-- dump date 20140620_141627 -- class Genbank::CDS -- table cds_note -- id note YP_068414.1 similar to Y. pestis YPCD1.72c YP_068415.1 similar to Y. pestis YPCD1.73c YP_068416.1 similar to Y. pestis YPCD1.14c YP_068418.2 RepA YP_068420.1 similar to Y. pestis YPCD1.79c YP_068421.1 identical to Y. pestis YPCD1.81 YP_068422.1 similar to Y. pestis YPCD1.83c YP_068423.1 similar to Y. pestis YPCD1.84c YP_068424.1 identical to C-term of Y. pestis YPCC1.85 YP_068427.1 similar to Y. pestis YPCD1.90c YP_068428.1 identical to Y. pestis YPCD1.91 YP_068429.1 identical to Y. pestis YPCD1.93 YP_068430.1 similar to Y. pestis YPCD1.94 YP_068431.1 similar to Y. pestis YPCD1.95c YP_068432.1 similar to Y. pestis YPCD1.96c YP_068433.1 similar to fusion of Y.pestis YPCD1.03c and YPCD1.97c YP_068434.1 similar to Y. pestis YPCD1.04 YP_068435.1 similar to Y. pestis YPCD1.05c YP_068436.1 identical to Y. pestis YPCD1.06 YP_068437.1 similar to Y. pestis YPCD1.08c YP_068438.1 similar to Y. pestis YPCD1.09c YP_068439.1 similar to Y. pestis YPCD1.10c YP_068442.1 SopB YP_068443.2 similar to Y. pestis YPCD1.13c YP_068445.1 similar to Y. pestis YPCD1.14c YP_068446.1 similar to Y. pestis YPCD1.15c YP_068447.1 similar to Y. pestis YPCD1.85 YP_068448.1 similar to Y. pestis YPCD1.18c YP_068449.1 similar to Y. pestis YPCD1.19c, yopK, yopQ, probable virulence determinant protein YP_068450.1 similar to Y. pestis YPCD1.20 YP_068451.1 similar to Y. pestis YPCD1.21 YP_068452.1 similar to Y. pestis YPCD1.24c YP_068453.1 similar to Y. pestis YPCD1.23 YP_068454.1 similar to Y. pestis YPCD1.24c YP_068455.1 similar to Y. pestis YPCD1.25 YP_068456.1 similar to Y. pestis YPCD1.26c YP_068460.1 similar to Y. pestis Y0056, similar to Y. intermedia transposase YP_068461.1 similar to N-term Y. pestis YPCD1.24c, possible transposase remnant YP_068463.1 similar to Y. pestis YPCD1.28c YP_068464.1 similar to Y. pestis YPCD1.29c YP_068465.1 similar to Y. pestis YPCD1.30c YP_068466.1 similar to Y. pestis YPCD1.31c YP_068467.1 similar to Y. pestis YPCD1.32c YP_068468.1 similar to Y. pestis YPCD1.33c YP_068469.1 similar to Y. pestis YPCD1.34c YP_068470.1 similar to Y. pestis YPCD1.35c YP_068471.1 similar to Y. pestis YPCD1.36c YP_068472.1 similar to Y. pestis YPCD1.37c YP_068473.1 similar to Y. pestis YPCD1.38c YP_068474.1 similar to Y. pestis YPCD1.39c YP_068476.1 identical to Y. pestis YPCD1.40 YP_068477.1 identical to Y. pestis YPCD1.41 YP_068478.2 similar to Y. pestis YPCD1.42 YP_068479.1 identical to Y. pestis YPCD1.43 YP_068480.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_068481.1 identical to Y. pestis YPCD1.45 YP_068482.1 identical to Y. pestis YPCD1.46 YP_068483.1 identical to Y. pestis YPCD1.47 YP_068484.1 similar to Y. pestis YPCD1.48 YP_068485.1 identical to Y. pestis YPCD1.49 YP_068486.1 similar to Y. pestis YPCD1.50 YP_068487.1 identical to Y. pestis YPCD1.51 YP_068488.1 similar to Y. pestis YPCD1.52 YP_068489.1 similar to Y. pestis YPCD1.53 YP_068490.1 similar to Y. pestis YPCD1.54 YP_068491.1 identical to Y. pestis YPCD1.55 YP_068492.1 similar to Y. pestis YPCD1.56 YP_068493.1 similar to Y. pestis YPCD1.57 YP_068494.1 identical to Y. pestis YPCD1.58 YP_068495.1 similar to Y. pestis YPCD1.59 YP_068496.1 identical to Y. pestis YPCD1.60 YP_068497.1 similar to Y. pestis YPCD1.61 YP_068498.1 identical to Y. pestis YPCD1.62 YP_068499.1 identical to Y. pestis YPCD1.63 YP_068500.1 similar to Y. pestis YPCD1.64 YP_068501.1 similar to Y. pestis YPCD1.65 YP_068502.1 similar to Y. pestis YPCD1.66 YP_068503.1 similar to Y. pestis YPCD1.67c YP_068504.1 similar to Y. pestis YPCD1.69 YP_068505.1 similar to Y. pestis YPCD1.70c YP_068507.1 similar to Y. pestis YPCD1.71c YP_068509.1 similar to Q7X3W4 RepA. Erwinia sp. Ejp 556. Score = 326 bits (835), Expect = 3e-88 Identities = 160/324 (49%) YP_068512.1 similar to CAD58562 TriA protein. Yersinia enterocolitica. Score = 254 bits (649), Expect = 5e-67 Identities = 128/221 (57%) YP_068513.1 similar to CAD58563 TriB protein. Yersinia enterocolitica. Score = 97.4 bits (241), Expect = 3e-20 Identities = 49/94 (52%) YP_068514.1 similar to CAD58564 TriC protein. Yersinia enterocolitica. Score = 1244 bits (3218), Expect = 0.0 Identities = 594/915 (64%) YP_068515.1 similar to CAD58565 TriD protein. Yersinia enterocolitica. Score = 227 bits (578), Expect = 1e-58 Identities = 124/242 (51%) YP_068516.1 Antitoxin that counteracts the effect of the YoeB toxin YP_068517.1 similar to P56605 Hypothetical protein yoeB. Escherichia coli, and Shigella flexneri. Score = 154 bits (389), Expect = 3e-37 Identities = 67/84 (79% YP_068518.1 similar to Q9RPN3 ORF4. Yersinia pestis. Score = 63.2 bits (152), Expect = 8e-10 Identities = 32/74 (43% YP_068519.1 similar to CAD58566 TriE protein. Yersinia enterocolitica. Score = 295 bits (756), Expect = 5e-79 Identities = 150/332 (45%) YP_068520.1 similar to CAD58568 TriG protein. Yersinia enterocolitica. Score = 286 bits (733), Expect = 1e-76 Identities = 138/227 (60%); VirB8 YP_068521.1 similar to CAD58569 TriH protein. Yersinia enterocolitica. Score = 357 bits (915), Expect = 2e-97 Identities = 175/292 (59% YP_068522.1 similar to CAD58570 TriI protein. Yersinia enterocolitica. Score = 387 bits (993), Expect = e-106 Identities = 206/415 (49%) YP_068523.1 similar to CAD58571 TriJ protein. Yersinia enterocolitica. Score = 507 bits (1305), Expect = e-142 Identities = 241/335 (71%) YP_068524.1 similar to CAD58572 Hypothetical protein ORF29. Yersinia enterocolitica. Score = 136 bits (343), Expect = 4e-32 Identities = 66/134 (49%) YP_068525.1 similar to Q9F518 YggA protein. Escherichia coli. Score = 81.3 bits (199), Expect = 3e-15 Identities = 39/85 (45%) YP_068526.1 similar to Q8ZGB6 Putative exported protein (Putative outer membrane protein). Yersinia pestis. Score = 250 bits (639), Expect = 2e-65 Identities = 158/406 (38%) YP_068528.1 similar to CAD58574 DNA binding protein. Yersinia enterocolitica. Score = 97.4 bits (241), Expect = 3e-20 Identities = 55/135 (40%); IPR001801 Histone-like nucleoid-structuring protein H-NS YP_068536.1 similar to CAD58575 TriK protein. Yersinia enterocolitica. Score = 870 bits (2248), Expect = 0.0 Identities = 430/590 (72%) YP_068537.1 similar to CAD58576 TriL protein. Yersinia enterocolitica. Score = 327 bits (837), Expect = 1e-88 Identities = 158/234 (67%) YP_068538.1 similar to CAD58573 Topoisomerase. Yersinia enterocolitica. Score = 848 bits (2191), Expect = 0.0 Identities = 443/740 (59%) YP_068542.1 similar to CAD58578 Antirestriction protein. Yersinia enterocolitica. Score = 457 bits (1176), Expect = e-128 Identities = 227/323 (70%) YP_068543.1 similar to CAE15300 Hypothetical gene. Photorhabdus luminescens subsp. laumondii TTO1. Score = 68.9 bits (167), Expect = 1e-11 Identities = 36/65 (55%)none YP_068544.1 similar to AB070224 parA partitioning protein [Serratiamarcescens] Expect = 9e-90 Identities = 172/209 (82%); IPR000707 ATPase, ParA type YP_068545.1 similar to hypothetical proteins from several shuttle vectors, e.g. AF118810 Shuttle vector pME6010;Expect = 6e-19 Identities = 48/70 (68%) YP_068551.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_068552.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_068553.1 catalyzes the formation of asparagine from aspartate and ammonia YP_068554.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_068555.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_068556.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_068557.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_068558.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_068559.1 not present in pestis YP_068560.1 similar to Yersinia pestis YPO0009 membrane transport protein (100% evalue=0); Salmonella typhimurium STM3887 yieO; MFS family tranport protein (1st mdule) (74% evalue=0) YP_068561.1 similar to Yersinia pestis YPO0010 GntR-famly transcriptional regulator (100% evalue=1.E-128); Escherichia coli Z5258 yieP; orf; Unknown function (67.6% evalue=5.E-85) YP_068562.1 similar to Yersinia pestis YPO1583 transposase for the IS285 insertion element (99.7% evalue=0) YP_068563.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_068564.1 similar to Yersinia pestis YPO0013a conserved hypothetical protein (100% evalue=3.E-46); Escherichia coli b3858 yihD; hypothetical 10.3 kD protein in mobA-dsbA intergenic region (O89) (76.4% evalue=2.E-35) YP_068565.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_068566.1 similar to Yersinia pestis YPO0015 dsbA; secreted thiol:disulfide interchange protein DsbA (100% evalue=1.E-116); Salmonella typhimurium STM3997 dsbA; periplasmic protein disulfide isomerase I (75.8% evalue=1.E-88) YP_068567.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_068568.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_068569.1 similar to Yersinia pestis YPO0020 conserved hypothetical protein (100% evalue=1.E-103); Salmonella typhi STY3878 yihI; conserved hypothetical protein (51.9% evalue=1.E-43) YP_068570.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_068571.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_068572.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_068573.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_068574.1 similar to Yersinia pestis YPO0026 bipA, typA; GTPase (99.8% evalue=0); Salmonella typhimurium STM4009 typA; GTP-binding elongation factor family protein (89.1% evalue=0) YP_068575.1 similar to Yersinia pestis YPO0027 conserved hypothetical protein (100% evalue=1.E-110); Salmonella typhi STY3852 yihX; haloacid dehalogenase-like hydrolase (70.2% evalue=6.E-75) YP_068576.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_068577.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_068578.1 similar to Yersinia pestis YPO0032 conserved membrane protein (100% evalue=1.E-178); Escherichia coli b3888 yiiD; hypothetical 37.1 kD protein in rbn-fdhE intergenic region (O329) (83.8% evalue=1.E-149) YP_068579.1 similar to Yersinia pestis YPO0033 possible exported protein (100% evalue=0); Escherichia coli b3655 yicH; hypothetical 62.3 kD protein in gltS-selC intergenic region (49% evalue=1.E-164) YP_068580.1 similar to Yersinia pestis YPO0034 membrane permease (99.3% evalue=0); Escherichia coli ECs4530 transport protein (84.4% evalue=0) YP_068581.1 similar to Yersinia pestis YPO0035 gltS, gltC; sodium/glutamate symport carrier protein (100% evalue=0); Escherichia coli ECs4529 glutamate transport protein (82.4% evalue=0) YP_068582.1 catalyzes branch migration in Holliday junction intermediates YP_068583.1 specifically modifies tRNA at position G18 YP_068584.1 similar to Yersinia pestis YPO0038 spoT; guanosine-3',5'-bisbis(diphosphate) 3'-pyrophosphydrolase (99.8% evalue=0); Escherichia coli JW3625 spoT; Guanosine 3',5'-bis(diphosphate) 3'-pyrophosphatase (91.4% evalue=0) YP_068585.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_068586.1 Essential for recycling GMP and indirectly, cGMP YP_068587.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_068588.1 similar to Yersinia pestis YPO0042 membrane protein (99.4% evalue=2.E-98); Escherichia coli b3646 yicG; hypothetical 22.0 kD protein in rph-gmk intergenic region precursor (73.6% evalue=2.E-82) YP_068589.1 similar to Yersinia pestis YPO0043 conserved hypothetical protein (100% evalue=1.E-157); Salmonella typhi STY4059 conserved hypothetical protein (87.8% evalue=1.E-140) YP_068590.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_068591.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_068592.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_068593.1 catalyzes the formation of dUMP from dUTP YP_068594.2 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_068595.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_068596.1 required for 70S ribosome assembly YP_068597.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_068598.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_068599.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_068600.1 similar to Yersinia pestis YPO0054 kdtX, waaE; lipopolysaccharide core biosynthesis glycosyl transferase (100% evalue=1.E-149); Vibrio cholerae VC0224 lipopolysaccharide biosynthesis glycosyltransferase, (52.2% evalue=6.E-66) YP_068601.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_068602.1 similar to Yersinia pestis YPO0056 rfaC, waaC, rfa-2; lipopolysaccharide heptosyltransferase-1 (100% evalue=0); Escherichia coli b3621 rfaC, rfa-2; lipopolysaccharide heptosyltransferase-1 (68.3% evalue=1.E-127) YP_068603.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_068604.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_068605.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_068606.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_068607.1 similar to Salmonella typhi STY4089 exported protein (63.6% evalue=1.E-106); Salmonella typhimurium STM3706 yigQ; periplasmic protein (64% evalue=1.E-105) YP_068608.2 similar to Yersinia pestis YPO0063 membrane protein (99.5% evalue=0); Salmonella typhimurium STM3705 yibP; paral membrane protein (65.7% evalue=1.E-150) YP_068609.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_068610.1 similar to Yersinia pestis YPO0065 membrane protein (100% evalue=1.E-76); Salmonella typhi STY4092 secreted protein (67.8% evalue=2.E-52) YP_068611.1 similar to Yersinia pestis YPO0066 grxC; glutaredoxin (100% evalue=3.E-43); Salmonella typhi STY4093 grxC; glutaredoxin 3 (85.3% evalue=5.E-36) YP_068612.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_068613.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_068614.1 similar to Yersinia pestis YPO0069 hypothetical protein. YP_068615.1 catalyzes the O-acetylation of serine YP_068616.1 similar to Yersinia pestis YPO0071 methyltransferase (99.3% evalue=1.E-90); Escherichia coli JW3581 yibK; Hypothetical tRNA/rRNA methyltransferase (79.6% evalue=2.E-71) YP_068617.1 similar to Yersinia pestis YPO0072 bifunctional regulatory protein/DNA repair protein (98.5% evalue=0); Ralstonia solanacearum RS00768 ada, RSc2570; methylated-DNA-protein-cysteine methyltransferase O-6-methylguanine-DNA transcription regulator (64.8% evalue=1.E-127) YP_068618.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_068619.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_068620.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates YP_068621.1 similar to Yersinia pestis YPO0076 conserved hypothetical protein (99.6% evalue=0); Salmonella typhimurium PSLT051 samB; cytoplasmic protein (62% evalue=1.E-108) YP_068622.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_068623.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_068624.1 similar to Yersinia pestis YPO0079 sbp1; exported sulfate-binding protein (98.7% evalue=0); Escherichia coli JW3888 sbp; Periplasmic sulphate binding protein (83.5% evalue=1.E-162) YP_068625.1 similar to Yersinia pestis YPO0080 hypothetical protein (99.6% evalue=1.E-137); Bacillus subtilis BG14094 yvgL, yvsD; molybdate transport system substrate-binding protein (21.9% evalue=9.E-09) YP_068626.1 similar to Yersinia pestis YPO0081 membrane transport protein (100% evalue=0); Escherichia coli ECs0798 membrane pump protein (52.2% evalue=1.E-142) YP_068627.1 similar to Yersinia pestis YPO0082 possible transferase (100% evalue=1.E-131); Sinorhizobium meliloti SMc00502 conserved hypothetical protein (58.1% evalue=3.E-70) YP_068628.1 similar to Yersinia pestis YPO0083 hypothetical protein (100% evalue=1.E-142); Sinorhizobium meliloti SMc00503 conserved hypothetical protein (65.4% evalue=3.E-89) YP_068629.1 similar to Yersinia pestis YPO0084 possible transcriptional regulator (99.1% evalue=0); Sinorhizobium meliloti SMc00504 transcription regulator protein (26.3% evalue=9.E-34) YP_068630.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_068631.1 similar to Yersinia pestis YPO0086 exported protein (99.5% evalue=1.E-114); Salmonella typhi STY3788 yiiQ; conserved hypothetical protein (57.2% evalue=2.E-54) YP_068632.1 similar to Yersinia pestis YPO0087 conserved membrane protein (100% evalue=2.E-84); Escherichia coli b3921 yiiR; hypothetical 16.5 kD protein in tpiA-fpr intergenic region (O146) (66.6% evalue=3.E-55) YP_068633.1 similar to Yersinia pestis YPO0088 fpr, mvrA; ferredoxin--NADP reductase (100% evalue=1.E-141); Salmonella typhi STY3786 fpr; ferredoxin--NADP reductase (77% evalue=1.E-110) YP_068634.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_068635.1 similar to Escherichia coli b3926 glpK; glycerol kinase (84.6% evalue=0); Escherichia coli Z5471 glpK; glycerol kinase (84.4% evalue=0) YP_068636.1 similar to Yersinia pestis YPO0091 glpF; glycerol uptake facilitator protein (100% evalue=1.E-160); Escherichia coli ECs4852 glycerol facilitator protein (82.6% evalue=1.E-136) YP_068637.1 similar to Yersinia pestis YPO0092 hypothetical protein YP_068638.1 similar to Yersinia pestis YPO0093 conserved hypothetical protein (100% evalue=1.E-37); Salmonella typhimurium STM4088 yiiU; cytoplasmic protein (77.2% evalue=4.E-27) YP_068639.1 similar to Xylella fastidiosa XF1220 colicin V secretion ABC transporter ATP-binding protein (43.6% evalue=1.E-163); Pseudomonas aeruginosa PA4143 probable toxin transporter (44.9% evalue=1.E-172) YP_068640.1 similar to Yersinia pestis YPO0099 exported protein (99.7% evalue=0); Pseudomonas aeruginosa PA4142 probable secretion protein (25.6% evalue=4.E-41) YP_068641.1 similar to Yersinia pestis YPO0100 hypothetical protein (98.7% evalue=4.E-37) YP_068642.1 similar to Yersinia pestis YPO0101 hypothetical protein. 100% identical YP_068643.1 similar to Yersinia pestis YPO0102 exported protein (100% evalue=1.E-106) YP_068644.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_068645.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_068646.1 heat shock protein involved in degradation of misfolded proteins YP_068647.1 heat shock protein involved in degradation of misfolded proteins YP_068648.1 similar to Yersinia pestis YPO0107 ftsN, msgA; cell division protein (99.6% evalue=1.E-160); Salmonella typhimurium STM4093 ftsN; essential cell division protein (51% evalue=2.E-77) YP_068649.2 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_068650.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_068651.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_068652.1 similar to Yersinia pestis YPO0112 conserved hypothetical protein (100% evalue=2.E-81); Ralstonia solanacearum RS01011 hypothetical transmembrane protein (57.5% evalue=2.E-45) YP_068653.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_068654.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_068655.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_068656.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_068657.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_068658.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_068659.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_068660.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_068661.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_068662.1 similar to Yersinia pestis YPO3923 TonB dependent receptor protein (99.5% evalue=0); Pseudomonas aeruginosa PA3408 hasR; heme acquisition protein HasR (45.7% evalue=0) YP_068663.1 similar to Yersinia pestis YPO3922 hemophore HasA (98.5% evalue=1.E-115); Pseudomonas aeruginosa PA3407 hasAp; heme acquisition protein HasAp (30.3% evalue=9.E-18) YP_068664.1 similar to Yersinia pestis YPO3920 ABC transporter protein (99.6% evalue=0); Pseudomonas aeruginosa PA3406 hasD; transport protein HasD (58.4% evalue=0) YP_068665.1 similar to Yersinia pestis YPO3919 HlyD family secretion protein (98.8% evalue=0); Pseudomonas aeruginosa PA3405 hasE; metalloprotease secretion protein (43.6% evalue=1.E-93) YP_068666.1 similar to Yersinia pestis YPO3918 membrane protein (98.8% evalue=1.E-147); C. jejuni Cj0181 tonB1; possible tonB transport protein (34.8% evalue=3.E-18) YP_068667.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide YP_068668.1 similar to Yersinia pestis YPO3916 peroxiredoxin/glutaredoxin family protein (100% evalue=1.E-141); Vibrio cholerae VC2637 peroxiredoxin family protein/glutaredoxin (81.3% evalue=1.E-117) YP_068669.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_068670.1 catalyzes the conversion of NADPH to NADH YP_068671.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_068672.1 similar to Yersinia pestis YPO3912 yijD; membrane protein (100% evalue=3.E-71); Salmonella typhimurium STM4128 yijD; inner membrane protein (70.7% evalue=1.E-41) YP_068673.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_068674.2 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_068675.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_068676.1 similar to Yersinia pestis YPO3908 periplasmic protein precursor (99.6% evalue=1.E-175); Escherichia coli JW4186 ytfQ; Hypothetical ABC transporter periplasmic binding protein (75.7% evalue=1.E-134) YP_068677.1 similar to Yersinia pestis YPO3907 sugar transport system ATP-binding protein (99.7% evalue=0); Escherichia coli Z5839 ATP-binding component of ABC transporter (67.4% evalue=0) YP_068678.1 similar to Yersinia pestis YPO3906 sugar transport system permease (100% evalue=0); Escherichia coli Z5840 ytfT; transport system permease (70.3% evalue=1.E-122) YP_068679.1 membrane component of a sugar ABC transporter system YP_068680.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_068681.1 similar to Yersinia pestis YPO3903 conserved hypothetical protein (100% evalue=3.E-62); Escherichia coli JW3737 yifE; Hypothetical protein (83% evalue=1.E-52) YP_068682.1 similar to Yersinia pestis YPO3902 magnesium chelatase family protein (99.8% evalue=0); Salmonella typhimurium STM3899 yifB; magnesium chelatase, subunit ChlI (62.7% evalue=0) YP_068683.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_068684.1 similar to Yersinia pestis YPO3900 ilvM; acetolactate synthase isozyme II small subunit (100% evalue=1.E-41); Escherichia coli Z5280 ilvM; acetolactate synthase II, valine insensitive, small subunit (67.8% evalue=2.E-24) YP_068685.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_068686.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_068687.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_068688.1 similar to Yersinia pestis YPO3935 membrane protein (72.7% evalue=2.E-63) YP_068689.1 similar to Yersinia pestis YPO3894 membrane protein (82.4% evalue=2.E-70) YP_068690.1 similar to Yersinia pestis YPO3894 membrane protein (94.7% evalue=5.E-83) YP_068691.1 similar to Yersinia pestis YPO3983 conserved hypothetical protein (49.6% evalue=1.E-72) YP_068692.1 similar to Yersinia pestis YPO3890 hypothetical protein. 100% identical YP_068693.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_068694.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_068695.1 similar to Yersinia pestis YPO3885 hypothetical protein (100% evalue=4.E-45) YP_068696.1 similar to Yersinia pestis YPO3883 imm; colicin immunity protein (49.4% evalue=1.E-21); Salmonella typhi STY3281 bacteriocin immunity protein (44.1% evalue=2.E-16) YP_068697.1 similar to Yersinia pestis YPO3884 colicin (partial) (48% evalue=1.E-15); Pseudomonas aeruginosa PA1150 pys2; pyocin S2 (47.4% evalue=4.E-35) YP_068698.1 similar to Yersinia pestis YPO3883 imm; colicin immunity protein (51.9% evalue=2.E-19); Pseudomonas aeruginosa PA1151 imm2; pyocin S2 immunity protein (60.4% evalue=6.E-23) YP_068699.1 similar to Yersinia pestis YPO3884 colicin (partial) (55.5% evalue=3.E-19); Pseudomonas aeruginosa PA1150 pys2; pyocin S2 (48.2% evalue=5.E-31) YP_068700.1 similar to Yersinia pestis YPO3883 imm; colicin immunity protein (50.5% evalue=5.E-19); Salmonella typhi STY3281 bacteriocin immunity protein (58.8% evalue=6.E-23) YP_068701.1 similar to Yersinia pestis YPO1234 probable phage antitermination protein Q (52.9% evalue=3.E-27); Salmonella typhimurium STM2239 phage protein; homology to antiterminator protein Q of phage P5 (40% evalue=4.E-19) YP_068702.1 not present in pestis YP_068703.1 similar to Yersinia pestis YPO3881 chaperone protein (99.5% evalue=1.E-137); Pseudomonas aeruginosa PA2132 probable pili assembly chaperone (46.4% evalue=2.E-43) YP_068704.1 similar to Yersinia pestis YPO3880 exported protein (100% evalue=0); Pseudomonas aeruginosa PA2131 hypothetical protein (44.6% evalue=9.E-94) YP_068705.1 similar to Yersinia pestis YPO3879 outer membrane usher protein (98.8% evalue=0); Pseudomonas aeruginosa PA2130 probable fimbrial biogenesis usher protein (46.7% evalue=0) YP_068706.1 similar to Yersinia pestis YPO3878 fimbrial chaperone (99.5% evalue=1.E-134); Pseudomonas aeruginosa PA2129 probable pili assembly chaperone (44.1% evalue=3.E-49) YP_068707.1 similar to Yersinia pestis YPO3877 fimbrial protein (100% evalue=8.E-93); Salmonella typhimurium STM0340 stbA; fimbriae; major subunit (49.1% evalue=2.E-37) YP_068708.1 similar to Yersinia pestis YPO3874 exported protein (99.6% evalue=1.E-151); Caulobacter crescentus CC2650 glutamine cyclotransferase (37.6% evalue=5.E-42) YP_068709.1 similar to Yersinia pestis YPO3873 ppiC; peptidyl-prolyl cis-trans isomerase C (100% evalue=2.E-49); Escherichia coli JW3748 ppiC; peptidyl-prolyl cis/trans isomerases (67.7% evalue=4.E-31) YP_068710.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_068711.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_068712.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_068713.1 similar to Yersinia pestis YPO3868 trxA, tsnC, fipA; thioredoxin 1 (100% evalue=2.E-57); Escherichia coli JW3754 trxA; Thioredoxin (87% evalue=2.E-51) YP_068714.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_068715.1 similar to Yersinia pestis YPO3866 rfe; undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase (100% evalue=0); Escherichia coli ECs4717 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (80.9% evalue=1.E-166) YP_068716.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_068717.1 similar to Yersinia pestis YPO3864 rffE, wecB, nfrC; UDP-N-acetylglucosamine 2-epimerase (99.7% evalue=0); Escherichia coli ECs4719 UDP-N-acetyl glucosamine -2-epimerase (78.6% evalue=1.E-172) YP_068718.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_068719.1 similar to Yersinia pestis YPO3862 rffG; dTDP-D-glucose-4,6-dehydratase (99.4% evalue=0); Salmonella typhimurium STM3922 rffG; dTDP-glucose 4,6-dehydratase (83% evalue=1.E-175) YP_068720.1 similar to Yersinia pestis YPO3861 rffH; glucose-1-phosphate thymidylyltransferase (100% evalue=1.E-169); Escherichia coli b3789 rffH; glucose-1-phosphate thymidylyltransferase (dtdp-glucose synthase) (dtdp-glucose pyrophosphorylase) (86.6% evalue=1.E-148) YP_068721.1 similar to Yersinia pestis YPO3860 rffC, wecD; lipopolysaccharide biosynthesis protein (97.2% evalue=1.E-120); Escherichia coli JW3764 yifH; Hypothetical protein (49.2% evalue=6.E-44) YP_068722.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_068723.1 similar to Yersinia pestis YPO3858 wzxE, wzx; lipopolysaccharide biosynthesis protein (99.7% evalue=0); Salmonella typhi STY3629 lipopolysaccharide biosynthesis protein (75% evalue=0) YP_068724.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_068725.1 enterobacterial common antigen polymerase YP_068726.1 similar to Yersinia pestis YPO3855 wecG, rffM; probable UDP-N-acetyl-D-mannosaminuronic acid transferase (99.5% evalue=1.E-140); Escherichia coli b3794 wecg, rffM; (UDP-mannaca transferase) (71.1% evalue=1.E-101) YP_068727.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_068728.1 similar to Yersinia pestis YPO3852 hemY; protoheme IX biogenesis protein (99.7% evalue=0); Escherichia coli Z5316 hemY; a late step of protoheme IX synthesis (70.6% evalue=1.E-163) YP_068729.1 similar to Yersinia pestis YPO3851 hemX; uroporphyrin-III C-methyltransferase (99.7% evalue=0); Escherichia coli JW3775 hemX; uroporphyrin-III C-methyltransferase (68.1% evalue=1.E-135) YP_068730.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_068731.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_068732.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_068733.1 similar to Yersinia pestis YPO1583 transposase for the IS285 insertion element (100% evalue=0) YP_068734.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_068735.1 similar to Yersinia pestis YPO3846 lipoprotein. 90% identical YP_068736.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_068737.1 similar to Yersinia pestis YPO3844 conserved hypothetical protein (100% evalue=1.E-130); Escherichia coli b3810 yigA; hypothetical 26.7 kD protein in dapF-xerC intergenic region (ORF 235) (67.5% evalue=3.E-83) YP_068738.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_068739.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_068740.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_068741.1 similar to Yersinia pestis YPO3840 TetR-family regulatory protein (96% evalue=1.E-118); Mesorhizobium loti mll3386 transcriptional regulator (47.8% evalue=9.E-43) YP_068742.1 similar to Yersinia pestis YPO3839 conserved hypothetical protein (98.7% evalue=0); Sinorhizobium meliloti SMa1334 conserved hypothetical protein (55.7% evalue=1.E-121) YP_068743.1 similar to Yersinia pestis YPO3838 conserved hypothetical protein (100% evalue=1.E-161); Sinorhizobium meliloti SMa1332 conserved hypothetical protein (71.6% evalue=1.E-109) YP_068744.1 responsible for the influx of magnesium ions YP_068745.1 similar to Yersinia pestis YPO3836 rarD; membrane protein (100% evalue=1.E-168); Salmonella typhimurium STM3955 rarD; chloramphenicol resistance (75.7% evalue=1.E-129) YP_068746.1 similar to Yersinia pestis YPO3835 conserved hypothetical protein (100% evalue=2.E-83); Escherichia coli b3820 yigI; hypothetical 17.1 kD protein in rarD-pldA intergenic region (66.8% evalue=2.E-55) YP_068747.1 catalyzes the hydrolysis of phosphatidylcholine YP_068748.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_068749.1 similar to Yersinia pestis YPO3832 rhtC; threonine efflux protein (100% evalue=1.E-116); Salmonella typhi STY3600 rhtC; threonine efflux protein (72.3% evalue=2.E-85) YP_068750.1 similar to Yersinia pestis YPO3831 rhtB; homoserine/homoserine lactone efflux protein (100% evalue=1.E-111); Escherichia coli ECs4754 homoserine/homoserine lactone effulux protein (75.4% evalue=5.E-88) YP_068751.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_068752.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_068753.1 similar to Yersinia pestis YPO3828 hypothetical protein (99.7% evalue=0) YP_068754.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_068755.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_068756.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_068757.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_068758.1 similar to Yersinia pestis YPO3823 dcrB; lipoprotein (100% evalue=1.E-92); Salmonella typhimurium STM3580 inner membrane lipoprotein (58.6% evalue=5.E-56) YP_068759.1 similar to Yersinia pestis YPO3822 yhhQ; membrane protein (99.5% evalue=1.E-123); Salmonella typhimurium STM3579 yhhQ; integral membrane protein (75.2% evalue=1.E-90) YP_068760.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_068761.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_068762.1 similar to Yersinia pestis YPO3819 yhhN; membrane protein (100% evalue=1.E-117); Escherichia coli ECs4317 enzyme (66.8% evalue=4.E-78) YP_068763.1 similar to Yersinia pestis YPO3818 conserved hypothetical protein (100% evalue=2.E-55); Pseudomonas aeruginosa PA3979 hypothetical protein (45.6% evalue=1.E-21) YP_068764.1 similar to Yersinia pestis YPO3817 membrane protein (100% evalue=2.E-73); Salmonella typhimurium STM3574 yhhM; inner membrane protein (38.4% evalue=2.E-17) YP_068765.1 similar to Yersinia pestis YPO3816a yhhL; membrane protein (100% evalue=5.E-48); Escherichia coli b3466 yhhL; hypothetical 10.3 kD protein in ftsY-nikA intergenic region (64.2% evalue=2.E-25) YP_068766.1 catalyzes the methylation of 16S rRNA at position G966 YP_068767.1 similar to Yersinia pestis YPO3814 ftsY; cell division protein (93.2% evalue=0); Escherichia coli JW3429 ftsY; signal recognition particle (ffh and ffs) receptor (60.9% evalue=1.E-167) YP_068768.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_068769.1 ABC transporter, membrane protein YP_068770.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_068771.1 similar to Yersinia pestis YPO3809 yhhK; acetyltransferase (99.2% evalue=4.E-72); Salmonella typhi STY4247 yhhK; conserved hypothetical protein (45.3% evalue=2.E-24) YP_068772.1 similar to Yersinia pestis YPO3808 livK, livJ; branched-chain amino acid-binding protein (99.4% evalue=0); Escherichia coli Z4829 livK; high-affinity leucine-specific transport system; periplasmic binding protein (75.3% evalue=1.E-165) YP_068773.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_068774.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_068775.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_068776.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_068777.1 similar to Yersinia pestis YPO3803 hypothetical protein (86.2% evalue=7.E-72) YP_068778.1 similar to Yersinia pestis YPO3802 exported protein (81.2% evalue=1.E-177) YP_068779.1 similar to Yersinia pestis YPO3801 exported protein (99.4% evalue=3.E-96) YP_068780.1 similar to Yersinia pestis YPO3800 exported protein (96.7% evalue=1.E-117) YP_068781.1 similar to Yersinia pestis YPO3800 exported protein (35.5% evalue=3.E-22) YP_068782.1 similar to Yersinia pestis YPO3798 exported protein (99.2% evalue=0) YP_068783.1 similar to Yersinia pestis YPO3797 exported protein (100% evalue=5.E-85) YP_068784.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_068785.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_068786.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_068787.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_068788.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_068789.1 similar to Yersinia pestis YPO3791 membrane protein (99.6% evalue=1.E-165); Agrobacterium tumefaciens AGR_C_121 MdcF (27.6% evalue=1.E-34) YP_068790.1 not present in pestis YP_068791.1 similar to Staphylococcus aureus_Mu50 SAV0141 hypothetical protein (25.8% evalue=1.E-26); Staphylococcus aureus_N315 SA0142 hypothetical protein, similar to DNA-binding protein (25.8% evalue=1.E-26) YP_068792.1 similar to Yersinia pestis YPO3790 yigM; membrane protein (99.6% evalue=1.E-175); Escherichia coli JW3803 yigM; Hypothetical protein (73.7% evalue=1.E-129) YP_068793.1 similar to Yersinia pestis YPO3789 metR; lysR-family transcriptional regulatory protein (99.6% evalue=0); Escherichia coli b3828 metR; transcriptional activator protein metR (88.5% evalue=1.E-159) YP_068794.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_068795.1 similar to Yersinia pestis YPO3787 carboxymethylenebutenolidase (99.6% evalue=1.E-159); Escherichia coli ECs4760 carboxymethylenebutenolidase (71.3% evalue=1.E-108) YP_068796.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_068797.1 similar to Yersinia pestis YPO3785 conserved hypothetical protein (96.5% evalue=1.E-155); C. perfringens CPE1952 ptp; protein-tyrosine phosphatase (30% evalue=2.E-31) YP_068798.1 similar to Yersinia pestis YPO3784 carbon starvation protein (100% evalue=0); Bacillus subtilis BG11924 cstA; carbon starvation protein (71% evalue=0) YP_068799.1 similar to Yersinia pestis YPO3783 membrane protein (97.7% evalue=1.E-100); Mesorhizobium loti mll0121 hypothetical protein (46.2% evalue=5.E-34) YP_068800.1 similar to Yersinia pestis YPO3782 rumC; DNA recombination protein (99.7% evalue=0); Salmonella typhi STY3590 yigN; membrane protein (73.5% evalue=1.E-173) YP_068801.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_068802.1 similar to Yersinia pestis YPO3780 conserved hypothetical protein (100% evalue=1.E-113); Salmonella typhimurium STM3971 yigP; inner membrane protein (56.8% evalue=3.E-57) YP_068803.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_068804.1 similar to Yersinia pestis YPO3778 tatA, mtta1; Sec-independent protein translocase TatA (100% evalue=6.E-44); Escherichia coli Z5358 tatA; twin arginine translocation protein; sec-independent protein export (64.1% evalue=7.E-21) YP_068805.1 similar to Yersinia pestis YPO3777 tatB, mtta2; Sec-independent protein translocase TatB (99% evalue=1.E-117); Salmonella typhimurium STM3974 tatB; component of Sec-independent protein secretion pathway (64.3% evalue=8.E-50) YP_068806.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_068807.1 magnesium dependent; not involved in the Sec-independent protein export system YP_068808.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_068809.1 similar to Yersinia pestis YPO3770 rfaH, hlyT, sfrB; regulatory protein (99.3% evalue=8.E-89); Escherichia coli b3842 rfaH, hlyT, sfrB; transcriptional activator rfaH (64.5% evalue=1.E-58) YP_068810.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_068811.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_068812.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_068813.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_068814.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_068815.1 similar to Escherichia coli ECs4776 hypothetical protein (64.8% evalue=4.E-71); Escherichia coli Z5370 yigZ; orf, hypothetical protein (64.8% evalue=4.E-71) YP_068816.1 similar to Yersinia pestis YPO3762 trkH; Trk system potassium uptake protein TrkH (100% evalue=0); Escherichia coli ECs4777 potassium uptake protein (88.6% evalue=0) YP_068817.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_068818.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_068819.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_068820.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_068821.1 similar to Yersinia pestis YPO3757 acetyltransferase (99.4% evalue=1.E-100); Pseudomonas aeruginosa PA1885 conserved hypothetical protein (42.2% evalue=2.E-25) YP_068822.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_068823.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_068824.1 Modulates Rho-dependent transcription termination YP_068825.1 binds directly to 23S ribosomal RNA YP_068826.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_068827.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_068828.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_068829.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_068830.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_068831.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_068832.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_068833.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_068834.1 catalyzes the adenylation of ThiS which is involved in the formation of 5-methyl-4-(beta-hydroxyethyl)thiazole phosphate YP_068835.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_068836.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_068837.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_068838.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_068839.1 similar to Yersinia pestis YPO3735 hypothetical protein (100% evalue=1.E-139) YP_068840.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_068841.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_068842.1 similar to Yersinia pestis YPO3732 conserved hypothetical protein (99.4% evalue=1.E-109); Salmonella typhi STY3716 yjaG; conserved hypothetical protein (80.6% evalue=4.E-91) YP_068843.1 histone-like DNA-binding protein YP_068844.1 similar to Yersinia pestis YPO3730 yjaH; exported protein (99.5% evalue=1.E-121); Salmonella typhimurium STM4171 yjaH; inner membrane protein (42.5% evalue=5.E-43) YP_068845.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_068846.1 involved in de novo purine biosynthesis YP_068847.1 similar to Yersinia pestis YPCD1.93 transposase (100% evalue=2.E-44); Ralstonia solanacearum RS00015 tISRso12a, RSc2707; ISRSO12-transposase orfA protein (79.3% evalue=2.E-34) YP_068848.1 similar to Yersinia pestis YPCD1.94 transposase (99.2% evalue=1.E-146) YP_068849.1 similar to Yersinia pestis YPO3592 insertion sequence IS100, ATP-binding protein (100% evalue=1.E-142) YP_068850.1 similar to Yersinia pestis YPO3591 transposase for insertion sequence IS100 (100% evalue=0) YP_068851.1 similar to Bacillus subtilis BG11786 ytaP; hypothetical protein (28.9% evalue=5.E-26) YP_068852.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_068853.1 similar to Yersinia pestis YPO0252 membrane protein (100% evalue=3.E-53); Salmonella typhimurium STM4274 yjcH; inner membrane protein (66.6% evalue=2.E-35) YP_068854.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_068855.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system YP_068856.1 similar to Yersinia pestis YPO0255 two-component response regulator (98% evalue=1.E-113); Salmonella typhimurium STM1391 ssrB; Secretion system regulator: transcriptonal activator, homologous with degU/uvrY/bvgA (54.6% evalue=3.E-57) YP_068857.1 similar to Yersinia pestis YPO0256 two-component sensor/regulator (98.8% evalue=0); Salmonella typhi STY1728 ssrA, spiR; two-component sensor kinase (44.1% evalue=0) YP_068858.1 similar to Yersinia pestis YPO0257 possible type III secretion protein (99.8% evalue=0); Salmonella typhimurium STM1394 ssaC; Secretion system apparatus (51.5% evalue=1.E-138) YP_068859.1 similar to Yersinia pestis YPO0258 type-III secretion protein (99.7% evalue=0); Salmonella typhi STY1725 ssaD; pathogenicity island protein (31% evalue=4.E-52) YP_068860.1 similar to Yersinia pestis YP0259 type III secretion apparatus YP_068861.1 similar to Yersinia pestis YPO0260 AraC-family regulatory protein (99.5% evalue=1.E-115) YP_068862.1 similar to Yersinia pestis YPO0260a type III secretion apparatus (95.7% evalue=6.E-32) YP_068863.1 similar to Yersinia pestis YPO0261 type III secretion apparatus (100% evalue=5.E-39) YP_068864.1 similar to Yersinia pestis YPO0262 type III secretion apparatus (100% evalue=2.E-40) YP_068865.1 similar to Yersinia pestis YPO0263 type III secretion system apparatus lipoprotein (99.5% evalue=1.E-133); Salmonella typhi STY1711 ssaJ; pathogenicity island lipoprotein (45.3% evalue=9.E-56) YP_068866.1 similar to Yersinia pestis YPO0264 conserved hypothetical protein (100% evalue=1.E-110); Salmonella typhi STY1710 pathogenicity island protein (34.7% evalue=2.E-18) YP_068867.1 similar to Yersinia pestis YPO0265 type III secretion system apparatus protein (97.2% evalue=1.E-114); Salmonella typhimurium STM1411 ssaK; Secretion system apparatus (27.4% evalue=2.E-14) YP_068868.1 with SsaC forms part of a protein export system across the inner and outer cell membranes; part of the Salmonella pathogenicity island 2; part of the type III secretion system YP_068869.1 similar to Yersinia pestis YPO0267 type III secretion system ATP synthase (100% evalue=0); Salmonella typhi STY1705 ssaN; type III secretion ATP synthase (59.4% evalue=1.E-133) YP_068870.1 similar to Yersinia pestis YPO0268 type III secretion system apparatus protein (99.2% evalue=1.E-70); M. musculus 108655 Foxp1, 4932443N09Rik; forkhead box P1 (28.6% evalue=1.E-08) YP_068871.1 similar to Yersinia pestis YPO0268a hypothetical protein (98.5% evalue=3.E-35) YP_068872.1 similar to Yersinia pestis YPO0269 type III secretion system apparatus protein (98% evalue=1.E-176); Salmonella typhimurium STM1418 ssaQ; Secretion system apparatus (26.4% evalue=2.E-25) YP_068873.2 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_068874.1 similar to Yersinia pestis YPO0271 type III secretion apparatus protein (100% evalue=4.E-48); Salmonella typhimurium STM1420 ssaS; Secretion system apparatus: homology with YscS of the secretion system of Yersinia (60.7% evalue=1.E-22) YP_068875.1 similar to Yersinia pestis YPO0272 type III secretion apparatus protein (100% evalue=1.E-145); Salmonella typhi STY1699 ssaT; type III secretion protein (51.7% evalue=2.E-66) YP_068876.1 member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli YP_068877.1 similar to Yersinia pestis YPO0274 integral membrane protein (100% evalue=0); Escherichia coli b1929 yedE; hypothetical 44.4 kD protein in amyA-fliE intergenic region (ORF 48) (78.3% evalue=0) YP_068878.1 similar to Yersinia pestis YPO0275 conserved hypothetical protein (98.8% evalue=3.E-47); Escherichia coli b1930 yedF; hypothetical 8.6 kD protein in amyA-fliE intergenic region (ORF 9) (93.2% evalue=3.E-36) YP_068879.1 similar to Yersinia pestis YPO0276 LysR-family transcriptional regulator (100% evalue=0); Ralstonia solanacearum RS01682 probable transcription regulator protein (31% evalue=2.E-42) YP_068880.1 similar to Yersinia pestis YPO0277 transmembrane transport protein (100% evalue=0); Escherichia coli b3539 yhjV; hypothetical 47.3 kD protein in dctA-dppF intergenic region (O423) (62.6% evalue=1.E-157) YP_068881.1 similar to Yersinia pestis YPO0278 metC; cystathionine beta-lyase (100% evalue=0); Saccharomyces cerevisiae YFR055W cystathionine beta-lyase (64.1% evalue=1.E-131) YP_068882.1 with HmuTU is involved in the transport of hemin YP_068883.1 similar to Yersinia pestis YPO0280 hmuU; hemin transport system permease HmuU (100% evalue=0); Escherichia coli Z4918 chuU; permease of iron compound ABC transport system (66.5% evalue=1.E-115) YP_068884.1 similar to Yersinia pestis YPO0281 hmuT; hemin-binding periplasmic protein (99.2% evalue=1.E-150); Agrobacterium tumefaciens AGR_C_4467 hemin-binding periplasmic protein HmuT precursor (41.7% evalue=6.E-44) YP_068885.1 similar to Yersinia pestis YPO0282 hmuS; hemin transport protein (100% evalue=0); Escherichia coli ECs4379 hypothetical protein (67% evalue=1.E-130) YP_068886.1 similar to Yersinia pestis YPO0283 hmuR; hemin receptor precursor (99.4% evalue=0); Escherichia coli ECs4380 heme utilization/transport protein (67.8% evalue=0) YP_068888.1 similar to Yersinia pestis YPO0284 conserved hypothetical protein (99.5% evalue=1.E-120); Escherichia coli ECs4385 ShuY-like protein (55.4% evalue=2.E-55) YP_068889.1 similar to Yersinia pestis YPO0285 conserved hypothetical protein (98.3% evalue=5.E-99); Escherichia coli ECs4384 ShuX-like protein (59.3% evalue=1.E-53) YP_068890.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_068891.1 similar to Yersinia pestis YPO0287 methylenetetrahydrofolate reductase (99.6% evalue=1.E-153); Pseudomonas aeruginosa PA0430 metF; 5,10-methylenetetrahydrofolate reductase (25.2% evalue=1.E-21) YP_068892.1 similar to Yersinia pestis YPO0288 exported protein (100% evalue=9.E-85); Escherichia coli Z1603 terW_2; unknown associated with tellurite resistance (51.6% evalue=7.E-34) YP_068893.1 similar to Yersinia pestis YPO0289 ATP/GTP-binding protein (100% evalue=1.E-173); Escherichia coli Z1605 hypothetical protein (66.7% evalue=1.E-111) YP_068894.1 similar to Yersinia pestis YPO0290 conserved hypothetical protein (100% evalue=0); Escherichia coli Z1606 hypothetical protein (70.5% evalue=1.E-144) YP_068895.1 similar to Yersinia pestis YPO0291 conserved hypothetical protein (100% evalue=1.E-160); Escherichia coli Z1607 hypothetical protein (65.4% evalue=1.E-102) YP_068896.1 similar to Yersinia pestis YPO0292 conserved hypothetical protein (100% evalue=0); Escherichia coli Z1608 hypothetical protein (68.2% evalue=1.E-145) YP_068897.1 similar to Yersinia pestis YPO0293 conserved hypothetical protein (99.7% evalue=0); Escherichia coli ECs1350 hypothetical protein (55.1% evalue=1.E-106) YP_068898.1 similar to Yersinia pestis YPO0294 terZ; tellurium resistance protein (99.4% evalue=1.E-109); Escherichia coli ECs1351 tellurium resistance protein TerZ (76.6% evalue=2.E-82) YP_068899.1 similar to Yersinia pestis YPO0295 terA; tellurite resistance protein (99.7% evalue=0); Escherichia coli Z1172 terA; phage inhibition, colicin resistance and tellurite resistance protein (69.2% evalue=1.E-155) YP_068900.1 similar to Yersinia pestis YPO0296 terB; tellurite resistance protein (100% evalue=2.E-80); Escherichia coli ECs1353 tellurium resistance protein TerB (71.5% evalue=6.E-57) YP_068901.1 similar to Yersinia pestis YPO0297 terC; tellurium resistance protein (99.4% evalue=0); Escherichia coli Z1613 terC_2; phage inhibition, colicin resistance and tellurite resistance protein (83.9% evalue=1.E-164) YP_068902.1 similar to Yersinia pestis YPO0298 terD; tellurium resistance protein (100% evalue=1.E-106); Escherichia coli Z1614 terD_2; phage inhibition, colicin resistance and tellurite resistance protein (86.4% evalue=5.E-94) YP_068903.1 similar to Yersinia pestis YPO0299 terE; tellurium resistance protein (100% evalue=1.E-105); Escherichia coli Z1615 terE_2; phage inhibition, colicin resistance and tellurite resistance protein (85.3% evalue=4.E-91) YP_068904.1 similar to Yersinia pestis YPO0301 exported protein (100% evalue=1.E-115); Salmonella typhimurium STM4574 outer membrane protein (23.8% evalue=8.E-09) YP_068905.1 similar to Yersinia pestis YPO0302 outer membrane fimbrial usher protein (99.6% evalue=0); Escherichia coli b3216 yhcD; hypothetical outer membrane usher protein in gltF-nanT intergenic region precursor (27.2% evalue=8.E-80) YP_068906.1 member of the periplasmic pilus chaperone family of proteins YP_068907.1 similar to Yersinia pestis YPO0306 hypothetical protein (99.7% evalue=0) YP_068908.1 similar to Salmonella typhimurium STM4155 inner membrane protein (32.5% evalue=2.E-07) YP_068909.1 similar to Yersinia pestis YPO0308 oxidoreductase (99.7% evalue=0); Ralstonia solanacearum RS01873 conserved hypothetical protein (42.8% evalue=1.E-102) YP_068910.1 similar to Yersinia pestis YPO1672 conserved hypothetical protein (79.7% evalue=0) YP_068911.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_068912.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_068913.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_068914.1 similar to Yersinia pestis YPO0313 dgkA; diacylglycerol kinase (100% evalue=9.E-63); Escherichia coli ECs5025 diacylglycerol kinase (68.3% evalue=1.E-42) YP_068915.1 Represses a number of genes involved in the response to DNA damage YP_068916.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_068917.1 similar to Yersinia pestis YPO0316 conserved hypothetical protein (99.7% evalue=0); Salmonella typhi STY4439 yjbN; conserved hypothetical protein (77.7% evalue=1.E-149) YP_068918.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_068919.1 similar to Yersinia pestis YPO0319 qor, hcz; quinone oxidoreductase (99.6% evalue=0); Salmonella typhi STY4441 qor; quinone oxidoreductase (73.7% evalue=1.E-136) YP_068920.1 unwinds double stranded DNA YP_068921.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_068922.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_068923.1 similar to Yersinia pestis YPO0323 conserved hypothetical protein (100% evalue=3.E-66); Escherichia coli JW4018 yjbR; Hypothetical protein (57.5% evalue=5.E-35) YP_068924.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_068925.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_068926.1 similar to Yersinia pestis YPO0326 conserved hypothetical protein (100% evalue=3.E-58); Salmonella typhimurium STM4043 yiiL; cytoplasmic protein (77.8% evalue=1.E-45) YP_068927.1 similar to Yersinia pestis YPO0327 probable alcohol dehydrogenase (99.4% evalue=0); Salmonella typhi STY3830 alcohol dehydrogenase (79.8% evalue=1.E-175) YP_068928.1 similar to Yersinia pestis YPO0328 rhaD; rhamnulose-1-phosphate aldolase (99.6% evalue=1.E-158); Escherichia coli b3902 rhaD; rhamnulose-1-phosphate aldolase (68% evalue=1.E-109) YP_068929.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_068930.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_068931.1 activates the expression of the rhaBAD operon and rhaT gene YP_068932.1 activates the expression of rhaRS in response to L-rhamnose YP_068933.1 transports L-rhamnose and L-lyxose into the cell YP_068934.1 similar to Yersinia pestis YPO0335 hypothetical protein (91.6% evalue=6.E-41) YP_068935.1 similar to Yersinia pestis YPO0337 exported protein (100% evalue=9.E-81); Salmonella typhi STY1891 pertussis-like toxin subunit (46% evalue=2.E-27) YP_068936.1 similar to Yersinia pestis YPO0338 hypothetical protein. 98% identical YP_068937.1 similar to Yersinia pestis YPO3828 hypothetical protein (30% evalue=6.E-15) YP_068938.1 similar to Yersinia pestis YPO0341 TetR-family regulatory protein (99.4% evalue=1.E-105); Escherichia coli ECs5116 hypothetical protein (64.9% evalue=2.E-67) YP_068939.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_068940.1 similar to Yersinia pestis YPO0343 hydN; 4Fe-4S ferrodoxin (100% evalue=1.E-107); Salmonella typhimurium STM2843 hydN; electron transport protein (FeS senter) from formate to hydrogen (50.7% evalue=8.E-51) YP_068941.1 similar to Yersinia pestis YPO0344 fdhF; formate dehydrogenase H (99.4% evalue=0); Escherichia coli b4079 fdhF; formate dehydrogenase , formate-hydrogen-lyase-linked, selenocysteine-containing polypeptide (formate dehydrogenase-H alpha subunit) (62.9% evalue=0) YP_068942.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_068943.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_068944.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_068945.1 catalyzes the formation of fumarate from aspartate YP_068946.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_068947.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_068948.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_068949.1 similar to Yersinia pestis YPO0352 lipoprotein (99.2% evalue=2.E-66); Escherichia coli ECs5125 hypothetical protein (61.9% evalue=3.E-38) YP_068950.1 similar to Yersinia pestis YPO0353 conserved hypothetical protein (100% evalue=0); Salmonella typhimurium STM4333 yjeK; aminomutase (73.3% evalue=1.E-145) YP_068951.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_068952.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations YP_068953.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_068954.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_068955.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_068956.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_068957.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_068958.1 similar to Yersinia pestis YPO0363 membrane transport protein (99.5% evalue=0); Salmonella typhimurium STM4347 yjeP; periplasmic binding protein (70.1% evalue=0) YP_068959.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_068960.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_068961.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_068962.1 similar to Yersinia pestis YPO0367 iron-sulfur cluster-binding protein (100% evalue=0); Escherichia coli Z5773 yjeS; orf, hypothetical protein (74.6% evalue=0) YP_068963.1 similar to Yersinia pestis YPO0368 conserved hypothetical protein (99.8% evalue=0); Escherichia coli b4167 yjeF; hypothetical 54.7 kD protein in PSD-amiB intergenic region (URF1) (60.7% evalue=0) YP_068964.1 possibly involved in cell wall synthesis YP_068965.1 similar to Yersinia pestis YPO0370 N-acetylmuramoyl-L-alanine amidase-family protein (99.4% evalue=0); Escherichia coli ECs5145 N-acetylmuramoyl-l-alanine amidase II (62.8% evalue=1.E-145) YP_068966.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_068967.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_068968.1 Stimulates the elongation of poly(A) tails YP_068969.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_068970.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_068971.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_068972.1 similar to Yersinia pestis YPO0377 membrane protein (100% evalue=6.E-32); Escherichia coli JW4134 yjeT; Hypothetical protein (81.5% evalue=8.E-24) YP_068973.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_068974.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_068975.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_068976.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_068977.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_068978.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_068979.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_068980.1 similar to Yersinia pestis YPO3540 hypothetical protein. 98% identical. YP_068981.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_068982.1 binds single-stranded DNA at the primosome assembly site YP_068983.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_068984.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_068985.1 similar to Yersinia pestis YPO3534 exported protein (100% evalue=4.E-86) YP_068986.1 similar to Yersinia pestis YPO3533 conserved hypothetical protein (100% evalue=1.E-141); Salmonella typhimurium STM4396 ytfB; cell envelope opacity-associated protein A (45.1% evalue=2.E-36) YP_068987.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_068988.1 Involved in anaerobic NO protection and iron metabolism YP_068989.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_068990.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_068991.1 similar to Yersinia pestis YPO3528 exported protein (100% evalue=1.E-102); Salmonella typhi STY4763 ytfJ; exported protein (60.9% evalue=4.E-62) YP_068992.1 similar to Yersinia pestis YPO3527 conserved hypothetical protein (100% evalue=5.E-34); Escherichia coli JW4176 ytfK; Hypothetical protein (77.2% evalue=3.E-24) YP_068993.1 similar to Yersinia pestis YPO3526 membrane protein (100% evalue=0); Salmonella typhi STY4766 ytfL; membrane protein (81.3% evalue=0) YP_068994.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_068995.1 similar to Yersinia pestis YPO3524 exported protein (99.6% evalue=0); Salmonella typhimurium STM4409 ytfM; outer membrane protein (71.1% evalue=0) YP_068996.1 similar to Yersinia pestis YPO3523 exported protein (99.1% evalue=0); Salmonella typhi STY4769 ytfN; exported protein (56.8% evalue=0) YP_068997.1 similar to Yersinia pestis YPO3522 conserved hypothetical protein (100% evalue=9.E-68); Escherichia coli JW4181 ytfP; Hypothetical protein (61.2% evalue=9.E-39) YP_068998.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_068999.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_069000.1 similar to Yersinia pestis YPO3519 mpl; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (100% evalue=0); Escherichia coli Z5843 yjfG; UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (84.4% evalue=0) YP_069001.1 similar to Yersinia pestis YPO3518 exported protein (100% evalue=7.E-43); Escherichia coli b3238 yhcN; hypothetical 11.2 kD protein in argR-cafA intergenic region (54% evalue=3.E-21) YP_069002.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_069003.1 oxidizes malate to oxaloacetate YP_069004.1 similar to Yersinia pestis YPO2785 sfsB, nlp, sfs7; DNA-binding protein (73.9% evalue=2.E-26); Salmonella typhimurium STM2749 cytoplasmic protein (65% evalue=3.E-26) YP_069005.1 similar to Yersinia pestis YPO3514 conserved hypothetical protein (100% evalue=2.E-61); Salmonella typhimurium STM2373 cytoplasmic protein (33.6% evalue=6.E-08) YP_069006.1 similar to Yersinia pestis YPO3513 ispB, cel; octaprenyl-diphosphate synthase (99.6% evalue=1.E-179); Salmonella typhimurium STM3305 ispB; octaprenyl diphosphate synthase (80.6% evalue=1.E-142) YP_069007.1 similar to Yersinia pestis YPO3512 rplU; 50S ribosomal protein L21 (100% evalue=5.E-54); Salmonella typhimurium STM3304 rplU; 50S ribosomal subunit protein L21 (89.3% evalue=9.E-50) YP_069008.1 involved in the peptidyltransferase reaction during translation YP_069009.1 similar to Yersinia pestis YPO3510 membrane protein (100% evalue=0); Salmonella typhi STY3481 membrane protein (80.5% evalue=1.E-135) YP_069010.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_069011.1 similar to Yersinia pestis YPO3508 basS, pmrB; two-component system sensor protein (99.7% evalue=0); Salmonella typhimurium STM4291 basS; sensory kinase in two-component regulatory system with BasR (50.7% evalue=6.E-92) YP_069012.1 response regulator in two-component regulatory system with BasS YP_069013.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_069014.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_069015.1 similar to Yersinia pestis YPO3504 conserved hypothetical protein (100% evalue=2.E-48); Salmonella typhimurium STM3298 yhbY; RNA-binding protein containing KH domain (83.5% evalue=7.E-40) YP_069016.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_069017.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_069018.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_069019.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_069020.1 similar to Yersinia pestis YPO3499 secG; protein-export membrane protein (100% evalue=1.E-56); Salmonella typhi STY3471 secG; protein-export membrane protein (78.3% evalue=7.E-44) YP_069021.2 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_069022.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_069023.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_069024.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_069025.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_069026.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_069027.1 similar to Yersinia pestis YPO3490 pnp; polyribonucleotide nucleotidyltransferase (99.8% evalue=0); Escherichia coli Z4525 pnp; polynucleotide phosphorylase; cytidylate kinase activity (87.4% evalue=0) YP_069028.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_069029.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_069030.1 similar to Yersinia pestis YPO3487 hypothetical protein. 100% identical YP_069031.1 similar to Yersinia pestis YPO3486 conserved hypothetical protein. 