-- dump date 20140620_141712 -- class Genbank::CDS -- table cds_note -- id note YP_001870457.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001870458.1 binds the polymerase to DNA and acts as a sliding clamp YP_001870459.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001870460.1 negatively supercoils closed circular double-stranded DNA YP_001870461.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_001870462.1 KEGG: yps:YPTB3938 IS1661 DNA-binding protein YP_001870463.1 PFAM: Integrase catalytic region; KEGG: ypa:YPA_3353 transposase for insertion sequence IS1661 YP_001870465.1 PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB3936 multidrug translocase, MFS family YP_001870466.1 KEGG: ypk:y4068 hypothetical protein YP_001870467.1 KEGG: ypp:YPDSF_0045 hypothetical protein YP_001870468.1 KEGG: yps:YPTB3935 hypothetical protein YP_001870469.1 PFAM: transposase mutator type; KEGG: yps:YPTB0012 putative transposase YP_001870470.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_001870471.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001870472.1 PFAM: protein of unknown function DUF1040; KEGG: ypi:YpsIP31758_0018 hypothetical protein YP_001870473.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001870474.1 PFAM: DSBA oxidoreductase; KEGG: ypi:YpsIP31758_0020 thiol:disulfide interchange protein DsbA YP_001870475.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001870476.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001870477.1 PFAM: protein of unknown function DUF414; KEGG: ypi:YpsIP31758_0023 hypothetical protein YP_001870478.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001870479.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_001870480.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_001870481.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001870482.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: ypi:YpsIP31758_0028 GTP-binding protein TypA/BipA YP_001870483.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yps:YPTB0026 phosphatase YP_001870484.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001870485.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001870486.1 TIGRFAM: thioesterase domain protein; PFAM: GCN5-related N-acetyltransferase; Thioesterase putative; KEGG: ypi:YpsIP31758_0032 acetyltransferase, GNAT family/thioesterase domain YP_001870487.1 PFAM: AsmA family protein; KEGG: yps:YPTB0030 possible exported protein YP_001870488.1 TIGRFAM: uracil-xanthine permease; xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypp:YPDSF_3871 membrane permease YP_001870489.1 PFAM: sodium/glutamate symporter; KEGG: ypi:YpsIP31758_0036 sodium/glutamate symporter YP_001870490.1 catalyzes branch migration in Holliday junction intermediates YP_001870491.1 specifically modifies tRNA at position G18 YP_001870492.1 KEGG: ypi:YpsIP31758_0039 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region YP_001870493.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001870494.1 Essential for recycling GMP and indirectly, cGMP YP_001870495.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_001870496.1 PFAM: protein of unknown function UPF0126; KEGG: yps:YPTB0039 hypothetical protein YP_001870498.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ypi:YpsIP31758_0055 conserved hypothetical protein TIGR00255 YP_001870499.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001870500.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001870501.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001870502.1 catalyzes the formation of dUMP from dUTP YP_001870503.2 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001870504.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001870505.1 required for 70S ribosome assembly YP_001870506.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001870507.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001870508.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001870509.1 PFAM: glycosyl transferase family 2; KEGG: ypi:YpsIP31758_0066 glycosyl transferase, group 2 family protein YP_001870510.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001870511.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: ypi:YpsIP31758_0068 lipopolysaccharide heptosyltransferase I YP_001870512.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_001870513.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_001870514.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001870515.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001870516.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: ypi:YpsIP31758_0073 divergent polysaccharide deacetylase YP_001870517.1 PFAM: Peptidase M23; KEGG: yps:YPTB0059 hypothetical protein YP_001870518.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001870519.1 PFAM: Rhodanese domain protein; KEGG: ypi:YpsIP31758_0076 rhodanese domain protein YP_001870520.1 TIGRFAM: glutaredoxin 3; PFAM: glutaredoxin; glutaredoxin 2; KEGG: ypi:YpsIP31758_0077 glutaredoxin 3 YP_001870521.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001870522.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001870523.1 catalyzes the O-acetylation of serine YP_001870524.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: yps:YPTB0067 putative methyltransferase YP_001870525.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: helix-turn-helix- domain containing protein AraC type; Ada metal-binding domain protein; methylguanine DNA methyltransferase ribonuclease domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: yps:YPTB0068 bifunctional regulatory protein/DNA repair protein YP_001870526.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_001870527.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_001870528.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates YP_001870530.1 PFAM: putative transposase YhgA family protein; KEGG: ypi:YpsIP31758_0086 putative transposase YP_001870531.1 KEGG: shw:Sputw3181_2043 transposase, IS4 family protein YP_001870532.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_001870533.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_001870534.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_0090 sulfate ABC transporter, sulfate-binding protein YP_001870536.1 PFAM: extracellular solute-binding protein family 1; KEGG: yps:YPTB0076 possible ABC transporter, periplasmic molybdate binding protein YP_001870537.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: ypi:YpsIP31758_0092 transporter, divalent anion:Na+ symporter (DASS) family YP_001870538.1 TIGRFAM: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase; PFAM: Dimethylmenaquinone methyltransferase; KEGG: ypi:YpsIP31758_0093 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase YP_001870539.1 PFAM: LmbE family protein; KEGG: ypi:YpsIP31758_0094 GlcNAc-PI de-N-acetylase family YP_001870540.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB0080 possible transcriptional regulator YP_001870541.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001870542.1 PFAM: protein of unknown function DUF1454; KEGG: yps:YPTB0082 hypothetical protein YP_001870543.1 PFAM: protein of unknown function DUF805; KEGG: ypi:YpsIP31758_0098 hypothetical protein YP_001870544.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: ypi:YpsIP31758_0099 ferredoxin--NADP reductase YP_001870545.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_001870546.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: ypi:YpsIP31758_0101 glycerol kinase YP_001870547.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: ypi:YpsIP31758_0102 glycerol uptake facilitator protein YP_001870548.1 PFAM: protein of unknown function DUF904; KEGG: ypi:YpsIP31758_0103 hypothetical protein YP_001870549.1 PFAM: ABC transporter transmembrane region; ABC transporter related; peptidase C39 bacteriocin processing; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_0105 bacteriocin ABC transporter, ATP-binding/permease protein YP_001870550.1 PFAM: secretion protein HlyD family protein; KEGG: ypi:YpsIP31758_0106 auxiliary transport protein, membrane fusion protein (MFP) family YP_001870551.1 KEGG: ypi:YpsIP31758_0107 hypothetical protein YP_001870552.1 KEGG: ypi:YpsIP31758_0109 hypothetical protein YP_001870553.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001870554.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_001870555.1 heat shock protein involved in degradation of misfolded proteins YP_001870556.1 heat shock protein involved in degradation of misfolded proteins YP_001870557.1 TIGRFAM: cell division protein FtsN; PFAM: Sporulation domain protein; KEGG: ypi:YpsIP31758_0114 cell division protein FtsN YP_001870558.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_001870560.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001870561.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001870562.1 PFAM: YiaAB two helix domain protein; KEGG: ypi:YpsIP31758_0119 YiaA/B two helix domain protein YP_001870563.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001870564.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_001870565.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001870566.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001870569.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001870570.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001870571.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001870573.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001870574.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001870575.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: yps:YPTB0113 putative TonB dependent receptor protein YP_001870576.1 KEGG: yps:YPTB0114 extracellular heme acquisition hemophore HasA YP_001870577.1 KEGG: yps:YPTB0115 ABC transporter protein, fused permease and ATP binding domains; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase YP_001870578.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: yps:YPTB0116 HlyD family secretion protein YP_001870579.1 TIGRFAM: TonB family protein; KEGG: yps:YPTB0117 putative TonB protein YP_001870580.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001870581.1 TIGRFAM: glutaredoxin-family domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; glutaredoxin; Redoxin domain protein; KEGG: ypi:YpsIP31758_0136 hybrid peroxiredoxin hyPrx5 YP_001870582.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_001870583.1 catalyzes the conversion of NADPH to NADH YP_001870585.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001870586.1 PFAM: protein of unknown function DUF1422; KEGG: ypi:YpsIP31758_0140 hypothetical protein YP_001870587.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001870588.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_001870589.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001870590.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: yps:YPTB0127 ABC transporter, periplasmic ribose/sugar binding protein YP_001870591.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_0148 putative sugar ABC transporter, periplasmic sugar-binding protein YP_001870592.1 PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_0149 putative sugar ABC transporter, permease protein YP_001870593.1 membrane component of a putative sugar ABC transporter system YP_001870594.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_001870595.1 PFAM: protein of unknown function DUF413; KEGG: ypi:YpsIP31758_0152 hypothetical protein YP_001870596.1 KEGG: ypi:YpsIP31758_0153 Mg chelatase-like protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001870597.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001870598.1 KEGG: ypi:YpsIP31758_0155 acetolactate synthase isozyme II small subunit YP_001870599.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001870600.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001870601.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001870602.1 PFAM: protein of unknown function DUF943; KEGG: yps:YPTB0139 hypothetical protein YP_001870603.1 PFAM: protein of unknown function DUF943; KEGG: yps:YPTB0140 hypothetical protein YP_001870604.1 PFAM: protein of unknown function DUF943; KEGG: yps:YPTB0141 hypothetical protein YP_001870605.1 KEGG: yps:YPTB0142 hypothetical protein YP_001870606.1 KEGG: yps:YPTB0143 hypothetical protein YP_001870607.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001870608.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001870609.1 KEGG: ypi:YpsIP31758_0164 colicin/pyocin immunity family protein YP_001870610.1 PFAM: S-type Pyocin domain protein; KEGG: ypg:YpAngola_A0495 S-type pyocin family protein YP_001870611.1 KEGG: yps:YPTB0147 hypothetical protein YP_001870612.1 PFAM: Colicin immunity protein/pyocin immunity protein; KEGG: yps:YPTB0149 putative colicin immunity protein YP_001870613.1 PFAM: HNH endonuclease; KEGG: yps:YPTB0150 putative pyocin S2 (partial) YP_001870614.1 PFAM: Colicin immunity protein/pyocin immunity protein; KEGG: yps:YPTB0151 pyocin S2 immunity protein YP_001870615.1 PFAM: HNH endonuclease; KEGG: yps:YPTB0152 putative pyocin S2 (partial) YP_001870616.1 PFAM: Colicin immunity protein/pyocin immunity protein; KEGG: yps:YPTB0153 colicin immunity protein (E7) YP_001870617.1 KEGG: yps:YPTB0154 probable phage antitermination protein Q YP_001870619.1 KEGG: yps:YPTB0155 hypothetical protein YP_001870620.1 KEGG: hiq:CGSHiGG_04865 hypothetical protein YP_001870621.1 PFAM: Pili assembly chaperone, N-terminal; KEGG: ypp:YPDSF_3496 chaperone protein YP_001870622.1 KEGG: yps:YPTB0157 hypothetical protein YP_001870623.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: yps:YPTB0158 putative outer membrane fimbrial usher porin YP_001870624.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: ypi:YpsIP31758_0170 gram-negative pili assembly chaperone YP_001870625.1 PFAM: Fimbrial protein; KEGG: ypi:YpsIP31758_0171 fimbrial protein YP_001870626.1 PFAM: glutamine cyclotransferase; KEGG: ypi:YpsIP31758_0172 glutamine cyclotransferase YP_001870627.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: ypm:YP_3172 peptidyl-prolyl cis-trans isomerase C YP_001870628.1 KEGG: ypi:YpsIP31758_0174 hypothetical protein YP_001870629.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_001870630.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_001870631.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001870632.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: ypi:YpsIP31758_0179 thioredoxin YP_001870633.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001870634.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase family 4; KEGG: ypi:YpsIP31758_0182 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_001870635.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_001870636.1 PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: ypi:YpsIP31758_0184 UDP-N-acetylglucosamine 2-epimerase YP_001870637.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_001870638.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ypi:YpsIP31758_0186 dTDP-glucose 4,6-dehydratase YP_001870639.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: ypn:YPN_0102 glucose-1-phosphate thymidylyltransferase YP_001870640.1 TIGRFAM: TDP-D-fucosamine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: ypi:YpsIP31758_0188 TDP-D-fucosamine acetyltransferase YP_001870641.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_001870642.1 PFAM: polysaccharide biosynthesis protein; KEGG: yps:YPTB0176 putative PST family O-antigen export (flippase) YP_001870643.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_001870644.1 enterobacterial common antigen polymerase YP_001870645.1 TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF; KEGG: ypi:YpsIP31758_0193 glycosyl transferase, WecB/TagA/CpsF family YP_001870646.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_001870647.1 TIGRFAM: HemY protein; PFAM: HemY domain protein; Tetratricopeptide TPR_2 repeat protein; KEGG: yps:YPTB0181 putative protoheme IX biogenesis protein YP_001870648.1 PFAM: protein of unknown function DUF513 hemX; KEGG: yps:YPTB0182 putative uroporphyrinogen III C-methyltransferase YP_001870649.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_001870650.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001870651.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001870652.1 KEGG: ypi:YpsIP31758_0202 hypothetical protein YP_001870653.1 PFAM: transposase mutator type; KEGG: yps:YPTB3311 putative transposase YP_001870654.1 PFAM: pentapeptide repeat protein; KEGG: ypi:YpsIP31758_0202 hypothetical protein YP_001870655.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_001870656.1 KEGG: yps:YPTB0189 hypothetical protein YP_001870657.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001870658.1 PFAM: protein of unknown function DUF484; KEGG: ypi:YpsIP31758_0206 hypothetical protein YP_001870659.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001870660.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_001870661.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001870662.1 PFAM: regulatory protein TetR; KEGG: yps:YPTB0195 putative TetR-family regulatory protein YP_001870663.1 PFAM: protein of unknown function UPF0261; KEGG: yps:YPTB0196 hypothetical protein YP_001870664.1 KEGG: ypi:YpsIP31758_0212 hypothetical protein YP_001870667.1 responsible for the influx of magnesium ions YP_001870668.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypi:YpsIP31758_0215 RarD protein YP_001870669.1 PFAM: thioesterase superfamily protein; KEGG: ypi:YpsIP31758_0216 thioesterase family protein YP_001870670.1 catalyzes the hydrolysis of phosphatidylcholine YP_001870671.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_001870672.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ypi:YpsIP31758_0219 threonine efflux protein RhtC YP_001870673.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: yps:YPTB0204 homoserine/homoserine lactone efflux protein YP_001870674.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_001870675.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_001870676.1 KEGG: yps:YPTB0207 hypothetical protein YP_001870677.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_001870678.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_001870679.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_001870680.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_001870681.1 KEGG: ypi:YpsIP31758_0230 putative lipoprotein YP_001870682.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: ypi:YpsIP31758_0231 hypothetical protein YP_001870683.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001870684.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_001870685.1 PFAM: YhhN family protein; KEGG: yps:YPTB0216 hypothetical protein YP_001870686.1 PFAM: Domain of unknown function DUF1820; KEGG: ypi:YpsIP31758_0235 hypothetical protein YP_001870687.1 KEGG: ypi:YpsIP31758_0236 hypothetical protein YP_001870688.1 PFAM: protein of unknown function DUF1145; KEGG: ypi:YpsIP31758_0237 hypothetical protein YP_001870689.1 catalyzes the methylation of 16S rRNA at position G966 YP_001870690.1 KEGG: ypg:YpAngola_A0577 cell division protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase YP_001870691.1 putative ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_001870692.1 putative ABC transporter, membrane protein YP_001870693.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001870694.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yps:YPTB0225 putative acetyltransferase YP_001870695.1 PFAM: Extracellular ligand-binding receptor; KEGG: yps:YPTB0226 ABC type periplasmic branched-chain amino acid-binding protein YP_001870696.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_001870697.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001870698.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001870699.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001870700.1 KEGG: yps:YPTB0231 hypothetical protein YP_001870701.1 KEGG: yps:YPTB0232 hypothetical protein YP_001870702.1 KEGG: yps:YPTB0233 hypothetical protein YP_001870703.1 KEGG: yps:YPTB0234 hypothetical protein YP_001870704.1 KEGG: yps:YPTB0235 hypothetical protein YP_001870705.1 KEGG: yps:YPTB0236 hypothetical protein YP_001870706.1 KEGG: yps:YPTB0237 hypothetical protein YP_001870707.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_001870708.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_001870709.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001870710.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_001870711.1 PFAM: Auxin Efflux Carrier; KEGG: yps:YPTB0243 possible malonate permease YP_001870712.1 KEGG: yps:YPTB0244 hypothetical protein YP_001870713.1 PFAM: helix-turn-helix domain protein; protein of unknown function DUF955; KEGG: yps:YPTB0245 hypothetical protein YP_001870714.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypp:YPDSF_3407 membrane protein YP_001870715.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0262 transcriptional regulator MetR YP_001870716.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001870717.1 PFAM: dienelactone hydrolase; BAAT/Acyl-CoA thioester hydrolase; KEGG: ypg:YpAngola_A3647 dienelactone hydrolase family protein YP_001870718.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001870719.1 KEGG: yps:YPTB0251 hypothetical protein YP_001870720.1 PFAM: carbon starvation protein CstA; KEGG: yps:YPTB0252 putative carbon starvation protein YP_001870721.1 KEGG: yps:YPTB0253 hypothetical protein YP_001870722.1 PFAM: protein of unknown function DUF195; KEGG: yps:YPTB0254 putative DNA recombination protein YP_001870723.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001870724.1 PFAM: Sterol-binding domain protein; KEGG: ypp:YPDSF_3397 hypothetical protein YP_001870725.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_001870726.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: ypi:YpsIP31758_0274 twin arginine-targeting protein translocase TatA YP_001870727.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; KEGG: yps:YPTB0259 sec-independent protein translocase protein TatB YP_001870728.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_001870729.1 magnesium dependent; not involved in the Sec-independent protein export system YP_001870730.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001870731.1 KEGG: ypi:YpsIP31758_0279 transcriptional activator RfaH; TIGRFAM: transcriptional activator RfaH; PFAM: NGN domain protein; SMART: KOW domain protein YP_001870732.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_001870733.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001870734.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001870735.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001870736.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001870737.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: ypi:YpsIP31758_0285 hypothetical protein YP_001870738.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: yps:YPTB0270 potassium transporter YP_001870739.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_001870740.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001870741.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001870742.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001870743.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yps:YPTB0275 putative acetyltransferase YP_001870744.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001870745.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001870746.1 Modulates Rho-dependent transcription termination YP_001870747.1 binds directly to 23S ribosomal RNA YP_001870748.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001870749.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001870750.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001870752.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001870753.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001870754.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001870755.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001870756.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_001870757.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: yps:YPTB0288 thiamine biosynthesis protein ThiF YP_001870758.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_001870759.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001870760.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001870761.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_001870762.1 KEGG: ypi:YpsIP31758_3850 hypothetical protein YP_001870763.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001870764.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_001870765.1 PFAM: protein of unknown function DUF416; KEGG: ypi:YpsIP31758_3847 hypothetical protein YP_001870766.1 histone-like DNA-binding protein YP_001870767.1 PFAM: protein of unknown function DUF1481; KEGG: ypi:YpsIP31758_3845 putative lipoprotein YP_001870768.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001870769.1 involved in de novo purine biosynthesis YP_001870771.1 PFAM: transposase IS3/IS911 family protein; KEGG: yps:pYV0018 putative transposase YP_001870772.1 PFAM: Integrase catalytic region; KEGG: yps:YPTB0302 putative transposase YP_001870773.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: yps:YPTB3876 transposase/IS protein YP_001870774.1 PFAM: Integrase catalytic region; Resolvase helix-turn-helix domain protein; KEGG: yps:YPTB3875 putative transposase YP_001870775.1 KEGG: yps:YPTB0305 hypothetical protein YP_001870776.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_001870777.1 PFAM: protein of unknown function DUF485; KEGG: ypi:YpsIP31758_3836 hypothetical protein YP_001870778.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001870779.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system YP_001870780.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: yps:YPTB0310 putative two-component response regulator YP_001870781.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: yps:YPTB0311 two-component sensor/regulator YP_001870782.1 TIGRFAM: type III secretion outer membrane pore, YscC/HrcC family; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: ypi:YpsIP31758_3830 type III secretion outer membrane pore, YscC/HrcC family YP_001870783.1 TIGRFAM: type III secretion apparatus protein, YscD/HrpQ family; KEGG: ypg:YpAngola_A3942 type III secretion apparatus protein, YscD/HrpQ family YP_001870784.1 TIGRFAM: type III secretion system protein, YseE family; KEGG: yps:YPTB0314 hypothetical protein YP_001870785.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ypi:YpsIP31758_3827 transcriptional regulator, AraC family YP_001870786.1 TIGRFAM: type III secretion system needle protein; KEGG: yps:YPTB0316 putative type III secretion apparatus YP_001870787.1 TIGRFAM: type III secretion system protein, SsaH family; KEGG: ypi:YpsIP31758_3825 type III secretion system protein, SsaH family YP_001870788.1 TIGRFAM: type III secretion apparatus protein, YscI/HrpB family; PFAM: type III secretion system YscI/HrpB domain protein; KEGG: yps:YPTB0318 putative type III secretion apparatus YP_001870789.1 TIGRFAM: type III secretion apparatus lipoprotein, YscJ/HrcJ family; PFAM: secretory protein YscJ/FliF family protein; KEGG: ypi:YpsIP31758_3822 type III secretion apparatus lipoprotein, YscJ/HrcJ family YP_001870790.1 KEGG: ypi:YpsIP31758_3821 hypothetical protein YP_001870791.1 TIGRFAM: type III secretion apparatus protein, HrpE/YscL family; KEGG: ypi:YpsIP31758_3820 type III secretion apparatus protein, HrpE/YscL family YP_001870792.1 with SsaC forms part of a protein export system across the inner and outer cell membranes; part of the Salmonella pathogenicity island 2; part of the type III secretion system YP_001870793.1 KEGG: yps:YPTB0323 type III secretion system ATPase; TIGRFAM: ATPase, FliI/YscN family; type III secretion apparatus H+-transporting two-sector ATPase; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase YP_001870794.1 KEGG: yps:YPTB0324 type III secretion system apparatus protein YP_001870795.1 KEGG: ypi:YpsIP31758_3816 hypothetical protein YP_001870796.1 TIGRFAM: type III secretion system apparatus protein YscQ/HrcQ; PFAM: surface presentation of antigens (SPOA) protein; KEGG: ypp:YPDSF_3701 type III secretion system apparatus protein YP_001870797.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_001870798.1 TIGRFAM: type III secretion protein, HrpO family; PFAM: export protein FliQ family 3; KEGG: yps:YPTB0328 putative type III secretion apparatus protein EscS/SsaS/YscS YP_001870799.1 TIGRFAM: type III secretion protein SpaR/YscT/HrcT; PFAM: type III secretion system inner membrane R protein; KEGG: ypi:YpsIP31758_3812 type III secretion apparatus protein SpaR/YscT/HrcT YP_001870800.1 member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli YP_001870801.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: yps:YPTB0331 predicted inner membrane protein YP_001870802.1 PFAM: SirA family protein; KEGG: ypi:YpsIP31758_3809 hypothetical protein YP_001870803.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_3808 substrate-binding transcriptional regulator, LysR family YP_001870804.1 KEGG: ypi:YpsIP31758_3807 putative serine transporter YP_001870805.1 TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: yps:YPTB0335 cystathionine beta-lyase YP_001870806.1 with HmuTU is involved in the transport of hemin YP_001870807.1 PFAM: transport system permease protein; KEGG: ypi:YpsIP31758_3804 hemin ABC transporter, permease protein HmuU YP_001870808.1 PFAM: periplasmic binding protein; KEGG: ypi:YpsIP31758_3803 hemin ABC transporter, periplasmic hemin-binding protein YP_001870809.1 PFAM: Haemin-degrading family protein; KEGG: yps:YPTB0339 possible hemin degradation/transport protein HmuS YP_001870810.1 TIGRFAM: TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; TonB-dependent heme/hemoglobin receptor family protein; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ypi:YpsIP31758_3801 TonB-dependent hemin receptor HmuR YP_001870811.1 KEGG: ypi:YpsIP31758_3800 hemin uptake protein YP_001870812.1 PFAM: NmrA family protein; KEGG: ypi:YpsIP31758_3799 NmrA family protein YP_001870813.1 PFAM: protein of unknown function DUF1008; KEGG: yps:YPTB0343 hypothetical protein YP_001870814.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001870815.1 PFAM: methylenetetrahydrofolate reductase; KEGG: yps:YPTB0345 putative methylenetetrahydrofolate reductase YP_001870816.1 KEGG: ypi:YpsIP31758_3795 hypothetical protein YP_001870817.1 KEGG: ypi:YpsIP31758_3794 hypothetical protein YP_001870818.1 KEGG: ypi:YpsIP31758_3793 hypothetical protein YP_001870819.1 KEGG: ypi:YpsIP31758_3792 hypothetical protein YP_001870820.1 KEGG: ypi:YpsIP31758_3791 hypothetical protein YP_001870821.1 KEGG: yps:YPTB0351 hypothetical protein YP_001870822.1 PFAM: stress protein; KEGG: ypi:YpsIP31758_3789 tellurium resistance protein YP_001870823.1 PFAM: stress protein; KEGG: yps:YPTB0353 putative tellurite resistance protein YP_001870824.1 PFAM: Tellurite resistance TerB; KEGG: ypi:YpsIP31758_3787 tellurite resistance protein YP_001870825.1 PFAM: Integral membrane protein TerC; KEGG: yps:YPTB0355 tellurite resistance protein YP_001870826.1 PFAM: stress protein; KEGG: ypi:YpsIP31758_3785 tellurium resistance protein YP_001870827.1 PFAM: stress protein; KEGG: yps:YPTB0357 tellurium resistance protein YP_001870828.1 KEGG: ypi:YpsIP31758_3783 hypothetical protein YP_001870829.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: yps:YPTB0359 putative outer membrane fimbrial usher protein YP_001870830.1 member of the periplasmic pilus chaperone family of proteins YP_001870831.1 KEGG: ypp:YPDSF_3666 membrane protein YP_001870832.1 KEGG: ypi:YpsIP31758_3779 hypothetical protein YP_001870833.1 PFAM: Carbohydrate-binding family V/XII; Fibronectin type III domain protein; FAD linked oxidase domain protein; Berberine/berberine domain protein; KEGG: ypi:YpsIP31758_3776 putative oxidoreductase, FAD-binding YP_001870834.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; KEGG: yps:YPTB0365 putative autotransporter protein YP_001870835.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_001870836.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001870837.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001870838.1 PFAM: diacylglycerol kinase; KEGG: ypi:YpsIP31758_3771 diacylglycerol kinase YP_001870839.1 Represses a number of genes involved in the response to DNA damage YP_001870840.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_001870841.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase DuS; KEGG: yps:YPTB0372 tRNA-dihydrouridine synthase A YP_001870842.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_001870843.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: yps:YPTB0374 quinone oxidoreductase, NADPH-dependent YP_001870844.1 unwinds double stranded DNA YP_001870845.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001870846.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001870847.1 PFAM: protein of unknown function DUF419; KEGG: ypi:YpsIP31758_3762 hypothetical protein YP_001870848.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_001870849.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_001870850.1 TIGRFAM: L-rhamnose 1-epimerase; PFAM: protein of unknown function DUF718; KEGG: ypi:YpsIP31758_3759 L-rhamnose 1-epimerase YP_001870851.1 TIGRFAM: lactaldehyde reductase; PFAM: iron-containing alcohol dehydrogenase; KEGG: ypi:YpsIP31758_3758 lactaldehyde reductase YP_001870852.1 TIGRFAM: rhamnulose-1-phosphate aldolase; PFAM: class II aldolase/adducin family protein; KEGG: ypg:YpAngola_A0745 rhamnulose-1-phosphate aldolase YP_001870853.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_001870854.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_001870855.1 KEGG: ypg:YpAngola_A0742 hypothetical protein YP_001870856.1 KEGG: ypg:YpAngola_A0741 hypothetical protein YP_001870857.1 activates the expression of the rhaBAD operon and rhaT gene YP_001870858.1 activates the expression of rhaRS in response to L-rhamnose YP_001870859.1 transports L-rhamnose and L-lyxose into the cell YP_001870860.1 KEGG: yps:YPTB0389 hypothetical protein YP_001870861.1 PFAM: IS1 transposase; KEGG: ypp:YPDSF_3635 transposase YP_001870862.1 KEGG: ypi:YpsIP31758_3751 hypothetical protein YP_001870864.1 KEGG: ypg:YpAngola_A0735 hypothetical protein YP_001870865.1 PFAM: peptidase M60 viral enhancin protein; KEGG: ypi:YpsIP31758_3749 viral enhancin protein YP_001870866.1 PFAM: regulatory protein TetR; KEGG: ypk:y0598 putative transcriptional regulator YP_001870867.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_001870868.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: yps:YPTB0397 4Fe-4S ferrodoxin YP_001870869.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: yps:YPTB0398 formate dehydrogenase H YP_001870870.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001870871.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_001870872.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_001870873.1 catalyzes the formation of fumarate from aspartate YP_001870874.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_001870875.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001870876.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001870877.1 KEGG: ypi:YpsIP31758_3674 hypothetical protein YP_001870878.1 TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein; KEGG: ypi:YpsIP31758_3673 iron-sulfur cluster-binding protein, KamA family YP_001870879.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001870880.1 PFAM: small multidrug resistance protein; KEGG: ypp:YPDSF_3618 chaperone YP_001870881.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_001870882.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001870883.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001870884.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001870885.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001870886.1 PFAM: MscS Mechanosensitive ion channel; KEGG: yps:YPTB0415 predicted mechanosensitive channel YP_001870887.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001870888.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001870889.2 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001870890.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: ypi:YpsIP31758_3660 iron-sulfur cluster-binding protein YP_001870891.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: ypp:YPDSF_3606 hypothetical protein YP_001870892.1 possibly involved in cell wall synthesis YP_001870893.1 PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: ypp:YPDSF_3604 N-acetylmuramoyl-L-alanine amidase-family protein YP_001870894.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001870895.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001870896.1 Stimulates the elongation of poly(A) tails YP_001870898.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_001870899.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_001870900.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_001870901.1 KEGG: ypi:YpsIP31758_3649 hypothetical protein YP_001870902.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001870903.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_001870904.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_001870905.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001870906.1 KEGG: ypg:YpAngola_A4005 hypothetical protein YP_001870907.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_001870908.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_001870909.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_001870910.1 KEGG: yps:YPTB0437 hypothetical protein YP_001870911.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001870912.1 KEGG: ypi:YpsIP31758_3638 primosomal replication protein N YP_001870913.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001870914.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001870915.1 KEGG: yps:YPTB0442 hypothetical protein YP_001870916.1 PFAM: Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: ypi:YpsIP31758_3634 opacity-associated protein A family YP_001870917.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_001870918.1 Involved in anaerobic NO protection and iron metabolism YP_001870919.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001870920.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_001870921.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_3629 hypothetical protein YP_001870922.1 PFAM: protein of unknown function DUF1107; KEGG: ypi:YpsIP31758_3628 hypothetical protein YP_001870923.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: ypi:YpsIP31758_3627 CBS/transporter associated domain protein YP_001870924.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001870925.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: ypi:YpsIP31758_3625 surface antigen/outer membrane protein, OMP85 family YP_001870926.1 PFAM: protein of unknown function DUF490; KEGG: ypi:YpsIP31758_3624 hypothetical protein YP_001870927.1 PFAM: AIG2 family protein; KEGG: ypi:YpsIP31758_3623 hypothetical protein YP_001870928.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001870929.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001870930.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: yps:YPTB0457 UDP-N-acetylmuramate:L-Ala-D-Glu-meso-diaminopime late ligase YP_001870931.1 PFAM: protein of unknown function DUF1471; KEGG: ypi:YpsIP31758_3618 hypothetical protein YP_001870932.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001870933.1 oxidizes malate to oxaloacetate YP_001870934.1 KEGG: ypi:YpsIP31758_3615 sugar fermentation stimulation protein B YP_001870935.1 PFAM: MuA-transposase/repressor protein CI DNA-binding; KEGG: ypi:YpsIP31758_3614 hypothetical protein YP_001870936.1 PFAM: Polyprenyl synthetase; KEGG: ypi:YpsIP31758_3613 octaprenyl-diphosphate synthase YP_001870937.1 PFAM: ribosomal protein L21; KEGG: ypi:YpsIP31758_3612 ribosomal protein L21 YP_001870938.1 involved in the peptidyltransferase reaction during translation YP_001870939.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypi:YpsIP31758_3610 integral membrane protein YP_001870940.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001870941.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yps:YPTB0468 sensor protein BasS/PmrB YP_001870942.1 response regulator in two-component regulatory system with BasS YP_001870943.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_001870944.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001870945.1 PFAM: protein of unknown function UPF0044; KEGG: ypi:YpsIP31758_3604 conserved hypothetical protein TIGR00253 YP_001870946.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001870947.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_001870948.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_001870949.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001870950.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: ypi:YpsIP31758_3599 preprotein translocase, SecG subunit YP_001870951.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001870952.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001870953.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001870954.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001870955.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001870956.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001870957.1 PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; SMART: KH domain protein; KEGG: yps:YPTB0484 polynucleotide phosphorylase/polyadenylase YP_001870958.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001870959.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_001870960.1 PFAM: protein of unknown function DUF891; KEGG: yps:YPTB0488 hypothetical protein YP_001870961.1 PFAM: helix-turn-helix domain protein; KEGG: ypi:YpsIP31758_3588 DNA-binding protein YP_001870962.1 KEGG: yps:YPTB2112 hypothetical protein YP_001870963.1 PFAM: Luciferase-like monooxygenase; KEGG: ypi:YpsIP31758_3587 luciferase-like monooxygenase family protein YP_001870964.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: yps:YPTB0491 multidrug efflux protein, membrane fusion (MFP) family YP_001870965.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: yps:YPTB0492 multidrug efflux protein, RND family YP_001870966.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: ypi:YpsIP31758_3584 outer membrane protein OprM YP_001870967.1 PFAM: peptidase U32; KEGG: ypi:YpsIP31758_3583 peptidase, U32 family YP_001870968.1 PFAM: peptidase U32; KEGG: yps:YPTB0495 putative protease YP_001870969.1 PFAM: Sterol-binding domain protein; KEGG: ypp:YPDSF_3287 lipid carrier protein YP_001870970.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ypi:YpsIP31758_3579 acetyltransferase, GNAT family YP_001870971.1 PFAM: Excinuclease ABC C subunit domain protein; KEGG: yps:YPTB0498 hypothetical protein YP_001870972.1 PFAM: Heparinase II/III family protein; KEGG: yps:YPTB0499 hypothetical protein YP_001870973.1 KEGG: yps:YPTB0500 hypothetical protein YP_001870974.1 PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_3575 carbohydrate uptake ABC transporter-1 (CUT1) family, periplasmic carbohydrate-binding protein YP_001870975.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_3574 carbohydrate uptake ABC transporter-1 (CUT1) family, permease protein YP_001870976.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_3573 carbohydrate uptake ABC transporter-1 (CUT1) family, permease protein YP_001870977.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: yps:YPTB0504 putative sugar ABC transporter, ATP-binding protein YP_001870978.1 KEGG: ypi:YpsIP31758_3571 hypothetical protein YP_001870979.1 KEGG: ypi:YpsIP31758_3570 hypothetical protein YP_001870980.1 KEGG: yps:YPTB0507 hypothetical protein YP_001870981.1 required for the use of phosphonates and phosphite as phosphorus sources YP_001870982.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region; KEGG: ypi:YpsIP31758_3567 putative phosphonate metabolism ribose 1,5-bisphosphokinase PhnN YP_001870983.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; Amidohydrolase 3; KEGG: yps:YPTB0510 required for carbon-phosphorous lyase activity, also domain like urease alpha subunit YP_001870984.1 KEGG: yps:YPTB0511 putative ABC phosphonate transporter, ATP binding protein, also putative C-P lyase component; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: AAA ATPase YP_001870985.1 KEGG: yps:YPTB0512 phosphonates transport ATP-binding protein; TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: AAA ATPase YP_001870986.1 PFAM: phosphonate metabolism PhnJ; KEGG: ypi:YpsIP31758_3563 phosphonate metabolism protein PhnJ YP_001870987.1 PFAM: phosphonate metabolism; KEGG: yps:YPTB0514 putative C-P (carbon-phosphorous) lyase component YP_001870988.1 TIGRFAM: phosphonate C-P lyase system protein PhnH; PFAM: phosphonate metabolism; KEGG: yps:YPTB0515 carbon-phosphorus lyase complex subunit YP_001870989.1 TIGRFAM: phosphonate C-P lyase system protein PhnG; PFAM: phosphonate metabolism PhnG; KEGG: yps:YPTB0516 putative C-P (carbon-phosphorous) lyase component YP_001870990.1 may be involved in phosphonate uptake and biodegradation YP_001870991.1 KEGG: ypg:YpAngola_A4033 hypothetical protein YP_001870992.1 KEGG: ypi:YpsIP31758_3557 anaerobic ribonucleoside-triphosphate reductase activating protein YP_001870993.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001870994.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypg:YpAngola_A4036 ABC dipeptide/oligopeptide/nickel transporter, ATP binding protein YP_001870995.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_3554 ABC dipeptide/oligopeptide/nickel transporter, ATP binding protein YP_001870996.