protein YP_002348319.1 3831513 D 214092 CDS YP_002348320.1 218930445 1176245 complement(3833139..3834182) 1 NC_003143.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 3834182 guaC 1176245 guaC Yersinia pestis CO92 guanosine 5'-monophosphate oxidoreductase YP_002348320.1 3833139 R 214092 CDS YP_002348322.1 218930447 1176247 3834478..3835098 1 NC_003143.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 3835098 coaE 1176247 coaE Yersinia pestis CO92 dephospho-CoA kinase YP_002348322.1 3834478 D 214092 CDS YP_002348323.1 218930448 1176248 3835095..3835847 1 NC_003143.1 hypothetical protein 3835847 1176248 YPO3431 Yersinia pestis CO92 hypothetical protein YP_002348323.1 3835095 D 214092 CDS YP_002348324.1 218930449 1176249 3836033..3836239 1 NC_003143.1 zinc-binding protein 3836239 1176249 YPO3432 Yersinia pestis CO92 zinc-binding protein YP_002348324.1 3836033 D 214092 CDS YP_002348325.1 218930450 1176250 complement(3836429..3836887) 1 NC_003143.1 transposase for the IS1541 insertion element 3836887 tnp 1176250 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348325.1 3836429 R 214092 CDS YP_002348326.1 218930451 1176251 3836998..3838020 1 NC_003143.1 transposase for insertion sequence IS100 3838020 y1093 1176251 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002348326.1 3836998 D 214092 CDS YP_002348327.1 218930452 1176252 3838017..3838799 1 NC_003143.1 transposase/IS protein 3838799 1176252 YPO3435 Yersinia pestis CO92 transposase/IS protein YP_002348327.1 3838017 D 214092 CDS YP_002348328.1 218930453 1176254 complement(3839952..3841862) 1 NC_003143.1 hypothetical protein 3841862 1176254 YPO3437 Yersinia pestis CO92 hypothetical protein YP_002348328.1 3839952 R 214092 CDS YP_002348329.1 218930454 1176255 complement(3842016..3843275) 1 NC_003143.1 integrase 3843275 intB 1176255 intB Yersinia pestis CO92 integrase YP_002348329.1 3842016 R 214092 CDS YP_002348330.1 218930455 1176257 complement(3843663..3844739) 1 NC_003143.1 hypothetical protein 3844739 1176257 YPO3439 Yersinia pestis CO92 hypothetical protein YP_002348330.1 3843663 R 214092 CDS YP_002348331.1 218930456 1176258 complement(3844739..3845833) 1 NC_003143.1 hypothetical protein 3845833 1176258 YPO3440 Yersinia pestis CO92 hypothetical protein YP_002348331.1 3844739 R 214092 CDS YP_002348332.1 218930457 1176259 3846113..3847624 1 NC_003143.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 3847624 pepA 1176259 pepA Yersinia pestis CO92 leucyl aminopeptidase YP_002348332.1 3846113 D 214092 CDS YP_002348333.1 218930458 1176260 3847775..3848224 1 NC_003143.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 3848224 holC 1176260 holC Yersinia pestis CO92 DNA polymerase III subunit chi YP_002348333.1 3847775 D 214092 CDS YP_002348334.1 218930459 1176261 3848237..3851134 1 NC_003143.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 3851134 valS 1176261 valS Yersinia pestis CO92 valyl-tRNA synthetase YP_002348334.1 3848237 D 214092 CDS YP_002348335.1 218930460 1176262 3851277..3851780 1 NC_003143.1 acetyltransferase 3851780 1176262 YPO3444 Yersinia pestis CO92 acetyltransferase YP_002348335.1 3851277 D 214092 CDS YP_002348336.1 218930461 1176263 complement(3852287..3852718) 1 NC_003143.1 hypothetical protein 3852718 1176263 YPO3445 Yersinia pestis CO92 hypothetical protein YP_002348336.1 3852287 R 214092 CDS YP_002348337.1 218930462 1176264 3852930..3853937 1 NC_003143.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I 3853937 argI 1176264 argI Yersinia pestis CO92 ornithine carbamoyltransferase subunit I YP_002348337.1 3852930 D 214092 CDS YP_002348338.1 218930463 1176265 complement(3854244..3854702) 1 NC_003143.1 hypothetical protein 3854702 1176265 YPO3447 Yersinia pestis CO92 hypothetical protein YP_002348338.1 3854244 R 214092 CDS YP_002348339.1 218930464 1176267 3857004..3858053 1 NC_003143.1 transporter, permease 3858053 1176267 YPO3450 Yersinia pestis CO92 transporter, permease YP_002348339.1 3857004 D 214092 CDS YP_002348340.1 218930465 1176268 3858072..3858908 1 NC_003143.1 transporter, permease 3858908 1176268 YPO3451 Yersinia pestis CO92 transporter, permease YP_002348340.1 3858072 D 214092 CDS YP_002348341.1 218930466 1176269 3858901..3859779 1 NC_003143.1 ABC transporter ATP-binding protein 3859779 1176269 YPO3452 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002348341.1 3858901 D 214092 CDS YP_002348342.1 218930467 1176270 3859781..3860482 1 NC_003143.1 ABC transporter ATP-binding protein 3860482 1176270 YPO3453 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002348342.1 3859781 D 214092 CDS YP_002348343.1 218930468 1176271 3860916..3863054 1 NC_003143.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 3863054 nrdD 1176271 nrdD Yersinia pestis CO92 anaerobic ribonucleoside triphosphate reductase YP_002348343.1 3860916 D 214092 CDS YP_002348344.1 218930469 1176272 3863261..3863695 1 NC_003143.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 3863695 nrdG 1176272 nrdG Yersinia pestis CO92 anaerobic ribonucleotide reductase-activating protein YP_002348344.1 3863261 D 214092 CDS YP_002348345.1 218930470 1176273 3864023..3864748 1 NC_003143.1 may be involved in phosphonate uptake and biodegradation; phosphonate metabolism transcriptional regulator PhnF 3864748 phnF 1176273 phnF Yersinia pestis CO92 phosphonate metabolism transcriptional regulator PhnF YP_002348345.1 3864023 D 214092 CDS YP_002348346.1 218930471 1176274 3864749..3865225 1 NC_003143.1 PhnG protein 3865225 phnG 1176274 phnG Yersinia pestis CO92 PhnG protein YP_002348346.1 3864749 D 214092 CDS YP_002348347.1 218930472 1176275 3865225..3865851 1 NC_003143.1 carbon-phosphorus lyase complex protein 3865851 phnH 1176275 phnH Yersinia pestis CO92 carbon-phosphorus lyase complex protein YP_002348347.1 3865225 D 214092 CDS YP_002348348.1 218930473 1176276 3865851..3867029 1 NC_003143.1 PhnI protein 3867029 phnI 1176276 phnI Yersinia pestis CO92 PhnI protein YP_002348348.1 3865851 D 214092 CDS YP_002348349.1 218930474 1176277 3867022..3867903 1 NC_003143.1 PhnJ protein 3867903 phnJ 1176277 phnJ Yersinia pestis CO92 PhnJ protein YP_002348349.1 3867022 D 214092 CDS YP_002348350.1 218930475 1176278 3867903..3868694 1 NC_003143.1 phosphonate C-P lyase system protein PhnK 3868694 phnK 1176278 phnK Yersinia pestis CO92 phosphonate C-P lyase system protein PhnK YP_002348350.1 3867903 D 214092 CDS YP_002348351.1 218930476 1176279 3869083..3869802 1 NC_003143.1 phosphonates transport ATP-binding protein 3869802 phnL 1176279 phnL Yersinia pestis CO92 phosphonates transport ATP-binding protein YP_002348351.1 3869083 D 214092 CDS YP_002348352.1 218930477 1176280 3869799..3870935 1 NC_003143.1 PhnM protein 3870935 phnM 1176280 phnM Yersinia pestis CO92 PhnM protein YP_002348352.1 3869799 D 214092 CDS YP_002348353.1 218930478 1176281 3870935..3871516 1 NC_003143.1 ribose 1,5-bisphosphokinase 3871516 phnN 1176281 phnN Yersinia pestis CO92 ribose 1,5-bisphosphokinase YP_002348353.1 3870935 D 214092 CDS YP_002348354.1 218930479 1176282 3871507..3872259 1 NC_003143.1 required for the use of phosphonates and phosphite as phosphorus sources; carbon-phosphorus lyase complex accessory protein 3872259 phnP 1176282 phnP Yersinia pestis CO92 carbon-phosphorus lyase complex accessory protein YP_002348354.1 3871507 D 214092 CDS YP_002348355.1 218930480 1176283 complement(3872272..3872910) 1 NC_003143.1 hypothetical protein 3872910 1176283 YPO3466 Yersinia pestis CO92 hypothetical protein YP_002348355.1 3872272 R 214092 CDS YP_002348356.1 218930481 1176284 complement(3873062..3873505) 1 NC_003143.1 hypothetical protein 3873505 1176284 YPO3467 Yersinia pestis CO92 hypothetical protein YP_002348356.1 3873062 R 214092 CDS YP_002348357.1 218930482 1176285 complement(3873604..3874770) 1 NC_003143.1 no significant database hits; hypothetical protein 3874770 1176285 YPO3468 Yersinia pestis CO92 hypothetical protein YP_002348357.1 3873604 R 214092 CDS YP_002348358.1 218930483 1176286 complement(3874785..3875879) 1 NC_003143.1 sugar ABC transporter ATP-binding protein 3875879 1176286 YPO3469 Yersinia pestis CO92 sugar ABC transporter ATP-binding protein YP_002348358.1 3874785 R 214092 CDS YP_002348359.1 218930484 1176287 complement(3875891..3876730) 1 NC_003143.1 sugar transport system permease 3876730 1176287 YPO3470 Yersinia pestis CO92 sugar transport system permease YP_002348359.1 3875891 R 214092 CDS YP_002348360.1 218930485 1176288 complement(3876749..3877633) 1 NC_003143.1 sugar transport system permease 3877633 1176288 YPO3471 Yersinia pestis CO92 sugar transport system permease YP_002348360.1 3876749 R 214092 CDS YP_002348361.1 218930486 1176289 complement(3877641..3878954) 1 NC_003143.1 sugar binding protein 3878954 1176289 YPO3472 Yersinia pestis CO92 sugar binding protein YP_002348361.1 3877641 R 214092 CDS YP_002348362.1 218930487 1176290 3879512..3880738 1 NC_003143.1 no significant database matches; hypothetical protein 3880738 1176290 YPO3473 Yersinia pestis CO92 hypothetical protein YP_002348362.1 3879512 D 214092 CDS YP_002348363.1 218930488 1176291 3880762..3882780 1 NC_003143.1 no significant database hits; hypothetical protein 3882780 1176291 YPO3474 Yersinia pestis CO92 hypothetical protein YP_002348363.1 3880762 D 214092 CDS YP_002348364.1 218930489 1176292 3883011..3883298 1 NC_003143.1 GIY-YIG nuclease superfamily protein 3883298 1176292 YPO3475 Yersinia pestis CO92 GIY-YIG nuclease superfamily protein YP_002348364.1 3883011 D 214092 CDS YP_002348365.1 218930490 1176293 complement(3883473..3883979) 1 NC_003143.1 acetyltransferase 3883979 1176293 YPO3476 Yersinia pestis CO92 acetyltransferase YP_002348365.1 3883473 R 214092 CDS YP_002348366.1 218930491 1176294 complement(3883973..3884494) 1 NC_003143.1 lipid carrier protein 3884494 1176294 YPO3477 Yersinia pestis CO92 lipid carrier protein YP_002348366.1 3883973 R 214092 CDS YP_002348367.1 218930492 1176295 3884575..3884700 1 NC_003143.1 doubtful CDS with no significant database hits. Very low %G+C; hypothetical protein 3884700 1176295 YPO3478 Yersinia pestis CO92 hypothetical protein YP_002348367.1 3884575 D 214092 CDS YP_002348368.1 218930493 1176296 3884810..3885805 1 NC_003143.1 protease 3885805 1176296 YPO3479 Yersinia pestis CO92 protease YP_002348368.1 3884810 D 214092 CDS YP_002348369.1 218930494 1176297 3885817..3886695 1 NC_003143.1 hypothetical protein 3886695 1176297 YPO3480 Yersinia pestis CO92 hypothetical protein YP_002348369.1 3885817 D 214092 CDS YP_002348370.1 218930495 1176298 complement(3886836..3888242) 1 NC_003143.1 outer membrane efflux lipoprotein 3888242 ibeB 1176298 ibeB Yersinia pestis CO92 outer membrane efflux lipoprotein YP_002348370.1 3886836 R 214092 CDS YP_002348371.1 218930496 1176299 complement(3888244..3891369) 1 NC_003143.1 multidrug efflux protein 3891369 1176299 YPO3482 Yersinia pestis CO92 multidrug efflux protein YP_002348371.1 3888244 R 214092 CDS YP_002348372.1 218930497 1176300 complement(3891373..3892533) 1 NC_003143.1 multidrug efflux protein 3892533 1176300 YPO3483 Yersinia pestis CO92 multidrug efflux protein YP_002348372.1 3891373 R 214092 CDS YP_002348373.1 218930498 1176301 3893041..3894096 1 NC_003143.1 hypothetical protein 3894096 1176301 YPO3484 Yersinia pestis CO92 hypothetical protein YP_002348373.1 3893041 D 214092 CDS YP_002348374.1 218930499 1176302 complement(3894351..3894662) 1 NC_003143.1 transcriptional regulator 3894662 1176302 YPO3485 Yersinia pestis CO92 transcriptional regulator YP_002348374.1 3894351 R 214092 CDS YP_002348375.1 218930500 1176303 complement(3894686..3895054) 1 NC_003143.1 hypothetical protein 3895054 1176303 YPO3486 Yersinia pestis CO92 hypothetical protein YP_002348375.1 3894686 R 214092 CDS YP_002348376.1 218930501 1176304 complement(3895097..3895270) 1 NC_003143.1 no significant database matches. doubtful CDS. Very low %GC content; hypothetical protein 3895270 1176304 YPO3487 Yersinia pestis CO92 hypothetical protein YP_002348376.1 3895097 R 214092 CDS YP_002348377.1 218930502 1176305 complement(3895290..3897284) 1 NC_003143.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 3897284 deaD 1176305 deaD Yersinia pestis CO92 ATP-dependent RNA helicase DeaD YP_002348377.1 3895290 R 214092 CDS YP_002348378.1 218930503 1176306 complement(3897471..3898355) 1 NC_003143.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 3898355 nlpI 1176306 nlpI Yersinia pestis CO92 lipoprotein NlpI YP_002348378.1 3897471 R 214092 CDS YP_002348379.1 218930504 1176307 complement(3898480..3900597) 1 NC_003143.1 polynucleotide phosphorylase 3900597 pnp 1176307 pnp Yersinia pestis CO92 polynucleotide phosphorylase YP_002348379.1 3898480 R 214092 CDS YP_002348380.1 218930505 1176308 complement(3900864..3901649) 1 NC_003143.1 transposase for insertion sequence IS1661 3901649 1176308 YPO3491 Yersinia pestis CO92 transposase for insertion sequence IS1661 YP_002348380.1 3900864 R 214092 CDS YP_002348381.1 218930506 1176309 complement(3901703..3902218) 1 NC_003143.1 insertion element IS1661 DNA-binding protein 3902218 1176309 YPO3492 Yersinia pestis CO92 insertion element IS1661 DNA-binding protein YP_002348381.1 3901703 R 214092 CDS YP_002348382.1 218930507 1176310 complement(3902305..3902574) 1 NC_003143.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3902574 rpsO 1176310 rpsO Yersinia pestis CO92 30S ribosomal protein S15 YP_002348382.1 3902305 R 214092 CDS YP_002348383.1 218930508 1176311 complement(3902696..3903670) 1 NC_003143.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3903670 truB 1176311 truB Yersinia pestis CO92 tRNA pseudouridine synthase B YP_002348383.1 3902696 R 214092 CDS YP_002348384.1 218930509 1176312 complement(3903670..3904080) 1 NC_003143.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3904080 rbfA 1176312 rbfA Yersinia pestis CO92 ribosome-binding factor A YP_002348384.1 3903670 R 214092 CDS YP_002348385.1 218930510 1176313 complement(3904146..3906800) 1 NC_003143.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3906800 infB 1176313 infB Yersinia pestis CO92 translation initiation factor IF-2 YP_002348385.1 3904146 R 214092 CDS YP_002348386.1 218930511 1176314 complement(3906825..3908312) 1 NC_003143.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3908312 nusA 1176314 nusA Yersinia pestis CO92 transcription elongation factor NusA YP_002348386.1 3906825 R 214092 CDS YP_002348387.1 218930512 1176315 complement(3908334..3908786) 1 NC_003143.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3908786 1176315 YPO3498 Yersinia pestis CO92 hypothetical protein YP_002348387.1 3908334 R 214092 CDS YP_002348388.1 218930513 1176318 complement(3909318..3909653) 1 NC_003143.1 preprotein translocase subunit SecG 3909653 secG 1176318 secG Yersinia pestis CO92 preprotein translocase subunit SecG YP_002348388.1 3909318 R 214092 CDS YP_002348389.1 218930514 1176319 complement(3909876..3911216) 1 NC_003143.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3911216 glmM 1176319 glmM Yersinia pestis CO92 phosphoglucosamine mutase YP_002348389.1 3909876 R 214092 CDS YP_002348390.1 218930515 1176320 complement(3911226..3912059) 1 NC_003143.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 3912059 folP 1176320 folP Yersinia pestis CO92 dihydropteroate synthase YP_002348390.1 3911226 R 214092 CDS YP_002348391.1 218930516 1176321 complement(3912179..3914113) 1 NC_003143.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 3914113 hflB 1176321 hflB Yersinia pestis CO92 ATP-dependent metalloprotease YP_002348391.1 3912179 R 214092 CDS YP_002348392.1 218930517 1176322 complement(3914170..3914799) 1 NC_003143.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase 3914799 rrmJ 1176322 rrmJ Yersinia pestis CO92 23S rRNA methyltransferase YP_002348392.1 3914170 R 214092 CDS YP_002348393.1 218930518 1176323 3914946..3915239 1 NC_003143.1 hypothetical protein 3915239 1176323 YPO3504 Yersinia pestis CO92 hypothetical protein YP_002348393.1 3914946 D 214092 CDS YP_002348394.1 218930519 1176324 complement(3915367..3915843) 1 NC_003143.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3915843 greA 1176324 greA Yersinia pestis CO92 transcription elongation factor GreA YP_002348394.1 3915367 R 214092 CDS YP_002348395.1 218930520 1176325 3916101..3917549 1 NC_003143.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase/endopeptidase 3917549 dacB 1176325 dacB Yersinia pestis CO92 D-alanyl-D-alanine carboxypeptidase/endopeptidase YP_002348395.1 3916101 D 214092 CDS YP_002348396.1 218930521 1176326 3917555..3918217 1 NC_003143.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 3918217 basR 1176326 basR Yersinia pestis CO92 DNA-binding transcriptional regulator BasR YP_002348396.1 3917555 D 214092 CDS YP_002348397.1 218930522 1176327 3918214..3919281 1 NC_003143.1 sensor protein BasS/PmrB 3919281 basS 1176327 basS Yersinia pestis CO92 sensor protein BasS/PmrB YP_002348397.1 3918214 D 214092 CDS YP_002348398.1 218930523 1176328 complement(3919376..3920548) 1 NC_003143.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3920548 obgE 1176328 obgE Yersinia pestis CO92 GTPase ObgE YP_002348398.1 3919376 R 214092 CDS YP_002348399.1 218930524 1176329 complement(3920549..3921535) 1 NC_003143.1 hypothetical protein 3921535 1176329 YPO3510 Yersinia pestis CO92 hypothetical protein YP_002348399.1 3920549 R 214092 CDS YP_002348400.1 218930525 1176330 complement(3921623..3921880) 1 NC_003143.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 3921880 rpmA 1176330 rpmA Yersinia pestis CO92 50S ribosomal protein L27 YP_002348400.1 3921623 R 214092 CDS YP_002348401.1 218930526 1176331 complement(3921900..3922211) 1 NC_003143.1 50S ribosomal protein L21 3922211 rplU 1176331 rplU Yersinia pestis CO92 50S ribosomal protein L21 YP_002348401.1 3921900 R 214092 CDS YP_002348402.1 218930527 1176332 3922471..3923442 1 NC_003143.1 octaprenyl diphosphate synthase 3923442 ispB 1176332 ispB Yersinia pestis CO92 octaprenyl diphosphate synthase YP_002348402.1 3922471 D 214092 CDS YP_002348403.1 218930528 1176333 complement(3923539..3923940) 1 NC_003143.1 hypothetical protein 3923940 1176333 YPO3514 Yersinia pestis CO92 hypothetical protein YP_002348403.1 3923539 R 214092 CDS YP_008479727.1 537470191 16744775 3924070..3924345 1 NC_003143.1 DNA-binding protein 3924345 16744775 YPO3514a Yersinia pestis CO92 DNA-binding protein YP_008479727.1 3924070 D 214092 CDS YP_002348405.1 218930530 1176335 complement(3924779..3925717) 1 NC_003143.1 oxidizes malate to oxaloacetate; malate dehydrogenase 3925717 mdh 1176335 mdh Yersinia pestis CO92 malate dehydrogenase YP_002348405.1 3924779 R 214092 CDS YP_002348406.1 218930531 1176336 3926181..3926651 1 NC_003143.