100% identical. YP_069032.1 similar to Yersinia pestis YPO3485 transcriptional regulatory protein (100% evalue=5.E-51) YP_069033.1 similar to Yersinia pestis YPO3484 conserved hypothetical protein (99.4% evalue=0); Escherichia coli JW3129 yhbW; Hypothetical protein (o335) (70.6% evalue=1.E-135) YP_069034.1 similar to Yersinia pestis YPO3483 multidrug efflux protein (100% evalue=0); Escherichia coli Z2509 efflux pump (65.1% evalue=1.E-117) YP_069035.1 similar to Yersinia pestis YPO3482 multidrug efflux protein (99.8% evalue=0); Escherichia coli Z2508 efflux pump (71.3% evalue=0) YP_069036.1 similar to Yersinia pestis YPO3481 ibeB; probable outer membrane efflux lipoprotein (99.5% evalue=0); Escherichia coli ECs1865 outer membrane channel protein (52.7% evalue=1.E-127) YP_069037.1 similar to Yersinia pestis YPO3480 conserved hypothetical protein (100% evalue=1.E-170); Escherichia coli Z4520 yhbV; orf, hypothetical protein (75.8% evalue=1.E-132) YP_069038.1 similar to Yersinia pestis YPO3479 protease (99.3% evalue=0); Salmonella typhimurium STM3274 yhbU; protease (88.8% evalue=1.E-171) YP_069039.1 similar to Yersinia pestis YPO3477 lipid carrier protein (99.4% evalue=2.E-92); Salmonella typhimurium STM3273 yhbT; lipid carrier protein (73.1% evalue=1.E-61) YP_069040.1 similar to Yersinia pestis YPO3476 acetyltransferase (98.8% evalue=2.E-89); Escherichia coli ECs4037 hypothetical protein (69.4% evalue=7.E-61) YP_069041.1 similar to Yersinia pestis YPO3475 conserved hypothetical protein (98.9% evalue=2.E-47); Salmonella typhimurium STM3271 yhbQ; cytoplasmic protein (70.8% evalue=2.E-27) YP_069042.1 similar to Yersinia pestis YPO3474 hypothetical protein (99.1% evalue=0) YP_069043.1 similar to Yersinia pestis YPO3473 exported protein (99.7% evalue=0) YP_069044.1 similar to Yersinia pestis YPO3472 sugar binding protein (99.7% evalue=0); Agrobacterium tumefaciens Atu3338 thuE; ABC transporter, substrate binding protein [trehalose/maltose] (25.9% evalue=3.E-20) YP_069045.1 similar to Yersinia pestis YPO3471 sugar transport system, permease (99.3% evalue=1.E-168); Agrobacterium tumefaciens AGR_pAT_78 probable binding protein dependent transport protein (36% evalue=4.E-46) YP_069046.1 similar to Yersinia pestis YPO3470 sugar transport system, permease (100% evalue=1.E-158); Synechocystis slr1723 lacG; lactose transport system permease (36.2% evalue=5.E-42) YP_069047.1 similar to Yersinia pestis YPO3469 sugar ABC transporter, ATP-binding protein (100% evalue=0); Mesorhizobium loti mlr8490 ABC transporter, ATP-binding protein (55.4% evalue=1.E-107) YP_069048.1 similar to Yersinia pestis YPO3473 exported protein (42.1% evalue=4.E-76) YP_069049.1 similar to Yersinia pestis YPO3467 conserved hypothetical protein (98.6% evalue=4.E-81); Salmonella typhimurium STM3270 yhbP; cytoplasmic protein (48.9% evalue=2.E-35) YP_069050.1 similar to Yersinia pestis YPO3466 conserved hypothetical protein (100% evalue=1.E-117); Salmonella typhimurium STM3268 yraR; nucleoside-diphosphate-sugar epimerase (56% evalue=2.E-59) YP_069051.1 required for the use of phosphonates and phosphite as phosphorus sources YP_069052.1 similar to Yersinia pestis YPO3464 phnN; PhnN protein (100% evalue=1.E-110); Escherichia coli Z5697 phnN; ATP-binding component of phosphonate transport (56.4% evalue=2.E-49) YP_069053.1 similar to Yersinia pestis YPO3463 phnM; PhnM protein (99.2% evalue=0); Escherichia coli Z5698 phnM; phosphonate metabolism (74% evalue=1.E-163) YP_069054.1 similar to Yersinia pestis YPO3462 phnL; phosphonates transport ATP-binding protein (99.5% evalue=1.E-134); Escherichia coli b4096 phnL; phosphonates transport ATP-binding protein phnL (76% evalue=4.E-92) YP_069055.1 similar to Yersinia pestis YPO3461 phnK; phosphonates transport ATP-binding protein (99.6% evalue=1.E-146); Escherichia coli Z5700 phnK; ATP-binding component of phosphonate transport (85% evalue=1.E-119) YP_069056.1 similar to Yersinia pestis YPO3460 phnJ; PhnJ protein (99.6% evalue=1.E-171); Escherichia coli ECs5081 phosphonate metabolism (85.6% evalue=1.E-142) YP_069057.1 similar to Yersinia pestis YPO3459 phnI; PhnI protein (98.7% evalue=0); Escherichia coli b4099 phnI; phnI protein (75.2% evalue=1.E-149) YP_069058.1 similar to Yersinia pestis YPO3458 phnH; PhnH protein (99.5% evalue=1.E-118); Escherichia coli ECs5083 phosphonate metabolism (47.3% evalue=4.E-46) YP_069059.1 similar to Yersinia pestis YPO3457 phnG; PhnG protein (100% evalue=1.E-86); Escherichia coli b4101 phnG; phnG protein (50% evalue=3.E-35) YP_069060.1 may be involved in phosphonate uptake and biodegradation YP_069061.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_069062.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_069063.1 similar to Yersinia pestis YPO3453 ABC transporter, ATP-binding protein (99.5% evalue=1.E-127); Agrobacterium tumefaciens AGR_L_526 dipeptide transport system ATP-binding protein (50.6% evalue=1.E-57) YP_069064.1 similar to Yersinia pestis YPO3452 ABC transporter transporter, ATP-binding protein (100% evalue=1.E-166); Mesorhizobium loti mlr5516 oligopeptide ABC transporter, ATP-binding protein (43.6% evalue=5.E-59) YP_069065.1 similar to Yersinia pestis YPO3451 transporter, permease (100% evalue=1.E-158); Sinorhizobium meliloti SMc01527 dppC2; dipeptide transport system permease ABC transporter protein (59% evalue=2.E-87) YP_069066.1 similar to Yersinia pestis YPO3450 transporter, permease (100% evalue=0); Sinorhizobium meliloti SMc01526 dppB2; dipeptide transport system permease ABC transporter protein (48.5% evalue=1.E-86) YP_069067.1 similar to Sinorhizobium meliloti SMc01525 dppA2; dipeptide binding periplasmic protein (40% evalue=1.E-104); Mesorhizobium loti mlr5513 ABC transporter, periplasmic oligopeptide-binding protein (41% evalue=1.E-106) YP_069068.1 similar to Yersinia pestis YPO3447 conserved hypothetical protein (100% evalue=2.E-84); Escherichia coli Z5864 yjgK; orf, hypothetical protein (71.1% evalue=3.E-58) YP_069069.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_069070.1 similar to Yersinia pestis YPO3445 conserved hypothetical protein (100% evalue=9.E-79); Escherichia coli ECs5232 hypothetical protein (76.2% evalue=7.E-58) YP_069071.1 similar to Yersinia pestis YPO3444 acetyltransferase (99.4% evalue=1.E-91); Salmonella typhimurium STM4473 yjgM; acetyltransferase (71% evalue=6.E-61) YP_069072.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_069073.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_069074.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_069075.1 similar to Yersinia pestis YPO3440 membrane protein (99.7% evalue=0); Salmonella typhimurium STM4479 yjgP; permease (72.7% evalue=1.E-148) YP_069076.1 similar to Yersinia pestis YPO3439 membrane protein (100% evalue=0); Escherichia coli Z5874 yjgQ; orf, hypothetical protein (76.6% evalue=1.E-159) YP_069077.1 similar to Ureaplasma urealyticum UU095 hsdR; type I restriction enzyme R protein (26.8% evalue=2.E-71); Listeria innocua lin0521 similar to HsdR type IC restriction subunit (30.9% evalue=1.E-97) YP_069078.1 similar to Streptococcus pyogenes SPy1905 hsdS; type I restriction enzyme, S subunit (26% evalue=8.E-30); Staphylococcus aureus_N315 SA0392 hsdS; type I restriction enzyme, S subunit (25.1% evalue=2.E-18) YP_069079.1 similar to Streptococcus pyogenes SPy1906 hsdM; type I restriction enzyme M protein (43% evalue=1.E-101); Lactococcus lactis L0309 hsdM; type I restriction enzyme M protein (40.2% evalue=1.E-101) YP_069080.1 similar to Yersinia pestis YPO0398 M48 peptidase family protein (99.7% evalue=0); Sinorhizobium meliloti SMc00783 hypothetical transmembrane protein (26.4% evalue=2.E-25) YP_069081.1 similar to Yersinia pestis YPO0399 membrane protein (98.7% evalue=0); Salmonella typhimurium STM4474 yjgN; inner membrane protein (30.2% evalue=1.E-43) YP_069082.1 similar to Yersinia pestis YPO0400 hypothetical protein (100% evalue=1.E-102) YP_069083.1 similar to Yersinia pestis YPO0401 transcriptional regulator (99.6% evalue=1.E-166); Salmonella typhimurium STM4117 yijO; paral regulator (AraC/XylS family) (54.9% evalue=2.E-86) YP_069084.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog YP_069085.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS YP_069086.2 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site YP_069087.1 similar to Yersinia pestis YPO0405 phosphotransferase system, enzyme I / PTS system, fructose-specific IIA component (97.1% evalue=0); Salmonella typhimurium STM4110 ptsA (63.7% evalue=0) YP_069088.1 similar to Yersinia pestis YPO0406 exported protein (100% evalue=8.E-86); Escherichia coli ECs5320 glycoprotein/receptor (46.2% evalue=3.E-32) YP_069089.1 similar to Yersinia pestis YPO0407 conserved hypothetical protein (100% evalue=5.E-51); Salmonella typhi STY3791 conserved hypothetical protein (79.1% evalue=4.E-40) YP_069090.1 similar to Yersinia pestis YPO0408 aldolase (99.6% evalue=1.E-163); Salmonella typhimurium STM4078 yneB; fructose-1,6-bisphosphate aldolase (85.5% evalue=1.E-142) YP_069091.1 similar to Yersinia pestis YPO0409 periplasmic solute-binding protein (99.7% evalue=0); Escherichia coli ECs2123 LACI-type transcriptional regulator (84.4% evalue=1.E-163) YP_069092.1 similar to Yersinia pestis YPO0410 ABC transporter permease (99.6% evalue=0); Salmonella typhimurium STM4076 ydeZ; ABC superfamily (membrane), sugar transport protein (79.5% evalue=1.E-149) YP_069093.1 similar to Yersinia pestis YPO0411 ABC transporter permease (98.8% evalue=0); Escherichia coli b1514 ydeY; simple sugar transport system permease (75.7% evalue=1.E-148) YP_069094.1 similar to Yersinia pestis YPO0412 ABC transporter ATP-binding protein (98.6% evalue=0); Salmonella typhimurium STM4074 ego; ABC-type sugar, aldose transport system, ATPase component (67.4% evalue=0) YP_069095.1 similar to Salmonella typhi STY3797 ydeW; regulatory protein (69.6% evalue=1.E-120); Salmonella typhimurium STM4073 ydeW; transcriptional repressor (69.2% evalue=1.E-120) YP_069096.1 similar to Yersinia pestis YPO0415 carbohydrate kinase (99.8% evalue=0); Salmonella typhi STY3798 ydeV; sugar kinase (80.9% evalue=0) YP_069097.1 similar to Yersinia pestis YPO0416 lipopolysaccharide core biosynthesis protein (99.4% evalue=0); Escherichia coli ECs4507 lipopolysaccharide core biosynthesis protein RfaQ (41.5% evalue=5.E-63) YP_069098.1 similar to Yersinia pestis YPO0417 O-antigen biosynthesis protein (100% evalue=0); H. influenzae HI0874 hypothetical protein HI0874 (25.1% evalue=2.E-08) YP_069099.1 similar to Salmonella typhimurium STM1373 sufS; selenocysteine lyase (48.6% evalue=1.E-108); M. leprae ML0842 conserved hypothetical protein (48.6% evalue=1.E-110) YP_069100.1 similar to Thermoplasma volcanium TVG1333406 isovaleryl-CoA dehydrogenase precursor (24.7% evalue=5.E-23); A. fulgidus AF2244 acd-11; acyl-CoA dehydrogenase (27.2% evalue=2.E-25) YP_069101.1 . This gene has not been found in the Yersinia pestis CO92 genome YP_069102.1 . This gene has not been found in the Yersinia pestis CO92 genome YP_069103.1 similar to Mycobacterium tuberculosis_CDC1551MT3301 HesA/MoeB/ThiF family protein (42.6% evalue=4.E-74); Anabaena all2906 moeB; molybdopterin biosynthesis protein (45% evalue=3.E-76) YP_069104.1 similar to Bacillus halodurans transposase related protein (weak) ref|NP_243386.1|, evalue=0.092, 33% identity in 56 aa. This gene has not been found in the Yersinia pestis CO92 genome YP_069105.1 similar to Yersinia pestis YPO0418 membrane protein. 95% identical YP_069106.1 similar to Yersinia pestis YPO0419 exported protein (98.7% evalue=2.E-36) YP_069107.1 similar to Yersinia pestis YPO0420 lipoprotein (99.7% evalue=0); Vibrio cholerae VC1674 periplasmic linker protein, (28.1% evalue=7.E-40) YP_069108.1 similar to Yersinia pestis YPO0421 multi-drug efflux protein (99.9% evalue=0); Vibrio cholerae VC1673 transporter, AcrB/D/F family (50.8% evalue=0) YP_069109.1 similar to Yersinia pestis YPO0422 hypothetical protein (100% evalue=4.E-58) YP_069110.1 similar to Yersinia pestis YPO0423 hypothetical protein (98.8% evalue=4.E-43) YP_069111.1 similar to Yersinia pestis YPO0424 pectinesterase (100% evalue=0); A. thalianan At5g49180 K21P3.5; pectin methylesterase (32.6% evalue=1.E-27) YP_069112.1 similar to Yersinia pestis YPO0425 hmsT; HmsT protein (98.9% evalue=0); Salmonella typhimurium STM4551 diguanylate cyclase/phosphodiesterase domain 1 (44.2% evalue=3.E-80) YP_069113.1 similar to Yersinia pestis YPO0426 membrane protein (98.7% evalue=2.E-38); Salmonella typhimurium STM4552 inner membrane protein (46.5% evalue=6.E-15) YP_069114.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_069115.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_069116.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_069117.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_069118.1 similar to Yersinia pestis YPO0431 osmY; osmotically inducible protein Y (99% evalue=1.E-103); Salmonella typhi STY4911 osmY; periplasmic protein (63.5% evalue=3.E-66) YP_069119.1 similar to Yersinia pestis YPO0432 exported protein (98.1% evalue=3.E-22); Escherichia coli Z5978 hypothetical protein (90.3% evalue=7.E-20) YP_069120.1 similar to Yersinia pestis YPO0433 conserved hypothetical protein (99.7% evalue=0); Escherichia coli JW4340 yjjU; Hypothetical protein (65.6% evalue=1.E-128) YP_069121.1 similar to Yersinia pestis YPO0434 metalloenzyme (99.6% evalue=1.E-147); Escherichia coli JW4341 yjjV; Hypothetical protein (63.9% evalue=2.E-89) YP_069122.1 similar to Yersinia pestis YPO0435 Na+ dependent nucleoside transporter-family protein (99.5% evalue=0); Vibrio cholerae VC2352 NupC family protein (72.2% evalue=1.E-169) YP_069123.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_069124.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_069125.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_069126.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_069127.1 similar to Yersinia pestis YPO0441 smp; membrane protein (100% evalue=1.E-125); Salmonella typhi STY4924 smp; membrane protein (65.4% evalue=2.E-75) YP_069128.1 catalyzes the formation of serine from O-phosphoserine YP_069129.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_069130.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_069131.1 similar to Yersinia pestis YPO0445 conserved hypothetical protein (99.2% evalue=0); Pseudomonas aeruginosa PA0574 hypothetical protein (56.3% evalue=1.E-116) YP_069132.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_069133.1 similar to Yersinia pestis YPO0448 lipoprotein (98.7% evalue=2.E-88); Pseudomonas aeruginosa PA1119 probable outer membrane lipoprotein (52.4% evalue=5.E-37) YP_069134.1 similar to Yersinia pestis YPO0449 exported protein (100% evalue=0); Pseudomonas aeruginosa PA1120 conserved hypothetical protein (55.6% evalue=1.E-117) YP_069135.1 similar to Yersinia pestis YPO0450 membrane protein (100% evalue=1.E-117); Pseudomonas aeruginosa PA1121 conserved hypothetical protein (43.2% evalue=2.E-33) YP_069136.1 similar to Yersinia pestis YPO0451 cation-transporting P-type ATPase (99.8% evalue=0); Pseudomonas aeruginosa PA1429 probable cation-transporting P-type ATPase (44.2% evalue=0) YP_069137.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_069138.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_069139.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_069140.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_069141.1 similar to Yersinia pestis YPO0456 rob; right origin-binding protein (100% evalue=1.E-170); Salmonella typhimurium STM4586 rob; transcriptional regulator (AraC/XylS family) (67.4% evalue=1.E-112) YP_069142.1 similar to Yersinia pestis YPO0457 creA; exported protein (100% evalue=2.E-84); Salmonella typhi STY4934 creA; conserved hypothetical protein (79.7% evalue=7.E-67) YP_069143.1 similar to Yersinia pestis YPO0458 arcA, dye, fexA, sfrA, seg, msp, cpxC; aerobic respiration control protein (100% evalue=1.E-135); Escherichia coli Z6004 arcA; negative response regulator of genes in aerobic pathways, (sensors, ArcB and CpxA) (92.8% evalue=1.E-125) YP_069144.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_069145.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_069146.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_069147.1 similar to Yersinia pestis YPO0462 conserved hypothetical protein (100% evalue=1.E-144); Escherichia coli JW0005 yaaA; inner membrane transport protein (78.5% evalue=1.E-113) YP_069148.1 Maintains the balance of metabolites in the pentose-phosphate pathway YP_069149.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_069150.1 similar to Yersinia pestis YPO0465 transport protein (99.3% evalue=0); Pseudomonas aeruginosa PA5370 probable MFS transporter (68.9% evalue=1.E-165) YP_069151.1 similar to Yersinia pestis YPO2884 exported protein (34% evalue=1.E-128) YP_069152.1 similar to Yersinia pestis YPO0467 yaaH; membrane protein (98.5% evalue=1.E-111); Salmonella typhimurium STM0009 yaaH; regulator (76.3% evalue=2.E-79) YP_069153.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_069154.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_069155.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_069156.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_069157.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_069158.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_069159.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_069160.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_069161.1 similar to Yersinia pestis YPO0476a fkpB, slpA; FKBP-type peptidyl-prolyl cis-trans isomerase (99.3% evalue=3.E-82); Salmonella typhi STY0057 fkpB; probable FkbB-type 16 kD peptidyl-prolyl cis-trans isomerase (69.4% evalue=3.E-54) YP_069162.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_069163.1 similar to Yersinia pestis YPO3280 tnp; transposase for the IS1541 insertion element (100% evalue=6.E-89) YP_069164.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_069165.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_069166.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_069167.1 similar to Yersinia pestis YPO0483 LysE type translocator (96.5% evalue=1.E-109); Pseudomonas aeruginosa PA2710 hypothetical protein (73.8% evalue=3.E-81) YP_069168.1 similar to Yersinia pestis YPO0484 yjjP; membrane protein (99.6% evalue=1.E-148); Salmonella typhi STY4899 membrane protein (74% evalue=1.E-107) YP_069169.2 similar to Yersinia pestis YPO0485 membrane protein (97.4% evalue=8.E-79); Salmonella typhimurium STM4545 inner membrane protein (75.9% evalue=3.E-63) YP_069170.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_069171.1 similar to Yersinia pestis YPO488 with a frameshift. Either this gene or the Yersinia pestis gene are a possible pseudogene. YP_069172.1 similar to Yersinia pestis YPO0489 exported protein (96.1% evalue=3.E-84) YP_069173.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_069174.1 protein associated with Co2+ and Mg2+ efflux YP_069175.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_069176.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_069177.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_069178.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_069179.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_069180.1 similar to Yersinia pestis YPO0497 rluA; ribosomal large subunit pseudouridine synthase A (100% evalue=1.E-118); Escherichia coli b0058 rluA; ribosomal large subunit pseudouridine synthase A. (pseudouridylate synthase) (uracil hydrolyase) (77.1% evalue=2.E-90) YP_069181.1 similar to Yersinia pestis YPO0498 hypothetical protein (100% evalue=1.E-144) YP_069182.1 similar to Yersinia pestis YPO0499 hypothetical protein (100% evalue=0); Pseudomonas aeruginosa PA0082 hypothetical protein (33.8% evalue=1.E-07) YP_069183.1 similar to Yersinia pestis YPO0500 conserved hypothetical protein (100% evalue=1.E-101); Pseudomonas aeruginosa PA0083 conserved hypothetical protein (59.8% evalue=9.E-50) YP_069184.1 similar to Yersinia pestis YPO0501 conserved hypothetical protein (99.8% evalue=0); Pseudomonas aeruginosa PA0084 conserved hypothetical protein (63.8% evalue=0) YP_069185.1 similar to Yersinia pestis YPO0502 conserved hypothetical protein (100% evalue=8.E-98); Pseudomonas aeruginosa PA0085 conserved hypothetical protein (38.9% evalue=2.E-27) YP_069186.1 similar to Yersinia pestis YPO0503 conserved hypothetical protein (100% evalue=4.E-80); Salmonella typhimurium STM0269 cytoplasmic protein (33% evalue=4.E-10) YP_069187.1 similar to Yersinia pestis YPO0504 conserved hypothetical protein (99.8% evalue=0); Pseudomonas aeruginosa PA0088 hypothetical protein (29.4% evalue=3.E-57) YP_069188.1 similar to Yersinia pestis YPO0505 conserved hypothetical protein (100% evalue=0); Pseudomonas aeruginosa PA0089 hypothetical protein (27.9% evalue=9.E-25) YP_069189.1 similar to Yersinia pestis YPO0506 clpB, htpM; Clp ATPase (100% evalue=0); Pseudomonas aeruginosa PA0090 probable ClpA/B-type chaperone (44.4% evalue=0) YP_069190.1 similar to Yersinia pestis YPO0507 conserved hypothetical protein (99.8% evalue=0); Pseudomonas aeruginosa PA0095 conserved hypothetical protein (36.1% evalue=6.E-96) YP_069191.1 similar to Yersinia pestis YPO0509 hypothetical protein (99.6% evalue=0) YP_069192.1 similar to Yersinia pestis YPO0510 hypothetical protein (100% evalue=0); Anabaena alr1142 hypothetical protein (33.8% evalue=8.E-10) YP_069193.1 similar to Yersinia pestis YPO0511 hypothetical protein (100% evalue=1.E-112) YP_069194.1 similar to Yersinia pestis YPO0511a hypothetical protein (100% evalue=6.E-67) YP_069195.1 similar to Yersinia pestis YPO0512 lipoprotein (99.3% evalue=1.E-88) YP_069196.1 similar to Yersinia pestis YPO0513 conserved hypothetical protein (100% evalue=0); Pseudomonas aeruginosa PA0079 hypothetical protein (34.6% evalue=2.E-72) YP_069197.1 similar to Yersinia pestis YPO0514 OmpA-family membrane protein (99.8% evalue=0); Salmonella typhi STY0305 membrane protein (29.3% evalue=3.E-26) YP_069198.1 similar to Yersinia pestis YPO0515 membrane protein (99.8% evalue=0); Pseudomonas aeruginosa PA0077 hypothetical protein (25.2% evalue=3.E-93) YP_069199.1 similar to Yersinia pestis YPO0516 hypothetical protein (100% evalue=1.E-61) YP_069200.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_069201.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_069202.1 similar to Yersinia pestis YPO0519 DedA-family membrane protein (100% evalue=1.E-148); Escherichia coli Z0074 yabI; orf, hypothetical protein (58.8% evalue=3.E-84) YP_069203.2 with TbpA and ThiP is part of the thiamine and TPP transport system YP_069204.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_069205.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_069206.1 . This gene has not been found in the Yersinia pestis CO92 genome YP_069207.1 similar to Yersinia pestis YPCD1.89 YPCD1.89 (65.4% evalue=6.E-35); Salmonella typhimurium STM2764 integrase core domain (84.4% evalue=1.E-51) YP_069208.1 activates sgrS under glucose-phosphate stress conditions YP_069209.1 similar to Escherichia coli b0070 yabM; sugar efflux transporter A (70.6% evalue=1.E-154); Escherichia coli JW0069 yabM, leuD; Sugar efflux protein (70.9% evalue=1.E-154) YP_069210.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_069211.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_069212.2 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_069213.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_069214.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_069215.1 similar to Yersinia pestis YPO0537 AMP-binding enzyme-family protein (100% evalue=0); Vibrio cholerae VC2484 long-chain-fatty-acid--CoA ligase, (56.3% evalue=0) YP_069216.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_069217.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_069218.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_069219.1 similar to Yersinia pestis YPO0544 membrane protein (100% evalue=1.E-79); Salmonella typhimurium STM2800 inner membrane protein (65.5% evalue=2.E-49) YP_069220.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_069221.1 similar to Yersinia pestis YPO0547 conserved hypothetical protein (100% evalue=0); Escherichia coli JW0080 yabC; Hypothetical protein (ORFB) (77.1% evalue=1.E-136) YP_069222.1 membrane bound cell division protein at septum containing leucine zipper motif YP_069223.1 similar to Yersinia pestis YPO0549 ftsI, pbpB; penicillin-binding protein 3 (99.8% evalue=0); Escherichia coli ECs0088 septum formation protein FtsI (84.7% evalue=0) YP_069224.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_069225.1 deleted EC_number 6.3.2.15; similar to Yersinia pestis YPO0551 murF, mra; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diamino pimelate--D-alanyl-D-alanyl ligase (99.7% evalue=0); Escherichia coli b0086 murF, mra (69.6% evalue=1.E-175) YP_069226.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_069227.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_069228.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_069229.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_069230.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_069231.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_069232.1 involved in septum formation YP_069233.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_069234.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_069235.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_069236.1 similar to Yersinia pestis YPO0562 conserved hypothetical protein (100% evalue=1.E-92); Vibrio cholerae VC2395 hypothetical protein (34.1% evalue=1.E-14) YP_069237.2 secM translational pause allows for the initiation of secA translation YP_069238.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_069239.1 similar to Yersinia pestis YPO0565 mutT; mutator protein MutT (100% evalue=1.E-69); Salmonella typhimurium STM0137 mutT; 7,8-dihydro-8-oxoguanine-triphosphatase, prefers dGTP (65% evalue=6.E-40) YP_069240.1 similar to Yersinia pestis YPO3968 tnp; transposase for the IS1541 insertion element (100% evalue=1.E-88) YP_069241.1 similar to Yersinia pestis YPO3432 conserved hypothetical protein (100% evalue=2.E-37); Escherichia coli ECs0105 hypothetical protein (80.3% evalue=4.E-25) YP_069242.1 similar to Yersinia pestis YPO3431 conserved hypothetical protein (100% evalue=1.E-140); Salmonella typhi STY0161 yacF; conserved hypothetical protein (69.9% evalue=2.E-95) YP_069243.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_069244.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_069245.1 similar to Yersinia pestis YPO1583 transposase for the IS285 insertion element (100% evalue=0) YP_069246.1 similar to Yersinia pestis YPO3427 hofC, hopC; type II secretion system protein (99.4% evalue=0); Salmonella typhimurium STM0142 hofC; component in type IV pilin biogenesis (38.4% evalue=8.E-77) YP_069247.1 similar to Yersinia pestis YPO3426 hofB, hopB; type II secretion system protein (99.8% evalue=0); Escherichia coli Z0117 hofB; integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake (45.3% evalue=1.E-112) YP_069248.1 similar to Yersinia pestis YPO3425 ppdD; prepilin peptidase dependent protein D precursor (100% evalue=9.E-83); Escherichia coli Z0118 ppdD; prelipin peptidase dependent protein (57.4% evalue=4.E-42) YP_069249.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_069250.1 similar to Yersinia pestis YPO3423 ampD; signalling protein in beta-lactamase regulation (100% evalue=1.E-105); Escherichia coli b0110 ampD; ampD protein (65% evalue=1.E-68) YP_069251.1 involved in regulation of beta-lactamase; signaling protein YP_069252.1 similar to Yersinia pestis YPO3421 aroP; aromatic amino acid transport protein (99.7% evalue=0) YP_069253.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_069254.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_069255.1 similar to Yersinia pestis YPO3418 aceF; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (96.7% evalue=0); Escherichia coli JW0111 aceF; Dihydrolipoamide S-acetyltransferase (81.1% evalue=0) YP_069256.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_069257.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_069258.1 similar to Yersinia pestis YPO3414 conserved hypothetical protein (100% evalue=6.E-67); Salmonella typhi STY0182 conserved hypothetical protein (69.7% evalue=1.E-47) YP_069259.1 similar to Yersinia pestis YPO3413 yddG; membrane protein (97.3% evalue=1.E-168); Escherichia coli ECs2077 hypothetical protein (42.1% evalue=2.E-63) YP_069260.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_069261.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_069262.1 similar to Yersinia pestis YPO3410 yacC; exported protein (100% evalue=3.E-61); Escherichia coli ECs0126 hypothetical protein (71.1% evalue=2.E-40) YP_069263.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_069264.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively YP_069265.1 similar to Yersinia pestis YPO3407 yadF; carbonic anhydrase (100% evalue=1.E-127); Escherichia coli b0126 yadF; carbonic anhydrase (73.1% evalue=3.E-93) YP_069266.1 similar to Yersinia pestis YPO3406 yadG; ABC transporter, ATP-binding protein (99.6% evalue=1.E-171); Salmonella typhimurium STM0172 yadG; ABC-type multidrug transport system, ATPase component (82.4% evalue=1.E-142) YP_069267.1 similar to Yersinia pestis YPO3405 yadH; ABC transporter, integral membrane protein (100% evalue=1.E-144); Salmonella typhimurium STM0173 yadH; ABC superfamily (membrane) transport protein (80% evalue=1.E-118) YP_069268.1 similar to Yersinia pestis YPO3404 conserved hypothetical protein (99.7% evalue=0); Salmonella typhimurium STM0179 yadE; xylanase/chitin deacetylase (65.7% evalue=1.E-150) YP_069269.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_069270.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_069271.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_069272.1 similar to Yersinia pestis YPO3400 folK; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (100% evalue=4.E-88); Salmonella typhimurium STM0183 folK; 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, PPPK (70.9% evalue=1.E-55) YP_069273.2 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_069274.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_069275.1 similar to Yersinia pestis YPO3397 dksA; DnaK suppressor protein homologue (100% evalue=1.E-82); Salmonella typhi STY0211 dksA; dosage-dependent dnaK suppressor protein (96% evalue=2.E-79) YP_069276.1 Regulatory factor involved in maltose metabolism YP_069277.1 similar to Yersinia pestis YPO3395 ligT; 2'-5' RNA ligase (99.4% evalue=1.E-108); Escherichia coli JW0143 ligT; 2'-5' RNA ligase (58.1% evalue=5.E-56) YP_069278.2 similar in sequence to the ATP-dependent RNA helicase HrpA YP_069279.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_069280.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_069281.2 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_069282.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_069283.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_069284.2 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_069285.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_069286.1 similar to Yersinia pestis YPO3386 yadS; membrane protein (100% evalue=1.E-112); Salmonella typhimurium STM0205 yadS; inner membrane protein (87.1% evalue=1.E-98) YP_069287.1 solute binding component of the vitamin B12 transport system BtuCDF YP_069288.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_069289.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_069290.1 protease Do; required at high temperature; degrades damaged proteins YP_069291.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_069292.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_069293.1 similar to Yersinia pestis YPO3379 hypothetical protein. YP_069294.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era YP_069295.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_069296.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_069297.1 similar to Yersinia pestis YPO3375 sodC; superoxide dismutase [Cu-Zn] precursor (94% evalue=1.E-105); Salmonella typhimurium STM1044 sodC; Gifsy-2 prophage: superoxide dismutase precursor (Cu-Zn) (72.2% evalue=3.E-71) YP_069298.1 similar to Yersinia pestis YPO3374 conserved hypothetical protein (100% evalue=1.E-128); Salmonella typhi STY3080 conserved hypothetical protein (79.8% evalue=1.E-105) YP_069299.1 similar to Yersinia pestis YPO3373 ygcM; 6-pyruvoyl tetrahydrobiopterin synthase family protein (100% evalue=1.E-68); Escherichia coli JW2735 ptpS; 6-pyruvoyl tetrahydrobiopterin synthase (PTPS) (83.1% evalue=3.E-59) YP_069300.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_069301.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_069302.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_069303.1 similar to Yersinia pestis YPO3369 conserved hypothetical protein (100% evalue=7.E-75) YP_069304.1 similar to Yersinia pestis conserved hypothetical protein emb|CAC90635.1| (AJ414150) (122 aa), evalue=2e-05, 39.6% identity in 63 aa, and to Rhizobium meliloti (Sinorhizobium meliloti) hypothetical protein SMC04441 swall|Q92K60| (62 aa), evalue=2e-05, 35. YP_069305.1 similar to Yersinia pestis YPO3367 cysG; siroheme synthase (99.5% evalue=0); Neisseria meningitidis NMB1194 uroporphyrin-III C-methyltransferase / precorrin-2 oxidase / ferrochelatase (60% evalue=1.E-153) YP_069306.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_069307.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_069308.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_069309.1 similar to Yersinia pestis YPO3363 ygbE; membrane protein (100% evalue=5.E-58); Salmonella typhimurium STM2932 ygbE; inner membrane protein (53.9% evalue=4.E-24) YP_069310.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_069311.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_069312.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_069313.1 catalyzes the modification of U13 in tRNA(Glu) YP_069314.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_069315.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_069316.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_069317.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_069318.1 similar to Yersinia pestis YPO1583 transposase for the IS285 insertion element (100% evalue=0) YP_069319.1 This protein performs the mismatch recognition step during the DNA repair process YP_069320.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_069321.1 similar to Yersinia pestis YPO3352 ydjJ; Zinc-binding dehydrogenase (100% evalue=0) YP_069322.1 similar to Yersinia pestis YPO3351 dehydrogenase (100% evalue=1.E-144); Listeria innocua lin0362 similar to dehydrogenase/reductase (54.7% evalue=5.E-78) YP_069323.1 similar to Yersinia pestis YPO3350 dhaK, ycgT; dihydroxyacetone kinase (100% evalue=0); Sinorhizobium meliloti SMb20314 dihydroxyacetone kinase (63.3% evalue=1.E-115) YP_069324.1 similar to Yersinia pestis YPO3349 conserved hypothetical protein (99.5% evalue=1.E-122); Sinorhizobium meliloti SMb20313 dihydroxyacetone kinase (57.2% evalue=4.E-59) YP_069325.1 similar to Yersinia pestis YPO3348 transcriptional regulatory protein (100% evalue=1.E-179); Pasteurella multocida PM1646 SmoC-like regulatory protein (68.4% evalue=1.E-124) YP_069326.1 similar to Yersinia pestis YPO3347 arsB, arsF; arsenical pump membrane protein (99.7% evalue=0); Escherichia coli Z4904 arsB; arsenical pump membrane protein (83.9% evalue=0) YP_069327.1 regulates the expression of of the arsRBC involved in resistance to arsenic YP_069328.1 similar to Yersinia pestis YPO3345 hypothetical protein (98.9% evalue=3.E-48) YP_069329.1 similar to Yersinia pestis YPO3344 hypothetical protein. 100% identical YP_069330.1 similar to Yersinia pestis YPO3343 probable extracellular solute-binding protein (99.2% evalue=1.E-142); Pseudomonas aeruginosa PA3475 pheC; cyclohexadienyl dehydratase precursor (prephenate dehydratase / arogenate dehydratase) (38% evalue=1.E-36) YP_069331.1 similar to Yersinia pestis YPO3342 yhjA; cytochrome C peroxidase (99.5% evalue=0); Escherichia coli b3518 yhjA; probable cytochrome C peroxidase (56.1% evalue=1.E-140) YP_069333.1 similar to Escherichia coli ECs1360 Iha adhesin (56.2% evalue=0); Escherichia coli Z1617 receptor (56.2% evalue=0) YP_069334.1 similar to Yersinia pestis YPO3339 hypothetical protein (100% evalue=0) YP_069335.1 similar to Yersinia pestis YPO3337 map; methionine aminopeptidase (100% evalue=1.E-150); Xylella fastidiosa XF0111 methionine aminopeptidase (62.6% evalue=1.E-91) YP_069336.1 similar to Yersinia pestis YPO3336 conserved hypothetical protein (100% evalue=2.E-41) YP_069337.1 similar to Yersinia pestis YPO3335 fumA, fumB; fumarate hydratase, class I (100% evalue=0); Escherichia coli JW1604 fumA; fumarate hydratase, class I (86.4% evalue=0) YP_069338.1 similar to Yersinia pestis YPO3334 sgbK, lyx, lyxK, xylK; L-xylulose kinase (99.5% evalue=0); Escherichia coli JW3552 lyxK; Cryptic L-xylulose kinase (L-xylulokinase) (42.8% evalue=1.E-114) YP_069339.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_069340.1 similar to Yersinia pestis YPO3332 sugar ABC transporter, permease (100% evalue=0); Sinorhizobium meliloti SMb20487 sugar ABC transporter permease (49.1% evalue=1.E-75) YP_069341.1 similar to Yersinia pestis YPO3331 sugar ABC transporter, permease (100% evalue=1.E-180); Escherichia coli Z0418 permease component of transport system, probably ribose specific (44.6% evalue=2.E-72) YP_069342.1 similar to Yersinia pestis YPO3634 ABC transporter ATP binding protein (54.3% evalue=1.E-147) YP_069343.1 similar to Yersinia pestis YPO3328 sugar ABC transporter, periplasmic protein (99.4% evalue=0); Agrobacterium tumefaciens AGR_L_271 periplasmic binding protein, probable substrate ribose (60.5% evalue=2.E-98) YP_069344.1 similar to Yersinia pestis YPO3327 fucR; deoR-family regulatory protein (99.2% evalue=1.E-150); B. halodurans BH1553 transcriptional regulator (DeoR family) (35.9% evalue=1.E-42) YP_069345.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_069346.1 similar to Yersinia pestis YPO3325 dmsA; anaerobic dimethyl sulfoxide reductase chain A (99.8% evalue=0); Salmonella typhimurium STM0964 dmsA; anaerobic dimethyl sulfoxide reductase, subunit A (80.3% evalue=0) YP_069347.1 similar to Yersinia pestis YPO3324 dmsB; anaerobic dimethyl sulfoxide reductase chain B (99.5% evalue=1.E-126); Salmonella typhimurium STM0965 dmsB; anaerobic dimethyl sulfoxide reductase, subunit B (85.8% evalue=1.E-112) YP_069348.1 similar to Yersinia pestis YPO3323 dmsC; anaerobic dimethyl sulfoxide reductase chain C (99.6% evalue=1.E-160); Salmonella typhimurium STM0966 dmsC; anaerobic dimethyl sulfoxide reductase, subunit C (67% evalue=1.E-106) YP_069349.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane YP_069350.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm YP_069351.1 similar to Yersinia pestis YPO3320 cybC; cytochrome B562 (98.4% evalue=5.E-66); Salmonella typhi STY4778 cybC; soluble cytochrome b562 (52.3% evalue=1.E-29) YP_069352.1 similar to Yersinia pestis YPO3319 katY; catalase-peroxidase (100% evalue=0); Sinorhizobium meliloti SMa2379 catalase/peroxidase (61.1% evalue=0) YP_069353.1 similar to Yersinia pestis YPO3318 sugar ABC transporter, periplasmic protein (99.6% evalue=1.E-173); Sinorhizobium meliloti SMb20349 probable ABC transporter sugar-binding protein (72.1% evalue=1.E-118) YP_069354.1 similar to Yersinia pestis YPO3317 lipoprotein (100% evalue=1.E-111); Mesorhizobium loti mll7013 hypothetical protein (34.1% evalue=8.E-16) YP_069355.1 similar to Yersinia pestis YPO3316 sugar ABC transporter, ATP-binding protein (99.6% evalue=0); Mesorhizobium loti mll7012 ribose ABC transporter, ATP-binding protein (54.2% evalue=1.E-144) YP_069356.1 similar to Yersinia pestis YPO3315 rbsC; sugar ABC transporter, permease (98.1% evalue=0); Sinorhizobium meliloti SMb20352 probable sugar ABC transporter permease (59.8% evalue=1.E-120) YP_069357.1 similar to Yersinia pestis YPO3314 N-terminal region of transketolase (100% evalue=1.E-159); Listeria monocytogenes lmo1032 transketolase (45.1% evalue=2.E-61) YP_069358.1 similar to Yersinia pestis YPO3313 C-terminal region of transketolase (100% evalue=1.E-177); Listeria monocytogenes lmo1033 similar to transketolase (40.5% evalue=3.E-56) YP_069359.1 similar to Yersinia pestis YPO3312 glycerol kinase (99.7% evalue=0); Agrobacterium tumefaciens Atu1903 glpK; glycerol kinase (44.3% evalue=1.E-108) YP_069360.1 similar to Yersinia pestis YPO3311 conserved hypothetical protein (99.3% evalue=0); Thermotoga maritima TM0951 hypothetical protein (51.5% evalue=1.E-134) YP_069361.1 similar to Yersinia pestis YPO3310 transcriptional regulatory protein (100% evalue=1.E-173); Agrobacterium tumefaciens AGR_C_3494 transcriptional regulator (40.5% evalue=2.E-63) YP_069362.1 similar to Yersinia pestis YPO3309 membrane protein (99.5% evalue=0); Pseudomonas aeruginosa PA3355 hypothetical protein (56% evalue=1.E-132) YP_069363.1 similar to Yersinia pestis YPO3308 competence-damaged protein (100% evalue=3.E-88); Escherichia coli JW2670 ygaD; Hypothetical protein (66.6% evalue=3.E-55) YP_069364.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_069365.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_069366.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_069367.1 affects carbohydrate metabolism; has regulatory role in many processes YP_069368.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_069369.1 similar to Yersinia pestis YPO3302 yqaA; membrane protein (99.2% evalue=7.E-76); Salmonella typhimurium STM2819 yqaA; inner membrane protein (58.1% evalue=7.E-46) YP_069370.1 involved in the first step of glutathione biosynthesis YP_069371.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_069372.2 similar to Yersinia pestis YPO3298 yfjD; membrane protein (99.2% evalue=0); Escherichia coli JW2593 yfjD; Hypothetical protein (77.3% evalue=0) YP_069373.1 similar to Yersinia pestis YPO3297 corE; membrane protein (99.6% evalue=1.E-166); Escherichia coli ECs3474 hypothetical protein (74.8% evalue=1.E-114) YP_069374.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_069375.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_069376.1 Essential for efficient processing of 16S rRNA YP_069377.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_069378.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_069379.1 similar to Yersinia pestis YPO3290 ydiY; exported protein (100% evalue=1.E-145); Escherichia coli ECs2428 hypothetical protein (54% evalue=6.E-77) YP_069380.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_069381.1 unknown function; when overproduced it confers drug-resistance YP_069382.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_069383.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_069384.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_069385.1 similar to Yersinia pestis YPO3279 yfiA; sigma 54 modulation protein (100% evalue=9.E-63); Escherichia coli Z3890 yfiA; yhbH sigma 54 modulator (79.6% evalue=6.E-46) YP_069386.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_069387.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_069388.1 similar to Yersinia pestis YPO3276 conserved hypothetical protein (99.5% evalue=1.E-138); Escherichia coli ECs3456 hypothetical protein (62.1% evalue=2.E-85) YP_069389.1 similar to Yersinia pestis YPO3275 clpB, htpM; Clp ATPase (99.8% evalue=0); Escherichia coli JW2573 clpB; ClpB protein (heat shock protein f84.1) (86.6% evalue=0) YP_069390.1 similar to Yersinia pestis YPO3274 lipoprotein (100% evalue=2.E-63); Salmonella typhimurium STM2653 yfiM; outer membrane lipoprotein (55.7% evalue=7.E-31) YP_069391.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_069392.1 similar to Yersinia pestis YPO3272 yfiQ; acetyltransferase (99.6% evalue=0); Escherichia coli Z3869 yfiQ; orf, hypothetical protein (75.6% evalue=0) YP_069393.1 similar to Yersinia pestis YPO3271 conserved hypothetical protein (98.7% evalue=1.E-143); Escherichia coli b2583 yfiP; hypothetical 27.0 kD protein in ung-pssA intergenic region (60.8% evalue=3.E-75) YP_069394.1 similar to Yersinia pestis YPO3270 trxC; thioredoxin 2 (97.9% evalue=3.E-81); Escherichia coli Z3867 trxC; thioredoxin-like protein (76.9% evalue=4.E-63) YP_069395.1 similar to Yersinia pestis YPO3269 yfiF; tRNA/rRNA methyltransferase (99.2% evalue=0); Salmonella typhimurium STM2648 yfiF; tRNA/rRNA methyltransferase (60% evalue=1.E-123) YP_069396.1 similar to Yersinia pestis YPO3268 emrB; multidrug resistance protein B (99.8% evalue=0); Escherichia coli JW2661 emrB; Multidrug resistant protein EmrB (84% evalue=0) YP_069397.1 similar to Yersinia pestis YPO3267 emrA; multidrug resistance protein A (100% evalue=0); Salmonella typhi STY2940 emrA; multidrug resistance protein A (71.4% evalue=1.E-157) YP_069398.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_069399.1 similar to Yersinia pestis YPO3265 membrane protein (99.1% evalue=2.E-59); Escherichia coli JW2658 ygaH; Hypothetical protein (55.2% evalue=3.E-28) YP_069400.1 similar to Yersinia pestis YPO3264 amino acid transporter (99.2% evalue=1.E-141); Escherichia coli Z3983 hypothetical protein (71.3% evalue=1.E-92) YP_069401.1 similar to Yersinia pestis YPO3263 probable sugar transporter (99.7% evalue=0); Salmonella typhi STY2938 transmembrane transport protein (75.3% evalue=1.E-162) YP_069402.1 similar to Yersinia pestis YPO3262 hypothetical protein (98.7% evalue=1.E-84); Caulobacter crescentus CC2614 hypothetical protein (47.9% evalue=8.E-26) YP_069403.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_069404.1 similar to Yersinia pestis YPO3260 hypothetical protein (100% evalue=5.E-31) YP_069405.1 similar to Yersinia pestis YPO3259 rpiR-family transcriptional regulatory protein (100% evalue=1.E-153); Sinorhizobium meliloti SMc04363 hypothetical protein (32.7% evalue=1.E-30) YP_069406.1 similar to Yersinia pestis YPO3258 membrane protein. 94% identical. YP_069407.1 similar to Yersinia pestis YPO3257 amino acid ABC transporter, periplasmic protein (99.6% evalue=1.E-145); Agrobacterium tumefaciens AGR_C_2566 antigenic protein (61.1% evalue=5.E-82) YP_069408.1 similar to Yersinia pestis YPO3256 amino acid ABC transporter, permease (100% evalue=1.E-119); Agrobacterium tumefaciens AGR_C_2567 amino acid ABC transporter, permease (55.2% evalue=2.E-59) YP_069409.1 similar to Yersinia pestis YPO3255 amino acid ABC transporter, permease (99.5% evalue=1.E-122); Agrobacterium tumefaciens Atu1390 ABC transporter, membrane spanning protein (60.9% evalue=1.E-67) YP_069410.1 similar to Yersinia pestis YPO3254 amino acid ABC transporter, ATP-binding protein (100% evalue=1.E-137); Ralstonia solanacearum RS01498 probable amino-acid ATP-binding ABC transporter protein (63.2% evalue=1.E-79) YP_069411.1 similar to Caulobacter crescentus CC2604 aminotransferase, class V (60.6% evalue=1.E-136); B. halodurans BH0762 transaminase (52.6% evalue=1.E-116) YP_069412.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_069413.1 similar to Salmonella typhi STY0353 possible hydrolase (67.4% evalue=1.E-100); Salmonella typhimurium STM0308 yafV; amidohydrolase (67.8% evalue=1.E-101) YP_069414.1 catalyzes the transfer of an amino moiety YP_069415.1 catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway YP_069416.1 similar to Xylella fastidiosa XF2211 enolase-phosphatase (48.5% evalue=2.E-50); Pseudomonas aeruginosa PA1685 masA; enolase-phosphatase E-1 (50.6% evalue=3.E-55) YP_069417.1 similar to Xylella fastidiosa XF2210 dioxygenase (52.2% evalue=5.E-51); Pseudomonas aeruginosa PA1684 probable oxidase (55.8% evalue=3.E-56) YP_069418.1 similar to Thermotoga maritima TM0911 translation initiation factor, eIF-2B alpha subunit-related (44.7% evalue=2.E-65); A. aeolicus aq_2114 eif; initiation factor eIF-2B alpha subunit (45.9% evalue=4.E-66) YP_069419.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_069420.1 similar to Yersinia pestis YPO3248 hxuB; surface-exposed protein (99.6% evalue=0); H. influenzae HI0263 hxuB; heme-hemopexin utilization protein B precursor (30.4% evalue=1.E-65) YP_069421.1 similar to Yersinia pestis YPO3247 hmwA; adhesin (95.6% evalue=0) YP_069422.1 similar to Yersinia pestis YPO3246 hmwC; accessory processing protein (99.3% evalue=0) YP_069423.1 similar to Yersinia pestis YPO3245 hypothetical protein (100% evalue=1.E-141) YP_069424.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_069425.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_069426.1 similar to Yersinia pestis YPO3242 conserved hypothetical protein (100% evalue=1.E-155); Escherichia coli b0223 yafJ; amidotransferase (86.2% evalue=1.E-134) YP_069427.1 similar to Yersinia pestis YPO3241 yafK; exported protein (99.1% evalue=1.E-141); Salmonella typhi STY0357 yafK; exported protein (60.7% evalue=7.E-82) YP_069428.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_069429.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_069430.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_069431.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_069432.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_069433.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_069434.1 similar to Yersinia pestis YPO3234 apbE; thiamine biosynthesis lipoprotein (99.7% evalue=0); Vibrio cholerae VC2289 thiamin biosynthesis lipoprotein ApbE (64.2% evalue=1.E-118) YP_069435.1 similar to Yersinia pestis YPO3233 exported protein (100% evalue=3.E-37); Vibrio cholerae VC2288 conserved hypothetical protein (58.8% evalue=1.E-19) YP_069436.1 similar to Yersinia pestis YPO3232 exported protein (99% evalue=1.E-177) YP_069437.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_069438.2 similar to Yersinia pestis YPO3230 pepD, pepH; aminoacyl-histidine dipeptidase (99.5% evalue=0); Escherichia coli JW0227 pepD; X-his dipeptidase precursor (78.3% evalue=0) YP_069439.1 similar to Yersinia pestis YPO3682 lysR-family transcriptional regulatory protein (38.2% evalue=1.E-12) YP_069440.1 similar to Yersinia pestis YPO3227 carbohydrate-binding protein (100% evalue=0); Vibrio cholerae VCA0140 spindolin-related protein (34.5% evalue=6.E-50) YP_069441.1 similar to Yersinia pestis YPO3226 membrane protein. YP_069442.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_069443.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_069444.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_069445.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_069446.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_069447.1 similar to Yersinia pestis YPO3220 conserved hypothetical protein (99.2% evalue=1.E-140); Salmonella typhimurium STM1798 ycgR; inner membrane protein (44.2% evalue=2.E-49) YP_069448.1 similar to Yersinia pestis YPO3219 membrane protein (100% evalue=6.E-42) YP_069449.1 similar to Yersinia pestis YPO3218 conserved hypothetical protein (98.2% evalue=6.E-94); Escherichia coli ECs0206 biotin synthesis protein (64% evalue=2.E-64) YP_069450.1 similar to Yersinia pestis YPO3217 hypothetical protein. 88% identical. YP_069451.1 similar to Yersinia pestis YPO3216 methyltransferase (99.4% evalue=1.E-102); B. halodurans BH2056 unknown conserved protein in others (28.8% evalue=3.E-15) YP_069452.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_069453.1 similar to Yersinia pestis YPO3213 conserved hypothetical protein (100% evalue=6.E-50); Salmonella typhi STY0424 yaiE; conserved hypothetical protein (65.9% evalue=1.E-31) YP_069454.1 Required for efficient pilin antigenic variation YP_069455.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_069456.1 similar to Salmonella typhimurium STM0395 sbcC; ATP-dependent dsDNA exonuclease (43.9% evalue=0); Pseudomonas aeruginosa PA4282 probable exonuclease (33.3% evalue=1.E-140) YP_069457.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_069458.1 similar to Yersinia pestis YPO3205 phoB; phosphate regulon transcriptional regulatory protein (100% evalue=1.E-129); Salmonella typhi STY0432 phoB; phosphate regulon transcriptional regulatory protein PhoB (90.3% evalue=1.E-119) YP_069459.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_069460.1 similar to Yersinia pestis YPO3203 pstS; phosphate binding protein (99.7% evalue=0); Pseudomonas aeruginosa PA5369 phosphate transport system substrate-binding protein (58.1% evalue=2.E-97) YP_069461.1 similar to Yersinia pestis YPO3202 brnQ; branched-chain amino acid transport system II carrier protein (100% evalue=0); Salmonella typhimurium STM0399 brnQ; LIVCS family, branched chain amino acid transporter system II (LIV-II) (75.9% evalue=0) YP_069462.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_069463.1 similar to Yersinia pestis YPO3200 malZ; maltodextrin glucosidase (99.8% evalue=0); Salmonella typhimurium STM0401 malZ; maltodextrin glucosidase (58.8% evalue=0) YP_069464.1 similar to Yersinia pestis YPO3199 probable short-chain dehydrogenase (100% evalue=1.E-126); Pseudomonas aeruginosa PA4079 probable dehydrogenase (38.9% evalue=2.E-39) YP_069465.1 similar to Ralstonia solanacearum RS03690 ggt1, RSp0274; probable gamma-glutamyltranspeptidase signal peptide protein (57.4% evalue=0); Mesorhizobium loti mlr5711 gamma-glutamyltranspeptidase (56.5% evalue=1.E-174) YP_069466.1 similar to Yersinia pestis YPO3194 ahpC; alkyl hydroperoxide reductase subunit c (100% evalue=1.E-114); Salmonella typhi STY0440 thiol - alkyl hydroperoxide reductase (86.5% evalue=1.E-100) YP_069467.1 similar to Yersinia pestis YPO3193 conserved hypothetical protein (100% evalue=1.E-111); Salmonella typhi STY0441 yajB; conserved hypothetical protein (61.6% evalue=3.E-66) YP_069468.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_069469.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_069470.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_069471.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_069472.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_069473.1 similar to Yersinia pestis YPO3186 hypothetical protein (100% evalue=1.E-110) YP_069474.1 similar to Yersinia pestis YPO3184 conserved hypothetical protein (100% evalue=9.E-80); Escherichia coli b0413 ybaD; hypothetical 17.2 kD protein in tsx-ribg intergenic region (ORF1) (86.5% evalue=8.E-71) YP_069475.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil YP_069476.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_069477.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_069478.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_069479.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_069480.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_069481.1 similar to Yersinia pestis YPO3176 ispA; geranyltranstransferase (99.6% evalue=1.E-170); Salmonella typhi STY0462 ispA; geranyltranstransferase (73.1% evalue=1.E-122) YP_069482.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_069483.1 similar to Yersinia pestis YPO3174 hypothetical protein. 100% identical YP_069484.1 Required for the synthesis of the thiazole moiety YP_069485.1 similar to Yersinia pestis YPO3172 thiJ; 4-methyl-5(B-hydroxyethyl)-thiazol monophosphate biosynthesis enzyme (100% evalue=1.E-107); Escherichia coli b0424 thiJ; 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme (73.9% evalue=5.E-78) YP_069486.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_069487.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_069488.1 similar to Yersinia pestis YPO3169 yajR; transporter (100% evalue=0); Salmonella typhi STY0475 hpothetical major facilitator family transport protein (75.2% evalue=0) YP_069489.1 converts protoheme IX and farnesyl diphosphate to heme O YP_069490.1 similar to Yersinia pestis YPO3167 cyoD; cytochrome O ubiquinol oxidase subunit CyoD (100% evalue=3.E-56); Escherichia coli b0429 cyoD; cytochrome o ubiquinol oxidase operon protein cyoD (65.1% evalue=1.E-35) YP_069491.1 similar to Yersinia pestis YPO3166 cyoC; cytochrome O ubiquinol oxidase subunit III (100% evalue=1.E-116); Salmonella typhimurium STM0441 cyoC; cytochrome o ubiquinol oxidase subunit III (76% evalue=2.E-89) YP_069492.1 similar to Yersinia pestis YPO3165 cyoB; cytochrome O ubiquinol oxidase subunit I (100% evalue=0); Salmonella typhimurium STM0442 cyoB; cytochrome o ubiquinol oxidase subunit I (84.1% evalue=0) YP_069493.1 similar to Yersinia pestis YPO3164 cyoA; cytochrome O ubiquinol oxidase subunit II (100% evalue=0); Escherichia coli b0432 cyoA; cytochrome o ubiquinol oxidase subunit II (66.8% evalue=1.E-118) YP_069494.1 similar to Yersinia pestis YPO3163 yfeN; exported protein (100% evalue=1.E-154); Salmonella typhimurium STM2423 yfeN; outer membrane protein (60.9% evalue=1.E-91) YP_069495.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_069496.1 similar to Yersinia pestis YPO3161 yajG; lipoprotein (100% evalue=1.E-102); Salmonella typhi STY0487 yajG; lipoprotein (73.4% evalue=3.E-77) YP_069497.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_069498.1 similar to Yersinia pestis YPO3159 hypothetical protein. 100% identical. YP_069499.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_069500.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_069501.1 binds and unfolds substrates as part of the ClpXP protease YP_069502.1 similar to Yersinia pestis YPO3155 lon, capR, deg, muc, lopA; ATP-dependent protease La (100% evalue=0); Salmonella typhi STY0492 lon; Lon protease (91% evalue=0) YP_069503.1 histone-like DNA-binding protein YP_069504.1 similar to Yersinia pestis YPO3153 ppiD; peptidyl-prolyl cis-trans isomerase D (99.8% evalue=0); Salmonella typhimurium STM0452 cypD; peptidyl prolyl isomerase (59.4% evalue=0) YP_069505.1 similar to Yersinia pestis YPO3152 ybaV; exported protein (100% evalue=1.E-78); Salmonella typhi STY0495 ybaV; exported protein (44.7% evalue=4.E-15) YP_069506.1 similar to Yersinia pestis YPO3151 conserved hypothetical protein (100% evalue=2.E-74); Salmonella typhi STY0496 conserved hypothetical protein (69.4% evalue=2.E-48) YP_069507.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_069508.1 similar to Yersinia pestis YPO3149 conserved hypothetical protein (99.2% evalue=0); Escherichia coli Z0552 ybaE; orf, hypothetical protein (46.1% evalue=1.E-151) YP_069509.1 similar to Yersinia pestis YPO3148 haloacid dehalogenase-like hydrolase (99.2% evalue=1.E-161); Escherichia coli ECs0500 hypothetical protein (57.3% evalue=1.E-86) YP_069510.1 similar to Yersinia pestis YPO3147 Pyridoxal-phosphate dependent protein (99.7% evalue=0); Salmonella typhimurium STM0458 cysteine synthase/cystathionine beta-synthase (76.8% evalue=1.E-154) YP_069511.1 similar to Yersinia pestis YPO3146 probable AsnC-family regulatory protein (100% evalue=3.E-84); Salmonella typhi STY0502 ybaO; hypothetical transcriptional regulator (76.8% evalue=4.E-63) YP_069512.1 similar to Yersinia pestis YPO3145 mdlA, mdl; probable ABC transporter (ATP-binding protein) (99.4% evalue=0); Escherichia coli JW0438 mdlA; Multidrag resistance-like ATP-binding protien (76.5% evalue=0) YP_069513.1 similar to Yersinia pestis YPO3144 mdlB, mdl; probable ATP transporter (ATP-binding protein) (99.1% evalue=0); Escherichia coli b0449 mdlB; multidrug resistance protein (78.7% evalue=0) YP_069514.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_069515.1 similar to Yersinia pestis YPO3142 amtB; probable ammonium transporter (100% evalue=0); Escherichia coli b0451 amtB; probable ammonium transporter (79% evalue=0) YP_069516.1 similar to Yersinia pestis YPO3141 tesB; acyl-CoA thioesterase II (100% evalue=1.E-166); Escherichia coli ECs0506 acyl-CoA thioesterase II (78.9% evalue=1.E-132) YP_069517.1 similar to Yersinia pestis YPO3140 ybaY; lipoprotein (99.4% evalue=7.E-91); Escherichia coli Z0565 ybaY; glycoprotein/polysaccharide metabolism (56.2% evalue=7.E-46) YP_069518.1 similar to Yersinia pestis YPO3139 6-O-methylguanine DNA methyltransferase family protein (97.4% evalue=3.E-83); Escherichia coli Z0566 ybaZ; orf, hypothetical protein (62.6% evalue=2.E-36) YP_069519.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_069520.1 similar to Yersinia pestis YPO3137 conserved hypothetical protein (100% evalue=2.E-68); Escherichia coli b0461 ybaJ; hypothetical 14.6 kD protein in hha-acrB intergenic region (65.7% evalue=2.E-40) YP_069521.1 similar to Yersinia pestis YPO3136 hypothetical protein (100% evalue=2.E-63) YP_069522.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_069523.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_069524.1 similar to Yersinia pestis YPO3133 acrB, acrE; multidrug efflux protein (99.8% evalue=0); Salmonella typhimurium STM0475 acrB; RND family, acridine efflux pump (84% evalue=0) YP_069525.1 similar to Yersinia pestis YPO3132 acrA, mtcA; multidrug efflux protein (100% evalue=0); Salmonella typhimurium STM0476 acrA; acridine efflux pump (73.9% evalue=1.E-162) YP_069526.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_069527.1 similar to Yersinia pestis YPO3130 conserved hypothetical protein (100% evalue=2.E-60); Salmonella typhimurium STM1769 ychN; ACR involved in intracellular sulfur reduction (81.1% evalue=3.E-49) YP_069528.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_069529.1 similar to Yersinia pestis YPO3128 conserved hypothetical protein (100% evalue=6.E-22); Salmonella typhimurium STM0480 ybaM; inner membrane protein (54.9% evalue=1.E-07) YP_069530.1 similar to Yersinia pestis YPO3127 priC; primosomal replication protein n'' (98.8% evalue=1.E-93); Salmonella typhimurium STM0481 priC; primosomal replication protein N (39.2% evalue=2.E-26) YP_069531.1 similar to Salmonella typhi STY0526 ybaN; membrane protein (69.6% evalue=6.E-49); Salmonella typhimurium STM0482 ybaN; phage gene 58 (69.6% evalue=6.E-49) YP_069532.