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_3553 ABC dipeptide/oligopeptide/nickel transporter, permease protein YP_001870997.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_3552 ABC dipeptide/oligopeptide/nickel transporter, permease protein YP_001870998.1 PFAM: extracellular solute-binding protein family 5; KEGG: ypi:YpsIP31758_3551 ABC dipeptide/oligopeptide/nickel transporter, periplasmic dipeptide/oligopeptide/nickel-binding protein YP_001870999.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_3550 hypothetical protein YP_001871000.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_001871001.1 PFAM: protein of unknown function DUF1260; KEGG: ypi:YpsIP31758_3548 hypothetical protein YP_001871002.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ypi:YpsIP31758_3546 acetyltransferase, GNAT family YP_001871003.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001871004.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001871005.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001871006.1 PFAM: permease YjgP/YjgQ family protein; KEGG: ypi:YpsIP31758_3542 putative permease YP_001871007.1 PFAM: permease YjgP/YjgQ family protein; KEGG: ypi:YpsIP31758_3541 putative permease YP_001871008.1 KEGG: ypi:YpsIP31758_3539 hypothetical protein YP_001871009.1 PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases; KEGG: yps:YPTB0535 putative type I restriction enzyme, R subunit YP_001871010.1 TIGRFAM: PTS system, fructose subfamily, IIA subunit; phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PEP-utilising protein mobile region; KEGG: yps:YPTB0545 general PTS family, enzyme I, phosphohistidine domain YP_001871011.1 KEGG: ypi:YpsIP31758_3527 hypothetical protein YP_001871012.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: ypi:YpsIP31758_3526 antibiotic biosynthesis monooxygenase domain protein YP_001871013.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: ypi:YpsIP31758_3525 DeoC/FbaB aldolase family protein YP_001871014.1 KEGG: yps:YPTB0549 ABC transporter, perplasmic sugar binding protein YP_001871015.1 PFAM: inner-membrane translocator; KEGG: yps:YPTB0550 ABC sugar transporter, permease subunit YP_001871016.1 PFAM: inner-membrane translocator; KEGG: yps:YPTB0551 ABC sugar transporter, permease subunit YP_001871017.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB0552 ABC sugar transporter, fused ATP binding domains YP_001871018.1 PFAM: putative sugar-binding domain protein; KEGG: yps:YPTB0553 putative transcriptional repressor YP_001871019.1 PFAM: carbohydrate kinase FGGY; KEGG: ypi:YpsIP31758_3518 carbohydrate kinase, FGGY family YP_001871020.1 TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: glycosyl transferase family 9; KEGG: ypp:YPDSF_3215 lipopolysaccharide core biosynthesis protein YP_001871021.1 PFAM: O-antigen polymerase; KEGG: yps:YPTB0556 putative O-antigen biosynthesis protein YP_001871022.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; KEGG: yps:YPTB0557 possible conserved cysteine desulfurase YP_001871023.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: yps:YPTB0558 possible acyl-CoA dehydrogenase YP_001871024.1 PFAM: thiamineS protein; KEGG: yps:YPTB0559 hypothetical protein YP_001871025.1 KEGG: yps:YPTB0560 hypothetical protein YP_001871026.1 PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: yps:YPTB0561 putative protein involved in molybdopterin biosynthesis YP_001871027.1 KEGG: ypi:YpsIP31758_3514 hypothetical protein YP_001871028.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ypi:YpsIP31758_3513 efflux transporter, RND family, MFP subunit YP_001871029.1 PFAM: acriflavin resistance protein; KEGG: ypi:YpsIP31758_3512 transporter, AcrB/AcrD/AcrF family YP_001871030.1 KEGG: yps:YPTB0567 hypothetical protein YP_001871031.1 KEGG: yps:YPTB0568 hypothetical protein YP_001871032.1 PFAM: Pectinesterase; KEGG: yps:YPTB0569 pectinesterase A precursor (pectin methylesterase A) YP_001871033.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: yps:YPTB0570 diguanylate cyclase/phosphodiesterase domain 1 YP_001871034.1 PFAM: protein of unknown function DUF1435; KEGG: ypg:YpAngola_A0842 hypothetical protein YP_001871035.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_001871036.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001871037.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_001871038.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001871039.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: ypi:YpsIP31758_3503 osmotically induced periplasmic protein OsmY YP_001871040.1 PFAM: protein of unknown function DUF1328; KEGG: ypi:YpsIP31758_3502 hypothetical protein YP_001871041.1 PFAM: Patatin; KEGG: ypi:YpsIP31758_3501 phospholipase, patatin family YP_001871042.1 PFAM: TatD-related deoxyribonuclease; KEGG: ypg:YpAngola_A0833 hydrolase, TatD family YP_001871043.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: ypi:YpsIP31758_3499 nucleoside transporter, NupC family YP_001871044.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001871045.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001871046.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001871047.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001871048.1 KEGG: ypi:YpsIP31758_3494 putative membrane protein Smp YP_001871049.1 catalyzes the formation of serine from O-phosphoserine YP_001871050.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001871051.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_001871052.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: ypi:YpsIP31758_3490 Fic family protein YP_001871053.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001871054.1 PFAM: OmpA/MotB domain protein; KEGG: yps:YPTB0591 putative OmpA/OmpF family outer membrane porin YP_001871055.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; KEGG: ypg:YpAngola_A0820 putative diguanylate cyclase, GGDEF domain YP_001871056.1 KEGG: ypi:YpsIP31758_3486 hypothetical protein YP_001871057.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: ypi:YpsIP31758_3485 cation-transporting ATPase, P-type, HAD superfamily, subfamily IC YP_001871058.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_001871059.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_001871060.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001871061.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_001871062.1 PFAM: helix-turn-helix- domain containing protein AraC type; transcription activator effector binding; KEGG: ypi:YpsIP31758_3481 right origin-binding protein YP_001871064.1 PFAM: CreA family protein; KEGG: ypi:YpsIP31758_3479 CreA protein YP_001871065.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yps:YPTB0601 DNA-binding response regulator in two-component regulatory system with ArcB or CpxA YP_001871067.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001871068.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001871069.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001871070.1 PFAM: protein of unknown function DUF328; KEGG: ypi:YpsIP31758_3473 hypothetical protein YP_001871071.1 TIGRFAM: transaldolase; PFAM: Transaldolase; KEGG: yps:YPTB0606 transaldolase B YP_001871072.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001871073.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: yps:YPTB0608 MFS family proline/glycine/betaine permease YP_001871074.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yps:YPTB0609 hypothetical protein YP_001871075.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: yps:YPTB0610 hypothetical protein YP_001871076.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001871077.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001871078.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001871079.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_001871080.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001871081.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001871082.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001871083.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001871084.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: ypg:YpAngola_A0788 peptidyl-prolyl cis-trans isomerase, FKBP-type YP_001871085.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001871087.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001871088.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001871089.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001871090.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ypp:YPDSF_3150 LysE type translocator YP_001871091.1 PFAM: protein of unknown function DUF1212; KEGG: yps:YPTB0626 putative transmembrane protein YP_001871092.2 KEGG: ypi:YpsIP31758_3450 hypothetical protein YP_001871093.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_001871094.1 KEGG: yps:YPTB0630 hypothetical protein YP_001871095.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001871096.1 protein associated with Co2+ and Mg2+ efflux YP_001871097.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001871098.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001871099.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_001871100.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_001871101.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001871102.1 PFAM: pseudouridine synthase; KEGG: ypi:YpsIP31758_3439 ribosomal large subunit pseudouridine synthase A YP_001871103.1 KEGG: ypi:YpsIP31758_3438 hypothetical protein YP_001871104.1 KEGG: ypi:YpsIP31758_3437 ImpA domain protein YP_001871105.1 TIGRFAM: type VI secretion protein, VC_A0107 family; PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_3436 hypothetical protein YP_001871106.1 TIGRFAM: type VI secretion protein, EvpB/VC_A0108 family; PFAM: protein of unknown function DUF877; KEGG: yps:YPTB0642 hypothetical protein YP_001871107.1 PFAM: protein of unknown function DUF796; KEGG: ypi:YpsIP31758_3434 hypothetical protein YP_001871108.1 TIGRFAM: type VI secretion system lysozyme-related protein; PFAM: GPW/gp25 family protein; KEGG: ypi:YpsIP31758_3433 hypothetical protein YP_001871109.1 TIGRFAM: type VI secretion protein, VC_A0110 family; PFAM: protein of unknown function DUF879; KEGG: ypi:YpsIP31758_3432 hypothetical protein YP_001871110.1 TIGRFAM: type VI secretion protein, VC_A0111 family; PFAM: protein of unknown function DUF1305; KEGG: yps:YPTB0646 hypothetical protein YP_001871111.1 KEGG: ypi:YpsIP31758_3430 ATPase, AAA family; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001871112.1 TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: yps:YPTB0648 hypothetical protein YP_001871113.1 PFAM: pentapeptide repeat protein; KEGG: yps:YPTB0649 hypothetical protein YP_001871114.1 PFAM: pentapeptide repeat protein; KEGG: ypi:YpsIP31758_3427 pentapeptide repeat protein YP_001871115.1 KEGG: ypi:YpsIP31758_3426 hypothetical protein YP_001871116.1 KEGG: ypi:YpsIP31758_3425 hypothetical protein YP_001871117.1 KEGG: ypi:YpsIP31758_3424 putative lipoprotein YP_001871118.1 TIGRFAM: type VI secretion protein, VC_A0114 family; PFAM: protein of unknown function DUF876; KEGG: ypi:YpsIP31758_3423 hypothetical protein YP_001871119.1 TIGRFAM: type IV / VI secretion system protein, DotU family; PFAM: OmpA/MotB domain protein; KEGG: ypi:YpsIP31758_3422 OmpA domain protein YP_001871120.1 TIGRFAM: type VI secretion protein IcmF; PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: yps:YPTB0656 hypothetical protein YP_001871121.1 KEGG: ypi:YpsIP31758_3420 hypothetical protein YP_001871122.1 KEGG: ypi:YpsIP31758_2425 hypothetical protein YP_001871123.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001871124.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001871125.1 PFAM: SNARE associated Golgi protein; KEGG: ypi:YpsIP31758_3417 hypothetical protein YP_001871126.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_001871127.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_001871128.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_001871130.1 KEGG: yps:YPTB0664 hypothetical protein YP_001871131.1 KEGG: ypg:YpAngola_0115 putative transposase YP_001871132.1 KEGG: yps:YPTB0666 IS1400 transposase protein B YP_001871133.1 activates sgrS under glucose-phosphate stress conditions YP_001871134.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB0668 MFS family transporter, sugar efflux pump YP_001871136.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001871137.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001871138.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001871139.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001871140.1 KEGG: ypm:YP_3642 hypothetical protein YP_001871141.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_001871142.1 PFAM: AMP-dependent synthetase and ligase; KEGG: yps:YPTB0674 putative AMP-binding enzyme-family protein YP_001871143.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_001871144.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001871145.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_001871146.1 PFAM: protein of unknown function DUF1144; KEGG: ypi:YpsIP31758_3397 hypothetical protein YP_001871147.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001871148.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: ypi:YpsIP31758_3395 S-adenosyl-methyltransferase MraW YP_001871149.1 membrane bound cell division protein at septum containing leucine zipper motif YP_001871150.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: ypi:YpsIP31758_3393 penicillin-binding protein YP_001871151.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001871152.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: ypi:YpsIP31758_3391 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_001871153.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001871154.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001871155.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_001871156.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001871157.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001871158.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001871159.1 involved in septum formation YP_001871160.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_001871161.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001871162.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001871163.1 KEGG: ypi:YpsIP31758_3380 hypothetical protein YP_001871164.1 secM translational pause allows for the initiation of secA translation YP_001871165.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001871166.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: ypi:YpsIP31758_3377 mutator MutT protein YP_001871167.1 KEGG: ypa:YPA_3535 hypothetical protein YP_001871168.1 PFAM: transposase IS200-family protein; KEGG: ypi:YpsIP31758_3869 IS1541, transposase YP_001871169.1 PFAM: protein of unknown function DUF329; KEGG: ypi:YpsIP31758_3376 zinc-binding protein YacG YP_001871170.1 PFAM: protein of unknown function DUF1342; KEGG: yps:YPTB0701 hypothetical protein YP_001871171.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001871172.1 KEGG: ypm:YP_0255 hypothetical protein YP_001871173.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_001871174.1 PFAM: transposase mutator type; KEGG: yps:YPTB3311 putative transposase YP_001871175.1 PFAM: type II secretion system protein; KEGG: ypi:YpsIP31758_3372 putative protein transport protein HofC YP_001871176.1 PFAM: type II secretion system protein E; KEGG: yps:YPTB0706 hypothetical protein YP_001871177.1 KEGG: ypi:YpsIP31758_3370 type IV pilin PilA YP_001871178.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001871179.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: ypi:YpsIP31758_3368 N-acetyl-anhydromuramyl-L-alanine amidase YP_001871180.1 involved in regulation of beta-lactamase; putative signaling protein YP_001871181.1 PFAM: amino acid permease-associated region; KEGG: yps:YPTB0711 APC family, aromatic amino acid transporter YP_001871183.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001871184.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001871185.1 TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: yps:YPTB0714 dihydrolipoamide acetyltransferase YP_001871186.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001871187.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001871188.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_3358 hypothetical protein YP_001871189.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: yps:YPTB0718 hypothetical protein YP_001871190.1 KEGG: ypg:YpAngola_A1025 hypothetical protein YP_001871191.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_001871192.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001871193.1 KEGG: ypi:YpsIP31758_3353 hypothetical protein YP_001871194.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_001871195.1 TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: ypi:YpsIP31758_3351 hypoxanthine phosphoribosyltransferase YP_001871196.1 PFAM: carbonic anhydrase; KEGG: ypg:YpAngola_A1018 carbonic anhydrase YP_001871197.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_3349 ABC transporter, ATP-binding protein YP_001871198.1 PFAM: ABC-2 type transporter; KEGG: yps:YPTB0726 putative ABC type drug efflux permease protein YP_001871199.1 PFAM: polysaccharide deacetylase; KEGG: ypi:YpsIP31758_3346 polysaccharide deacetylase family protein YP_001871200.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001871201.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001871202.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001871203.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: ypi:YpsIP31758_3341 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_001871204.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_001871205.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_001871206.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: ypi:YpsIP31758_3338 RNA polymerase-binding protein DksA YP_001871207.1 Regulatory factor involved in maltose metabolism YP_001871208.1 TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: ypi:YpsIP31758_3336 2'-5' RNA ligase YP_001871209.1 KEGG: cph:Cpha266_2219 hypothetical protein YP_001871210.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_001871211.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_001871212.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_001871213.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_001871214.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_001871215.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001871217.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_001871218.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001871219.1 PFAM: protein of unknown function UPF0126; KEGG: ypi:YpsIP31758_3327 hypothetical protein YP_001871220.1 solute binding component of the vitamin B12 transport system BtuCDF YP_001871221.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001871222.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_001871223.1 protease Do; required at high temperature; degrades damaged proteins YP_001871224.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001871225.1 KEGG: ypi:YpsIP31758_3320 hypothetical protein YP_001871226.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_001871227.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001871228.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001871229.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001871230.1 PFAM: superoxide dismutase copper/zinc binding; KEGG: yps:YPTB0756 superoxide dismutase precursor (Cu-Zn) YP_001871231.1 PFAM: Radical SAM domain protein; KEGG: ypi:YpsIP31758_3313 radical SAM domain protein YP_001871232.1 TIGRFAM: queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: ypi:YpsIP31758_3312 putative 6-pyruvoyl tetrahydrobiopterin synthase YP_001871233.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_001871234.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001871235.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001871236.1 PFAM: protein of unknown function UPF0150; KEGG: ypi:YpsIP31758_3308 hypothetical protein YP_001871237.1 PFAM: YcfA family protein; KEGG: ypi:YpsIP31758_3307 hypothetical protein YP_001871238.1 KEGG: ypi:YpsIP31758_3306 hypothetical protein YP_001871239.1 TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: yps:YPTB0764 siroheme synthase, catalyses four separate reactions required for the transformation of uroporphyrinogen III into siroheme YP_001871240.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001871241.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_001871242.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_001871243.1 KEGG: ypi:YpsIP31758_3301 hypothetical protein YP_001871244.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_001871245.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001871246.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001871247.1 catalyzes the modification of U13 in tRNA(Glu) YP_001871248.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001871249.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_001871250.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_001871251.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_001871252.1 This protein performs the mismatch recognition step during the DNA repair process YP_001871253.1 KEGG: ypi:YpsIP31758_3290 hypothetical protein YP_001871254.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_001871255.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ypi:YpsIP31758_3288 oxidoreductase, zinc-binding dehydrogenase family YP_001871256.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: ypi:YpsIP31758_3287 oxidoreductase, short chain dehydrogenase/reductase family protein YP_001871257.1 PFAM: Dak kinase; KEGG: ypg:YpAngola_A0949 dihydroxyacetone kinase family protein YP_001871258.1 TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase; KEGG: yps:YPTB0783 putative dihydroxyacetone kinase protein YP_001871259.1 PFAM: putative sugar-binding domain protein; KEGG: ypg:YpAngola_A0947 putative sugar-binding domain protein YP_001871260.1 TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: ypi:YpsIP31758_3282 arsenical pump membrane protein YP_001871261.1 regulates the expression of of the arsRBC involved in resistance to arsenic YP_001871262.1 KEGG: yps:YPTB0787 hypothetical protein YP_001871263.1 KEGG: ypi:YpsIP31758_3280 hypothetical protein YP_001871264.1 PFAM: extracellular solute-binding protein family 3; KEGG: yps:YPTB0789 probable ABC transporter, perplasmic amino acid binding protein YP_001871265.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: ypi:YpsIP31758_3278 cytochrome c peroxidase YP_001871266.1 KEGG: ypi:YpsIP31758_3277 hypothetical protein YP_001871267.1 KEGG: yps:YPTB0791 hypothetical protein YP_001871268.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ypi:YpsIP31758_3276 TonB-dependent receptor YP_001871269.1 PFAM: ShET2 enterotoxin domain protein; KEGG: yps:YPTB0793 hypothetical protein YP_001871270.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: ypi:YpsIP31758_3273 methionine aminopeptidase, type I YP_001871271.1 KEGG: ypi:YpsIP31758_3272 hypothetical protein YP_001871272.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: yps:YPTB0796 fumarase A (fumarate hydratase class I), aerobic isozyme YP_001871273.1 PFAM: carbohydrate kinase FGGY; KEGG: ypi:YpsIP31758_3270 cryptic L-xylulose kinase YP_001871274.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_001871275.1 PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_3268 carbohydrate uptake ABC transporter 2 (CUT2) family, permease protein YP_001871276.1 PFAM: inner-membrane translocator; KEGG: yps:YPTB0800 putative ABC sugar transporter, permease subunit YP_001871277.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_3266 carbohydrate uptake ABC transporter 2 (CUT2) family, ATP-binding protein YP_001871278.1 KEGG: ypi:YpsIP31758_3265 carbohydrate uptake ABC transporter 2 (CUT2) family, periplasmic carbohydrate-binding protein YP_001871279.1 PFAM: regulatory protein DeoR; KEGG: yps:YPTB0803 putative DeoR-family sugar uptake regulatory protein YP_001871280.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001871281.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: yps:YPTB0805 anaerobic dimethyl sulfoxide reductase, subunit A YP_001871282.1 TIGRFAM: dimethylsulfoxide reductase, chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ypi:YpsIP31758_3260 anaerobic dimethyl sulfoxide reductase, B subunit YP_001871283.1 PFAM: DMSO reductase anchor subunit (DmsC); KEGG: ypg:YpAngola_A0920 anaerobic dimethyl sulfoxide reductase, C subunit YP_001871284.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane YP_001871285.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm YP_001871286.1 PFAM: cytochrome b562; KEGG: ypi:YpsIP31758_3255 cytochrome b562 YP_001871287.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: yps:YPTB0811 catalase; hydroperoxidase HPI(I) YP_001871288.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_3253 ribose ABC transporter, periplasmic ribose-binding protein YP_001871289.1 KEGG: ypi:YpsIP31758_3252 putative lipoprotein YP_001871290.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB0814 ABC sugar transporter, fused ATP-binding domains YP_001871291.1 PFAM: inner-membrane translocator; KEGG: yps:YPTB0815 ABC sugar transporter, permease subunit YP_001871292.1 PFAM: Transketolase domain protein; KEGG: yps:YPTB0816 putative N-terminal region of transketolase YP_001871293.1 PFAM: Transketolase central region; Transketolase domain protein; KEGG: ypi:YpsIP31758_3248 putative transketolase, C-terminal subunit YP_001871294.1 PFAM: carbohydrate kinase FGGY; KEGG: yps:YPTB0818 putative glycerol kinase 2 YP_001871295.1 PFAM: L-fucose isomerase-like-like; KEGG: yps:YPTB0819 hypothetical protein YP_001871296.1 KEGG: ypi:YpsIP31758_3244 hypothetical protein YP_001871297.1 PFAM: putative sugar-binding domain protein; KEGG: ypi:YpsIP31758_3245 putative sugar-binding domain protein YP_001871298.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_3242 transporter, major facilitator family YP_001871299.1 PFAM: CinA domain protein; KEGG: ypi:YpsIP31758_3241 competence/damage-inducible protein CinA domain protein YP_001871300.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001871301.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001871302.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001871303.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001871304.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_001871305.1 KEGG: ypi:YpsIP31758_3235 hypothetical protein YP_001871306.1 involved in the first step of glutathione biosynthesis YP_001871307.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001871308.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: ypp:YPDSF_3062 membrane protein YP_001871309.1 PFAM: cytochrome c assembly protein; KEGG: ypi:YpsIP31758_3231 putative cytochrome c assembly protein YP_001871310.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001871311.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001871312.1 Essential for efficient processing of 16S rRNA YP_001871313.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001871314.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001871315.1 PFAM: protein of unknown function DUF481; KEGG: ypi:YpsIP31758_3223 hypothetical protein YP_001871316.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_001871317.1 unknown function; when overproduced it confers drug-resistance YP_001871318.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001871319.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001871320.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: yps:YPTB3876 transposase/IS protein YP_001871321.1 PFAM: Integrase catalytic region; Resolvase helix-turn-helix domain protein; KEGG: yps:YPTB3875 putative transposase YP_001871322.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_001871323.1 KEGG: ypg:YpAngola_A3480 hypothetical protein YP_001871324.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: ypi:YpsIP31758_3216 ribosomal subunit interface protein YP_001871325.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_001871326.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_001871327.1 PFAM: protein of unknown function DUF152; KEGG: ypi:YpsIP31758_3213 conserved hypothetical protein TIGR00726 YP_001871328.1 KEGG: ypi:YpsIP31758_3212 chaperone ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001871329.1 KEGG: ypi:YpsIP31758_3208 putative lipoprotein YP_001871330.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001871331.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: ypi:YpsIP31758_3206 putative acyl-CoA synthetase YP_001871332.1 PFAM: DTW domain containing protein; KEGG: ypg:YpAngola_A3464 DTW domain protein YP_001871333.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: ypg:YpAngola_A3463 thioredoxin 2 YP_001871334.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: ypp:YPDSF_2905 tRNA/rRNA methyltransferase YP_001871335.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_3202 multidrug resistance protein B YP_001871336.1 TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: ypi:YpsIP31758_3201 multidrug resistance protein A YP_001871337.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_001871338.1 KEGG: ypi:YpsIP31758_3199 hypothetical protein YP_001871339.1 PFAM: AzlC family protein; KEGG: ypi:YpsIP31758_3198 putative azaleucine resistance protein AzlC YP_001871340.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_3197 transporter, major facilitator family YP_001871341.1 KEGG: yps:YPTB0861 hypothetical protein YP_001871342.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001871343.1 KEGG: ypi:YpsIP31758_3193 hypothetical protein YP_001871344.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: ypi:YpsIP31758_3191 transcriptional regulator, RpiR family YP_001871345.1 PFAM: extracellular solute-binding protein family 3; KEGG: ypi:YpsIP31758_3190 amino acid ABC transporter, periplasmic amino acid-binding protein YP_001871346.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_3189 amino acid ABC transporter, permease protein YP_001871347.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_3188 amino acid ABC transporter, permease protein YP_001871348.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_3187 amino acid ABC transporter, ATP-binding protein YP_001871349.1 PFAM: aminotransferase class V; KEGG: yps:YPTB0870 aminotransferase, class V YP_001871350.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001871351.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: yps:YPTB0872 hypothetical protein YP_001871352.1 catalyzes the transfer of an amino moiety YP_001871353.1 catalyzes the formation of diketo methylthiopentyl phosphate from methylribulose phosphate in the methionine salvage pathway YP_001871354.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yps:YPTB0875 enolase-phosphatase E-1 YP_001871355.1 PFAM: Acireductone dioxygenase ARD; KEGG: ypi:YpsIP31758_3180 dioxygenase, ARD/ARD' family YP_001871356.1 TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related; KEGG: yps:YPTB0877 putative translation initiation factor EIF-2B, GDP-GTP exchange factor (alpha subunit) YP_001871357.1 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway YP_001871359.1 PFAM: Polypeptide-transport-associated domain protein ShlB-type; KEGG: yps:YPTB0879 TPS secretion family, afimbrail adhesion, hemopexin utilization YP_001871360.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: filamentous haemagglutinin domain protein; KEGG: ypp:YPDSF_2876 adhesin YP_001871361.1 involved in the adherence of host cells; KEGG: yps:YPTB0881 putative accessory processing protein; involved in the adherence of host cells YP_001871362.1 KEGG: ypi:YpsIP31758_3172 hypothetical protein YP_001871363.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001871364.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_001871365.1 PFAM: glutamine amidotransferase class-II; KEGG: yps:YPTB0885 hypothetical protein YP_001871366.1 PFAM: protein of unknown function DUF949; KEGG: ypi:YpsIP31758_3169 hypothetical protein YP_001871367.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001871368.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001871369.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001871370.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001871371.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001871372.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001871373.1 PFAM: ApbE family lipoprotein; KEGG: ypp:YPDSF_2861 thiamine biosynthesis lipoprotein YP_001871374.1 PFAM: protein of unknown function DUF539; KEGG: ypi:YpsIP31758_3159 hypothetical protein YP_001871375.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: yps:YPTB0895 hypothetical protein YP_001871376.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001871377.1 TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ypi:YpsIP31758_3156 aminoacyl-histidine dipeptidase YP_001871378.1 KEGG: ypi:YpsIP31758_3155 transcriptional regulator, LysR family YP_001871379.1 PFAM: PKD domain containing protein; chitin-binding domain 3 protein; KEGG: ypi:YpsIP31758_3154 chitin binding domain protein YP_001871380.1 KEGG: yps:YPTB0900 possible holin protein YP_001871381.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_001871382.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_001871383.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_001871384.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001871385.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001871386.1 PFAM: type IV pilus assembly PilZ; YcgR family protein; KEGG: yps:YPTB0906 hypothetical protein YP_001871387.1 KEGG: ypi:YpsIP31758_3147 hypothetical protein YP_001871388.1 PFAM: Methyltransferase type 11; KEGG: ypi:YpsIP31758_3145 hypothetical protein YP_001871389.1 KEGG: ypi:YpsIP31758_3144 putative methyltransferase YP_001871390.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001871391.1 PFAM: protein of unknown function DUF1255; KEGG: ypi:YpsIP31758_3142 hypothetical protein YP_001871392.1 Required for efficient pilin antigenic variation YP_001871393.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_001871394.1 PFAM: SMC domain protein; KEGG: yps:YPTB0915 putative ATP-dependent dsDNA exonuclease YP_001871395.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_001871396.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ypi:YpsIP31758_3136 phosphate regulon transcriptional regulatory protein PhoB YP_001871397.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_001871398.1 TIGRFAM: phosphate binding protein; KEGG: ypi:YpsIP31758_3134 phosphate-binding protein YP_001871399.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: yps:YPTB0920 LIVCS family, branched chain amino acid transporter system II (LIV-II) YP_001871400.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_001871401.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: yps:YPTB0922 maltodextrin glucosidase YP_001871402.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: yps:YPTB0923 short chain dehydrogenase YP_001871403.1 TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: yps:YPTB0924 gamma-glutamyltranspeptidase precursor YP_001871404.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: ypi:YpsIP31758_3126 antioxidant, AhpC/TSA family YP_001871405.1 PFAM: protein of unknown function DUF479; KEGG: ypg:YpAngola_A3386 acyl carrier protein phosphodiesterase YP_001871406.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001871407.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001871408.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001871409.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001871410.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001871411.1 KEGG: yps:YPTB0932 hypothetical protein YP_001871412.1 PFAM: ATP-cone domain protein; KEGG: ypi:YpsIP31758_3118 transcriptional regulator, NrdR family YP_001871413.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil YP_001871414.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001871415.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001871416.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001871417.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_001871418.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001871419.1 PFAM: Polyprenyl synthetase; KEGG: ypi:YpsIP31758_3111 geranyltranstransferase YP_001871420.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001871421.1 KEGG: ypi:YpsIP31758_3109 hypothetical protein YP_001871422.1 Required for the synthesis of the thiazole moiety YP_001871423.1 TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: ypi:YpsIP31758_3107 DJ-1 family protein YP_001871424.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_001871425.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001871426.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_3103 transporter, major facilitator family YP_001871427.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001871428.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: ypi:YpsIP31758_3101 cytochrome o ubiquinol oxidase, subunit IV YP_001871429.1 TIGRFAM: cytochrome o ubiquinol oxidase, subunit III; PFAM: cytochrome c oxidase subunit III; KEGG: ypi:YpsIP31758_3100 cytochrome o ubiquinol oxidase, subunit III YP_001871430.1 TIGRFAM: cytochrome o ubiquinol oxidase, subunit I; PFAM: cytochrome c oxidase subunit I; KEGG: ypi:YpsIP31758_3099 cytochrome o ubiquinol oxidase, subunit I YP_001871431.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; COX aromatic rich domain protein; KEGG: ypi:YpsIP31758_3098 cytochrome o ubiquinol oxidase, subunit II YP_001871432.1 PFAM: protein of unknown function DUF1384; KEGG: yps:YPTB0953 hypothetical protein YP_001871433.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_001871434.1 PFAM: Uncharacterized lipoprotein; KEGG: ypi:YpsIP31758_3095 putative lipoprotein YP_001871435.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_001871436.1 KEGG: yps:YPTB0957 hypothetical protein YP_001871437.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001871438.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001871439.1 binds and unfolds substrates as part of the ClpXP protease YP_001871440.1 KEGG: ypi:YpsIP31758_3090 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16 lon domain protein; AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001871441.1 histone-like DNA-binding protein YP_001871442.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: ypi:YpsIP31758_3088 peptidyl-prolyl cis-trans isomerase YP_001871443.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: yps:YPTB0964 possible DNA uptake protein ComEA related protein YP_001871444.1 PFAM: thioesterase superfamily protein; KEGG: ypi:YpsIP31758_3086 thioesterase family protein YP_001871445.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_001871446.1 PFAM: extracellular solute-binding protein family 5; KEGG: ypi:YpsIP31758_3084 putative ABC transporter, periplasmic binding protein YP_001871447.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: Haloacid dehalogenase domain protein hydrolase; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase type 3; KEGG: ypi:YpsIP31758_3083 HAD hydrolase, IIB family YP_001871448.1 PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: yps:YPTB0969 putative pyridoxal-phosphate dependent protein YP_001871449.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: ypi:YpsIP31758_3081 transcriptional regulator, AsnC family YP_001871450.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_3080 multidrug ABC transporter, permease protein/ATP-binding protein MdlA YP_001871451.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB0972 putative multidrug transporter membrane\ATP-binding components YP_001871452.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_001871453.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: ypi:YpsIP31758_3077 ammonium transporter YP_001871455.1 TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; KEGG: yps:YPTB0975 acyl-CoA thioesterase II YP_001871456.1 KEGG: ypi:YpsIP31758_3075 putative lipoprotein YP_001871457.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: yps:YPTB0977 putative 6-O-methylguanine DNA methyltransferase family protein YP_001871458.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_001871459.1 KEGG: ypi:YpsIP31758_3072 hypothetical protein YP_001871460.1 KEGG: yps:YPTB0980 hypothetical protein YP_001871461.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_001871462.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001871463.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: yps:YPTB0983 RND family, acridine/multidrug efflux pump YP_001871464.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ypi:YpsIP31758_3067 acriflavine resistance protein A YP_001871465.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_001871466.1 PFAM: DsrE family protein; KEGG: ypi:YpsIP31758_3065 DsrE family protein YP_001871467.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_001871468.1 KEGG: ypi:YpsIP31758_3063 hypothetical protein YP_001871469.1 PFAM: Primosomal replication priB and priC; KEGG: yps:YPTB0989 putative primosomal replication protein N'' YP_001871470.1 KEGG: ypi:YpsIP31758_3061 hypothetical protein YP_001871471.1 KEGG: ypg:YpAngola_A2887 hypothetical protein YP_001871472.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001871473.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001871474.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_3058 conserved hypothetical protein TIGR00103 YP_001871475.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001871476.1 molecular chaperone YP_001871477.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001871478.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001871479.1 catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose YP_001871480.1 TIGRFAM: glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: ypp:YPDSF_2751 glucose-1-phosphate cytidylyltransferase YP_001871481.1 TIGRFAM: CDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: yps:YPTB1000 CDP-glucose 4,6-dehydratase YP_001871482.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: ypp:YPDSF_2749 putative CDP-4-keto-6-deoxy-D-glucose-3-dehydratase YP_001871483.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: ypi:YpsIP31758_3048 CDP-paratose synthetase YP_001871484.1 KEGG: ypi:YpsIP31758_3047 O-antigen synthesis protein WbyH YP_001871485.1 KEGG: ypk:y1074 O-unit flippase-like protein YP_001871486.1 PFAM: glycosyl transferase family 2; KEGG: ypi:YpsIP31758_3045 glycosyl transferase, group 2 family protein YP_001871488.1 PFAM: glycosyl transferase group 1; KEGG: rpb:RPB_1547 glycosyl transferase, group 1 YP_001871489.1 KEGG: fta:FTA_0778 hypothetical membrane protein YP_001871490.1 PFAM: glycosyl transferase group 1; KEGG: reh:H16_A2889 glycosyltransferase, probably involved in lipopolysaccharide biosynthesis YP_001871491.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: bpd:BURPS668_3245 NAD-dependent epimerase/dehydratase family protein YP_001871492.1 PFAM: NAD-dependent epimerase/dehydratase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: cjr:CJE1611 GDP-mannose 4,6-dehydratase YP_001871493.1 PFAM: GHMP kinase; GHMP kinase domain protein; KEGG: plu:plu4822 WblW protein YP_001871494.1 TIGRFAM: phosphoheptose isomerase; KEGG: plu:plu4823 WblX protein YP_001871495.1 PFAM: Nucleotidyl transferase; KEGG: plu:plu4824 WblY protein YP_001871496.1 TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Polynucleotide kinase 3 phosphatase central region; KEGG: plu:plu4825 WblZ protein YP_001871498.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake YP_001871499.1 PFAM: PfkB domain protein; KEGG: ypi:YpsIP31758_3035 inosine-guanosine kinase YP_001871500.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_001871501.1 PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB1017 MFS cationic antimicrobial peptides (CAMPs) efflux/K+ antiporter, RosA subunit YP_001871502.1 KEGG: ypi:YpsIP31758_3031 hypothetical protein YP_001871503.1 KEGG: ypi:YpsIP31758_3619 hypothetical protein YP_001871504.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: yps:YPTB1020 hypothetical protein YP_001871505.1 PFAM: GumN family protein; KEGG: yps:YPTB1021 hypothetical protein YP_001871506.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: yps:YPTB1022 copper transporter YP_001871507.1 TIGRFAM: Cu(I)-responsive transcriptional regulator; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: yps:YPTB1023 putative MerR family copper regulatory protein, CueR YP_001871508.1 PFAM: protein of unknown function DUF107; KEGG: ypi:YpsIP31758_3025 nodulation efficiency protein D YP_001871509.1 PFAM: band 7 protein; KEGG: ypi:YpsIP31758_3024 SPFH/band 7 family protein YP_001871510.1 PFAM: Thioredoxin domain; KEGG: yps:YPTB1026 putative thioredoxin YP_001871511.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypi:YpsIP31758_3022 oxidoreductase, short chain dehydrogenase/reductase family protein YP_001871512.1 PFAM: lipolytic protein G-D-S-L family; KEGG: ypi:YpsIP31758_3021 GDSL-like lipase/acylhydrolase family protein YP_001871513.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_3020 putatitve ABC transporter, ATP-binding protein YP_001871514.1 PFAM: protein of unknown function DUF214; KEGG: yps:YPTB1030 putative permease YP_001871515.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001871516.1 TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: ypi:YpsIP31758_3017 phosphoribosylaminoimidazole carboxylase, catalytic subunit YP_001871517.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001871518.