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor ArgR 3926651 argR 1176336 argR Yersinia pestis CO92 arginine repressor ArgR YP_002348406.1 3926181 D 214092 CDS YP_002348407.1 218930532 1176337 3927040..3927303 1 NC_003143.1 hypothetical protein 3927303 1176337 YPO3518 Yersinia pestis CO92 hypothetical protein YP_002348407.1 3927040 D 214092 CDS YP_002348408.1 218930533 1176338 complement(3927599..3928981) 1 NC_003143.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 3928981 mpl 1176338 mpl Yersinia pestis CO92 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_002348408.1 3927599 R 214092 CDS YP_002348409.1 218930534 1176339 3929152..3930165 1 NC_003143.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 3930165 fbp 1176339 fbp Yersinia pestis CO92 fructose-1,6-bisphosphatase YP_002348409.1 3929152 D 214092 CDS YP_002348410.1 218930535 1176340 3930365..3930892 1 NC_003143.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 3930892 ppa 1176340 ppa Yersinia pestis CO92 inorganic pyrophosphatase YP_002348410.1 3930365 D 214092 CDS YP_002348411.1 218930536 1176341 complement(3931010..3931366) 1 NC_003143.1 hypothetical protein 3931366 1176341 YPO3522 Yersinia pestis CO92 hypothetical protein YP_002348411.1 3931010 R 214092 CDS YP_002348412.1 218930537 1176342 complement(3931369..3935286) 1 NC_003143.1 hypothetical protein 3935286 1176342 YPO3523 Yersinia pestis CO92 hypothetical protein YP_002348412.1 3931369 R 214092 CDS YP_002348413.1 218930538 1176343 complement(3935283..3937019) 1 NC_003143.1 hypothetical protein 3937019 1176343 YPO3524 Yersinia pestis CO92 hypothetical protein YP_002348413.1 3935283 R 214092 CDS YP_002348414.1 218930539 1176344 3937294..3937932 1 NC_003143.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 3937932 msrA 1176344 msrA Yersinia pestis CO92 methionine sulfoxide reductase A YP_002348414.1 3937294 D 214092 CDS YP_002348415.1 218930540 1176345 3938210..3939541 1 NC_003143.1 hypothetical protein 3939541 1176345 YPO3526 Yersinia pestis CO92 hypothetical protein YP_002348415.1 3938210 D 214092 CDS YP_002348416.1 218930541 1176346 complement(3939649..3939861) 1 NC_003143.1 hypothetical protein 3939861 1176346 YPO3527 Yersinia pestis CO92 hypothetical protein YP_002348416.1 3939649 R 214092 CDS YP_002348417.1 218930542 1176347 3940197..3940760 1 NC_003143.1 hypothetical protein 3940760 1176347 YPO3528 Yersinia pestis CO92 hypothetical protein YP_002348417.1 3940197 D 214092 CDS YP_002348418.1 218930543 1176348 complement(3940763..3941506) 1 NC_003143.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 3941506 cysQ 1176348 cysQ Yersinia pestis CO92 adenosine-3'(2'),5'-bisphosphate nucleotidase YP_002348418.1 3940763 R 214092 CDS YP_002348419.1 218930544 1176349 3941938..3943908 1 NC_003143.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase 3943908 cpdB 1176349 cpdB Yersinia pestis CO92 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase YP_002348419.1 3941938 D 214092 CDS YP_002348420.1 218930545 1176350 3944063..3944728 1 NC_003143.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 3944728 1176350 YPO3531 Yersinia pestis CO92 iron-sulfur cluster repair di-iron protein YP_002348420.1 3944063 D 214092 CDS YP_002348421.1 218930546 1176351 complement(3944826..3945446) 1 NC_003143.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 3945446 fklB 1176351 fklB Yersinia pestis CO92 peptidyl-prolyl cis-trans isomerase YP_002348421.1 3944826 R 214092 CDS YP_002348422.1 218930547 1176352 3945789..3946529 1 NC_003143.1 hypothetical protein 3946529 1176352 YPO3533 Yersinia pestis CO92 hypothetical protein YP_002348422.1 3945789 D 214092 CDS YP_002348423.1 218930548 1176353 3946669..3947124 1 NC_003143.1 no significant database matches; hypothetical protein 3947124 1176353 YPO3534 Yersinia pestis CO92 hypothetical protein YP_002348423.1 3946669 D 214092 CDS YP_002348424.1 218930549 1176354 complement(3947246..3947704) 1 NC_003143.1 transposase for the IS1541 insertion element 3947704 tnp 1176354 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348424.1 3947246 R 214092 CDS YP_002348425.1 218930550 1176355 complement(3947900..3948352) 1 NC_003143.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 3948352 rplI 1176355 rplI Yersinia pestis CO92 50S ribosomal protein L9 YP_002348425.1 3947900 R 214092 CDS YP_002348426.1 218930551 1176356 complement(3948392..3948619) 1 NC_003143.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 3948619 rpsR 1176356 rpsR Yersinia pestis CO92 30S ribosomal protein S18 YP_002348426.1 3948392 R 214092 CDS YP_002348427.1 218930552 1176357 complement(3948624..3948944) 1 NC_003143.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 3948944 priB 1176357 priB Yersinia pestis CO92 primosomal replication protein N YP_002348427.1 3948624 R 214092 CDS YP_002348428.1 218930553 1176358 complement(3948950..3949342) 1 NC_003143.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 3949342 rpsF 1176358 rpsF Yersinia pestis CO92 30S ribosomal protein S6 YP_002348428.1 3948950 R 214092 CDS YP_002348429.1 218930554 1176359 complement(3949356..3949634) 1 NC_003143.1 no significant database hits; hypothetical protein 3949634 1176359 YPO3540 Yersinia pestis CO92 hypothetical protein YP_002348429.1 3949356 R 214092 CDS YP_002348430.1 218930555 1176361 3950467..3951489 1 NC_003143.1 transposase for insertion sequence IS100 3951489 y1093 1176361 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002348430.1 3950467 D 214092 CDS YP_002348431.1 218930556 1176362 3951486..3952268 1 NC_003143.1 transposase/IS protein 3952268 1176362 YPO3543 Yersinia pestis CO92 transposase/IS protein YP_002348431.1 3951486 D 214092 CDS YP_008479728.1 537470192 1176363 3952284..3953225 1 NC_003143.1 hypothetical protein 3953225 1176363 YPO3544 Yersinia pestis CO92 hypothetical protein YP_008479728.1 3952284 D 214092 CDS YP_002348432.1 218930557 1176364 complement(3953349..3954242) 1 NC_003143.1 LysR family transcriptional regulator 3954242 1176364 YPO3545 Yersinia pestis CO92 LysR family transcriptional regulator YP_002348432.1 3953349 R 214092 CDS YP_002348433.1 218930558 1176365 3954504..3955208 1 NC_003143.1 hypothetical protein 3955208 1176365 YPO3546 Yersinia pestis CO92 hypothetical protein YP_002348433.1 3954504 D 214092 CDS YP_002348434.1 218930559 1176367 complement(3956145..3957044) 1 NC_003143.1 tetrapyrrole methylase 3957044 1176367 YPO3547 Yersinia pestis CO92 tetrapyrrole methylase YP_002348434.1 3956145 R 214092 CDS YP_002348435.1 218930560 1176368 3957107..3959080 1 NC_003143.1 hypothetical protein 3959080 1176368 YPO3548 Yersinia pestis CO92 hypothetical protein YP_002348435.1 3957107 D 214092 CDS YP_002348436.1 218930561 1176369 3959164..3959517 1 NC_003143.1 hypothetical protein 3959517 1176369 YPO3549 Yersinia pestis CO92 hypothetical protein YP_002348436.1 3959164 D 214092 CDS YP_002348437.1 218930562 1176370 3959788..3960378 1 NC_003143.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; chromosome replication initiator DnaA 3960378 1176370 YPO3550 Yersinia pestis CO92 chromosome replication initiator DnaA YP_002348437.1 3959788 D 214092 CDS YP_002348438.1 218930563 1176371 3960389..3960964 1 NC_003143.1 hypothetical protein 3960964 1176371 YPO3551 Yersinia pestis CO92 hypothetical protein YP_002348438.1 3960389 D 214092 CDS YP_002348439.1 218930564 1176372 complement(3961171..3961896) 1 NC_003143.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 3961896 mtgA 1176372 mtgA Yersinia pestis CO92 monofunctional biosynthetic peptidoglycan transglycosylase YP_002348439.1 3961171 R 214092 CDS YP_002348440.1 218930565 1176373 complement(3961893..3962546) 1 NC_003143.1 isoprenoid biosynthesis protein with amidotransferase-like domain 3962546 elbB 1176373 elbB Yersinia pestis CO92 isoprenoid biosynthesis protein with amidotransferase-like domain YP_002348440.1 3961893 R 214092 CDS YP_002348442.1 218930567 1176375 complement(3962788..3965124) 1 NC_003143.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 3965124 arcB 1176375 arcB Yersinia pestis CO92 aerobic respiration control sensor protein ArcB YP_002348442.1 3962788 R 214092 CDS YP_002348443.1 218930568 1176376 complement(3965388..3966311) 1 NC_003143.1 hypothetical protein 3966311 1176376 YPO3556 Yersinia pestis CO92 hypothetical protein YP_002348443.1 3965388 R 214092 CDS YP_002348444.1 218930569 1176377 3967134..3971600 1 NC_003143.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3971600 gltB 1176377 gltB Yersinia pestis CO92 glutamate synthase subunit alpha YP_002348444.1 3967134 D 214092 CDS YP_002348445.1 218930570 1176378 3971610..3973028 1 NC_003143.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3973028 gltD 1176378 gltD Yersinia pestis CO92 glutamate synthase subunit beta YP_002348445.1 3971610 D 214092 CDS YP_002348446.1 218930571 1176379 3973469..3973954 1 NC_003143.1 hypothetical protein 3973954 1176379 YPO3559 Yersinia pestis CO92 hypothetical protein YP_002348446.1 3973469 D 214092 CDS YP_002348447.1 218930572 1176380 complement(3974107..3974622) 1 NC_003143.1 ClpXP protease specificity-enhancing factor 3974622 sspB 1176380 sspB Yersinia pestis CO92 ClpXP protease specificity-enhancing factor YP_002348447.1 3974107 R 214092 CDS YP_002348448.1 218930573 1176381 complement(3974628..3975269) 1 NC_003143.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 3975269 sspA 1176381 sspA Yersinia pestis CO92 stringent starvation protein A YP_002348448.1 3974628 R 214092 CDS YP_002348449.1 218930574 1176382 complement(3975643..3976035) 1 NC_003143.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3976035 rpsI 1176382 rpsI Yersinia pestis CO92 30S ribosomal protein S9 YP_002348449.1 3975643 R 214092 CDS YP_002348450.1 218930575 1176383 complement(3976050..3976478) 1 NC_003143.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3976478 rplM 1176383 rplM Yersinia pestis CO92 50S ribosomal protein L13 YP_002348450.1 3976050 R 214092 CDS YP_002348451.1 218930576 1176384 complement(3976792..3977919) 1 NC_003143.1 hypothetical protein 3977919 1176384 YPO3564 Yersinia pestis CO92 hypothetical protein YP_002348451.1 3976792 R 214092 CDS YP_002348452.1 218930577 1176385 3978143..3978547 1 NC_003143.1 cytochrome d ubiquinol oxidase subunit III 3978547 1176385 YPO3565 Yersinia pestis CO92 cytochrome d ubiquinol oxidase subunit III YP_002348452.1 3978143 D 214092 CDS YP_002348453.1 218930578 1176386 3978818..3980191 1 NC_003143.1 protease 3980191 degQ 1176386 degQ Yersinia pestis CO92 protease YP_002348453.1 3978818 D 214092 CDS YP_002348454.1 218930579 1176387 complement(3980308..3980766) 1 NC_003143.1 transposase for the IS1541 insertion element 3980766 tnp 1176387 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348454.1 3980308 R 214092 CDS YP_002348455.1 218930580 1176388 3980992..3982080 1 NC_003143.1 serine endoprotease 3982080 degS 1176388 degS Yersinia pestis CO92 serine endoprotease YP_002348455.1 3980992 D 214092 CDS YP_002348456.1 218930581 1176389 complement(3982261..3983523) 1 NC_003143.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3983523 murA 1176389 murA Yersinia pestis CO92 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002348456.1 3982261 R 214092 CDS YP_002348457.1 218930582 1176390 complement(3983677..3983940) 1 NC_003143.1 BolA-like protein 3983940 1176390 YPO3570 Yersinia pestis CO92 BolA-like protein YP_002348457.1 3983677 R 214092 CDS YP_002348458.1 218930583 1176391 complement(3984078..3984380) 1 NC_003143.1 anti-sigma B factor antagonist 3984380 1176391 YPO3571 Yersinia pestis CO92 anti-sigma B factor antagonist YP_002348458.1 3984078 R 214092 CDS YP_002348459.1 218930584 1176392 complement(3984416..3985039) 1 NC_003143.1 hypothetical protein 3985039 yrbC 1176392 yrbC Yersinia pestis CO92 hypothetical protein YP_002348459.1 3984416 R 214092 CDS YP_002348460.1 218930585 1176393 complement(3985052..3985609) 1 NC_003143.1 hypothetical protein 3985609 yrbD 1176393 yrbD Yersinia pestis CO92 hypothetical protein YP_002348460.1 3985052 R 214092 CDS YP_002348461.1 218930586 1176394 complement(3985614..3986396) 1 NC_003143.1 hypothetical protein 3986396 yrbE 1176394 yrbE Yersinia pestis CO92 hypothetical protein YP_002348461.1 3985614 R 214092 CDS YP_002348462.1 218930587 1176395 complement(3986614..3987432) 1 NC_003143.1 ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein YrbF 3987432 yrbF 1176395 yrbF Yersinia pestis CO92 ABC transporter ATP-binding protein YrbF YP_002348462.1 3986614 R 214092 CDS YP_002348463.1 218930588 1176396 3987697..3988671 1 NC_003143.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3988671 yrbG 1176396 yrbG Yersinia pestis CO92 calcium/sodium:proton antiporter YP_002348463.1 3987697 D 214092 CDS YP_002348464.1 218930589 1176397 3988782..3989768 1 NC_003143.1 D-arabinose 5-phosphate isomerase 3989768 1176397 YPO3577 Yersinia pestis CO92 D-arabinose 5-phosphate isomerase YP_002348464.1 3988782 D 214092 CDS YP_002348465.1 218930590 1176398 3990017..3990580 1 NC_003143.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3990580 1176398 YPO3578 Yersinia pestis CO92 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_002348465.1 3990017 D 214092 CDS YP_002348466.1 218930591 1176399 3990577..3991140 1 NC_003143.1 hypothetical protein 3991140 yrbK 1176399 yrbK Yersinia pestis CO92 hypothetical protein YP_002348466.1 3990577 D 214092 CDS YP_002348467.1 218930592 1176400 3991124..3991669 1 NC_003143.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3991669 1176400 YPO3580 Yersinia pestis CO92 lipopolysaccharide transport periplasmic protein LptA YP_002348467.1 3991124 D 214092 CDS YP_002348468.1 218930593 1176401 3991676..3992401 1 NC_003143.1 ABC transporter ATP-binding protein YhbG 3992401 yhbG 1176401 yhbG Yersinia pestis CO92 ABC transporter ATP-binding protein YhbG YP_002348468.1 3991676 D 214092 CDS YP_002348469.1 218930594 1176402 3992463..3993896 1 NC_003143.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3993896 rpoN 1176402 rpoN Yersinia pestis CO92 RNA polymerase factor sigma-54 YP_002348469.1 3992463 D 214092 CDS YP_002348470.1 218930595 1176404 3994325..3994807 1 NC_003143.1 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3994807 ptsN 1176404 ptsN Yersinia pestis CO92 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_002348470.1 3994325 D 214092 CDS YP_002348471.1 218930596 1176405 3995113..3995967 1 NC_003143.1 hypothetical protein 3995967 1176405 YPO3586 Yersinia pestis CO92 hypothetical protein YP_002348471.1 3995113 D 214092 CDS YP_002348472.1 218930597 1176406 3995964..3996236 1 NC_003143.1 N-regulated PTS system (Npr) phosphohistidinoprotein-hexose phosphotransferase 3996236 ptsO 1176406 ptsO Yersinia pestis CO92 N-regulated PTS system (Npr) phosphohistidinoprotein-hexose phosphotransferase YP_002348472.1 3995964 D 214092 CDS YP_002348473.1 218930598 1176407 3996574..3997509 1 NC_003143.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 3997509 pyrB 1176407 pyrB Yersinia pestis CO92 aspartate carbamoyltransferase YP_002348473.1 3996574 D 214092 CDS YP_002348474.1 218930599 1176408 3997521..3997985 1 NC_003143.