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_069533.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_069534.1 similar to Yersinia pestis YPO3121 conserved hypothetical protein (100% evalue=4.E-57); Salmonella typhimurium STM0485 ybaB; cytoplasmic protein (91.8% evalue=3.E-52) YP_069535.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_069536.1 molecular chaperone YP_069537.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_069538.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_069539.1 catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose YP_069540.1 similar to Yersinia pestis YPO3115 ddhA, rfbF; glucose-1-phosphate cytidylyltransferase (99.6% evalue=1.E-155); Salmonella typhimurium STM2092 rfbF; glucose-1-phosphate cytidylyltransferase (80.5% evalue=1.E-126) YP_069541.1 similar to Salmonella typhi STY2301 rfbG; CDP-glucose 4,6-dehydratase (73.5% evalue=1.E-161); Salmonella typhimurium STM2091 rfbG; CDP-glucose 4,6-dehydratase (73.2% evalue=1.E-160) YP_069542.1 similar to Yersinia pestis YPO3113 ddhC; CDP-4-keto-6-deoxy-D-glucose-3-dehydratase (99.7% evalue=0); Salmonella typhi STY2300 rfbH; dehydratase RfbH (87.4% evalue=0) YP_069543.1 similar to Yersinia pestis YPO3112 prt, rfbS; paratose synthase (99.2% evalue=1.E-159); Salmonella typhi STY2299 rfbS; paratose synthase (43.9% evalue=2.E-64) YP_069544.1 similar to Yersinia pestis YPO3111 wbyH; exported protein (99% evalue=0); P. horikoshii PH0425 hypothetical protein (25.1% evalue=1.E-32) YP_069545.1 similar to Yersinia pestis YPO3110 wzx; O-unit flippase (90.3% evalue=0) YP_069546.1 similar to Methanocaldococcus jannaschii MJ1057 glycosyl transferase, (25.3% evalue=5.E-10); B. halodurans BH3713 glycosyltransferase (29.7% evalue=2.E-13) YP_069547.1 similar to Yersinia pestis YPO3107 wbyJ; mannosyltransferase (99.7% evalue=0); Clostridium acetobutylicum CAC3051 glycosyltransferase (26.6% evalue=2.E-08) YP_069549.1 similar to Yersinia pestis YPO3104 wbyK; mannosyltransferase (99.7% evalue=0); Synechocystis slr1064 rfbU, mtfA; mannosyltransferase B (36.3% evalue=2.E-41) YP_069550.1 similar to Escherichia coli JW2038 gmd; GDP-mannose 4,6-dehydratase (GDP-D-mannose dehydratase) (79.6% evalue=1.E-177); Escherichia coli Z3217 gmd; GDP-D-mannose dehydratase (79.6% evalue=1.E-177) YP_069551.1 similar to Escherichia coli b2052 fcl, wcaG; GDP-fucose synthetase (75.3% evalue=1.E-142); Escherichia coli JW2037 fcl; GDP-fucose synthetase (75.3% evalue=1.E-142) YP_069552.1 similar to Yersinia pestis YPO3099 manC, rfbM; mannose-1-phosphate guanylyltransferase (100% evalue=0); Salmonella typhimurium STM2105 manC; mannose-1-phosphate in colanic acid gene cluster (61.8% evalue=1.E-167) YP_069553.1 similar to Yersinia pestis YPO3098 wbyL; probable glycosyltransferase (100% evalue=1.E-140); Helicobacter pylori HP0102 conserved hypothetical protein (43.8% evalue=6.E-55) YP_069554.1 similar to Yersinia pestis YPO3097 manB, rfbK; phosphomannomutase (99.7% evalue=0); Escherichia coli JW2033 manB; Phosphomannomutase (PMM) (73.6% evalue=0) YP_069555.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake YP_069556.1 similar to Yersinia pestis YPO3095 gsk; inosine-guanosine kinase (100% evalue=0); Salmonella typhimurium STM0491 gsk; inosine-guanosine kinase (84.7% evalue=0) YP_069557.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_069558.1 similar to Yersinia pestis YPO3093 rosA, fsr; membrane efflux protein (99.7% evalue=0); Salmonella typhimurium STM0493 fsr; MFS family of transport protein (77.1% evalue=1.E-171); Citation: Bengoechea and Skurnik (2000) Mol. Microbiol. 37:67-80 YP_069559.1 similar to Yersinia pestis YPO3089 hypothetical protein (100% evalue=5.E-39) YP_069560.1 similar to Yersinia pestis YPO3088 conserved hypothetical protein (99.3% evalue=2.E-84); Escherichia coli b0481 ybaK; hypothetical 17.1 kD protein in ushA-tesA intergenic region (76.7% evalue=9.E-65) YP_069561.1 similar to Yersinia pestis YPO3087 conserved hypothetical protein (100% evalue=1.E-155); Escherichia coli b0482 ybaP; hypothetical 29.9 kD protein in ushA-tesA intergenic region (56.4% evalue=5.E-81) YP_069562.1 similar to Yersinia pestis YPO3086 ybaR; Cu2+-exporting ATPase (99.7% evalue=0); Escherichia coli ECs0537 Cu2+-exporting ATPase (66.3% evalue=0) YP_069563.1 similar to Yersinia pestis YPO3085 cueR; regulatory protein (100% evalue=1.E-75); Salmonella typhimurium STM0499 cueR; heavy metal transcriptional repressor (MerR family) (72.9% evalue=2.E-54) YP_069564.1 similar to Yersinia pestis YPO3084 ybbJ; membrane protein (100% evalue=2.E-84); Escherichia coli JW0477 ybbJ; Hypothetical protein (58.2% evalue=2.E-47) YP_069565.1 similar to Yersinia pestis YPO3083 conserved hypothetical protein (100% evalue=1.E-164); Salmonella typhimurium STM0501 ybbK; inner membrane protein (84.2% evalue=1.E-142) YP_069566.1 similar to Yersinia pestis YPO3082 ybbN; thioredoxin (99.6% evalue=1.E-158); Salmonella typhi STY0550 ybbN; thioredoxin-like protein (71.9% evalue=1.E-114) YP_069567.1 similar to Yersinia pestis YPO3081 ybbO; probable short-chain dehydrogenase (100% evalue=1.E-143); Escherichia coli ECs0556 oxidoreductase (68.3% evalue=5.E-99) YP_069568.1 similar to Yersinia pestis YPO3080 tesA, apeA, pldC; acyl-CoA thioesterase (100% evalue=1.E-120); Escherichia coli b0494 tesA, apeA; acyl-CoA thioesterase I precursor (protease I) (71.1% evalue=3.E-84) YP_069569.1 similar to Yersinia pestis YPO3079 ybbA; ABC transporter ATP-binding protein (99.5% evalue=1.E-123); Escherichia coli ECs0557 ATP-binding component of a transport system (78.9% evalue=1.E-95) YP_069570.1 similar to Yersinia pestis YPO3078 ybbP; permease (99.1% evalue=0); Salmonella typhimurium STM0508 ybbP; inner membrane protein (68.9% evalue=0) YP_069571.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_069572.1 Catalyzes a step in the de novo purine nucleotide biosynthetic pathway YP_069573.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_069574.1 similar to Yersinia pestis YPO3074 ppiB; peptidyl-prolyl cis-trans isomerase B (100% evalue=8.E-94); Escherichia coli b0525 ppiB; peptidyl-prolyl cis-trans isomerase B (ppiase B) (rotamase B) (84.7% evalue=7.E-79) YP_069575.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_069576.1 similar to Yersinia pestis YPO2825 conserved hypothetical protein (100% evalue=9.E-35); Salmonella typhi STY0587 ybcJ; conserved hypothetical protein (72.8% evalue=5.E-23) YP_069577.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_069578.1 similar to Yersinia pestis YPO2823 putativ regulator. 100% identical. YP_069579.1 similar to Yersinia pestis YPO2822 hypothetical protein. 96% identical. YP_069580.1 similar to Yersinia pestis YPO2821 hypothetical protein (98.2% evalue=1.E-61) YP_069581.1 similar to Yersinia pestis YPO2820 hypothetical protein (100% evalue=3.E-61) YP_069583.1 similar to Yersinia pestis YPO2817 CDP-alcohol phosphatidyltransferase (99.5% evalue=1.E-110); Escherichia coli JW1405 hypothetical protein (55.8% evalue=1.E-57) YP_069584.1 similar to Yersinia pestis YPO2816 ynbB; phosphatidate cytidylyltransferase (99.3% evalue=1.E-179); Vibrio cholerae VC1936 phosphatidate cytidylyltransferase, (52.2% evalue=4.E-93) YP_069585.1 similar to Yersinia pestis YPO2815 acyltransferase (100% evalue=1.E-120); Vibrio cholerae VC1937 conserved hypothetical protein (47.8% evalue=2.E-45) YP_069586.1 similar to Yersinia pestis YPO2814 conserved hypothetical protein (99.4% evalue=0); Escherichia coli ECs2012 hypothetical protein (66.2% evalue=0) YP_069587.1 similar to Yersinia pestis YPO2813 ynbD; dual specificity phosphatase (99.5% evalue=0); Escherichia coli JW1408 ynbD; Hypothetical protein (49.5% evalue=1.E-114) YP_069588.1 similar to Yersinia pestis YPO2812 membrane protein (98.3% evalue=4.E-65) YP_069589.1 similar to Yersinia pestis YPO2811 membrane protein (100% evalue=5.E-58) YP_069590.1 similar to Yersinia pestis YPO2807 ptxR; LysR-family transcriptional regulatory protein (99.6% evalue=1.E-169); Xylella fastidiosa XF1752 transcriptional regulator (LysR family) (52.8% evalue=3.E-92) YP_069591.1 similar to Yersinia pestis YPO2806 aldo/keto reductase (100% evalue=0); Sinorhizobium meliloti SMa0563 aldehyde or keto oxidase, probable (64.3% evalue=1.E-113) YP_069592.1 similar to Yersinia pestis YPO2805 aldo/keto reductase (99.6% evalue=1.E-161); Escherichia coli ECs0335 oxidoreductase (91.9% evalue=5.E-98) YP_069593.1 similar to Yersinia pestis YPO2804 hypothetical protein (99.8% evalue=0) YP_069594.1 similar to Yersinia pestis YPO2803 bglB; beta-glucosidase (98.2% evalue=0); Thermotoga maritima TM0025 beta-glucosidase (41.1% evalue=1.E-152) YP_069595.1 similar to Yersinia pestis YPO2802 membrane protein (97.7% evalue=2.E-93); Pasteurella multocida PM0986 unknown (32.9% evalue=8.E-16) YP_069596.1 similar to Yersinia pestis YPO2801 membrane protein (99% evalue=0); Pasteurella multocida PM0986 unknown (25.7% evalue=3.E-13) YP_069597.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_069598.1 similar to Escherichia coli b1128 ycfD; hypothetical 42.6 kD protein in pepT-phoQ intergenic region (67.3% evalue=1.E-154); Escherichia coli JW1114 ycfD; Hypothetical protein (67.3% evalue=1.E-154) YP_069599.1 similar to Yersinia pestis YPO3028 autotransporter (39.1% evalue=1.E-84) YP_069600.1 similar to Yersinia pestis YPO2795 hypothetical protein (100% evalue=4.E-38) YP_069601.1 similar to Yersinia pestis YPO2794 hypothetical protein (98.7% evalue=2.E-40) YP_069602.1 similar to Yersinia pestis YPO2962 conserved hypothetical protein (65.4% evalue=3.E-58) YP_069603.1 similar to Yersinia pestis YPO2590 hypothetical protein, 100% identical YP_069604.1 similar to Yersinia pestis YPO2863 membrane protein (40% evalue=6.E-41) YP_069605.1 similar to Yersinia pestis YPO2785 sfsB, nlp, sfs7; DNA-binding protein (100% evalue=5.E-42); Salmonella typhi STY4673 cII; transcriptional regulatory protein (73.2% evalue=1.E-25) YP_069606.1 similar to Rickettsia conorii RC0249 pbpC; bifunctional penicillin-binding protein 1C (39.7% evalue=1.E-163); Pasteurella multocida PM0644 ponC; bifunctional penicillin-binding protein 1C (45.8% evalue=0) YP_069607.1 similar to Yersinia pestis YPO2573 membrane protein (99.4% evalue=0); Pasteurella multocida PM0659 hypothetical R. prowazekii (38.4% evalue=0) YP_069608.1 similar to Yersinia pestis YPO2576 conserved hypothetical protein (100% evalue=1.E-152); Salmonella typhimurium STM4417 transcriptional regulator (62.8% evalue=2.E-89) YP_069609.1 similar to Yersinia pestis YPO2577 methylmalonate-semialdehyde dehydrogenase (99.6% evalue=0); Salmonella typhimurium STM4421 NAD-dependent aldehyde dehydrogenase (63.8% evalue=0) YP_069610.1 similar to Yersinia pestis YPO2578 thiamine pyrophosphate-dependent protein (99.8% evalue=0); C. perfringens CPE0089 iolD; myo-inositol catabolism protein (56.2% evalue=0) YP_069611.1 similar to Agrobacterium tumefaciens Atu4012 idhA; myo-inositol 2-dehydrogenase (48.9% evalue=1.E-81); Agrobacterium tumefaciens AGR_L_1682 myo-inositol 2-dehydrogenase (48.9% evalue=1.E-81) YP_069612.1 similar to Yersinia pestis YPO2581 sugar-binding periplasmic protein (100% evalue=1.E-171); Caulobacter crescentus CC0859 sugar ABC transporter, periplasmic sugar-binding protein (41% evalue=3.E-63) YP_069613.1 similar to Yersinia pestis YPO2582 sugar transport ATP-binding protein (99% evalue=0); Caulobacter crescentus CC0860 sugar ABC transporter, ATP-binding protein (52.1% evalue=1.E-135) YP_069614.1 similar to Yersinia pestis YPO2583 sugar transport system permease (100% evalue=0); Caulobacter crescentus CC0861 sugar ABC transporter, permease (54.8% evalue=1.E-101) YP_069615.1 similar to Yersinia pestis YPO2584 conserved hypothetical protein (99.2% evalue=0); Sinorhizobium meliloti SMc01163 oxidoreductase (46.5% evalue=2.E-92) YP_069616.1 similar to Yersinia pestis YPO2585 carbohydrate kinase (99.6% evalue=0); Ralstonia solanacearum RS02748 iolC, RSc1240; probable transferase kinase (55.5% evalue=0) YP_069617.1 similar to Yersinia pestis YPO2586 conserved hypothetical protein (99.3% evalue=1.E-176); Mesorhizobium loti mlr2437 rhizopine catabolism protein MocC (52% evalue=1.E-87) YP_069618.1 similar to Yersinia pestis YPO2587 conserved hypothetical protein (98.8% evalue=1.E-161); Salmonella typhimurium STM4420 inner membrane protein (64% evalue=2.E-96) YP_069620.1 similar to Yersinia pestis YPO2588 ABC transport protein (100% evalue=0); Ralstonia solanacearum RS04417 probable composite ATP-binding transmembrane ABC transporter protein (53.8% evalue=1.E-180) YP_069621.1 similar to Yersinia pestis YPO2589 conserved hypothetical protein (100% evalue=8.E-52); Clostridium acetobutylicum CAC3394 uncharacterized conserved protein, YGIN family (40% evalue=1.E-11) YP_069622.1 similar to Yersinia pestis YPO2591 hypothetical protein (75% evalue=1.E-16) YP_069623.1 similar to Yersinia pestis YPO4045 membrane protein (24% evalue=2.E-08) YP_069624.1 similar to Yersinia pestis YPO2593 LuxR-family regulatory proteins (100% evalue=1.E-111) YP_069625.1 similar to Yersinia pestis YPO2594 hypothetical protein (99.1% evalue=5.E-62) YP_069626.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_069627.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_069628.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_069629.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_069630.2 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_069631.1 similar to Yersinia pestis YPO2600 conserved hypothetical protein (100% evalue=2.E-44); Salmonella typhimurium STM0636 ybeD; cytoplasmic protein (83.9% evalue=7.E-37) YP_069632.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_069633.1 similar to Yersinia pestis YPO2602 rlpA; rare lipoprotein A precursor (100% evalue=0); Salmonella typhimurium STM0638 rlpA; a minor lipoprotein (55% evalue=1.E-100) YP_069634.1 similar to Yersinia pestis YPO2603 rodA, mrdB; rod shape-determining protein (100% evalue=0); Escherichia coli Z0780 mrdB; rod shape-determining membrane protein (85.9% evalue=0) YP_069635.1 similar to Yersinia pestis YPO2604 pbpA, mrdA; penicillin-binding protein 2 (99.5% evalue=0); Salmonella typhimurium STM0640 mrdA; cell elongation specific transpeptidase of penicillin-binding protein 2 (peptidoglycan synthetase) (80.7% evalue=0) YP_069636.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_069637.1 similar to Yersinia pestis YPO2606 conserved hypothetical protein (99% evalue=4.E-54); Salmonella typhimurium STM0642 ybeB; ACR, homolog of plant Iojap protein (84.7% evalue=2.E-48) YP_069638.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_069639.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_069640.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_069641.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_069642.1 similar to Yersinia pestis YPO2611 conserved hypothetical protein (100% evalue=1.E-90); Salmonella typhi STY0704 ybeL; conserved hypothetical protein (79.3% evalue=2.E-72) YP_069643.1 similar to Yersinia pestis YPO2612 gltL; glutamate/aspartate transport ATP-binding protein (100% evalue=1.E-133); Salmonella typhi STY0707 gltL; glutamate/aspartate transport ATP-binding protein GltL (87.9% evalue=1.E-118) YP_069644.1 similar to Yersinia pestis YPO2613 gltK; glutamate/aspartate transport system permease (100% evalue=1.E-119); Salmonella typhi STY0708 gltK; glutamate/aspartate transport system permease GltK (87.5% evalue=1.E-107) YP_069645.1 similar to Yersinia pestis YPO2614 gltJ; glutamate/aspartate transport system permease (99.5% evalue=1.E-138); Salmonella typhi STY0709 gltJ; glutamate/aspartate transport system permease GltJ (86.9% evalue=1.E-122) YP_069646.1 similar to Yersinia pestis YPO2615 glnH; amino acid-binding protein precursor (100% evalue=1.E-170); Salmonella typhimurium STM0665 gltI; ABC superfamily (bind_prot), glutamate/aspartate transporter (79.6% evalue=1.E-137) YP_069647.1 Transfers the fatty acyl group on membrane lipoproteins YP_069648.1 similar to Yersinia pestis YPO2617 ybeX; membrane protein (100% evalue=1.E-165); Escherichia coli JW0655 ybeX; Hypothteical protein (86.6% evalue=1.E-144) YP_069649.1 similar to Yersinia pestis YPO2618 conserved hypothetical protein (98.7% evalue=7.E-87); Salmonella typhi STY0714 conserved hypothetical protein (79.8% evalue=2.E-67) YP_069650.1 similar to Yersinia pestis YPO2619 conserved hypothetical protein (99.7% evalue=0); Escherichia coli ECs0698 ATP-binding protein in pho regulon (87.2% evalue=1.E-172) YP_069651.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_069652.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_069653.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_069654.1 similar to Yersinia pestis YPO2624 nagD; N-acetylglucosamine metabolism protein (100% evalue=1.E-142); Escherichia coli Z0822 nagD; N-acetylglucosamine metabolism (86% evalue=1.E-126) YP_069655.1 similar to Yersinia pestis YPO2625 nagC, nagR; N-acetylglucosamine regulatory protein (99.7% evalue=0); Salmonella typhi STY0720 nagC; N-acetylglucosamine repressor (77.3% evalue=0) YP_069656.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_069657.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_069658.1 similar to Yersinia pestis YPO2628 nagE, pstN; pts system, N-acetylglucosamine-specific IIABC component (99.8% evalue=0); Pasteurella multocida PM0876 PTS system, N-acetylglucosamine-specific II component (65.9% evalue=0) YP_069659.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_069660.1 similar to Yersinia pestis YPO2631 ybfM; exported protein (99.3% evalue=0); Escherichia coli JW0667 ybfM; Hypothteical protein (68.5% evalue=0) YP_069661.1 similar to Vibrio cholerae VC2217 beta-N-acetylhexosaminidase (57.2% evalue=0); Caulobacter crescentus CC0447 beta-N-acetylhexosaminidase, (25.7% evalue=2.E-39) YP_069662.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_069663.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_069665.1 similar to Yersinia pestis YPO2637 conserved hypothetical protein (100% evalue=9.E-48); Escherichia coli b0685 ybfE; hypothetical 13.9 kD protein in fldA-seqA intergenic region (86.5% evalue=5.E-38) YP_069666.1 similar to Yersinia pestis YPO2638 conserved hypothetical protein (99.2% evalue=1.E-144); Escherichia coli b0686 ybfF; esterase/lipase ybff (66.4% evalue=1.E-97) YP_069667.1 similar to Yersinia pestis YPO2640 trp1400A; IS1400 transposase A (100% evalue=8.E-44); Salmonella typhimurium STM2765 transposase (70.9% evalue=7.E-30) YP_069668.1 similar to Yersinia pestis YPO3591 transposase for insertion sequence IS100 (100% evalue=0) YP_069669.1 similar to Yersinia pestis YPO3592 insertion sequence IS100, ATP-binding protein (100% evalue=1.E-142) YP_069670.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_069671.1 similar to Yersinia pestis YPO1102 conserved hypothetical protein (100% evalue=3.E-78); Escherichia coli Z3912 hypothetical protein (79.1% evalue=2.E-63) YP_069672.1 similar to Yersinia pestis YPO1103 conserved hypothetical protein (98.9% evalue=3.E-46); Escherichia coli b2618 hypothetical protein (76.4% evalue=3.E-32) YP_069673.2 similar to Yersinia pestis YPO1104 conserved hypothetical protein (100% evalue=4.E-61); Salmonella typhimurium STM2685 smpA; small membrane protein A (80.1% evalue=1.E-48) YP_069674.1 similar to Yersinia pestis YPO1105 DNA repair protein RecN (99.8% evalue=0); Escherichia coli JW2597 recN; DNA repair protein RecN (recombination protein n) (74.5% evalue=0) YP_069675.1 catalyzes the phosphorylation of NAD to NADP YP_069676.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_069677.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_069678.1 similar to Yersinia pestis YPO1109 sdhC, cybA; succinate dehydrogenase cytochrome b-556 subunit (99.2% evalue=3.E-67); Escherichia coli b0721 sdhC, cybA; succinate dehydrogenase cytochrome b-556 subunit (77.1% evalue=2.E-51) YP_069679.1 similar to Yersinia pestis YPO1110 sdhD; succinate dehydrogenase hydrophobic membrane anchor protein (100% evalue=2.E-60); Escherichia coli b0722 sdhD; succinate dehydrogenase hydrophobic membrane anchor protein (69.2% evalue=3.E-44) YP_069680.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_069681.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_069682.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_069683.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_069684.1 catalyzes the interconversion of succinyl-CoA and succinate YP_069685.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_069686.1 similar to Yersinia pestis YPO1117 cydA; cytochrome D ubiquinol oxidase subunit I (100% evalue=0); Escherichia coli ECs0768 cytochrome bd-I oxidase subunit I (86.5% evalue=0) YP_069687.1 similar to Yersinia pestis YPO1118 cydB; cytochrome D ubiquinol oxidase subunit II (100% evalue=0); Salmonella typhi STY0787 cydB; cytochrome d ubiquinol oxidase subunit II (79.4% evalue=0) YP_069688.1 similar to Salmonella typhi STY0788 membrane protein (89.6% evalue=1.E-08); Escherichia coli JW0724 ybgT, ybgE; Hypothetical protein (ORFC) (76.4% evalue=4.E-09) YP_069689.1 similar to Yersinia pestis YPO1119 conserved hypothetical protein (100% evalue=1.E-50); Escherichia coli ECs0770 hypothetical protein (59.5% evalue=4.E-27) YP_069690.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_069691.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_069692.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_069693.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_069694.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_069695.1 similar to Yersinia pestis YPO1125 pal, excC; peptidoglycan-associated lipoprotein Pal (99.4% evalue=2.E-89); Escherichia coli JW0731 pal; Peptidoglycan-associated lipoprotein precursor (83.8% evalue=5.E-75) YP_069696.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_069697.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_069698.1 similar to Yersinia pestis YPO1128 pnuC; intergral membrane NMN transport protein PnuC (100% evalue=1.E-138); Salmonella typhimurium STM0757 pnuC; NMN family, nucleoside/purine/pyrimidine transporter (77.3% evalue=1.E-104) YP_069699.1 involved in zinc efflux across the cytoplasmic membrane YP_069700.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_069701.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_069702.1 similar to Yersinia pestis YPO1134 psiF; starvation-inducible protein (99% evalue=2.E-58); Salmonella typhimurium STM0384 psiF; induced by phosphate starvation (53.5% evalue=9.E-26) YP_069703.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_069704.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_069705.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_069706.1 similar to Yersinia pestis YPO1139 galE, galD; UDP-glucose 4-epimerase (99.4% evalue=0); Escherichia coli b0759 galE, galD; UDP-glucose 4-epimerase (galactowaldenase) (UDP-galactose 4-epimerase) (76.3% evalue=1.E-151) YP_069707.1 similar to Yersinia pestis YPO1140 membrane protein (100% evalue=1.E-153); Pseudomonas aeruginosa PA5132 hypothetical protein (62.7% evalue=1.E-93) YP_069708.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_069709.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_069711.1 with ModCB is involved in the high-affinity transport of molybdate YP_069712.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_069713.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_069714.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_069715.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_069716.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_069717.1 similar to Yersinia pestis YPO1151 bioB; biotin synthase (100% evalue=0); Escherichia coli JW0758 bioB; biotin synthetase (84.5% evalue=1.E-170) YP_069718.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_069719.1 similar to Yersinia pestis YPO1153 bioC; biotin synthesis protein BioC (99.6% evalue=1.E-155); Salmonella typhimurium STM0796 bioC; biotin biosynthesis; reaction prior to pimeloyl CoA (50.4% evalue=3.E-61) YP_069720.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_069721.1 similar to Yersinia pestis YPO1155 amino acid transporter (100% evalue=1.E-135); Ralstonia solanacearum RS03602 probable ATP-binding ABC transporter protein (46.3% evalue=5.E-51) YP_069722.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_069723.1 similar to Yersinia pestis YPO1157 conserved hypothetical protein (100% evalue=5.E-42); Vibrio cholerae VC1816 hypothetical protein (70.4% evalue=4.E-21) YP_069724.1 similar to Yersinia pestis YPO1158 conserved hypothetical protein (100% evalue=1.E-169); Salmonella typhimurium STM0801 ybhK; cytoplasmic protein (79.4% evalue=1.E-133) YP_069725.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_069726.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_069727.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_069728.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_069729.1 similar to Yersinia pestis YPO1163 membrane protein (99.5% evalue=1.E-129); Salmonella typhimurium STM0807 ybhL; permease (76.6% evalue=2.E-97) YP_069730.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_069731.1 catalyzes the formation of betaine from betaine aldehyde YP_069732.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_069733.1 proton-motive-force-driven choline transporter YP_069734.1 similar to Yersinia pestis YPO1169 LysR-family regulatory protein (100% evalue=1.E-169); Salmonella typhi STY2655 xapR; xanthosine operon transcriptional regulator (39.3% evalue=2.E-52) YP_069735.1 similar to Yersinia pestis YPO1170 membrane protein (98.9% evalue=1.E-159); Bacillus subtilis BG10039 yyaM; similar to unknown proteins (20.1% evalue=4.E-19) YP_069736.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_069737.1 similar to Escherichia coli b2406 xapB; xanthosine permease (xanthosine transporter) (65.5% evalue=1.E-163); Escherichia coli JW2397 xapB; Xanthosine permease (xanthosine transporter) (65.5% evalue=1.E-163) YP_069738.1 similar to Salmonella typhi STY3713 possible exported protein (36% evalue=2.E-17); Salmonella typhimurium STM4172 zraP; zinc-resistance associated protein (36% evalue=2.E-17) YP_069739.1 similar to Salmonella typhi STY3712 hydH; two-component system sensor protein (56.4% evalue=4.E-70) YP_069740.1 similar to Escherichia coli b4004 hydG; transcriptional regulatory protein hydG (63.9% evalue=1.E-160); Escherichia coli JW3968 hydG; Transcriptional regulatory protein HydG. (63.9% evalue=1.E-160) YP_069741.1 similar to Ralstonia solanacearum RS02674 probable flavoprotein NADH-dependent oxidoreductase (51.2% evalue=5.E-96); Pseudomonas aeruginosa PA2932 morB; morphinone reductase (50.2% evalue=2.E-96) YP_069742.1 similar to Sinorhizobium meliloti SMc01817 transcription regulator protein (42.7% evalue=3.E-60); Mesorhizobium loti mlr2579 probable transcriptional regulator (46.2% evalue=4.E-65) YP_069744.1 similar to Escherichia coli ECs0870 hypothetical protein (85.5% evalue=1.E-178); Escherichia coli b0792 ybhR; ABC-2 type transport system permease (85.5% evalue=1.E-178) YP_069745.1 similar to Salmonella typhi STY0851 inner membrane protein (79.5% evalue=1.E-164); Salmonella typhimurium STM0816 ybhS; ABC superfamily (membrane) transport protein (79.5% evalue=1.E-164) YP_069746.1 similar to Escherichia coli b0794 ybhF; ABC-2 type transport system ATP-binding protein (74.5% evalue=0); Escherichia coli JW0778 yhiG; Hypothetical ABC transporter ATP-binding protein (74.5% evalue=0) YP_069747.1 similar to Salmonella typhi STY0853 HlyD-family secretion protein (66.5% evalue=1.E-122); Escherichia coli ECs0873 membrane protein (66.7% evalue=1.E-121) YP_069748.1 similar to Escherichia coli b0796 ybiH; hypothetical transcriptional regulator in moaE-rhlE intergenic region (52.5% evalue=1.E-56); Escherichia coli Z1016 ybiH; transcriptional regulator (52.5% evalue=1.E-56) YP_069749.1 this helicase is not essential cell growth YP_069750.1 similar to Yersinia pestis YPO1174 hypothetical protein (92.1% evalue=1.E-122) YP_069751.1 similar to Yersinia pestis YPO1175 conserved hypothetical protein (100% evalue=1.E-179); Escherichia coli ECs3026 regulator protein (83.6% evalue=1.E-153) YP_069752.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_069753.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_069754.1 similar to Yersinia pestis YPO1178 cyaB; adenylate cyclase 2 (100% evalue=2.E-99); Methanocaldococcus jannaschii MJ0240 hypothetical protein MJ0240 (27.4% evalue=6.E-09) YP_069755.1 similar to Yersinia pestis YPO1179 conserved hypothetical protein (100% evalue=7.E-66); Salmonella typhi STY0449 yajD; conserved hypothetical protein (84% evalue=1.E-56) YP_069756.1 similar to Yersinia pestis YPO1180 hypothetical protein (99.7% evalue=0) YP_069757.1 similar to Yersinia pestis YPO1181 membrane protein (100% evalue=6.E-41); Escherichia coli JW1784 hypothetical protein (82.9% evalue=2.E-35) YP_069758.1 similar to Yersinia pestis YPO1182 ABC transport ATP-binding subunit (100% evalue=1.E-156); Agrobacterium tumefaciens Atu0174 phnC; ABC transporter, nucleotide binding/ATPase [phosphonate] (47.8% evalue=1.E-57) YP_069759.1 similar to Yersinia pestis YPO1183 substrate-binding periplasmic transport protein (99.3% evalue=1.E-176); Sinorhizobium meliloti SMb21176 phoD; phosphate uptake ABC transporter periplasmic solute-binding protein precursor (39.2% evalue=2.E-51) YP_069760.1 similar to Yersinia pestis YPO1184 ABC transport membrane permease (99.6% evalue=1.E-147); Agrobacterium tumefaciens AGR_C_285 phoE; phosphate uptake ABC transporter permease (34.4% evalue=3.E-38) YP_069761.1 similar to Yersinia pestis YPO1185 ABC transport membrane permease (100% evalue=1.E-166); Agrobacterium tumefaciens AGR_C_284 PhoT (43% evalue=1.E-41) YP_069762.1 similar to Yersinia pestis YPO1186 conserved hypothetical protein (99.3% evalue=3.E-85); Pseudomonas aeruginosa PA0915 conserved hypothetical protein (55.5% evalue=5.E-44) YP_069763.1 similar to Yersinia pestis YPO1187 substrate-binding periplasmic transport protein (100% evalue=0); Pseudomonas aeruginosa PA4858 conserved hypothetical protein (80.2% evalue=0) YP_069764.1 similar to Yersinia pestis YPO1188 Branched-chain amino acid transport system, permease component (100% evalue=0); Pseudomonas aeruginosa PA4859 probable permease of ABC transporter (84.8% evalue=1.E-151) YP_069765.1 similar to Yersinia pestis YPO1189 Branched-chain amino acid transport system, permease component (100% evalue=0); Pseudomonas aeruginosa PA4860 probable permease of ABC transporter (77.5% evalue=1.E-166) YP_069766.1 similar to Yersinia pestis YPO1190 ABC transport ATP-binding subunit (99.6% evalue=1.E-155); Pseudomonas aeruginosa PA4861 probable ATP-binding component of ABC transporter (76.4% evalue=1.E-100) YP_069767.1 similar to Yersinia pestis YPO1191 ABC transport ATP-binding subunit (99.1% evalue=1.E-129); Pseudomonas aeruginosa PA4862 probable ATP-binding component of ABC transporter (77.1% evalue=1.E-100) YP_069768.1 similar to Yersinia pestis YPO1192 conserved hypothetical protein (98.2% evalue=1.E-164); B. halodurans BH2933 unknown (24.7% evalue=1.E-10) YP_069769.1 similar to Yersinia pestis YPO1193 pyridoxal-dependent decarboxylase (99.7% evalue=0); A. thalianan At2g20340 F11A3.11; tyrosine decarboxylase (38.3% evalue=2.E-92) YP_069770.1 similar to Yersinia pestis YPO1194 sulfurtransferase (99.6% evalue=1.E-163); Escherichia coli JW2505 sseA; thiosulfate sulfurtransferase (rhodanese-like protein). (50.5% evalue=1.E-79) YP_069771.1 similar to Salmonella typhi STY2395 yehZ; periplasmic protein (71.1% evalue=1.E-120); Salmonella typhimurium STM2165 yehZ; ABC superfamily transport protein (possibly glycine betaine choline transport for osmoprotection) (71.1% evalue=1.E-120) YP_069772.1 similar to Yersinia pestis YPO1197 ABC transport integral membrane subunit (100% evalue=0); Escherichia coli Z3379 yehY; transport system permease (52.3% evalue=1.E-105) YP_069773.1 similar to Yersinia pestis YPO1198 ABC transport ATP-binding subunit (99.6% evalue=1.E-175); Salmonella typhimurium STM2163 yehX; ABC-type proline/glycine betaine transport system, ATPase component (68% evalue=1.E-112) YP_069774.1 similar to Yersinia pestis YPO1199 ABC transport integral membrane subunit (100% evalue=1.E-153); Salmonella typhi STY2392 yehW; permease transmembrane component (67% evalue=6.E-83) YP_069775.1 similar to Yersinia pestis YPO1200 amino acid permease (99.7% evalue=0); Salmonella typhi STY4493 amino acid permease (88.1% evalue=0) YP_069776.1 similar to Yersinia pestis YPO1201 arginine decarboxylase (99.8% evalue=0); Escherichia coli Z5719 adiA; biodegradative arginine decarboxylase (52.4% evalue=0) YP_069778.1 similar to Yersinia pestis YPO1203 membrane protein (99.3% evalue=1.E-162); Salmonella typhi STY2198 yedA; membrane protein (68.9% evalue=1.E-110) YP_069779.1 similar to Yersinia pestis YPO1205 ompC2; outer membrane protein C2 (99.4% evalue=0); Escherichia coli b1377 outer membrane protein (62.4% evalue=1.E-135) YP_069780.1 helicase involved in DNA repair and perhaps also replication YP_069781.1 similar to Yersinia pestis YPO1207 katA; catalase (100% evalue=0); Pseudomonas aeruginosa PA4236 katA; catalase (80.3% evalue=0) YP_069782.1 similar to Yersinia pestis YPO1208 exported protein (99.4% evalue=2.E-98); Escherichia coli Z3508 hypothetical protein (51.1% evalue=9.E-55) YP_069783.1 similar to Yersinia pestis YPO1209 tyrP; tyrosine-specific transport protein (99.7% evalue=0); Escherichia coli JW1895 tyrP; Tyrosine-specific transport protein (tyrosine permease) (79.1% evalue=0) YP_069785.1 similar to Yersinia pestis YPO1210 conserved hypothetical protein (99.7% evalue=0); Salmonella typhi STY2523 conserved hypothetical protein (59.9% evalue=1.E-137) YP_069786.1 serine protease inhibitor, inhibits trypsin and other proteases YP_069787.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_069788.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_069789.1 Catalyzes the rate-limiting step in dNTP synthesis YP_069790.1 Involved in ubiquinone biosynthesis YP_069791.1 negatively supercoils closed circular double-stranded DNA YP_069792.1 similar to Yersinia pestis YPO1217 rcsC; two component sensor kinase/response regulator protein RcsC (99.8% evalue=0); Salmonella typhi STY2496 rcsC; sensor protein RcsC (58% evalue=0) YP_069793.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_069794.1 similar to Salmonella typhi STY2494 yojN; two-component system sensor kinase (46.4% evalue=0); Salmonella typhimurium STM2269 yojN; sensor/kinase in regulatory system (46.5% evalue=0) YP_069795.1 similar to Yersinia pestis YPO1221 membrane protein (100% evalue=0); Agrobacterium tumefaciens AGR_C_4938 probable transport protein (36.8% evalue=6.E-59) YP_069796.1 allows for ions and hydrophilic solutes to cross the outer membrane YP_069797.1 this protein has no known enzymatic function YP_069798.1 similar to Yersinia pestis YPO1226 transport protein (99.5% evalue=0); Clostridium acetobutylicum CAC0357 permease of the Na:galactoside symporter family (37.6% evalue=4.E-96) YP_069799.1 similar to Yersinia pestis YPO1228 conserved hypothetical protein (99.7% evalue=0); Ralstonia solanacearum RS02069 conserved hypothetical protein (41.1% evalue=1.E-67) YP_069800.1 similar to Yersinia pestis YPO1229 tsr2, cheD2; methyl-accepting chemotaxis protein (100% evalue=0); Ralstonia solanacearum RS04837 methyl-accepting chemotaxis transmembrane protein (55.3% evalue=1.E-180) YP_069801.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA YP_069802.1 similar to Yersinia pestis YPO1232 msgA, dinI; stress response protein (100% evalue=9.E-40); Salmonella typhi STY1883 msgA; virulence protein (61.8% evalue=1.E-20) YP_069803.1 similar to Yersinia pestis YPO1233 prophage repressor protein (100% evalue=1.E-135); Escherichia coli ECs0274 repressor protein CI (47.6% evalue=1.E-56) YP_069804.1 similar to Yersinia pestis YPO1234 probable phage antitermination protein Q (100% evalue=6.E-88); Salmonella typhimurium STM2239 phage protein; homology to antiterminator protein Q of phage P5 (60.8% evalue=3.E-37) YP_069805.1 similar to Yersinia pestis YPO1235 conserved hypothetical protein (99.3% evalue=0); Brucella melitensis BMEII1091 hypothetical pyridoxal phosphate biosynthesis protein (46.1% evalue=1.E-103) YP_069806.1 similar to Yersinia pestis YPO1237 transcriptional regulatory protein (100% evalue=1.E-150); Pasteurella multocida PM1367 glycerol-3 phosphate regulon, (47.6% evalue=2.E-57) YP_069807.1 similar to Yersinia pestis YPO1238 conserved hypothetical protein (99.6% evalue=1.E-148); Salmonella typhimurium STM2915 ygbM; endonuclease (46.2% evalue=7.E-60) YP_069808.1 similar to Yersinia pestis YPO1239 bacteriophage protein (98.9% evalue=3.E-48) YP_069809.1 similar to Yersinia pestis YPO1240 ATP-binding protein (100% evalue=1.E-110) YP_069810.1 similar to Yersinia pestis YPO1241 bacteriophage protein (100% evalue=6.E-31); Escherichia coli ECs4978 hypothetical protein (44.6% evalue=4.E-07) YP_069811.1 similar to Yersinia pestis YPO1242 bacteriophage tail sheath protein (100% evalue=0); H. influenzae HI1511 hypothetical protein HI1511 (40% evalue=1.E-93) YP_069812.1 similar to Yersinia pestis YPO1243 hypothetical protein, 99% identical YP_069813.1 similar to Yersinia pestis YPO1244 hypothetical protein (100% evalue=3.E-50) YP_069814.1 similar to Yersinia pestis YPO1245 bacteriophage coat protein (100% evalue=0) YP_069815.1 similar to Yersinia pestis YPO1246 bacteriophage protein (99.1% evalue=0); H. influenzae HI1515 muN; N protein (25.2% evalue=2.E-15) YP_069816.1 similar to Yersinia pestis YPO1247 bacteriophage tail protein (99.7% evalue=0); Escherichia coli ECs4984 tail protein (29.2% evalue=3.E-31) YP_069817.1 similar to Yersinia pestis YPO1248 bacteriophage (baseplate assembly) protein (100% evalue=1.E-108); Neisseria meningitidis NMB1111 baseplate assembly protein V, (36.9% evalue=1.E-12) YP_069818.1 similar to Yersinia pestis YPO1249 bacteriophage protein GP46 (100% evalue=9.E-83); Escherichia coli ECs4986 hypothetical protein (42.1% evalue=6.E-20) YP_069819.1 similar to Yersinia pestis YPO1250 bacteriophage protein (99.7% evalue=0); H. influenzae HI1520 hypothetical protein HI1520 (29.4% evalue=1.E-30) YP_069820.1 similar to Yersinia pestis YPO1251 bacteriophage protein (100% evalue=4.E-63) YP_069821.1 similar to Yersinia pestis YPO1252 stf; bacteriophage tail fiber protein (95.2% evalue=4.E-52); Escherichia coli JW2351 yfdL; Hypothetical protein (34.9% evalue=2.E-13) YP_069822.1 similar to Salmonella typhi STY4610 phage tail fibre protein (35.5% evalue=2.E-08); Salmonella typhi STY3693 conserved hypothetical protein (30.7% evalue=4.E-11) YP_069823.1 similar to Yersinia pestis YPO1253 LacI-family regulatory protein (100% evalue=1.E-137); B. halodurans BH0181 unknown conserved protein (46.2% evalue=2.E-58) YP_069824.1 similar to Yersinia pestis YPO1254 bglA; 6-phospho-beta-glucosidase (100% evalue=0); Salmonella typhimurium STM3051 bglA; 6-phospho-beta-glucosidase A (79% evalue=0) YP_069825.1 similar to Yersinia pestis YPO1255 hypothetical protein (100% evalue=1.E-64) YP_069827.1 similar to Yersinia pestis YPO0872 hypothetical protein (87.5% evalue=1.E-33) YP_069828.1 similar to Yersinia pestis YPO1260 membrane protein (100% evalue=0); Salmonella typhi STY2466 yejM; sulphatase (63.5% evalue=0) YP_069829.1 similar to Yersinia pestis YPO1261 conserved hypothetical protein (100% evalue=4.E-35); Salmonella typhimurium STM2227 yejL; cytoplasmic protein (81.3% evalue=6.E-29) YP_069830.1 similar to Yersinia pestis YPO1262 nucleoid-associated protein (99.7% evalue=0); Salmonella typhi STY2463 yejK; nucleoid-asociated protein (78.4% evalue=1.E-147) YP_069831.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_069832.1 similar to Yersinia pestis YPO1265 DEAD box helicase family protein (99.6% evalue=0); Salmonella typhi STY2460 yejH; helicase (77.9% evalue=0) YP_069833.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_069834.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_069835.1 similar to Yersinia pestis YPO1269 conserved hypothetical protein (98.2% evalue=4.E-61); Escherichia coli JW2169 yejG; Hypothetical protein (55.2% evalue=2.E-29) YP_069836.1 similar to Yersinia pestis YPO1270 ABC transporter ATP-binding subunit (99.6% evalue=0); Salmonella typhimurium STM2219 yejF; ATPase component of ABC-type transport system, contain duplicated ATPase domain (71.4% evalue=0) YP_069837.1 similar to Yersinia pestis YPO1271 ABC transporter integral membrane subunit (100% evalue=0); Escherichia coli ECs3071 transport system permease (78.4% evalue=1.E-158) YP_069838.1 similar to Yersinia pestis YPO1272 ABC transporter integral membrane subunit (99.7% evalue=0); Escherichia coli ECs3070 transport system permease (80.8% evalue=1.E-171) YP_069839.1 similar to Yersinia pestis YPO1273 substrate-binding transport protein (99.8% evalue=0); Escherichia coli JW2165 yejA; Hypothetical protein (68.1% evalue=0) YP_069840.1 similar to Yersinia pestis YPO1274 membrane protein (100% evalue=0); Salmonella typhi STY2451 rtn; rtn protein (42.8% evalue=1.E-119) YP_069841.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_069842.1 similar to Yersinia pestis YPO1276 membrane protein (99.1% evalue=1.E-131); Escherichia coli Z3433 hypothetical protein (62.1% evalue=5.E-82) YP_069843.1 similar to Yersinia pestis YPO1277 cobalamin synthesis protein (99% evalue=0); Escherichia coli b2173 yeiR; hypothetical 36.1 kD protein in fruB-rtn intergenic region (67.5% evalue=1.E-124) YP_069844.1 similar to Yersinia pestis YPO1278 membrane protein, 100% identical YP_069845.1 similar to Yersinia pestis YPO1279 transcriptional regulatory protein (100% evalue=1.E-140); H. influenzae HI0054 uxuR; uxu operon regulator (52.6% evalue=3.E-66) YP_069846.1 similar to Yersinia pestis YPO1280 D-mannonate oxidoreductase (99.7% evalue=0); Escherichia coli ECs3064 oxidoreductase (64.8% evalue=0) YP_069847.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_069848.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_069849.1 similar to Yersinia pestis YPO1285 mtr; tryptophan-specific transport protein (100% evalue=0); Pseudomonas aeruginosa PA5434 mtr; tryptophan permease (59.6% evalue=1.E-139) YP_069850.1 similar to Yersinia pestis YPO1286 conserved hypothetical protein (98.8% evalue=1.E-45); Escherichia coli JW2158 hypothetical protein (66.6% evalue=1.E-28) YP_069851.1 similar to Yersinia pestis YPO1287 short chain oxidoreductase (99.2% evalue=1.E-150); Sinorhizobium meliloti SMc02034 oxidoreductase (61% evalue=6.E-80) YP_069852.1 similar to Yersinia pestis YPO1288 D-isomer specific 2-hydroxyacid dehydrogenase family protein (99.6% evalue=1.E-177); Mycobacterium tuberculosis Rv2996c serA; D-3-phosphoglycerate dehydrogenase (39.1% evalue=4.E-47) YP_069853.1 similar to Yersinia pestis YPO1289 conserved hypothetical protein (98.6% evalue=0); Agrobacterium tumefaciens AGR_C_4970 transcription induced by xylose (54.3% evalue=1.E-105) YP_069854.1 similar to Yersinia pestis YPO1290 aldehyde dehydrogenase (99.1% evalue=0); Salmonella typhimurium STM2791 gabD; succinate-semialdehyde dehydrogenase I, NADP-dependent (44.4% evalue=1.E-111) YP_069855.1 similar to Yersinia pestis YPO1291 carbohydrate kinase (99.4% evalue=0); Clostridium acetobutylicum CAC2612 xylB; xylulose kinase (38.9% evalue=1.E-103) YP_069856.1 similar to Yersinia pestis YPO1292 rpiA; ribose 5-phosphate isomerase (100% evalue=1.E-136); Mesorhizobium loti mll0526 ribose 5-phosphate isomerase (44.5% evalue=2.E-42) YP_069857.1 similar to Yersinia pestis YPO1293 periplasmic carbohydrate-binding transport protein (99.7% evalue=0); Salmonella typhi STY3894 rbsB; D-ribose-binding periplasmic protein (26.8% evalue=8.E-20) YP_069858.1 similar to Yersinia pestis YPO1294 ABC transport ATP-binding subunit (99.2% evalue=0); Agrobacterium tumefaciens AGR_C_5112 ABC transporter protein, ATP binding component (38.8% evalue=9.E-82) YP_069859.1 similar to Yersinia pestis YPO1295 ABC transport integral membrane subunit (99.6% evalue=0); Lactococcus lactis L83296 rbsC; ribose ABC transporter permease (37.8% evalue=2.E-52) YP_069860.1 similar to Yersinia pestis YPO1296 Mut family protein (100% evalue=3.E-88); Pseudomonas aeruginosa PA2769 hypothetical protein (39.8% evalue=8.E-18) YP_069861.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_069862.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_069863.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_069864.1 similar to Yersinia pestis YPO1301 psaE; regulatory protein (100% evalue=1.E-118) YP_069865.1 similar to Yersinia pestis YPO1302 psaF; membrane protein (100% evalue=2.E-90) YP_069866.1 similar to Yersinia pestis YPO1303 psaA; pH 6 antigen precursor (antigen 4) (adhesin) (100% evalue=6.E-91) YP_069867.1 similar to Yersinia pestis YPO1304 psaB; chaperone protein PsaB precursor (100% evalue=1.E-158); Salmonella typhimurium STM0300 safB; fimbriae assembly chaparone (45.4% evalue=1.E-54) YP_069868.1 similar to Yersinia pestis YPO1305 psaC; outer membrane usher protein PsaC precursor (100% evalue=0); Salmonella typhi STY0336 safC; outer-membrane fimbrial usher protein (46.3% evalue=0) YP_069869.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_069870.1 similar to Yersinia pestis YPO1307 membrane protein (100% evalue=0); Escherichia coli JW2145 yeiH; Hypothetical protein (66.3% evalue=1.E-121) YP_069871.1 similar to Yersinia pestis YPO1308 LysR-family transcriptional regulatory protein (100% evalue=1.E-162); Salmonella typhimurium STM2201 yeiE; transcriptional regulator, LysR family (73.8% evalue=1.E-119) YP_069872.1 similar to Yersinia pestis YPO1309 lysP, cadR; lysine-specific permease (100% evalue=0); Escherichia coli ECs3048 lysine-specific permease (87.6% evalue=0) YP_069873.1 similar to Yersinia pestis YPO1310 periplasmic substrate-binding transport protein (99.7% evalue=0); Agrobacterium tumefaciens Atu3391 ABC transporter, substrate binding protein [iron] (37.5% evalue=9.E-76) YP_069874.1 similar to Yersinia pestis YPO1311 FecCD-family membrane transport protein (100% evalue=0); Salmonella typhi STY0802 ABC transporter permease (FecCD_family) (72.8% evalue=1.E-141) YP_069875.1 similar to Yersinia pestis YPO1312 siderophore ABC transporter, ATP-binding subunit (99.6% evalue=1.E-144); Salmonella typhimurium STM0771 ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component (72.4% evalue=1.E-103) YP_069876.1 YiuR; outer membrane siderophore receptor YP_069877.1 similar to Yersinia pestis YPO1314 glutathione S-transferase-family protein (99.5% evalue=1.E-119); Pseudomonas aeruginosa PA2813 probable glutathione S-transferase (51.4% evalue=6.E-65) YP_069878.1 similar to Yersinia pestis YPO1315 hydrolase (100% evalue=1.E-125); Pseudomonas aeruginosa PA1143 hypothetical protein (42.2% evalue=4.E-39) YP_069879.1 similar to Yersinia pestis YPO1316 iron/ascorbate oxidoreductase family protein (99.7% evalue=0); Mesorhizobium loti mlr6892 hypothetical protein (61.7% evalue=1.E-118) YP_069880.1 similar to Yersinia pestis YPO1317 exported protein (99.2% evalue=1.E-151); Pseudomonas aeruginosa PA3931 conserved hypothetical protein (50.5% evalue=6.E-59) YP_069881.1 similar to Yersinia pestis YPO1318 ABC transport ATP-binding subunit (100% evalue=1.E-180); Mesorhizobium loti mll4792 ABC transporter, ATP-binding protein (51.2% evalue=9.E-79) YP_069882.1 similar to Yersinia pestis YPO1319 ABC transport integral membrane subunit (100% evalue=1.E-119); Ralstonia solanacearum RS04492 probable transmembrane ABC transporter protein (54.6% evalue=4.E-64) YP_069883.1 similar to Yersinia pestis YPO1320 dacC; D-alanyl-D-alanine carboxypeptidase (100% evalue=0); Escherichia coli ECs0919 D-alanyl-D-alanine carboxypeptidase penicillin-binding protein 6 (71.4% evalue=1.E-164) YP_069884.1 similar to Yersinia pestis YPO1321 sdaC, dcrA; serine transporter (99.7% evalue=0); Escherichia coli Z4113 sdaC; probable serine transporter (82.9% evalue=0) YP_069885.1 similar to Yersinia pestis YPO1322 deoR, nucR; deoxyribose operon repressor (100% evalue=1.E-144); Salmonella typhimurium STM0864 deoR; transcriptional repressor for deoxyribose operon (DeoR family) (57.9% evalue=1.E-80) YP_069886.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_069887.1 similar to Yersinia pestis YPO1324 permease (100% evalue=1.E-115); Salmonella typhimurium STM0865 ybjG; permease (57.5% evalue=9.E-68) YP_069888.1 similar to Yersinia pestis YPO1325 membrane protein (99.6% evalue=1.E-161); Pseudomonas aeruginosa PA4382 hypothetical protein (34.9% evalue=2.E-28) YP_069889.1 similar to Yersinia pestis YPO1326 TrkA, Potassium channel-family protein (99.8% evalue=0); Salmonella typhimurium STM0870 transport protein (90.8% evalue=0) YP_069890.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_069891.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_069892.1 similar to Yersinia pestis YPO1330 conserved hypothetical protein (100% evalue=4.E-87); Salmonella typhimurium STM0876 ybjN; cytoplasmic protein (68.9% evalue=9.E-58) YP_069893.1 similar to Yersinia pestis YPO1331 potF; putrescine-binding periplasmic protein precursor (100% evalue=0); Escherichia coli JW0838 potF; Putrescine transport protein PotF (85.9% evalue=0) YP_069894.1 part of the PotFGHI ATP-dependent putrescine transporter YP_069895.1 similar to Yersinia pestis YPO1333 potH; putrescine transport system permease (99.3% evalue=0); Salmonella typhimurium STM0879 potH; ABC superfamily (membrane), putrescine transporter (80.6% evalue=1.E-149) YP_069896.1 similar to Yersinia pestis YPO1335 membrane protein (99.3% evalue=3.E-84); Salmonella typhi STY0914 membrane protein (42.3% evalue=4.E-27) YP_069897.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_069898.1 similar to Escherichia coli b0860 artJ; L-arginine transport system substrate-binding protein (78.6% evalue=1.E-110); Escherichia coli JW0844 artJ; Arginine-binding protein ArtJ (78.6% evalue=1.E-110) YP_069899.1 similar to Yersinia pestis YPO1342 SPFH domain protein (100% evalue=1.E-169); Thermotoga maritima TM1823 ftsH protease activity modulator HflC (25% evalue=2.E-14) YP_069900.1 similar to Yersinia pestis YPO1343 periplasmic binding protein (99.4% evalue=0); Agrobacterium tumefaciens Atu3391 ABC transporter, substrate binding protein [iron] (25.3% evalue=4.E-30) YP_069901.1 similar to Yersinia pestis YPO1344 FecCD transport family protein (100% evalue=1.E-83); Sinorhizobium meliloti SMb21430 iron ABC transporter permease (47.9% evalue=3.E-82) YP_069902.1 similar to Yersinia pestis YPO1345 transport ATP-binding protein (100% evalue=1.E-147); Agrobacterium tumefaciens Atu3388 fecE; ABC transporter, nucleotide binding/ATPase [iron] (36.2% evalue=6.E-36) YP_069903.1 similar to Yersinia pestis YPO1346 conserved hypothetical protein (98.8% evalue=1.E-146); Pseudomonas aeruginosa PA4836 hypothetical protein (33.7% evalue=1.E-30) YP_069904.1 similar to Yersinia pestis YPO1347 exported protein (100% evalue=0); Pseudomonas aeruginosa PA4835 hypothetical protein (40% evalue=9.E-81) YP_069905.1 similar to Yersinia pestis YPO1348 membrane protein (99.6% evalue=1.E-155); Pseudomonas aeruginosa PA4834 hypothetical protein (55.9% evalue=3.E-86) YP_069906.1 with ArtPQJI acts to transport arginine across the inner membrane YP_069907.1 with ArtPMJI transports arginine across the inner membrane YP_069908.1 similar to Yersinia pestis YPO1351 artI; arginine-binding periplasmic protein 1 precursor (100% evalue=1.E-136); Salmonella typhimurium STM0890 artI; ABC superfamily (bind_prot), arginine transport system (74.8% evalue=1.E-106) YP_069909.1 With ArtMQJI transports arginine across the inner membrane YP_069910.1 catalyzes the interconversion of chorismate to prephenate YP_069911.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_069912.1 similar to Yersinia pestis YPO1355 conserved hypothetical protein (100% evalue=0); Salmonella typhimurium STM0932 nucleoside-diphosphate-sugar epimerase (74.4% evalue=1.E-146) YP_069913.1 similar to Yersinia pestis YPO1356 membrane protein (99.7% evalue=0); Salmonella typhimurium STM0933 ybjT; nucleoside-diphosphate-sugar epimerase (63.2% evalue=1.E-172) YP_069914.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine YP_069915.1 catalyzes the formation of acetate from pyruvate YP_069916.1 similar to Yersinia pestis YPO1359 hcr; oxidoreductase (99.7% evalue=0); Escherichia coli JW0856 hcr; NADH oxidoreductase for the HCP (59.5% evalue=1.E-104) YP_069917.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_069918.1 similar to Yersinia pestis YPO1361 membrane protein (99.6% evalue=1.E-163); Salmonella typhimurium STM0938 ybjE; inner membrane protein (73.1% evalue=1.E-119) YP_069919.1 similar to Yersinia pestis YPO1362 conserved hypothetical protein (100% evalue=0); Escherichia coli b0876 ybjD; hypothetical 63.6 kD protein in aqpZ-cspD intergenic region (64.4% evalue=0) YP_069920.1 similar to Yersinia pestis YPO1363 virulence factor (100% evalue=0); Escherichia coli b0877 ybjX; hypothetical 38.4 kD protein in aqpZ-cspD intergenic region (46.3% evalue=8.E-74) YP_069921.1 confers macrolide resistance via active drug efflux YP_069922.1 with MacA is involved in the export of macrolide YP_069923.1 similar to Yersinia pestis YPO1366 cspD, cspH; cold shock-like protein (100% evalue=5.E-47); Salmonella typhimurium STM0943 cspD; similar to CspA but not cold shock induced (88.8% evalue=3.E-34) YP_069924.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_069925.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_069926.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_069927.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_069928.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_069929.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_069930.1 similar to Yersinia pestis YPO1374 trxB; thioredoxin reductase (100% evalue=0); Escherichia coli ECs0973 thioredoxin reductase (85% evalue=1.E-156) YP_069931.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_069932.1 similar to Yersinia pestis YPO1376 ftsK; cell division protein (99% evalue=0); Salmonella typhi STY0958 ftsK; cell division protein FtsK (54.2% evalue=0) YP_069933.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_069934.1 similar to Yersinia pestis YPO1378 ATPase (99.7% evalue=0); Escherichia coli JW0875 ycaJ; Hypothetical protein (86.3% evalue=0) YP_069935.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_069936.1 similar to Yersinia pestis YPO1380 membrane protein (100% evalue=0); Escherichia coli Z1244 ycaD; transport (65.9% evalue=1.E-149) YP_069937.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_069938.1 similar to Yersinia pestis YPO1382 hypothetical protein (100% evalue=1.E-131) YP_069939.1 similar to Yersinia pestis YPO1383 pflB, pfl, YPO1383; formate acetyltransferase 1 (100% evalue=0); Escherichia coli JW0886 pflB; Formate c-acetyltransferase. (90.5% evalue=0) YP_069940.1 similar to Yersinia pestis YPO1384 focA; formate transporter 1 (99.6% evalue=1.E-164); Escherichia coli JW0887 focA; probable formate transporter (82.4% evalue=1.E-137) YP_069941.1 similar to Yersinia pestis YPO1385 conserved hypothetical protein (100% evalue=0); Escherichia coli ECs0988 hypothetical protein (80.3% evalue=0) YP_069942.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis YP_069943.1 similar to Yersinia pestis YPO1388 exported protein (37.6% evalue=1.E-57) YP_069944.1 similar to Yersinia pestis YPO1388 exported protein (99% evalue=0) YP_069945.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_069946.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_069947.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_069948.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_069949.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_069950.1 similar to Yersinia pestis YPO1394 membrane protein (99.8% evalue=0); Escherichia coli ECs0996 hypothetical protein (41.8% evalue=1.E-168) YP_069951.1 involved in the transport of lipid A across the inner membrane YP_069952.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_069953.1 similar to Yersinia pestis YPO1397 conserved hypothetical protein (98.9% evalue=0); Sinorhizobium meliloti SMc04383 conserved hypothetical protein (51.5% evalue=1.E-133) YP_069954.1 similar to Yersinia pestis YPO2595 cspE; cold shock protein (57.1% evalue=5.E-14) YP_069955.1 similar to Yersinia pestis YPO1399 conserved hypothetical protein (100% evalue=9.E-30); Salmonella typhimurium STM0987 ycaR; inner membrane protein (77.1% evalue=1.E-21) YP_069956.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_069957.1 similar to Yersinia pestis YPO1401 conserved hypothetical protein (99.3% evalue=1.E-171); Salmonella typhimurium STM0989 mukF protein (killing factor KicB) (54.3% evalue=2.E-93) YP_069958.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_069959.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_069960.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_069961.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_069962.1 similar to Yersinia pestis YPO1407 exported protein (100% evalue=0); Salmonella typhi STY0997 ycbB; exported protein (59.3% evalue=0) YP_069963.1 similar to Yersinia pestis YPO1408 exported protein (100% evalue=1.E-103); Salmonella typhimurium STM0996 ycbK; outer membrane protein (82.4% evalue=3.E-82) YP_069964.1 similar to Yersinia pestis YPO1409 metallo-beta-lactamase superfamily protein (99.5% evalue=1.E-125); Escherichia coli ECs1010 hypothetical protein (71.1% evalue=5.E-94) YP_069965.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_069966.1 similar to Yersinia pestis YPO1411 outer membrane porin C protein (93.6% evalue=0); Salmonella typhimurium STM1473 ompN; outer membrane protein N, non-specific porin (66.2% evalue=1.E-141) YP_069967.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_069968.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_069969.1 similar to Yersinia pestis YPO1414 pepN; aminopeptidase N (99.6% evalue=0); Salmonella typhimurium STM1057 pepN; aminopeptidase N (77.5% evalue=0) YP_069970.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_069971.1 similar to Yersinia pestis YPO1416 conserved hypothetical protein (99.4% evalue=1.E-102); Salmonella typhi STY1080 conserved hypothetical protein (67.6% evalue=2.E-61) YP_069972.1 similar to Yersinia pestis YPO1417 iron-sulfur binding protein (99.7% evalue=0); Escherichia coli Z1297 hypothetical protein (68.8% evalue=1.E-151) YP_069973.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_069974.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_069975.1 similar to Yersinia pestis YPO1420 pqiA; paraquat-inducible protein A (99.2% evalue=0); Escherichia coli JW0933 pqiA; Paraquat-inducible protein A (70.4% evalue=1.E-175) YP_069976.1 similar to Yersinia pestis YPO1421 pqiB; paraquat-inducible protein B (99.8% evalue=0); Salmonella typhi STY1085 pqiB; secreted protein (69.7% evalue=0) YP_069977.1 similar to Yersinia pestis YPO1422 lipoprotein protein (96.9% evalue=1.E-104); Salmonella typhi STY1086 lipoprotein (56% evalue=3.E-59) YP_069978.1 similar to Yersinia pestis YPO1423 hypothetical protein, 100% identical YP_069979.1 similar to Yersinia pestis YPO1423a rmf; ribosome modulation factor (100% evalue=2.E-26); Salmonella typhimurium STM1066 rmf; ribosome modulation factor (involved in dimerization of 70S ribosomes) (81.8% evalue=4.E-21) YP_069980.1 FabF, beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP. YP_069981.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_069982.1 similar to Yersinia pestis YPO1431 Lon protease (99.8% evalue=0); Escherichia coli JW0938 Lon protease (lon) homolog (57.9% evalue=0) YP_069983.1 similar to Yersinia pestis YPO1433 conserved hypothetical protein (100% evalue=3.E-82); Escherichia coli b0956 ycbG; hypothetical 17.7 kD protein in fabA-ompA intergenic region (80% evalue=1.E-64) YP_069984.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_069985.1 similar to Yersinia pestis YPO1436 sulA, sfiA; cell division inhibitor (99.4% evalue=7.E-93); Escherichia coli b0958 sulA, sfiA; cell division inhibitor (60.5% evalue=1.E-41) YP_069986.1 similar to Yersinia pestis YPO1437 conserved hypothetical protein (100% evalue=1.E-117); Escherichia coli b0959 hypothetical protein (44.6% evalue=7.E-34) YP_069987.1 similar to Yersinia pestis YPO1438 membrane protein (99.4% evalue=0); Salmonella typhi STY1095 membrane protein (71.7% evalue=0) YP_069988.1 similar to Yersinia pestis YPO1439 membrane protein (99.3% evalue=2.E-81); Escherichia coli b0961 yccF; hypothetical 16.3 kD protein in sulA-helD intergenic region (78% evalue=6.E-63) YP_069989.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_069990.