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: ypi:YpsIP31758_3015 peptidyl-prolyl cis-trans isomerase B YP_001871519.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001871520.1 KEGG: ypi:YpsIP31758_3013 hypothetical protein YP_001871521.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001871522.1 KEGG: yps:YPTB1039 hypothetical protein YP_001871523.1 KEGG: yps:YPTB1040 hypothetical protein YP_001871524.1 KEGG: ypi:YpsIP31758_3010 hypothetical protein YP_001871525.1 KEGG: yps:YPTB1043 hypothetical protein YP_001871526.1 KEGG: ypi:YpsIP31758_3008 hypothetical protein YP_001871527.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: yps:YPTB1044 putative CDP-alcohol phosphatidyltransferase YP_001871528.1 PFAM: phosphatidate cytidylyltransferase; KEGG: ypi:YpsIP31758_3005 phosphatidate cytidylyltransferase YP_001871529.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: ypi:YpsIP31758_3004 putative 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_001871530.1 PFAM: alpha/beta hydrolase fold; KEGG: yps:YPTB1047 hypothetical protein YP_001871531.1 PFAM: phosphoesterase PA-phosphatase related; Dual specificity protein phosphatase; KEGG: yps:YPTB1048 putative dual specificity phosphatase YP_001871532.1 KEGG: ypg:YpAngola_A1292 hypothetical protein YP_001871533.1 KEGG: yps:YPTB1050 hypothetical protein YP_001871534.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB1051 putative LysR-family transcriptional regulatory protein YP_001871535.1 PFAM: aldo/keto reductase; KEGG: ypi:YpsIP31758_2999 oxidoreductase, aldo/keto reductase family YP_001871536.1 PFAM: aldo/keto reductase; KEGG: ypi:YpsIP31758_2998 oxidoreductase, aldo/keto reductase family YP_001871537.1 KEGG: ypi:YpsIP31758_2997 hypothetical protein YP_001871539.1 KEGG: yps:YPTB1054 hypothetical protein YP_001871540.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: ypi:YpsIP31758_2994 glycosyl hydrolase, family 3 YP_001871541.1 KEGG: ypi:YpsIP31758_2993 hypothetical protein YP_001871542.1 KEGG: yps:YPTB1057 hypothetical protein YP_001871544.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_001871545.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: yps:YPTB1059 hypothetical protein YP_001871546.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: yps:YPTB1061 putative pertactin family virulence factor/autotransporter YP_001871547.1 KEGG: yps:YPTB1062 hypothetical protein YP_001871548.1 KEGG: yps:YPTB1063 hypothetical protein YP_001871549.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: ypi:YpsIP31758_2983 hypothetical protein YP_001871550.1 PFAM: protein of unknown function DUF1240; KEGG: yps:YPTB1065 hypothetical protein YP_001871551.1 PFAM: protein of unknown function DUF1240; KEGG: ypn:YPN_1051 hypothetical protein YP_001871552.1 KEGG: yps:YPTB1066 hypothetical protein YP_001871554.1 KEGG: ypi:YpsIP31758_2981 sugar fermentation stimulation protein B YP_001871555.1 TIGRFAM: penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; Penicillin-binding domain protein; KEGG: ypi:YpsIP31758_2980 penicillin-binding protein 1C YP_001871556.1 PFAM: alpha-2-macroglobulin domain protein; alpha-2-macroglobulin domain protein 2; KEGG: ypp:YPDSF_2679 membrane protein YP_001871558.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: yps:YPTB1070 hypothetical protein YP_001871559.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: ypi:YpsIP31758_2977 methylmalonate-semialdehyde dehydrogenase YP_001871560.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB1072 putative thiamine pyrophosphate-dependent protein YP_001871561.1 KEGG: ypi:YpsIP31758_2975 hypothetical protein YP_001871562.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: yps:YPTB1073 putative myo-inositol 2-dehydrogenase YP_001871563.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_2973 ribose ABC transporter, periplasmic ribose-binding protein YP_001871564.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1075 ABC type sugar transporter with fused ATP-binding domains YP_001871565.1 PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_2971 ribose ABC transporter, permease protein YP_001871566.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: yps:YPTB1077 hypothetical protein YP_001871567.1 PFAM: PfkB domain protein; KEGG: yps:YPTB1078 putative carbohydrate kinase YP_001871568.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: ypg:YpAngola_A1869 AP endonuclease, family 2 YP_001871569.1 PFAM: Myo-inositol catabolism IolB domain protein; KEGG: ypi:YpsIP31758_2967 putative myo-inositol catabolism protein IolB YP_001871570.1 KEGG: ypk:y1156 hypothetical protein YP_001871571.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1082 putative ABC transport protein with fused ATP binding and permease domains YP_001871572.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: ypi:YpsIP31758_2964 antibiotic biosynthesis monooxygenase domain protein YP_001871573.1 KEGG: ypi:YpsIP31758_2963 hypothetical protein YP_001871574.1 KEGG: ypi:YpsIP31758_2961 hypothetical protein YP_001871575.1 PFAM: regulatory protein LuxR; KEGG: ypi:YpsIP31758_2960 transcriptional regulator, LuxR family YP_001871576.1 PFAM: Cold-shock protein DNA-binding; KEGG: ypi:YpsIP31758_2959 cold-shock DNA-binding domain protein YP_001871577.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_001871578.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001871579.1 KEGG: ypp:YPDSF_2657 hypothetical protein YP_001871580.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001871581.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001871582.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001871583.1 PFAM: protein of unknown function DUF493; KEGG: ypi:YpsIP31758_2953 hypothetical protein YP_001871584.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_001871585.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: ypi:YpsIP31758_2951 rare lipoprotein A/sporulation and cell division repeat protein YP_001871586.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: ypi:YpsIP31758_2950 rod shape-determining protein RodA YP_001871587.1 TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: yps:YPTB1097 penicillin-binding protein 2 YP_001871588.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001871589.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: ypi:YpsIP31758_2947 iojap-related protein YP_001871590.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_001871591.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001871592.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_001871593.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001871594.1 PFAM: protein of unknown function DUF1451; KEGG: ypi:YpsIP31758_2924 hypothetical protein YP_001871595.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_2923 glutamate/aspartate ABC transporter, ATP-binding protein YP_001871596.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2922 glutamate/aspartate ABC transporter, permease protein GltK YP_001871597.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2921 glutamate/aspartate ABC transporter, permease protein GltJ YP_001871598.1 PFAM: extracellular solute-binding protein family 3; KEGG: ypi:YpsIP31758_2920 glutamate/aspartate ABC transporter, periplasmic glutamate/aspartate-binding protein YP_001871599.1 Transfers the fatty acyl group on membrane lipoproteins YP_001871600.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: ypi:YpsIP31758_2918 magnesium and cobalt efflux protein CorC YP_001871601.1 PFAM: protein of unknown function UPF0054; KEGG: ypi:YpsIP31758_2917 conserved hypothetical protein TIGR00043 YP_001871602.1 PFAM: PhoH family protein; KEGG: yps:YPTB1112 hypothetical protein YP_001871603.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001871604.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_001871605.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001871606.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ypi:YpsIP31758_2912 hydrolase NagD YP_001871607.1 PFAM: ROK family protein; KEGG: ypi:YpsIP31758_2911 N-acetylglucosamine repressor YP_001871608.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_001871609.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_001871610.1 TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, N-acetylglucosamine-specific IIBC subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease EIIA 1 domain; phosphotransferase system PTS EIIB protein; phosphotransferase system EIIC; KEGG: yps:YPTB1120 pts system, N-acetylglucosamine-specific IIABC component YP_001871611.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001871612.1 PFAM: outer membrane porin; KEGG: yps:YPTB1122 possible outermembrane porin (OPR family) YP_001871613.1 PFAM: Carbohydrate-binding chitobiase/hexosaminidase-type domain protein; glycoside hydrolase family 20 domain protein; Beta-N-acetylhexosaminidase-like; Glycoside hydrolase, family 20, catalytic core; KEGG: ypi:YpsIP31758_2903 chitobiase YP_001871614.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001871615.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001871616.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: ypi:YpsIP31758_2899 transcriptional regulator, CopG family YP_001871619.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: yps:YPTB1128 hypothetical protein YP_001871620.1 KEGG: ypi:YpsIP31758_2897 hypothetical protein YP_001871621.1 KEGG: ypm:YP_1076 hypothetical protein YP_001871622.1 KEGG: ypn:YPN_1124 integrase YP_001871623.1 PFAM: transposase IS3/IS911 family protein; KEGG: ypi:YpsIP31758_2896 transposase YP_001871624.1 KEGG: ypi:YpsIP31758_2895 phage integrase family protein YP_001871625.1 KEGG: ent:Ent638_0478 hypothetical protein YP_001871626.1 PFAM: protein of unknown function DUF1219; KEGG: ent:Ent638_0477 protein of unknown function DUF1219 YP_001871627.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: yps:YPTB3876 transposase/IS protein YP_001871628.1 PFAM: Integrase catalytic region; Resolvase helix-turn-helix domain protein; KEGG: yps:YPTB3875 putative transposase YP_001871629.1 PFAM: YagBYeeUYfjZ family protein; KEGG: plu:plu0134 hypothetical protein YP_001871630.1 PFAM: DNA repair protein RadC; KEGG: ent:Ent638_0474 DNA repair protein RadC YP_001871631.1 PFAM: protein of unknown function DUF932; KEGG: ecj:JW0242 conserved hypothetical protein YP_001871632.1 KEGG: eca:ECA2857 hypothetical protein YP_001871633.1 KEGG: eca:ECA2856 hypothetical protein YP_001871634.1 PFAM: GTP-binding protein HSR1-related; KEGG: eca:ECA2860 hypothetical protein YP_001871635.1 KEGG: spe:Spro_1780 hypothetical protein YP_001871636.1 KEGG: spe:Spro_1781 hypothetical protein YP_001871637.1 KEGG: ecj:JW2603 hypothetical protein YP_001871638.1 PFAM: Prophage CP4-57 regulatory; KEGG: ecj:JW2604 DNA-binding transcriptional activator YP_001871640.1 KEGG: ecw:EcE24377A_3022 hypothetical protein YP_001871641.1 KEGG: lga:LGAS_1467 hypothetical protein YP_001871642.1 KEGG: spa:M6_Spy0486 chromosome segregation ATPase YP_001871643.1 CP4-57 prophage; integrase YP_001871644.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001871645.1 PFAM: cyclase/dehydrase; KEGG: yps:YPTB1136 hypothetical protein YP_001871646.1 PFAM: protein of unknown function UPF0125; KEGG: yps:YPTB1137 hypothetical protein YP_001871647.1 PFAM: SmpA/OmlA domain protein; KEGG: yps:YPTB1138 hypothetical protein YP_001871648.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: ypi:YpsIP31758_2889 DNA repair protein RecN YP_001871649.1 PFAM: ATP-NAD/AcoX kinase; KEGG: yps:YPTB1140 inorganic polyphosphate/ATP-NAD kinase YP_001871650.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001871651.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001871652.1 TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: yps:YPTB1143 succinate dehydrogenase cytochrome b556 large membrane subunit YP_001871653.1 TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: ypi:YpsIP31758_2884 succinate dehydrogenase, hydrophobic membrane anchor protein YP_001871654.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001871655.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001871656.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001871657.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001871658.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001871659.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001871660.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: ypi:YpsIP31758_2876 cytochrome d ubiquinol oxidase, subunit I YP_001871661.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: ypi:YpsIP31758_2875 cytochrome d ubiquinol oxidase, subunit II YP_001871662.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: ypi:YpsIP31758_2874 cyd operon protein YbgT YP_001871663.1 TIGRFAM: cyd operon protein YbgE; PFAM: Cyd operon protein YbgE; KEGG: ypp:YPDSF_2577 hypothetical protein YP_001871664.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_001871665.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001871666.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_001871667.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_001871668.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001871669.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: ypi:YpsIP31758_2867 peptidoglycan-associated lipoprotein YP_001871670.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_001871671.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001871672.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: ypi:YpsIP31758_2864 nicotinamide mononucleotide transporter PnuC YP_001871673.1 involved in zinc efflux across the cytoplasmic membrane YP_001871675.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001871676.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001871677.1 PFAM: PsiF repeat protein; KEGG: ypi:YpsIP31758_2859 phosphate starvation-inducible protein PsiF YP_001871678.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose YP_001871679.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_001871680.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_001871681.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: yps:YPTB1171 UDP-galactose-4-epimerase YP_001871682.1 PFAM: Abortive infection protein; KEGG: ypi:YpsIP31758_2854 CAAX amino terminal protease family protein YP_001871684.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_001871685.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_001871686.1 KEGG: ypi:YpsIP31758_2851 hypothetical protein YP_001871687.1 with ModCB is involved in the high-affinity transport of molybdate YP_001871688.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_001871689.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_001871690.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily YP_001871691.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_001871692.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_001871693.1 KEGG: yps:YPTB1182 biotin synthase; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001871694.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_001871695.1 TIGRFAM: biotin biosynthesis protein BioC; PFAM: protein of unknown function DUF691 methyltransferase-related; Methyltransferase type 11; Methyltransferase type 12; KEGG: yps:YPTB1184 biotin synthesis protein BioC YP_001871696.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001871697.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1186 putative ABC branched chain amino acid transporter, ATP binding subunit YP_001871698.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001871699.1 KEGG: yps:YPTB1188 hypothetical protein YP_001871700.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: ypi:YpsIP31758_2837 hypothetical protein YP_001871701.1 KEGG: ypg:YpAngola_A1433 hypothetical protein YP_001871702.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001871703.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001871704.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001871705.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_001871706.1 PFAM: protein of unknown function UPF0005; KEGG: ypi:YpsIP31758_2832 hypothetical protein YP_001871707.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001871708.1 catalyzes the formation of betaine from betaine aldehyde YP_001871709.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001871710.1 proton-motive-force-driven choline transporter YP_001871711.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB1199 DNA-binding transcriptional activator YP_001871712.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: yps:YPTB1200 possible drug/metabolite efflux pump (DMT superfamily) YP_001871713.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_001871714.1 TIGRFAM: nucleoside transporter; PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_2823 xanthosine transporter XapB YP_001871715.1 KEGG: ypn:YPN_2826 hypothetical protein YP_001871716.1 KEGG: ypm:YP_0984 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001871717.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: yps:YPTB1205 transcriptional regulatory protein HydG YP_001871718.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: ypi:YpsIP31758_2819 oxidoreductase, FAD/FMN-binding YP_001871719.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_2818 substrate-binding transcriptional regulator, LysR family YP_001871720.1 PFAM: Ethyl tert-butyl ether degradation EthD; KEGG: ypi:YpsIP31758_2816 hypothetical protein YP_001871721.1 PFAM: ABC-2 type transporter; KEGG: ypi:YpsIP31758_2815 ABC transporter, permease protein YP_001871722.1 PFAM: ABC-2 type transporter; KEGG: ypi:YpsIP31758_2814 ABC transporter, permease protein YP_001871723.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_2813 ABC transporter, ATP-binding protein YP_001871724.1 PFAM: secretion protein HlyD family protein; KEGG: yps:YPTB1212 hypothetical protein YP_001871725.1 PFAM: regulatory protein TetR; Transcriptional regulator TetR; KEGG: ypi:YpsIP31758_2811 transcriptional regulator, TetR family YP_001871726.1 this helicase is not essential cell growth YP_001871727.1 KEGG: ypn:YPN_2813 hypothetical protein YP_001871728.1 KEGG: ypn:YPN_2812 transposase YP_001871729.1 KEGG: ypm:YP_0971 hypothetical protein YP_001871730.1 KEGG: fgr:FG00347.1 hypothetical protein YP_001871732.1 KEGG: ypn:YPN_2809 hypothetical protein YP_001871733.1 KEGG: ypn:YPN_2813 hypothetical protein YP_001871734.1 KEGG: ypn:YPN_2807 transposase YP_001871735.1 PFAM: dihydrouridine synthase DuS; KEGG: yps:YPTB1216 tRNA-dihydrouridine synthase C YP_001871736.1 KEGG: ypi:YpsIP31758_2807 hypothetical protein YP_001871737.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_001871738.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_001871739.1 TIGRFAM: adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: ypi:YpsIP31758_2804 adenylate cyclase, class IV YP_001871740.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: ypi:YpsIP31758_2803 HNH endonuclease domain protein YP_001871741.1 KEGG: ypi:YpsIP31758_2801 hypothetical protein YP_001871742.1 PFAM: Transglycosylase-associated protein; KEGG: ypi:YpsIP31758_2800 hypothetical protein YP_001871743.1 KEGG: ypi:YpsIP31758_2799 phosphonate ABC transporter, ATP-binding protein; TIGRFAM: phosphonate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001871744.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; phosphonate ABC transporter, periplasmic phosphonate binding protein; KEGG: yps:YPTB1224 ABC periplasmic phosphonate binding protein, PhnD YP_001871745.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2797 phosphonate ABC transporter, permease protein YP_001871746.1 TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yps:YPTB1226 ABC transport permease subunit, PhnE YP_001871747.1 PFAM: protein of unknown function DUF1456; KEGG: yps:YPTB1227 hypothetical protein YP_001871748.1 TIGRFAM: urea ABC transporter, urea binding protein; KEGG: yps:YPTB1228 ABC type periplasmic branched chain aa binding protein YP_001871749.1 TIGRFAM: urea ABC transporter, permease protein UrtB; PFAM: inner-membrane translocator; KEGG: yps:YPTB1229 ABC type branched-chain amino acid transporter, permease protein YP_001871750.1 TIGRFAM: urea ABC transporter, permease protein UrtC; PFAM: inner-membrane translocator; KEGG: yps:YPTB1230 ABC type branched-chain amino acid transporter, permease protein YP_001871751.1 TIGRFAM: urea ABC transporter, ATP-binding protein UrtD; PFAM: ABC transporter related; KEGG: yps:YPTB1231 ABC branch chain aa transporter, ATP-binding subunit YP_001871752.1 KEGG: ypm:YP_0945 putative ABC transport ATP-binding subunit; TIGRFAM: urea ABC transporter, ATP-binding protein UrtE; PFAM: ABC transporter related; SMART: AAA ATPase YP_001871753.1 KEGG: yps:YPTB1233 hypothetical protein YP_001871754.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: yps:YPTB1234 putative pyridoxal-dependent decarboxylase YP_001871755.1 PFAM: Rhodanese domain protein; KEGG: yps:YPTB1235 putative sulfurtransferase YP_001871756.1 PFAM: Substrate-binding region of ABC-type glycine betaine transport system; KEGG: ypi:YpsIP31758_2786 quaternary amine uptake ABC transporter (QAT) family, substrate-binding protein YP_001871757.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yps:YPTB1237 ABC type choline/glycine/betaine transporter, permease subunit YP_001871758.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1238 ABC type choline/glycine/betaine transporter, ATP-binding subunit YP_001871759.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2783 quaternary amine uptake ABC transporter (QAT) family, permease protein YP_001871760.1 PFAM: amino acid permease-associated region; KEGG: ypi:YpsIP31758_2782 arginine/agmatine antiporter YP_001871761.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: ypi:YpsIP31758_2781 biodegradative arginine decarboxylase YP_001871762.1 KEGG: yps:YPTB1242 hypothetical protein YP_001871763.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypi:YpsIP31758_2779 integral membrane protein YP_001871764.1 PFAM: porin Gram-negative type; KEGG: yps:YPTB1244 general bacterial porin (GBP) family protein YP_001871765.1 helicase involved in DNA repair and perhaps also replication YP_001871766.1 PFAM: Catalase domain protein; KEGG: yps:YPTB1246 catalase YP_001871767.1 PFAM: YfaZ family protein; KEGG: ypi:YpsIP31758_2775 putative outer membrane protein YP_001871768.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: ypi:YpsIP31758_2774 tyrosine-specific transport protein YP_001871769.1 TIGRFAM: molybdenum cofactor synthesis domain protein; competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; KEGG: ypg:YpAngola_A1317 putative competence/damage-inducible protein CinA YP_001871770.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001871771.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_001871772.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001871773.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001871774.1 Involved in ubiquinone biosynthesis YP_001871775.1 negatively supercoils closed circular double-stranded DNA YP_001871776.1 KEGG: ypi:YpsIP31758_2766 hypothetical protein YP_001871777.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase; KEGG: yps:YPTB1257 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_001871778.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_001871779.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: yps:YPTB1259 phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_001871780.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_2762 transporter, major facilitator family YP_001871782.1 allows for ions and hydrophilic solutes to cross the outer membrane YP_001871783.1 this protein has no known enzymatic function YP_001871784.1 KEGG: ypi:YpsIP31758_2756 putative transport protein YP_001871785.1 PFAM: beta-lactamase domain protein; KEGG: ypi:YpsIP31758_2754 metallo-beta-lactamase family protein YP_001871786.1 PFAM: histidine kinase HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: yps:YPTB1265 putative methyl-accepting chemotaxis protein YP_001871787.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA YP_001871788.1 PFAM: DinI family protein; KEGG: ypi:YpsIP31758_2751 DinI family protein YP_001871789.1 PFAM: helix-turn-helix domain protein; peptidase S24 and S26 domain protein; KEGG: ypi:YpsIP31758_2750 phage repressor protein YP_001871791.1 PFAM: antitermination Q family protein; KEGG: ypi:YpsIP31758_2749 phage antitermination protein Q YP_001871792.1 PFAM: type III effector Hrp-dependent outers; KEGG: yps:YPTB1270 hypothetical protein YP_001871793.1 PFAM: class II aldolase/adducin family protein; KEGG: ypp:YPDSF_2459 class II aldolase-family protein YP_001871794.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: yps:YPTB1272 putative transcriptional regulatory protein YP_001871795.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: ypi:YpsIP31758_2745 AP endonuclease, family 2 YP_001871796.1 KEGG: yps:YPTB1274 putative bacteriophage protein YP_001871797.1 KEGG: ypi:YpsIP31758_2743 hypothetical protein YP_001871798.1 KEGG: yps:YPTB1276 putative bacteriophage protein YP_001871799.1 PFAM: Mu tail sheath family protein; KEGG: yps:YPTB1277 putative bacteriophage tail sheath protein YP_001871800.1 KEGG: ypi:YpsIP31758_2740 hypothetical protein YP_001871801.1 KEGG: yps:YPTB1279 putative bacteriophage protein YP_001871802.1 KEGG: yps:YPTB1280 putative bacteriophage coat protein YP_001871803.1 PFAM: DNA circulation family protein; KEGG: ypp:YPDSF_2448 bacteriophage protein YP_001871804.1 PFAM: Mu P family protein; KEGG: ypg:YpAngola_A1470 bacteriophage Mu P protein YP_001871805.1 TIGRFAM: phage baseplate assembly protein V; PFAM: Mu Gp45 domain protein; KEGG: ypi:YpsIP31758_2735 phage baseplate assembly protein YP_001871806.1 PFAM: GP46 family protein; KEGG: yps:YPTB1284 putative bacteriophage protein GP46 YP_001871807.1 PFAM: Baseplate J family protein; KEGG: ypi:YpsIP31758_2733 baseplate J-like protein YP_001871808.1 KEGG: yps:YPTB1286 putative bacteriophage protein GP48 YP_001871809.1 PFAM: Tail Collar domain protein; KEGG: ypi:YpsIP31758_2731 tail collar domain protein YP_001871810.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: yps:YPTB1289 putative LacI-family regulatory protein YP_001871812.1 PFAM: glycoside hydrolase family 1; KEGG: yps:YPTB1290 6-phospho-beta-glucosidase YP_001871813.1 KEGG: yps:YPTB1291 hypothetical protein YP_001871814.1 KEGG: ypp:YPDSF_2438 hypothetical protein YP_001871815.1 PFAM: Colicin D; KEGG: yps:YPTB1292 hypothetical protein YP_001871816.1 KEGG: yps:YPTB1293 hypothetical protein YP_001871817.1 KEGG: ypi:YpsIP31758_0047 hypothetical protein YP_001871818.1 KEGG: ypk:y2927 hypothetical protein YP_001871819.1 PFAM: sulfatase; KEGG: ypi:YpsIP31758_2723 sulfatase family protein YP_001871820.1 PFAM: protein of unknown function DUF1414; KEGG: yen:YE1420 hypothetical protein YP_001871821.1 PFAM: 37kDa nucleoid-associated protein; KEGG: yps:YPTB1298 nucleoid-associated protein NdpA YP_001871822.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001871823.1 PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: yps:YPTB1300 putative DEAD box helicase family protein YP_001871824.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_001871825.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_001871826.1 KEGG: ypi:YpsIP31758_2715 hypothetical protein YP_001871827.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1304 ABC oligo-dipeptide/nickel transporter, fused ATP-binding domains YP_001871828.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2713 ABC transporter, permease protein YP_001871829.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2712 ABC transporter, permease protein YP_001871830.1 PFAM: extracellular solute-binding protein family 5; KEGG: yps:YPTB1307 putative ABC transporter, oligo-dipeptide/nickel binding protein YP_001871831.1 PFAM: EAL domain protein; KEGG: ypi:YpsIP31758_2710 protein rtn YP_001871832.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_001871833.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: yps:YPTB1310 hypothetical protein YP_001871834.1 PFAM: cobalamin synthesis protein P47K; KEGG: ypi:YpsIP31758_2705 CobW/P47K family protein YP_001871835.1 KEGG: yps:YPTB1312 hypothetical protein YP_001871836.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: ypi:YpsIP31758_2703 uxu operon transcriptional regulator YP_001871837.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: ypi:YpsIP31758_2702 mannitol dehydrogenase family protein YP_001871838.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_001871839.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_001871840.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: yps:YPTB1317 putative HAAAP family tryptophan-specific transporter mtr YP_001871841.1 PFAM: protein of unknown function UPF0153; KEGG: yps:YPTB1318 hypothetical protein YP_001871842.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: yps:YPTB1319 putative short chain oxidoreductase YP_001871843.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: yps:YPTB1320 putative D-isomer specific 2-hydroxyacid dehydrogenase family YP_001871844.1 KEGG: yps:YPTB1321 hypothetical protein YP_001871846.1 PFAM: Aldehyde Dehydrogenase_; KEGG: ypi:YpsIP31758_2692 putative succinate-semialdehyde dehydrogenase (NADP+) YP_001871847.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: yps:YPTB1323 putative carbohydrate kinase YP_001871848.1 KEGG: yps:YPTB1325 ABC transporter, periplasmic sugar-binding protein YP_001871850.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1326 ABC sugar transporter, fused ATP-binding subunits YP_001871851.1 PFAM: inner-membrane translocator; KEGG: yps:YPTB1327 ABC sugar transporter, permease subunit YP_001871852.1 PFAM: NUDIX hydrolase; KEGG: yps:YPTB1328 putative Mut family protein YP_001871853.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_001871854.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_001871855.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001871856.1 PFAM: transcriptional regulator domain protein; KEGG: ypi:YpsIP31758_2680 transcriptional regulator YP_001871857.1 KEGG: ypi:YpsIP31758_2679 hypothetical protein YP_001871858.1 KEGG: yps:YPTB1334 pH 6 antigen precursor (antigen 4) (adhesin) YP_001871859.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: ypi:YpsIP31758_2677 gram-negative pili assembly chaperone YP_001871860.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: ypi:YpsIP31758_2676 fimbrial usher protein YP_001871861.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_001871862.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_2674 hypothetical protein YP_001871863.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_2672 substrate-binding transcriptional regulator, LysR family YP_001871864.1 KEGG: ypi:YpsIP31758_2671 hypothetical protein YP_001871865.1 PFAM: amino acid permease-associated region; KEGG: ypi:YpsIP31758_2670 lysine-specific permease LysP YP_001871866.1 PFAM: periplasmic binding protein; KEGG: ypi:YpsIP31758_2669 putative ABC transporter, periplasmic iron siderophore/cobalamin-binding protein YP_001871867.1 PFAM: transport system permease protein; KEGG: ypi:YpsIP31758_2668 ABC transporter, iron chelate uptake transporter (FeCT) family, permease protein YP_001871868.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_2667 ABC transporter, iron chelate uptake transporter (FeCT) family, ATP-binding protein YP_001871869.1 YiuR; outer membrane siderophore receptor YP_001871870.1 PFAM: Glutathione S-transferase domain; KEGG: ypg:YpAngola_A1542 putative glutathione S-transferase YP_001871871.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; KEGG: ypi:YpsIP31758_2664 HAD-superfamily hydrolase, subfamily IB, TIGR01490 YP_001871872.1 KEGG: ypg:YpAngola_A1544 hypothetical protein YP_001871873.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: ypi:YpsIP31758_2663 oxidoreductase, 2OG-Fe(II) oxygenase family YP_001871874.1 PFAM: NLPA lipoprotein; KEGG: ypi:YpsIP31758_2662 lipoprotein, NlpA family YP_001871875.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_2661 ABC transporter, ATP-binding protein YP_001871876.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2660 ABC transporter, permease protein YP_001871877.1 PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: yps:YPTB1351 D-alanyl-D-alanine carboxypeptidase YP_001871878.1 TIGRFAM: serine transporter; PFAM: Amino acid transporter transmembrane; KEGG: ypi:YpsIP31758_2656 serine transporter YP_001871879.1 PFAM: regulatory protein DeoR; KEGG: ypi:YpsIP31758_2653 transcriptional regulator, DeoR family YP_001871880.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001871881.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: ypi:YpsIP31758_2651 PAP2 family protein YP_001871882.1 KEGG: yps:YPTB1356 hypothetical protein YP_001871883.1 TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: ypi:YpsIP31758_2649 putative transport protein YP_001871884.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001871885.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_001871886.1 KEGG: ypi:YpsIP31758_2646 hypothetical protein YP_001871887.1 PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_2645 putrescine ABC transporter, periplasmic putrescine binding protein YP_001871888.1 part of the PotFGHI ATP-dependent putrescine transporter YP_001871889.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2643 putrescine ABC transporter, permease protein YP_001871890.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypg:YpAngola_A1566 putrescine ABC transporter, permease protein YP_001871891.1 KEGG: ypi:YpsIP31758_2641 hypothetical protein YP_001871892.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_001871893.1 KEGG: yps:YPTB1367 ABC transporter, periplasmic arginine binding protein ArtJ; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor YP_001871894.1 KEGG: ypi:YpsIP31758_2638 hypothetical protein YP_001871895.1 KEGG: ypg:YpAngola_A1571 hypothetical protein YP_001871896.1 PFAM: band 7 protein; KEGG: ypi:YpsIP31758_2636 SPFH/band 7 family protein YP_001871897.1 PFAM: periplasmic binding protein; KEGG: yps:YPTB1369 putative periplasmic iron/siderophore binding protein YP_001871898.1 PFAM: transport system permease protein; KEGG: yps:YPTB1370 putative FecCD ABC type transporter, permease protein YP_001871899.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1371 putative iron ABC type transport, ATP-binding protein YP_001871900.1 KEGG: ypi:YpsIP31758_2632 hypothetical protein YP_001871901.1 KEGG: yps:YPTB1373 hypothetical protein YP_001871902.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypi:YpsIP31758_2630 integral membrane protein YP_001871903.1 with ArtPQJI acts to transport arginine across the inner membrane YP_001871904.1 with ArtPMJI transports arginine across the inner membrane YP_001871905.1 KEGG: ypi:YpsIP31758_2626 arginine ABC transporter, periplasmic substrate-binding protein ArtI; TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor YP_001871906.1 With ArtMQJI transports arginine across the inner membrane YP_001871907.1 catalyzes the interconversion of chorismate to prephenate YP_001871908.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_001871909.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ypi:YpsIP31758_2622 NAD-dependent epimerase/dehydratase family protein YP_001871910.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: ypi:YpsIP31758_2621 NAD dependent epimerase/dehydratase family protein YP_001871911.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine YP_001871912.1 catalyzes the formation of acetate from pyruvate YP_001871913.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: yps:YPTB1385 HCP oxidoreductase, NADH-dependent YP_001871914.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001871915.1 PFAM: protein of unknown function DUF340 membrane; KEGG: ypi:YpsIP31758_2616 hypothetical protein YP_001871916.1 KEGG: ypi:YpsIP31758_2614 hypothetical protein YP_001871918.1 PFAM: protein of unknown function DUF535; KEGG: yps:YPTB1389 putative virulence factor YP_001871919.1 confers macrolide resistance via active drug efflux YP_001871920.1 with MacA is involved in the export of macrolide YP_001871921.1 KEGG: ypi:YpsIP31758_2609 cold shock domain protein CspD; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein YP_001871922.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001871923.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_001871924.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001871925.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001871926.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001871927.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001871928.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ypi:YpsIP31758_2598 thioredoxin-disulfide reductase YP_001871929.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001871930.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: ypi:YpsIP31758_2596 DNA translocase FtsK YP_001871931.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_001871932.1 PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_2594 replication/recombination-associated protein RarA YP_001871934.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001871935.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_2592 transporter, major facilitator family YP_001871936.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_001871937.1 PFAM: glycosyl transferase family 25; KEGG: ypi:YpsIP31758_2590 LPS glycosyltransferase family protein YP_001871938.1 TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase PFL; KEGG: ypi:YpsIP31758_2589 formate acetyltransferase YP_001871939.1 PFAM: formate/nitrite transporter; KEGG: ypi:YpsIP31758_2588 putative formate transporter FocA YP_001871940.1 PFAM: protein of unknown function DUF181; KEGG: ypi:YpsIP31758_2587 hypothetical protein YP_001871941.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis YP_001871942.1 PFAM: Haemagluttinin domain protein; KEGG: ypi:YpsIP31758_2585 putative haemagglutinin/invasin YP_001871943.1 KEGG: yps:YPTB1413 hypothetical protein YP_001871944.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001871945.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001871946.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001871947.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001871948.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001871950.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: yps:YPTB1419 hypothetical protein YP_001871951.1 involved in the transport of lipid A across the inner membrane YP_001871952.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001871953.1 PFAM: protein of unknown function DUF1338; KEGG: yps:YPTB1422 hypothetical protein YP_001871954.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ypi:YpsIP31758_2574 cold shock DNA-binding domain protein YP_001871955.1 PFAM: protein of unknown function DUF343; KEGG: ypi:YpsIP31758_2572 hypothetical protein YP_001871956.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001871957.1 KEGG: yps:YPTB1426 hypothetical protein YP_001871958.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_001871959.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_001871960.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_001871961.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_001871962.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: yps:YPTB1431 hypothetical protein YP_001871963.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: ypi:YpsIP31758_2562 hypothetical protein YP_001871964.1 PFAM: beta-lactamase domain protein; KEGG: ypi:YpsIP31758_2561 metallo-beta-lactamase family protein YP_001871965.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001871966.1 PFAM: porin Gram-negative type; KEGG: yps:YPTB1435 general bacterial porin (GBP) family protein YP_001871967.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001871968.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001871970.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: yps:YPTB1438 putative aminopeptidase N YP_001871971.1 PFAM: transposase mutator type; KEGG: yps:YPTB3311 putative transposase YP_001871972.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001871973.1 PFAM: protein of unknown function DUF1379; KEGG: ypi:YpsIP31758_2554 hypothetical protein YP_001871974.1 PFAM: ferredoxin; MOSC domain containing protein; MOSC domain protein beta barrel domain protein; KEGG: ypi:YpsIP31758_2553 MOSC/iron-sulfur cluster binding domain protein YP_001871975.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001871976.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001871977.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: ypg:YpAngola_A1989 paraquat-inducible protein A YP_001871978.1 PFAM: Mammalian cell entry related domain protein; KEGG: ypp:YPDSF_2274 paraquat-inducible protein B YP_001871979.1 PFAM: protein of unknown function DUF330; KEGG: ypg:YpAngola_A1991 putative lipoprotein YP_001871980.1 PFAM: ribosome modulation factor; KEGG: yps:YPTB1448 putative ribosome modulation factor YP_001871981.1 KEGG: ypp:YPDSF_2525 hypothetical protein YP_001871982.1 PFAM: transposase IS200-family protein; KEGG: ypi:YpsIP31758_3905 IS1541, transposase YP_001871983.1 FabF, beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP. YP_001871984.1 KEGG: ypg:YpAngola_A1941 hypothetical protein YP_001871985.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001871986.1 KEGG: ypi:YpsIP31758_2545 hypothetical protein YP_001871987.1 PFAM: protein of unknown function DUF1047; KEGG: ypi:YpsIP31758_2544 hypothetical protein YP_001871988.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_001871989.1 PFAM: cell division inhibitor SulA; KEGG: ypg:YpAngola_A3200 cell division inhibitor SulA YP_001871990.1 PFAM: TfoX domain protein; KEGG: ypi:YpsIP31758_2539 DNA transformation protein TfoX YP_001871991.1 TIGRFAM: hypothetical membrane protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: ypi:YpsIP31758_2538 inner membrane protein YccS YP_001871992.1 PFAM: protein of unknown function DUF307; KEGG: yps:YPTB1457 hypothetical protein YP_001871993.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_001871994.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001871995.1 KEGG: ypp:YPDSF_1532 hypothetical protein YP_001871996.1 PFAM: CoA-binding domain protein; KEGG: ypp:YPDSF_1531 hypothetical protein YP_001871997.1 TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: ypp:YPDSF_1530 hypothetical protein YP_001871998.1 SMART: PUA domain containing protein; KEGG: ypp:YPDSF_1529 hypothetical protein YP_001871999.1 catalyzes the hydrolysis of acylphosphate YP_001872000.1 TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC family protein; KEGG: ypp:YPDSF_1527 sulfite reductase subunit protein YP_001872001.1 KEGG: ypp:YPDSF_1526 transposase YP_001872002.1 PFAM: FAD linked oxidase domain protein; KEGG: yps:YPTB1469 putative oxidoreductase YP_001872003.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypp:YPDSF_1522 short chain dehydrogenase YP_001872004.1 KEGG: ypi:YpsIP31758_2522 hypothetical protein YP_001872005.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; KEGG: ypi:YpsIP31758_2521 thioester dehydratase family protein YP_001872006.1 PFAM: Beta-ketoacyl synthase; KEGG: yps:YPTB1473 putative beta-ketoacyl-[acyl-carrier-protein] synthase YP_001872007.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypi:YpsIP31758_2519 short-chain dehydrogenase/reductase family protein YP_001872008.1 PFAM: Hydroxymethylglutaryl-coenzyme A synthase domain; Hydroxymethylglutaryl-coenzyme A synthase domain protein; KEGG: ypi:YpsIP31758_2518 putative hydroxymethylglutaryl-coenzyme A synthase YP_001872009.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ypp:YPDSF_1516 enoyl-CoA hydratase YP_001872010.1 involved in polyketide production YP_001872011.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: yps:YPTB1478 putative 3-oxoacyl-acyl carrier protein reductase YP_001872012.1 KEGG: ypi:YpsIP31758_2514 hypothetical protein YP_001872013.1 KEGG: ypi:YpsIP31758_2513 putative acyl carrier protein YP_001872014.1 KEGG: ypi:YpsIP31758_2512 putative acyltransferase YP_001872015.1 KEGG: ype:YPO1464 hypothetical protein YP_001872016.1 TIGRFAM: type VI secretion protein, VC_A0107 family; PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_2511 hypothetical protein YP_001872017.1 TIGRFAM: type VI secretion protein, EvpB/VC_A0108 family; PFAM: protein of unknown function DUF877; KEGG: yps:YPTB1484 hypothetical protein YP_001872018.1 TIGRFAM: type VI secretion protein, VC_A0114 family; PFAM: protein of unknown function DUF876; KEGG: yps:YPTB3250 hypothetical protein YP_001872019.1 KEGG: yps:YPTB1486 hypothetical protein YP_001872020.1 PFAM: OmpA/MotB domain protein; KEGG: yps:YPTB1487 OmpA family of outer membrane porins YP_001872021.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: ypi:YpsIP31758_2506 hypothetical protein YP_001872022.1 KEGG: yps:YPTB1489 Clp ATPase; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001872023.1 TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: yps:YPTB1490 hypothetical protein YP_001872024.1 KEGG: yps:YPTB1491 hypothetical protein YP_001872025.1 KEGG: ypi:YpsIP31758_0787 putative lipoprotein YP_001872026.1 TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: yps:YPTB1493 hypothetical protein YP_001872027.1 KEGG: ypi:YpsIP31758_0789 hypothetical protein YP_001872028.1 PFAM: Peptidoglycan-binding LysM; KEGG: yps:YPTB1495 possible LysM domain YP_001872029.1 KEGG: yps:YPTB1496 hypothetical protein YP_001872030.1 KEGG: ypi:YpsIP31758_0793 hypothetical protein YP_001872031.1 KEGG: ypi:YpsIP31758_2496 hypothetical protein YP_001872032.1 PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: yps:YPTB1498 hypothetical protein YP_001872033.1 TIGRFAM: type VI secretion-associated protein, VC_A0119 family; PFAM: ImpA domain protein; KEGG: yps:YPTB1499 hypothetical protein YP_001872034.1 KEGG: yps:YPTB1500 hypothetical protein YP_001872035.1 KEGG: yps:YPTB1501 hypothetical protein YP_001872036.1 TIGRFAM: type VI secretion protein, VC_A0110 family; PFAM: protein of unknown function DUF879; KEGG: yps:YPTB1502 hypothetical protein YP_001872037.1 TIGRFAM: type VI secretion protein, VC_A0111 family; PFAM: protein of unknown function DUF1305; KEGG: yps:YPTB1503 hypothetical protein YP_001872038.1 KEGG: ypi:YpsIP31758_2487 hypothetical protein YP_001872039.1 TIGRFAM: type VI secretion system lysozyme-related protein; PFAM: GPW/gp25 family protein; KEGG: yps:YPTB1505 hypothetical protein YP_001872040.1 PFAM: ImpA domain protein; KEGG: ypi:YpsIP31758_2485 ImpA domain protein YP_001872041.1 KEGG: ypp:YPDSF_1485 hypothetical protein YP_001872042.