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase 3997985 pyrI 1176408 pyrI Yersinia pestis CO92 aspartate carbamoyltransferase YP_002348474.1 3997521 D 214092 CDS YP_002348475.1 218930600 1176409 3998123..3998509 1 NC_003143.1 hypothetical protein 3998509 1176409 YPO3590 Yersinia pestis CO92 hypothetical protein YP_002348475.1 3998123 D 214092 CDS YP_002348476.1 218930601 1176410 3998850..3999872 1 NC_003143.1 transposase for insertion sequence IS100 3999872 y1093 1176410 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002348476.1 3998850 D 214092 CDS YP_002348477.1 218930602 1176411 3999869..4000651 1 NC_003143.1 transposase/IS protein 4000651 1176411 YPO3592 Yersinia pestis CO92 transposase/IS protein YP_002348477.1 3999869 D 214092 CDS YP_002348479.1 218930604 1176414 4001721..4002770 1 NC_003143.1 hypothetical protein 4002770 1176414 YPO3594 Yersinia pestis CO92 hypothetical protein YP_002348479.1 4001721 D 214092 CDS YP_002348480.1 218930605 1176415 4002896..4004212 1 NC_003143.1 hypothetical protein 4004212 1176415 YPO3595 Yersinia pestis CO92 hypothetical protein YP_002348480.1 4002896 D 214092 CDS YP_002348481.1 218930606 1176416 4004212..4004757 1 NC_003143.1 lipoprotein 4004757 1176416 YPO3596 Yersinia pestis CO92 lipoprotein YP_002348481.1 4004212 D 214092 CDS YP_002348482.1 218930607 1176417 4004760..4006106 1 NC_003143.1 hypothetical protein 4006106 1176417 YPO3597 Yersinia pestis CO92 hypothetical protein YP_002348482.1 4004760 D 214092 CDS YP_002348483.1 218930608 1176418 4006106..4006873 1 NC_003143.1 hypothetical protein 4006873 1176418 YPO3598 Yersinia pestis CO92 hypothetical protein YP_002348483.1 4006106 D 214092 CDS YP_002348484.1 218930609 1176419 4006884..4009487 1 NC_003143.1 Clp ATPase 4009487 clpB2 1176419 clpB2 Yersinia pestis CO92 Clp ATPase YP_002348484.1 4006884 D 214092 CDS YP_002348485.1 218930610 1176420 4009484..4010281 1 NC_003143.1 no significant database hits; hypothetical protein 4010281 1176420 YPO3600 Yersinia pestis CO92 hypothetical protein YP_002348485.1 4009484 D 214092 CDS YP_002348486.1 218930611 1176421 4010278..4010964 1 NC_003143.1 hypothetical protein 4010964 1176421 YPO3601 Yersinia pestis CO92 hypothetical protein YP_002348486.1 4010278 D 214092 CDS YP_002348487.1 218930612 1176422 4010961..4012358 1 NC_003143.1 hypothetical protein 4012358 1176422 YPO3602 Yersinia pestis CO92 hypothetical protein YP_002348487.1 4010961 D 214092 CDS YP_002348488.1 218930613 1176423 4012390..4015923 1 NC_003143.1 hypothetical protein 4015923 1176423 YPO3603 Yersinia pestis CO92 hypothetical protein YP_002348488.1 4012390 D 214092 CDS YP_002348491.1 218930616 1176426 4017382..4019784 1 NC_003143.1 Rhs accessory genetic element 4019784 1176426 YPO3606 Yersinia pestis CO92 Rhs accessory genetic element YP_002348491.1 4017382 D 214092 CDS YP_002348492.1 218930617 1176427 4019790..4020248 1 NC_003143.1 hypothetical protein 4020248 1176427 YPO3607 Yersinia pestis CO92 hypothetical protein YP_002348492.1 4019790 D 214092 CDS YP_002348495.1 218930620 1176430 4024505..4024990 1 NC_003143.1 hypothetical protein 4024990 1176430 YPO3610 Yersinia pestis CO92 hypothetical protein YP_002348495.1 4024505 D 214092 CDS YP_002348496.1 218930621 1176431 complement(4025040..4025231) 1 NC_003143.1 no significant database hits; hypothetical protein 4025231 1176431 YPO3611 Yersinia pestis CO92 hypothetical protein YP_002348496.1 4025040 R 214092 CDS YP_008479729.1 537470193 16744776 complement(4025307..4025531) 1 NC_003143.1 hypothetical protein 4025531 16744776 YPO3611a Yersinia pestis CO92 hypothetical protein YP_008479729.1 4025307 R 214092 CDS YP_002348497.1 218930622 1176432 complement(4025613..4026020) 1 NC_003143.1 transcriptional regulator 4026020 1176432 YPO3612 Yersinia pestis CO92 transcriptional regulator YP_002348497.1 4025613 R 214092 CDS YP_002348498.1 218930623 1176433 4026381..4028579 1 NC_003143.1 Rhs accessory genetic element 4028579 1176433 YPO3613 Yersinia pestis CO92 Rhs accessory genetic element YP_002348498.1 4026381 D 214092 CDS YP_002348499.1 218930624 1176434 4028582..4029004 1 NC_003143.1 hypothetical protein 4029004 1176434 YPO3614 Yersinia pestis CO92 hypothetical protein YP_002348499.1 4028582 D 214092 CDS YP_002348500.1 218930625 1176435 4029049..4033587 1 NC_003143.1 hypothetical protein 4033587 1176435 YPO3615 Yersinia pestis CO92 hypothetical protein YP_002348500.1 4029049 D 214092 CDS YP_002348501.1 218930626 1176436 4033596..4034390 1 NC_003143.1 hypothetical protein 4034390 1176436 YPO3616 Yersinia pestis CO92 hypothetical protein YP_002348501.1 4033596 D 214092 CDS YP_002348502.1 218930627 1176437 complement(4034737..4035636) 1 NC_003143.1 no significant database hits; hypothetical protein 4035636 1176437 YPO3617 Yersinia pestis CO92 hypothetical protein YP_002348502.1 4034737 R 214092 CDS YP_002348503.1 218930628 1176438 complement(4035633..4036763) 1 NC_003143.1 oxidoreductase 4036763 1176438 YPO3618 Yersinia pestis CO92 oxidoreductase YP_002348503.1 4035633 R 214092 CDS YP_002348504.1 218930629 1176439 4036958..4037899 1 NC_003143.1 AraC family transcriptional regulator 4037899 1176439 YPO3619 Yersinia pestis CO92 AraC family transcriptional regulator YP_002348504.1 4036958 D 214092 CDS YP_002348505.1 218930630 1176440 complement(4038061..4038564) 1 NC_003143.1 carbohydrate transport protein 4038564 1176440 YPO3620 Yersinia pestis CO92 carbohydrate transport protein YP_002348505.1 4038061 R 214092 CDS YP_002348506.1 218930631 1176441 complement(4038570..4039502) 1 NC_003143.1 carbohydrate kinase 4039502 1176441 YPO3621 Yersinia pestis CO92 carbohydrate kinase YP_002348506.1 4038570 R 214092 CDS YP_002348507.1 218930632 1176442 complement(4039656..4040357) 1 NC_003143.1 deoxyribose-phosphate aldolase 4040357 1176442 YPO3622 Yersinia pestis CO92 deoxyribose-phosphate aldolase YP_002348507.1 4039656 R 214092 CDS YP_002348508.1 218930633 1176443 4040828..4041409 1 NC_003143.1 NAD(P)H-dependent FMN reductase 4041409 ssuE 1176443 ssuE Yersinia pestis CO92 NAD(P)H-dependent FMN reductase YP_002348508.1 4040828 D 214092 CDS YP_002348509.1 218930634 1176444 4041424..4042545 1 NC_003143.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding protein 4042545 ssuA 1176444 ssuA Yersinia pestis CO92 alkanesulfonate transporter substrate-binding protein YP_002348509.1 4041424 D 214092 CDS YP_002348510.1 218930635 1176445 4042564..4043712 1 NC_003143.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 4043712 ssuD 1176445 ssuD Yersinia pestis CO92 alkanesulfonate monooxygenase YP_002348510.1 4042564 D 214092 CDS YP_002348511.1 218930636 1176446 4043721..4044518 1 NC_003143.1 aliphatic sulfonates transporter permease 4044518 ssuC 1176446 ssuC Yersinia pestis CO92 aliphatic sulfonates transporter permease YP_002348511.1 4043721 D 214092 CDS YP_002348512.1 218930637 1176447 4044515..4045330 1 NC_003143.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transporter ATP-binding protein 4045330 ssuB 1176447 ssuB Yersinia pestis CO92 aliphatic sulfonates transporter ATP-binding protein YP_002348512.1 4044515 D 214092 CDS YP_002348514.1 218930639 1176449 4046606..4047961 1 NC_003143.1 xanthine/uracil permease 4047961 yjcD 1176449 yjcD Yersinia pestis CO92 xanthine/uracil permease YP_002348514.1 4046606 D 214092 CDS YP_002348515.1 218930640 1176450 4048310..4049959 1 NC_003143.1 Na(+)/H(+) exchanger protein 4049959 yjcE 1176450 yjcE Yersinia pestis CO92 Na(+)/H(+) exchanger protein YP_002348515.1 4048310 D 214092 CDS YP_002348516.1 218930641 1176451 complement(4050177..4051364) 1 NC_003143.1 no significant database matches; hypothetical protein 4051364 1176451 YPO3631 Yersinia pestis CO92 hypothetical protein YP_002348516.1 4050177 R 214092 CDS YP_002348517.1 218930642 1176452 complement(4051516..4052436) 1 NC_003143.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 4052436 ddg 1176452 ddg Yersinia pestis CO92 lipid A biosynthesis palmitoleoyl acyltransferase YP_002348517.1 4051516 R 214092 CDS YP_002348518.1 218930643 1176453 4053161..4054219 1 NC_003143.1 periplasmic binding protein 4054219 1176453 YPO3633 Yersinia pestis CO92 periplasmic binding protein YP_002348518.1 4053161 D 214092 CDS YP_002348519.1 218930644 1176454 4054423..4055919 1 NC_003143.1 ABC transporter ATP-binding protein 4055919 1176454 YPO3634 Yersinia pestis CO92 ABC transporter ATP-binding protein YP_002348519.1 4054423 D 214092 CDS YP_002348520.1 218930645 1176455 4055912..4056901 1 NC_003143.1 branched-chain amino acid transporter permease 4056901 1176455 YPO3635 Yersinia pestis CO92 branched-chain amino acid transporter permease YP_002348520.1 4055912 D 214092 CDS YP_002348521.1 218930646 1176456 4056903..4057856 1 NC_003143.1 ABC transporter permease 4057856 1176456 YPO3636 Yersinia pestis CO92 ABC transporter permease YP_002348521.1 4056903 D 214092 CDS YP_002348522.1 218930647 1176457 4057875..4059512 1 NC_003143.1 carbohydrate kinase 4059512 1176457 YPO3637 Yersinia pestis CO92 carbohydrate kinase YP_002348522.1 4057875 D 214092 CDS YP_002348523.1 218930648 1176458 4059509..4060114 1 NC_003143.1 phosphosugar isomerase/binding protein 4060114 1176458 YPO3638 Yersinia pestis CO92 phosphosugar isomerase/binding protein YP_002348523.1 4059509 D 214092 CDS YP_002348524.1 218930649 1176459 complement(4060304..4061158) 1 NC_003143.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase YghU 4061158 yghU 1176459 yghU Yersinia pestis CO92 glutathione S-transferase YghU YP_002348524.1 4060304 R 214092 CDS YP_002348525.1 218930650 1176460 4061409..4062755 1 NC_003143.1 hypothetical protein 4062755 1176460 YPO3640 Yersinia pestis CO92 hypothetical protein YP_002348525.1 4061409 D 214092 CDS YP_002348526.1 218930651 1176461 complement(4062862..4064037) 1 NC_003143.1 no significant database hits; hypothetical protein 4064037 1176461 YPO3641 Yersinia pestis CO92 hypothetical protein YP_002348526.1 4062862 R 214092 CDS YP_002348527.1 218930652 1176462 4064442..4064900 1 NC_003143.1 transposase for the IS1541 insertion element 4064900 tnp 1176462 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348527.1 4064442 D 214092 CDS YP_002348528.1 218930653 1176463 complement(4065083..4065295) 1 NC_003143.1 cold-shock protein CspA 4065295 cspa2 1176463 cspa2 Yersinia pestis CO92 cold-shock protein CspA YP_002348528.1 4065083 R 214092 CDS YP_002348529.1 218930654 1176464 complement(4065555..4065767) 1 NC_003143.1 cold-shock protein CspA 4065767 cspa1 1176464 cspa1 Yersinia pestis CO92 cold-shock protein CspA YP_002348529.1 4065555 R 214092 CDS YP_002348531.1 218930656 1176466 complement(4066300..4066767) 1 NC_003143.1 outer membrane lipoprotein 4066767 pcp 1176466 pcp Yersinia pestis CO92 outer membrane lipoprotein YP_002348531.1 4066300 R 214092 CDS YP_002348532.1 218930657 1176467 4067228..4068055 1 NC_003143.1 hypothetical protein 4068055 1176467 YPO3647 Yersinia pestis CO92 hypothetical protein YP_002348532.1 4067228 D 214092 CDS YP_002348533.1 218930658 1176468 4068120..4069010 1 NC_003143.1 2-hydroxy-3-oxopropionate reductase 4069010 1176468 YPO3648 Yersinia pestis CO92 2-hydroxy-3-oxopropionate reductase YP_002348533.1 4068120 D 214092 CDS YP_002348534.1 218930659 1176469 4069188..4069583 1 NC_003143.1 gamma carboxymuconolactone decarboxylase 4069583 1176469 YPO3649 Yersinia pestis CO92 gamma carboxymuconolactone decarboxylase YP_002348534.1 4069188 D 214092 CDS YP_002348535.1 218930660 1176470 4069737..4071101 1 NC_003143.1 metabolite transport protein 4071101 1176470 YPO3650 Yersinia pestis CO92 metabolite transport protein YP_002348535.1 4069737 D 214092 CDS YP_002348536.1 218930661 1176471 4071191..4071853 1 NC_003143.1 GntR family transcriptional regulator 4071853 1176471 YPO3651 Yersinia pestis CO92 GntR family transcriptional regulator YP_002348536.1 4071191 D 214092 CDS YP_002348537.1 218930662 1176472 4071919..4072395 1 NC_003143.1 no significant database hits; hypothetical protein 4072395 1176472 YPO3652 Yersinia pestis CO92 hypothetical protein YP_002348537.1 4071919 D 214092 CDS YP_002348538.1 218930663 1176473 4072626..4072745 1 NC_003143.1 colicin immunity protein 4072745 1176473 YPO3653 Yersinia pestis CO92 colicin immunity protein YP_002348538.1 4072626 D 214092 CDS YP_002348539.1 218930664 1176474 complement(4073149..4073445) 1 NC_003143.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; Fis family transcriptional regulator 4073445 fis 1176474 fis Yersinia pestis CO92 Fis family transcriptional regulator YP_002348539.1 4073149 R 214092 CDS YP_002348540.1 218930665 1176475 complement(4073470..4074435) 1 NC_003143.1 tRNA-dihydrouridine synthase B 4074435 1176475 YPO3655 Yersinia pestis CO92 tRNA-dihydrouridine synthase B YP_002348540.1 4073470 R 214092 CDS YP_002348541.1 218930666 1176476 complement(4075024..4075905) 1 NC_003143.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 4075905 prmA 1176476 prmA Yersinia pestis CO92 ribosomal protein L11 methyltransferase YP_002348541.1 4075024 R 214092 CDS YP_002348542.1 218930667 1176477 complement(4075981..4077435) 1 NC_003143.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 4077435 panF 1176477 panF Yersinia pestis CO92 sodium/panthothenate symporter YP_002348542.1 4075981 R 214092 CDS YP_002348543.1 218930668 1176478 complement(4077425..4077667) 1 NC_003143.1 hypothetical protein 4077667 yhdT 1176478 yhdT Yersinia pestis CO92 hypothetical protein YP_002348543.1 4077425 R 214092 CDS YP_002348544.1 218930669 1176479 complement(4079025..4080374) 1 NC_003143.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 4080374 accC 1176479 accC Yersinia pestis CO92 acetyl-CoA carboxylase biotin carboxylase subunit YP_002348544.1 4079025 R 214092 CDS YP_002348545.1 218930670 1176480 complement(4080386..4080850) 1 NC_003143.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 4080850 accB 1176480 accB Yersinia pestis CO92 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002348545.1 4080386 R 214092 CDS YP_002348546.1 218930671 1176481 complement(4081008..4081460) 1 NC_003143.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 4081460 aroQ 1176481 aroQ Yersinia pestis CO92 3-dehydroquinate dehydratase YP_002348546.1 4081008 R 214092 CDS YP_002348547.1 218930672 1176482 complement(4081723..4082343) 1 NC_003143.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 4082343 1176482 YPO3661 Yersinia pestis CO92 sulfite oxidase subunit YedZ YP_002348547.1 4081723 R 214092 CDS YP_002348548.1 218930673 1176483 complement(4082343..4083443) 1 NC_003143.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 4083443 1176483 YPO3662 Yersinia pestis CO92 sulfite oxidase subunit YedY YP_002348548.1 4082343 R 214092 CDS YP_002348549.1 218930674 1176484 complement(4083666..4084643) 1 NC_003143.1 zinc-binding dehydrogenase 4084643 yhdH 1176484 yhdH Yersinia pestis CO92 zinc-binding dehydrogenase YP_002348549.1 4083666 R 214092 CDS YP_002348550.1 218930675 1176485 4085044..4086960 1 NC_003143.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 4086960 yhdA 1176485 yhdA Yersinia pestis CO92 regulatory protein CsrD YP_002348550.1 4085044 D 214092 CDS YP_002348551.1 218930676 1176486 4087297..4088340 1 NC_003143.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 4088340 envB 1176486 envB Yersinia pestis CO92 rod shape-determining protein MreB YP_002348551.1 4087297 D 214092 CDS YP_002348552.1 218930677 1176487 4088544..4089539 1 NC_003143.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 4089539 mreC 1176487 mreC Yersinia pestis CO92 rod shape-determining protein MreC YP_002348552.1 4088544 D 214092 CDS YP_002348553.1 218930678 1176488 4089536..4090024 1 NC_003143.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 4090024 mreD 1176488 mreD Yersinia pestis CO92 rod shape-determining protein MreD YP_002348553.1 4089536 D 214092 CDS YP_002348554.1 218930679 1176489 4090038..4090631 1 NC_003143.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 4090631 maf 1176489 maf Yersinia pestis CO92 Maf-like protein YP_002348554.1 4090038 D 214092 CDS YP_002348555.1 218930680 1176490 4090621..4092090 1 NC_003143.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 4092090 cafA 1176490 cafA Yersinia pestis CO92 ribonuclease G YP_002348555.1 4090621 D 214092 CDS YP_002348556.1 218930681 1176491 4092184..4096107 1 NC_003143.1 hypothetical protein 4096107 1176491 YPO3670 Yersinia pestis CO92 hypothetical protein YP_002348556.1 4092184 D 214092 CDS YP_002348557.1 218930682 1176492 4096104..4096973 1 NC_003143.1 carbon-nitrogen hydrolase 4096973 1176492 YPO3671 Yersinia pestis CO92 carbon-nitrogen hydrolase YP_002348557.1 4096104 D 214092 CDS YP_002348558.1 218930683 1176493 4096985..4098430 1 NC_003143.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 4098430 tldD 1176493 tldD Yersinia pestis CO92 protease TldD YP_002348558.1 4096985 D 214092 CDS YP_002348559.1 218930684 1176494 complement(4098633..4101491) 1 NC_003143.1 insecticidal toxin 4101491 1176494 YPO3673 Yersinia pestis CO92 insecticidal toxin YP_002348559.1 4098633 R 214092 CDS YP_002348560.1 218930685 1176495 complement(4101516..4104551) 1 NC_003143.1 insecticidal toxin 4104551 1176495 YPO3674 Yersinia pestis CO92 insecticidal toxin YP_002348560.1 4101516 R 214092 CDS YP_002348561.1 218930686 1176496 complement(4104548..4104907) 1 NC_003143.1 no significant database matches; hypothetical protein 4104907 1176496 YPO3675 Yersinia pestis CO92 hypothetical protein YP_002348561.1 4104548 R 214092 CDS YP_002348562.1 218930687 1176497 complement(4104904..4105305) 1 NC_003143.1 hypothetical protein 4105305 1176497 YPO3676 Yersinia pestis CO92 hypothetical protein YP_002348562.1 4104904 R 214092 CDS YP_002348563.1 218930688 1176498 complement(4105318..4105620) 1 NC_003143.1 hypothetical protein 4105620 1176498 YPO3677 Yersinia pestis CO92 hypothetical protein YP_002348563.1 4105318 R 214092 CDS YP_002348564.1 218930689 1176499 complement(4105754..4110244) 1 NC_003143.1 insecticidal toxin complex 4110244 tcaC 1176499 tcaC Yersinia pestis CO92 insecticidal toxin complex YP_002348564.1 4105754 R 214092 CDS YP_002348565.1 218930690 1176501 complement(4113934..4116435) 1 NC_003143.1 insecticial toxin 4116435 1176501 YPO3681 Yersinia pestis CO92 insecticial toxin YP_002348565.1 4113934 R 214092 CDS YP_002348566.1 218930691 1176502 complement(4116671..4117537) 1 NC_003143.1 LysR family transcriptional regulator 4117537 1176502 YPO3682 Yersinia pestis CO92 LysR family transcriptional regulator YP_002348566.1 4116671 R 214092 CDS YP_002348567.1 218930692 1176503 complement(4117798..4118709) 1 NC_003143.1 DNA-binding transcriptional regulator 4118709 1176503 YPO3683 Yersinia pestis CO92 DNA-binding transcriptional regulator YP_002348567.1 4117798 R 214092 CDS YP_002348568.1 218930693 1176504 4119012..4119215 1 NC_003143.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 4119215 1176504 YPO3684 Yersinia pestis CO92 hypothetical protein YP_002348568.1 4119012 D 214092 CDS YP_002348569.1 218930694 1176505 4119223..4120158 1 NC_003143.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 4120158 yhcQ 1176505 yhcQ Yersinia pestis CO92 p-hydroxybenzoic acid efflux subunit AaeA YP_002348569.1 4119223 D 214092 CDS YP_002348570.1 218930695 1176506 4120160..4122115 1 NC_003143.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 4122115 yhcP 1176506 yhcP Yersinia pestis CO92 p-hydroxybenzoic acid efflux subunit AaeB YP_002348570.1 4120160 D 214092 CDS YP_002348571.1 218930696 1176508 4124060..4124518 1 NC_003143.1 ribonuclease 4124518 1176508 YPO3689 Yersinia pestis CO92 ribonuclease YP_002348571.1 4124060 D 214092 CDS YP_002348572.1 218930697 1176509 4124523..4124804 1 NC_003143.1 ribonuclease inhibitor 4124804 1176509 YPO3690 Yersinia pestis CO92 ribonuclease inhibitor YP_002348572.1 4124523 D 214092 CDS YP_002348573.1 218930698 1176510 complement(4124916..4125464) 1 NC_003143.1 hypothetical protein 4125464 1176510 YPO3691 Yersinia pestis CO92 hypothetical protein YP_002348573.1 4124916 R 214092 CDS YP_002348574.1 218930699 1176511 4125645..4126985 1 NC_003143.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4126985 pmbA 1176511 pmbA Yersinia pestis CO92 peptidase PmbA YP_002348574.1 4125645 D 214092 CDS YP_002348575.1 218930700 1176512 4127240..4127878 1 NC_003143.1 hypothetical protein 4127878 1176512 YPO3693 Yersinia pestis CO92 hypothetical protein YP_002348575.1 4127240 D 214092 CDS YP_002348576.1 218930701 1176513 4128086..4128472 1 NC_003143.1 cytochrome 4128472 1176513 YPO3694 Yersinia pestis CO92 cytochrome YP_002348576.1 4128086 D 214092 CDS YP_002348577.1 218930702 1176514 complement(4128696..4129106) 1 NC_003143.