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_069991.1 similar to Yersinia pestis YPO1442 exported protein (100% evalue=1.E-127); Escherichia coli ECs1048 hypothetical protein (36.2% evalue=4.E-34) YP_069992.1 similar to Yersinia pestis YPO1443 conserved hypothetical protein (100% evalue=2.E-73); Salmonella typhi STY1101 conserved hypothetical protein (72.2% evalue=1.E-51) YP_069993.1 similar to Yersinia pestis YPO1444 conserved hypothetical protein (100% evalue=2.E-57); Salmonella typhi STY1102 conserved hypothetical protein (79% evalue=8.E-43) YP_069994.1 similar to Yersinia pestis YPO1445 conserved hypothetical protein (100% evalue=0); Escherichia coli JW0950 yccW; Hypothetical protein (80.5% evalue=0) YP_069995.1 catalyzes the hydrolysis of acylphosphate YP_069996.1 similar to Yersinia pestis YPO1447 sulfite reductase subunit protein (99% evalue=4.E-58); Escherichia coli ECs1053 sulfite reductase (80.7% evalue=4.E-46) YP_069997.1 similar to Yersinia pestis YPO1451 oxidoreductase (99.7% evalue=0); Mycobacterium tuberculosis_CDC1551MT1824 oxidoreductase, FAD-binding (31.8% evalue=1.E-47) YP_069998.1 similar to Yersinia pestis YPO1452 short chain dehydrogenase (100% evalue=1.E-136); Mesorhizobium loti mlr7055 probable dehydrogenase (44% evalue=7.E-53) YP_069999.1 similar to Yersinia pestis YPO1453 hypothetical protein (100% evalue=1.E-58) YP_070000.1 similar to Yersinia pestis YPO1454 (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydrase (99.3% evalue=4.E-84); C. pneumoniae_J138 fabZ myristoyl-acyl carrier dehydratase (35% evalue=5.E-14) YP_070001.1 similar to Yersinia pestis YPO1455 beta-ketoacyl-[acyl-carrier-protein] synthase (99.2% evalue=0); Neisseria meningitidis NMB0219 3-oxoacyl-(acyl-carrier-protein) synthase II (33.4% evalue=1.E-58) YP_070002.1 similar to Yersinia pestis YPO1456 beta-ketoacyl-[acyl-carrier-protein] reductase (99.5% evalue=1.E-138); B. halodurans BH2491 fabG; 3-oxoacyl-(acyl-carrier protein) reductase (35.7% evalue=5.E-36) YP_070003.1 similar to Yersinia pestis YPO1457 hydroxymethylglutaryl-coenzyme A synthase (100% evalue=0); Bacillus subtilis BG10926 pksG; polyketide biosynthesis protein pksG (34.4% evalue=8.E-56) YP_070004.1 similar to Yersinia pestis YPO1458 enoyl-CoA hydratase (100% evalue=1.E-133); Ralstonia solanacearum RS03234 enoyl-CoA hydratase (25.7% evalue=4.E-14) YP_070005.1 involved in polyketide production YP_070006.1 similar to Yersinia pestis YPO1460 short chain dehydrogenase (100% evalue=1.E-150); Thermoplasma volcanium TVG1417421 3-oxoacyl-acyl carrier protein reductase (27.9% evalue=2.E-15) YP_070007.1 similar to Yersinia pestis YPO1461 hypothetical protein (100% evalue=3.E-83) YP_070008.1 similar to Yersinia pestis YPO1462 acyl carrier protein (100% evalue=6.E-39) YP_070009.1 similar to Yersinia pestis YPO1463 acyl transferase (100% evalue=1.E-158); Bacillus subtilis BG12649 pksC; involved in polyketide synthesis (45% evalue=2.E-60) YP_070010.1 similar to Yersinia pestis YPO1464 hypothetical protein, 100% identical YP_070011.1 similar to Yersinia pestis YPO1465 conserved hypothetical protein (97.5% evalue=5.E-86) YP_070012.1 similar to Yersinia pestis YPO1466 conserved hypothetical protein (99.8% evalue=0) YP_070013.1 similar to Yersinia pestis YPO1467 conserved hypothetical protein (99.1% evalue=0) YP_070014.1 similar to Yersinia pestis YPO1468 membrane protein (99.1% evalue=1.E-132) YP_070015.1 similar to Yersinia pestis YPO1469 exported protein (100% evalue=0) YP_070016.1 similar to Yersinia pestis YPO1470 conserved hypothetical protein (100% evalue=5.E-93) YP_070017.1 similar to Yersinia pestis YPO1471 ATPase subunit of ATP-dependent protease (95.6% evalue=0) YP_070018.1 similar to Yersinia pestis YPO1472 conserved hypothetical protein (96.2% evalue=0) YP_070020.1 similar to Yersinia pestis YPO0982 lipoprotein (77.6% evalue=1.E-55) YP_070021.1 similar to Yersinia pestis YPO1472 conserved hypothetical protein (93.6% evalue=0) YP_070022.1 similar to Salmonella typhi STY3343 exported protein (33% evalue=3.E-10) YP_070024.1 similar to Salmonella typhi STY3285 exported protein (41.1% evalue=7.E-35) YP_070025.1 similar to Yersinia pestis YPO1481 hypothetical protein (98.6% evalue=0) YP_070026.1 similar to Yersinia pestis YPO1482 membrane protein (99.3% evalue=0); Ralstonia solanacearum RS01945 probable transmembrane protein (23.6% evalue=1.E-39) YP_070027.1 similar to Yersinia pestis YPO1483 hypothetical protein (98.8% evalue=0); Pseudomonas aeruginosa PA1656 hypothetical protein (25.5% evalue=2.E-23) YP_070028.1 similar to Yersinia pestis YPO1484 hypothetical protein (99.7% evalue=0) YP_070030.1 similar to Yersinia pestis YPO1485 conserved hypothetical protein (99.4% evalue=0); Vibrio cholerae VCA0110 hypothetical protein (30.3% evalue=4.E-67) YP_070031.1 similar to Yersinia pestis YPO1486 conserved hypothetical protein (100% evalue=0); Escherichia coli ECs0228 hypothetical protein (30% evalue=3.E-27) YP_070032.1 similar to Yersinia pestis YPO1487 conserved hypothetical protein (98.7% evalue=4.E-86); Salmonella typhimurium STM0280 outer membrane lipoprotein (28.3% evalue=2.E-11) YP_070033.1 similar to Yersinia pestis YPO1488 conserved hypothetical protein (99.3% evalue=2.E-81) YP_070034.1 similar to Yersinia pestis YPO1489 hypothetical protein (97.1% evalue=0); Escherichia coli ECs0217 hypothetical protein (30.7% evalue=2.E-50) YP_070035.1 similar to Yersinia pestis YPO1492 hypothetical protein (30.7% evalue=3.E-10) YP_070036.1 similar to Yersinia pestis YPO1491 ybiT; ABC transporter ATP-binding protein (99.6% evalue=0) YP_070037.1 similar to Yersinia pestis YPO1492 hypothetical protein (93.9% evalue=1.E-113) YP_070038.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_070039.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_070040.1 similar to Yersinia pestis YPO1496 heme-binding protein (99.7% evalue=0); Salmonella typhimurium STM0036 arylsulfatase regulatory protein (25.8% evalue=3.E-29) YP_070041.1 similar to Yersinia pestis YPO1497 ABC transporter ATP-binding protein (99% evalue=1.E-120); Bacillus subtilis BG13245 yknY; ABC transport system ATP-binding protein (47.2% evalue=6.E-53) YP_070042.1 similar to Yersinia pestis YPO1498 exported protein (98.3% evalue=0); A. aeolicus aq_294 protein (21.6% evalue=6.E-12) YP_070043.1 similar to Yersinia pestis YPO1499 membrane protein (98.6% evalue=0) YP_070044.1 similar to Yersinia pestis YPO1501 esterase (99.2% evalue=1.E-167); Escherichia coli JW2141 yeiG; esterase (73.5% evalue=1.E-124) YP_070045.1 similar to Yersinia pestis YPO1502 probable alcohol dehydrogenase / formaldehyde dehydrogenase (glutathione) (99.7% evalue=0); Pseudomonas aeruginosa PA3629 adhC; alcohol dehydrogenase class III (78.9% evalue=1.E-175) YP_070046.1 similar to Yersinia pestis YPO1503 LysR-family transcriptional regulatory protein (100% evalue=1.E-164); Pseudomonas aeruginosa PA1413 probable transcriptional regulator (53.7% evalue=1.E-79) YP_070047.1 similar to Yersinia pestis YPO1504 exported protein (100% evalue=0); Pseudomonas aeruginosa PA1412 hypothetical protein (45.8% evalue=8.E-79) YP_070048.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_070049.1 similar to Yersinia pestis YPO1506 yeiB; exported protein (99.4% evalue=0); Escherichia coli ECs3044 hypothetical protein (60.6% evalue=1.E-140) YP_070050.1 similar to Yersinia pestis YPO1507 mglB; galactose-binding protein (98.5% evalue=0); Salmonella typhimurium STM2190 mglB; D-galactose-binding periplasmic protein (85.4% evalue=1.E-163) YP_070051.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_070052.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_070053.1 similar to Yersinia pestis YPO1510 sanA; exported protein (100% evalue=1.E-138); Escherichia coli Z3399 sanA; vancomycin sensitivity (80% evalue=1.E-112) YP_070054.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_070055.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_070056.1 similar to Yersinia pestis YPO1513 yohK; membrane protein (99.5% evalue=1.E-126); Escherichia coli JW2130 yohK; Hypothetical protein (76.1% evalue=3.E-99) YP_070057.1 similar to Yersinia pestis YPO1514 yohJ; membrane protein (100% evalue=1.E-73); Salmonella typhimurium STM2181 yohJ; effector of murein hydrolase LrgA (68% evalue=2.E-45) YP_070058.1 similar to Yersinia pestis YPO1515 multidrug resistance protein (100% evalue=0); Salmonella typhimurium STM1516 ydeE; MFS family transport protein (40.8% evalue=2.E-76) YP_070059.1 similar to Yersinia pestis YPO1516 hypothetical protein (99.7% evalue=0) YP_070060.1 similar to Yersinia pestis YPO1517 sugar ABC transporter (100% evalue=0); Mesorhizobium loti mlr7288 ABC transporter binding protein (31.1% evalue=6.E-34) YP_070061.1 similar to Yersinia pestis YPO1518 membrane protein (99.4% evalue=3.E-99) YP_070062.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_070063.1 similar to Yersinia pestis YPO1523 conserved hypothetical protein (100% evalue=0); Escherichia coli JW2100 mrp; Mrp protein. (76.7% evalue=1.E-166) YP_070064.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_070065.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_070066.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_070067.1 similar to Yersinia pestis YPO1527 membrane protein (99.8% evalue=0); Salmonella typhimurium STM2119 yegH; inner membrane protein (72.1% evalue=0) YP_070068.1 similar to Yersinia pestis YPO1528 ferric iron reductase (98.8% evalue=1.E-154); Escherichia coli b4367 fhuF; ferric hydroxamate transport protein fhuF (38.6% evalue=1.E-41) YP_070069.1 similar to Yersinia pestis YPO1529 decarboxylase (99.2% evalue=0); Anabaena all0395 L-2,4-diaminobutyrate decarboxylase (42.8% evalue=1.E-106) YP_070070.1 similar to Yersinia pestis YPO1530 alcA; siderophore biosynthetic enzyme (100% evalue=0); Anabaena all0392 probable monooxygenase (46% evalue=1.E-110) YP_070071.1 similar to Yersinia pestis YPO1531 alcB; siderophore biosynthetic enzyme (100% evalue=1.E-112); Anabaena all0393 hypothetical protein (25.6% evalue=2.E-17) YP_070072.1 similar to Yersinia pestis YPO1538 siderophore biosynthetic enzyme (46.8% evalue=1.E-157) YP_070073.1 similar to Yersinia pestis YPO1533 iron-siderophore transport system, ATP-binding component (99.6% evalue=1.E-156); Agrobacterium tumefaciens Atu5316 fepC; ABC transporter, nucleotide binding/ATPase [iron-siderophore] (53.7% evalue=3.E-75) YP_070074.1 similar to Yersinia pestis YPO1534 iron-siderophore transport system, membrane permease component (100% evalue=0); Pseudomonas aeruginosa PA4161 fepG; ferric enterobactin transport system permease (37.9% evalue=7.E-45) YP_070075.1 similar to Yersinia pestis YPO1535 iron-siderophore transport system, transmembrane component (99.7% evalue=0); Escherichia coli Z0732 fepD; ferric enterobactin (enterochelin) transport (42.9% evalue=9.E-61) YP_070076.1 similar to Yersinia pestis YPO1536 iron-siderophore transport system, periplasmic binding protein (99.7% evalue=0); Agrobacterium tumefaciens AGR_pAT_447 DtxR/iron regulated lipoprotein precursor (34.1% evalue=1.E-43) YP_070077.1 similar to Yersinia pestis YPO1537 iron-siderophore receptor (99.7% evalue=0); Salmonella typhimurium STM1204 fhuE; outer membrane receptor for Fe(III)-coprogen, Fe(III)-ferrioxamine B and Fe(III)-rhodotrulic acid uptake (36.9% evalue=1.E-128) YP_070078.1 similar to Yersinia pestis YPO1538 siderophore biosynthetic enzyme (99.6% evalue=0) YP_070079.1 similar to Yersinia pestis YPO1539 galU; UTP-glucose-1-phosphate uridylyltransferase (100% evalue=1.E-168); Escherichia coli Z2012 galU; UTP--glucose-1-phosphate uridylyltransferase (73.4% evalue=1.E-122) YP_070080.1 similar to Yersinia pestis YPO1540 galF; UTP-glucose-1-phosphate uridylyltransferase (100% evalue=1.E-167); Escherichia coli ECs2846 Galf transferase (65.3% evalue=1.E-107) YP_070081.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_070082.1 similar to Yersinia pestis YPO3280 tnp; transposase for the IS1541 insertion element (100% evalue=6.E-89) YP_070083.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_070084.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_070085.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_070086.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_070087.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_070088.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_070089.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_070090.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_070091.1 similar to Yersinia pestis YPO1551 exported protein (100% evalue=1.E-157); Salmonella typhi STY2279 conserved hypothetical protein (65.3% evalue=6.E-99) YP_070093.1 similar to Yersinia pestis YPO1553 ribose transport system, permease (99.3% evalue=1.E-178); Mesorhizobium loti mlr7287 ABC transporter, permease (40.4% evalue=2.E-69) YP_070094.1 similar to Agrobacterium tumefaciens Atu2819 rbsA; ABC transporter, nucleotide binding/ATPase [ribose] (39.2% evalue=2.E-97); Agrobacterium tumefaciens AGR_C_5112 ABC transporter protein, ATP binding component (39.2% evalue=2.E-97) YP_070095.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_070096.1 similar to Yersinia pestis YPO1557 yeeF; Amino acid permease (99.7% evalue=0); Escherichia coli ECs2816 amino acid/amine transport protein (73.6% evalue=0) YP_070097.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_070098.1 similar to Yersinia pestis YPO1559 hypothetical protein (99.4% evalue=0); Ralstonia solanacearum RS03845 signal peptide protein (37.5% evalue=1.E-58) YP_070099.1 similar to Yersinia pestis YPO1560 conserved hypothetical protein (100% evalue=1.E-53); Escherichia coli Z3168 yeeX; alpha helix protein (84.1% evalue=3.E-44) YP_070100.1 similar to Yersinia pestis YPO3944 invasin (35.3% evalue=1.E-145) YP_070101.1 similar to Yersinia pestis YPO1563 transmembrane transporter (99.7% evalue=0); Salmonella typhi STY2520 transport protein (54.9% evalue=1.E-131) YP_070102.1 similar to Yersinia pestis YPO1564 membrane protein (97.8% evalue=2.E-77); Bacillus subtilis BG10978 yuxK, yugD; unknown (39% evalue=2.E-22) YP_070103.1 similar to Yersinia pestis YPO1565 oxidoreductase (100% evalue=1.E-135); Agrobacterium tumefaciens Atu4466 oxidoreductase (57.7% evalue=3.E-73) YP_070104.1 similar to Yersinia pestis YPO1566 2-hydroxyhepta-2,4-diene-1, 7-dioateisomerase / 5-carboxymethyl-2-oxo-hex-3-ene-1, 7-dioatedecarboxylase (99.6% evalue=1.E-164); Mesorhizobium loti mll4780 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (64.3% evalue=1.E-104) YP_070105.2 similar to Yersinia pestis YPO1567 racemase (100% evalue=0); Sinorhizobium meliloti SMb21113 enzyme similar to human rTSbeta protein (72.3% evalue=1.E-180) YP_070106.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_070107.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_070108.1 similar to Yersinia pestis YPO1571 yeeO; sugar transporter (100% evalue=0); Salmonella typhi STY2216 inner membrane protein (63.1% evalue=1.E-175) YP_070109.1 similar to Yersinia pestis YPO1572 sugar transporter (100% evalue=0); Escherichia coli ECs3031 transport protein (24% evalue=1.E-21) YP_070110.1 similar to Yersinia pestis YPO1573 polysaccharide deacetylase (99.6% evalue=0); Helicobacter pylori_J99jhp0295 (75.3% evalue=1.E-133) YP_070111.1 similar to Yersinia pestis YPO1574 exported protein (100% evalue=1.E-132) YP_070112.1 similar to Yersinia pestis YPO1575 conserved hypothetical protein (100% evalue=3.E-88); Salmonella typhimurium STM4192 cytoplasmic protein (87.1% evalue=1.E-82) YP_070113.1 similar to Yersinia pestis YPO3591 transposase for insertion sequence IS100 (100% evalue=0) YP_070114.1 similar to Yersinia pestis YPO3592 insertion sequence IS100, ATP-binding protein (100% evalue=1.E-142) YP_070116.1 similar to Yersinia pestis YPO1902 hypothetical protein (100% evalue=5.E-93); Salmonella typhi STY4526 hypothetical protein (34.6% evalue=9.E-24) YP_070117.1 similar to Yersinia pestis YPO1903 hypothetical protein (100% evalue=5.E-25) YP_070118.1 similar to Yersinia pestis YPO1905a hypothetical protein (100% evalue=1.E-62) YP_070119.1 similar to Yersinia pestis YPO1906 fyuA, psn; pesticin/yersiniabactin receptor protein (99.8% evalue=0); Ralstonia solanacearum RS04230 siderophore receptor protein (32.2% evalue=7.E-83) YP_070120.1 similar to Yersinia pestis YPO1907 ybtE, irp5; yersiniabactin siderophore biosynthetic protein (100% evalue=0); Bacillus subtilis BG11020 dhbE, entE; 2,3-dihydroxybenzoate-AMP ligase (enterobactin synthetase component E) (50.5% evalue=1.E-135) YP_070121.1 similar to Yersinia pestis YPO1908 ybtT, irp4; yersiniabactin biosynthetic protein YbtT (100% evalue=1.E-155); Bacillus subtilis BG10171 srfAD, comL, srfA4; surfactin synthetase subunit 4 (31.7% evalue=6.E-26) YP_070122.1 similar to Yersinia pestis YPO1909 ybtU, irp3; yersiniabactin biosynthetic protein YbtU (100% evalue=0); Ralstonia solanacearum RS04226 siderophore-like synthase (38.2% evalue=4.E-54) YP_070123.1 similar to Yersinia pestis YPO1910 irp1; yersiniabactin biosynthetic protein (99.9% evalue=0); Mesorhizobium loti mlr9053 polyketide synthase (38.7% evalue=1.E-167) YP_070124.1 similar to Yersinia pestis YPO1911 irp2; yersiniabactin biosynthetic protein (100% evalue=0) YP_070125.1 similar to Yersinia pestis YPO1912 ybtA; transcriptional regulator YbtA (100% evalue=0); Anabaena all2621 transcriptional regulator (34.3% evalue=2.E-18) YP_070126.1 similar to Yersinia pestis YPO1913 ybtP, irp6; lipoprotein inner membrane ABC-transporter (99.6% evalue=0); Ralstonia solanacearum RS04232 probable composite ATP-binding transmembrane ABC transporter protein (39% evalue=1.E-102) YP_070127.1 similar to Yersinia pestis YPO1914 ybtQ, irp7; inner membrane ABC-transporter YbtQ (100% evalue=0); Ralstonia solanacearum RS04232 probable composite ATP-binding transmembrane ABC transporter protein (34.3% evalue=2.E-81) YP_070129.1 catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin YP_070130.1 similar to Yersinia pestis YPO1576 GerR-family transcriptional regulatory protein (100% evalue=1.E-114); Escherichia coli ECs0418 transcription regulator (70.8% evalue=7.E-79) YP_070131.1 similar to Yersinia pestis YPO1577 C4-dicarboxylate transporter, large subunit (100% evalue=0); Agrobacterium tumefaciens AGR_L_3348 hypothetical 46.1 KD protein in PlsC 3'region (48.2% evalue=1.E-115) YP_070132.1 similar to Yersinia pestis YPO1578 C4-dicarboxylate transporter, small subunit (100% evalue=7.E-91); Sinorhizobium meliloti SMb21352 dctQ; C4-dicarboxylate small membrane transport protein (26.8% evalue=1.E-13) YP_070133.1 similar to Yersinia pestis YPO1579 C4-dicarboxylate transporter, periplasmic protein (99% evalue=0); Agrobacterium tumefaciens Atu3137 C4-dicarboxylate-binding protein (39% evalue=1.E-57) YP_070134.1 similar to Yersinia pestis YPO1580 phosphopantetheinyl transferase (99.1% evalue=1.E-139); Pseudomonas aeruginosa PA1165 hypothetical protein (36.9% evalue=4.E-23) YP_070135.1 similar to Yersinia pestis YPO1581 rafA; alpha-galactosidase (99.8% evalue=0); C. perfringens CPE0512 agaN; alpha-galactosidase (33.9% evalue=2.E-86) YP_070136.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_070137.1 similar to Sinorhizobium meliloti SMb20324 thuR; ThuR, regulatory protein for trehalosemaltose transport system (34.2% evalue=3.E-41); Brucella melitensis BMEII0946 laci-family transcription regulator (35.1% evalue=5.E-45) YP_070138.1 similar to Yersinia pestis YPO1732 conserved hypothetical protein (100% evalue=1.E-160); Escherichia coli Z3132 hypothetical protein (66% evalue=3.E-97) YP_070139.1 similar to Yersinia pestis YPO1733 conserved hypothetical protein (100% evalue=3.E-47); Mesorhizobium loti mlr3009 hypothetical protein (48.9% evalue=1.E-17) YP_070140.1 similar to Yersinia pestis YPO1734 conserved hypothetical protein (100% evalue=1.E-160); Pseudomonas aeruginosa PA4780 conserved hypothetical protein (67.7% evalue=1.E-105) YP_070141.1 similar to Yersinia pestis YPO1735 ABC transporter (ATP-binding protein) (100% evalue=0); Agrobacterium tumefaciens Atu1738 ABC transporter, nucleotide binding/ATPase (68% evalue=0) YP_070142.1 similar to Yersinia pestis YPO1737 AraC-family transcriptional regulatory protein (99.2% evalue=4.E-70) YP_070143.1 similar to Yersinia pestis YPO1738 conserved hypothetical protein (98.7% evalue=3.E-37); Escherichia coli JW1891 yecJ; Hypothetical protein (77.9% evalue=1.E-27) YP_070144.1 similar to Yersinia pestis YPO1739 membrane protein (98.6% evalue=9.E-35); Salmonella typhi STY1971 exported protein (54.7% evalue=3.E-18) YP_070145.1 similar to Yersinia pestis YPO1740 exported protein (95.7% evalue=9.E-43); Escherichia coli JW1814 hypothetical protein (50% evalue=1.E-09) YP_070146.1 similar to Yersinia pestis YPO1741 hypothetical protein (100% evalue=5.E-57) YP_070147.1 similar to Yersinia pestis YPO1742 hypothetical protein (99% evalue=3.E-52) YP_070148.1 similar to Yersinia pestis YPO3421 aroP; aromatic amino acid transport protein (77.7% evalue=0) YP_070149.1 catalyzes the transfer of palmitate to lipid A YP_070150.1 similar to Yersinia pestis YPO1745 conserved hypothetical protein (100% evalue=2.E-14); Salmonella typhi STY1968 conserved hypothetical protein (84.2% evalue=1.E-10) YP_070151.1 similar to Yersinia pestis YPO1746 cspC, msmB; cold shock protein (100% evalue=2.E-34); Escherichia coli b1823 cspC, msmB; cold shock-like protein cspC (98.5% evalue=5.E-34) YP_070152.1 similar to Yersinia pestis YPO1747 conserved hypothetical protein (100% evalue=1.E-145); Vibrio cholerae VC0710 conserved hypothetical protein (32.1% evalue=3.E-19) YP_070153.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_070154.1 similar to Yersinia pestis YPO2096 hypothetical phage protein (42.5% evalue=3.E-09) YP_070155.1 similar to Pseudomonas aeruginosa PA2177 probable sensor/response regulator hybrid (48.8% evalue=2.E-30) YP_070156.1 similar to Yersinia pestis YPO1753 fcuA; ferrichrome receptor protein (98.2% evalue=0); Caulobacter crescentus CC2928 TonB-dependent receptor (38.3% evalue=1.E-142) YP_070157.1 similar to Yersinia pestis YPO1754 yebN; membrane protein (100% evalue=1.E-103); Salmonella typhimurium STM1834 yebN; YebN family transport protein (69.5% evalue=5.E-72) YP_070158.1 similar to Yersinia pestis YPO1755 yobD; membrane protein (100% evalue=1.E-81); Salmonella typhi STY1962 membrane protein (61.1% evalue=1.E-49) YP_070159.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_070160.1 similar to Yersinia pestis YPO1757 manY, ptsP, pel; PTS system, mannose-specific IIC component (100% evalue=1.E-142); Escherichia coli JW1807 manY; Phosphotransferase system enzyme II, mannose-specific, factor II-P (87.7% evalue=1.E-126) YP_070161.1 similar to Yersinia pestis YPO1758 manX, ptsL, gptB; PTS system, mannose-specific IIAB component (99.6% evalue=1.E-180); Escherichia coli JW1806 manX; PTS system, mannose-specific II component (81.4% evalue=1.E-145) YP_070162.1 similar to Yersinia pestis YPO1759 yoaE; membrane protein (100% evalue=0); Salmonella typhi STY1958 membrane protein (73.5% evalue=0) YP_070163.1 similar to Yersinia pestis YPO1760 hpcR, hpaR; homoprotocatechuate degradative operon repressor (100% evalue=1.E-83); Salmonella typhimurium STM1100 hpaR; 4-hydroxyphenylacetate catabolism (70.5% evalue=7.E-52) YP_070164.1 similar to Salmonella typhi STY1134 hpaG; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase [includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (65.5% evalue=1.E-74) YP_070165.1 similar to Salmonella typhimurium STM1101 hpaG; bifunctional enzyme 2-hydroxyhepta-2,4-diene-1,7-dioatesomerase / 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioatedecarboxylase (76.5% evalue=1.E-93) YP_070166.1 similar to Yersinia pestis YPO1763 hpaE; 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase (95% evalue=0); Salmonella typhimurium STM1102 hpaE; 4-hydroxyphenylacetate catabolism (84% evalue=0) YP_070167.1 similar to Yersinia pestis YPO1764 hpaD; 3,4-dihydroxyphenylacetate 2,3-dioxygenase (99.6% evalue=1.E-167); Salmonella typhi STY1137 hpcB; 3,4-dihydroxyphenylacetate 2,3-dioxygenase (87.1% evalue=1.E-147) YP_070168.1 similar to Yersinia pestis YPO1765 hpaF; 5-carboxymethyl-2-hydroxymuconate delta-isomerase (100% evalue=2.E-72); Salmonella typhi STY1138 hpcD; 5-carboxymethyl-2-hydroxymuconate delta-isomerase (72.2% evalue=1.E-48) YP_070169.1 similar to Yersinia pestis YPO1766 hpaH, hpcG; 2-oxo-hept-3-ene-1,7-dioate hydratase (99.6% evalue=1.E-152); Salmonella typhi STY1139 hpcG; 2-oxo-hepta-3-ene-1,7-dioic acid hydratase (79.4% evalue=1.E-121) YP_070170.1 similar to Yersinia pestis YPO1767 hpaI, pcH; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (99.6% evalue=1.E-151); Salmonella typhi STY1140 hpcH, hpaI; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (73.7% evalue=1.E-105) YP_070171.1 similar to Yersinia pestis YPO1768 hpaX; 4-hydroxyphenylacetate permease (100% evalue=0); Salmonella typhi STY1141 hpaX; 4-hydroxyphenylacetate permease (76% evalue=0) YP_070172.1 similar to Yersinia pestis YPO1769 hpaB; 4-hydroxyphenylacetate 3-monooxygenase (100% evalue=0); Salmonella typhimurium STM1099 hpaB; 4-hydroxyphenylacetate catabolism (81.9% evalue=0) YP_070173.1 similar to Yersinia pestis YPO1770 hpaC; 4-hydroxyphenylacetate 3-monooxygenase coupling protein (100% evalue=1.E-94); Salmonella typhi STY1130 hpaC; 4-hydroxyphenylacetate 3-monooxygenase coupling protein (72.9% evalue=4.E-62) YP_070174.1 similar to Yersinia pestis YPO1771 sdaA; L-serine dehydratase (99.5% evalue=0); Escherichia coli JW1803 sdaA; L-serine dehydratase 1 (l-serine deaminase 1) (sdh 1) (l-sd1). (84.3% evalue=0) YP_070175.1 similar to Yersinia pestis YPO1772 MutT-family protein (99.4% evalue=1.E-111); Salmonella typhimurium STM1825 yeaB; NTP pyrophosphohydrolase (55.2% evalue=5.E-57) YP_070176.1 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine YP_070177.1 similar to Yersinia pestis YPO1774 conserved hypothetical protein (98.8% evalue=2.E-43); Salmonella typhimurium STM1823 yoaH; cytoplasmic protein (62.7% evalue=3.E-13) YP_070178.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_070179.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_070180.1 similar to Yersinia pestis YPO1777 conserved hypothetical protein (100% evalue=1.E-53); Escherichia coli JW1837 yebG; Hypothetical protein (ORF96) (55.7% evalue=2.E-23) YP_070181.1 similar to Yersinia pestis YPO1778 conserved hypothetical protein (100% evalue=8.E-54); Escherichia coli ECs3772 hypothetical protein (66.6% evalue=3.E-29) YP_070182.1 secreted protein; unknown function YP_070183.1 similar to Yersinia pestis YPO1780 ptrB, rlp; oligopeptidase B (100% evalue=0); Salmonella typhi STY2085 opdB; oligopeptidase (65% evalue=0) YP_070184.1 similar to Yersinia pestis YPO1781 pip; proline iminopeptidase (99.6% evalue=0); Mesorhizobium loti mlr7803 prolyl aminopeptidase (63.3% evalue=1.E-121) YP_070185.1 similar to Yersinia pestis YPO1782 holE; DNA polymerase III, theta subunit (100% evalue=2.E-37); Salmonella typhimurium STM1876 holE; DNA polymerase III, theta subunit (64.4% evalue=1.E-20) YP_070186.1 similar to Yersinia pestis YPO1783 ftnA, ftn, rsgA, gen-165; ferritin (99.4% evalue=4.E-93); Vibrio cholerae VC0078 ferritin (68.4% evalue=8.E-65) YP_070187.1 similar to Yersinia pestis YPO1784 copper resistance protein (100% evalue=2.E-68); Salmonella typhimurium STM1875 yobA; homolog of Cu resistance protein CopC (51.7% evalue=3.E-28) YP_070188.1 similar to Yersinia pestis YPO1785 copper resistance protein D (100% evalue=1.E-166); Escherichia coli ECs2550 resistance protein (40.5% evalue=9.E-53) YP_070189.1 similar to Yersinia pestis YPO1786 yebY; exported protein (99.1% evalue=2.E-61); Escherichia coli ECs2549 hypothetical protein (59.8% evalue=6.E-32) YP_070190.1 similar to Yersinia pestis YPO1788 acyl carrier protein (100% evalue=3.E-59); Salmonella typhimurium STM2011 cytoplasmic protein (73.1% evalue=2.E-43) YP_070191.1 similar to Yersinia pestis YPO1789 membrane protein (100% evalue=1.E-83); Salmonella typhi STY2214 hypothetical protein (81.1% evalue=1.E-54) YP_070192.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; Yersinia has 2 copies of flhB; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella YP_070193.1 membrane protein involved in the flagellar export apparatus YP_070194.1 similar to Yersinia pestis YPO1792 flhE; flagellar protein FlhE precursor (99.2% evalue=5.E-74); Escherichia coli JW1867 flhE; FlhE protein (45.1% evalue=3.E-23) YP_070195.1 similar to Yersinia pestis YPO3944 invasin (38.7% evalue=1.E-136) YP_070196.1 similar to Yersinia pestis YPO1796 flgN; flagella synthesis protein FlgN (99.3% evalue=1.E-77); Escherichia coli b1070 flgN; flagella synthesis protein flgN (44.2% evalue=5.E-22) YP_070197.1 regulates the flagellar specific sigma28 transcription factor YP_070198.1 required for the assembly of the flagellar basal body P-ring YP_070199.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_070200.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_070201.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_070202.1 the hook connects flagellar basal body to the flagellar filament YP_070203.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Yersinia contains two copies of this and other flagella genes YP_070204.1 makes up the distal portion of the flagellar basal body rod YP_070205.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_070206.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_070207.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_070208.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_070209.2 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes YP_070210.1 similar to Yersinia pestis YPO1810 transcriptional regulatory protein (99.6% evalue=0); Brucella melitensis BMEI0398 deoxyribonucleoside regulator / dihydroxyacetone kinase (41.5% evalue=6.E-67) YP_070211.1 similar to Yersinia pestis YPO1811 oxidoreductase (99.4% evalue=0); Mesorhizobium loti mll7289 probable oxidoreductase (48.6% evalue=0) YP_070212.1 similar to Yersinia pestis YPO1812 sugar transport system permease (97.7% evalue=0); Sinorhizobium meliloti SMb20315 sugar ABC transporter permease (59.7% evalue=1.E-104) YP_070213.1 similar to Yersinia pestis YPO1813 sugar-binding periplasmic protein (100% evalue=0); Sinorhizobium meliloti SMb20316 ABC transporter periplasmic sugar-binding protein (61.1% evalue=1.E-116) YP_070214.1 similar to Yersinia pestis YPO1814 sugar ABC transporter, ATP-binding protein (98.8% evalue=0); Sinorhizobium meliloti SMb20317 sugar ABC transporter ATP-binding protein (56.2% evalue=1.E-155) YP_070215.1 similar to Yersinia pestis YPO1815 sugar ABC transporter, permease (99.6% evalue=1.E-170); Sinorhizobium meliloti SMb20318 sugar ABC transporter permease (64.9% evalue=1.E-113) YP_070216.1 similar to Yersinia pestis YPO1816 sugar kinase (98.7% evalue=1.E-180); Escherichia coli JW1761 hypothetical protein (24.7% evalue=1.E-23) YP_070218.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_070219.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_070220.2 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_070221.1 similar to Yersinia pestis YPO1821 fliO, mopB; flagellar protein FliO (99.1% evalue=7.E-63); Salmonella typhimurium STM1978 fliO; flagellar biosynthesis (45.8% evalue=1.E-19) YP_070222.1 One of three proteins involved in switching the direction of the flagellar rotation YP_070223.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_070224.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_070225.1 similar to Yersinia pestis YPO1825 fliK; flagellar hook-length control protein FliK (99.3% evalue=0); Salmonella typhimurium STM1974 fliK; flagellar hook-length control protein (34.6% evalue=4.E-46) YP_070226.1 rod/hook and filament chaperone YP_070227.1 involved in type III protein export during flagellum assembly YP_070228.1 binds to and inhibits the function of flagella specific ATPase FliI YP_070229.1 One of three proteins involved in switching the direction of the flagellar rotation YP_070230.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_070231.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_070232.1 similar to Yersinia pestis YPO2123 phage minor tail protein (83.6% evalue=7.E-23) YP_070233.1 similar to Yersinia pestis YPO1832 hypothetical protein (99% evalue=2.E-53); Salmonella typhi STY1030 bacteriophage protein (70% evalue=3.E-18) YP_070234.1 similar to Yersinia pestis YPO1834 DNA-3-methyladenine glycosidase (99.5% evalue=1.E-110); M. pulmonis MYPU_0950 ogt; methylated-DNA--protein-cysteine methyltransferase (39.5% evalue=3.E-38) YP_070235.1 similar to Vibrio cholerae VCA0895 chemotactic transducer-related protein (35.8% evalue=1.E-153); Sinorhizobium meliloti SMc00339 cyaA; adenylate cyclase 1 protein (22.3% evalue=4.E-12) YP_070236.1 similar to Yersinia pestis YPO1837 AraC-family transcriptional regulatory protein (100% evalue=1.E-166); Salmonella typhimurium STM1082 bacterial regulatory protein, AraC family (28% evalue=1.E-19) YP_070237.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_070238.1 flagellin specific chaperone YP_070239.1 involved in flagellin assembly YP_070240.1 structural flagella protein YP_070241.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_070242.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_070243.1 catalyzes the formation of pyruvate from D-cysteine YP_070244.1 similar to Yersinia pestis YPO1846 fliY; cystine-binding periplasmic protein (100% evalue=1.E-147); Escherichia coli b1920 fliY; polar amino acid transport system substrate-binding protein (74% evalue=1.E-112) YP_070245.1 similar to Yersinia pestis YPO1847 yecS; amino-acid ABC transporter (permease) (99% evalue=1.E-119); Escherichia coli Z3006 yecS; transport system permease (former yecC) (80.9% evalue=2.E-97) YP_070246.1 similar to Yersinia pestis YPO1848 yecC; amino-acid ABC transporter (ATP-binding protein) (100% evalue=1.E-140); Salmonella typhimurium STM1951 yecC; ABC-type polar amino acid transport system, ATPase component (77.8% evalue=1.E-103) YP_070247.1 similar to Yersinia pestis YPO1849 conserved hypothetical protein (100% evalue=3.E-55) YP_070248.1 similar to Yersinia pestis YPO1850 hypothetical protein (99% evalue=4.E-62) YP_070249.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_070250.1 similar to Yersinia pestis YPO1853 putP; proline permease (100% evalue=0); Salmonella typhimurium STM1125 putP; SSS family, major sodium/proline symporter (81.2% evalue=0) YP_070251.1 similar to Yersinia pestis YPO1854 membrane protein (100% evalue=1.E-157); Escherichia coli ECs1263 cytochrome (76% evalue=1.E-121) YP_070252.1 similar to Yersinia pestis YPO1855 exported protein (98.9% evalue=0); Escherichia coli ECs1264 hypothetical protein (74.9% evalue=1.E-156) YP_070253.1 similar to Yersinia pestis YPO1856 conserved hypothetical protein (99.7% evalue=0); Escherichia coli b1019 ycdB; hypothetical 46.8 kD protein in putP-phoH intergenic region precursor (ORF1) (72.1% evalue=1.E-174) YP_070254.1 stationary phase that binds TrpR repressor YP_070255.1 similar to Yersinia pestis YPO1858 exported protein (100% evalue=0); H. influenzae HI0148 hypothetical protein HI0148 (46.4% evalue=3.E-96) YP_070256.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_070257.1 similar to Yersinia pestis YPO2905 ail; attachment invasion locus protein (45.3% evalue=5.E-38) YP_070258.1 similar to Yersinia pestis YPO1862 membrane protein (100% evalue=6.E-41) YP_070259.1 similar to Yersinia pestis YPO1863 ydgC, glpM; membrane protein (100% evalue=3.E-60); Salmonella typhimurium STM1476 ydgC; inner membrane protein (61.2% evalue=1.E-36) YP_070260.1 similar to Yersinia pestis YPO1864 conserved hypothetical protein (100% evalue=9.E-35); Escherichia coli b1915 yecF; hypothetical 8.2 kD protein in uvrY-sdiA intergenic region (60.8% evalue=5.E-19) YP_070261.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_070262.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_070263.1 similar to Yersinia pestis YPO1867 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (100% evalue=1.E-103); Salmonella typhimurium STM1945 pgsA; phosphatidylglycerophosphate synthetase (76.7% evalue=1.E-78) YP_070264.1 in E. coli K-12 this is in prophage P2 remnant YP_070265.1 similar to Salmonella typhi STY3702 regulator of late gene expression (52.9% evalue=1.E-107); Salmonella typhi STY2882 bacteriophage late gene regulator (52.9% evalue=1.E-107) YP_070266.1 similar to Salmonella typhi STY4602 phage tail protein (61% evalue=8.E-48); Salmonella typhi STY3701 phage tail protein (59% evalue=2.E-47) YP_070267.1 similar to Salmonella typhimurium STM2697 Fels-2 prophage:similar to orfG protein in phage 186 (34.2% evalue=1.E-100); Escherichia coli ECs2641 tail protein (35.5% evalue=1.E-101) YP_070268.1 similar to Salmonella typhi STY3699 hypothetical protein (66.6% evalue=4.E-07); Salmonella typhi STY2885 bacteriophage protein (66.6% evalue=4.E-07) YP_070269.1 similar to Salmonella typhi STY4605 phage tail protein (46.5% evalue=1.E-15); Ralstonia solanacearum RS03484 probable phage-related protein (50% evalue=1.E-15) YP_070270.1 similar to Salmonella typhi STY2887 probable major tail tube protein (59.4% evalue=1.E-54); Salmonella typhimurium STM2700 Fels-2 prophage: similar to genes in P2-like phages (60% evalue=4.E-55) YP_070271.1 similar to Salmonella typhi STY3696 probable major tail sheath protein (69.7% evalue=1.E-158); Salmonella typhi STY2888 bacteriophage major tail sheath protein (69.7% evalue=1.E-158) YP_070272.1 similar to Salmonella typhi STY3693 conserved hypothetical protein (39.1% evalue=2.E-08); Escherichia coli b2354 hypothetical protein (34.8% evalue=4.E-08) YP_070273.1 similar to Salmonella typhi STY4611 probable phage tail fibre protein (71.6% evalue=9.E-71); Salmonella typhi STY3691 probable variable tail fibre protein (70.5% evalue=7.E-70) YP_070274.1 similar to Salmonella typhi STY4612 phage tail protein (62.6% evalue=9.E-73); Salmonella typhi STY3690 phage tail protein (62.6% evalue=9.E-73) YP_070275.1 similar to Salmonella typhi STY3689 phage baseplate assembly protein (64.5% evalue=1.E-109); Salmonella typhimurium STM2708 Fels-2 prophage: similar to tail fiber protein (gpI) in phage P2 (64.2% evalue=1.E-108) YP_070276.1 similar to Salmonella typhi STY4614 phage baseplate assembly protein (63.8% evalue=3.E-33); Salmonella typhimurium STM2709 Fels-2 prophage: similar to gpJ, base plate of tail, in phage P2 (62.9% evalue=1.E-32) YP_070277.1 similar to Salmonella typhi STY4615 phage baseplate assembly protein (46.6% evalue=6.E-46); Salmonella typhi STY3687 phage baseplate assembly protein (44.6% evalue=4.E-46) YP_070278.1 similar to Salmonella typhi STY3686 phage tail protein (43.9% evalue=2.E-28); Salmonella typhimurium STM2711 Fels-2 prophage: similar to gpS for completion of tail, in phage P2 (44.8% evalue=2.E-28) YP_070279.1 similar to Salmonella typhi STY3685 phage tail protein (41.9% evalue=3.E-24); Ralstonia solanacearum RS03499 probable tail completion-like protein (49.6% evalue=5.E-31) YP_070280.1 similar to Salmonella typhi STY4618 regulatory protein (32.8% evalue=5.E-15); Salmonella typhimurium STM2714 Fels-2 prophage: similar to lysis protein (lysB) in phage P2 (34% evalue=2.E-14) YP_070281.1 similar to Salmonella typhi STY4620 nucD2; lysozyme (61.5% evalue=4.E-50); Salmonella typhimurium STM2715 Fels-2 prophage: probable prophage lysozyme (62.4% evalue=7.E-54) YP_070282.1 similar to Salmonella typhi STY3681 nucE; possible secretory protein (33.8% evalue=1.E-07) YP_070283.1 similar to Salmonella typhi STY4622 phage tail protein (64.1% evalue=1.E-19); Salmonella typhimurium STM2717 Fels-2 prophage: similar to gpX in phage P2 (64.1% evalue=2.E-19) YP_070284.1 similar to Salmonella typhi STY3679 capsid completion protein (44.6% evalue=4.E-29); Salmonella typhimurium STM2718 Fels-2 prophage: similar to gpQ in phage 186 (44% evalue=1.E-28) YP_070285.1 similar to Salmonella typhi STY4624 phage terminase (48.8% evalue=3.E-48); Ralstonia solanacearum RS03505 probable bacteriophage protein (52.4% evalue=1.E-57) YP_070286.1 Bacteriophage PhiD266; similar to Salmonella typhi STY4625 major capsid protein (58.4% evalue=1.E-113); Salmonella typhimurium STM2720 Fels-2 prophage: similar to gpN, major capsid, in phage P2 (56.9% evalue=1.E-113) YP_070287.1 similar to Salmonella typhi STY3676 capsid scaffolding protein (50.8% evalue=2.E-68); Salmonella typhimurium STM2721 Fels-2 prophage: similar to gpO, capsid scaffold, in phage P2 (50.8% evalue=3.E-67) YP_070288.1 similar to Salmonella typhi STY4627 probable terminase subunit (68.6% evalue=0); Salmonella typhimurium STM2722 Fels-2 prophage: similar to gpP, ATP charging, in phage P2 (68.6% evalue=0) YP_070289.1 similar to Salmonella typhi STY3675 terminase, ATPase subunit (38.3% evalue=7.E-40); Salmonella typhimurium STM2722 Fels-2 prophage: similar to gpP, ATP charging, in phage P2 (38.3% evalue=7.E-40) YP_070290.1 similar to Salmonella typhimurium STM2723 Fels-2 prophage: similar to gpQ, portal vector protein, in phage P2 (70.4% evalue=1.E-134); Ralstonia solanacearum RS03510 probable bacteriophage protein (64.8% evalue=1.E-133) YP_070292.1 similar to Salmonella typhi STY3668 possible endonuclease (34.4% evalue=1.E-63); Salmonella typhimurium STM2729 Fels-2 prophage: similar to retron in E coli (32.8% evalue=2.E-63) YP_070295.1 similar to Salmonella typhi STY3662 cII; regulatory protein cII (52.9% evalue=2.E-48); Salmonella typhimurium STM2736 Fels-2 prophage: similar to retron in E coli and to protein cII of phages (51.7% evalue=4.E-48) YP_070296.1 similar to Escherichia coli ECs2622 DNA-binding protein (48.2% evalue=2.E-09); Escherichia coli Z2970 coxT; regulator for prophage CP-933T (48.2% evalue=2.E-09) YP_070297.1 similar to Salmonella typhi STY4644 cI; phage repressor protein cI (35.4% evalue=2.E-22); Salmonella typhi STY3660 cI; repressor protein (34% evalue=1.E-24) YP_070298.1 similar to Sulfolobus tokodaii ST2108 hypothetical purine NTPase (21.9% evalue=6.E-07); Salmonella typhimurium STM2746 Excinuclease ATPase subunit (44.9% evalue=8.E-97) YP_070299.1 similar to Salmonella typhimurium STM2747 cytoplasmic protein (41.8% evalue=9.E-64) YP_070300.1 similar to Escherichia coli ECs2617 integrase (57.9% evalue=1.E-110); Escherichia coli Z2966 intT; integrase for prophage CP-933T (57.9% evalue=1.E-110) YP_070302.1 similar to Escherichia coli ECs2773 integrase (46.8% evalue=7.E-79); Escherichia coli Z3130 intU; integrase for prophage CP-933U (46.8% evalue=7.E-79) YP_070309.1 similar to Xylella fastidiosa XF1647 hypothetical protein (36.3% evalue=2.E-73) YP_070310.1 similar to Xylella fastidiosa XF1648 hypothetical protein (46% evalue=4.E-55) YP_070316.1 similar to Yersinia pestis YPO1233 prophage repressor protein (46.9% evalue=2.E-49); Escherichia coli ECs0274 repressor protein CI (36.2% evalue=4.E-30) YP_070319.1 similar to Anabaena all7134 hypothetical protein (26.8% evalue=2.E-08) YP_070321.1 Required for efficient pilin antigenic variation YP_070323.1 similar to Xylella fastidiosa XF0641 DNA methyltransferase (32% evalue=6.E-36); Caulobacter crescentus CC0378 modification methylase CcrMI (27.6% evalue=4.E-17) YP_070324.1 similar to Escherichia coli b2356 yfdM; hypothetical protein (61.3% evalue=1.E-28); Escherichia coli JW2352 yfdM; Hypothetical protein (61.3% evalue=1.E-28) YP_070325.1 similar to Mesorhizobium loti mlr8517 modification methylase (33.5% evalue=1.E-81) YP_070326.1 similar to Escherichia coli ECs1956 hypothetical protein (31.8% evalue=2.E-16); Escherichia coli Z2385 unknown protein encoded within prophage CP-933R (31.8% evalue=2.E-16) YP_070330.1 similar to Escherichia coli ECs2969 holin protein (65.2% evalue=5.E-22); Escherichia coli Z1468 lysis protein S of bacteriophage BP-933W (65.2% evalue=5.E-22) YP_070331.1 similar to Escherichia coli ECs0819 probable endolysin (lysis protein) (lysozyme) (56.5% evalue=2.E-46); Escherichia coli Z0960 lysozyme protein R of prophage CP-933K (56.5% evalue=2.E-46) YP_070334.1 similar to Yersinia pestis YPO3591 transposase for insertion sequence IS100 (100% evalue=0) YP_070335.1 similar to Yersinia pestis YPO3592 insertion sequence IS100, ATP-binding protein (100% evalue=1.E-142) YP_070336.1 similar to Escherichia coli ECs1219 small subunit terminase (39.4% evalue=1.E-47); Escherichia coli Z1475 terminase small subunit of bacteriophage BP-933W (39.4% evalue=1.E-47) YP_070337.1 similar to Escherichia coli ECs1220 terminase large subunit (70.5% evalue=0); Escherichia coli Z1476 partial terminase large subunit of bacteriophage BP-933W (70.5% evalue=0) YP_070338.1 similar to Escherichia coli ECs1221 portal protein (68.8% evalue=0); Escherichia coli Z1477 portal protein of bacteriophage BP-933W (68.8% evalue=0) YP_070339.1 similar to Escherichia coli ECs1222 hypothetical protein (41.8% evalue=3.E-68); Escherichia coli Z1478 unknown protein encoded by bacteriophage BP-933W (41.8% evalue=3.E-68) YP_070340.1 similar to Escherichia coli ECs1223 hypothetical protein (72.8% evalue=1.E-174); Escherichia coli Z1479 unknown protein encoded by bacteriophage BP-933W (72.8% evalue=1.E-174) YP_070341.1 similar to Escherichia coli ECs1224 hypothetical protein (40% evalue=1.E-16); Escherichia coli Z1480 unknown protein encoded by bacteriophage BP-933W (40% evalue=1.E-16) YP_070342.1 similar to Escherichia coli ECs1225 hypothetical protein (52.7% evalue=3.E-35); Escherichia coli Z1481 unknown protein encoded by bacteriophage BP-933W (52.7% evalue=3.E-35) YP_070343.1 similar to Escherichia coli ECs1226 hypothetical protein (37.8% evalue=1.E-30) YP_070344.1 similar to Escherichia coli ECs1227 hypothetical protein (58.7% evalue=6.E-69); Escherichia coli Z1482 unknown protein encoded by bacteriophage BP-933W (58.7% evalue=6.E-69) YP_070345.1 similar to Yersinia pestis YPO2133 hypothetical phage protein (85.9% evalue=9.E-62) YP_070346.1 similar to Yersinia pestis YPO2134 phage tail fiber assembly protein (86.3% evalue=5.E-67); Escherichia coli ECs1651 tail fiber assembly protein (31.8% evalue=6.E-10) YP_070347.1 similar to Yersinia pestis YPO1788 acyl carrier protein (70.3% evalue=9.E-40); Salmonella typhimurium STM2011 cytoplasmic protein (64.8% evalue=2.E-37) YP_070348.1 similar to Yersinia pestis YPO1789 membrane protein (76.6% evalue=2.E-62); Salmonella typhi STY2214 hypothetical protein (74% evalue=2.E-50) YP_070349.1 similar to Escherichia coli ECs1232 hypothetical protein (56.1% evalue=1.E-176); Escherichia coli Z1486 unknown protein encoded by bacteriophage BP-933W (56.1% evalue=1.E-176) YP_070350.1 similar to Escherichia coli ECs1233 tail tip fiber protein (47.9% evalue=1.E-101); Escherichia coli Z1487 unknown protein encoded by bacteriophage BP-933W (49.7% evalue=1.E-104) YP_070351.1 similar to Yersinia pestis YPO2132 hypothetical phage protein (26.9% evalue=1.E-07) YP_070352.1 similar to Escherichia coli ECs1237 hypothetical protein (53.8% evalue=5.E-31); Escherichia coli Z1490 unknown protein encoded by bacteriophage BP-933W (53.8% evalue=5.E-31) YP_070353.1 similar to Escherichia coli ECs1238 hypothetical protein (53% evalue=2.E-51); Escherichia coli Z1491 unknown protein encoded by bacteriophage BP-933W (53% evalue=2.E-51) YP_070354.1 similar to Escherichia coli ECs1239 hypothetical protein (58.4% evalue=1.E-33); Escherichia coli Z1492 unknown protein encoded by bacteriophage BP-933W (58.4% evalue=1.E-33) YP_070355.1 similar to Escherichia coli ECs1240 hypothetical protein (46.9% evalue=4.E-15); Escherichia coli Z1493 unknown protein encoded by bacteriophage BP-933W (46.9% evalue=4.E-15) YP_070356.1 similar to Escherichia coli ECs1241 hypothetical protein (28.4% evalue=6.E-40); Escherichia coli Z1494 unknown protein encoded by bacteriophage BP-933W (28.4% evalue=6.E-40) YP_070357.1 similar to Escherichia coli ECs1242 hypothetical protein (40.4% evalue=0) YP_070360.1 similar to Salmonella typhi STY3703 positive regulator of late gene transcription (66% evalue=6.E-16); Escherichia coli JW2067 ogrK; Ogr protein (62.5% evalue=6.E-16) YP_070361.1 similar to Salmonella typhi STY3702 regulator of late gene expression (65.1% evalue=1.E-137); Salmonella typhi STY2882 bacteriophage late gene regulator (65.1% evalue=1.E-137) YP_070362.1 similar to Salmonella typhi STY4602 phage tail protein (58.7% evalue=3.E-49); Salmonella typhimurium STM2696 Fels-2 prophage: similar to genes in phage phiCTX (58.7% evalue=2.E-49) YP_070363.1 similar to Salmonella typhi STY3700 hypothetical protein (30.2% evalue=1.E-114); Salmonella typhi STY2884 bacteriophage tail protein (30.2% evalue=1.E-114) YP_070364.1 similar to Salmonella typhi STY3699 hypothetical protein (64.1% evalue=1.E-08); Salmonella typhi STY2885 bacteriophage protein (64.1% evalue=1.E-08) YP_070365.1 similar to Salmonella typhi STY4605 phage tail protein (50% evalue=2.E-20); Salmonella typhimurium STM2699 Fels-2 prophage: similar to genes in P2-like phages (51.6% evalue=3.E-20) YP_070366.1 similar to Salmonella typhi STY2887 probable major tail tube protein (60.2% evalue=5.E-58); Salmonella typhimurium STM2700 Fels-2 prophage: similar to genes in P2-like phages (61.4% evalue=2.E-58) YP_070367.1 similar to Salmonella typhi STY3696 probable major tail sheath protein (78.9% evalue=1.E-180); Salmonella typhi STY2888 bacteriophage major tail sheath protein (78.9% evalue=1.E-180) YP_070368.1 similar to Salmonella typhi STY3693 conserved hypothetical protein (39.1% evalue=2.E-08); Escherichia coli b2354 hypothetical protein (34.8% evalue=4.E-08) YP_070369.1 similar to Salmonella typhi STY4611 probable phage tail fibre protein (73.3% evalue=2.E-72); Salmonella typhimurium STM2706 Fels-2 prophage: similar to tail fiber protein in phage P2 (73.8% evalue=9.E-73) YP_070370.1 similar to Salmonella typhi STY4612 phage tail protein (59.8% evalue=3.E-69); Salmonella typhi STY3690 phage tail protein (59.8% evalue=3.E-69) YP_070371.1 similar to Salmonella typhi STY4613 probable phage baseplate assembly protein (66.8% evalue=1.E-111); Salmonella typhi STY3689 phage baseplate assembly protein (67.5% evalue=1.E-113) YP_070372.1 similar to Yersinia pestis YPO1880 phage-related protein (95% evalue=2.E-38); Salmonella typhi STY3688 phage baseplate assembly protein (61.2% evalue=1.E-32) YP_070373.1 similar to Salmonella typhi STY4615 phage baseplate assembly protein (45.9% evalue=1.E-43); Salmonella typhi STY3687 phage baseplate assembly protein (46.4% evalue=6.E-44) YP_070374.1 downstream intergenic space has region identical to intergenic region downstream of IS285 in Yersinia pestis YP_070375.1 similar to Salmonella typhi STY3686 phage tail protein (52% evalue=1.E-38); Salmonella typhimurium STM2711 Fels-2 prophage: similar to gpS for completion of tail, in phage P2 (49.6% evalue=3.E-37) YP_070376.1 similar to Salmonella typhimurium STM2712 Fels-2 prophage: similar to gpR for completion of tail, in phage P2 (52.5% evalue=4.E-35); Ralstonia solanacearum RS03499 probable tail completion-like protein (53% evalue=1.E-35) YP_070377.1 similar to Salmonella typhi STY3684 regulatory protein (49.2% evalue=1.E-26); Salmonella typhimurium STM2714 Fels-2 prophage: similar to lysis protein (lysB) in phage P2 (47.7% evalue=4.E-25) YP_070378.1 similar to Agrobacterium tumefaciens Atu0462 endolysin (56.4% evalue=3.E-38); Agrobacterium tumefaciens AGR_C_820 gp19 (56.4% evalue=3.E-38) YP_070380.1 similar to Salmonella typhi STY4622 phage tail protein (70.1% evalue=2.E-24); Salmonella typhimurium STM2717 Fels-2 prophage: similar to gpX in phage P2 (70.1% evalue=2.E-24) YP_070381.1 similar to Salmonella typhi STY3679 capsid completion protein (46.8% evalue=3.E-31); Salmonella typhimurium STM2718 Fels-2 prophage: similar to gpQ in phage 186 (46.2% evalue=2.E-30) YP_070382.1 similar to Salmonella typhi STY3678 terminase, endonuclease subunit (38.9% evalue=6.E-37); Ralstonia solanacearum RS03505 probable bacteriophage protein (38.4% evalue=6.E-41) YP_070383.1 Bacteriophage PhiD5; similar to Salmonella typhi STY4625 major capsid protein (62.4% evalue=1.E-124); Salmonella typhi STY3677 major capsid protein (63% evalue=1.E-124) YP_070384.1 similar to Salmonella typhi STY4626 capsid protein (59.5% evalue=2.E-82); Salmonella typhi STY3676 capsid scaffolding protein (61.8% evalue=5.E-85) YP_070385.1 similar to Salmonella typhi STY4627 probable terminase subunit (63.8% evalue=0); Salmonella typhimurium STM2722 Fels-2 prophage: similar to gpP, ATP charging, in phage P2 (63.7% evalue=0) YP_070386.1 similar to Salmonella typhi STY4628 probable capsid portal protein (65.9% evalue=1.E-130); Salmonella typhimurium STM2723 Fels-2 prophage: similar to gpQ, portal vector protein, in phage P2 (67.2% evalue=1.E-132) YP_070388.1 similar to Salmonella typhi STY3668 possible endonuclease (35.8% evalue=1.E-129); Salmonella typhimurium STM2729 Fels-2 prophage: similar to retron in E coli (36.9% evalue=1.E-130) YP_070389.1 similar to Salmonella typhi STY4636 DNA adenine methylase (54% evalue=2.E-74); Salmonella typhi STY3667 DNA adenine methylase (55% evalue=5.E-76) YP_070390.1 similar to Salmonella typhi STY4637 exonuclease (54.4% evalue=3.E-45); C. muridarum TC0532 DNA polymerase III, epsilon subunit, (30.8% evalue=4.E-10) YP_070395.1 similar to Escherichia coli ECs2622 DNA-binding protein (64.1% evalue=7.E-17); Escherichia coli Z2970 coxT; regulator for prophage CP-933T (64.1% evalue=7.E-17) YP_070396.1 similar to Escherichia coli ECs2620 transcriptional regulator (41.5% evalue=1.E-12); Escherichia coli Z2969 unknown protein encoded by prophage CP-933T (41.5% evalue=1.E-12) YP_070397.1 similar to Saccharomyces cerevisiae YDL058W USO1, INT1; intracellular protein transport protein (21.3% evalue=1.E-11); A. thalianan At3g28770 T19N8.6; hypothetical protein (19.6% evalue=1.E-08) YP_070398.1 similar to Escherichia coli ECs2617 integrase (58.5% evalue=3.E-34); Escherichia coli Z2966 intT; integrase for prophage CP-933T (58.5% evalue=3.E-34) YP_070400.1 similar to Escherichia coli ECs2617 integrase (63.8% evalue=2.E-34); Escherichia coli Z2966 intT; integrase for prophage CP-933T (63.8% evalue=2.E-34) YP_070401.1 similar to Escherichia coli ECs2617 integrase (72.5% evalue=2.E-46); Escherichia coli Z2966 intT; integrase for prophage CP-933T (72.5% evalue=2.E-46) YP_070402.1 similar to Yersinia pestis YPO1870 hypothetical protein, 100% identical YP_070403.1 similar to Yersinia pestis YPO1871 hypothetical protein (64.5% evalue=8.E-20); M. musculus 14659 Glrp1, GRP-1; glutamine repeat protein 1 (64.1% evalue=3.E-10) YP_070404.1 similar to Yersinia pestis YPO1872 hypothetical protein, 99% identical YP_070405.1 similar to Yersinia pestis YPO1873 tnpA; transposase (98.1% evalue=0); Mycobacterium tuberculosis_CDC1551MT3534 IS1540, transposase (38.5% evalue=1.E-46) YP_070406.1 similar to Yersinia pestis YPO1874 conserved hypothetical protein (100% evalue=3.E-74) YP_070407.1 similar to Bacillus subtilis BG11115 yxaM, s14MR; similar to antibiotic resistance protein (26.6% evalue=4.E-18); B. burgdorferiBBI26 multidrug-efflux transporter (23.8% evalue=1.E-18) YP_070408.1 similar to Lactococcus lactis L130150 yjdA; hypothetical protein (27.3% evalue=3.E-16); Agrobacterium tumefaciens AGR_C_1920 biotin synthesis protein BioC (32.9% evalue=1.E-14) YP_070409.1 similar to Helicobacter pylori_J99jhp0993 (34.4% evalue=5.E-27); C. jejuni Cj0590 hypothetical protein Cj0590 (32.6% evalue=1.E-31) YP_070411.1 similar to Pasteurella multocida PM1158 hypothetical HI0095 (28.2% evalue=4.E-13); B. halodurans BH0821 unknown conserved protein (30.3% evalue=2.E-10) YP_070412.1 similar to Methanothermobacter thermautotrophicus MTH1335 diaminopimelate decarboxylase (25.5% evalue=2.E-24); A. fulgidus AF0800 lysA; diaminopimelate decarboxylase (28% evalue=2.E-24) YP_070413.1 similar to Bacillus subtilis BG13164 yjcK; similar to ribosomal-protein-alanine N-acetyltransferase (33.3% evalue=2.E-11); Brucella melitensis BMEI1452 ribosomal-protein-alanine acetyltransferase (30.2% evalue=7.E-10) YP_070414.1 similar to Yersinia pestis YPCD1.63 transposase (90.9% evalue=5.E-16); Vibrio cholerae VC0817 transposase, (77.5% evalue=2.E-21) YP_070415.1 similar to Yersinia pestis YPO1873 tnpA; transposase (99% evalue=0); Mycobacterium tuberculosis_CDC1551MT3534 IS1540, transposase (38.8% evalue=1.E-47) YP_070416.1 similar to Yersinia pestis YPO1876 hypothetical protein, 96% identical YP_070417.1 similar to Yersinia pestis YPO1877 hypothetical protein (99% evalue=5.E-57); Ralstonia solanacearum RS00212 hypothetical protein (52.5% evalue=2.E-17) YP_070418.1 similar to Yersinia pestis YPO1878 hypothetical protein, 100% identical YP_070419.1 similar to Yersinia pestis YPO1879 hypothetical protein (98.9% evalue=3.E-52) YP_070420.1 similar to Yersinia pestis YPO1880 phage-related protein (100% evalue=1.E-52); Salmonella typhi STY3688 phage baseplate assembly protein (71% evalue=2.E-26) YP_070421.1 similar to Yersinia pestis YPO1881 phage-related protein (98.3% evalue=5.E-63); Salmonella typhi STY3687 phage baseplate assembly protein (54.1% evalue=2.E-18) YP_070422.1 similar to Xylella fastidiosa XF1562 conserved hypothetical protein (52.9% evalue=5.E-17); Neisseria meningitidis NMB1118 conserved hypothetical protein (48.2% evalue=7.E-16) YP_070423.1 similar to Yersinia pestis YPO1882 conserved hypothetical protein (100% evalue=1.E-46); Sinorhizobium meliloti SMc04432 hypothetical protein (46.8% evalue=2.E-12) YP_070424.1 similar to Yersinia pestis YPO1583 transposase for the IS285 insertion element (91.9% evalue=2.E-57) YP_070425.1 similar to Yersinia pestis YPO1886 exported protein (100% evalue=1.E-103) YP_070426.1 similar to Yersinia pestis YPO1887 hypothetical protein (98.6% evalue=5.E-77) YP_070427.1 similar to Yersinia pestis YPO1890 GntR-family transcriptional regulatory protein (100% evalue=1.E-151); Caulobacter crescentus CC0445 transcriptional regulator, GntR family (41.2% evalue=2.E-48) YP_070428.1 similar to Yersinia pestis YPO1891 hypothetical protein, 100% identical. YP_070429.1 similar to Yersinia pestis YPO1892 oxidoreductase (99.7% evalue=0); Listeria monocytogenes lmo2800 similar to dehydrogenase (37.4% evalue=3.E-60) YP_070430.1 similar to Yersinia pestis YPO1893 exported solute-binding protein (99.5% evalue=0); Agrobacterium tumefaciens AGR_L_841 smoE; periplasmic sorbitol-binding protein (30.9% evalue=2.E-43) YP_070431.1 similar to Yersinia pestis YPO1894 binding-protein-dependent transport system, inner membrane component (100% evalue=1.E-160); Agrobacterium tumefaciens Atu2506 ABC transporter, membrane spanning protein [sugar] (40.6% evalue=1.E-59) YP_070432.1 similar to Yersinia pestis YPO1895 binding-protein-dependent transport system, inner membrane component (100% evalue=1.E-154); Pseudomonas aeruginosa PA2340 multiple sugar transport system permease (40.6% evalue=1.E-51) YP_070433.1 similar to Yersinia pestis YPO1896 binding-protein-dependent transport system, ATP-binding component (99.6% evalue=1.E-153); Vibrio cholerae VCA0946 maltose transport system ATP-binding protein (52.3% evalue=1.E-102) YP_070434.1 similar to Yersinia pestis YPO1918 probable pili assembly chaperone (100% evalue=1.E-139); Escherichia coli Z1534 chaperone (44.6% evalue=6.E-46) YP_070435.1 similar to Yersinia pestis YPO1919 exported protein (100% evalue=0); Escherichia coli Z1535 hypothetical protein (34.5% evalue=1.E-59) YP_070436.1 similar to Yersinia pestis YPO1920 probable fimbrial usher protein (99.7% evalue=0); Escherichia coli Z1536 usher protein (44.6% evalue=0) YP_070437.1 similar to Yersinia pestis YPO1921 probable pili assembly chaperone (88% evalue=1.E-112); Escherichia coli Z1537 chaperone (41.3% evalue=3.E-47) YP_070438.1 similar to Yersinia pestis YPO1922 fimbrial protein (100% evalue=7.E-94); Salmonella typhimurium STM0340 stbA; fimbriae; major subunit (46.3% evalue=8.E-34) YP_070439.1 similar to Pseudomonas aeruginosa PA3946 probable two-component sensor (27.6% evalue=1.E-120); Pseudomonas aeruginosa PA3044 probable two-component sensor (36.5% evalue=1.E-89) YP_070440.1 similar to Yersinia pestis YPO1925 two-component response regulator (100% evalue=1.E-112); Salmonella typhimurium STM0549 fimZ; fimbrial protein Z, transcriptional regulator (LuxR/UhpA family) (47.3% evalue=5.E-50) YP_070441.1 similar to Yersinia pestis YPO1926 4-hydroxybutyrate coenzyme A transferase (99.5% evalue=0); Salmonella typhimurium STM3118 acetyl-CoA hydrolase (76.1% evalue=0) YP_070442.1 similar to Yersinia pestis YPO1927 transcription regulatory protein (100% evalue=1.E-101); Salmonella typhimurium STM3119 monoamine oxidase (87.4% evalue=3.E-83) YP_070443.1 similar to Yersinia pestis YPO1928 citrate lyase beta chain (100% evalue=1.E-152); Salmonella typhimurium STM3120 transcriptional regulator, LysR family (72.3% evalue=1.E-109) YP_070444.1 similar to Yersinia pestis YPO1929 probable LysR-family transcriptional regulator (99.6% evalue=1.E-159); Salmonella typhimurium STM3121 transcriptional regulator, LysR family (78.6% evalue=1.E-123) YP_070445.1 similar to Yersinia pestis YPO1930 lipoprotein (98.7% evalue=1.E-89) YP_070446.1 similar to Yersinia pestis YPO1931 hypothetical protein (98.9% evalue=1.E-104) YP_070447.1 similar to Yersinia pestis YPO1932 sugar transporter (100% evalue=0); Pseudomonas aeruginosa PA2114 probable MFS transporter (55.7% evalue=1.E-131) YP_070448.1 similar to Yersinia pestis YPO1933 dicarboxylic acid hydrolase (99.6% evalue=1.E-171); Ralstonia solanacearum RS05190 probable hydrolase transmembrane protein (33.5% evalue=3.E-36) YP_070449.1 similar to Yersinia pestis YPO1934 LysR-family transcriptional regulatory protein (100% evalue=0); Sinorhizobium meliloti SMa0498 LysR-type regulator (26.4% evalue=7.E-20) YP_070450.1 Part of the NQR complex which has six subunits NqrA, NqrB, NqrC, NqrD, NqrE and NqrF. NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol YP_070451.1 similar to Yersinia pestis YPO1936 aminotransferase (100% evalue=0); Pseudomonas aeruginosa PA1654 probable aminotransferase (49.8% evalue=1.E-100) YP_070452.1 similar to Yersinia pestis YPO1937 ansP; L-asparagine permease (100% evalue=0); Salmonella typhimurium STM1584 ansP; APC family, L-asparagine transport protein (79.5% evalue=0) YP_070453.1 similar to Yersinia pestis YPO1938 probable deoR-family transcriptional regulatory protein (99.6% evalue=1.E-138); Escherichia coli JW2705 ygbI; Hypothetical transcriptional regulator (61.9% evalue=3.E-82) YP_070454.1 catalyzes the formation of glutamate from glutamine YP_070455.1 similar to Yersinia pestis YPO1940 membrane protein (100% evalue=0); Sinorhizobium meliloti SMa0185 possible transmembrane-transport protein (25.5% evalue=3.E-28) YP_070456.1 similar to Yersinia pestis YPO1941 membrane protein (99.8% evalue=0); Pasteurella multocida PM0453 hypothetical Yersinia pestis (64.2% evalue=0) YP_070457.1 similar to Yersinia pestis YPO1942 exported protein (100% evalue=1.E-100); Pasteurella multocida PM0452 hypothetical Yersinia pestis (81.5% evalue=1.E-84) YP_070458.1 similar to Yersinia pestis YPO1943 membrane protein (100% evalue=0); Pasteurella multocida PM0451 hypothetical Yersinia pestis (49.2% evalue=1.E-122) YP_070459.1 similar to Yersinia pestis YPO1944 membrane protein (100% evalue=0); Pasteurella multocida PM0450 hypothetical ABC transporter (67.5% evalue=1.E-162) YP_070460.1 similar to Yersinia pestis YPO1945 membrane protein (98.4% evalue=0); Pasteurella multocida PM0449 hypothetical Yersinia pestis (67.3% evalue=1.E-139) YP_070461.1 similar to Yersinia pestis YPO1946 ABC transporter, ATP-binding protein (99.5% evalue=1.E-132); Pasteurella multocida PM0448 hypothetical Yersinia pestis (77.6% evalue=3.E-94) YP_070462.1 similar to Yersinia pestis YPO1947 thioredoxin (100% evalue=3.E-91); Pasteurella multocida PM0447 resA; cytochrome c biogenesis protein, (38.7% evalue=3.E-30) YP_070463.1 similar to Yersinia pestis YPO1948 cytochrome (100% evalue=8.E-54); Pasteurella multocida PM0446 cytochrome c-553 homolog (40.2% evalue=5.E-14) YP_070464.1 with TehA confers resistance to tellurite YP_070465.1 similar to Yersinia pestis YPO1950 peptidase (99.5% evalue=0); Agrobacterium tumefaciens AGR_L_3328 hypothetical protein (32.7% evalue=3.E-45) YP_070466.1 in Yersinia this protein is important for biofilm formation and hemin adsorption YP_070467.