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1508 ABC transporter ATP-binding protein YP_001872043.1 KEGG: yps:YPTB1509 hypothetical protein YP_001872044.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001872045.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_001872047.1 PFAM: Radical SAM domain protein; KEGG: ypi:YpsIP31758_2479 radical SAM domain protein YP_001872048.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1513 ABC transporter ATP-binding protein YP_001872049.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: yps:YPTB1514 hypothetical protein YP_001872050.1 KEGG: yps:YPTB1515 hypothetical protein YP_001872051.1 KEGG: ypg:YpAngola_A3008 hypothetical protein YP_001872052.1 TIGRFAM: S-formylglutathione hydrolase; PFAM: putative esterase; KEGG: yps:YPTB1516 putative esterase YP_001872053.1 TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ypp:YPDSF_1475 alcohol dehydrogenase YP_001872054.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypp:YPDSF_1474 LysR-family transcriptional regulatory protein YP_001872055.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_1473 hypothetical protein YP_001872056.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001872057.1 PFAM: protein of unknown function DUF405; protein of unknown function DUF418; KEGG: yps:YPTB1521 hypothetical protein YP_001872058.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_2467 galactose ABC transporter, periplasmic galactose-binding protein YP_001872059.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_001872060.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_001872061.1 PFAM: protein of unknown function DUF218; KEGG: ypi:YpsIP31758_2464 putative SanA protein YP_001872062.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001872063.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001872064.1 PFAM: LrgB family protein; KEGG: ypi:YpsIP31758_2461 LrgB family protein YP_001872065.1 PFAM: LrgA family protein; KEGG: ypi:YpsIP31758_2460 LrgA family protein YP_001872066.1 PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB1530 putative MFS multidrug efflux pump YP_001872067.1 KEGG: ypi:YpsIP31758_2458 hypothetical protein YP_001872068.1 KEGG: ypi:YpsIP31758_2457 hypothetical protein YP_001872069.1 KEGG: ypi:YpsIP31758_2456 hypothetical protein YP_001872070.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001872071.1 KEGG: ypp:YPDSF_1453 hypothetical protein YP_001872072.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001872073.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001872074.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_001872075.1 PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: ypi:YpsIP31758_2450 membrane protein TerC family/CBS domain protein YP_001872076.1 PFAM: ferric iron reductase; KEGG: yps:YPTB1540 ferric iron reductase involved in ferric hydroximate transport YP_001872077.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: yps:YPTB1541 putative decarboxylase YP_001872078.1 KEGG: ypi:YpsIP31758_2447 lysine N6-hydroxylase/L-ornithine N5-oxygenase family YP_001872079.1 KEGG: ypp:YPDSF_1445 siderophore biosynthetic enzyme YP_001872080.1 PFAM: IucA/IucC family protein; KEGG: yps:YPTB1544 putative siderophore biosynthetic enzyme YP_001872081.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypp:YPDSF_1443 iron-siderophore transport system, ATP-binding component YP_001872082.1 PFAM: transport system permease protein; KEGG: ypp:YPDSF_1442 iron-siderophore transport system, membrane permease component YP_001872083.1 PFAM: transport system permease protein; KEGG: yps:YPTB1547 putative ABC iron-siderophore transporter, permease subunit YP_001872084.1 PFAM: periplasmic binding protein; KEGG: ypi:YpsIP31758_2441 ferric enterobactin ABC transporter, ferric enterobactin-binding periplasmic protein FepB YP_001872085.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: yps:YPTB1549 putative OMR family iron-siderophore receptor YP_001872086.1 PFAM: IucA/IucC family protein; KEGG: yps:YPTB1550 putative siderophore biosynthetic enzyme YP_001872087.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: ypi:YpsIP31758_2438 UTP-glucose-1-phosphate uridylyltransferase YP_001872088.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: ypn:YPN_2440 UTP-glucose-1-phosphate uridylyltransferase YP_001872089.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001872090.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001872091.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001872092.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001872093.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001872094.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001872095.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001872096.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001872097.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001872098.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: ypp:YPDSF_1426 hypothetical protein YP_001872099.1 KEGG: yps:YPTB1564 hypothetical protein YP_001872100.1 KEGG: ypi:YpsIP31758_2425 hypothetical protein YP_001872102.1 PFAM: inner-membrane translocator; KEGG: yps:YPTB1565 ABC sugar transporter, permease subunit YP_001872103.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1566 putative ABC sugar transporter, fused ATP binding domains YP_001872104.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_001872105.1 KEGG: yen:YE2760 hypothetical protein YP_001872106.1 PFAM: amino acid permease-associated region; KEGG: ypi:YpsIP31758_2421 amino acid permease family protein YP_001872107.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001872108.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: yps:YPTB1570 hypothetical protein YP_001872109.1 PFAM: protein of unknown function DUF496; KEGG: ypi:YpsIP31758_2417 hypothetical protein YP_001872110.1 PFAM: Ig domain protein group 1 domain protein; KEGG: yps:YPTB1572 putative invasin YP_001872111.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_1412 transmembrane transporter YP_001872112.1 PFAM: putative thiol-disulphide oxidoreductase DCC; KEGG: yps:YPTB1574 hypothetical protein YP_001872114.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypp:YPDSF_1410 oxidoreductase YP_001872115.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: yps:YPTB1576 2-hydroxyhepta-2,4-diene-1,7-dioateisomerase / 5-carboxymeth... YP_001872116.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: ypp:YPDSF_1408 racemase YP_001872117.1 KEGG: ypm:YP_1456 hypothetical protein YP_001872118.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_001872119.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_001872120.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: ypp:YPDSF_1405 sugar transporter YP_001872121.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_1404 sugar transporter YP_001872122.1 PFAM: polysaccharide deacetylase; KEGG: ypi:YpsIP31758_2405 polysaccharide deacetylase family protein YP_001872123.1 KEGG: ypp:YPDSF_1402 hypothetical protein YP_001872124.1 KEGG: ypi:YpsIP31758_2403 hypothetical protein YP_001872125.1 KEGG: ypp:YPDSF_1228 hypothetical protein YP_001872126.1 PFAM: Integrase catalytic region; Resolvase helix-turn-helix domain protein; KEGG: ypp:YPDSF_2253 transposase for insertion sequence IS100 YP_001872127.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: yps:YPTB3876 transposase/IS protein YP_001872128.1 KEGG: ypg:YpAngola_A2090 hypothetical protein YP_001872129.1 TIGRFAM: phage/conjugal plasmid C-4 type zinc finger protein, TraR family; PFAM: zinc finger DksA/TraR C4-type; KEGG: yps:YPTB1587 hypothetical protein YP_001872130.1 KEGG: cko:CKO_00902 hypothetical protein YP_001872131.1 KEGG: yps:YPTB1589 hypothetical protein YP_001872132.1 PFAM: Prophage CP4-57 regulatory; KEGG: cko:CKO_00903 hypothetical protein YP_001872133.1 KEGG: yps:YPTB1590 hypothetical protein YP_001872134.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: yps:YPTB1591 OMR family pesticin/yersiniabactin receptor protein YP_001872135.1 PFAM: AMP-dependent synthetase and ligase; KEGG: yps:YPTB1592 yersiniabactin siderophore biosynthetic protein YP_001872136.1 PFAM: Thioesterase; KEGG: ypg:YpAngola_A2095 yersiniabactin biosynthesis thioesterase YbtT YP_001872137.1 TIGRFAM: thiazolinyl imide reductase; PFAM: oxidoreductase domain protein; KEGG: ypp:YPDSF_1216 yersiniabactin biosynthetic protein YbtU YP_001872138.1 PFAM: Thioesterase; condensation domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Methyltransferase type 11; Methyltransferase type 12; Non-ribosomal peptide synthetase; KR domain protein; Beta-ketoacyl synthase ; Acyl transferase; KEGG: yps:YPTB1595 yersiniabactin biosynthetic protein YP_001872139.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Methyltransferase type 11; Methyltransferase type 12; Non-ribosomal peptide synthetase; KEGG: ypp:YPDSF_1214 yersiniabactin biosynthetic protein YP_001872140.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ypp:YPDSF_1213 transcriptional regulator YbtA YP_001872141.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1598 lipoprotein inner membrane ABC-transporter YP_001872142.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypp:YPDSF_1211 inner membrane ABC-transporter YbtQ YP_001872143.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_1210 signal transducer YP_001872144.1 catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin YP_001872145.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: ypp:YPDSF_1400 GerR-family transcriptional regulatory protein YP_001872146.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: ypp:YPDSF_1399 C4-dicarboxylate transporter, large subunit YP_001872147.1 PFAM: Tripartite ATP-independent periplasmic transporter DctQ component; KEGG: ypp:YPDSF_1398 C4-dicarboxylate transporter, small subunit YP_001872148.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: yps:YPTB1606 TRAP-T family C4-dicarboxylate transporter, periplasmic binding protein (DctP subunit) YP_001872149.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: yps:YPTB1607 putative phosphopantetheinyl transferase YP_001872151.1 PFAM: glycoside hydrolase clan GH-D; KEGG: yps:YPTB1608 alpha-galactosidase YP_001872152.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_001872153.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypp:YPDSF_1392 hypothetical protein YP_001872154.1 PFAM: protein of unknown function DUF980; KEGG: ypp:YPDSF_1391 hypothetical protein YP_001872155.1 PFAM: YCII-related; KEGG: ypi:YpsIP31758_2391 YciI domain protein YP_001872156.1 PFAM: protein of unknown function RIO1; KEGG: ypi:YpsIP31758_2390 RIO1 family protein kinase YP_001872157.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1614 putative ABC efflux transporter, fused ATP-binding and permease domains YP_001872158.1 KEGG: ypm:YP_1476 hypothetical protein YP_001872159.1 KEGG: ypi:YpsIP31758_2388 hypothetical protein YP_001872160.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ypi:YpsIP31758_2387 transcriptional regulator, AraC family YP_001872161.1 KEGG: ypg:YpAngola_A1671 hypothetical protein YP_001872162.1 KEGG: ypi:YpsIP31758_2386 hypothetical protein YP_001872163.1 KEGG: ypi:YpsIP31758_2385 hypothetical protein YP_001872164.1 KEGG: yps:YPTB1618 hypothetical protein YP_001872165.1 KEGG: ypi:YpsIP31758_2383 hypothetical protein YP_001872166.1 KEGG: ypi:YpsIP31758_2382 hypothetical protein YP_001872167.1 PFAM: amino acid permease-associated region; KEGG: ypp:YPDSF_1379 aromatic amino acid transport protein YP_001872168.1 catalyzes the transfer of palmitate to lipid A YP_001872169.1 KEGG: ypi:YpsIP31758_2379 hypothetical protein YP_001872170.1 KEGG: ypn:YPN_2377 hypothetical protein YP_001872171.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ypp:YPDSF_1377 cold shock protein YP_001872172.1 PFAM: protein of unknown function DUF152; KEGG: ypp:YPDSF_1376 hypothetical protein YP_001872173.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_001872174.1 KEGG: ypi:YpsIP31758_2375 hypothetical protein YP_001872175.1 KEGG: yps:YPTB1628 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001872176.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ypi:YpsIP31758_2373 ferrichrome receptor FcuA YP_001872177.1 PFAM: protein of unknown function DUF204; KEGG: ypp:YPDSF_1370 membrane protein YP_001872178.1 PFAM: protein of unknown function DUF986; KEGG: ypi:YpsIP31758_2371 hypothetical protein YP_001872179.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_001872180.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: ypp:YPDSF_1367 PTS system, mannose-specific IIC component YP_001872181.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PTS system, mannose/fructose/sorbose family, IIA subunit; PFAM: PTS system fructose subfamily IIA component; PTS system sorbose subfamily IIB component; KEGG: yps:YPTB1634 PTS system, mannose-specific IIAB component YP_001872183.1 PFAM: CBS domain containing protein; transporter-associated region; Integral membrane protein TerC; KEGG: ypm:YP_1633 hypothetical protein YP_001872184.1 TIGRFAM: homoprotocatechuate degradation operon regulator, HpaR; PFAM: regulatory protein MarR; KEGG: ypi:YpsIP31758_2366 homoprotocatechuate degradation operon regulator, HpaR YP_001872185.1 TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, HpaG1 subunit; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: ypi:YpsIP31758_2365 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit YP_001872186.1 TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase,HpaG2 subunit; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: yps:YPTB1638 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase / 5-carboxymeth... YP_001872187.1 TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: yps:YPTB1639 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase YP_001872188.1 TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ypi:YpsIP31758_2362 3,4-dihydroxyphenylacetate 2,3-dioxygenase YP_001872189.1 PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: ypi:YpsIP31758_2361 5-carboxymethyl-2-hydroxymuconate delta isomerase YP_001872190.1 TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: Hydratase/decarboxylase; KEGG: ypi:YpsIP31758_2360 2-oxo-hepta-3-ene-1,7-dioic acid hydratase YP_001872191.1 TIGRFAM: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PFAM: HpcH/HpaI aldolase; KEGG: ypp:YPDSF_1356 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_001872192.1 TIGRFAM: 4-hydroxyphenylacetate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: ypn:YPN_2355 4-hydroxyphenylacetate permease YP_001872193.1 TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: yps:YPTB1645 4-hydroxyphenylacetate 3-monooxygenase YP_001872194.1 TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, reductase subunit; PFAM: flavin reductase domain protein FMN-binding; KEGG: ypi:YpsIP31758_2356 4-hydroxyphenylacetate 3-monooxygenase, reductase component YP_001872195.1 TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; KEGG: ypi:YpsIP31758_2355 L-serine ammonia-lyase YP_001872196.1 PFAM: NUDIX hydrolase; KEGG: ypi:YpsIP31758_2354 hydrolase, NUDIX family YP_001872197.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like; KEGG: yps:YPTB1649 para-aminobenzoate synthase component I YP_001872198.1 PFAM: protein of unknown function UPF0181; KEGG: yps:YPTB1650 hypothetical protein YP_001872199.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001872200.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001872201.1 PFAM: YebG family protein; KEGG: yps:YPTB1653 hypothetical protein YP_001872202.1 PFAM: protein of unknown function DUF437; KEGG: ypi:YpsIP31758_2348 hypothetical protein YP_001872203.1 secreted protein; unknown function YP_001872204.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: ypp:YPDSF_1343 oligopeptidase B YP_001872205.1 KEGG: ypi:YpsIP31758_2345 hypothetical protein YP_001872206.1 TIGRFAM: proline iminopeptidase; PFAM: alpha/beta hydrolase fold; KEGG: ypi:YpsIP31758_2344 proline iminopeptidase YP_001872207.1 PFAM: DNA polymerase II beta subunit; KEGG: ypi:YpsIP31758_2343 DNA polymerase III, theta subunit YP_001872208.1 PFAM: Ferritin Dps family protein; KEGG: ypp:YPDSF_1340 ferritin YP_001872209.1 PFAM: copper resistance protein CopC; KEGG: ypp:YPDSF_1339 copper resistance protein YP_001872210.1 PFAM: copper resistance D domain protein; KEGG: ypp:YPDSF_1338 copper resistance protein D YP_001872211.1 KEGG: ypp:YPDSF_1337 hypothetical protein YP_001872212.1 PFAM: protein of unknown function DUF1493; KEGG: ypi:YpsIP31758_2336 hypothetical protein YP_001872213.1 PFAM: transposase mutator type; KEGG: ypp:YPDSF_2212 transposase for the IS285 insertion element YP_001872214.1 KEGG: ypp:YPDSF_1335 membrane protein YP_001872216.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; Yersinia has 2 copies of flhB; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella YP_001872217.1 membrane protein involved in the flagellar export apparatus YP_001872218.1 PFAM: flagellar FlhE family protein; KEGG: ypi:YpsIP31758_2332 flagellar protein FlhE YP_001872219.1 PFAM: Ig domain protein group 1 domain protein; Intimin domain protein; Invasin region 3; KEGG: yps:YPTB1668 putative invasin YP_001872220.1 PFAM: FlgN family protein; KEGG: ypm:YP_1597 flagella synthesis protein FlgN YP_001872221.1 regulates the flagellar specific sigma28 transcription factor YP_001872222.1 required for the assembly of the flagellar basal body P-ring YP_001872223.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001872224.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001872225.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001872226.1 the hook connects flagellar basal body to the flagellar filament YP_001872227.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Yersinia contains two copies of this and other flagella genes YP_001872228.1 makes up the distal portion of the flagellar basal body rod YP_001872229.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_001872230.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001872231.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001872232.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001872233.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes YP_001872234.1 PFAM: putative sugar-binding domain protein; KEGG: ypi:YpsIP31758_2312 putative sugar-binding domain protein YP_001872235.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: yps:YPTB1684 short chain dehydrogenase YP_001872237.1 PFAM: inner-membrane translocator; KEGG: ypa:YPA_1187 putative sugar transport system permease protein YP_001872238.1 KEGG: ypp:YPDSF_1311 sugar-binding periplasmic protein YP_001872239.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB1687 ABC sugar transporter, ATP-binding subunit YP_001872240.1 PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_2307 carbohydrate uptake ABC transporter 2 (CUT2) family, permease protein YP_001872241.1 PFAM: PfkB domain protein; KEGG: yps:YPTB1689 putative sugar kinase YP_001872242.1 KEGG: yps:YPTB1690 hypothetical protein YP_001872244.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001872245.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_001872246.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001872247.1 PFAM: flagellar biosynthesis protein FliO; KEGG: ypp:YPDSF_1303 flagellar protein FliO YP_001872248.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001872249.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001872250.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001872251.1 PFAM: flagellar hook-length control protein; KEGG: yps:YPTB1698 flagellar hook-length control protein FliK YP_001872252.1 rod/hook and filament chaperone YP_001872253.1 involved in type III protein export during flagellum assembly YP_001872254.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001872255.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001872256.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001872257.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_001872258.1 KEGG: yps:YPTB1706 hypothetical protein YP_001872259.1 TIGRFAM: death-on-curing family protein; PFAM: Death-on-curing protein; KEGG: ypp:YPDSF_1291 hypothetical protein YP_001872260.1 PFAM: HhH-GPD family protein; KEGG: ypp:YPDSF_1290 glycosidase YP_001872261.1 PFAM: histidine kinase HAMP region domain protein; SMART: metal-dependent phosphohydrolase HD region; KEGG: ypi:YpsIP31758_2287 HAMP domain protein YP_001872262.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ypp:YPDSF_1288 AraC-family transcriptional regulatory protein YP_001872263.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_001872264.1 flagellin specific chaperone YP_001872265.1 involved in flagellin assembly YP_001872266.1 structural flagella protein YP_001872267.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001872268.1 KEGG: ypi:YpsIP31758_2279 hypothetical protein YP_001872269.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_001872270.1 catalyzes the formation of pyruvate from D-cysteine YP_001872271.1 PFAM: extracellular solute-binding protein family 3; SMART: ionotropic glutamate receptor; KEGG: ypn:YPN_2277 cystine-binding periplasmic protein YP_001872272.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2273 amino acid ABC transporter, permease protein YP_001872273.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypp:YPDSF_1277 amino-acid ABC transporter (ATP-binding protein) YP_001872274.1 KEGG: ypi:YpsIP31758_2271 hypothetical protein YP_001872275.1 KEGG: ypp:YPDSF_1276 hypothetical protein YP_001872276.1 KEGG: yps:YPTB1722 hypothetical protein YP_001872278.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_001872279.1 KEGG: ypp:YPDSF_1273 membrane protein YP_001872280.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: ypp:YPDSF_1272 proline permease YP_001872281.1 PFAM: iron permease FTR1; KEGG: ypp:YPDSF_1271 membrane protein YP_001872282.1 KEGG: ypi:YpsIP31758_2263 hypothetical protein YP_001872283.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: yps:YPTB1727 hypothetical protein YP_001872284.1 stationary phase protein that binds TrpR repressor YP_001872285.1 PFAM: Kelch repeat-containing protein; Kelch repeat protein; KEGG: ypp:YPDSF_1267 hypothetical protein YP_001872286.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_001872287.1 PFAM: virulence-related outer membrane protein; KEGG: yps:YPTB1731 attachment invasion locus protein YP_001872288.1 KEGG: ypp:YPDSF_1264 membrane protein YP_001872289.1 PFAM: GlpM family protein; KEGG: ypp:YPDSF_1263 membrane protein YP_001872290.1 KEGG: ypi:YpsIP31758_2254 hypothetical protein YP_001872291.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001872292.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001872293.1 TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: ypp:YPDSF_1259 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001872294.1 PFAM: transcriptional activator Ogr/delta; KEGG: ypi:YpsIP31758_2194 phage transcriptional activator, Ogr/delta YP_001872295.1 PFAM: late control D family protein; KEGG: yps:YPTB1835 bacteriophage P2 gpD protein YP_001872296.1 PFAM: P2 GpU family protein; KEGG: yps:YPTB1836 putative bacteriophage P2 tail protein YP_001872297.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: yps:YPTB1837 putative tail fiber component T of bacteriophage P2 YP_001872298.1 PFAM: tail E family protein; KEGG: ypi:YpsIP31758_2189 tail protein YP_001872299.1 TIGRFAM: phage major tail tube protein; PFAM: major tail tube protein; KEGG: yps:YPTB1840 putative P2 tail tube protein YP_001872300.1 PFAM: tail sheath protein; KEGG: yps:YPTB1841 putative bacteriophage P2 tail sheath protein YP_001872301.1 KEGG: yps:YPTB1842 hypothetical protein YP_001872302.1 KEGG: yps:YPTB1843 hypothetical protein YP_001872303.1 TIGRFAM: phage tail protein I; PFAM: tail protein I; KEGG: yps:YPTB1844 putative bacteriophage P2 protein YP_001872304.1 PFAM: Baseplate J family protein; KEGG: yps:YPTB1845 putative bacteriophage P2 related protein YP_001872305.1 PFAM: GPW/gp25 family protein; KEGG: yps:YPTB1846 putative phage-related protein YP_001872306.1 TIGRFAM: phage baseplate assembly protein V; PFAM: baseplate assembly protein V; KEGG: yps:YPTB1847 Orf32; P2 V homolog; baseplate protein YP_001872307.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: ypi:YpsIP31758_1346 hypothetical protein YP_001872308.1 KEGG: yps:YPTB1564 hypothetical protein YP_001872310.1 TIGRFAM: phage virion morphogenesis protein; PFAM: virion morphogenesis (putative tail completion) protein; KEGG: yps:YPTB1849 putative O protein YP_001872311.1 PFAM: P2 phage tail completion R family protein; KEGG: yps:YPTB1850 gpR [Enterobacteria phage P2] YP_001872312.1 KEGG: yps:YPTB1851 putative (AB008550) orf12; similar to LysB gene YP_001872313.1 KEGG: yps:YPTB1852 bacteriophage P7 related protein YP_001872314.1 KEGG: yps:YPTB1853 hypothetical protein YP_001872315.1 PFAM: tail X family protein; KEGG: yps:YPTB1854 putative WPhiphage-related tail protein YP_001872316.1 PFAM: head completion protein; KEGG: yps:YPTB1855 putative orf4 of phage P2 (gene L) YP_001872317.1 PFAM: small terminase subunit; KEGG: yps:YPTB1856 putative R protein bacteriophage 186 gb|AAC34151.1| YP_001872318.1 TIGRFAM: phage major capsid protein, P2 family; PFAM: major capsid protein P2; KEGG: yps:YPTB1857 putative major capsid protein YP_001872319.1 PFAM: capsid scaffolding; KEGG: yps:YPTB1858 similar to V protein phage 186 YP_001872320.1 PFAM: protein of unknown function DUF264; putative terminase ATPase subunit; KEGG: yps:YPTB1859 similar to gpP phage P2 terminase YP_001872321.1 TIGRFAM: phage portal protein, PBSX family; PFAM: portal protein; KEGG: yps:YPTB1860 similar to capsid portal protein bacteriophage 186 YP_001872324.1 KEGG: yps:YPTB1861 putative bacteriophage protein GP46 YP_001872325.1 KEGG: yen:YE0862 hypothetical phage-related protein YP_001872326.1 PFAM: replication gene A; KEGG: yps:YPTB1862 putative phage replication protein YP_001872327.1 PFAM: C-5 cytosine-specific DNA methylase; KEGG: sgl:SG0727 phage methyltransferase YP_001872328.1 TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: yps:YPTB1863 putative DNA adenine methylase YP_001872329.1 PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: yps:YPTB1864 similar to Orf81 bacteriophage 186 YP_001872330.1 KEGG: yps:YPTB1865 hypothetical protein YP_001872331.1 KEGG: yps:YPTB1866 hypothetical protein YP_001872332.1 KEGG: yps:YPTB1867 hypothetical protein YP_001872334.1 KEGG: yps:YPTB1868 hypothetical protein YP_001872335.1 KEGG: yen:YE0856 hypothetical phage-related protein YP_001872336.1 KEGG: yps:YPTB1869 putative DNA-binding protein YP_001872337.1 KEGG: ecs:ECs5465 hypothetical protein YP_001872338.1 PFAM: helix-turn-helix domain protein; KEGG: yps:YPTB1870 putative prophage transcriptional regulator YP_001872339.1 KEGG: yps:YPTB1871 similar to hypothetical protein YP_001872340.1 KEGG: yps:YPTB1872 putative bacteriophage integrase YP_001872341.1 KEGG: yps:YPTB1873 hypothetical protein YP_001872342.1 KEGG: yps:YPTB1874 putative bacteriophage integrase YP_001872343.1 PFAM: integrase family protein; KEGG: yps:YPTB1875 putative prophage integrase YP_001872344.1 KEGG: ypi:YpsIP31758_2250 site-specific recombinase, phage integrase family YP_001872346.1 KEGG: yps:YPTB1879 hypothetical protein YP_001872348.1 KEGG: ypg:YpAngola_A2060 hypothetical protein YP_001872349.1 KEGG: ypg:YpAngola_A2061 hypothetical protein YP_001872350.1 KEGG: yps:YPTB1880 hypothetical protein YP_001872351.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: yps:YPTB1881 hypothetical protein YP_001872352.1 PFAM: Integrase catalytic region; KEGG: yps:YPTB1882 putative transposase YP_001872353.1 PFAM: transposase IS3/IS911 family protein; KEGG: yps:YPTB1883 hypothetical protein YP_001872355.1 PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB1884 possible MFS Superfamliy multidrug-efflux transporter YP_001872356.1 PFAM: UBA/THIF-type NAD/FAD binding protein; Methyltransferase type 11; Methyltransferase type 12; KEGG: yps:YPTB1885 possible ThiF family YP_001872357.1 PFAM: Methyltransferase type 12; KEGG: yps:YPTB1886 hypothetical protein YP_001872358.1 KEGG: yps:YPTB1887 hypothetical protein YP_001872359.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: yps:YPTB1888 hypothetical protein YP_001872360.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: yps:YPTB1889 possible diaminopimelate decarboxylase YP_001872361.1 KEGG: yps:YPTB1890 putative similar to ribosomal-protein-alanine N-acetyltransferase YP_001872362.1 KEGG: yps:YPTB1891 weak similarity to Vibrio transposase YP_001872363.1 PFAM: Integrase catalytic region; KEGG: yps:YPTB1892 putative transposase YP_001872364.1 KEGG: ypg:YpAngola_A2064 ISAfe5, transposase OrfA YP_001872365.1 KEGG: ypg:YpAngola_A2065 gpF1 YP_001872366.1 KEGG: yps:YPTB1895 hypothetical protein YP_001872367.1 KEGG: yps:YPTB1896 hypothetical protein YP_001872368.1 KEGG: ypp:YPDSF_1250 membrane protein YP_001872369.1 PFAM: GPW/gp25 family protein; KEGG: ypp:YPDSF_1248 hypothetical protein YP_001872370.1 KEGG: yps:YPTB1900 hypothetical protein YP_001872371.1 PFAM: protein of unknown function DUF497; KEGG: yps:YPTB1901 hypothetical protein YP_001872372.1 KEGG: ypp:YPDSF_1245 hypothetical protein YP_001872373.1 KEGG: ypp:YPDSF_1244 hypothetical protein YP_001872374.1 PFAM: transposase mutator type; KEGG: ypp:YPDSF_1243 hypothetical protein YP_001872375.1 KEGG: yps:YPTB1905 putative transposase (IS285) YP_001872377.1 KEGG: ypi:YpsIP31758_2178 hypothetical protein YP_001872378.1 KEGG: yps:YPTB1907 hypothetical protein YP_001872379.1 KEGG: ypp:YPDSF_1239 hypothetical protein YP_001872380.1 KEGG: ypp:YPDSF_1237 hypothetical protein YP_001872381.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: ypp:YPDSF_1236 GntR-family putative transcriptional regulatory protein YP_001872382.1 KEGG: yps:YPTB1911 hypothetical protein YP_001872383.1 KEGG: ypg:YpAngola_A2080 hypothetical protein YP_001872384.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: yps:YPTB1912 putative oxidoreductase YP_001872385.1 PFAM: extracellular solute-binding protein family 1; KEGG: yps:YPTB1913 ABC transporter, perplasmic sorbitol binding protein YP_001872386.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_1233 binding-protein-dependent transport system, inner membrane component YP_001872387.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yps:YPTB1915 ABC sugar (sorbitol/trehalose/maltose) transporter, permease subunit YP_001872388.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: yps:YPTB1916 ABC sugar transporter, ATP binding subunit YP_001872389.1 PFAM: Pili assembly chaperone, N-terminal; KEGG: ypi:YpsIP31758_2167 gram-negative pili assembly chaperone YP_001872390.1 KEGG: yps:YPTB1918 hypothetical protein YP_001872391.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: yps:YPTB1919 putative outer membrane fimbrial usher porin YP_001872392.1 PFAM: Pili assembly chaperone, N-terminal; KEGG: yps:YPTB1920 probable pili assembly chaperone YP_001872393.1 PFAM: Fimbrial protein; KEGG: ypa:YPA_1300 fimbrial protein YP_001872394.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: extracellular solute-binding protein family 3; KEGG: yps:YPTB1922 possible two-component sensor YP_001872395.1 PFAM: regulatory protein LuxR; response regulator receiver; KEGG: ypp:YPDSF_1199 two-component response regulator YP_001872396.1 PFAM: acetyl-CoA hydrolase/transferase; KEGG: yps:YPTB1924 putative 4-hydroxybutyrate coenzyme A transferase YP_001872397.1 PFAM: MaoC domain protein dehydratase; KEGG: ypm:YP_1669 putative transcriptional regulator YP_001872398.1 PFAM: HpcH/HpaI aldolase; KEGG: ypp:YPDSF_1196 citrate lyase beta chain YP_001872399.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_2155 substrate-binding transcriptional regulator, LysR family YP_001872400.1 KEGG: ypi:YpsIP31758_2154 hypothetical protein YP_001872401.1 KEGG: yps:YPTB1929 hypothetical protein YP_001872402.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_1192 sugar transporter YP_001872403.1 PFAM: amidohydrolase 2; KEGG: yps:YPTB1931 putative dicarboxylic acid hydrolase YP_001872404.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypp:YPDSF_1190 LysR-family transcriptional regulatory protein YP_001872405.1 Part of the NQR complex which has six subunits NqrA, NqrB, NqrC, NqrD, NqrE and NqrF. NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol YP_001872406.1 PFAM: aminotransferase class I and II; KEGG: ypp:YPDSF_1188 aminotransferase YP_001872407.1 PFAM: amino acid permease-associated region; KEGG: ypp:YPDSF_1187 L-asparagine permease YP_001872408.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: ypp:YPDSF_1186 DeoR-family transcriptional regulatory protein YP_001872409.1 catalyzes the formation of glutamate from glutamine YP_001872410.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_1183 membrane protein YP_001872411.1 PFAM: iron permease FTR1; KEGG: yps:YPTB1939 high-affinity Fe2+/Pb2+ permease YP_001872412.1 KEGG: ypp:YPDSF_1180 hypothetical protein YP_001872414.1 PFAM: YHS domain protein; KEGG: ypi:YpsIP31758_2139 YHS domain protein YP_001872415.1 PFAM: protein of unknown function DUF214; KEGG: ypa:YPA_1327 hypothetical protein YP_001872416.1 PFAM: protein of unknown function DUF214; KEGG: yps:YPTB1943 putative ABC transporter, permease subunit YP_001872417.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_2136 ABC transporter, ATP-binding protein YP_001872418.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: ypi:YpsIP31758_2135 thiol-disulfide oxidoreductase YP_001872419.1 PFAM: cytochrome c class I; KEGG: ypp:YPDSF_1174 cytochrome YP_001872420.1 with TehA confers resistance to tellurite YP_001872421.1 PFAM: creatinase; peptidase M24; KEGG: ypi:YpsIP31758_2132 peptidase, M24 family YP_001872422.1 in Yersinia this protein is important for biofilm formation and hemin adsorption YP_001872423.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export YP_001872424.1 predicted polysaccharide polymerase involved in biofilm formation; in Escherichia coli the related protein PgaC is required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; in Yersinia the HmsR protein is an inner membrane protein YP_001872425.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption YP_001872426.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yps:YPTB1953 putative acetyltransferase YP_001872427.1 KEGG: ypp:YPDSF_1166 hypothetical protein YP_001872428.1 PFAM: PhoH family protein; KEGG: ypp:YPDSF_1165 phosphate starvation-inducible protein YP_001872429.1 TIGRFAM: calcium/proton exchanger; PFAM: sodium/calcium exchanger membrane region; KEGG: ypa:YPA_1341 calcium/proton antiporter YP_001872430.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: yps:YPTB1957 nitrate/nitrite sensor protein NarX YP_001872431.1 PFAM: aminotransferase class I and II; KEGG: ypp:YPDSF_1162 GntR-family regulatory protein YP_001872433.1 KEGG: ypm:YP_1706 hypothetical protein YP_001872434.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_001872435.1 TIGRFAM: arginine/ornithine succinyltransferase subunit; arginine N-succinyltransferase; PFAM: arginine N-succinyltransferase beta subunit; KEGG: yps:YPTB1960 arginine succinyltransferase YP_001872436.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001872437.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001872438.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001872439.1 PFAM: porin Gram-negative type; KEGG: ypi:YpsIP31758_2115 outer membrane protein N YP_001872440.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: ypp:YPDSF_2254 insertion sequence IS100, ATP-binding protein YP_001872441.1 PFAM: Integrase catalytic region; Resolvase helix-turn-helix domain protein; KEGG: yps:YPTB3875 putative transposase YP_001872442.1 PFAM: porin Gram-negative type; KEGG: ypi:YpsIP31758_2115 outer membrane protein N YP_001872443.1 PFAM: N-formylglutamate amidohydrolase; KEGG: yps:YPTB1965 putative N-formylglutamate amidohydrolase YP_001872444.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001872445.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: yps:YPTB1967 putative GntR-family transcriptional regulatory protein YP_001872446.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_001872447.1 PFAM: protein of unknown function DUF886; KEGG: yps:YPTB1969 hypothetical protein YP_001872448.1 PFAM: Chorismate binding-like; KEGG: yps:YPTB1970 hypothetical protein YP_001872449.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: yps:YPTB1971 putative 3-oxoacyl-(acyl-carrier-protein) synthase III YP_001872450.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ypi:YpsIP31758_2107 NAD-dependent epimerase/dehydratase family protein YP_001872451.1 PFAM: beta-lactamase domain protein; KEGG: yps:YPTB1973 hypothetical protein YP_001872452.1 TIGRFAM: adenylate-forming enzyme; KEGG: yps:YPTB1974 putative coenzyme synthetase YP_001872453.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: ypi:YpsIP31758_2103 NAD dependent epimerase/dehydratase family protein YP_001872454.1 KEGG: yps:YPTB1976 putative glycosyl transferase YP_001872455.1 KEGG: yps:YPTB1977 hypothetical protein YP_001872456.1 KEGG: yps:YPTB1978 putative glycosyl transferase YP_001872457.1 KEGG: yps:YPTB1979 hypothetical protein YP_001872458.1 KEGG: yps:YPTB1980 hypothetical protein YP_001872459.1 PFAM: Sel1 domain protein repeat-containing protein; MORN variant repeat protein; KEGG: yps:YPTB1981 hypothetical protein YP_001872461.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: yps:YPTB1982 hypothetical protein YP_001872462.1 PFAM: Ribose/galactose isomerase; KEGG: ypi:YpsIP31758_2095 hypothetical protein YP_001872463.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ypp:YPDSF_1131 hypothetical protein YP_001872464.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Male sterility domain; KR domain protein; KEGG: yps:YPTB1985 putative dehydrogenase YP_001872466.1 KEGG: ypi:YpsIP31758_2092 hypothetical protein YP_001872467.1 KEGG: ypi:YpsIP31758_2091 hypothetical protein YP_001872468.1 KEGG: yps:YPTB1988 hypothetical protein YP_001872469.1 KEGG: yps:YPTB1989 hypothetical protein YP_001872470.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: ypi:YpsIP31758_2087 cupin domain protein YP_001872471.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: yps:YPTB1991 putative decarboxylase YP_001872472.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yps:YPTB1992 putative two-component system sensor protein YP_001872473.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: yps:YPTB1993 transcriptional activator YP_001872474.1 KEGG: yps:YPTB1994 hypothetical protein YP_001872475.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001872476.1 KEGG: yps:YPTB1996 hypothetical protein YP_001872477.1 KEGG: yps:YPTB1997 hypothetical protein YP_001872478.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001872479.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001872480.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_001872481.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001872483.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001872484.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_001872485.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001872486.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001872487.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_001872488.1 PFAM: Invasion gene expression up-regulator SirB; KEGG: ypi:YpsIP31758_2064 SirB family protein YP_001872489.1 KEGG: ypi:YpsIP31758_2063 SirB1 protein YP_001872490.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001872491.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_001872492.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: ypi:YpsIP31758_2060 glycerophosphoryl diester phosphodiesterase family protein YP_001872493.1 PFAM: extracellular solute-binding protein family 1; KEGG: yps:YPTB2013 possible ABC transporter, periplasmic substrate binding protein YP_001872494.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_2058 putative spermidine/putrescine ABC transporter, permease protein YP_001872495.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yps:YPTB2015 putative ABC transporter, permease subunit YP_001872496.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_2056 putative spermidine/putrescine ABC transporter, ATP-binding protein YP_001872497.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: ypi:YpsIP31758_2055 glycerophosphoryl diester phosphodiesterase family YP_001872498.1 PFAM: ROK family protein; KEGG: ypi:YpsIP31758_2054 ROK family protein YP_001872499.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: ypi:YpsIP31758_2053 putative phosphoesterase YP_001872500.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: ypi:YpsIP31758_2052 cytoplasmic chaperone, TorD family YP_001872501.1 PFAM: protein of unknown function DUF1439; KEGG: ypi:YpsIP31758_2051 putative lipoprotein YP_001872502.1 Confers resistance to norfloxacin and enoxacin YP_001872503.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ypp:YPDSF_1082 ribosomal-protein-alanine acetyltransferase YP_001872504.1 PFAM: protein of unknown function DUF480; KEGG: ypi:YpsIP31758_2048 hypothetical protein YP_001872505.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: ypp:YPDSF_1081 oxidoreductase YP_001872506.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: yps:YPTB2026 virulence factor MviN, possible MOP Superfamliy efflux pump YP_001872507.1 PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: yps:YPTB2027 hemolysin activator protein HlyB, TPS secretion family YP_001872508.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001872509.1 PFAM: protein of unknown function DUF991; KEGG: yps:YPTB2030 hypothetical protein YP_001872510.1 PFAM: CutC family protein; KEGG: yps:YPTB2031 copper homeostasis protein CutC YP_001872511.1 TIGRFAM: methyltransferase; PFAM: methyltransferase putative; Methyltransferase type 11; KEGG: yps:YPTB2032 hypothetical protein YP_001872512.1 TIGRFAM: methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ypp:YPDSF_1072 hypothetical protein YP_001872513.1 KEGG: ypi:YpsIP31758_2037 hypothetical protein YP_001872514.1 PFAM: protein of unknown function DUF72; KEGG: yps:YPTB2035 hypothetical protein YP_001872515.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001872516.1 converts dATP to dAMP and pyrophosphate YP_001872517.1 PFAM: protein of unknown function DUF28; KEGG: ypp:YPDSF_1067 hypothetical protein YP_001872518.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001872519.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001872520.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001872521.1 involved in transport of zinc(II) with ZnuA and C YP_001872522.1 involved in transport of zinc(II) with ZnuA and C YP_001872523.1 involved in transport of zinc(II) with ZnuA and C YP_001872524.1 PFAM: Peptidoglycan-binding LysM; Opacity-associated protein A; Opacity-associated protein A domain protein; Peptidase M23; KEGG: ypp:YPDSF_1060 M23/M37 peptidase-family protein YP_001872525.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001872526.1 KEGG: ypi:YpsIP31758_3030 hypothetical protein YP_001872527.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001872528.1 Represses the expression of the zwf, eda, glp and gap YP_001872529.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001872531.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001872532.1 PFAM: small multidrug resistance protein; KEGG: yps:YPTB2051 DMT superfamily drug efflux pump YP_001872533.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_001872534.1 PFAM: Endoribonuclease L-PSP; KEGG: ypp:YPDSF_1052 hypothetical protein YP_001872535.1 SMART: helicase c2; DEAD-like helicases; KEGG: ypi:YpsIP31758_2017 hypothetical protein YP_001872536.1 PFAM: peptidase M22 glycoprotease; KEGG: yps:YPTB2055 hypothetical protein YP_001872537.1 TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: ypn:YPN_1550 lipoprotein YP_001872538.1 Activates fatty acids by binding to coenzyme A YP_001872539.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: ypp:YPDSF_1046 ribonuclease D YP_001872540.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001872541.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_001872542.1 blocks the formation of polar Z-ring septums YP_001872543.1 PFAM: protein of unknown function DUF709; KEGG: ypi:YpsIP31758_2009 hypothetical protein YP_001872544.1 TIGRFAM: lytic murein transglycosylase; KEGG: ypi:YpsIP31758_2008 lytic murein transglycosylase YP_001872545.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: ypp:YPDSF_1040 fumarylacetoacetate hydrolase family protein YP_001872546.1 PFAM: protein of unknown function UPF0153; KEGG: ypi:YpsIP31758_2006 hypothetical protein YP_001872547.1 PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB2066 hypothetical protein YP_001872548.1 PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: yps:YPTB2067 putative aminotransferase YP_001872549.1 KEGG: ypp:YPDSF_0992 hypothetical protein YP_001872550.1 KEGG: ypi:YpsIP31758_2002 hypothetical protein YP_001872552.