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 4129106 rnk 1176514 rnk Yersinia pestis CO92 nucleoside diphosphate kinase regulator YP_002348577.1 4128696 R 214092 CDS YP_002348578.1 218930703 1176515 complement(4129459..4131126) 1 NC_003143.1 trehalose-6-phosphate hydrolase 4131126 treC 1176515 treC Yersinia pestis CO92 trehalose-6-phosphate hydrolase YP_002348578.1 4129459 R 214092 CDS YP_002348579.1 218930704 1176516 complement(4131221..4132636) 1 NC_003143.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunits IIBC 4132636 treB 1176516 treB Yersinia pestis CO92 PTS system trehalose(maltose)-specific transporter subunits IIBC YP_002348579.1 4131221 R 214092 CDS YP_002348580.1 218930705 1176517 complement(4133047..4134000) 1 NC_003143.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 4134000 treR 1176517 treR Yersinia pestis CO92 trehalose repressor YP_002348580.1 4133047 R 214092 CDS YP_002348581.1 218930706 1176518 complement(4134234..4134710) 1 NC_003143.1 no significant database matches; hypothetical protein 4134710 1176518 YPO3699 Yersinia pestis CO92 hypothetical protein YP_002348581.1 4134234 R 214092 CDS YP_002348582.1 218930707 1176519 complement(4134826..4135608) 1 NC_003143.1 transposase/IS protein 4135608 1176519 YPO3700 Yersinia pestis CO92 transposase/IS protein YP_002348582.1 4134826 R 214092 CDS YP_002348583.1 218930708 1176520 complement(4135605..4136627) 1 NC_003143.1 transposase for insertion sequence IS100 4136627 y1093 1176520 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002348583.1 4135605 R 214092 CDS YP_002348585.1 218930710 1176522 4137082..4137867 1 NC_003143.1 transposase for insertion sequence IS1661 4137867 1176522 YPO3703 Yersinia pestis CO92 transposase for insertion sequence IS1661 YP_002348585.1 4137082 D 214092 CDS YP_002348586.1 218930711 1176524 complement(4138983..4139423) 1 NC_003143.1 hypothetical protein 4139423 1176524 YPO3705 Yersinia pestis CO92 hypothetical protein YP_002348586.1 4138983 R 214092 CDS YP_002348587.1 218930712 1176525 complement(4139430..4140911) 1 NC_003143.1 hypothetical protein 4140911 1176525 YPO3706 Yersinia pestis CO92 hypothetical protein YP_002348587.1 4139430 R 214092 CDS YP_002348588.1 218930713 1176526 complement(4140979..4141476) 1 NC_003143.1 hypothetical protein 4141476 1176526 YPO3707 Yersinia pestis CO92 hypothetical protein YP_002348588.1 4140979 R 214092 CDS YP_002348589.1 218930714 1176527 4142000..4142518 1 NC_003143.1 hypothetical protein 4142518 1176527 YPO3708 Yersinia pestis CO92 hypothetical protein YP_002348589.1 4142000 D 214092 CDS YP_002348590.1 218930715 1176528 complement(4142670..4143008) 1 NC_003143.1 no significant database hits; hypothetical protein 4143008 1176528 YPO3709 Yersinia pestis CO92 hypothetical protein YP_002348590.1 4142670 R 214092 CDS YP_002348591.1 218930716 1176529 complement(4143419..4144348) 1 NC_003143.1 maltose regulon periplasmic protein 4144348 malM 1176529 malM Yersinia pestis CO92 maltose regulon periplasmic protein YP_002348591.1 4143419 R 214092 CDS YP_002348592.1 218930717 1176530 complement(4144571..4145842) 1 NC_003143.1 porin involved in the transport of maltose and maltodextrins; maltoporin 4145842 lamB 1176530 lamB Yersinia pestis CO92 maltoporin YP_002348592.1 4144571 R 214092 CDS YP_002348593.1 218930718 1176531 complement(4145913..4147022) 1 NC_003143.1 with malEFG is involved in import of maltose/maltodextrin; maltose ABC transporter ATP-binding protein 4147022 malK 1176531 malK Yersinia pestis CO92 maltose ABC transporter ATP-binding protein YP_002348593.1 4145913 R 214092 CDS YP_002348594.1 218930719 1176532 complement(4147026..4147262) 1 NC_003143.1 no significant database hits; hypothetical protein 4147262 1176532 YPO3713 Yersinia pestis CO92 hypothetical protein YP_002348594.1 4147026 R 214092 CDS YP_002348595.1 218930720 1176533 4147824..4149035 1 NC_003143.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter substrate-binding protein 4149035 malE 1176533 malE Yersinia pestis CO92 maltose ABC transporter substrate-binding protein YP_002348595.1 4147824 D 214092 CDS YP_002348596.1 218930721 1176534 4149222..4150799 1 NC_003143.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4150799 malF 1176534 malF Yersinia pestis CO92 maltose transporter membrane protein YP_002348596.1 4149222 D 214092 CDS YP_002348597.1 218930722 1176535 4150813..4151703 1 NC_003143.1 with MalKFE is involved in the transport of maltose into the cell; maltose ABC transporter permease 4151703 malG 1176535 malG Yersinia pestis CO92 maltose ABC transporter permease YP_002348597.1 4150813 D 214092 CDS YP_002348598.1 218930723 1176536 complement(4151846..4152253) 1 NC_003143.1 phosphate-starvation-inducible protein PsiE 4152253 yjbA 1176536 yjbA Yersinia pestis CO92 phosphate-starvation-inducible protein PsiE YP_002348598.1 4151846 R 214092 CDS YP_002348599.1 218930724 1176537 complement(4152388..4154034) 1 NC_003143.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4154034 pgi 1176537 pgi Yersinia pestis CO92 glucose-6-phosphate isomerase YP_002348599.1 4152388 R 214092 CDS YP_002348600.1 218930725 1176538 4154404..4155789 1 NC_003143.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase 4155789 lysC 1176538 lysC Yersinia pestis CO92 aspartate kinase YP_002348600.1 4154404 D 214092 CDS YP_002348601.1 218930726 1176539 4156357..4158042 1 NC_003143.1 hemolysin activator protein 4158042 hpmB 1176539 hpmB Yersinia pestis CO92 hemolysin activator protein YP_002348601.1 4156357 D 214092 CDS YP_002348602.1 218930727 1176540 4158112..4163019 1 NC_003143.1 hemolysin 4163019 1176540 YPO3721 Yersinia pestis CO92 hemolysin YP_002348602.1 4158112 D 214092 CDS YP_002348603.1 218930728 1176541 complement(4163115..4166810) 1 NC_003143.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4166810 metH 1176541 metH Yersinia pestis CO92 B12-dependent methionine synthase YP_002348603.1 4163115 R 214092 CDS YP_002348604.1 218930729 1176543 complement(4167989..4169716) 1 NC_003143.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase protein 4169716 aceK 1176543 aceK Yersinia pestis CO92 bifunctional isocitrate dehydrogenase kinase/phosphatase protein YP_002348604.1 4167989 R 214092 CDS YP_002348605.1 218930730 1176544 complement(4169972..4171279) 1 NC_003143.1 isocitrate lyase 4171279 aceA 1176544 aceA Yersinia pestis CO92 isocitrate lyase YP_002348605.1 4169972 R 214092 CDS YP_002348606.1 218930731 1176545 complement(4171326..4172924) 1 NC_003143.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4172924 aceB 1176545 aceB Yersinia pestis CO92 malate synthase YP_002348606.1 4171326 R 214092 CDS YP_002348607.1 218930732 1176546 complement(4173345..4174274) 1 NC_003143.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4174274 metA 1176546 metA Yersinia pestis CO92 homoserine O-succinyltransferase YP_002348607.1 4173345 R 214092 CDS YP_008479730.1 537470194 16744779 4180465..4180650 1 NC_003143.1 hypothetical protein 4180650 16744779 YPO3728a Yersinia pestis CO92 hypothetical protein YP_008479730.1 4180465 D 214092 CDS YP_002348608.1 218930733 1176554 4181118..4182707 1 NC_003143.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4182707 purH 1176554 purH Yersinia pestis CO92 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002348608.1 4181118 D 214092 CDS YP_002348609.1 218930734 1176555 4182767..4184053 1 NC_003143.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 4184053 purD 1176555 purD Yersinia pestis CO92 phosphoribosylamine--glycine ligase YP_002348609.1 4182767 D 214092 CDS YP_002348610.1 218930735 1176556 complement(4184201..4184902) 1 NC_003143.1 hypothetical protein 4184902 yjaH 1176556 yjaH Yersinia pestis CO92 hypothetical protein YP_002348610.1 4184201 R 214092 CDS YP_002348611.1 218930736 1176557 complement(4184904..4185179) 1 NC_003143.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 4185179 hupA 1176557 hupA Yersinia pestis CO92 transcriptional regulator HU subunit alpha YP_002348611.1 4184904 R 214092 CDS YP_002348612.1 218930737 1176558 complement(4185368..4185958) 1 NC_003143.1 hypothetical protein 4185958 1176558 YPO3732 Yersinia pestis CO92 hypothetical protein YP_002348612.1 4185368 R 214092 CDS YP_002348613.1 218930738 1176559 complement(4186004..4186708) 1 NC_003143.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 4186708 nfi 1176559 nfi Yersinia pestis CO92 endonuclease V YP_002348613.1 4186004 R 214092 CDS YP_002348614.1 218930739 1176560 complement(4186774..4187841) 1 NC_003143.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 4187841 hemE 1176560 hemE Yersinia pestis CO92 uroporphyrinogen decarboxylase YP_002348614.1 4186774 R 214092 CDS YP_002348615.1 218930740 1176561 complement(4187960..4188745) 1 NC_003143.1 no significant database hits; hypothetical protein 4188745 1176561 YPO3735 Yersinia pestis CO92 hypothetical protein YP_002348615.1 4187960 R 214092 CDS YP_002348616.1 218930741 1176562 complement(4188838..4189620) 1 NC_003143.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 4189620 nudC 1176562 nudC Yersinia pestis CO92 NADH pyrophosphatase YP_002348616.1 4188838 R 214092 CDS YP_002348617.1 218930742 1176563 4189717..4190226 1 NC_003143.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 4190226 rsd 1176563 rsd Yersinia pestis CO92 anti-RNA polymerase sigma 70 factor YP_002348617.1 4189717 D 214092 CDS YP_002348618.1 218930743 1176564 4190349..4190609 1 NC_003143.1 no significant database hits; hypothetical protein 4190609 1176564 YPO3738 Yersinia pestis CO92 hypothetical protein YP_002348618.1 4190349 D 214092 CDS YP_002348619.1 218930744 1176565 4190602..4192647 1 NC_003143.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 4192647 thiC 1176565 thiC Yersinia pestis CO92 thiamine biosynthesis protein ThiC YP_002348619.1 4190602 D 214092 CDS YP_002348620.1 218930745 1176566 4192661..4193308 1 NC_003143.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 4193308 thiE 1176566 thiE Yersinia pestis CO92 thiamine-phosphate pyrophosphorylase YP_002348620.1 4192661 D 214092 CDS YP_002348621.1 218930746 1176567 4193298..4194095 1 NC_003143.1 thiamine biosynthesis protein ThiF 4194095 thiF 1176567 thiF Yersinia pestis CO92 thiamine biosynthesis protein ThiF YP_002348621.1 4193298 D 214092 CDS YP_008853948.1 559797723 17699571 4194116..4194307 1 NC_003143.1 sulfur carrier protein ThiS 4194307 17699571 YPO3741a Yersinia pestis CO92 sulfur carrier protein ThiS YP_008853948.1 4194116 D 214092 CDS YP_002348622.1 218930747 1176568 4194309..4195124 1 NC_003143.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 4195124 thiG 1176568 thiG Yersinia pestis CO92 thiazole synthase YP_002348622.1 4194309 D 214092 CDS YP_002348623.1 218930748 1176569 4195117..4196247 1 NC_003143.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 4196247 thiH 1176569 thiH Yersinia pestis CO92 thiamine biosynthesis protein ThiH YP_002348623.1 4195117 D 214092 CDS YP_002348624.1 218930749 1176570 complement(4196290..4196403) 1 NC_003143.1 no significant database hits; hypothetical protein 4196403 1176570 YPO3744 Yersinia pestis CO92 hypothetical protein YP_002348624.1 4196290 R 214092 CDS YP_002348625.1 218930750 1176571 4196679..4197137 1 NC_003143.1 transposase for the IS1541 insertion element 4197137 tnp 1176571 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348625.1 4196679 D 214092 CDS YP_002348626.1 218930751 1176572 complement(4197264..4201484) 1 NC_003143.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 4201484 rpoC 1176572 rpoC Yersinia pestis CO92 DNA-directed RNA polymerase subunit beta' YP_002348626.1 4197264 R 214092 CDS YP_002348627.1 218930752 1176573 complement(4201613..4205641) 1 NC_003143.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 4205641 rpoB 1176573 rpoB Yersinia pestis CO92 DNA-directed RNA polymerase subunit beta YP_002348627.1 4201613 R 214092 CDS YP_002348628.1 218930753 1176574 complement(4205984..4206352) 1 NC_003143.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 4206352 rplL 1176574 rplL Yersinia pestis CO92 50S ribosomal protein L7/L12 YP_002348628.1 4205984 R 214092 CDS YP_002348629.1 218930754 1176575 complement(4206419..4206916) 1 NC_003143.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 4206916 rplJ 1176575 rplJ Yersinia pestis CO92 50S ribosomal protein L10 YP_002348629.1 4206419 R 214092 CDS YP_002348630.1 218930755 1176576 complement(4207281..4207985) 1 NC_003143.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 4207985 rplA 1176576 rplA Yersinia pestis CO92 50S ribosomal protein L1 YP_002348630.1 4207281 R 214092 CDS YP_002348631.1 218930756 1176577 complement(4207989..4208417) 1 NC_003143.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 4208417 rplK 1176577 rplK Yersinia pestis CO92 50S ribosomal protein L11 YP_002348631.1 4207989 R 214092 CDS YP_002348632.1 218930757 1176578 complement(4208608..4209153) 1 NC_003143.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 4209153 nusG 1176578 nusG Yersinia pestis CO92 transcription antitermination protein NusG YP_002348632.1 4208608 R 214092 CDS YP_002348633.1 218930758 1176579 complement(4209155..4209538) 1 NC_003143.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 4209538 secE 1176579 secE Yersinia pestis CO92 preprotein translocase subunit SecE YP_002348633.1 4209155 R 214092 CDS YP_002348634.1 218930759 1176580 complement(4209789..4210973) 1 NC_003143.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 4210973 tuf 1176580 tuf Yersinia pestis CO92 elongation factor Tu YP_002348634.1 4209789 R 214092 CDS YP_002348635.1 218930760 1176585 complement(4212030..4212812) 1 NC_003143.1 transposase/IS protein 4212812 1176585 YPO3755 Yersinia pestis CO92 transposase/IS protein YP_002348635.1 4212030 R 214092 CDS YP_002348636.1 218930761 1176586 complement(4212809..4213831) 1 NC_003143.1 transposase for insertion sequence IS100 4213831 y1093 1176586 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002348636.1 4212809 R 214092 CDS YP_002348637.1 218930762 1176587 4213921..4214472 1 NC_003143.1 acetyltransferase 4214472 1176587 YPO3757 Yersinia pestis CO92 acetyltransferase YP_002348637.1 4213921 D 214092 CDS YP_002348638.1 218930763 1176588 4214683..4215633 1 NC_003143.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 4215633 coaA 1176588 coaA Yersinia pestis CO92 pantothenate kinase YP_002348638.1 4214683 D 214092 CDS YP_002348639.1 218930764 1176589 complement(4215668..4216627) 1 NC_003143.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 4216627 birA 1176589 birA Yersinia pestis CO92 biotin--protein ligase YP_002348639.1 4215668 R 214092 CDS YP_002348640.1 218930765 1176590 complement(4216624..4217661) 1 NC_003143.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 4217661 murB 1176590 murB Yersinia pestis CO92 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002348640.1 4216624 R 214092 CDS YP_008479731.1 537470195 16744780 4223329..4223514 1 NC_003143.1 hypothetical protein 4223514 16744780 YPO3760a Yersinia pestis CO92 hypothetical protein YP_008479731.1 4223329 D 214092 CDS YP_002348641.1 218930766 1176596 complement(4223798..4224331) 1 NC_003143.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 4224331 hemG 1176596 hemG Yersinia pestis CO92 protoporphyrinogen oxidase YP_002348641.1 4223798 R 214092 CDS YP_002348642.1 218930767 1176597 complement(4224353..4225804) 1 NC_003143.1 potassium transporter 4225804 trkH 1176597 trkH Yersinia pestis CO92 potassium transporter YP_002348642.1 4224353 R 214092 CDS YP_008479732.1 537470196 16744781 complement(4225844..4226320) 1 NC_003143.1 hypothetical protein 4226320 16744781 YPO3764a Yersinia pestis CO92 hypothetical protein YP_008479732.1 4225844 R 214092 CDS YP_002348643.1 218930768 1176599 complement(4226393..4226851) 1 NC_003143.1 transposase for the IS1541 insertion element 4226851 tnp 1176599 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348643.1 4226393 R 214092 CDS YP_002348644.1 218930769 1176600 complement(4227165..4228496) 1 NC_003143.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 4228496 pepQ 1176600 pepQ Yersinia pestis CO92 proline dipeptidase YP_002348644.1 4227165 R 214092 CDS YP_002348645.1 218930770 1176601 4228823..4231012 1 NC_003143.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 4231012 fadB 1176601 fadB Yersinia pestis CO92 multifunctional fatty acid oxidation complex subunit alpha YP_002348645.1 4228823 D 214092 CDS YP_002348646.1 218930771 1176602 4231024..4232187 1 NC_003143.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 4232187 fadA 1176602 fadA Yersinia pestis CO92 3-ketoacyl-CoA thiolase YP_002348646.1 4231024 D 214092 CDS YP_002348647.1 218930772 1176603 complement(4232347..4233048) 1 NC_003143.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 4233048 fre 1176603 fre Yersinia pestis CO92 FMN reductase YP_002348647.1 4232347 R 214092 CDS YP_002348648.1 218930773 1176604 complement(4233103..4234599) 1 NC_003143.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 4234599 1176604 YPO3769 Yersinia pestis CO92 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002348648.1 4233103 R 214092 CDS YP_002348649.1 218930774 1176605 4234847..4235335 1 NC_003143.1 transcriptional activator RfaH 4235335 rfaH 1176605 rfaH Yersinia pestis CO92 transcriptional activator RfaH YP_002348649.1 4234847 D 214092 CDS YP_002348650.1 218930775 1176606 complement(4235445..4236467) 1 NC_003143.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 4236467 hemB 1176606 hemB Yersinia pestis CO92 delta-aminolevulinic acid dehydratase YP_002348650.1 4235445 R 214092 CDS YP_002348651.1 218930776 1176608 complement(4236856..4237638) 1 NC_003143.1 transposase/IS protein 4237638 1176608 YPO3773 Yersinia pestis CO92 transposase/IS protein YP_002348651.1 4236856 R 214092 CDS YP_002348652.1 218930777 1176609 complement(4237635..4238657) 1 NC_003143.1 transposase for insertion sequence IS100 4238657 y1093 1176609 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002348652.1 4237635 R 214092 CDS YP_002348653.1 218930778 1176610 complement(4239279..4240055) 1 NC_003143.