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export YP_070468.2 predicted polysaccharide polymerase involved in biofilm formation; in Escherichia coli the related protein PgaC is required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; in Yersinia the HmsR protein is an inner membrane protein YP_070469.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption YP_070470.1 similar to Yersinia pestis YPO1955 acetyltransferase (99.6% evalue=0); Brucella melitensis BMEII0002 ribosomal-protein-serine acetyltransferase (44% evalue=5.E-52) YP_070471.1 similar to Yersinia pestis YPO1956 hypothetical protein (100% evalue=4.E-48) YP_070472.1 similar to Yersinia pestis YPO1957 phoH, psiH; phosphate starvation-inducible protein (100% evalue=1.E-144); Salmonella typhimurium STM1126 phoH; PhoB-dependent, ATP-binding pho regulon component (89.6% evalue=1.E-133) YP_070473.1 similar to Yersinia pestis YPO1958 chaA; calcium/proton antiporter (100% evalue=0); Salmonella typhimurium STM1771 chaA; CaCA family, sodium-calcium/proton antiporter (79.7% evalue=1.E-155) YP_070474.1 similar to Yersinia pestis YPO1959 narX, narR; nitrate/nitrite sensor protein (99.8% evalue=0); Escherichia coli ECs1727 nitrate/nitrite sensor protein NarX (47.8% evalue=1.E-150) YP_070475.1 similar to Yersinia pestis YPO1960 GntR-family regulatory protein (100% evalue=0); Escherichia coli JW1434 yjiR; Hypothetical protein (56.7% evalue=1.E-155) YP_070476.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_070477.1 similar to Yersinia pestis YPO1963 astA; arginine N-succinyltransferase (99.7% evalue=0); Escherichia coli ECs2453 arginine N-succinyltransferase (63.4% evalue=1.E-121) YP_070478.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_070479.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_070480.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_070481.1 similar to Yersinia pestis YPO1411 outer membrane porin C protein (59.8% evalue=1.E-116) YP_070482.1 similar to Yersinia pestis YPO1971 hutG; N-formylglutamate amidohydrolase (99.6% evalue=1.E-155); Pseudomonas aeruginosa PA5091 hutG; N-formylglutamate amidohydrolase (60.2% evalue=4.E-91) YP_070483.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_070484.1 similar to Yersinia pestis YPO1973 hutC; GntR-family transcriptional regulatory protein (99.2% evalue=1.E-143); Pseudomonas aeruginosa PA5105 hutC; histidine utilization repressor HutC (64% evalue=2.E-87) YP_070485.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_070486.1 similar to Yersinia pestis YPO1975 conserved hypothetical protein (98.9% evalue=1.E-110); Escherichia coli Z2774 hypothetical protein (37.4% evalue=1.E-23) YP_070487.1 similar to Yersinia pestis YPO1976 hypothetical protein (98% evalue=0) YP_070488.1 similar to Neisseria meningitidis NMB1916 3-oxoacyl-(acyl-carrier-protein) synthase III (30% evalue=8.E-38); Agrobacterium tumefaciens AGR_C_2178 3-oxoacyl-[acyl-carrier-protein] synthase III (31% evalue=1.E-37) YP_070489.1 similar to Yersinia pestis YPO1979 dehydrogenase (99.7% evalue=0) YP_070490.1 similar to Yersinia pestis YPO1980 conserved hypothetical protein (98.5% evalue=1.E-156); Xylella fastidiosa XF1361 conserved hypothetical protein (24.5% evalue=3.E-09) YP_070491.1 similar to Yersinia pestis YPO1981 coenzyme synthetase (99% evalue=0); Vibrio cholerae VC0924 capK protein, (33.3% evalue=2.E-10) YP_070492.1 similar to Yersinia pestis YPO1982 dehydrogenase (99.3% evalue=1.E-172); Pseudomonas aeruginosa PA4361 probable oxidoreductase (29.3% evalue=5.E-25) YP_070493.1 similar to Yersinia pestis YPO1983 glycosyl transferase (99.7% evalue=0); H. sapiens 7357 UGCG, GCS; UDP-glucose ceramide glucosyltransferase (21.7% evalue=3.E-11) YP_070494.1 similar to Yersinia pestis YPO1984 hypothetical protein (100% evalue=1.E-110) YP_070495.1 similar to Yersinia pestis YPO1985 glycosyl transferase (99.7% evalue=0) YP_070496.1 similar to Yersinia pestis YPO1986 exported protein (99.3% evalue=4.E-84) YP_070497.1 similar to Yersinia pestis YPO1987 hypothetical protein (99.6% evalue=0); Salmonella typhimurium STM2008 periplasmic protein (46% evalue=1.E-150) YP_070498.1 similar to Yersinia pestis YPO1989 exported protein (98.8% evalue=0); Salmonella typhimurium STM2007 TPR repeat protein (55.8% evalue=0) YP_070499.1 similar to Yersinia pestis YPO1990 membrane protein (99.4% evalue=0); Salmonella typhimurium STM2135 inner membrane protein (36.4% evalue=1.E-127) YP_070500.1 similar to Yersinia pestis YPO1991 sugar-phosphate isomerase (100% evalue=1.E-119); Salmonella typhimurium STM1933 ribose 5-phosphate isomerase (88.6% evalue=1.E-105) YP_070501.1 similar to Yersinia pestis YPO1992 conserved hypothetical protein (100% evalue=1.E-128); Escherichia coli Z1925 unknown protein encoded by prophage CP-933X (60% evalue=1.E-73) YP_070502.1 similar to Yersinia pestis YPO1993 dehydrogenase (99.5% evalue=1.E-125); Halobacterium VNG0115G yusZ1; oxidoreductase (32.1% evalue=6.E-24) YP_070503.1 similar to Yersinia pestis YPO1995 hypothetical protein (37.5% evalue=6.E-43) YP_070504.1 similar to Yersinia pestis YPO1995 hypothetical protein (100% evalue=1.E-177) YP_070505.1 similar to Yersinia pestis YPO1996 hypothetical protein (100% evalue=1.E-167) YP_070506.1 similar to Yersinia pestis YPO1997 exported protein (99.4% evalue=0) YP_070507.1 similar to Yersinia pestis YPO1998 exported protein (100% evalue=6.E-87); Sinorhizobium meliloti SMc01911 conserved hypothetical protein (57.7% evalue=1.E-40) YP_070508.1 similar to Yersinia pestis YPO1999 decarboxylase (99.2% evalue=4.E-73); Ralstonia solanacearum RS03072 probable 4-carboxymuconolactone decarboxylase (54.6% evalue=2.E-25) YP_070509.1 similar to Yersinia pestis YPO2000 two-component system sensor protein (99.5% evalue=0); Pseudomonas aeruginosa PA1438 probable two-component sensor (42.3% evalue=2.E-91) YP_070510.1 similar to Yersinia pestis YPO2001 copR; transcriptional activator (99.5% evalue=1.E-124); Pseudomonas aeruginosa PA1437 probable two-component response regulator (66% evalue=3.E-76) YP_070511.1 similar to Yersinia pestis YPO2002 conserved hypothetical protein (100% evalue=0); Escherichia coli ECs1909 hypothetical protein (36.9% evalue=8.E-50) YP_070512.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_070513.1 similar to Yersinia pestis YPO2004 membrane protein (99.5% evalue=1.E-132); Pasteurella multocida PM1936 unknown (53.1% evalue=6.E-66) YP_070514.1 similar to Yersinia pestis YPO2005 exported protein (98.9% evalue=1.E-166) YP_070515.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_070516.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_070517.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_070518.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_070519.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_070520.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_070521.2 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_070522.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_070523.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_070524.1 similar to Yersinia pestis YPO2019 membrane protein (100% evalue=2.E-73); Salmonella typhimurium STM1774 sirC; Regulation of invasion genes (55.8% evalue=4.E-32) YP_070525.1 similar to Yersinia pestis YPO2020 conserved hypothetical protein (100% evalue=1.E-152); Salmonella typhimurium STM1773 ychA; transcriptional regulator (63.9% evalue=5.E-98) YP_070526.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_070527.1 similar to Yersinia pestis YPO3280 tnp; transposase for the IS1541 insertion element (100% evalue=6.E-89) YP_070528.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_070529.1 similar to Yersinia pestis YPO3232 exported protein (45.7% evalue=3.E-63) YP_070530.1 similar to Yersinia pestis YPO2029 exported protein (99.7% evalue=0); Agrobacterium tumefaciens Atu4568 ABC transporter, substrate binding protein (23% evalue=2.E-13) YP_070531.1 similar to Yersinia pestis YPO2030 binding-protein-dependent transport system membrane protein (99.2% evalue=1.E-154); Agrobacterium tumefaciens Atu4571 ABC transporter, membrane spanning protein (34.9% evalue=5.E-39) YP_070532.1 similar to Yersinia pestis YPO2031 binding-protein-dependent transport system membrane protein (100% evalue=1.E-160); Agrobacterium tumefaciens Atu4570 ABC transporter, membrane spanning protein (27.2% evalue=1.E-26) YP_070533.1 similar to Mesorhizobium loti mll6255 ABC transporter ATP-binding component (44.5% evalue=2.E-68); Agrobacterium tumefaciens Atu4569 ABC transporter, nucleotide binding/ATPase (45.4% evalue=8.E-68) YP_070534.1 similar to Yersinia pestis YPO2035 hypothetical protein (99.6% evalue=1.E-160); Agrobacterium tumefaciens Atu6144 accF; agrocinopine phosphodiesterase (31.5% evalue=1.E-24) YP_070535.1 similar to Yersinia pestis YPO2036 transcriptional regulatory protein (100% evalue=0); Agrobacterium tumefaciens AGR_L_592 hypothetical 41.6 KD protein Y4FQ (31.3% evalue=2.E-43) YP_070536.1 similar to Yersinia pestis YPO2037 conserved hypothetical protein (100% evalue=1.E-142); Salmonella typhimurium STM1136 ycdX; Histidinol phosphatase and related hydrolases of the PHP family (77.5% evalue=1.E-112) YP_070537.1 similar to Yersinia pestis YPO2038 conserved hypothetical protein (100% evalue=1.E-106); Escherichia coli JW1018 ycdY; Hypothetical protein (65.9% evalue=8.E-68) YP_070538.1 similar to Yersinia pestis YPO2039 lipoprotein (100% evalue=1.E-102); Salmonella typhimurium STM1164 yceB; outer membrane lipoprotein (65.7% evalue=7.E-66) YP_070539.1 Confers resistance to norfloxacin and enoxacin YP_070540.1 similar to Yersinia pestis YPO2041 rimJ; ribosomal-protein-alanine acetyltransferase (100% evalue=1.E-114); Salmonella typhimurium STM1167 rimJ; acetylation of N-terminal alanine of 30S ribosomal subunit protein S5 (77.3% evalue=2.E-88) YP_070541.1 similar to Yersinia pestis YPO2042 oxidoreductase (100% evalue=1.E-128); Escherichia coli JW1054 yceH; Hypothetical protein (60.8% evalue=2.E-69) YP_070542.1 similar to Yersinia pestis YPO2042 oxidoreductase (99.6% evalue=1.E-173); Escherichia coli b1068 mviM; virulence factor mviM homolog (63% evalue=1.E-108) YP_070543.1 similar to Yersinia pestis YPO2043 mviN; membrane protein (99.8% evalue=0); Escherichia coli JW1056 mviN; Virulence factor MviN homolog (85.2% evalue=0) YP_070544.1 similar to Yersinia pestis YPO3720 shlB, hpmB; hemolysin activator protein (41.3% evalue=1.E-129) YP_070545.1 similar to Yersinia pestis YPO3721 hemolysin (30.4% evalue=0) YP_070546.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_070547.1 similar to Yersinia pestis YPO2047 conserved hypothetical protein (99.4% evalue=1.E-111); Escherichia coli b1875 yecM; hypothetical 21.4 kD protein in cutC-argS intergenic region (58.2% evalue=2.E-58) YP_070548.1 similar to Yersinia pestis YPO2048 cutC; copper homeostasis protein (99.6% evalue=1.E-143); Escherichia coli JW1863 cutC; Copper homeostasis protein (56.5% evalue=3.E-78) YP_070549.1 similar to Yersinia pestis YPO2049 conserved hypothetical protein (99.3% evalue=0); Salmonella typhi STY2114 conserved hypothetical protein (78.9% evalue=1.E-151) YP_070550.1 similar to Yersinia pestis YPO2050 conserved hypothetical protein (100% evalue=1.E-152); Salmonella typhimurium STM1905 yecO; SAM-dependent methyltransferases (85.1% evalue=1.E-118) YP_070551.1 similar to Yersinia pestis YPO2051 membrane protein (100% evalue=5.E-71); Escherichia coli ECs2579 hypothetical protein (70.5% evalue=1.E-53) YP_070552.1 similar to Yersinia pestis YPO2052 conserved hypothetical protein (99.2% evalue=1.E-163); Salmonella typhi STY2111 yecE; conserved hypothetical protein (62.3% evalue=1.E-100) YP_070553.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_070554.1 converts dATP to dAMP and pyrophosphate YP_070555.1 similar to Yersinia pestis YPO2055 conserved hypothetical protein (100% evalue=1.E-137); Salmonella typhimurium STM1899 yebC; cytoplasmic protein (85% evalue=1.E-120) YP_070556.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_070557.2 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_070558.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_070559.1 involved in transport of zinc(II) with ZnuA and C YP_070560.2 involved in transport of zinc(II) with ZnuA and C YP_070561.1 involved in transport of zinc(II) with ZnuA and C YP_070562.1 similar to Yersinia pestis YPO2062 M23/M37 peptidase-family protein (100% evalue=0); Salmonella typhimurium STM1890 yebA; Peptidase (74.7% evalue=0) YP_070563.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_070564.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_070565.1 Represses the expression of the zwf, eda, glp and gap YP_070566.2 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_070567.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_070568.1 similar to Yersinia pestis YPO2068 integral membrane protein (98% evalue=2.E-81); Salmonella typhi STY1585 conserved membrane protein (66.6% evalue=2.E-35) YP_070569.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_070570.1 similar to Yersinia pestis YPO2070 conserved hypothetical protein (100% evalue=5.E-61); Escherichia coli ECs2518 hypothetical protein (72.8% evalue=5.E-43) YP_070571.1 similar to Yersinia pestis YPO2071 DEAD box family helicase (99.6% evalue=0); Escherichia coli ECs2517 enzyme (79.9% evalue=0) YP_070572.1 similar to Yersinia pestis YPO2072 conserved hypothetical protein (99.5% evalue=1.E-130); Salmonella typhimurium STM1820 yeaZ; molecular chaperone (74.6% evalue=3.E-95) YP_070573.1 similar to Yersinia pestis YPO2073 lipoprotein (100% evalue=1.E-115); Escherichia coli ECs2515 outer membrane protein (63.7% evalue=5.E-63) YP_070574.1 Activates fatty acids by binding to coenzyme A YP_070575.1 similar to Yersinia pestis YPO2075 rnd; ribonuclease D (99.7% evalue=0); Escherichia coli JW1793 rnd; ribonuclease D (67.8% evalue=1.E-148) YP_070576.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_070577.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_070578.1 blocks the formation of polar Z-ring septums YP_070579.1 similar to Yersinia pestis YPO2080 conserved hypothetical protein (100% evalue=5.E-46); Escherichia coli Z1941 ycgL; orf, hypothetical protein (71.7% evalue=5.E-31) YP_070580.1 similar to Yersinia pestis YPO2081 lipoprotein (99.7% evalue=0); Vibrio cholerae VC1956 lytic murein transglycosylase, (48.6% evalue=4.E-83) YP_070581.1 similar to Yersinia pestis YPO2082 fumarylacetoacetate hydrolase family protein (100% evalue=1.E-122); Salmonella typhimurium STM1812 ycgM; Fumarylacetoacetate (FAA) hydrolase family (72.6% evalue=6.E-92) YP_070582.1 similar to Yersinia pestis YPO2083 conserved hypothetical protein (100% evalue=1.E-88); Escherichia coli b1181 ycgN; hypothetical 18.6 kD protein in minC-shea intergenic region (85.1% evalue=2.E-75) YP_070583.1 similar to Yersinia pestis YPO2137 conserved hypothetical phage protein (99.7% evalue=0); Staphylococcus aureus_N315 SA2061 hypothetical protein (21.4% evalue=7.E-09) YP_070584.1 similar to Yersinia pestis YPO2138 aminotransferase (98.7% evalue=0); Salmonella typhimurium STM2543 nifS; aminotransferase class-V (50.7% evalue=1.E-101) YP_070585.1 similar to Yersinia pestis YPO2139 hypothetical phage protein (100% evalue=1.E-136) YP_070586.1 similar to Yersinia pestis YPO2140 hypothetical phage protein (100% evalue=1.E-59) YP_070587.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_070588.1 involved in regulation of intracellular pH under alkaline conditions YP_070589.1 Multifunctional regulator of fatty acid metabolism YP_070590.1 similar to Yersinia pestis YPO2145 conserved hypothetical protein (99.8% evalue=0); Escherichia coli JW1177 ycgB; Hypothetical protein (84.8% evalue=0) YP_070591.1 catalyzes the oxidative deamination of D-amino acids YP_070592.1 similar to Yersinia pestis YPO2148 multidrug resistance protein (97.6% evalue=0); Vibrio cholerae VC0069 multidrug resistance protein, (36.3% evalue=6.E-59) YP_070593.1 similar to Yersinia pestis YPO2149 conserved hypothetical protein (99.6% evalue=1.E-170); Salmonella typhimurium STM0951 cytoplasmic protein (68.5% evalue=1.E-118) YP_070594.1 similar to Yersinia pestis YPO2150 LysR-family transcriptional regulatory protein (100% evalue=1.E-169); Salmonella typhimurium STM0952 transcriptional regulator, lysR family (57% evalue=3.E-94) YP_070595.1 similar to Yersinia pestis YPO2151 membrane protein (99.7% evalue=0); Mesorhizobium loti mll2462 hypothetical protein (52.4% evalue=1.E-101) YP_070596.1 similar to Yersinia pestis YPO2152 conserved hypothetical protein (100% evalue=0); Escherichia coli JW1773 yeaH; Hypothetical protein (86.6% evalue=0) YP_070597.1 similar to Yersinia pestis YPO2153 conserved hypothetical protein (100% evalue=0); Salmonella typhimurium STM1285 yeaG; Ser protein kinase (94.8% evalue=0) YP_070598.1 similar to Yersinia pestis YPO2155 exported protein (99.6% evalue=1.E-151); Salmonella typhimurium STM1286 mipA; scaffolding protein for murein-synthesizing holoenzyme (57.8% evalue=2.E-81) YP_070599.1 similar to Yersinia pestis YPO2156 conserved hypothetical protein (100% evalue=1.E-170); Salmonella typhimurium STM1289 yeaD; enzymes related to aldose 1-epimerase (58.4% evalue=1.E-102) YP_070600.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate YP_070601.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_070602.1 similar to Yersinia pestis YPO2159 conserved hypothetical protein (100% evalue=1.E-45); Salmonella typhi STY1823 conserved hypothetical protein (73.4% evalue=6.E-29) YP_070603.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_070604.1 converts asparagine to aspartate and ammonia YP_070605.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_070606.1 similar to Yersinia pestis YPO2163 nitroreductase (100% evalue=1.E-103); Salmonella typhimurium STM1296 ydjA; oxidoreductase (66.1% evalue=2.E-65) YP_070607.1 catalyzes the formation of selenophosphate from selenide and ATP YP_070608.1 decatenates replicating daughter chromosomes YP_070609.1 similar to Yersinia pestis YPO2166 exported protein (100% evalue=6.E-52); Salmonella typhi STY1814 exported protein (45.2% evalue=3.E-18) YP_070610.1 similar to Yersinia pestis YPO2167 nudG; pyrophosphohydrolase (100% evalue=1.E-70); Escherichia coli JW1748 hypothetical protein (65.3% evalue=4.E-40) YP_070611.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_070612.1 similar to Yersinia pestis YPO3682 lysR-family transcriptional regulatory protein (25.5% evalue=2.E-11) YP_070613.1 similar to Yersinia pestis YPO1583 transposase for the IS285 insertion element (100% evalue=0) YP_070614.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_070615.1 similar to Yersinia pestis YPO2172 conserved hypothetical protein (98.7% evalue=2.E-92); Escherichia coli Z2009 ychJ; orf, hypothetical protein (53.2% evalue=2.E-43) YP_070616.1 similar to Yersinia pestis YPO2173 probable response regulator (99.7% evalue=0); Escherichia coli Z2011 hnr; Hnr protein (64.6% evalue=1.E-126) YP_070617.1 similar to Yersinia pestis YPO2174 nucleotide sugar dehydrogenase (100% evalue=0); Mesorhizobium loti mlr5265 UDP-glucose dehydrogenase (66.7% evalue=1.E-169) YP_070618.1 similar to Yersinia pestis YPO2175 hns, hnsA, drdX, osmZ, bglY, msyA, cur, pilG, topS; DNA-binding protein Hns (97.7% evalue=7.E-67); Salmonella typhi STY1299 hns; DNA-binding protein (histone-like protein Hlp-II) (86.6% evalue=6.E-61) YP_070619.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_070620.1 similar to Yersinia pestis YPO2180 adhE, ana; aldehyde-alcohol dehydrogenase (100% evalue=0); Escherichia coli JW1228 adhE; alcohol dehydrogenase / acetaldehyde dehydrogenase (90.6% evalue=0) YP_070621.1 similar to Yersinia pestis YPO2181 membrane protein (99% evalue=1.E-114); Salmonella typhimurium STM1748 ychE; integral membrane proteins of the MarC family (84.4% evalue=9.E-96) YP_070622.1 similar to Yersinia pestis YPO2182 oppA; periplasmic oligopeptide-binding protein precursor (100% evalue=0); Salmonella typhimurium STM1746 oppA; ABC superfamily (periplasm), oligopeptide transport protein with chaperone properties (78.4% evalue=0) YP_070623.1 similar to Yersinia pestis YPO2183 oppB; oligopeptide transport system permease (100% evalue=1.E-171); Escherichia coli ECs1744 oligopeptide transport permease (92.4% evalue=1.E-158) YP_070624.1 similar to Yersinia pestis YPO2184 oppC; oligopeptide transport system permease (100% evalue=1.E-166); Escherichia coli ECs1745 oligopeptide transport system permease OppC (92.3% evalue=1.E-156) YP_070625.1 similar to Yersinia pestis YPO2185 oppD; oligopeptide transport ATP-binding protein (100% evalue=0); Escherichia coli ECs1746 oligopeptide ABC transport system ATP-binding protein OppD (87.6% evalue=1.E-162) YP_070626.1 similar to Yersinia pestis YPO2186 oppF; oligopeptide transport ATP-binding protein (100% evalue=0); Escherichia coli ECs1747 oligopeptide ABC transport system ATP-binding protein OppF (90.7% evalue=1.E-175) YP_070627.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_070628.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_070629.1 similar to Yersinia pestis YPO2189 hypothetical protein, 100% identical YP_070630.1 similar to Yersinia pestis YPO2905 ail; attachment invasion locus protein (44.9% evalue=9.E-39) YP_070631.1 similar to Yersinia pestis YPO2191 hypothetical protein (100% evalue=8.E-47) YP_070632.1 similar to Mesorhizobium loti msl7161 hypothetical protein (53.4% evalue=2.E-13); C. jejuni Cj1164c hypothetical protein Cj1164c (49.4% evalue=9.E-16) YP_070633.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_070634.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_070635.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_070636.1 Involved in cell division; probably involved in intracellular septation YP_070637.1 similar to Vibrio cholerae VCA0103 sulfate permease family protein (57.4% evalue=1.E-180); Pseudomonas aeruginosa PA1647 probable sulfate transporter (42.6% evalue=1.E-114) YP_070638.1 similar to Yersinia pestis YPO2199 membrane protein (100% evalue=1.E-131); Salmonella typhimurium STM1734 yciC; inner membrane protein (50.6% evalue=1.E-68) YP_070639.1 similar to Yersinia pestis YPO2200 hypothetical protein, 100% identical YP_070640.1 receptor for colicin S4 YP_070641.1 similar to Yersinia pestis YPO2202 lipoprotein (100% evalue=1.E-51) YP_070642.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_070643.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_070644.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_070645.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_070646.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_070647.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_070649.1 similar to Yersinia pestis YPO2210 hypothetical protein, 98% identical. YP_070650.1 similar to Yersinia pestis YPO2211 trpH; conserved hypothetical protein (100% evalue=1.E-173); Escherichia coli ECs1838 enzymes (72.9% evalue=1.E-113) YP_070651.1 similar to Yersinia pestis YPO2212 conserved hypothetical protein (100% evalue=1.E-117); Salmonella typhi STY1330 conserved hypothetical protein (82.4% evalue=1.E-97) YP_070652.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_070653.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_070654.1 similar to Yersinia pestis YPO2215 short chain dehydrogenase (100% evalue=1.E-140); Salmonella typhi STY1333 hypothetical oxidoreductase (75% evalue=1.E-105) YP_070655.1 SohB; periplasmic protein; member of the peptidase S49 family YP_070656.1 similar to Yersinia pestis YPO2217 conserved hypothetical protein (100% evalue=4.E-43); Escherichia coli ECs1845 hypothetical protein (68.6% evalue=5.E-27) YP_070657.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_070658.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_070659.1 similar to Yersinia pestis YPO2220 hypothetical protein (99.2% evalue=1.E-165) YP_070660.1 Catalyzes the conversion of citrate to isocitrate YP_070661.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_070662.1 similar to Yersinia pestis YPO2223 pgpB; phosphatidylglycerophosphatase B (100% evalue=1.E-149); Salmonella typhimurium STM1710 pgpB; phosphatidylglycerophosphatase B (58.1% evalue=4.E-86) YP_070663.1 similar to Yersinia pestis YPO2224 membrane protein (99% evalue=3.E-50); Escherichia coli JW1271 yciS, yciM; Hypothetical protein (67.6% evalue=9.E-34) YP_070664.1 similar to Yersinia pestis YPO2225 conserved hypothetical protein (99.7% evalue=0); Salmonella typhimurium STM1708 yciM; N-acetylglucosaminyl transferase (78.9% evalue=0) YP_070665.1 similar to Yersinia pestis YPO2226 hypothetical protein (100% evalue=1.E-48) YP_070666.1 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_070667.1 involved in start site selection during the initiation of translation YP_070668.1 similar to Yersinia pestis YPO2229 osmB; osmotically inducible lipoprotein B precursor (100% evalue=9.E-33); Salmonella typhi STY1346 osmB; osmotically inducible lipoprotein B precursor (79.1% evalue=2.E-25) YP_070669.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_070670.1 similar to Yersinia pestis YPO2231 hypothetical protein (100% evalue=6.E-42); Caulobacter crescentus CC0773 hypothetical protein (39.5% evalue=2.E-12) YP_070671.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_070672.1 similar to Yersinia pestis YPO2233 conserved hypothetical protein (99% evalue=2.E-57); Escherichia coli JW0591 ybdD; Hypothetical protein (ORF2) (54% evalue=2.E-09) YP_070673.1 similar to Yersinia pestis YPO2234 cstA; carbon starvation protein A (99.7% evalue=0); Ralstonia solanacearum RS01844 cstA, RSc0022; probable carbon starvation A transmembrane protein (64.4% evalue=0) YP_070674.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_070675.1 similar to Yersinia pestis YPO2237 integral membrane protein (99.7% evalue=0); Ralstonia solanacearum RS01194 probable permease transmembrane protein (60.2% evalue=1.E-155) YP_070676.1 similar to Yersinia pestis YPO2238 conserved hypothetical protein (99.3% evalue=0); Brucella melitensis BMEII1094 4-hydroxybutyrate dehydrogenase (48.8% evalue=2.E-80) YP_070677.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines YP_070678.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_070679.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_070680.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_070681.1 similar to Yersinia pestis YPO2243 AraC-family transcriptional regulatory protein (99.6% evalue=1.E-170) YP_070682.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_070683.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_070684.1 similar to Yersinia pestis YPO2246 membrane protein (100% evalue=1.E-102); Escherichia coli JW1619 ydgQ; Hypothetical protein (88.5% evalue=7.E-93) YP_070685.1 similar to Yersinia pestis YPO2247 membrane protein (100% evalue=3.E-80); Salmonella typhimurium STM1460 ydgK; inner membrane protein (56.2% evalue=2.E-37) YP_070686.1 similar to Xylella fastidiosa XF2397 toxin secretion ABC transporter ATP-binding protein (44.7% evalue=1.E-155); Vibrio cholerae VC1448 RTX toxin transporter (49.6% evalue=0) YP_070687.1 similar to Xylella fastidiosa XF2398 hemolysin secretion protein D (39.2% evalue=2.E-80); Vibrio cholerae VC1447 RTX toxin transporter (39.3% evalue=2.E-85) YP_070688.1 similar to Yersinia pestis YPO2252 toxin transport protein (99.4% evalue=0); Vibrio cholerae VC1446 toxin secretion transporter, (52.2% evalue=0) YP_070689.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_070690.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_070691.1 similar to Yersinia pestis YPO2255 araF; L-arabinose-binding periplasmic protein precursor (99.6% evalue=0); Escherichia coli b1901 araF; L-arabinose transport system substrate-binding protein (87.4% evalue=1.E-163) YP_070692.2 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_070693.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_070694.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_070695.1 similar to Yersinia pestis YPO2259 oxidoreductase (100% evalue=0); Salmonella typhi STY1660 oxidoreductase (72.5% evalue=1.E-147) YP_070696.1 similar to Yersinia pestis YPO2260 membrane protein (99.4% evalue=0); Escherichia coli Z3675 yfeH; cytochrome oxidase (65% evalue=1.E-112) YP_070697.1 catalyzes the formation of inosine from adenosine YP_070699.1 similar to Pasteurella multocida PM0373 unknown (54.9% evalue=4.E-86); Listeria monocytogenes lmo0737 lmo0737 (34.1% evalue=8.E-36) YP_070700.1 similar to Pseudomonas aeruginosa PA3757 probable transcriptional regulator (38.3% evalue=3.E-34); D. radiodurans DRA0211 transcriptional regulator, GntR family (34.9% evalue=1.E-28) YP_070701.1 similar to Yersinia pestis YPO2262 exported protein (99.8% evalue=0); Salmonella typhimurium STM1466 ydgA; periplasmic protein (43.2% evalue=1.E-111) YP_070702.1 similar to Yersinia pestis YPO2263 manA, pmi; mannose-6-phosphate isomerase (99.2% evalue=0); Escherichia coli ECs2319 mannose-6-phosphate isomerase (71.4% evalue=1.E-156) YP_070703.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_070704.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_070705.1 similar to Yersinia pestis YPO2266 membrane protein (99.1% evalue=0); Escherichia coli JW1588 ynfM; Hypothetical transcriptional regulator (69.3% evalue=1.E-160) YP_070706.1 similar to Escherichia coli b1595 ynfL; hypothetical transcriptional regulator in MLC-asr intergenic region (59.5% evalue=5.E-92); Escherichia coli JW1587 ynfL; Hypothetical transcriptional regulator (59.5% evalue=5.E-92) YP_070707.1 similar to Yersinia pestis YPO2268 mlc; ROK family transcriptional regulatory protein (99.5% evalue=0); Escherichia coli JW1586 mlc; Grobal represser of PTS system, Making large colonies protein (73.6% evalue=1.E-171) YP_070708.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_070709.2 similar to Yersinia pestis YPO2270 membrane protein (99.7% evalue=0); Salmonella typhimurium STM1490 chloride channel protein (63.9% evalue=1.E-146) YP_070710.1 similar to Escherichia coli ECs2292 hypothetical protein (56.7% evalue=2.E-18); Escherichia coli Z2573 hypothetical protein (56.7% evalue=2.E-18) YP_070711.1 similar to Salmonella typhi STY1560 secreted protein (41.5% evalue=4.E-21); Salmonella typhimurium STM1503 ynfB; periplasmic protein (41.5% evalue=4.E-21) YP_070712.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_070713.1 similar to Ralstonia solanacearum RS00474 probable transcription regulator protein (36.4% evalue=2.E-82); Pseudomonas aeruginosa PA4021 probable transcriptional regulator (35.2% evalue=1.E-78) YP_070714.1 similar to Pseudomonas aeruginosa PA4022 probable aldehyde dehydrogenase (79.2% evalue=0); Pseudomonas aeruginosa PA1984 probable aldehyde dehydrogenase (78.6% evalue=0) YP_070716.1 similar to Salmonella typhi STY2000 membrane protein (77.5% evalue=1.E-127); Salmonella typhimurium STM1862 pagO; PhoPQ-activated gene; predicted integral membrane protein (76.8% evalue=1.E-126) YP_070717.1 similar to Salmonella typhi STY1507 aminotransferase (63.8% evalue=1.E-145); Salmonella typhimurium STM1557 aminotransferase (63.3% evalue=1.E-148) YP_070718.1 similar to Yersinia pestis YPO2284 hypothetical protein (99.3% evalue=6.E-91) YP_070719.1 similar to Yersinia pestis YPO2285 ribose-binding periplasmic protein (partial) (99.5% evalue=1.E-113); Brucella melitensis BMEII0435 D-ribose-binding periplasmic protein precursor (80.6% evalue=1.E-122) YP_070720.1 similar to Mesorhizobium loti mll7011 ribose ABC transporter, permease (50.3% evalue=3.E-85); Brucella melitensis BMEII0433 ribose transport system permease RbsC (77.4% evalue=1.E-148) YP_070721.1 similar to Mesorhizobium loti mll7012 ribose ABC transporter, ATP-binding protein (48.1% evalue=1.E-127); Brucella melitensis BMEII0432 ribose transport ATP-binding protein RbsA (73.2% evalue=0) YP_070722.1 similar to Sinorhizobium meliloti SMb20350 hypothetical protein (30.4% evalue=7.E-13); Brucella melitensis BMEII0431 hypothetical protein (55.3% evalue=2.E-33) YP_070723.1 similar to Yersinia pestis YPO2286 conserved hypothetical protein (99.7% evalue=0); Clostridium acetobutylicum CAC0106 ABC-type probable sulfate transporter, periplasmic binding protein (24.8% evalue=2.E-14) YP_070724.1 similar to Yersinia pestis YPO2287 transport system permease (100% evalue=1.E-158); Bacillus subtilis BG10657 ssuC, ygaM, yzeB; aliphatic sulfonates transport system permease (36.5% evalue=4.E-45) YP_070725.1 similar to Mesorhizobium loti mll1253 ATP-binding protein of ABC transporter (45.1% evalue=3.E-62); Methanocaldococcus jannaschii MJ0412 tauB; taurine transport system ATP-binding protein (48.3% evalue=1.E-65) YP_070726.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_070727.1 similar to Yersinia pestis YPO2289 virulence factor (97.6% evalue=0); Salmonella typhimurium STM1593 srfA; ssrAB activated gene (37.8% evalue=4.E-85) YP_070728.1 similar to Yersinia pestis YPO2290 virulence factor (99.1% evalue=0); Salmonella typhimurium STM1594 srfB; ssrAB activated gene (56.8% evalue=0) YP_070729.1 similar to Yersinia pestis YPO2291 virulence factor (98.5% evalue=0); Pasteurella multocida PM1820 unknown (39.5% evalue=3.E-84) YP_070730.1 similar to Yersinia pestis YPO2292 lipoprotein (98.8% evalue=1.E-146); Salmonella typhimurium STM3036 inner membrane protein (45.1% evalue=5.E-61) YP_070731.1 catalyzes the formation of 2-acetolactate from pyruvate YP_070732.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_070733.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_070734.1 similar to Yersinia pestis YPO2297 membrane protein (99% evalue=0) YP_070735.1 similar to Yersinia pestis YPO2298 phoA; alkaline phosphatase precursor (100% evalue=0); Escherichia coli Z0479 phoA; alkaline phosphatase (74.3% evalue=0) YP_070736.1 similar to Yersinia pestis YPO2299 ogt; methylated-DNA--protein-cysteine methyltransferase (100% evalue=1.E-97); Escherichia coli Z2432 ogt; O-6-alkylguanine-DNA/cysteine-protein methyltransferase (59.1% evalue=5.E-55) YP_070737.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_070738.1 with UspC and UspD is involved in resistance to UV irradiation YP_070739.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_070740.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_070741.1 similar to Yersinia pestis YPO2304 hypothetical protein, 99% identical. YP_070742.1 similar to Yersinia pestis YPO2305 exported protein (100% evalue=1.E-178); Escherichia coli Z2603 hypothetical protein (70.3% evalue=1.E-124) YP_070743.1 similar to Yersinia pestis YPO2306 amino acid antiporter (99.7% evalue=0); Escherichia coli JW1597 arcD; arginine/ornithine antiporter (74.8% evalue=0) YP_070744.1 similar to Yersinia pestis YPO2307 conserved hypothetical protein (100% evalue=5.E-74); Vibrio cholerae VC1189 hypothetical protein (41.7% evalue=2.E-21) YP_070745.1 response regulator in two-component regulatory system with RstB YP_070746.1 similar to Yersinia pestis YPO2309 rstB, uspT; two-component regulatory system, sensor kinase (99.2% evalue=0); Salmonella typhimurium STM1471 rstB; sensory histidine kinase in two-component regulatory system with RstA (70% evalue=1.E-171) YP_070747.1 similar to Yersinia pestis YPO2310 carboxypeptidase (99.3% evalue=0); Vibrio cholerae VC1414 thermostable carboxypeptidase 1 (55.8% evalue=1.E-159) YP_070748.1 similar to Yersinia pestis YPO2380 sepC; insecticial toxin (72.3% evalue=0) YP_070749.1 similar to Yersinia pestis YPO2315 exported protein (100% evalue=1.E-108); Salmonella typhi STY1194 exported protein (80.1% evalue=5.E-87) YP_070750.1 similar to Yersinia pestis YPO2316 membrane protein (100% evalue=1.E-104); Salmonella typhimurium STM1158 inner membrane protein (62.6% evalue=4.E-68) YP_070751.1 similar to Yersinia pestis YPO2317 hypothetical protein, 100% identical. YP_070752.1 similar to Yersinia pestis YPO2318 acid shock protein, 93% identical YP_070753.1 similar to Yersinia pestis YPO2319 pepetidase (98.5% evalue=1.E-156); Escherichia coli JW1590 hypothetical protein (61.8% evalue=1.E-87) YP_070754.1 similar to Yersinia pestis YPO3485 transcriptional regulatory protein (38.6% evalue=5.E-08) YP_070755.1 similar to Yersinia pestis YPO2321 phage protein (99% evalue=1.E-53) YP_070756.2 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_070757.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_070758.1 similar to Yersinia pestis YPO2324 transcriptional regulatory protein (100% evalue=0); Ralstonia solanacearum RS01477 dalR, RSc2127; transcriptional regulator (repressor) transcription regulator protein (53.3% evalue=3.E-90) YP_070759.1 similar to Yersinia pestis YPO2325 dalD; D-arabinitol 4-dehydrogenase (99.5% evalue=0); Ralstonia solanacearum RS01475 dalD, RSc2129; D-arabinitol dehydrogenase oxidoreductase (59.3% evalue=1.E-153) YP_070760.1 similar to Yersinia pestis YPO2326 exported protein (100% evalue=9.E-65); Salmonella typhimurium STM1644 ydbL; periplasmic protein (60% evalue=6.E-27) YP_070761.1 similar to Yersinia pestis YPO2327 lipoprotein (98.3% evalue=3.E-27); Salmonella typhi STY1424 lipoprotein (68.5% evalue=1.E-13) YP_070762.1 similar to Yersinia pestis YPO2328 membrane protein (99.7% evalue=0); Escherichia coli b1381 ydbH; hypothetical 96.8 kD protein in ldhA-tynA intergenic region (46.5% evalue=0) YP_070763.1 Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthes YP_070764.1 similar to Yersinia pestis YPO2330 hslJ; heat shock protein (100% evalue=3.E-84); Escherichia coli Z2330 hslJ; heat shock protein hslJ (44.7% evalue=1.E-27) YP_070765.1 similar to Yersinia pestis YPO2331 lipoprotein (99.1% evalue=5.E-61); Escherichia coli JW1373 ydbJ; Hypothetical protein (56.2% evalue=5.E-10) YP_070766.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli YP_070767.1 similar to Yersinia pestis YPO2333 qacE; quaternary ammonium compound-resistance protein (100% evalue=1.E-56); Brucella melitensis BMEI1045 quateRNAry ammonium compound-resistance protein qacE (55.4% evalue=3.E-30) YP_070768.1 similar to Yersinia pestis YPO2334 nifJ; pyruvate-flavodoxin oxidoreductase (99.9% evalue=0); Escherichia coli b1378 ydbK; pyruvate ferredoxin oxidoreductase (80.5% evalue=0) YP_070769.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_070770.1 similar to Yersinia pestis YPO2336 exported protein (100% evalue=0); Mycobacterium tuberculosis_CDC1551MT2559 carboxylesterase family protein (35.5% evalue=8.E-27) YP_070771.1 similar to Yersinia pestis YPO2337 regulatory protein (99.2% evalue=1.E-163) YP_070772.1 similar to Yersinia pestis YPO2338 CorA-like Mg2+ transporter protein (99.6% evalue=0); Escherichia coli JW1336 hypothetical protein (64.8% evalue=1.E-125); Citation: Worlock and Smith (2002) J. Bacteriol. 184:4369-4373 YP_070773.1 similar to Yersinia pestis YPO2339 mppA; periplasmic murein peptide-binding protein (100% evalue=0); Escherichia coli b1329 oligopeptide transport system substrate-binding protein (70.5% evalue=0) YP_070774.1 similar to Yersinia pestis YPO2340 conserved hypothetical protein (99.6% evalue=1.E-145); Escherichia coli b1326 ycjI; hypothetical 28.8 kD protein in tpx-fnr itergenic region (70.5% evalue=6.E-92) YP_070775.1 similar to Yersinia pestis YPO2341 mandelate racemase / muconate lactonizing protein (100% evalue=0); Salmonella typhimurium STM1681 ycjG; chloromuconate cycloisomerase (muconate cycloisomerase) (68.2% evalue=1.E-123) YP_070776.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_070777.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_070778.1 similar to Yersinia pestis YPO2345 conserved hypothetical protein (100% evalue=2.E-81) YP_070779.1 similar to Yersinia pestis YPO2346 conserved hypothetical protein (99.3% evalue=1.E-84); Mesorhizobium loti mlr9079 hypothetical protein (34.4% evalue=9.E-08) YP_070780.1 similar to Yersinia pestis YPO2347 membrane protein (100% evalue=0); Escherichia coli ECs1901 hypothetical protein (74.3% evalue=1.E-146) YP_070781.1 similar to Yersinia pestis YPO2348 conserved hypothetical protein (100% evalue=0); Escherichia coli Z2458 ycjX; EC 2.1 enzymes (80.6% evalue=0) YP_070783.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_070784.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_070785.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_070786.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_070787.1 similar to Yersinia pestis YPO2355 sapA; peptide transport periplasmic protein precursor (99.8% evalue=0); Escherichia coli b1294 sapA; peptide transport system substrate-binding protein (76.2% evalue=0) YP_070788.1 similar to Yersinia pestis YPO2356 sapB; peptide transport system permease (100% evalue=1.E-180); Escherichia coli b1293 sapB; peptide transport system permease (76.9% evalue=1.E-146) YP_070789.1 similar to Yersinia pestis YPO2357 sapC; peptide transport system permease (100% evalue=1.E-164); Escherichia coli b1292 sapC; peptide transport system permease (77% evalue=1.E-128) YP_070790.1 similar to Yersinia pestis YPO2358 sapD; peptide transport system ATP-binding protein (100% evalue=0); Salmonella typhi STY1356 sapD; peptide transport system ATP-binding protein SapD (81.8% evalue=1.E-164) YP_070791.1 similar to Yersinia pestis YPO2359 sapF; peptide transport system ATP-binding protein (100% evalue=1.E-150); Escherichia coli JW1283 sapF; Peptide transport system ATP-binding protein (82.3% evalue=1.E-124) YP_070792.1 similar to Yersinia pestis YPO2360 conserved hypothetical protein (100% evalue=0); Escherichia coli b1287 yciW; hypothetical 45.1 kD protein in rnb-fabI intergenic region (37.8% evalue=6.E-49) YP_070793.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_070794.1 similar to Yersinia pestis YPO2362 membrane protein (100% evalue=1.E-110); Salmonella typhimurium STM2169 yohC; paral transport protein (65.4% evalue=1.E-73) YP_070795.1 similar to Yersinia pestis YPO2363 conserved hypothetical protein (100% evalue=1.E-42); Salmonella typhimurium STM4194 yjbD; cytoplasmic protein (53.4% evalue=3.E-16) YP_070796.1 similar to Yersinia pestis YPO2367 gst; glutathione S-transferase (100% evalue=1.E-111); Salmonella typhi STY1671 gst; glutathione S-transferase (61.5% evalue=7.E-71) YP_070797.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_070798.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_070799.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_070800.1 similar to Yersinia pestis YPO2371 lipoprotein (100% evalue=2.E-55); Salmonella typhimurium STM1447 ydhA; outer membrane lipoprotein (44.1% evalue=2.E-20) YP_070801.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_070802.1 similar to Yersinia pestis YPO2373 slyB, pcpY; lipoprotein (100% evalue=2.E-81); Escherichia coli ECs2350 outer membrane protein (74.8% evalue=6.E-63) YP_070803.1 Transcription regulator that can both activate or repress expression YP_070804.1 similar to Yersinia pestis YPO2375 aldo/keto reductase (100% evalue=1.E-173); Escherichia coli JW1639 ydhF; Hypothetical oxidoreductase (73.1% evalue=1.E-128) YP_070805.1 similar to Yersinia pestis YPO2376 conserved hypothetical protein (100% evalue=2.E-67); Escherichia coli JW1640 ydhL; Hypothetical protein (68.4% evalue=5.E-32) YP_070806.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_070807.1 similar to Yersinia pestis YPO2378 TetR-family transcriptional regulatory protein (100% evalue=1.E-110); Escherichia coli Z2666 hypothetical protein (51.5% evalue=1.E-47) YP_070808.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_070809.1 similar to Yersinia pestis YPO2380 sepC; insecticial toxin (99.4% evalue=0) YP_070810.1 similar to Yersinia pestis YPO2381 gloA; lactoylglutathione lyase (99.2% evalue=5.E-73); Escherichia coli b1651 gloA; lactoylglutathione lyase (80% evalue=9.E-60) YP_070811.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_070812.1 similar to Yersinia pestis YPO2383 conserved hypothetical protein (100% evalue=5.E-64); Salmonella typhi STY1689 ydhD; conserved hypothetical protein (88.6% evalue=5.E-55) YP_070813.1 similar to Yersinia pestis YPO2385 exported protein (99.3% evalue=1.E-162); Escherichia coli b1655 ydhO; hypothetical 29.9 kD protein in lhr-sodB intergenic region precursor (51.9% evalue=1.E-73) YP_070814.1 Fe; SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_070815.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_070816.1 similar to Yersinia pestis YPO2388 LysR-family transcriptional regulatory protein (99.6% evalue=0); Escherichia coli JW1651 ydhB; Hypothetical protein (70.3% evalue=1.E-128) YP_070817.1 uncharacterized member of the major facilitator superfamily (MFS) YP_070818.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_070819.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_070820.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_070821.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_070822.1 similar to Yersinia pestis YPO2394 lpp, mlpA; major outer membrane lipoprotein (100% evalue=2.E-36); Salmonella typhimurium STM1377 lpp; murein lipoprotein, links outer and inner membranes (91% evalue=3.E-33) YP_070823.1 similar to Escherichia coli ECs1491 hypothetical protein (63.4% evalue=1.E-104); Escherichia coli Z1752 ycfS; orf, hypothetical protein (63.4% evalue=1.E-104) YP_070824.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_070825.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_070826.1 with SufBC activates cysteine desulfurase SufS YP_070827.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_070828.1 with SufCD activates cysteine desulfurase SufS YP_070829.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_070830.1 similar to Yersinia pestis YPO2406 conserved hypothetical protein (100% evalue=1.E-76); Escherichia coli b1686 hypothetical protein (69.8% evalue=1.E-51) YP_070831.1 similar to Yersinia pestis YPO2407 conserved hypothetical protein (99.6% evalue=0); Escherichia coli Z2715 ydiJ; oxidase (79% evalue=0) YP_070832.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_070833.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_070834.1 similar to Yersinia pestis YPO2410 Conserved hypothetical protein (99.6% evalue=1.E-152); Escherichia coli Z2732 ydiA; orf, hypothetical protein (80.5% evalue=1.E-123) YP_070835.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_070836.1 similar to Escherichia coli b1706 hypothetical protein (64.9% evalue=0); Escherichia coli JW1696 ydiU; Hypothetical protein (64.9% evalue=0) YP_070837.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_070838.1 similar to Yersinia pestis YPO2415 nlpC; lipoprotein (100% evalue=2.E-87); Salmonella typhimurium STM1343 nlpC; lipoprotein (66.6% evalue=2.E-58) YP_070839.1 similar to Yersinia pestis YPO2416 membrane protein (100% evalue=1.E-69); Pseudomonas aeruginosa PA3558 hypothetical protein (42.9% evalue=2.E-20) YP_070840.1 similar to Yersinia pestis YPO2417 membrane protein (99.1% evalue=3.E-60); Escherichia coli JW2252 hypothetical protein (51.4% evalue=1.E-22) YP_070841.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_070842.1 similar to Yersinia pestis YPO2419 conserved hypothetical protein (100% evalue=1.E-176); Escherichia coli b2256 hypothetical protein (61.9% evalue=1.E-107) YP_070843.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_070844.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_070845.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_070846.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_070847.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_070848.1 with BtuD and BtuF transports vitamin B12 into the cell YP_070849.1 similar to Yersinia pestis YPO2981 exported protein (48.7% evalue=2.E-20) YP_070850.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_070851.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_070852.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_070854.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_070855.1 similar to Yersinia pestis YPO2431 rpmI; 50S ribosomal protein L35 (100% evalue=1.E-31); Salmonella typhimurium STM1335 rpmI; 50S ribosomal subunit protein L35 (89.2% evalue=3.E-28) YP_070856.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_070857.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_070858.1 similar to Yersinia pestis YPO2434 conserved hypothetical protein (98.5% evalue=9.E-35) YP_070859.1 similar to Yersinia pestis YPO2435 membrane protein (98.4% evalue=2.E-70) YP_070860.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_070861.1 similar to Yersinia pestis YPO2438 membrane-bound lytic murein transglycosylase (99.5% evalue=1.E-122); Escherichia coli b1193 mlte, sltz.; membrane-bound lytic murein transglycosylase E (49.7% evalue=2.E-52) YP_070862.1 similar to Yersinia pestis YPO2439 yfeA; periplasmic-binding protein (100% evalue=0); Pasteurella multocida PM0400 yfeA; Mn transport protein ABC transporter, iron (chelated) transporter, periplasmic-binding protein, (76.9% evalue=1.E-122); Citation: Bearden et al. (1998) J. Bacteriol. 180:1135-1147 YP_070863.1 similar to Yersinia pestis YPO2440 yfeB; ATP-binding transport protein (100% evalue=1.E-167); Pasteurella multocida PM0399 yfeB; iron(III) dicitrate transport ATP-binding protein,iron (chelated) transporter (72% evalue=1.E-113); Citation: Bearden et al. (1998) J. Bacteriol. 180:1135-1147 YP_070864.1 similar to Yersinia pestis YPO2441 yfeC; chelated iron transport system membrane protein (99.6% evalue=1.E-161); Pasteurella multocida PM0398 yfeC; iron (chelated) ABC transporter, permease, (74.2% evalue=1.E-113); Citation: Bearden et al. (1998) J. Bacteriol. 180:1135-1147 YP_070865.1 similar to Yersinia pestis YPO2442 yfeD; chelated iron transport system membrane protein (100% evalue=1.E-166); Pasteurella multocida PM0397 yfeD; iron (chelated) transporter, permease (64.2% evalue=1.E-102); Citation: Bearden et al. (1998) J. Bacteriol. 180:1135-1147 YP_070866.1 similar to Yersinia pestis YPO2443 hypothetical protein, 100% identical YP_070867.1 similar to Yersinia pestis YPO2444 conserved hypothetical protein (100% evalue=1.E-174); Salmonella typhi STY1787 conserved hypothetical protein (70.4% evalue=1.E-119) YP_070868.1 similar to Yersinia pestis YPO2445 yfeE; yfeABCD locus regulator (100% evalue=1.E-101); Salmonella typhi STY1788 membrane protein (67.4% evalue=2.E-68) YP_070869.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_070870.1 similar to Sinorhizobium meliloti SMb21347 pectin degradation protein (44.9% evalue=2.E-18); Clostridium acetobutylicum CAC3376 possible pectin degradation protein (sugar phosphate isomerase family) (43.9% evalue=2.E-20) YP_070871.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_070872.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_070873.1 similar to Yersinia pestis YPO3994 pelY; periplasmic pectate lyase precursor (38.7% evalue=1.E-102) YP_070874.1 similar to Yersinia pestis YPO1722 ABC sugar transporter (permease) (100% evalue=1.E-170); Agrobacterium tumefaciens AGR_L_3351 yesP; probable ABC transporter permease YesP (60.1% evalue=1.E-101) YP_070875.1 similar to Yersinia pestis YPO1721 sugar ABC transporter (permease) (100% evalue=1.E-175); Agrobacterium tumefaciens AGR_L_3353 lactose transport system (permease) (57.6% evalue=8.E-98) YP_070876.1 similar to Yersinia pestis YPO1720 sugar ABC transporter (100% evalue=0) YP_070877.1 similar to Yersinia pestis YPO1719 sugar-binding protein (100% evalue=0); Agrobacterium tumefaciens AGR_L_3359 unknown conserved protein (38.7% evalue=1.E-77) YP_070878.1 similar to Yersinia pestis YPO3995 exported protein (63.5% evalue=2.E-83) YP_070879.1 similar to Yersinia pestis YPO1717 ydjM; membrane protein (100% evalue=1.E-105); Escherichia coli ECs2434 hypothetical protein (66.4% evalue=1.E-63) YP_070880.1 similar to Yersinia pestis YPO1716 gltP; transport protein (100% evalue=0); Escherichia coli JW1718 proton glutamate symport protein (gltP) homolog (83.9% evalue=0) YP_070881.1 similar to Yersinia pestis YPO1715 ybjR; probable N-acetylmuramoyl-L-alanine amidase (98.9% evalue=1.E-160); Salmonella typhi STY0927 N-acetylmuramoyl-L-alanine amidase (48.3% evalue=1.E-66) YP_070882.1 similar to Yersinia pestis YPO1714 kdgR; IclR-family transcriptional regulatory protein (100% evalue=1.E-145); Escherichia coli JW1816 kdgR; Transcriptional regulator (86.3% evalue=1.E-123) YP_070883.1 similar to Yersinia pestis YPO1713 ogl; oligogalacturonate lyase (99.7% evalue=0) YP_070884.1 similar to Yersinia pestis YPO1712 transport protein (99.7% evalue=0); Salmonella typhimurium STM1843 transport protein (69% evalue=0) YP_070885.1 similar to Yersinia pestis YPO3881 chaperone protein (33.6% evalue=8.E-34) YP_070886.1 similar to Yersinia pestis YPO1710 fimbrial protein (100% evalue=0); Pseudomonas aeruginosa PA5284 hypothetical protein (24.2% evalue=2.E-13) YP_070887.1 similar to Yersinia pestis YPO1709 htrE; outer membrane usher protein (99.8% evalue=0); Xylella fastidiosa XF0081 outer membrane usher protein precursor (39.9% evalue=1.E-172) YP_070888.1 similar to Yersinia pestis YPO1708 ecpD; chaperone protein (100% evalue=1.E-141); Escherichia coli Z0151 ecpD; fimbrial chaperone protein (41.1% evalue=4.E-48) YP_070889.1 similar to Yersinia pestis YPO1707 fimbrial protein (99.4% evalue=4.E-97); Xylella fastidiosa XF0083 fimbrial subunit precursor (42.1% evalue=6.E-25) YP_070890.1 metalloprotease YP_070891.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_070892.1 affects solute and DNA transport through an unknown mechanism YP_070893.1 similar to Yersinia pestis YPO1703 conserved hypothetical protein (100% evalue=4.E-91); Escherichia coli ECs2542 hypothetical protein (66.4% evalue=2.E-57) YP_070894.1 similar to Yersinia pestis YPO1702 yebS; membrane protein (99.7% evalue=0); Salmonella typhimurium STM1848 yebS; inner membrane protein (67.2% evalue=1.E-166) YP_070895.1 similar to Yersinia pestis YPO1701 conserved hypothetical protein (99.6% evalue=0); Escherichia coli JW1823 pqiB; Hypothetical protein (67.8% evalue=0) YP_070896.1 similar to Yersinia pestis YPO1700 exported protein (100% evalue=1.E-101) YP_070897.1 similar to Yersinia pestis YPO1699 exported protein (99.4% evalue=4.E-95); Pseudomonas aeruginosa PA4649 hypothetical protein (41.3% evalue=6.E-29) YP_070898.1 similar to Yersinia pestis YPO1698 exported protein (98.9% evalue=5.E-99); Pseudomonas aeruginosa PA4650 hypothetical protein (34.8% evalue=3.E-22) YP_070899.1 similar to Yersinia pestis YPO1696 probable outer membrane usher protein (99.3% evalue=0); Ralstonia solanacearum RS03043 probable signal peptide protein (30.3% evalue=4.E-94) YP_070900.1 similar to Yersinia pestis YPO1695 membrane protein (98.7% evalue=0); Pseudomonas aeruginosa PA4653 hypothetical protein (42.1% evalue=2.E-58) YP_070901.1 similar to Yersinia pestis YPO1694 conserved hypothetical protein (100% evalue=5.E-42); Salmonella typhi STY1982 conserved hypothetical protein (60.2% evalue=3.E-24) YP_070902.1 similar to Yersinia pestis YPO1693 conserved hypothetical protein (99.2% evalue=3.E-70); Escherichia coli Z0414 hypothetical protein (34.9% evalue=1.E-18) YP_070903.1 similar to Yersinia pestis YPO1690 hypothetical protein (100% evalue=2.E-37); Escherichia coli Z2040 unknown protein encoded by prophage CP-933O (34.2% evalue=5.E-09) YP_070904.1 similar to Yersinia pestis YPO1689 lipoprotein (100% evalue=0); Mesorhizobium loti mlr2407 unknown protein (37.7% evalue=1.E-65) YP_070905.1 similar to Yersinia pestis YPO1688 hypothetical protein (100% evalue=1.E-43) YP_070906.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_070907.1 similar to Yersinia pestis YPO1686 exported protein (100% evalue=1.E-176) YP_070908.1 similar to Yersinia pestis YPO0902 surface protein (partial) (58.9% evalue=0) YP_070909.1 similar to Yersinia pestis YPO1683 probable N-acetylmuramoyl-L-alanine amidase (98.8% evalue=1.E-148); Pseudomonas aeruginosa PA0807 conserved hypothetical protein (61.2% evalue=1.E-85) YP_070910.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_070911.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble YP_070912.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_070913.1 methylates the MCP YP_070914.1 similar to Escherichia coli b1885 tap; methyl-accepting chemotaxis protein IV (MCP-IV) (dipeptide chemoreceptor protein) (55% evalue=1.E-142); Escherichia coli JW1874 tap (55% evalue=1.E-142) YP_070915.1 similar to Yersinia pestis YPO1675 cheD; methyl-accepting chemotaxis protein (99.8% evalue=0); Salmonella typhimurium STM4533 tsr; methyl-accepting chemotaxis protein I, serine sensor receptor (68.7% evalue=0) YP_070916.2 similar to Yersinia pestis YPO1674 lipoprotein (99.5% evalue=1.E-133); Escherichia coli ECs4631 replicase (29.9% evalue=3.E-18) YP_070917.1 similar to Yersinia pestis YPO1673 integral membrane protein (97.3% evalue=0); Mesorhizobium loti mlr7771 unknown protein (26.6% evalue=1.E-44) YP_070918.1 similar to Yersinia pestis YPO1667 cheW; chemotaxis protein CheW (99.3% evalue=9.E-85); Escherichia coli ECs2597 positive regulator of CheA protein activity (84.6% evalue=1.E-72) YP_070919.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_070920.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_070921.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_070922.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_070923.1 similar to Yersinia pestis YPO1661 mgtB; Mg(2+) transport ATPase B (99.7% evalue=0); Pseudomonas aeruginosa PA4825 mgtA; Mg(2+) transport ATPase, P-type 2 (75.1% evalue=0) YP_070924.1 similar to Yersinia pestis YPO1660 mgtC; Mg(2+) transport ATPase C (99.5% evalue=1.E-126); Salmonella typhi STY4022 mgtC; conserved hyopthetical protein (63.3% evalue=4.E-72) YP_070925.1 similar to Salmonella typhimurium STM1626 trg; methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor (60.3% evalue=1.E-159); Escherichia coli JW1417 trg (58% evalue=1.E-158) YP_070926.1 similar to Yersinia pestis YPO1656 conserved hypothetical protein (100% evalue=1.E-30); Salmonella typhi STY2191 dsrB; DsrB protein (79.3% evalue=8.E-23) YP_070927.1 similar to Yersinia pestis YPO1746 cspC, msmB; cold shock protein (86.3% evalue=7.E-28) YP_070928.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_070929.1 similar to Yersinia pestis YPO1653 probable Zinc-binding dehydrogenase (99.4% evalue=0); Brucella melitensis BMEI0302 quinone oxidoreductase (61.9% evalue=1.E-113) YP_070930.1 similar to Yersinia pestis YPO1652 ylaC; membrane protein (100% evalue=2.E-98); Escherichia coli Z0570 ylaC; orf, hypothetical protein (34.4% evalue=6.E-25) YP_070931.1 similar to Yersinia pestis YPO1651 AsnC-family transcriptional regulatory protein (100% evalue=2.E-79); Sinorhizobium meliloti SMc00425 transcription regulator protein (52% evalue=3.E-42) YP_070932.1 similar to Yersinia pestis YPO1650 hypothetical protein (99% evalue=1.E-173); Ralstonia solanacearum RS04392 hypothetical protein (41% evalue=3.E-55) YP_070933.1 similar to Yersinia pestis YPO1649 conserved hypothetical protein (100% evalue=2.E-31); Salmonella typhi HCM2.0096 hypothetical protein (44.6% evalue=2.E-07) YP_070934.1 similar to Yersinia pestis YPO1648 probable histidine acid phosphatase / 6-phytase (99.7% evalue=0); Escherichia coli JW0963 appA; acid phosphatase / 6-phytase (45.8% evalue=1.E-100) YP_070935.1 similar to Yersinia pestis YPO1646 conserved hypothetical protein (100% evalue=5.E-68); Escherichia coli ECs5189 hypothetical protein (62.2% evalue=8.E-40) YP_070936.1 similar to Yersinia pestis YPO1645 conserved hypothetical protein (99.2% evalue=1.E-154); Escherichia coli ECs5190 oxidoreductase (66.3% evalue=1.E-98) YP_070937.1 similar to Yersinia pestis YPO1644 aer, air; methyl-accepting chemotaxis protein (99.8% evalue=0); Ralstonia solanacearum RS03168 aer, RSp1224; probable aerotaxis sensor receptor (chemotaxis transducer) transmembrane protein (53.6% evalue=1.E-144) YP_070938.1 similar to Yersinia pestis YPO1643 hypothetical protein (100% evalue=2.E-42) YP_070939.1 similar to Yersinia pestis YPO1642 cscR; sucrose operon repressor LacI-family (99.4% evalue=0); Escherichia coli ECs3244 sucrose operon repressor (60% evalue=1.E-113) YP_070940.1 Converts isocitrate to alpha ketoglutarate YP_070941.1 similar to Yersinia pestis YPO1640 ymfC; pseudouridine synthase (100% evalue=1.E-118); Escherichia coli JW1121 ymfC; Hypothetical protein (73.4% evalue=5.E-87) YP_070942.1 similar to Yersinia pestis YPO1639 conserved hypothetical protein (99.3% evalue=9.E-85); Escherichia coli Z1863 phosphohydrolase (75.5% evalue=1.E-64) YP_070943.