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001872553.1 involved in regulation of intracellular pH under alkaline conditions YP_001872554.1 Multifunctional regulator of fatty acid metabolism YP_001872555.1 PFAM: SpoVR family protein; KEGG: ypi:YpsIP31758_1998 SpoVR family protein YP_001872556.1 catalyzes the oxidative deamination of D-amino acids YP_001872557.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_1996 drug resistance transporter, Bcr/CflA family YP_001872558.1 PFAM: Pirin domain protein; KEGG: yps:YPTB2076 hypothetical protein YP_001872559.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypp:YPDSF_0983 LysR-family transcriptional regulatory protein YP_001872560.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypi:YpsIP31758_1993 integral membrane protein YP_001872561.1 PFAM: protein of unknown function DUF444; KEGG: ypi:YpsIP31758_1992 hypothetical protein YP_001872563.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: ypi:YpsIP31758_1991 PrkA serine protein kinase YP_001872564.1 PFAM: MltA-interacting MipA family protein; KEGG: ypg:YpAngola_A2353 MltA-interacting protein YP_001872565.1 PFAM: Aldose 1-epimerase; KEGG: yps:YPTB2082 hypothetical protein YP_001872566.1 TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; KEGG: ypn:YPN_1623 glyceraldehyde 3-phosphate dehydrogenase A YP_001872567.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_001872568.1 PFAM: protein of unknown function DUF1315; KEGG: ypp:YPDSF_0975 hypothetical protein YP_001872569.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_001872570.1 converts asparagine to aspartate and ammonia YP_001872571.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_001872572.1 PFAM: nitroreductase; KEGG: ypp:YPDSF_0971 nitroreductase YP_001872573.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001872575.1 decatenates replicating daughter chromosomes YP_001872576.1 PFAM: protein of unknown function DUF1496; KEGG: ypp:YPDSF_0968 hypothetical protein YP_001872577.1 PFAM: NUDIX hydrolase; KEGG: ypp:YPDSF_0967 pyrophosphohydrolase YP_001872578.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001872579.1 KEGG: ypi:YpsIP31758_1975 hypothetical protein YP_001872580.1 PFAM: regulatory protein LysR; KEGG: ypi:YpsIP31758_1974 transcriptional regulator, LysR family YP_001872581.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001872582.1 PFAM: SEC-C motif domain protein; KEGG: ypg:YpAngola_A2333 sec-C motif-containing protein YP_001872583.1 PFAM: response regulator receiver; KEGG: yps:YPTB2099 response regulator of RpoS YP_001872584.1 TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: ypi:YpsIP31758_1968 UDP-glucose/GDP-mannose dehydrogenase family protein YP_001872586.1 KEGG: ypg:YpAngola_A2329 hypothetical protein YP_001872587.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: ypi:YpsIP31758_1966 DNA-binding protein H-NS YP_001872588.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001872589.1 PFAM: iron-containing alcohol dehydrogenase; Aldehyde Dehydrogenase_; KEGG: ypp:YPDSF_0956 aldehyde-alcohol dehydrogenase YP_001872590.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: ypi:YpsIP31758_1962 hypothetical protein YP_001872591.1 PFAM: extracellular solute-binding protein family 5; KEGG: yps:YPTB2105 ABC transporter, periplasmic oligopeptide-binding protein OppA YP_001872592.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_0953 oligopeptide transport system permease protein YP_001872593.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1958 oligopeptide ABC transporter, permease protein OppC YP_001872594.1 KEGG: ypp:YPDSF_0951 oligopeptide transport ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001872595.1 KEGG: ypp:YPDSF_0950 oligopeptide transport ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001872596.1 KEGG: ypi:YpsIP31758_1955 hypothetical protein YP_001872597.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_001872598.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001872599.1 KEGG: yps:YPTB2112 hypothetical protein YP_001872600.1 PFAM: virulence-related outer membrane protein; KEGG: ypi:YpsIP31758_1951 Ail/Lom family protein YP_001872601.1 KEGG: ypi:YpsIP31758_1950 hypothetical protein YP_001872602.1 KEGG: ypi:YpsIP31758_1949 hypothetical protein YP_001872603.1 KEGG: yps:YPTB2115 hypothetical protein YP_001872604.2 PFAM: YCII-related; KEGG: ypi:YpsIP31758_1947 YciI domain protein YP_001872606.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_001872607.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_001872608.1 Involved in cell division; probably involved in intracellular septation YP_001872610.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; sulphate transporter; KEGG: ypi:YpsIP31758_1943 sulfate permease family protein YP_001872611.1 PFAM: protein of unknown function UPF0259; KEGG: ypp:YPDSF_0935 membrane protein YP_001872612.1 receptor for colicin S4 YP_001872613.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: ypi:YpsIP31758_1939 putative phospholipid-binding domain protein YP_001872614.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001872615.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001872616.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001872617.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001872618.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001872619.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001872620.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: ypp:YPDSF_0924 hypothetical protein YP_001872621.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: ypp:YPDSF_0923 hypothetical protein YP_001872622.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_001872623.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001872624.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ypp:YPDSF_0920 short chain dehydrogenase YP_001872625.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001872626.1 KEGG: yps:YPTB2139 hypothetical protein YP_001872627.1 KEGG: ypn:YPN_1685 hypothetical protein YP_001872628.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001872629.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001872630.1 KEGG: ypg:YpAngola_A2229 hypothetical protein YP_001872631.1 Catalyzes the conversion of citrate to isocitrate YP_001872632.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001872633.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: ypi:YpsIP31758_1917 PAP2 family protein YP_001872634.1 PFAM: protein of unknown function DUF1049; KEGG: ypm:YP_2023 hypothetical protein YP_001872635.1 PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ypi:YpsIP31758_1915 tetratricopeptide repeat protein YP_001872636.1 KEGG: ypi:YpsIP31758_1914 hypothetical protein YP_001872637.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001872638.1 involved in start site selection during the initiation of translation YP_001872639.1 KEGG: ypn:YPN_1698 osmotically inducible lipoprotein B precursor YP_001872640.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_001872641.1 KEGG: ypi:YpsIP31758_1909 hypothetical protein YP_001872642.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_001872643.1 PFAM: protein of unknown function DUF466; KEGG: ypp:YPDSF_0901 hypothetical protein YP_001872644.1 PFAM: carbon starvation protein CstA; KEGG: ypp:YPDSF_0900 carbon starvation protein A YP_001872645.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_001872646.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_1903 transporter, major facilitator family YP_001872647.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; KEGG: yps:YPTB2159 hypothetical protein YP_001872648.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines YP_001872649.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001872650.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001872651.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001872652.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: yps:YPTB2164 putative AraC-family transcriptional regulatory protein YP_001872653.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001872654.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001872655.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: ypn:YPN_1714 membrane protein YP_001872656.1 KEGG: ypp:YPDSF_0888 membrane protein YP_001872657.1 KEGG: yps:YPTB2169 putative ABC RTX toxin transporter, fused ATP binding/permease domains; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001872658.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: ypi:YpsIP31758_1890 type I secretion membrane fusion protein, HlyD family protein YP_001872659.1 KEGG: yps:YPTB2171 putative ABC RTX toxin transporter, fused ATP binding/permease domains; TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase YP_001872660.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_001872661.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_001872662.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: yps:YPTB2174 ABC transporter, periplasmic L-arabinose-binding protein AraF YP_001872663.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001872664.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001872665.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_001872666.1 PFAM: Semialdehyde dehydrogenase NAD - binding; oxidoreductase domain protein; Oxidoreductase domain; KEGG: ypp:YPDSF_0874 oxidoreductase YP_001872667.1 KEGG: ypi:YpsIP31758_1880 putative sodium/bile acid symporter family protein YP_001872668.1 catalyzes the formation of inosine from adenosine YP_001872669.1 KEGG: yps:YPTB2181 hypothetical protein YP_001872670.1 KEGG: yps:YPTB2182 hypothetical protein YP_001872671.1 KEGG: bxe:Bxe_A4152 PTS system, N-acetylglucosamine-specific IIBC component YP_001872672.1 PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: yps:YPTB2183 putative transcriptional regulator YP_001872673.1 PFAM: protein of unknown function DUF945; KEGG: ypi:YpsIP31758_1875 hypothetical protein YP_001872674.1 TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; KEGG: yps:YPTB2185 mannose-6-phosphate isomerase YP_001872675.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001872676.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_001872677.1 PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB2188 putative MFS multidrug efflux pump YP_001872678.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB2189 hypothetical protein YP_001872679.1 PFAM: ROK family protein; KEGG: ypa:YPA_1628 putative ROK family transcriptional regulatory protein YP_001872680.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001872681.1 PFAM: Chloride channel core; KEGG: ypp:YPDSF_0863 membrane protein YP_001872682.1 PFAM: protein of unknown function DUF1161; KEGG: ypp:YPDSF_0862 hypothetical protein YP_001872683.1 PFAM: protein of unknown function DUF1283; KEGG: ypi:YpsIP31758_1865 hypothetical protein YP_001872684.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_001872685.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: yps:YPTB2196 putative transcriptional regulator YP_001872686.1 PFAM: protein of unknown function DUF1283; KEGG: ypi:YpsIP31758_1865 hypothetical protein YP_001872687.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_001872688.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: AAA ATPase; KEGG: yps:YPTB2196 putative transcriptional regulator YP_001872689.1 PFAM: Aldehyde Dehydrogenase_; KEGG: yps:YPTB2197 probable aldehyde dehydrogenase YP_001872690.1 KEGG: yps:YPTB2198 hypothetical protein YP_001872691.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: yps:YPTB2199 possible DMT superfamily metabolite efflux pump YP_001872693.1 KEGG: ype:YPO2282 hypothetical protein YP_001872694.1 PFAM: aminotransferase class I and II; KEGG: ypi:YpsIP31758_1857 aminotransferase, classes I and II YP_001872695.1 PFAM: Na+/H+ antiporter NhaC; KEGG: ypi:YpsIP31758_1856 Na+/H+ antiporter NhaC YP_001872697.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypm:YP_2067 putative LacI-family transcriptional regulatory protein YP_001872698.1 KEGG: ypi:YpsIP31758_1854 hypothetical protein YP_001872699.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: yps:YPTB2204 putative ABC transporter, periplasmic ribose/sugar-binding protein YP_001872700.1 PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_1852 ribose ABC transporter, permease protein YP_001872701.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_1851 ribose ABC transporter, ATP-binding protein YP_001872702.1 KEGG: yps:YPTB2207 hypothetical protein YP_001872704.1 KEGG: ypi:YpsIP31758_1849 ABC transporter, periplasmic substrate-binding protein YP_001872705.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1848 ABC transporter , permease protein YP_001872706.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypg:YpAngola_A2274 ABC transporter, ATP-binding protein YP_001872707.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001872708.1 KEGG: ypi:YpsIP31758_1844 hypothetical protein YP_001872709.1 PFAM: virulence protein SrfB; KEGG: ypi:YpsIP31758_1843 putative virulence factor SrfB YP_001872710.1 KEGG: ypi:YpsIP31758_1842 hypothetical protein YP_001872711.1 PFAM: protein of unknown function DUF1460; KEGG: ypp:YPDSF_0850 lipoprotein YP_001872712.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: yps:YPTB2216 acetolactate synthase catalytic subunit YP_001872713.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_001872714.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_001872715.1 KEGG: yps:YPTB2219 hypothetical protein YP_001872716.1 PFAM: Alkaline phosphatase; KEGG: ypp:YPDSF_0845 alkaline phosphatase precursor YP_001872717.1 TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylguanine DNA methyltransferase ribonuclease domain protein; Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: ypp:YPDSF_0844 methylated-DNA--protein-cysteine methyltransferase YP_001872718.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001872719.1 with UspC and UspD is involved in resistance to UV irradiation YP_001872720.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_001872721.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_001872722.1 PFAM: protein of unknown function DUF1471; KEGG: ypp:YPDSF_0839 hypothetical protein YP_001872723.1 TIGRFAM: arginine/ornithine antiporter; PFAM: amino acid permease-associated region; KEGG: ypp:YPDSF_0838 amino acid antiporter YP_001872724.1 KEGG: yps:YPTB2229 hypothetical protein YP_001872725.1 response regulator in two-component regulatory system with RstB YP_001872726.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ypi:YpsIP31758_1825 sensor protein RstB YP_001872727.1 PFAM: peptidase M32 carboxypeptidase Taq metallopeptidase; KEGG: ypp:YPDSF_0834 carboxypeptidase YP_001872728.1 TIGRFAM: YD repeat protein; KEGG: yps:YPTB2233 putative insecticidal toxin complex YP_001872729.1 PFAM: YceI family protein; KEGG: ypp:YPDSF_0829 hypothetical protein YP_001872730.1 PFAM: cytochrome B561; KEGG: ypi:YpsIP31758_1820 cytochrome b561 family protein YP_001872731.1 KEGG: ypn:YPN_1778 acid shock protein YP_001872732.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: yps:YPTB2238 putative pepetidase YP_001872733.1 PFAM: helix-turn-helix domain protein; KEGG: ypi:YpsIP31758_1817 DNA-binding protein YP_001872734.1 PFAM: protein of unknown function DUF891; KEGG: ypi:YpsIP31758_1816 hypothetical protein YP_001872735.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_001872736.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001872737.1 PFAM: putative sugar-binding domain protein; KEGG: ypp:YPDSF_0822 transcriptional regulatory protein YP_001872738.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: yps:YPTB2244 putative mannitol dehydrogenase YP_001872739.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_1811 hypothetical protein YP_001872740.1 KEGG: ypi:YpsIP31758_1810 putative lipoprotein YP_001872741.1 KEGG: yps:YPTB2247 hypothetical protein YP_001872742.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: yps:YPTB2248 D-lactate dehydrogenase YP_001872743.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: yps:YPTB2249 heat-inducible protein YP_001872744.1 KEGG: yps:YPTB2250 putative lipoprotein YP_001872745.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli YP_001872746.1 PFAM: small multidrug resistance protein; KEGG: ypi:YpsIP31758_1804 multidrug resistance protein, SMR family protein YP_001872747.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: ypi:YpsIP31758_1803 pyruvate:ferredoxin (flavodoxin) oxidoreductase YP_001872748.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001872749.1 KEGG: yps:YPTB2255 hypothetical protein YP_001872751.1 PFAM: regulatory protein MerR; KEGG: yps:YPTB2256 putative regulatory protein YP_001872752.1 PFAM: Mg2 transporter protein CorA family protein; KEGG: ypg:YpAngola_A2390 zinc transport protein ZntB YP_001872753.1 PFAM: extracellular solute-binding protein family 5; KEGG: yps:YPTB2258 putative ABC transporter, periplasmic murein peptide-binding protein YP_001872754.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: yps:YPTB2259 murein peptide amidase A YP_001872755.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: yps:YPTB2260 putative mandelate racemase / muconate lactonizing protein YP_001872756.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_001872757.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_001872758.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_1793 conserved hypothetical protein TIGR02293 YP_001872759.1 PFAM: RES domain protein; KEGG: yps:YPTB2264 hypothetical protein YP_001872760.1 PFAM: conserved hypothetical protein; KEGG: ypp:YPDSF_0796 membrane protein YP_001872761.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: ypi:YpsIP31758_1790 hypothetical protein YP_001872762.1 TIGRFAM: phage shock protein PspD; PFAM: shock protein PspD; KEGG: ypp:YPDSF_0794 phage shock protein YP_001872763.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_001872764.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001872765.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_001872766.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_001872767.1 PFAM: extracellular solute-binding protein family 5; KEGG: ypi:YpsIP31758_1784 peptide ABC transporter, periplasmic peptide-binding protein YP_001872768.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_0787 peptide transport system permease protein YP_001872769.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_0786 peptide transport system permease protein YP_001872770.1 KEGG: ypp:YPDSF_0785 peptide transport system ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter related; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001872771.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypp:YPDSF_0784 peptide transport system ATP-binding protein YP_001872772.1 KEGG: ypp:YPDSF_0783 hypothetical protein YP_001872773.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_001872774.1 PFAM: protein of unknown function DUF1282; KEGG: ypp:YPDSF_0781 membrane protein YP_001872775.1 KEGG: ypi:YpsIP31758_1776 hypothetical protein YP_001872776.1 PFAM: Glutathione S-transferase domain; KEGG: ypi:YpsIP31758_1775 glutathione S-transferase YP_001872777.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_001872778.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001872779.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001872780.1 PFAM: aldo/keto reductase; KEGG: yps:YPTB2289 putative aldo/keto reductase YP_001872781.1 PFAM: protein of unknown function DUF1289; KEGG: ypi:YpsIP31758_1765 hypothetical protein YP_001872782.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_001872783.1 PFAM: regulatory protein TetR; KEGG: ypi:YpsIP31758_1763 transcriptional regulator, TetR family YP_001872784.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_001872785.1 TIGRFAM: YD repeat protein; KEGG: yps:YPTB2294 insecticial toxin YP_001872786.1 TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ypi:YpsIP31758_1760 lactoylglutathione lyase YP_001872787.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001872788.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: ypi:YpsIP31758_1758 monothiol glutaredoxin GrxD YP_001872789.1 KEGG: ype:YPO2384 hypothetical protein YP_001872790.1 PFAM: NLP/P60 protein; KEGG: ypi:YpsIP31758_1757 lipoprotein, NlpC/P60 family YP_001872791.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_001872792.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_001872793.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB2301 putative DNA-binding transcriptional regulator YP_001872794.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001872795.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_001872796.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001872797.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_001872798.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001872799.1 PFAM: LPP repeat-containing protein; KEGG: ypn:YPN_1848 hypothetical protein YP_001872800.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: ypn:YPN_1853 hypothetical protein YP_001872801.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_001872802.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_001872803.1 with SufBC activates cysteine desulfurase SufS YP_001872804.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_001872805.1 with SufCD activates cysteine desulfurase SufS YP_001872806.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_001872807.1 PFAM: thioesterase superfamily protein; KEGG: ypp:YPDSF_0743 hypothetical protein YP_001872808.1 PFAM: FAD linked oxidase domain protein; KEGG: yps:YPTB2316 hypothetical protein YP_001872809.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_001872810.1 KEGG: pfa:PFF1425w RNA binding protein, putative YP_001872811.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001872812.1 PFAM: protein of unknown function DUF299; KEGG: ypp:YPDSF_0739 hypothetical protein YP_001872813.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001872814.1 PFAM: protein of unknown function UPF0061; KEGG: ypp:YPDSF_0737 hypothetical protein YP_001872815.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_001872816.1 PFAM: NLP/P60 protein; KEGG: ypp:YPDSF_0735 lipoprotein YP_001872817.1 KEGG: ypi:YpsIP31758_1731 hypothetical protein YP_001872818.1 PFAM: small multidrug resistance protein; KEGG: ypi:YpsIP31758_1730 multidrug resistance protein, SMR family YP_001872819.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_001872820.1 PFAM: polysaccharide deacetylase; KEGG: ypp:YPDSF_0731 hypothetical protein YP_001872821.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_001872822.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_001872823.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_001872824.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_001872825.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_001872826.1 with BtuD and BtuF transports vitamin B12 into the cell YP_001872827.1 KEGG: yps:YPTB2334 hypothetical protein YP_001872828.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001872829.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001872830.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001872831.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001872832.1 PFAM: ribosomal protein L35; KEGG: ypi:YpsIP31758_1714 ribosomal protein L35 YP_001872833.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001872834.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001872835.1 KEGG: ypi:YpsIP31758_1711 hypothetical protein YP_001872836.1 KEGG: ypi:YpsIP31758_1708 hypothetical protein YP_001872837.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_001872838.1 PFAM: Lytic transglycosylase catalytic; KEGG: ypp:YPDSF_0714 membrane-bound lytic murein transglycosylase YP_001872839.1 PFAM: periplasmic solute binding protein; KEGG: ypp:YPDSF_0713 periplasmic-binding protein YP_001872840.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypp:YPDSF_0712 ATP-binding transport protein YP_001872841.1 PFAM: transport system permease protein; ABC-3 protein; KEGG: ypi:YpsIP31758_1703 chelated iron ABC transporter, permease protein YfeC YP_001872842.1 PFAM: transport system permease protein; ABC-3 protein; KEGG: ypp:YPDSF_0710 chelated iron transport system membrane protein YP_001872843.1 PFAM: aminoglycoside phosphotransferase; fructosamine kinase; KEGG: ypp:YPDSF_0708 hypothetical protein YP_001872845.1 KEGG: ypp:YPDSF_0707 yfeABCD locus regulator YP_001872846.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001872847.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: yps:YPTB2355 possible pectin degradation protein (sugar phosphate isomerase) YP_001872848.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_001872849.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_001872850.1 PFAM: periplasmic pectate lyase; KEGG: yps:YPTB2358 exopolygalacturonate lyase YP_001872851.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1691 oligogalacturonide ABC tansporter, permease protein YP_001872852.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1690 oligogalacturonide ABC tansporter, permease protein YP_001872853.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_1689 oligogalacturonide ABC transporter, ATP-binding protein YP_001872854.1 PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_1688 oligogalacturonide ABC transporter, periplasmic oligogalacturonide-binding protein YP_001872855.1 PFAM: Oligogalacturonate-specific porin; KEGG: ypi:YpsIP31758_1687 oligogalacturonate-specific porin protein KdgM YP_001872856.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: ypi:YpsIP31758_1686 putative metal-dependent hydrolase, membrane-bound YP_001872857.1 PFAM: sodium:dicarboxylate symporter; KEGG: yps:YPTB2365 DAACS family Na/dicarboxylate symporter YP_001872858.1 PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: ypi:YpsIP31758_1684 N-acetylmuramoyl-L-alanine amidase, family 2 YP_001872859.1 PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: ypp:YPDSF_1734 IclR-family transcriptional regulatory protein YP_001872860.1 PFAM: WD40 domain protein beta Propeller; KEGG: ypi:YpsIP31758_1682 oligogalacturonide lyase YP_001872861.1 PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB2369 MFS superfamily multidrug efflux transporter YP_001872862.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: yps:YPTB2370 putative chaperone protein YP_001872863.1 PFAM: Fimbrial protein; KEGG: ypp:YPDSF_1738 fimbrial protein YP_001872864.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: ypi:YpsIP31758_1677 fimbrial usher protein YP_001872865.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: yps:YPTB2373 putative chaperone protein YP_001872866.1 PFAM: Fimbrial protein; KEGG: ypp:YPDSF_1741 fimbrial protein YP_001872868.1 putative metalloprotease YP_001872869.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001872870.1 affects solute and DNA transport through an unknown mechanism YP_001872871.1 KEGG: ypi:YpsIP31758_1670 hypothetical protein YP_001872872.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: Paraquat-inducible protein A; KEGG: yps:YPTB2379 hypothetical protein YP_001872873.1 PFAM: Mammalian cell entry related domain protein; KEGG: ypp:YPDSF_1747 hypothetical protein YP_001872874.1 PFAM: Spore coat U domain protein; KEGG: ypi:YpsIP31758_1667 hypothetical protein YP_001872875.1 PFAM: Spore coat U domain protein; KEGG: ypm:YP_1724 hypothetical protein YP_001872876.1 PFAM: Spore coat U domain protein; KEGG: ypi:YpsIP31758_1665 hypothetical protein YP_001872877.1 KEGG: ypg:YpAngola_A2670 pilus assembly chaperone YP_001872878.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: yps:YPTB2385 probable outer membrane usher protein YP_001872879.1 PFAM: Spore coat U domain protein; KEGG: ypi:YpsIP31758_1661 spore coat U domain protein YP_001872880.1 PFAM: protein of unknown function DUF1480; KEGG: ypi:YpsIP31758_1660 hypothetical protein YP_001872881.1 PFAM: protein of unknown function DUF437; KEGG: ypp:YPDSF_1755 hypothetical protein YP_001872882.1 KEGG: ypi:YpsIP31758_1658 hypothetical protein YP_001872883.1 KEGG: ypi:YpsIP31758_1657 hypothetical protein YP_001872884.1 PFAM: Patatin; KEGG: ypp:YPDSF_1759 lipoprotein YP_001872885.1 KEGG: ypi:YpsIP31758_1654 hypothetical protein YP_001872887.1 KEGG: ypg:YpAngola_A3527 hypothetical protein YP_001872888.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001872890.1 KEGG: yps:YPTB2393 hypothetical protein YP_001872891.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: yps:YPTB2394 putative surface protein YP_001872892.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; KEGG: ypi:YpsIP31758_1649 N-acetylmuramoyl-L-alanine amidase, family 2 YP_001872893.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_001872894.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble YP_001872895.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001872896.1 methylates the MCP YP_001872897.1 PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ypp:YPDSF_1771 hypothetical protein YP_001872898.1 PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ypi:YpsIP31758_1642 methyl-accepting chemotaxis protein YP_001872899.1 KEGG: ypi:YpsIP31758_1641 putative lipoprotein YP_001872900.1 KEGG: ypi:YpsIP31758_1640 putative integral membrane protein YP_001872901.1 PFAM: CheW domain protein; KEGG: ypi:YpsIP31758_1639 chemotaxis protein CheW YP_001872902.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_001872903.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001872904.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001872905.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_001872906.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_001872907.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; magnesium-translocating P-type ATPase; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: yps:YPTB2410 Mg(2+) transport protein B, P-type ATPase YP_001872908.1 PFAM: MgtC/SapB transporter; KEGG: ypi:YpsIP31758_1632 putative transporter, Mg2+ transporter-C (MgtC) family YP_001872909.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: yps:YPTB2412 methyl-accepting chemotaxis protein III (MCP-III) (ribose and... YP_001872910.1 KEGG: ypp:YPDSF_1790 hypothetical protein YP_001872911.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ypp:YPDSF_1791 cold shock protein YP_001872912.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_001872914.1 TIGRFAM: NAD(P)H quinone oxidoreductase, PIG3 family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: yps:YPTB2416 probable zinc-binding dehydrogenase YP_001872916.1 KEGG: ypi:YpsIP31758_1627 hypothetical protein YP_001872918.1 PFAM: regulatory protein AsnC/Lrp family; KEGG: ypi:YpsIP31758_1625 transcriptional regulator, AsnC family YP_001872919.1 KEGG: yps:YPTB2419 hypothetical protein YP_001872920.1 KEGG: ypi:YpsIP31758_1623 hypothetical protein YP_001872921.1 PFAM: histidine acid phosphatase; KEGG: ypi:YpsIP31758_1622 periplasmic AppA protein YP_001872922.1 KEGG: ypp:YPDSF_1800 hypothetical protein YP_001872923.1 PFAM: helix-turn-helix HxlR type; KEGG: ypm:YP_1776 predicted transcriptional regulators YP_001872924.1 PFAM: 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; KEGG: yps:YPTB2423 hypothetical protein YP_001872925.1 KEGG: yps:YPTB2424 putative methyl-accepting chemotaxis protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein YP_001872926.1 KEGG: ypi:YpsIP31758_1617 hypothetical protein YP_001872927.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: yps:YPTB2426 sucrose operon repressor LacI-family YP_001872928.1 Converts isocitrate to alpha ketoglutarate YP_001872929.1 PFAM: pseudouridine synthase; KEGG: ypp:YPDSF_1808 pseudouridine synthase YP_001872930.1 PFAM: NUDIX hydrolase; KEGG: yps:YPTB2429 hypothetical protein YP_001872931.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001872932.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001872933.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001872934.1 KEGG: ypk:y1796 hypothetical protein YP_001872935.1 KEGG: ypp:YPDSF_1813 lipoprotein YP_001872936.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_001872937.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PhoQ Sensor domain protein; KEGG: ypn:YPN_1998 sensor protein kinase YP_001872938.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji jmjC domain protein; KEGG: ypp:YPDSF_1816 hypothetical protein YP_001872939.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001872940.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001872941.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_001872942.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001872943.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_001872944.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_001872945.1 KEGG: yps:YPTB2443 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001872946.1 PFAM: 17 kDa surface antigen; KEGG: ypm:YP_1753 hypothetical protein YP_001872947.1 KEGG: ypp:YPDSF_1827 hypothetical protein YP_001872948.1 KEGG: yps:YPTB2446 hypothetical protein YP_001872949.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ypp:YPDSF_1830 NADH dehydrogenase YP_001872950.1 PFAM: protein of unknown function UPF0227; KEGG: ypi:YpsIP31758_1593 hypothetical protein YP_001872951.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001872952.1 TIGRFAM: thiamine kinase; PFAM: Choline/ethanolamine kinase; aminoglycoside phosphotransferase; KEGG: ypp:YPDSF_1833 hypothetical protein YP_001872953.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: yps:YPTB2451 putative lipoprotein YP_001872954.1 PFAM: protein of unknown function DUF1425; KEGG: ypi:YpsIP31758_1589 putative lipoprotein YP_001872955.1 PFAM: histidine triad (HIT) protein; KEGG: ypp:YPDSF_1836 hypothetical protein YP_001872956.1 catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001872957.1 KEGG: yps:YPTB2456 hypothetical protein YP_001872958.1 KEGG: yps:YPTB2458 hypothetical protein YP_001872960.1 KEGG: yps:YPTB2459 hypothetical protein YP_001872962.1 KEGG: yps:YPTB2460 putative capsid portal protein YP_001872963.1 KEGG: yps:YPTB2461 hypothetical protein YP_001872964.1 KEGG: plu:plu1550 hypothetical protein YP_001872965.1 KEGG: yps:YPTB2462 hypothetical protein YP_001872968.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001872969.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: ypp:YPDSF_1840 deoxyribonuclease YP_001872970.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001872971.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001872972.1 PFAM: aminodeoxychorismate lyase; KEGG: yps:YPTB2467 hypothetical protein YP_001872973.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_001872974.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001872975.1 carries the fatty acid chain in fatty acid biosynthesis YP_001872976.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001872977.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: ypp:YPDSF_1849 malonyl CoA-acyl carrier protein transacylase YP_001872978.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001872979.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001872980.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001872981.1 PFAM: protein of unknown function DUF177; KEGG: ypi:YpsIP31758_1573 hypothetical protein YP_001872982.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001872983.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_001872985.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_001872986.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: ypi:YpsIP31758_1568 antibiotic biosynthesis monooxygenase domain protein YP_001872987.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001872988.1 PFAM: DinI family protein; KEGG: ypi:YpsIP31758_1566 DNA-damage-inducible protein I YP_001872989.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_001872990.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_001872991.1 KEGG: ypp:YPDSF_1864 LuxR-family regulatory protein YP_001872992.1 PFAM: transposase mutator type; KEGG: yps:YPTB3311 putative transposase YP_001872993.1 PFAM: regulatory protein LuxR; KEGG: ypp:YPDSF_1864 LuxR-family regulatory protein YP_001872994.1 KEGG: ypi:YpsIP31758_1562 hypothetical protein YP_001872995.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_001872996.1 PFAM: Rhodanese domain protein; KEGG: ypi:YpsIP31758_1560 rhodanese domain protein YP_001872997.1 KEGG: ypp:YPDSF_1867 hypothetical protein YP_001872998.1 KEGG: ypp:YPDSF_1868 membrane protein YP_001872999.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001873001.1 TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_1555 proton dependent peptide transporter YP_001873002.1 PFAM: protein of unknown function DUF1375; KEGG: yps:YPTB2492 predicted lipoprotein YP_001873003.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_001873004.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_001873005.1 KEGG: yen:YE1604 osmoregulated periplasmic glucan biosynthetic protein YP_001873006.1 KEGG: ypi:YpsIP31758_1550 hypothetical protein YP_001873007.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_001873008.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: yps:YPTB2498 possible DMT superfamliy, DME family drug/metabolite exporter YP_001873009.1 PFAM: autoinducer synthesis protein; KEGG: yps:YPTB2499 N-acylhomoserine lactone synthase YpeI YP_001873010.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein; KEGG: ypi:YpsIP31758_1547 transcriptional regulator, LuxR family YP_001873011.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB2501 putative LysR-family transcriptional regulator YP_001873012.1 KEGG: ypg:YpAngola_A1719 hypothetical protein YP_001873013.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_1874 transporter protein YP_001873014.1 TIGRFAM: formaldehyde-activating enzyme; PFAM: Formaldehyde-activating enzyme (Fae); KEGG: ypi:YpsIP31758_1542 hypothetical protein YP_001873015.1 PFAM: aldo/keto reductase; KEGG: yps:YPTB2504 putative oxidoreductase YP_001873016.1 TIGRFAM: CRISPR-associated protein, Csy4 family; PFAM: CRISPR-associated protein Csy4; KEGG: ypp:YPDSF_1877 hypothetical protein YP_001873017.1 TIGRFAM: CRISPR-associated protein, Csy3 family; PFAM: CRISPR-associated protein Csy3; KEGG: yps:YPTB2506 hypothetical protein YP_001873018.1 TIGRFAM: CRISPR-associated protein, Csy2 family; PFAM: CRISPR-associated protein Csy2; KEGG: yps:YPTB2507 hypothetical protein YP_001873019.1 TIGRFAM: CRISPR-associated protein, Csy1 family; PFAM: CRISPR-associated protein Csy1; KEGG: yps:YPTB2508 hypothetical protein YP_001873020.1 TIGRFAM: CRISPR-associated helicase Cas3 family; KEGG: yps:YPTB2509 hypothetical protein YP_001873021.1 TIGRFAM: CRISPR-associated protein Cas1; KEGG: yps:YPTB2510 hypothetical protein YP_001873022.1 PFAM: MscS Mechanosensitive ion channel; KEGG: yps:YPTB2511 putative mechanosensitive ion channel YP_001873023.1 KEGG: yps:YPTB2512 hypothetical protein YP_001873024.1 KEGG: yps:YPTB2513 hypothetical protein YP_001873025.1 PFAM: Protein of unknown function DUF1861; KEGG: yps:YPTB2514 hypothetical protein YP_001873026.1 PFAM: glycosidase PH1107-related; KEGG: ypi:YpsIP31758_1530 hypothetical protein YP_001873027.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1529 carbohydrate uptake (CUT1 family) ABC transporter, permease protein YP_001873028.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yps:YPTB2517 sugar ABC transporter, permease protein YP_001873029.1 PFAM: extracellular solute-binding protein family 1; KEGG: yps:YPTB2518 putative ABC type perplasmic sugar-binding protein YP_001873030.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: ypp:YPDSF_1891 LacI-family transcriptional regulatory protein YP_001873031.1 PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: ypp:YPDSF_1892 phosphomannomutase YP_001873032.1 PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_1524 carbohydrate uptake (CUT1 family) ABC transporter, ATP-binding protein YP_001873033.1 KEGG: ypi:YpsIP31758_1522 hypothetical protein YP_001873034.1 KEGG: ypi:YpsIP31758_1521 hypothetical protein YP_001873035.1 KEGG: yps:YPTB2527 putative hemolysin YP_001873036.1 KEGG: yps:YPTB2525 hypothetical protein YP_001873037.1 KEGG: yps:YPTB2526 hypothetical protein YP_001873038.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: yps:YPTB2527 putative hemolysin YP_001873039.1 PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: ypp:YPDSF_1903 hemolysin activator protein YP_001873040.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: yps:YPTB2529 putative dioxygenase beta subunit YP_001873041.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: ypi:YpsIP31758_1516 rieske 2Fe-2S domain protein YP_001873042.1 member of the betaine, carnitine, choline transporter (BCCT) family; unknown function YP_001873043.1 KEGG: ypi:YpsIP31758_1513 hypothetical protein YP_001873044.1 TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: ypp:YPDSF_1907 tartrate dehydrogenase YP_001873045.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB2533 putativeLlysR-family transcriptional regulatory protein YP_001873046.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_1510 sugar-binding transcriptional regulator, LacI family YP_001873047.1 PFAM: inner-membrane translocator; KEGG: ypp:YPDSF_1910 sugar transport system, permease protein YP_001873048.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB2536 putative ABC sugar (sorbitol) transporter, ATP-binding subunit YP_001873049.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: yps:YPTB2537 ABC transporter, periplasmic sugar (possibly sorbitol) binding protein YP_001873050.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ypp:YPDSF_1914 zinc-binding dehydrogenase YP_001873051.1 KEGG: ypi:YpsIP31758_1505 hypothetical protein YP_001873052.1 KEGG: ypi:YpsIP31758_1503 hypothetical protein YP_001873053.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: ypp:YPDSF_1917 membrane protein YP_001873054.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_001873055.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ypp:YPDSF_1919 membrane protein YP_001873056.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ypn:YPN_2103 hypothetical protein YP_001873057.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_001873058.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_001873059.1 PFAM: protein of unknown function DUF218; KEGG: ypp:YPDSF_1923 hypothetical protein YP_001873060.1 similar to periplasmic-binding component of ABC transporters YP_001873061.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_001873062.1 similar to ATP-binding component of ABC transporters YP_001873063.1 KEGG: yps:YPTB2551 putative chemotactic transducer; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001873064.1 PFAM: protein of unknown function DUF890; KEGG: ypm:YP_2331 putative SAM-dependent methyltransferase YP_001873065.1 PFAM: protein of unknown function DUF1471; KEGG: ypp:YPDSF_1930 hypothetical protein YP_001873066.1 PFAM: glycosyl transferase family 3; KEGG: yps:YPTB2555 hypothetical protein YP_001873067.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: yps:YPTB2556 O-succinylbenzoic acid--CoA ligase YP_001873068.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001873069.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001873070.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_001873071.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001873072.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: ypp:YPDSF_1938 menaquinone-specific isochorismate synthase YP_001873073.1 KEGG: ypp:YPDSF_1939 hypothetical protein YP_001873074.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: ypi:YpsIP31758_1479 hypothetical protein YP_001873075.1 KEGG: ypi:YpsIP31758_1477 hypothetical protein YP_001873076.1 KEGG: yps:YPTB2564 hypothetical protein YP_001873077.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001873078.1 PFAM: protein of unknown function DUF336; KEGG: yps:YPTB2566 hypothetical protein YP_001873079.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: yps:YPTB2567 putative 2-ketogluconate transporter, ACS family-MFS superfamily YP_001873080.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: yps:YPTB2568 putative D-isomer specific 2-hydroxyacid dehydrogenase family YP_001873081.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: yps:YPTB2569 putative LacI-family transcriptional regulatory protein YP_001873082.1 PFAM: protein of unknown function DUF187; KEGG: yps:YPTB2570 putative lipoprotein YP_001873083.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_001873084.1 TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; KEGG: yps:YPTB2572 putative thermosensitive gluconokinase YP_001873085.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_1468 hypothetical protein YP_001873086.1 KEGG: yps:YPTB2574 hypothetical protein YP_001873087.1 Catalyzes the transfer of electrons from NADH to quinone YP_001873088.1 Catalyzes the transfer of electrons from NADH to quinone YP_001873089.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001873090.1 Catalyzes the transfer of electrons from NADH to quinone YP_001873091.1 Catalyzes the transfer of electrons from NADH to quinone YP_001873092.1 Catalyzes the transfer of electrons from NADH to quinone YP_001873093.1 Catalyzes the transfer of electrons from NADH to quinone YP_001873094.1 Catalyzes the transfer of electrons from NADH to quinone YP_001873095.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_001873096.1 Catalyzes the transfer of electrons from NADH to quinone YP_001873097.