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 4240055 tatC 1176610 tatC Yersinia pestis CO92 twin-arginine protein translocation system subunit TatC YP_002348653.1 4239279 R 214092 CDS YP_002348654.1 218930779 1176611 complement(4240058..4240720) 1 NC_003143.1 Sec-independent protein translocase protein TatB 4240720 mtta2 1176611 mtta2 Yersinia pestis CO92 Sec-independent protein translocase protein TatB YP_002348654.1 4240058 R 214092 CDS YP_002348655.1 218930780 1176612 complement(4240724..4240990) 1 NC_003143.1 Sec-independent protein translocase protein TatA 4240990 1176612 YPO3778 Yersinia pestis CO92 Sec-independent protein translocase protein TatA YP_002348655.1 4240724 R 214092 CDS YP_002348656.1 218930781 1176613 complement(4241170..4242801) 1 NC_003143.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 4242801 ubiB 1176613 ubiB Yersinia pestis CO92 ubiquinone biosynthesis protein UbiB YP_002348656.1 4241170 R 214092 CDS YP_002348657.1 218930782 1176614 complement(4242801..4243433) 1 NC_003143.1 hypothetical protein 4243433 1176614 YPO3780 Yersinia pestis CO92 hypothetical protein YP_002348657.1 4242801 R 214092 CDS YP_002348658.1 218930783 1176615 complement(4243465..4244220) 1 NC_003143.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 4244220 ubiE 1176615 ubiE Yersinia pestis CO92 ubiquinone/menaquinone biosynthesis methyltransferase YP_002348658.1 4243465 R 214092 CDS YP_002348659.1 218930784 1176616 complement(4244312..4245745) 1 NC_003143.1 DNA recombination protein 4245745 rumC 1176616 rumC Yersinia pestis CO92 DNA recombination protein YP_002348659.1 4244312 R 214092 CDS YP_002348660.1 218930785 1176617 complement(4246025..4246555) 1 NC_003143.1 hypothetical protein 4246555 1176617 YPO3783 Yersinia pestis CO92 hypothetical protein YP_002348660.1 4246025 R 214092 CDS YP_002348661.1 218930786 1176618 complement(4246827..4248644) 1 NC_003143.1 carbon starvation protein 4248644 1176618 YPO3784 Yersinia pestis CO92 carbon starvation protein YP_002348661.1 4246827 R 214092 CDS YP_002348662.1 218930787 1176619 complement(4249002..4249832) 1 NC_003143.1 hypothetical protein 4249832 1176619 YPO3785 Yersinia pestis CO92 hypothetical protein YP_002348662.1 4249002 R 214092 CDS YP_002348663.1 218930788 1176620 complement(4249953..4250714) 1 NC_003143.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 4250714 udp 1176620 udp Yersinia pestis CO92 uridine phosphorylase YP_002348663.1 4249953 R 214092 CDS YP_002348664.1 218930789 1176621 4251211..4252014 1 NC_003143.1 carboxymethylenebutenolidase 4252014 1176621 YPO3787 Yersinia pestis CO92 carboxymethylenebutenolidase YP_002348664.1 4251211 D 214092 CDS YP_002348665.1 218930790 1176622 complement(4252069..4254345) 1 NC_003143.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 4254345 metE 1176622 metE Yersinia pestis CO92 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase YP_002348665.1 4252069 R 214092 CDS YP_002348666.1 218930791 1176623 4254451..4255404 1 NC_003143.1 LysR family transcriptional regulator 4255404 metR 1176623 metR Yersinia pestis CO92 LysR family transcriptional regulator YP_002348666.1 4254451 D 214092 CDS YP_002348667.1 218930792 1176624 complement(4255292..4256191) 1 NC_003143.1 hypothetical protein 4256191 yigM 1176624 yigM Yersinia pestis CO92 hypothetical protein YP_002348667.1 4255292 R 214092 CDS YP_002348668.1 218930793 1176625 complement(4256573..4257499) 1 NC_003143.1 hypothetical protein 4257499 1176625 YPO3791 Yersinia pestis CO92 hypothetical protein YP_002348668.1 4256573 R 214092 CDS YP_002348669.1 218930794 1176626 complement(4257600..4258349) 1 NC_003143.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; cytoplasmic glycerophosphodiester phosphodiesterase 4258349 ugpQ 1176626 ugpQ Yersinia pestis CO92 cytoplasmic glycerophosphodiester phosphodiesterase YP_002348669.1 4257600 R 214092 CDS YP_002348670.1 218930795 1176627 complement(4258346..4259419) 1 NC_003143.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding protein 4259419 ugpC 1176627 ugpC Yersinia pestis CO92 glycerol-3-phosphate transporter ATP-binding protein YP_002348670.1 4258346 R 214092 CDS YP_002348671.1 218930796 1176628 complement(4259426..4260271) 1 NC_003143.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 4260271 ugpE 1176628 ugpE Yersinia pestis CO92 glycerol-3-phosphate transporter membrane protein YP_002348671.1 4259426 R 214092 CDS YP_002348672.1 218930797 1176629 complement(4260268..4261155) 1 NC_003143.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 4261155 ugpA 1176629 ugpA Yersinia pestis CO92 glycerol-3-phosphate transporter permease YP_002348672.1 4260268 R 214092 CDS YP_002348673.1 218930798 1176630 complement(4261453..4262772) 1 NC_003143.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter substrate-binding protein 4262772 ugpB 1176630 ugpB Yersinia pestis CO92 glycerol-3-phosphate transporter substrate-binding protein YP_002348673.1 4261453 R 214092 CDS YP_002348674.1 218930799 1176631 4263327..4263818 1 NC_003143.1 hypothetical protein 4263818 1176631 YPO3797 Yersinia pestis CO92 hypothetical protein YP_002348674.1 4263327 D 214092 CDS YP_002348675.1 218930800 1176632 4264085..4266418 1 NC_003143.1 hypothetical protein 4266418 1176632 YPO3798 Yersinia pestis CO92 hypothetical protein YP_002348675.1 4264085 D 214092 CDS YP_002348676.1 218930801 1176633 4266436..4267122 1 NC_003143.1 hypothetical protein 4267122 1176633 YPO3799 Yersinia pestis CO92 hypothetical protein YP_002348676.1 4266436 D 214092 CDS YP_002348677.1 218930802 1176634 4267094..4267741 1 NC_003143.1 hypothetical protein 4267741 1176634 YPO3800 Yersinia pestis CO92 hypothetical protein YP_002348677.1 4267094 D 214092 CDS YP_002348678.1 218930803 1176635 4267803..4268321 1 NC_003143.1 hypothetical protein 4268321 1176635 YPO3801 Yersinia pestis CO92 hypothetical protein YP_002348678.1 4267803 D 214092 CDS YP_002348679.1 218930804 1176636 4268434..4269540 1 NC_003143.1 no significant database matches; hypothetical protein 4269540 1176636 YPO3802 Yersinia pestis CO92 hypothetical protein YP_002348679.1 4268434 D 214092 CDS YP_002348680.1 218930805 1176637 complement(4269655..4270116) 1 NC_003143.1 no significant database hits; hypothetical protein 4270116 1176637 YPO3803 Yersinia pestis CO92 hypothetical protein YP_002348680.1 4269655 R 214092 CDS YP_002348681.1 218930806 1176638 complement(4270344..4271045) 1 NC_003143.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding protein 4271045 livF 1176638 livF Yersinia pestis CO92 leucine/isoleucine/valine transporter ATP-binding protein YP_002348681.1 4270344 R 214092 CDS YP_002348682.1 218930807 1176639 complement(4271090..4271857) 1 NC_003143.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding protein 4271857 livG 1176639 livG Yersinia pestis CO92 leucine/isoleucine/valine transporter ATP-binding protein YP_002348682.1 4271090 R 214092 CDS YP_002348683.1 218930808 1176640 complement(4271854..4273140) 1 NC_003143.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease 4273140 livM 1176640 livM Yersinia pestis CO92 leucine/isoleucine/valine transporter permease YP_002348683.1 4271854 R 214092 CDS YP_002348684.1 218930809 1176641 complement(4273137..4274063) 1 NC_003143.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease LivH 4274063 livH 1176641 livH Yersinia pestis CO92 branched-chain amino acid transporter permease LivH YP_002348684.1 4273137 R 214092 CDS YP_002348685.1 218930810 1176642 complement(4274244..4275359) 1 NC_003143.1 branched-chain amino acid-binding protein 4275359 livJ 1176642 livJ Yersinia pestis CO92 branched-chain amino acid-binding protein YP_002348685.1 4274244 R 214092 CDS YP_002348686.1 218930811 1176643 4275781..4276173 1 NC_003143.1 acetyltransferase 4276173 yhhK 1176643 yhhK Yersinia pestis CO92 acetyltransferase YP_002348686.1 4275781 D 214092 CDS YP_002348687.1 218930812 1176644 complement(4276419..4276877) 1 NC_003143.1 transposase for the IS1541 insertion element 4276877 tnp 1176644 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348687.1 4276419 R 214092 CDS YP_002348688.1 218930813 1176645 complement(4277091..4277948) 1 NC_003143.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 4277948 rpoH 1176645 rpoH Yersinia pestis CO92 RNA polymerase factor sigma-32 YP_002348688.1 4277091 R 214092 CDS YP_002348689.1 218930814 1176646 complement(4278259..4279212) 1 NC_003143.1 ABC transporter, membrane protein; cell division protein FtsX 4279212 ftsX 1176646 ftsX Yersinia pestis CO92 cell division protein FtsX YP_002348689.1 4278259 R 214092 CDS YP_002348690.1 218930815 1176647 complement(4279202..4279870) 1 NC_003143.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 4279870 ftsE 1176647 ftsE Yersinia pestis CO92 cell division protein FtsE YP_002348690.1 4279202 R 214092 CDS YP_002348691.1 218930816 1176648 complement(4279876..4281501) 1 NC_003143.1 cell division protein 4281501 ftsY 1176648 ftsY Yersinia pestis CO92 cell division protein YP_002348691.1 4279876 R 214092 CDS YP_002348692.1 218930817 1176649 4281530..4281673 1 NC_003143.1 no significant database hits; hypothetical protein 4281673 1176649 YPO3815 Yersinia pestis CO92 hypothetical protein YP_002348692.1 4281530 D 214092 CDS YP_002348693.1 218930818 1176650 4281783..4282445 1 NC_003143.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 4282445 rsmD 1176650 rsmD Yersinia pestis CO92 16S rRNA m(2)G966-methyltransferase YP_002348693.1 4281783 D 214092 CDS YP_002348694.1 218930819 1176651 4282435..4282707 1 NC_003143.1 hypothetical protein 4282707 yhhL 1176651 yhhL Yersinia pestis CO92 hypothetical protein YP_002348694.1 4282435 D 214092 CDS YP_002348695.1 218930820 1176652 complement(4282894..4283313) 1 NC_003143.1 hypothetical protein 4283313 1176652 YPO3817 Yersinia pestis CO92 hypothetical protein YP_002348695.1 4282894 R 214092 CDS YP_002348696.1 218930821 1176653 complement(4283525..4283845) 1 NC_003143.1 hypothetical protein 4283845 1176653 YPO3818 Yersinia pestis CO92 hypothetical protein YP_002348696.1 4283525 R 214092 CDS YP_002348697.1 218930822 1176654 4284135..4284761 1 NC_003143.1 hypothetical protein 4284761 yhhN 1176654 yhhN Yersinia pestis CO92 hypothetical protein YP_002348697.1 4284135 D 214092 CDS YP_002348698.1 218930823 1176655 4285175..4287541 1 NC_003143.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 4287541 zntA 1176655 zntA Yersinia pestis CO92 zinc/cadmium/mercury/lead-transporting ATPase YP_002348698.1 4285175 D 214092 CDS YP_002348699.1 218930824 1176656 complement(4287625..4287879) 1 NC_003143.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 4287879 1176656 YPO3821 Yersinia pestis CO92 sulfur transfer protein SirA YP_002348699.1 4287625 R 214092 CDS YP_002348700.1 218930825 1176657 4288163..4288831 1 NC_003143.1 hypothetical protein 4288831 yhhQ 1176657 yhhQ Yersinia pestis CO92 hypothetical protein YP_002348700.1 4288163 D 214092 CDS YP_002348701.1 218930826 1176658 4288961..4289488 1 NC_003143.1 hypothetical protein 4289488 dcrB 1176658 dcrB Yersinia pestis CO92 hypothetical protein YP_002348701.1 4288961 D 214092 CDS YP_002348702.1 218930827 1176659 complement(4289650..4290945) 1 NC_003143.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 4290945 glpC 1176659 glpC Yersinia pestis CO92 sn-glycerol-3-phosphate dehydrogenase subunit C YP_002348702.1 4289650 R 214092 CDS YP_002348703.1 218930828 1176660 complement(4290942..4292216) 1 NC_003143.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 4292216 glpB 1176660 glpB Yersinia pestis CO92 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_002348703.1 4290942 R 214092 CDS YP_002348704.1 218930829 1176661 complement(4292206..4293861) 1 NC_003143.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 4293861 glpA 1176661 glpA Yersinia pestis CO92 sn-glycerol-3-phosphate dehydrogenase subunit A YP_002348704.1 4292206 R 214092 CDS YP_002348705.1 218930830 1176662 4294486..4295601 1 NC_003143.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 4295601 glpQ 1176662 glpQ Yersinia pestis CO92 glycerophosphodiester phosphodiesterase YP_002348705.1 4294486 D 214092 CDS YP_002348706.1 218930831 1176663 complement(4295675..4296727) 1 NC_003143.1 no significant database hits; hypothetical protein 4296727 1176663 YPO3828 Yersinia pestis CO92 hypothetical protein YP_002348706.1 4295675 R 214092 CDS YP_002348707.1 218930832 1176664 complement(4297143..4297952) 1 NC_003143.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 4297952 1176664 YPO3829 Yersinia pestis CO92 sugar phosphatase YP_002348707.1 4297143 R 214092 CDS YP_002348708.1 218930833 1176665 complement(4297987..4299000) 1 NC_003143.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 4299000 pldB 1176665 pldB Yersinia pestis CO92 lysophospholipase L2 YP_002348708.1 4297987 R 214092 CDS YP_002348709.1 218930834 1176666 4299196..4299816 1 NC_003143.1 homoserine/homoserine lactone efflux protein 4299816 rhtB 1176666 rhtB Yersinia pestis CO92 homoserine/homoserine lactone efflux protein YP_002348709.1 4299196 D 214092 CDS YP_002348710.1 218930835 1176667 complement(4299867..4300487) 1 NC_003143.1 threonine efflux system 4300487 rhtC 1176667 rhtC Yersinia pestis CO92 threonine efflux system YP_002348710.1 4299867 R 214092 CDS YP_002348711.1 218930836 1176668 complement(4300594..4302426) 1 NC_003143.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 4302426 recQ 1176668 recQ Yersinia pestis CO92 ATP-dependent DNA helicase RecQ YP_002348711.1 4300594 R 214092 CDS YP_002348712.1 218930837 1176669 complement(4302504..4303382) 1 NC_003143.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 4303382 pldA 1176669 pldA Yersinia pestis CO92 phospholipase A YP_002348712.1 4302504 R 214092 CDS YP_002348713.1 218930838 1176670 4303604..4304074 1 NC_003143.1 hypothetical protein 4304074 1176670 YPO3835 Yersinia pestis CO92 hypothetical protein YP_002348713.1 4303604 D 214092 CDS YP_002348714.1 218930839 1176671 4304161..4305051 1 NC_003143.1 hypothetical protein 4305051 rarD 1176671 rarD Yersinia pestis CO92 hypothetical protein YP_002348714.1 4304161 D 214092 CDS YP_002348715.1 218930840 1176672 complement(4305149..4306099) 1 NC_003143.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 4306099 corA 1176672 corA Yersinia pestis CO92 magnesium/nickel/cobalt transporter CorA YP_002348715.1 4305149 R 214092 CDS YP_002348716.1 218930841 1176673 complement(4306748..4307590) 1 NC_003143.1 hypothetical protein 4307590 1176673 YPO3838 Yersinia pestis CO92 hypothetical protein YP_002348716.1 4306748 R 214092 CDS YP_002348717.1 218930842 1176674 complement(4307604..4308821) 1 NC_003143.1 hypothetical protein 4308821 1176674 YPO3839 Yersinia pestis CO92 hypothetical protein YP_002348717.1 4307604 R 214092 CDS YP_002348718.1 218930843 1176675 4309249..4309935 1 NC_003143.1 TetR family regulatory protein 4309935 1176675 YPO3840 Yersinia pestis CO92 TetR family regulatory protein YP_002348718.1 4309249 D 214092 CDS YP_002348719.1 218930844 1176676 complement(4310049..4312211) 1 NC_003143.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 4312211 uvrD 1176676 uvrD Yersinia pestis CO92 DNA-dependent helicase II YP_002348719.1 4310049 R 214092 CDS YP_002348720.1 218930845 1176677 complement(4312313..4313029) 1 NC_003143.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 4313029 1176677 YPO3842 Yersinia pestis CO92 flavin mononucleotide phosphatase YP_002348720.1 4312313 R 214092 CDS YP_002348721.1 218930846 1176678 complement(4313029..4313940) 1 NC_003143.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 4313940 xerC 1176678 xerC Yersinia pestis CO92 site-specific tyrosine recombinase XerC YP_002348721.1 4313029 R 214092 CDS YP_002348722.1 218930847 1176679 complement(4313937..4314641) 1 NC_003143.1 hypothetical protein 4314641 1176679 YPO3844 Yersinia pestis CO92 hypothetical protein YP_002348722.1 4313937 R 214092 CDS YP_002348723.1 218930848 1176680 complement(4314706..4315530) 1 NC_003143.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 4315530 dapF 1176680 dapF Yersinia pestis CO92 diaminopimelate epimerase YP_002348723.1 4314706 R 214092 CDS YP_002348724.1 218930849 1176681 complement(4315714..4315902) 1 NC_003143.1 lipoprotein 4315902 1176681 YPO3846 Yersinia pestis CO92 lipoprotein YP_002348724.1 4315714 R 214092 CDS YP_002348725.1 218930850 1176682 4316054..4316374 1 NC_003143.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 4316374 cyaY 1176682 cyaY Yersinia pestis CO92 frataxin-like protein YP_002348725.1 4316054 D 214092 CDS YP_002348726.1 218930851 1176683 complement(4316618..4319170) 1 NC_003143.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 4319170 cyaA 1176683 cyaA Yersinia pestis CO92 adenylate cyclase YP_002348726.1 4316618 R 214092 CDS YP_008479733.1 537470197 16744782 4319234..4319443 1 NC_003143.1 hypothetical protein 4319443 16744782 YPO3848a Yersinia pestis CO92 hypothetical protein YP_008479733.1 4319234 D 214092 CDS YP_002348727.1 218930852 1176684 4319664..4320605 1 NC_003143.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 4320605 hemC 1176684 hemC Yersinia pestis CO92 porphobilinogen deaminase YP_002348727.1 4319664 D 214092 CDS YP_002348728.1 218930853 1176685 4320602..4321351 1 NC_003143.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 4321351 hemD 1176685 hemD Yersinia pestis CO92 uroporphyrinogen-III synthase YP_002348728.1 4320602 D 214092 CDS YP_002348729.1 218930854 1176686 4321382..4322506 1 NC_003143.1 uroporphyrinogen III C-methyltransferase 4322506 hemX 1176686 hemX Yersinia pestis CO92 uroporphyrinogen III C-methyltransferase YP_002348729.1 4321382 D 214092 CDS YP_002348730.1 218930855 1176687 4322509..4323729 1 NC_003143.1 protoheme IX biogenesis protein 4323729 hemY 1176687 hemY Yersinia pestis CO92 protoheme IX biogenesis protein YP_002348730.1 4322509 D 214092 CDS YP_002348731.1 218930856 1176688 complement(4323922..4324380) 1 NC_003143.1 transposase for the IS1541 insertion element 4324380 tnp 1176688 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348731.1 4323922 R 214092 CDS YP_002348732.1 218930857 1176693 complement(4325886..4327277) 1 NC_003143.