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_070944.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_070945.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_070946.1 similar to Yersinia pestis YPO1635 lipoprotein (100% evalue=1.E-117) YP_070947.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_070948.1 similar to Yersinia pestis YPO1633 phoQ; sensor protein kinase (100% evalue=0); Salmonella typhi STY1270 phoQ; sensor protein PhoQ, regulator of virulence determinants (62.5% evalue=1.E-172) YP_070949.1 similar to Yersinia pestis YPO1632 conserved hypothetical protein (100% evalue=0); Salmonella typhimurium STM1229 ycfD; cytoplasmic protein (78.7% evalue=0) YP_070950.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_070951.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_070952.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_070953.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_070954.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_070955.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_070956.1 similar to Yersinia pestis YPO1625 mfd; transcription-repair coupling factor (99.6% evalue=0); Escherichia coli ECs1492 transcription-repair coupling factor (80.8% evalue=0) YP_070957.1 similar to Yersinia pestis YPO1624 ycfJ; exported protein (99.4% evalue=4.E-98); Escherichia coli JW1096 ycfJ; Hypothetical protein (80.3% evalue=4.E-84) YP_070958.1 similar to Yersinia pestis YPO1620 hypothetical protein (100% evalue=7.E-76) YP_070959.1 similar to Yersinia pestis YPO3066 hypothetical protein (53.8% evalue=2.E-47) YP_070960.1 similar to Yersinia pestis YPO1617 ndh; NADH dehydrogenase (99.7% evalue=0); Escherichia coli JW1095 ndh; NADH dehydrogenase (82.2% evalue=0) YP_070961.1 similar to Yersinia pestis YPO1616 conserved hypothetical protein (100% evalue=1.E-105); Salmonella typhi STY1250 conserved hypothetical protein (80.5% evalue=2.E-86) YP_070962.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_070963.1 similar to Yersinia pestis YPO1614 conserved hypothetical protein (99.6% evalue=1.E-159); Escherichia coli ECs1484 beta-glucosidase (37.4% evalue=9.E-34) YP_070964.1 similar to Yersinia pestis YPO1613 lipoprotein (99.4% evalue=1.E-103); Salmonella typhimurium STM1207 ycfM; outer membrane lipoprotein (49.2% evalue=3.E-48) YP_070965.1 similar to Yersinia pestis YPO1612 ycfL; lipoprotein (100% evalue=7.E-68); Escherichia coli ECs1482 hypothetical protein (46.3% evalue=1.E-21) YP_070966.1 similar to Yersinia pestis YPO1611 conserved hypothetical protein (100% evalue=9.E-63); Salmonella typhi STY1245 protein kinase C inhibitor (86.3% evalue=4.E-55) YP_070967.1 catalyzes the conversion of shikimate to 3-dehydroshikimate YP_070968.1 similar to Salmonella typhimurium STM2729 Fels-2 prophage: similar to retron in E coli (36.9% evalue=1.E-07); Escherichia coli Z2978 replication protein for prophage CP-933T (37.3% evalue=1.E-07) YP_070971.1 similar to Pyrococcus furiosus C2133PF1167 smc-like (22% evalue=4.E-07); C. perfringens CPE1884 hypothetical protein (23.1% evalue=4.E-07) YP_070973.1 similar to Salmonella typhi STY4628 probable capsid portal protein (52.4% evalue=7.E-41); Ralstonia solanacearum RS03510 probable bacteriophage protein (59.1% evalue=2.E-41) YP_070975.1 similar to Yersinia pestis YPO1877 hypothetical protein (38.8% evalue=9.E-08) YP_070976.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_070977.1 similar to Yersinia pestis YPO1607 deoxyribonuclease (100% evalue=1.E-153); Salmonella typhimurium STM1202 ycfH; deoxyribonuclease (77.5% evalue=1.E-112) YP_070978.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_070979.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_070980.1 similar to Yersinia pestis YPO1604 yceG; exported protein (99.4% evalue=0); Escherichia coli b1097 yceG; hypothetical 38.2 kD protein in pABC-holB intergenic region (63.1% evalue=1.E-117) YP_070981.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_070982.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_070983.1 carries the fatty acid chain in fatty acid biosynthesis YP_070984.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_070985.1 similar to Yersinia pestis YPO1598 fabD, tfpA; malonyl CoA-acyl carrier protein transacylase (100% evalue=1.E-172); Salmonella typhimurium STM1194 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase (79.8% evalue=1.E-139) YP_070986.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_070987.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_070988.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_070989.1 similar to Yersinia pestis YPO1594 conserved hypothetical protein (100% evalue=2.E-95); Escherichia coli JW1074 yceD; Hypothetical protein (79.6% evalue=3.E-75) YP_070990.2 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_070991.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_070992.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_070994.1 similar to Yersinia pestis YPO1588 conserved hypothetical protein (100% evalue=9.E-48); Neisseria meningitidis NMB1575 conserved hypothetical protein (38.7% evalue=2.E-17) YP_070995.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_070996.1 similar to Yersinia pestis YPO1586 dinI; DNA-damage-inducible protein I (100% evalue=7.E-40); Escherichia coli b1061 dinI; DNA-damage-inducible protein I (62.9% evalue=2.E-22) YP_070997.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_070998.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_070999.1 similar to Yersinia pestis YPO2449 LuxR-family regulatory protein (95% evalue=1.E-108); Salmonella typhimurium STM4337 ecnR; bacterial regulatory protein, luxR family (29.4% evalue=8.E-13) YP_071000.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_071001.1 similar to Yersinia pestis YPO2451 conserved hypothetical protein (100% evalue=0); Escherichia coli JW1042 yceA; Hypothetical protein (ORF39.9) (73.8% evalue=1.E-158) YP_071002.1 similar to Yersinia pestis YPO2453 membrane protein (99.1% evalue=3.E-64) YP_071003.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_071004.1 similar to Listeria innocua lin0564 similar to di-tripeptide transporter (37.6% evalue=6.E-84); Bacillus subtilis BG12027 yclF; di-tripeptide transport system permease (36.2% evalue=2.E-89) YP_071005.1 similar to Escherichia coli ECs1428 hypothetical protein (64.8% evalue=6.E-27); Escherichia coli Z1685 yceK; orf; Unknown function (64.8% evalue=6.E-27) YP_071006.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_071007.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_071009.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_071010.1 similar to Yersinia pestis YPO2455 membrane protein (99% evalue=1.E-119); Salmonella typhimurium STM4395 yifZ; permease (71.9% evalue=1.E-119) YP_071011.1 similar to Yersinia pestis YPO2456 ypeI; N-acylhomoserine lactone synthase YpeI (100% evalue=1.E-121) YP_071012.1 similar to Yersinia pestis YPO2457 ypeR; quorum-sensing transcriptional activator YpeR (100% evalue=1.E-139) YP_071013.1 similar to Yersinia pestis YPO2458 LysR-family transcriptional regulator (99.3% evalue=1.E-174); Caulobacter crescentus CC1117 transcriptional regulator, LysR family (34.1% evalue=5.E-33) YP_071014.1 similar to Yersinia pestis YPO2459 transporter protein (99.7% evalue=0); Escherichia coli JW2741 ygcS; Hypothetical metabolite transport protein (62.1% evalue=1.E-157) YP_071015.1 similar to Yersinia pestis YPO2460 conserved hypothetical protein (99.4% evalue=2.E-93); A. fulgidus AF1305 hps-2; D-arabino 3-hexulose 6-phosphate formaldehyde lyase (32.7% evalue=8.E-23) YP_071016.1 similar to Yersinia pestis YPO2461 oxidoreductase (99.4% evalue=0); Listeria monocytogenes lmo2005 similar to oxidoreductase (45.3% evalue=1.E-72) YP_071017.1 similar to Yersinia pestis YPO2462 conserved hypothetical protein (100% evalue=1.E-102); Pasteurella multocida PM0308 unknown (32.6% evalue=3.E-17) YP_071018.1 similar to Yersinia pestis YPO2463 conserved hypothetical protein (99.7% evalue=0); Pasteurella multocida PM0307 unknown (55% evalue=3.E-94) YP_071019.1 similar to Yersinia pestis YPO2464 conserved hypothetical protein (98.1% evalue=0); Pasteurella multocida PM0306 unknown (32.8% evalue=2.E-34) YP_071020.1 similar to Yersinia pestis YPO2465 conserved hypothetical protein (81.2% evalue=0); Pasteurella multocida PM0305 unknown (26.9% evalue=7.E-30) YP_071021.1 similar to Yersinia pestis YPO2467 conserved hypothetical protein (99.2% evalue=0); Pasteurella multocida PM0312 unknown (42.7% evalue=0) YP_071022.1 similar to Yersinia pestis YPO2468 conserved hypothetical protein (99% evalue=0); Pasteurella multocida PM0311 unknown (57.7% evalue=1.E-103) YP_071023.1 similar to Yersinia pestis YPO2470 membrane protein (99.7% evalue=0); Salmonella typhi STY0618 ybdG; membrane protein (63.1% evalue=1.E-150) YP_071024.1 similar to Yersinia pestis YPO2471 exported protein (99.7% evalue=0) YP_071025.1 similar to Yersinia pestis YPO2472 exported protein (99.7% evalue=0) YP_071026.1 similar to Yersinia pestis YPO2473 hypothetical protein (97.7% evalue=0); Listeria monocytogenes lmo0863 lmo0863 (47.3% evalue=3.E-70) YP_071027.1 similar to Yersinia pestis YPO2474 conserved hypothetical protein (99.7% evalue=0); Listeria monocytogenes lmo0864 lmo0864 (47.1% evalue=1.E-92) YP_071028.1 similar to Yersinia pestis YPO2475 sugar ABC transporter, permease (100% evalue=1.E-152); Thermotoga maritima TM1853 multiple sugar transport system permease (52.9% evalue=4.E-86) YP_071029.1 similar to Yersinia pestis YPO2476 sugar ABC transporter, permease (99.3% evalue=1.E-164); Thermotoga maritima TM1854 multiple sugar transport system permease (54.5% evalue=9.E-96) YP_071030.1 similar to Yersinia pestis YPO2477 solute-binding protein (99.7% evalue=0); Thermotoga maritima TM1855 multiple sugar transport system substrate-binding protein (50% evalue=1.E-114) YP_071031.1 similar to Yersinia pestis YPO2478 LacI-family transcriptional regulatory protein (100% evalue=0); Mycobacterium tuberculosis Rv3575c hypothetical protein Rv3575c (34.2% evalue=6.E-46) YP_071032.1 similar to Yersinia pestis YPO2479 manB, rfbK, rfbK2; phosphomannomutase (100% evalue=0); Salmonella typhimurium STM2104 cpsG; phosphomannomutase in colanic acid gene cluster (61.8% evalue=1.E-163) YP_071033.1 similar to Yersinia pestis YPO2480 mtlK; mannitol transport ATP-binding protein (99.7% evalue=0); Agrobacterium tumefaciens AGR_L_3324 lacK; lactose transport ATP-binding protein LacK (49.7% evalue=9.E-93) YP_071034.1 similar to Yersinia pestis YPO2481 exported protein (100% evalue=4.E-95) YP_071035.1 similar to Yersinia pestis YPO2488 hypothetical protein (97.5% evalue=1.E-43) YP_071036.1 similar to Yersinia pestis YPO2489 conserved hypothetical protein (100% evalue=3.E-96); Neisseria meningitidis NMB0222 hypothetical protein (36.5% evalue=9.E-27) YP_071037.2 similar to Yersinia pestis YPO2490 hemolysin (99.2% evalue=0) YP_071038.1 similar to Yersinia pestis YPO2491 hemolysin activator protein (99.8% evalue=0) YP_071039.1 similar to Yersinia pestis YPO2492 dioxygenase beta subunit (99.6% evalue=0); Escherichia coli JW1792 yeaX; dioxygenase alpha subunit (58.8% evalue=1.E-105) YP_071040.1 similar to Yersinia pestis YPO2493 dioxygenase alpha subunit (100% evalue=0); Escherichia coli JW1791 yeaW; dioxygenase alpha subunit (82.6% evalue=0) YP_071041.2 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function YP_071042.1 similar to Yersinia pestis YPO2496 tartrate dehydrogenase (100% evalue=0); Escherichia coli b1800 yeaU; probable tartrate dehydrogenase (81.3% evalue=1.E-174) YP_071043.1 similar to Yersinia pestis YPO2497 LlysR-family transcriptional regulatory protein (99.6% evalue=1.E-179); Escherichia coli Z2842 yeaT; transcriptional regulator LYSR-type (74.5% evalue=1.E-130) YP_071044.1 similar to Yersinia pestis YPO2498 LacI-family transcriptional regulatory protein (99.4% evalue=0); Escherichia coli ECs4695 regulator for rbs operon (27.7% evalue=9.E-28) YP_071045.1 similar to Yersinia pestis YPO2499 rbsC; sugar transport system, permease (100% evalue=0); Agrobacterium tumefaciens AGR_L_1078 ribose ABC transporter (permease) (59% evalue=3.E-99) YP_071046.1 similar to Yersinia pestis YPO2500 rbsA; sugar transport system, ATP-binding protein (98.7% evalue=0); Agrobacterium tumefaciens Atu4321 rbsA; ABC transporter, nucleotide binding/ATPase [ribose] (58.3% evalue=1.E-152) YP_071047.1 similar to Yersinia pestis YPO2501 rbsB; sugar binding protein precursor (99.3% evalue=1.E-166); Agrobacterium tumefaciens Atu4320 rbsB; ABC transporter, substrate binding protein [ribose] (59.4% evalue=3.E-97) YP_071048.1 similar to Yersinia pestis YPO3352 ydjJ; Zinc-binding dehydrogenase (52% evalue=1.E-110) YP_071049.1 similar to Yersinia pestis YPO2504 hypothetical protein (27.2% evalue=4.E-11) YP_071050.1 similar to Yersinia pestis YPO2504 hypothetical protein (61.7% evalue=2.E-56) YP_071051.1 similar to Yersinia pestis YPO2505 membrane protein (99% evalue=1.E-176); Sinorhizobium meliloti SMa0683 hypothetical protein (40.2% evalue=6.E-64) YP_071052.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_071053.1 similar to Yersinia pestis YPO2507 membrane protein (100% evalue=1.E-162); Salmonella typhimurium STM0832 ybiF; permease (71.4% evalue=1.E-115) YP_071054.1 similar to Yersinia pestis YPO2508 conserved hypothetical protein (100% evalue=1.E-93); Anabaena all4397 acetyltransferase (32.5% evalue=6.E-18) YP_071055.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_071056.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_071057.1 similar to Yersinia pestis YPO2511 exported protein (100% evalue=0); Listeria innocua lin2536 lin2536 (27.1% evalue=2.E-07) YP_071058.1 similar to periplasmic-binding component of ABC transporters YP_071059.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_071060.1 similar to ATP-binding component of ABC transporters YP_071061.1 similar to Yersinia pestis YPO2515 chemotactic transducer (98.5% evalue=0); Pseudomonas aeruginosa PA1423 probable chemotaxis transducer (41.5% evalue=7.E-90) YP_071063.1 similar to Yersinia pestis YPO2519 conserved hypothetical protein (99.7% evalue=0); Escherichia coli JW0792 ybiN; Hypothetical protein (57% evalue=1.E-95) YP_071064.1 similar to Yersinia pestis YPO2521 exported protein (100% evalue=8.E-41); Salmonella typhimurium STM0823 ybiJ; periplasmic protein (59.3% evalue=6.E-21) YP_071065.1 similar to Yersinia pestis YPO2522 ybiB; glycosyl transferase (99.3% evalue=1.E-178); Salmonella typhimurium STM0822 ybiB; transferase (60.1% evalue=1.E-103) YP_071066.1 similar to Yersinia pestis YPO2523 menE; O-succinylbenzoic acid--CoA ligase (99.5% evalue=0); Salmonella typhi STY2535 menE; O-succinylbenzoic acid-CoA ligase (57.2% evalue=1.E-144) YP_071067.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_071068.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_071069.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_071070.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_071071.2 synthesizes isochorismate acid from chorismate YP_071072.1 similar to Yersinia pestis YPO2530 conserved hypothetical protein (100% evalue=1.E-122) YP_071073.1 similar to Yersinia pestis YPO2531 elaB; membrane protein (100% evalue=3.E-54); Escherichia coli b2266 elaB; elaB protein (50% evalue=2.E-21) YP_071074.1 similar to Yersinia pestis YPO2532 hypothetical protein, 100 % identical. YP_071075.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_071076.1 similar to Yersinia pestis YPO2534 conserved hypothetical protein (99.4% evalue=7.E-93); Sinorhizobium meliloti SMc03110 conserved hypothetical protein (40.1% evalue=6.E-31) YP_071077.1 similar to Yersinia pestis YPO2535 sugar transporter (99.5% evalue=0); Pseudomonas aeruginosa PA2262 probable 2-ketogluconate transporter (32.6% evalue=1.E-64) YP_071078.1 similar to Yersinia pestis YPO2536 D-isomer specific 2-hydroxyacid dehydrogenase family protein (98.7% evalue=1.E-173); Agrobacterium tumefaciens AGR_L_379 D-isomer specific 2-hydroxyacid dehydrogenase; 59386-58329 (44.9% evalue=7.E-73) YP_071079.1 similar to Yersinia pestis YPO2537 LacI-family transcriptional regulatory protein (99.3% evalue=0); Salmonella typhimurium STM4481 idnR; L-idonate regulator (GalR/LacI family) (50% evalue=2.E-91) YP_071080.1 similar to Yersinia pestis YPO2538 lipoprotein (98.8% evalue=0); Escherichia coli JW1486 hypothetical protein (59.7% evalue=1.E-154) YP_071081.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_071082.1 similar to Yersinia pestis YPO3953 gluconokinase (65.8% evalue=2.E-61) YP_071083.1 similar to Yersinia pestis YPO2541 conserved hypothetical protein (100% evalue=2.E-84); Salmonella typhimurium STM3669 yiaL; cytoplasmic protein (34.2% evalue=1.E-17) YP_071084.1 similar to Yersinia pestis YPO2542 hypothetical protein (61.4% evalue=1.E-130) YP_071085.1 Catalyzes the transfer of electrons from NADH to quinone YP_071086.1 Catalyzes the transfer of electrons from NADH to quinone YP_071087.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_071088.1 Catalyzes the transfer of electrons from NADH to quinone YP_071089.1 Catalyzes the transfer of electrons from NADH to quinone YP_071090.1 Catalyzes the transfer of electrons from NADH to quinone YP_071091.1 Catalyzes the transfer of electrons from NADH to quinone YP_071092.1 Catalyzes the transfer of electrons from NADH to quinone YP_071093.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_071094.1 Catalyzes the transfer of electrons from NADH to quinone YP_071095.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_071096.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_071097.1 Catalyzes the transfer of electrons from NADH to quinone YP_071098.1 similar to Yersinia pestis YPO2556 pecT, hexA; LysR-family transcriptional regulatory protein (100% evalue=1.E-174); Salmonella typhimurium STM2330 lrhA; NADH dehydrogenase transcriptional repressor (LysR family) (72% evalue=1.E-118) YP_071099.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_071100.1 similar to Yersinia pestis YPO2559 conserved hypothetical protein (99.4% evalue=1.E-108); Escherichia coli ECs3175 alpha helix protein (80.9% evalue=9.E-86) YP_071101.1 similar to Yersinia pestis YPO2560 exported protein (97.1% evalue=1.E-33) YP_071102.1 similar to Yersinia pestis YPO2561 ion transport protein (99.6% evalue=0); Escherichia coli Z3553 yfbS; transport protein (71.4% evalue=0) YP_071103.2 similar to Yersinia pestis YPO2562 haloacid dehalogenase-like hydrolase (98.6% evalue=1.E-120); Escherichia coli ECs3177 phosphatase (71.9% evalue=6.E-85) YP_071104.1 similar to Yersinia pestis YPO2563 conserved hypothetical protein (100% evalue=4.E-93); Escherichia coli ECs3178 hypothetical protein (80.4% evalue=3.E-78) YP_071105.1 similar to Yersinia pestis YPO2564 conserved hypothetical protein (99.3% evalue=3.E-85); Salmonella typhimurium STM2336 cytoplasmic protein (71.5% evalue=1.E-61) YP_071106.1 similar to Yersinia pestis YPO2565 hypothetical protein, 98% identical. YP_071107.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_071108.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_071109.1 similar to Yersinia pestis YPO2568 LacI-family transcriptional regulatory protein (99.7% evalue=0); Salmonella typhimurium STM2345 transcriptional regulator (41.4% evalue=8.E-67) YP_071110.1 similar to Yersinia pestis YPO2569 phosphotransferase enzyme II, A component (99.3% evalue=9.E-77); Salmonella typhi STY2574 sugar phosphotransferase component II A (44.8% evalue=3.E-32) YP_071111.1 similar to Salmonella typhimurium STM2343 sugar phosphotransferase component IIB (42.5% evalue=1.E-13); C. perfringens CPE0522 PTS system, mannitol-specific II component (39.3% evalue=3.E-14) YP_071112.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_071113.1 similar to Yersinia pestis YPO2781 conserved hypothetical protein (100% evalue=1.E-104); Salmonella typhi STY2576 conserved hypothetical protein (81.5% evalue=3.E-79) YP_071114.1 similar to Yersinia pestis YPO2780 conserved hypothetical protein (93% evalue=5.E-90); Escherichia coli b2300 yfcE; hypothetical 20.1 kD protein in PTA-folX intergenic region (69% evalue=4.E-69) YP_071115.1 similar to Yersinia pestis YPO2779 conserved hypothetical protein (98.7% evalue=1.E-130); Salmonella typhi STY1354 conserved hypothetical protein (33.7% evalue=2.E-28) YP_071116.1 similar to Yersinia pestis YPO2778 conserved hypothetical protein (100% evalue=1.E-174); Escherichia coli JW2301 hypothetical protein (68.7% evalue=1.E-117) YP_071117.1 similar to Yersinia pestis YPO2777 hisP; histidine transport ATP-binding protein HisP (99.6% evalue=1.E-146); Escherichia coli ECs3190 ATP-binding component of histidine transport (86.7% evalue=1.E-122) YP_071118.1 similar to Yersinia pestis YPO2776 hisM; histidine transport system permease HisM (100% evalue=1.E-133); Escherichia coli ECs3191 histidine transport system membrane protein M (81.5% evalue=1.E-113) YP_071119.1 similar to Yersinia pestis YPO2775 hisQ; histidine transport system permease HisQ (100% evalue=1.E-125); Escherichia coli JW2305 hisQ; Histidine transport system permease HisQ (77.6% evalue=5.E-97) YP_071120.1 similar to Yersinia pestis YPO2774 hisJ; histidine-binding periplasmic protein (100% evalue=1.E-144); Escherichia coli JW2306 hisJ; Histidine-binding periplasmic protein precursor (hbp) (76.4% evalue=1.E-112) YP_071121.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_071122.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_071123.1 membrane protein required for colicin V production YP_071124.1 similar to Yersinia pestis YPO2770 dedD; membrane protein (99.5% evalue=1.E-132); Escherichia coli Z3576 dedD; lipoprotein (56.7% evalue=2.E-62) YP_071125.1 similar to Yersinia pestis YPO2769 folC, dedC; dihydrofolate synthase / folylpolyglutamate synthase (100% evalue=0); Salmonella typhimurium STM2365 folC (65.2% evalue=1.E-156) YP_071126.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_071127.1 similar to Yersinia pestis YPO2767 dedA; membrane protein (100% evalue=1.E-122); Salmonella typhimurium STM2367 dedA; DedA family (85.1% evalue=1.E-105) YP_071128.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_071129.1 similar to Yersinia pestis YPO2765 asd, usg-1; aspartate-semialdehyde dehydrogenase (100% evalue=0); Salmonella typhi STY2600 usg; semialdehyde dehydrogenase (71.5% evalue=1.E-136) YP_071130.1 catalyzes the formation of 3-hydroxy-4-phospho-hydroxy-alpha-ketobutyrate from erythronate-4-phosphate YP_071131.1 similar to Yersinia pestis YPO2762 AraC-family regulatory protein (99.2% evalue=1.E-148); Vibrio cholerae VCA0937 transcriptional regulator, AraC/XylS family (46% evalue=2.E-61) YP_071132.1 similar to Yersinia pestis YPO2761 membrane protein (99.3% evalue=1.E-169); Agrobacterium tumefaciens Atu5339 conserved hypothetical protein (46.9% evalue=6.E-71) YP_071133.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_071134.1 similar to Yersinia pestis YPO2759 smfA, mrpA; mannose-resistant/Proteus-like fimbrial protein (99.4% evalue=1.E-91); Salmonella typhimurium STM0195 stfA; fimbrial subunit (37.3% evalue=9.E-20) YP_071135.1 similar to Yersinia pestis YPO2758 aspartate/glutamate racemase (99.5% evalue=1.E-127); Salmonella typhi STY3159 ygeA; conserved hypothetical protein (58.5% evalue=7.E-76) YP_071136.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_071137.2 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_071138.1 similar to Yersinia pestis YPO2755 conserved hypothetical protein (100% evalue=1.E-46); Salmonella typhimurium STM2380 yfcL; cytoplasmic protein (69.6% evalue=3.E-28) YP_071139.1 similar to Yersinia pestis YPO2754 conserved hypothetical protein (98.8% evalue=1.E-107); Escherichia coli ECs3210 transporting ATPase (71.2% evalue=2.E-77) YP_071140.1 similar to Yersinia pestis YPO2753 yfcA; membrane protein (100% evalue=1.E-148); Escherichia coli ECs3211 structural protein (72.1% evalue=1.E-107) YP_071141.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_071142.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_071143.1 involved in methylation of ribosomal protein L3 YP_071144.1 similar to Yersinia pestis YPO2749 conserved hypothetical protein (100% evalue=1.E-101); Escherichia coli Z3594 hypothetical protein (72.7% evalue=1.E-73) YP_071145.1 similar to Yersinia pestis YPO2748 sixA; phosphohistidine phosphatase (100% evalue=4.E-90); Salmonella typhimurium STM2387 sixA; phosphohistidine phosphatase (66.4% evalue=3.E-54) YP_071146.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_071147.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_071148.1 similar to Yersinia pestis YPO2745 conserved hypothetical protein (100% evalue=6.E-52); Escherichia coli Z3606 hypothetical protein (63.8% evalue=1.E-29) YP_071149.1 similar to Yersinia pestis YPO2744 fadL, ttr; long-chain fatty acid transport protein (99.7% evalue=0); Salmonella typhimurium STM2391 fadL; transport of long-chain fatty acids; sensitivity to phage T2 (64.4% evalue=1.E-168) YP_071150.1 similar to Yersinia pestis YPO2743.1 vcaJ; VacJ lipoprotein (100% evalue=1.E-147); Escherichia coli ECs3229 lipoprotein precursor (75% evalue=1.E-110) YP_071151.1 similar to Yersinia pestis YPO2743 cytochrome c-type biogenesis protein (99.7% evalue=0); Salmonella typhimurium STM3812 ccmH; heme lyase subunit, cytochrome c-type biogenesis (54.8% evalue=1.E-55) YP_071152.1 similar to Yersinia pestis YPO2741 ccmH; cytochrome c-type biogenesis protein (100% evalue=5.E-91); Escherichia coli Z3451 ccmH; cytochrome C-type biogenesis protein ccmH (60.3% evalue=4.E-40) YP_071153.1 similar to Yersinia pestis YPO2740 ccmG, dsbE; thiol:disulfide interchange protein DsbE (100% evalue=1.E-107); Escherichia coli b2195 dsbE, ccmG; thiol:disulfide interchange protein dsbE precursor (cytochrome C biogenesis protein ccmg) (73.2% evalue=2.E-76) YP_071154.1 similar to Yersinia pestis YPO2739 ccmF; cytochrome c-type biogenesis protein (99.8% evalue=0); Escherichia coli b2196 ccmF; cytochrome C-type biogenesis protein ccmF (70.9% evalue=0) YP_071155.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_071156.1 similar to Yersinia pestis YPO2737 ccmD; heme exporter protein D (86.2% evalue=7.E-50); Escherichia coli b2198 ccmD; hemE exporter protein D (cytochrome C-type biogenesis protein ccmD) (50.7% evalue=1.E-15) YP_071157.1 similar to Yersinia pestis YPO2736 ccmC; heme exporter protein C (99.5% evalue=1.E-145); Escherichia coli b2199 ccmC; hemE exporter protein C (cytochrome C-type biogenesis protein ccmC) (76.2% evalue=1.E-112) YP_071158.1 similar to Yersinia pestis YPO2735 ccmB; heme exporter protein B (100% evalue=1.E-116); Escherichia coli b2200 ccmB; hemE exporter protein B (cytochrome C-type biogenesis protein ccmB) (77.1% evalue=7.E-91) YP_071159.1 ATP-binding protein; required for proper cytochrome c maturation YP_071160.1 similar to Yersinia pestis YPO2733 exported protein (98.7% evalue=2.E-84) YP_071161.1 similar to Yersinia pestis YPO2732 lemA; exported protein (100% evalue=3.E-97); Agrobacterium tumefaciens AGR_C_1138 lemA; lemA protein (49.4% evalue=2.E-43) YP_071162.1 similar to Yersinia pestis YPO2731 membrane protein (99.7% evalue=0); Escherichia coli b1268 yciQ; hypothetical 71.3 kD protein in trpL-btuR intergenic region (ORF2/3) (27.8% evalue=5.E-59) YP_071163.1 similar to Yersinia pestis YPO2730 conserved hypothetical protein (99.1% evalue=2.E-62); Salmonella typhi STY4488 phnA; conserved hypothetical protein (72% evalue=3.E-43) YP_071164.1 similar to Yersinia pestis YPO2729 membrane protein (100% evalue=2.E-60) YP_071165.1 similar to Yersinia pestis YPO2728 conserved hypothetical protein (100% evalue=2.E-88); Salmonella typhi STY0290 conserved hypothetical protein (38.7% evalue=6.E-21) YP_071166.1 similar to Yersinia pestis YPO2727 conserved hypothetical protein (98.8% evalue=1.E-154); Pseudomonas aeruginosa PA0086 hypothetical protein (37.7% evalue=1.E-39) YP_071167.1 similar to Yersinia pestis YPO2726 hypothetical protein (100% evalue=1.E-164) YP_071168.1 similar to Salmonella typhi STY0321 Rhs-family protein (39.7% evalue=2.E-07); Ralstonia solanacearum RS01806 probable transmembrane protein (47.2% evalue=6.E-09) YP_071169.1 similar to Yersinia pestis YPO2725 conserved hypothetical protein (100% evalue=0); Salmonella typhi STY0319 Rhs-family protein (41.3% evalue=1.E-137) YP_071170.1 similar to Yersinia pestis YPO2724 membrane protein (99.4% evalue=0); Salmonella typhimurium STM0285 inner membrane protein (32% evalue=0) YP_071171.1 similar to Yersinia pestis YPO2723 OmpA family protein (100% evalue=1.E-144); Salmonella typhimurium STM0282 outer membrane protein, OmpA family (41.1% evalue=2.E-83) YP_071172.1 similar to Yersinia pestis YPO2934 conserved hypothetical protein (99.7% evalue=0); Salmonella typhimurium STM0281 cytoplasmic protein (51.6% evalue=1.E-132) YP_071173.1 similar to Yersinia pestis YPO2935 exported protein (100% evalue=1.E-101); Pseudomonas aeruginosa PA0080 hypothetical protein (33.3% evalue=2.E-15) YP_071174.1 similar to Yersinia pestis YPO2937 conserved hypothetical protein (100% evalue=2.E-90); Salmonella typhimurium STM0279 cytoplasmic protein (56.3% evalue=1.E-47) YP_071175.1 similar to Yersinia pestis YPO2938 conserved hypothetical protein (100% evalue=0); Salmonella typhimurium STM0274 cytoplasmic protein (78.8% evalue=0) YP_071176.1 similar to Yersinia pestis YPO2939 conserved hypothetical protein (100% evalue=9.E-92); Salmonella typhimurium STM0273 cytoplasmic protein (77.1% evalue=1.E-68) YP_071177.1 similar to Yersinia pestis YPO2945 frimbrial protein (37.1% evalue=3.E-13) YP_071178.1 similar to Xylella fastidiosa XF0081 outer membrane usher protein precursor (33.8% evalue=1.E-137); Pseudomonas aeruginosa PA4084 probable fimbrial biogenesis usher protein (35.2% evalue=1.E-131) YP_071179.1 similar to Yersinia pestis YPO2944 pili chaperone protein (100% evalue=1.E-140); Escherichia coli Z0151 ecpD; fimbrial chaperone protein (44.4% evalue=1.E-51) YP_071180.1 similar to Yersinia pestis YPO2945 frimbrial protein (98.8% evalue=2.E-96); Xylella fastidiosa XF0083 fimbrial subunit precursor (36.1% evalue=2.E-16) YP_071181.1 similar to Yersinia pestis YPO2946 clpB5; Clp ATPase (99.2% evalue=0); Salmonella typhimurium STM0272 ATPase with chaperone activity; Homolog of Yersinia clpB (60.1% evalue=0) YP_071182.1 similar to Yersinia pestis YPO2947 conserved hypothetical protein (99.8% evalue=0); Salmonella typhimurium STM0268 cytoplasmic protein (55.4% evalue=0) YP_071183.1 similar to Yersinia pestis YPO2948 conserved hypothetical protein (99.7% evalue=0); Salmonella typhimurium STM0267 cytoplasmic protein (45.4% evalue=2.E-78) YP_071184.1 similar to Yersinia pestis YPO2949 hypothetical protein (97.9% evalue=0); Salmonella typhimurium STM0266 cytoplasmic protein (32.2% evalue=3.E-45) YP_071185.1 similar to Yersinia pestis YPO2950 fimbrial protein (96.2% evalue=0) YP_071186.1 similar to Yersinia pestis YPO2951 hypothetical protein (98.4% evalue=0) YP_071187.1 similar to Yersinia pestis YPO2952 membrane protein (95.2% evalue=1.E-122) YP_071188.1 similar to Yersinia pestis YPO2953 membrane protein (97.1% evalue=0) YP_071189.1 similar to Yersinia pestis YPO2954 hypothetical protein (100% evalue=2.E-89) YP_071190.1 similar to Yersinia pestis YPO2955 luxR-family regulatory protein (99% evalue=1.E-107) YP_071191.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_071192.1 similar to Yersinia pestis YPO2958 sfuA, yfuA; iron(III)-binding periplasmic protein (99.7% evalue=0); Mesorhizobium loti mlr3495 iron-binding periplasmic protein; sfuA protein precursor (72.2% evalue=1.E-130) YP_071193.1 similar to Yersinia pestis YPO2959 sfuB, yfuB; iron(III)-transport system permease (99.2% evalue=0); Mesorhizobium loti mlr3497 IRON(III)-TRANSPORT SYSTEM PERMEase SFUB (63.4% evalue=0) YP_071194.1 similar to Yersinia pestis YPO2960 sfuC, yfuC; iron(III)-transport ATP-binding protein (99.7% evalue=0); Mesorhizobium loti mlr3498 IRON(III)-TRANSPORT ATP-BINDING PROTEIN SFUC (50.6% evalue=6.E-89) YP_071195.1 similar to Yersinia pestis YPO2961 membrane protein (100% evalue=1.E-93); Mesorhizobium loti mll8055 hypothetical protein (38.6% evalue=5.E-28) YP_071196.1 similar to Yersinia pestis YPO2962 conserved hypothetical protein (100% evalue=1.E-88) YP_071197.1 similar to Yersinia pestis YPO4049 membrane protein (30.3% evalue=5.E-15) YP_071198.1 similar to Yersinia pestis YPO2965 dmsA; dimethyl sulfoxide reductase chain A protein (99.2% evalue=0); Salmonella typhimurium STM4305 anaerobic dimethyl sulfoxide reductase, subunit A (56.2% evalue=0) YP_071199.1 similar to Yersinia pestis YPO2966 dmsB; dimethyl sulfoxide reductase chain B protein (100% evalue=1.E-125); Salmonella typhimurium STM4306 anaerobic dimethyl sulfoxide reductase, subunit B (67.8% evalue=2.E-87) YP_071200.1 similar to Yersinia pestis YPO2967 dmsC; dimethyl sulfoxide reductase chain C protein (99.6% evalue=1.E-141); Salmonella typhimurium STM4307 anaerobic dimethyl sulfoxide reductase, subunit C (43% evalue=3.E-50) YP_071201.1 similar to Yersinia pestis YPO2968 conserved hypothetical protein (98.9% evalue=1.E-113); Salmonella typhimurium STM4308 component of anaerobic dehydrogenases (48.7% evalue=1.E-46) YP_071202.1 similar to Yersinia pestis YPO2969 iron-sulphur protein (99.4% evalue=1.E-111); Pasteurella multocida PM1758 hypothetical HI1043 (37.9% evalue=6.E-21) YP_071203.1 similar to Yersinia pestis YPO2970 lipoprotein (100% evalue=1.E-119); Ralstonia solanacearum RS01774 probable lipoprotein (62.4% evalue=6.E-68) YP_071204.1 similar to Yersinia pestis YPO2971 lipoprotein (100% evalue=2.E-64); Ralstonia solanacearum RS01775 probable lipoprotein (45.2% evalue=5.E-24) YP_071205.1 similar to Yersinia pestis YPO2972 lipoprotein (97.7% evalue=1.E-119); Neisseria meningitidis NMB1164 hypothetical protein (76.4% evalue=9.E-89) YP_071206.1 similar to Yersinia pestis YPO2973 hypothetical protein (97.2% evalue=8.E-74); Escherichia coli ECs2042 hypothetical protein (27.6% evalue=3.E-10) YP_071207.1 similar to Yersinia pestis YPO2974 B-type cytochrome (100% evalue=1.E-102); Salmonella typhi STY1868 cytochrome (44.7% evalue=1.E-43) YP_071208.1 similar to Yersinia pestis YPO2975 aminotransferase (99.7% evalue=0); Pseudomonas aeruginosa PA4715 N-succinyldiaminopimelate aminotransferase (90.7% evalue=0) YP_071209.1 similar to Yersinia pestis YPO2976 conserved hypothetical protein (99.7% evalue=0); Escherichia coli ECs0898 hypothetical protein (51.2% evalue=1.E-112) YP_071210.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_071211.1 similar to Yersinia pestis YPO2978 membrane protein (98.7% evalue=1.E-85); Salmonella typhimurium STM3021 inner membrane protein (58.1% evalue=2.E-45) YP_071212.1 similar to Yersinia pestis YPO2979 lysR-family transcriptional regulatory protein (100% evalue=1.E-167); Salmonella typhi STY3165 possible regulatory protein (59.7% evalue=9.E-90) YP_071213.1 similar to Yersinia pestis YPO2980 ion channel protein (99.6% evalue=0); Salmonella typhi STY2647 ion-channel protein (74.6% evalue=1.E-142) YP_071214.1 similar to Yersinia pestis YPO2981 exported protein (100% evalue=4.E-86) YP_071215.1 similar to Yersinia pestis YPO2982 mntH; manganese transport protein MntH (100% evalue=0); Escherichia coli Z3658 transport system permease (77.5% evalue=1.E-176) YP_071216.1 similar to Yersinia pestis YPO2983 nupC, cru; nucleoside permease (100% evalue=0); Salmonella typhimurium STM2409 nupC; NUP family, nucleoside transport (81.7% evalue=1.E-176) YP_071217.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_071218.1 similar to Yersinia pestis YPO2986 conserved hypothetical protein (100% evalue=1.E-117); Vibrio cholerae VCA0380 hypothetical protein (41.9% evalue=2.E-35) YP_071219.1 similar to Yersinia pestis YPO2987 exported protein (98.2% evalue=3.E-55); Escherichia coli Z3672 hypothetical protein (37.7% evalue=1.E-11) YP_071220.1 similar to Yersinia pestis YPO2988 conserved hypothetical protein (100% evalue=2.E-35); Salmonella typhimurium STM2426 cytoplasmic protein (78.2% evalue=1.E-24) YP_071221.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_071222.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_071223.1 role in sulfur assimilation YP_071224.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_071225.1 similar to Yersinia pestis YPO2993 ptsH, hpr; PTS system, phosphocarrier protein (100% evalue=8.E-41); Escherichia coli JW2408 ptsH; Phosphocarrier protein Hpr (histidine-containing protein) (97.6% evalue=5.E-40) YP_071226.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_071227.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_071228.1 similar to Yersinia pestis YPO2997 two-component system sensor kinase (99.5% evalue=0); Ralstonia solanacearum RS03089 probable two-component transmembrane sensor kinase transcription regulator protein (37.9% evalue=2.E-49) YP_071229.1 similar to Yersinia pestis YPO2998 two-component system response regulator (100% evalue=1.E-125); Ralstonia solanacearum RS03088 probable two-component response regulator transcription regulator protein (49.7% evalue=1.E-57) YP_071230.1 similar to Yersinia pestis YPO2999 HlyD family secretion protein (100% evalue=0); Agrobacterium tumefaciens Atu5177 efflux protein (45.9% evalue=6.E-89) YP_071231.1 similar to Yersinia pestis YPO3000 ABC transporter, ATP-binding protein (99.8% evalue=0); Agrobacterium tumefaciens Atu5178 ABC transporter, nucleotide binding/ATPase (54.7% evalue=0) YP_071232.1 similar to Yersinia pestis YPO3001 pyridine nucleotide-disulphide oxidoreductase (99% evalue=0); Lactococcus lactis L194050 noxC; NADH oxidase (51.6% evalue=1.E-154) YP_071233.1 similar to Yersinia pestis YPO3002 permease (99.7% evalue=0); Bacillus subtilis BG13069 yhjB; sodium:solute symporter (49.5% evalue=1.E-141) YP_071234.1 similar to Yersinia pestis YPO3033 hypothetical protein YP_071235.1 similar to Yersinia pestis YPO1950 peptidase (70.3% evalue=1.E-162); Agrobacterium tumefaciens AGR_L_3328 hypothetical protein (30.6% evalue=2.E-43) YP_071236.1 similar to Yersinia pestis YPO3006 aminotransferase (99.4% evalue=0); Clostridium acetobutylicum CAC2970 PatB; PLP-dependent aminotransferase, (45.1% evalue=1.E-100) YP_071237.1 similar to Yersinia pestis YPO3007 membrane protein (99.7% evalue=0); Anabaena all1782 hypothetical protein (27.5% evalue=3.E-34) YP_071238.1 similar to Yersinia pestis YPO3008 two-component sensor histidine kinase (100% evalue=0); S. pneumoniae_R6spr1894 phoR pnpS; histidine kinase (33.9% evalue=1.E-31) YP_071239.1 similar to Yersinia pestis YPO3009 two-component response regulator (99.5% evalue=1.E-133); C. perfringens CPE0642 two-component response regulator (42.7% evalue=1.E-49) YP_071240.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_071241.1 similar to Yersinia pestis YPO3012 cysA; sulfate transport ATP-binding protein (99.7% evalue=0); Escherichia coli ECs3293 ATP-binding component of sulfate permease A protein; chromate resistance (77.9% evalue=1.E-161) YP_071242.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_071243.1 similar to Yersinia pestis YPO3014 cysT; sulfate transport system permease CysT (100% evalue=1.E-153); Escherichia coli b2424 cysU, cysT; sulfate transport system permease (85.9% evalue=1.E-133) YP_071244.1 similar to Yersinia pestis YPO3015 cysP; thiosulfate-binding protein (100% evalue=0); Escherichia coli Z3690 cysP; thiosulfate binding protein (74.3% evalue=1.E-146) YP_071245.1 similar to Yersinia pestis YPO3016 nanT; sugar transporter (99.8% evalue=0); Escherichia coli b3224 nanT; sialic acid transporter (76.1% evalue=0) YP_071246.1 similar to Yersinia pestis YPO3017 rpiR-family transcriptional regulatory protein (99.3% evalue=1.E-157); Salmonella typhimurium STM1127 transcriptional regulator (69.7% evalue=1.E-103) YP_071247.1 similar to Yersinia pestis YPO3019 conserved hypothetical protein (98.6% evalue=9.E-84); Pasteurella multocida PM1713 hypothetical HI0227 (52.5% evalue=9.E-33) YP_071248.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein YP_071249.1 similar to Yersinia pestis YPO1007 antigenic leucine-rich repeat protein (36.2% evalue=3.E-47) YP_071250.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_071251.1 similar to Yersinia pestis YPO3024 nanA, npl; probable N-acetylneuraminate lyase (100% evalue=1.E-170); Vibrio cholerae VC1776 N-acetylneuraminate lyase, (75% evalue=1.E-126) YP_071252.1 similar to Yersinia pestis YPO3025 conserved hypothetical protein (99.6% evalue=1.E-172); Salmonella typhi STY2683 conserved hypothetical protein (67.6% evalue=1.E-113) YP_071253.1 similar to Yersinia pestis YPO3026 yfeY; lipoprotein (100% evalue=1.E-115); Escherichia coli JW2425 hypothetical protein (55.4% evalue=4.E-57) YP_071254.1 similar to Yersinia pestis YPO3027 ygiW; exported protein (100% evalue=7.E-75); Salmonella typhi STY3353 possible exported protein (58.8% evalue=1.E-39) YP_071255.1 similar to Yersinia pestis YPO3028 autotransporter (99.4% evalue=0) YP_071256.1 similar to Yersinia pestis YPO3029 membrane protein (99.2% evalue=1.E-71) YP_071257.1 part of possible compound transposon with IS630 YP_071258.1 part of possible compound transposon with IS630 YP_071259.1 part of possible compound transposon with IS630 YP_071260.1 similar to Yersinia pestis YPO3031 acetyltransferase (100% evalue=8.E-80); Salmonella typhimurium STM2449 acetyltransferase (78% evalue=3.E-64) YP_071261.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_071262.1 similar to Yersinia pestis YPO3033 conserved hypothetical protein (100% evalue=7.E-83); Escherichia coli ECs0436 hypothetical protein (76.9% evalue=3.E-59) YP_071263.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_071264.1 similar to Yersinia pestis YPO3035 conserved hypothetical protein (100% evalue=1.E-112); Escherichia coli Z3723 yffH; orf, hypothetical protein (60.7% evalue=1.E-60) YP_071265.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_071266.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_071267.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_071268.1 similar to Yersinia pestis YPO3039 napD; conserved hypothetical protein (100% evalue=2.E-45); Escherichia coli ECs3096 hypothetical protein (55.4% evalue=1.E-19) YP_071269.1 similar to Yersinia pestis YPO3040 napF; ferredoxin-type protein NapF (99.4% evalue=4.E-97); Escherichia coli ECs3097 ferredoxin-type protein (52.8% evalue=6.E-47) YP_071270.1 similar to Yersinia pestis YPO3041 narP; nitrate/nitrite response regulator protein NarP (100% evalue=1.E-113); Salmonella typhimurium STM2246 narP; response regulator in two-component regulatory system with NarQ (or NarX) (68.6% evalue=2.E-71) YP_071271.1 similar to Yersinia pestis YPO3042 conserved hypothetical protein (100% evalue=7.E-50); Vibrio cholerae VC2149 hypothetical protein (58.2% evalue=3.E-27) YP_071272.1 similar to Yersinia pestis YPO3043 multidrug efflux protein (99.9% evalue=0); Salmonella typhi STY2719 acrD; efflux pump (80.6% evalue=0) YP_071273.1 similar to Yersinia pestis YPO3044 hypothetical protein (100% evalue=1.E-112) YP_071274.1 similar to Yersinia pestis YPO3045 ybcI; membrane protein (100% evalue=1.E-102); Salmonella typhimurium STM0540 ybcI; membrane-bound metal-dependent hydrolases (72.6% evalue=5.E-71) YP_071275.1 similar to Yersinia pestis YPO3046 sulfatase modifier protein (99.7% evalue=0); Escherichia coli ECs2102 enzyme (66% evalue=1.E-156) YP_071276.1 similar to Yersinia pestis YPO3047 ydeN; sulfatase (100% evalue=0); Escherichia coli JW1493 hypothetical protein (80% evalue=0) YP_071277.1 similar to Yersinia pestis YPO3048 probable ABC-transporter, ATP-binding protein (99.7% evalue=0); Ralstonia solanacearum RS00150 probable ATP-binding ABC transporter protein (69.4% evalue=1.E-133) YP_071278.1 similar to Yersinia pestis YPO3049 binding protein-dependent transport system, inner-membrane component (99.8% evalue=0); Ralstonia solanacearum RS00151 transmembrane ABC transporter protein (70.2% evalue=0) YP_071279.1 similar to Yersinia pestis YPO3050 exported protein (99.7% evalue=0); Ralstonia solanacearum RS00344 periplasmic iron-binding signal peptide protein (62.1% evalue=1.E-125) YP_071280.1 similar to Yersinia pestis YPO3051 conserved hypothetical protein (100% evalue=4.E-83); Listeria innocua lin0965 lin0965 (38.6% evalue=4.E-22) YP_071281.1 similar to Yersinia pestis YPO3052 conserved hypothetical protein (100% evalue=3.E-74); Escherichia coli ECs3333 hypothetical protein (69.9% evalue=8.E-40) YP_071282.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_071283.1 similar to Yersinia pestis YPO3054 carboxypeptidase (100% evalue=1.E-132); Pasteurella multocida PM1021 hypothetical HI0101 (48.8% evalue=8.E-58) YP_071284.2 similar to Yersinia pestis YPO3055 membrane protein (100% evalue=3.E-35); Salmonella typhi STY2722 membrane protein (69.6% evalue=1.E-22) YP_071285.1 similar to Yersinia pestis YPO3056 acetyltransferase (99.2% evalue=0); Escherichia coli Z3733 ypfI; orf, hypothetical protein (52.3% evalue=0) YP_071286.1 similar to Yersinia pestis YPO3057 yeaL; membrane protein (100% evalue=9.E-77); Salmonella typhi STY1838 membrane protein (72.4% evalue=7.E-58) YP_071287.1 similar to Yersinia pestis YPO3058 membrane protein (99.6% evalue=1.E-167); Salmonella typhimurium STM2486 inner membrane protein (76.4% evalue=1.E-125) YP_071288.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_071289.1 similar to Yersinia pestis YPO3061 dapX, nlpB; lipoprotein (99.7% evalue=0); Salmonella typhimurium STM2488 nlpB; lipoprotein-34 (62% evalue=1.E-120) YP_071290.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_071291.2 negative transcriptional regulator of the gcvTHP operon YP_071292.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_071293.1 similar to Yersinia pestis YPO3065 exported protein, 100% identical YP_071294.1 similar to Yersinia pestis YPO3066 hypothetical protein (99.1% evalue=1.E-133) YP_071295.1 similar to Yersinia pestis YPO3067 hypothetical protein, 100% identical. YP_071296.1 similar to Yersinia pestis YPO3068 perM; membrane protein (100% evalue=0); Salmonella typhimurium STM2493 perM; PerM family permease (77.6% evalue=1.E-161) YP_071297.1 similar to Yersinia pestis YPO3069 exported protein (99.3% evalue=0); Escherichia coli b2494 hypothetical protein (69.3% evalue=0) YP_071298.1 similar to Yersinia pestis YPO3070 yfgD; arsenate reductase (100% evalue=8.E-62); Escherichia coli ECs3357 oxidoreductase (67.2% evalue=4.E-40) YP_071299.2 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_071300.1 similar to Escherichia coli ECs3359 uracil transport (89.3% evalue=0); Escherichia coli Z3760 uraA; uracil transport (89.3% evalue=0) YP_071301.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_071302.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_071303.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_071304.1 similar to Yersinia pestis YPO2830 speG; spermidine acetyltransferase (100% evalue=1.E-102); Escherichia coli JW1576 speG; diamine N-acetyltransferase (80.1% evalue=5.E-80) YP_071305.1 similar to Salmonella typhimurium STM1958 fliB; N-methylation of lysine residues in flagellin (30% evalue=1.E-52); C. perfringens CPE0799 hypothetical protein (23.4% evalue=3.E-14) YP_071306.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_071307.1 similar to Yersinia pestis YPO2834 pstA; phosphate transport system permease (99.8% evalue=0); Vibrio cholerae VC0725 phosphate transport system permease (52.7% evalue=1.E-158) YP_071308.1 similar to Yersinia pestis YPO2835 pstC; phosphate transport system permease (99.5% evalue=0); Pseudomonas aeruginosa PA5368 pstC; phosphate transport system permease (42.2% evalue=1.E-137) YP_071309.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_071310.1 similar to Yersinia pestis YPO2837 ppx; exopolyphosphatase (100% evalue=0); Salmonella typhi STY2743 ppx; exopolyphosphatase (77.3% evalue=0) YP_071311.1 similar to Yersinia pestis YPO2838 yfgG; exported protein (98.5% evalue=9.E-33) YP_071312.1 similar to Yersinia pestis YPO2839 mgtE; divalent cation transport protein (100% evalue=0); Pseudomonas aeruginosa PA0913 mgtE; probable Mg transporter MgtE (54.3% evalue=1.E-139) YP_071313.1 similar to Yersinia pestis YPO2840 heat shock protein (99.5% evalue=0); Escherichia coli ECs2878 heat shock protein (72.4% evalue=0) YP_071314.1 similar to Yersinia pestis YPO2841 ABC transporter permease (100% evalue=1.E-154); Pseudomonas aeruginosa PA0606 spermidine/putrescine transport system permease (65.3% evalue=8.E-91) YP_071315.1 similar to Yersinia pestis YPO2842 ABC transporter permease (99.7% evalue=0); Pseudomonas aeruginosa PA0605 spermidine/putrescine transport system permease (54.5% evalue=1.E-121) YP_071316.1 similar to Yersinia pestis YPO2843 transport system periplasmic protein (99.4% evalue=0); Pseudomonas aeruginosa PA0222 spermidine/putrescine transport system substrate-binding protein (56.1% evalue=1.E-116) YP_071317.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_071318.1 similar to Yersinia pestis YPO2845 GntR-family regulatory protein (99.6% evalue=0); Ralstonia solanacearum RS01853 transcription regulator protein (47% evalue=1.E-124) YP_071319.1 similar to Yersinia pestis YPO2846 putitive ABC-transporter ATP-binding protein (99.7% evalue=0); Pseudomonas aeruginosa PA0603 spermidine/putrescine transport system ATP-binding protein (60.7% evalue=1.E-119) YP_071320.2 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_071321.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_071322.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_071323.1 similar to Yersinia pestis YPO2850 yegB; membrane protein (99.7% evalue=0); Escherichia coli JW2062 yegB; Hypothetical protein (72.3% evalue=0) YP_071324.1 similar to Salmonella typhi STY2343 baeS; two-component system sensor kinase (66.8% evalue=1.E-171); Salmonella typhimurium STM2130 baeS; sensory kinase in two-component regulatoyr system wtih BaeR (67.2% evalue=1.E-173) YP_071325.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_071326.1 similar to Yersinia pestis YPO2854 conserved hypothetical protein (100% evalue=4.E-58); Pasteurella multocida PM0519 hypothetical Escherichia coli (61.2% evalue=2.E-32) YP_071327.1 similar to Yersinia pestis YPO2855 protease (100% evalue=0); Escherichia coli JW2066 yegQ; protease (83.4% evalue=0) YP_071328.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_071329.1 similar to Yersinia pestis YPO2857 exported protein (99.3% evalue=5.E-89); Pseudomonas aeruginosa PA3902 hypothetical protein (42.8% evalue=3.E-30) YP_071330.1 similar to Yersinia pestis YPO2858 hypothetical protein (97.9% evalue=1.E-140) YP_071331.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_071332.1 similar to Yersinia pestis YPO3895 membrane protein (52.8% evalue=1.E-48) YP_071333.1 similar to Yersinia pestis YPO4106 hypothetical protein (54.1% evalue=8.E-55) YP_071334.1 similar to Yersinia pestis YPO2864 membrane protein, 100% identical. YP_071335.1 similar to Yersinia pestis YPO2865 membrane protein, 93% identical YP_071336.1 similar to Yersinia pestis YPO2866 membrane protein (73.3% evalue=1.E-54) YP_071337.1 similar to Yersinia pestis YPO2868 conserved hypothetical protein, 92% identical. YP_071338.1 similar to Yersinia pestis YPO2868 conserved hypothetical protein, 99% identical YP_071339.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_071340.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_071341.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_071342.1 similar to Yersinia pestis YPO2873 conserved hypothetical protein (97.2% evalue=1.E-41); Salmonella typhi STY2763a conserved hypothetical protein (61.7% evalue=2.E-21) YP_071343.1 similar to Yersinia pestis YPO2874 membrane protein (99.3% evalue=1.E-174); Vibrio cholerae VCA0024 conserved hypothetical protein (43.4% evalue=3.E-67) YP_071344.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_071345.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_071346.1 similar to Yersinia pestis YPO2877 yfgM; membrane protein (99.5% evalue=1.E-112); Salmonella typhimurium STM2521 yfgM; inner membrane protein (58.5% evalue=1.E-64) YP_071347.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_071348.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_071349.1 similar to Yersinia pestis YPO2880 yfgA; DNA-binding protein (92.8% evalue=0); Salmonella typhimurium STM2524 yfgA; paral membrane protein (57.9% evalue=1.E-106) YP_071350.1 similar to Yersinia pestis YPO2881 fimbrial biogenesis protein (99.5% evalue=1.E-139); Vibrio cholerae VC1612 fimbrial biogenesis and twitching motility protein, (37.1% evalue=2.E-30) YP_071351.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_071352.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_071353.1 similar to Yersinia pestis YPO2884 exported protein (94.9% evalue=0) YP_071354.1 similar to Yersinia pestis YPO2885 hypothetical protein (96.4% evalue=5.E-41) YP_071355.1 similar to Yersinia pestis YPO2886 yapA; autotransporter protein (79% evalue=0); Escherichia coli JW2628 ypjA; Hypothetical protein (f949) (27.1% evalue=8.E-79) YP_071356.1 similar to Yersinia pestis YPO2886 yapA; autotransporter protein (43.2% evalue=0) YP_071357.1 similar to Yersinia pestis YPO2886 yapA; autotransporter protein (38.8% evalue=0); Escherichia coli Z3449 yejO; ATP-binding component of a transport system (26.9% evalue=1.E-68) YP_071358.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_071359.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_071360.1 similar to Yersinia pestis YPO2890 conserved hypothetical protein (100% evalue=2.E-34); Escherichia coli JW2508 yfhJ; Hypothetical protein (77.2% evalue=3.E-26) YP_071361.1 similar to Yersinia pestis YPO2891 fdx; adrenodoxin family ferredoxin (100% evalue=3.E-62); Escherichia coli JW2509 fdx; Ferredoxin [2Fe-2S] (91.8% evalue=3.E-57) YP_071362.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_071363.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_071364.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_071365.1 similar to Yersinia pestis YPO2895 nifU; NifU family protein (99.2% evalue=2.E-68); Escherichia coli Z3796 hypothetical protein (89% evalue=1.E-61) YP_071366.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_071367.1 regulates the expression of the iscRSUA operon YP_071368.1 similar to Yersinia pestis YPO2898 SpoU-family rRNA methylase (100% evalue=1.E-144); Salmonella typhi STY2791 RNA methyltransferase (81.8% evalue=1.E-109) YP_071369.1 similar to Yersinia pestis YPO2899 suhB; myo-inositol-1(or 4)-monophosphatase (100% evalue=1.E-151); Escherichia coli b2533 suhB, ssyA; myo-inositol-1(or 4)-monophosphatase (83.8% evalue=1.E-129) YP_071370.1 similar to Yersinia pestis YPO2901 membrane protein (99.7% evalue=0); Salmonella typhimurium STM2551 inner membrane protein (55% evalue=7.E-98) YP_071371.1 similar to Yersinia pestis YPO2902 exported protein (99.5% evalue=1.E-125); Salmonella typhimurium STM2552 periplasmic or exported protein (55.3% evalue=2.E-62) YP_071372.1 similar to Yersinia pestis YPO2903 RNA-binding protein (100% evalue=0); Escherichia coli b2535 csiE; stationary phase inducible protein csiE (37.4% evalue=5.E-81) YP_071373.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_071374.1 similar to Yersinia pestis YPO2905 ail; attachment invasion locus protein (99.4% evalue=1.E-101) YP_071375.1 similar to Yersinia pestis YPO2906 membrane protein, 100% identical YP_071376.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_071377.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_071378.1 similar to Escherichia coli b3383 yhfZ; hypothetical 25.4 kD protein in cysG-trpS intergenic region (F228) (52.4% evalue=1.E-62); Escherichia coli JW3346 yhfZ; Hypothetical protein (52.4% evalue=1.E-62) YP_071379.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_071380.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_071381.1 similar to Yersinia pestis YPO2914 two-component system response regulator (100% evalue=0); Salmonella typhimurium STM2562 yfhA; transcriptional regulator of two-component regulator protein (EBP familiiy) (87.1% evalue=0) YP_071382.1 similar to Yersinia pestis YPO2915 lipoprotein (94.7% evalue=0); Escherichia coli JW2539 yfhG; Hypothetical protein (ORF-1) (46.1% evalue=8.E-45) YP_071383.1 similar to Yersinia pestis YPO2916 two-component system sensor kinase (99.7% evalue=0); Salmonella typhimurium STM2564 yfhK; sensory kinase in regulatory system (72.4% evalue=0) YP_071384.1 similar to Yersinia pestis YPO2919 hypothetical protein (26.9% evalue=7.E-08) YP_071385.1 similar to Yersinia pestis YPO2919 hypothetical protein (99.4% evalue=1.E-106) YP_071386.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_071387.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_071388.1 similar to Yersinia pestis YPO2923 zinc-binding protein (99.3% evalue=8.E-86); Escherichia coli b2559 yfhC; hypothetical 20.0 kD protein in purL-dpj intergenic region (ORF178) (71% evalue=6.E-65) YP_071389.1 similar to Yersinia pestis YPO2924 yfhB; membrane protein (99.5% evalue=1.E-122); Salmonella typhimurium STM2569 yfhB; putatative phosphoserine phosphatase (69.4% evalue=9.E-80) YP_071390.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_071391.1 similar to Yersinia pestis YPO2926 RpiR-family transcriptional regulatory protein (100% evalue=1.E-148); Salmonella typhimurium STM2572 yfhH; ABC superfamily (membrane) transport protein (62.4% evalue=2.E-93) YP_071392.1 similar to Yersinia pestis YPO2927 fdx; [4Fe-4S] ferredoxin (100% evalue=3.E-49); Salmonella typhi STY2822 ferredoxin (80.2% evalue=4.E-38) YP_071393.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_071394.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_071395.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_071396.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_071397.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_071398.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_071399.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_071400.1 similar to Yersinia pestis YPO2715 membrane protein (94.4% evalue=1.E-133) YP_071401.1 involved in the reduction of the SoxR iron-sulfur cluster YP_071402.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_071403.1 similar to Yersinia pestis YPO2712 rseA, mclA; sigma E factor negative regulatory protein (100% evalue=1.E-122); Escherichia coli JW2556 rseA; Sigma-E (sigma-24) factor negative regulatory protein (63.3% evalue=2.E-75) YP_071404.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_071405.1 catalyzes the formation of oxaloacetate from L-aspartate YP_071406.1 similar to Yersinia pestis YPO2709 conserved hypothetical protein (99.6% evalue=1.E-146); Escherichia coli ECs3441 enzyme (53.1% evalue=3.E-67) YP_071407.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_071408.1 similar to Yersinia pestis YPO2707 yplB; phospholipase A accessory protein (100% evalue=1.E-122); C. elegans B0350.2B unc-44; (CE06703) (31.3% evalue=3.E-07) YP_071409.1 similar to Yersinia pestis YPO2706 yplA, plaA; phospholipase A (100% evalue=1.E-179) YP_071410.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_071411.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_071412.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_071413.1 similar to Yersinia pestis YPO2702 membrane protein (99.7% evalue=0); Ralstonia solanacearum RS01432 probable transmembrane protein (56% evalue=1.E-101) YP_071414.1 similar to Yersinia pestis YPO2701 membrane protein (99.5% evalue=1.E-132); Ralstonia solanacearum RS01431 probable transmembrane protein (69.1% evalue=8.E-88) YP_071415.1 similar to Yersinia pestis YPO2700 conserved hypothetical protein (99.5% evalue=1.E-136); Escherichia coli JW0703 ybgL; Hypothetical protein (71.3% evalue=3.E-93) YP_071416.1 similar to Yersinia pestis YPO2699 conserved hypothetical protein (100% evalue=0); Escherichia coli JW0702 ybgK; Hypothetical protein (68.9% evalue=1.E-124) YP_071417.1 similar to Escherichia coli ECs0736 carboxylase (71.5% evalue=1.E-89); Escherichia coli JW0701 ybgJ, ybgK; Hypothetical protein (72% evalue=6.E-90) YP_071418.1 similar to Yersinia pestis YPO2697 conserved hypothetical protein (99.5% evalue=1.E-141); Escherichia coli ECs0735 hypothetical protein (69.2% evalue=6.E-97) YP_071419.1 similar to Yersinia pestis YPO2696 3',5'-cyclic-nucleotide phosphodiesterase (99.7% evalue=0); S. pombe CGS2 cgs2, spcc285.09c, pde1; 3',5'-cyclic-nucleotide phosphodiesterase (27.4% evalue=2.E-25) YP_071420.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_071421.1 similar to Yersinia pestis YPO2694 conserved hypothetical protein (100% evalue=7.E-90); Escherichia coli ECs0732 hypothetical protein (54.5% evalue=3.E-41) YP_071422.1 similar to Yersinia pestis YPO2693 ybfA; membrane protein (100% evalue=8.E-34); Salmonella typhimurium STM0708 ybfA; periplasmic protein (63.2% evalue=1.E-20) YP_071423.