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_001873098.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001873099.1 Catalyzes the transfer of electrons from NADH to quinone YP_001873100.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypm:YP_2367 LysR-family transcriptional regulatory protein YP_001873101.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001873102.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: ypi:YpsIP31758_1449 5'-nucleotidase YfbR YP_001873103.1 KEGG: yps:YPTB2591 hypothetical protein YP_001873104.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: ypg:YpAngola_A1821 citrate transporter family protein YP_001873105.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: yps:YPTB2593 putative phosphatase YP_001873106.1 PFAM: YfbU family protein; KEGG: ypi:YpsIP31758_1445 YfbU domain protein YP_001873107.1 PFAM: protein of unknown function DUF412; KEGG: ypi:YpsIP31758_1444 hypothetical protein YP_001873108.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001873109.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001873110.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_1441 sugar-binding transcriptional regulator, LacI family YP_001873111.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: ypi:YpsIP31758_1440 mannitol-specific cryptic phosphotransferase enzyme IIA component YP_001873112.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: ypp:YPDSF_1977 hypothetical protein YP_001873113.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_001873114.1 PFAM: NUDIX hydrolase; KEGG: ypp:YPDSF_1979 hypothetical protein YP_001873115.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: ypa:YPA_2062 hypothetical protein YP_001873116.1 PFAM: EAL domain protein; KEGG: yps:YPTB2605 hypothetical protein YP_001873117.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; domain of unknown function DUF1731; KEGG: ypp:YPDSF_1983 hypothetical protein YP_001873118.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB2607 histidine/lysine/arginine/ornithine transporter subunit YP_001873119.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1430 histidine ABC transporter, permease protein HisM YP_001873120.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1429 histidine ABC transporter, permease protein HisQ YP_001873121.1 TIGRFAM: cationic amino acid ABC transporter, periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; KEGG: ypi:YpsIP31758_1428 histidine ABC transporter, periplasmic histidine-binding protein YP_001873122.1 KEGG: bmv:BMASAVP1_0167 putative polyketide synthase PksJ YP_001873123.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_001873124.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001873125.1 membrane protein required for colicin V production YP_001873126.1 PFAM: Sporulation domain protein; KEGG: ypi:YpsIP31758_1424 sporulation and cell division repeat protein YP_001873127.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: ypi:YpsIP31758_1423 FolC bifunctional protein YP_001873128.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001873129.1 PFAM: SNARE associated Golgi protein; KEGG: ypp:YPDSF_1994 membrane protein YP_001873130.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001873131.1 PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; KEGG: ypp:YPDSF_1996 aspartate-semialdehyde dehydrogenase YP_001873132.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ypp:YPDSF_1997 D-isomer specific 2-hydroxyacid dehydrogenase YP_001873133.1 PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; KEGG: yps:YPTB2621 putative AraC-family regulatory protein YP_001873134.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: yps:YPTB2622 putative DMT superfamily drug/metabolite efflux protein YP_001873135.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_001873136.1 PFAM: Fimbrial protein; KEGG: ypi:YpsIP31758_1413 fimbria protein YP_001873137.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: ypp:YPDSF_2002 aspartate/glutamate racemase YP_001873138.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001873139.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_001873140.1 PFAM: YfcL protein; KEGG: ypi:YpsIP31758_1409 hypothetical protein YP_001873141.1 PFAM: protein of unknown function DUF462; KEGG: yps:YPTB2629 hypothetical protein YP_001873142.1 PFAM: protein of unknown function DUF81; KEGG: ypp:YPDSF_2007 membrane protein YP_001873143.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_001873144.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001873145.1 involved in methylation of ribosomal protein L3 YP_001873146.1 PFAM: Smr protein/MutS2; KEGG: yps:YPTB2634 hypothetical protein YP_001873147.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: ypp:YPDSF_2012 phosphohistidine phosphatase YP_001873148.1 KEGG: ypk:y1581 hypothetical protein YP_001873149.1 KEGG: ypi:YpsIP31758_1401 hypothetical protein YP_001873150.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_001873151.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001873152.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_1398 conserved hypothetical protein TIGR00743 YP_001873153.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: ypi:YpsIP31758_1397 long-chain fatty acid transport protein YP_001873154.1 PFAM: VacJ family lipoprotein; KEGG: ypp:YPDSF_2017 VacJ lipoprotein YP_001873155.1 TIGRFAM: cytochrome c-type biogenesis protein CcmI; PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: yps:YPTB2641 putative cytochrome c-type biogenesis protein YP_001873156.1 PFAM: cytochrome C biogenesis protein; KEGG: ypi:YpsIP31758_1394 putative cytochrome c-type biogenesis protein YP_001873157.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: ypp:YPDSF_2020 thiol:disulfide interchange protein DsbE YP_001873158.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: ypi:YpsIP31758_1392 cytochrome c-type biogenesis protein CcmF YP_001873159.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001873160.1 TIGRFAM: heme exporter protein CcmD; PFAM: Heme exporter protein D (CcmD); KEGG: yps:YPTB2646 putative heme exporter protein D YP_001873161.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: yps:YPTB2647 putative ABC type heme exporter, permease subunit CcmC YP_001873162.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: ypp:YPDSF_2025 heme exporter protein B YP_001873163.1 ATP-binding protein; required for proper cytochrome c maturation YP_001873164.1 KEGG: yps:YPTB2650 hypothetical protein YP_001873165.1 PFAM: LemA family protein; KEGG: yps:YPTB2651 hypothetical protein YP_001873166.1 KEGG: yps:YPTB2652 hypothetical protein YP_001873167.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: ypi:YpsIP31758_1380 alkylphosphonate utilization operon protein PhnA YP_001873168.1 KEGG: ypp:YPDSF_2031 membrane protein YP_001873169.1 TIGRFAM: type VI secretion system lysozyme-related protein; PFAM: GPW/gp25 family protein; KEGG: ypi:YpsIP31758_1378 hypothetical protein YP_001873170.1 PFAM: virulence protein SciE type; KEGG: yps:YPTB2656 hypothetical protein YP_001873171.1 KEGG: yps:YPTB2657 hypothetical protein YP_001873172.1 KEGG: ypp:YPDSF_2035 hypothetical protein YP_001873173.1 TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: ypi:YpsIP31758_1374 rhs element Vgr protein YP_001873174.1 TIGRFAM: type VI secretion protein IcmF; PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: ypi:YpsIP31758_1373 hypothetical protein YP_001873175.1 TIGRFAM: type IV / VI secretion system protein, DotU family; type VI secretion system OmpA/MotB family protein; PFAM: OmpA/MotB domain protein; KEGG: yps:YPTB2661 possible OmpA/MotB family protein YP_001873176.1 TIGRFAM: type VI secretion protein, VC_A0114 family; PFAM: protein of unknown function DUF876; KEGG: ypi:YpsIP31758_1371 hypothetical protein YP_001873177.1 KEGG: yps:YPTB2663 hypothetical protein YP_001873178.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: yps:YPTB2664 hypothetical protein YP_001873179.1 TIGRFAM: type VI secretion protein, EvpB/VC_A0108 family; PFAM: protein of unknown function DUF877; KEGG: ypi:YpsIP31758_1368 hypothetical protein YP_001873180.1 TIGRFAM: type VI secretion protein, VC_A0107 family; PFAM: conserved hypothetical protein; KEGG: ypp:YPDSF_2047 hypothetical protein YP_001873181.1 PFAM: Fimbrial protein; KEGG: ypi:YpsIP31758_1366 fimbrial protein YP_001873182.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: yps:YPTB2668 putative outer membrane fimbrial usher porin YP_001873183.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: ypp:YPDSF_2052 pili chaperone protein YP_001873184.1 PFAM: Fimbrial protein; KEGG: yps:YPTB2670 frimbrial protein YP_001873185.1 KEGG: yps:YPTB2671 Clp ATPase; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001873186.1 TIGRFAM: type VI secretion protein, VC_A0110 family; PFAM: protein of unknown function DUF879; KEGG: ypi:YpsIP31758_1361 hypothetical protein YP_001873187.1 TIGRFAM: type VI secretion protein, VC_A0111 family; PFAM: protein of unknown function DUF1305; KEGG: ypi:YpsIP31758_1360 hypothetical protein YP_001873188.1 PFAM: ImpA domain protein; KEGG: ypi:YpsIP31758_1359 ImpA domain protein YP_001873189.1 KEGG: ypi:YpsIP31758_1358 hypothetical protein YP_001873190.1 KEGG: yps:YPTB2676 hypothetical protein YP_001873191.1 PFAM: OmpA/MotB domain protein; KEGG: yps:YPTB2678 putative OmpA family outer membrane porin YP_001873192.1 PFAM: Domain of unknown function DUF1795; KEGG: ypi:YpsIP31758_1354 hypothetical protein YP_001873193.1 PFAM: regulatory protein LuxR; KEGG: ypi:YpsIP31758_1353 transcriptional regulator, LuxR family YP_001873194.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_001873195.1 PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_1350 iron(III) ABC transporter, permease protein, periplasmic iron(III)-binding protein YP_001873196.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1349 iron(III) ABC transporter, permease protein YP_001873197.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_1348 iron(III) ABC transporter, ATP-binding protein YP_001873198.1 KEGG: yps:YPTB2685 hypothetical protein YP_001873199.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: ypi:YpsIP31758_1346 hypothetical protein YP_001873201.1 KEGG: yps:YPTB2687 hypothetical protein YP_001873202.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: ypi:YpsIP31758_1344 putative anaerobic dimethyl sulfoxide reductase, A subunit YP_001873203.1 TIGRFAM: dimethylsulfoxide reductase, chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ypi:YpsIP31758_1343 putative anaerobic dimethyl sulfoxide reductase, B subunit YP_001873204.1 KEGG: yps:YPTB2690 putative dimethyl sulfoxide reductase chain C protein YP_001873205.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: yps:YPTB2691 hypothetical protein YP_001873206.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ypi:YpsIP31758_1340 putative ferredoxin-type protein NapF YP_001873207.1 PFAM: protein of unknown function DUF799; KEGG: ypp:YPDSF_2077 lipoprotein YP_001873208.1 KEGG: ypi:YpsIP31758_1338 putative lipoprotein YP_001873209.1 PFAM: Curli production assembly/transport component CsgG; KEGG: yps:YPTB2695 putative lipoprotein YP_001873210.1 KEGG: yps:YPTB2696 hypothetical protein YP_001873211.1 PFAM: cytochrome B561; KEGG: ypp:YPDSF_2081 B-type cytochrome YP_001873212.1 PFAM: aminotransferase class I and II; KEGG: ypm:YP_2600 aminotransferase YP_001873213.1 PFAM: protein of unknown function DUF1479; KEGG: ypp:YPDSF_2083 hypothetical protein YP_001873214.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001873215.1 PFAM: transmembrane pair domain protein; KEGG: yps:YPTB2701 hypothetical protein YP_001873216.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypp:YPDSF_2086 LysR-family transcriptional regulatory protein YP_001873217.1 PFAM: aldo/keto reductase; KEGG: ypi:YpsIP31758_1329 oxidoreductase, aldo/keto reductase family YP_001873218.1 KEGG: ypi:YpsIP31758_1328 hypothetical protein YP_001873219.1 TIGRFAM: Mn2+/Fe2+ transporter, NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: ypp:YPDSF_2089 manganese transport protein MntH YP_001873220.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: ypn:YPN_1399 nucleoside permease YP_001873221.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001873222.1 PFAM: protein of unknown function DUF925; KEGG: ypp:YPDSF_2094 hypothetical protein YP_001873223.1 KEGG: ypi:YpsIP31758_1323 hypothetical protein YP_001873224.1 KEGG: ypp:YPDSF_2096 hypothetical protein YP_001873225.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_001873226.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_001873227.1 putative role in sulfur assimilation YP_001873228.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_001873229.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: ypi:YpsIP31758_1317 phosphocarrier, HPr family YP_001873230.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system YP_001873231.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001873232.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ypi:YpsIP31758_1314 sensor histidine kinase CpxA YP_001873233.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ypp:YPDSF_2106 two-component system response regulator YP_001873234.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: ypp:YPDSF_2107 HlyD family secretion protein YP_001873235.1 PFAM: ABC transporter related; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_1311 efflux ABC transporter, ATP-binding/permease protein YP_001873236.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: ypp:YPDSF_2109 pyridine nucleotide-disulphide oxidoreductase YP_001873237.1 PFAM: Na+/solute symporter; KEGG: ypi:YpsIP31758_1309 transporter, solute:sodium symporter (SSS) family YP_001873238.1 KEGG: ypm:YP_2628 hypothetical protein YP_001873239.1 PFAM: peptidase M24; KEGG: ypi:YpsIP31758_1308 peptidase, M24 family YP_001873240.1 PFAM: aminotransferase class I and II; KEGG: yps:YPTB2726 putative aminotransferase YP_001873241.1 PFAM: von Willebrand factor type A; KEGG: ypm:YP_2631 hypothetical protein YP_001873242.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ypi:YpsIP31758_1305 sensor histidine kinase YP_001873243.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ypp:YPDSF_2116 two-component response regulator YP_001873244.1 KEGG: ypg:YpAngola_A2764 hypothetical protein YP_001873245.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_001873246.1 KEGG: ypi:YpsIP31758_1302 sulfate/thiosulfate ABC transporter, ATP-binding protein CysA; TIGRFAM: sulfate ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase YP_001873247.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_001873248.1 TIGRFAM: sulfate ABC transporter, inner membrane subunit; sulfate ABC transporter, inner membrane subunit CysT; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_1300 sulfate/thiosulfate ABC transporter, permease protein CysT YP_001873249.1 TIGRFAM: sulfate ABC transporter, periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: yps:YPTB2735 thiosulfate transporter subunit YP_001873250.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_1298 transporter, major facilitator family YP_001873251.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: ypi:YpsIP31758_1297 transcriptional regulator, RpiR family YP_001873252.1 PFAM: conserved hypothetical protein; KEGG: ypg:YpAngola_A2772 hypothetical protein YP_001873253.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein YP_001873254.1 SMART: leucine-rich repeat-containing protein typical subtype; KEGG: yps:YPTB2740 putative antigenic leucine-rich repeat protein YP_001873256.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_001873257.1 PFAM: dihydrodipicolinate synthetase; KEGG: ypp:YPDSF_2129 N-acetylneuraminate lyase YP_001873258.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: yps:YPTB2743 hypothetical protein YP_001873259.1 PFAM: protein of unknown function DUF1131; KEGG: ypn:YPN_1359 lipoprotein YP_001873260.1 PFAM: nucleic acid binding OB-fold tRNA/helicase-type; conserved hypothetical protein; KEGG: ypi:YpsIP31758_1289 OB-fold nucleic acid binding domain protein YP_001873261.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: ypi:YpsIP31758_1288 putative autotransporter protein YP_001873262.1 KEGG: ypi:YpsIP31758_1287 hypothetical protein YP_001873263.1 KEGG: yen:YE1169 putative acetyltransferase YP_001873264.1 KEGG: ypi:YpsIP31758_1285 hypothetical protein YP_001873265.1 KEGG: yps:YPTB2750 hypothetical protein YP_001873266.1 KEGG: ypi:YpsIP31758_1283 hypothetical protein YP_001873267.1 KEGG: son:SO_4578 transposase, putative YP_001873268.1 KEGG: sbo:SBO_P120 IS630 ORF YP_001873269.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ypp:YPDSF_2136 acetyltransferase YP_001873270.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001873271.1 PFAM: protein of unknown function DUF188; KEGG: ypp:YPDSF_2138 hypothetical protein YP_001873272.1 KEGG: ypi:YpsIP31758_1278 hypothetical protein YP_001873273.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001873274.1 PFAM: NUDIX hydrolase; KEGG: ypi:YpsIP31758_1276 hydrolase, NUDIX family YP_001873276.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_001873277.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_001873278.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001873279.1 PFAM: NapD family protein; KEGG: ypn:YPN_1346 hypothetical protein YP_001873280.1 TIGRFAM: ferredoxin-type protein NapF; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ypi:YpsIP31758_1271 ferredoxin-type protein NapF YP_001873281.1 PFAM: regulatory protein LuxR; response regulator receiver; Bacterio-opsin activator HTH domain protein; KEGG: yps:YPTB2763 nitrate/nitrite response regulator protein NarP YP_001873282.1 KEGG: ypp:YPDSF_2147 hypothetical protein YP_001873283.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: ypi:YpsIP31758_1268 acriflavine resistance protein D YP_001873284.1 KEGG: ypi:YpsIP31758_1267 hypothetical protein YP_001873285.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: ypi:YpsIP31758_1266 putative metal-dependent hydrolase, membrane-bound YP_001873286.1 PFAM: Radical SAM domain protein; KEGG: yps:YPTB2768 putative sulfatase modifier protein YP_001873287.1 PFAM: sulfatase; KEGG: yps:YPTB2769 putative sulfatase YP_001873288.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB2770 probable ABC transporter, ATP-binding subunit YP_001873289.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_2154 binding protein-dependent transport system, inner-membrane component YP_001873290.1 PFAM: extracellular solute-binding protein family 1; KEGG: ypm:YP_2672 putative solute-binding periplasmic protein of ABC transporter YP_001873291.1 KEGG: ypi:YpsIP31758_1257 tetratricopeptide repeat protein YP_001873292.1 PFAM: arsenate reductase and related; KEGG: ypi:YpsIP31758_1256 hypothetical protein YP_001873293.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001873294.1 PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: ypp:YPDSF_2159 carboxypeptidase YP_001873295.1 KEGG: ypi:YpsIP31758_1253 hypothetical protein YP_001873297.1 PFAM: GCN5-related N-acetyltransferase; protein of unknown function DUF699 ATPase putative; KEGG: yps:YPTB2778 putative acetyltransferase YP_001873298.1 PFAM: protein of unknown function DUF441; KEGG: ypp:YPDSF_2162 membrane protein YP_001873299.1 PFAM: protein of unknown function zinc metallopeptidase putative; KEGG: ypi:YpsIP31758_1250 metalloprotease-like protein YP_001873301.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001873302.1 PFAM: NlpBDapX family lipoprotein; KEGG: ypi:YpsIP31758_1248 NlpB/DapX family lipoprotein YP_001873303.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001873304.1 negative transcriptional regulator of the gcvTHP operon YP_001873305.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_001873306.1 KEGG: yps:YPTB2786 hypothetical protein YP_001873307.1 KEGG: ypp:YPDSF_2170 hypothetical protein YP_001873308.1 PFAM: protein of unknown function UPF0118; KEGG: ypp:YPDSF_2172 membrane protein YP_001873309.1 PFAM: peptidase M48 Ste24p; KEGG: ypm:YP_2691 hypothetical protein YP_001873310.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: ypi:YpsIP31758_1238 arsenate reductase (glutaredoxin) YP_001873311.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001873312.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: ypi:YpsIP31758_1236 uracil permease YP_001873313.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001873314.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001873315.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001873316.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ypi:YpsIP31758_1232 spermidine N(1)-acetyltransferase YP_001873317.1 PFAM: protein of unknown function UPF0153; KEGG: ypi:YpsIP31758_1231 FliB family protein YP_001873318.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001873319.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypn:YPN_1304 phosphate transport system permease YP_001873320.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_2185 phosphate transport system permease YP_001873321.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001873322.1 PFAM: Ppx/GppA phosphatase; KEGG: ypp:YPDSF_2187 exopolyphosphatase YP_001873323.1 KEGG: ypi:YpsIP31758_1225 hypothetical protein YP_001873324.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: ypp:YPDSF_2189 divalent cation transport protein YP_001873325.1 KEGG: ypi:YpsIP31758_1223 putative chaperone protein YP_001873326.1 KEGG: ypi:YpsIP31758_1222 hypothetical protein YP_001873327.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_2191 ABC transporter permease YP_001873328.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yps:YPTB2808 putative ABC opine/polyamine transporter, permease subunit YP_001873329.1 PFAM: extracellular solute-binding protein family 1; KEGG: yps:YPTB2809 putative ABC opine/polyamine transporter, periplasmic binding protein YP_001873330.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_001873331.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: yps:YPTB2811 putative GntR-family regulatory protein and aminotransferase (MocR family) YP_001873332.1 KEGG: ypi:YpsIP31758_1216 spermidine/putrescine ABC transporter, ATP-binding subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase YP_001873333.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001873334.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_001873335.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_001873336.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_2201 membrane protein YP_001873337.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yps:YPTB2817 signal transduction histidine-protein kinase BaeS YP_001873338.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_001873339.1 PFAM: protein of unknown function DUF1508; KEGG: ypi:YpsIP31758_1209 hypothetical protein YP_001873340.1 PFAM: peptidase U32; KEGG: yps:YPTB2820 putative protease YP_001873341.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_001873342.1 PFAM: Inhibitor of vertebrate lysozyme; KEGG: yps:YPTB2822 hypothetical protein YP_001873343.1 KEGG: yps:YPTB2823 hypothetical protein YP_001873344.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_001873346.1 PFAM: protein of unknown function DUF943; KEGG: yps:YPTB2825 hypothetical protein YP_001873347.1 KEGG: yps:YPTB2826 hypothetical protein YP_001873348.1 PFAM: protein of unknown function DUF1240; KEGG: yps:YPTB2827 hypothetical protein YP_001873349.1 PFAM: protein of unknown function DUF1240; KEGG: yps:YPTB2828 hypothetical protein YP_001873350.1 PFAM: protein of unknown function DUF1240; KEGG: yps:YPTB2829 hypothetical protein YP_001873352.1 KEGG: yps:YPTB2830 hypothetical protein YP_001873353.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: ypi:YpsIP31758_1198 hypothetical protein YP_001873354.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001873355.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001873356.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001873357.1 KEGG: ypk:y1360 hypothetical protein YP_001873358.1 PFAM: protein of unknown function DUF1407; KEGG: ypi:YpsIP31758_1192 hypothetical protein YP_001873359.1 PFAM: Auxin Efflux Carrier; KEGG: yps:YPTB2836 possible AEC family malate permease YP_001873360.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001873361.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001873362.1 KEGG: ypp:YPDSF_2222 membrane protein YP_001873363.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001873364.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001873365.1 SMART: helix-turn-helix domain protein; KEGG: yps:YPTB2842 hypothetical protein YP_001873366.1 KEGG: ypi:YpsIP31758_1184 type IV pilus biogenesis/stability protein PilW; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001873367.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001873368.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001873369.1 SMART: beta and gamma crystallin; KEGG: ypp:YPDSF_2229 hypothetical protein YP_001873370.1 KEGG: ypi:YpsIP31758_1179 putative autotransporter protein YP_001873371.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: ypi:YpsIP31758_1179 putative autotransporter protein YP_001873372.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: ypi:YpsIP31758_1177 putative autotransporter protein YP_001873373.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_001873374.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001873375.1 TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528; KEGG: ypp:YPDSF_2235 hypothetical protein YP_001873376.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: ypp:YPDSF_2236 adrenodoxin family ferredoxin YP_001873377.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001873378.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001873379.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_001873380.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: yps:YPTB2858 scaffold protein YP_001873381.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001873382.1 regulates the expression of the iscRSUA operon YP_001873383.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: ypp:YPDSF_2243 SpoU-family rRNA methylase YP_001873384.1 PFAM: inositol monophosphatase; KEGG: ypp:YPDSF_2244 inositol monophosphatase family protein YP_001873385.1 PFAM: high-affinity nickel-transporter; KEGG: ypp:YPDSF_2245 membrane protein YP_001873386.1 PFAM: protein of unknown function DUF1007; KEGG: ypi:YpsIP31758_1163 hypothetical protein YP_001873387.1 PFAM: PRD domain protein; KEGG: ypi:YpsIP31758_1161 stationary phase inducible protein CsiE YP_001873388.1 putative transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_001873389.1 PFAM: virulence-related outer membrane protein; KEGG: ypa:YPA_2345 attachment invasion locus protein YP_001873391.1 KEGG: ypi:YpsIP31758_1159 hypothetical protein YP_001873392.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001873393.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_001873394.1 KEGG: ypp:YPDSF_2255 hypothetical protein YP_001873395.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_001873396.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001873397.1 KEGG: ypi:YpsIP31758_1153 hypothetical protein YP_001873398.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: ypp:YPDSF_2258 two-component system response regulator YP_001873399.1 KEGG: ypp:YPDSF_2259 lipoprotein YP_001873400.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: yps:YPTB2876 two-component system sensor kinase YP_001873401.1 KEGG: ypa:YPA_2357 hypothetical protein YP_001873402.1 KEGG: ypi:YpsIP31758_1149 hypothetical protein YP_001873403.1 KEGG: yps:YPTB2878 hypothetical protein YP_001873404.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001873405.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001873406.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: yps:YPTB2881 tRNA-specific adenosine deaminase YP_001873407.1 TIGRFAM: HAD superfamily (subfamily IF) hydrolase, YfhB; KEGG: ypg:YpAngola_A3620 HAD hydrolase YfhB YP_001873408.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_001873409.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: ypi:YpsIP31758_1142 transcriptional regulator, RpiR family YP_001873410.1 KEGG: ypi:YpsIP31758_1141 iron-sulfur cluster-binding protein YP_001873411.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001873412.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001873413.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001873414.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001873415.2 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001873416.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_001873417.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001873418.1 KEGG: ypi:YpsIP31758_1133 hypothetical protein YP_001873419.1 involved in the reduction of the SoxR iron-sulfur cluster YP_001873420.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_001873421.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: ypp:YPDSF_1559 sigma E factor negative regulatory protein YP_001873422.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001873423.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001873424.1 PFAM: methyltransferase small; Methyltransferase type 12; KEGG: ypm:YP_2513 SAM-dependent methyltransferase YP_001873425.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001873426.1 KEGG: ypg:YpAngola_A3600 hypothetical protein YP_001873427.1 PFAM: Ankyrin; KEGG: yps:YPTB2901 putative phospholipase A accessory protein YP_001873428.1 KEGG: ypg:YpAngola_A3598 hypothetical protein YP_001873429.1 KEGG: yps:YPTB2902 phospholipase A YP_001873430.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_001873431.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001873432.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline YP_001873433.1 PFAM: protein of unknown function DUF979; KEGG: ypi:YpsIP31758_1119 hypothetical protein YP_001873434.1 PFAM: protein of unknown function DUF969; KEGG: ypi:YpsIP31758_1118 hypothetical protein YP_001873435.1 PFAM: LamB/YcsF family protein; KEGG: ypm:YP_2504 hypothetical protein YP_001873436.1 TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: ypp:YPDSF_1572 hypothetical protein YP_001873437.1 PFAM: Allophanate hydrolase subunit 1; KEGG: ypi:YpsIP31758_1115 conserved hypothetical protein TIGR00370 YP_001873439.1 PFAM: protein of unknown function DUF34; KEGG: ypi:YpsIP31758_1114 conserved hypothetical protein TIGR00486 YP_001873440.1 PFAM: cyclic-AMP phosphodiesterase class-II; KEGG: ypp:YPDSF_1575 3',5'-cyclic-nucleotide phosphodiesterase YP_001873441.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_001873442.1 PFAM: Protein of unknown function DUF1722; KEGG: yps:YPTB2914 hypothetical protein YP_001873443.1 KEGG: ypi:YpsIP31758_1110 hypothetical protein YP_001873444.1 KEGG: ypp:YPDSF_1578 membrane protein YP_001873445.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001873446.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001873447.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_001873448.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_001873449.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_001873450.1 PFAM: protein of unknown function DUF6 transmembrane; Protein of unknown function DUF250; KEGG: ypp:YPDSF_1586 membrane protein YP_001873451.1 KEGG: ypi:YpsIP31758_1100 hypothetical protein YP_001873452.1 KEGG: ypg:YpAngola_A3575 hypothetical protein YP_001873453.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001873454.1 negative modulator of the initiation of chromosome replication YP_001873455.1 KEGG: ypp:YPDSF_1591 hypothetical protein YP_001873456.1 KEGG: ypm:YP_2485 hypothetical protein YP_001873457.1 PFAM: YdjC family protein; KEGG: ypp:YPDSF_1592 hypothetical protein YP_001873458.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_001873459.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001873460.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001873461.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_001873462.1 TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein; KEGG: yps:YPTB2932 camphor resistance protein CrcB YP_001873463.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001873464.1 PFAM: TrkA-N domain protein; Ion transport 2 domain protein; KEGG: ypi:YpsIP31758_1087 potassium channel protein Kch YP_001873465.1 KEGG: ypi:YpsIP31758_1086 hypothetical protein YP_001873466.1 TIGRFAM: high-affinity nickel-transporter; KEGG: ypi:YpsIP31758_1085 high-affinity nickel transport protein YP_001873467.1 TIGRFAM: urea transporter; PFAM: Urea transporter; KEGG: yps:YPTB2937 putative UreA transporter YP_001873468.1 PFAM: Urease accessory protein UreD; KEGG: ypi:YpsIP31758_1083 urease accessory protein UreD YP_001873469.1 TIGRFAM: urease accessory protein UreG; PFAM: cobalamin synthesis protein P47K; KEGG: ypp:YPDSF_1606 urease accessory protein YP_001873470.1 PFAM: Urease accessory protein UreF; KEGG: yps:YPTB2940 urease accessory protein YP_001873471.1 involved in the assembly of the urease metallocenter; possible nickel donor YP_001873472.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001873473.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta) YP_001873474.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_001873475.1 KEGG: ypg:YpAngola_A3552 hypothetical protein YP_001873476.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_1075 nickel ABC transporter, ATP-binding protein YP_001873477.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB2946 ABC nickel/di-oligopepetide transporter, ATP binding subunit YP_001873478.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_1614 binding-protein-dependent transport protein YP_001873479.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_1615 membrane protein YP_001873480.1 PFAM: extracellular solute-binding protein family 5; KEGG: yps:YPTB2949 ABC transporter, periplasmic nickel/di-oligopepetide binding protein YP_001873481.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: yen:YE0940 cold shock-like protein CspG YP_001873482.1 KEGG: ypi:YpsIP31758_1069 hypothetical protein YP_001873483.1 PFAM: protein of unknown function DUF1198; KEGG: ypp:YPDSF_1619 membrane protein YP_001873484.1 KEGG: ypi:YpsIP31758_1067 hypothetical protein YP_001873485.1 required for growth and survival under moderately acid conditions YP_001873486.1 TIGRFAM: glutaredoxin-like protein NrdH; PFAM: glutaredoxin; KEGG: ypi:YpsIP31758_1065 glutaredoxin-related protein NrdH YP_001873487.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_001873488.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001873489.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_001873490.1 KEGG: ypi:YpsIP31758_1061 glycine betaine/L-proline ABC transporter, ATP-binding protein; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: CBS domain containing protein; ABC transporter related; SMART: AAA ATPase YP_001873491.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_001873492.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine YP_001873493.1 KEGG: ypp:YPDSF_1425 hypothetical protein YP_001873494.1 TIGRFAM: urate catabolism protein; PFAM: polysaccharide deacetylase; KEGG: ypp:YPDSF_1628 hypothetical protein YP_001873495.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: yps:YPTB2963 putative nucleobase:cation symporter, NCS1 family YP_001873496.1 3'-5' exonuclease of DNA polymerase III YP_001873497.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001873498.1 PFAM: Methyltransferase type 11; KEGG: ypp:YPDSF_1632 hypothetical protein YP_001873499.1 TIGRFAM: hydroxyacylglutathione hydrolase; PFAM: beta-lactamase domain protein; KEGG: ypi:YpsIP31758_1052 metallo-beta-lactamase family protein YP_001873500.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_001873501.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ypp:YPDSF_1635 hypothetical protein YP_001873502.1 KEGG: ypn:YPN_2922 hypothetical protein YP_001873503.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_001873504.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001873505.1 part of the metNIQ transport system for methionine YP_001873506.1 part of the MetNIQ methionine uptake system YP_001873507.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: yps:YPTB2975 DL-methionine transporter substrate-binding subunit YP_001873508.1 KEGG: ypi:YpsIP31758_1040 putative lipoprotein YP_001873509.1 PFAM: protein of unknown function UPF0066; KEGG: ypp:YPDSF_1642 hypothetical protein YP_001873510.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001873511.1 PFAM: copper resistance lipoprotein NlpE; KEGG: ypm:YP_2782 lipoprotein involved with copper homeostasis and adhesion YP_001873512.1 PFAM: Class I peptide chain release factor; KEGG: ypp:YPDSF_1645 hypothetical protein YP_001873513.1 PFAM: YaeQ family protein; KEGG: ypi:YpsIP31758_1035 hypothetical protein YP_001873514.1 PFAM: protein of unknown function UPF0253; KEGG: ypi:YpsIP31758_1034 hypothetical protein YP_001873515.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_001873516.1 PFAM: cytochrome c class I; KEGG: ypi:YpsIP31758_1032 cytochrome c family protein YP_001873517.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_001873518.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: ypi:YpsIP31758_1030 glyoxalase family protein YP_001873519.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001873520.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001873521.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001873522.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001873523.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001873524.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001873525.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001873526.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: yps:YPTB2994 periplasmic chaperone YP_001873527.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_001873528.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_001873529.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_001873530.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_001873531.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001873532.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001873533.1 Catalyzes the phosphorylation of UMP to UDP YP_001873534.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001873535.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001873536.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001873537.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001873538.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001873539.1 KEGG: ypi:YpsIP31758_1009 hypothetical protein YP_001873540.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001873541.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_001873542.1 PFAM: protein of unknown function DUF446; KEGG: ypi:YpsIP31758_1006 hypothetical protein YP_001873544.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001873545.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001873546.1 PFAM: conserved hypothetical protein; KEGG: yps:YPTB3013 hypothetical protein YP_001873547.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_001873548.1 KEGG: ypp:YPDSF_1682 hypothetical protein YP_001873549.1 PFAM: protein of unknown function DUF423; KEGG: ypi:YpsIP31758_1000 hypothetical protein YP_001873550.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001873551.1 KEGG: cko:CKO_04173 hypothetical protein YP_001873552.1 TIGRFAM: cysteine desulfurase, catalytic subunit CsdA; PFAM: aminotransferase class V; KEGG: ypi:YpsIP31758_0998 cysteine sulfinate desulfinase YP_001873553.1 TIGRFAM: cysteine desulfurase, sulfur acceptor subunit CsdE; PFAM: Fe-S metabolism associated SufE; KEGG: ypi:YpsIP31758_0997 Fe-S metabolism associated protein YP_001873554.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: yps:YPTB3020 hypothetical protein YP_001873555.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001873556.1 PFAM: cell wall hydrolase/autolysin; KEGG: ypi:YpsIP31758_0994 N-acetylmuramoyl-L-alanine amidase, family 3 YP_001873557.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001873558.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001873559.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_001873560.1 PFAM: peptidase M16 domain protein; KEGG: ypi:YpsIP31758_0990 protease III YP_001873561.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_001873562.1 KEGG: ypi:YpsIP31758_0988 prepilin peptidase dependent protein-like protein YP_001873563.1 KEGG: ypp:YPDSF_1699 membrane protein YP_001873564.1 KEGG: ypp:YPDSF_1700 prepilin peptidase dependent protein YP_001873565.1 KEGG: ypi:YpsIP31758_0985 prepilin-type N-terminal cleavage/methylation domain protein YP_001873566.1 KEGG: ypm:YP_2876 hypothetical protein YP_001873567.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001873568.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001873569.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_001873570.1 hydrolyzes diadenosine polyphosphate YP_001873571.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001873572.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_001873573.1 KEGG: ypi:YpsIP31758_0978 hypothetical protein YP_001873574.1 KEGG: ypi:YpsIP31758_0977 hypothetical protein YP_001873575.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_0976 transporter, major facilitator family YP_001873576.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_001873577.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: yps:YPTB3043 putative biotin sulfoxide reductas2 YP_001873578.1 controls transcription of galETKM YP_001873579.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_001873580.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_001873581.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_0971 transporter, major facilitator family YP_001873582.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB3048 LysR-family transcriptional regulatory protein YP_001873583.1 PFAM: beta-lactamase domain protein; KEGG: yps:YPTB3049 hypothetical protein YP_001873584.1 KEGG: yps:YPTB3050 hypothetical protein YP_001873585.1 PFAM: ligand binding Tar domain protein; histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ypp:YPDSF_1719 methyl-accepting chemotaxis protein YP_001873586.1 KEGG: yps:YPTB3052 hypothetical protein YP_001873587.1 PFAM: transcriptional regulator domain protein; KEGG: yps:YPTB3053 putative regulatory membrane protein YP_001873588.1 KEGG: yps:YPTB3054 hypothetical protein YP_001873589.1 PFAM: peptidase A24A prepilin type IV; peptidase A24A domain protein; KEGG: yps:YPTB3055 prepilin peptidase YP_001873590.1 KEGG: yps:YPTB3056 hypothetical protein YP_001873591.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: yps:YPTB3057 general secretion pathway protein L YP_001873592.1 KEGG: yps:YPTB3058 general secretion pathway protein K YP_001873593.1 TIGRFAM: general secretion pathway protein J; KEGG: yps:YPTB3059 putative general secretion pathway protein J YP_001873594.1 PFAM: type II secretion system protein I/J; KEGG: yps:YPTB3060 general secretion pathway protein I YP_001873595.1 KEGG: yps:YPTB3061 general secretion pathway protein H YP_001873596.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: ypi:YpsIP31758_0956 general secretion pathway protein G YP_001873597.1 PFAM: type II secretion system protein; KEGG: ypm:YP_2842 putative general protein secretion protein YP_001873598.1 PFAM: type II secretion system protein E; SMART: AAA ATPase; KEGG: ypm:YP_2841 general secretion pathway protein E YP_001873599.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: yps:YPTB3065 general secretion pathway protein D YP_001873600.1 KEGG: yps:YPTB3066 general secretion pathway protein C YP_001873601.1 KEGG: ypi:YpsIP31758_0951 hypothetical protein YP_001873602.1 PFAM: carbonic anhydrase; KEGG: yps:YPTB3068 putative carbonic anhydrase YP_001873603.1 KEGG: ypi:YpsIP31758_0949 hypothetical protein YP_001873604.1 KEGG: ypi:YpsIP31758_0948 hypothetical protein YP_001873605.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; KEGG: ypn:YPN_3026 hypothetical protein YP_001873606.1 PFAM: polysaccharide lyase family 8; Lyase ; Lyase catalytic; KEGG: yps:YPTB3073 possible chondroitin ABC lyase YP_001873607.1 PFAM: sulfatase; KEGG: yps:YPTB3074 putative sulfatase YP_001873608.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: ypp:YPDSF_0683 DeoR-family regulatory protein YP_001873609.1 TIGRFAM: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: yps:YPTB3076 putative tagatose 6-phosphate kinase YP_001873610.1 TIGRFAM: sugar isomerase, AgaS family; PFAM: sugar isomerase (SIS); KEGG: ypi:YpsIP31758_0941 putative tagatose-6-phosphate ketose/aldose isomerase AgaS YP_001873611.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB subunit; PFAM: PTS system sorbose subfamily IIB component; KEGG: ypi:YpsIP31758_0940 PTS system, N-acetylgalactosamine-specific phosphotransferase enzyme IIB component2 YP_001873612.1 PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: ypp:YPDSF_0679 PTS permease protein YP_001873613.1 PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: ypp:YPDSF_0678 PTS permease protein YP_001873614.1 PFAM: PTS system fructose subfamily IIA component; KEGG: ypp:YPDSF_0677 PTS permease protein YP_001873615.1 TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; KEGG: ypp:YPDSF_0676 acetylglucosamine-6-phosphate deacetylase YP_001873616.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_001873617.1 PFAM: glycosyl hydrolase family 88; KEGG: ypi:YpsIP31758_0933 glycosyl hydrolase, family 88 YP_001873618.1 PFAM: Radical SAM domain protein; KEGG: ypi:YpsIP31758_0932 putative sulfatase regulator YP_001873619.1 PFAM: sulfatase; KEGG: yps:YPTB3086 putative sulfatase YP_001873621.1 KEGG: yps:YPTB3087 hypothetical protein YP_001873622.