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transport protein YifK 4327277 1176693 YPO3854 Yersinia pestis CO92 transport protein YifK YP_002348732.1 4325886 R 214092 CDS YP_002348733.1 218930858 1176694 complement(4327801..4328541) 1 NC_003143.1 UDP-N-acetyl-D-mannosaminuronic acid transferase 4328541 wecG 1176694 wecG Yersinia pestis CO92 UDP-N-acetyl-D-mannosaminuronic acid transferase YP_002348733.1 4327801 R 214092 CDS YP_002348734.1 218930859 1176695 complement(4328550..4329914) 1 NC_003143.1 enterobacterial common antigen polymerase; common antigen polymerase 4329914 wecF 1176695 wecF Yersinia pestis CO92 common antigen polymerase YP_002348734.1 4328550 R 214092 CDS YP_002348735.1 218930860 1176696 complement(4329911..4330996) 1 NC_003143.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 4330996 1176696 YPO3857 Yersinia pestis CO92 4-alpha-L-fucosyltransferase YP_002348735.1 4329911 R 214092 CDS YP_002348736.1 218930861 1176697 complement(4331019..4332275) 1 NC_003143.1 lipopolysaccharide biosynthesis protein 4332275 1176697 YPO3858 Yersinia pestis CO92 lipopolysaccharide biosynthesis protein YP_002348736.1 4331019 R 214092 CDS YP_002348737.1 218930862 1176698 complement(4332277..4333407) 1 NC_003143.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 4333407 rffA 1176698 rffA Yersinia pestis CO92 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_002348737.1 4332277 R 214092 CDS YP_002348738.1 218930863 1176699 complement(4333409..4334077) 1 NC_003143.1 TDP-fucosamine acetyltransferase 4334077 rffC 1176699 rffC Yersinia pestis CO92 TDP-fucosamine acetyltransferase YP_002348738.1 4333409 R 214092 CDS YP_002348739.1 218930864 1176700 complement(4334124..4335005) 1 NC_003143.1 glucose-1-phosphate thymidylyltransferase 4335005 rffH 1176700 rffH Yersinia pestis CO92 glucose-1-phosphate thymidylyltransferase YP_002348739.1 4334124 R 214092 CDS YP_002348740.1 218930865 1176701 complement(4335300..4336367) 1 NC_003143.1 dTDP-D-glucose-4,6-dehydratase 4336367 rffG 1176701 rffG Yersinia pestis CO92 dTDP-D-glucose-4,6-dehydratase YP_002348740.1 4335300 R 214092 CDS YP_002348741.1 218930866 1176702 complement(4336364..4337626) 1 NC_003143.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 4337626 wecC 1176702 wecC Yersinia pestis CO92 UDP-N-acetyl-D-mannosamine dehydrogenase YP_002348741.1 4336364 R 214092 CDS YP_002348742.1 218930867 1176703 complement(4337623..4338753) 1 NC_003143.1 UDP-N-acetylglucosamine 2-epimerase 4338753 nfrC 1176703 nfrC Yersinia pestis CO92 UDP-N-acetylglucosamine 2-epimerase YP_002348742.1 4337623 R 214092 CDS YP_002348743.1 218930868 1176704 complement(4339034..4340095) 1 NC_003143.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 4340095 wzzE 1176704 wzzE Yersinia pestis CO92 lipopolysaccharide biosynthesis protein WzzE YP_002348743.1 4339034 R 214092 CDS YP_002348744.1 218930869 1176705 complement(4340131..4341228) 1 NC_003143.1 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 4341228 1176705 YPO3866 Yersinia pestis CO92 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase YP_002348744.1 4340131 R 214092 CDS YP_002348745.1 218930870 1176706 complement(4341763..4343022) 1 NC_003143.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 4343022 rho 1176706 rho Yersinia pestis CO92 transcription termination factor Rho YP_002348745.1 4341763 R 214092 CDS YP_002348746.1 218930871 1176707 complement(4343502..4343828) 1 NC_003143.1 thioredoxin 4343828 fipA 1176707 fipA Yersinia pestis CO92 thioredoxin YP_002348746.1 4343502 R 214092 CDS YP_002348747.1 218930872 1176708 4343947..4345233 1 NC_003143.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 4345233 rhlB 1176708 rhlB Yersinia pestis CO92 ATP-dependent RNA helicase RhlB YP_002348747.1 4343947 D 214092 CDS YP_002348748.1 218930873 1176710 complement(4346899..4348920) 1 NC_003143.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 4348920 rep 1176710 rep Yersinia pestis CO92 ATP-dependent DNA helicase Rep YP_002348748.1 4346899 R 214092 CDS YP_002348749.1 218930874 1176711 4349124..4349405 1 NC_003143.1 peptidyl-prolyl cis-trans isomerase C 4349405 ppiC 1176711 ppiC Yersinia pestis CO92 peptidyl-prolyl cis-trans isomerase C YP_002348749.1 4349124 D 214092 CDS YP_002348750.1 218930875 1176712 4349644..4350435 1 NC_003143.1 hypothetical protein 4350435 1176712 YPO3874 Yersinia pestis CO92 hypothetical protein YP_002348750.1 4349644 D 214092 CDS YP_002348751.1 218930876 1176713 4350532..4351740 1 NC_003143.1 transposase for the IS285 insertion element 4351740 y1062 1176713 y1062 Yersinia pestis CO92 transposase for the IS285 insertion element YP_002348751.1 4350532 D 214092 CDS YP_002348752.1 218930877 1176714 complement(4352063..4352290) 1 NC_003143.1 no significant database hits. CDS DNA has a low G+C content, 24.12%; hypothetical protein 4352290 1176714 YPO3876 Yersinia pestis CO92 hypothetical protein YP_002348752.1 4352063 R 214092 CDS YP_002348753.1 218930878 1176715 4352550..4353080 1 NC_003143.1 fimbrial protein 4353080 1176715 YPO3877 Yersinia pestis CO92 fimbrial protein YP_002348753.1 4352550 D 214092 CDS YP_002348754.1 218930879 1176716 4353144..4353875 1 NC_003143.1 fimbrial chaperone 4353875 1176716 YPO3878 Yersinia pestis CO92 fimbrial chaperone YP_002348754.1 4353144 D 214092 CDS YP_002348755.1 218930880 1176717 4353903..4356530 1 NC_003143.1 outer membrane usher protein 4356530 1176717 YPO3879 Yersinia pestis CO92 outer membrane usher protein YP_002348755.1 4353903 D 214092 CDS YP_002348756.1 218930881 1176718 4356547..4357914 1 NC_003143.1 hypothetical protein 4357914 1176718 YPO3880 Yersinia pestis CO92 hypothetical protein YP_002348756.1 4356547 D 214092 CDS YP_002348757.1 218930882 1176719 4357952..4358698 1 NC_003143.1 chaperone protein 4358698 1176719 YPO3881 Yersinia pestis CO92 chaperone protein YP_002348757.1 4357952 D 214092 CDS YP_002348759.1 218930884 1176721 complement(4359333..4359590) 1 NC_003143.1 colicin immunity protein 4359590 imm 1176721 imm Yersinia pestis CO92 colicin immunity protein YP_002348759.1 4359333 R 214092 CDS YP_002348761.1 218930886 1176723 complement(4360096..4360359) 1 NC_003143.1 no significant database hits; hypothetical protein 4360359 1176723 YPO3885 Yersinia pestis CO92 hypothetical protein YP_002348761.1 4360096 R 214092 CDS YP_002348764.1 218930889 1176726 complement(4362378..4363856) 1 NC_003143.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 4363856 ilvC 1176726 ilvC Yersinia pestis CO92 ketol-acid reductoisomerase YP_002348764.1 4362378 R 214092 CDS YP_002348765.1 218930890 1176727 4364142..4365023 1 NC_003143.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 4365023 ilvY 1176727 ilvY Yersinia pestis CO92 DNA-binding transcriptional regulator IlvY YP_002348765.1 4364142 D 214092 CDS YP_002348766.1 218930891 1176728 complement(4365078..4365287) 1 NC_003143.1 no significant database hits; hypothetical protein 4365287 1176728 YPO3890 Yersinia pestis CO92 hypothetical protein YP_002348766.1 4365078 R 214092 CDS YP_002348769.1 218930894 1176731 4366838..4367299 1 NC_003143.1 hypothetical protein 4367299 1176731 YPO3893 Yersinia pestis CO92 hypothetical protein YP_002348769.1 4366838 D 214092 CDS YP_002348770.1 218930895 1176732 4367358..4367840 1 NC_003143.1 No significant database matches. Similar to YPO3893 (97.6% identity in 123 aa overlap), YPO3895 (67.1% identity in 161 aa overlap), YPO3935 (66.0% identity in 159 aa overlap) and YPO2860 (53.8% identity in 160 aa overlap); hypothetical protein 4367840 1176732 YPO3894 Yersinia pestis CO92 hypothetical protein YP_002348770.1 4367358 D 214092 CDS YP_002348771.1 218930896 1176733 4367899..4368384 1 NC_003143.1 No significant database matches. Similar to YPO3935 (72.5% identity in 160 aa overlap), YPO3894 (67.1% identity in 161 aa overlap), YPO2860 (56.6% identity in 159 aa overlap) and YPO3893 (58.9% identity in 124 aa overlap); hypothetical protein 4368384 1176733 YPO3895 Yersinia pestis CO92 hypothetical protein YP_002348771.1 4367899 D 214092 CDS YP_002348772.1 218930897 1176734 complement(4368515..4370059) 1 NC_003143.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 4370059 ilvA 1176734 ilvA Yersinia pestis CO92 threonine dehydratase YP_002348772.1 4368515 R 214092 CDS YP_002348773.1 218930898 1176735 complement(4370065..4371915) 1 NC_003143.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 4371915 ilvD 1176735 ilvD Yersinia pestis CO92 dihydroxy-acid dehydratase YP_002348773.1 4370065 R 214092 CDS YP_002348774.1 218930899 1176736 complement(4372226..4373152) 1 NC_003143.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 4373152 ilvE 1176736 ilvE Yersinia pestis CO92 branched-chain amino acid aminotransferase YP_002348774.1 4372226 R 214092 CDS YP_002348775.1 218930900 1176737 complement(4373175..4373432) 1 NC_003143.1 acetolactate synthase 2 regulatory subunit 4373432 ilvM 1176737 ilvM Yersinia pestis CO92 acetolactate synthase 2 regulatory subunit YP_002348775.1 4373175 R 214092 CDS YP_002348776.1 218930901 1176738 complement(4373429..4375075) 1 NC_003143.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 4375075 ilvG 1176738 ilvG Yersinia pestis CO92 acetolactate synthase 2 catalytic subunit YP_002348776.1 4373429 R 214092 CDS YP_002348777.1 218930902 1176739 4375698..4377221 1 NC_003143.1 magnesium chelatase family protein 4377221 1176739 YPO3902 Yersinia pestis CO92 magnesium chelatase family protein YP_002348777.1 4375698 D 214092 CDS YP_002348778.1 218930903 1176740 complement(4377478..4377816) 1 NC_003143.1 hypothetical protein 4377816 1176740 YPO3903 Yersinia pestis CO92 hypothetical protein YP_002348778.1 4377478 R 214092 CDS YP_002348779.1 218930904 1176741 4377935..4378816 1 NC_003143.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 4378816 1176741 YPO3904 Yersinia pestis CO92 transcriptional regulator HdfR YP_002348779.1 4377935 D 214092 CDS YP_002348780.1 218930905 1176742 complement(4378803..4379795) 1 NC_003143.1 membrane component of a sugar ABC transporter system; ABC transporter permease 4379795 1176742 YPO3905 Yersinia pestis CO92 ABC transporter permease YP_002348780.1 4378803 R 214092 CDS YP_002348781.1 218930906 1176743 complement(4379795..4380814) 1 NC_003143.1 sugar transport system permease 4380814 1176743 YPO3906 Yersinia pestis CO92 sugar transport system permease YP_002348781.1 4379795 R 214092 CDS YP_002348782.1 218930907 1176744 complement(4380826..4382316) 1 NC_003143.1 sugar transport system ATP-binding protein 4382316 1176744 YPO3907 Yersinia pestis CO92 sugar transport system ATP-binding protein YP_002348782.1 4380826 R 214092 CDS YP_002348783.1 218930908 1176745 complement(4382402..4383358) 1 NC_003143.1 periplasmic protein 4383358 1176745 YPO3908 Yersinia pestis CO92 periplasmic protein YP_002348783.1 4382402 R 214092 CDS YP_008479734.1 537470198 16744783 4389766..4389951 1 NC_003143.1 hypothetical protein 4389951 16744783 YPO3909a Yersinia pestis CO92 hypothetical protein YP_008479734.1 4389766 D 214092 CDS YP_002348784.1 218930909 1176752 complement(4390216..4391079) 1 NC_003143.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 4391079 murI 1176752 murI Yersinia pestis CO92 glutamate racemase YP_002348784.1 4390216 R 214092 CDS YP_002348785.2 229220642 1176753 complement(4391024..4392919) 1 NC_003143.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 4392919 btuB 1176753 btuB Yersinia pestis CO92 vitamin B12/cobalamin outer membrane transporter YP_002348785.2 4391024 R 214092 CDS YP_002348786.1 218930911 1176754 4393381..4394484 1 NC_003143.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 4394484 trmA 1176754 trmA Yersinia pestis CO92 tRNA (uracil-5-)-methyltransferase YP_002348786.1 4393381 D 214092 CDS YP_002348787.1 218930912 1176755 complement(4394618..4395025) 1 NC_003143.1 hypothetical protein 4395025 yijD 1176755 yijD Yersinia pestis CO92 hypothetical protein YP_002348787.1 4394618 R 214092 CDS YP_002348788.1 218930913 1176756 complement(4395038..4395685) 1 NC_003143.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 4395685 1176756 YPO3913 Yersinia pestis CO92 DNA-binding transcriptional repressor FabR YP_002348788.1 4395038 R 214092 CDS YP_002348789.1 218930914 1176757 4395891..4397291 1 NC_003143.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 4397291 sthA 1176757 sthA Yersinia pestis CO92 soluble pyridine nucleotide transhydrogenase YP_002348789.1 4395891 D 214092 CDS YP_002348790.1 218930915 1176758 complement(4397274..4398191) 1 NC_003143.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 4398191 oxyR 1176758 oxyR Yersinia pestis CO92 DNA-binding transcriptional regulator OxyR YP_002348790.1 4397274 R 214092 CDS YP_002348791.1 218930916 1176759 4398338..4399069 1 NC_003143.1 peroxiredoxin/glutaredoxin family protein 4399069 1176759 YPO3916 Yersinia pestis CO92 peroxiredoxin/glutaredoxin family protein YP_002348791.1 4398338 D 214092 CDS YP_002348792.1 218930917 1176760 4399164..4400627 1 NC_003143.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 4400627 1176760 YPO3917 Yersinia pestis CO92 dihydrolipoamide dehydrogenase YP_002348792.1 4399164 D 214092 CDS YP_002348793.1 218930918 1176761 complement(4400743..4401546) 1 NC_003143.1 hypothetical protein 4401546 1176761 YPO3918 Yersinia pestis CO92 hypothetical protein YP_002348793.1 4400743 R 214092 CDS YP_002348794.1 218930919 1176762 complement(4401611..4402939) 1 NC_003143.1 HlyD family secretion protein 4402939 1176762 YPO3919 Yersinia pestis CO92 HlyD family secretion protein YP_002348794.1 4401611 R 214092 CDS YP_002348795.1 218930920 1176763 complement(4403015..4404823) 1 NC_003143.1 ABC transporter protein 4404823 1176763 YPO3920 Yersinia pestis CO92 ABC transporter protein YP_002348795.1 4403015 R 214092 CDS YP_002348796.1 218930921 1176764 complement(4404989..4405606) 1 NC_003143.1 hemophore HasA 4405606 1176764 YPO3922 Yersinia pestis CO92 hemophore HasA YP_002348796.1 4404989 R 214092 CDS YP_002348797.1 218930922 1176765 complement(4405828..4408320) 1 NC_003143.1 TonB dependent receptor protein 4408320 1176765 YPO3923 Yersinia pestis CO92 TonB dependent receptor protein YP_002348797.1 4405828 R 214092 CDS YP_002348798.1 218930923 1176766 complement(4408919..4410292) 1 NC_003143.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 4410292 argH 1176766 argH Yersinia pestis CO92 argininosuccinate lyase YP_002348798.1 4408919 R 214092 CDS YP_002348799.1 218930924 1176767 complement(4410459..4411232) 1 NC_003143.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 4411232 argB 1176767 argB Yersinia pestis CO92 acetylglutamate kinase YP_002348799.1 4410459 R 214092 CDS YP_002348800.1 218930925 1176768 complement(4411401..4412405) 1 NC_003143.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 4412405 argC 1176768 argC Yersinia pestis CO92 N-acetyl-gamma-glutamyl-phosphate reductase YP_002348800.1 4411401 R 214092 CDS YP_002348801.1 218930926 1176769 4412650..4413819 1 NC_003143.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 4413819 argE 1176769 argE Yersinia pestis CO92 acetylornithine deacetylase YP_002348801.1 4412650 D 214092 CDS YP_002348802.1 218930927 1176770 4414193..4416829 1 NC_003143.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 4416829 ppc 1176770 ppc Yersinia pestis CO92 phosphoenolpyruvate carboxylase YP_002348802.1 4414193 D 214092 CDS YP_002348803.2 537470199 1176771 4417442..4418086 1 NC_003143.1 insertion element IS1661 DNA-binding protein 4418086 1176771 YPO3931 Yersinia pestis CO92 insertion element IS1661 DNA-binding protein YP_002348803.2 4417442 D 214092 CDS YP_002348804.1 218930929 1176772 4418140..4418925 1 NC_003143.1 transposase for insertion sequence IS1661 4418925 1176772 YPO3932 Yersinia pestis CO92 transposase for insertion sequence IS1661 YP_002348804.1 4418140 D 214092 CDS YP_002348806.1 218930931 1176774 complement(4419714..4420178) 1 NC_003143.1 hypothetical protein 4420178 1176774 YPO3935 Yersinia pestis CO92 hypothetical protein YP_002348806.1 4419714 R 214092 CDS YP_002348808.1 218930933 1176776 4421260..4422681 1 NC_003143.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 4422681 glpD 1176776 glpD Yersinia pestis CO92 glycerol-3-phosphate dehydrogenase YP_002348808.1 4421260 D 214092 CDS YP_002348809.1 218930934 1176777 complement(4422844..4425291) 1 NC_003143.1 glycogen phosphorylase 4425291 glgP 1176777 glgP Yersinia pestis CO92 glycogen phosphorylase YP_002348809.1 4422844 R 214092 CDS YP_002348810.1 218930935 1176778 complement(4425460..4426890) 1 NC_003143.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 4426890 glgA 1176778 glgA Yersinia pestis CO92 glycogen synthase YP_002348810.1 4425460 R 214092 CDS YP_002348811.1 218930936 1176779 complement(4426958..4428388) 1 NC_003143.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 4428388 glgC 1176779 glgC Yersinia pestis CO92 glucose-1-phosphate adenylyltransferase YP_002348811.1 4426958 R 214092 CDS YP_002348812.1 218930937 1176780 complement(4428398..4430386) 1 NC_003143.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein 4430386 glgX 1176780 glgX Yersinia pestis CO92 glycogen debranching protein YP_002348812.1 4428398 R 214092 CDS YP_002348813.1 218930938 1176781 complement(4430388..4432571) 1 NC_003143.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 4432571 glgB 1176781 glgB Yersinia pestis CO92 glycogen branching protein YP_002348813.1 4430388 R 214092 CDS YP_002348814.1 218930939 1176782 4433077..4434774 1 NC_003143.1 hypothetical protein 4434774 1176782 YPO3943 Yersinia pestis CO92 hypothetical protein YP_002348814.1 4433077 D 214092 CDS YP_002348815.1 218930940 1176783 complement(4434982..4444023) 1 NC_003143.1 invasin 4444023 1176783 YPO3944 Yersinia pestis CO92 invasin YP_002348815.1 4434982 R 214092 CDS YP_002348817.1 218930942 1176785 complement(4445759..4446046) 1 NC_003143.1 no significant database hits; hypothetical protein 4446046 1176785 YPO3946 Yersinia pestis CO92 hypothetical protein YP_002348817.1 4445759 R 214092 CDS YP_002348818.1 218930943 1176786 complement(4446053..4446427) 1 NC_003143.1 no significant database hits; hypothetical protein 4446427 1176786 YPO3947 Yersinia pestis CO92 hypothetical protein YP_002348818.1 4446053 R 214092 CDS YP_002348819.1 218930944 1176787 complement(4446668..4446949) 1 NC_003143.1 no significant database hits; hypothetical protein 4446949 1176787 YPO3948 Yersinia pestis CO92 hypothetical protein YP_002348819.1 4446668 R 214092 CDS YP_002348820.1 218930945 1176788 complement(4447118..4448221) 1 NC_003143.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 4448221 asd 1176788 asd Yersinia pestis CO92 aspartate-semialdehyde dehydrogenase YP_002348820.1 4447118 R 214092 CDS YP_002348821.1 218930946 1176789 4448588..4449172 1 NC_003143.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 4449172 yhgN 1176789 yhgN Yersinia pestis CO92 dITP- and XTP- hydrolase YP_002348821.1 4448588 D 214092 CDS YP_002348822.1 218930947 1176790 complement(4449412..4449816) 1 NC_003143.1 hypothetical protein 4449816 1176790 YPO3951 Yersinia pestis CO92 hypothetical protein YP_002348822.1 4449412 R 214092 CDS YP_002348823.1 218930948 1176791 complement(4450187..4450420) 1 NC_003143.1 no significant database hits to the full length CDS. Similar to the N-terminal regions of YPO0639 (59.5% identity in 79 aa overlap) and YPO1258 (59.5% identity in 79 aa overlap); hypothetical protein 4450420 1176791 YPO3952 Yersinia pestis CO92 hypothetical protein YP_002348823.1 4450187 R 214092 CDS YP_002348824.1 218930949 1176792 complement(4450602..4451105) 1 NC_003143.1 gluconokinase 4451105 1176792 YPO3953 Yersinia pestis CO92 gluconokinase YP_002348824.1 4450602 R 214092 CDS YP_002348825.1 218930950 1176793 4451322..4452638 1 NC_003143.1 gluconate permease 4452638 gntM 1176793 gntM Yersinia pestis CO92 gluconate permease YP_002348825.1 4451322 D 214092 CDS YP_002348826.1 218930951 1176794 complement(4452730..4453725) 1 NC_003143.1 gluconate utilization system Gnt-I transcriptional repressor 4453725 gntR 1176794 gntR Yersinia pestis CO92 gluconate utilization system Gnt-I transcriptional repressor YP_002348826.1 4452730 R 214092 CDS YP_002348827.1 218930952 1176795 complement(4453854..4454549) 1 NC_003143.1 hypothetical protein 4454549 1176795 YPO3956 Yersinia pestis CO92 hypothetical protein YP_002348827.1 4453854 R 214092 CDS YP_002348828.1 218930953 1176796 4455044..4455313 1 NC_003143.1 no significant database hits; hypothetical protein 4455313 1176796 YPO3957 Yersinia pestis CO92 hypothetical protein YP_002348828.1 4455044 D 214092 CDS YP_002348829.1 218930954 1176797 4455313..4456050 1 NC_003143.1 response regulator protein 4456050 1176797 YPO3958 Yersinia pestis CO92 response regulator protein YP_002348829.1 4455313 D 214092 CDS YP_002348830.1 218930955 1176798 complement(4456235..4457242) 1 NC_003143.1 PfkB family carbohydrate kinase 4457242 1176798 YPO3959 Yersinia pestis CO92 PfkB family carbohydrate kinase YP_002348830.1 4456235 R 214092 CDS YP_002348831.1 218930956 1176799 complement(4457252..4458112) 1 NC_003143.1 hypothetical protein 4458112 1176799 YPO3960 Yersinia pestis CO92 hypothetical protein YP_002348831.1 4457252 R 214092 CDS YP_002348832.1 218930957 1176800 complement(4458138..4458821) 1 NC_003143.1 hypothetical protein 4458821 1176800 YPO3961 Yersinia pestis CO92 hypothetical protein YP_002348832.1 4458138 R 214092 CDS YP_002348833.1 218930958 1176801 complement(4458896..4459840) 1 NC_003143.1 sugar-binding transport protein 4459840 1176801 YPO3962 Yersinia pestis CO92 sugar-binding transport protein YP_002348833.1 4458896 R 214092 CDS YP_002348834.1 218930959 1176802 complement(4459871..4460863) 1 NC_003143.1 sugar transport system permease 4460863 1176802 YPO3963 Yersinia pestis CO92 sugar transport system permease YP_002348834.1 4459871 R 214092 CDS YP_002348835.1 218930960 1176803 complement(4460856..4462379) 1 NC_003143.1 sugar transport ATP-binding protein 4462379 1176803 YPO3964 Yersinia pestis CO92 sugar transport ATP-binding protein YP_002348835.1 4460856 R 214092 CDS YP_002348836.1 218930961 1176804 4462568..4465123 1 NC_003143.1 hybrid two-component system regulatory protein 4465123 1176804 YPO3965 Yersinia pestis CO92 hybrid two-component system regulatory protein YP_002348836.1 4462568 D 214092 CDS YP_002348837.1 218930962 1176805 complement(4465259..4466455) 1 NC_003143.1 hypothetical protein 4466455 1176805 YPO3966 Yersinia pestis CO92 hypothetical protein YP_002348837.1 4465259 R 214092 CDS YP_002348838.1 218930963 1176806 4466766..4468262 1 NC_003143.1 phosphate transport protein 4468262 1176806 YPO3967 Yersinia pestis CO92 phosphate transport protein YP_002348838.1 4466766 D 214092 CDS YP_002348839.1 218930964 1176807 4468528..4468986 1 NC_003143.1 transposase for the IS1541 insertion element 4468986 tnp 1176807 tnp Yersinia pestis CO92 transposase for the IS1541 insertion element YP_002348839.1 4468528 D 214092 CDS YP_002348840.1 218930965 1176808 complement(4469119..4469454) 1 NC_003143.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 4469454 uspB 1176808 uspB Yersinia pestis CO92 universal stress protein UspB YP_002348840.1 4469119 R 214092 CDS YP_002348841.1 218930966 1176809 4470162..4470608 1 NC_003143.1 universal stress protein A 4470608 uspA 1176809 uspA Yersinia pestis CO92 universal stress protein A YP_002348841.1 4470162 D 214092 CDS YP_002348842.1 218930967 1176810 4470855..4472198 1 NC_003143.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 4472198 gdhA 1176810 gdhA Yersinia pestis CO92 glutamate dehydrogenase YP_002348842.1 4470855 D 214092 CDS YP_002348843.1 218930968 1176811 4472443..4473780 1 NC_003143.1 metalloprotease 4473780 1176811 YPO3973 Yersinia pestis CO92 metalloprotease YP_002348843.1 4472443 D 214092 CDS YP_002348844.1 218930969 1176812 complement(4473845..4474615) 1 NC_003143.1 predicted SAM-dependent methyltransferase; methyltransferase 4474615 1176812 YPO3974 Yersinia pestis CO92 methyltransferase YP_002348844.1 4473845 R 214092 CDS YP_002348845.1 218930970 1176813 complement(4474619..4476661) 1 NC_003143.1 oligopeptidase A 4476661 opdA 1176813 opdA Yersinia pestis CO92 oligopeptidase A YP_002348845.1 4474619 R 214092 CDS YP_002348846.1 218930971 1176814 4476990..4477832 1 NC_003143.1 hypothetical protein 4477832 1176814 YPO3976 Yersinia pestis CO92 hypothetical protein YP_002348846.1 4476990 D 214092 CDS YP_002348847.1 218930972 1176815 4478018..4479370 1 NC_003143.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 4479370 gor 1176815 gor Yersinia pestis CO92 glutathione reductase YP_002348847.1 4478018 D 214092 CDS YP_002348848.1 218930973 1176816 4479562..4480689 1 NC_003143.1 regulatory protein 4480689 1176816 YPO3978 Yersinia pestis CO92 regulatory protein YP_002348848.1 4479562 D 214092 CDS YP_002348849.1 218930974 1176817 4480867..4482135 1 NC_003143.1 GntP family permease 4482135 1176817 YPO3979 Yersinia pestis CO92 GntP family permease YP_002348849.1 4480867 D 214092 CDS YP_002348850.1 218930975 1176818 4482146..4483282 1 NC_003143.1 glycerate kinase 4483282 glxK 1176818 glxK Yersinia pestis CO92 glycerate kinase YP_002348850.1 4482146 D 214092 CDS YP_002348851.1 218930976 1176819 complement(4483528..4484034) 1 NC_003143.1 No significant database matches. Similar to YPO3982 (60.7% identity in 168 aa overlap); hypothetical protein 4484034 1176819 YPO3981 Yersinia pestis CO92 hypothetical protein YP_002348851.1 4483528 R 214092 CDS YP_002348852.1 218930977 1176820 complement(4484102..4484599) 1 NC_003143.1 hypothetical protein 4484599 1176820 YPO3982 Yersinia pestis CO92 hypothetical protein YP_002348852.1 4484102 R 214092 CDS YP_002348853.1 218930978 1176821 complement(4484601..4485470) 1 NC_003143.1 hypothetical protein 4485470 1176821 YPO3983 Yersinia pestis CO92 hypothetical protein YP_002348853.1 4484601 R 214092 CDS YP_002348854.1 218930979 1176822 complement(4485558..4488770) 1 NC_003143.1 autotransporter protein 4488770 yapE 1176822 yapE Yersinia pestis CO92 autotransporter protein YP_002348854.1 4485558 R 214092 CDS YP_002348855.1 218930980 1176823 4489448..4490530 1 NC_003143.1 hypothetical protein 4490530 1176823 YPO3985 Yersinia pestis CO92 hypothetical protein YP_002348855.1 4489448 D 214092 CDS YP_002348856.1 218930981 1176824 4490555..4491331 1 NC_003143.1 CDP-diacylglycerol pyrophosphatase 4491331 cdh 1176824 cdh Yersinia pestis CO92 CDP-diacylglycerol pyrophosphatase YP_002348856.1 4490555 D 214092 CDS YP_002348857.1 218930982 1176825 complement(4491308..4493530) 1 NC_003143.1 hypothetical protein 4493530 1176825 YPO3987 Yersinia pestis CO92 hypothetical protein YP_002348857.1 4491308 R 214092 CDS YP_002348858.1 218930983 1176826 complement(4493835..4494665) 1 NC_003143.1 in Escherichia coli this protein is involved in flagellar function; diguanylate phosphodiesterase 4494665 1176826 YPO3988 Yersinia pestis CO92 diguanylate phosphodiesterase YP_002348858.1 4493835 R 214092 CDS YP_002348859.1 218930984 1176827 4494899..4495099 1 NC_003143.1 tautomerase 4495099 1176827 YPO3989 Yersinia pestis CO92 tautomerase YP_002348859.1 4494899 D 214092 CDS YP_002348860.1 218930985 1176828 4495378..4496322 1 NC_003143.1 2-dehydro-3-deoxygluconokinase 4496322 kdgK 1176828 kdgK Yersinia pestis CO92 2-dehydro-3-deoxygluconokinase YP_002348860.1 4495378 D 214092 CDS YP_002348861.1 218930986 1176829 complement(4496486..4497985) 1 NC_003143.1 insulinase family protease 4497985 1176829 YPO3991 Yersinia pestis CO92 insulinase family protease YP_002348861.1 4496486 R 214092 CDS YP_002348862.1 218930987 1176830 complement(4498350..4499639) 1 NC_003143.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 4499639 dctA 1176830 dctA Yersinia pestis CO92 C4-dicarboxylate transporter DctA YP_002348862.1 4498350 R 214092 CDS YP_002348863.1 218930988 1176831 complement(4500094..4500573) 1 NC_003143.1 hypothetical protein 4500573 1176831 YPO3993 Yersinia pestis CO92 hypothetical protein YP_002348863.1 4500094 R 214092 CDS YP_002348864.1 218930989 1176832 complement(4500698..4502416) 1 NC_003143.1 periplasmic pectate lyase 4502416 pelY 1176832 pelY Yersinia pestis CO92 periplasmic pectate lyase YP_002348864.1 4500698 R 214092 CDS YP_002348865.1 218930990 1176833 complement(4502662..4503366) 1 NC_003143.1 hypothetical protein 4503366 1176833 YPO3995 Yersinia pestis CO92 hypothetical protein YP_002348865.1 4502662 R 214092 CDS YP_002348866.1 218930991 1176834 complement(4504006..4506192) 1 NC_003143.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; biofilm formation regulator HmsP 4506192 yhjK 1176834 yhjK Yersinia pestis CO92 biofilm formation regulator HmsP YP_002348866.1 4504006 R 214092 CDS YP_002348867.1 218930992 1176836 complement(4507553..4508629) 1 NC_003143.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding protein 4508629 dppF 1176836 dppF Yersinia pestis CO92 dipeptide transporter ATP-binding protein YP_002348867.1 4507553 R 214092 CDS YP_002348868.1 218930993 1176837 complement(4508626..4509606) 1 NC_003143.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding protein 4509606 dppD 1176837 dppD Yersinia pestis CO92 dipeptide transporter ATP-binding protein YP_002348868.1 4508626 R 214092 CDS YP_002348869.1 218930994 1176838 complement(4509620..4510522) 1 NC_003143.1 dipeptide transporter 4510522 dppC 1176838 dppC Yersinia pestis CO92 dipeptide transporter YP_002348869.1 4509620 R 214092 CDS YP_002348870.1 218930995 1176839 complement(4510604..4511551) 1 NC_003143.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 4511551 dppB 1176839 dppB Yersinia pestis CO92 dipeptide transporter permease DppB YP_002348870.1 4510604 R 214092 CDS YP_002348871.1 218930996 1176840 complement(4511834..4513441) 1 NC_003143.1 periplasmic dipeptide transport protein 4513441 dppA 1176840 dppA Yersinia pestis CO92 periplasmic dipeptide transport protein YP_002348871.1 4511834 R 214092 CDS YP_002348872.1 218930997 1176841 complement(4513844..4514092) 1 NC_003143.1 doubtful CDS with no significant database hits; hypothetical protein 4514092 1176841 YPO4004 Yersinia pestis CO92 hypothetical protein YP_002348872.1 4513844 R 214092 CDS YP_002348873.1 218930998 1176842 complement(4514110..4515873) 1 NC_003143.1 hemolysin activator protein 4515873 1176842 YPO4005 Yersinia pestis CO92 hemolysin activator protein YP_002348873.1 4514110 R 214092 CDS YP_002348874.1 218930999 1176843 complement(4515982..4517373) 1 NC_003143.1 hypothetical protein 4517373 1176843 YPO4006 Yersinia pestis CO92 hypothetical protein YP_002348874.1 4515982 R 214092 CDS YP_002348875.1 218931000 1176845 complement(4517879..4519210) 1 NC_003143.1 membrane protein regulates uhpT expression; regulatory protein UhpC 4519210 uhpC 1176845 uhpC Yersinia pestis CO92 regulatory protein UhpC YP_002348875.1 4517879 R 214092 CDS YP_002348876.1 218931001 1176847 complement(4520110..4520892) 1 NC_003143.1 transposase/IS protein 4520892 1176847 YPO4009 Yersinia pestis CO92 transposase/IS protein YP_002348876.1 4520110 R 214092 CDS YP_002348877.1 218931002 1176848 complement(4520889..4521911) 1 NC_003143.1 transposase for insertion sequence IS100 4521911 y1093 1176848 y1093 Yersinia pestis CO92 transposase for insertion sequence IS100 YP_002348877.1 4520889 R 214092 CDS YP_002348878.1 218931003 1176849 complement(4522790..4523380) 1 NC_003143.1 two-component system response regulator 4523380 uhpA 1176849 uhpA Yersinia pestis CO92 two-component system response regulator YP_002348878.1 4522790 R 214092 CDS YP_002348879.1 218931004 1176850 complement(4523496..4525187) 1 NC_003143.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 4525187 yhjW 1176850 yhjW Yersinia pestis CO92 phosphoethanolamine transferase YP_002348879.1 4523496 R 214092 CDS YP_002348880.1 218931005 1176851 complement(4525716..4527179) 1 NC_003143.1 hypothetical protein 4527179 1176851 YPO4014 Yersinia pestis CO92 hypothetical protein YP_002348880.1 4525716 R 214092 CDS YP_002348881.1 218931006 1176852 complement(4527647..4529050) 1 NC_003143.1 amino acid permease 4529050 1176852 YPO4015 Yersinia pestis CO92 amino acid permease YP_002348881.1 4527647 R 214092 CDS YP_002348882.1 218931007 1176853 complement(4529468..4531000) 1 NC_003143.1 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 4531000 hutH 1176853 hutH Yersinia pestis CO92 histidine ammonia-lyase YP_002348882.1 4529468 R 214092 CDS YP_002348883.1 218931008 1176854 complement(4530997..4532688) 1 NC_003143.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 4532688 hutU 1176854 hutU Yersinia pestis CO92 urocanate hydratase YP_002348883.1 4530997 R 214092 CDS YP_002348884.1 218931009 1176855 4533415..4534359 1 NC_003143.1 pyridoxal-phosphate dependent protein 4534359 cysM 1176855 cysM Yersinia pestis CO92 pyridoxal-phosphate dependent protein YP_002348884.1 4533415 D 214092 CDS YP_002348885.1 218931010 1176856 4534356..4534922 1 NC_003143.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 4534922 1176856 YPO4019 Yersinia pestis CO92 adenine phosphoribosyltransferase YP_002348885.1 4534356 D 214092 CDS YP_002348886.1 218931011 1176857 4535005..4535934 1 NC_003143.1 hypothetical protein 4535934 1176857 YPO4020 Yersinia pestis CO92 hypothetical protein YP_002348886.1 4535005 D 214092 CDS YP_002348887.1 218931012 1176858 4535936..4537180 1 NC_003143.1 hypothetical protein 4537180 1176858 YPO4021 Yersinia pestis CO92 hypothetical protein YP_002348887.1 4535936 D 214092 CDS YP_002348888.1 218931013 1176859 4537703..4538656 1 NC_003143.1 iron transport protein 4538656 1176859 YPO4022 Yersinia pestis CO92 iron transport protein YP_002348888.1 4537703 D 214092 CDS YP_002348889.1 218931014 1176860 4538666..4539625 1 NC_003143.1 iron transport permease 4539625 1176860 YPO4023 Yersinia pestis CO92 iron transport permease YP_002348889.1 4538666 D 214092 CDS YP_002348890.1 218931015 1176861 4539615..4540622 1 NC_003143.1 iron transport permease 4540622 1176861 YPO4024 Yersinia pestis CO92 iron transport permease YP_002348890.1 4539615 D 214092 CDS YP_002348891.1 218931016 1176862 4540619..4541377 1 NC_003143.1 iron ABC transporter ATP-binding protein 4541377 1176862 YPO4025 Yersinia pestis CO92 iron ABC transporter ATP-binding protein YP_002348891.1 4540619 D 214092 CDS YP_002348893.1 218931018 1176864 4543227..4543589 1 NC_003143.1 regulator 4543589 1176864 YPO4028 Yersinia pestis CO92 regulator YP_002348893.1 4543227 D 214092 CDS YP_002348894.1 218931019 1176866 4544734..4544979 1 NC_003143.1 regulatory protein 4544979 1176866 YPO4031 Yersinia pestis CO92 regulatory protein YP_002348894.1 4544734 D 214092 CDS YP_002348895.1 218931020 1176867 complement(4545247..4546554) 1 NC_003143.1 no significant database hits. CDS DNA has a low G+C content, 31.03%; hypothetical protein 4546554 1176867 YPO4032 Yersinia pestis CO92 hypothetical protein YP_002348895.1 4545247 R 214092 CDS YP_002348896.1 218931021 1176868 complement(4546613..4547806) 1 NC_003143.1 phage integrase 4547806 1176868 YPO4033 Yersinia pestis CO92 phage integrase YP_002348896.1 4546613 R 214092 CDS YP_002348897.1 218931022 1176870 complement(4548192..4549385) 1 NC_003143.1 AraC family transcriptional regulator 4549385 1176870 YPO4034 Yersinia pestis CO92 AraC family transcriptional regulator YP_002348897.1 4548192 R 214092 CDS YP_002348898.1 218931023 1176871 complement(4549475..4550659) 1 NC_003143.1 sugar transport system permease 4550659 1176871 YPO4035 Yersinia pestis CO92 sugar transport system permease YP_002348898.1 4549475 R 214092 CDS YP_002348899.1 218931024 1176872 complement(4550646..4552178) 1 NC_003143.1 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding protein 4552178 1176872 YPO4036 Yersinia pestis CO92 xylose transporter ATP-binding protein YP_002348899.1 4550646 R 214092 CDS YP_002348900.1 218931025 1176873 complement(4552386..4553381) 1 NC_003143.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity; D-xylose transporter subunit XylF 4553381 xylF 1176873 xylF Yersinia pestis CO92 D-xylose transporter subunit XylF YP_002348900.1 4552386 R 214092 CDS YP_002348901.1 218931026 1176874 4553844..4555163 1 NC_003143.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 4555163 xylA 1176874 xylA Yersinia pestis CO92 xylose isomerase YP_002348901.1 4553844 D 214092 CDS YP_002348902.1 218931027 1176875 4555287..4556741 1 NC_003143.1 xylulose kinase 4556741 xylB 1176875 xylB Yersinia pestis CO92 xylulose kinase YP_002348902.1 4555287 D 214092 CDS YP_002348903.1 218931028 1176876 complement(4556859..4557845) 1 NC_003143.1 hypothetical protein 4557845 1176876 YPO4040 Yersinia pestis CO92 hypothetical protein YP_002348903.1 4556859 R 214092 CDS YP_002348904.1 218931029 1176877 complement(4557884..4558651) 1 NC_003143.1 fimbrial chaperone 4558651 1176877 YPO4041 Yersinia pestis CO92 fimbrial chaperone YP_002348904.1 4557884 R 214092 CDS YP_002348905.1 218931030 1176879 complement(4561310..4561867) 1 NC_003143.1 fimbrial protein 4561867 1176879 YPO4044 Yersinia pestis CO92 fimbrial protein YP_002348905.1 4561310 R 214092 CDS YP_002348906.1 218931031 1176880 complement(4562749..4563741) 1 NC_003143.1 hypothetical protein 4563741 1176880 YPO4045 Yersinia pestis CO92 hypothetical protein YP_002348906.1 4562749 R 214092 CDS YP_002348907.2 537470200 1176881 4563975..4564619 1 NC_003143.1 insertion element IS1661 DNA-binding protein 4564619 1176881 YPO4046 Yersinia pestis CO92 insertion element IS1661 DNA-binding protein YP_002348907.2 4563975 D 214092 CDS YP_002348908.1 218931033 1176882 4564673..4565458 1 NC_003143.1 transposase for insertion sequence IS1661 4565458 1176882 YPO4047 Yersinia pestis CO92 transposase for insertion sequence IS1661 YP_002348908.1 4564673 D 214092 CDS YP_002348909.1 218931034 1176883 4565931..4567160 1 NC_003143.1 multidrug translocase 4567160 cmr 1176883 cmr Yersinia pestis CO92 multidrug translocase YP_002348909.1 4565931 D 214092 CDS YP_002348910.1 218931035 1176884 4567870..4568451 1 NC_003143.1 hypothetical protein 4568451 1176884 YPO4049 Yersinia pestis CO92 hypothetical protein YP_002348910.1 4567870 D 214092 CDS YP_002348911.1 218931036 1176885 complement(4568465..4568797) 1 NC_003143.1 hypothetical protein 4568797 1176885 YPO4050 Yersinia pestis CO92 hypothetical protein YP_002348911.1 4568465 R 214092 CDS YP_002348913.1 218931038 1176888 complement(4571507..4572895) 1 NC_003143.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 4572895 selA 1176888 selA Yersinia pestis CO92 selenocysteine synthase YP_002348913.1 4571507 R 214092 CDS YP_002348914.1 218931039 1176889 complement(4573079..4574008) 1 NC_003143.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 4574008 fdhE 1176889 fdhE Yersinia pestis CO92 formate dehydrogenase accessory protein FdhE YP_002348914.1 4573079 R 214092 CDS YP_002348915.1 218931040 1176890 complement(4574008..4574682) 1 NC_003143.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 4574682 fdoI 1176890 fdoI Yersinia pestis CO92 formate dehydrogenase-O subunit gamma YP_002348915.1 4574008 R 214092 CDS YP_002348916.1 218931041 1176891 complement(4574679..4575650) 1 NC_003143.1 formate dehydrogenase-O iron-sulfur subunit 4575650 fdoH 1176891 fdoH Yersinia pestis CO92 formate dehydrogenase-O iron-sulfur subunit YP_002348916.1 4574679 R 214092 CDS YP_002348917.1 218931042 1176893 4578907..4579731 1 NC_003143.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 4579731 fdhD 1176893 fdhD Yersinia pestis CO92 formate dehydrogenase accessory protein YP_002348917.1 4578907 D 214092 CDS YP_002348918.1 218931043 1176894 4580167..4580790 1 NC_003143.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 4580790 sodA 1176894 sodA Yersinia pestis CO92 superoxide dismutase YP_002348918.1 4580167 D 214092 CDS YP_002348919.1 218931044 1176895 4581134..4583083 1 NC_003143.1 methyl-accepting chemotaxis protein II 4583083 cheM 1176895 cheM Yersinia pestis CO92 methyl-accepting chemotaxis protein II YP_002348919.1 4581134 D 214092 CDS YP_002348920.1 218931045 1176896 4583273..4583605 1 NC_003143.1 hypothetical protein 4583605 1176896 YPO4063 Yersinia pestis CO92 hypothetical protein YP_002348920.1 4583273 D 214092 CDS YP_002348921.1 218931046 1176897 4584161..4584613 1 NC_003143.1 hypothetical protein 4584613 1176897 YPO4064 Yersinia pestis CO92 hypothetical protein YP_002348921.1 4584161 D 214092 CDS YP_002348922.1 218931047 1176898 complement(4584782..4585138) 1 NC_003143.1 hypothetical protein 4585138 1176898 YPO4065 Yersinia pestis CO92 hypothetical protein YP_002348922.1 4584782 R 214092 CDS YP_002348923.1 218931048 1176899 complement(4585387..4585941) 1 NC_003143.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 4585941 mtlR 1176899 mtlR Yersinia pestis CO92 mannitol repressor protein YP_002348923.1 4585387 R 214092 CDS YP_002348924.1 218931049 1176900 complement(4586148..4587311) 1 NC_003143.1 mannitol-1-phosphate 5-dehydrogenase 4587311 mtlD 1176900 mtlD Yersinia pestis CO92 mannitol-1-phosphate 5-dehydrogenase YP_002348924.1 4586148 R 214092 CDS YP_002348925.1 218931050 1176901 complement(4587448..4589379) 1 NC_003143.1 PTS system mannitol-specific transporter subunit IIABC 4589379 mtlA 1176901 mtlA Yersinia pestis CO92 PTS system mannitol-specific transporter subunit IIABC YP_002348925.1 4587448 R 214092 CDS YP_002348926.1 218931051 1176902 complement(4590029..4590754) 1 NC_003143.1 hypothetical protein 4590754 yiaF 1176902 yiaF Yersinia pestis CO92 hypothetical protein YP_002348926.1 4590029 R 214092 CDS YP_002348927.1 218931052 1176903 complement(4591221..4593290) 1 NC_003143.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 4593290 glyS 1176903 glyS Yersinia pestis CO92 glycyl-tRNA synthetase subunit beta YP_002348927.1 4591221 R 214092 CDS YP_002348928.1 218931053 1176904 complement(4593300..4594214) 1 NC_003143.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 4594214 glyQ 1176904 glyQ Yersinia pestis CO92 glycyl-tRNA synthetase subunit alpha YP_002348928.1 4593300 R 214092 CDS YP_002348929.1 218931054 1176905 4594542..4595114 1 NC_003143.1 DNA-3-methyladenine glycosylase 4595114 tag 1176905 tag Yersinia pestis CO92 DNA-3-methyladenine glycosylase YP_002348929.1 4594542 D 214092 CDS YP_002348930.1 218931055 1176906 4595111..4595566 1 NC_003143.1 hypothetical protein 4595566 1176906 YPO4075 Yersinia pestis CO92 hypothetical protein YP_002348930.1 4595111 D 214092 CDS YP_002348931.1 218931056 1176907 4595924..4596583 1 NC_003143.1 outer membrane lipoprotein 4596583 yiaD 1176907 yiaD Yersinia pestis CO92 outer membrane lipoprotein YP_002348931.1 4595924 D 214092 CDS YP_002348932.1 218931057 1176908 complement(4596714..4597358) 1 NC_003143.1 hypothetical protein 4597358 1176908 YPO4077 Yersinia pestis CO92 hypothetical protein YP_002348932.1 4596714 R 214092 CDS YP_002348933.1 218931058 1176909 4597877..4598857 1 NC_003143.1 D-isomer specific 2-hydroxyacid dehydrogenase 4598857 1176909 YPO4078 Yersinia pestis CO92 D-isomer specific 2-hydroxyacid dehydrogenase YP_002348933.1 4597877 D 214092 CDS YP_002348934.1 218931059 1176910 4599146..4601209 1 NC_003143.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 4601209 malS 1176910 malS Yersinia pestis CO92 periplasmic alpha-amylase YP_002348934.1 4599146 D 214092 CDS YP_002348935.1 218931060 1176911 4601624..4602067 1 NC_003143.1 Poor database matches; hypothetical protein 4602067 1176911 YPO4081 Yersinia pestis CO92 hypothetical protein YP_002348935.1 4601624 D 214092 CDS YP_002348936.1 218931061 1176912 4602522..4603787 1 NC_003143.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 4603787 avtA 1176912 avtA Yersinia pestis CO92 valine--pyruvate transaminase YP_002348936.1 4602522 D 214092 CDS YP_002348937.1 218931062 1176913 complement(4603900..4605558) 1 NC_003143.1 hypothetical protein 4605558 yidE 1176913 yidE Yersinia pestis CO92 hypothetical protein YP_002348937.1 4603900 R 214092 CDS YP_002348938.1 218931063 1176914 complement(4605931..4606395) 1 NC_003143.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 4606395 ibpB 1176914 ibpB Yersinia pestis CO92 heat shock chaperone IbpB YP_002348938.1 4605931 R 214092 CDS YP_002348939.1 218931064 1176915 complement(4606676..4607089) 1 NC_003143.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 4607089 ibpA 1176915 ibpA Yersinia pestis CO92 heat shock protein IbpA YP_002348939.1 4606676 R 214092 CDS YP_002348940.1 218931065 1176916 4607457..4607795 1 NC_003143.1 hypothetical protein 4607795 1176916 YPO4086 Yersinia pestis CO92 hypothetical protein YP_002348940.1 4607457 D 214092 CDS YP_002348941.1 218931066 1176918 4608658..4609620 1 NC_003143.1 hypothetical protein 4609620 1176918 YPO4089 Yersinia pestis CO92 hypothetical protein YP_002348941.1 4608658 D 214092 CDS YP_002348942.1 218931067 1176919 4609614..4610567 1 NC_003143.1 catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase 4610567 1176919 YPO4090 Yersinia pestis CO92 ornithine cyclodeaminase YP_002348942.1 4609614 D 214092 CDS YP_002348943.2 537470201 1176920 4610624..4611289 1 NC_003143.1 insertion element IS1661 DNA-binding protein 4611289 1176920 YPO4091 Yersinia pestis CO92 insertion element IS1661 DNA-binding protein YP_002348943.2 4610624 D 214092 CDS YP_002348944.1 218931069 1176921 4611343..4612128 1 NC_003143.1 transposase for insertion sequence IS1661 4612128 1176921 YPO4092 Yersinia pestis CO92 transposase for insertion sequence IS1661 YP_002348944.1 4611343 D 214092 CDS YP_002348945.1 218931070 1176922 complement(4612519..4613328) 1 NC_003143.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 4613328 1176922 YPO4093 Yersinia pestis CO92 sugar phosphatase YP_002348945.1 4612519 R 214092 CDS YP_002348946.1 218931071 1176923 complement(4613544..4615958) 1 NC_003143.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4615958 gyrB 1176923 gyrB Yersinia pestis CO92 DNA gyrase subunit B YP_002348946.1 4613544 R 214092 CDS YP_002348947.1 218931072 1176924 complement(4615978..4617063) 1 NC_003143.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4617063 recF 1176924 recF Yersinia pestis CO92 recombination protein F YP_002348947.1 4615978 R 214092 CDS YP_002348948.1 218931073 1176925 complement(4617236..4618336) 1 NC_003143.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4618336 dnaN 1176925 dnaN Yersinia pestis CO92 DNA polymerase III subunit beta YP_002348948.1 4617236 R 214092 CDS YP_002348949.1 218931074 1176926 complement(4618341..4619729) 1 NC_003143.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 4619729 dnaA 1176926 dnaA Yersinia pestis CO92 chromosome replication initiator DnaA YP_002348949.1 4618341 R 214092 CDS YP_002348950.1 218931075 1176927 4619853..4620062 1 NC_003143.1 no significant database hits; hypothetical protein 4620062 1176927 YPO4098 Yersinia pestis CO92 hypothetical protein YP_002348950.1 4619853 D 214092 CDS YP_002348951.1 218931076 1176928 4620439..4620579 1 NC_003143.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4620579 rpmH 1176928 rpmH Yersinia pestis CO92 50S ribosomal protein L34 YP_002348951.1 4620439 D 214092 CDS YP_002348952.1 218931077 1176929 4620598..4620957 1 NC_003143.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4620957 rnpA 1176929 rnpA Yersinia pestis CO92 ribonuclease P YP_002348952.1 4620598 D 214092 CDS YP_002348953.1 218931078 1176930 4621181..4622821 1 NC_003143.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4622821 yidC 1176930 yidC Yersinia pestis CO92 inner membrane protein translocase component YidC YP_002348953.1 4621181 D 214092 CDS YP_002348954.1 218931079 1176931 4622964..4624328 1 NC_003143.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4624328 trmE 1176931 trmE Yersinia pestis CO92 tRNA modification GTPase TrmE YP_002348954.1 4622964 D 214092 CDS YP_002348955.1 218931080 1176932 4624514..4625713 1 NC_003143.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity; trans-2-enoyl-CoA reductase 4625713 1176932 YPO4104 Yersinia pestis CO92 trans-2-enoyl-CoA reductase YP_002348955.1 4624514 D 214092 CDS YP_002348958.1 218931083 1176935 complement(4627689..4629017) 1 NC_003143.1 xanthine/uracil permeases family protein 4629017 yieG 1176935 yieG Yersinia pestis CO92 xanthine/uracil permeases family protein YP_002348958.1 4627689 R 214092 CDS YP_002348959.1 218931084 1176936 4629510..4630178 1 NC_003143.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4630178 1176936 YPO4108 Yersinia pestis CO92 6-phosphogluconate phosphatase YP_002348959.1 4629510 D 214092 CDS YP_002348960.1 218931085 1176937 complement(4630213..4630968) 1 NC_003143.1 amino acid transport system permease 4630968 1176937 YPO4109 Yersinia pestis CO92 amino acid transport system permease YP_002348960.1 4630213 R 214092 CDS YP_002348961.1 218931086 1176938 complement(4630970..4631707) 1 NC_003143.1 ABC transporter permease 4631707 1176938 YPO4110 Yersinia pestis CO92 ABC transporter permease YP_002348961.1 4630970 R 214092 CDS YP_002348962.1 218931087 1176939 complement(4631890..4632744) 1 NC_003143.1 substrate-binding protein 4632744 1176939 YPO4111 Yersinia pestis CO92 substrate-binding protein YP_002348962.1 4631890 R 214092 CDS YP_002348963.1 218931088 1176940 complement(4632964..4633635) 1 NC_003143.1 hypothetical protein 4633635 1176940 YPO4112 Yersinia pestis CO92 hypothetical protein YP_002348963.1 4632964 R 214092 CDS YP_002348964.1 218931089 1176941 complement(4633931..4634653) 1 NC_003143.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4634653 phoU 1176941 phoU Yersinia pestis CO92 transcriptional regulator PhoU YP_002348964.1 4633931 R 214092 CDS YP_002348965.1 218931090 1176942 complement(4634741..4635517) 1 NC_003143.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4635517 pstB 1176942 pstB Yersinia pestis CO92 phosphate transporter ATP-binding protein YP_002348965.1 4634741 R 214092 CDS YP_002348966.1 218931091 1176943 complement(4635598..4636485) 1 NC_003143.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease PtsA 4636485 pstA 1176943 pstA Yersinia pestis CO92 phosphate transporter permease PtsA YP_002348966.1 4635598 R 214092 CDS YP_002348967.1 218931092 1176944 complement(4636487..4637458) 1 NC_003143.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease PstC 4637458 pstC 1176944 pstC Yersinia pestis CO92 phosphate transporter permease PstC YP_002348967.1 4636487 R 214092 CDS YP_002348968.1 218931093 1176945 complement(4637672..4638712) 1 NC_003143.1 phosphate ABC transporter substrate-binding protein PstS 4638712 pstS 1176945 pstS Yersinia pestis CO92 phosphate ABC transporter substrate-binding protein PstS YP_002348968.1 4637672 R 214092 CDS YP_002348969.1 218931094 1176946 complement(4639195..4641024) 1 NC_003143.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4641024 glmS 1176946 glmS Yersinia pestis CO92 glucosamine--fructose-6-phosphate aminotransferase YP_002348969.1 4639195 R 214092 CDS YP_002348970.1 218931095 1176947 complement(4641225..4642595) 1 NC_003143.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4642595 glmU 1176947 glmU Yersinia pestis CO92 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002348970.1 4641225 R 214092 CDS YP_002348971.1 218931096 1176948 complement(4643216..4643638) 1 NC_003143.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 4643638 atpC 1176948 atpC Yersinia pestis CO92 ATP synthase F0F1 subunit epsilon YP_002348971.1 4643216 R 214092 CDS YP_002348972.1 218931097 1176949 complement(4643660..4645042) 1 NC_003143.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 4645042 atpD 1176949 atpD Yersinia pestis CO92 ATP synthase F0F1 subunit beta YP_002348972.1 4643660 R 214092 CDS YP_002348973.1 218931098 1176950 complement(4645198..4646061) 1 NC_003143.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 4646061 atpG 1176950 atpG Yersinia pestis CO92 ATP synthase F0F1 subunit gamma YP_002348973.1 4645198 R 214092 CDS YP_002348974.1 218931099 1176951 complement(4646123..4647664) 1 NC_003143.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 4647664 atpA 1176951 atpA Yersinia pestis CO92 ATP synthase F0F1 subunit alpha YP_002348974.1 4646123 R 214092 CDS YP_002348975.1 218931100 1176952 complement(4647679..4648212) 1 NC_003143.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 4648212 atpH 1176952 atpH Yersinia pestis CO92 ATP synthase F0F1 subunit delta YP_002348975.1 4647679 R 214092 CDS YP_002348976.1 218931101 1176953 complement(4648227..4648697) 1 NC_003143.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 4648697 atpF 1176953 atpF Yersinia pestis CO92 ATP synthase F0F1 subunit B YP_002348976.1 4648227 R 214092 CDS YP_002348977.1 218931102 1176954 complement(4648759..4648998) 1 NC_003143.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 4648998 atpE 1176954 atpE Yersinia pestis CO92 ATP synthase F0F1 subunit C YP_002348977.1 4648759 R 214092 CDS YP_002348978.1 218931103 1176955 complement(4649048..4649872) 1 NC_003143.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 4649872 atpB 1176955 atpB Yersinia pestis CO92 ATP synthase F0F1 subunit A YP_002348978.1 4649048 R 214092 CDS YP_002348979.1 218931104 1176956 complement(4649912..4650295) 1 NC_003143.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4650295 atpI 1176956 atpI Yersinia pestis CO92 F0F1 ATP synthase subunit I YP_002348979.1 4649912 R 214092 CDS YP_002348980.1 218931105 1176957 complement(4650962..4651582) 1 NC_003143.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4651582 gidB 1176957 gidB Yersinia pestis CO92 16S rRNA methyltransferase GidB YP_002348980.1 4650962 R 214092 CDS YP_002348981.1 218931106 1176958 complement(4651728..4653617) 1 NC_003143.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 4653617 gidA 1176958 gidA Yersinia pestis CO92 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA YP_002348981.1 4651728 R 214092 CDS