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_071424.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_071425.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_071426.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_071427.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_071428.1 similar to Yersinia pestis YPO2687 membrane protein (100% evalue=1.E-70); P. abyssi PAB0665 hypothetical protein (51.7% evalue=9.E-33) YP_071430.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_071431.1 negative modulator of the initiation of chromosome replication YP_071432.1 similar to Yersinia pestis YPO2684 exported protein (99.1% evalue=5.E-63) YP_071433.1 similar to Yersinia pestis YPO2683 hypothetical protein, 100% identical. YP_071434.1 similar to Yersinia pestis YPO2682 conserved hypothetical protein (100% evalue=1.E-147); Escherichia coli Z2763 ydjC; orf, hypothetical protein (60.7% evalue=7.E-85) YP_071435.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_071436.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_071437.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_071438.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_071439.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_071440.1 similar to Yersinia pestis YPO2675 potassium channel protein (98.9% evalue=0); Escherichia coli ECs1750 potassium channel protein (37.8% evalue=2.E-65) YP_071441.1 similar to Yersinia pestis YPO2674 exported protein (100% evalue=1.E-58); Salmonella typhimurium STM1562 periplasmic transport protein (44.4% evalue=2.E-21) YP_071442.1 similar to Yersinia pestis YPO2673 nickel transport protein (99.4% evalue=0); Salmonella typhimurium STM2783 nxiA; nickel transporter (60.1% evalue=1.E-119) YP_071443.1 similar to Yersinia pestis YPO2672 urea transporter (99% evalue=0); Brucella melitensis BMEI0642 ureA transporter (45.7% evalue=9.E-76) YP_071444.1 similar to Brucella melitensis BMEI0643 urease accessory protein UreD (51.8% evalue=5.E-89); B. halodurans BH0258 ureD; urease accessory protein (29.6% evalue=3.E-14) YP_071445.1 similar to Yersinia pestis YPO2670 ureG; urease accessory protein (99.5% evalue=1.E-120); Brucella melitensis BMEI0644 urease accessory protein UreG (71.2% evalue=2.E-84) YP_071446.1 similar to Yersinia pestis YPO2669 ureF; urease accessory protein (99.5% evalue=1.E-126); Brucella melitensis BMEI0645 urease accessory protein UreF (51.3% evalue=8.E-56) YP_071447.1 involved in the assembly of the urease metallocenter; possible nickel donor YP_071448.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_071449.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta) YP_071450.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_071451.1 similar to Yersinia pestis YPO2664 transport ATPase (100% evalue=1.E-126); Salmonella typhimurium STM1259 ATPase component of ABC-type transport system, contain duplicated ATPase domain (61.7% evalue=8.E-66) YP_071452.1 similar to Yersinia pestis YPO2663 transport ATPase (99.6% evalue=1.E-153); Salmonella typhimurium STM1258 ATPase component of ABC-type transport system, contain duplicated ATPase domain (51.3% evalue=1.E-67) YP_071453.1 similar to Yersinia pestis YPO2662 binding-protein-dependent transport protein (100% evalue=1.E-153); Salmonella typhi STY1863 inner membrane transport protein (61.6% evalue=1.E-97) YP_071454.1 similar to Yersinia pestis YPO2661 membrane protein (99.6% evalue=0); Salmonella typhi STY1864 inner membrane transport protein (69.8% evalue=1.E-128) YP_071455.1 similar to Yersinia pestis YPO2660 solute-binding protein (99.6% evalue=0); Salmonella typhimurium STM1255 ABC transporter periplasmic binding protein (72.3% evalue=0) YP_071456.1 similar to Yersinia pestis YPO3644 cspa1; major cold shock protein Cspa1 (91.4% evalue=3.E-32) YP_071458.1 similar to Yersinia pestis YPO2654 yicN; membrane protein (100% evalue=8.E-81); Salmonella typhi STY3996 yicN; exported protein (35.1% evalue=9.E-21) YP_071459.1 similar to Yersinia pestis YPO2653 conserved hypothetical protein (100% evalue=1.E-59); Salmonella typhi STY2924 ygaC; conserved hypothetical protein (59% evalue=2.E-30) YP_071460.1 required for growth and survival under moderately acid conditions YP_071461.1 similar to Yersinia pestis YPO2651 nrdH; glutaredoxin (100% evalue=3.E-40); Agrobacterium tumefaciens AGR_C_102 nrdH; glutaredoxin (61.1% evalue=1.E-23) YP_071462.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_071463.1 Catalyzes the rate-limiting step in dNTP synthesis YP_071464.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_071465.1 similar to Yersinia pestis YPO2647 proV; glycine betaine/L-proline transport ATP-binding protein (100% evalue=0); Escherichia coli JW2652 proV; Glycine betaine/l-proline transport ATP-binding protein ProV (81.6% evalue=0) YP_071466.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_071467.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_071468.1 similar to Ralstonia solanacearum RS01484 conserved hypothetical protein (66.5% evalue=1.E-130); Pseudomonas aeruginosa PA1517 conserved hypothetical protein (58.9% evalue=1.E-110) YP_071469.1 similar to Yersinia pestis YPO1083 permease (99.7% evalue=0); Pseudomonas aeruginosa PA0476 probable permease (38.5% evalue=1.E-100) YP_071470.1 3'-5' exonuclease of DNA polymerase III YP_071471.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_071472.1 similar to Yersinia pestis YPO1080 conserved hypothetical protein (100% evalue=1.E-141); Salmonella typhimurium STM0262 yafS; SAM-dependent methyltransferase (65.2% evalue=8.E-91) YP_071473.1 similar to Yersinia pestis YPO1079 gloB; hydroxyacylglutathione hydrolase (99.6% evalue=1.E-145); Salmonella typhimurium STM0261 gloB; hydroxyacylglutathione hydrolase (58.9% evalue=8.E-86) YP_071474.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_071475.1 similar to Yersinia pestis YPO1077 conserved hypothetical protein (100% evalue=1.E-144); Escherichia coli ECs0205 hypothetical protein (75.1% evalue=1.E-107) YP_071476.1 similar to Yersinia pestis YPO1076 hypothetical protein, 100% identical YP_071477.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_071478.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_071479.1 part of the metNIQ transport system for methionine YP_071480.1 part of the MetNIQ methionine uptake system YP_071481.1 similar to Yersinia pestis YPO1071 lipoprotein (99.2% evalue=1.E-149); Escherichia coli b0197 yaeC; unknown ABC transport system substrate-binding protein (90.4% evalue=1.E-138) YP_071482.1 similar to Yersinia pestis YPO1070 rcsF; lipoprotein (100% evalue=1.E-73); Salmonella typhimurium STM0244 rcsF; regulator in colanic acid synthesis; overexpression confers mucoid phenotype, increases capsule synthesis (67.4% evalue=9.E-46) YP_071483.1 similar to Yersinia pestis YPO1069 conserved hypothetical protein (100% evalue=1.E-135); Salmonella typhimurium STM0243 yaeB; paral regulator (70.2% evalue=7.E-94) YP_071484.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_071485.1 similar to Yersinia pestis YPO1067 cutF, nlpE; copper homeostasis lipoprotein (100% evalue=1.E-130); Escherichia coli ECs0194 copper homeostasis protein (49.1% evalue=2.E-59) YP_071486.1 similar to Yersinia pestis YPO1066 conserved hypothetical protein (99.2% evalue=2.E-69); Escherichia coli b0191 yaeJ; hypothetical 15.6 kD protein in mesJ-cutF intergenic region (ORF140) (65.1% evalue=3.E-47) YP_071487.1 similar to Yersinia pestis YPO1065 conserved hypothetical protein (100% evalue=1.E-103); Escherichia coli b0190 yaeQ; hypothetical 20.9 kD protein in mesJ-cutF intergenic region (61.7% evalue=3.E-64) YP_071488.1 similar to Yersinia pestis YPO1064a conserved hypothetical protein (98.4% evalue=6.E-31); Salmonella typhimurium STM0238 yaeP; cytoplasmic protein (78.7% evalue=8.E-23) YP_071489.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_071490.1 similar to Yersinia pestis YPO1063 cytochrome (100% evalue=1.E-54); Vibrio cholerae VC2241 cytochrome c554 (50.4% evalue=7.E-21) YP_071491.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_071492.1 similar to Yersinia pestis YPO1061 conserved hypothetical protein (99.2% evalue=5.E-73); Escherichia coli ECs0189 hypothetical protein (71.8% evalue=4.E-51) YP_071493.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_071494.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_071495.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_071496.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_071497.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_071498.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_071499.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_071500.1 similar to Yersinia pestis YPO1053 ompH; cationic 19 kDa outer membrane protein precursor (99.3% evalue=9.E-85); Escherichia coli JW0173 hlpA; Histone-like protein hlp-1 precursor (DNA-binding 17 kd protein) (67.6% evalue=1.E-49) YP_071501.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_071502.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_071503.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_071504.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_071505.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_071506.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_071507.1 Catalyzes the phosphorylation of UMP to UDP YP_071508.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_071509.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_071510.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_071511.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_071512.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_071513.1 similar to Yersinia pestis YPO1040 conserved hypothetical protein (100% evalue=2.E-69); Escherichia coli Z0175 yaeH; structural protein (85.7% evalue=3.E-59) YP_071514.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_071515.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_071516.1 similar to Yersinia pestis YPO1037 conserved hypothetical protein (100% evalue=7.E-60); H. influenzae HI1436 hypothetical prltein HI1436 (50.9% evalue=2.E-24) YP_071517.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_071518.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_071519.1 similar to Yersinia pestis YPO1033 conserved hypothetical protein (99.5% evalue=0); Salmonella typhimurium STM2969 ygdH; nucleotide binding (83.9% evalue=0) YP_071520.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_071521.1 similar to Yersinia pestis YPO1031 conserved hypothetical protein (100% evalue=0); Escherichia coli b2806 ygdE; hypothetical 41.9 kD protein in fucR-gcvA intergenic region (ORF3) (78% evalue=1.E-170) YP_071522.1 similar to Yersinia pestis YPO1030 conserved hypothetical protein (100% evalue=2.E-71); Escherichia coli b2807 ygdD; hypothetical 14.3 kD protein in fucR-gcvA intergenic region (ORF2) (71.7% evalue=8.E-53) YP_071523.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_071524.1 similar to Yersinia pestis YPO1028 aminotransferase class V (99.7% evalue=0); Escherichia coli b2810 cysteine sulfinate desulfinase (66.8% evalue=1.E-155) YP_071525.1 similar to Yersinia pestis YPO1027 conserved hypothetical protein (100% evalue=3.E-81); Escherichia coli b2811 ygdK; hypothetical 15.9 kD protein in gcvA-metZ intergenic region (O147) (58.9% evalue=7.E-40) YP_071526.1 similar to Yersinia pestis YPO1026 conserved hypothetical protein (100% evalue=1.E-154); Escherichia coli b2812 ygdL; hypothetical 28.6 kD protein in gcvA-mltA intergenic region (80.5% evalue=1.E-124) YP_071527.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_071528.1 similar to Yersinia pestis YPO1023 N-acetylmuramoyl-L-alanine amidase AmiC precursor (100% evalue=0); Salmonella typhi STY3129 N-acetylmuramoyl-L-alanine amidase (72.3% evalue=1.E-171) YP_071529.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_071530.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_071531.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_071532.1 similar to Yersinia pestis YPO1019 ptrA, ptr; protease III precursor (100% evalue=0); Salmonella typhimurium STM2995 ptr; protease III (63.3% evalue=0) YP_071533.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_071534.1 similar to Yersinia pestis YPO1017 prepilin peptidase dependent protein (100% evalue=2.E-68) YP_071535.1 similar to Yersinia pestis YPO1016 membrane protein (100% evalue=5.E-89) YP_071536.1 similar to Yersinia pestis YPO1015 prepilin peptidase dependent protein (100% evalue=1.E-116); Salmonella typhi STY3137 ppdB; prepilin peptidase dependent protein B precursor (35.1% evalue=7.E-25) YP_071537.1 similar to Yersinia pestis YPO1014a prepilin peptidase (partial) (100% evalue=6.E-26); Salmonella typhimurium STM3000 ppdA; prepilin peptidase dependent protein A, component in type IV pilin biogenesis (35% evalue=5.E-20) YP_071539.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_071540.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_071541.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_071542.1 hydrolyzes diadenosine polyphosphate YP_071543.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_071544.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_071545.1 similar to Yersinia pestis YPO0791 hypothetical protein, 100% identical YP_071546.1 similar to Yersinia pestis YPO0792 ygeD; membrane protein (100% evalue=0); Salmonella typhimurium STM3009 ygeD; efflux protein, resistance protein (76% evalue=1.E-173) YP_071547.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_071548.1 similar to Yersinia pestis YPO0794 bisC; biotin sulfoxide reductas2 (99.6% evalue=0); Mycobacterium tuberculosis Rv1442 bisC; biotin sulfoxide reductase (42.4% evalue=1.E-174) YP_071549.1 controls transcription of galETKM YP_071550.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_071551.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_071552.1 similar to Yersinia pestis YPO0798 sugar transport protein (100% evalue=0); Pseudomonas aeruginosa PA4355 probable MFS transporter (70.2% evalue=1.E-148) YP_071553.1 similar to Yersinia pestis YPO0799 LysR-family transcriptional regulatory protein (99.6% evalue=1.E-168); Pseudomonas aeruginosa PA0056 probable transcriptional regulator (58.2% evalue=5.E-95) YP_071554.1 similar to Yersinia pestis YPO0800 exported protein (100% evalue=1.E-165); Pseudomonas aeruginosa PA0057 hypothetical protein (57.9% evalue=2.E-96) YP_071555.1 similar to Yersinia pestis YPO0801 conserved hypothetical protein (99.5% evalue=1.E-121); Ralstonia solanacearum RS03863 conserved hypothetical protein (59% evalue=5.E-67) YP_071556.1 similar to Yersinia pestis YPO0802 cheD, tse; methyl-accepting chemotaxis protein (99.6% evalue=0); Escherichia coli b4355 tsr, cheD; methyl-accepting chemotaxis protein I (MCP-I) (serine chemoreceptor protein) (40.1% evalue=1.E-101) YP_071557.1 similar to Yersinia pestis YPO0803 hypothetical protein (98.4% evalue=7.E-73) YP_071558.1 similar to Yersinia pestis YPO0804 regulatory membrane protein (100% evalue=1.E-112); Vibrio cholerae VC0826 toxin co-regulated pilus biosynthesis protein P (36.3% evalue=1.E-08) YP_071559.1 similar to Yersinia pestis YPO0805 lipoprotein YP_071560.1 deleted EC_number 3.4.99.-; similar to Yersinia pestis YPO0806 prepilin peptidase (99.6% evalue=1.E-160); Ralstonia solanacearum RS00278 pilD, RSc2827; probable type 4 prepilin peptidase bifunctionnal: leader peptidase and N-methyltransferase transmembrane protein (44% evalue=1.E-53) YP_071561.1 similar to Yersinia pestis YPO0807 membrane protein, 100% identical YP_071562.1 similar to Yersinia pestis YPO0808 general secretion pathway protein L (99.7% evalue=0); Vibrio cholerae VC2725 general secretion pathway protein L (19.5% evalue=4.E-09) YP_071563.1 similar to Yersinia pestis YPO0809 general secretion pathway protein K (93.3% evalue=1.E-170) YP_071564.1 similar to Yersinia pestis YPO0810 general secretion pathway protein J (91.4% evalue=1.E-101); Vibrio cholerae VC2727 general secretion pathway protein J (27.7% evalue=6.E-16) YP_071565.1 similar to Yersinia pestis YPO0811 general secretion pathway protein I (92.1% evalue=5.E-56); Vibrio cholerae VC2728 general secretion pathway protein I (31.9% evalue=6.E-11) YP_071566.1 similar to Yersinia pestis YPO0812 general secretion pathway protein H (98.8% evalue=1.E-101) YP_071567.1 similar to Yersinia pestis YPO0813 general secretion pathway protein G (100% evalue=4.E-80); Escherichia coli b3328 hofG, hopG; general secretion pathway protein G precursor (protein transport protein hofG) (63.9% evalue=2.E-46) YP_071568.1 similar to Escherichia coli b3327 hofF, hopF; general secretion pathway protein F (protein transport protein hofF) (38.8% evalue=5.E-76); Escherichia coli JW3289 hofF (38.8% evalue=5.E-76) YP_071569.1 similar to Yersinia pestis YPO0815 general secretion pathway protein E (100% evalue=0); Vibrio cholerae VC2732 general secretion pathway protein E (56.7% evalue=1.E-142) YP_071570.1 similar to Yersinia pestis YPO0816 general secretion pathway protein D (99.6% evalue=0); Escherichia coli b3325 yheF; general secretion pathway protein D precursor (44.8% evalue=1.E-146) YP_071571.1 similar to Yersinia pestis YPO0817 general secretion pathway protein C (98.8% evalue=4.E-90) YP_071572.1 similar to Yersinia pestis YPO0818 hypothetical protein (100% evalue=4.E-77) YP_071573.1 similar to Yersinia pestis YPO0819 carbonic anhydrase (100% evalue=1.E-138); Salmonella typhimurium PSLT046 carbonic anhydrase (61.3% evalue=7.E-82) YP_071574.1 similar to Yersinia pestis YPO0820 hypothetical protein (95.6% evalue=5.E-48) YP_071575.1 similar to Yersinia pestis YPO0821 hypothetical protein, 98% identical YP_071576.1 similar to Yersinia pestis YPO0822 exported protein (100% evalue=0) YP_071577.1 similar to Yersinia pestis YPO0823 exported protein (100% evalue=0); Rickettsia conorii RC1085 rompB; outer membrane protein B (cell surface antigen sca5) (21.9% evalue=9.E-12) YP_071578.1 similar to Yersinia pestis YPO0824 exported protein (99.9% evalue=0) YP_071579.1 similar to Yersinia pestis YPO0829 sulfatase (99.8% evalue=0); Salmonella typhimurium STM0035 arylsulfatase (24.3% evalue=2.E-26) YP_071580.1 similar to Yersinia pestis YPO0831 DeoR-family regulatory protein (99.6% evalue=1.E-138); Escherichia coli JW3100 agaR; aga operon transcriptional repressor (46.6% evalue=8.E-58) YP_071581.1 similar to Yersinia pestis YPO0832 agaZ; tagatose 6-phosphate kinase (99.7% evalue=0); Escherichia coli b3132 agaZ; tagatose 6-phosphate kinase agaZ (63.5% evalue=1.E-153) YP_071582.1 similar to Yersinia pestis YPO0833 phosphosugar isomerase (99.7% evalue=0); Escherichia coli b3136 agaS; agaS protein (48.6% evalue=2.E-96) YP_071583.1 similar to Yersinia pestis YPO0834 manX; PTS system, N-acetylgalactosamine-specific II component (100% evalue=8.E-92); Escherichia coli Z4485 agaV; PTS system, cytoplasmic, N-acetylgalactosamine-specific IIB component 2 (EIIB-AGA) (48.7% evalue=8.E-38) YP_071584.1 similar to Yersinia pestis YPO0835 PTS permease (100% evalue=1.E-147); Escherichia coli ECs4012 N-acetylgalactosamine-specific PTS system enzyme IIC component (44.2% evalue=1.E-56) YP_071585.1 similar to Yersinia pestis YPO0836 PTS permease (100% evalue=1.E-166); Escherichia coli ECs4013 N-acetylgalactosamine-specific PTS system enzyme IID component (43.9% evalue=2.E-55) YP_071586.1 similar to Yersinia pestis YPO0837 PTS system, N-acetylgalactosamine-specific II component, (99.3% evalue=2.E-74); Escherichia coli ECs4014 N-acetyl-galactosamine / galactosamine PTS system enzyme IIA component (38.9% evalue=3.E-20) YP_071587.1 similar to Yersinia pestis YPO0838 acetylglucosamine-6-phosphate deacetylase (100% evalue=0); Escherichia coli ECs4015 N-acetylgalactosamine-6-phosphate deacetylase (40.4% evalue=1.E-65) YP_071588.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_071589.1 similar to Yersinia pestis YPO0840 conserved hypothetical protein (100% evalue=0); Agrobacterium tumefaciens Atu4561 conserved hypothetical protein (32.4% evalue=7.E-13) YP_071590.1 similar to Yersinia pestis YPO0841 regulatory protein (99.7% evalue=0); Pasteurella multocida PM0600 arylsulfatase regulator (61.5% evalue=1.E-141) YP_071591.1 similar to Yersinia pestis YPO0842 sulfatase (99.8% evalue=0); Escherichia coli ECs2103 sulfatase (40.3% evalue=1.E-110) YP_071592.1 similar to Yersinia pestis YPO0843 hypothetical protein (98.5% evalue=0); Sinorhizobium meliloti SMb20536 hypothetical protein (28.2% evalue=3.E-22) YP_071593.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_071594.1 similar to Yersinia pestis YPO0845 ThiJ/PfpI-family thiamine biogenesis protein (99.4% evalue=1.E-106); Salmonella typhimurium STM1931 araH; intracellular protease/amidase (50.8% evalue=1.E-44) YP_071596.1 similar to Yersinia pestis YPO0846 LacI-family regulatory protein (100% evalue=0); Sinorhizobium meliloti SMb20537 transcriptional regulator protein (27.8% evalue=9.E-24) YP_071597.1 similar to Yersinia pestis YPO0847 sugar transporter (99.7% evalue=0); Ralstonia solanacearum RS04107 exuT2, RSc1080; hexuronate transporter transmembrane protein (46.9% evalue=1.E-116) YP_071598.1 similar to Yersinia pestis YPO0848 glucosidase (99.6% evalue=0); B. halodurans BH0704 glucosidase (52.5% evalue=0) YP_071599.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_071600.1 porin involved in the transport of maltose and maltodextrins YP_071601.1 similar to Yersinia pestis YPO0852 bgaB, pbg; puative beta-galactosidase (100% evalue=0); C. perfringens CPE0167 pbg; beta-galactosidase (51.3% evalue=0) YP_071602.1 similar to Yersinia pestis YPO0853 galactosidase (100% evalue=0); Thermotoga maritima TM1201 arabinogalactan endo-1,4-beta-galactosidase, (49.2% evalue=1.E-104) YP_071603.1 similar to Yersinia pestis YPO0854 maltodextrin permease (100% evalue=1.E-156); B. halodurans BH2021 maltose/maltodextrin transport system permease (69.6% evalue=1.E-110) YP_071604.1 similar to Yersinia pestis YPO0855 maltodextrin transport permease (99.7% evalue=0); Bacillus subtilis BG12437 yvfL; maltose/maltodextrin transport system permease (68.2% evalue=1.E-175) YP_071605.1 similar to Yersinia pestis YPO0856 sugar-binding protein (100% evalue=0); Bacillus subtilis BG12436 yvfK; maltose/maltodextrin transport system substrate-binding protein (49% evalue=1.E-106) YP_071606.1 similar to Yersinia pestis YPO0857 sugar transport ATP-binding protein (99.4% evalue=0); Ralstonia solanacearum RS01463 probable sugar ATP-binding ABC transporter protein (56.3% evalue=1.E-108) YP_071607.1 similar to Yersinia pestis YPO0858 sugar transport ATP-binding protein (99.2% evalue=0); Brucella melitensis BMEI0391 sugar transport ATP-binding protein (52.4% evalue=1.E-133) YP_071608.1 similar to Yersinia pestis YPO0859 sugar transport system permease (99.7% evalue=0); Brucella melitensis BMEI0392 ribose transport system permease RbsC (54.4% evalue=2.E-98) YP_071609.1 similar to Yersinia pestis YPO0860 sugar-binding periplasmic protein (100% evalue=0); Brucella melitensis BMEI0393 D-ribose-binding periplasmic protein precursor (55.3% evalue=2.E-94) YP_071610.1 similar to Yersinia pestis YPO0862 exported protein (100% evalue=8.E-95) YP_071611.1 similar to Yersinia pestis YPO0863 lipoprotein (100% evalue=1.E-162); Escherichia coli b0193 yaeF; hypothetical 32.1 kD lipoprotein in cutF-proS intergenic region precursor (43.2% evalue=1.E-51) YP_071612.1 similar to Yersinia pestis YPO0864 conserved hypothetical protein (99.5% evalue=1.E-128); Caulobacter crescentus CC3691 conserved hypothetical protein (46.3% evalue=1.E-27) YP_071613.1 similar to Yersinia pestis YPO0865 hypothetical protein (99% evalue=2.E-55) YP_071614.1 similar to Yersinia pestis YPO0866 conserved hypothetical protein (99% evalue=7.E-55); Ralstonia solanacearum RS00394 conserved hypothetical protein (46.9% evalue=3.E-12) YP_071615.1 similar to Yersinia pestis YPO0867 membrane protein (100% evalue=1.E-143) YP_071616.1 similar to Yersinia pestis YPO0869 hypothetical protein (100% evalue=1.E-138) YP_071617.1 similar to Yersinia pestis YPO0870 conserved hypothetical protein (99.7% evalue=0); Pseudomonas aeruginosa PA5441 hypothetical protein (32.9% evalue=6.E-86) YP_071618.1 similar to Yersinia pestis YPO0871 colicin immunity protein, 98% identical YP_071619.1 similar to Yersinia pestis YPO872 hypothetical protein, 100% identical. YP_071620.1 similar to Yersinia pestis YPO1484 hypothetical protein (76.9% evalue=9.E-39) YP_071621.1 similar to Yersinia pestis YPO0874 hypothetical protein (100% evalue=0); Pasteurella multocida PM1770 hypothetical, C. elegans (66% evalue=1.E-141) YP_071622.1 similar to Yersinia pestis YPO0875 hypothetical protein (99.1% evalue=1.E-67) YP_071623.1 similar to Yersinia pestis YPO0877 hypothetical protein (72.6% evalue=2.E-37) YP_071624.1 similar to Yersinia pestis YPO0878 regulatory protein (100% evalue=7.E-33); Escherichia coli Z3946 DNA binding protein (59.6% evalue=8.E-16) YP_071626.1 similar to Yersinia pestis YPO0880 primase (99% evalue=0); Salmonella typhi STY4832 Bacteriophage P4 DNA primase (40.8% evalue=1.E-158) YP_071627.1 similar to Yersinia pestis YPO0881 conserved hypothetical protein (100% evalue=2.E-72); Escherichia coli JW2989 ygiT; Hypothetical protein (60.3% evalue=9.E-44) YP_071628.1 similar to Yersinia pestis YPO0882 conserved hypothetical protein (98.9% evalue=2.E-50); Escherichia coli JW2990 ygiU; Hypothetical protein (68% evalue=1.E-31) YP_071629.1 similar to Yersinia pestis YPO4028 regulator (96.6% evalue=1.E-62) YP_071630.1 similar to Yersinia pestis YPO0884 hypothetical protein (100% evalue=2.E-43) YP_071631.1 similar to Salmonella typhi STY4645 phage integrase (39.8% evalue=3.E-62); Salmonella typhimurium STM2739 Fels-2 prophage: similar to int protein in phage 186 (40.1% evalue=7.E-63) YP_071632.1 similar to gpC [Enterobacteria phage P2] gb|AAD03298.1| (AF063097) gpC [Enterobacteria phage P2], E()=7.00e-28, 59% identity. YP_071633.1 similar to (AJ306907) Cox protein [Enterobacteria phage P2], evalue=3e-30 Id=68% YP_071636.1 similar to Salmonella typhi STY3664 conserved hypothetical protein (30.9% evalue=2.E-07) YP_071637.1 similar to Caulobacter crescentus CC0765 conserved hypothetical protein (50% evalue=1.E-07) YP_071638.1 similar to Vibrio cholerae VC2233 DNA polymerase III, epsilon subunit (28.5% evalue=1.E-09); Salmonella typhi STY4637 exonuclease (45.3% evalue=3.E-38) YP_071639.1 similar to Salmonella typhi STY3668 possible endonuclease (43.8% evalue=0); Salmonella typhimurium STM2729 Fels-2 prophage: similar to retron in E coli (43.1% evalue=1.E-179) YP_071640.1 bacteriophage phi CTX; similar to orf34; similar to (AB008550) orf34 [bacteriophage phiCTX], E()=7.00e-05, 34% identity YP_071641.1 similar to Salmonella typhi STY4628 probable capsid portal protein (36.4% evalue=4.E-47); Salmonella typhimurium STM2723 Fels-2 prophage: similar to gpQ, portal vector protein, in phage P2 (36.9% evalue=2.E-47) YP_071642.1 similar to Salmonella typhi STY4627 probable terminase subunit (41.5% evalue=1.E-120); Salmonella typhimurium STM2722 Fels-2 prophage: similar to gpP, ATP charging, in phage P2 (41.3% evalue=1.E-119) YP_071643.1 similar to Salmonella typhi STY3676 capsid scaffolding protein (42.8% evalue=7.E-22); Salmonella typhimurium STM2721 Fels-2 prophage: similar to gpO, capsid scaffold, in phage P2 (27.9% evalue=6.E-23) YP_071644.1 similar to Salmonella typhi STY4625 major capsid protein (30% evalue=2.E-32); Ralstonia solanacearum RS03506 probable bacteriophage protein (29% evalue=4.E-32) YP_071645.1 similar to Salmonella typhi STY4624 phage terminase (23.7% evalue=1.E-09); Salmonella typhimurium STM2719 Fels-2 prophage: similar to gpR in phage 186 (22.8% evalue=1.E-09) YP_071646.1 similar to Salmonella typhi STY4623 capsid completion protein (23.6% evalue=4.E-07); Salmonella typhi STY3679 capsid completion protein (23.2% evalue=2.E-07) YP_071647.1 similar to protein 21 (AY027935) [Haemophilus influenzae phage HP2] YP_071648.1 similar to protein 22 (U24159) [phage HP1] YP_071649.1 similar to protein 23 (AY027935) [Haemophilus influenzae phage HP2] YP_071650.1 similar to orf24 [Haemophilus phage HP1] sp|P51726|YO24_BPHP1 TAIL TUBE PROTEIN (ORF24), E()=1.00e-41, 55% identity. YP_071652.1 probable transmembrane domain: 6 26. YP_071655.1 similar to Escherichia coli ECs2641 tail protein (25.6% evalue=1.E-16); Escherichia coli Z2987 tail fiber component of prophage CP-933T (25.6% evalue=2.E-16) YP_071657.1 similar to (AY027935) orf29 [Haemophilus influenzae phage HP2], E()=1.00e-109, 48% identity. YP_071658.1 similar to (AY027935) orf30 [Haemophilus influenzae phage HP2], E()=8.00e-42, 48% identity. YP_071659.1 similar to (AY027935) orf31 [Phage HP2] evalue=4e-46, Id=36% in the N-terminal region. YP_071660.1 similar to Salmonella typhi STY1073 hypothetical prophage protein (31.7% evalue=1.E-12); Salmonella typhimurium STM2234 tail fiber assembly protein (33.3% evalue=9.E-17) YP_071661.1 similar to (AY027935) orf33 [Haemophilus influenzae phage HP2], E()=1.00e-16, 26% identity. YP_071663.1 similar to Pseudomonas aeruginosa PA0095 conserved hypothetical protein (23.3% evalue=5.E-09) YP_071664.1 similar to Yersinia pestis YPO0887 int; integrase (99.7% evalue=0); Escherichia coli ECs4534 integrase (65.5% evalue=1.E-153) YP_071665.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_071666.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_071667.1 5'-3' single-stranded-DNA-specific exonuclease YP_071668.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_071669.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_071670.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_071671.1 similar to Yersinia pestis YPO0894 creD; membrane protein (99.7% evalue=0); Escherichia coli Z6003 creD; tolerance to colicin E2 (47.4% evalue=1.E-111) YP_071672.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_071673.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_071674.1 similar to Yersinia pestis YPO0896a conserved hypothetical protein (99.2% evalue=2.E-81); Escherichia coli JW2864 ygfX; Hypothetical protein (52.3% evalue=5.E-36) YP_071675.1 similar to Yersinia pestis YPO0897 conserved hypothetical protein (100% evalue=9.E-48); Escherichia coli ECs3769 hypothetical protein (81.8% evalue=2.E-39) YP_071676.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_071677.1 similar to Yersinia pestis YPO0899 membrane protein (100% evalue=3.E-93); Ralstonia solanacearum RS01761 hypothetical transmembrane protein (45.2% evalue=1.E-34) YP_071678.1 similar to Yersinia pestis YPO0900 hemolysin III (99.1% evalue=1.E-129); Salmonella typhimurium STM3049 yqfA; hemolysin (78.4% evalue=3.E-94) YP_071679.1 similar to Yersinia pestis YPO1686 exported protein (61.2% evalue=1.E-111) YP_071680.1 similar to Yersinia pestis YPO1461 hypothetical protein (32.6% evalue=2.E-12) YP_071681.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_071682.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_071683.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_071684.1 similar to Yersinia pestis YPO0908 visC; monooxygenase (100% evalue=0); Salmonella typhimurium STM3056 visC; monooxygenase (73.4% evalue=1.E-170) YP_071685.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_071686.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_071687.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_071688.1 similar to Yersinia pestis YPO0912 conserved hypothetical protein (100% evalue=7.E-56); Escherichia coli Z4247 ygfE; orf, hypothetical protein (79.8% evalue=9.E-45) YP_071689.1 similar to Yersinia pestis YPO0913 5-formyltetrahydrofolate cyclo-ligase-family protein (99.4% evalue=1.E-115); Escherichia coli b2912 ygfA; hypothetical 21.1 kD protein in ssr-serA intergenic region (O182) (69.6% evalue=3.E-72) YP_071690.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_071691.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_071692.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_071693.1 similar to Yersinia pestis YPO0917 yggE; exported protein (99.2% evalue=1.E-139); Salmonella typhi STY3221 conserved hypothetical protein (64.9% evalue=7.E-88) YP_071694.1 Involved in the export of arginine YP_071695.1 similar to Yersinia pestis YPO0919 membrane protein (100% evalue=1.E-157); Salmonella typhi STY3223 membrane protein (66.4% evalue=1.E-105) YP_071696.2 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_071697.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_071698.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_071699.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_071700.1 similar to Yersinia pestis YPO0927 metalloprotease (99.6% evalue=1.E-137); Salmonella typhi STY3237 metalloprotease (73.8% evalue=1.E-104) YP_071701.1 similar to Yersinia pestis YPO0928 Rieske protein (100% evalue=8.E-60); Ralstonia solanacearum RS04099 nagAb, RSc1088; probable ferredoxin subunit of A ring-hydroxylating dioxygenase oxidoreductase (39.3% evalue=6.E-17) YP_071702.1 similar to Yersinia pestis YPO3280 tnp; transposase for the IS1541 insertion element (100% evalue=6.E-89) YP_071703.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_071704.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_071705.1 similar to Yersinia pestis YPO0932 conserved hypothetical protein (98.2% evalue=1.E-96); Escherichia coli b2944 sprT; sprT protein (69.1% evalue=3.E-63) YP_071706.1 similar to Yersinia pestis YPO0933 endA, nucM; endonuclease I (100% evalue=1.E-142); Salmonella typhimurium STM3093 endA; DNA-specific endonuclease I (76.1% evalue=1.E-108) YP_071707.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_071708.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_071709.1 similar to Yersinia pestis YPO0936 conserved hypothetical protein (99.4% evalue=1.E-103); Salmonella typhi STY3249 conserved hypothetical protein (70% evalue=3.E-71) YP_071710.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_071711.1 similar to Yersinia pestis YPO0938 carbon-nitrogen hydrolase (100% evalue=1.E-170); Pseudomonas aeruginosa PA0293 probable hydratase (64.1% evalue=1.E-107) YP_071712.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_071713.1 similar to Yersinia pestis YPO0940 conserved hypothetical protein (99.7% evalue=0); Escherichia coli ECs3827 protein transport (56.9% evalue=1.E-93) YP_071714.1 similar to Yersinia pestis YPO0941 conserved hypothetical protein (99.5% evalue=1.E-127); Salmonella typhi STY3253 conserved hypothetical protein (70.1% evalue=4.E-84) YP_071715.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_071716.1 similar to Yersinia pestis YPO0943 yggT; membrane protein (89.1% evalue=3.E-87); Escherichia coli ECs3828 resistance protein (57.2% evalue=2.E-57) YP_071717.1 similar to Yersinia pestis YPO0944 conserved hypothetical protein (96.8% evalue=2.E-46); Escherichia coli ECs3829 hypothetical protein (81% evalue=5.E-40) YP_071718.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_071719.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_071720.1 similar to Yersinia pestis YPO0947 virulence determinant (94.8% evalue=0); Vibrio cholerae VC1451 RTX toxin RtxA (32.3% evalue=2.E-28) YP_071721.1 similar to Salmonella typhi STY3262 conserved hypothetical protein (59.1% evalue=2.E-76); Escherichia coli ECs3834 hypothetical protein (60% evalue=4.E-76) YP_071722.1 catalyzes the formation of glutamate from glutamine YP_071723.1 similar to Yersinia pestis YPO0950 conserved hypothetical protein (100% evalue=6.E-60); Escherichia coli JW2926 yggL; Hypothetical protein (f118) (78.7% evalue=3.E-46) YP_071724.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_071725.1 similar to Yersinia pestis YPO0952 mutY, mutB; A/G-specific adenine glycosylase (99.4% evalue=0); Escherichia coli b2961 mutY, micA; A/G-specific adenine glycosylase (75.8% evalue=1.E-158) YP_071726.1 similar to Yersinia pestis YPO0953 conserved hypothetical protein (98.8% evalue=8.E-47); Escherichia coli ECs3838 hypothetical protein (83.3% evalue=1.E-39) YP_071727.2 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_071728.2 similar to Yersinia pestis YPO1310 periplasmic substrate-binding transport protein (40.7% evalue=4.E-70) YP_071729.1 similar to Yersinia pestis YPO0956 hydroxamate-type ferrisiderophore receptor (99.7% evalue=0); Pseudomonas aeruginosa PA0151 probable TonB-dependent receptor (50.4% evalue=0) YP_071730.1 similar to Yersinia pestis YPO0957 sugar transport system permease (100% evalue=0); Sinorhizobium meliloti SMb20854 sugar uptake ABC transporter permease (46% evalue=2.E-66) YP_071731.1 similar to Yersinia pestis YPO0958 mglA, rbsA; sugar transport ATP-binding protein (99.5% evalue=0); Sinorhizobium meliloti SMc02337 ATP-binding ABC transporter protein (47.6% evalue=1.E-125) YP_071732.1 similar to Yersinia pestis YPO0959 sugar ABC transporter periplasmic binding protein (99% evalue=1.E-179); Sinorhizobium meliloti SMb20856 sugar uptake ABC transporter periplasmic solute-binding protein precursor (39.3% evalue=1.E-58) YP_071733.1 similar to Yersinia pestis YPO0960 speC; ornithine decarboxylase (99.8% evalue=0); Escherichia coli Z4310 speC; ornithine decarboxylase isozyme (73.3% evalue=0) YP_071734.1 similar to Yersinia pestis YPO0968 insA; insertion sequence protein (98.9% evalue=6.E-49) YP_071735.1 similar to Yersinia pestis YPO1474 exported protein (33.6% evalue=7.E-27) YP_071736.1 similar to Yersinia pestis YPO1473 hypothetical protein (83.5% evalue=0) YP_071737.1 similar to Yersinia pestis YPO0968 insA; insertion sequence protein (96.7% evalue=9.E-48) YP_071739.1 similar to Yersinia pestis YPO1473 hypothetical protein (46.8% evalue=1.E-179) YP_071740.1 similar to Yersinia pestis YPO1472 conserved hypothetical protein (94.3% evalue=0) YP_071741.1 similar to Yersinia pestis YPO1471 ATPase subunit of ATP-dependent protease (96.5% evalue=0) YP_071742.1 similar to Yersinia pestis YPO1470 conserved hypothetical protein (100% evalue=5.E-93) YP_071743.1 similar to Yersinia pestis YPO1469 exported protein (99.6% evalue=0) YP_071744.1 similar to Yersinia pestis YPO1468 membrane protein (98.6% evalue=1.E-131) YP_071745.1 similar to Yersinia pestis YPO1467 conserved hypothetical protein (99.1% evalue=0) YP_071746.1 similar to Yersinia pestis YPO1466 conserved hypothetical protein (100% evalue=0) YP_071747.1 similar to Yersinia pestis YPO1465 conserved hypothetical protein (97.5% evalue=5.E-86) YP_071748.1 similar to Yersinia pestis YPO0981 insA; insertion element protein (93.1% evalue=1.E-43) YP_071749.1 similar to Yersinia pestis YPO0982 lipoprotein (98.4% evalue=5.E-69) YP_071750.1 similar to Yersinia pestis YPO0983 membrane protein (100% evalue=1.E-121); Salmonella typhi STY2608 conserved hypothetical protein (42.1% evalue=1.E-46) YP_071751.1 similar to Yersinia pestis YPO2456 ypeI; N-acylhomoserine lactone synthase YpeI (46.2% evalue=4.E-53) YP_071752.1 similar to Yersinia pestis YPO2457 ypeR; quorum-sensing transcriptional activator YpeR (44.8% evalue=9.E-58) YP_071753.1 similar to Yersinia pestis YPO0986 exported protein (98.6% evalue=0); Thermotoga maritima TM0033 hypothetical protein (26.6% evalue=5.E-34) YP_071754.1 similar to Yersinia pestis YPO0987 exported protein (98.5% evalue=1.E-155) YP_071755.1 similar to Yersinia pestis YPO0988 membrane protein (99.2% evalue=0); Caulobacter crescentus CC0751 multidrug resistance protein, (25% evalue=2.E-19) YP_071756.1 similar to Sinorhizobium meliloti SMa2404 rhbC; RhbC rhizobactin siderophore biosynthesis protein (32.1% evalue=3.E-56); Anabaena all0394 hypothetical protein (28.9% evalue=1.E-53) YP_071757.1 similar to Yersinia pestis YPO0991 iucB; siderophore biosynthesis protein IucB (98.1% evalue=0); S. pombe SPBC17G9.06C spbc17g9.06c; hypothetical protein (42.2% evalue=5.E-41) YP_071758.1 similar to Yersinia pestis YPO0992 iucC; siderophore biosynthesis protein IucC (99.8% evalue=0); Sinorhizobium meliloti SMa2410 rhbF; RhbF rhizobactin siderophore biosynthesis protein RhsF (34.8% evalue=5.E-89) YP_071759.1 deleted EC_number 1.13.12.10; similar to Yersinia pestis YPO0993 iucD; siderophore biosynthesis protein IucD (99.5% evalue=0); Mesorhizobium loti mlr5923 lysine:N6-hydroxylase (35.5% evalue=4.E-65) YP_071760.1 similar to Yersinia pestis YPO0994 iutA; ferric siderophore receptor (99.8% evalue=0); Pseudomonas aeruginosa PA4675 probable TonB-dependent receptor (46.8% evalue=0) YP_071761.1 similar to Yersinia pestis YPO0995 Sodium:galactoside symporter family protein (100% evalue=0); Bacillus subtilis BG12795 gutP, ydjD; probable glucitol symporter (31.7% evalue=1.E-57) YP_071762.1 similar to Mycobacterium tuberculosis Rv3096 hypothetical protein Rv3096 (33.5% evalue=2.E-54); Mycobacterium tuberculosis_CDC1551MT3180 hypothetical protein (33.5% evalue=2.E-54) YP_071763.1 similar to Yersinia pestis YPO0758 LacI-family regulatory protein (99.3% evalue=0); Mesorhizobium loti mll4964 transcriptional regulator, LacI (ribose operon repressor) family (37% evalue=2.E-50) YP_071764.1 similar to Yersinia pestis YPO0759 Sodium:sulfate symporter-family protein (98.6% evalue=0); Pasteurella multocida PM1167 hypothetical HI0608 (60.3% evalue=1.E-154) YP_071765.1 similar to Yersinia pestis YPO0760 membrane protein (100% evalue=3.E-73); Escherichia coli b4011 yjaA; hypothetical 14.4 kD protein in rrfE-metA intergenic region (O127) (40.3% evalue=1.E-16) YP_071766.1 similar to Yersinia pestis YPO0761 hypothetical protein (96.2% evalue=1.E-37) YP_071768.1 similar to Ralstonia solanacearum RS02401 hypothetical protein (33.9% evalue=9.E-13) YP_071773.1 similar to Yersinia pestis YPO0762 conserved hypothetical protein (98.4% evalue=0); Salmonella typhi STY0321 Rhs-family protein (27% evalue=5.E-84) YP_071774.1 similar to Yersinia pestis YPO0763 hypothetical protein (99.7% evalue=0) YP_071775.1 similar to Yersinia pestis YPO3606 Rhs accessory genetic element (77.7% evalue=0) YP_071776.1 similar to Yersinia pestis YPO1672 conserved hypothetical protein (79.4% evalue=0) YP_071777.1 similar to Yersinia pestis YPO1672 conserved hypothetical protein (82.4% evalue=0) YP_071778.1 similar to Yersinia pestis YPO0767 gntP; gluconate transporter (100% evalue=0); Escherichia coli ECs5280 gluconate transport system permease 3 (82.9% evalue=0) YP_071779.1 similar to Yersinia pestis YPO0768 hypothetical protein (100% evalue=5.E-73) YP_071780.1 similar to Yersinia pestis YPO0769 exported protein (99.6% evalue=1.E-163); Salmonella typhimurium STM2516 sinI; outer membrane protein (27% evalue=7.E-13) YP_071781.1 similar to Yersinia pestis YPO0770 ABC-transporter transmembrane protein (99.6% evalue=0); Ralstonia solanacearum RS04233 probable composite ATP-binding transmembrane ABC transporter protein (34% evalue=6.E-85) YP_071782.1 similar to Yersinia pestis YPO0771 ABC-transporter transmembrane protein (99.3% evalue=0); Ralstonia solanacearum RS04232 probable composite ATP-binding transmembrane ABC transporter protein (36.7% evalue=1.E-108) YP_071783.1 similar to Yersinia pestis YPO0772 membrane protein (95.8% evalue=0); Sinorhizobium meliloti SMa2337 transmembrane transport protein (27.2% evalue=1.E-31) YP_071784.1 similar to Yersinia pestis YPO0773 thioesterase (98.4% evalue=1.E-145); Pseudomonas aeruginosa PA4229 pchC; pyochelin biosynthetic protein PchC (38.5% evalue=5.E-41) YP_071785.1 similar to Yersinia pestis YPO0774 conserved hypothetical protein (99.7% evalue=0); Ralstonia solanacearum RS04226 siderophore-like synthase (38.7% evalue=2.E-61) YP_071786.1 similar to Yersinia pestis YPO0775 conserved hypothetical protein (98% evalue=0) YP_071787.1 similar to Yersinia pestis YPO0776 siderophore biosysnthesis protein (96.2% evalue=0); Pseudomonas aeruginosa PA4225 pchF; pyochelin synthetase (34.3% evalue=0) YP_071788.1 similar to Yersinia pestis YPO0778 siderophore biosysnthesis protein (96.9% evalue=0) YP_071789.1 similar to Yersinia pestis YPO1011 TonB-dependent outer membrane receptor (97.9% evalue=0); Anabaena all4026 similar to TonB-dependent receptor (28.4% evalue=8.E-73) YP_071790.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_071791.1 similar to Yersinia pestis YPO1008 integral membrane efflux protein (99.6% evalue=0); Vibrio cholerae VC0863 conserved hypothetical protein (47.5% evalue=1.E-140) YP_071792.1 similar to Yersinia pestis YPO1007 antigenic leucine-rich repeat protein (58.1% evalue=0) YP_071793.1 similar to Yersinia pestis YPO1007 antigenic leucine-rich repeat protein (74% evalue=0) YP_071794.1 similar to Yersinia pestis YPO1004 yapH; autotransporter protein (97.8% evalue=0); Escherichia coli JW1502 aidA; Adhesin AIDA-I precursor (47.2% evalue=1.E-124) YP_071795.1 similar to Yersinia pestis YPO1003 exported protein (98.9% evalue=1.E-107); Salmonella typhimurium STM3650 periplasmic or exported protein (64.4% evalue=5.E-59) YP_071796.1 similar to Yersinia pestis YPO3339 hypothetical protein (27.9% evalue=1.E-33) YP_071797.1 similar to Yersinia pestis YPO1001 integral membrane efflux protein (99.9% evalue=0); Sinorhizobium meliloti SMa1662 drug resistance protein (50.1% evalue=0) YP_071798.1 similar to Yersinia pestis YPO1000 drug efflux protein (97% evalue=0); Sinorhizobium meliloti SMa1664 drug resistance protein (37.3% evalue=1.E-64) YP_071799.1 similar to Yersinia pestis YPO0998 membrane protein (100% evalue=0); Pseudomonas aeruginosa PA2072 conserved hypothetical protein (42.3% evalue=0) YP_071800.1 similar to Yersinia pestis YPO3931 insertion element IS1661 DNA-binding protein (100% evalue=7.E-97) YP_071801.1 similar to Yersinia pestis YPO3932 transposase for insertion sequence IS1661 (99.6% evalue=1.E-150) YP_071802.1 similar to Yersinia pestis YPO1583 transposase for the IS285 insertion element (100% evalue=0) YP_071803.1 similar to Yersinia pestis YPO0754 membrane protein (98.9% evalue=2.E-51); Escherichia coli JW4119 yjeO; Hypothetical protein (27% evalue=3.E-07) YP_071804.1 similar to Yersinia pestis YPO2373 slyB, pcpY; lipoprotein (69.6% evalue=4.E-60); Escherichia coli ECs2350 outer membrane protein (61.9% evalue=5.E-53) YP_071805.1 similar to Yersinia pestis YPO0751 possible membrane protein, 100% identical. YP_071806.1 similar to Yersinia pestis YPO0750 membrane protein (99.3% evalue=1.E-80) YP_071807.1 similar to Yersinia pestis YPO0749 hypothetical protein (100% evalue=1.E-110) YP_071808.1 similar to Yersinia pestis YPO0748 hypothetical protein, 98% identical. YP_071809.1 similar to Yersinia pestis YPO0747 motB, lafU; chemotaxis membrane protein (99% evalue=1.E-168); Escherichia coli ECs0256 motility protein (48.2% evalue=3.E-59) YP_071810.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_071811.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_071812.1 similar to Yersinia pestis YPO0744 flagellar biogenesis protein (91.6% evalue=1.E-75) YP_071813.1 similar to Yersinia pestis YPO0743 flagellar hook-length control protein (86.5% evalue=1.E-180); Vibrio cholerae VC2128 flagellar hook-length control protein FliK, (23.9% evalue=4.E-08) YP_071814.1 similar to Yersinia pestis YPO0742 hypothetical protein (93.5% evalue=7.E-50) YP_071815.1 similar to Yersinia pestis YPO0741 fliS, lafC; flagellar protein (96% evalue=2.E-64); Salmonella typhimurium STM1961 fliS; flagellar biosynthesis; repressor of class 3a and 3b operons (RflA activity) (37.3% evalue=2.E-18) YP_071816.1 similar to Yersinia pestis YPO0740 fliD; flagellar hook-associated protein (85.3% evalue=0); Pseudomonas aeruginosa PA1094 fliD; flagellar capping protein FliD (25.2% evalue=3.E-28) YP_071817.1 similar to Yersinia pestis YPO0739 flaA3; flagellin (79% evalue=1.E-165) YP_071818.1 similar to Yersinia pestis YPO0736 regulatory protein (97.7% evalue=0); Vibrio cholerae VC0984 cholera toxin transcriptional activator (26.5% evalue=6.E-09) YP_071819.1 similar to Yersinia pestis YPO0735 hypothetical protein (98.1% evalue=5.E-56) YP_071820.1 similar to Yersinia pestis YPO0734 hypothetical protein (98.1% evalue=1.E-179) YP_071821.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; in Vibrio parahaemolyticus the protein in this cluster is associated with the lateral flagella YP_071822.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_071823.1 FlgJ; flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; like the lateral flagella FlgJ in Vibrio parahaemolyticus this protein does not contains a C-terminal muramidase domain YP_071824.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_071825.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; the Yersinia have 2 copies of flgH YP_071826.1 makes up the distal portion of the flagellar basal body rod YP_071827.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_071828.1 the hook connects flagellar basal body to the flagellar filament; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_071829.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Vibrio parahaemolyticus protein in this cluster is associated with lateral flagella production YP_071830.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_071831.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Yersinia has 2 copies of flgB and other flagellar genes YP_071832.2 required for the assembly of the flagellar basal body P-ring; the Vibrio parahaemolyticus protein involved with the synthesis of the lateral flagella YP_071833.1 similar to Yersinia pestis YPO0720 flagellar regulatory protein (100% evalue=1.E-43) YP_071834.1 similar to Yersinia pestis YPO0719 hypothetical protein (99% evalue=2.E-56) YP_071835.1 similar to Yersinia pestis YPO0718 hypothetical protein (86.6% evalue=5.E-61) YP_071836.1 involved in type III protein export during flagellum assembly YP_071837.1 binds to and inhibits the function of flagella specific ATPase FliI YP_071838.1 One of three proteins involved in switching the direction of the flagellar rotation YP_071839.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella YP_071840.1 similar to Yersinia pestis YPO0713 fliE; flagellar hook-basal body complex protein (99.2% evalue=1.E-63); Pseudomonas aeruginosa PA1100 fliE; flagellar hook-basal body complex protein FliE (43.6% evalue=2.E-11) YP_071841.1 similar to Yersinia pestis YPO0712 fleR, flbD; sigma-54 transcriptional regulatory protein (99.7% evalue=0); Pseudomonas aeruginosa PA1099 fleR; two-component response regulator (49.5% evalue=8.E-86) YP_071842.1 similar to Yersinia pestis YPO0711 fliM; flagellar motor switch protein (99% evalue=1.E-170) YP_071843.1 similar to Yersinia pestis YPO0710 fliN, mopA; flagellar switch protein (100% evalue=6.E-71); Vibrio cholerae VC2125 flagellar motor switch protein FliN (38.3% evalue=2.E-18) YP_071844.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_071845.1 similar to Yersinia pestis YPO0708 fliQ; flagellar assembly protein (100% evalue=4.E-42); Vibrio cholerae VC2122 flagellar biosynthetic protein FliQ (50% evalue=1.E-17) YP_071846.1 similar to Yersinia pestis YPO0707 fliR, mopE; flagellar assembly protein (100% evalue=1.E-142); Pseudomonas aeruginosa PA1448 fliR; flagellar biosynthetic protein FliR (37.8% evalue=3.E-37) YP_071847.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_071848.1 membrane protein involved in the flagellar export apparatus YP_071849.1 similar to Yersinia pestis YPO0703 lipoprotein (99.4% evalue=1.E-106) YP_071850.1 with FepCDG is involved in the transport of ferric enterobactin YP_071851.1 similar to Yersinia pestis YPO0700 Fimbrial protein (96.4% evalue=0) YP_071852.1 similar to Yersinia pestis YPO0699 fimbrial chaperone protein (100% evalue=1.E-132); Escherichia coli JW2333 yfcS; Hypothetical fimbrial chaperone (43.7% evalue=6.E-57) YP_071853.1 similar to Yersinia pestis YPO0698 outer membrane usher protein (99.7% evalue=0); Salmonella typhimurium STM0196 stfC; fimbrial outer membrane usher (44% evalue=0) YP_071854.1 similar to Yersinia pestis YPO4044 fimbrial protein (34.2% evalue=3.E-19) YP_071855.1 similar to Pseudomonas aeruginosa PA2300 chiC; chitinase (51.7% evalue=1.E-131); Lactococcus lactis L9964 chiA; chitinase (46.2% evalue=1.E-101) YP_071856.1 similar to Listeria monocytogenes lmo2467 similar to chitinase and chitin binding protein (32.8% evalue=3.E-54); Listeria innocua lin2611 similar to chitinase and chitin binding protein (33.4% evalue=5.E-50) YP_071857.1 similar to Salmonella typhi STY0374 possible transmembrane regulator (32% evalue=1.E-10); Salmonella typhimurium STM0341 inner membrane protein (32% evalue=3.E-11) YP_071859.1 similar to Yersinia pestis YPO0695 membrane protein (94.2% evalue=3.E-68); Pasteurella multocida PM0854 hypothetical A. actinmycetemcomitans (34.5% evalue=1.E-22) YP_071860.1 similar to Yersinia pestis YPO0694 membrane protein (92.9% evalue=1.E-152); Pasteurella multocida PM0853 hypothetical A. actinmycetemcomitans (27.1% evalue=2.E-19) YP_071861.1 similar to Pasteurella multocida PM0852 rcpA; rough colony protein A (39.6% evalue=8.E-92); Mesorhizobium loti mlr6335 type II secretion system protein (29.4% evalue=2.E-43) YP_071862.1 not considered as relevant in Y.pestis C0-92 annotation. YP_071863.1 similar to Yersinia pestis YPO0691 hypothetical protein (100% evalue=0); Pasteurella multocida PM0850 unknown (35.2% evalue=2.E-58) YP_071864.1 similar to Yersinia pestis YPO0690 type II secretion protein (99.5% evalue=0); Pasteurella multocida PM0849 tadA; TadA, nonspecific tight adherence protein (63.2% evalue=1.E-152) YP_071865.1 similar to Yersinia pestis YPO0689 membrane protein (100% evalue=1.E-162); Pasteurella multocida PM0848 tadB; TadB, nonspecific tight adherence protein (35.5% evalue=8.E-49) YP_071866.1 similar to Yersinia pestis YPO0688 exported protein (99.6% evalue=1.E-148); Pasteurella multocida PM0847 tadC; TadC, nonspecific tight adherence protein (30.9% evalue=4.E-38) YP_071867.1 similar to Yersinia pestis YPO0687 conserved hypothetical protein (99.1% evalue=1.E-131); Pasteurella multocida PM0846 tadD; TadD, nonspecific tight adherence protein (40.3% evalue=4.E-44) YP_071868.1 similar to Yersinia pestis YPO0686 membrane protein (99.3% evalue=8.E-83) YP_071869.1 similar to Yersinia pestis YPO0685 conserved hypothetical protein (99.4% evalue=5.E-91); Pasteurella multocida PM0844 tadF; TadF, nonspecific tight adherence protein (28.6% evalue=1.E-13) YP_071870.1 similar to Yersinia pestis YPO0684 membrane protein (99.6% evalue=0); Pasteurella multocida PM0843 tadG; TadG, nonspecific tight adherence protein (22.8% evalue=6.E-19) YP_071871.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_071872.1 similar to Yersinia pestis YPO0682 MotA/TolQ/ExbB proton channel family protein (99.5% evalue=1.E-127); Escherichia coli Z4359 exbB; uptake of enterochelin; tonB-dependent uptake of B colicins (71.1% evalue=3.E-88) YP_071873.1 catalyzes the formation of L-homocysteine from cystathionine YP_071874.1 similar to Yersinia pestis YPO0680 DedA-family membrane protein (100% evalue=1.E-122); Escherichia coli ECs3893 hypothetical protein (70.2% evalue=5.E-83) YP_071875.1 similar to Yersinia pestis YPO0679 AraC-family regulatory protein (100% evalue=1.E-168); Salmonella typhimurium STM3163 yqhC; transcriptional regulator (AraC/XylS family) (61.5% evalue=1.E-101) YP_071876.1 similar to Yersinia pestis YPO0678 iron-containing alcohol dehydrogenase (100% evalue=0); Escherichia coli b3011 yqhD; hypothetical oxidoreductase in metC-sufI intergenic region (77.2% evalue=1.E-172) YP_071877.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_071878.1 similar to Escherichia coli ECs3900 hypothetical protein (82.8% evalue=0); Escherichia coli Z4370 hypothetical protein (82.7% evalue=0) YP_071879.1 similar to Yersinia pestis YPO0673 sufI; cell division protein (100% evalue=0); Escherichia coli ECs3901 suppressor of ftsI (74.3% evalue=0) YP_071880.1 similar to Yersinia pestis YPO0672 plsC, parF; acyltransferase (100% evalue=1.E-139); Escherichia coli ECs3902 1-acyl-sn-glycerol-3-phosphate acyltransferase (72.1% evalue=1.E-101) YP_071881.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_071882.1 similar to Yersinia pestis YPO0670 mdaB, mda66; modulator of drug activity (100% evalue=1.E-113); Salmonella typhimurium STM3179 mdaB; NADPH specific quinone oxidoreductase (drug modulator) (69.4% evalue=1.E-78) YP_071883.1 similar to Yersinia pestis YPO0669 crgA; LysR-family regulatory protein (99.6% evalue=1.E-166); Ralstonia solanacearum RS04599 probable transcription regulator protein (66.5% evalue=1.E-101) YP_071884.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_071885.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_071886.1 similar to Yersinia pestis YPO0666 icc; Icc protein homologue (98.9% evalue=1.E-163); Salmonella typhi STY3361 icc; conserved hypothetical protein (71.6% evalue=1.E-116) YP_071887.1 similar to Yersinia pestis YPO0665 conserved hypothetical protein (100% evalue=3.E-78); Escherichia coli JW3001 yqiB; Hypothetical protein (ORF2) (f140) (79.7% evalue=6.E-63) YP_071888.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_071889.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_071890.1 similar to Yersinia pestis YPO0661 exported protein (100% evalue=1.E-127); Salmonella typhimurium STM3187 ygiB; inner membrane protein (75.2% evalue=1.E-92) YP_071891.1 similar to Yersinia pestis YPO0660 conserved hypothetical protein (100% evalue=0); Salmonella typhimurium STM3188 ygiC; glutathionylspermidine synthase (78.4% evalue=0) YP_071892.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_071893.1 DHBP synthase; functions during riboflavin biosynthesis YP_071894.1 similar to Yersinia pestis YPO0656 conserved hypothetical protein (100% evalue=4.E-46); Escherichia coli Z4400 hypothetical protein (89% evalue=2.E-33) YP_071895.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_071896.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_071897.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_071898.1 similar to Yersinia pestis YPO0652 conserved hypothetical protein (100% evalue=0); Salmonella typhi STY3381 conserved hypothetical protein (49.8% evalue=1.E-115) YP_071899.1 similar to Yersinia pestis YPO0651 exported protein (99.5% evalue=1.E-114); Escherichia coli ECs3938 hypothetical protein (71.8% evalue=8.E-83) YP_071900.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_071901.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_071902.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_071903.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_071904.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_071905.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_071906.1 synthesizes RNA primers at the replication forks YP_071907.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_071908.1 similar to Yersinia pestis YPO0642 hypothetical protein (97.4% evalue=4.E-16) YP_071909.1 similar to Yersinia pestis YPO0641 hypothetical protein (100% evalue=3.E-78) YP_071910.1 similar to Yersinia pestis YPO0641 hypothetical protein (49.2% evalue=9.E-30) YP_071911.1 similar to Yersinia pestis YPO1258 conserved hypothetical protein (52.5% evalue=1.E-113) YP_071912.1 similar to Yersinia pestis YPO0631 LysR-family regulatory protein (99% evalue=1.E-178); Pseudomonas aeruginosa PA4174 probable transcriptional regulator (42.6% evalue=2.E-63) YP_071913.1 similar to Yersinia pestis YPO0630 conserved hypothetical protein (99.5% evalue=1.E-139); Pseudomonas aeruginosa PA0859 hypothetical protein (36.5% evalue=5.E-29) YP_071914.1 similar to Yersinia pestis YPO0629 conserved hypothetical protein (100% evalue=2.E-53); Escherichia coli JW1657 hypothetical protein (50% evalue=2.E-24) YP_071915.1 similar to Yersinia pestis YPO0628 translational inhibitor protein (100% evalue=8.E-72); Sinorhizobium meliloti SMc01714 hypothetical transmembrane protein (33% evalue=2.E-12) YP_071916.1 similar to Yersinia pestis YPO0627 translational inhibitor protein (100% evalue=8.E-66); P. horikoshii PH0854 hypothetical protein (52.4% evalue=9.E-31) YP_071917.1 similar to Yersinia pestis YPO0626 conserved hypothetical protein (99.4% evalue=2.E-96); Salmonella typhi STY4219 DNA-binding protein (33.9% evalue=2.E-28) YP_071918.1 similar to Yersinia pestis YPO0625 hypothetical protein (100% evalue=2.E-81); Mesorhizobium loti mlr1698 unknown protein (31.9% evalue=1.E-14) YP_071919.1 similar to Yersinia pestis YPO0624 membrane protein (99.7% evalue=0); Halobacterium VNG0436G nhaC1; Na+/H+ antiporter (26.5% evalue=2.E-41) YP_071920.1 similar to Yersinia pestis YPO0623 aminotransferase (100% evalue=0); P. abyssi PAB0525 aspC; aspartate aminotransferase (33% evalue=9.E-55) YP_071921.1 similar to Yersinia pestis YPO0622 hypothetical protein, 100% identical. YP_071922.1 similar to Yersinia pestis YPO0621 hypothetical protein, 100% identical. YP_071923.1 similar to Yersinia pestis YPO0620 exported protein (100% evalue=7.E-58) YP_071924.