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_001873623.1 PFAM: ThiJ/PfpI domain protein; KEGG: yps:YPTB3089 ThiJ/PfpI-family thiamine biogenesis protein YP_001873624.1 KEGG: yps:YPTB3090 hypothetical protein YP_001873625.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypp:YPDSF_0668 LacI-family regulatory protein YP_001873626.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypi:YpsIP31758_0926 putative hexuronate transporter YP_001873627.1 PFAM: glycoside hydrolase family 31; KEGG: yps:YPTB3093 putative glucosidase-family 31 of glycosyl hydrolase YP_001873628.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_001873629.1 porin involved in the transport of maltose and maltodextrins YP_001873630.1 PFAM: phosphotransferase system PTS EIIB protein; KEGG: ypi:YpsIP31758_0919 PTS system, EIIB component YP_001873631.1 PFAM: Glycoside hydrolase family 42 domain protein; Beta-galactosidase trimerisation domain protein; Beta-galactosidase domain protein; KEGG: ypn:YPN_3054 putative beta-galactosidase YP_001873632.1 PFAM: glycosyl hydrolase 53 domain protein; KEGG: ypp:YPDSF_0660 galactosidase YP_001873633.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_0659 maltodextrin permease protein YP_001873634.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypn:YPN_3057 maltodextrin transport permease YP_001873635.1 PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_0914 maltose/maltodextrin ABC transporter, periplasmic maltose/maltodextrin-binding protein YP_001873636.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: ypn:YPN_3059 sugar transport ATP-binding protein YP_001873637.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_0912 ribose ABC transporter, ATP-binding protein YP_001873638.1 PFAM: inner-membrane translocator; KEGG: yps:YPTB3104 ABC sugar transporter, permease subunit YP_001873639.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ypp:YPDSF_0652 sugar-binding periplasmic protein YP_001873640.1 KEGG: yps:YPTB3106 hypothetical protein YP_001873641.1 KEGG: ypp:YPDSF_0650 lipoprotein YP_001873642.1 PFAM: transcriptional regulator PadR family protein; KEGG: yps:YPTB3108 hypothetical protein YP_001873643.1 KEGG: yps:YPTB3109 hypothetical protein YP_001873644.1 PFAM: PAAR repeat-containing protein; KEGG: ypi:YpsIP31758_0903 PaaR domain protein YP_001873645.1 KEGG: ypi:YpsIP31758_0902 hypothetical protein YP_001873646.1 KEGG: ypi:YpsIP31758_0901 hypothetical protein YP_001873647.1 KEGG: yps:YPTB3113 hypothetical protein YP_001873648.1 PFAM: Colicin D; KEGG: ypi:YpsIP31758_0899 hypothetical protein YP_001873649.1 KEGG: yps:YPTB3115 hypothetical protein YP_001873650.1 KEGG: ypp:YPDSF_0643 hypothetical protein YP_001873651.1 PFAM: S-type Pyocin domain protein; KEGG: yps:YPTB3116 hypothetical protein YP_001873652.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: ypi:YpsIP31758_0896 Fic family protein YP_001873653.1 KEGG: ypi:YpsIP31758_0895 hypothetical protein YP_001873654.1 KEGG: ypi:YpsIP31758_0894 hypothetical protein YP_001873655.1 PFAM: Prophage CP4-57 regulatory; KEGG: ypi:YpsIP31758_0893 AlpA family protein YP_001873656.1 KEGG: ypi:YpsIP31758_0892 hypothetical protein YP_001873657.1 KEGG: yps:YPTB3121 possible phage protein YP_001873658.1 PFAM: D5 protein; P4 alpha zinc-binding domain protein; primase P4; KEGG: ypi:YpsIP31758_0890 nucleoside triphosphatase, D5 family YP_001873659.1 SMART: helix-turn-helix domain protein; KEGG: ypi:YpsIP31758_0889 putative transcriptional regulator YP_001873660.1 KEGG: ypi:YpsIP31758_0888 hypothetical protein YP_001873661.1 PFAM: helix-turn-helix domain protein; KEGG: ypi:YpsIP31758_0887 helix-turn-helix DNA binding domain protein YP_001873662.1 PFAM: plasmid stabilization system; KEGG: yps:YPTB3126 possible bacteriophage protein YP_001873664.1 KEGG: ypg:YpAngola_A3854 hypothetical protein YP_001873665.1 PFAM: integrase family protein; KEGG: yps:YPTB3129 possible phage integrase/recombinase YP_001873666.1 PFAM: helix-turn-helix domain protein; KEGG: yps:YPTB3130 putative [Enterobacteria phage P2] YP_001873667.1 KEGG: yps:YPTB3131 probable bacteriophage Cox protein YP_001873668.1 KEGG: yen:YE0856 hypothetical phage-related protein YP_001873669.1 KEGG: yps:YPTB3132 hypothetical protein YP_001873672.1 KEGG: yen:YE0857A hypothetical phage-related protein YP_001873673.1 KEGG: yen:YE0858 hypothetical phage-related protein YP_001873674.1 KEGG: yen:YE0859 hypothetical phage-related protein YP_001873675.1 PFAM: protein of unknown function DUF437; KEGG: yps:YPTB3135 putative conserved bacteriophage protein YP_001873676.1 PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: yps:YPTB3136 putative conserved bacteriophage protein YP_001873677.1 KEGG: yen:YE0860A hypothetical phage-related protein YP_001873678.1 PFAM: replication gene A; KEGG: yps:YPTB3137 putative phage protein YP_001873679.1 PFAM: transcriptional activator Ogr/delta; KEGG: yen:YE0865 hypothetical phage-related protein YP_001873680.1 TIGRFAM: phage portal protein, PBSX family; PFAM: portal protein; KEGG: yen:YE0866 putative portal vertex protein YP_001873681.1 PFAM: protein of unknown function DUF264; putative terminase ATPase subunit; KEGG: yen:YE0867 terminase, ATPase subunit YP_001873682.1 PFAM: capsid scaffolding; KEGG: yen:YE0868 probable capsid scaffolding protein YP_001873683.1 TIGRFAM: phage major capsid protein, P2 family; PFAM: major capsid protein P2; KEGG: yen:YE0869 major capsid protein precursor YP_001873684.1 PFAM: small terminase subunit; KEGG: yen:YE0870 probable terminase, endonuclease subunit YP_001873685.1 PFAM: head completion protein; KEGG: yen:YE0871 head completion/stabilization protein YP_001873686.1 KEGG: yen:YE0871A hypothetical phage-related protein YP_001873687.1 KEGG: yen:YE0872 hypothetical phage-related protein YP_001873688.1 KEGG: yps:YPTB3147 hypothetical protein YP_001873689.1 KEGG: yps:YPTB3148 hypothetical protein YP_001873690.1 KEGG: yps:YPTB3149 possible phage P2 holin-like protein YP_001873691.1 KEGG: yps:YPTB3150 hypothetical protein YP_001873692.1 KEGG: yps:YPTB3151 hypothetical protein YP_001873693.1 KEGG: yps:YPTB3152 hypothetical protein YP_001873695.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: yps:YPTB3153 putative bacteriophage tail protein YP_001873696.1 KEGG: yps:YPTB3154 hypothetical protein YP_001873697.1 KEGG: yps:YPTB3155 putative bacteriophage protein YP_001873698.1 KEGG: yps:YPTB3156 putative bacteriophage protein YP_001873699.1 PFAM: tail fiber repeat 2 protein; KEGG: yps:YPTB3157 hypothetical protein YP_001873700.1 PFAM: tail assembly chaperone gp38; KEGG: yps:YPTB3158 putative bacteriophage protein YP_001873701.1 KEGG: yps:YPTB3159 possible bacteriophage protein YP_001873702.1 KEGG: yps:YPTB3160 hypothetical protein YP_001873703.1 KEGG: yps:YPTB3161 hypothetical protein YP_001873705.1 PFAM: integrase family protein; KEGG: ypi:YpsIP31758_0884 site-specific recombinase, phage integrase family YP_001873706.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001873707.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_001873708.1 5'-3' single-stranded-DNA-specific exonuclease YP_001873709.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_001873710.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001873711.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_001873712.1 PFAM: Inner membrane CreD family protein; KEGG: yps:YPTB3169 hypothetical protein YP_001873713.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_001873714.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_001873716.1 PFAM: protein of unknown function DUF339; KEGG: ypi:YpsIP31758_0873 hypothetical protein YP_001873717.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_001873718.1 KEGG: ypp:YPDSF_0616 membrane protein YP_001873719.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: yps:YPTB3176 putative hemolysin III YP_001873720.1 KEGG: ypi:YpsIP31758_0869 hypothetical protein YP_001873721.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: ypi:YpsIP31758_0868 haemagglutinin repeat protein YP_001873722.1 KEGG: ypi:YpsIP31758_0867 hypothetical protein YP_001873723.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001873724.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001873725.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001873727.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; KEGG: ypp:YPDSF_0606 monooxygenase YP_001873728.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_001873729.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_001873730.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_001873731.1 PFAM: protein of unknown function DUF710; KEGG: ypi:YpsIP31758_0858 hypothetical protein YP_001873732.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: ypp:YPDSF_0601 5-formyltetrahydrofolate cyclo-ligase-family protein YP_001873733.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001873734.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001873735.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001873736.1 PFAM: protein of unknown function DUF541; KEGG: ypp:YPDSF_0596 hypothetical protein YP_001873737.1 Involved in the export of arginine YP_001873738.1 PFAM: MscS Mechanosensitive ion channel; Conserved TM helix repeat-containing protein; KEGG: ypi:YpsIP31758_0851 transporter, small conductance mechanosensitive ion channel (MscS) family YP_001873739.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001873740.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001873741.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001873742.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001873743.1 PFAM: peptidase M48 Ste24p; KEGG: ypi:YpsIP31758_0845 peptidase, M48 family YP_001873744.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: ypi:YpsIP31758_0844 iron-sulfur cluster-binding protein, Rieske family YP_001873745.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001873747.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001873748.1 PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: yps:YPTB3204 hypothetical protein YP_001873749.1 PFAM: Endonuclease I; KEGG: ypp:YPDSF_0583 endonuclease I YP_001873750.1 KEGG: ypg:YpAngola_A3344 hypothetical protein YP_001873751.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001873752.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001873753.1 PFAM: protein of unknown function DUF179; KEGG: ypi:YpsIP31758_0835 hypothetical protein YP_001873754.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001873755.1 TIGRFAM: N-carbamoylputrescine amidase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: ypp:YPDSF_0577 carbon-nitrogen hydrolase YP_001873756.1 catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis YP_001873757.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: ypp:YPDSF_0575 hypothetical protein YP_001873758.1 PFAM: alanine racemase domain protein; KEGG: yps:YPTB3213 hypothetical protein YP_001873759.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001873760.1 KEGG: ypi:YpsIP31758_1148 hypothetical protein YP_001873761.1 PFAM: protein of unknown function YGGT; KEGG: ypg:YpAngola_A0140 putative YggT family membrane protein YP_001873762.1 PFAM: protein of unknown function DUF167; KEGG: ypg:YpAngola_A0141 conserved hypothetical protein TIGR00251 YP_001873763.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001873764.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001873765.1 KEGG: yps:YPTB3219 pore forming RTX toxin family protein YP_001873766.1 KEGG: yps:YPTB3220 hypothetical protein YP_001873767.1 catalyzes the formation of glutamate from glutamine YP_001873768.1 PFAM: protein of unknown function DUF469; KEGG: ypp:YPDSF_0564 hypothetical protein YP_001873769.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001873770.1 KEGG: ypm:YP_3489 adenine DNA glycosylase; TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001873771.1 PFAM: Fe(II) trafficking protein YggX; KEGG: ypi:YpsIP31758_0818 putative Fe(2+) trafficking protein YggX YP_001873772.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_001873774.1 PFAM: periplasmic binding protein; KEGG: ypp:YPDSF_0559 hypothetical protein YP_001873775.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ypp:YPDSF_0558 hydroxamate-type ferrisiderophore receptor YP_001873776.1 PFAM: inner-membrane translocator; KEGG: ypp:YPDSF_0557 sugar transport system permease protein YP_001873777.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB3230 ABC sugar transporter, fused ATP-binding domains YP_001873778.1 KEGG: yps:YPTB3231 putative sugar ABC transporter periplasmic binding protein YP_001873779.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: yps:YPTB3232 ornithine decarboxylase YP_001873780.1 KEGG: ypn:YPN_3160 integrase YP_001873781.1 KEGG: ypp:YPDSF_0551 hypothetical protein YP_001873782.1 PFAM: IS1 transposase; KEGG: ypi:YpsIP31758_0741 IS1 family transposase orfB YP_001873783.1 PFAM: Insertion element protein; KEGG: ypp:YPDSF_0549 insertion sequence protein YP_001873784.1 KEGG: ypi:YpsIP31758_0739 hypothetical protein YP_001873785.1 PFAM: Peptidase M23; KEGG: yps:YPTB3238 hypothetical protein YP_001873786.1 KEGG: ypi:YpsIP31758_2504 rhs element Vgr protein YP_001873787.1 KEGG: ypg:YpAngola_A0164 rhs element Vgr protein YP_001873788.1 PFAM: Insertion element protein; KEGG: yps:YPTB3242 insertion sequence protein YP_001873789.1 KEGG: yps:YPTB3243 hypothetical protein YP_001873790.1 PFAM: Peptidase M23; KEGG: ypm:YP_3469 hypothetical protein YP_001873791.1 TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: yps:YPTB3245 hypothetical protein YP_001873792.1 KEGG: yps:YPTB3246 Clp ATPase; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001873793.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: ypp:YPDSF_1505 hypothetical protein YP_001873794.1 PFAM: OmpA/MotB domain protein; KEGG: yps:YPTB3248 putative PAL/OmpA-family membrane protein YP_001873795.1 KEGG: yps:YPTB3249 possibly conserved membrane protein YP_001873796.1 TIGRFAM: type VI secretion protein, VC_A0114 family; PFAM: protein of unknown function DUF876; KEGG: ypp:YPDSF_0540 hypothetical protein YP_001873797.1 TIGRFAM: type VI secretion protein, EvpB/VC_A0108 family; PFAM: protein of unknown function DUF877; KEGG: ypp:YPDSF_1510 hypothetical protein YP_001873798.1 TIGRFAM: type VI secretion protein, VC_A0107 family; PFAM: conserved hypothetical protein; KEGG: ypp:YPDSF_1511 hypothetical protein YP_001873800.1 KEGG: ypn:YPN_3177 hypothetical protein YP_001873801.1 PFAM: Insertion element protein; KEGG: ypi:YpsIP31758_0724 IS1, transposase orfA YP_001873802.1 KEGG: ypp:YPDSF_0536 lipoprotein YP_001873803.1 PFAM: Abortive infection protein; KEGG: ypn:YPN_3181 membrane protein YP_001873806.1 PFAM: autoinducer synthesis protein; KEGG: ypi:YpsIP31758_0719 N-acylhomoserine lactone synthase YtbI YP_001873807.1 PFAM: regulatory protein LuxR; Autoinducer-binding domain protein; KEGG: ypi:YpsIP31758_0720 transcriptional regulator, LuxR family YP_001873808.1 KEGG: ypp:YPDSF_0532 hypothetical protein YP_001873809.1 PFAM: intradiol ring-cleavage dioxygenase; KEGG: yps:YPTB3261 hypothetical protein YP_001873810.1 PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB3262 MFS family efflux protein YP_001873811.1 PFAM: IucA/IucC family protein; KEGG: ypi:YpsIP31758_0714 aerobactin siderophore biosynthesis protein IucA YP_001873812.1 KEGG: yps:YPTB3264 putative siderophore biosynthesis protein IucB YP_001873813.1 PFAM: IucA/IucC family protein; KEGG: yps:YPTB3265 putative siderophore biosynthesis protein IucC YP_001873814.1 KEGG: ypi:YpsIP31758_0711 aerobactin siderophore biosynthesis protein IucD YP_001873815.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: yps:YPTB3267 putative ferric siderophore receptor YP_001873816.1 TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; KEGG: ypp:YPDSF_0523 sodium:galactoside symporter YP_001873817.1 KEGG: yps:YPTB3269 hypothetical protein YP_001873818.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypn:YPN_3197 LacI-family regulatory protein YP_001873819.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: ypi:YpsIP31758_0706 transporter, divalent anion:Na+ symporter (DASS) family YP_001873821.1 KEGG: yps:YPTB3272 hypothetical protein YP_001873822.1 KEGG: ypi:YpsIP31758_0704 hypothetical protein YP_001873823.1 KEGG: yps:YPTB3274 hypothetical protein YP_001873824.1 KEGG: yps:YPTB3275 hypothetical protein YP_001873825.1 KEGG: ypi:YpsIP31758_0701 hypothetical protein YP_001873826.1 KEGG: yps:YPTB3279 hypothetical protein YP_001873827.1 KEGG: yps:YPTB3280 hypothetical protein YP_001873828.1 KEGG: yps:YPTB3281 hypothetical protein YP_001873829.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; KEGG: yps:YPTB3282 hypothetical protein YP_001873830.1 KEGG: ypn:YPN_3202 hypothetical protein YP_001873831.1 TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; KEGG: yps:YPTB3284 hypothetical protein YP_001873832.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; KEGG: ypn:YPN_3204 outer membrane autotransporter barrel YP_001873833.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; KEGG: ypi:YpsIP31758_0694 putative autotransporter protein YP_001873834.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: ypn:YPN_3207 gluconate transporter YP_001873836.1 KEGG: ypi:YpsIP31758_0692 hypothetical protein YP_001873837.1 KEGG: yps:YPTB3289 hypothetical protein YP_001873838.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB3290 putative ABC iron siderophore transporter, fused permease and ATPase domains YP_001873839.1 PFAM: ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_0689 ABC transporter, permease/ATP-binding protein YP_001873840.1 PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB3292 MFS family, AmpG related permease YP_001873841.1 PFAM: Thioesterase; KEGG: yps:YPTB3293 putative thioesterase YP_001873842.1 TIGRFAM: thiazolinyl imide reductase; PFAM: oxidoreductase domain protein; KEGG: yps:YPTB3294 hypothetical protein YP_001873843.1 PFAM: Saccharopine dehydrogenase; KEGG: yps:YPTB3295 hypothetical protein YP_001873844.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; Methyltransferase type 11; Methyltransferase type 12; Non-ribosomal peptide synthetase; KEGG: yps:YPTB3296 putative siderophore biosysnthesis protein YP_001873845.1 TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Non-ribosomal peptide synthetase; Beta-ketoacyl synthase; KEGG: yps:YPTB3297 possible high molecular weight siderophore biosynthesis protein YP_001873846.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: yps:YPTB3298 TonB-dependent O.M. iron siderophore receptor/tranporter YP_001873847.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001873848.1 PFAM: AbgT putative transporter; KEGG: ypn:YPN_3224 integral membrane efflux protein YP_001873850.1 KEGG: yps:YPTB3301 putative antigenic leucine-rich repeat protein YP_001873851.1 TIGRFAM: outer membrane autotransporter barrel domain protein; autotransporter-associated beta strand repeat protein; PFAM: Pertactin; Autotransporter beta- domain protein; Haemagluttinin repeat-containing protein; KEGG: yps:YPTB3303 putative pertactin family virulence factor/autotransporter YP_001873852.1 KEGG: yps:YPTB3304 hypothetical protein YP_001873853.1 PFAM: ShET2 enterotoxin domain protein; KEGG: yps:YPTB3305 enterotoxin-like protein YP_001873854.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: yps:YPTB3306 RND family drug efflux pump YP_001873855.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: yps:YPTB3307 HlyD family drug efflux protein YP_001873856.1 KEGG: yps:YPTB3308 conserved putative membrane protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; CHASE4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001873857.1 KEGG: yps:YPTB3938 IS1661 DNA-binding protein YP_001873858.1 PFAM: Integrase catalytic region; KEGG: ypa:YPA_3353 transposase for insertion sequence IS1661 YP_001873859.1 PFAM: 17 kDa surface antigen; KEGG: yps:YPTB3313 putative outer membrane lipoprotein Pcp precursor YP_001873860.1 PFAM: protein of unknown function DUF805; KEGG: ypm:YP_3060 uncharacterized membrane protein YP_001873861.1 KEGG: yps:YPTB3315 hypothetical protein YP_001873862.1 KEGG: ypa:YPA_3042 hypothetical protein YP_001873863.1 PFAM: OmpA/MotB domain protein; KEGG: ypg:YpAngola_A0200 flagellar motor protein B YP_001873864.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001873865.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001873866.1 KEGG: yps:YPTB3321 possible flagellar biogenesis protein YP_001873867.1 PFAM: flagellar hook-length control protein; KEGG: yps:YPTB3322 putative flagellar hook-length control protein YP_001873868.1 KEGG: yps:YPTB3323 hypothetical protein YP_001873869.1 PFAM: flagellar protein FliS; KEGG: yps:YPTB3324 putative flagellar protein YP_001873870.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; KEGG: yps:YPTB3325 putative flagellar hook-associated protein YP_001873871.1 PFAM: flagellin domain protein; KEGG: yps:YPTB3326 putative flagellin YP_001873872.1 PFAM: flagellin domain protein; KEGG: ypi:YpsIP31758_0654 flagellin YP_001873873.1 PFAM: transcriptional regulator domain protein; KEGG: yps:YPTB3327 putative regulatory protein YP_001873874.1 KEGG: yps:YPTB3328 hypothetical protein YP_001873875.1 KEGG: yps:YPTB3329 hypothetical protein YP_001873876.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; in Vibrio parahaemolyticus the protein in this cluster is associated with the lateral flagella YP_001873877.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001873878.1 FlgJ; flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; like the lateral flagella FlgJ in Vibrio parahaemolyticus this protein does not contains a C-terminal muramidase domain YP_001873879.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001873880.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; the Yersinia have 2 copies of flgH YP_001873881.1 makes up the distal portion of the flagellar basal body rod YP_001873882.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001873883.1 the hook connects flagellar basal body to the flagellar filament; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001873884.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Vibrio parahaemolyticus protein in this cluster is associated with lateral flagella production YP_001873885.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001873886.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Yersinia has 2 copies of flgB and other flagellar genes YP_001873887.1 required for the assembly of the flagellar basal body P-ring; the Vibrio parahaemolyticus protein involved with the synthesis of the lateral flagella YP_001873888.1 KEGG: yps:YPTB3342 putative flagellar regulatory protein YP_001873889.1 KEGG: yps:YPTB3343 hypothetical protein YP_001873890.1 TIGRFAM: flagellar export protein FliJ; KEGG: yps:YPTB3344 hypothetical protein YP_001873891.1 involved in type III protein export during flagellum assembly YP_001873892.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001873893.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001873894.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; the Vibrio parahaemolyticus protein is associated with the lateral flagella YP_001873895.1 PFAM: flagellar hook-basal body complex protein FliE; KEGG: yps:YPTB3349 possible flagellar hook-basal body complex protein YP_001873896.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: ypp:YPDSF_0496 sigma-54 transcriptional regulatory protein YP_001873897.1 KEGG: yps:YPTB3351 putative flagellar motor switch protein YP_001873898.1 TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; KEGG: yps:YPTB3352 flagellar switch protein YP_001873899.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001873900.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ family 3; KEGG: yps:YPTB3354 putative flagellar assembly/export protein, FliQ YP_001873901.1 TIGRFAM: flagellar biosynthetic protein FliR; PFAM: type III secretion system inner membrane R protein; KEGG: ypk:y3471 flagellar biosynthetic protein YP_001873902.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001873903.1 membrane protein involved in the flagellar export apparatus YP_001873904.1 KEGG: pfa:PFD0970c hypothetical protein YP_001873905.1 KEGG: ypp:YPDSF_0487 lipoprotein YP_001873906.1 KEGG: ypi:YpsIP31758_0619 hypothetical protein YP_001873907.1 with FepCDG is involved in the transport of ferric enterobactin YP_001873908.1 PFAM: Fimbrial protein; KEGG: ypi:YpsIP31758_0616 fimbrial family protein YP_001873909.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: ypi:YpsIP31758_0615 chaperone protein PapD YP_001873910.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: ypp:YPDSF_0481 outer membrane usher protein YP_001873911.1 PFAM: Fimbrial protein; KEGG: yps:YPTB3364 putative mannose-resistant Proteus-like fimbrial protein YP_001873913.1 PFAM: glycoside hydrolase family 18; Fibronectin type III domain protein; KEGG: yps:YPTB3365 putative Serratia marcescens-like C1 chitinase YP_001873914.1 PFAM: Carbohydrate-binding family V/XII; Fibronectin type III domain protein; chitin-binding domain 3 protein; KEGG: yps:YPTB3366 hypothetical protein YP_001873915.1 KEGG: sec:SC161 TnpA YP_001873916.1 KEGG: yps:YPTB3368 hypothetical protein YP_001873917.1 KEGG: yps:YPTB3369 hypothetical protein YP_001873918.1 PFAM: peptidase A24A prepilin type IV; KEGG: yps:YPTB3370 hypothetical protein YP_001873919.1 KEGG: yps:YPTB3371 putative membrane protein YP_001873920.1 PFAM: type II and III secretion system protein; KEGG: yps:YPTB3372 putative outer membrane secretin family protein YP_001873921.1 KEGG: ypg:YpAngola_A0258 hypothetical protein YP_001873922.1 KEGG: ypi:YpsIP31758_0600 hypothetical protein YP_001873923.1 PFAM: type II secretion system protein E; KEGG: ypp:YPDSF_0474 type II secretion protein YP_001873924.1 PFAM: type II secretion system protein; KEGG: yps:YPTB3376 putative integral membrane protein YP_001873925.1 PFAM: type II secretion system protein; KEGG: ypp:YPDSF_0472 hypothetical protein YP_001873926.1 KEGG: yps:YPTB3378 hypothetical protein YP_001873927.1 KEGG: ypi:YpsIP31758_0596 putative lipoprotein YP_001873928.1 PFAM: TadE family protein; KEGG: yps:YPTB3379 hypothetical protein YP_001873929.1 KEGG: ypi:YpsIP31758_0594 hypothetical protein YP_001873930.1 KEGG: ypi:YpsIP31758_0593 hypothetical protein YP_001873932.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_001873933.1 TIGRFAM: tonB-system energizer ExbB; PFAM: MotA/TolQ/ExbB proton channel; KEGG: ypm:YP_2997 TonB complex protein YP_001873934.1 catalyzes the formation of L-homocysteine from cystathionine YP_001873935.1 PFAM: SNARE associated Golgi protein; KEGG: ypi:YpsIP31758_0589 hypothetical protein YP_001873936.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC-type transcriptional regulator domain protein; KEGG: ypi:YpsIP31758_0588 transcriptional regulator, AraC family YP_001873937.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: ypi:YpsIP31758_0587 alcohol dehydrogenase, iron-containing YP_001873938.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_001873939.1 PFAM: Radical SAM domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: yps:YPTB3389 hypothetical protein YP_001873940.1 PFAM: multicopper oxidase type 2; multicopper oxidase type 3; KEGG: yps:YPTB3390 repressor protein for FtsI YP_001873942.1 TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; KEGG: ypp:YPDSF_0455 acyltransferase YP_001873943.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001873944.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: ypi:YpsIP31758_0580 putative NADH-quinone reductase MdaB YP_001873945.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypi:YpsIP31758_0579 substrate-binding transcriptional regulator, LysR family YP_001873946.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001873947.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_001873948.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase domain protein; KEGG: yps:YPTB3397 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_001873949.1 PFAM: protein of unknown function DUF1249; KEGG: ypp:YPDSF_0447 hypothetical protein YP_001873950.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001873951.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001873952.1 KEGG: ypm:YP_2977 hypothetical protein YP_001873953.1 KEGG: ypp:YPDSF_0444 hypothetical protein YP_001873954.1 PFAM: glutathionylspermidine synthase; KEGG: yps:YPTB3402 hypothetical protein YP_001873955.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_001873956.1 DHBP synthase; functions during riboflavin biosynthesis YP_001873957.1 KEGG: ypm:YP_2972 hypothetical protein YP_001873958.1 PFAM: protein of unknown function DUF526; KEGG: ypi:YpsIP31758_0566 hypothetical protein YP_001873959.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_001873960.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001873961.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001873962.1 PFAM: adenylate cyclase; KEGG: ypp:YPDSF_0436 hypothetical protein YP_001873963.1 SMART: SH3 domain protein; KEGG: ypi:YpsIP31758_0561 hypothetical protein YP_001873965.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_001873966.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001873967.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_001873968.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001873969.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001873970.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001873971.1 synthesizes RNA primers at the replication forks YP_001873972.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001873973.1 KEGG: pna:Pnap_4010 hypothetical protein YP_001873974.1 KEGG: plu:plu3488 hypothetical protein YP_001873975.1 KEGG: plu:plu4050 hypothetical protein YP_001873976.1 KEGG: plu:plu4051 hypothetical protein YP_001873977.1 KEGG: spt:SPA2604 putative phage gene YP_001873978.1 KEGG: yps:YPTB1820 putative phage tail fiber assembly protein YP_001873979.1 PFAM: tail fiber repeat 2 protein; KEGG: yen:YE0883 probable tail fiber protein YP_001873980.1 KEGG: yen:YE0882 hypothetical phage-related protein YP_001873981.1 KEGG: spt:SPA2608 putative phage gene YP_001873982.1 KEGG: spt:SPA2609 putative phage gene YP_001873983.1 TIGRFAM: phage tail tape measure protein, TP901 family; KEGG: spt:SPA2610 putative phage gene YP_001873984.1 KEGG: spt:SPA2611 putative phage gene YP_001873985.1 KEGG: yps:YPTB3151 hypothetical protein YP_001873986.1 KEGG: yps:YPTB3150 hypothetical protein YP_001873987.1 PFAM: holin family 2; KEGG: spt:SPA2612 putative phage gene YP_001873988.1 KEGG: spt:SPA2613 putative phage gene YP_001873989.1 KEGG: spt:SPA2614 putative phage gene YP_001873990.1 KEGG: spt:SPA2615 putative phage gene YP_001873991.1 KEGG: spt:SPA2616 putative phage gene YP_001873992.1 PFAM: head completion protein; KEGG: spt:SPA2617 putative phage gene YP_001873993.1 PFAM: small terminase subunit; KEGG: yps:YPTB3143 hypothetical protein YP_001873994.1 TIGRFAM: phage major capsid protein, P2 family; PFAM: major capsid protein P2; KEGG: spt:SPA2619 putative phage gene YP_001873995.1 KEGG: yen:YE0868 probable capsid scaffolding protein YP_001873996.1 PFAM: protein of unknown function DUF264; putative terminase ATPase subunit; KEGG: spt:SPA2620 putative phage gene YP_001873997.1 TIGRFAM: phage portal protein, PBSX family; PFAM: portal protein; KEGG: sgl:SG0244 putative phage capsid portal protein YP_001873998.1 PFAM: transcriptional activator Ogr/delta; KEGG: spt:SPA2622 putative phage gene YP_001873999.1 PFAM: replication gene A; KEGG: spt:SPA2623 putative phage gene YP_001874003.1 KEGG: yen:YE0857A hypothetical phage-related protein YP_001874004.1 PFAM: regulatory CII family protein; KEGG: spt:SPA2625 putative phage gene YP_001874005.1 KEGG: stt:t3403 hypothetical protein YP_001874006.1 PFAM: CI repressor; KEGG: sgl:SG0238 hypothetical protein YP_001874007.1 KEGG: mmr:Mmar10_0570 hypothetical protein YP_001874008.1 PFAM: integrase family protein; KEGG: kpn:KPN_04894 putative prophage gp Int for integrase YP_001874009.1 KEGG: yps:YPTB3419 hypothetical protein YP_001874010.1 KEGG: yps:YPTB3420 hypothetical protein YP_001874011.1 KEGG: yps:YPTB3421 hypothetical protein YP_001874012.1 PFAM: HNH endonuclease; KEGG: yps:YPTB3422 hypothetical protein YP_001874013.1 KEGG: ypm:YP_2951 hypothetical protein YP_001874014.1 KEGG: ypg:YpAngola_A0311 hypothetical protein YP_001874015.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: ypi:YpsIP31758_0548 Fic family protein YP_001874016.1 KEGG: ypk:y3546 hypothetical protein YP_001874017.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB3424 LysR-family regulatory protein YP_001874018.1 KEGG: yps:YPTB3425 hypothetical protein YP_001874019.1 PFAM: Putative mono-oxygenase ydhR; KEGG: ypi:YpsIP31758_0544 putative monooxygenase, YdhR YP_001874020.1 PFAM: Endoribonuclease L-PSP; KEGG: ypp:YPDSF_0413 translational inhibitor protein YP_001874021.1 TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: yps:YPTB3428 putative translational inhibitor protein YP_001874022.1 PFAM: YheO domain protein; KEGG: ypi:YpsIP31758_0541 hypothetical protein YP_001874023.1 KEGG: ypi:YpsIP31758_0540 hypothetical protein YP_001874024.1 KEGG: ypi:YpsIP31758_0539 Na+/H+ antiporter family protein YP_001874025.1 PFAM: aminotransferase class I and II; KEGG: ypp:YPDSF_0407 aminotransferase YP_001874026.1 KEGG: ypi:YpsIP31758_0537 hypothetical protein YP_001874027.1 KEGG: ypp:YPDSF_0405 hypothetical protein YP_001874028.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001874029.1 PFAM: Fusaric acid resistance protein conserved region; KEGG: ypi:YpsIP31758_0534 fusaric acid resistance domain protein YP_001874030.1 PFAM: outer membrane efflux protein; KEGG: ypn:YPN_0480 membrane protein YP_001874031.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: yps:YPTB3439 putative glycosyl hydrolase YP_001874032.1 KEGG: ypi:YpsIP31758_0531 hypothetical protein YP_001874033.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_0530 sugar ABC transporter, permease protein YP_001874034.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_0398 permease protein YP_001874035.1 PFAM: extracellular solute-binding protein family 1; KEGG: ypp:YPDSF_0397 sugar binding protein YP_001874036.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_0527 sugar-binding transcriptional regulator, LacI family YP_001874037.1 KEGG: ypa:YPA_3180 hypothetical protein YP_001874038.1 PFAM: ABC transporter related; TOBE domain protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: ypm:YP_2927 putative transporter ATP-binding protein YP_001874039.1 KEGG: yps:YPTB3447 hypothetical protein YP_001874040.1 KEGG: ypi:YpsIP31758_0523 hypothetical protein YP_001874041.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; KEGG: yps:YPTB3449 putative autotransporter protein YP_001874042.1 KEGG: ypi:YpsIP31758_0514 hypothetical protein YP_001874043.1 KEGG: ypi:YpsIP31758_0513 hypothetical protein YP_001874044.1 KEGG: ypi:YpsIP31758_0512 hypothetical protein YP_001874045.1 KEGG: ypi:YpsIP31758_0511 hypothetical protein YP_001874046.1 KEGG: yps:YPTB3453 hypothetical protein YP_001874047.1 KEGG: ypi:YpsIP31758_0510 adhesin/haemagluttinin repeat protein YP_001874048.1 PFAM: protein of unknown function DUF1436; KEGG: yps:YPTB3455 hypothetical protein YP_001874049.1 KEGG: yps:YPTB3460 possible adhesin/hemolysin YP_001874050.1 KEGG: spe:Spro_4401 hypothetical protein YP_001874051.1 KEGG: yps:YPTB3460 possible adhesin/hemolysin YP_001874052.1 KEGG: ypi:YpsIP31758_0520 hypothetical protein YP_001874053.1 KEGG: ypi:YpsIP31758_0519 hypothetical protein YP_001874054.1 KEGG: cko:CKO_03605 hypothetical protein YP_001874055.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: yps:YPTB3460 possible adhesin/hemolysin YP_001874056.1 PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: yps:YPTB3461 putative hemolysin activator/exporter YP_001874057.1 PFAM: von Willebrand factor type A; KEGG: ypi:YpsIP31758_0508 putative tellurium resistance protein YP_001874058.1 PFAM: stress protein; KEGG: ypi:YpsIP31758_0507 tellurium resistance protein YP_001874059.1 PFAM: von Willebrand factor type A; KEGG: yps:YPTB3464 putative TerY-like tellurite resistance protein YP_001874060.1 PFAM: von Willebrand factor type A; KEGG: ypi:YpsIP31758_0505 putative tellurium resistance protein YP_001874061.1 KEGG: yps:YPTB3466 hypothetical protein YP_001874062.1 KEGG: yps:YPTB3467 putative kinase protein YP_001874063.1 KEGG: ypp:YPDSF_0377 membrane protein YP_001874064.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: yps:YPTB3469 2,4-dienoyl-CoA reductase YP_001874065.1 PFAM: methyltransferase small; KEGG: ypn:YPN_0457 methyltransferase YP_001874066.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: yps:YPTB3471 putative pertactin family virulence factor/autotransporter YP_001874067.1 PFAM: protein of unknown function DUF45; KEGG: ypi:YpsIP31758_0498 hypothetical protein YP_001874068.1 PFAM: oxidoreductase domain protein; KEGG: yps:YPTB3473 possible MocA-family oxidoreductase YP_001874069.1 involved in the import of serine and threonine coupled with the import of sodium YP_001874070.1 KEGG: ypp:YPDSF_0369 membrane protein YP_001874071.1 PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; KEGG: ypi:YpsIP31758_0493 altronate dehydratase YP_001874072.1 catalyzes the formation of D-tagaturonate from D-altronate YP_001874073.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_001874074.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: yps:YPTB3479 ExuT transport protein, MFS superfamily YP_001874075.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_001874076.1 KEGG: yps:YPTB3481 putative lipoprotein YP_001874077.1 PFAM: SNARE associated Golgi protein; KEGG: ypi:YpsIP31758_0487 hypothetical protein YP_001874078.1 KEGG: ypi:YpsIP31758_0486 hypothetical protein YP_001874079.1 PFAM: protein of unknown function DUF1090; KEGG: ypi:YpsIP31758_0485 hypothetical protein YP_001874080.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: ypi:YpsIP31758_0483 hypothetical protein YP_001874081.1 KEGG: ypp:YPDSF_0356 hypothetical protein YP_001874082.1 KEGG: ypi:YpsIP31758_0481 hypothetical protein YP_001874083.1 PFAM: DoxX family protein; KEGG: ypp:YPDSF_0354 membrane protein YP_001874084.1 KEGG: yps:YPTB3489 possible glutathione S-transferase YP_001874085.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: yps:YPTB3490 LysR-family transcriptional regulatory protein YP_001874086.1 PFAM: Pirin domain protein; KEGG: ypi:YpsIP31758_0477 YhhW family protein YP_001874087.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: ypp:YPDSF_0350 tetrapyrrole methylase YP_001874088.1 PFAM: LppC family lipoprotein; KEGG: yps:YPTB3493 hypothetical protein YP_001874089.1 PFAM: protein of unknown function UPF0102; KEGG: ypi:YpsIP31758_0474 hypothetical protein YP_001874090.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_001874091.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region; KEGG: yps:YPTB3496 hypothetical protein YP_001874092.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001874093.1 PFAM: ThiJ/PfpI domain protein; KEGG: ypn:YPN_3436 enhancing lycopene biosynthesis protein 2 YP_001874094.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_001874096.1 KEGG: ypm:YP_3810 uncharacterized Fe-S oxidoreductase; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001874097.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001874098.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001874099.1 KEGG: ypi:YpsIP31758_0464 hypothetical protein YP_001874100.1 PFAM: Stringent starvation protein B; KEGG: ypp:YPDSF_0337 stringent starvation protein B YP_001874101.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001874102.1 forms a direct contact with the tRNA during translation YP_001874103.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001874104.1 PFAM: AFG1-family ATPase; KEGG: ypp:YPDSF_0333 hypothetical protein YP_001874106.1 PFAM: protein of unknown function DUF1043; KEGG: ypi:YpsIP31758_0457 hypothetical protein YP_001874107.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: ypp:YPDSF_0331 protease YP_001874108.1 TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: ypp:YPDSF_0329 protease YP_001874109.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001874110.1 PFAM: BolA family protein; KEGG: yps:YPTB3514 putative BolA/YrbA family protein YP_001874111.1 KEGG: ypp:YPDSF_0326 anti-sigma B factor antagonist YP_001874112.1 PFAM: toluene tolerance family protein; KEGG: ypp:YPDSF_0325 hypothetical protein YP_001874113.1 PFAM: Mammalian cell entry related domain protein; KEGG: ypi:YpsIP31758_0450 mce family protein YP_001874114.1 PFAM: protein of unknown function DUF140; KEGG: ypp:YPDSF_0323 membrane protein YP_001874115.1 ATP-binding subunit of a putative ABC toluene efflux transporter YP_001874116.1 YrbG; inner membrane protein involved in cell envelope integrity; putative sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_001874117.1 TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: ypp:YPDSF_0320 hypothetical protein YP_001874118.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001874119.1 PFAM: protein of unknown function DUF1239; KEGG: ypi:YpsIP31758_0444 hypothetical protein YP_001874120.1 LptA; periplasmic binding protein part of a putative ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_001874121.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypn:YPN_3463 ABC transporter ATP-binding protein YP_001874122.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001874123.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_001874124.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: ypp:YPDSF_0312 nitrogen regulatory IIA protein YP_001874125.1 PFAM: conserved hypothetical protein; KEGG: ypp:YPDSF_0311 hypothetical protein YP_001874126.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: ypp:YPDSF_0310 phosphocarrier protein YP_001874127.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001874128.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_001874129.1 TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: ypi:YpsIP31758_0434 putative endoribonuclease L-PSP YP_001874130.1 KEGG: ypi:YpsIP31758_0433 hypothetical protein YP_001874131.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_001874132.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_001874133.1 KEGG: ypp:YPDSF_0303 trehalose-6-phosphate hydrolase; TIGRFAM: alpha,alpha-phosphotrehalase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain YP_001874134.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_001874135.1 PFAM: cytochrome b562; KEGG: ypp:YPDSF_0301 cytochrome YP_001874136.1 KEGG: ypi:YpsIP31758_0427 hypothetical protein YP_001874137.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_001874138.1 PFAM: protein of unknown function DUF615; KEGG: ypi:YpsIP31758_0425 hypothetical protein YP_001874139.1 PFAM: Barstar (barnase inhibitor); KEGG: ypi:YpsIP31758_0424 barstar YP_001874140.1 PFAM: guanine-specific ribonuclease N1 and T1; KEGG: ypp:YPDSF_0296 ribonuclease YP_001874141.1 TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase_; KEGG: ypi:YpsIP31758_0422 succinate-semialdehyde dehydrogenase (NADP+) YP_001874142.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001874143.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_001874144.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_001874145.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ypp:YPDSF_0290 LysR-family transcriptional regulatory protein YP_001874146.1 PFAM: regulatory protein LysR; KEGG: yps:YPTB3550 putative LysR-family transcriptional regulatory protein YP_001874147.1 PFAM: virulence plasmid 28.1 kDa A protein; KEGG: yps:YPTB3551 putative insecticial toxin YP_001874148.1 KEGG: yps:YPTB3552 putative insecticidal toxin complex protein YP_001874149.1 PFAM: virulence plasmid 65kDa B protein; FG-GAP repeat protein; KEGG: yps:YPTB3553 insecticidal toxin complex YP_001874150.1 KEGG: ypp:YPDSF_0284 hypothetical protein YP_001874151.1 KEGG: yps:YPTB3555 putative phage-related protein YP_001874152.1 KEGG: yps:YPTB3556 hypothetical protein YP_001874153.1 KEGG: ypm:YP_3870 hypothetical protein YP_001874154.1 TIGRFAM: YD repeat protein; KEGG: yps:YPTB3557 putative insecticidal toxin YP_001874155.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_001874156.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: ypp:YPDSF_0278 carbon-nitrogen hydrolase YP_001874157.1 KEGG: yps:YPTB3560 hypothetical protein YP_001874158.1 involved in the processing of the 5'end of 16S rRNA YP_001874159.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001874160.1 part of cell wall structural complex MreBCD; transmembrane component YP_001874161.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001874162.1 functions in MreBCD complex in some organisms YP_001874163.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001874164.1 TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ypp:YPDSF_0270 zinc-binding dehydrogenase YP_001874165.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001874166.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001874167.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001874168.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001874169.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001874171.1 PFAM: protein of unknown function DUF997; KEGG: ypp:YPDSF_0264 membrane protein YP_001874172.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_001874173.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001874174.1 TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; dihydroorotate dehydrogenase; KEGG: ypi:YpsIP31758_0386 dihydrouridine synthase YP_001874175.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001874176.1 KEGG: ypi:YpsIP31758_0384 hypothetical protein YP_001874177.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: ypi:YpsIP31758_0383 transcriptional regulator, GntR family YP_001874178.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: yps:YPTB3580 MFS family metabolite symporter YP_001874179.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: yps:YPTB3581 putative gamma carboxymuconolactone decarboxylase YP_001874180.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: ypi:YpsIP31758_0380 6-phosphogluconate dehydrogenase NAD-binding domain protein YP_001874181.1 PFAM: beta-lactamase domain protein; KEGG: yps:YPTB3583 hypothetical protein YP_001874182.1 PFAM: 17 kDa surface antigen; KEGG: ypp:YPDSF_0253 outer membrane lipoprotein YP_001874183.1 KEGG: ypm:YP_3902 hypothetical protein YP_001874184.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ypi:YpsIP31758_0376 cold shock DNA-binding domain protein YP_001874185.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ypi:YpsIP31758_0376 cold shock DNA-binding domain protein YP_001874186.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: yps:YPTB3587 major cold shock protein CspA2 YP_001874187.1 KEGG: yps:YPTB3588 hypothetical protein YP_001874189.1 KEGG: yps:YPTB3589 hypothetical protein YP_001874190.1 YghU; B2989; one of eight putative glutathione transferase proteins from E. coli YP_001874191.1 PFAM: sugar isomerase (SIS); KEGG: ypi:YpsIP31758_0369 SIS domain protein YP_001874192.1 TIGRFAM: FGGY-family pentulose kinase; PFAM: carbohydrate kinase FGGY; KEGG: ypp:YPDSF_0244 carbohydrate kinase YP_001874193.1 PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_0367 carbohydrate uptake (CUT2 family) ABC transporter, permease protein YP_001874194.1 PFAM: inner-membrane translocator; KEGG: yps:YPTB3594 ABC sugar transporter, permease subunit YP_001874195.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypp:YPDSF_0241 ABC transporter ATP binding protein YP_001874196.1 KEGG: ypp:YPDSF_0240 periplasmic binding protein YP_001874197.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_001874198.1 KEGG: yps:YPTB3598 hypothetical protein YP_001874199.1 TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; KEGG: ypp:YPDSF_0237 putative Na(+)/H(+) exchanger protein YP_001874200.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: yps:YPTB3600 putative xanthine/uracil permease YP_001874201.1 PFAM: RelB antitoxin; KEGG: ypi:YpsIP31758_0357 DNA-damage-inducible protein J YP_001874202.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_001874203.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypp:YPDSF_0233 aliphatic sulfonates transport permease protein YP_001874204.1 catalyzes the release of sulfite from alkanesulfonates YP_001874205.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease YP_001874206.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: ypp:YPDSF_0230 NAD(P)H-dependent FMN reductase YP_001874207.1 TIGRFAM: deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: ypi:YpsIP31758_0350 putative deoxyribose-phosphate aldolase YP_001874208.1 PFAM: PfkB domain protein; KEGG: yps:YPTB3608 probable carbohydrate kinase YP_001874209.1 PFAM: RbsD or FucU transport; KEGG: yps:YPTB3609 putative carbohydrate transport protein YP_001874210.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; KEGG: yps:YPTB3610 putative AraC-family transcriptional regulatory protein YP_001874211.1 PFAM: oxidoreductase domain protein; KEGG: ypi:YpsIP31758_0345 oxidoreductase, NAD-binding YP_001874212.1 PFAM: Xylose isomerase domain protein TIM barrel; KEGG: ypi:YpsIP31758_0344 AP endonuclease, family 2 YP_001874213.1 KEGG: yps:YPTB3613 putative rhs accessory genetic element YP_001874214.1 KEGG: yps:YPTB3614 hypothetical protein YP_001874215.1 TIGRFAM: YD repeat protein; PFAM: RHS protein; YD repeat-containing protein; PAAR repeat-containing protein; KEGG: yps:YPTB3615 hypothetical protein YP_001874216.1 PFAM: Domain of unknown function DUF1795; KEGG: ypi:YpsIP31758_0340 hypothetical protein YP_001874217.1 TIGRFAM: type VI secretion system Vgr family protein; PFAM: Rhs element Vgr protein; Gp5 domain protein; KEGG: yps:YPTB3617 putative rhs accessory genetic element YP_001874218.1 PFAM: ImpA domain protein; KEGG: ypi:YpsIP31758_0327 ImpA domain protein YP_001874219.1 TIGRFAM: type VI secretion protein IcmF; PFAM: ImcF domain protein; protein of unknown function DUF1215; KEGG: yps:YPTB3625 hypothetical protein YP_001874220.1 TIGRFAM: type VI secretion-associated protein, VC_A0119 family; PFAM: ImpA domain protein; KEGG: ypi:YpsIP31758_0325 ImpA domain protein YP_001874221.1 KEGG: yps:YPTB3627 hypothetical protein YP_001874222.1 PFAM: helix-turn-helix Fis-type; KEGG: ypp:YPDSF_0206 hypothetical protein YP_001874223.1 KEGG: ypn:YPN_3573 Clp ATPase; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001874224.1 KEGG: ypp:YPDSF_0204 membrane protein YP_001874225.1 TIGRFAM: type VI secretion protein, VC_A0114 family; PFAM: protein of unknown function DUF876; KEGG: ypp:YPDSF_0203 hypothetical protein YP_001874226.1 KEGG: ypp:YPDSF_0202 lipoprotein YP_001874227.1 KEGG: ypi:YpsIP31758_0318 FHA domain protein YP_001874228.1 TIGRFAM: type VI secretion protein, VC_A0111 family; PFAM: protein of unknown function DUF1305; KEGG: ypp:YPDSF_0200 hypothetical protein YP_001874229.1 TIGRFAM: type VI secretion protein, VC_A0110 family; PFAM: protein of unknown function DUF879; KEGG: ypi:YpsIP31758_0316 hypothetical protein YP_001874230.1 TIGRFAM: type VI secretion system lysozyme-related protein; PFAM: GPW/gp25 family protein; KEGG: ypi:YpsIP31758_0315 hypothetical protein YP_001874231.1 TIGRFAM: type VI secretion protein, EvpB/VC_A0108 family; PFAM: protein of unknown function DUF877; KEGG: ypi:YpsIP31758_0314 hypothetical protein YP_001874232.1 TIGRFAM: type VI secretion protein, VC_A0107 family; PFAM: conserved hypothetical protein; KEGG: yps:YPTB3638 hypothetical protein YP_001874233.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; KEGG: yps:YPTB3639 hypothetical protein YP_001874235.1 KEGG: yps:YPTB3640 hypothetical protein YP_001874236.1 PFAM: Maltose operon periplasmic; KEGG: yps:YPTB3641 maltose regulon periplasmic protein YP_001874237.1 porin involved in the transport of maltose and maltodextrins YP_001874238.1 with malEFG is involved in import of maltose/maltodextrin YP_001874239.1 KEGG: ypm:YP_3075 glycosidases YP_001874240.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_001874241.1 with MalKGE is involved in maltose transport into the cell YP_001874242.1 with MalKFE is involved in the transport of maltose into the cell YP_001874243.1 PFAM: phosphate-starvation-inducible E; KEGG: ypi:YpsIP31758_0303 protein PsiE YP_001874245.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001874246.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001874247.1 PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: ypp:YPDSF_0180 hemolysin activator protein YP_001874248.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; PFAM: Haemagluttinin repeat-containing protein; filamentous haemagglutinin domain protein; KEGG: yps:YPTB3652 hemolysin YP_001874249.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001874250.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_001874251.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_001874252.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: ypi:YpsIP31758_0295 isocitrate lyase YP_001874253.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001874254.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001874257.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: yps:YPTB3659 putative transferase YP_001874258.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001874259.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_001874260.1 PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: ypi:YpsIP31758_3879 topoisomerase DNA binding C4 zinc finger domain protein YP_001874261.1 PFAM: protein of unknown function DUF494; KEGG: ypi:YpsIP31758_3880 smg protein YP_001874262.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: yps:YPTB3664 hypothetical protein YP_001874263.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001874264.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001874265.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_001874266.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001874267.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001874268.1 PFAM: protein of unknown function DUF331; KEGG: ypi:YpsIP31758_3887 hypothetical protein YP_001874269.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001874270.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001874271.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001874272.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001874273.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001874274.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001874275.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001874276.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001874277.1 late assembly protein YP_001874278.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001874279.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001874280.1 binds 5S rRNA along with protein L5 and L25 YP_001874281.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001874282.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001874283.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001874284.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001874285.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001874286.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001874287.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001874288.1 one of the stabilizing components for the large ribosomal subunit YP_001874289.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001874290.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001874291.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001874292.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001874293.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001874294.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001874295.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001874296.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001874297.1 PFAM: ribosomal protein S10; KEGG: ypp:YPDSF_0132 30S ribosomal protein S10 YP_001874298.1 iron storage protein YP_001874299.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: yps:YPTB3701 bacterioferritin-associated ferredoxin YP_001874300.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001874301.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001874302.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001874303.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001874304.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001874305.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001874306.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_001874307.1 PFAM: YheO domain protein; KEGG: ypi:YpsIP31758_3925 hypothetical protein YP_001874308.1 rotamase YP_001874309.1 PFAM: SlyX family protein; KEGG: ypi:YpsIP31758_3927 SlyX protein YP_001874310.1 rotamase YP_001874311.1 PFAM: conserved hypothetical protein; KEGG: ypi:YpsIP31758_3929 hypothetical protein YP_001874312.1 involved in potassium efflux YP_001874313.1 required for KefB activity YP_001874314.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypp:YPDSF_0114 ATPase YP_001874315.1 PFAM: glycosyl transferase family 2; KEGG: yps:YPTB3717 putative glycosyl transferase YP_001874316.1 PFAM: glycosyl transferase family 9; KEGG: yps:YPTB3718 putative sugar transferase YP_001874317.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_001874318.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypi:YpsIP31758_3936 taurine ABC transporter, permease protein YP_001874319.1 Part of the ABC transporter complex tauABC involved in taurine import YP_001874320.1 with TauB and TauC is responsible for taurine uptake. YP_001874321.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: ypi:YpsIP31758_3939 translocator protein, LysE family YP_001874322.1 PFAM: alpha/beta hydrolase fold; KEGG: ypi:YpsIP31758_3940 hydrolase, alpha/beta fold family YP_001874323.1 PFAM: protein of unknown function UPF0270; KEGG: ypi:YpsIP31758_3941 hypothetical protein YP_001874324.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: ypi:YpsIP31758_3942 putative phosphoribulokinase YP_001874325.1 PFAM: protein of unknown function DUF1240; KEGG: yps:YPTB3727 hypothetical protein YP_001874326.1 PFAM: OsmC family protein; KEGG: ypi:YpsIP31758_3944 OsmC family protein YP_001874327.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001874328.1 TIGRFAM: integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: yps:YPTB3730 possible putative efflux transporter (PET) family protein YP_001874329.1 KEGG: ypi:YpsIP31758_1513 hypothetical protein YP_001874330.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001874331.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_001874332.1 PFAM: protein of unknown function DUF853 NPT hydrolase putative; KEGG: yps:YPTB3733 hypothetical protein YP_001874333.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: ypi:YpsIP31758_3950 peptidyl-prolyl cis-trans isomerase A YP_001874334.1 KEGG: ypg:YpAngola_A3708 hypothetical protein YP_001874335.1 PFAM: glycoside hydrolase family 4; KEGG: ypi:YpsIP31758_3951 6-phospho-beta-glucosidase YP_001874336.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_3952 sugar-binding transcriptional regulator, LacI family YP_001874337.1 TIGRFAM: TonB-dependent copper receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ypi:YpsIP31758_3953 TonB-dependent copper receptor OprC YP_001874338.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypp:YPDSF_0090 conserved integral membrane protein YP_001874339.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001874341.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: yps:YPTB3740 nitrite reductase YP_001874342.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_001874343.1 member of the FNT family of formate and nitrite transporters YP_001874344.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin YP_001874345.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001874346.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_001874347.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: ypp:YPDSF_0082 ribulose-phosphate 3-epimerase YP_001874348.1 TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; KEGG: ypi:YpsIP31758_3963 DNA adenine methylase YP_001874349.1 PFAM: Sporulation domain protein; KEGG: yps:YPTB3748 hypothetical protein YP_001874350.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001874351.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001874352.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_001874353.1 KEGG: ypp:YPDSF_0075 membrane protein YP_001874354.1 KEGG: ypp:YPDSF_0074 membrane protein YP_001874355.1 PFAM: Fimbrial assembly family protein; KEGG: yps:YPTB3754 hypothetical protein YP_001874356.1 KEGG: yps:YPTB3755 hypothetical protein YP_001874357.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_001874358.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001874359.1 KEGG: ypm:YP_0144 hypothetical protein YP_001874360.1 PFAM: Intracellular growth attenuator IgaA; KEGG: ypi:YpsIP31758_3974 intracellular growth attenuator family protein YP_001874361.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ypp:YPDSF_0068 hypothetical protein YP_001874362.1 PFAM: RNA-binding S4 domain protein; KEGG: ypi:YpsIP31758_3976 heat shock protein 15 YP_001874363.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001874364.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001874365.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_001874366.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001874367.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001874368.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: yps:YPTB3766 hypothetical protein YP_001874369.1 PFAM: FeoA family protein; KEGG: ypp:YPDSF_0060 hypothetical ferrous iron transport protein A YP_001874370.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_001874371.1 PFAM: Protein of unknown function DUF1920; KEGG: ypi:YpsIP31758_3986 hypothetical protein YP_001874372.1 PFAM: protein of unknown function DUF1471; KEGG: ypi:YpsIP31758_3987 hypothetical protein YP_001874373.1 TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold; KEGG: yps:YPTB3771 putative biotin biosynthesis protein YP_001874374.1 involved in high-affinity gluconate transport YP_001874375.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001874376.1 amylomaltase; acts to release glucose from maltodextrins YP_001874377.1 TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; KEGG: yps:YPTB3775 maltodextrin phosphorylase YP_001874378.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_001874379.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_001874380.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_001874381.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_001874383.1 PFAM: protein of unknown function DUF943; KEGG: yps:YPTB3781 hypothetical protein YP_001874384.1 KEGG: ypn:YPN_3584 hypothetical protein YP_001874385.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001874386.1 TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; KEGG: ypm:YP_3300 glycogen phosphorylase YP_001874387.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001874388.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001874389.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_001874390.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001874391.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; KEGG: yps:YPTB3788 hypothetical protein YP_001874392.1 TIGRFAM: conserved repeat domain protein; PFAM: Peptidoglycan-binding LysM; Ig domain protein group 1 domain protein; KEGG: yps:YPTB3789 possible bacterial Ig-like domain (group 1) YP_001874393.1 KEGG: mbu:Mbur_0296 hypothetical protein YP_001874394.1 KEGG: ypi:YpsIP31758_4010 hypothetical protein YP_001874395.1 KEGG: ypi:YpsIP31758_4011 hypothetical protein YP_001874396.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001874397.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_001874398.1 KEGG: ypi:YpsIP31758_4018 hypothetical protein YP_001874399.1 KEGG: ypi:YpsIP31758_4017 hypothetical protein YP_001874400.1 KEGG: yps:YPTB3795 hypothetical protein YP_001874401.1 TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase; KEGG: ypn:YPN_3602 gluconokinase YP_001874402.1 TIGRFAM: gluconate transporter; PFAM: Gluconate transporter; Citrate transporter; KEGG: yps:YPTB3797 putative indonate/gluconate permease, GntP family YP_001874403.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: ypi:YpsIP31758_4022 sugar-binding transcriptional regulator, LacI family YP_001874404.1 PFAM: Pirin domain protein; Cupin 2 conserved barrel domain protein; KEGG: ypn:YPN_3605 hypothetical protein YP_001874405.1 KEGG: ypn:YPN_3606 hypothetical protein YP_001874406.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ypn:YPN_3607 response regulator protein YP_001874407.1 PFAM: PfkB domain protein; KEGG: yps:YPTB3802 PfkB family carbohydrate kinase YP_001874408.1 TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; KEGG: ypi:YpsIP31758_4026 putative fructose-bisphosphate aldolase YP_001874409.1 PFAM: protein of unknown function DUF1498; KEGG: ypi:YpsIP31758_4027 hypothetical protein YP_001874410.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: ypi:YpsIP31758_4028 ribose ABC transporter, periplasmic ribose-binding protein YP_001874411.1 PFAM: inner-membrane translocator; KEGG: ypi:YpsIP31758_4029 ribose ABC transporter, permease protein YP_001874412.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ypi:YpsIP31758_4030 ribose ABC transporter, ATP-binding protein YP_001874413.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: yps:YPTB3808 putative hybrid two-component system regulatory protein YP_001874415.1 KEGG: ypi:YpsIP31758_3703 hypothetical protein YP_001874416.1 KEGG: ses:SARI_03080 hypothetical protein YP_001874418.1 KEGG: vvy:VVA0688 hypothetical protein YP_001874419.1 KEGG: shn:Shewana3_4355 hypothetical protein YP_001874420.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: shn:Shewana3_4354 UBA/ThiF-type NAD/FAD binding protein YP_001874421.1 KEGG: shn:Shewana3_4353 hypothetical protein YP_001874422.1 KEGG: shn:Shewana3_4352 hypothetical protein YP_001874423.1 KEGG: reh:H16_B1330 hypothetical protein YP_001874424.1 KEGG: tva:TVAG_192110 hypothetical protein Pfam: DEAD PROSITE: ILE_RICH YP_001874425.1 KEGG: sbl:Sbal_4321 hypothetical protein YP_001874426.1 SMART: AAA ATPase; KEGG: sbl:Sbal_4322 hypothetical protein YP_001874427.1 KEGG: sbl:Sbal_4326 hypothetical protein YP_001874428.1 PFAM: TnsA endonuclease; KEGG: sbl:Sbal_4327 Tn7-like transposition protein A YP_001874429.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ypn:YPN_3615 hypothetical protein YP_001874430.1 PFAM: phosphate transporter; KEGG: ypn:YPN_3616 phosphate transport protein YP_001874431.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_001874432.1 PFAM: UspA domain protein; KEGG: ypn:YPN_3619 universal stress protein A YP_001874433.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_001874434.1 PFAM: Hemolysin-type calcium-binding region; peptidase M10A and M12B matrixin and adamalysin; Peptidase M10 serralysin; SMART: peptidase metallopeptidase; KEGG: yps:YPTB3814 metalloprotease YP_001874435.1 predicted SAM-dependent methyltransferase YP_001874436.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F; KEGG: yps:YPTB3816 oligopeptidase A YP_001874437.1 PFAM: protein of unknown function DUF519; KEGG: ypi:YpsIP31758_4048 hypothetical protein YP_001874438.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001874439.1 PFAM: sugar diacid recognition domain protein; KEGG: yps:YPTB3819 putative regulatory protein YP_001874440.1 PFAM: Gluconate transporter; Citrate transporter; KEGG: ypi:YpsIP31758_4051 transporter, gluconate:H+ symporter (GntP) family YP_001874441.1 PFAM: glycerate kinase; KEGG: yps:YPTB3821 putative glycerate kinase YP_001874442.1 PFAM: protein of unknown function DUF943; KEGG: yps:YPTB3822 hypothetical protein YP_001874443.1 KEGG: ypp:YPDSF_3347 hypothetical protein YP_001874444.1 KEGG: ypp:YPDSF_3349 hypothetical protein YP_001874445.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: ypi:YpsIP31758_4055 putative autotransporter protein YP_001874446.1 TIGRFAM: ribonuclease; PFAM: ribonuclease BN; KEGG: yps:YPTB3825 hypothetical protein YP_001874447.1 PFAM: CDP-diacylglycerol pyrophosphatase; KEGG: yps:YPTB3826 CDP-diacylglycerol pyrophosphatase YP_001874448.1 PFAM: AsmA family protein; KEGG: ypi:YpsIP31758_4058 AsmA family protein YP_001874449.1 in Escherichia coli this protein is involved in flagellar function YP_001874450.1 TIGRFAM: 4-oxalocrotonate tautomerase family enzyme; PFAM: 4-oxalocrotonate tautomerase; KEGG: ypn:YPN_3639 tautomerase YP_001874451.1 PFAM: PfkB domain protein; KEGG: yps:YPTB3830 2-dehydro-3-deoxygluconokinase YP_001874452.1 PFAM: peptidase M16 domain protein; KEGG: ypn:YPN_3641 insulinase family protease YP_001874453.1 KEGG: ypg:YpAngola_A4068 hypothetical protein YP_001874454.1 involved in the transport of C4-dicarboxylates across the membrane YP_001874455.1 PFAM: coagulation factor 5/8 type domain protein; KEGG: ypi:YpsIP31758_4065 F5/8 type C domain protein YP_001874456.1 PFAM: periplasmic pectate lyase; KEGG: ypn:YPN_3644 periplasmic pectate lyase precursor YP_001874457.1 PFAM: Oligogalacturonate-specific porin; KEGG: ypi:YpsIP31758_4068 oligogalacturonate-specific porin protein KdgM YP_001874458.2 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein YP_001874459.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_001874460.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_001874461.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_001874462.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: ypn:YPN_3650 dipeptide transport system permease protein YP_001874463.1 transports peptides consisting of two or three amino acids YP_001874464.1 PFAM: extracellular solute-binding protein family 5; KEGG: yps:YPTB3842 ABC transporter, periplasmic dipeptide binding protein YP_001874465.1 KEGG: ypm:YP_3366 hypothetical protein YP_001874466.1 PFAM: Hemolysin activator HlyB domain protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: yps:YPTB3843 putative TPS family hemolysin activator/secretion protein YP_001874467.1 TIGRFAM: filamentous haemagglutinin family outer membrane protein; adhesin HecA family; PFAM: filamentous haemagglutinin domain protein; KEGG: yps:YPTB3844 hemagglutinin/hemolysin-related protein YP_001874468.1 membrane protein regulates uhpT expression YP_001874469.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_001874470.1 PFAM: regulatory protein LuxR; response regulator receiver; Sigma-70 region 4 type 2; KEGG: ypn:YPN_3660 two-component system response regulator YP_001874471.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_001874472.1 KEGG: ypn:YPN_3662 membrane protein YP_001874473.1 PFAM: amino acid permease-associated region; KEGG: yps:YPTB3850 APC family histidine permease YP_001874474.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001874475.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001874476.1 KEGG: ypi:YpsIP31758_4087 pyridoxal-phosphate dependent protein YP_001874477.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001874478.1 KEGG: ypi:YpsIP31758_4089 hypothetical protein YP_001874479.1 PFAM: phosphoribosylglycinamide synthetase; KEGG: yps:YPTB3856 hypothetical protein YP_001874480.1 PFAM: periplasmic binding protein; KEGG: ypi:YpsIP31758_4091 iron chelate ABC transporter, periplasmic iron-binding protein YP_001874481.1 PFAM: transport system permease protein; KEGG: yps:YPTB3858 ABC iron siderophore transporter, permease subunit YP_001874482.1 PFAM: transport system permease protein; KEGG: yps:YPTB3859 ABC iron siderophore transporter, permease subunit YP_001874483.1 PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: yps:YPTB3860 ABC iron siderophore transporter, ATP-binding subunit YP_001874484.1 KEGG: ypn:YPN_3674 hypothetical protein YP_001874485.1 KEGG: yps:YPTB3863 hypothetical protein YP_001874486.1 KEGG: yps:YPTB3865 hypothetical protein YP_001874487.1 PFAM: protein of unknown function DUF1219; KEGG: yps:YPTB3866 hypothetical protein YP_001874488.1 PFAM: YagBYeeUYfjZ family protein; KEGG: yps:YPTB3867 hypothetical protein YP_001874489.1 PFAM: DNA repair protein RadC; KEGG: yps:YPTB3868 hypothetical protein YP_001874490.1 KEGG: yps:YPTB3869 hypothetical protein YP_001874491.1 KEGG: yps:YPTB3870 hypothetical protein YP_001874492.1 KEGG: yps:YPTB3871 hypothetical protein YP_001874493.1 PFAM: IstB domain protein ATP-binding protein; KEGG: yps:YPTB3872 putative IS100 transposase YP_001874494.1 KEGG: yps:YPTB3873 hypothetical protein YP_001874495.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: ypp:YPDSF_2254 insertion sequence IS100, ATP-binding protein YP_001874496.1 PFAM: Integrase catalytic region; Resolvase helix-turn-helix domain protein; KEGG: ypp:YPDSF_2253 transposase for insertion sequence IS100 YP_001874497.1 KEGG: yps:YPTB3873 hypothetical protein YP_001874498.1 PFAM: restriction endonuclease; KEGG: ecv:APECO1_2075 methylated adenine and cytosine restriction protein YP_001874499.1 PFAM: protein of unknown function DUF45; KEGG: yps:YPTB3878 putative predicted metal-dependent hydrolase YP_001874500.1 KEGG: yps:YPTB3879 possible type I restriction enzyme (restriction subunit); TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases YP_001874501.1 KEGG: yps:YPTB3880 hypothetical protein YP_001874502.1 PFAM: restriction modification system DNA specificity domain; KEGG: yps:YPTB3881 possible restriction modification enzyme YP_001874503.1 TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase; KEGG: yps:YPTB3882 putative type I site-specific deoxyribonuclease LldI chain hs... YP_001874504.1 KEGG: yps:YPTB3883 hypothetical protein YP_001874505.1 KEGG: yps:YPTB3885 putative (AJ250469) putative SinR-like protein YP_001874506.1 PFAM: integrase family protein; KEGG: yps:YPTB3886 putative integrase YP_001874507.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: ypn:YPN_3681 AraC-family transcriptional regulatory protein YP_001874508.1 PFAM: inner-membrane translocator; KEGG: ypn:YPN_3682 sugar transport system permease protein YP_001874509.1 with XylFH is part of the high affinity xylose ABC transporter YP_001874510.1 periplasmic substrate-binding component of the ATP-dependent xylose transport system; high affinity YP_001874511.1 catalyzes the interconversion of D-xylose to D-xylulose YP_001874512.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: yps:YPTB3892 xylulose kinase YP_001874513.1 PFAM: Fimbrial protein; KEGG: ypg:YpAngola_A4163 hypothetical protein YP_001874514.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: ypp:YPDSF_3783 fimbrial chaperone YP_001874515.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: ypi:YpsIP31758_4106 fimbrial usher protein YP_001874516.1 PFAM: Fimbrial protein; KEGG: yps:YPTB3896 fimbrial protein YP_001874517.1 PFAM: acyltransferase 3; KEGG: yps:YPTB3897 hypothetical protein YP_001874518.1 KEGG: yps:YPTB3938 IS1661 DNA-binding protein YP_001874519.1 PFAM: Integrase catalytic region; KEGG: yps:YPTB3899 IS1661 transposase YP_001874520.1 catalyzes the formation of L-proline from L-ornithine YP_001874521.1 PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ypi:YpsIP31758_4146 putative threonine ammonia-lyase, catabolic YP_001874522.1 KEGG: yps:YPTB3902 hypothetical protein YP_001874523.1 PFAM: protein of unknown function DUF1375; KEGG: yps:YPTB3903 hypothetical protein YP_001874524.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_001874525.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_001874526.1 TIGRFAM: YidE/YbjL duplication; PFAM: TrkA-C domain protein; YidE/YbjL duplication domain protein; KEGG: ypi:YpsIP31758_4141 putative transport protein YidE YP_001874527.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_001874528.1 KEGG: yps:YPTB3908 hypothetical protein YP_001874529.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_001874530.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ypi:YpsIP31758_4137 2-ketogluconate reductase YP_001874531.1 KEGG: yps:YPTB3911 hypothetical protein YP_001874532.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: yps:YPTB3912 predicted outer membrane lipoprotein YP_001874534.1 PFAM: GCN5-related N-acetyltransferase; KEGG: yps:YPTB3913 hypothetical protein YP_001874535.1 TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase; KEGG: ypp:YPDSF_0021 DNA-3-methyladenine glycosylase YP_001874536.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001874537.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001874538.1 KEGG: ypn:YPN_2624 hypothetical protein YP_001874539.1 KEGG: ypi:YpsIP31758_4129 putative lipoprotein YP_001874540.1 KEGG: ypi:YpsIP31758_1513 hypothetical protein YP_001874541.1 TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: ypi:YpsIP31758_4128 PTS system, mannitol-specific EIICBA component YP_001874542.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: yps:YPTB3919 mannitol-1-phosphate 5-dehydrogenase YP_001874543.1 Acts as a repressor of the mtlAD operon YP_001874545.1 KEGG: ypi:YpsIP31758_4125 hypothetical protein YP_001874546.1 KEGG: ypi:YpsIP31758_4124 hypothetical protein YP_001874548.1 KEGG: yps:YPTB3923 hypothetical protein YP_001874549.1 PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; KEGG: ypi:YpsIP31758_4122 methyl-accepting chemotaxis protein YP_001874550.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_001874551.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_001874552.1 PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: yps:YPTB3927 formate dehydrogenase-O, major subunit (formate dehydrogenase... YP_001874553.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: yps:YPTB3927 formate dehydrogenase-O, major subunit (formate dehydrogenase... YP_001874554.1 TIGRFAM: formate dehydrogenase, beta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Formate dehydrogenase transmembrane domain protein; KEGG: ypi:YpsIP31758_4118 putative aerobic formate dehydrogenase, iron-sulfur subunit YP_001874555.1 cytochrome b556(FDO) component; heme containing YP_001874556.1 required for the formation of active formate dehydrogenase YP_001874557.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001874558.1 TIGRFAM: selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; KEGG: yps:YPTB3932 selenocysteinyl-tRNA-specific translation factor YP_001874559.1 KEGG: yps:YPTB3934 hypothetical protein YP_001874560.1 PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: ypn:YPN_0011 GntR-famly transcriptional regulator YP_001874561.1 PFAM: major facilitator superfamily MFS_1; KEGG: ypn:YPN_0010 membrane transport protein YP_001874562.1 KEGG: ypn:YPN_0009 hypothetical protein YP_001874563.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001874564.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_001874565.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_001874566.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_001874567.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_001874568.1 catalyzes the formation of asparagine from aspartate and ammonia YP_001874569.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001874570.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001874571.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001874572.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001874573.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_001874574.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001874575.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001874576.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001874577.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001874578.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001874579.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001874580.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001874581.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001874582.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_001874584.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001874585.1 KEGG: ypi:YpsIP31758_4172 hypothetical protein YP_001874586.1 TIGRFAM: phosphate ABC transporter, periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: ypi:YpsIP31758_4171 phosphate ABC transporter, phosphate-binding protein PstS YP_001874587.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001874588.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001874589.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001874590.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001874591.1 PFAM: protein of unknown function DUF583; KEGG: yps:YPTB3958 hypothetical protein YP_001874592.1 PFAM: extracellular solute-binding protein family 3; KEGG: ypn:YPN_3968 periplasmic solute-binding protein YP_001874593.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yps:YPTB3956 ABC amino acid transporter, permease subunit YP_001874594.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: yps:YPTB3955 ABC amino acid transporter, permease subunit YP_001874595.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_001874596.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: ypn:YPN_3964 xanthine/uracil permeases family protein YP_001874597.1 KEGG: yps:YPTB3952 hypothetical protein YP_001874598.1 KEGG: yps:YPTB3951 hypothetical protein YP_001874599.1 KEGG: ypi:YpsIP31758_4160 hypothetical protein YP_001874600.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_001874601.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001874602.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001874603.1 PFAM: protein of unknown function DUF37; KEGG: yps:YPTB3947 hypothetical protein YP_001874604.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001874605.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001874606.1 KEGG: ypm:YP_4006 hypothetical protein YP_001874607.1 TIGRFAM: type III secretion system chaperone, YscB family; PFAM: Tir chaperone family protein; KEGG: ypa:YPA_CD0013 hypothetical protein YP_001874608.1 TIGRFAM: type III secretion outer membrane pore, YscC/HrcC family; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: ypa:YPA_CD0012 type III secretion protein YP_001874609.1 TIGRFAM: type III secretion apparatus protein, YscD/HrpQ family; PFAM: Forkhead-associated protein; KEGG: ypa:YPA_CD0011 type III secretion protein YP_001874610.1 TIGRFAM: type III secretion system protein, YseE family; PFAM: Protein of unknown function DUF1895; KEGG: yps:pYV0081 YscE; putative type III secretion protein YP_001874611.1 TIGRFAM: type III secretion system needle protein; KEGG: ypa:YPA_CD0010 type III secretion protein YP_001874612.1 TIGRFAM: type III secretion protein, YscG family; PFAM: Type III secretion system YscG family protein; KEGG: yps:pYV0083 YscG; putative type III secretion protein YP_001874613.1 TIGRFAM: type III secretion effector, YopR family; PFAM: Type III secretion system effector YopR family protein; KEGG: yps:pYV0084 YscH, YopR, LcrP; putative type III secretion protein YP_001874614.1 TIGRFAM: type III secretion apparatus protein, YscI/HrpB family; PFAM: type III secretion system YscI/HrpB domain protein; KEGG: ypa:YPA_CD0007 type III secretion protein YP_001874615.1 TIGRFAM: type III secretion apparatus lipoprotein, YscJ/HrcJ family; PFAM: secretory protein YscJ/FliF family protein; KEGG: ypa:YPA_CD0006 type III secretion lipoprotein YP_001874616.1 PFAM: YOP protein translocation K family protein; KEGG: ypa:YPA_CD0005 type III secretion protein YP_001874617.1 TIGRFAM: type III secretion apparatus protein, HrpE/YscL family; PFAM: flagellar assembly protein FliH; KEGG: ypa:YPA_CD0004 type III secretion protein YP_001874618.1 PFAM: Protein-tyrosine phosphatase YopH; KEGG: yps:pYV0089 YscM, LcrQ; putative type III secretion regulatory YP_001874619.1 PFAM: transposase IS3/IS911 family protein; KEGG: yps:pYV0090 putative transposase YP_001874620.1 KEGG: yps:pYV0091 putative transposase YP_001874621.1 PFAM: tyrosine specific protein phosphatase; Protein-tyrosine phosphatase YopH; SMART: Protein-tyrosine phosphatase, catalytic; KEGG: yps:pYV0094 YopH; putative protein-tyrosine phosphatase Yop effector YP_001874622.1 PFAM: Integrase catalytic region; KEGG: yps:pYV0095 putative transposase YP_001874623.1 PFAM: peptidase C55; KEGG: yps:pYV0098 YopP, YopJ; putative targeted effector protein YP_001874624.1 SMART: serine/threonine protein kinase; KEGG: yps:pYV0001 YpkA; putative targeted effector protein kinase YP_001874625.1 KEGG: yps:pYV0002 hypothetical protein YP_001874626.1 KEGG: spe:Spro_0361 transposase IS3/IS911 family protein YP_001874627.1 KEGG: yps:pYV0003 putative transposase remnant YP_001874628.1 KEGG: yps:pYV0004 hypothetical protein YP_001874629.1 KEGG: ypm:YP_pCD09 hypothetical protein YP_001874630.1 RepA YP_001874631.1 KEGG: yps:pYV0007 RepB, repA2, CopB; putative replication transcriptional regulator YP_001874632.1 SMART: phospholipase D/Transphosphatidylase; KEGG: ypp:YPDSF_3938 phospholipase D/transphosphatidylase YP_001874633.1 KEGG: ypa:YPA_CD0070 transposase remnant YP_001874634.1 KEGG: yps:pYV0035 hypothetical protein YP_001874635.1 PFAM: transposase IS3/IS911 family protein; KEGG: ypa:YPA_CD0065 hypothetical protein YP_001874636.1 KEGG: ypa:YPA_CD0064 hypothetical protein YP_001874637.1 KEGG: yps:pYV0009 hyothetical protein YP_001874638.1 PFAM: YadA domain protein; Haemagluttinin domain protein; Hep_Hag repeat-containing protein; KEGG: yps:pYV0013 hypothetical protein YP_001874639.1 KEGG: ypa:YPA_CD0060 hypothetical protein YP_001874640.1 PFAM: transposase Tn3 family protein; KEGG: ypm:YP_pCD93 putative transposase YP_001874641.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: ypa:YPA_CD0059 resolvase YP_001874642.1 KEGG: ypg:YpAngola_B0091 hypothetical protein YP_001874643.1 KEGG: ypg:YpAngola_B0092 hypothetical protein YP_001874644.1 PFAM: transposase IS3/IS911 family protein; KEGG: ypn:YPN_3423 helix-turn-helix, fis-type YP_001874645.1 PFAM: Integrase catalytic region; KEGG: yps:pYV0019 putative transposase YP_001874646.1 PFAM: Tir chaperone family protein; KEGG: yps:pYV0020 SycH; putative YopH targeting protein YP_001874647.1 PFAM: IstB domain protein ATP-binding protein; KEGG: ype:YPCD1.96c putative transposase YP_001874648.1 PFAM: Integrase catalytic region; KEGG: yps:pYV0022 putative transposase YP_001874649.1 KEGG: ypm:YP_3786 hypothetical protein YP_001874650.1 KEGG: ypa:YPA_CD0053 hypothetical protein YP_001874651.1 PFAM: Tir chaperone family protein; KEGG: yps:pYV0024 SycE, YerA; putative YopE chaperone YP_001874652.1 PFAM: virulence determinant YopE; KEGG: yps:pYV0025 putative outer membrane virulence protein YP_001874653.1 PFAM: plasmid stabilization system; KEGG: yps:pYV0026 hypothetical protein YP_001874654.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: yps:pYV0027 hypothetical protein YP_001874655.1 KEGG: yps:pYV0028 putative transposase remnant YP_001874656.1 KEGG: rno:691992 glycoprotein 1b, alpha polypeptide YP_001874657.1 SopB YP_001874658.1 PFAM: regulatory protein MerR; Cobyrinic acid ac-diamide synthase; KEGG: ypa:YPA_CD0048 plasmid partitioning transcription repressor YP_001874659.1 KEGG: spe:Spro_0386 site-specific recombinase, phage integrase family YP_001874660.1 KEGG: ypa:YPA_CD0070 transposase remnant YP_001874661.1 KEGG: ypa:YPA_CD0046 hypothetical protein YP_001874662.1 PFAM: transposase IS3/IS911 family protein; KEGG: ypa:YPA_CD0065 hypothetical protein YP_001874663.1 PFAM: TraT complement resistance family protein; KEGG: ypa:YPA_CD0044 conjugative transfer surface exclusion protein YP_001874664.1 KEGG: yps:pYV0040 yop targeting protein YopK, YopQ YP_001874665.1 TIGRFAM: cysteine protease domain protein, YopT-type; PFAM: peptidase C58 Yersinia/Haemophilus virulence surface antigen; KEGG: yps:pYV0041 yop targeted effector YopT YP_001874666.1 PFAM: Tir chaperone family protein; KEGG: yps:pYV0042 YopT chaperone YP_001874667.1 KEGG: ypg:YpAngola_B0018 hypothetical protein YP_001874668.1 KEGG: yps:pYV0044 hypothetical protein YP_001874669.1 KEGG: yps:pYV0046 putative transposase remnant YP_001874670.1 KEGG: yps:pYV0047 YopM; putative targeted effector protein YP_001874671.1 KEGG: yps:pYV0049 hypothetical protein YP_001874672.1 PFAM: transposase mutator type; KEGG: yps:YPTB3311 putative transposase YP_001874673.1 PFAM: YopD family protein; KEGG: yps:pYV0054 YopD; putative Yop negative regulation/targeting component YP_001874674.1 PFAM: secretion system effector C (SseC) family protein; KEGG: yps:pYV0055 YopB; putative Yop targeting protein YP_001874675.1 TIGRFAM: type III secretion low calcium response chaperone LcrH/SycD; KEGG: yen:YEP0014 YopB/D chaperone/regulatory protein YP_001874676.1 PFAM: low calcium response V antigen; KEGG: yps:pYV0057 LcrV; putative V antigen, antihost protein/regulator YP_001874677.1 TIGRFAM: type III secretion protein LcrG; PFAM: LcrG family protein; KEGG: yps:pYV0058 LcrG; putative Yop regulator YP_001874678.1 TIGRFAM: type III secretion system regulator LcrR; PFAM: Type III secretion system regulator LcrR; KEGG: yps:pYV0059 LcrR; hypothetical protein LcrR YP_001874679.1 TIGRFAM: type III secretion protein, HrcV family; PFAM: type III secretion FHIPEP protein; KEGG: ypa:YPA_CD0028 membrane-bound Yop protein YP_001874680.1 KEGG: ypa:YPA_CD0027 type III secretion protein YP_001874681.1 TIGRFAM: type III secretion protein, YscX family; PFAM: type III secretion system YscX family protein; KEGG: ypa:YPA_CD0026 type III secretion protein YP_001874682.1 TIGRFAM: type III secretion chaperone SycN; KEGG: ypa:YPA_CD0025 type III secretion protein YP_001874683.1 TIGRFAM: type III secretion effector delivery regulator, TyeA family; PFAM: TyeA domain protein; KEGG: yen:YEP0022 type III secretion system protein YP_001874684.1 TIGRFAM: type III secretion regulator YopN/LcrE/InvE/MxiC; PFAM: Hypersensitivity response secretion HrpJ domain protein; KEGG: yps:pYV0065 YopN, LcrE; putative membrane-bound Yop targeting protein YP_001874685.1 KEGG: ypa:YPA_CD0022 Yop secretion ATP synthase; TIGRFAM: ATPase, FliI/YscN family; type III secretion apparatus H+-transporting two-sector ATPase; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase YP_001874686.1 PFAM: type III secretion YscO fmaily protein; KEGG: yps:pYV0068 YscO; putative type III secretion protein YP_001874687.1 TIGRFAM: type III secretion system needle length determinant; PFAM: Type III secretion system needle length determinant family protein; KEGG: yps:pYV0069 YscP; putative type III secretion protein YP_001874688.1 TIGRFAM: type III secretion system apparatus protein YscQ/HrcQ; PFAM: surface presentation of antigens (SPOA) protein; KEGG: yps:pYV0070 type III secretion system protein YP_001874689.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_001874690.1 TIGRFAM: type III secretion protein, HrpO family; PFAM: export protein FliQ family 3; KEGG: ypa:YPA_CD0017 type III secretion protein YP_001874691.1 TIGRFAM: type III secretion protein SpaR/YscT/HrcT; PFAM: type III secretion system inner membrane R protein; KEGG: ypa:YPA_CD0016 type III secretion protein YP_001874692.1 TIGRFAM: type III secretion protein, YscU/HrpY family; PFAM: type III secretion exporter; KEGG: ypa:YPA_CD0015 type III secretion protein YP_001874693.1 TIGRFAM: type III secretion system chaperone YscW; PFAM: Type III secretion system chaperone YscW; KEGG: yps:pYV0075 VirG; putative Yop targeting lipoprotein