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_071925.1 similar to Yersinia pestis YPO0618 membrane protein (99.4% evalue=0); Escherichia coli JW4042 yjcQ; Hypothetical protein (27.9% evalue=5.E-45) YP_071926.1 similar to Yersinia pestis YPO0617 membrane protein (100% evalue=0); Ralstonia solanacearum RS03674 outer membrane chanel lipoprotein (24.1% evalue=2.E-27) YP_071927.1 similar to Yersinia pestis YPO0616 glycosyl hydrolase (99.7% evalue=0); Pseudomonas aeruginosa PA1726 bglX; periplasmic beta-glucosidase (39.3% evalue=1.E-140) YP_071928.1 similar to Yersinia pestis YPO0615 exported protein (98.1% evalue=2.E-86) YP_071929.1 similar to Yersinia pestis YPO0614 permease (99.6% evalue=1.E-151); Agrobacterium tumefaciens AGR_L_3392 transport system inner membrane protein (37.2% evalue=1.E-49) YP_071930.1 similar to Yersinia pestis YPO0613 permease (99.3% evalue=1.E-167); B. halodurans BH0902 araP; L-arabinose transport system permease (34.8% evalue=9.E-42) YP_071931.1 similar to Yersinia pestis YPO0612 sugar binding protein (99.7% evalue=0); Mesorhizobium loti mll0854 probable secreted solute-binding protein (24.4% evalue=4.E-13) YP_071932.1 similar to Yersinia pestis YPO0611 LacI-family regulatory protein (99% evalue=0); Listeria innocua lin1838 similar to transcription regulators (LacI family) (38.3% evalue=4.E-53) YP_071933.1 similar to Yersinia pestis YPO0610 hypothetical protein (99.7% evalue=0); Listeria innocua lin1839 some similarities to cellobiose-phosphorylase (37.2% evalue=0) YP_071934.1 similar to Yersinia pestis YPO1720 sugar ABC transporter (53.9% evalue=1.E-111) YP_071935.1 similar to Yersinia pestis YPO0608 membrane protein (99.7% evalue=0) YP_071936.1 similar to Yersinia pestis YPO0607 exported protein (99.6% evalue=0) YP_071937.1 similar to Yersinia pestis YPO0606 yapF; autotransporter protein (99% evalue=0); Ralstonia solanacearum RS04855 probable hemagglutinin-related protein (22.6% evalue=7.E-10) YP_071939.1 similar to hypothetical protein [Neisseria meningitidis Z2491] pir||B81783, E() =4.00e-03, 40% identity. CDS not found in Y.pestis CO-92. YP_071941.1 similar to Neisseria meningitidis NMB1489 hypothetical protein (50.2% evalue=4.E-41); Neisseria meningitidis NMB0488 hypothetical protein (52% evalue=1.E-42) YP_071943.1 similar to Yersinia pestis YPO2490 hemolysin (63% evalue=0) YP_071944.1 similar to Yersinia pestis YPO2491 hemolysin activator protein (81.6% evalue=0) YP_071945.1 similar to Yersinia pestis YPO0597 terY; tellurium resistance protein (100% evalue=1.E-116) YP_071946.1 similar to Yersinia pestis YPO0596 terX; tellurium resistance protein (100% evalue=1.E-121) YP_071947.1 similar to Yersinia pestis YPO0597 terY; tellurium resistance protein (47.2% evalue=3.E-52) YP_071948.1 similar to Yersinia pestis YPO0597 terY; tellurium resistance protein (40% evalue=4.E-37) YP_071949.1 similar to Yersinia pestis YPO0593 hypothetical protein (96.5% evalue=0) YP_071950.1 similar to Yersinia pestis YPO0592 kinase (99.7% evalue=0) YP_071951.1 similar to Yersinia pestis YPO0590 hdeD; membrane protein (100% evalue=3.E-99); Escherichia coli b3511 hdeD; hdeD protein (46.2% evalue=1.E-45) YP_071952.1 similar to Yersinia pestis YPO0589 fadH, fadH1; 2,4-dienoyl-CoA reductase (99.7% evalue=0); Escherichia coli b3081 fadH; 2,4-dienoyl-CoA reductase (NADPH) (2,4-dienoyl coenzyme A reductase) (72.7% evalue=0) YP_071953.1 similar to Yersinia pestis YPO0588 ribosomal RNA small subunit methyltransferase D (100% evalue=0); Escherichia coli ECs3966 ribosomal RNA small subunit methyltransferase D (63.3% evalue=1.E-139) YP_071954.1 similar to Yersinia pestis YPO1004 yapH; autotransporter protein (43.3% evalue=1.E-79) YP_071955.1 similar to Yersinia pestis YPO0586 conserved hypothetical protein (100% evalue=4.E-96); Salmonella typhimurium STM3221 ygjP; metal-dependent hydrolase (80.5% evalue=4.E-72) YP_071956.1 similar to Yersinia pestis YPO0585 MocA-family oxidoreductase (100% evalue=0); Escherichia coli ECs3969 hypothetical protein (74.1% evalue=1.E-135) YP_071957.1 involved in the import of serine and threonine coupled with the import of sodium YP_071958.1 similar to Yersinia pestis YPO0582 membrane protein (100% evalue=7.E-97); Escherichia coli Z4443 ygjV; orf, hypothetical protein (66% evalue=1.E-66) YP_071959.1 similar to Yersinia pestis YPO0581 uxaA; altronate hydrolase (99.1% evalue=0); Escherichia coli Z4444 uxaA; altronate hydrolase (79% evalue=0) YP_071960.1 catalyzes the formation of D-tagaturonate from D-altronate YP_071961.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_071962.1 similar to Yersinia pestis YPO0577 exuT; ExuT transport protein (100% evalue=0); Escherichia coli JW3064 exuT; Hexuronate transporter (84.1% evalue=0) YP_071963.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_071964.1 similar to Yersinia pestis YPO0575 lipoprotein (98.9% evalue=1.E-102) YP_071965.1 similar to Yersinia pestis YPO0574 yqjA; DedA-family membrane protein (100% evalue=1.E-132); Escherichia coli JW3066 yqjA; Hypothetical protein (78.6% evalue=1.E-100) YP_071966.1 similar to Yersinia pestis YPO0573 membrane protein (99.2% evalue=2.E-68); Salmonella typhimurium STM3227 yqjB; outer membrane protein (43.3% evalue=4.E-15) YP_071967.1 similar to Yersinia pestis YPO0572 exported protein (100% evalue=6.E-66); Salmonella typhimurium STM3228 yqjC; periplasmic protein (44% evalue=1.E-23) YP_071968.1 similar to Yersinia pestis YPO0570 yqjD; membrane protein (100% evalue=1.E-50); Escherichia coli JW3069 yqjD; Hypothetical protein (69.3% evalue=5.E-33) YP_071969.1 similar to Yersinia pestis YPO0569a conserved hypothetical protein (100% evalue=3.E-66); Salmonella typhimurium STM3230 yqjE; inner membrane protein (64.6% evalue=6.E-40) YP_071970.1 similar to Yersinia pestis YPO0569 conserved hypothetical protein (97.8% evalue=4.E-47); Salmonella typhi STY3411 conserved hypothetical protein (39.3% evalue=4.E-17) YP_071971.1 similar to Yersinia pestis YPO0568 membrane protein (99.1% evalue=7.E-65); Escherichia coli b3101 yqjF; hypothetical 17.2 kD protein in exuR-tdcC intergenic region (75.5% evalue=4.E-53) YP_071972.1 similar to Escherichia coli b3102 yqjG; hypothetical 37.4 kD protein in exuR-tdcC intergenic region (O328) (77% evalue=1.E-151); Escherichia coli JW3073 yqjG; Hypothetical protein (o328) (77% evalue=1.E-151) YP_071973.1 similar to Yersinia pestis YPO3545 lysR-family transcriptional regulatory protein (99.6% evalue=1.E-164); Escherichia coli b3105 yhaJ; hypothetical transcriptional regulator in exuR-tdcC intergenic region (89.1% evalue=1.E-146) YP_071974.1 similar to Yersinia pestis YPO3546 conserved hypothetical protein (99.1% evalue=1.E-133); Salmonella typhi STY3416 conserved hypothetical protein (71.7% evalue=7.E-92) YP_071975.1 similar to Yersinia pestis YPO3547 tetrapyrrole methylase (100% evalue=1.E-167); Escherichia coli b3146 yraL; hypothetical 31.3 kD protein in agaI-mtr intergenic region (F286) (85.3% evalue=1.E-135) YP_071976.1 similar to Yersinia pestis YPO3548 exported protein (99.8% evalue=0); Salmonella typhimurium STM3264 yraM; paral transglycosylase (55.9% evalue=0) YP_071977.1 similar to Yersinia pestis YPO3549 conserved hypothetical protein (100% evalue=2.E-63); Salmonella typhimurium STM3265 yraN; endonuclease (57.3% evalue=4.E-31) YP_071978.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_071979.1 similar to Yersinia pestis YPO3551 exported protein (99.4% evalue=2.E-99); Salmonella typhimurium STM3267 yraP; paral periplasmic protein (73.8% evalue=6.E-73) YP_071980.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_071981.1 similar to Yersinia pestis YPO3553 elbB, elb2; enhancing lycopene biosynthesis protein 2 (100% evalue=1.E-119); Salmonella typhi STY3506 conserved hypothetical protein (65.8% evalue=6.E-79) YP_071982.1 similar to Yersinia pestis YPO3554 hypothetical protein, 97% identical YP_071983.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_071984.1 similar to Yersinia pestis YPO3556 conserved hypothetical protein (100% evalue=1.E-180); Escherichia coli ECs4090 hypothetical protein (78.7% evalue=1.E-140) YP_071985.2 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_071986.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_071987.1 similar to Yersinia pestis YPO3559 exported protein (98.7% evalue=2.E-83) YP_071988.1 similar to Yersinia pestis YPO3560 sspB; stringent starvation protein B (100% evalue=9.E-96); Escherichia coli ECs4101 stringent starvation protein B (72.5% evalue=1.E-67) YP_071989.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_071990.1 forms a direct contact with the tRNA during translation YP_071991.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_071992.1 similar to Yersinia pestis YPO3564 conserved hypothetical protein (100% evalue=0); Salmonella typhi STY3526 ATP/GTP-binding protein (66.4% evalue=1.E-139) YP_071993.1 similar to Yersinia pestis YPO3565 membrane protein (100% evalue=3.E-73); Salmonella typhimurium STM3347 yhcB; periplasmic protein (80.3% evalue=2.E-53) YP_071994.1 similar to Yersinia pestis YPO3566 degQ, hhoA; protease (100% evalue=0); Salmonella typhi STY3528 degQ; serine protease (72.9% evalue=0) YP_071995.1 similar to Yersinia pestis YPO3568 degS, hhoB, htrH; protease (100% evalue=0); Escherichia coli b3235 degS, hhoB, htrH; protease degS precursor (71.2% evalue=1.E-136) YP_071996.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_071997.1 similar to Yersinia pestis YPO3570 BolA-like protein (98.8% evalue=4.E-44); Escherichia coli ECs4069 hypothetical protein (82.1% evalue=1.E-34) YP_071998.1 similar to Yersinia pestis YPO3571 anti-sigma B factor antagonist (100% evalue=2.E-49); Escherichia coli ECs4070 hypothetical protein (43.3% evalue=4.E-17) YP_071999.1 similar to Yersinia pestis YPO3572 yrbC; exported protein (100% evalue=1.E-116); Salmonella typhimurium STM3310 yrbC; ABC superfamily (atp&memb), transport protein (77.5% evalue=9.E-92) YP_072000.1 similar to Yersinia pestis YPO3573 yrbD; membrane protein (99.4% evalue=1.E-101); Salmonella typhi STY3490 possible exported protein (67.5% evalue=3.E-68) YP_072001.1 similar to Yersinia pestis YPO3574 yrbE; membrane protein (100% evalue=1.E-142); Escherichia coli Z4557 yrbE; ABC transporter permease (82.6% evalue=1.E-122) YP_072002.1 ATP-binding subunit of a ABC toluene efflux transporter YP_072003.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_072004.1 similar to Yersinia pestis YPO3577 conserved hypothetical protein (100% evalue=0); Salmonella typhimurium STM3315 yrbH; polysialic acid capsule expression protein (78.6% evalue=1.E-147) YP_072005.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_072006.1 similar to Yersinia pestis YPO3579 yrbK; exported protein (99.4% evalue=1.E-102); Escherichia coli JW3166 yrbK; Hypothetical protein (o191) (56.4% evalue=3.E-58) YP_072007.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_072008.1 similar to Yersinia pestis YPO3581 yhbG; probable ABC transporter ATP-binding protein (100% evalue=1.E-131); Escherichia coli JW3168 yhbG; probable ABC transporter ATP-binding protein (88.7% evalue=1.E-117) YP_072009.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_072010.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_072011.1 similar to Yersinia pestis YPO3585 ptsN, rpoP; nitrogen regulatory IIA protein (100% evalue=2.E-84); Escherichia coli Z4567 ptsN; phosphotransferase system enzyme IIA, regulates N metabolism (86.1% evalue=3.E-69) YP_072012.1 similar to Yersinia pestis YPO3586 conserved hypothetical protein (100% evalue=1.E-161); Escherichia coli Z4568 yhbJ; orf, hypothetical protein (94.3% evalue=1.E-153) YP_072013.1 similar to Yersinia pestis YPO3587 ptsO, npr, rpoR; phosphocarrier protein (100% evalue=4.E-43); Salmonella typhi STY3503 ptsO; phosphocarrier protein (nitrogen related hpr) (85.5% evalue=1.E-37) YP_072014.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_072015.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_072016.1 similar to Yersinia pestis YPO3590 conserved hypothetical protein (93.7% evalue=1.E-61); Salmonella typhi STY4798 yjgF; conserved hypothetical protein (89% evalue=3.E-59) YP_072017.1 similar to Yersinia pestis YPO3699 exported protein (100% evalue=4.E-87) YP_072018.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_072019.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_072020.1 similar to Yersinia pestis YPO3696 treC, olgH; trehalose-6-phosphate hydrolase (100% evalue=0); Salmonella typhi STY4793 treC; trehalose-6-phosphate hydrolase (73.1% evalue=0) YP_072021.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_072022.1 similar to Yersinia pestis YPO3694 cytochrome (100% evalue=6.E-66); Salmonella typhi STY4778 cybC; soluble cytochrome b562 (52.3% evalue=1.E-31) YP_072023.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_072024.1 similar to Yersinia pestis YPO3691 conserved hypothetical protein (97.8% evalue=1.E-97); Escherichia coli ECs5211 alpha helix protein (78.5% evalue=6.E-76) YP_072025.1 similar to Yersinia pestis YPO3690 ribonuclease inhibitor (100% evalue=3.E-48); Escherichia coli Z4598 yhcO; orf, hypothetical protein (53% evalue=2.E-18) YP_072026.1 similar to Yersinia pestis YPO3689 ribonuclease (100% evalue=1.E-85); Clostridium acetobutylicum CAC0843 ribonuclease precursor (barnase), secreted. (41.5% evalue=2.E-25) YP_072027.1 similar to Salmonella typhi STY2911 gabD; succinate-semialdehyde dehydrogenase (56.8% evalue=1.E-155); Salmonella typhimurium STM2791 gabD; succinate-semialdehyde dehydrogenase I, NADP-dependent (57% evalue=1.E-156) YP_072028.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_072029.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_072030.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_072031.1 similar to Yersinia pestis YPO3683 probable lysR-family transcriptional regulatory protein (99.3% evalue=1.E-171); Escherichia coli ECs4116 transcriptional regulator LYSR-type (80.7% evalue=1.E-137) YP_072032.1 similar to Yersinia pestis YPO3682 lysR-family transcriptional regulatory protein (99.3% evalue=1.E-163) YP_072033.1 similar to Yersinia pestis YPO3681 insecticial toxin (96.2% evalue=0) YP_072035.1 similar to Yersinia pestis YPO3678 tcaC; insecticidal toxin complex (91.9% evalue=0); Salmonella typhimurium PSLT039 spvB; Salmonella plasmid virulence: hydrophilic protein (45% evalue=4.E-78) YP_072036.1 similar to Yersinia pestis YPO3677 phage-related protein (100% evalue=6.E-55); Escherichia coli ECs1621 holin protein (45.6% evalue=3.E-19) YP_072037.1 similar to Yersinia pestis YPO3676 phage-related protein (98.4% evalue=1.E-76); Agrobacterium tumefaciens Atu0462 endolysin (58.1% evalue=1.E-36) YP_072038.1 similar to Yersinia pestis YPO3675 exported protein (98.3% evalue=1.E-58) YP_072039.1 similar to Yersinia pestis YPO3674 insecticidal toxin (76.9% evalue=0) YP_072040.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_072041.1 similar to Yersinia pestis YPO3671 carbon-nitrogen hydrolase (100% evalue=1.E-167); Vibrio cholerae VC0421 conserved hypothetical protein (48.4% evalue=6.E-71) YP_072042.1 similar to Yersinia pestis YPO3670 exported protein (99.2% evalue=0); Salmonella typhimurium STM3369 yhdP; paral protease (50.6% evalue=0) YP_072043.1 involved in the processing of the 5'end of 16S rRNA YP_072044.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_072045.1 part of cell wall structural complex MreBCD; transmembrane component YP_072046.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_072047.1 functions in MreBCD complex in some organisms YP_072048.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_072049.1 similar to Yersinia pestis YPO3663 yhdH; probable zinc-binding dehydrogenase (100% evalue=0); Escherichia coli ECs4125 dehydrogenase (74.6% evalue=1.E-140) YP_072050.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_072051.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_072052.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_072053.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_072054.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_072055.1 similar to Yersinia pestis YPO3657a yhdT; membrane protein (100% evalue=1.E-41); Escherichia coli Z4617 yhdT; orf, hypothetical protein (69.6% evalue=8.E-28) YP_072056.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_072057.2 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_072058.1 similar to Yersinia pestis YPO3655 conserved hypothetical protein (100% evalue=0); Escherichia coli ECs4132 dehydrogenase (87.8% evalue=1.E-164) YP_072059.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_072060.1 similar to Yersinia pestis YPO3652 hypothetical protein (100% evalue=7.E-89) YP_072061.1 similar to Yersinia pestis YPO3651 GntR-family transcriptional regulatory protein (98.2% evalue=1.E-115); Mesorhizobium loti mll6786 transcriptional regulator (37.1% evalue=2.E-33) YP_072062.1 similar to Yersinia pestis YPO3650 metabolite transport protein (99.5% evalue=0); Thermoplasma volcanium TVG1213986 shikimate transporter (26.5% evalue=9.E-43) YP_072063.1 similar to Yersinia pestis YPO3649 gamma carboxymuconolactone decarboxylase (98.4% evalue=2.E-71); S. C3502 solfataricus SSO2884 pcaC; 4-carboxymucolactone decarboxylase (49.1% evalue=1.E-28) YP_072064.1 similar to Yersinia pestis YPO3648 2-hydroxy-3-oxopropionate reductase (99.6% evalue=1.E-164); Ralstonia solanacearum RS05573 mmsB, RSp0649; probable 3-hydroxyisobutyrate dehydrogenase oxidoreductase (34.2% evalue=6.E-38) YP_072065.1 similar to Yersinia pestis YPO3647 conserved hypothetical protein (99.2% evalue=1.E-162); A. fulgidus AF1509 A. fulgidus predicted coding region AF1509 (27.3% evalue=3.E-14) YP_072066.1 similar to Yersinia pestis YPO3646 pcp, pcpY, slyB; outer membrane lipoprotein (100% evalue=7.E-81) YP_072067.1 similar to Yersinia pestis YPO3644 cspa1; major cold shock protein Cspa1 (98.5% evalue=2.E-34) YP_072068.1 similar to Yersinia pestis YPO3644 cspa1; major cold shock protein Cspa1 (98.5% evalue=2.E-34) YP_072069.1 similar to Yersinia pestis YPO3644 cspa1; major cold shock protein Cspa1 (97.1% evalue=5.E-34) YP_072070.1 similar to Yersinia pestis YPO3641 hypothetical protein (99.4% evalue=0); Salmonella typhimurium STM0567 ATPase involved in DNA repair (58.5% evalue=1.E-125) YP_072071.1 similar to Yersinia pestis YPO3640 exported protein (99.7% evalue=0); Sinorhizobium meliloti SMc00620 hypothetical signal peptide protein (53% evalue=1.E-129) YP_072072.1 YghU; B2989; one of eight glutathione transferases from E. coli YP_072073.1 similar to Yersinia pestis YPO3638 phosphosugar isomerase/binding protein (99.5% evalue=1.E-108); Listeria innocua lin0502 similar to sugar-phosphate isomerase (44.5% evalue=5.E-42) YP_072074.1 similar to Yersinia pestis YPO3637 carbohydrate kinase (100% evalue=0); A. thalianan At4g30310 F17I23.350; protein (50.4% evalue=1.E-162) YP_072075.1 similar to Yersinia pestis YPO3636 ABC transporter, permease (99.3% evalue=1.E-170); Escherichia coli Z0419 permease component of transport system, probably ribose specific (58.7% evalue=6.E-91) YP_072076.1 similar to Yersinia pestis YPO3635 branched-chain amino acid transport system, permease component (99.6% evalue=0); Escherichia coli Z0418 permease component of transport system, probably ribose specific (57.5% evalue=1.E-105) YP_072077.1 similar to Yersinia pestis YPO3634 ABC transporter ATP binding protein (100% evalue=0) YP_072078.1 similar to Yersinia pestis YPO3633 periplasmic binding protein (100% evalue=0); Escherichia coli ECs0374 sugar-binding protein (53.3% evalue=1.E-95) YP_072079.2 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_072080.1 similar to Yersinia pestis YPO3631 exported protein (99.4% evalue=0) YP_072081.1 similar to Yersinia pestis YPO3630 yjcE; Na(+)/H(+) exchanger protein (100% evalue=0); Escherichia coli ECs5047 hypothetical protein (75.3% evalue=0) YP_072082.1 similar to Yersinia pestis YPO3629 yjcD; xanthine/uracil permease (99.7% evalue=0); Escherichia coli ECs3757 oxidoreductase (87.5% evalue=0) YP_072083.1 similar to Yersinia pestis YPO3628 DNA-damage-inducible protein (100% evalue=5.E-31) YP_072084.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_072085.1 similar to Yersinia pestis YPO3626 ssuC; aliphatic sulfonates transport permease (100% evalue=1.E-148); Pseudomonas aeruginosa PA3443 alkanesulfonate transport system permease (80.9% evalue=1.E-119) YP_072086.1 catalyzes the release of sulfite from alkanesulfonates YP_072087.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease YP_072088.1 similar to Yersinia pestis YPO3623 ssuE; NAD(P)H-dependent FMN reductase (100% evalue=1.E-102); Escherichia coli ECs1020 NAD(P)H-dependent FMN reductase (61.7% evalue=5.E-54) YP_072089.1 similar to Yersinia pestis YPO3622 deoxyribose-phosphate aldolase (99.5% evalue=1.E-131); Methanothermobacter thermautotrophicus MTH818 deoxyribose-phosphate aldolase (34.1% evalue=3.E-26) YP_072090.1 similar to Yersinia pestis YPO3621 probable carbohydrate kinase (99.3% evalue=1.E-172); Pseudomonas aeruginosa PA1950 rbsK; ribokinase (39.2% evalue=4.E-48) YP_072091.1 similar to Yersinia pestis YPO3620 carbohydrate transport protein (98.8% evalue=2.E-92); H. influenzae HI0501 rbsD; D-ribose transport system permease (34% evalue=9.E-16) YP_072092.1 similar to Yersinia pestis YPO3619 araC-family transcriptional regulatory protein (99.6% evalue=1.E-173); Pseudomonas aeruginosa PA3571 mmsR; transcriptional regulator MmsR (23.5% evalue=6.E-20) YP_072093.1 similar to Yersinia pestis YPO3618 oxidoreductase (100% evalue=0); Mesorhizobium loti mll1735 hypothetical protein (43.9% evalue=5.E-84) YP_072094.1 similar to Yersinia pestis YPO3617 hypothetical protein (100% evalue=1.E-172); Mesorhizobium loti mll1734 unknown protein (51.4% evalue=5.E-92) YP_072095.1 similar to Yersinia pestis YPO3613 Rhs accessory genetic element (96.8% evalue=7.E-32) YP_072097.1 similar to Yersinia pestis YPO3615 membrane protein (98.1% evalue=0); Ralstonia solanacearum RS05482 rhs-related transmembrane protein (33% evalue=0) YP_072098.1 similar to Yersinia pestis YPO3614 conserved hypothetical protein (100% evalue=7.E-78); Ralstonia solanacearum RS05481 conserved hypothetical protein (36.4% evalue=5.E-22) YP_072099.1 similar to Yersinia pestis YPO3613 Rhs accessory genetic element (98.9% evalue=0) YP_072100.1 similar to Yersinia pestis YPO3612 transcriptional regulatory protein (100% evalue=2.E-70); Vibrio cholerae VC1464 transcriptional repressor RstR (33.6% evalue=3.E-12) YP_072101.1 similar to Yersinia pestis YPO3611 hypothetical protein (80.3% evalue=8.E-17) YP_072103.1 similar to Yersinia pestis YPO3608 exported protein (99.6% evalue=0) YP_072104.1 similar to Yersinia pestis YPO3607 conserved hypothetical protein (100% evalue=1.E-87); Salmonella typhi STY0320 hypothetical protein (35.7% evalue=1.E-17) YP_072105.1 similar to Yersinia pestis YPO3613 Rhs accessory genetic element (83.8% evalue=0) YP_072106.1 similar to Yersinia pestis YPO3605 conserved hypothetical protein (100% evalue=6.E-95) YP_072107.1 similar to Yersinia pestis YPO3603 exported protein (99.7% evalue=0); Escherichia coli Z0250 macrophage toxin (57.3% evalue=0) YP_072108.1 similar to Yersinia pestis YPO3602 conserved hypothetical protein (100% evalue=0); Escherichia coli ECs0220 hypothetical protein (53.3% evalue=4.E-71) YP_072109.1 similar to Yersinia pestis YPO3601 conserved hypothetical protein (99.1% evalue=1.E-127); Escherichia coli ECs0222 hypothetical protein (50.2% evalue=1.E-47) YP_072110.1 similar to Yersinia pestis YPO3600 hypothetical protein (100% evalue=1.E-151) YP_072111.1 similar to Yersinia pestis YPO3599 clpB2; Clp ATPase (100% evalue=0); Escherichia coli ECs0223 ATP-dependent Clp proteinase ATP-binding chain (67.2% evalue=0) YP_072112.1 similar to Yersinia pestis YPO3598 membrane protein (100% evalue=1.E-148); Escherichia coli ECs0224 membrane protein (62.5% evalue=4.E-85) YP_072113.1 similar to Yersinia pestis YPO3597 conserved hypothetical protein (100% evalue=0); Escherichia coli ECs0225 hypothetical protein (53.8% evalue=1.E-131) YP_072114.1 similar to Yersinia pestis YPO3596 lipoprotein (100% evalue=1.E-101); Escherichia coli ECs0226 hypothetical lipoprotein (46.9% evalue=4.E-47) YP_072115.1 similar to Yersinia pestis YPO3595 conserved hypothetical protein (99.7% evalue=0); Escherichia coli ECs0227 hypothetical protein (45.2% evalue=6.E-98) YP_072116.1 similar to Yersinia pestis YPO3594 conserved hypothetical protein (99.7% evalue=0); Escherichia coli ECs0228 hypothetical protein (57.8% evalue=1.E-104) YP_072117.1 similar to Escherichia coli ECs0229 hypothetical protein (50.9% evalue=0); Escherichia coli Z0260 hypothetical protein (50.9% evalue=0) YP_072118.1 similar to Yersinia pestis YPO3705 conserved hypothetical protein (100% evalue=4.E-79); Escherichia coli ECs0230 hypothetical protein (35.8% evalue=4.E-20) YP_072119.1 similar to Yersinia pestis YPO3706 conserved hypothetical protein (99.7% evalue=0); Vibrio cholerae VCA0108 conserved hypothetical protein (77.1% evalue=0) YP_072120.1 similar to Yersinia pestis YPO3707 conserved hypothetical protein (99.3% evalue=4.E-87); Escherichia coli Z0264 hypothetical protein (62.6% evalue=8.E-52) YP_072121.1 similar to Yersinia pestis YPO3708 conserved hypothetical protein (99.4% evalue=1.E-97); Escherichia coli Z0266 hypothetical protein (80.2% evalue=7.E-80) YP_072122.1 similar to Yersinia pestis YPO3709 hypothetical protein (95.6% evalue=1.E-46) YP_072123.1 similar to Yersinia pestis YPO3710 malM, molA; maltose operon periplasmic protein (99.6% evalue=1.E-167); Salmonella typhi STY4428 malM; maltose operon periplasmic protein (50.6% evalue=3.E-82) YP_072124.1 porin involved in the transport of maltose and maltodextrins YP_072125.1 with malEFG is involved in import of maltose/maltodextrin YP_072126.1 similar to Yersinia pestis YPO3713 hypothetical protein, 100% identical. YP_072127.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_072128.1 with MalKGE is involved in maltose transport into the cell YP_072129.1 with MalKFE is involved in the transport of maltose into the cell YP_072130.1 similar to Yersinia pestis YPO3717 yjbA; membrane protein (100% evalue=2.E-70); Escherichia coli b4030 yjbA; hypothetical 15.6 kD protein in pgi-xylE intergenic region (67.6% evalue=1.E-45) YP_072131.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_072132.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_072133.1 similar to Yersinia pestis YPO3721 hemolysin (99.6% evalue=0) YP_072134.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_072135.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_072136.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_072137.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates YP_072138.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_072139.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_072140.1 similar to Salmonella typhi STY4398 yrdA; transferase (73.5% evalue=3.E-72); Salmonella typhimurium STM3399 yrdA; ferripyochelin binding protein (73.5% evalue=2.E-72) YP_072141.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_072142.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_072143.1 similar to Yersinia pestis YPO0245 DNA-binding protein (99.4% evalue=1.E-108); Salmonella typhimurium STM3403 yrdD; DNA topoisomerase (71.3% evalue=9.E-77) YP_072144.1 similar to Yersinia pestis YPO0244 conserved hypothetical protein (100% evalue=2.E-80); Salmonella typhi STY4393 smg; conserved hypothetical protein (71.3% evalue=4.E-61) YP_072145.1 similar to Yersinia pestis YPO0243 conserved hypothetical protein (99.7% evalue=0); Escherichia coli ECs4151 hypothetical protein (54.2% evalue=1.E-107) YP_072146.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_072147.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_072148.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_072149.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_072150.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_072151.1 similar to Yersinia pestis YPO0237 conserved hypothetical protein (100% evalue=1.E-32); Escherichia coli JW3253 yhdL; Hypothetical protein (73.6% evalue=5.E-20) YP_072152.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_072153.1 is a component of the macrolide binding site in the peptidyl transferase center YP_072154.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_072155.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_072156.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_072157.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_072158.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_072159.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_072160.1 late assembly protein YP_072161.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_072162.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_072163.1 binds 5S rRNA along with protein L5 and L25 YP_072164.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_072165.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_072166.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_072167.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_072168.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_072169.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_072170.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_072171.1 one of the stabilizing components for the large ribosomal subunit YP_072172.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_072173.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_072174.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_072175.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_072176.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_072177.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_072178.2 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_072179.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_072180.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_072181.1 iron storage protein YP_072182.1 similar to Yersinia pestis YPO0205 bfd; bacterioferritin-associated ferredoxin (100% evalue=2.E-31); Salmonella typhimurium STM3444 bfd; Bacterioferritin-associated ferredoxin (56.2% evalue=8.E-18) YP_072183.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_072184.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_072185.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_072186.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_072187.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_072188.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_072189.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_072190.1 similar to Yersinia pestis YPO0196 DNA-binding protein (100% evalue=1.E-132); Escherichia coli ECs4197 hypothetical protein (86.6% evalue=1.E-115) YP_072191.1 rotamase YP_072192.1 similar to Yersinia pestis YPO0194 conserved hypothetical protein (100% evalue=5.E-34); Salmonella typhimurium STM3454 slyX; cytoplasmic protein (69.4% evalue=2.E-22) YP_072193.1 rotamase YP_072194.1 similar to Yersinia pestis YPO0192 conserved hypothetical protein (100% evalue=8.E-39); Salmonella typhi STY4342 yheV; conserved hypothetical protein (65% evalue=2.E-20) YP_072195.1 involved in potassium efflux YP_072196.1 required for KefB activity YP_072197.1 similar to Salmonella typhi STY4339 yheS; probable ABC transporter ATP-binding protein (81.3% evalue=0); Salmonella typhimurium STM3459 yheS; ATPase component of ABC transporter with duplicated ATPase domain (81.5% evalue=0) YP_072198.1 similar to Yersinia pestis YPO0187 glycosyl transferase (99.3% evalue=0); Escherichia coli ECs4493 regulator (29.1% evalue=2.E-30) YP_072199.1 similar to Yersinia pestis YPO0186 sugar transferase (98.7% evalue=0); Escherichia coli ECs4507 lipopolysaccharide core biosynthesis protein RfaQ (22.3% evalue=1.E-10) YP_072200.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_072201.1 similar to Yersinia pestis YPO0184 tauC, ssiC; taurine transport system permease (100% evalue=1.E-157); Escherichia coli ECs0421 taurine transport system permease (77.6% evalue=1.E-112) YP_072202.1 Part of the ABC transporter complex tauABC involved in taurine import YP_072203.1 with TauB and TauC is responsible for taurine uptake. YP_072204.1 similar to Yersinia pestis YPO0181 ABC-transport protein (99.5% evalue=1.E-111); Mesorhizobium loti mll1430 hypothetical protein (40.4% evalue=1.E-34) YP_072205.1 similar to Yersinia pestis YPO0180 conserved hypothetical protein (100% evalue=0); Escherichia coli b3353 yheT; hypothetical 38.5 kD protein in kifb-prkB intergenic region (69.5% evalue=1.E-134) YP_072206.1 similar to Yersinia pestis YPO0179 conserved hypothetical protein (98.7% evalue=2.E-38); Salmonella typhi STY4334 yheU; conserved hypothetical protein (78.5% evalue=7.E-27) YP_072207.1 similar to Yersinia pestis YPO0178 prk; phosphoribulokinase 1 (100% evalue=1.E-167); Escherichia coli b3355 prkB; probable phosphoribulokinase (phosphopentokinase) (PRK) (86.4% evalue=1.E-146) YP_072208.1 similar to Yersinia pestis YPO2790 membrane protein (42.1% evalue=6.E-22) YP_072209.1 similar to Yersinia pestis YPO0176 conserved hypothetical protein (100% evalue=1.E-71); Escherichia coli b3356 yhfA; hypothetical 14.5 kD protein in prkB-CRP intergenic region (F134) (86.2% evalue=1.E-59) YP_072210.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_072211.1 similar to Yersinia pestis YPO0174 membrane protein (98.5% evalue=0); Salmonella typhimurium STM3467 yhfK; inner membrane protein (57% evalue=0) YP_072212.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_072213.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_072214.1 similar to Yersinia pestis YPO0168 conserved hypothetical protein (99.4% evalue=0); Escherichia coli Z5875 yjgR; orf, hypothetical protein (67.4% evalue=0) YP_072215.1 similar to Yersinia pestis YPO0167 ppiA, rotA; peptidyl-prolyl cis-trans isomerase A (100% evalue=1.E-104); Escherichia coli Z4724 ppiA; peptidyl-prolyl cis-trans isomerase A (rotamase A) (79.4% evalue=2.E-83) YP_072216.1 similar to Yersinia pestis YPO0166 6-phospho-beta-glucosidase, (99.7% evalue=0); Vibrio cholerae VC1284 6-phospho-beta-glucosidase (55.8% evalue=1.E-139) YP_072217.1 similar to Yersinia pestis YPO0165 LacI-family transcriptional regulator (100% evalue=0); Vibrio cholerae VC1286 transcriptional regulator, LacI family (47.2% evalue=2.E-76) YP_072218.1 similar to Yersinia pestis YPO0164 membrane receptor protein (98.3% evalue=0); Pseudomonas aeruginosa PA3790 oprC; outer membrane protein OprC (58.8% evalue=0) YP_072219.1 similar to Yersinia pestis YPO0163 conserved integral membrane protein (99.7% evalue=0); Escherichia coli Z4725 yhfC; transport (74.8% evalue=1.E-170) YP_072220.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_072221.1 similar to Yersinia pestis YPO0161 nirB; nitrite reductase (99.7% evalue=0); Salmonella typhimurium STM3474 nirB; nitrite reductase, large subunit (84.1% evalue=0) YP_072222.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_072223.1 member of the FNT family of formate and nitrite transporters YP_072224.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin YP_072225.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_072226.2 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_072227.1 similar to Yersinia pestis YPO0155 rpe; ribulose-phosphate 3-epimerase (100% evalue=1.E-125); Escherichia coli b3386 rpe, dod; ribulose-phosphate 3-epimerase (pentose-5-phosphate 3-epimerase) (PPE) (R5P3E) (87% evalue=1.E-109) YP_072228.1 similar to Yersinia pestis YPO0154 dam; DNA adenine methylase (100% evalue=1.E-159); Salmonella typhi STY4312 dam; DNA adenine methylase (70% evalue=1.E-109) YP_072229.1 similar to Yersinia pestis YPO0153 conserved hypothetical membrane protein (99.3% evalue=0); Escherichia coli ECs4230 membrane protein DamX (40.8% evalue=5.E-60) YP_072230.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_072231.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_072232.2 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_072233.1 similar to Yersinia pestis YPO0149 membrane protein (99.1% evalue=2.E-66) YP_072234.1 similar to Yersinia pestis YPO0148 membrane protein (98.9% evalue=1.E-108) YP_072235.1 similar to Yersinia pestis YPO0147 membrane protein (99% evalue=1.E-113); Escherichia coli Z4748 yrfC; orf, hypothetical protein (28.3% evalue=1.E-10) YP_072236.1 similar to Yersinia pestis YPO0146 hypothetical protein (98.3% evalue=1.E-168); Salmonella typhi STY4304 yrfD; conserved hypothetical protein (25.3% evalue=1.E-17) YP_072237.3 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_072238.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_072239.1 similar to Yersinia pestis YPO0142 membrane protein (99.7% evalue=0); Escherichia coli JW3361 yrfF; Hypothetical protein (53.4% evalue=0) YP_072240.1 similar to Yersinia pestis YPO0141 conserved hypothetical protein (100% evalue=1.E-133); Escherichia coli JW3362 yrfG; Hypothetical protein (68.3% evalue=3.E-87) YP_072241.1 similar to Yersinia pestis YPO0140 hslR; heat shock protein 15 (100% evalue=2.E-73); Escherichia coli JW3363 hslR; Hsp15. DNA/RNA binding heat shock protein (73.3% evalue=5.E-52) YP_072242.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_072243.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_072244.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_072245.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_072246.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_072247.1 similar to Yersinia pestis YPO0134 conserved hypothetical protein (99.8% evalue=0); Escherichia coli JW3370 yhgF; Hypothetical protein (82.8% evalue=0) YP_072248.1 similar to Yersinia pestis YPO0133 feoA; hypothetical ferrous iron transport protein A (100% evalue=4.E-36); Escherichia coli b3408 feoA; ferrous iron transport protein A (77.4% evalue=4.E-24) YP_072249.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_072250.1 similar to Yersinia pestis YPO0131 conserved hypothetical protein (100% evalue=8.E-44); Escherichia coli b3410 yhgG; hypothetical 8.7 kD protein in feoB-bioH intergenic region (O78) (58.2% evalue=4.E-17) YP_072251.1 similar to Yersinia pestis YPO0130 exported protein (100% evalue=5.E-43); Salmonella typhi STY0095 probable secreted protein (46.5% evalue=1.E-13) YP_072252.1 similar to Yersinia pestis YPO0129 bioH; biotin biosynthesis protein (99.2% evalue=1.E-149); Salmonella typhi STY4287 bioH; biotin biosynthesis protein (67.2% evalue=4.E-99) YP_072253.1 involved in high-affinity gluconate transport YP_072254.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_072255.1 amylomaltase; acts to release glucose from maltodextrins YP_072256.1 similar to Salmonella typhi STY4282 malP; maltodextrin phosphorylase (75.5% evalue=0); Salmonella typhimurium STM3514 malP; maltodextrin phosphorylase (76% evalue=0) YP_072257.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_072258.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_072259.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_072260.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_072261.1 similar to Yersinia pestis YPO3934 hypothetical protein (97.2% evalue=2.E-80) YP_072262.1 similar to Yersinia pestis YPO3935 membrane protein (99.3% evalue=2.E-88) YP_072263.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_072264.1 similar to Yersinia pestis YPO3938 glgP, glgY; glycogen phosphorylase (99.8% evalue=0); Salmonella typhimurium STM3534 glgP; glycogen phosphorylase (80.8% evalue=0) YP_072265.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_072266.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_072267.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_072268.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_072269.1 similar to Yersinia pestis YPO3943 membrane protein (99.1% evalue=0); Escherichia coli JW2114 yehU, yehV; Hypothetical protein (67.3% evalue=0) YP_072270.1 similar to Yersinia pestis YPO3944 invasin (76.3% evalue=0) YP_072271.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_072272.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_072273.1 similar to Yersinia pestis YPO3951 hypothetical protein (96.8% evalue=3.E-69); Pseudomonas aeruginosa PA0092 hypothetical protein (36.2% evalue=1.E-09) YP_072274.1 similar to Yersinia pestis YPO3951 hypothetical protein (75.3% evalue=3.E-53); Pseudomonas aeruginosa PA0092 hypothetical protein (35.2% evalue=8.E-10) YP_072275.1 similar to Yersinia pestis YPO3951 hypothetical protein (76.7% evalue=8.E-56); Pseudomonas aeruginosa PA0092 hypothetical protein (34.3% evalue=2.E-09) YP_072276.1 similar to Yersinia pestis YPO1258 conserved hypothetical protein (60.7% evalue=1.E-73) YP_072277.1 similar to Yersinia pestis YPO3953 gluconokinase (100% evalue=4.E-93) YP_072278.1 similar to Yersinia pestis YPO3954 gntT, usgA, gntM; gluconate permease (99.7% evalue=0); Escherichia coli ECs4257 high-affinity transport of gluconate / gluconate permease (85.1% evalue=0) YP_072279.1 similar to Yersinia pestis YPO3955 gntR; gluconate utilization system Gnt-I transcriptional repressor (99.6% evalue=0); Salmonella typhimurium STM3543 gntR; transcriptional repressor gnt-I, gntUKR (GalR/LacI familiy) (80% evalue=1.E-151) YP_072280.1 similar to Yersinia pestis YPO3956 conserved hypothetical protein (100% evalue=1.E-136); Salmonella typhimurium STM3544 yhhW; cytoplasmic protein (77.9% evalue=1.E-105) YP_072281.1 similar to Yersinia pestis YPO3957 hypothetical protein, 99% identical YP_072282.1 similar to Yersinia pestis YPO3958 response regulator protein (97.5% evalue=1.E-128); Escherichia coli ECs5067 regulatory protein (72% evalue=3.E-93) YP_072283.1 similar to Yersinia pestis YPO3959 PfkB family carbohydrate kinase (99.7% evalue=0); Escherichia coli Z5686 kinase (79.5% evalue=1.E-147) YP_072284.1 similar to Yersinia pestis YPO3960 class-II fructose-bisphosphate aldolase (100% evalue=1.E-159); Escherichia coli ECs5069 fructose-bisphosphate aldolase (84.9% evalue=1.E-135) YP_072285.1 similar to Yersinia pestis YPO3961 hypothetical protein (99.5% evalue=1.E-136); Escherichia coli Z5688 hypothetical protein (73% evalue=1.E-101) YP_072286.1 similar to Yersinia pestis YPO3962 sugar-binding transport protein (100% evalue=1.E-173); Escherichia coli Z5689 periplasmic ribose-binding protein of ABC transport system (87.5% evalue=1.E-154) YP_072287.1 similar to Yersinia pestis YPO3963 sugar transport system permease (100% evalue=0); Escherichia coli Z5690 permease of ribose ABC transport system (89.2% evalue=1.E-157) YP_072288.1 similar to Yersinia pestis YPO3964 sugar transport ATP-binding protein (99.8% evalue=0); Escherichia coli ECs5073 ATP-binding component of sugar ABC transporter (85.3% evalue=0) YP_072289.1 similar to Yersinia pestis YPO3965 hybrid two-component system regulatory protein (99.6% evalue=0); Escherichia coli ECs5074 histidine protein kinase (71.9% evalue=1.E-141) YP_072290.1 similar to Yersinia pestis YPO3966 conserved hypothetical protein (99.4% evalue=0); Escherichia coli ECs4364 hypothetical protein (78.8% evalue=0) YP_072291.1 similar to Yersinia pestis YPO3967 phosphate transport protein (99.5% evalue=0); Escherichia coli ECs4365 low-affinity phosphate transport (75.5% evalue=0) YP_072292.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_072293.1 similar to Yersinia pestis YPO3970 uspA; universal stress protein A (100% evalue=3.E-80); Escherichia coli ECs4367 universal stress protein UspA (93.7% evalue=6.E-73) YP_072294.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_072295.1 similar to Yersinia pestis YPO3973 metalloprotease (97.9% evalue=0); Pseudomonas aeruginosa PA1249 aprA; alkaline metalloproteinase precursor (47.3% evalue=1.E-80) YP_072296.1 predicted SAM-dependent methyltransferase YP_072297.1 similar to Yersinia pestis YPO3975 opdA, prlC; oligopeptidase A (99.5% evalue=0); Escherichia coli b3498 prlC, opdA; oligopeptidase A (80.5% evalue=0) YP_072298.1 similar to Yersinia pestis YPO3976 conserved hypothetical protein (98.9% evalue=1.E-163); Salmonella typhi STY4206 conserved hypothetical protein (80.3% evalue=1.E-136) YP_072299.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_072300.1 similar to Yersinia pestis YPO3978 regulatory protein (97.8% evalue=0); H. influenzae HI0093 hypothetical protein HI0093 (39.2% evalue=2.E-59) YP_072301.1 similar to Yersinia pestis YPO3979 GntP family permease (99.2% evalue=0); Salmonella typhi STY2731 permease (76.3% evalue=0) YP_072302.1 similar to Yersinia pestis YPO3980 glxK; glycerate kinase (99.2% evalue=0); Salmonella typhi STY2730 glycerate kinase (67.6% evalue=1.E-141) YP_072303.1 similar to Yersinia pestis YPO3982 hypothetical protein (64.4% evalue=3.E-63) YP_072304.1 similar to Yersinia pestis YPO3983 conserved hypothetical protein (83.6% evalue=1.E-142); Xylella fastidiosa XF0155 hypothetical protein (42.5% evalue=2.E-59) YP_072305.1 similar to Yersinia pestis YPO3984 yapE; autotransporter protein (97.3% evalue=0); Agrobacterium tumefaciens AGR_pAT_511 BapA protein (24.3% evalue=2.E-46) YP_072306.1 similar to Yersinia pestis YPO3985 membrane protein (98.6% evalue=0); Escherichia coli Z4935 yhjD; orf, hypothetical protein (69.8% evalue=1.E-121) YP_072307.1 similar to Yersinia pestis YPO3986 cdh; CDP-diacylglycerol pyrophosphatase (97.6% evalue=1.E-146); Escherichia coli JW3889 cdh; CDP diacylglycerol pyrophosphatase (version 1) (51.6% evalue=3.E-69) YP_072308.1 similar to Yersinia pestis YPO3987 exported protein (96.1% evalue=0); Pseudomonas aeruginosa PA4879 conserved hypothetical protein (50.7% evalue=0) YP_072309.1 in Escherichia coli this protein is involved in flagellar function YP_072310.1 similar to Yersinia pestis YPO3989 tautomerase (100% evalue=4.E-31); Neisseria meningitidis_A NMA1685 tautomerase (68.1% evalue=5.E-19) YP_072311.1 similar to Yersinia pestis YPO3990 kdgK; 2-dehydro-3-deoxygluconokinase (99.6% evalue=1.E-179); Salmonella typhimurium STM3612 kdgK; ketodeoxygluconokinase (74.5% evalue=1.E-131) YP_072312.1 similar to Yersinia pestis YPO3991 insulinase family protease (100% evalue=0); Escherichia coli JW3495 yhjJ; Hypothetical protein (62.1% evalue=1.E-178) YP_072313.1 involved in the transport of C4-dicarboxylates across the membrane YP_072314.1 similar to Yersinia pestis YPO3993 exported protein (99.3% evalue=2.E-85) YP_072315.1 similar to Yersinia pestis YPO3994 pelY; periplasmic pectate lyase precursor (100% evalue=0) YP_072316.1 similar to Yersinia pestis YPO3995 exported protein (100% evalue=1.E-134) YP_072317.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein YP_072318.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_072319.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_072320.2 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_072321.1 similar to Yersinia pestis YPO4001 dppC; dipeptide transport system permease (100% evalue=1.E-168); Salmonella typhimurium STM3628 dppC; ABC superfamily (membrane), dipeptide transport protein 2 (87.3% evalue=1.E-150) YP_072322.1 transports peptides consisting of two or three amino acids YP_072323.1 similar to Yersinia pestis YPO4003 dppA; periplasmic dipeptide transport protein (99.8% evalue=0); Salmonella typhi STY4168 dppA; periplasmic dipeptide transport protein precursor (85.9% evalue=0) YP_072324.1 similar to Yersinia pestis YPO4005 hemolysin activator protein (98.9% evalue=0) YP_072325.1 similar to Yersinia pestis YPO4006 exported protein (99.5% evalue=0) YP_072326.1 membrane protein regulates uhpT expression YP_072327.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_072328.1 similar to Yersinia pestis YPO4012 uhpA; two-component system response regulator (100% evalue=1.E-105); Escherichia coli Z5159 uhpA; response regulator, positive activator of uhpT transcription (sensor, uhpB) (66.4% evalue=6.E-67) YP_072329.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_072330.1 similar to Yersinia pestis YPO4014 membrane protein (100% evalue=0) YP_072331.1 similar to Yersinia pestis YPO4015 amino acid permease (99.3% evalue=0); Pseudomonas aeruginosa PA5097 glycine betaine/proline transport system permease (73.2% evalue=0) YP_072332.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_072333.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_072334.1 similar to Yersinia pestis YPO4020 membrane protein (100% evalue=1.E-170) YP_072335.1 Catalyzes the formation of malnoyl-CoA, which in turn controls the rate of fatty acid metabolism YP_072336.1 similar to Yersinia pestis YPO4022 iron transport protein (100% evalue=1.E-177); Brucella melitensis BMEII0607 ferric anguibactin-binding protein (48% evalue=6.E-72) YP_072337.1 similar to Yersinia pestis YPO4023 iron transport permease (99.6% evalue=1.E-174); Agrobacterium tumefaciens Atu2474 ABC transporter, membrane spanning protein (53.8% evalue=1.E-100) YP_072338.1 similar to Yersinia pestis YPO4024 iron transport permease (99.7% evalue=1.E-180); Brucella melitensis BMEII0605 ferric anguibactin transport system permease FatC (52.1% evalue=2.E-83) YP_072339.1 similar to Yersinia pestis YPO4025 iron ABC transporter, ATP-binding protein (98.8% evalue=1.E-138); Brucella melitensis BMEII0604 iron(III) dicitrate transport ATP-binding protein FecE (63.3% evalue=2.E-89) YP_072340.1 similar to Salmonella typhi STY4036 DNA-binding protein (43.5% evalue=4.E-12); Salmonella typhimurium STM3755 rhuM; cytoplasmic protein (68.5% evalue=1.E-32) YP_072342.1 similar to Yersinia pestis YPO4033 phage integrase (97.1% evalue=2.E-32); Escherichia coli ECs0289 integrase (68.1% evalue=1.E-22) YP_072343.1 similar to Escherichia coli Z1664 unknown (61.1% evalue=3.E-97); Escherichia coli Z1226 unknown (61.1% evalue=3.E-97) YP_072344.1 similar to Escherichia coli b2646 ypjF; hypothetical 12.3 kD protein in alpA-gabD intergenic region (67.3% evalue=2.E-34); Escherichia coli JW2627 ypjF; Hypothetical protein (67.3% evalue=2.E-34) YP_072345.1 similar to Escherichia coli b0266 yagB; hypothetical 13.2 kD protein in perR-argF intergenic region (74.7% evalue=5.E-38); Escherichia coli JW0259 yagB; Hypothetical protein (74.7% evalue=5.E-38) YP_072346.1 similar to Escherichia coli b2644 yfjY; hypothetical 18.0 kD protein in alpA-gabD intergenic region (61.6% evalue=9.E-50); Escherichia coli JW2625 yfjY, yfjZ; Hypothetical protein (o160) (61.6% evalue=9.E-50) YP_072349.1 similar to Escherichia coli ECs1395 hypothetical protein (40.8% evalue=1.E-34); Escherichia coli Z1650 unknown (40.8% evalue=1.E-34) YP_072350.1 similar to Yersinia pestis YPO3592 insertion sequence IS100, ATP-binding protein (55.2% evalue=6.E-22) YP_072351.1 similar to Escherichia coli b0277 yagK; hypothetical 24.5 kD protein in argF-intf intergenic region (33.1% evalue=1.E-23); Escherichia coli JW0271 yagK; Hypothetical protein (o208) (33.1% evalue=1.E-23) YP_072352.1 similar to Yersinia pestis YPO3591 transposase for insertion sequence IS100 (100% evalue=0) YP_072353.1 similar to Yersinia pestis YPO3592 insertion sequence IS100, ATP-binding protein (100% evalue=1.E-142) YP_072354.1 similar to Clostridium acetobutylicum CAC0328 predicted metal-dependent hydrolase (30.4% evalue=2.E-24); Brucella melitensis BMEII0448 zinc metallopeptidases (34.3% evalue=3.E-32) YP_072355.1 similar to Methanocaldococcus jannaschii MJECL40 type I restriction enzyme, R subunit (28.3% evalue=4.E-76); Brucella melitensis BMEII0449 type I restriction-modification system restriction subunit (30.8% evalue=2.E-88) YP_072356.1 similar to Salmonella typhi STY4036 DNA-binding protein (78.7% evalue=1.E-146); Salmonella typhimurium STM3755 rhuM; cytoplasmic protein (77.9% evalue=1.E-154) YP_072357.1 similar to Salmonella typhimurium STM4524 hsdS; specificity determinant for hsdM and hsdR (35.9% evalue=3.E-26); C. jejuni Cj1051c restriction modification enzyme (35.2% evalue=3.E-33) YP_072358.1 similar to Staphylococcus aureus_N315 SA0391 hsdM; probable type I site-specific deoxyribonuclease [Pathogenicity island SaPIn2] (38.2% evalue=4.E-95); Brucella melitensis BMEII0451 type I restriction-modification system methylation subunit (39.3% evalue=5.E-98) YP_072360.1 similar to Salmonella typhi STY2056 transposase (100% evalue=1.E-177); A. thalianan At1g47875 T2E6.26; transposase (100% evalue=1.E-177) YP_072362.1 similar to Escherichia coli ECs4534 integrase (82.2% evalue=0); Escherichia coli Z5087 intL; integrase for prophage 933L and the LEE pathogenicity island (82.2% evalue=0) YP_072363.1 similar to Yersinia pestis YPO4034 AraC-family transcriptional regulatory protein (100% evalue=0); Escherichia coli ECs4452 regulator of xyl operon (79.4% evalue=0) YP_072364.1 similar to Yersinia pestis YPO4035 sugar transport system permease (100% evalue=0); Escherichia coli ECs4451 membrane component of xylose transport system (84.5% evalue=0) YP_072365.1 with XylFH is part of the high affinity xylose ABC transporter YP_072366.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity YP_072367.1 catalyzes the interconversion of D-xylose to D-xylulose YP_072368.1 similar to Yersinia pestis YPO4039 xylB; xylulose kinase (99.7% evalue=0); Escherichia coli ECs4447 xylulokinase (71.9% evalue=0) YP_072369.1 similar to Yersinia pestis YPO4040 exported protein (99.3% evalue=0); Escherichia coli JW0706 ybgO; Hypothetical protein (31.8% evalue=1.E-38) YP_072370.1 similar to Yersinia pestis YPO4041 fimbrial chaperone (99.6% evalue=1.E-145); Escherichia coli Z0869 ybgP; chaperone (47.4% evalue=7.E-61) YP_072371.1 similar to Salmonella typhi STY3176 stdB; probable outer membrane fimbrial usher protein (46.9% evalue=0); Salmonella typhimurium STM3028 stdB; outer membrane usher protein (46.8% evalue=0) YP_072372.1 similar to Yersinia pestis YPO4044 fimbrial protein (100% evalue=3.E-98); Salmonella typhimurium STM3029 stdA; fimbrial-like protein (37% evalue=5.E-22) YP_072373.1 similar to Yersinia pestis YPO4045 membrane protein (99.6% evalue=0); Salmonella typhimurium STM3658 yiaH; inner membrane protein (58.9% evalue=1.E-109) YP_072374.1 similar to Yersinia pestis YPO0996 insertion element IS1661 DNA-binding protein (100% evalue=1.E-101) YP_072375.1 similar to Yersinia pestis YPO3932 transposase for insertion sequence IS1661 (99.2% evalue=1.E-149) YP_072376.1 catalyzes the formation of L-proline from L-ornithine YP_072377.1 similar to Yersinia pestis YPO4089 pyridoxal-phosphate dependent enzyme (99.6% evalue=1.E-179); Thermotoga maritima TM0356 threonine dehydratase catabolic (44.1% evalue=4.E-61) YP_072378.1 similar to Salmonella typhi STY3967 yidR; ATP/GTP-binding protein (62.1% evalue=1.E-151); Salmonella typhimurium STM3811 yidR; cytoplasmic protein (62.1% evalue=1.E-151) YP_072379.1 similar to Yersinia pestis YPO4086 lipoprotein (97.2% evalue=9.E-58); Escherichia coli b3688 yidQ; hypothetical 14.8 kD protein in ibpA-gyrB intergenic region (43.2% evalue=1.E-19) YP_072380.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_072381.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_072382.1 similar to Yersinia pestis YPO4083 yidE; membrane protein (99.8% evalue=0); Salmonella typhimurium STM3807 yidE; paral transport protein (75.8% evalue=0) YP_072383.2 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_072384.1 similar to Yersinia pestis YPO4081 membrane protein (99.3% evalue=2.E-76) YP_072385.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_072386.1 Involved in the metabolism of aromatic amino acids YP_072387.1 similar to Yersinia pestis YPO4077 conserved hypothetical protein (99.5% evalue=1.E-118); Vibrio cholerae VC2666 conserved hypothetical protein (39.6% evalue=4.E-33) YP_072388.1 similar to Yersinia pestis YPO4076 yiaD; lipoprotein (100% evalue=1.E-118); Salmonella typhimurium STM3645 yiaD; outer membrane lipoprotein (79.4% evalue=7.E-93) YP_072389.1 similar to Yersinia pestis YPO4075 acetyltransferase (97.3% evalue=4.E-84); Salmonella typhi STY4159 yiaC; acetyltransferase (46.9% evalue=4.E-35) YP_072390.1 similar to Yersinia pestis YPO4074 tag; DNA-3-methyladenine glycosylase (100% evalue=1.E-112); Escherichia coli JW3518 tag; DNA-3-methyladenine glycosidase I (3-methyladenine-dna glycosylase I (69.7% evalue=5.E-75) YP_072391.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_072392.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_072393.1 similar to Yersinia pestis YPO4070 yiaF; exported protein (99.1% evalue=1.E-130); Salmonella typhimurium STM3647 yiaF; outer membrane lipoprotein (52.1% evalue=2.E-62) YP_072394.1 similar to Yersinia pestis YPO4068 mtlA; PTS system, mannitol-specific IIABC component (99.8% evalue=0); Salmonella typhi STY4111 mtlA; mannitol-specific enzyme II of phosphotransferase system (82.4% evalue=0) YP_072395.1 similar to Yersinia pestis YPO4067 mtlD; mannitol-1-phosphate 5-dehydrogenase (98.9% evalue=0); Escherichia coli ECs4476 mannitol-1-phosphate dehydrogenase (76.1% evalue=1.E-160) YP_072396.1 Acts as a repressor of the mtlAD operon YP_072397.1 similar to Yersinia pestis YPO4065 conserved hypothetical protein (100% evalue=2.E-60); Salmonella typhimurium STM3689 yibL; cytoplasmic protein (62.9% evalue=6.E-33) YP_072398.1 similar to Yersinia pestis YPO4064 hypothetical protein (100% evalue=2.E-83) YP_072399.1 similar to Yersinia pestis YPO4063 membrane protein (99% evalue=4.E-58); Salmonella typhi STY0296 hypothetical protein (32.9% evalue=1.E-11) YP_072400.1 similar to Yersinia pestis YPO4062 tar, cheM; methyl-accepting chemotaxis protein II (99.6% evalue=0); Salmonella typhimurium STM1919 cheM; methyl accepting chemotaxis protein II, aspartate sensor-receptor (45.9% evalue=1.E-101) YP_072401.1 Mn; SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_072402.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_072403.1 similar to Salmonella typhi STY3839 fdoG; formate dehydrogenase-O, major subunit (84.9% evalue=0); Salmonella typhimurium STM4037 fdoG; formate dehydrogenase (84.5% evalue=0) opal codon at position 4688685-7 for selenocysteine, same as in Escherichia coli; selenocysteine tRNA i YP_072404.1 similar to Yersinia pestis YPO4057 fdoH; formate dehydrogenase-O, iron-sulfur subunit (100% evalue=0); Salmonella typhimurium STM4036 fdoH; formate dehydrogenase-O, Fe-S subunit (86.3% evalue=1.E-154) YP_072405.1 cytochrome b556(FDO) component; heme containing YP_072406.1 required for the formation of active formate dehydrogenase YP_072407.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_072408.1 similar to Pasteurella multocida PM1766 selB; selenocysteine-specific elongation factor (45.5% evalue=1.E-152); Escherichia coli Z5011 selB; selenocysteinyl-tRNA-specific translation factor (58.5% evalue=0) YP_072409.1 similar to Yersinia pestis YPO4050 membrane protein (97.2% evalue=2.E-57) YP_072410.1 similar to Yersinia pestis YPO4049 membrane protein (99.4% evalue=1.E-105) YP_072411.1 similar to Yersinia pestis YPO4048 mdfA, cmr; multidrug translocase (100% evalue=0); Escherichia coli JW0826 mdfA; Multidrag translocase (chloramphenicol resistance pump CMR) (73% evalue=1.E-167) YP_072412.1 similar to Yersinia pestis YPO3932 transposase for insertion sequence IS1661 (99.6% evalue=1.E-150) YP_072413.1 similar to Yersinia pestis YPO0996 insertion element IS1661 DNA-binding protein (100% evalue=1.E-101) YP_072414.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_072415.1 negatively supercoils closed circular double-stranded DNA YP_072416.2 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_072417.1 binds the polymerase to DNA and acts as a sliding clamp YP_072418.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_072419.1 similar to Yersinia pestis YPO4098 hypothetical protein, 100% identical. YP_072420.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_072421.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_072422.1 similar to Salmonella typhimurium STM3841 inner membrane protein (80% evalue=5.E-35); Escherichia coli JW3682 yidD; Hypothetical protein (80% evalue=5.E-35) YP_072423.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_072424.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_072425.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_072426.1 similar to Yersinia pestis YPO4105 exported protein (97.8% evalue=2.E-42) YP_072427.1 similar to Yersinia pestis YPO4106 hypothetical protein (99.5% evalue=1.E-115) YP_072428.1 similar to Yersinia pestis YPO4107 yieG; Xanthine/uracil permeases family protein (100% evalue=0); Salmonella typhimurium STM3851 yieG; xanthine/uracil permeases family (86.8% evalue=0) YP_072429.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_072430.1 similar to Yersinia pestis YPO4109 amino acid transport system permease (98.8% evalue=1.E-141); Pseudomonas aeruginosa PA2202 polar amino acid transport system permease (64.8% evalue=3.E-79) YP_072431.1 similar to Yersinia pestis YPO4110 ABC transporter permease (100% evalue=1.E-140); Pseudomonas aeruginosa PA2203 polar amino acid transport system permease (65.5% evalue=4.E-74) YP_072432.1 similar to Yersinia pestis YPO4111 periplasmic solute-binding protein (100% evalue=1.E-158); Pseudomonas aeruginosa PA2204 polar amino acid transport system substrate-binding protein (58.3% evalue=6.E-84) YP_072433.1 similar to Yersinia pestis YPO4112 membrane protein (100% evalue=1.E-121); Pseudomonas aeruginosa PA0664 hypothetical protein (37.9% evalue=2.E-10) YP_072434.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_072435.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_072436.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_072437.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_072438.1 similar to Yersinia pestis YPO4117 pstS, phoS; phosphate-binding periplasmic protein (100% evalue=0); Salmonella typhimurium STM3857 pstS; ABC superfamily (bind_prot), high-affinity phosphate transporter (86.9% evalue=1.E-175) YP_072439.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_072440.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_072441.2 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_072442.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_072443.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_072444.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_072445.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_072446.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_072447.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_072448.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_072449.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_072450.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_072451.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs