-- dump date   	20140620_141711
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
502801000001	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
502801000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
502801000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801000004	Walker A motif; other site
502801000005	ATP binding site [chemical binding]; other site
502801000006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
502801000007	Walker B motif; other site
502801000008	arginine finger; other site
502801000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
502801000010	DnaA box-binding interface [nucleotide binding]; other site
502801000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
502801000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
502801000013	putative DNA binding surface [nucleotide binding]; other site
502801000014	dimer interface [polypeptide binding]; other site
502801000015	beta-clamp/clamp loader binding surface; other site
502801000016	beta-clamp/translesion DNA polymerase binding surface; other site
502801000017	recF protein; Region: recf; TIGR00611
502801000018	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801000019	Walker A/P-loop; other site
502801000020	ATP binding site [chemical binding]; other site
502801000021	Q-loop/lid; other site
502801000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801000023	ABC transporter signature motif; other site
502801000024	Walker B; other site
502801000025	D-loop; other site
502801000026	H-loop/switch region; other site
502801000027	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
502801000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801000029	Mg2+ binding site [ion binding]; other site
502801000030	G-X-G motif; other site
502801000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
502801000032	anchoring element; other site
502801000033	dimer interface [polypeptide binding]; other site
502801000034	ATP binding site [chemical binding]; other site
502801000035	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
502801000036	active site
502801000037	putative metal-binding site [ion binding]; other site
502801000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
502801000039	sugar phosphate phosphatase; Provisional; Region: PRK10513
502801000040	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801000041	active site
502801000042	motif I; other site
502801000043	motif II; other site
502801000044	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801000045	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
502801000046	Helix-turn-helix domain; Region: HTH_28; pfam13518
502801000047	Helix-turn-helix domain; Region: HTH_28; pfam13518
502801000048	putative transposase OrfB; Reviewed; Region: PHA02517
502801000049	HTH-like domain; Region: HTH_21; pfam13276
502801000050	Integrase core domain; Region: rve; pfam00665
502801000051	Integrase core domain; Region: rve_2; pfam13333
502801000052	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
502801000053	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801000054	putative substrate translocation pore; other site
502801000055	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
502801000056	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
502801000057	MULE transposase domain; Region: MULE; pfam10551
502801000058	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
502801000059	Walker A motif; other site
502801000060	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
502801000061	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
502801000062	GTP binding site; other site
502801000063	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3084
502801000064	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
502801000065	serine/threonine protein kinase; Provisional; Region: PRK11768
502801000066	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
502801000067	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
502801000068	catalytic residues [active]
502801000069	hinge region; other site
502801000070	alpha helical domain; other site
502801000071	DNA polymerase I; Provisional; Region: PRK05755
502801000072	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
502801000073	active site
502801000074	metal binding site 1 [ion binding]; metal-binding site
502801000075	putative 5' ssDNA interaction site; other site
502801000076	metal binding site 3; metal-binding site
502801000077	metal binding site 2 [ion binding]; metal-binding site
502801000078	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
502801000079	putative DNA binding site [nucleotide binding]; other site
502801000080	putative metal binding site [ion binding]; other site
502801000081	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
502801000082	active site
502801000083	catalytic site [active]
502801000084	substrate binding site [chemical binding]; other site
502801000085	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
502801000086	active site
502801000087	DNA binding site [nucleotide binding]
502801000088	catalytic site [active]
502801000089	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
502801000090	G1 box; other site
502801000091	GTP/Mg2+ binding site [chemical binding]; other site
502801000092	Switch I region; other site
502801000093	G2 box; other site
502801000094	G3 box; other site
502801000095	Switch II region; other site
502801000096	G4 box; other site
502801000097	G5 box; other site
502801000098	Der GTPase activator; Provisional; Region: PRK05244
502801000099	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
502801000100	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801000101	FeS/SAM binding site; other site
502801000102	HemN C-terminal domain; Region: HemN_C; pfam06969
502801000103	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
502801000104	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801000105	active site
502801000106	phosphorylation site [posttranslational modification]
502801000107	intermolecular recognition site; other site
502801000108	dimerization interface [polypeptide binding]; other site
502801000109	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801000110	Walker A motif; other site
502801000111	ATP binding site [chemical binding]; other site
502801000112	Walker B motif; other site
502801000113	arginine finger; other site
502801000114	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
502801000115	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
502801000116	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
502801000117	dimer interface [polypeptide binding]; other site
502801000118	phosphorylation site [posttranslational modification]
502801000119	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801000120	ATP binding site [chemical binding]; other site
502801000121	Mg2+ binding site [ion binding]; other site
502801000122	G-X-G motif; other site
502801000123	glutamine synthetase; Provisional; Region: glnA; PRK09469
502801000124	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
502801000125	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
502801000126	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
502801000127	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
502801000128	G1 box; other site
502801000129	putative GEF interaction site [polypeptide binding]; other site
502801000130	GTP/Mg2+ binding site [chemical binding]; other site
502801000131	Switch I region; other site
502801000132	G2 box; other site
502801000133	G3 box; other site
502801000134	Switch II region; other site
502801000135	G4 box; other site
502801000136	G5 box; other site
502801000137	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
502801000138	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
502801000139	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
502801000140	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801000141	motif II; other site
502801000142	hypothetical protein; Reviewed; Region: PRK01637
502801000143	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
502801000144	putative active site [active]
502801000145	dimerization interface [polypeptide binding]; other site
502801000146	putative tRNAtyr binding site [nucleotide binding]; other site
502801000147	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
502801000148	Coenzyme A binding pocket [chemical binding]; other site
502801000149	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
502801000150	AsmA family; Region: AsmA; pfam05170
502801000151	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
502801000152	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
502801000153	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
502801000154	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
502801000155	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
502801000156	generic binding surface II; other site
502801000157	ssDNA binding site; other site
502801000158	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
502801000159	ATP binding site [chemical binding]; other site
502801000160	putative Mg++ binding site [ion binding]; other site
502801000161	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801000162	nucleotide binding region [chemical binding]; other site
502801000163	ATP-binding site [chemical binding]; other site
502801000164	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
502801000165	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
502801000166	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
502801000167	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
502801000168	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
502801000169	Zn2+ binding site [ion binding]; other site
502801000170	Mg2+ binding site [ion binding]; other site
502801000171	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
502801000172	synthetase active site [active]
502801000173	NTP binding site [chemical binding]; other site
502801000174	metal binding site [ion binding]; metal-binding site
502801000175	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
502801000176	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
502801000177	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
502801000178	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
502801000179	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
502801000180	catalytic site [active]
502801000181	G-X2-G-X-G-K; other site
502801000182	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
502801000183	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
502801000184	nucleotide binding pocket [chemical binding]; other site
502801000185	K-X-D-G motif; other site
502801000186	catalytic site [active]
502801000187	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
502801000188	Predicted membrane protein [Function unknown]; Region: COG2860
502801000189	UPF0126 domain; Region: UPF0126; pfam03458
502801000190	UPF0126 domain; Region: UPF0126; pfam03458
502801000191	hypothetical protein; Provisional; Region: PRK11820
502801000192	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
502801000193	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
502801000194	ribonuclease PH; Reviewed; Region: rph; PRK00173
502801000195	Ribonuclease PH; Region: RNase_PH_bact; cd11362
502801000196	hexamer interface [polypeptide binding]; other site
502801000197	active site
502801000198	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
502801000199	active site
502801000200	division inhibitor protein; Provisional; Region: slmA; PRK09480
502801000201	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
502801000202	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
502801000203	trimer interface [polypeptide binding]; other site
502801000204	active site
502801000205	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
502801000206	Flavoprotein; Region: Flavoprotein; pfam02441
502801000207	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
502801000208	hypothetical protein; Reviewed; Region: PRK00024
502801000209	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
502801000210	MPN+ (JAMM) motif; other site
502801000211	Zinc-binding site [ion binding]; other site
502801000212	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
502801000213	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
502801000214	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
502801000215	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
502801000216	DNA binding site [nucleotide binding]
502801000217	catalytic residue [active]
502801000218	H2TH interface [polypeptide binding]; other site
502801000219	putative catalytic residues [active]
502801000220	turnover-facilitating residue; other site
502801000221	intercalation triad [nucleotide binding]; other site
502801000222	8OG recognition residue [nucleotide binding]; other site
502801000223	putative reading head residues; other site
502801000224	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
502801000225	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
502801000226	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
502801000227	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
502801000228	active site
502801000229	(T/H)XGH motif; other site
502801000230	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
502801000231	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
502801000232	putative metal binding site; other site
502801000233	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
502801000234	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
502801000235	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
502801000236	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
502801000237	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
502801000238	putative active site [active]
502801000239	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
502801000240	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
502801000241	putative active site [active]
502801000242	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
502801000243	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
502801000244	NADP binding site [chemical binding]; other site
502801000245	homopentamer interface [polypeptide binding]; other site
502801000246	substrate binding site [chemical binding]; other site
502801000247	active site
502801000248	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
502801000249	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
502801000250	substrate-cofactor binding pocket; other site
502801000251	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801000252	catalytic residue [active]
502801000253	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
502801000254	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
502801000255	NAD(P) binding site [chemical binding]; other site
502801000256	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
502801000257	NodB motif; other site
502801000258	putative active site [active]
502801000259	putative catalytic site [active]
502801000260	Zn binding site [ion binding]; other site
502801000261	AmiB activator; Provisional; Region: PRK11637
502801000262	Peptidase family M23; Region: Peptidase_M23; pfam01551
502801000263	phosphoglyceromutase; Provisional; Region: PRK05434
502801000264	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
502801000265	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
502801000266	active site residue [active]
502801000267	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
502801000268	GSH binding site [chemical binding]; other site
502801000269	catalytic residues [active]
502801000270	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
502801000271	SecA binding site; other site
502801000272	Preprotein binding site; other site
502801000273	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
502801000274	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
502801000275	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
502801000276	serine acetyltransferase; Provisional; Region: cysE; PRK11132
502801000277	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
502801000278	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
502801000279	trimer interface [polypeptide binding]; other site
502801000280	active site
502801000281	substrate binding site [chemical binding]; other site
502801000282	CoA binding site [chemical binding]; other site
502801000283	putative rRNA methylase; Provisional; Region: PRK10358
502801000284	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
502801000285	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
502801000286	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801000287	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801000288	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
502801000289	DNA binding site [nucleotide binding]
502801000290	active site
502801000291	two-component sensor protein; Provisional; Region: cpxA; PRK09470
502801000292	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
502801000293	dimerization interface [polypeptide binding]; other site
502801000294	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801000295	dimer interface [polypeptide binding]; other site
502801000296	phosphorylation site [posttranslational modification]
502801000297	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801000298	ATP binding site [chemical binding]; other site
502801000299	Mg2+ binding site [ion binding]; other site
502801000300	G-X-G motif; other site
502801000301	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
502801000302	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801000303	active site
502801000304	phosphorylation site [posttranslational modification]
502801000305	intermolecular recognition site; other site
502801000306	dimerization interface [polypeptide binding]; other site
502801000307	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801000308	DNA binding site [nucleotide binding]
502801000309	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
502801000310	dimer interface [polypeptide binding]; other site
502801000311	Uncharacterized conserved protein [Function unknown]; Region: COG5464
502801000312	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
502801000313	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; cl17722
502801000314	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
502801000315	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
502801000316	6-phosphofructokinase; Provisional; Region: PRK03202
502801000317	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
502801000318	active site
502801000319	ADP/pyrophosphate binding site [chemical binding]; other site
502801000320	dimerization interface [polypeptide binding]; other site
502801000321	allosteric effector site; other site
502801000322	fructose-1,6-bisphosphate binding site; other site
502801000323	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801000324	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
502801000325	substrate binding pocket [chemical binding]; other site
502801000326	membrane-bound complex binding site; other site
502801000327	hinge residues; other site
502801000328	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
502801000329	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
502801000330	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
502801000331	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
502801000332	transmembrane helices; other site
502801000333	hypothetical protein; Validated; Region: PRK06201
502801000334	hypothetical protein; Provisional; Region: PRK09262
502801000335	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
502801000336	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801000337	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801000338	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801000339	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801000340	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
502801000341	dimerization interface [polypeptide binding]; other site
502801000342	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
502801000343	triosephosphate isomerase; Provisional; Region: PRK14567
502801000344	substrate binding site [chemical binding]; other site
502801000345	dimer interface [polypeptide binding]; other site
502801000346	catalytic triad [active]
502801000347	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
502801000348	Predicted membrane protein [Function unknown]; Region: COG3152
502801000349	ferredoxin-NADP reductase; Provisional; Region: PRK10926
502801000350	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
502801000351	FAD binding pocket [chemical binding]; other site
502801000352	FAD binding motif [chemical binding]; other site
502801000353	phosphate binding motif [ion binding]; other site
502801000354	beta-alpha-beta structure motif; other site
502801000355	NAD binding pocket [chemical binding]; other site
502801000356	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
502801000357	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
502801000358	putative active site [active]
502801000359	glycerol kinase; Provisional; Region: glpK; PRK00047
502801000360	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
502801000361	N- and C-terminal domain interface [polypeptide binding]; other site
502801000362	active site
502801000363	MgATP binding site [chemical binding]; other site
502801000364	catalytic site [active]
502801000365	metal binding site [ion binding]; metal-binding site
502801000366	glycerol binding site [chemical binding]; other site
502801000367	homotetramer interface [polypeptide binding]; other site
502801000368	homodimer interface [polypeptide binding]; other site
502801000369	FBP binding site [chemical binding]; other site
502801000370	protein IIAGlc interface [polypeptide binding]; other site
502801000371	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
502801000372	amphipathic channel; other site
502801000373	Asn-Pro-Ala signature motifs; other site
502801000374	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3074
502801000375	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
502801000376	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419
502801000377	putative active site [active]
502801000378	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801000379	ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246
502801000380	Walker A/P-loop; other site
502801000381	ATP binding site [chemical binding]; other site
502801000382	Q-loop/lid; other site
502801000383	ABC transporter signature motif; other site
502801000384	Walker B; other site
502801000385	D-loop; other site
502801000386	H-loop/switch region; other site
502801000387	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
502801000388	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801000389	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801000390	Protein of unknown function (DUF4232); Region: DUF4232; pfam14016
502801000391	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
502801000392	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
502801000393	UbiA prenyltransferase family; Region: UbiA; pfam01040
502801000394	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
502801000395	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801000396	Walker A motif; other site
502801000397	ATP binding site [chemical binding]; other site
502801000398	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
502801000399	Walker B motif; other site
502801000400	arginine finger; other site
502801000401	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
502801000402	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
502801000403	active site
502801000404	HslU subunit interaction site [polypeptide binding]; other site
502801000405	cell division protein FtsN; Provisional; Region: PRK12757
502801000406	Sporulation related domain; Region: SPOR; cl10051
502801000407	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801000408	DNA binding site [nucleotide binding]
502801000409	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
502801000410	domain linker motif; other site
502801000411	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
502801000412	dimerization interface [polypeptide binding]; other site
502801000413	ligand binding site [chemical binding]; other site
502801000414	primosome assembly protein PriA; Validated; Region: PRK05580
502801000415	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
502801000416	ATP binding site [chemical binding]; other site
502801000417	putative Mg++ binding site [ion binding]; other site
502801000418	helicase superfamily c-terminal domain; Region: HELICc; smart00490
502801000419	ATP-binding site [chemical binding]; other site
502801000420	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
502801000421	Predicted membrane protein [Function unknown]; Region: COG4682
502801000422	yiaA/B two helix domain; Region: YiaAB; pfam05360
502801000423	yiaA/B two helix domain; Region: YiaAB; pfam05360
502801000424	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
502801000425	dimerization interface [polypeptide binding]; other site
502801000426	DNA binding site [nucleotide binding]
502801000427	corepressor binding sites; other site
502801000428	cystathionine gamma-synthase; Provisional; Region: PRK08045
502801000429	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
502801000430	homodimer interface [polypeptide binding]; other site
502801000431	substrate-cofactor binding pocket; other site
502801000432	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801000433	catalytic residue [active]
502801000434	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
502801000435	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
502801000436	putative catalytic residues [active]
502801000437	putative nucleotide binding site [chemical binding]; other site
502801000438	putative aspartate binding site [chemical binding]; other site
502801000439	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
502801000440	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
502801000441	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
502801000442	FAD binding site [chemical binding]; other site
502801000443	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
502801000444	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
502801000445	acetylornithine deacetylase; Provisional; Region: PRK05111
502801000446	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
502801000447	metal binding site [ion binding]; metal-binding site
502801000448	putative dimer interface [polypeptide binding]; other site
502801000449	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
502801000450	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
502801000451	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
502801000452	nucleotide binding site [chemical binding]; other site
502801000453	N-acetyl-L-glutamate binding site [chemical binding]; other site
502801000454	argininosuccinate lyase; Provisional; Region: PRK04833
502801000455	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
502801000456	active sites [active]
502801000457	tetramer interface [polypeptide binding]; other site
502801000458	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
502801000459	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801000460	N-terminal plug; other site
502801000461	ligand-binding site [chemical binding]; other site
502801000462	Heme-binding protein A (HasA); Region: HasA; pfam06438
502801000463	ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only]; Region: ArpD; COG4618
502801000464	ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246
502801000465	Walker A/P-loop; other site
502801000466	ATP binding site [chemical binding]; other site
502801000467	Q-loop/lid; other site
502801000468	ABC transporter signature motif; other site
502801000469	Walker B; other site
502801000470	D-loop; other site
502801000471	H-loop/switch region; other site
502801000472	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
502801000473	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801000474	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801000475	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
502801000476	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
502801000477	dihydrolipoamide dehydrogenase; Validated; Region: PRK06292
502801000478	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
502801000479	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
502801000480	Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; Region: PRX5_like; cd03013
502801000481	catalytic triad [active]
502801000482	dimer interface [polypeptide binding]; other site
502801000483	Glutaredoxin (GRX) family, PRX5 hybrid subfamily; composed of hybrid proteins containing peroxiredoxin (PRX) and GRX domains, which is found in some pathogenic bacteria and cyanobacteria. PRXs are thiol-specific antioxidant (TSA) proteins that confer a...; Region: GRX_hybridPRX5; cd03029
502801000484	GSH binding site [chemical binding]; other site
502801000485	catalytic residues [active]
502801000486	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
502801000487	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801000488	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
502801000489	dimerization interface [polypeptide binding]; other site
502801000490	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
502801000491	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
502801000492	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
502801000493	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
502801000494	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
502801000495	hypothetical protein; Provisional; Region: PRK11056
502801000496	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
502801000497	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
502801000498	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801000499	N-terminal plug; other site
502801000500	ligand-binding site [chemical binding]; other site
502801000501	glutamate racemase; Provisional; Region: PRK00865
502801000502	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
502801000503	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
502801000504	putative ligand binding site [chemical binding]; other site
502801000505	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801000506	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801000507	Walker A/P-loop; other site
502801000508	ATP binding site [chemical binding]; other site
502801000509	Q-loop/lid; other site
502801000510	ABC transporter signature motif; other site
502801000511	Walker B; other site
502801000512	D-loop; other site
502801000513	H-loop/switch region; other site
502801000514	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801000515	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801000516	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801000517	TM-ABC transporter signature motif; other site
502801000518	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801000519	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801000520	TM-ABC transporter signature motif; other site
502801000521	transcriptional regulator HdfR; Provisional; Region: PRK03601
502801000522	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801000523	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
502801000524	dimerization interface [polypeptide binding]; other site
502801000525	hypothetical protein; Provisional; Region: PRK11027
502801000526	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
502801000527	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
502801000528	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
502801000529	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
502801000530	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
502801000531	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
502801000532	PYR/PP interface [polypeptide binding]; other site
502801000533	dimer interface [polypeptide binding]; other site
502801000534	TPP binding site [chemical binding]; other site
502801000535	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
502801000536	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
502801000537	TPP-binding site [chemical binding]; other site
502801000538	dimer interface [polypeptide binding]; other site
502801000539	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
502801000540	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
502801000541	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
502801000542	homodimer interface [polypeptide binding]; other site
502801000543	substrate-cofactor binding pocket; other site
502801000544	catalytic residue [active]
502801000545	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
502801000546	threonine dehydratase; Reviewed; Region: PRK09224
502801000547	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
502801000548	tetramer interface [polypeptide binding]; other site
502801000549	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801000550	catalytic residue [active]
502801000551	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
502801000552	putative Ile/Val binding site [chemical binding]; other site
502801000553	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
502801000554	putative Ile/Val binding site [chemical binding]; other site
502801000555	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
502801000556	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
502801000557	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
502801000558	conserved hypothetical protein; Region: TIGR03034
502801000559	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801000560	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
502801000561	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
502801000562	putative dimerization interface [polypeptide binding]; other site
502801000563	ketol-acid reductoisomerase; Validated; Region: PRK05225
502801000564	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
502801000565	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
502801000566	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
502801000567	S-type Pyocin; Region: Pyocin_S; pfam06958
502801000568	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
502801000569	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
502801000570	active site
502801000571	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
502801000572	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
502801000573	active site
502801000574	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
502801000575	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
502801000576	Cloacin immunity protein; Region: Cloacin_immun; pfam03513
502801000577	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
502801000578	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801000579	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
502801000580	Fimbrial protein; Region: Fimbrial; cl01416
502801000581	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
502801000582	PapC N-terminal domain; Region: PapC_N; pfam13954
502801000583	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
502801000584	PapC C-terminal domain; Region: PapC_C; pfam13953
502801000585	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
502801000586	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801000587	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
502801000588	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
502801000589	Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823
502801000590	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
502801000591	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
502801000592	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
502801000593	Part of AAA domain; Region: AAA_19; pfam13245
502801000594	Family description; Region: UvrD_C_2; pfam13538
502801000595	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
502801000596	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
502801000597	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
502801000598	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
502801000599	ATP binding site [chemical binding]; other site
502801000600	Mg++ binding site [ion binding]; other site
502801000601	motif III; other site
502801000602	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801000603	nucleotide binding region [chemical binding]; other site
502801000604	ATP-binding site [chemical binding]; other site
502801000605	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
502801000606	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
502801000607	catalytic residues [active]
502801000608	transcription termination factor Rho; Provisional; Region: rho; PRK09376
502801000609	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
502801000610	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
502801000611	RNA binding site [nucleotide binding]; other site
502801000612	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
502801000613	multimer interface [polypeptide binding]; other site
502801000614	Walker A motif; other site
502801000615	ATP binding site [chemical binding]; other site
502801000616	Walker B motif; other site
502801000617	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
502801000618	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
502801000619	Mg++ binding site [ion binding]; other site
502801000620	putative catalytic motif [active]
502801000621	substrate binding site [chemical binding]; other site
502801000622	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
502801000623	Chain length determinant protein; Region: Wzz; cl15801
502801000624	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
502801000625	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
502801000626	active site
502801000627	homodimer interface [polypeptide binding]; other site
502801000628	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
502801000629	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
502801000630	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
502801000631	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
502801000632	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
502801000633	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
502801000634	NAD binding site [chemical binding]; other site
502801000635	substrate binding site [chemical binding]; other site
502801000636	homodimer interface [polypeptide binding]; other site
502801000637	active site
502801000638	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
502801000639	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
502801000640	substrate binding site; other site
502801000641	tetramer interface; other site
502801000642	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
502801000643	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
502801000644	Coenzyme A binding pocket [chemical binding]; other site
502801000645	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
502801000646	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
502801000647	inhibitor-cofactor binding pocket; inhibition site
502801000648	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801000649	catalytic residue [active]
502801000650	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
502801000651	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
502801000652	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
502801000653	putative common antigen polymerase; Provisional; Region: PRK02975
502801000654	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
502801000655	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
502801000656	putative transport protein YifK; Provisional; Region: PRK10746
502801000657	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
502801000658	HemY protein N-terminus; Region: HemY_N; pfam07219
502801000659	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
502801000660	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
502801000661	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
502801000662	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
502801000663	active site
502801000664	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
502801000665	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
502801000666	domain interfaces; other site
502801000667	active site
502801000668	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
502801000669	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
502801000670	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
502801000671	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
502801000672	MULE transposase domain; Region: MULE; pfam10551
502801000673	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
502801000674	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
502801000675	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
502801000676	putative iron binding site [ion binding]; other site
502801000677	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
502801000678	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
502801000679	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
502801000680	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
502801000681	hypothetical protein; Provisional; Region: PRK10963
502801000682	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
502801000683	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
502801000684	active site
502801000685	Int/Topo IB signature motif; other site
502801000686	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
502801000687	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801000688	motif II; other site
502801000689	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
502801000690	Part of AAA domain; Region: AAA_19; pfam13245
502801000691	Family description; Region: UvrD_C_2; pfam13538
502801000692	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
502801000693	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
502801000694	Uncharacterized conserved protein [Function unknown]; Region: COG5441
502801000695	Uncharacterized protein family (UPF0261); Region: UPF0261; pfam06792
502801000696	TIM-barrel signal transduction protein; Region: TIM-br_sig_trns; pfam09370
502801000697	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
502801000698	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
502801000699	Cl binding site [ion binding]; other site
502801000700	oligomer interface [polypeptide binding]; other site
502801000701	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
502801000702	EamA-like transporter family; Region: EamA; cl17759
502801000703	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
502801000704	CoenzymeA binding site [chemical binding]; other site
502801000705	subunit interaction site [polypeptide binding]; other site
502801000706	PHB binding site; other site
502801000707	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
502801000708	substrate binding site [chemical binding]; other site
502801000709	dimerization interface [polypeptide binding]; other site
502801000710	active site
502801000711	calcium binding site [ion binding]; other site
502801000712	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
502801000713	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
502801000714	ATP binding site [chemical binding]; other site
502801000715	putative Mg++ binding site [ion binding]; other site
502801000716	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801000717	nucleotide binding region [chemical binding]; other site
502801000718	ATP-binding site [chemical binding]; other site
502801000719	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
502801000720	HRDC domain; Region: HRDC; pfam00570
502801000721	threonine efflux system; Provisional; Region: PRK10229
502801000722	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
502801000723	lysophospholipase L2; Provisional; Region: PRK10749
502801000724	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
502801000725	putative hydrolase; Provisional; Region: PRK10976
502801000726	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801000727	active site
502801000728	motif I; other site
502801000729	motif II; other site
502801000730	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
502801000731	Viral enhancin protein; Region: Enhancin; pfam03272
502801000732	Viral enhancin protein; Region: Enhancin; pfam03272
502801000733	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
502801000734	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
502801000735	active site
502801000736	catalytic site [active]
502801000737	metal binding site [ion binding]; metal-binding site
502801000738	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
502801000739	hydroxyglutarate oxidase; Provisional; Region: PRK11728
502801000740	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
502801000741	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
502801000742	glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Region: glycerol3P_GlpB; TIGR03378
502801000743	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
502801000744	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
502801000745	Cysteine-rich domain; Region: CCG; pfam02754
502801000746	Cysteine-rich domain; Region: CCG; pfam02754
502801000747	hypothetical protein; Provisional; Region: PRK11615
502801000748	hypothetical protein; Provisional; Region: PRK11212
502801000749	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
502801000750	CPxP  motif; other site
502801000751	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
502801000752	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
502801000753	metal-binding site [ion binding]
502801000754	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
502801000755	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
502801000756	Predicted membrane protein [Function unknown]; Region: COG3714
502801000757	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4517
502801000758	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
502801000759	hypothetical protein; Provisional; Region: PRK10910
502801000760	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
502801000761	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801000762	S-adenosylmethionine binding site [chemical binding]; other site
502801000763	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
502801000764	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
502801000765	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
502801000766	P loop; other site
502801000767	GTP binding site [chemical binding]; other site
502801000768	cell division protein FtsE; Provisional; Region: PRK10908
502801000769	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801000770	Walker A/P-loop; other site
502801000771	ATP binding site [chemical binding]; other site
502801000772	Q-loop/lid; other site
502801000773	ABC transporter signature motif; other site
502801000774	Walker B; other site
502801000775	D-loop; other site
502801000776	H-loop/switch region; other site
502801000777	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
502801000778	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
502801000779	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
502801000780	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
502801000781	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
502801000782	DNA binding residues [nucleotide binding]
502801000783	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
502801000784	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
502801000785	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
502801000786	dimerization interface [polypeptide binding]; other site
502801000787	ligand binding site [chemical binding]; other site
502801000788	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801000789	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
502801000790	TM-ABC transporter signature motif; other site
502801000791	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
502801000792	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
502801000793	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
502801000794	TM-ABC transporter signature motif; other site
502801000795	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
502801000796	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
502801000797	Walker A/P-loop; other site
502801000798	ATP binding site [chemical binding]; other site
502801000799	Q-loop/lid; other site
502801000800	ABC transporter signature motif; other site
502801000801	Walker B; other site
502801000802	D-loop; other site
502801000803	H-loop/switch region; other site
502801000804	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
502801000805	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
502801000806	Walker A/P-loop; other site
502801000807	ATP binding site [chemical binding]; other site
502801000808	Q-loop/lid; other site
502801000809	ABC transporter signature motif; other site
502801000810	Walker B; other site
502801000811	D-loop; other site
502801000812	H-loop/switch region; other site
502801000813	putative fimbrial protein TcfA; Provisional; Region: PRK15308
502801000814	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
502801000815	putative fimbrial protein TcfA; Provisional; Region: PRK15308
502801000816	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
502801000817	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
502801000818	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801000819	dimer interface [polypeptide binding]; other site
502801000820	conserved gate region; other site
502801000821	putative PBP binding loops; other site
502801000822	ABC-ATPase subunit interface; other site
502801000823	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
502801000824	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801000825	dimer interface [polypeptide binding]; other site
502801000826	conserved gate region; other site
502801000827	putative PBP binding loops; other site
502801000828	ABC-ATPase subunit interface; other site
502801000829	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
502801000830	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
502801000831	Walker A/P-loop; other site
502801000832	ATP binding site [chemical binding]; other site
502801000833	Q-loop/lid; other site
502801000834	ABC transporter signature motif; other site
502801000835	Walker B; other site
502801000836	D-loop; other site
502801000837	H-loop/switch region; other site
502801000838	TOBE domain; Region: TOBE_2; pfam08402
502801000839	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
502801000840	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
502801000841	putative active site [active]
502801000842	catalytic site [active]
502801000843	putative metal binding site [ion binding]; other site
502801000844	Predicted permeases [General function prediction only]; Region: COG0679
502801000845	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
502801000846	non-specific DNA binding site [nucleotide binding]; other site
502801000847	salt bridge; other site
502801000848	sequence-specific DNA binding site [nucleotide binding]; other site
502801000849	Predicted Zn peptidase [Amino acid transport and metabolism]; Region: COG2856
502801000850	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
502801000851	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
502801000852	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801000853	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
502801000854	putative dimerization interface [polypeptide binding]; other site
502801000855	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
502801000856	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
502801000857	THF binding site; other site
502801000858	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
502801000859	substrate binding site [chemical binding]; other site
502801000860	THF binding site; other site
502801000861	zinc-binding site [ion binding]; other site
502801000862	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
502801000863	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
502801000864	uridine phosphorylase; Provisional; Region: PRK11178
502801000865	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
502801000866	Protein tyrosine/serine phosphatase [Signal transduction mechanisms]; Region: COG2365
502801000867	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
502801000868	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
502801000869	Carbon starvation protein CstA; Region: CstA; pfam02554
502801000870	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
502801000871	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
502801000872	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
502801000873	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
502801000874	RmuC family; Region: RmuC; pfam02646
502801000875	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
502801000876	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801000877	S-adenosylmethionine binding site [chemical binding]; other site
502801000878	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4627
502801000879	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
502801000880	SCP-2 sterol transfer family; Region: SCP2; pfam02036
502801000881	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
502801000882	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
502801000883	mttA/Hcf106 family; Region: MttA_Hcf106; cl00788
502801000884	sec-independent translocase; Provisional; Region: PRK01770
502801000885	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
502801000886	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
502801000887	active site
502801000888	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
502801000889	dimer interface [polypeptide binding]; other site
502801000890	allosteric magnesium binding site [ion binding]; other site
502801000891	active site
502801000892	aspartate-rich active site metal binding site; other site
502801000893	Schiff base residues; other site
502801000894	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
502801000895	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
502801000896	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
502801000897	heterodimer interface [polypeptide binding]; other site
502801000898	homodimer interface [polypeptide binding]; other site
502801000899	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
502801000900	FMN reductase; Validated; Region: fre; PRK08051
502801000901	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
502801000902	FAD binding pocket [chemical binding]; other site
502801000903	FAD binding motif [chemical binding]; other site
502801000904	phosphate binding motif [ion binding]; other site
502801000905	beta-alpha-beta structure motif; other site
502801000906	NAD binding pocket [chemical binding]; other site
502801000907	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
502801000908	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
502801000909	dimer interface [polypeptide binding]; other site
502801000910	active site
502801000911	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
502801000912	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
502801000913	substrate binding site [chemical binding]; other site
502801000914	oxyanion hole (OAH) forming residues; other site
502801000915	trimer interface [polypeptide binding]; other site
502801000916	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
502801000917	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
502801000918	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
502801000919	proline dipeptidase; Provisional; Region: PRK13607
502801000920	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
502801000921	active site
502801000922	hypothetical protein; Provisional; Region: PRK11568
502801000923	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
502801000924	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
502801000925	potassium transporter; Provisional; Region: PRK10750
502801000926	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
502801000927	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
502801000928	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
502801000929	FAD binding domain; Region: FAD_binding_4; pfam01565
502801000930	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
502801000931	Biotin operon repressor [Transcription]; Region: BirA; COG1654
502801000932	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
502801000933	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
502801000934	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
502801000935	pantothenate kinase; Provisional; Region: PRK05439
502801000936	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
502801000937	ATP-binding site [chemical binding]; other site
502801000938	CoA-binding site [chemical binding]; other site
502801000939	Mg2+-binding site [ion binding]; other site
502801000940	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
502801000941	Coenzyme A binding pocket [chemical binding]; other site
502801000942	elongation factor Tu; Reviewed; Region: PRK00049
502801000943	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
502801000944	G1 box; other site
502801000945	GEF interaction site [polypeptide binding]; other site
502801000946	GTP/Mg2+ binding site [chemical binding]; other site
502801000947	Switch I region; other site
502801000948	G2 box; other site
502801000949	G3 box; other site
502801000950	Switch II region; other site
502801000951	G4 box; other site
502801000952	G5 box; other site
502801000953	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
502801000954	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
502801000955	Antibiotic Binding Site [chemical binding]; other site
502801000956	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
502801000957	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
502801000958	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
502801000959	putative homodimer interface [polypeptide binding]; other site
502801000960	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
502801000961	heterodimer interface [polypeptide binding]; other site
502801000962	homodimer interface [polypeptide binding]; other site
502801000963	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
502801000964	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
502801000965	23S rRNA interface [nucleotide binding]; other site
502801000966	L7/L12 interface [polypeptide binding]; other site
502801000967	putative thiostrepton binding site; other site
502801000968	L25 interface [polypeptide binding]; other site
502801000969	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
502801000970	mRNA/rRNA interface [nucleotide binding]; other site
502801000971	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
502801000972	23S rRNA interface [nucleotide binding]; other site
502801000973	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
502801000974	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
502801000975	core dimer interface [polypeptide binding]; other site
502801000976	peripheral dimer interface [polypeptide binding]; other site
502801000977	L10 interface [polypeptide binding]; other site
502801000978	L11 interface [polypeptide binding]; other site
502801000979	putative EF-Tu interaction site [polypeptide binding]; other site
502801000980	putative EF-G interaction site [polypeptide binding]; other site
502801000981	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
502801000982	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
502801000983	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
502801000984	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
502801000985	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
502801000986	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
502801000987	RPB3 interaction site [polypeptide binding]; other site
502801000988	RPB1 interaction site [polypeptide binding]; other site
502801000989	RPB11 interaction site [polypeptide binding]; other site
502801000990	RPB10 interaction site [polypeptide binding]; other site
502801000991	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
502801000992	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
502801000993	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
502801000994	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
502801000995	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
502801000996	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
502801000997	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
502801000998	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
502801000999	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
502801001000	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
502801001001	DNA binding site [nucleotide binding]
502801001002	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
502801001003	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
502801001004	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801001005	FeS/SAM binding site; other site
502801001006	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
502801001007	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
502801001008	ThiS interaction site; other site
502801001009	putative active site [active]
502801001010	tetramer interface [polypeptide binding]; other site
502801001011	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
502801001012	thiS-thiF/thiG interaction site; other site
502801001013	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
502801001014	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
502801001015	ATP binding site [chemical binding]; other site
502801001016	substrate interface [chemical binding]; other site
502801001017	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
502801001018	thiamine phosphate binding site [chemical binding]; other site
502801001019	active site
502801001020	pyrophosphate binding site [ion binding]; other site
502801001021	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
502801001022	ThiC-associated domain; Region: ThiC-associated; pfam13667
502801001023	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
502801001024	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
502801001025	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
502801001026	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
502801001027	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
502801001028	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
502801001029	putative NADH binding site [chemical binding]; other site
502801001030	putative active site [active]
502801001031	nudix motif; other site
502801001032	putative metal binding site [ion binding]; other site
502801001033	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
502801001034	substrate binding site [chemical binding]; other site
502801001035	active site
502801001036	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
502801001037	Active_site [active]
502801001038	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
502801001039	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
502801001040	IHF dimer interface [polypeptide binding]; other site
502801001041	IHF - DNA interface [nucleotide binding]; other site
502801001042	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
502801001043	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
502801001044	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
502801001045	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
502801001046	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
502801001047	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
502801001048	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
502801001049	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
502801001050	purine monophosphate binding site [chemical binding]; other site
502801001051	dimer interface [polypeptide binding]; other site
502801001052	putative catalytic residues [active]
502801001053	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
502801001054	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
502801001055	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
502801001056	DNA-binding interface [nucleotide binding]; DNA binding site
502801001057	insertion element IS2 transposase InsD; Provisional; Region: PRK14702
502801001058	HTH-like domain; Region: HTH_21; pfam13276
502801001059	Integrase core domain; Region: rve; pfam00665
502801001060	Integrase core domain; Region: rve_3; pfam13683
502801001061	transposase/IS protein; Provisional; Region: PRK09183
502801001062	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801001063	Walker A motif; other site
502801001064	ATP binding site [chemical binding]; other site
502801001065	Walker B motif; other site
502801001066	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
502801001067	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
502801001068	DNA-binding interface [nucleotide binding]; DNA binding site
502801001069	Integrase core domain; Region: rve; pfam00665
502801001070	Abhydrolase family; Region: Abhydrolase_7; pfam12715
502801001071	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
502801001072	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
502801001073	Na binding site [ion binding]; other site
502801001074	Predicted membrane protein [Function unknown]; Region: COG3162
502801001075	acetyl-CoA synthetase; Provisional; Region: PRK00174
502801001076	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
502801001077	active site
502801001078	CoA binding site [chemical binding]; other site
502801001079	acyl-activating enzyme (AAE) consensus motif; other site
502801001080	AMP binding site [chemical binding]; other site
502801001081	acetate binding site [chemical binding]; other site
502801001082	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
502801001083	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
502801001084	two component system sensor kinase SsrB; Provisional; Region: PRK15369
502801001085	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801001086	active site
502801001087	phosphorylation site [posttranslational modification]
502801001088	intermolecular recognition site; other site
502801001089	dimerization interface [polypeptide binding]; other site
502801001090	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801001091	DNA binding residues [nucleotide binding]
502801001092	dimerization interface [polypeptide binding]; other site
502801001093	two component system sensor kinase SsrA; Provisional; Region: PRK15347
502801001094	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801001095	dimer interface [polypeptide binding]; other site
502801001096	phosphorylation site [posttranslational modification]
502801001097	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801001098	ATP binding site [chemical binding]; other site
502801001099	Mg2+ binding site [ion binding]; other site
502801001100	G-X-G motif; other site
502801001101	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801001102	active site
502801001103	phosphorylation site [posttranslational modification]
502801001104	intermolecular recognition site; other site
502801001105	dimerization interface [polypeptide binding]; other site
502801001106	Hpt domain; Region: Hpt; pfam01627
502801001107	outer membrane secretin SsaC; Provisional; Region: PRK15346
502801001108	Prophage endopeptidase tail; Region: Prophage_tail; cl12123
502801001109	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
502801001110	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
502801001111	type III secretion system protein SsaD; Provisional; Region: PRK15367
502801001112	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
502801001113	type III secretion system protein, YseE family; Region: type_III_yscE; TIGR02501
502801001114	Helix-turn-helix domain; Region: HTH_18; pfam12833
502801001115	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801001116	Type III secretion needle MxiH like; Region: MxiH; cl09641
502801001117	type III secretion system protein, SsaH family; Region: type_III_ssaH; TIGR02498
502801001118	Type III secretion needle MxiH like; Region: MxiH; pfam09392
502801001119	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
502801001120	Type III secretion system subunit; Region: T3SS_LEE_assoc; pfam13327
502801001121	type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499
502801001122	type III secretion system protein SsaK; Provisional; Region: PRK15354
502801001123	secretion system apparatus protein SsaV; Provisional; Region: PRK12720
502801001124	FHIPEP family; Region: FHIPEP; pfam00771
502801001125	type III secretion system ATPase; Validated; Region: PRK06820
502801001126	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
502801001127	Walker A motif/ATP binding site; other site
502801001128	Walker B motif; other site
502801001129	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
502801001130	type III secretion system protein SsaQ; Validated; Region: PRK08035
502801001131	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
502801001132	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
502801001133	Type III secretory pathway, component EscS [Intracellular trafficking and secretion]; Region: EscS; COG4794
502801001134	Type III secretory pathway, component EscT [Intracellular trafficking and secretion]; Region: EscT; COG4791
502801001135	secretion system apparatus protein SsaU; Reviewed; Region: PRK12721
502801001136	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
502801001137	putative inner membrane protein; Provisional; Region: PRK11099
502801001138	Sulphur transport; Region: Sulf_transp; pfam04143
502801001139	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
502801001140	CPxP  motif; other site
502801001141	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801001142	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801001143	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
502801001144	putative effector binding pocket; other site
502801001145	dimerization interface [polypeptide binding]; other site
502801001146	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
502801001147	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
502801001148	cystathionine beta-lyase; Provisional; Region: PRK09028
502801001149	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
502801001150	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801001151	catalytic residue [active]
502801001152	hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13548
502801001153	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
502801001154	Walker A/P-loop; other site
502801001155	ATP binding site [chemical binding]; other site
502801001156	Q-loop/lid; other site
502801001157	ABC transporter signature motif; other site
502801001158	Walker B; other site
502801001159	D-loop; other site
502801001160	H-loop/switch region; other site
502801001161	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
502801001162	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801001163	ABC-ATPase subunit  interface; other site
502801001164	dimer interface [polypeptide binding]; other site
502801001165	putative PBP binding regions; other site
502801001166	Hemin binding protein HutB.  These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149
502801001167	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
502801001168	putative hemin binding site; other site
502801001169	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
502801001170	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
502801001171	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
502801001172	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
502801001173	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801001174	N-terminal plug; other site
502801001175	ligand-binding site [chemical binding]; other site
502801001176	Hemin uptake protein hemP; Region: hemP; pfam10636
502801001177	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
502801001178	NADH(P)-binding; Region: NAD_binding_10; pfam13460
502801001179	NAD(P) binding site [chemical binding]; other site
502801001180	putative active site [active]
502801001181	Putative heme iron utilization protein [Inorganic ion transport and metabolism]; Region: HugX; COG3721
502801001182	coproporphyrinogen III oxidase; Provisional; Region: PRK09058
502801001183	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801001184	FeS/SAM binding site; other site
502801001185	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
502801001186	FAD binding site [chemical binding]; other site
502801001187	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cl17326
502801001188	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
502801001189	Protein of unknown function (DUF2983); Region: DUF2983; pfam11202
502801001190	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
502801001191	active site
502801001192	Protein of unknown function (DUF3706); Region: DUF3706; pfam12500
502801001193	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
502801001194	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
502801001195	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
502801001196	putative metal binding site [ion binding]; other site
502801001197	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
502801001198	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
502801001199	putative metal binding site [ion binding]; other site
502801001200	Uncharacterized protein involved in stress response [General function prediction only]; Region: COG4110
502801001201	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
502801001202	putative metal binding site [ion binding]; other site
502801001203	tellurite resistance protein terB; Region: terB; cd07176
502801001204	putative metal binding site [ion binding]; other site
502801001205	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
502801001206	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
502801001207	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
502801001208	putative metal binding site [ion binding]; other site
502801001209	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
502801001210	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
502801001211	putative metal binding site [ion binding]; other site
502801001212	Protein of unknown function (DUF1120); Region: DUF1120; cl05856
502801001213	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
502801001214	PapC N-terminal domain; Region: PapC_N; pfam13954
502801001215	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
502801001216	PapC C-terminal domain; Region: PapC_C; pfam13953
502801001217	putative fimbrial chaperone protein; Provisional; Region: PRK09918
502801001218	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801001219	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
502801001220	Berberine and berberine like; Region: BBE; pfam08031
502801001221	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
502801001222	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
502801001223	Interdomain contacts; other site
502801001224	Cytokine receptor motif; other site
502801001225	chitin-binding domain of Chi A1-like proteins; Region: ChiA1_BD; cd12214
502801001226	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
502801001227	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
502801001228	Autotransporter beta-domain; Region: Autotransporter; smart00869
502801001229	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
502801001230	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
502801001231	UbiA prenyltransferase family; Region: UbiA; pfam01040
502801001232	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
502801001233	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
502801001234	putative acyl-acceptor binding pocket; other site
502801001235	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
502801001236	LexA repressor; Validated; Region: PRK00215
502801001237	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
502801001238	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
502801001239	Catalytic site [active]
502801001240	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
502801001241	metal binding site 2 [ion binding]; metal-binding site
502801001242	putative DNA binding helix; other site
502801001243	metal binding site 1 [ion binding]; metal-binding site
502801001244	dimer interface [polypeptide binding]; other site
502801001245	structural Zn2+ binding site [ion binding]; other site
502801001246	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
502801001247	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
502801001248	FMN binding site [chemical binding]; other site
502801001249	active site
502801001250	catalytic residues [active]
502801001251	substrate binding site [chemical binding]; other site
502801001252	phage shock protein G; Reviewed; Region: pspG; PRK09459
502801001253	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
502801001254	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
502801001255	NADP binding site [chemical binding]; other site
502801001256	dimer interface [polypeptide binding]; other site
502801001257	replicative DNA helicase; Provisional; Region: PRK08006
502801001258	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
502801001259	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
502801001260	Walker A motif; other site
502801001261	ATP binding site [chemical binding]; other site
502801001262	Walker B motif; other site
502801001263	DNA binding loops [nucleotide binding]
502801001264	alanine racemase; Reviewed; Region: alr; PRK00053
502801001265	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
502801001266	active site
502801001267	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
502801001268	substrate binding site [chemical binding]; other site
502801001269	catalytic residues [active]
502801001270	dimer interface [polypeptide binding]; other site
502801001271	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
502801001272	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801001273	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801001274	homodimer interface [polypeptide binding]; other site
502801001275	catalytic residue [active]
502801001276	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
502801001277	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
502801001278	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
502801001279	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
502801001280	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
502801001281	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
502801001282	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
502801001283	dimer interface [polypeptide binding]; other site
502801001284	ssDNA binding site [nucleotide binding]; other site
502801001285	tetramer (dimer of dimers) interface [polypeptide binding]; other site
502801001286	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
502801001287	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
502801001288	lactaldehyde reductase; Region: lactal_redase; TIGR02638
502801001289	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
502801001290	dimer interface [polypeptide binding]; other site
502801001291	active site
502801001292	metal binding site [ion binding]; metal-binding site
502801001293	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
502801001294	intersubunit interface [polypeptide binding]; other site
502801001295	active site
502801001296	Zn2+ binding site [ion binding]; other site
502801001297	L-rhamnose isomerase; Provisional; Region: PRK01076
502801001298	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
502801001299	rhamnulokinase; Provisional; Region: rhaB; PRK10640
502801001300	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
502801001301	N- and C-terminal domain interface [polypeptide binding]; other site
502801001302	active site
502801001303	carbohydrate binding site [chemical binding]; other site
502801001304	ATP binding site [chemical binding]; other site
502801001305	transcriptional activator RhaS; Provisional; Region: PRK13503
502801001306	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
502801001307	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801001308	transcriptional activator RhaR; Provisional; Region: PRK13501
502801001309	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
502801001310	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801001311	L-rhamnose-proton symport protein (RhaT); Region: RhaT; pfam06379
502801001312	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
502801001313	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
502801001314	subtilase cytotoxin subunit B-like protein; Provisional; Region: PRK15265; cl14664
502801001315	Viral enhancin protein; Region: Enhancin; pfam03272
502801001316	Peptidase M60-like family; Region: M60-like; pfam13402
502801001317	putative transcriptional regulator; Provisional; Region: PRK11640
502801001318	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
502801001319	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
502801001320	4Fe-4S binding domain; Region: Fer4; pfam00037
502801001321	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
502801001322	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
502801001323	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
502801001324	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
502801001325	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
502801001326	[4Fe-4S] binding site [ion binding]; other site
502801001327	molybdopterin cofactor binding site; other site
502801001328	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
502801001329	molybdopterin cofactor binding site; other site
502801001330	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
502801001331	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
502801001332	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
502801001333	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
502801001334	DsbD alpha interface [polypeptide binding]; other site
502801001335	catalytic residues [active]
502801001336	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
502801001337	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
502801001338	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
502801001339	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
502801001340	Aspartase; Region: Aspartase; cd01357
502801001341	active sites [active]
502801001342	tetramer interface [polypeptide binding]; other site
502801001343	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
502801001344	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
502801001345	oligomerisation interface [polypeptide binding]; other site
502801001346	mobile loop; other site
502801001347	roof hairpin; other site
502801001348	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
502801001349	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
502801001350	ring oligomerisation interface [polypeptide binding]; other site
502801001351	ATP/Mg binding site [chemical binding]; other site
502801001352	stacking interactions; other site
502801001353	hinge regions; other site
502801001354	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
502801001355	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801001356	Radical SAM superfamily; Region: Radical_SAM; pfam04055
502801001357	FeS/SAM binding site; other site
502801001358	elongation factor P; Validated; Region: PRK00529
502801001359	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
502801001360	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
502801001361	RNA binding site [nucleotide binding]; other site
502801001362	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
502801001363	RNA binding site [nucleotide binding]; other site
502801001364	multidrug efflux system protein; Provisional; Region: PRK11431
502801001365	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
502801001366	Iron-sulfur protein interface; other site
502801001367	proximal quinone binding site [chemical binding]; other site
502801001368	C-subunit interface; other site
502801001369	distal quinone binding site; other site
502801001370	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
502801001371	D-subunit interface [polypeptide binding]; other site
502801001372	Iron-sulfur protein interface; other site
502801001373	proximal quinone binding site [chemical binding]; other site
502801001374	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
502801001375	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
502801001376	catalytic loop [active]
502801001377	iron binding site [ion binding]; other site
502801001378	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
502801001379	L-aspartate oxidase; Provisional; Region: PRK06175
502801001380	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
502801001381	poxB regulator PoxA; Provisional; Region: PRK09350
502801001382	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
502801001383	motif 1; other site
502801001384	dimer interface [polypeptide binding]; other site
502801001385	active site
502801001386	motif 2; other site
502801001387	motif 3; other site
502801001388	putative mechanosensitive channel protein; Provisional; Region: PRK10929
502801001389	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
502801001390	Mechanosensitive ion channel; Region: MS_channel; pfam00924
502801001391	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
502801001392	GTPase RsgA; Reviewed; Region: PRK12288
502801001393	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
502801001394	RNA binding site [nucleotide binding]; other site
502801001395	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
502801001396	GTPase/Zn-binding domain interface [polypeptide binding]; other site
502801001397	GTP/Mg2+ binding site [chemical binding]; other site
502801001398	G4 box; other site
502801001399	G5 box; other site
502801001400	G1 box; other site
502801001401	Switch I region; other site
502801001402	G2 box; other site
502801001403	G3 box; other site
502801001404	Switch II region; other site
502801001405	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
502801001406	catalytic site [active]
502801001407	putative active site [active]
502801001408	putative substrate binding site [chemical binding]; other site
502801001409	dimer interface [polypeptide binding]; other site
502801001410	epoxyqueuosine reductase; Region: TIGR00276
502801001411	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
502801001412	putative carbohydrate kinase; Provisional; Region: PRK10565
502801001413	Uncharacterized conserved protein [Function unknown]; Region: COG0062
502801001414	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
502801001415	putative substrate binding site [chemical binding]; other site
502801001416	putative ATP binding site [chemical binding]; other site
502801001417	ADP-binding protein; Provisional; Region: PRK10646
502801001418	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
502801001419	AMIN domain; Region: AMIN; pfam11741
502801001420	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
502801001421	active site
502801001422	metal binding site [ion binding]; metal-binding site
502801001423	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
502801001424	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
502801001425	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
502801001426	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
502801001427	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
502801001428	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801001429	ATP binding site [chemical binding]; other site
502801001430	Mg2+ binding site [ion binding]; other site
502801001431	G-X-G motif; other site
502801001432	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
502801001433	ATP binding site [chemical binding]; other site
502801001434	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
502801001435	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
502801001436	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
502801001437	bacterial Hfq-like; Region: Hfq; cd01716
502801001438	hexamer interface [polypeptide binding]; other site
502801001439	Sm1 motif; other site
502801001440	RNA binding site [nucleotide binding]; other site
502801001441	Sm2 motif; other site
502801001442	GTPase HflX; Provisional; Region: PRK11058
502801001443	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
502801001444	HflX GTPase family; Region: HflX; cd01878
502801001445	G1 box; other site
502801001446	GTP/Mg2+ binding site [chemical binding]; other site
502801001447	Switch I region; other site
502801001448	G2 box; other site
502801001449	G3 box; other site
502801001450	Switch II region; other site
502801001451	G4 box; other site
502801001452	G5 box; other site
502801001453	FtsH protease regulator HflK; Provisional; Region: PRK10930
502801001454	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
502801001455	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
502801001456	FtsH protease regulator HflC; Provisional; Region: PRK11029
502801001457	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
502801001458	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
502801001459	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
502801001460	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
502801001461	GDP-binding site [chemical binding]; other site
502801001462	ACT binding site; other site
502801001463	IMP binding site; other site
502801001464	transcriptional repressor NsrR; Provisional; Region: PRK11014
502801001465	Rrf2 family protein; Region: rrf2_super; TIGR00738
502801001466	exoribonuclease R; Provisional; Region: PRK11642
502801001467	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
502801001468	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
502801001469	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
502801001470	RNB domain; Region: RNB; pfam00773
502801001471	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
502801001472	RNA binding site [nucleotide binding]; other site
502801001473	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
502801001474	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
502801001475	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
502801001476	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801001477	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
502801001478	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
502801001479	active site
502801001480	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
502801001481	esterase; Provisional; Region: PRK10566
502801001482	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
502801001483	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
502801001484	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
502801001485	generic binding surface I; other site
502801001486	generic binding surface II; other site
502801001487	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
502801001488	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
502801001489	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
502801001490	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
502801001491	Protein of unknown function (DUF3757); Region: DUF3757; pfam12582
502801001492	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
502801001493	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
502801001494	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
502801001495	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
502801001496	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
502801001497	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
502801001498	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
502801001499	Hemerythrin-like domain; Region: Hr-like; cd12108
502801001500	Fe binding site [ion binding]; other site
502801001501	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
502801001502	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
502801001503	active site
502801001504	metal binding site [ion binding]; metal-binding site
502801001505	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
502801001506	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
502801001507	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
502801001508	active site
502801001509	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
502801001510	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
502801001511	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
502801001512	Domain of unknown function DUF21; Region: DUF21; pfam01595
502801001513	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
502801001514	Transporter associated domain; Region: CorC_HlyC; smart01091
502801001515	methionine sulfoxide reductase A; Provisional; Region: PRK00058
502801001516	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
502801001517	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
502801001518	Surface antigen; Region: Bac_surface_Ag; pfam01103
502801001519	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
502801001520	Family of unknown function (DUF490); Region: DUF490; pfam04357
502801001521	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
502801001522	putative active site pocket [active]
502801001523	dimerization interface [polypeptide binding]; other site
502801001524	putative catalytic residue [active]
502801001525	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
502801001526	dimer interface [polypeptide binding]; other site
502801001527	substrate binding site [chemical binding]; other site
502801001528	metal binding sites [ion binding]; metal-binding site
502801001529	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
502801001530	AMP binding site [chemical binding]; other site
502801001531	metal binding site [ion binding]; metal-binding site
502801001532	active site
502801001533	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
502801001534	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
502801001535	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
502801001536	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
502801001537	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
502801001538	arginine repressor; Provisional; Region: PRK05066
502801001539	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
502801001540	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
502801001541	malate dehydrogenase; Provisional; Region: PRK05086
502801001542	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
502801001543	NAD binding site [chemical binding]; other site
502801001544	dimerization interface [polypeptide binding]; other site
502801001545	Substrate binding site [chemical binding]; other site
502801001546	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
502801001547	Mu DNA-binding domain; Region: HTH_Tnp_Mu_1; pfam02316
502801001548	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
502801001549	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
502801001550	substrate binding pocket [chemical binding]; other site
502801001551	chain length determination region; other site
502801001552	substrate-Mg2+ binding site; other site
502801001553	catalytic residues [active]
502801001554	aspartate-rich region 1; other site
502801001555	active site lid residues [active]
502801001556	aspartate-rich region 2; other site
502801001557	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
502801001558	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
502801001559	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
502801001560	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
502801001561	EamA-like transporter family; Region: EamA; pfam00892
502801001562	GTPase CgtA; Reviewed; Region: obgE; PRK12298
502801001563	GTP1/OBG; Region: GTP1_OBG; pfam01018
502801001564	Obg GTPase; Region: Obg; cd01898
502801001565	G1 box; other site
502801001566	GTP/Mg2+ binding site [chemical binding]; other site
502801001567	Switch I region; other site
502801001568	G2 box; other site
502801001569	G3 box; other site
502801001570	Switch II region; other site
502801001571	G4 box; other site
502801001572	G5 box; other site
502801001573	sensor protein BasS/PmrB; Provisional; Region: PRK10755
502801001574	HAMP domain; Region: HAMP; pfam00672
502801001575	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801001576	dimer interface [polypeptide binding]; other site
502801001577	phosphorylation site [posttranslational modification]
502801001578	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801001579	ATP binding site [chemical binding]; other site
502801001580	Mg2+ binding site [ion binding]; other site
502801001581	G-X-G motif; other site
502801001582	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
502801001583	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801001584	active site
502801001585	phosphorylation site [posttranslational modification]
502801001586	intermolecular recognition site; other site
502801001587	dimerization interface [polypeptide binding]; other site
502801001588	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801001589	DNA binding site [nucleotide binding]
502801001590	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
502801001591	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
502801001592	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
502801001593	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
502801001594	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
502801001595	RNA-binding protein YhbY; Provisional; Region: PRK10343
502801001596	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
502801001597	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801001598	S-adenosylmethionine binding site [chemical binding]; other site
502801001599	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
502801001600	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801001601	Walker A motif; other site
502801001602	ATP binding site [chemical binding]; other site
502801001603	Walker B motif; other site
502801001604	arginine finger; other site
502801001605	Peptidase family M41; Region: Peptidase_M41; pfam01434
502801001606	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
502801001607	dihydropteroate synthase; Region: DHPS; TIGR01496
502801001608	substrate binding pocket [chemical binding]; other site
502801001609	dimer interface [polypeptide binding]; other site
502801001610	inhibitor binding site; inhibition site
502801001611	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
502801001612	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
502801001613	active site
502801001614	substrate binding site [chemical binding]; other site
502801001615	metal binding site [ion binding]; metal-binding site
502801001616	Preprotein translocase SecG subunit; Region: SecG; pfam03840
502801001617	ribosome maturation protein RimP; Reviewed; Region: PRK00092
502801001618	Sm and related proteins; Region: Sm_like; cl00259
502801001619	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
502801001620	putative oligomer interface [polypeptide binding]; other site
502801001621	putative RNA binding site [nucleotide binding]; other site
502801001622	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
502801001623	NusA N-terminal domain; Region: NusA_N; pfam08529
502801001624	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
502801001625	RNA binding site [nucleotide binding]; other site
502801001626	homodimer interface [polypeptide binding]; other site
502801001627	NusA-like KH domain; Region: KH_5; pfam13184
502801001628	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
502801001629	G-X-X-G motif; other site
502801001630	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
502801001631	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
502801001632	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
502801001633	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
502801001634	translation initiation factor IF-2; Validated; Region: infB; PRK05306
502801001635	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
502801001636	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
502801001637	G1 box; other site
502801001638	putative GEF interaction site [polypeptide binding]; other site
502801001639	GTP/Mg2+ binding site [chemical binding]; other site
502801001640	Switch I region; other site
502801001641	G2 box; other site
502801001642	G3 box; other site
502801001643	Switch II region; other site
502801001644	G4 box; other site
502801001645	G5 box; other site
502801001646	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
502801001647	Translation-initiation factor 2; Region: IF-2; pfam11987
502801001648	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
502801001649	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
502801001650	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
502801001651	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
502801001652	RNA binding site [nucleotide binding]; other site
502801001653	active site
502801001654	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
502801001655	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
502801001656	16S/18S rRNA binding site [nucleotide binding]; other site
502801001657	S13e-L30e interaction site [polypeptide binding]; other site
502801001658	25S rRNA binding site [nucleotide binding]; other site
502801001659	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
502801001660	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
502801001661	RNase E interface [polypeptide binding]; other site
502801001662	trimer interface [polypeptide binding]; other site
502801001663	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
502801001664	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
502801001665	RNase E interface [polypeptide binding]; other site
502801001666	trimer interface [polypeptide binding]; other site
502801001667	active site
502801001668	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
502801001669	putative nucleic acid binding region [nucleotide binding]; other site
502801001670	G-X-X-G motif; other site
502801001671	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
502801001672	RNA binding site [nucleotide binding]; other site
502801001673	domain interface; other site
502801001674	lipoprotein NlpI; Provisional; Region: PRK11189
502801001675	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
502801001676	binding surface
502801001677	TPR motif; other site
502801001678	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
502801001679	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
502801001680	ATP binding site [chemical binding]; other site
502801001681	Mg++ binding site [ion binding]; other site
502801001682	motif III; other site
502801001683	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801001684	nucleotide binding region [chemical binding]; other site
502801001685	ATP-binding site [chemical binding]; other site
502801001686	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
502801001687	putative RNA binding site [nucleotide binding]; other site
502801001688	Cold shock protein DEAD box A; Region: DEADboxA; pfam12343
502801001689	Phage-related protein [Function unknown]; Region: COG4679
502801001690	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
502801001691	non-specific DNA binding site [nucleotide binding]; other site
502801001692	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
502801001693	salt bridge; other site
502801001694	sequence-specific DNA binding site [nucleotide binding]; other site
502801001695	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801001696	hypothetical protein; Provisional; Region: PRK10508
502801001697	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
502801001698	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
502801001699	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347
502801001700	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
502801001701	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801001702	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801001703	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
502801001704	Protein export membrane protein; Region: SecD_SecF; cl14618
502801001705	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
502801001706	putative protease; Provisional; Region: PRK15447
502801001707	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
502801001708	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
502801001709	Peptidase family U32; Region: Peptidase_U32; pfam01136
502801001710	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
502801001711	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
502801001712	Coenzyme A binding pocket [chemical binding]; other site
502801001713	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
502801001714	GIY-YIG motif/motif A; other site
502801001715	putative active site [active]
502801001716	putative metal binding site [ion binding]; other site
502801001717	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
502801001718	Alginate lyase; Region: Alginate_lyase; pfam05426
502801001719	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
502801001720	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
502801001721	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
502801001722	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
502801001723	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801001724	dimer interface [polypeptide binding]; other site
502801001725	putative PBP binding loops; other site
502801001726	ABC-ATPase subunit interface; other site
502801001727	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
502801001728	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801001729	dimer interface [polypeptide binding]; other site
502801001730	conserved gate region; other site
502801001731	putative PBP binding loops; other site
502801001732	ABC-ATPase subunit interface; other site
502801001733	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
502801001734	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
502801001735	Walker A/P-loop; other site
502801001736	ATP binding site [chemical binding]; other site
502801001737	Q-loop/lid; other site
502801001738	ABC transporter signature motif; other site
502801001739	Walker B; other site
502801001740	D-loop; other site
502801001741	H-loop/switch region; other site
502801001742	TOBE domain; Region: TOBE_2; pfam08402
502801001743	Alginate lyase; Region: Alginate_lyase; pfam05426
502801001744	hypothetical protein; Provisional; Region: PRK03467
502801001745	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
502801001746	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
502801001747	NAD binding site [chemical binding]; other site
502801001748	active site
502801001749	putative hydrolase; Provisional; Region: PRK02113
502801001750	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
502801001751	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
502801001752	Guanylate kinase; Region: Guanylate_kin; pfam00625
502801001753	active site
502801001754	Metal-dependent hydrolase involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: COG3454
502801001755	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
502801001756	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
502801001757	active site
502801001758	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
502801001759	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801001760	Walker A/P-loop; other site
502801001761	ATP binding site [chemical binding]; other site
502801001762	Q-loop/lid; other site
502801001763	ABC transporter signature motif; other site
502801001764	Walker B; other site
502801001765	D-loop; other site
502801001766	H-loop/switch region; other site
502801001767	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
502801001768	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801001769	Walker A/P-loop; other site
502801001770	ATP binding site [chemical binding]; other site
502801001771	Q-loop/lid; other site
502801001772	ABC transporter signature motif; other site
502801001773	Walker B; other site
502801001774	D-loop; other site
502801001775	H-loop/switch region; other site
502801001776	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
502801001777	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
502801001778	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
502801001779	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
502801001780	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnG; COG3624
502801001781	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
502801001782	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801001783	DNA-binding site [nucleotide binding]; DNA binding site
502801001784	UTRA domain; Region: UTRA; pfam07702
502801001785	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
502801001786	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
502801001787	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
502801001788	ATP cone domain; Region: ATP-cone; pfam03477
502801001789	Class III ribonucleotide reductase; Region: RNR_III; cd01675
502801001790	effector binding site; other site
502801001791	active site
502801001792	Zn binding site [ion binding]; other site
502801001793	glycine loop; other site
502801001794	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
502801001795	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801001796	Walker A/P-loop; other site
502801001797	ATP binding site [chemical binding]; other site
502801001798	Q-loop/lid; other site
502801001799	ABC transporter signature motif; other site
502801001800	Walker B; other site
502801001801	D-loop; other site
502801001802	H-loop/switch region; other site
502801001803	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801001804	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
502801001805	Walker A/P-loop; other site
502801001806	ATP binding site [chemical binding]; other site
502801001807	Q-loop/lid; other site
502801001808	ABC transporter signature motif; other site
502801001809	Walker B; other site
502801001810	D-loop; other site
502801001811	H-loop/switch region; other site
502801001812	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
502801001813	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
502801001814	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801001815	dimer interface [polypeptide binding]; other site
502801001816	conserved gate region; other site
502801001817	ABC-ATPase subunit interface; other site
502801001818	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
502801001819	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801001820	dimer interface [polypeptide binding]; other site
502801001821	conserved gate region; other site
502801001822	putative PBP binding loops; other site
502801001823	ABC-ATPase subunit interface; other site
502801001824	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
502801001825	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
502801001826	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
502801001827	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
502801001828	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
502801001829	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
502801001830	RNase E inhibitor protein; Provisional; Region: PRK11191
502801001831	Protein of unknown function (DUF1260); Region: DUF1260; pfam06877
502801001832	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
502801001833	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
502801001834	HIGH motif; other site
502801001835	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
502801001836	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
502801001837	active site
502801001838	KMSKS motif; other site
502801001839	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
502801001840	tRNA binding surface [nucleotide binding]; other site
502801001841	anticodon binding site; other site
502801001842	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
502801001843	DNA polymerase III subunit chi; Validated; Region: PRK05728
502801001844	multifunctional aminopeptidase A; Provisional; Region: PRK00913
502801001845	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
502801001846	interface (dimer of trimers) [polypeptide binding]; other site
502801001847	Substrate-binding/catalytic site; other site
502801001848	Zn-binding sites [ion binding]; other site
502801001849	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
502801001850	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
502801001851	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
502801001852	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
502801001853	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
502801001854	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
502801001855	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
502801001856	ATP binding site [chemical binding]; other site
502801001857	putative Mg++ binding site [ion binding]; other site
502801001858	Glycoside hydrolase family 15, N-terminal domain; Region: GH15_N; cl07672
502801001859	Type I restriction and modification enzyme - subunit R C terminal; Region: EcoR124_C; pfam12008
502801001860	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
502801001861	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
502801001862	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
502801001863	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
502801001864	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
502801001865	active site
502801001866	phosphorylation site [posttranslational modification]
502801001867	hypothetical protein; Provisional; Region: PRK11667
502801001868	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
502801001869	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
502801001870	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
502801001871	putative active site; other site
502801001872	catalytic residue [active]
502801001873	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
502801001874	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
502801001875	ligand binding site [chemical binding]; other site
502801001876	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801001877	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801001878	TM-ABC transporter signature motif; other site
502801001879	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801001880	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801001881	TM-ABC transporter signature motif; other site
502801001882	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
502801001883	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801001884	Walker A/P-loop; other site
502801001885	ATP binding site [chemical binding]; other site
502801001886	Q-loop/lid; other site
502801001887	ABC transporter signature motif; other site
502801001888	Walker B; other site
502801001889	D-loop; other site
502801001890	H-loop/switch region; other site
502801001891	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801001892	transcriptional regulator LsrR; Provisional; Region: PRK15418
502801001893	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
502801001894	non-specific DNA interactions [nucleotide binding]; other site
502801001895	DNA binding site [nucleotide binding]
502801001896	sequence specific DNA binding site [nucleotide binding]; other site
502801001897	putative cAMP binding site [chemical binding]; other site
502801001898	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
502801001899	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
502801001900	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
502801001901	putative N- and C-terminal domain interface [polypeptide binding]; other site
502801001902	putative active site [active]
502801001903	putative MgATP binding site [chemical binding]; other site
502801001904	catalytic site [active]
502801001905	metal binding site [ion binding]; metal-binding site
502801001906	putative carbohydrate binding site [chemical binding]; other site
502801001907	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
502801001908	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
502801001909	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
502801001910	putative active site [active]
502801001911	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
502801001912	O-Antigen ligase; Region: Wzy_C; pfam04932
502801001913	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
502801001914	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
502801001915	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801001916	catalytic residue [active]
502801001917	Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771
502801001918	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
502801001919	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
502801001920	Ubiquitin-like proteins; Region: UBQ; cl00155
502801001921	charged pocket; other site
502801001922	hydrophobic patch; other site
502801001923	molybdopterin biosynthesis-like protein MoeZ; Validated; Region: PRK07878
502801001924	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
502801001925	ATP binding site [chemical binding]; other site
502801001926	substrate interface [chemical binding]; other site
502801001927	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
502801001928	active site residue [active]
502801001929	Protein of unknown function (DUF1049); Region: DUF1049; cl01539
502801001930	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
502801001931	Peptidase family M23; Region: Peptidase_M23; pfam01551
502801001932	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801001933	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
502801001934	Pectinesterase; Region: Pectinesterase; pfam01095
502801001935	putative pectinesterase; Region: PLN02432; cl01911
502801001936	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
502801001937	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
502801001938	metal binding site [ion binding]; metal-binding site
502801001939	active site
502801001940	I-site; other site
502801001941	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
502801001942	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
502801001943	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
502801001944	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801001945	S-adenosylmethionine binding site [chemical binding]; other site
502801001946	DNA polymerase III subunit psi; Validated; Region: PRK06856
502801001947	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
502801001948	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
502801001949	Coenzyme A binding pocket [chemical binding]; other site
502801001950	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
502801001951	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
502801001952	G1 box; other site
502801001953	putative GEF interaction site [polypeptide binding]; other site
502801001954	GTP/Mg2+ binding site [chemical binding]; other site
502801001955	Switch I region; other site
502801001956	G2 box; other site
502801001957	G3 box; other site
502801001958	Switch II region; other site
502801001959	G4 box; other site
502801001960	G5 box; other site
502801001961	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
502801001962	periplasmic protein; Provisional; Region: PRK10568
502801001963	BON domain; Region: BON; pfam04972
502801001964	BON domain; Region: BON; pfam04972
502801001965	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
502801001966	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
502801001967	active site
502801001968	nucleophile elbow; other site
502801001969	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
502801001970	active site
502801001971	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
502801001972	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
502801001973	Nucleoside recognition; Region: Gate; pfam07670
502801001974	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
502801001975	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
502801001976	intersubunit interface [polypeptide binding]; other site
502801001977	active site
502801001978	catalytic residue [active]
502801001979	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
502801001980	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
502801001981	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
502801001982	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
502801001983	phosphopentomutase; Provisional; Region: PRK05362
502801001984	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
502801001985	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
502801001986	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
502801001987	hypothetical protein; Provisional; Region: PRK11246
502801001988	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
502801001989	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801001990	motif II; other site
502801001991	DNA repair protein RadA; Provisional; Region: PRK11823
502801001992	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
502801001993	Walker A motif/ATP binding site; other site
502801001994	ATP binding site [chemical binding]; other site
502801001995	Walker B motif; other site
502801001996	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
502801001997	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
502801001998	non-specific DNA binding site [nucleotide binding]; other site
502801001999	salt bridge; other site
502801002000	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
502801002001	sequence-specific DNA binding site [nucleotide binding]; other site
502801002002	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
502801002003	active site
502801002004	nucleotide binding site [chemical binding]; other site
502801002005	HIGH motif; other site
502801002006	KMSKS motif; other site
502801002007	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
502801002008	Fic family protein [Function unknown]; Region: COG3177
502801002009	Domain of unknown function (DUF4172); Region: DUF4172; pfam13776
502801002010	Fic/DOC family; Region: Fic; pfam02661
502801002011	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
502801002012	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801002013	Walker A/P-loop; other site
502801002014	ATP binding site [chemical binding]; other site
502801002015	Q-loop/lid; other site
502801002016	ABC transporter signature motif; other site
502801002017	Walker B; other site
502801002018	D-loop; other site
502801002019	H-loop/switch region; other site
502801002020	ABC transporter; Region: ABC_tran_2; pfam12848
502801002021	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
502801002022	putative outer membrane lipoprotein; Provisional; Region: PRK09967
502801002023	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
502801002024	ligand binding site [chemical binding]; other site
502801002025	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
502801002026	HAMP domain; Region: HAMP; pfam00672
502801002027	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
502801002028	metal binding site [ion binding]; metal-binding site
502801002029	active site
502801002030	I-site; other site
502801002031	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
502801002032	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
502801002033	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
502801002034	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
502801002035	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
502801002036	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801002037	motif II; other site
502801002038	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
502801002039	lytic murein transglycosylase; Provisional; Region: PRK11619
502801002040	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
502801002041	N-acetyl-D-glucosamine binding site [chemical binding]; other site
502801002042	catalytic residue [active]
502801002043	Trp operon repressor; Provisional; Region: PRK01381
502801002044	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
502801002045	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
502801002046	catalytic core [active]
502801002047	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
502801002048	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801002049	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
502801002050	hypothetical protein; Provisional; Region: PRK10756
502801002051	CreA protein; Region: CreA; pfam05981
502801002052	two-component response regulator; Provisional; Region: PRK11173
502801002053	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801002054	active site
502801002055	phosphorylation site [posttranslational modification]
502801002056	intermolecular recognition site; other site
502801002057	dimerization interface [polypeptide binding]; other site
502801002058	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801002059	DNA binding site [nucleotide binding]
502801002060	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
502801002061	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
502801002062	putative catalytic residues [active]
502801002063	putative nucleotide binding site [chemical binding]; other site
502801002064	putative aspartate binding site [chemical binding]; other site
502801002065	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
502801002066	dimer interface [polypeptide binding]; other site
502801002067	putative threonine allosteric regulatory site; other site
502801002068	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
502801002069	putative threonine allosteric regulatory site; other site
502801002070	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
502801002071	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
502801002072	homoserine kinase; Provisional; Region: PRK01212
502801002073	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
502801002074	threonine synthase; Validated; Region: PRK09225
502801002075	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
502801002076	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801002077	catalytic residue [active]
502801002078	hypothetical protein; Validated; Region: PRK02101
502801002079	transaldolase-like protein; Provisional; Region: PTZ00411
502801002080	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
502801002081	active site
502801002082	dimer interface [polypeptide binding]; other site
502801002083	catalytic residue [active]
502801002084	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
502801002085	MPT binding site; other site
502801002086	trimer interface [polypeptide binding]; other site
502801002087	metabolite-proton symporter; Region: 2A0106; TIGR00883
502801002088	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801002089	putative substrate translocation pore; other site
502801002090	Beta/Gamma crystallin; Region: Crystall; cl02528
502801002091	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
502801002092	hypothetical protein; Provisional; Region: PRK10659
502801002093	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
502801002094	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
502801002095	nucleotide binding site [chemical binding]; other site
502801002096	chaperone protein DnaJ; Provisional; Region: PRK10767
502801002097	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
502801002098	HSP70 interaction site [polypeptide binding]; other site
502801002099	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
502801002100	substrate binding site [polypeptide binding]; other site
502801002101	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
502801002102	Zn binding sites [ion binding]; other site
502801002103	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
502801002104	dimer interface [polypeptide binding]; other site
502801002105	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
502801002106	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
502801002107	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801002108	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
502801002109	putative dimerization interface [polypeptide binding]; other site
502801002110	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
502801002111	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
502801002112	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
502801002113	active site
502801002114	Riboflavin kinase; Region: Flavokinase; smart00904
502801002115	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
502801002116	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
502801002117	active site
502801002118	HIGH motif; other site
502801002119	nucleotide binding site [chemical binding]; other site
502801002120	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
502801002121	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
502801002122	active site
502801002123	KMSKS motif; other site
502801002124	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
502801002125	tRNA binding surface [nucleotide binding]; other site
502801002126	anticodon binding site; other site
502801002127	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
502801002128	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
502801002129	lipoprotein signal peptidase; Provisional; Region: PRK14787
502801002130	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
502801002131	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
502801002132	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
502801002133	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
502801002134	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
502801002135	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
502801002136	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
502801002137	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
502801002138	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
502801002139	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
502801002140	catalytic site [active]
502801002141	subunit interface [polypeptide binding]; other site
502801002142	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
502801002143	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
502801002144	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
502801002145	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
502801002146	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
502801002147	ATP-grasp domain; Region: ATP-grasp_4; cl17255
502801002148	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
502801002149	IMP binding site; other site
502801002150	dimer interface [polypeptide binding]; other site
502801002151	interdomain contacts; other site
502801002152	partial ornithine binding site; other site
502801002153	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
502801002154	Uncharacterized conserved protein [Function unknown]; Region: COG2966
502801002155	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
502801002156	hypothetical protein; Provisional; Region: PRK09917
502801002157	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
502801002158	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
502801002159	folate binding site [chemical binding]; other site
502801002160	NADP+ binding site [chemical binding]; other site
502801002161	Protein of unknown function (DUF3757); Region: DUF3757; pfam12582
502801002162	diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166
502801002163	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
502801002164	active site
502801002165	metal binding site [ion binding]; metal-binding site
502801002166	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
502801002167	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
502801002168	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801002169	S-adenosylmethionine binding site [chemical binding]; other site
502801002170	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
502801002171	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
502801002172	SurA N-terminal domain; Region: SurA_N; pfam09312
502801002173	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
502801002174	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
502801002175	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
502801002176	OstA-like protein; Region: OstA; pfam03968
502801002177	Organic solvent tolerance protein; Region: OstA_C; pfam04453
502801002178	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
502801002179	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
502801002180	putative metal binding site [ion binding]; other site
502801002181	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
502801002182	HSP70 interaction site [polypeptide binding]; other site
502801002183	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
502801002184	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
502801002185	active site
502801002186	Uncharacterized conserved protein [Function unknown]; Region: COG5419
502801002187	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
502801002188	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
502801002189	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
502801002190	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
502801002191	Protein of unknown function (DUF877); Region: DUF877; pfam05943
502801002192	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
502801002193	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
502801002194	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
502801002195	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
502801002196	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
502801002197	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
502801002198	Clp amino terminal domain; Region: Clp_N; pfam02861
502801002199	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801002200	Walker A motif; other site
502801002201	ATP binding site [chemical binding]; other site
502801002202	Walker B motif; other site
502801002203	arginine finger; other site
502801002204	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801002205	Walker A motif; other site
502801002206	ATP binding site [chemical binding]; other site
502801002207	Walker B motif; other site
502801002208	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
502801002209	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
502801002210	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
502801002211	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
502801002212	Uncharacterized protein conserved in bacteria (DUF2169); Region: DUF2169; pfam09937
502801002213	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
502801002214	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
502801002215	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
502801002216	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
502801002217	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
502801002218	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
502801002219	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
502801002220	Protein of unknown function (DUF3540); Region: DUF3540; pfam12059
502801002221	Domain of unknown function (DUF4150); Region: DUF4150; pfam13665
502801002222	Type VI secretion lipoprotein; Region: T6SS-SciN; cl01405
502801002223	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
502801002224	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
502801002225	hypothetical protein; Provisional; Region: PRK07034
502801002226	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
502801002227	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
502801002228	ligand binding site [chemical binding]; other site
502801002229	type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348
502801002230	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
502801002231	G1 box; other site
502801002232	GTP/Mg2+ binding site [chemical binding]; other site
502801002233	G2 box; other site
502801002234	G3 box; other site
502801002235	Switch II region; other site
502801002236	G4 box; other site
502801002237	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
502801002238	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
502801002239	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801002240	ATP-dependent helicase HepA; Validated; Region: PRK04914
502801002241	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
502801002242	ATP binding site [chemical binding]; other site
502801002243	putative Mg++ binding site [ion binding]; other site
502801002244	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801002245	nucleotide binding region [chemical binding]; other site
502801002246	ATP-binding site [chemical binding]; other site
502801002247	DNA polymerase II; Reviewed; Region: PRK05762
502801002248	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
502801002249	active site
502801002250	catalytic site [active]
502801002251	substrate binding site [chemical binding]; other site
502801002252	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
502801002253	active site
502801002254	metal-binding site
502801002255	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
502801002256	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
502801002257	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
502801002258	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
502801002259	Walker A/P-loop; other site
502801002260	ATP binding site [chemical binding]; other site
502801002261	Q-loop/lid; other site
502801002262	ABC transporter signature motif; other site
502801002263	Walker B; other site
502801002264	D-loop; other site
502801002265	H-loop/switch region; other site
502801002266	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
502801002267	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801002268	dimer interface [polypeptide binding]; other site
502801002269	conserved gate region; other site
502801002270	putative PBP binding loops; other site
502801002271	ABC-ATPase subunit interface; other site
502801002272	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801002273	dimer interface [polypeptide binding]; other site
502801002274	conserved gate region; other site
502801002275	putative PBP binding loops; other site
502801002276	ABC-ATPase subunit interface; other site
502801002277	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
502801002278	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
502801002279	Uncharacterized conserved protein [Function unknown]; Region: COG5464
502801002280	HTH-like domain; Region: HTH_21; pfam13276
502801002281	transcriptional regulator SgrR; Provisional; Region: PRK13626
502801002282	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
502801002283	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
502801002284	sugar efflux transporter; Region: 2A0120; TIGR00899
502801002285	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801002286	putative substrate translocation pore; other site
502801002287	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
502801002288	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
502801002289	substrate binding site [chemical binding]; other site
502801002290	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
502801002291	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
502801002292	substrate binding site [chemical binding]; other site
502801002293	ligand binding site [chemical binding]; other site
502801002294	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
502801002295	tartrate dehydrogenase; Region: TTC; TIGR02089
502801002296	2-isopropylmalate synthase; Validated; Region: PRK00915
502801002297	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
502801002298	active site
502801002299	catalytic residues [active]
502801002300	metal binding site [ion binding]; metal-binding site
502801002301	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
502801002302	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
502801002303	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801002304	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
502801002305	putative substrate binding pocket [chemical binding]; other site
502801002306	putative dimerization interface [polypeptide binding]; other site
502801002307	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
502801002308	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
502801002309	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
502801002310	acyl-activating enzyme (AAE) consensus motif; other site
502801002311	acyl-activating enzyme (AAE) consensus motif; other site
502801002312	putative AMP binding site [chemical binding]; other site
502801002313	putative active site [active]
502801002314	putative CoA binding site [chemical binding]; other site
502801002315	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
502801002316	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
502801002317	PYR/PP interface [polypeptide binding]; other site
502801002318	dimer interface [polypeptide binding]; other site
502801002319	TPP binding site [chemical binding]; other site
502801002320	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
502801002321	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
502801002322	TPP-binding site [chemical binding]; other site
502801002323	dimer interface [polypeptide binding]; other site
502801002324	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
502801002325	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
502801002326	putative valine binding site [chemical binding]; other site
502801002327	dimer interface [polypeptide binding]; other site
502801002328	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
502801002329	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
502801002330	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801002331	DNA binding site [nucleotide binding]
502801002332	domain linker motif; other site
502801002333	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
502801002334	dimerization interface [polypeptide binding]; other site
502801002335	ligand binding site [chemical binding]; other site
502801002336	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
502801002337	cell division protein MraZ; Reviewed; Region: PRK00326
502801002338	MraZ protein; Region: MraZ; pfam02381
502801002339	MraZ protein; Region: MraZ; pfam02381
502801002340	MraW methylase family; Region: Methyltransf_5; pfam01795
502801002341	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
502801002342	cell division protein FtsL; Provisional; Region: PRK10772
502801002343	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
502801002344	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
502801002345	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
502801002346	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
502801002347	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
502801002348	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
502801002349	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
502801002350	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
502801002351	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
502801002352	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
502801002353	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
502801002354	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
502801002355	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
502801002356	Mg++ binding site [ion binding]; other site
502801002357	putative catalytic motif [active]
502801002358	putative substrate binding site [chemical binding]; other site
502801002359	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
502801002360	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cl00656
502801002361	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
502801002362	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
502801002363	cell division protein FtsW; Provisional; Region: PRK10774
502801002364	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
502801002365	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
502801002366	active site
502801002367	homodimer interface [polypeptide binding]; other site
502801002368	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
502801002369	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
502801002370	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
502801002371	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
502801002372	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
502801002373	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
502801002374	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
502801002375	cell division protein FtsQ; Provisional; Region: PRK10775
502801002376	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
502801002377	Cell division protein FtsQ; Region: FtsQ; pfam03799
502801002378	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
502801002379	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
502801002380	Cell division protein FtsA; Region: FtsA; pfam14450
502801002381	cell division protein FtsZ; Validated; Region: PRK09330
502801002382	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
502801002383	nucleotide binding site [chemical binding]; other site
502801002384	SulA interaction site; other site
502801002385	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
502801002386	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
502801002387	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4701
502801002388	SecA regulator SecM; Provisional; Region: PRK02943
502801002389	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
502801002390	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
502801002391	SEC-C motif; Region: SEC-C; pfam02810
502801002392	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
502801002393	active site
502801002394	8-oxo-dGMP binding site [chemical binding]; other site
502801002395	nudix motif; other site
502801002396	metal binding site [ion binding]; metal-binding site
502801002397	Transposase IS200 like; Region: Y1_Tnp; pfam01797
502801002398	DNA gyrase inhibitor; Reviewed; Region: PRK00418
502801002399	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
502801002400	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
502801002401	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
502801002402	CoA-binding site [chemical binding]; other site
502801002403	ATP-binding [chemical binding]; other site
502801002404	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
502801002405	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
502801002406	active site
502801002407	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
502801002408	MULE transposase domain; Region: MULE; pfam10551
502801002409	type IV pilin biogenesis protein; Provisional; Region: PRK10573
502801002410	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
502801002411	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
502801002412	hypothetical protein; Provisional; Region: PRK10436
502801002413	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
502801002414	Walker A motif; other site
502801002415	ATP binding site [chemical binding]; other site
502801002416	Walker B motif; other site
502801002417	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
502801002418	putative major pilin subunit; Provisional; Region: PRK10574
502801002419	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
502801002420	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
502801002421	dimerization interface [polypeptide binding]; other site
502801002422	active site
502801002423	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
502801002424	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
502801002425	amidase catalytic site [active]
502801002426	Zn binding residues [ion binding]; other site
502801002427	substrate binding site [chemical binding]; other site
502801002428	regulatory protein AmpE; Provisional; Region: PRK10987
502801002429	aromatic amino acid transporter; Provisional; Region: PRK10238
502801002430	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
502801002431	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801002432	DNA-binding site [nucleotide binding]; DNA binding site
502801002433	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
502801002434	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
502801002435	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
502801002436	dimer interface [polypeptide binding]; other site
502801002437	TPP-binding site [chemical binding]; other site
502801002438	dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855
502801002439	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
502801002440	E3 interaction surface; other site
502801002441	lipoyl attachment site [posttranslational modification]; other site
502801002442	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
502801002443	E3 interaction surface; other site
502801002444	lipoyl attachment site [posttranslational modification]; other site
502801002445	e3 binding domain; Region: E3_binding; pfam02817
502801002446	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
502801002447	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
502801002448	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
502801002449	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
502801002450	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
502801002451	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
502801002452	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
502801002453	substrate binding site [chemical binding]; other site
502801002454	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
502801002455	substrate binding site [chemical binding]; other site
502801002456	ligand binding site [chemical binding]; other site
502801002457	hypothetical protein; Provisional; Region: PRK05248
502801002458	aromatic amino acid exporter; Provisional; Region: PRK11689
502801002459	EamA-like transporter family; Region: EamA; cl17759
502801002460	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
502801002461	spermidine synthase; Provisional; Region: PRK00811
502801002462	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801002463	S-adenosylmethionine binding site [chemical binding]; other site
502801002464	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
502801002465	multicopper oxidase; Provisional; Region: PRK10965
502801002466	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
502801002467	Multicopper oxidase; Region: Cu-oxidase; pfam00394
502801002468	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
502801002469	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
502801002470	active site
502801002471	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
502801002472	active site clefts [active]
502801002473	zinc binding site [ion binding]; other site
502801002474	dimer interface [polypeptide binding]; other site
502801002475	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
502801002476	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
502801002477	Walker A/P-loop; other site
502801002478	ATP binding site [chemical binding]; other site
502801002479	Q-loop/lid; other site
502801002480	ABC transporter signature motif; other site
502801002481	Walker B; other site
502801002482	D-loop; other site
502801002483	H-loop/switch region; other site
502801002484	inner membrane transport permease; Provisional; Region: PRK15066
502801002485	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
502801002486	Bacterial SH3 domain; Region: SH3_3; cl17532
502801002487	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
502801002488	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
502801002489	putative active site [active]
502801002490	putative metal binding site [ion binding]; other site
502801002491	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
502801002492	tetramerization interface [polypeptide binding]; other site
502801002493	active site
502801002494	pantoate--beta-alanine ligase; Region: panC; TIGR00018
502801002495	Pantoate-beta-alanine ligase; Region: PanC; cd00560
502801002496	active site
502801002497	ATP-binding site [chemical binding]; other site
502801002498	pantoate-binding site; other site
502801002499	HXXH motif; other site
502801002500	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
502801002501	oligomerization interface [polypeptide binding]; other site
502801002502	active site
502801002503	metal binding site [ion binding]; metal-binding site
502801002504	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
502801002505	catalytic center binding site [active]
502801002506	ATP binding site [chemical binding]; other site
502801002507	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
502801002508	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
502801002509	active site
502801002510	NTP binding site [chemical binding]; other site
502801002511	metal binding triad [ion binding]; metal-binding site
502801002512	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
502801002513	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
502801002514	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
502801002515	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
502801002516	active site
502801002517	nucleotide binding site [chemical binding]; other site
502801002518	HIGH motif; other site
502801002519	KMSKS motif; other site
502801002520	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
502801002521	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
502801002522	2'-5' RNA ligase; Provisional; Region: PRK15124
502801002523	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
502801002524	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
502801002525	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
502801002526	ATP binding site [chemical binding]; other site
502801002527	putative Mg++ binding site [ion binding]; other site
502801002528	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801002529	nucleotide binding region [chemical binding]; other site
502801002530	ATP-binding site [chemical binding]; other site
502801002531	Helicase associated domain (HA2); Region: HA2; pfam04408
502801002532	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
502801002533	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
502801002534	Transglycosylase; Region: Transgly; pfam00912
502801002535	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
502801002536	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
502801002537	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
502801002538	Walker A/P-loop; other site
502801002539	ATP binding site [chemical binding]; other site
502801002540	Q-loop/lid; other site
502801002541	ABC transporter signature motif; other site
502801002542	Walker B; other site
502801002543	D-loop; other site
502801002544	H-loop/switch region; other site
502801002545	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
502801002546	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
502801002547	siderophore binding site; other site
502801002548	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
502801002549	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801002550	ABC-ATPase subunit  interface; other site
502801002551	dimer interface [polypeptide binding]; other site
502801002552	putative PBP binding regions; other site
502801002553	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801002554	ABC-ATPase subunit  interface; other site
502801002555	dimer interface [polypeptide binding]; other site
502801002556	putative PBP binding regions; other site
502801002557	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
502801002558	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
502801002559	inhibitor-cofactor binding pocket; inhibition site
502801002560	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801002561	catalytic residue [active]
502801002562	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
502801002563	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
502801002564	Cl- selectivity filter; other site
502801002565	Cl- binding residues [ion binding]; other site
502801002566	pore gating glutamate residue; other site
502801002567	dimer interface [polypeptide binding]; other site
502801002568	H+/Cl- coupling transport residue; other site
502801002569	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
502801002570	hypothetical protein; Provisional; Region: PRK10578
502801002571	UPF0126 domain; Region: UPF0126; pfam03458
502801002572	UPF0126 domain; Region: UPF0126; pfam03458
502801002573	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
502801002574	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
502801002575	cobalamin binding residues [chemical binding]; other site
502801002576	putative BtuC binding residues; other site
502801002577	dimer interface [polypeptide binding]; other site
502801002578	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
502801002579	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
502801002580	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
502801002581	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
502801002582	Zn2+ binding site [ion binding]; other site
502801002583	Mg2+ binding site [ion binding]; other site
502801002584	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
502801002585	serine endoprotease; Provisional; Region: PRK10942
502801002586	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
502801002587	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
502801002588	protein binding site [polypeptide binding]; other site
502801002589	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
502801002590	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
502801002591	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
502801002592	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801002593	dimerization interface [polypeptide binding]; other site
502801002594	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801002595	dimer interface [polypeptide binding]; other site
502801002596	phosphorylation site [posttranslational modification]
502801002597	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801002598	ATP binding site [chemical binding]; other site
502801002599	Mg2+ binding site [ion binding]; other site
502801002600	G-X-G motif; other site
502801002601	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
502801002602	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801002603	active site
502801002604	phosphorylation site [posttranslational modification]
502801002605	intermolecular recognition site; other site
502801002606	dimerization interface [polypeptide binding]; other site
502801002607	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
502801002608	putative binding surface; other site
502801002609	active site
502801002610	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
502801002611	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
502801002612	HD domain; Region: HD_4; pfam13328
502801002613	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
502801002614	synthetase active site [active]
502801002615	NTP binding site [chemical binding]; other site
502801002616	metal binding site [ion binding]; metal-binding site
502801002617	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
502801002618	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
502801002619	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
502801002620	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
502801002621	homodimer interface [polypeptide binding]; other site
502801002622	metal binding site [ion binding]; metal-binding site
502801002623	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
502801002624	homodimer interface [polypeptide binding]; other site
502801002625	active site
502801002626	putative chemical substrate binding site [chemical binding]; other site
502801002627	metal binding site [ion binding]; metal-binding site
502801002628	CTP synthetase; Validated; Region: pyrG; PRK05380
502801002629	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
502801002630	Catalytic site [active]
502801002631	active site
502801002632	UTP binding site [chemical binding]; other site
502801002633	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
502801002634	active site
502801002635	putative oxyanion hole; other site
502801002636	catalytic triad [active]
502801002637	enolase; Provisional; Region: eno; PRK00077
502801002638	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
502801002639	dimer interface [polypeptide binding]; other site
502801002640	metal binding site [ion binding]; metal-binding site
502801002641	substrate binding pocket [chemical binding]; other site
502801002642	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
502801002643	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
502801002644	E-class dimer interface [polypeptide binding]; other site
502801002645	P-class dimer interface [polypeptide binding]; other site
502801002646	active site
502801002647	Cu2+ binding site [ion binding]; other site
502801002648	Zn2+ binding site [ion binding]; other site
502801002649	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
502801002650	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
502801002651	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
502801002652	active site
502801002653	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
502801002654	Flavodoxin; Region: Flavodoxin_1; pfam00258
502801002655	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
502801002656	FAD binding pocket [chemical binding]; other site
502801002657	FAD binding motif [chemical binding]; other site
502801002658	catalytic residues [active]
502801002659	NAD binding pocket [chemical binding]; other site
502801002660	phosphate binding motif [ion binding]; other site
502801002661	beta-alpha-beta structure motif; other site
502801002662	sulfite reductase subunit beta; Provisional; Region: PRK13504
502801002663	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
502801002664	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
502801002665	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
502801002666	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
502801002667	Active Sites [active]
502801002668	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
502801002669	YcfA-like protein; Region: YcfA; pfam07927
502801002670	siroheme synthase; Provisional; Region: cysG; PRK10637
502801002671	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
502801002672	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
502801002673	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
502801002674	active site
502801002675	SAM binding site [chemical binding]; other site
502801002676	homodimer interface [polypeptide binding]; other site
502801002677	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
502801002678	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
502801002679	Active Sites [active]
502801002680	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
502801002681	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
502801002682	CysD dimerization site [polypeptide binding]; other site
502801002683	G1 box; other site
502801002684	putative GEF interaction site [polypeptide binding]; other site
502801002685	GTP/Mg2+ binding site [chemical binding]; other site
502801002686	Switch I region; other site
502801002687	G2 box; other site
502801002688	G3 box; other site
502801002689	Switch II region; other site
502801002690	G4 box; other site
502801002691	G5 box; other site
502801002692	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
502801002693	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
502801002694	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
502801002695	ligand-binding site [chemical binding]; other site
502801002696	hypothetical protein; Provisional; Region: PRK10726
502801002697	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
502801002698	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
502801002699	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
502801002700	substrate binding site; other site
502801002701	dimer interface; other site
502801002702	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
502801002703	homotrimer interaction site [polypeptide binding]; other site
502801002704	zinc binding site [ion binding]; other site
502801002705	CDP-binding sites; other site
502801002706	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
502801002707	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
502801002708	Permutation of conserved domain; other site
502801002709	active site
502801002710	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
502801002711	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
502801002712	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801002713	S-adenosylmethionine binding site [chemical binding]; other site
502801002714	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
502801002715	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
502801002716	Peptidase family M23; Region: Peptidase_M23; pfam01551
502801002717	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
502801002718	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
502801002719	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
502801002720	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
502801002721	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
502801002722	DNA binding residues [nucleotide binding]
502801002723	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
502801002724	MutS domain I; Region: MutS_I; pfam01624
502801002725	MutS domain II; Region: MutS_II; pfam05188
502801002726	MutS domain III; Region: MutS_III; pfam05192
502801002727	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
502801002728	Walker A/P-loop; other site
502801002729	ATP binding site [chemical binding]; other site
502801002730	Q-loop/lid; other site
502801002731	ABC transporter signature motif; other site
502801002732	Walker B; other site
502801002733	D-loop; other site
502801002734	H-loop/switch region; other site
502801002735	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
502801002736	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
502801002737	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH2; cd08256
502801002738	putative NAD(P) binding site [chemical binding]; other site
502801002739	catalytic Zn binding site [ion binding]; other site
502801002740	structural Zn binding site [ion binding]; other site
502801002741	short chain dehydrogenase; Provisional; Region: PRK06841
502801002742	classical (c) SDRs; Region: SDR_c; cd05233
502801002743	NAD(P) binding site [chemical binding]; other site
502801002744	active site
502801002745	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
502801002746	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
502801002747	DAK2 domain; Region: Dak2; pfam02734
502801002748	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
502801002749	Helix-turn-helix domain; Region: HTH_28; pfam13518
502801002750	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
502801002751	arsenical pump membrane protein; Provisional; Region: PRK15445
502801002752	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
502801002753	transmembrane helices; other site
502801002754	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
502801002755	dimerization interface [polypeptide binding]; other site
502801002756	putative DNA binding site [nucleotide binding]; other site
502801002757	putative Zn2+ binding site [ion binding]; other site
502801002758	FaeA-like protein; Region: FaeA; pfam04703
502801002759	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
502801002760	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801002761	substrate binding pocket [chemical binding]; other site
502801002762	membrane-bound complex binding site; other site
502801002763	hinge residues; other site
502801002764	Haem-binding domain; Region: Haem_bd; pfam14376
502801002765	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
502801002766	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
502801002767	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801002768	N-terminal plug; other site
502801002769	ligand-binding site [chemical binding]; other site
502801002770	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
502801002771	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
502801002772	active site
502801002773	Protein of unknown function (DUF3423); Region: DUF3423; pfam11903
502801002774	fumarate hydratase; Provisional; Region: PRK15389
502801002775	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
502801002776	Fumarase C-terminus; Region: Fumerase_C; pfam05683
502801002777	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
502801002778	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
502801002779	putative N- and C-terminal domain interface [polypeptide binding]; other site
502801002780	putative active site [active]
502801002781	MgATP binding site [chemical binding]; other site
502801002782	catalytic site [active]
502801002783	metal binding site [ion binding]; metal-binding site
502801002784	putative xylulose binding site [chemical binding]; other site
502801002785	Putative L-xylulose-5-phosphate 3-epimerase [Carbohydrate transport and metabolism]; Region: SgaU; COG3623
502801002786	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
502801002787	AP (apurinic/apyrimidinic) site pocket; other site
502801002788	DNA interaction; other site
502801002789	Metal-binding active site; metal-binding site
502801002790	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801002791	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801002792	TM-ABC transporter signature motif; other site
502801002793	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801002794	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801002795	TM-ABC transporter signature motif; other site
502801002796	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801002797	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801002798	Walker A/P-loop; other site
502801002799	ATP binding site [chemical binding]; other site
502801002800	Q-loop/lid; other site
502801002801	ABC transporter signature motif; other site
502801002802	Walker B; other site
502801002803	D-loop; other site
502801002804	H-loop/switch region; other site
502801002805	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801002806	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
502801002807	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
502801002808	ligand binding site [chemical binding]; other site
502801002809	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
502801002810	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
502801002811	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
502801002812	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK13213
502801002813	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
502801002814	intersubunit interface [polypeptide binding]; other site
502801002815	active site
502801002816	Zn2+ binding site [ion binding]; other site
502801002817	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
502801002818	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
502801002819	putative [Fe4-S4] binding site [ion binding]; other site
502801002820	putative molybdopterin cofactor binding site [chemical binding]; other site
502801002821	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
502801002822	putative molybdopterin cofactor binding site; other site
502801002823	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
502801002824	4Fe-4S binding domain; Region: Fer4; cl02805
502801002825	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
502801002826	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
502801002827	cytochrome b561; Provisional; Region: PRK11513
502801002828	Soluble cytochrome b562 [Energy production and conversion]; Region: CybC; COG3783
502801002829	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
502801002830	N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649
502801002831	dimer interface [polypeptide binding]; other site
502801002832	active site
502801002833	heme binding site [chemical binding]; other site
502801002834	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
502801002835	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
502801002836	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
502801002837	ligand binding site [chemical binding]; other site
502801002838	dimerization interface [polypeptide binding]; other site
502801002839	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5618
502801002840	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801002841	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801002842	Walker A/P-loop; other site
502801002843	ATP binding site [chemical binding]; other site
502801002844	Q-loop/lid; other site
502801002845	ABC transporter signature motif; other site
502801002846	Walker B; other site
502801002847	D-loop; other site
502801002848	H-loop/switch region; other site
502801002849	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801002850	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801002851	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801002852	TM-ABC transporter signature motif; other site
502801002853	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
502801002854	TPP-binding site [chemical binding]; other site
502801002855	dimer interface [polypeptide binding]; other site
502801002856	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
502801002857	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
502801002858	PYR/PP interface [polypeptide binding]; other site
502801002859	dimer interface [polypeptide binding]; other site
502801002860	TPP binding site [chemical binding]; other site
502801002861	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
502801002862	Glycerol kinase [Energy production and conversion]; Region: GlpK; COG0554
502801002863	bacterial glycerol kinase 2-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_GK2_bacteria; cd07791
502801002864	N- and C-terminal domain interface [polypeptide binding]; other site
502801002865	active site
502801002866	MgATP binding site [chemical binding]; other site
502801002867	catalytic site [active]
502801002868	metal binding site [ion binding]; metal-binding site
502801002869	putative homotetramer interface [polypeptide binding]; other site
502801002870	putative homodimer interface [polypeptide binding]; other site
502801002871	glycerol binding site [chemical binding]; other site
502801002872	L-fucose isomerase and related proteins [Carbohydrate transport and metabolism]; Region: FucI; COG2407
502801002873	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cd00578
502801002874	hexamer (dimer of trimers) interface [polypeptide binding]; other site
502801002875	substrate binding site [chemical binding]; other site
502801002876	trimer interface [polypeptide binding]; other site
502801002877	Mn binding site [ion binding]; other site
502801002878	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801002879	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
502801002880	MarR family; Region: MarR_2; cl17246
502801002881	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
502801002882	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801002883	putative MFS family transporter protein; Provisional; Region: PRK03633
502801002884	putative substrate translocation pore; other site
502801002885	hypothetical protein; Validated; Region: PRK03661
502801002886	recombinase A; Provisional; Region: recA; PRK09354
502801002887	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
502801002888	hexamer interface [polypeptide binding]; other site
502801002889	Walker A motif; other site
502801002890	ATP binding site [chemical binding]; other site
502801002891	Walker B motif; other site
502801002892	recombination regulator RecX; Reviewed; Region: recX; PRK00117
502801002893	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
502801002894	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
502801002895	motif 1; other site
502801002896	active site
502801002897	motif 2; other site
502801002898	motif 3; other site
502801002899	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
502801002900	DHHA1 domain; Region: DHHA1; pfam02272
502801002901	carbon storage regulator; Provisional; Region: PRK01712
502801002902	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
502801002903	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801002904	motif II; other site
502801002905	Predicted membrane protein [Function unknown]; Region: COG1238
502801002906	glutamate--cysteine ligase; Provisional; Region: PRK02107
502801002907	S-ribosylhomocysteinase; Provisional; Region: PRK02260
502801002908	hypothetical protein; Provisional; Region: PRK11573
502801002909	Domain of unknown function DUF21; Region: DUF21; pfam01595
502801002910	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
502801002911	Transporter associated domain; Region: CorC_HlyC; smart01091
502801002912	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
502801002913	signal recognition particle protein; Provisional; Region: PRK10867
502801002914	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
502801002915	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
502801002916	P loop; other site
502801002917	GTP binding site [chemical binding]; other site
502801002918	Signal peptide binding domain; Region: SRP_SPB; pfam02978
502801002919	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
502801002920	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
502801002921	RimM N-terminal domain; Region: RimM; pfam01782
502801002922	PRC-barrel domain; Region: PRC; pfam05239
502801002923	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
502801002924	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
502801002925	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
502801002926	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
502801002927	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
502801002928	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
502801002929	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801002930	active site
502801002931	phosphorylation site [posttranslational modification]
502801002932	intermolecular recognition site; other site
502801002933	dimerization interface [polypeptide binding]; other site
502801002934	LytTr DNA-binding domain; Region: LytTR; pfam04397
502801002935	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
502801002936	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
502801002937	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
502801002938	Chorismate mutase type II; Region: CM_2; cl00693
502801002939	prephenate dehydrogenase; Validated; Region: PRK08507
502801002940	transposase/IS protein; Provisional; Region: PRK09183
502801002941	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801002942	Walker A motif; other site
502801002943	ATP binding site [chemical binding]; other site
502801002944	Walker B motif; other site
502801002945	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
502801002946	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
502801002947	DNA-binding interface [nucleotide binding]; DNA binding site
502801002948	Integrase core domain; Region: rve; pfam00665
502801002949	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
502801002950	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
502801002951	Prephenate dehydratase; Region: PDT; pfam00800
502801002952	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
502801002953	putative L-Phe binding site [chemical binding]; other site
502801002954	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
502801002955	30S subunit binding site; other site
502801002956	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
502801002957	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
502801002958	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
502801002959	RNA binding surface [nucleotide binding]; other site
502801002960	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
502801002961	active site
502801002962	hypothetical protein; Provisional; Region: PRK10723
502801002963	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
502801002964	protein disaggregation chaperone; Provisional; Region: PRK10865
502801002965	Clp amino terminal domain; Region: Clp_N; pfam02861
502801002966	Clp amino terminal domain; Region: Clp_N; pfam02861
502801002967	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801002968	Walker A motif; other site
502801002969	ATP binding site [chemical binding]; other site
502801002970	Walker B motif; other site
502801002971	arginine finger; other site
502801002972	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801002973	Walker A motif; other site
502801002974	ATP binding site [chemical binding]; other site
502801002975	Walker B motif; other site
502801002976	arginine finger; other site
502801002977	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
502801002978	lipoprotein; Provisional; Region: PRK10759
502801002979	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
502801002980	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
502801002981	domain interface [polypeptide binding]; other site
502801002982	putative active site [active]
502801002983	catalytic site [active]
502801002984	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
502801002985	domain interface [polypeptide binding]; other site
502801002986	putative active site [active]
502801002987	catalytic site [active]
502801002988	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
502801002989	CoA binding domain; Region: CoA_binding_2; pfam13380
502801002990	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
502801002991	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
502801002992	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
502801002993	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
502801002994	Coenzyme A binding pocket [chemical binding]; other site
502801002995	Uncharacterized conserved protein [Function unknown]; Region: COG3148
502801002996	thioredoxin 2; Provisional; Region: PRK10996
502801002997	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
502801002998	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
502801002999	catalytic residues [active]
502801003000	putative methyltransferase; Provisional; Region: PRK10864
502801003001	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
502801003002	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
502801003003	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
502801003004	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801003005	putative substrate translocation pore; other site
502801003006	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801003007	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
502801003008	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801003009	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801003010	transcriptional repressor MprA; Provisional; Region: PRK10870
502801003011	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
502801003012	putative L-valine exporter; Provisional; Region: PRK10408
502801003013	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
502801003014	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801003015	putative substrate translocation pore; other site
502801003016	Protein of unknown function (DUF3225); Region: DUF3225; pfam11533
502801003017	amidase; Provisional; Region: PRK09201
502801003018	Amidase; Region: Amidase; cl11426
502801003019	Protein of unknown function (DUF4089); Region: DUF4089; pfam13318
502801003020	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
502801003021	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
502801003022	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
502801003023	putative active site [active]
502801003024	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
502801003025	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801003026	substrate binding pocket [chemical binding]; other site
502801003027	membrane-bound complex binding site; other site
502801003028	hinge residues; other site
502801003029	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
502801003030	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801003031	dimer interface [polypeptide binding]; other site
502801003032	conserved gate region; other site
502801003033	putative PBP binding loops; other site
502801003034	ABC-ATPase subunit interface; other site
502801003035	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801003036	dimer interface [polypeptide binding]; other site
502801003037	conserved gate region; other site
502801003038	putative PBP binding loops; other site
502801003039	ABC-ATPase subunit interface; other site
502801003040	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
502801003041	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
502801003042	Walker A/P-loop; other site
502801003043	ATP binding site [chemical binding]; other site
502801003044	Q-loop/lid; other site
502801003045	ABC transporter signature motif; other site
502801003046	Walker B; other site
502801003047	D-loop; other site
502801003048	H-loop/switch region; other site
502801003049	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
502801003050	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801003051	catalytic residue [active]
502801003052	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
502801003053	allantoate amidohydrolase; Reviewed; Region: PRK09290
502801003054	active site
502801003055	metal binding site [ion binding]; metal-binding site
502801003056	dimer interface [polypeptide binding]; other site
502801003057	C-N hydrolase family amidase; Provisional; Region: PRK10438
502801003058	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
502801003059	active site
502801003060	catalytic triad [active]
502801003061	dimer interface [polypeptide binding]; other site
502801003062	methionine aminotransferase; Validated; Region: PRK09082
502801003063	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801003064	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801003065	homodimer interface [polypeptide binding]; other site
502801003066	catalytic residue [active]
502801003067	methylthioribulose-1-phosphate dehydratase; Provisional; Region: PRK09220
502801003068	intersubunit interface [polypeptide binding]; other site
502801003069	active site
502801003070	Zn2+ binding site [ion binding]; other site
502801003071	2,3-diketo-5-methylthio-1-phosphopentane phosphatase; Region: enolase-ppase; TIGR01691
502801003072	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
502801003073	motif II; other site
502801003074	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
502801003075	Cupin domain; Region: Cupin_2; cl17218
502801003076	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
502801003077	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
502801003078	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
502801003079	Phosphotransferase enzyme family; Region: APH; pfam01636
502801003080	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
502801003081	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
502801003082	filamentous hemagglutinin family N-terminal domain; Region: adhes_NPXG; TIGR01901
502801003083	Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914
502801003084	Adhesin biosynthesis transcription regulatory protein; Region: PapB; cl04012
502801003085	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
502801003086	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
502801003087	active site
502801003088	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
502801003089	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
502801003090	dimer interface [polypeptide binding]; other site
502801003091	active site
502801003092	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
502801003093	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
502801003094	putative active site [active]
502801003095	putative dimer interface [polypeptide binding]; other site
502801003096	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
502801003097	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
502801003098	Na(+)-translocating NADH-quinone reductase subunit A; Provisional; Region: PRK05352
502801003099	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
502801003100	E3 interaction surface; other site
502801003101	lipoyl attachment site [posttranslational modification]; other site
502801003102	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
502801003103	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK05349
502801003104	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC [Energy production and conversion]; Region: NqrC; COG2869
502801003105	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
502801003106	Na(+)-translocating NADH-quinone reductase subunit D; Validated; Region: PRK09292
502801003107	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK02830
502801003108	Na(+)-translocating NADH-quinone reductase subunit F; Provisional; Region: PRK05464
502801003109	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
502801003110	catalytic loop [active]
502801003111	iron binding site [ion binding]; other site
502801003112	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
502801003113	FAD binding pocket [chemical binding]; other site
502801003114	FAD binding motif [chemical binding]; other site
502801003115	phosphate binding motif [ion binding]; other site
502801003116	beta-alpha-beta structure motif; other site
502801003117	NAD binding pocket [chemical binding]; other site
502801003118	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
502801003119	ApbE family; Region: ApbE; pfam02424
502801003120	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2991
502801003121	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
502801003122	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial protein Rv2277c and similar proteins; Region: GDPD_Rv2277c_like; cd08580
502801003123	putative active site [active]
502801003124	catalytic site [active]
502801003125	putative metal binding site [ion binding]; other site
502801003126	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
502801003127	active site
502801003128	DNA polymerase IV; Validated; Region: PRK02406
502801003129	DNA binding site [nucleotide binding]
502801003130	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
502801003131	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
502801003132	metal binding site [ion binding]; metal-binding site
502801003133	dimer interface [polypeptide binding]; other site
502801003134	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801003135	LysR substrate binding domain; Region: LysR_substrate; pfam03466
502801003136	dimerization interface [polypeptide binding]; other site
502801003137	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3397
502801003138	Chitin binding domain; Region: Chitin_bind_3; pfam03067
502801003139	PKD domain; Region: PKD; pfam00801
502801003140	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
502801003141	active site
502801003142	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
502801003143	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
502801003144	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
502801003145	gamma-glutamyl kinase; Provisional; Region: PRK05429
502801003146	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
502801003147	nucleotide binding site [chemical binding]; other site
502801003148	homotetrameric interface [polypeptide binding]; other site
502801003149	putative phosphate binding site [ion binding]; other site
502801003150	putative allosteric binding site; other site
502801003151	PUA domain; Region: PUA; pfam01472
502801003152	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
502801003153	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
502801003154	putative catalytic cysteine [active]
502801003155	Flagellar regulator YcgR; Region: YcgR; pfam07317
502801003156	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
502801003157	PilZ domain; Region: PilZ; pfam07238
502801003158	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801003159	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
502801003160	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
502801003161	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
502801003162	ADP binding site [chemical binding]; other site
502801003163	magnesium binding site [ion binding]; other site
502801003164	putative shikimate binding site; other site
502801003165	hypothetical protein; Provisional; Region: PRK10579
502801003166	recombination associated protein; Reviewed; Region: rdgC; PRK00321
502801003167	fructokinase; Reviewed; Region: PRK09557
502801003168	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
502801003169	nucleotide binding site [chemical binding]; other site
502801003170	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801003171	AAA domain; Region: AAA_23; pfam13476
502801003172	Walker A/P-loop; other site
502801003173	ATP binding site [chemical binding]; other site
502801003174	Q-loop/lid; other site
502801003175	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801003176	ABC transporter signature motif; other site
502801003177	Walker B; other site
502801003178	D-loop; other site
502801003179	H-loop/switch region; other site
502801003180	exonuclease subunit SbcD; Provisional; Region: PRK10966
502801003181	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
502801003182	active site
502801003183	metal binding site [ion binding]; metal-binding site
502801003184	DNA binding site [nucleotide binding]
502801003185	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
502801003186	transcriptional regulator PhoB; Provisional; Region: PRK10161
502801003187	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801003188	active site
502801003189	phosphorylation site [posttranslational modification]
502801003190	intermolecular recognition site; other site
502801003191	dimerization interface [polypeptide binding]; other site
502801003192	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801003193	DNA binding site [nucleotide binding]
502801003194	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
502801003195	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
502801003196	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
502801003197	putative active site [active]
502801003198	heme pocket [chemical binding]; other site
502801003199	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801003200	dimer interface [polypeptide binding]; other site
502801003201	phosphorylation site [posttranslational modification]
502801003202	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801003203	ATP binding site [chemical binding]; other site
502801003204	Mg2+ binding site [ion binding]; other site
502801003205	G-X-G motif; other site
502801003206	PBP superfamily domain; Region: PBP_like_2; cl17296
502801003207	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
502801003208	putative proline-specific permease; Provisional; Region: proY; PRK10580
502801003209	Spore germination protein; Region: Spore_permease; cl17796
502801003210	maltodextrin glucosidase; Provisional; Region: PRK10785
502801003211	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
502801003212	homodimer interface [polypeptide binding]; other site
502801003213	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
502801003214	active site
502801003215	homodimer interface [polypeptide binding]; other site
502801003216	catalytic site [active]
502801003217	carbonyl reductase sniffer-like, classical (c) SDRs; Region: carb_red_sniffer_like_SDR_c; cd05325
502801003218	C factor cell-cell signaling protein; Provisional; Region: PRK09009
502801003219	NADP binding site [chemical binding]; other site
502801003220	homodimer interface [polypeptide binding]; other site
502801003221	active site
502801003222	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
502801003223	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
502801003224	peroxidase; Provisional; Region: PRK15000
502801003225	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
502801003226	dimer interface [polypeptide binding]; other site
502801003227	decamer (pentamer of dimers) interface [polypeptide binding]; other site
502801003228	catalytic triad [active]
502801003229	peroxidatic and resolving cysteines [active]
502801003230	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3124
502801003231	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
502801003232	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
502801003233	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
502801003234	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
502801003235	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
502801003236	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
502801003237	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
502801003238	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
502801003239	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
502801003240	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
502801003241	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
502801003242	Protein export membrane protein; Region: SecD_SecF; pfam02355
502801003243	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
502801003244	ATP cone domain; Region: ATP-cone; pfam03477
502801003245	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
502801003246	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
502801003247	catalytic motif [active]
502801003248	Zn binding site [ion binding]; other site
502801003249	RibD C-terminal domain; Region: RibD_C; cl17279
502801003250	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
502801003251	homopentamer interface [polypeptide binding]; other site
502801003252	active site
502801003253	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
502801003254	putative RNA binding site [nucleotide binding]; other site
502801003255	thiamine monophosphate kinase; Provisional; Region: PRK05731
502801003256	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
502801003257	ATP binding site [chemical binding]; other site
502801003258	dimerization interface [polypeptide binding]; other site
502801003259	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
502801003260	tetramer interfaces [polypeptide binding]; other site
502801003261	binuclear metal-binding site [ion binding]; other site
502801003262	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
502801003263	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
502801003264	TPP-binding site; other site
502801003265	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
502801003266	PYR/PP interface [polypeptide binding]; other site
502801003267	dimer interface [polypeptide binding]; other site
502801003268	TPP binding site [chemical binding]; other site
502801003269	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
502801003270	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
502801003271	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
502801003272	substrate binding pocket [chemical binding]; other site
502801003273	chain length determination region; other site
502801003274	substrate-Mg2+ binding site; other site
502801003275	catalytic residues [active]
502801003276	aspartate-rich region 1; other site
502801003277	active site lid residues [active]
502801003278	aspartate-rich region 2; other site
502801003279	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
502801003280	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
502801003281	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
502801003282	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
502801003283	Ligand Binding Site [chemical binding]; other site
502801003284	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
502801003285	active site residue [active]
502801003286	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
502801003287	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
502801003288	conserved cys residue [active]
502801003289	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
502801003290	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
502801003291	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
502801003292	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
502801003293	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
502801003294	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801003295	Major Facilitator Superfamily; Region: MFS_1; pfam07690
502801003296	putative substrate translocation pore; other site
502801003297	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
502801003298	UbiA prenyltransferase family; Region: UbiA; pfam01040
502801003299	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
502801003300	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
502801003301	Subunit I/III interface [polypeptide binding]; other site
502801003302	Subunit III/IV interface [polypeptide binding]; other site
502801003303	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
502801003304	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
502801003305	D-pathway; other site
502801003306	Putative ubiquinol binding site [chemical binding]; other site
502801003307	Low-spin heme (heme b) binding site [chemical binding]; other site
502801003308	Putative water exit pathway; other site
502801003309	Binuclear center (heme o3/CuB) [ion binding]; other site
502801003310	K-pathway; other site
502801003311	Putative proton exit pathway; other site
502801003312	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
502801003313	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
502801003314	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
502801003315	hypothetical protein; Provisional; Region: PRK11528
502801003316	muropeptide transporter; Reviewed; Region: ampG; PRK11902
502801003317	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801003318	putative substrate translocation pore; other site
502801003319	hypothetical protein; Provisional; Region: PRK11627
502801003320	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
502801003321	transcriptional regulator BolA; Provisional; Region: PRK11628
502801003322	trigger factor; Provisional; Region: tig; PRK01490
502801003323	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
502801003324	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
502801003325	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
502801003326	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
502801003327	oligomer interface [polypeptide binding]; other site
502801003328	active site residues [active]
502801003329	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
502801003330	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
502801003331	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801003332	Walker A motif; other site
502801003333	ATP binding site [chemical binding]; other site
502801003334	Walker B motif; other site
502801003335	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
502801003336	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
502801003337	Found in ATP-dependent protease La (LON); Region: LON; smart00464
502801003338	Found in ATP-dependent protease La (LON); Region: LON; smart00464
502801003339	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801003340	Walker A motif; other site
502801003341	ATP binding site [chemical binding]; other site
502801003342	Walker B motif; other site
502801003343	arginine finger; other site
502801003344	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
502801003345	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
502801003346	IHF dimer interface [polypeptide binding]; other site
502801003347	IHF - DNA interface [nucleotide binding]; other site
502801003348	periplasmic folding chaperone; Provisional; Region: PRK10788
502801003349	SurA N-terminal domain; Region: SurA_N_3; cl07813
502801003350	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
502801003351	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
502801003352	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
502801003353	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
502801003354	active site
502801003355	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
502801003356	Ligand Binding Site [chemical binding]; other site
502801003357	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
502801003358	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
502801003359	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
502801003360	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
502801003361	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801003362	active site
502801003363	motif I; other site
502801003364	motif II; other site
502801003365	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
502801003366	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
502801003367	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801003368	catalytic residue [active]
502801003369	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
502801003370	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
502801003371	putative DNA binding site [nucleotide binding]; other site
502801003372	putative Zn2+ binding site [ion binding]; other site
502801003373	AsnC family; Region: AsnC_trans_reg; pfam01037
502801003374	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
502801003375	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801003376	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801003377	Walker A/P-loop; other site
502801003378	ATP binding site [chemical binding]; other site
502801003379	Q-loop/lid; other site
502801003380	ABC transporter signature motif; other site
502801003381	Walker B; other site
502801003382	D-loop; other site
502801003383	H-loop/switch region; other site
502801003384	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
502801003385	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801003386	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
502801003387	Walker A/P-loop; other site
502801003388	ATP binding site [chemical binding]; other site
502801003389	Q-loop/lid; other site
502801003390	ABC transporter signature motif; other site
502801003391	Walker B; other site
502801003392	D-loop; other site
502801003393	H-loop/switch region; other site
502801003394	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
502801003395	Nitrogen regulatory protein P-II; Region: P-II; smart00938
502801003396	ammonium transporter; Provisional; Region: PRK10666
502801003397	acyl-CoA thioesterase II; Provisional; Region: PRK10526
502801003398	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
502801003399	active site
502801003400	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
502801003401	catalytic triad [active]
502801003402	dimer interface [polypeptide binding]; other site
502801003403	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
502801003404	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
502801003405	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
502801003406	DNA binding site [nucleotide binding]
502801003407	active site
502801003408	gene expression modulator; Provisional; Region: PRK10945
502801003409	Hha toxicity attenuator; Provisional; Region: PRK10667
502801003410	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
502801003411	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
502801003412	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
502801003413	Protein export membrane protein; Region: SecD_SecF; cl14618
502801003414	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
502801003415	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801003416	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801003417	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
502801003418	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
502801003419	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
502801003420	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
502801003421	hypothetical protein; Provisional; Region: PRK11281
502801003422	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
502801003423	Mechanosensitive ion channel; Region: MS_channel; pfam00924
502801003424	hypothetical protein; Provisional; Region: PRK11038
502801003425	Primosomal replication protein priB and priC; Region: priB_priC; pfam07445
502801003426	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
502801003427	active site
502801003428	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
502801003429	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801003430	Walker A motif; other site
502801003431	ATP binding site [chemical binding]; other site
502801003432	Walker B motif; other site
502801003433	arginine finger; other site
502801003434	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
502801003435	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
502801003436	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
502801003437	hypothetical protein; Validated; Region: PRK00153
502801003438	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
502801003439	RecR protein; Region: RecR; pfam02132
502801003440	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
502801003441	putative active site [active]
502801003442	putative metal-binding site [ion binding]; other site
502801003443	tetramer interface [polypeptide binding]; other site
502801003444	heat shock protein 90; Provisional; Region: PRK05218
502801003445	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801003446	ATP binding site [chemical binding]; other site
502801003447	Mg2+ binding site [ion binding]; other site
502801003448	G-X-G motif; other site
502801003449	adenylate kinase; Reviewed; Region: adk; PRK00279
502801003450	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
502801003451	AMP-binding site [chemical binding]; other site
502801003452	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
502801003453	ferrochelatase; Reviewed; Region: hemH; PRK00035
502801003454	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
502801003455	C-terminal domain interface [polypeptide binding]; other site
502801003456	active site
502801003457	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
502801003458	active site
502801003459	N-terminal domain interface [polypeptide binding]; other site
502801003460	CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609
502801003461	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
502801003462	catalytic loop [active]
502801003463	iron binding site [ion binding]; other site
502801003464	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
502801003465	FAD binding pocket [chemical binding]; other site
502801003466	FAD binding motif [chemical binding]; other site
502801003467	phosphate binding motif [ion binding]; other site
502801003468	beta-alpha-beta structure motif; other site
502801003469	NAD binding pocket [chemical binding]; other site
502801003470	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
502801003471	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
502801003472	substrate binding site; other site
502801003473	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
502801003474	CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252
502801003475	NAD binding site [chemical binding]; other site
502801003476	homotetramer interface [polypeptide binding]; other site
502801003477	homodimer interface [polypeptide binding]; other site
502801003478	substrate binding site [chemical binding]; other site
502801003479	active site
502801003480	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
502801003481	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
502801003482	inhibitor-cofactor binding pocket; inhibition site
502801003483	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801003484	catalytic residue [active]
502801003485	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801003486	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
502801003487	NAD(P) binding site [chemical binding]; other site
502801003488	active site
502801003489	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
502801003490	Protoporphyrinogen oxidase [Coenzyme metabolism]; Region: HemY; COG1232
502801003491	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
502801003492	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
502801003493	active site
502801003494	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
502801003495	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
502801003496	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
502801003497	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
502801003498	putative ADP-binding pocket [chemical binding]; other site
502801003499	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
502801003500	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801003501	NAD(P) binding site [chemical binding]; other site
502801003502	active site
502801003503	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
502801003504	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
502801003505	NADP-binding site; other site
502801003506	homotetramer interface [polypeptide binding]; other site
502801003507	substrate binding site [chemical binding]; other site
502801003508	homodimer interface [polypeptide binding]; other site
502801003509	active site
502801003510	Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only]; Region: COG2605
502801003511	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
502801003512	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
502801003513	dimer interface [polypeptide binding]; other site
502801003514	active site
502801003515	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
502801003516	WcbM_like is a subfamily of nucleotidyl transferases; Region: NTP_transferase_WcbM_like; cd06915
502801003517	Substrate binding site; other site
502801003518	Mg++ binding site; other site
502801003519	metal-binding site
502801003520	Mg++ binding site; other site
502801003521	metal-binding site
502801003522	Histidinol phosphatase and related phosphatases [Amino acid transport and metabolism]; Region: HisB; COG0241
502801003523	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801003524	active site
502801003525	motif I; other site
502801003526	motif II; other site
502801003527	LPS O-antigen length regulator; Provisional; Region: PRK10381
502801003528	Chain length determinant protein; Region: Wzz; pfam02706
502801003529	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
502801003530	inosine/guanosine kinase; Provisional; Region: PRK15074
502801003531	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
502801003532	substrate binding site [chemical binding]; other site
502801003533	ATP binding site [chemical binding]; other site
502801003534	putative cation:proton antiport protein; Provisional; Region: PRK10669
502801003535	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
502801003536	TrkA-N domain; Region: TrkA_N; pfam02254
502801003537	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801003538	Major Facilitator Superfamily; Region: MFS_1; pfam07690
502801003539	putative substrate translocation pore; other site
502801003540	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801003541	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
502801003542	putative deacylase active site [active]
502801003543	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
502801003544	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
502801003545	metal-binding site [ion binding]
502801003546	copper exporting ATPase; Provisional; Region: copA; PRK10671
502801003547	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
502801003548	metal-binding site [ion binding]
502801003549	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
502801003550	metal-binding site [ion binding]
502801003551	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
502801003552	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801003553	motif II; other site
502801003554	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
502801003555	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
502801003556	DNA binding residues [nucleotide binding]
502801003557	dimer interface [polypeptide binding]; other site
502801003558	copper binding site [ion binding]; other site
502801003559	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
502801003560	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
502801003561	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
502801003562	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
502801003563	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
502801003564	oxidoreductase; Provisional; Region: PRK08017
502801003565	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801003566	NAD(P) binding site [chemical binding]; other site
502801003567	active site
502801003568	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
502801003569	active site
502801003570	catalytic triad [active]
502801003571	oxyanion hole [active]
502801003572	switch loop; other site
502801003573	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
502801003574	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
502801003575	Walker A/P-loop; other site
502801003576	ATP binding site [chemical binding]; other site
502801003577	Q-loop/lid; other site
502801003578	ABC transporter signature motif; other site
502801003579	Walker B; other site
502801003580	D-loop; other site
502801003581	H-loop/switch region; other site
502801003582	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
502801003583	FtsX-like permease family; Region: FtsX; pfam02687
502801003584	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
502801003585	ATP-grasp domain; Region: ATP-grasp; pfam02222
502801003586	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
502801003587	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
502801003588	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
502801003589	putative active site [active]
502801003590	putative metal binding site [ion binding]; other site
502801003591	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
502801003592	substrate binding site [chemical binding]; other site
502801003593	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
502801003594	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
502801003595	active site
502801003596	HIGH motif; other site
502801003597	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
502801003598	KMSKS motif; other site
502801003599	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
502801003600	tRNA binding surface [nucleotide binding]; other site
502801003601	anticodon binding site; other site
502801003602	ribosome-associated protein; Provisional; Region: PRK11507
502801003603	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
502801003604	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
502801003605	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
502801003606	homodimer interface [polypeptide binding]; other site
502801003607	NADP binding site [chemical binding]; other site
502801003608	substrate binding site [chemical binding]; other site
502801003609	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
502801003610	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
502801003611	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
502801003612	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
502801003613	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
502801003614	putative acyl-acceptor binding pocket; other site
502801003615	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
502801003616	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
502801003617	Putative methyltransferase; Region: Methyltransf_20; pfam12147
502801003618	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
502801003619	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
502801003620	active site
502801003621	Predicted protein-tyrosine phosphatase [Signal transduction mechanisms]; Region: CDC14; COG2453
502801003622	active site
502801003623	catalytic residues [active]
502801003624	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801003625	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801003626	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
502801003627	putative effector binding pocket; other site
502801003628	putative dimerization interface [polypeptide binding]; other site
502801003629	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
502801003630	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
502801003631	active site
502801003632	catalytic tetrad [active]
502801003633	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
502801003634	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
502801003635	active site
502801003636	catalytic tetrad [active]
502801003637	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
502801003638	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
502801003639	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
502801003640	Uncharacterized membrane-anchored protein [Function unknown]; Region: COG4929
502801003641	Predicted membrane protein (DUF2157); Region: DUF2157; pfam09925
502801003642	Predicted membrane protein [Function unknown]; Region: COG4984
502801003643	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
502801003644	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
502801003645	RNA binding surface [nucleotide binding]; other site
502801003646	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
502801003647	probable active site [active]
502801003648	Uncharacterized conserved protein [Function unknown]; Region: COG2850
502801003649	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
502801003650	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
502801003651	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
502801003652	Autotransporter beta-domain; Region: Autotransporter; pfam03797
502801003653	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
502801003654	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
502801003655	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
502801003656	Winged helix-turn-helix DNA-binding; Region: HTH_35; pfam13693
502801003657	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
502801003658	Transglycosylase; Region: Transgly; pfam00912
502801003659	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
502801003660	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
502801003661	IgD-like repeat domain of mycobacterial L,D-transpeptidases; Region: LDT_IgD_like; cl17506
502801003662	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
502801003663	MG2 domain; Region: A2M_N; pfam01835
502801003664	Alpha-2-macroglobulin family; Region: A2M; pfam00207
502801003665	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
502801003666	surface patch; other site
502801003667	thioester region; other site
502801003668	specificity defining residues; other site
502801003669	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
502801003670	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
502801003671	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
502801003672	putative active site [active]
502801003673	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
502801003674	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
502801003675	tetrameric interface [polypeptide binding]; other site
502801003676	NAD binding site [chemical binding]; other site
502801003677	catalytic residues [active]
502801003678	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
502801003679	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
502801003680	PYR/PP interface [polypeptide binding]; other site
502801003681	dimer interface [polypeptide binding]; other site
502801003682	TPP binding site [chemical binding]; other site
502801003683	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
502801003684	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
502801003685	TPP-binding site; other site
502801003686	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
502801003687	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
502801003688	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
502801003689	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
502801003690	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
502801003691	ligand binding site [chemical binding]; other site
502801003692	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801003693	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801003694	Walker A/P-loop; other site
502801003695	ATP binding site [chemical binding]; other site
502801003696	Q-loop/lid; other site
502801003697	ABC transporter signature motif; other site
502801003698	Walker B; other site
502801003699	D-loop; other site
502801003700	H-loop/switch region; other site
502801003701	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801003702	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801003703	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801003704	TM-ABC transporter signature motif; other site
502801003705	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
502801003706	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
502801003707	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
502801003708	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
502801003709	substrate binding site [chemical binding]; other site
502801003710	ATP binding site [chemical binding]; other site
502801003711	Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863
502801003712	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3892
502801003713	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
502801003714	Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism]; Region: IolB; COG3718
502801003715	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801003716	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
502801003717	ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; Region: ABCC_ATM1_transporter; cd03253
502801003718	Walker A/P-loop; other site
502801003719	ATP binding site [chemical binding]; other site
502801003720	Q-loop/lid; other site
502801003721	ABC transporter signature motif; other site
502801003722	Walker B; other site
502801003723	D-loop; other site
502801003724	H-loop/switch region; other site
502801003725	Uncharacterized conserved protein [Function unknown]; Region: COG1359
502801003726	Glycogen synthesis protein; Region: GlgS; cl11663
502801003727	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
502801003728	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
502801003729	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801003730	DNA binding residues [nucleotide binding]
502801003731	dimerization interface [polypeptide binding]; other site
502801003732	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
502801003733	DNA-binding site [nucleotide binding]; DNA binding site
502801003734	RNA-binding motif; other site
502801003735	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
502801003736	DNA-binding site [nucleotide binding]; DNA binding site
502801003737	RNA-binding motif; other site
502801003738	chromosome condensation membrane protein; Provisional; Region: PRK14196
502801003739	twin arginine translocase protein A; Validated; Region: tatE; PRK01614
502801003740	lipoyl synthase; Provisional; Region: PRK05481
502801003741	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801003742	FeS/SAM binding site; other site
502801003743	lipoate-protein ligase B; Provisional; Region: PRK14342
502801003744	hypothetical protein; Provisional; Region: PRK04998
502801003745	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
502801003746	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
502801003747	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
502801003748	rare lipoprotein A; Provisional; Region: PRK10672
502801003749	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
502801003750	Sporulation related domain; Region: SPOR; pfam05036
502801003751	cell wall shape-determining protein; Provisional; Region: PRK10794
502801003752	penicillin-binding protein 2; Provisional; Region: PRK10795
502801003753	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
502801003754	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
502801003755	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
502801003756	ribosome-associated protein; Provisional; Region: PRK11538
502801003757	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
502801003758	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
502801003759	active site
502801003760	(T/H)XGH motif; other site
502801003761	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
502801003762	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
502801003763	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
502801003764	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
502801003765	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
502801003766	HIGH motif; other site
502801003767	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
502801003768	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
502801003769	active site
502801003770	KMSKS motif; other site
502801003771	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
502801003772	tRNA binding surface [nucleotide binding]; other site
502801003773	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
502801003774	hypothetical protein; Provisional; Region: PRK11032
502801003775	Flagella accessory protein C (FlaC); Region: FlaC_arch; cl10488
502801003776	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
502801003777	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
502801003778	Walker A/P-loop; other site
502801003779	ATP binding site [chemical binding]; other site
502801003780	Q-loop/lid; other site
502801003781	ABC transporter signature motif; other site
502801003782	Walker B; other site
502801003783	D-loop; other site
502801003784	H-loop/switch region; other site
502801003785	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
502801003786	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801003787	dimer interface [polypeptide binding]; other site
502801003788	conserved gate region; other site
502801003789	putative PBP binding loops; other site
502801003790	ABC-ATPase subunit interface; other site
502801003791	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
502801003792	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801003793	dimer interface [polypeptide binding]; other site
502801003794	conserved gate region; other site
502801003795	putative PBP binding loops; other site
502801003796	ABC-ATPase subunit interface; other site
502801003797	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
502801003798	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801003799	substrate binding pocket [chemical binding]; other site
502801003800	membrane-bound complex binding site; other site
502801003801	hinge residues; other site
502801003802	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
502801003803	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
502801003804	putative active site [active]
502801003805	catalytic triad [active]
502801003806	putative dimer interface [polypeptide binding]; other site
502801003807	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
502801003808	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
502801003809	Transporter associated domain; Region: CorC_HlyC; smart01091
502801003810	metal-binding heat shock protein; Provisional; Region: PRK00016
502801003811	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
502801003812	PhoH-like protein; Region: PhoH; pfam02562
502801003813	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
502801003814	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
502801003815	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801003816	FeS/SAM binding site; other site
502801003817	TRAM domain; Region: TRAM; pfam01938
502801003818	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
502801003819	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
502801003820	asparagine synthetase B; Provisional; Region: asnB; PRK09431
502801003821	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
502801003822	active site
502801003823	dimer interface [polypeptide binding]; other site
502801003824	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
502801003825	Ligand Binding Site [chemical binding]; other site
502801003826	Molecular Tunnel; other site
502801003827	UMP phosphatase; Provisional; Region: PRK10444
502801003828	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801003829	active site
502801003830	motif I; other site
502801003831	motif II; other site
502801003832	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801003833	MarR family; Region: MarR; pfam01047
502801003834	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
502801003835	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
502801003836	nucleotide binding site [chemical binding]; other site
502801003837	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
502801003838	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
502801003839	active site
502801003840	dimer interface [polypeptide binding]; other site
502801003841	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
502801003842	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
502801003843	active site
502801003844	trimer interface [polypeptide binding]; other site
502801003845	allosteric site; other site
502801003846	active site lid [active]
502801003847	hexamer (dimer of trimers) interface [polypeptide binding]; other site
502801003848	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
502801003849	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
502801003850	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
502801003851	active site turn [active]
502801003852	phosphorylation site [posttranslational modification]
502801003853	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
502801003854	HPr interaction site; other site
502801003855	glycerol kinase (GK) interaction site [polypeptide binding]; other site
502801003856	active site
502801003857	phosphorylation site [posttranslational modification]
502801003858	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
502801003859	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
502801003860	active site
502801003861	HIGH motif; other site
502801003862	nucleotide binding site [chemical binding]; other site
502801003863	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
502801003864	KMSKS motif; other site
502801003865	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
502801003866	outer membrane porin, OprD family; Region: OprD; pfam03573
502801003867	Putative carbohydrate binding domain; Region: CHB_HEX; smart01081
502801003868	N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism]; Region: Chb; COG3525
502801003869	Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838
502801003870	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a...; Region: GH20_Sm-chitobiase-like; cd06569
502801003871	active site
502801003872	C-terminal Early set domain associated with the catalytic domain of chitobiase (also called N-acetylglucosaminidase); Region: E_set_Chitobiase_C; cd02847
502801003873	ferric uptake regulator; Provisional; Region: fur; PRK09462
502801003874	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
502801003875	metal binding site 2 [ion binding]; metal-binding site
502801003876	putative DNA binding helix; other site
502801003877	metal binding site 1 [ion binding]; metal-binding site
502801003878	dimer interface [polypeptide binding]; other site
502801003879	structural Zn2+ binding site [ion binding]; other site
502801003880	flavodoxin FldA; Validated; Region: PRK09267
502801003881	LexA regulated protein; Provisional; Region: PRK11675
502801003882	acyl-CoA esterase; Provisional; Region: PRK10673
502801003883	PGAP1-like protein; Region: PGAP1; pfam07819
502801003884	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
502801003885	active site
502801003886	Int/Topo IB signature motif; other site
502801003887	Transposase; Region: HTH_Tnp_1; pfam01527
502801003888	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
502801003889	Methyltransferase domain; Region: Methyltransf_27; pfam13708
502801003890	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
502801003891	transposase/IS protein; Provisional; Region: PRK09183
502801003892	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801003893	Walker A motif; other site
502801003894	ATP binding site [chemical binding]; other site
502801003895	Walker B motif; other site
502801003896	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
502801003897	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
502801003898	DNA-binding interface [nucleotide binding]; DNA binding site
502801003899	Integrase core domain; Region: rve; pfam00665
502801003900	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
502801003901	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
502801003902	MPN+ (JAMM) motif; other site
502801003903	Zinc-binding site [ion binding]; other site
502801003904	Domain of unknown function (DUF932); Region: DUF932; pfam06067
502801003905	YfjP GTPase; Region: YfjP; cd11383
502801003906	G1 box; other site
502801003907	GTP/Mg2+ binding site [chemical binding]; other site
502801003908	Switch I region; other site
502801003909	G2 box; other site
502801003910	Switch II region; other site
502801003911	G3 box; other site
502801003912	G4 box; other site
502801003913	G5 box; other site
502801003914	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
502801003915	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
502801003916	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
502801003917	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
502801003918	Predicted ATPase [General function prediction only]; Region: COG5293
502801003919	integrase; Provisional; Region: PRK09692
502801003920	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
502801003921	active site
502801003922	Int/Topo IB signature motif; other site
502801003923	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
502801003924	SmpB-tmRNA interface; other site
502801003925	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
502801003926	putative coenzyme Q binding site [chemical binding]; other site
502801003927	hypothetical protein; Validated; Region: PRK01777
502801003928	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
502801003929	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
502801003930	recombination and repair protein; Provisional; Region: PRK10869
502801003931	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
502801003932	Walker A/P-loop; other site
502801003933	ATP binding site [chemical binding]; other site
502801003934	Q-loop/lid; other site
502801003935	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
502801003936	Q-loop/lid; other site
502801003937	ABC transporter signature motif; other site
502801003938	Walker B; other site
502801003939	D-loop; other site
502801003940	H-loop/switch region; other site
502801003941	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
502801003942	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
502801003943	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
502801003944	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
502801003945	dimer interface [polypeptide binding]; other site
502801003946	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
502801003947	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
502801003948	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
502801003949	dimer interface [polypeptide binding]; other site
502801003950	active site
502801003951	citrylCoA binding site [chemical binding]; other site
502801003952	NADH binding [chemical binding]; other site
502801003953	cationic pore residues; other site
502801003954	oxalacetate/citrate binding site [chemical binding]; other site
502801003955	coenzyme A binding site [chemical binding]; other site
502801003956	catalytic triad [active]
502801003957	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
502801003958	Iron-sulfur protein interface; other site
502801003959	proximal quinone binding site [chemical binding]; other site
502801003960	SdhD (CybS) interface [polypeptide binding]; other site
502801003961	proximal heme binding site [chemical binding]; other site
502801003962	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
502801003963	SdhC subunit interface [polypeptide binding]; other site
502801003964	proximal heme binding site [chemical binding]; other site
502801003965	cardiolipin binding site; other site
502801003966	Iron-sulfur protein interface; other site
502801003967	proximal quinone binding site [chemical binding]; other site
502801003968	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
502801003969	L-aspartate oxidase; Provisional; Region: PRK06175
502801003970	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
502801003971	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
502801003972	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
502801003973	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
502801003974	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
502801003975	TPP-binding site [chemical binding]; other site
502801003976	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
502801003977	dimer interface [polypeptide binding]; other site
502801003978	PYR/PP interface [polypeptide binding]; other site
502801003979	TPP binding site [chemical binding]; other site
502801003980	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
502801003981	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
502801003982	E3 interaction surface; other site
502801003983	lipoyl attachment site [posttranslational modification]; other site
502801003984	e3 binding domain; Region: E3_binding; pfam02817
502801003985	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
502801003986	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
502801003987	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
502801003988	CoA-ligase; Region: Ligase_CoA; pfam00549
502801003989	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
502801003990	CoA binding domain; Region: CoA_binding; smart00881
502801003991	CoA-ligase; Region: Ligase_CoA; pfam00549
502801003992	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
502801003993	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
502801003994	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
502801003995	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
502801003996	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
502801003997	hypothetical protein; Provisional; Region: PRK10588
502801003998	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
502801003999	active site
502801004000	colicin uptake protein TolQ; Provisional; Region: PRK10801
502801004001	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
502801004002	colicin uptake protein TolR; Provisional; Region: PRK11024
502801004003	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
502801004004	TolA C-terminal; Region: TolA; pfam06519
502801004005	translocation protein TolB; Provisional; Region: tolB; PRK03629
502801004006	TolB amino-terminal domain; Region: TolB_N; pfam04052
502801004007	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
502801004008	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
502801004009	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
502801004010	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
502801004011	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
502801004012	ligand binding site [chemical binding]; other site
502801004013	tol-pal system protein YbgF; Provisional; Region: PRK10803
502801004014	Tetratricopeptide repeat; Region: TPR_6; pfam13174
502801004015	quinolinate synthetase; Provisional; Region: PRK09375
502801004016	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
502801004017	zinc transporter ZitB; Provisional; Region: PRK03557
502801004018	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
502801004019	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
502801004020	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
502801004021	catalytic core [active]
502801004022	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
502801004023	psiF repeat; Region: PsiF_repeat; pfam07769
502801004024	psiF repeat; Region: PsiF_repeat; pfam07769
502801004025	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
502801004026	active site
502801004027	catalytic residues [active]
502801004028	galactokinase; Provisional; Region: PRK05101
502801004029	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
502801004030	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
502801004031	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
502801004032	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
502801004033	dimer interface [polypeptide binding]; other site
502801004034	active site
502801004035	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
502801004036	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
502801004037	NAD binding site [chemical binding]; other site
502801004038	homodimer interface [polypeptide binding]; other site
502801004039	active site
502801004040	substrate binding site [chemical binding]; other site
502801004041	CAAX protease self-immunity; Region: Abi; pfam02517
502801004042	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
502801004043	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801004044	Walker A/P-loop; other site
502801004045	ATP binding site [chemical binding]; other site
502801004046	ABC transporter signature motif; other site
502801004047	Walker B; other site
502801004048	D-loop; other site
502801004049	H-loop/switch region; other site
502801004050	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801004051	Walker A/P-loop; other site
502801004052	ATP binding site [chemical binding]; other site
502801004053	Q-loop/lid; other site
502801004054	ABC transporter signature motif; other site
502801004055	Walker B; other site
502801004056	D-loop; other site
502801004057	H-loop/switch region; other site
502801004058	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
502801004059	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
502801004060	molybdenum-pterin binding domain; Region: Mop; TIGR00638
502801004061	Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585
502801004062	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
502801004063	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
502801004064	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
502801004065	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
502801004066	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004067	dimer interface [polypeptide binding]; other site
502801004068	conserved gate region; other site
502801004069	putative PBP binding loops; other site
502801004070	ABC-ATPase subunit interface; other site
502801004071	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
502801004072	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801004073	Walker A/P-loop; other site
502801004074	ATP binding site [chemical binding]; other site
502801004075	Q-loop/lid; other site
502801004076	ABC transporter signature motif; other site
502801004077	Walker B; other site
502801004078	D-loop; other site
502801004079	H-loop/switch region; other site
502801004080	molybdenum-pterin binding domain; Region: Mop; TIGR00638
502801004081	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
502801004082	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801004083	active site
502801004084	motif I; other site
502801004085	motif II; other site
502801004086	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801004087	6-phosphogluconolactonase; Provisional; Region: PRK11028
502801004088	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
502801004089	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
502801004090	inhibitor-cofactor binding pocket; inhibition site
502801004091	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801004092	catalytic residue [active]
502801004093	biotin synthase; Provisional; Region: PRK15108
502801004094	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801004095	FeS/SAM binding site; other site
502801004096	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
502801004097	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
502801004098	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
502801004099	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801004100	catalytic residue [active]
502801004101	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
502801004102	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801004103	S-adenosylmethionine binding site [chemical binding]; other site
502801004104	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
502801004105	AAA domain; Region: AAA_26; pfam13500
502801004106	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
502801004107	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
502801004108	Walker A/P-loop; other site
502801004109	ATP binding site [chemical binding]; other site
502801004110	Q-loop/lid; other site
502801004111	ABC transporter signature motif; other site
502801004112	Walker B; other site
502801004113	D-loop; other site
502801004114	H-loop/switch region; other site
502801004115	excinuclease ABC subunit B; Provisional; Region: PRK05298
502801004116	Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286
502801004117	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
502801004118	ATP-binding site [chemical binding]; other site
502801004119	ATP binding site [chemical binding]; other site
502801004120	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801004121	nucleotide binding region [chemical binding]; other site
502801004122	ATP-binding site [chemical binding]; other site
502801004123	Ultra-violet resistance protein B; Region: UvrB; pfam12344
502801004124	UvrB/uvrC motif; Region: UVR; pfam02151
502801004125	Uncharacterized conserved protein [Function unknown]; Region: COG4628
502801004126	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
502801004127	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
502801004128	phosphate binding site [ion binding]; other site
502801004129	putative substrate binding pocket [chemical binding]; other site
502801004130	dimer interface [polypeptide binding]; other site
502801004131	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
502801004132	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801004133	FeS/SAM binding site; other site
502801004134	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
502801004135	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
502801004136	trimer interface [polypeptide binding]; other site
502801004137	dimer interface [polypeptide binding]; other site
502801004138	putative active site [active]
502801004139	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
502801004140	MoaE interaction surface [polypeptide binding]; other site
502801004141	MoeB interaction surface [polypeptide binding]; other site
502801004142	thiocarboxylated glycine; other site
502801004143	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
502801004144	MoaE homodimer interface [polypeptide binding]; other site
502801004145	MoaD interaction [polypeptide binding]; other site
502801004146	active site residues [active]
502801004147	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
502801004148	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
502801004149	choline dehydrogenase; Validated; Region: PRK02106
502801004150	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
502801004151	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
502801004152	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
502801004153	NAD(P) binding site [chemical binding]; other site
502801004154	catalytic residues [active]
502801004155	transcriptional regulator BetI; Validated; Region: PRK00767
502801004156	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
502801004157	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
502801004158	choline transport protein BetT; Provisional; Region: PRK09928
502801004159	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
502801004160	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801004161	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
502801004162	putative dimerization interface [polypeptide binding]; other site
502801004163	putative substrate binding pocket [chemical binding]; other site
502801004164	EamA-like transporter family; Region: EamA; pfam00892
502801004165	xanthosine phosphorylase; Region: XAPA; TIGR01699
502801004166	nucleoside transporter; Region: 2A0110; TIGR00889
502801004167	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801004168	putative substrate translocation pore; other site
502801004169	zinc resistance protein; Provisional; Region: zraP; PRK11546
502801004170	dimer interface [polypeptide binding]; other site
502801004171	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
502801004172	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
502801004173	putative active site [active]
502801004174	heme pocket [chemical binding]; other site
502801004175	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801004176	dimer interface [polypeptide binding]; other site
502801004177	phosphorylation site [posttranslational modification]
502801004178	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801004179	ATP binding site [chemical binding]; other site
502801004180	Mg2+ binding site [ion binding]; other site
502801004181	G-X-G motif; other site
502801004182	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
502801004183	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801004184	active site
502801004185	phosphorylation site [posttranslational modification]
502801004186	intermolecular recognition site; other site
502801004187	dimerization interface [polypeptide binding]; other site
502801004188	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801004189	Walker A motif; other site
502801004190	ATP binding site [chemical binding]; other site
502801004191	Walker B motif; other site
502801004192	arginine finger; other site
502801004193	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
502801004194	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
502801004195	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
502801004196	FMN binding site [chemical binding]; other site
502801004197	active site
502801004198	substrate binding site [chemical binding]; other site
502801004199	catalytic residue [active]
502801004200	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801004201	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801004202	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_6; cd08475
502801004203	putative effector binding pocket; other site
502801004204	putative dimerization interface [polypeptide binding]; other site
502801004205	conserved hypothetical protein; Region: TIGR02118
502801004206	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
502801004207	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
502801004208	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
502801004209	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
502801004210	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
502801004211	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
502801004212	Walker A/P-loop; other site
502801004213	ATP binding site [chemical binding]; other site
502801004214	Q-loop/lid; other site
502801004215	ABC transporter signature motif; other site
502801004216	Walker B; other site
502801004217	D-loop; other site
502801004218	H-loop/switch region; other site
502801004219	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
502801004220	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
502801004221	Walker A/P-loop; other site
502801004222	ATP binding site [chemical binding]; other site
502801004223	Q-loop/lid; other site
502801004224	ABC transporter signature motif; other site
502801004225	Walker B; other site
502801004226	D-loop; other site
502801004227	H-loop/switch region; other site
502801004228	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
502801004229	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801004230	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801004231	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
502801004232	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
502801004233	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
502801004234	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
502801004235	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
502801004236	ATP binding site [chemical binding]; other site
502801004237	Mg++ binding site [ion binding]; other site
502801004238	motif III; other site
502801004239	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801004240	nucleotide binding region [chemical binding]; other site
502801004241	ATP-binding site [chemical binding]; other site
502801004242	DDE superfamily endonuclease; Region: DDE_3; pfam13358
502801004243	Transposase; Region: DEDD_Tnp_IS110; pfam01548
502801004244	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
502801004245	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
502801004246	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
502801004247	FMN binding site [chemical binding]; other site
502801004248	active site
502801004249	catalytic residues [active]
502801004250	substrate binding site [chemical binding]; other site
502801004251	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
502801004252	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
502801004253	D-lactate dehydrogenase; Provisional; Region: PRK11183
502801004254	FAD binding domain; Region: FAD_binding_4; pfam01565
502801004255	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
502801004256	Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily; Region: CYTH-like_AC_IV-like; cd07890
502801004257	putative active site [active]
502801004258	putative metal binding residues [ion binding]; other site
502801004259	signature motif; other site
502801004260	putative triphosphate binding site [ion binding]; other site
502801004261	dimer interface [polypeptide binding]; other site
502801004262	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
502801004263	active site
502801004264	Suppressor of fused protein (SUFU); Region: SUFU; pfam05076
502801004265	hypothetical protein; Provisional; Region: PRK10457
502801004266	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
502801004267	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
502801004268	Walker A/P-loop; other site
502801004269	ATP binding site [chemical binding]; other site
502801004270	Q-loop/lid; other site
502801004271	ABC transporter signature motif; other site
502801004272	Walker B; other site
502801004273	D-loop; other site
502801004274	H-loop/switch region; other site
502801004275	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
502801004276	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
502801004277	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
502801004278	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004279	dimer interface [polypeptide binding]; other site
502801004280	conserved gate region; other site
502801004281	putative PBP binding loops; other site
502801004282	ABC-ATPase subunit interface; other site
502801004283	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
502801004284	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004285	dimer interface [polypeptide binding]; other site
502801004286	conserved gate region; other site
502801004287	putative PBP binding loops; other site
502801004288	ABC-ATPase subunit interface; other site
502801004289	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
502801004290	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
502801004291	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
502801004292	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
502801004293	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
502801004294	putative ligand binding site [chemical binding]; other site
502801004295	HEAT repeats; Region: HEAT_2; pfam13646
502801004296	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
502801004297	TM-ABC transporter signature motif; other site
502801004298	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
502801004299	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
502801004300	TM-ABC transporter signature motif; other site
502801004301	Uncharacterized ABC-type transport system, ATPase component [General function prediction only]; Region: COG4674
502801004302	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
502801004303	Walker A/P-loop; other site
502801004304	ATP binding site [chemical binding]; other site
502801004305	Q-loop/lid; other site
502801004306	ABC transporter signature motif; other site
502801004307	Walker B; other site
502801004308	D-loop; other site
502801004309	H-loop/switch region; other site
502801004310	urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410
502801004311	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
502801004312	Walker A/P-loop; other site
502801004313	ATP binding site [chemical binding]; other site
502801004314	Q-loop/lid; other site
502801004315	ABC transporter signature motif; other site
502801004316	Walker B; other site
502801004317	D-loop; other site
502801004318	H-loop/switch region; other site
502801004319	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; cl17304
502801004320	tyrosine decarboxylase; Region: PLN02880
502801004321	Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; Region: GadB; COG0076
502801004322	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801004323	catalytic residue [active]
502801004324	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
502801004325	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
502801004326	active site residue [active]
502801004327	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
502801004328	active site residue [active]
502801004329	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
502801004330	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004331	dimer interface [polypeptide binding]; other site
502801004332	conserved gate region; other site
502801004333	ABC-ATPase subunit interface; other site
502801004334	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
502801004335	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
502801004336	Walker A/P-loop; other site
502801004337	ATP binding site [chemical binding]; other site
502801004338	Q-loop/lid; other site
502801004339	ABC transporter signature motif; other site
502801004340	Walker B; other site
502801004341	D-loop; other site
502801004342	H-loop/switch region; other site
502801004343	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
502801004344	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004345	putative PBP binding loops; other site
502801004346	dimer interface [polypeptide binding]; other site
502801004347	ABC-ATPase subunit interface; other site
502801004348	arginine:agmatin antiporter; Provisional; Region: PRK10644
502801004349	arginine decarboxylase; Provisional; Region: PRK15029
502801004350	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
502801004351	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
502801004352	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801004353	catalytic residue [active]
502801004354	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
502801004355	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
502801004356	EamA-like transporter family; Region: EamA; pfam00892
502801004357	EamA-like transporter family; Region: EamA; pfam00892
502801004358	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
502801004359	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
502801004360	trimer interface [polypeptide binding]; other site
502801004361	eyelet of channel; other site
502801004362	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
502801004363	DEAD_2; Region: DEAD_2; pfam06733
502801004364	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
502801004365	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
502801004366	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
502801004367	tetramer interface [polypeptide binding]; other site
502801004368	heme binding pocket [chemical binding]; other site
502801004369	NADPH binding site [chemical binding]; other site
502801004370	YfaZ precursor; Region: YfaZ; pfam07437
502801004371	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
502801004372	tyrosine transporter TyrP; Provisional; Region: PRK15132
502801004373	aromatic amino acid transport protein; Region: araaP; TIGR00837
502801004374	hypothetical protein; Provisional; Region: PRK03673
502801004375	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
502801004376	putative MPT binding site; other site
502801004377	Competence-damaged protein; Region: CinA; cl00666
502801004378	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
502801004379	secondary substrate binding site; other site
502801004380	primary substrate binding site; other site
502801004381	inhibition loop; other site
502801004382	dimerization interface [polypeptide binding]; other site
502801004383	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
502801004384	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
502801004385	catalytic loop [active]
502801004386	iron binding site [ion binding]; other site
502801004387	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
502801004388	dimer interface [polypeptide binding]; other site
502801004389	putative radical transfer pathway; other site
502801004390	diiron center [ion binding]; other site
502801004391	tyrosyl radical; other site
502801004392	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
502801004393	ATP cone domain; Region: ATP-cone; pfam03477
502801004394	Class I ribonucleotide reductase; Region: RNR_I; cd01679
502801004395	active site
502801004396	dimer interface [polypeptide binding]; other site
502801004397	catalytic residues [active]
502801004398	effector binding site; other site
502801004399	R2 peptide binding site; other site
502801004400	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
502801004401	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801004402	S-adenosylmethionine binding site [chemical binding]; other site
502801004403	DNA gyrase subunit A; Validated; Region: PRK05560
502801004404	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
502801004405	CAP-like domain; other site
502801004406	active site
502801004407	primary dimer interface [polypeptide binding]; other site
502801004408	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
502801004409	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
502801004410	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
502801004411	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
502801004412	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
502801004413	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
502801004414	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
502801004415	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801004416	dimer interface [polypeptide binding]; other site
502801004417	phosphorylation site [posttranslational modification]
502801004418	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801004419	ATP binding site [chemical binding]; other site
502801004420	Mg2+ binding site [ion binding]; other site
502801004421	G-X-G motif; other site
502801004422	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
502801004423	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801004424	active site
502801004425	phosphorylation site [posttranslational modification]
502801004426	intermolecular recognition site; other site
502801004427	dimerization interface [polypeptide binding]; other site
502801004428	transcriptional regulator RcsB; Provisional; Region: PRK10840
502801004429	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801004430	active site
502801004431	phosphorylation site [posttranslational modification]
502801004432	intermolecular recognition site; other site
502801004433	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801004434	DNA binding residues [nucleotide binding]
502801004435	dimerization interface [polypeptide binding]; other site
502801004436	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
502801004437	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801004438	ATP binding site [chemical binding]; other site
502801004439	Mg2+ binding site [ion binding]; other site
502801004440	G-X-G motif; other site
502801004441	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
502801004442	putative binding surface; other site
502801004443	active site
502801004444	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
502801004445	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
502801004446	trimer interface [polypeptide binding]; other site
502801004447	eyelet of channel; other site
502801004448	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
502801004449	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
502801004450	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
502801004451	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
502801004452	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
502801004453	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
502801004454	Cache domain; Region: Cache_1; pfam02743
502801004455	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801004456	dimerization interface [polypeptide binding]; other site
502801004457	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
502801004458	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
502801004459	dimer interface [polypeptide binding]; other site
502801004460	putative CheW interface [polypeptide binding]; other site
502801004461	Outer membrane protease [Cell envelope biogenesis, outer membrane]; Region: OmpT; COG4571
502801004462	DinI-like family; Region: DinI; cl11630
502801004463	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
502801004464	non-specific DNA binding site [nucleotide binding]; other site
502801004465	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
502801004466	salt bridge; other site
502801004467	sequence-specific DNA binding site [nucleotide binding]; other site
502801004468	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
502801004469	Catalytic site [active]
502801004470	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
502801004471	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
502801004472	putative aldolase; Validated; Region: PRK08130
502801004473	intersubunit interface [polypeptide binding]; other site
502801004474	active site
502801004475	Zn2+ binding site [ion binding]; other site
502801004476	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
502801004477	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
502801004478	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
502801004479	Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622
502801004480	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
502801004481	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
502801004482	Protein of unknown function (DUF2635); Region: DUF2635; pfam10948
502801004483	Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386
502801004484	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
502801004485	Phage tail tube protein; Region: Tail_tube; pfam10618
502801004486	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
502801004487	Mu-like prophage DNA circulation protein [General function prediction only]; Region: COG4228
502801004488	DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157
502801004489	Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379
502801004490	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
502801004491	Mu-like prophage protein gp45 [Function unknown]; Region: COG4384
502801004492	Mu-like prophage protein gp46 [Function unknown]; Region: COG4381
502801004493	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
502801004494	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3778
502801004495	Phage Tail Collar Domain; Region: Collar; pfam07484
502801004496	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
502801004497	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
502801004498	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
502801004499	putative active site [active]
502801004500	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
502801004501	beta-galactosidase; Region: BGL; TIGR03356
502801004502	Bacterial self-protective colicin-like immunity; Region: Colicin_immun; pfam09204
502801004503	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
502801004504	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
502801004505	Sulfatase; Region: Sulfatase; cl17466
502801004506	hypothetical protein; Provisional; Region: PRK13689
502801004507	Nucleoid-associated protein [General function prediction only]; Region: COG3081
502801004508	nucleoid-associated protein NdpA; Validated; Region: PRK00378
502801004509	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
502801004510	5S rRNA interface [nucleotide binding]; other site
502801004511	CTC domain interface [polypeptide binding]; other site
502801004512	L16 interface [polypeptide binding]; other site
502801004513	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
502801004514	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
502801004515	ATP binding site [chemical binding]; other site
502801004516	putative Mg++ binding site [ion binding]; other site
502801004517	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801004518	nucleotide binding region [chemical binding]; other site
502801004519	ATP-binding site [chemical binding]; other site
502801004520	Double zinc ribbon; Region: DZR; pfam12773
502801004521	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
502801004522	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
502801004523	RNA binding surface [nucleotide binding]; other site
502801004524	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
502801004525	active site
502801004526	uracil binding [chemical binding]; other site
502801004527	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801004528	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
502801004529	putative substrate translocation pore; other site
502801004530	hypothetical protein; Provisional; Region: PRK11835
502801004531	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
502801004532	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801004533	Walker A/P-loop; other site
502801004534	ATP binding site [chemical binding]; other site
502801004535	Q-loop/lid; other site
502801004536	ABC transporter signature motif; other site
502801004537	Walker B; other site
502801004538	D-loop; other site
502801004539	H-loop/switch region; other site
502801004540	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
502801004541	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801004542	Walker A/P-loop; other site
502801004543	ATP binding site [chemical binding]; other site
502801004544	Q-loop/lid; other site
502801004545	ABC transporter signature motif; other site
502801004546	Walker B; other site
502801004547	D-loop; other site
502801004548	H-loop/switch region; other site
502801004549	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239
502801004550	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
502801004551	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004552	dimer interface [polypeptide binding]; other site
502801004553	conserved gate region; other site
502801004554	putative PBP binding loops; other site
502801004555	ABC-ATPase subunit interface; other site
502801004556	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
502801004557	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004558	dimer interface [polypeptide binding]; other site
502801004559	conserved gate region; other site
502801004560	putative PBP binding loops; other site
502801004561	ABC-ATPase subunit interface; other site
502801004562	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
502801004563	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
502801004564	phage resistance protein; Provisional; Region: PRK10551
502801004565	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
502801004566	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
502801004567	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
502801004568	NlpC/P60 family; Region: NLPC_P60; pfam00877
502801004569	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
502801004570	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
502801004571	active site
502801004572	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
502801004573	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
502801004574	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
502801004575	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
502801004576	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801004577	DNA-binding site [nucleotide binding]; DNA binding site
502801004578	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
502801004579	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
502801004580	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
502801004581	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
502801004582	mannonate dehydratase; Provisional; Region: PRK03906
502801004583	mannonate dehydratase; Region: uxuA; TIGR00695
502801004584	elongation factor P; Provisional; Region: PRK04542
502801004585	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
502801004586	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
502801004587	RNA binding site [nucleotide binding]; other site
502801004588	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
502801004589	RNA binding site [nucleotide binding]; other site
502801004590	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
502801004591	aromatic amino acid transport protein; Region: araaP; TIGR00837
502801004592	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
502801004593	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
502801004594	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801004595	NAD(P) binding site [chemical binding]; other site
502801004596	active site
502801004597	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
502801004598	C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor; Region: CtBP_dh; cd05299
502801004599	ligand binding site [chemical binding]; other site
502801004600	NAD binding site [chemical binding]; other site
502801004601	catalytic site [active]
502801004602	Fumarylacetoacetate (FAA) hydrolase family protein [General function prediction only]; Region: COG3970
502801004603	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
502801004604	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
502801004605	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
502801004606	tetramerization interface [polypeptide binding]; other site
502801004607	NAD(P) binding site [chemical binding]; other site
502801004608	catalytic residues [active]
502801004609	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
502801004610	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
502801004611	N- and C-terminal domain interface [polypeptide binding]; other site
502801004612	active site
502801004613	MgATP binding site [chemical binding]; other site
502801004614	catalytic site [active]
502801004615	metal binding site [ion binding]; metal-binding site
502801004616	xylulose binding site [chemical binding]; other site
502801004617	homodimer interface [polypeptide binding]; other site
502801004618	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
502801004619	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
502801004620	ligand binding site [chemical binding]; other site
502801004621	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801004622	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801004623	Walker A/P-loop; other site
502801004624	ATP binding site [chemical binding]; other site
502801004625	Q-loop/lid; other site
502801004626	ABC transporter signature motif; other site
502801004627	Walker B; other site
502801004628	D-loop; other site
502801004629	H-loop/switch region; other site
502801004630	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801004631	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801004632	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801004633	TM-ABC transporter signature motif; other site
502801004634	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_19; cd04678
502801004635	nudix motif; other site
502801004636	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
502801004637	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
502801004638	active site
502801004639	phosphorylation site [posttranslational modification]
502801004640	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
502801004641	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
502801004642	dimerization domain swap beta strand [polypeptide binding]; other site
502801004643	regulatory protein interface [polypeptide binding]; other site
502801004644	active site
502801004645	regulatory phosphorylation site [posttranslational modification]; other site
502801004646	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
502801004647	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
502801004648	putative substrate binding site [chemical binding]; other site
502801004649	putative ATP binding site [chemical binding]; other site
502801004650	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
502801004651	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
502801004652	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
502801004653	active site
502801004654	P-loop; other site
502801004655	phosphorylation site [posttranslational modification]
502801004656	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
502801004657	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
502801004658	DNA binding site [nucleotide binding]
502801004659	pili assembly chaperone protein SafB; Provisional; Region: PRK15224
502801004660	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801004661	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
502801004662	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
502801004663	PapC N-terminal domain; Region: PapC_N; pfam13954
502801004664	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
502801004665	PapC C-terminal domain; Region: PapC_C; pfam13953
502801004666	endonuclease IV; Provisional; Region: PRK01060
502801004667	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
502801004668	AP (apurinic/apyrimidinic) site pocket; other site
502801004669	DNA interaction; other site
502801004670	Metal-binding active site; metal-binding site
502801004671	Predicted membrane protein [Function unknown]; Region: COG2855
502801004672	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
502801004673	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801004674	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
502801004675	putative dimerization interface [polypeptide binding]; other site
502801004676	lysine transporter; Provisional; Region: PRK10836
502801004677	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
502801004678	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
502801004679	putative ligand binding residues [chemical binding]; other site
502801004680	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
502801004681	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
502801004682	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801004683	ABC-ATPase subunit  interface; other site
502801004684	dimer interface [polypeptide binding]; other site
502801004685	putative PBP binding regions; other site
502801004686	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
502801004687	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
502801004688	Walker A/P-loop; other site
502801004689	ATP binding site [chemical binding]; other site
502801004690	Q-loop/lid; other site
502801004691	ABC transporter signature motif; other site
502801004692	Walker B; other site
502801004693	D-loop; other site
502801004694	H-loop/switch region; other site
502801004695	putative outer membrane receptor; Provisional; Region: PRK13513
502801004696	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801004697	N-terminal plug; other site
502801004698	ligand-binding site [chemical binding]; other site
502801004699	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
502801004700	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
502801004701	putative C-terminal domain interface [polypeptide binding]; other site
502801004702	putative GSH binding site (G-site) [chemical binding]; other site
502801004703	putative dimer interface [polypeptide binding]; other site
502801004704	C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180
502801004705	putative N-terminal domain interface [polypeptide binding]; other site
502801004706	putative dimer interface [polypeptide binding]; other site
502801004707	putative substrate binding pocket (H-site) [chemical binding]; other site
502801004708	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
502801004709	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
502801004710	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
502801004711	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
502801004712	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
502801004713	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
502801004714	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
502801004715	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
502801004716	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
502801004717	Walker A/P-loop; other site
502801004718	ATP binding site [chemical binding]; other site
502801004719	Q-loop/lid; other site
502801004720	ABC transporter signature motif; other site
502801004721	Walker B; other site
502801004722	D-loop; other site
502801004723	H-loop/switch region; other site
502801004724	NIL domain; Region: NIL; pfam09383
502801004725	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004726	dimer interface [polypeptide binding]; other site
502801004727	conserved gate region; other site
502801004728	ABC-ATPase subunit interface; other site
502801004729	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
502801004730	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
502801004731	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
502801004732	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
502801004733	serine transporter; Region: stp; TIGR00814
502801004734	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
502801004735	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
502801004736	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
502801004737	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
502801004738	intersubunit interface [polypeptide binding]; other site
502801004739	active site
502801004740	catalytic residue [active]
502801004741	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
502801004742	active site
502801004743	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
502801004744	PAP2_like_6 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which mainly contains bacterial proteins, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_6; cd03396
502801004745	active site
502801004746	putative transporter; Provisional; Region: PRK04972
502801004747	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
502801004748	TrkA-C domain; Region: TrkA_C; pfam02080
502801004749	TrkA-C domain; Region: TrkA_C; pfam02080
502801004750	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
502801004751	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
502801004752	GSH binding site [chemical binding]; other site
502801004753	catalytic residues [active]
502801004754	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
502801004755	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
502801004756	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
502801004757	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
502801004758	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
502801004759	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801004760	Walker A/P-loop; other site
502801004761	ATP binding site [chemical binding]; other site
502801004762	Q-loop/lid; other site
502801004763	ABC transporter signature motif; other site
502801004764	Walker B; other site
502801004765	D-loop; other site
502801004766	H-loop/switch region; other site
502801004767	TOBE domain; Region: TOBE_2; pfam08402
502801004768	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004769	dimer interface [polypeptide binding]; other site
502801004770	conserved gate region; other site
502801004771	putative PBP binding loops; other site
502801004772	ABC-ATPase subunit interface; other site
502801004773	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
502801004774	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004775	dimer interface [polypeptide binding]; other site
502801004776	conserved gate region; other site
502801004777	putative PBP binding loops; other site
502801004778	ABC-ATPase subunit interface; other site
502801004779	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
502801004780	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
502801004781	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801004782	S-adenosylmethionine binding site [chemical binding]; other site
502801004783	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
502801004784	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801004785	substrate binding pocket [chemical binding]; other site
502801004786	membrane-bound complex binding site; other site
502801004787	hinge residues; other site
502801004788	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
502801004789	SPFH domain / Band 7 family; Region: Band_7; pfam01145
502801004790	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
502801004791	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
502801004792	putative ligand binding residues [chemical binding]; other site
502801004793	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
502801004794	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801004795	ABC-ATPase subunit  interface; other site
502801004796	dimer interface [polypeptide binding]; other site
502801004797	putative PBP binding regions; other site
502801004798	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
502801004799	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
502801004800	Walker A/P-loop; other site
502801004801	ATP binding site [chemical binding]; other site
502801004802	Q-loop/lid; other site
502801004803	ABC transporter signature motif; other site
502801004804	Walker B; other site
502801004805	D-loop; other site
502801004806	H-loop/switch region; other site
502801004807	Nicotianamine synthase protein; Region: NAS; cl17658
502801004808	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4408
502801004809	Uncharacterized protein conserved in bacteria (DUF2338); Region: DUF2338; pfam10100
502801004810	EamA-like transporter family; Region: EamA; pfam00892
502801004811	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
502801004812	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004813	dimer interface [polypeptide binding]; other site
502801004814	conserved gate region; other site
502801004815	putative PBP binding loops; other site
502801004816	ABC-ATPase subunit interface; other site
502801004817	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
502801004818	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801004819	dimer interface [polypeptide binding]; other site
502801004820	conserved gate region; other site
502801004821	putative PBP binding loops; other site
502801004822	ABC-ATPase subunit interface; other site
502801004823	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
502801004824	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801004825	substrate binding pocket [chemical binding]; other site
502801004826	membrane-bound complex binding site; other site
502801004827	hinge residues; other site
502801004828	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
502801004829	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801004830	Walker A/P-loop; other site
502801004831	ATP binding site [chemical binding]; other site
502801004832	Q-loop/lid; other site
502801004833	ABC transporter signature motif; other site
502801004834	Walker B; other site
502801004835	D-loop; other site
502801004836	H-loop/switch region; other site
502801004837	chorismate mutase; Provisional; Region: PRK08055
502801004838	putative lipoprotein; Provisional; Region: PRK10533
502801004839	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
502801004840	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801004841	NAD(P) binding site [chemical binding]; other site
502801004842	active site
502801004843	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
502801004844	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
502801004845	putative NAD(P) binding site [chemical binding]; other site
502801004846	putative active site [active]
502801004847	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
502801004848	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
502801004849	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
502801004850	tetramer interface [polypeptide binding]; other site
502801004851	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801004852	catalytic residue [active]
502801004853	pyruvate dehydrogenase; Provisional; Region: PRK09124
502801004854	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
502801004855	PYR/PP interface [polypeptide binding]; other site
502801004856	dimer interface [polypeptide binding]; other site
502801004857	tetramer interface [polypeptide binding]; other site
502801004858	TPP binding site [chemical binding]; other site
502801004859	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
502801004860	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
502801004861	TPP-binding site [chemical binding]; other site
502801004862	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
502801004863	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
502801004864	FAD binding pocket [chemical binding]; other site
502801004865	FAD binding motif [chemical binding]; other site
502801004866	phosphate binding motif [ion binding]; other site
502801004867	beta-alpha-beta structure motif; other site
502801004868	NAD binding pocket [chemical binding]; other site
502801004869	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
502801004870	catalytic loop [active]
502801004871	iron binding site [ion binding]; other site
502801004872	hybrid cluster protein; Provisional; Region: PRK05290
502801004873	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
502801004874	ACS interaction site; other site
502801004875	CODH interaction site; other site
502801004876	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
502801004877	hybrid metal cluster; other site
502801004878	Predicted membrane protein [Function unknown]; Region: COG2431
502801004879	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
502801004880	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
502801004881	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
502801004882	putative active site [active]
502801004883	putative metal-binding site [ion binding]; other site
502801004884	Protein of unknown function (DUF535); Region: DUF535; pfam04393
502801004885	macrolide transporter subunit MacA; Provisional; Region: PRK11578
502801004886	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801004887	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801004888	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
502801004889	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
502801004890	Walker A/P-loop; other site
502801004891	ATP binding site [chemical binding]; other site
502801004892	Q-loop/lid; other site
502801004893	ABC transporter signature motif; other site
502801004894	Walker B; other site
502801004895	D-loop; other site
502801004896	H-loop/switch region; other site
502801004897	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
502801004898	FtsX-like permease family; Region: FtsX; pfam02687
502801004899	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
502801004900	DNA-binding site [nucleotide binding]; DNA binding site
502801004901	RNA-binding motif; other site
502801004902	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
502801004903	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
502801004904	Clp amino terminal domain; Region: Clp_N; pfam02861
502801004905	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801004906	Walker A motif; other site
502801004907	ATP binding site [chemical binding]; other site
502801004908	Walker B motif; other site
502801004909	arginine finger; other site
502801004910	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801004911	Walker A motif; other site
502801004912	ATP binding site [chemical binding]; other site
502801004913	Walker B motif; other site
502801004914	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
502801004915	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
502801004916	rRNA binding site [nucleotide binding]; other site
502801004917	predicted 30S ribosome binding site; other site
502801004918	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
502801004919	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
502801004920	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
502801004921	Walker A/P-loop; other site
502801004922	ATP binding site [chemical binding]; other site
502801004923	Q-loop/lid; other site
502801004924	ABC transporter signature motif; other site
502801004925	Walker B; other site
502801004926	D-loop; other site
502801004927	H-loop/switch region; other site
502801004928	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
502801004929	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801004930	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801004931	Walker A/P-loop; other site
502801004932	ATP binding site [chemical binding]; other site
502801004933	Q-loop/lid; other site
502801004934	ABC transporter signature motif; other site
502801004935	Walker B; other site
502801004936	D-loop; other site
502801004937	H-loop/switch region; other site
502801004938	thioredoxin reductase; Provisional; Region: PRK10262
502801004939	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
502801004940	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
502801004941	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
502801004942	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
502801004943	putative DNA binding site [nucleotide binding]; other site
502801004944	putative Zn2+ binding site [ion binding]; other site
502801004945	AsnC family; Region: AsnC_trans_reg; pfam01037
502801004946	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
502801004947	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
502801004948	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
502801004949	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
502801004950	Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl17548
502801004951	recombination factor protein RarA; Reviewed; Region: PRK13342
502801004952	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801004953	Walker A motif; other site
502801004954	ATP binding site [chemical binding]; other site
502801004955	Walker B motif; other site
502801004956	arginine finger; other site
502801004957	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
502801004958	seryl-tRNA synthetase; Provisional; Region: PRK05431
502801004959	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
502801004960	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
502801004961	dimer interface [polypeptide binding]; other site
502801004962	active site
502801004963	motif 1; other site
502801004964	motif 2; other site
502801004965	motif 3; other site
502801004966	putative MFS family transporter protein; Provisional; Region: PRK03633
502801004967	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801004968	putative substrate translocation pore; other site
502801004969	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
502801004970	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801004971	FeS/SAM binding site; other site
502801004972	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
502801004973	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
502801004974	Pyruvate formate lyase 1; Region: PFL1; cd01678
502801004975	coenzyme A binding site [chemical binding]; other site
502801004976	active site
502801004977	catalytic residues [active]
502801004978	glycine loop; other site
502801004979	formate transporter; Provisional; Region: PRK10805
502801004980	uncharacterized domain; Region: TIGR00702
502801004981	YcaO-like family; Region: YcaO; pfam02624
502801004982	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
502801004983	active site
502801004984	homodimer interface [polypeptide binding]; other site
502801004985	homotetramer interface [polypeptide binding]; other site
502801004986	Haemagglutinin; Region: HIM; pfam05662
502801004987	YadA-like C-terminal region; Region: YadA; pfam03895
502801004988	YadA-like C-terminal region; Region: YadA; pfam03895
502801004989	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
502801004990	homodimer interface [polypeptide binding]; other site
502801004991	substrate-cofactor binding pocket; other site
502801004992	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801004993	catalytic residue [active]
502801004994	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
502801004995	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
502801004996	hinge; other site
502801004997	active site
502801004998	cytidylate kinase; Provisional; Region: cmk; PRK00023
502801004999	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
502801005000	CMP-binding site; other site
502801005001	The sites determining sugar specificity; other site
502801005002	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
502801005003	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
502801005004	RNA binding site [nucleotide binding]; other site
502801005005	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
502801005006	RNA binding site [nucleotide binding]; other site
502801005007	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
502801005008	RNA binding site [nucleotide binding]; other site
502801005009	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
502801005010	RNA binding site [nucleotide binding]; other site
502801005011	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
502801005012	RNA binding site [nucleotide binding]; other site
502801005013	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
502801005014	RNA binding site [nucleotide binding]; other site
502801005015	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
502801005016	IHF dimer interface [polypeptide binding]; other site
502801005017	IHF - DNA interface [nucleotide binding]; other site
502801005018	ComEC family competence protein; Provisional; Region: PRK11539
502801005019	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
502801005020	Competence protein; Region: Competence; pfam03772
502801005021	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
502801005022	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
502801005023	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801005024	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
502801005025	Walker A/P-loop; other site
502801005026	ATP binding site [chemical binding]; other site
502801005027	Q-loop/lid; other site
502801005028	ABC transporter signature motif; other site
502801005029	Walker B; other site
502801005030	D-loop; other site
502801005031	H-loop/switch region; other site
502801005032	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
502801005033	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
502801005034	Domain of unknown function (DUF1338); Region: DUF1338; pfam07063
502801005035	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
502801005036	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
502801005037	DNA-binding site [nucleotide binding]; DNA binding site
502801005038	RNA-binding motif; other site
502801005039	Trm112p-like protein; Region: Trm112p; cl01066
502801005040	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
502801005041	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
502801005042	Ligand binding site; other site
502801005043	oligomer interface; other site
502801005044	hypothetical protein; Provisional; Region: PRK10593
502801005045	Methyltransferase domain; Region: Methyltransf_31; pfam13847
502801005046	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801005047	S-adenosylmethionine binding site [chemical binding]; other site
502801005048	condesin subunit F; Provisional; Region: PRK05260
502801005049	condesin subunit E; Provisional; Region: PRK05256
502801005050	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
502801005051	P-loop containing region of AAA domain; Region: AAA_29; cl17516
502801005052	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
502801005053	murein L,D-transpeptidase; Provisional; Region: PRK10594
502801005054	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
502801005055	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
502801005056	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
502801005057	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
502801005058	Peptidase M15; Region: Peptidase_M15_3; cl01194
502801005059	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
502801005060	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
502801005061	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801005062	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801005063	homodimer interface [polypeptide binding]; other site
502801005064	catalytic residue [active]
502801005065	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
502801005066	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
502801005067	trimer interface [polypeptide binding]; other site
502801005068	eyelet of channel; other site
502801005069	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
502801005070	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
502801005071	putative dimer interface [polypeptide binding]; other site
502801005072	putative anticodon binding site; other site
502801005073	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
502801005074	homodimer interface [polypeptide binding]; other site
502801005075	motif 1; other site
502801005076	motif 2; other site
502801005077	active site
502801005078	motif 3; other site
502801005079	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
502801005080	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
502801005081	active site
502801005082	aminopeptidase N; Provisional; Region: pepN; PRK14015
502801005083	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
502801005084	active site
502801005085	Zn binding site [ion binding]; other site
502801005086	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
502801005087	MULE transposase domain; Region: MULE; pfam10551
502801005088	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
502801005089	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
502801005090	quinone interaction residues [chemical binding]; other site
502801005091	active site
502801005092	catalytic residues [active]
502801005093	FMN binding site [chemical binding]; other site
502801005094	substrate binding site [chemical binding]; other site
502801005095	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
502801005096	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
502801005097	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
502801005098	MOSC domain; Region: MOSC; pfam03473
502801005099	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
502801005100	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
502801005101	catalytic loop [active]
502801005102	iron binding site [ion binding]; other site
502801005103	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
502801005104	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
502801005105	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801005106	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801005107	S-adenosylmethionine binding site [chemical binding]; other site
502801005108	ABC transporter ATPase component; Reviewed; Region: PRK11147
502801005109	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801005110	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801005111	Walker A/P-loop; other site
502801005112	Walker A/P-loop; other site
502801005113	ATP binding site [chemical binding]; other site
502801005114	ATP binding site [chemical binding]; other site
502801005115	Q-loop/lid; other site
502801005116	Q-loop/lid; other site
502801005117	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
502801005118	ABC transporter signature motif; other site
502801005119	Walker B; other site
502801005120	D-loop; other site
502801005121	ABC transporter; Region: ABC_tran_2; pfam12848
502801005122	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
502801005123	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
502801005124	Paraquat-inducible protein A; Region: PqiA; pfam04403
502801005125	Paraquat-inducible protein A; Region: PqiA; pfam04403
502801005126	paraquat-inducible protein B; Provisional; Region: PRK10807
502801005127	mce related protein; Region: MCE; pfam02470
502801005128	mce related protein; Region: MCE; pfam02470
502801005129	mce related protein; Region: MCE; pfam02470
502801005130	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
502801005131	Protein of unknown function (DUF330); Region: DUF330; pfam03886
502801005132	Ribosome modulation factor; Region: RMF; pfam04957
502801005133	Transposase IS200 like; Region: Y1_Tnp; pfam01797
502801005134	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK06333
502801005135	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
502801005136	dimer interface [polypeptide binding]; other site
502801005137	active site
502801005138	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
502801005139	active site 2 [active]
502801005140	dimer interface [polypeptide binding]; other site
502801005141	active site 1 [active]
502801005142	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
502801005143	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
502801005144	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
502801005145	outer membrane protein A; Reviewed; Region: PRK10808
502801005146	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
502801005147	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
502801005148	ligand binding site [chemical binding]; other site
502801005149	SOS-response cell division inhibitor, blocks FtsZ ring formation [Cell division and chromosome partitioning]; Region: SulA; COG5404
502801005150	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
502801005151	TfoX C-terminal domain; Region: TfoX_C; pfam04994
502801005152	TIGR01666 family membrane protein; Region: YCCS
502801005153	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
502801005154	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
502801005155	Predicted membrane protein [Function unknown]; Region: COG3304
502801005156	Domain of unknown function (DUF307); Region: DUF307; pfam03733
502801005157	DNA helicase IV; Provisional; Region: helD; PRK11054
502801005158	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
502801005159	Part of AAA domain; Region: AAA_19; pfam13245
502801005160	Family description; Region: UvrD_C_2; pfam13538
502801005161	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
502801005162	active site
502801005163	dimer interfaces [polypeptide binding]; other site
502801005164	catalytic residues [active]
502801005165	hypothetical protein; Provisional; Region: PRK03641
502801005166	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
502801005167	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
502801005168	heat shock protein HspQ; Provisional; Region: PRK14129
502801005169	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
502801005170	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
502801005171	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
502801005172	putative RNA binding site [nucleotide binding]; other site
502801005173	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801005174	S-adenosylmethionine binding site [chemical binding]; other site
502801005175	acylphosphatase; Provisional; Region: PRK14426
502801005176	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
502801005177	sulfur relay protein, TusE/DsrC/DsvC family; Region: dsrC_tusE_dsvC; TIGR03342
502801005178	Integrase core domain; Region: rve; pfam00665
502801005179	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
502801005180	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
502801005181	FAD binding domain; Region: FAD_binding_4; pfam01565
502801005182	short chain dehydrogenase; Provisional; Region: PRK06172
502801005183	classical (c) SDRs; Region: SDR_c; cd05233
502801005184	NAD(P) binding site [chemical binding]; other site
502801005185	active site
502801005186	FabA/Z, beta-hydroxyacyl-acyl carrier protein (ACP)-dehydratases: One of several distinct enzyme types of the dissociative, type II, fatty acid synthase system (found in bacteria and plants) required to complete successive cycles of fatty acid elongation; Region: FabA_FabZ; cd00493
502801005187	active site 2 [active]
502801005188	dimer interface [polypeptide binding]; other site
502801005189	active site 1 [active]
502801005190	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
502801005191	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
502801005192	dimer interface [polypeptide binding]; other site
502801005193	active site
502801005194	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
502801005195	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801005196	NAD(P) binding site [chemical binding]; other site
502801005197	active site
502801005198	3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism]; Region: PksG; COG3425
502801005199	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
502801005200	dimer interface [polypeptide binding]; other site
502801005201	active site
502801005202	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
502801005203	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
502801005204	substrate binding site [chemical binding]; other site
502801005205	oxyanion hole (OAH) forming residues; other site
502801005206	trimer interface [polypeptide binding]; other site
502801005207	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
502801005208	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
502801005209	substrate binding site [chemical binding]; other site
502801005210	oxyanion hole (OAH) forming residues; other site
502801005211	trimer interface [polypeptide binding]; other site
502801005212	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
502801005213	classical (c) SDRs; Region: SDR_c; cd05233
502801005214	NAD(P) binding site [chemical binding]; other site
502801005215	active site
502801005216	Lipocalin-like domain; Region: Lipocalin_5; pfam13924
502801005217	acyl carrier protein; Validated; Region: PRK07117
502801005218	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
502801005219	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
502801005220	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
502801005221	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
502801005222	Protein of unknown function (DUF877); Region: DUF877; pfam05943
502801005223	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
502801005224	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
502801005225	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
502801005226	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
502801005227	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
502801005228	ligand binding site [chemical binding]; other site
502801005229	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
502801005230	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
502801005231	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801005232	Walker A motif; other site
502801005233	ATP binding site [chemical binding]; other site
502801005234	Walker B motif; other site
502801005235	arginine finger; other site
502801005236	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801005237	Walker A motif; other site
502801005238	ATP binding site [chemical binding]; other site
502801005239	Walker B motif; other site
502801005240	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
502801005241	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
502801005242	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
502801005243	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
502801005244	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
502801005245	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
502801005246	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
502801005247	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
502801005248	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
502801005249	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
502801005250	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
502801005251	virion protein; Provisional; Region: V; PHA02564
502801005252	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
502801005253	TIGR02594 family protein; Region: TIGR02594
502801005254	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
502801005255	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
502801005256	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
502801005257	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
502801005258	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
502801005259	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
502801005260	PAAR motif; Region: PAAR_motif; pfam05488
502801005261	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
502801005262	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
502801005263	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
502801005264	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
502801005265	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
502801005266	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
502801005267	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
502801005268	ImpA domain protein; Region: DUF3702; pfam12486
502801005269	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
502801005270	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
502801005271	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801005272	Walker A/P-loop; other site
502801005273	ATP binding site [chemical binding]; other site
502801005274	Q-loop/lid; other site
502801005275	ABC transporter signature motif; other site
502801005276	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
502801005277	Walker B; other site
502801005278	D-loop; other site
502801005279	H-loop/switch region; other site
502801005280	ABC transporter; Region: ABC_tran_2; pfam12848
502801005281	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
502801005282	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
502801005283	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
502801005284	ATP binding site [chemical binding]; other site
502801005285	substrate interface [chemical binding]; other site
502801005286	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
502801005287	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
502801005288	dimer interface [polypeptide binding]; other site
502801005289	putative functional site; other site
502801005290	putative MPT binding site; other site
502801005291	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801005292	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
502801005293	FeS/SAM binding site; other site
502801005294	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
502801005295	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
502801005296	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
502801005297	Walker A/P-loop; other site
502801005298	ATP binding site [chemical binding]; other site
502801005299	Q-loop/lid; other site
502801005300	ABC transporter signature motif; other site
502801005301	Walker B; other site
502801005302	D-loop; other site
502801005303	H-loop/switch region; other site
502801005304	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
502801005305	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801005306	FtsX-like permease family; Region: FtsX; pfam02687
502801005307	S-formylglutathione hydrolase; Region: PLN02442
502801005308	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
502801005309	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
502801005310	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
502801005311	substrate binding site [chemical binding]; other site
502801005312	catalytic Zn binding site [ion binding]; other site
502801005313	NAD binding site [chemical binding]; other site
502801005314	structural Zn binding site [ion binding]; other site
502801005315	dimer interface [polypeptide binding]; other site
502801005316	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801005317	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801005318	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
502801005319	putative dimerization interface [polypeptide binding]; other site
502801005320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801005321	putative substrate translocation pore; other site
502801005322	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
502801005323	GTP cyclohydrolase I; Provisional; Region: PLN03044
502801005324	active site
502801005325	Predicted membrane protein [Function unknown]; Region: COG2311
502801005326	hypothetical protein; Provisional; Region: PRK10835
502801005327	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
502801005328	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
502801005329	ligand binding site [chemical binding]; other site
502801005330	calcium binding site [ion binding]; other site
502801005331	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801005332	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
502801005333	Walker A/P-loop; other site
502801005334	ATP binding site [chemical binding]; other site
502801005335	Q-loop/lid; other site
502801005336	ABC transporter signature motif; other site
502801005337	Walker B; other site
502801005338	D-loop; other site
502801005339	H-loop/switch region; other site
502801005340	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801005341	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801005342	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801005343	TM-ABC transporter signature motif; other site
502801005344	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
502801005345	putative active site [active]
502801005346	malate dehydrogenase; Provisional; Region: PRK13529
502801005347	Malic enzyme, N-terminal domain; Region: malic; pfam00390
502801005348	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
502801005349	NAD(P) binding site [chemical binding]; other site
502801005350	cytidine deaminase; Provisional; Region: PRK09027
502801005351	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
502801005352	active site
502801005353	catalytic motif [active]
502801005354	Zn binding site [ion binding]; other site
502801005355	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
502801005356	active site
502801005357	catalytic motif [active]
502801005358	Zn binding site [ion binding]; other site
502801005359	hypothetical protein; Provisional; Region: PRK10711
502801005360	hypothetical protein; Provisional; Region: PRK01821
502801005361	putative transporter; Provisional; Region: PRK10054
502801005362	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801005363	putative substrate translocation pore; other site
502801005364	Uncharacterized conserved protein [Function unknown]; Region: COG5276
502801005365	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
502801005366	Methylthioribose-binding protein-like of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_methylthioribose_binding_like; cd06305
502801005367	putative ligand binding site [chemical binding]; other site
502801005368	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
502801005369	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
502801005370	active site
502801005371	HIGH motif; other site
502801005372	KMSKS motif; other site
502801005373	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
502801005374	tRNA binding surface [nucleotide binding]; other site
502801005375	anticodon binding site; other site
502801005376	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
502801005377	dimer interface [polypeptide binding]; other site
502801005378	putative tRNA-binding site [nucleotide binding]; other site
502801005379	antiporter inner membrane protein; Provisional; Region: PRK11670
502801005380	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
502801005381	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
502801005382	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
502801005383	ATP-binding site [chemical binding]; other site
502801005384	Sugar specificity; other site
502801005385	Pyrimidine base specificity; other site
502801005386	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
502801005387	trimer interface [polypeptide binding]; other site
502801005388	active site
502801005389	putative assembly protein; Provisional; Region: PRK10833
502801005390	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
502801005391	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
502801005392	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
502801005393	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
502801005394	Transporter associated domain; Region: CorC_HlyC; smart01091
502801005395	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
502801005396	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
502801005397	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
502801005398	tyrosine decarboxylase; Region: PLN02880
502801005399	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
502801005400	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801005401	catalytic residue [active]
502801005402	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
502801005403	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
502801005404	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
502801005405	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
502801005406	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
502801005407	IucA / IucC family; Region: IucA_IucC; pfam04183
502801005408	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
502801005409	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
502801005410	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
502801005411	Walker A/P-loop; other site
502801005412	ATP binding site [chemical binding]; other site
502801005413	Q-loop/lid; other site
502801005414	ABC transporter signature motif; other site
502801005415	Walker B; other site
502801005416	D-loop; other site
502801005417	H-loop/switch region; other site
502801005418	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
502801005419	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
502801005420	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801005421	ABC-ATPase subunit  interface; other site
502801005422	dimer interface [polypeptide binding]; other site
502801005423	putative PBP binding regions; other site
502801005424	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
502801005425	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801005426	ABC-ATPase subunit  interface; other site
502801005427	dimer interface [polypeptide binding]; other site
502801005428	putative PBP binding regions; other site
502801005429	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
502801005430	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
502801005431	siderophore binding site; other site
502801005432	Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism]; Region: FhuE; COG4773
502801005433	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801005434	N-terminal plug; other site
502801005435	ligand-binding site [chemical binding]; other site
502801005436	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
502801005437	IucA / IucC family; Region: IucA_IucC; pfam04183
502801005438	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
502801005439	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
502801005440	active site
502801005441	tetramer interface; other site
502801005442	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
502801005443	active site
502801005444	tetramer interface; other site
502801005445	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
502801005446	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
502801005447	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
502801005448	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
502801005449	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
502801005450	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
502801005451	metal binding site [ion binding]; metal-binding site
502801005452	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
502801005453	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
502801005454	substrate binding site [chemical binding]; other site
502801005455	glutamase interaction surface [polypeptide binding]; other site
502801005456	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
502801005457	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
502801005458	catalytic residues [active]
502801005459	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
502801005460	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
502801005461	putative active site [active]
502801005462	oxyanion strand; other site
502801005463	catalytic triad [active]
502801005464	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
502801005465	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801005466	active site
502801005467	motif I; other site
502801005468	motif II; other site
502801005469	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
502801005470	putative active site pocket [active]
502801005471	4-fold oligomerization interface [polypeptide binding]; other site
502801005472	metal binding residues [ion binding]; metal-binding site
502801005473	3-fold/trimer interface [polypeptide binding]; other site
502801005474	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
502801005475	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801005476	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801005477	homodimer interface [polypeptide binding]; other site
502801005478	catalytic residue [active]
502801005479	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
502801005480	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
502801005481	NAD binding site [chemical binding]; other site
502801005482	dimerization interface [polypeptide binding]; other site
502801005483	product binding site; other site
502801005484	substrate binding site [chemical binding]; other site
502801005485	zinc binding site [ion binding]; other site
502801005486	catalytic residues [active]
502801005487	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
502801005488	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
502801005489	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
502801005490	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
502801005491	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
502801005492	putative NAD(P) binding site [chemical binding]; other site
502801005493	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801005494	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801005495	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801005496	TM-ABC transporter signature motif; other site
502801005497	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801005498	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801005499	Walker A/P-loop; other site
502801005500	ATP binding site [chemical binding]; other site
502801005501	Q-loop/lid; other site
502801005502	ABC transporter signature motif; other site
502801005503	Walker B; other site
502801005504	D-loop; other site
502801005505	H-loop/switch region; other site
502801005506	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801005507	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
502801005508	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
502801005509	putative active site [active]
502801005510	metal binding site [ion binding]; metal-binding site
502801005511	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
502801005512	exonuclease I; Provisional; Region: sbcB; PRK11779
502801005513	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
502801005514	active site
502801005515	catalytic site [active]
502801005516	substrate binding site [chemical binding]; other site
502801005517	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
502801005518	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801005519	NAD(P) binding site [chemical binding]; other site
502801005520	active site
502801005521	hypothetical protein; Provisional; Region: PRK05423
502801005522	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
502801005523	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
502801005524	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
502801005525	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
502801005526	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
502801005527	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801005528	putative substrate translocation pore; other site
502801005529	Predicted thiol-disulfide oxidoreductase [General function    prediction only]; Region: COG3011
502801005530	3-ketoacyl-(acyl-carrier-protein) reductase; Reviewed; Region: PRK12826
502801005531	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
502801005532	NAD binding site [chemical binding]; other site
502801005533	homotetramer interface [polypeptide binding]; other site
502801005534	homodimer interface [polypeptide binding]; other site
502801005535	active site
502801005536	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
502801005537	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
502801005538	Human rTS beta is encoded by the rTS gene which, through alternative RNA splicing, also encodes rTS alpha whose mRNA is complementary to thymidylate synthase mRNA. rTS beta expression is associated with the production of small molecules that appear to...; Region: rTSbeta_L-fuconate_dehydratase; cd03324
502801005539	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
502801005540	putative active site pocket [active]
502801005541	metal binding site [ion binding]; metal-binding site
502801005542	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
502801005543	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
502801005544	phosphate binding site [ion binding]; other site
502801005545	argininosuccinate synthase; Validated; Region: PRK05370
502801005546	MATE family multidrug exporter; Provisional; Region: PRK10189
502801005547	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
502801005548	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801005549	Major Facilitator Superfamily; Region: MFS_1; pfam07690
502801005550	putative substrate translocation pore; other site
502801005551	Catalytic domain of Helicobacter pylori peptidoglycan deacetylase (HpPgdA) and similar proteins; Region: CE4_HpPgdA_like; cd10938
502801005552	active site
502801005553	catalytic site [active]
502801005554	Zn binding site [ion binding]; other site
502801005555	tetramer interface [polypeptide binding]; other site
502801005556	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
502801005557	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
502801005558	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
502801005559	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
502801005560	DNA-binding interface [nucleotide binding]; DNA binding site
502801005561	Integrase core domain; Region: rve; pfam00665
502801005562	transposase/IS protein; Provisional; Region: PRK09183
502801005563	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801005564	Walker A motif; other site
502801005565	ATP binding site [chemical binding]; other site
502801005566	Walker B motif; other site
502801005567	Haemolysin expression modulating protein; Region: HHA; cl11501
502801005568	phage/conjugal plasmid C-4 type zinc finger protein, TraR family; Region: C4_traR_proteo; TIGR02419
502801005569	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
502801005570	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
502801005571	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
502801005572	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801005573	N-terminal plug; other site
502801005574	ligand-binding site [chemical binding]; other site
502801005575	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
502801005576	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
502801005577	acyl-activating enzyme (AAE) consensus motif; other site
502801005578	active site
502801005579	AMP binding site [chemical binding]; other site
502801005580	substrate binding site [chemical binding]; other site
502801005581	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
502801005582	Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PchG; COG4693
502801005583	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
502801005584	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
502801005585	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
502801005586	active site
502801005587	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
502801005588	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
502801005589	Methyltransferase domain; Region: Methyltransf_12; pfam08242
502801005590	ketoreductase (KR) and fatty acid synthase (FAS), complex (x) SDRs; Region: KR_FAS_SDR_x; cd05274
502801005591	KR domain; Region: KR; pfam08659
502801005592	NADP binding site [chemical binding]; other site
502801005593	active site
502801005594	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
502801005595	Condensation domain; Region: Condensation; pfam00668
502801005596	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
502801005597	Nonribosomal peptide synthase; Region: NRPS; pfam08415
502801005598	Methyltransferase domain; Region: Methyltransf_12; pfam08242
502801005599	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
502801005600	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
502801005601	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
502801005602	Condensation domain; Region: Condensation; pfam00668
502801005603	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
502801005604	Nonribosomal peptide synthase; Region: NRPS; pfam08415
502801005605	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
502801005606	acyl-activating enzyme (AAE) consensus motif; other site
502801005607	AMP binding site [chemical binding]; other site
502801005608	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801005609	S-adenosylmethionine binding site [chemical binding]; other site
502801005610	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
502801005611	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
502801005612	Condensation domain; Region: Condensation; pfam00668
502801005613	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
502801005614	Nonribosomal peptide synthase; Region: NRPS; pfam08415
502801005615	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
502801005616	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
502801005617	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801005618	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801005619	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
502801005620	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801005621	Walker A/P-loop; other site
502801005622	ATP binding site [chemical binding]; other site
502801005623	Q-loop/lid; other site
502801005624	ABC transporter signature motif; other site
502801005625	Walker B; other site
502801005626	D-loop; other site
502801005627	H-loop/switch region; other site
502801005628	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
502801005629	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801005630	Walker A/P-loop; other site
502801005631	ATP binding site [chemical binding]; other site
502801005632	Q-loop/lid; other site
502801005633	ABC transporter signature motif; other site
502801005634	Walker B; other site
502801005635	D-loop; other site
502801005636	H-loop/switch region; other site
502801005637	muropeptide transporter; Validated; Region: ampG; cl17669
502801005638	salicylate synthase Irp9; Reviewed; Region: PRK06772
502801005639	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
502801005640	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
502801005641	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801005642	active site
502801005643	phosphorylation site [posttranslational modification]
502801005644	intermolecular recognition site; other site
502801005645	dimerization interface [polypeptide binding]; other site
502801005646	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801005647	DNA binding residues [nucleotide binding]
502801005648	dimerization interface [polypeptide binding]; other site
502801005649	DctM-like transporters; Region: DctM; pfam06808
502801005650	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
502801005651	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
502801005652	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
502801005653	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
502801005654	Phosphopantetheinyl transferase component of siderophore synthetase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntD; COG2977
502801005655	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
502801005656	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
502801005657	Melibiase; Region: Melibiase; pfam02065
502801005658	galactoside permease; Reviewed; Region: lacY; PRK09528
502801005659	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801005660	putative substrate translocation pore; other site
502801005661	Transcriptional regulators [Transcription]; Region: PurR; COG1609
502801005662	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801005663	DNA binding site [nucleotide binding]
502801005664	domain linker motif; other site
502801005665	Ligand-binding domain of DNA transcription repressors specific for raffinose (RafR) and alpha-glucosides (AglR) which are members of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AglR_RafR_like; cd06271
502801005666	ligand binding site [chemical binding]; other site
502801005667	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
502801005668	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2350
502801005669	Serine/threonine protein kinase involved in cell cycle control [Signal transduction mechanisms / Cell division and chromosome partitioning]; Region: RIO1; COG1718
502801005670	RIO kinase family; RIO1, RIO3 and similar proteins, catalytic domain. The RIO kinase catalytic domain family is part of a larger superfamily, that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein...; Region: RIO1_like; cd05145
502801005671	ATP binding site [chemical binding]; other site
502801005672	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
502801005673	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801005674	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
502801005675	Walker A/P-loop; other site
502801005676	ATP binding site [chemical binding]; other site
502801005677	Q-loop/lid; other site
502801005678	ABC transporter signature motif; other site
502801005679	Walker B; other site
502801005680	D-loop; other site
502801005681	H-loop/switch region; other site
502801005682	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
502801005683	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801005684	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
502801005685	YobH-like protein; Region: YobH; pfam13996
502801005686	YebO-like protein; Region: YebO; pfam13974
502801005687	Protein of unknown function (DUF2591); Region: DUF2591; pfam10765
502801005688	Protein of unknown function (DUF4060); Region: DUF4060; pfam13269
502801005689	aromatic amino acid transporter; Provisional; Region: PRK10238
502801005690	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
502801005691	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
502801005692	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
502801005693	DNA-binding site [nucleotide binding]; DNA binding site
502801005694	RNA-binding motif; other site
502801005695	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
502801005696	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
502801005697	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
502801005698	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801005699	S-adenosylmethionine binding site [chemical binding]; other site
502801005700	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
502801005701	PAS domain; Region: PAS_9; pfam13426
502801005702	putative active site [active]
502801005703	heme pocket [chemical binding]; other site
502801005704	PAS domain S-box; Region: sensory_box; TIGR00229
502801005705	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
502801005706	putative active site [active]
502801005707	heme pocket [chemical binding]; other site
502801005708	PAS domain S-box; Region: sensory_box; TIGR00229
502801005709	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
502801005710	putative active site [active]
502801005711	heme pocket [chemical binding]; other site
502801005712	PAS fold; Region: PAS; pfam00989
502801005713	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
502801005714	putative active site [active]
502801005715	heme pocket [chemical binding]; other site
502801005716	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
502801005717	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
502801005718	metal binding site [ion binding]; metal-binding site
502801005719	active site
502801005720	I-site; other site
502801005721	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
502801005722	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801005723	N-terminal plug; other site
502801005724	ligand-binding site [chemical binding]; other site
502801005725	hypothetical protein; Provisional; Region: PRK11469
502801005726	Domain of unknown function DUF; Region: DUF204; pfam02659
502801005727	Domain of unknown function DUF; Region: DUF204; pfam02659
502801005728	hypothetical protein; Provisional; Region: PRK02913
502801005729	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
502801005730	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
502801005731	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
502801005732	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
502801005733	active pocket/dimerization site; other site
502801005734	active site
502801005735	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
502801005736	active site
502801005737	phosphorylation site [posttranslational modification]
502801005738	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
502801005739	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
502801005740	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
502801005741	Transporter associated domain; Region: CorC_HlyC; smart01091
502801005742	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
502801005743	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
502801005744	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
502801005745	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303
502801005746	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
502801005747	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
502801005748	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
502801005749	NAD binding site [chemical binding]; other site
502801005750	catalytic residues [active]
502801005751	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
502801005752	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
502801005753	putative active site [active]
502801005754	putative metal binding site [ion binding]; other site
502801005755	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
502801005756	trimer interface [polypeptide binding]; other site
502801005757	putative substrate binding pocket [chemical binding]; other site
502801005758	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
502801005759	2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Region: HpaI; TIGR02311
502801005760	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
502801005761	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801005762	putative substrate translocation pore; other site
502801005763	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
502801005764	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
502801005765	4-hydroxyphenylacetate 3-monooxygenase, reductase component; Region: HpaC; TIGR02296
502801005766	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
502801005767	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
502801005768	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
502801005769	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
502801005770	putative active site [active]
502801005771	putative CoA binding site [chemical binding]; other site
502801005772	nudix motif; other site
502801005773	metal binding site [ion binding]; metal-binding site
502801005774	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
502801005775	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
502801005776	chorismate binding enzyme; Region: Chorismate_bind; cl10555
502801005777	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3140
502801005778	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
502801005779	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801005780	ATP-grasp domain; Region: ATP-grasp; pfam02222
502801005781	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
502801005782	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
502801005783	ATP binding site [chemical binding]; other site
502801005784	Mg++ binding site [ion binding]; other site
502801005785	motif III; other site
502801005786	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801005787	nucleotide binding region [chemical binding]; other site
502801005788	ATP-binding site [chemical binding]; other site
502801005789	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
502801005790	YebG protein; Region: YebG; pfam07130
502801005791	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
502801005792	hypothetical protein; Provisional; Region: PRK13680
502801005793	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
502801005794	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
502801005795	proline iminopeptidase, Neisseria-type subfamily; Region: pro_imino_pep_1; TIGR01249
502801005796	Serine hydrolase; Region: Ser_hydrolase; cl17834
502801005797	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
502801005798	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
502801005799	Ferritin-like domain; Region: Ferritin; pfam00210
502801005800	ferroxidase diiron center [ion binding]; other site
502801005801	Uncharacterized protein, homolog of Cu resistance protein CopC [General function prediction only]; Region: CopC; COG2372
502801005802	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
502801005803	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
502801005804	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
502801005805	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
502801005806	MULE transposase domain; Region: MULE; pfam10551
502801005807	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK12468
502801005808	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
502801005809	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
502801005810	FHIPEP family; Region: FHIPEP; pfam00771
502801005811	Flagellar protein FlhE; Region: FlhE; pfam06366
502801005812	putative invasin; Provisional; Region: PRK10177
502801005813	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
502801005814	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
502801005815	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
502801005816	Invasin, domain 3; Region: Invasin_D3; pfam09134
502801005817	Intimin C-type lectin domain; Region: Intimin_C; pfam07979
502801005818	Flagellar biosynthesis/type III secretory pathway chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3418
502801005819	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
502801005820	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
502801005821	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
502801005822	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
502801005823	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
502801005824	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
502801005825	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
502801005826	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
502801005827	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
502801005828	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
502801005829	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
502801005830	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
502801005831	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
502801005832	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
502801005833	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
502801005834	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
502801005835	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
502801005836	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
502801005837	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
502801005838	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
502801005839	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
502801005840	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
502801005841	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
502801005842	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
502801005843	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
502801005844	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
502801005845	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
502801005846	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
502801005847	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
502801005848	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
502801005849	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
502801005850	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
502801005851	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
502801005852	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
502801005853	short chain dehydrogenase; Validated; Region: PRK08324
502801005854	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; smart01007
502801005855	rhamnulose-1-phosphate aldolase/alcohol dehydrogenase, classical (c) SDRs; Region: R1PA_ADH_SDR_c; cd08943
502801005856	putative NAD(P) binding site [chemical binding]; other site
502801005857	active site
502801005858	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801005859	TM-ABC transporter signature motif; other site
502801005860	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
502801005861	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
502801005862	ligand binding site [chemical binding]; other site
502801005863	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801005864	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801005865	Walker A/P-loop; other site
502801005866	ATP binding site [chemical binding]; other site
502801005867	Q-loop/lid; other site
502801005868	ABC transporter signature motif; other site
502801005869	Walker B; other site
502801005870	D-loop; other site
502801005871	H-loop/switch region; other site
502801005872	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801005873	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801005874	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801005875	TM-ABC transporter signature motif; other site
502801005876	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
502801005877	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
502801005878	substrate binding site [chemical binding]; other site
502801005879	ATP binding site [chemical binding]; other site
502801005880	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
502801005881	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
502801005882	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
502801005883	Flagellar biogenesis protein [Cell motility and secretion]; Region: FliO; COG3190
502801005884	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
502801005885	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
502801005886	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
502801005887	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
502801005888	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
502801005889	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
502801005890	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
502801005891	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
502801005892	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
502801005893	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
502801005894	Walker A motif/ATP binding site; other site
502801005895	Walker B motif; other site
502801005896	flagellar assembly protein H; Validated; Region: fliH; PRK05687
502801005897	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
502801005898	Flagellar assembly protein FliH; Region: FliH; pfam02108
502801005899	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
502801005900	FliG C-terminal domain; Region: FliG_C; pfam01706
502801005901	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
502801005902	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
502801005903	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
502801005904	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
502801005905	death-on-curing family protein; Region: DOC_P1; TIGR01550
502801005906	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]; Region: AlkA; COG0122
502801005907	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
502801005908	minor groove reading motif; other site
502801005909	helix-hairpin-helix signature motif; other site
502801005910	active site
502801005911	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
502801005912	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
502801005913	Zn2+ binding site [ion binding]; other site
502801005914	Mg2+ binding site [ion binding]; other site
502801005915	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
502801005916	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
502801005917	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801005918	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
502801005919	flagellar protein FliS; Validated; Region: fliS; PRK05685
502801005920	flagellar capping protein; Reviewed; Region: fliD; PRK08032
502801005921	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
502801005922	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
502801005923	flagellin; Validated; Region: PRK06819
502801005924	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
502801005925	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
502801005926	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
502801005927	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
502801005928	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
502801005929	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
502801005930	DNA binding residues [nucleotide binding]
502801005931	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
502801005932	D-cysteine desulfhydrase; Validated; Region: PRK03910
502801005933	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
502801005934	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801005935	catalytic residue [active]
502801005936	cystine transporter subunit; Provisional; Region: PRK11260
502801005937	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801005938	substrate binding pocket [chemical binding]; other site
502801005939	membrane-bound complex binding site; other site
502801005940	hinge residues; other site
502801005941	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
502801005942	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801005943	dimer interface [polypeptide binding]; other site
502801005944	conserved gate region; other site
502801005945	putative PBP binding loops; other site
502801005946	ABC-ATPase subunit interface; other site
502801005947	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
502801005948	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
502801005949	Walker A/P-loop; other site
502801005950	ATP binding site [chemical binding]; other site
502801005951	Q-loop/lid; other site
502801005952	ABC transporter signature motif; other site
502801005953	Walker B; other site
502801005954	D-loop; other site
502801005955	H-loop/switch region; other site
502801005956	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801005957	MarR family; Region: MarR_2; cl17246
502801005958	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
502801005959	Predicted transcriptional regulator [Transcription]; Region: COG3905
502801005960	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
502801005961	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
502801005962	Glutamate binding site [chemical binding]; other site
502801005963	NAD binding site [chemical binding]; other site
502801005964	catalytic residues [active]
502801005965	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
502801005966	Na binding site [ion binding]; other site
502801005967	Iron permease FTR1 family; Region: FTR1; cl00475
502801005968	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
502801005969	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
502801005970	Imelysin; Region: Peptidase_M75; pfam09375
502801005971	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
502801005972	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
502801005973	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
502801005974	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
502801005975	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
502801005976	Kelch motif; Region: Kelch_1; pfam01344
502801005977	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
502801005978	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
502801005979	GlpM protein; Region: GlpM; pfam06942
502801005980	hypothetical protein; Provisional; Region: PRK10613
502801005981	response regulator; Provisional; Region: PRK09483
502801005982	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801005983	active site
502801005984	phosphorylation site [posttranslational modification]
502801005985	intermolecular recognition site; other site
502801005986	dimerization interface [polypeptide binding]; other site
502801005987	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801005988	DNA binding residues [nucleotide binding]
502801005989	dimerization interface [polypeptide binding]; other site
502801005990	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
502801005991	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
502801005992	GIY-YIG motif/motif A; other site
502801005993	active site
502801005994	catalytic site [active]
502801005995	putative DNA binding site [nucleotide binding]; other site
502801005996	metal binding site [ion binding]; metal-binding site
502801005997	UvrB/uvrC motif; Region: UVR; pfam02151
502801005998	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
502801005999	Helix-hairpin-helix motif; Region: HHH; pfam00633
502801006000	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
502801006001	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
502801006002	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
502801006003	tail protein; Provisional; Region: D; PHA02561
502801006004	Phage P2 GpU; Region: Phage_P2_GpU; pfam06995
502801006005	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
502801006006	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
502801006007	major tail tube protein; Provisional; Region: FII; PHA02600
502801006008	major tail sheath protein; Provisional; Region: FI; PHA02560
502801006009	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
502801006010	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
502801006011	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
502801006012	baseplate assembly protein; Provisional; Region: J; PHA02568
502801006013	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
502801006014	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
502801006015	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
502801006016	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
502801006017	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
502801006018	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
502801006019	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
502801006020	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
502801006021	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
502801006022	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
502801006023	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
502801006024	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
502801006025	terminase endonuclease subunit; Provisional; Region: M; PHA02537
502801006026	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
502801006027	capsid protein; Provisional; Region: N; PHA02538
502801006028	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
502801006029	terminase ATPase subunit; Provisional; Region: P; PHA02535
502801006030	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
502801006031	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
502801006032	portal vertex protein; Provisional; Region: Q; PHA02536
502801006033	Phage portal protein; Region: Phage_portal; pfam04860
502801006034	Dock Homology Region 2, a GEF domain, of Dedicator of Cytokinesis proteins; Region: DHR2_DOCK; cl06123
502801006035	nucleotide sensor; other site
502801006036	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
502801006037	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
502801006038	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
502801006039	cofactor binding site; other site
502801006040	DNA binding site [nucleotide binding]
502801006041	substrate interaction site [chemical binding]; other site
502801006042	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
502801006043	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
502801006044	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
502801006045	active site
502801006046	catalytic site [active]
502801006047	substrate binding site [chemical binding]; other site
502801006048	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in uncharacterized protein from Archaeoglobus fulgidus (Af0060) and its bacterial homologs; Region: NTP-PPase_Af0060_like; cd11533
502801006049	homodimer interface [polypeptide binding]; other site
502801006050	metal binding site [ion binding]; metal-binding site
502801006051	Domain of unknown function (DUF2828); Region: DUF2828; pfam11443
502801006052	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
502801006053	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
502801006054	non-specific DNA binding site [nucleotide binding]; other site
502801006055	salt bridge; other site
502801006056	sequence-specific DNA binding site [nucleotide binding]; other site
502801006057	Domain of unknown function (DUF4041); Region: DUF4041; pfam13250
502801006058	Bacterial protein of unknown function (DUF922); Region: DUF922; cl02415
502801006059	This entry represents the putative helicase A859L; Region: T5orf172; smart00974
502801006060	integrase; Provisional; Region: int; PHA02601
502801006061	Sm and related proteins; Region: Sm_like; cl00259
502801006062	integrase; Provisional; Region: int; PHA02601
502801006063	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
502801006064	DNA binding site [nucleotide binding]
502801006065	Int/Topo IB signature motif; other site
502801006066	active site
502801006067	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
502801006068	DNA binding site [nucleotide binding]
502801006069	active site
502801006070	Int/Topo IB signature motif; other site
502801006071	Protein of unknown function (DUF796); Region: DUF796; cl01226
502801006072	Homeodomain-like domain; Region: HTH_32; pfam13565
502801006073	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
502801006074	Integrase core domain; Region: rve; pfam00665
502801006075	Integrase core domain; Region: rve_3; pfam13683
502801006076	Transposase; Region: HTH_Tnp_1; cl17663
502801006077	Major Facilitator Superfamily; Region: MFS_1; pfam07690
502801006078	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801006079	putative substrate translocation pore; other site
502801006080	hypothetical protein; Provisional; Region: PRK08328
502801006081	ThiF family; Region: ThiF; pfam00899
502801006082	ATP binding site [chemical binding]; other site
502801006083	Methyltransferase domain; Region: Methyltransf_31; pfam13847
502801006084	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801006085	S-adenosylmethionine binding site [chemical binding]; other site
502801006086	Methyltransferase domain; Region: Methyltransf_23; pfam13489
502801006087	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801006088	S-adenosylmethionine binding site [chemical binding]; other site
502801006089	Methyltransferase domain; Region: Methyltransf_31; pfam13847
502801006090	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801006091	S-adenosylmethionine binding site [chemical binding]; other site
502801006092	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme MccE; Region: PLPDE_III_MccE_like; cd06841
502801006093	dimer interface [polypeptide binding]; other site
502801006094	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
502801006095	active site
502801006096	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
502801006097	catalytic residues [active]
502801006098	substrate binding site [chemical binding]; other site
502801006099	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
502801006100	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
502801006101	Transposase; Region: HTH_Tnp_1; pfam01527
502801006102	Homeodomain-like domain; Region: HTH_32; pfam13565
502801006103	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
502801006104	Integrase core domain; Region: rve; pfam00665
502801006105	Integrase core domain; Region: rve_3; pfam13683
502801006106	Transposase; Region: HTH_Tnp_1; cl17663
502801006107	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
502801006108	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
502801006109	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
502801006110	Phage baseplate assembly protein W [General function prediction only]; Region: COG3628
502801006111	Phage-related baseplate assembly protein; Region: Phage_base_V; cl17812
502801006112	Protein of unknown function (DUF497); Region: DUF497; pfam04365
502801006113	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3514
502801006114	TIR domain; Region: TIR_2; pfam13676
502801006115	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
502801006116	MULE transposase domain; Region: MULE; pfam10551
502801006117	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
502801006118	Integrase core domain; Region: rve_3; cl15866
502801006119	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
502801006120	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801006121	DNA-binding site [nucleotide binding]; DNA binding site
502801006122	UTRA domain; Region: UTRA; pfam07702
502801006123	N-acetylmannosamine kinase; Provisional; Region: PRK05082
502801006124	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
502801006125	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
502801006126	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
502801006127	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
502801006128	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
502801006129	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801006130	dimer interface [polypeptide binding]; other site
502801006131	conserved gate region; other site
502801006132	putative PBP binding loops; other site
502801006133	ABC-ATPase subunit interface; other site
502801006134	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
502801006135	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801006136	dimer interface [polypeptide binding]; other site
502801006137	conserved gate region; other site
502801006138	putative PBP binding loops; other site
502801006139	ABC-ATPase subunit interface; other site
502801006140	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
502801006141	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801006142	Walker A/P-loop; other site
502801006143	ATP binding site [chemical binding]; other site
502801006144	Q-loop/lid; other site
502801006145	ABC transporter signature motif; other site
502801006146	Walker B; other site
502801006147	D-loop; other site
502801006148	H-loop/switch region; other site
502801006149	TOBE domain; Region: TOBE_2; pfam08402
502801006150	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
502801006151	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801006152	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
502801006153	Fimbrial protein; Region: Fimbrial; cl01416
502801006154	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
502801006155	PapC N-terminal domain; Region: PapC_N; pfam13954
502801006156	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
502801006157	PapC C-terminal domain; Region: PapC_C; pfam13953
502801006158	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
502801006159	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801006160	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
502801006161	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
502801006162	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
502801006163	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801006164	substrate binding pocket [chemical binding]; other site
502801006165	membrane-bound complex binding site; other site
502801006166	hinge residues; other site
502801006167	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801006168	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
502801006169	substrate binding pocket [chemical binding]; other site
502801006170	membrane-bound complex binding site; other site
502801006171	hinge residues; other site
502801006172	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
502801006173	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801006174	dimer interface [polypeptide binding]; other site
502801006175	phosphorylation site [posttranslational modification]
502801006176	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801006177	ATP binding site [chemical binding]; other site
502801006178	Mg2+ binding site [ion binding]; other site
502801006179	G-X-G motif; other site
502801006180	Response regulator receiver domain; Region: Response_reg; pfam00072
502801006181	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801006182	active site
502801006183	phosphorylation site [posttranslational modification]
502801006184	intermolecular recognition site; other site
502801006185	dimerization interface [polypeptide binding]; other site
502801006186	Hpt domain; Region: Hpt; pfam01627
502801006187	transcriptional regulator FimZ; Provisional; Region: PRK09935
502801006188	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801006189	active site
502801006190	phosphorylation site [posttranslational modification]
502801006191	intermolecular recognition site; other site
502801006192	dimerization interface [polypeptide binding]; other site
502801006193	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801006194	DNA binding residues [nucleotide binding]
502801006195	dimerization interface [polypeptide binding]; other site
502801006196	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
502801006197	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
502801006198	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
502801006199	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
502801006200	putative active site [active]
502801006201	putative catalytic site [active]
502801006202	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
502801006203	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
502801006204	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801006205	The C-terminal substrate binding domain of LysR-type transcrptional regulator BudR, which is responsible for activation of the expression of the butanediol operon genes; contains the type 2 periplasmic binding fold; Region: PBP2_BudR; cd08451
502801006206	putative dimerization interface [polypeptide binding]; other site
502801006207	putative substrate binding pocket [chemical binding]; other site
502801006208	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
502801006209	benzoate transport; Region: 2A0115; TIGR00895
502801006210	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801006211	putative substrate translocation pore; other site
502801006212	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
502801006213	2-pyrone-4,6-dicarboxylic acid (PDC) hydrolase hydrolyzes PDC to yield 4-oxalomesaconic acid (OMA) or its tautomer, 4-carboxy-2-hydroxymuconic acid (CHM). This reaction is part of the protocatechuate (PCA) 4,5-cleavage pathway. PCA is one of the most...; Region: PDC_hydrolase; cd01311
502801006214	active site
502801006215	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801006216	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801006217	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
502801006218	dimerization interface [polypeptide binding]; other site
502801006219	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK12456
502801006220	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
502801006221	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801006222	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801006223	homodimer interface [polypeptide binding]; other site
502801006224	catalytic residue [active]
502801006225	L-asparagine permease; Provisional; Region: PRK15049
502801006226	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
502801006227	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
502801006228	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
502801006229	glutaminase; Reviewed; Region: PRK12356
502801006230	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
502801006231	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801006232	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801006233	High-affinity Fe2+/Pb2+ permease [Inorganic ion transport and metabolism]; Region: FTR1; COG0672
502801006234	Uncharacterized protein probably involved in high-affinity Fe2+ transport [Inorganic ion transport and metabolism]; Region: Tpd; COG3470
502801006235	Predicted membrane protein [Function unknown]; Region: COG4393
502801006236	Predicted membrane protein (DUF2318); Region: DUF2318; pfam10080
502801006237	Uncharacterized conserved protein [Function unknown]; Region: COG3350
502801006238	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
502801006239	FtsX-like permease family; Region: FtsX; pfam02687
502801006240	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
502801006241	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
502801006242	FtsX-like permease family; Region: FtsX; pfam02687
502801006243	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
502801006244	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
502801006245	Walker A/P-loop; other site
502801006246	ATP binding site [chemical binding]; other site
502801006247	Q-loop/lid; other site
502801006248	ABC transporter signature motif; other site
502801006249	Walker B; other site
502801006250	D-loop; other site
502801006251	H-loop/switch region; other site
502801006252	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
502801006253	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
502801006254	catalytic residues [active]
502801006255	Cytochrome c553 [Energy production and conversion]; Region: COG2863
502801006256	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
502801006257	tellurite resistance protein TehB; Provisional; Region: PRK12335
502801006258	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801006259	S-adenosylmethionine binding site [chemical binding]; other site
502801006260	putative endopeptidase; Provisional; Region: PRK14576
502801006261	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
502801006262	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
502801006263	active site
502801006264	outer membrane protein; Provisional; Region: hmsH; PRK14574
502801006265	outer membrane N-deacetylase; Provisional; Region: hmsF; PRK14581
502801006266	N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964
502801006267	putative active site [active]
502801006268	putative metal binding site [ion binding]; other site
502801006269	N-glycosyltransferase; Provisional; Region: hmsR; PRK14583
502801006270	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
502801006271	DXD motif; other site
502801006272	hemin storage system protein; Provisional; Region: hmsS; PRK14584
502801006273	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
502801006274	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
502801006275	hypothetical protein; Provisional; Region: PRK10536
502801006276	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
502801006277	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
502801006278	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
502801006279	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
502801006280	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
502801006281	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801006282	dimerization interface [polypeptide binding]; other site
502801006283	Histidine kinase; Region: HisKA_3; pfam07730
502801006284	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801006285	ATP binding site [chemical binding]; other site
502801006286	Mg2+ binding site [ion binding]; other site
502801006287	G-X-G motif; other site
502801006288	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
502801006289	DNA-binding site [nucleotide binding]; DNA binding site
502801006290	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
502801006291	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801006292	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801006293	homodimer interface [polypeptide binding]; other site
502801006294	catalytic residue [active]
502801006295	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
502801006296	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
502801006297	inhibitor-cofactor binding pocket; inhibition site
502801006298	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801006299	catalytic residue [active]
502801006300	arginine succinyltransferase; Provisional; Region: PRK10456
502801006301	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
502801006302	succinylglutamic semialdehyde dehydrogenase; Region: arg_catab_astD; TIGR03240
502801006303	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
502801006304	NAD(P) binding site [chemical binding]; other site
502801006305	catalytic residues [active]
502801006306	succinylarginine dihydrolase; Provisional; Region: PRK13281
502801006307	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
502801006308	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
502801006309	putative active site [active]
502801006310	Zn binding site [ion binding]; other site
502801006311	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
502801006312	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
502801006313	trimer interface [polypeptide binding]; other site
502801006314	eyelet of channel; other site
502801006315	transposase/IS protein; Provisional; Region: PRK09183
502801006316	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801006317	Walker A motif; other site
502801006318	ATP binding site [chemical binding]; other site
502801006319	Walker B motif; other site
502801006320	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
502801006321	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
502801006322	DNA-binding interface [nucleotide binding]; DNA binding site
502801006323	Integrase core domain; Region: rve; pfam00665
502801006324	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
502801006325	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
502801006326	N-formylglutamate amidohydrolase; Region: hutG_amidohyd; TIGR02017
502801006327	imidazolonepropionase; Validated; Region: PRK09356
502801006328	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
502801006329	active site
502801006330	histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018
502801006331	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801006332	DNA-binding site [nucleotide binding]; DNA binding site
502801006333	UTRA domain; Region: UTRA; pfam07702
502801006334	N-formimino-L-glutamate deiminase; Validated; Region: PRK09229
502801006335	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_E; cd01313
502801006336	active site
502801006337	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3758
502801006338	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
502801006339	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
502801006340	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK07204
502801006341	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
502801006342	dimer interface [polypeptide binding]; other site
502801006343	active site
502801006344	CoA binding pocket [chemical binding]; other site
502801006345	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
502801006346	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801006347	NAD(P) binding site [chemical binding]; other site
502801006348	active site
502801006349	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
502801006350	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
502801006351	putative adenylate-forming enzyme; Region: aden_form_hyp; TIGR02304
502801006352	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
502801006353	extended (e) SDRs; Region: SDR_e; cd08946
502801006354	NAD(P) binding site [chemical binding]; other site
502801006355	active site
502801006356	substrate binding site [chemical binding]; other site
502801006357	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
502801006358	active site
502801006359	Glycosyl transferase family 21; Region: Glyco_transf_21; pfam13506
502801006360	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
502801006361	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
502801006362	active site
502801006363	TDP-binding site; other site
502801006364	acceptor substrate-binding pocket; other site
502801006365	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
502801006366	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
502801006367	Sel1-like repeats; Region: SEL1; smart00671
502801006368	Sel1-like repeats; Region: SEL1; smart00671
502801006369	Sel1-like repeats; Region: SEL1; smart00671
502801006370	Domain of unknown function (DUF4034); Region: DUF4034; pfam13226
502801006371	hypothetical protein; Provisional; Region: PRK09273
502801006372	Ribose 5-phosphate isomerase RpiB [Carbohydrate transport and metabolism]; Region: RpiB; COG0698
502801006373	Ribose-5-phosphate isomerase; Region: DUF3666; pfam12408
502801006374	Methyltransferase domain; Region: Methyltransf_12; pfam08242
502801006375	classical (c) SDRs; Region: SDR_c; cd05233
502801006376	3-ketoacyl-(acyl-carrier-protein) reductase; Reviewed; Region: PRK12826
502801006377	NAD(P) binding site [chemical binding]; other site
502801006378	active site
502801006379	Uncharacterized conserved protein (DUF2303); Region: DUF2303; cl02338
502801006380	HEAT repeats; Region: HEAT_2; pfam13646
502801006381	Uncharacterized enzymes similar to novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like-3; cd12810
502801006382	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
502801006383	catalytic site [active]
502801006384	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
502801006385	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
502801006386	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
502801006387	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801006388	dimerization interface [polypeptide binding]; other site
502801006389	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801006390	dimer interface [polypeptide binding]; other site
502801006391	phosphorylation site [posttranslational modification]
502801006392	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801006393	ATP binding site [chemical binding]; other site
502801006394	Mg2+ binding site [ion binding]; other site
502801006395	G-X-G motif; other site
502801006396	heavy metal response regulator; Region: cztR_silR_copR; TIGR01387
502801006397	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801006398	active site
502801006399	phosphorylation site [posttranslational modification]
502801006400	intermolecular recognition site; other site
502801006401	dimerization interface [polypeptide binding]; other site
502801006402	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801006403	DNA binding site [nucleotide binding]
502801006404	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
502801006405	flavodoxin; Provisional; Region: PRK06934
502801006406	Domain of unknown function (DUF4405); Region: DUF4405; pfam14358
502801006407	Protein of unknown function (DUF4087); Region: DUF4087; pfam13316
502801006408	GTP-binding protein YchF; Reviewed; Region: PRK09601
502801006409	YchF GTPase; Region: YchF; cd01900
502801006410	G1 box; other site
502801006411	GTP/Mg2+ binding site [chemical binding]; other site
502801006412	Switch I region; other site
502801006413	G2 box; other site
502801006414	Switch II region; other site
502801006415	G3 box; other site
502801006416	G4 box; other site
502801006417	G5 box; other site
502801006418	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
502801006419	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
502801006420	putative active site [active]
502801006421	catalytic residue [active]
502801006422	hypothetical protein; Provisional; Region: PRK10692
502801006423	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
502801006424	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
502801006425	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
502801006426	active site
502801006427	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
502801006428	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
502801006429	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
502801006430	outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022
502801006431	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
502801006432	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
502801006433	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
502801006434	tRNA; other site
502801006435	putative tRNA binding site [nucleotide binding]; other site
502801006436	putative NADP binding site [chemical binding]; other site
502801006437	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
502801006438	peptide chain release factor 1; Validated; Region: prfA; PRK00591
502801006439	This domain is found in peptide chain release factors; Region: PCRF; smart00937
502801006440	RF-1 domain; Region: RF-1; pfam00472
502801006441	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
502801006442	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
502801006443	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3094
502801006444	hypothetical protein; Provisional; Region: PRK10941
502801006445	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
502801006446	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
502801006447	binding surface
502801006448	TPR motif; other site
502801006449	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
502801006450	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
502801006451	putative transporter; Provisional; Region: PRK11660
502801006452	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
502801006453	Sulfate transporter family; Region: Sulfate_transp; pfam00916
502801006454	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
502801006455	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
502801006456	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial protein Rv2277c and similar proteins; Region: GDPD_Rv2277c_like; cd08580
502801006457	putative active site [active]
502801006458	catalytic site [active]
502801006459	putative metal binding site [ion binding]; other site
502801006460	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
502801006461	hypothetical protein; Provisional; Region: PRK11622
502801006462	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
502801006463	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801006464	dimer interface [polypeptide binding]; other site
502801006465	conserved gate region; other site
502801006466	putative PBP binding loops; other site
502801006467	ABC-ATPase subunit interface; other site
502801006468	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801006469	dimer interface [polypeptide binding]; other site
502801006470	conserved gate region; other site
502801006471	putative PBP binding loops; other site
502801006472	ABC-ATPase subunit interface; other site
502801006473	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
502801006474	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801006475	Walker A/P-loop; other site
502801006476	ATP binding site [chemical binding]; other site
502801006477	Q-loop/lid; other site
502801006478	ABC transporter signature motif; other site
502801006479	Walker B; other site
502801006480	D-loop; other site
502801006481	H-loop/switch region; other site
502801006482	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
502801006483	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
502801006484	active site
502801006485	catalytic site [active]
502801006486	Transcriptional regulators [Transcription]; Region: MarR; COG1846
502801006487	MarR family; Region: MarR_2; pfam12802
502801006488	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
502801006489	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
502801006490	putative hydrolase; Validated; Region: PRK09248
502801006491	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
502801006492	active site
502801006493	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
502801006494	lipoprotein; Provisional; Region: PRK10598
502801006495	multidrug resistance protein MdtH; Provisional; Region: PRK11646
502801006496	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801006497	putative substrate translocation pore; other site
502801006498	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
502801006499	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
502801006500	hypothetical protein; Provisional; Region: PRK11239
502801006501	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
502801006502	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
502801006503	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
502801006504	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
502801006505	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
502801006506	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
502801006507	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
502801006508	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
502801006509	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
502801006510	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
502801006511	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
502801006512	active site
502801006513	HIGH motif; other site
502801006514	KMSK motif region; other site
502801006515	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
502801006516	tRNA binding surface [nucleotide binding]; other site
502801006517	anticodon binding site; other site
502801006518	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
502801006519	putative metal binding site [ion binding]; other site
502801006520	copper homeostasis protein CutC; Provisional; Region: PRK11572
502801006521	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801006522	S-adenosylmethionine binding site [chemical binding]; other site
502801006523	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801006524	S-adenosylmethionine binding site [chemical binding]; other site
502801006525	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
502801006526	hypothetical protein; Provisional; Region: PRK10302
502801006527	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
502801006528	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
502801006529	dimer interface [polypeptide binding]; other site
502801006530	anticodon binding site; other site
502801006531	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
502801006532	homodimer interface [polypeptide binding]; other site
502801006533	motif 1; other site
502801006534	active site
502801006535	motif 2; other site
502801006536	GAD domain; Region: GAD; pfam02938
502801006537	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
502801006538	active site
502801006539	motif 3; other site
502801006540	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
502801006541	nudix motif; other site
502801006542	hypothetical protein; Validated; Region: PRK00110
502801006543	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
502801006544	active site
502801006545	putative DNA-binding cleft [nucleotide binding]; other site
502801006546	dimer interface [polypeptide binding]; other site
502801006547	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
502801006548	RuvA N terminal domain; Region: RuvA_N; pfam01330
502801006549	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
502801006550	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
502801006551	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801006552	Walker A motif; other site
502801006553	ATP binding site [chemical binding]; other site
502801006554	Walker B motif; other site
502801006555	arginine finger; other site
502801006556	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
502801006557	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
502801006558	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801006559	ABC-ATPase subunit  interface; other site
502801006560	dimer interface [polypeptide binding]; other site
502801006561	putative PBP binding regions; other site
502801006562	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
502801006563	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
502801006564	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
502801006565	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
502801006566	metal binding site [ion binding]; metal-binding site
502801006567	putative peptidase; Provisional; Region: PRK11649
502801006568	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
502801006569	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
502801006570	Peptidase family M23; Region: Peptidase_M23; pfam01551
502801006571	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
502801006572	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
502801006573	putative acyl-acceptor binding pocket; other site
502801006574	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801006575	pyruvate kinase; Provisional; Region: PRK05826
502801006576	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
502801006577	domain interfaces; other site
502801006578	active site
502801006579	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
502801006580	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
502801006581	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
502801006582	putative active site [active]
502801006583	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
502801006584	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
502801006585	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
502801006586	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
502801006587	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
502801006588	active site
502801006589	intersubunit interface [polypeptide binding]; other site
502801006590	catalytic residue [active]
502801006591	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
502801006592	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
502801006593	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
502801006594	homotrimer interaction site [polypeptide binding]; other site
502801006595	putative active site [active]
502801006596	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
502801006597	DEAD/DEAH box helicase; Region: DEAD; pfam00270
502801006598	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
502801006599	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
502801006600	Glycoprotease family; Region: Peptidase_M22; pfam00814
502801006601	Starvation-inducible outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: Slp; COG3065
502801006602	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
502801006603	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
502801006604	acyl-activating enzyme (AAE) consensus motif; other site
502801006605	putative AMP binding site [chemical binding]; other site
502801006606	putative active site [active]
502801006607	putative CoA binding site [chemical binding]; other site
502801006608	ribonuclease D; Provisional; Region: PRK10829
502801006609	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
502801006610	catalytic site [active]
502801006611	putative active site [active]
502801006612	putative substrate binding site [chemical binding]; other site
502801006613	HRDC domain; Region: HRDC; pfam00570
502801006614	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
502801006615	cell division inhibitor MinD; Provisional; Region: PRK10818
502801006616	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
502801006617	Switch I; other site
502801006618	Switch II; other site
502801006619	septum formation inhibitor; Reviewed; Region: minC; PRK03511
502801006620	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
502801006621	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
502801006622	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
502801006623	lytic murein transglycosylase; Region: MltB_2; TIGR02283
502801006624	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
502801006625	N-acetyl-D-glucosamine binding site [chemical binding]; other site
502801006626	catalytic residue [active]
502801006627	hypothetical protein; Provisional; Region: PRK10691
502801006628	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
502801006629	hypothetical protein; Provisional; Region: PRK05170
502801006630	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801006631	putative substrate translocation pore; other site
502801006632	Major Facilitator Superfamily; Region: MFS_1; pfam07690
502801006633	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
502801006634	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
502801006635	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801006636	catalytic residue [active]
502801006637	disulfide bond formation protein B; Provisional; Region: PRK01749
502801006638	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
502801006639	fatty acid metabolism regulator; Provisional; Region: PRK04984
502801006640	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801006641	DNA-binding site [nucleotide binding]; DNA binding site
502801006642	FadR C-terminal domain; Region: FadR_C; pfam07840
502801006643	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
502801006644	SpoVR family protein; Provisional; Region: PRK11767
502801006645	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
502801006646	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
502801006647	hydroxyglutarate oxidase; Provisional; Region: PRK11728
502801006648	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801006649	putative substrate translocation pore; other site
502801006650	Major Facilitator Superfamily; Region: MFS_1; pfam07690
502801006651	Pirin-related protein [General function prediction only]; Region: COG1741
502801006652	Pirin; Region: Pirin; pfam02678
502801006653	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
502801006654	LysR family transcriptional regulator; Provisional; Region: PRK14997
502801006655	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801006656	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473
502801006657	putative effector binding pocket; other site
502801006658	putative dimerization interface [polypeptide binding]; other site
502801006659	EamA-like transporter family; Region: EamA; pfam00892
502801006660	hypothetical protein; Provisional; Region: PRK05325
502801006661	PrkA family serine protein kinase; Provisional; Region: PRK15455
502801006662	AAA ATPase domain; Region: AAA_16; pfam13191
502801006663	Walker A motif; other site
502801006664	ATP binding site [chemical binding]; other site
502801006665	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
502801006666	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
502801006667	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
502801006668	active site
502801006669	phosphate binding residues; other site
502801006670	catalytic residues [active]
502801006671	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
502801006672	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
502801006673	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
502801006674	methionine sulfoxide reductase B; Provisional; Region: PRK00222
502801006675	SelR domain; Region: SelR; pfam01641
502801006676	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
502801006677	Isochorismatase family; Region: Isochorismatase; pfam00857
502801006678	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
502801006679	catalytic triad [active]
502801006680	metal binding site [ion binding]; metal-binding site
502801006681	conserved cis-peptide bond; other site
502801006682	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
502801006683	active site
502801006684	homodimer interface [polypeptide binding]; other site
502801006685	protease 4; Provisional; Region: PRK10949
502801006686	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
502801006687	tandem repeat interface [polypeptide binding]; other site
502801006688	oligomer interface [polypeptide binding]; other site
502801006689	active site residues [active]
502801006690	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
502801006691	tandem repeat interface [polypeptide binding]; other site
502801006692	oligomer interface [polypeptide binding]; other site
502801006693	active site residues [active]
502801006694	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
502801006695	putative FMN binding site [chemical binding]; other site
502801006696	selenophosphate synthetase; Provisional; Region: PRK00943
502801006697	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
502801006698	dimerization interface [polypeptide binding]; other site
502801006699	putative ATP binding site [chemical binding]; other site
502801006700	DNA topoisomerase III; Provisional; Region: PRK07726
502801006701	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
502801006702	active site
502801006703	putative interdomain interaction site [polypeptide binding]; other site
502801006704	putative metal-binding site [ion binding]; other site
502801006705	putative nucleotide binding site [chemical binding]; other site
502801006706	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
502801006707	domain I; other site
502801006708	DNA binding groove [nucleotide binding]
502801006709	phosphate binding site [ion binding]; other site
502801006710	domain II; other site
502801006711	domain III; other site
502801006712	nucleotide binding site [chemical binding]; other site
502801006713	catalytic site [active]
502801006714	domain IV; other site
502801006715	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
502801006716	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
502801006717	active site
502801006718	8-oxo-dGMP binding site [chemical binding]; other site
502801006719	nudix motif; other site
502801006720	metal binding site [ion binding]; metal-binding site
502801006721	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
502801006722	putative catalytic site [active]
502801006723	putative phosphate binding site [ion binding]; other site
502801006724	active site
502801006725	metal binding site A [ion binding]; metal-binding site
502801006726	DNA binding site [nucleotide binding]
502801006727	putative AP binding site [nucleotide binding]; other site
502801006728	putative metal binding site B [ion binding]; other site
502801006729	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801006730	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801006731	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
502801006732	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
502801006733	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
502801006734	putative active site [active]
502801006735	putative substrate binding site [chemical binding]; other site
502801006736	putative cosubstrate binding site; other site
502801006737	catalytic site [active]
502801006738	SEC-C motif; Region: SEC-C; pfam02810
502801006739	hypothetical protein; Provisional; Region: PRK04233
502801006740	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801006741	active site
502801006742	response regulator of RpoS; Provisional; Region: PRK10693
502801006743	phosphorylation site [posttranslational modification]
502801006744	intermolecular recognition site; other site
502801006745	dimerization interface [polypeptide binding]; other site
502801006746	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
502801006747	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
502801006748	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
502801006749	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
502801006750	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
502801006751	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
502801006752	thymidine kinase; Provisional; Region: PRK04296
502801006753	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
502801006754	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
502801006755	putative catalytic cysteine [active]
502801006756	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
502801006757	putative active site [active]
502801006758	metal binding site [ion binding]; metal-binding site
502801006759	hypothetical protein; Provisional; Region: PRK11111
502801006760	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
502801006761	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
502801006762	peptide binding site [polypeptide binding]; other site
502801006763	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
502801006764	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801006765	dimer interface [polypeptide binding]; other site
502801006766	conserved gate region; other site
502801006767	putative PBP binding loops; other site
502801006768	ABC-ATPase subunit interface; other site
502801006769	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
502801006770	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
502801006771	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801006772	dimer interface [polypeptide binding]; other site
502801006773	conserved gate region; other site
502801006774	ABC-ATPase subunit interface; other site
502801006775	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
502801006776	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801006777	Walker A/P-loop; other site
502801006778	ATP binding site [chemical binding]; other site
502801006779	Q-loop/lid; other site
502801006780	ABC transporter signature motif; other site
502801006781	Walker B; other site
502801006782	D-loop; other site
502801006783	H-loop/switch region; other site
502801006784	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
502801006785	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
502801006786	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801006787	Walker A/P-loop; other site
502801006788	ATP binding site [chemical binding]; other site
502801006789	Q-loop/lid; other site
502801006790	ABC transporter signature motif; other site
502801006791	Walker B; other site
502801006792	D-loop; other site
502801006793	H-loop/switch region; other site
502801006794	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
502801006795	dsDNA-mimic protein; Reviewed; Region: PRK05094
502801006796	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
502801006797	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
502801006798	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
502801006799	putative active site [active]
502801006800	catalytic site [active]
502801006801	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
502801006802	putative active site [active]
502801006803	catalytic site [active]
502801006804	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801006805	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
502801006806	Transcription factor zinc-finger; Region: zf-TFIIB; cl01565
502801006807	YciI-like protein; Reviewed; Region: PRK11370
502801006808	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
502801006809	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
502801006810	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
502801006811	intracellular septation protein A; Reviewed; Region: PRK00259
502801006812	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
502801006813	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
502801006814	Sulfate transporter family; Region: Sulfate_transp; pfam00916
502801006815	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
502801006816	hypothetical protein; Provisional; Region: PRK02868
502801006817	outer membrane protein W; Provisional; Region: PRK10959
502801006818	Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823
502801006819	BON domain; Region: BON; pfam04972
502801006820	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
502801006821	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
502801006822	substrate binding site [chemical binding]; other site
502801006823	active site
502801006824	catalytic residues [active]
502801006825	heterodimer interface [polypeptide binding]; other site
502801006826	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
502801006827	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
502801006828	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801006829	catalytic residue [active]
502801006830	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
502801006831	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
502801006832	active site
502801006833	ribulose/triose binding site [chemical binding]; other site
502801006834	phosphate binding site [ion binding]; other site
502801006835	substrate (anthranilate) binding pocket [chemical binding]; other site
502801006836	product (indole) binding pocket [chemical binding]; other site
502801006837	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
502801006838	active site
502801006839	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
502801006840	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
502801006841	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
502801006842	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
502801006843	Glutamine amidotransferase class-I; Region: GATase; pfam00117
502801006844	glutamine binding [chemical binding]; other site
502801006845	catalytic triad [active]
502801006846	anthranilate synthase component I; Provisional; Region: PRK13564
502801006847	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
502801006848	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
502801006849	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
502801006850	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
502801006851	active site
502801006852	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
502801006853	hypothetical protein; Provisional; Region: PRK11630
502801006854	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
502801006855	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
502801006856	RNA binding surface [nucleotide binding]; other site
502801006857	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
502801006858	probable active site [active]
502801006859	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
502801006860	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
502801006861	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
502801006862	homodimer interface [polypeptide binding]; other site
502801006863	Walker A motif; other site
502801006864	ATP binding site [chemical binding]; other site
502801006865	hydroxycobalamin binding site [chemical binding]; other site
502801006866	Walker B motif; other site
502801006867	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
502801006868	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801006869	NAD(P) binding site [chemical binding]; other site
502801006870	active site
502801006871	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
502801006872	putative inner membrane peptidase; Provisional; Region: PRK11778
502801006873	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
502801006874	tandem repeat interface [polypeptide binding]; other site
502801006875	oligomer interface [polypeptide binding]; other site
502801006876	active site residues [active]
502801006877	hypothetical protein; Provisional; Region: PRK11037
502801006878	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
502801006879	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
502801006880	active site
502801006881	interdomain interaction site; other site
502801006882	putative metal-binding site [ion binding]; other site
502801006883	nucleotide binding site [chemical binding]; other site
502801006884	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
502801006885	domain I; other site
502801006886	DNA binding groove [nucleotide binding]
502801006887	phosphate binding site [ion binding]; other site
502801006888	domain II; other site
502801006889	domain III; other site
502801006890	nucleotide binding site [chemical binding]; other site
502801006891	catalytic site [active]
502801006892	domain IV; other site
502801006893	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
502801006894	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
502801006895	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
502801006896	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
502801006897	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
502801006898	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801006899	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
502801006900	substrate binding site [chemical binding]; other site
502801006901	putative dimerization interface [polypeptide binding]; other site
502801006902	aconitate hydratase; Validated; Region: PRK09277
502801006903	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
502801006904	substrate binding site [chemical binding]; other site
502801006905	ligand binding site [chemical binding]; other site
502801006906	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
502801006907	substrate binding site [chemical binding]; other site
502801006908	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
502801006909	dimerization interface [polypeptide binding]; other site
502801006910	active site
502801006911	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
502801006912	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
502801006913	active site
502801006914	Predicted membrane protein [Function unknown]; Region: COG3771
502801006915	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
502801006916	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
502801006917	TPR motif; other site
502801006918	binding surface
502801006919	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
502801006920	binding surface
502801006921	TPR motif; other site
502801006922	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
502801006923	active site
502801006924	dimer interface [polypeptide binding]; other site
502801006925	translation initiation factor Sui1; Validated; Region: PRK06824
502801006926	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
502801006927	putative rRNA binding site [nucleotide binding]; other site
502801006928	lipoprotein; Provisional; Region: PRK10540
502801006929	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
502801006930	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
502801006931	intersubunit interface [polypeptide binding]; other site
502801006932	active site
502801006933	Zn2+ binding site [ion binding]; other site
502801006934	Uncharacterized conserved protein [Function unknown]; Region: COG5460
502801006935	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
502801006936	active site
502801006937	intersubunit interactions; other site
502801006938	catalytic residue [active]
502801006939	Uncharacterized small protein [Function unknown]; Region: COG2879
502801006940	carbon starvation protein A; Provisional; Region: PRK15015
502801006941	Carbon starvation protein CstA; Region: CstA; pfam02554
502801006942	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
502801006943	exoribonuclease II; Provisional; Region: PRK05054
502801006944	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
502801006945	RNB domain; Region: RNB; pfam00773
502801006946	S1 RNA binding domain; Region: S1; pfam00575
502801006947	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
502801006948	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801006949	putative substrate translocation pore; other site
502801006950	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
502801006951	Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238
502801006952	putative NAD(P) binding site [chemical binding]; other site
502801006953	active site
502801006954	putative substrate binding site [chemical binding]; other site
502801006955	endonuclease III; Provisional; Region: PRK10702
502801006956	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
502801006957	minor groove reading motif; other site
502801006958	helix-hairpin-helix signature motif; other site
502801006959	substrate binding pocket [chemical binding]; other site
502801006960	active site
502801006961	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
502801006962	electron transport complex RsxE subunit; Provisional; Region: PRK12405
502801006963	electron transport complex protein RnfG; Validated; Region: PRK01908
502801006964	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
502801006965	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
502801006966	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801006967	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
502801006968	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
502801006969	SLBB domain; Region: SLBB; pfam10531
502801006970	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
502801006971	electron transport complex protein RnfB; Provisional; Region: PRK05113
502801006972	Putative Fe-S cluster; Region: FeS; pfam04060
502801006973	4Fe-4S binding domain; Region: Fer4; pfam00037
502801006974	electron transport complex protein RsxA; Provisional; Region: PRK05151
502801006975	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
502801006976	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cd02259
502801006977	putative active site [active]
502801006978	type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846
502801006979	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801006980	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801006981	Walker A/P-loop; other site
502801006982	ATP binding site [chemical binding]; other site
502801006983	Q-loop/lid; other site
502801006984	ABC transporter signature motif; other site
502801006985	Walker B; other site
502801006986	D-loop; other site
502801006987	H-loop/switch region; other site
502801006988	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
502801006989	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801006990	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801006991	A sub-family of peptidase C39 which contains Cyclolysin and Hemolysin processing peptidases.  Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine...; Region: Peptidase_C39_likeA; cd02417
502801006992	type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846
502801006993	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801006994	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801006995	Walker A/P-loop; other site
502801006996	ATP binding site [chemical binding]; other site
502801006997	Q-loop/lid; other site
502801006998	ABC transporter signature motif; other site
502801006999	Walker B; other site
502801007000	D-loop; other site
502801007001	H-loop/switch region; other site
502801007002	L-arabinose isomerase; Provisional; Region: PRK02929
502801007003	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
502801007004	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
502801007005	trimer interface [polypeptide binding]; other site
502801007006	putative substrate binding site [chemical binding]; other site
502801007007	putative metal binding site [ion binding]; other site
502801007008	ribulokinase; Provisional; Region: PRK04123
502801007009	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
502801007010	N- and C-terminal domain interface [polypeptide binding]; other site
502801007011	active site
502801007012	MgATP binding site [chemical binding]; other site
502801007013	catalytic site [active]
502801007014	metal binding site [ion binding]; metal-binding site
502801007015	carbohydrate binding site [chemical binding]; other site
502801007016	homodimer interface [polypeptide binding]; other site
502801007017	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
502801007018	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
502801007019	ligand binding site [chemical binding]; other site
502801007020	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
502801007021	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801007022	Walker A/P-loop; other site
502801007023	ATP binding site [chemical binding]; other site
502801007024	Q-loop/lid; other site
502801007025	ABC transporter signature motif; other site
502801007026	Walker B; other site
502801007027	D-loop; other site
502801007028	H-loop/switch region; other site
502801007029	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801007030	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801007031	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801007032	TM-ABC transporter signature motif; other site
502801007033	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
502801007034	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
502801007035	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801007036	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801007037	putative oxidoreductase; Provisional; Region: PRK11579
502801007038	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
502801007039	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
502801007040	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
502801007041	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
502801007042	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
502801007043	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
502801007044	active site
502801007045	purine riboside binding site [chemical binding]; other site
502801007046	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; cl17885
502801007047	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
502801007048	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801007049	DNA-binding site [nucleotide binding]; DNA binding site
502801007050	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
502801007051	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
502801007052	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
502801007053	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
502801007054	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
502801007055	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
502801007056	fumarate hydratase; Reviewed; Region: fumC; PRK00485
502801007057	Class II fumarases; Region: Fumarase_classII; cd01362
502801007058	active site
502801007059	tetramer interface [polypeptide binding]; other site
502801007060	DNA replication terminus site-binding protein; Region: rep_term_tus; TIGR02648
502801007061	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
502801007062	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801007063	putative substrate translocation pore; other site
502801007064	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
502801007065	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801007066	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
502801007067	dimerization interface [polypeptide binding]; other site
502801007068	substrate binding pocket [chemical binding]; other site
502801007069	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
502801007070	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
502801007071	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
502801007072	nucleotide binding site [chemical binding]; other site
502801007073	putative dithiobiotin synthetase; Provisional; Region: PRK12374
502801007074	AAA domain; Region: AAA_26; pfam13500
502801007075	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
502801007076	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
502801007077	Cl- selectivity filter; other site
502801007078	Cl- binding residues [ion binding]; other site
502801007079	pore gating glutamate residue; other site
502801007080	dimer interface [polypeptide binding]; other site
502801007081	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
502801007082	hypothetical protein; Provisional; Region: PRK13659
502801007083	malonic semialdehyde reductase; Provisional; Region: PRK10538
502801007084	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801007085	NAD(P) binding site [chemical binding]; other site
502801007086	active site
502801007087	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801007088	Walker A motif; other site
502801007089	ATP binding site [chemical binding]; other site
502801007090	Walker B motif; other site
502801007091	arginine finger; other site
502801007092	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
502801007093	hypothetical protein; Provisional; Region: PRK13659
502801007094	malonic semialdehyde reductase; Provisional; Region: PRK10538
502801007095	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801007096	NAD(P) binding site [chemical binding]; other site
502801007097	active site
502801007098	Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284
502801007099	GAF domain; Region: GAF; pfam01590
502801007100	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801007101	Walker A motif; other site
502801007102	ATP binding site [chemical binding]; other site
502801007103	Walker B motif; other site
502801007104	arginine finger; other site
502801007105	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
502801007106	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
502801007107	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
502801007108	NAD(P) binding site [chemical binding]; other site
502801007109	catalytic residues [active]
502801007110	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
502801007111	EamA-like transporter family; Region: EamA; pfam00892
502801007112	EamA-like transporter family; Region: EamA; pfam00892
502801007113	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
502801007114	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801007115	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801007116	homodimer interface [polypeptide binding]; other site
502801007117	catalytic residue [active]
502801007118	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
502801007119	Transcriptional regulators [Transcription]; Region: PurR; COG1609
502801007120	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801007121	DNA binding site [nucleotide binding]
502801007122	domain linker motif; other site
502801007123	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
502801007124	dimerization interface (closed form) [polypeptide binding]; other site
502801007125	ligand binding site [chemical binding]; other site
502801007126	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
502801007127	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
502801007128	ligand binding site [chemical binding]; other site
502801007129	dimerization interface [polypeptide binding]; other site
502801007130	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801007131	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801007132	TM-ABC transporter signature motif; other site
502801007133	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801007134	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801007135	Walker A/P-loop; other site
502801007136	ATP binding site [chemical binding]; other site
502801007137	Q-loop/lid; other site
502801007138	ABC transporter signature motif; other site
502801007139	Walker B; other site
502801007140	D-loop; other site
502801007141	H-loop/switch region; other site
502801007142	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801007143	Predicted periplasmic lipoprotein (DUF2291); Region: DUF2291; pfam10054
502801007144	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
502801007145	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
502801007146	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
502801007147	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801007148	dimer interface [polypeptide binding]; other site
502801007149	conserved gate region; other site
502801007150	putative PBP binding loops; other site
502801007151	ABC-ATPase subunit interface; other site
502801007152	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
502801007153	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
502801007154	Walker A/P-loop; other site
502801007155	ATP binding site [chemical binding]; other site
502801007156	Q-loop/lid; other site
502801007157	ABC transporter signature motif; other site
502801007158	Walker B; other site
502801007159	D-loop; other site
502801007160	H-loop/switch region; other site
502801007161	AMP nucleosidase; Provisional; Region: PRK08292
502801007162	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
502801007163	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
502801007164	ribonuclease E; Reviewed; Region: rne; PRK10811
502801007165	Virulence factor SrfB; Region: SrfB; pfam07520
502801007166	Uncharacterized protein conserved in bacteria, putative virulence factor [Function unknown]; Region: SrfC; COG4458
502801007167	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
502801007168	G1 box; other site
502801007169	GTP/Mg2+ binding site [chemical binding]; other site
502801007170	G2 box; other site
502801007171	Switch I region; other site
502801007172	G3 box; other site
502801007173	Switch II region; other site
502801007174	G4 box; other site
502801007175	Protein of unknown function (DUF1460); Region: DUF1460; pfam07313
502801007176	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
502801007177	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
502801007178	PYR/PP interface [polypeptide binding]; other site
502801007179	dimer interface [polypeptide binding]; other site
502801007180	TPP binding site [chemical binding]; other site
502801007181	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
502801007182	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
502801007183	TPP-binding site [chemical binding]; other site
502801007184	dimer interface [polypeptide binding]; other site
502801007185	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
502801007186	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
502801007187	putative valine binding site [chemical binding]; other site
502801007188	dimer interface [polypeptide binding]; other site
502801007189	dUMP phosphatase; Provisional; Region: PRK09449
502801007190	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801007191	motif II; other site
502801007192	Domain of unknown function (DUF4016); Region: DUF4016; pfam13208
502801007193	tellurite resistance protein terB; Region: terB; cd07176
502801007194	putative metal binding site [ion binding]; other site
502801007195	alkaline phosphatase; Provisional; Region: PRK10518
502801007196	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
502801007197	dimer interface [polypeptide binding]; other site
502801007198	active site
502801007199	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
502801007200	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
502801007201	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
502801007202	DNA binding site [nucleotide binding]
502801007203	active site
502801007204	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
502801007205	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
502801007206	ligand binding site [chemical binding]; other site
502801007207	flexible hinge region; other site
502801007208	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
502801007209	putative switch regulator; other site
502801007210	non-specific DNA interactions [nucleotide binding]; other site
502801007211	DNA binding site [nucleotide binding]
502801007212	sequence specific DNA binding site [nucleotide binding]; other site
502801007213	putative cAMP binding site [chemical binding]; other site
502801007214	universal stress protein UspE; Provisional; Region: PRK11175
502801007215	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
502801007216	Ligand Binding Site [chemical binding]; other site
502801007217	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
502801007218	Ligand Binding Site [chemical binding]; other site
502801007219	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
502801007220	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
502801007221	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
502801007222	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
502801007223	ligand binding site [chemical binding]; other site
502801007224	homodimer interface [polypeptide binding]; other site
502801007225	NAD(P) binding site [chemical binding]; other site
502801007226	trimer interface B [polypeptide binding]; other site
502801007227	trimer interface A [polypeptide binding]; other site
502801007228	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
502801007229	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
502801007230	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
502801007231	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
502801007232	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
502801007233	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
502801007234	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801007235	active site
502801007236	phosphorylation site [posttranslational modification]
502801007237	intermolecular recognition site; other site
502801007238	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801007239	DNA binding site [nucleotide binding]
502801007240	sensor protein RstB; Provisional; Region: PRK10604
502801007241	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801007242	dimerization interface [polypeptide binding]; other site
502801007243	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801007244	dimer interface [polypeptide binding]; other site
502801007245	phosphorylation site [posttranslational modification]
502801007246	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801007247	ATP binding site [chemical binding]; other site
502801007248	Mg2+ binding site [ion binding]; other site
502801007249	G-X-G motif; other site
502801007250	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
502801007251	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
502801007252	active site
502801007253	Zn binding site [ion binding]; other site
502801007254	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
502801007255	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
502801007256	Anthrax toxin LF subunit; Region: Anthrax_toxA; pfam03497
502801007257	hypothetical protein; Provisional; Region: PRK03757
502801007258	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
502801007259	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
502801007260	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
502801007261	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
502801007262	non-specific DNA binding site [nucleotide binding]; other site
502801007263	salt bridge; other site
502801007264	sequence-specific DNA binding site [nucleotide binding]; other site
502801007265	Phage-related protein [Function unknown]; Region: COG4679
502801007266	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
502801007267	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
502801007268	ATP binding site [chemical binding]; other site
502801007269	putative Mg++ binding site [ion binding]; other site
502801007270	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801007271	nucleotide binding region [chemical binding]; other site
502801007272	ATP-binding site [chemical binding]; other site
502801007273	Helicase associated domain (HA2); Region: HA2; pfam04408
502801007274	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
502801007275	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
502801007276	azoreductase; Reviewed; Region: PRK00170
502801007277	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
502801007278	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
502801007279	MarR family; Region: MarR_2; pfam12802
502801007280	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
502801007281	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
502801007282	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
502801007283	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
502801007284	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
502801007285	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
502801007286	hypothetical protein; Provisional; Region: PRK10695
502801007287	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
502801007288	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
502801007289	putative ligand binding site [chemical binding]; other site
502801007290	putative NAD binding site [chemical binding]; other site
502801007291	catalytic site [active]
502801007292	heat-inducible protein; Provisional; Region: PRK10449
502801007293	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
502801007294	Domain of unknown function (DUF333); Region: DUF333; pfam03891
502801007295	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
502801007296	MgtC family; Region: MgtC; pfam02308
502801007297	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
502801007298	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
502801007299	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
502801007300	dimer interface [polypeptide binding]; other site
502801007301	PYR/PP interface [polypeptide binding]; other site
502801007302	TPP binding site [chemical binding]; other site
502801007303	substrate binding site [chemical binding]; other site
502801007304	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
502801007305	Domain of unknown function; Region: EKR; pfam10371
502801007306	4Fe-4S binding domain; Region: Fer4_6; pfam12837
502801007307	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
502801007308	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
502801007309	TPP-binding site [chemical binding]; other site
502801007310	dimer interface [polypeptide binding]; other site
502801007311	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
502801007312	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
502801007313	Ligand Binding Site [chemical binding]; other site
502801007314	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
502801007315	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
502801007316	substrate binding pocket [chemical binding]; other site
502801007317	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
502801007318	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
502801007319	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
502801007320	DNA binding residues [nucleotide binding]
502801007321	dimer interface [polypeptide binding]; other site
502801007322	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
502801007323	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
502801007324	Cl binding site [ion binding]; other site
502801007325	oligomer interface [polypeptide binding]; other site
502801007326	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
502801007327	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
502801007328	peptide binding site [polypeptide binding]; other site
502801007329	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
502801007330	murein peptide amidase A; Provisional; Region: PRK10602
502801007331	active site
502801007332	Zn binding site [ion binding]; other site
502801007333	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
502801007334	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
502801007335	active site
502801007336	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
502801007337	dimer interface [polypeptide binding]; other site
502801007338	catalytic triad [active]
502801007339	peroxidatic and resolving cysteines [active]
502801007340	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
502801007341	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
502801007342	PAS domain; Region: PAS; smart00091
502801007343	putative active site [active]
502801007344	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801007345	Walker A motif; other site
502801007346	ATP binding site [chemical binding]; other site
502801007347	Walker B motif; other site
502801007348	arginine finger; other site
502801007349	Uncharacterized conserved protein [Function unknown]; Region: COG5642
502801007350	putative toxin-antitoxin system antitoxin component, TIGR02293 family; Region: TAS_TIGR02293
502801007351	Uncharacterized conserved protein [Function unknown]; Region: COG5654
502801007352	hypothetical protein; Provisional; Region: PRK05415
502801007353	Domain of unknown function (DUF697); Region: DUF697; cl12064
502801007354	Predicted ATPase [General function prediction only]; Region: COG3106
502801007355	Phage shock protein PspD (Phageshock_PspD); Region: Phageshock_PspD; pfam09584
502801007356	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
502801007357	phage shock protein C; Region: phageshock_pspC; TIGR02978
502801007358	phage shock protein B; Provisional; Region: pspB; PRK09458
502801007359	phage shock protein PspA; Provisional; Region: PRK10698
502801007360	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
502801007361	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801007362	Walker A motif; other site
502801007363	ATP binding site [chemical binding]; other site
502801007364	Walker B motif; other site
502801007365	arginine finger; other site
502801007366	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
502801007367	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
502801007368	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
502801007369	peptide binding site [polypeptide binding]; other site
502801007370	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
502801007371	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801007372	dimer interface [polypeptide binding]; other site
502801007373	conserved gate region; other site
502801007374	putative PBP binding loops; other site
502801007375	ABC-ATPase subunit interface; other site
502801007376	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
502801007377	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801007378	putative PBP binding loops; other site
502801007379	dimer interface [polypeptide binding]; other site
502801007380	ABC-ATPase subunit interface; other site
502801007381	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
502801007382	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801007383	Walker A/P-loop; other site
502801007384	ATP binding site [chemical binding]; other site
502801007385	Q-loop/lid; other site
502801007386	ABC transporter signature motif; other site
502801007387	Walker B; other site
502801007388	D-loop; other site
502801007389	H-loop/switch region; other site
502801007390	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
502801007391	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
502801007392	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801007393	Walker A/P-loop; other site
502801007394	ATP binding site [chemical binding]; other site
502801007395	Q-loop/lid; other site
502801007396	ABC transporter signature motif; other site
502801007397	Walker B; other site
502801007398	D-loop; other site
502801007399	H-loop/switch region; other site
502801007400	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
502801007401	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
502801007402	Uncharacterized conserved protein [Function unknown]; Region: COG2128
502801007403	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
502801007404	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
502801007405	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801007406	putative substrate translocation pore; other site
502801007407	POT family; Region: PTR2; pfam00854
502801007408	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
502801007409	hypothetical protein; Provisional; Region: PRK10515
502801007410	glutathionine S-transferase; Provisional; Region: PRK10542
502801007411	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
502801007412	C-terminal domain interface [polypeptide binding]; other site
502801007413	GSH binding site (G-site) [chemical binding]; other site
502801007414	dimer interface [polypeptide binding]; other site
502801007415	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
502801007416	dimer interface [polypeptide binding]; other site
502801007417	N-terminal domain interface [polypeptide binding]; other site
502801007418	substrate binding pocket (H-site) [chemical binding]; other site
502801007419	pyridoxamine kinase; Validated; Region: PRK05756
502801007420	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
502801007421	dimer interface [polypeptide binding]; other site
502801007422	pyridoxal binding site [chemical binding]; other site
502801007423	ATP binding site [chemical binding]; other site
502801007424	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
502801007425	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
502801007426	active site
502801007427	HIGH motif; other site
502801007428	dimer interface [polypeptide binding]; other site
502801007429	KMSKS motif; other site
502801007430	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
502801007431	RNA binding surface [nucleotide binding]; other site
502801007432	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
502801007433	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
502801007434	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
502801007435	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
502801007436	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
502801007437	active site
502801007438	catalytic tetrad [active]
502801007439	Predicted Fe-S protein [General function prediction only]; Region: COG3313
502801007440	putative metal dependent hydrolase; Provisional; Region: PRK11598
502801007441	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
502801007442	Sulfatase; Region: Sulfatase; pfam00884
502801007443	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
502801007444	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
502801007445	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
502801007446	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
502801007447	FMN binding site [chemical binding]; other site
502801007448	active site
502801007449	substrate binding site [chemical binding]; other site
502801007450	catalytic residue [active]
502801007451	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
502801007452	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
502801007453	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
502801007454	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
502801007455	dimer interface [polypeptide binding]; other site
502801007456	active site
502801007457	metal binding site [ion binding]; metal-binding site
502801007458	glutathione binding site [chemical binding]; other site
502801007459	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
502801007460	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
502801007461	dimer interface [polypeptide binding]; other site
502801007462	catalytic site [active]
502801007463	putative active site [active]
502801007464	putative substrate binding site [chemical binding]; other site
502801007465	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
502801007466	putative GSH binding site [chemical binding]; other site
502801007467	catalytic residues [active]
502801007468	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
502801007469	NlpC/P60 family; Region: NLPC_P60; pfam00877
502801007470	superoxide dismutase; Provisional; Region: PRK10543
502801007471	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
502801007472	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
502801007473	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
502801007474	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801007475	DNA binding site [nucleotide binding]
502801007476	domain linker motif; other site
502801007477	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
502801007478	dimerization interface [polypeptide binding]; other site
502801007479	ligand binding site [chemical binding]; other site
502801007480	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
502801007481	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801007482	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
502801007483	dimerization interface [polypeptide binding]; other site
502801007484	putative transporter; Provisional; Region: PRK11043
502801007485	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801007486	putative substrate translocation pore; other site
502801007487	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
502801007488	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801007489	S-adenosylmethionine binding site [chemical binding]; other site
502801007490	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
502801007491	Lumazine binding domain; Region: Lum_binding; pfam00677
502801007492	Lumazine binding domain; Region: Lum_binding; pfam00677
502801007493	multidrug efflux protein; Reviewed; Region: PRK01766
502801007494	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
502801007495	cation binding site [ion binding]; other site
502801007496	pyruvate kinase; Provisional; Region: PRK09206
502801007497	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
502801007498	domain interfaces; other site
502801007499	active site
502801007500	murein lipoprotein; Provisional; Region: PRK15396
502801007501	L,D-transpeptidase; Provisional; Region: PRK10190
502801007502	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
502801007503	cysteine desufuration protein SufE; Provisional; Region: PRK09296
502801007504	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
502801007505	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
502801007506	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801007507	catalytic residue [active]
502801007508	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
502801007509	FeS assembly protein SufD; Region: sufD; TIGR01981
502801007510	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
502801007511	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
502801007512	Walker A/P-loop; other site
502801007513	ATP binding site [chemical binding]; other site
502801007514	Q-loop/lid; other site
502801007515	ABC transporter signature motif; other site
502801007516	Walker B; other site
502801007517	D-loop; other site
502801007518	H-loop/switch region; other site
502801007519	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
502801007520	putative ABC transporter; Region: ycf24; CHL00085
502801007521	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
502801007522	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
502801007523	CoenzymeA binding site [chemical binding]; other site
502801007524	subunit interaction site [polypeptide binding]; other site
502801007525	PHB binding site; other site
502801007526	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
502801007527	FAD binding domain; Region: FAD_binding_4; pfam01565
502801007528	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
502801007529	putative inner membrane protein; Provisional; Region: PRK10983
502801007530	Domain of unknown function DUF20; Region: UPF0118; pfam01594
502801007531	phosphoenolpyruvate synthase; Validated; Region: PRK06464
502801007532	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
502801007533	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
502801007534	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
502801007535	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1806
502801007536	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
502801007537	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
502801007538	hypothetical protein; Validated; Region: PRK00029
502801007539	Uncharacterized conserved protein [Function unknown]; Region: COG0397
502801007540	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
502801007541	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
502801007542	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
502801007543	NlpC/P60 family; Region: NLPC_P60; pfam00877
502801007544	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
502801007545	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
502801007546	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
502801007547	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
502801007548	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
502801007549	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
502801007550	putative active site [active]
502801007551	putative catalytic site [active]
502801007552	putative Zn binding site [ion binding]; other site
502801007553	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
502801007554	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
502801007555	active site
502801007556	substrate binding site [chemical binding]; other site
502801007557	cosubstrate binding site; other site
502801007558	catalytic site [active]
502801007559	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
502801007560	active site
502801007561	hexamer interface [polypeptide binding]; other site
502801007562	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
502801007563	NAD binding site [chemical binding]; other site
502801007564	substrate binding site [chemical binding]; other site
502801007565	active site
502801007566	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
502801007567	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
502801007568	Ligand binding site; other site
502801007569	Putative Catalytic site; other site
502801007570	DXD motif; other site
502801007571	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
502801007572	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
502801007573	inhibitor-cofactor binding pocket; inhibition site
502801007574	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801007575	catalytic residue [active]
502801007576	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
502801007577	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
502801007578	Walker A/P-loop; other site
502801007579	ATP binding site [chemical binding]; other site
502801007580	Q-loop/lid; other site
502801007581	ABC transporter signature motif; other site
502801007582	Walker B; other site
502801007583	D-loop; other site
502801007584	H-loop/switch region; other site
502801007585	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
502801007586	catalytic residues [active]
502801007587	dimer interface [polypeptide binding]; other site
502801007588	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
502801007589	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801007590	ABC-ATPase subunit  interface; other site
502801007591	dimer interface [polypeptide binding]; other site
502801007592	putative PBP binding regions; other site
502801007593	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
502801007594	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
502801007595	IHF dimer interface [polypeptide binding]; other site
502801007596	IHF - DNA interface [nucleotide binding]; other site
502801007597	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
502801007598	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
502801007599	putative tRNA-binding site [nucleotide binding]; other site
502801007600	B3/4 domain; Region: B3_4; pfam03483
502801007601	tRNA synthetase B5 domain; Region: B5; smart00874
502801007602	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
502801007603	dimer interface [polypeptide binding]; other site
502801007604	motif 1; other site
502801007605	motif 3; other site
502801007606	motif 2; other site
502801007607	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
502801007608	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
502801007609	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
502801007610	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
502801007611	dimer interface [polypeptide binding]; other site
502801007612	motif 1; other site
502801007613	active site
502801007614	motif 2; other site
502801007615	motif 3; other site
502801007616	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
502801007617	23S rRNA binding site [nucleotide binding]; other site
502801007618	L21 binding site [polypeptide binding]; other site
502801007619	L13 binding site [polypeptide binding]; other site
502801007620	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
502801007621	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
502801007622	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
502801007623	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
502801007624	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
502801007625	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
502801007626	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
502801007627	active site
502801007628	dimer interface [polypeptide binding]; other site
502801007629	motif 1; other site
502801007630	motif 2; other site
502801007631	motif 3; other site
502801007632	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
502801007633	anticodon binding site; other site
502801007634	KTSC domain; Region: KTSC; pfam13619
502801007635	inner membrane protein; Provisional; Region: PRK10995
502801007636	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
502801007637	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
502801007638	N-acetyl-D-glucosamine binding site [chemical binding]; other site
502801007639	catalytic residue [active]
502801007640	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
502801007641	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
502801007642	metal binding site [ion binding]; metal-binding site
502801007643	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
502801007644	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
502801007645	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
502801007646	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801007647	ABC-ATPase subunit  interface; other site
502801007648	dimer interface [polypeptide binding]; other site
502801007649	putative PBP binding regions; other site
502801007650	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
502801007651	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801007652	ABC-ATPase subunit  interface; other site
502801007653	dimer interface [polypeptide binding]; other site
502801007654	putative PBP binding regions; other site
502801007655	Phosphotransferase enzyme family; Region: APH; pfam01636
502801007656	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
502801007657	active site
502801007658	ATP binding site [chemical binding]; other site
502801007659	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
502801007660	YniB-like protein; Region: YniB; pfam14002
502801007661	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
502801007662	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801007663	motif II; other site
502801007664	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
502801007665	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
502801007666	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
502801007667	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
502801007668	NADP binding site [chemical binding]; other site
502801007669	homodimer interface [polypeptide binding]; other site
502801007670	active site
502801007671	Periplasmic pectate lyase; Region: Pectate_lyase_2; pfam06917
502801007672	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801007673	dimer interface [polypeptide binding]; other site
502801007674	conserved gate region; other site
502801007675	putative PBP binding loops; other site
502801007676	ABC-ATPase subunit interface; other site
502801007677	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
502801007678	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801007679	dimer interface [polypeptide binding]; other site
502801007680	conserved gate region; other site
502801007681	putative PBP binding loops; other site
502801007682	ABC-ATPase subunit interface; other site
502801007683	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
502801007684	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801007685	Walker A/P-loop; other site
502801007686	ATP binding site [chemical binding]; other site
502801007687	Q-loop/lid; other site
502801007688	ABC transporter signature motif; other site
502801007689	Walker B; other site
502801007690	D-loop; other site
502801007691	H-loop/switch region; other site
502801007692	TOBE domain; Region: TOBE_2; pfam08402
502801007693	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
502801007694	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
502801007695	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
502801007696	inner membrane protein; Provisional; Region: PRK11648
502801007697	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
502801007698	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
502801007699	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
502801007700	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
502801007701	amidase catalytic site [active]
502801007702	Zn binding residues [ion binding]; other site
502801007703	substrate binding site [chemical binding]; other site
502801007704	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
502801007705	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
502801007706	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
502801007707	dimerization interface [polypeptide binding]; other site
502801007708	putative Zn2+ binding site [ion binding]; other site
502801007709	putative DNA binding site [nucleotide binding]; other site
502801007710	Bacterial transcriptional regulator; Region: IclR; pfam01614
502801007711	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
502801007712	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
502801007713	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801007714	Major Facilitator Superfamily; Region: MFS_1; pfam07690
502801007715	putative substrate translocation pore; other site
502801007716	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
502801007717	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801007718	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
502801007719	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
502801007720	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
502801007721	PapC N-terminal domain; Region: PapC_N; pfam13954
502801007722	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
502801007723	PapC C-terminal domain; Region: PapC_C; pfam13953
502801007724	fimbrial assembly chaperone StbE; Provisional; Region: PRK15246
502801007725	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801007726	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
502801007727	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
502801007728	heat shock protein HtpX; Provisional; Region: PRK05457
502801007729	carboxy-terminal protease; Provisional; Region: PRK11186
502801007730	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
502801007731	protein binding site [polypeptide binding]; other site
502801007732	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
502801007733	Catalytic dyad [active]
502801007734	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
502801007735	ProP expression regulator; Provisional; Region: PRK04950
502801007736	ProQ/FINO family; Region: ProQ; pfam04352
502801007737	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
502801007738	GAF domain; Region: GAF_2; pfam13185
502801007739	Uncharacterized paraquat-inducible protein A [Function unknown]; Region: PqiA; COG2995
502801007740	Paraquat-inducible protein A; Region: PqiA; pfam04403
502801007741	Paraquat-inducible protein A; Region: PqiA; pfam04403
502801007742	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
502801007743	mce related protein; Region: MCE; pfam02470
502801007744	mce related protein; Region: MCE; pfam02470
502801007745	mce related protein; Region: MCE; pfam02470
502801007746	mce related protein; Region: MCE; pfam02470
502801007747	mce related protein; Region: MCE; pfam02470
502801007748	mce related protein; Region: MCE; pfam02470
502801007749	Uncharacterized secreted protein [Function unknown]; Region: COG5430
502801007750	Uncharacterized secreted protein [Function unknown]; Region: COG5430
502801007751	Uncharacterized secreted protein [Function unknown]; Region: COG5430
502801007752	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
502801007753	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801007754	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
502801007755	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
502801007756	PapC C-terminal domain; Region: PapC_C; pfam13953
502801007757	Spore Coat Protein U domain; Region: SCPU; pfam05229
502801007758	Uncharacterized secreted protein [Function unknown]; Region: COG5430
502801007759	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
502801007760	ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to...; Region: ASCH_Ef3133_like; cd06553
502801007761	Patatin-like phospholipase; Region: Patatin; pfam01734
502801007762	nucleophile elbow; other site
502801007763	Lipase; Region: Lipase; pfam00151
502801007764	alanine racemase; Reviewed; Region: PRK13340
502801007765	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme, Alanine Racemase 2; Region: PLPDE_III_AR2; cd06826
502801007766	active site
502801007767	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
502801007768	dimer interface [polypeptide binding]; other site
502801007769	substrate binding site [chemical binding]; other site
502801007770	catalytic residues [active]
502801007771	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
502801007772	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
502801007773	trimer interface [polypeptide binding]; other site
502801007774	YadA-like C-terminal region; Region: YadA; pfam03895
502801007775	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
502801007776	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
502801007777	amidase catalytic site [active]
502801007778	Zn binding residues [ion binding]; other site
502801007779	substrate binding site [chemical binding]; other site
502801007780	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
502801007781	chemotaxis regulator CheZ; Provisional; Region: PRK11166
502801007782	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
502801007783	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801007784	active site
502801007785	phosphorylation site [posttranslational modification]
502801007786	intermolecular recognition site; other site
502801007787	dimerization interface [polypeptide binding]; other site
502801007788	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
502801007789	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801007790	active site
502801007791	phosphorylation site [posttranslational modification]
502801007792	intermolecular recognition site; other site
502801007793	dimerization interface [polypeptide binding]; other site
502801007794	CheB methylesterase; Region: CheB_methylest; pfam01339
502801007795	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
502801007796	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
502801007797	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801007798	methyl-accepting protein IV; Provisional; Region: PRK09793
502801007799	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
502801007800	dimer interface [polypeptide binding]; other site
502801007801	ligand binding site [chemical binding]; other site
502801007802	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801007803	dimerization interface [polypeptide binding]; other site
502801007804	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
502801007805	dimer interface [polypeptide binding]; other site
502801007806	putative CheW interface [polypeptide binding]; other site
502801007807	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
502801007808	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
502801007809	dimer interface [polypeptide binding]; other site
502801007810	ligand binding site [chemical binding]; other site
502801007811	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801007812	dimerization interface [polypeptide binding]; other site
502801007813	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
502801007814	dimer interface [polypeptide binding]; other site
502801007815	putative CheW interface [polypeptide binding]; other site
502801007816	hypothetical protein; Provisional; Region: PRK10215
502801007817	Predicted membrane protein [Function unknown]; Region: COG5373
502801007818	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
502801007819	putative CheA interaction surface; other site
502801007820	chemotaxis protein CheA; Provisional; Region: PRK10547
502801007821	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
502801007822	putative binding surface; other site
502801007823	active site
502801007824	CheY binding; Region: CheY-binding; pfam09078
502801007825	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
502801007826	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801007827	ATP binding site [chemical binding]; other site
502801007828	Mg2+ binding site [ion binding]; other site
502801007829	G-X-G motif; other site
502801007830	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
502801007831	flagellar motor protein MotB; Validated; Region: motB; PRK09041
502801007832	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
502801007833	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
502801007834	ligand binding site [chemical binding]; other site
502801007835	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
502801007836	flagellar motor protein MotA; Validated; Region: PRK09110
502801007837	transcriptional activator FlhC; Provisional; Region: PRK12722
502801007838	transcriptional activator FlhD; Provisional; Region: PRK02909
502801007839	magnesium-transporting ATPase; Provisional; Region: PRK15122
502801007840	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
502801007841	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
502801007842	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
502801007843	Soluble P-type ATPase [General function prediction only]; Region: COG4087
502801007844	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
502801007845	magnesium transport protein MgtC; Provisional; Region: PRK15385
502801007846	MgtC family; Region: MgtC; pfam02308
502801007847	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
502801007848	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
502801007849	dimer interface [polypeptide binding]; other site
502801007850	ligand binding site [chemical binding]; other site
502801007851	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801007852	dimerization interface [polypeptide binding]; other site
502801007853	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
502801007854	dimer interface [polypeptide binding]; other site
502801007855	putative CheW interface [polypeptide binding]; other site
502801007856	hypothetical protein; Provisional; Region: PRK10708
502801007857	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
502801007858	DNA-binding site [nucleotide binding]; DNA binding site
502801007859	RNA-binding motif; other site
502801007860	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
502801007861	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
502801007862	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
502801007863	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
502801007864	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
502801007865	putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824
502801007866	PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276
502801007867	NAD(P) binding site [chemical binding]; other site
502801007868	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
502801007869	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
502801007870	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
502801007871	putative DNA binding site [nucleotide binding]; other site
502801007872	putative Zn2+ binding site [ion binding]; other site
502801007873	AsnC family; Region: AsnC_trans_reg; pfam01037
502801007874	3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase; Region: Kdo_hydroxy; pfam11004
502801007875	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
502801007876	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
502801007877	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
502801007878	catalytic core [active]
502801007879	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
502801007880	Predicted transcriptional regulators [Transcription]; Region: COG1733
502801007881	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
502801007882	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
502801007883	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
502801007884	NADP binding site [chemical binding]; other site
502801007885	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
502801007886	PAS domain; Region: PAS_9; pfam13426
502801007887	putative active site [active]
502801007888	heme pocket [chemical binding]; other site
502801007889	HAMP domain; Region: HAMP; pfam00672
502801007890	dimerization interface [polypeptide binding]; other site
502801007891	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
502801007892	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
502801007893	dimer interface [polypeptide binding]; other site
502801007894	putative CheW interface [polypeptide binding]; other site
502801007895	Transcriptional regulators [Transcription]; Region: PurR; COG1609
502801007896	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801007897	DNA binding site [nucleotide binding]
502801007898	domain linker motif; other site
502801007899	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
502801007900	putative dimerization interface [polypeptide binding]; other site
502801007901	putative ligand binding site [chemical binding]; other site
502801007902	isocitrate dehydrogenase; Validated; Region: PRK07362
502801007903	isocitrate dehydrogenase; Reviewed; Region: PRK07006
502801007904	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
502801007905	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
502801007906	probable active site [active]
502801007907	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
502801007908	nudix motif; other site
502801007909	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
502801007910	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
502801007911	putative lysogenization regulator; Reviewed; Region: PRK00218
502801007912	adenylosuccinate lyase; Provisional; Region: PRK09285
502801007913	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
502801007914	tetramer interface [polypeptide binding]; other site
502801007915	active site
502801007916	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
502801007917	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
502801007918	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801007919	active site
502801007920	phosphorylation site [posttranslational modification]
502801007921	intermolecular recognition site; other site
502801007922	dimerization interface [polypeptide binding]; other site
502801007923	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801007924	DNA binding site [nucleotide binding]
502801007925	sensor protein PhoQ; Provisional; Region: PRK10815
502801007926	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
502801007927	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
502801007928	dimer interface [polypeptide binding]; other site
502801007929	phosphorylation site [posttranslational modification]
502801007930	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801007931	ATP binding site [chemical binding]; other site
502801007932	Mg2+ binding site [ion binding]; other site
502801007933	G-X-G motif; other site
502801007934	Uncharacterized conserved protein [Function unknown]; Region: COG2850
502801007935	Cupin-like domain; Region: Cupin_8; pfam13621
502801007936	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
502801007937	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
502801007938	metal binding site [ion binding]; metal-binding site
502801007939	dimer interface [polypeptide binding]; other site
502801007940	NAD-dependent deacetylase; Provisional; Region: PRK00481
502801007941	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
502801007942	NAD+ binding site [chemical binding]; other site
502801007943	substrate binding site [chemical binding]; other site
502801007944	Zn binding site [ion binding]; other site
502801007945	fructokinase; Reviewed; Region: PRK09557
502801007946	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
502801007947	nucleotide binding site [chemical binding]; other site
502801007948	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
502801007949	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
502801007950	FtsX-like permease family; Region: FtsX; pfam02687
502801007951	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
502801007952	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
502801007953	Walker A/P-loop; other site
502801007954	ATP binding site [chemical binding]; other site
502801007955	Q-loop/lid; other site
502801007956	ABC transporter signature motif; other site
502801007957	Walker B; other site
502801007958	D-loop; other site
502801007959	H-loop/switch region; other site
502801007960	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
502801007961	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
502801007962	FtsX-like permease family; Region: FtsX; pfam02687
502801007963	transcription-repair coupling factor; Provisional; Region: PRK10689
502801007964	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
502801007965	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
502801007966	ATP binding site [chemical binding]; other site
502801007967	putative Mg++ binding site [ion binding]; other site
502801007968	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801007969	nucleotide binding region [chemical binding]; other site
502801007970	ATP-binding site [chemical binding]; other site
502801007971	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
502801007972	hypothetical protein; Provisional; Region: PRK11280
502801007973	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
502801007974	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
502801007975	hypothetical protein; Provisional; Region: PRK04940
502801007976	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
502801007977	beta-hexosaminidase; Provisional; Region: PRK05337
502801007978	thiamine kinase; Region: ycfN_thiK; TIGR02721
502801007979	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
502801007980	active site
502801007981	substrate binding site [chemical binding]; other site
502801007982	ATP binding site [chemical binding]; other site
502801007983	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
502801007984	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
502801007985	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
502801007986	putative dimer interface [polypeptide binding]; other site
502801007987	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
502801007988	nucleotide binding site/active site [active]
502801007989	HIT family signature motif; other site
502801007990	catalytic residue [active]
502801007991	shikimate 5-dehydrogenase; Reviewed; Region: PRK12550
502801007992	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
502801007993	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
502801007994	shikimate binding site; other site
502801007995	NAD(P) binding site [chemical binding]; other site
502801007996	AAA domain; Region: AAA_23; pfam13476
502801007997	Domain of unknown function (DUF4297); Region: DUF4297; pfam14130
502801007998	Phage-related protein [Function unknown]; Region: COG4695; cl01923
502801007999	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
502801008000	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
502801008001	Protein of unknown function (DUF2778); Region: DUF2778; pfam10908
502801008002	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
502801008003	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
502801008004	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
502801008005	active site turn [active]
502801008006	phosphorylation site [posttranslational modification]
502801008007	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
502801008008	active site
502801008009	DNA polymerase III subunit delta'; Validated; Region: PRK07993
502801008010	DNA polymerase III subunit delta'; Validated; Region: PRK08485
502801008011	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
502801008012	thymidylate kinase; Validated; Region: tmk; PRK00698
502801008013	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
502801008014	TMP-binding site; other site
502801008015	ATP-binding site [chemical binding]; other site
502801008016	Aminodeoxychorismate lyase [Coenzyme transport and metabolism]; Region: COG1559
502801008017	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
502801008018	dimerization interface [polypeptide binding]; other site
502801008019	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
502801008020	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
502801008021	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801008022	catalytic residue [active]
502801008023	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
502801008024	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
502801008025	dimer interface [polypeptide binding]; other site
502801008026	active site
502801008027	acyl carrier protein; Provisional; Region: acpP; PRK00982
502801008028	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
502801008029	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
502801008030	NAD(P) binding site [chemical binding]; other site
502801008031	homotetramer interface [polypeptide binding]; other site
502801008032	homodimer interface [polypeptide binding]; other site
502801008033	active site
502801008034	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
502801008035	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
502801008036	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
502801008037	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
502801008038	dimer interface [polypeptide binding]; other site
502801008039	active site
502801008040	CoA binding pocket [chemical binding]; other site
502801008041	Fatty acid/phospholipid biosynthesis enzyme [Lipid metabolism]; Region: PlsX; COG0416
502801008042	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
502801008043	hypothetical protein; Provisional; Region: PRK11193
502801008044	Maf-like protein; Region: Maf; pfam02545
502801008045	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
502801008046	active site
502801008047	dimer interface [polypeptide binding]; other site
502801008048	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
502801008049	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
502801008050	RNA binding surface [nucleotide binding]; other site
502801008051	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
502801008052	active site
502801008053	Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530
502801008054	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
502801008055	homodimer interface [polypeptide binding]; other site
502801008056	oligonucleotide binding site [chemical binding]; other site
502801008057	Uncharacterized conserved protein [Function unknown]; Region: COG1359
502801008058	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
502801008059	active site
502801008060	substrate binding pocket [chemical binding]; other site
502801008061	dimer interface [polypeptide binding]; other site
502801008062	DNA damage-inducible protein I; Provisional; Region: PRK10597
502801008063	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
502801008064	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
502801008065	hydroxyglutarate oxidase; Provisional; Region: PRK11728
502801008066	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
502801008067	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
502801008068	MULE transposase domain; Region: MULE; pfam10551
502801008069	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801008070	dimerization interface [polypeptide binding]; other site
502801008071	DNA binding residues [nucleotide binding]
502801008072	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
502801008073	Domain of unknown function DUF20; Region: UPF0118; pfam01594
502801008074	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
502801008075	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
502801008076	active site residue [active]
502801008077	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
502801008078	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
502801008079	putative acyl-acceptor binding pocket; other site
502801008080	amino acid/peptide transporter (Peptide:H+ symporter), bacterial; Region: yjdL_sub1_fam; TIGR00924
502801008081	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801008082	putative substrate translocation pore; other site
502801008083	POT family; Region: PTR2; cl17359
502801008084	lipoprotein; Provisional; Region: PRK10175
502801008085	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
502801008086	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
502801008087	Ligand binding site; other site
502801008088	DXD motif; other site
502801008089	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
502801008090	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; cl15433
502801008091	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
502801008092	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
502801008093	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
502801008094	TrkA-C domain; Region: TrkA_C; pfam02080
502801008095	Transporter associated domain; Region: CorC_HlyC; smart01091
502801008096	EamA-like transporter family; Region: EamA; pfam00892
502801008097	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
502801008098	EamA-like transporter family; Region: EamA; pfam00892
502801008099	Autoinducer synthetase; Region: Autoind_synth; pfam00765
502801008100	Autoinducer binding domain; Region: Autoind_bind; pfam03472
502801008101	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801008102	DNA binding residues [nucleotide binding]
502801008103	dimerization interface [polypeptide binding]; other site
502801008104	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
502801008105	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801008106	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
502801008107	dimerization interface [polypeptide binding]; other site
502801008108	benzoate transport; Region: 2A0115; TIGR00895
502801008109	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801008110	putative substrate translocation pore; other site
502801008111	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801008112	Formaldehyde-activating enzyme nesessary for methanogenesis [Energy    production and conversion]; Region: COG1795
502801008113	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
502801008114	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
502801008115	active site
502801008116	catalytic tetrad [active]
502801008117	CRISPR/Cas system-associated RAMP superfamily protein Cas6f; Region: Cas6_I-F; cd09674
502801008118	CRISPR/Cas system-associated RAMP superfamily protein Csy3; Region: Csy3_I-F; cd09737
502801008119	CRISPR/Cas system-associated RAMP superfamily protein Csy2; Region: Csy2_I-F; cd09676
502801008120	CRISPR/Cas system-associated protein Csy1; Region: Csy1_I-F; cd09735
502801008121	CRISPR/Cas system-associated protein Cas3/Cas2; Region: Cas3_Cas2_I-F; cd09673
502801008122	CRISPR-associated helicase Cas3, subtype I-F/YPEST; Region: cas3_yersinia; TIGR02562
502801008123	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-F; cd09718
502801008124	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
502801008125	Mechanosensitive ion channel; Region: MS_channel; pfam00924
502801008126	Protein of unknown function (DUF1861); Region: DUF1861; pfam08950
502801008127	Predicted glycosylase [Carbohydrate transport and metabolism]; Region: COG2152
502801008128	active site
502801008129	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
502801008130	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801008131	dimer interface [polypeptide binding]; other site
502801008132	conserved gate region; other site
502801008133	putative PBP binding loops; other site
502801008134	ABC-ATPase subunit interface; other site
502801008135	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
502801008136	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801008137	dimer interface [polypeptide binding]; other site
502801008138	putative PBP binding loops; other site
502801008139	ABC-ATPase subunit interface; other site
502801008140	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
502801008141	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
502801008142	Transcriptional regulators [Transcription]; Region: PurR; COG1609
502801008143	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801008144	DNA binding site [nucleotide binding]
502801008145	domain linker motif; other site
502801008146	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_3; cd06279
502801008147	putative dimerization interface [polypeptide binding]; other site
502801008148	putative ligand binding site [chemical binding]; other site
502801008149	phosphomannomutase CpsG; Provisional; Region: PRK15414
502801008150	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
502801008151	active site
502801008152	substrate binding site [chemical binding]; other site
502801008153	metal binding site [ion binding]; metal-binding site
502801008154	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
502801008155	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
502801008156	Walker A/P-loop; other site
502801008157	ATP binding site [chemical binding]; other site
502801008158	Q-loop/lid; other site
502801008159	ABC transporter signature motif; other site
502801008160	Walker B; other site
502801008161	D-loop; other site
502801008162	H-loop/switch region; other site
502801008163	TOBE domain; Region: TOBE_2; pfam08402
502801008164	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4304
502801008165	haemagglutination activity domain; Region: Haemagg_act; pfam05860
502801008166	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
502801008167	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801008168	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801008169	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
502801008170	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
502801008171	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
502801008172	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
502801008173	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
502801008174	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
502801008175	FMN-binding pocket [chemical binding]; other site
502801008176	flavin binding motif; other site
502801008177	phosphate binding motif [ion binding]; other site
502801008178	beta-alpha-beta structure motif; other site
502801008179	NAD binding pocket [chemical binding]; other site
502801008180	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
502801008181	catalytic loop [active]
502801008182	iron binding site [ion binding]; other site
502801008183	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
502801008184	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
502801008185	[2Fe-2S] cluster binding site [ion binding]; other site
502801008186	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
502801008187	putative alpha subunit interface [polypeptide binding]; other site
502801008188	putative active site [active]
502801008189	putative substrate binding site [chemical binding]; other site
502801008190	Fe binding site [ion binding]; other site
502801008191	putative transporter; Provisional; Region: PRK09950
502801008192	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801008193	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
502801008194	tartrate dehydrogenase; Region: TTC; TIGR02089
502801008195	transcriptional activator TtdR; Provisional; Region: PRK09801
502801008196	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801008197	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
502801008198	putative effector binding pocket; other site
502801008199	putative dimerization interface [polypeptide binding]; other site
502801008200	Transcriptional regulators [Transcription]; Region: PurR; COG1609
502801008201	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801008202	DNA binding site [nucleotide binding]
502801008203	domain linker motif; other site
502801008204	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
502801008205	dimerization interface [polypeptide binding]; other site
502801008206	ligand binding site [chemical binding]; other site
502801008207	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801008208	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801008209	TM-ABC transporter signature motif; other site
502801008210	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801008211	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801008212	Walker A/P-loop; other site
502801008213	ATP binding site [chemical binding]; other site
502801008214	Q-loop/lid; other site
502801008215	ABC transporter signature motif; other site
502801008216	Walker B; other site
502801008217	D-loop; other site
502801008218	H-loop/switch region; other site
502801008219	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801008220	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
502801008221	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321
502801008222	putative ligand binding site [chemical binding]; other site
502801008223	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
502801008224	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH2; cd08256
502801008225	putative NAD(P) binding site [chemical binding]; other site
502801008226	catalytic Zn binding site [ion binding]; other site
502801008227	structural Zn binding site [ion binding]; other site
502801008228	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
502801008229	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: COG3965
502801008230	outer membrane protein X; Provisional; Region: ompX; PRK09408
502801008231	threonine and homoserine efflux system; Provisional; Region: PRK10532
502801008232	putative acetyltransferase YhhY; Provisional; Region: PRK10140
502801008233	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
502801008234	Coenzyme A binding pocket [chemical binding]; other site
502801008235	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
502801008236	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801008237	S-adenosylmethionine binding site [chemical binding]; other site
502801008238	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
502801008239	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
502801008240	dimerization interface [polypeptide binding]; other site
502801008241	DPS ferroxidase diiron center [ion binding]; other site
502801008242	ion pore; other site
502801008243	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
502801008244	TPR motif; other site
502801008245	binding surface
502801008246	Uncharacterized conserved protein [Function unknown]; Region: COG1434
502801008247	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
502801008248	putative active site [active]
502801008249	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
502801008250	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801008251	substrate binding pocket [chemical binding]; other site
502801008252	membrane-bound complex binding site; other site
502801008253	hinge residues; other site
502801008254	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
502801008255	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801008256	dimer interface [polypeptide binding]; other site
502801008257	conserved gate region; other site
502801008258	putative PBP binding loops; other site
502801008259	ABC-ATPase subunit interface; other site
502801008260	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
502801008261	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
502801008262	Walker A/P-loop; other site
502801008263	ATP binding site [chemical binding]; other site
502801008264	Q-loop/lid; other site
502801008265	ABC transporter signature motif; other site
502801008266	Walker B; other site
502801008267	D-loop; other site
502801008268	H-loop/switch region; other site
502801008269	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
502801008270	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
502801008271	putative active site [active]
502801008272	heme pocket [chemical binding]; other site
502801008273	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
502801008274	putative active site [active]
502801008275	heme pocket [chemical binding]; other site
502801008276	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
502801008277	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
502801008278	dimer interface [polypeptide binding]; other site
502801008279	putative CheW interface [polypeptide binding]; other site
502801008280	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
502801008281	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801008282	S-adenosylmethionine binding site [chemical binding]; other site
502801008283	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
502801008284	glycosyl transferase family protein; Provisional; Region: PRK08136
502801008285	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
502801008286	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
502801008287	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
502801008288	acyl-activating enzyme (AAE) consensus motif; other site
502801008289	putative AMP binding site [chemical binding]; other site
502801008290	putative active site [active]
502801008291	putative CoA binding site [chemical binding]; other site
502801008292	O-succinylbenzoate synthase; Provisional; Region: PRK05105
502801008293	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
502801008294	active site
502801008295	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
502801008296	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
502801008297	substrate binding site [chemical binding]; other site
502801008298	oxyanion hole (OAH) forming residues; other site
502801008299	trimer interface [polypeptide binding]; other site
502801008300	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
502801008301	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
502801008302	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
502801008303	dimer interface [polypeptide binding]; other site
502801008304	tetramer interface [polypeptide binding]; other site
502801008305	PYR/PP interface [polypeptide binding]; other site
502801008306	TPP binding site [chemical binding]; other site
502801008307	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
502801008308	TPP-binding site; other site
502801008309	Isochorismate synthase [Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: MenF; COG1169
502801008310	chorismate binding enzyme; Region: Chorismate_bind; cl10555
502801008311	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
502801008312	phosphogluconate dehydratase; Validated; Region: PRK09054
502801008313	6-phosphogluconate dehydratase; Region: edd; TIGR01196
502801008314	Domain of unknown function (DUF336); Region: DUF336; cl01249
502801008315	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801008316	D-galactonate transporter; Region: 2A0114; TIGR00893
502801008317	putative substrate translocation pore; other site
502801008318	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
502801008319	Hydroxy(phenyl)pyruvate Reductase, D-isomer-specific 2-hydroxyacid-related dehydrogenase; Region: HPPR; cd12156
502801008320	putative ligand binding site [chemical binding]; other site
502801008321	NAD binding site [chemical binding]; other site
502801008322	catalytic site [active]
502801008323	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
502801008324	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801008325	DNA binding site [nucleotide binding]
502801008326	domain linker motif; other site
502801008327	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
502801008328	putative ligand binding site [chemical binding]; other site
502801008329	putative dimerization interface [polypeptide binding]; other site
502801008330	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
502801008331	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
502801008332	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
502801008333	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
502801008334	NADP binding site [chemical binding]; other site
502801008335	homodimer interface [polypeptide binding]; other site
502801008336	active site
502801008337	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
502801008338	AAA domain; Region: AAA_33; pfam13671
502801008339	ATP-binding site [chemical binding]; other site
502801008340	Gluconate-6-phosphate binding site [chemical binding]; other site
502801008341	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
502801008342	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
502801008343	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
502801008344	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
502801008345	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
502801008346	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
502801008347	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
502801008348	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
502801008349	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
502801008350	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
502801008351	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
502801008352	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
502801008353	4Fe-4S binding domain; Region: Fer4; pfam00037
502801008354	4Fe-4S binding domain; Region: Fer4; pfam00037
502801008355	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
502801008356	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
502801008357	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
502801008358	catalytic loop [active]
502801008359	iron binding site [ion binding]; other site
502801008360	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
502801008361	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
502801008362	[4Fe-4S] binding site [ion binding]; other site
502801008363	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
502801008364	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
502801008365	SLBB domain; Region: SLBB; pfam10531
502801008366	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
502801008367	NADH dehydrogenase subunit E; Validated; Region: PRK07539
502801008368	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
502801008369	putative dimer interface [polypeptide binding]; other site
502801008370	[2Fe-2S] cluster binding site [ion binding]; other site
502801008371	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
502801008372	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
502801008373	NADH dehydrogenase subunit D; Validated; Region: PRK06075
502801008374	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
502801008375	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
502801008376	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
502801008377	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801008378	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
502801008379	putative dimerization interface [polypeptide binding]; other site
502801008380	aminotransferase AlaT; Validated; Region: PRK09265
502801008381	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801008382	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801008383	homodimer interface [polypeptide binding]; other site
502801008384	catalytic residue [active]
502801008385	5'-nucleotidase; Provisional; Region: PRK03826
502801008386	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
502801008387	transmembrane helices; other site
502801008388	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
502801008389	TrkA-C domain; Region: TrkA_C; pfam02080
502801008390	TrkA-C domain; Region: TrkA_C; pfam02080
502801008391	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
502801008392	putative phosphatase; Provisional; Region: PRK11587
502801008393	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801008394	motif II; other site
502801008395	hypothetical protein; Validated; Region: PRK05445
502801008396	hypothetical protein; Provisional; Region: PRK01816
502801008397	propionate/acetate kinase; Provisional; Region: PRK12379
502801008398	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
502801008399	phosphate acetyltransferase; Reviewed; Region: PRK05632
502801008400	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
502801008401	DRTGG domain; Region: DRTGG; pfam07085
502801008402	phosphate acetyltransferase; Region: pta; TIGR00651
502801008403	Transcriptional regulators [Transcription]; Region: PurR; COG1609
502801008404	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801008405	DNA binding site [nucleotide binding]
502801008406	domain linker motif; other site
502801008407	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
502801008408	putative dimerization interface [polypeptide binding]; other site
502801008409	putative ligand binding site [chemical binding]; other site
502801008410	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
502801008411	active site
502801008412	phosphorylation site [posttranslational modification]
502801008413	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
502801008414	active site
502801008415	P-loop; other site
502801008416	phosphorylation site [posttranslational modification]
502801008417	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
502801008418	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
502801008419	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
502801008420	nudix motif; other site
502801008421	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
502801008422	active site
502801008423	metal binding site [ion binding]; metal-binding site
502801008424	homotetramer interface [polypeptide binding]; other site
502801008425	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
502801008426	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
502801008427	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
502801008428	putative NAD(P) binding site [chemical binding]; other site
502801008429	putative active site [active]
502801008430	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
502801008431	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
502801008432	Walker A/P-loop; other site
502801008433	ATP binding site [chemical binding]; other site
502801008434	Q-loop/lid; other site
502801008435	ABC transporter signature motif; other site
502801008436	Walker B; other site
502801008437	D-loop; other site
502801008438	H-loop/switch region; other site
502801008439	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
502801008440	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801008441	dimer interface [polypeptide binding]; other site
502801008442	conserved gate region; other site
502801008443	putative PBP binding loops; other site
502801008444	ABC-ATPase subunit interface; other site
502801008445	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
502801008446	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801008447	dimer interface [polypeptide binding]; other site
502801008448	conserved gate region; other site
502801008449	putative PBP binding loops; other site
502801008450	ABC-ATPase subunit interface; other site
502801008451	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
502801008452	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801008453	substrate binding pocket [chemical binding]; other site
502801008454	membrane-bound complex binding site; other site
502801008455	hinge residues; other site
502801008456	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
502801008457	Flavoprotein; Region: Flavoprotein; pfam02441
502801008458	amidophosphoribosyltransferase; Provisional; Region: PRK09246
502801008459	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
502801008460	active site
502801008461	tetramer interface [polypeptide binding]; other site
502801008462	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
502801008463	active site
502801008464	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
502801008465	colicin V production protein; Provisional; Region: PRK10845
502801008466	cell division protein DedD; Provisional; Region: PRK11633
502801008467	Sporulation related domain; Region: SPOR; pfam05036
502801008468	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
502801008469	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
502801008470	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
502801008471	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
502801008472	hypothetical protein; Provisional; Region: PRK10847
502801008473	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
502801008474	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
502801008475	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
502801008476	dimerization interface 3.5A [polypeptide binding]; other site
502801008477	active site
502801008478	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
502801008479	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
502801008480	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
502801008481	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
502801008482	ligand binding site [chemical binding]; other site
502801008483	NAD binding site [chemical binding]; other site
502801008484	catalytic site [active]
502801008485	homodimer interface [polypeptide binding]; other site
502801008486	Cupin domain; Region: Cupin_2; pfam07883
502801008487	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
502801008488	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801008489	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
502801008490	EamA-like transporter family; Region: EamA; pfam00892
502801008491	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
502801008492	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
502801008493	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
502801008494	aspartate racemase; Region: asp_race; TIGR00035
502801008495	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
502801008496	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
502801008497	dimer interface [polypeptide binding]; other site
502801008498	active site
502801008499	Uncharacterized conserved protein [Function unknown]; Region: COG4121
502801008500	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
502801008501	hydroxyglutarate oxidase; Provisional; Region: PRK11728
502801008502	YfcL protein; Region: YfcL; pfam08891
502801008503	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
502801008504	hypothetical protein; Provisional; Region: PRK10621
502801008505	Predicted permeases [General function prediction only]; Region: COG0730
502801008506	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
502801008507	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
502801008508	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
502801008509	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
502801008510	Tetramer interface [polypeptide binding]; other site
502801008511	active site
502801008512	FMN-binding site [chemical binding]; other site
502801008513	HemK family putative methylases; Region: hemK_fam; TIGR00536
502801008514	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801008515	S-adenosylmethionine binding site [chemical binding]; other site
502801008516	hypothetical protein; Provisional; Region: PRK04946
502801008517	Smr domain; Region: Smr; pfam01713
502801008518	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
502801008519	catalytic core [active]
502801008520	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
502801008521	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
502801008522	substrate binding site [chemical binding]; other site
502801008523	oxyanion hole (OAH) forming residues; other site
502801008524	trimer interface [polypeptide binding]; other site
502801008525	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
502801008526	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
502801008527	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
502801008528	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
502801008529	dimer interface [polypeptide binding]; other site
502801008530	active site
502801008531	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
502801008532	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
502801008533	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
502801008534	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: COG4235
502801008535	cytochrome c-type biogenesis protein CcmI; Region: cytochro_ccmI; TIGR03142
502801008536	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
502801008537	binding surface
502801008538	TPR motif; other site
502801008539	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
502801008540	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
502801008541	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
502801008542	catalytic residues [active]
502801008543	central insert; other site
502801008544	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
502801008545	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
502801008546	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
502801008547	heme exporter protein CcmC; Region: ccmC; TIGR01191
502801008548	heme exporter protein CcmB; Region: ccmB; TIGR01190
502801008549	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
502801008550	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
502801008551	Walker A/P-loop; other site
502801008552	ATP binding site [chemical binding]; other site
502801008553	Q-loop/lid; other site
502801008554	ABC transporter signature motif; other site
502801008555	Walker B; other site
502801008556	D-loop; other site
502801008557	H-loop/switch region; other site
502801008558	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
502801008559	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
502801008560	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
502801008561	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
502801008562	PhnA protein; Region: PhnA; pfam03831
502801008563	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
502801008564	Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455
502801008565	ImpE protein; Region: ImpE; pfam07024
502801008566	PAAR motif; Region: PAAR_motif; pfam05488
502801008567	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501
502801008568	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
502801008569	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
502801008570	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
502801008571	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
502801008572	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
502801008573	hypothetical protein; Provisional; Region: PRK08126
502801008574	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
502801008575	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
502801008576	ligand binding site [chemical binding]; other site
502801008577	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
502801008578	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
502801008579	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
502801008580	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
502801008581	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
502801008582	Protein of unknown function (DUF877); Region: DUF877; pfam05943
502801008583	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
502801008584	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
502801008585	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
502801008586	PapC N-terminal domain; Region: PapC_N; pfam13954
502801008587	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
502801008588	PapC C-terminal domain; Region: PapC_C; pfam13953
502801008589	putative chaperone protein EcpD; Provisional; Region: PRK09926
502801008590	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801008591	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
502801008592	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
502801008593	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
502801008594	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801008595	Walker A motif; other site
502801008596	ATP binding site [chemical binding]; other site
502801008597	Walker B motif; other site
502801008598	arginine finger; other site
502801008599	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801008600	Walker A motif; other site
502801008601	ATP binding site [chemical binding]; other site
502801008602	Walker B motif; other site
502801008603	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
502801008604	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
502801008605	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
502801008606	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
502801008607	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
502801008608	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
502801008609	Fimbrial protein; Region: Fimbrial; pfam00419
502801008610	Glycosyltransferase (GlcNAc); Region: GlcNAc; pfam11397
502801008611	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
502801008612	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
502801008613	ligand binding site [chemical binding]; other site
502801008614	Uncharacterized conserved protein [Function unknown]; Region: COG5435
502801008615	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
502801008616	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801008617	DNA binding residues [nucleotide binding]
502801008618	dimerization interface [polypeptide binding]; other site
502801008619	Membrane-bound lytic murein transglycosylase B [Cell envelope biogenesis, outer membrane]; Region: MltB; COG2951
502801008620	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
502801008621	N-acetyl-D-glucosamine binding site [chemical binding]; other site
502801008622	catalytic residue [active]
502801008623	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
502801008624	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
502801008625	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
502801008626	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801008627	dimer interface [polypeptide binding]; other site
502801008628	conserved gate region; other site
502801008629	putative PBP binding loops; other site
502801008630	ABC-ATPase subunit interface; other site
502801008631	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801008632	dimer interface [polypeptide binding]; other site
502801008633	conserved gate region; other site
502801008634	putative PBP binding loops; other site
502801008635	ABC-ATPase subunit interface; other site
502801008636	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
502801008637	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
502801008638	Walker A/P-loop; other site
502801008639	ATP binding site [chemical binding]; other site
502801008640	Q-loop/lid; other site
502801008641	ABC transporter signature motif; other site
502801008642	Walker B; other site
502801008643	D-loop; other site
502801008644	H-loop/switch region; other site
502801008645	Predicted membrane protein [Function unknown]; Region: COG4331
502801008646	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
502801008647	Protein of unknown function (DUF4225); Region: DUF4225; pfam13988
502801008648	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
502801008649	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
502801008650	putative [Fe4-S4] binding site [ion binding]; other site
502801008651	putative molybdopterin cofactor binding site [chemical binding]; other site
502801008652	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
502801008653	putative molybdopterin cofactor binding site; other site
502801008654	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
502801008655	4Fe-4S binding domain; Region: Fer4; cl02805
502801008656	DMSO reductase anchor subunit [General function prediction only]; Region: DmsC; COG3302
502801008657	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
502801008658	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
502801008659	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4380
502801008660	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4259
502801008661	Uncharacterized protein involved in formation of curli polymers [Cell envelope biogenesis, outer membrane]; Region: CsgG; COG1462
502801008662	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
502801008663	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
502801008664	aminotransferase; Validated; Region: PRK08175
502801008665	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801008666	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801008667	homodimer interface [polypeptide binding]; other site
502801008668	catalytic residue [active]
502801008669	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
502801008670	glucokinase, proteobacterial type; Region: glk; TIGR00749
502801008671	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
502801008672	nucleotide binding site [chemical binding]; other site
502801008673	Predicted membrane protein [Function unknown]; Region: COG4125
502801008674	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
502801008675	Bacterial Transmembrane Pair family; Region: BTP; pfam05232
502801008676	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801008677	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801008678	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
502801008679	dimerization interface [polypeptide binding]; other site
502801008680	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
502801008681	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
502801008682	active site
502801008683	catalytic tetrad [active]
502801008684	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
502801008685	manganese transport protein MntH; Reviewed; Region: PRK00701
502801008686	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
502801008687	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
502801008688	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
502801008689	Nucleoside recognition; Region: Gate; pfam07670
502801008690	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
502801008691	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
502801008692	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
502801008693	HIGH motif; other site
502801008694	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
502801008695	active site
502801008696	KMSKS motif; other site
502801008697	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3575
502801008698	FlxA-like protein; Region: FlxA; pfam14282
502801008699	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
502801008700	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
502801008701	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
502801008702	nucleotide binding pocket [chemical binding]; other site
502801008703	K-X-D-G motif; other site
502801008704	catalytic site [active]
502801008705	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
502801008706	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
502801008707	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
502801008708	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
502801008709	Dimer interface [polypeptide binding]; other site
502801008710	BRCT sequence motif; other site
502801008711	cell division protein ZipA; Provisional; Region: PRK03427
502801008712	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
502801008713	FtsZ protein binding site [polypeptide binding]; other site
502801008714	putative sulfate transport protein CysZ; Validated; Region: PRK04949
502801008715	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
502801008716	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
502801008717	dimer interface [polypeptide binding]; other site
502801008718	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801008719	catalytic residue [active]
502801008720	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
502801008721	dimerization domain swap beta strand [polypeptide binding]; other site
502801008722	regulatory protein interface [polypeptide binding]; other site
502801008723	active site
502801008724	regulatory phosphorylation site [posttranslational modification]; other site
502801008725	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
502801008726	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
502801008727	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
502801008728	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
502801008729	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
502801008730	HPr interaction site; other site
502801008731	glycerol kinase (GK) interaction site [polypeptide binding]; other site
502801008732	active site
502801008733	phosphorylation site [posttranslational modification]
502801008734	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801008735	dimerization interface [polypeptide binding]; other site
502801008736	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801008737	dimer interface [polypeptide binding]; other site
502801008738	phosphorylation site [posttranslational modification]
502801008739	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801008740	ATP binding site [chemical binding]; other site
502801008741	Mg2+ binding site [ion binding]; other site
502801008742	G-X-G motif; other site
502801008743	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
502801008744	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801008745	active site
502801008746	phosphorylation site [posttranslational modification]
502801008747	intermolecular recognition site; other site
502801008748	dimerization interface [polypeptide binding]; other site
502801008749	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801008750	DNA binding site [nucleotide binding]
502801008751	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
502801008752	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801008753	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801008754	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
502801008755	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
502801008756	Walker A/P-loop; other site
502801008757	ATP binding site [chemical binding]; other site
502801008758	Q-loop/lid; other site
502801008759	ABC transporter signature motif; other site
502801008760	Walker B; other site
502801008761	D-loop; other site
502801008762	H-loop/switch region; other site
502801008763	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
502801008764	FtsX-like permease family; Region: FtsX; pfam02687
502801008765	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
502801008766	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
502801008767	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
502801008768	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
502801008769	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
502801008770	active site residue [active]
502801008771	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
502801008772	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
502801008773	Na binding site [ion binding]; other site
502801008774	Protein of unknown function (DUF3311); Region: DUF3311; pfam11755
502801008775	putative peptidase; Provisional; Region: PRK14575
502801008776	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
502801008777	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
502801008778	active site
502801008779	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
502801008780	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801008781	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801008782	homodimer interface [polypeptide binding]; other site
502801008783	catalytic residue [active]
502801008784	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
502801008785	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
502801008786	metal ion-dependent adhesion site (MIDAS); other site
502801008787	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
502801008788	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801008789	dimer interface [polypeptide binding]; other site
502801008790	phosphorylation site [posttranslational modification]
502801008791	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801008792	ATP binding site [chemical binding]; other site
502801008793	Mg2+ binding site [ion binding]; other site
502801008794	G-X-G motif; other site
502801008795	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
502801008796	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801008797	active site
502801008798	phosphorylation site [posttranslational modification]
502801008799	intermolecular recognition site; other site
502801008800	dimerization interface [polypeptide binding]; other site
502801008801	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801008802	DNA binding site [nucleotide binding]
502801008803	type III secretion protein GogB; Provisional; Region: PRK15386
502801008804	cysteine synthase B; Region: cysM; TIGR01138
502801008805	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
502801008806	dimer interface [polypeptide binding]; other site
502801008807	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801008808	catalytic residue [active]
502801008809	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
502801008810	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
502801008811	Walker A/P-loop; other site
502801008812	ATP binding site [chemical binding]; other site
502801008813	Q-loop/lid; other site
502801008814	ABC transporter signature motif; other site
502801008815	Walker B; other site
502801008816	D-loop; other site
502801008817	H-loop/switch region; other site
502801008818	TOBE-like domain; Region: TOBE_3; pfam12857
502801008819	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801008820	dimer interface [polypeptide binding]; other site
502801008821	conserved gate region; other site
502801008822	putative PBP binding loops; other site
502801008823	ABC-ATPase subunit interface; other site
502801008824	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
502801008825	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801008826	dimer interface [polypeptide binding]; other site
502801008827	conserved gate region; other site
502801008828	putative PBP binding loops; other site
502801008829	ABC-ATPase subunit interface; other site
502801008830	thiosulfate transporter subunit; Provisional; Region: PRK10852
502801008831	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
502801008832	putative sialic acid transporter; Provisional; Region: PRK03893
502801008833	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801008834	putative substrate translocation pore; other site
502801008835	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
502801008836	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
502801008837	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
502801008838	putative active site [active]
502801008839	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
502801008840	N-acetylmannosamine kinase; Provisional; Region: PRK05082
502801008841	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
502801008842	nucleotide binding site [chemical binding]; other site
502801008843	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
502801008844	Leucine rich repeat; Region: LRR_8; pfam13855
502801008845	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
502801008846	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
502801008847	putative active site cavity [active]
502801008848	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
502801008849	Class I aldolases; Region: Aldolase_Class_I; cl17187
502801008850	catalytic residue [active]
502801008851	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
502801008852	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
502801008853	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
502801008854	Periplasmic protein with OB-fold [Function unknown]; Region: COG3111
502801008855	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
502801008856	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
502801008857	Autotransporter beta-domain; Region: Autotransporter; pfam03797
502801008858	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
502801008859	Predicted nucleotidyltransferase [General function prediction    only]; Region: COG4849
502801008860	Helix-turn-helix domains; Region: HTH; cl00088
502801008861	DDE superfamily endonuclease; Region: DDE_3; pfam13358
502801008862	putative acetyltransferase; Provisional; Region: PRK03624
502801008863	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
502801008864	Coenzyme A binding pocket [chemical binding]; other site
502801008865	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
502801008866	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
502801008867	hypothetical protein; Validated; Region: PRK00124
502801008868	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
502801008869	Malic enzyme, N-terminal domain; Region: malic; pfam00390
502801008870	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
502801008871	putative NAD(P) binding site [chemical binding]; other site
502801008872	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
502801008873	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
502801008874	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
502801008875	dimer interface [polypeptide binding]; other site
502801008876	ADP-ribose binding site [chemical binding]; other site
502801008877	active site
502801008878	nudix motif; other site
502801008879	metal binding site [ion binding]; metal-binding site
502801008880	cytochrome c-type protein NapC; Provisional; Region: PRK10617
502801008881	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
502801008882	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
502801008883	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
502801008884	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
502801008885	[4Fe-4S] binding site [ion binding]; other site
502801008886	molybdopterin cofactor binding site; other site
502801008887	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
502801008888	molybdopterin cofactor binding site; other site
502801008889	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
502801008890	ferredoxin-type protein; Provisional; Region: PRK10194
502801008891	transcriptional regulator NarP; Provisional; Region: PRK10403
502801008892	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801008893	active site
502801008894	phosphorylation site [posttranslational modification]
502801008895	intermolecular recognition site; other site
502801008896	dimerization interface [polypeptide binding]; other site
502801008897	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801008898	DNA binding residues [nucleotide binding]
502801008899	dimerization interface [polypeptide binding]; other site
502801008900	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4519
502801008901	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
502801008902	Protein export membrane protein; Region: SecD_SecF; cl14618
502801008903	Protein export membrane protein; Region: SecD_SecF; cl14618
502801008904	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
502801008905	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
502801008906	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801008907	FeS/SAM binding site; other site
502801008908	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
502801008909	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
502801008910	Sulfatase; Region: Sulfatase; pfam00884
502801008911	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
502801008912	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
502801008913	Walker A/P-loop; other site
502801008914	ATP binding site [chemical binding]; other site
502801008915	Q-loop/lid; other site
502801008916	ABC transporter signature motif; other site
502801008917	Walker B; other site
502801008918	D-loop; other site
502801008919	H-loop/switch region; other site
502801008920	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
502801008921	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801008922	dimer interface [polypeptide binding]; other site
502801008923	conserved gate region; other site
502801008924	ABC-ATPase subunit interface; other site
502801008925	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801008926	dimer interface [polypeptide binding]; other site
502801008927	conserved gate region; other site
502801008928	putative PBP binding loops; other site
502801008929	ABC-ATPase subunit interface; other site
502801008930	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
502801008931	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
502801008932	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
502801008933	TPR motif; other site
502801008934	Tetratrico peptide repeat; Region: TPR_5; pfam12688
502801008935	binding surface
502801008936	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
502801008937	ArsC family; Region: ArsC; pfam03960
502801008938	putative catalytic residues [active]
502801008939	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
502801008940	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
502801008941	metal binding site [ion binding]; metal-binding site
502801008942	dimer interface [polypeptide binding]; other site
502801008943	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
502801008944	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
502801008945	Uncharacterized protein family (UPF0370); Region: UPF0370; pfam13980
502801008946	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
502801008947	Domain of unknown function (DUF1726); Region: DUF1726; pfam08351
502801008948	Helicase; Region: Helicase_RecD; pfam05127
502801008949	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
502801008950	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
502801008951	Predicted membrane protein [Function unknown]; Region: COG2707
502801008952	Predicted metalloprotease [General function prediction only]; Region: COG2321
502801008953	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
502801008954	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
502801008955	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
502801008956	ATP binding site [chemical binding]; other site
502801008957	active site
502801008958	substrate binding site [chemical binding]; other site
502801008959	lipoprotein; Provisional; Region: PRK11679
502801008960	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
502801008961	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
502801008962	dihydrodipicolinate synthase; Region: dapA; TIGR00674
502801008963	dimer interface [polypeptide binding]; other site
502801008964	active site
502801008965	catalytic residue [active]
502801008966	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
502801008967	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
502801008968	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
502801008969	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
502801008970	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
502801008971	catalytic triad [active]
502801008972	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
502801008973	Domain of unknown function DUF20; Region: UPF0118; pfam01594
502801008974	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
502801008975	Peptidase family M48; Region: Peptidase_M48; pfam01435
502801008976	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
502801008977	TPR motif; other site
502801008978	binding surface
502801008979	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
502801008980	ArsC family; Region: ArsC; pfam03960
502801008981	catalytic residues [active]
502801008982	DNA replication initiation factor; Provisional; Region: PRK08084
502801008983	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
502801008984	uracil transporter; Provisional; Region: PRK10720
502801008985	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
502801008986	active site
502801008987	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
502801008988	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
502801008989	dimerization interface [polypeptide binding]; other site
502801008990	putative ATP binding site [chemical binding]; other site
502801008991	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
502801008992	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
502801008993	active site
502801008994	substrate binding site [chemical binding]; other site
502801008995	cosubstrate binding site; other site
502801008996	catalytic site [active]
502801008997	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
502801008998	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
502801008999	Flagellin N-methylase; Region: FliB; pfam03692
502801009000	phosphate transporter ATP-binding protein; Provisional; Region: PRK14236
502801009001	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
502801009002	Walker A/P-loop; other site
502801009003	ATP binding site [chemical binding]; other site
502801009004	Q-loop/lid; other site
502801009005	ABC transporter signature motif; other site
502801009006	Walker B; other site
502801009007	D-loop; other site
502801009008	H-loop/switch region; other site
502801009009	ABC-type phosphate transport system, auxiliary component [Inorganic ion transport and metabolism]; Region: COG4985
502801009010	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
502801009011	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801009012	dimer interface [polypeptide binding]; other site
502801009013	conserved gate region; other site
502801009014	putative PBP binding loops; other site
502801009015	ABC-ATPase subunit interface; other site
502801009016	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4590
502801009017	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801009018	conserved gate region; other site
502801009019	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801009020	dimer interface [polypeptide binding]; other site
502801009021	conserved gate region; other site
502801009022	putative PBP binding loops; other site
502801009023	ABC-ATPase subunit interface; other site
502801009024	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
502801009025	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
502801009026	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
502801009027	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
502801009028	putative active site [active]
502801009029	catalytic site [active]
502801009030	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
502801009031	domain interface [polypeptide binding]; other site
502801009032	active site
502801009033	catalytic site [active]
502801009034	exopolyphosphatase; Provisional; Region: PRK10854
502801009035	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
502801009036	nucleotide binding site [chemical binding]; other site
502801009037	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
502801009038	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
502801009039	MgtE intracellular N domain; Region: MgtE_N; smart00924
502801009040	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
502801009041	Divalent cation transporter; Region: MgtE; cl00786
502801009042	putative chaperone; Provisional; Region: PRK11678
502801009043	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
502801009044	nucleotide binding site [chemical binding]; other site
502801009045	putative NEF/HSP70 interaction site [polypeptide binding]; other site
502801009046	SBD interface [polypeptide binding]; other site
502801009047	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
502801009048	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801009049	dimer interface [polypeptide binding]; other site
502801009050	conserved gate region; other site
502801009051	putative PBP binding loops; other site
502801009052	ABC-ATPase subunit interface; other site
502801009053	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801009054	dimer interface [polypeptide binding]; other site
502801009055	conserved gate region; other site
502801009056	putative PBP binding loops; other site
502801009057	ABC-ATPase subunit interface; other site
502801009058	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
502801009059	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
502801009060	4-aminobutyrate aminotransferase; Provisional; Region: PRK06777
502801009061	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
502801009062	inhibitor-cofactor binding pocket; inhibition site
502801009063	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801009064	catalytic residue [active]
502801009065	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
502801009066	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801009067	DNA-binding site [nucleotide binding]; DNA binding site
502801009068	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801009069	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801009070	homodimer interface [polypeptide binding]; other site
502801009071	catalytic residue [active]
502801009072	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
502801009073	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
502801009074	Walker A/P-loop; other site
502801009075	ATP binding site [chemical binding]; other site
502801009076	Q-loop/lid; other site
502801009077	ABC transporter signature motif; other site
502801009078	Walker B; other site
502801009079	D-loop; other site
502801009080	H-loop/switch region; other site
502801009081	TOBE domain; Region: TOBE_2; pfam08402
502801009082	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
502801009083	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801009084	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801009085	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
502801009086	Protein export membrane protein; Region: SecD_SecF; cl14618
502801009087	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
502801009088	putative transporter; Provisional; Region: PRK10504
502801009089	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801009090	putative substrate translocation pore; other site
502801009091	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
502801009092	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801009093	dimerization interface [polypeptide binding]; other site
502801009094	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801009095	dimer interface [polypeptide binding]; other site
502801009096	phosphorylation site [posttranslational modification]
502801009097	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801009098	ATP binding site [chemical binding]; other site
502801009099	Mg2+ binding site [ion binding]; other site
502801009100	G-X-G motif; other site
502801009101	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
502801009102	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801009103	active site
502801009104	phosphorylation site [posttranslational modification]
502801009105	intermolecular recognition site; other site
502801009106	dimerization interface [polypeptide binding]; other site
502801009107	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801009108	DNA binding site [nucleotide binding]
502801009109	Uncharacterized conserved protein [Function unknown]; Region: COG3422
502801009110	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
502801009111	putative protease; Provisional; Region: PRK15452
502801009112	Peptidase family U32; Region: Peptidase_U32; pfam01136
502801009113	lipid kinase; Reviewed; Region: PRK13054
502801009114	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
502801009115	Inhibitor of vertebrate lysozyme (Ivy); Region: Ivy; pfam08816
502801009116	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
502801009117	substrate binding site [chemical binding]; other site
502801009118	dimer interface [polypeptide binding]; other site
502801009119	ATP binding site [chemical binding]; other site
502801009120	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
502801009121	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
502801009122	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
502801009123	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
502801009124	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
502801009125	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
502801009126	GMP synthase; Reviewed; Region: guaA; PRK00074
502801009127	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
502801009128	AMP/PPi binding site [chemical binding]; other site
502801009129	candidate oxyanion hole; other site
502801009130	catalytic triad [active]
502801009131	potential glutamine specificity residues [chemical binding]; other site
502801009132	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
502801009133	ATP Binding subdomain [chemical binding]; other site
502801009134	Ligand Binding sites [chemical binding]; other site
502801009135	Dimerization subdomain; other site
502801009136	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
502801009137	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
502801009138	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
502801009139	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
502801009140	active site
502801009141	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
502801009142	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
502801009143	generic binding surface II; other site
502801009144	generic binding surface I; other site
502801009145	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
502801009146	Predicted permeases [General function prediction only]; Region: COG0679
502801009147	GTP-binding protein Der; Reviewed; Region: PRK00093
502801009148	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
502801009149	G1 box; other site
502801009150	GTP/Mg2+ binding site [chemical binding]; other site
502801009151	Switch I region; other site
502801009152	G2 box; other site
502801009153	Switch II region; other site
502801009154	G3 box; other site
502801009155	G4 box; other site
502801009156	G5 box; other site
502801009157	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
502801009158	G1 box; other site
502801009159	GTP/Mg2+ binding site [chemical binding]; other site
502801009160	Switch I region; other site
502801009161	G2 box; other site
502801009162	G3 box; other site
502801009163	Switch II region; other site
502801009164	G4 box; other site
502801009165	G5 box; other site
502801009166	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
502801009167	Beta-barrel assembly machinery (Bam) complex component B and related proteins; Region: BamB_YfgL; cd10276
502801009168	Trp docking motif [polypeptide binding]; other site
502801009169	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
502801009170	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
502801009171	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
502801009172	dimer interface [polypeptide binding]; other site
502801009173	motif 1; other site
502801009174	active site
502801009175	motif 2; other site
502801009176	motif 3; other site
502801009177	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
502801009178	anticodon binding site; other site
502801009179	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
502801009180	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
502801009181	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
502801009182	cytoskeletal protein RodZ; Provisional; Region: PRK10856
502801009183	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
502801009184	non-specific DNA binding site [nucleotide binding]; other site
502801009185	salt bridge; other site
502801009186	sequence-specific DNA binding site [nucleotide binding]; other site
502801009187	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
502801009188	Tfp pilus assembly protein PilF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilF; COG3063
502801009189	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
502801009190	binding surface
502801009191	TPR motif; other site
502801009192	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
502801009193	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801009194	FeS/SAM binding site; other site
502801009195	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
502801009196	active site
502801009197	multimer interface [polypeptide binding]; other site
502801009198	Protein of unkown function (DUF1881); Region: DUF1881; pfam08964
502801009199	Beta/Gamma crystallin; Region: Crystall; cl02528
502801009200	Beta/Gamma crystallin; Region: Crystall; cl02528
502801009201	Exotoxin A binding; Region: Exotox-A_bind; pfam09101
502801009202	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
502801009203	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
502801009204	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
502801009205	Autotransporter beta-domain; Region: Autotransporter; pfam03797
502801009206	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
502801009207	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
502801009208	Autotransporter beta-domain; Region: Autotransporter; pfam03797
502801009209	SseB protein; Region: SseB; pfam07179
502801009210	aminopeptidase B; Provisional; Region: PRK05015
502801009211	Peptidase; Region: DUF3663; pfam12404
502801009212	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
502801009213	interface (dimer of trimers) [polypeptide binding]; other site
502801009214	Substrate-binding/catalytic site; other site
502801009215	Zn-binding sites [ion binding]; other site
502801009216	hypothetical protein; Provisional; Region: PRK10721
502801009217	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
502801009218	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
502801009219	catalytic loop [active]
502801009220	iron binding site [ion binding]; other site
502801009221	chaperone protein HscA; Provisional; Region: hscA; PRK05183
502801009222	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
502801009223	nucleotide binding site [chemical binding]; other site
502801009224	putative NEF/HSP70 interaction site [polypeptide binding]; other site
502801009225	SBD interface [polypeptide binding]; other site
502801009226	co-chaperone HscB; Provisional; Region: hscB; PRK05014
502801009227	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
502801009228	HSP70 interaction site [polypeptide binding]; other site
502801009229	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
502801009230	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
502801009231	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
502801009232	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
502801009233	trimerization site [polypeptide binding]; other site
502801009234	active site
502801009235	cysteine desulfurase; Provisional; Region: PRK14012
502801009236	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
502801009237	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801009238	catalytic residue [active]
502801009239	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
502801009240	Rrf2 family protein; Region: rrf2_super; TIGR00738
502801009241	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
502801009242	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
502801009243	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
502801009244	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
502801009245	active site
502801009246	dimerization interface [polypeptide binding]; other site
502801009247	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG2215
502801009248	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG3683
502801009249	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
502801009250	PRD domain; Region: PRD; pfam00874
502801009251	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
502801009252	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801009253	putative substrate translocation pore; other site
502801009254	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
502801009255	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
502801009256	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
502801009257	dimer interface [polypeptide binding]; other site
502801009258	active site
502801009259	glycine-pyridoxal phosphate binding site [chemical binding]; other site
502801009260	folate binding site [chemical binding]; other site
502801009261	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
502801009262	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
502801009263	heme-binding site [chemical binding]; other site
502801009264	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
502801009265	FAD binding pocket [chemical binding]; other site
502801009266	FAD binding motif [chemical binding]; other site
502801009267	phosphate binding motif [ion binding]; other site
502801009268	beta-alpha-beta structure motif; other site
502801009269	NAD binding pocket [chemical binding]; other site
502801009270	Heme binding  pocket [chemical binding]; other site
502801009271	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801009272	DNA-binding site [nucleotide binding]; DNA binding site
502801009273	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
502801009274	Nitrogen regulatory protein P-II; Region: P-II; smart00938
502801009275	NAD synthetase; Provisional; Region: PRK13981
502801009276	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
502801009277	multimer interface [polypeptide binding]; other site
502801009278	active site
502801009279	catalytic triad [active]
502801009280	protein interface 1 [polypeptide binding]; other site
502801009281	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
502801009282	homodimer interface [polypeptide binding]; other site
502801009283	NAD binding pocket [chemical binding]; other site
502801009284	ATP binding pocket [chemical binding]; other site
502801009285	Mg binding site [ion binding]; other site
502801009286	active-site loop [active]
502801009287	response regulator GlrR; Provisional; Region: PRK15115
502801009288	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801009289	active site
502801009290	phosphorylation site [posttranslational modification]
502801009291	intermolecular recognition site; other site
502801009292	dimerization interface [polypeptide binding]; other site
502801009293	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801009294	Walker A motif; other site
502801009295	ATP binding site [chemical binding]; other site
502801009296	Walker B motif; other site
502801009297	arginine finger; other site
502801009298	hypothetical protein; Provisional; Region: PRK10722
502801009299	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
502801009300	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801009301	dimer interface [polypeptide binding]; other site
502801009302	phosphorylation site [posttranslational modification]
502801009303	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801009304	ATP binding site [chemical binding]; other site
502801009305	Mg2+ binding site [ion binding]; other site
502801009306	G-X-G motif; other site
502801009307	N-acetylglucosamine-binding protein A; Reviewed; Region: PRK13211
502801009308	N-acetylglucosamine-binding protein A; Reviewed; Region: PRK13211
502801009309	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
502801009310	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
502801009311	dimerization interface [polypeptide binding]; other site
502801009312	ATP binding site [chemical binding]; other site
502801009313	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
502801009314	dimerization interface [polypeptide binding]; other site
502801009315	ATP binding site [chemical binding]; other site
502801009316	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
502801009317	putative active site [active]
502801009318	catalytic triad [active]
502801009319	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
502801009320	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801009321	substrate binding pocket [chemical binding]; other site
502801009322	membrane-bound complex binding site; other site
502801009323	hinge residues; other site
502801009324	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
502801009325	N-acetyl-D-glucosamine binding site [chemical binding]; other site
502801009326	catalytic residue [active]
502801009327	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
502801009328	nucleoside/Zn binding site; other site
502801009329	dimer interface [polypeptide binding]; other site
502801009330	catalytic motif [active]
502801009331	haloacid dehalogenase superfamily, subfamily IF hydrolase, YfhB; Region: YfhB_g-proteo; TIGR01545
502801009332	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
502801009333	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
502801009334	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
502801009335	putative active site [active]
502801009336	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
502801009337	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
502801009338	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
502801009339	putative active site [active]
502801009340	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
502801009341	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
502801009342	active site
502801009343	hydrophilic channel; other site
502801009344	dimerization interface [polypeptide binding]; other site
502801009345	catalytic residues [active]
502801009346	active site lid [active]
502801009347	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
502801009348	Recombination protein O N terminal; Region: RecO_N; pfam11967
502801009349	Recombination protein O C terminal; Region: RecO_C; pfam02565
502801009350	GTPase Era; Reviewed; Region: era; PRK00089
502801009351	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
502801009352	G1 box; other site
502801009353	GTP/Mg2+ binding site [chemical binding]; other site
502801009354	Switch I region; other site
502801009355	G2 box; other site
502801009356	Switch II region; other site
502801009357	G3 box; other site
502801009358	G4 box; other site
502801009359	G5 box; other site
502801009360	KH domain; Region: KH_2; pfam07650
502801009361	ribonuclease III; Reviewed; Region: rnc; PRK00102
502801009362	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
502801009363	dimerization interface [polypeptide binding]; other site
502801009364	active site
502801009365	metal binding site [ion binding]; metal-binding site
502801009366	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
502801009367	dsRNA binding site [nucleotide binding]; other site
502801009368	signal peptidase I; Provisional; Region: PRK10861
502801009369	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
502801009370	Catalytic site [active]
502801009371	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
502801009372	GTP-binding protein LepA; Provisional; Region: PRK05433
502801009373	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
502801009374	G1 box; other site
502801009375	putative GEF interaction site [polypeptide binding]; other site
502801009376	GTP/Mg2+ binding site [chemical binding]; other site
502801009377	Switch I region; other site
502801009378	G2 box; other site
502801009379	G3 box; other site
502801009380	Switch II region; other site
502801009381	G4 box; other site
502801009382	G5 box; other site
502801009383	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
502801009384	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
502801009385	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
502801009386	SoxR reducing system protein RseC; Provisional; Region: PRK10862
502801009387	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
502801009388	anti-sigma E factor; Provisional; Region: rseB; PRK09455
502801009389	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
502801009390	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
502801009391	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
502801009392	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
502801009393	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
502801009394	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
502801009395	DNA binding residues [nucleotide binding]
502801009396	L-aspartate oxidase; Provisional; Region: PRK09077
502801009397	L-aspartate oxidase; Provisional; Region: PRK06175
502801009398	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
502801009399	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
502801009400	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801009401	S-adenosylmethionine binding site [chemical binding]; other site
502801009402	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
502801009403	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
502801009404	ATP binding site [chemical binding]; other site
502801009405	Mg++ binding site [ion binding]; other site
502801009406	motif III; other site
502801009407	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
502801009408	nucleotide binding region [chemical binding]; other site
502801009409	ATP-binding site [chemical binding]; other site
502801009410	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
502801009411	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
502801009412	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
502801009413	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
502801009414	nucleophilic elbow; other site
502801009415	catalytic triad; other site
502801009416	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
502801009417	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
502801009418	ligand binding site [chemical binding]; other site
502801009419	active site
502801009420	UGI interface [polypeptide binding]; other site
502801009421	catalytic site [active]
502801009422	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
502801009423	putative substrate binding pocket [chemical binding]; other site
502801009424	AC domain interface; other site
502801009425	catalytic triad [active]
502801009426	AB domain interface; other site
502801009427	interchain disulfide; other site
502801009428	Predicted membrane protein [Function unknown]; Region: COG3817
502801009429	Protein of unknown function (DUF979); Region: DUF979; pfam06166
502801009430	Predicted membrane protein [Function unknown]; Region: COG3819
502801009431	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
502801009432	putative active site [active]
502801009433	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
502801009434	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
502801009435	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; cl00896
502801009436	Uncharacterized conserved protein [Function unknown]; Region: COG0327
502801009437	metal-binding protein; Provisional; Region: PRK10799
502801009438	cAMP phosphodiesterases class-II; Region: PDEase_II; cl17776
502801009439	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
502801009440	DNA photolyase; Region: DNA_photolyase; pfam00875
502801009441	hypothetical protein; Provisional; Region: PRK10167
502801009442	Uncharacterized conserved protein [Function unknown]; Region: COG3272
502801009443	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
502801009444	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
502801009445	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
502801009446	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
502801009447	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
502801009448	sensor protein KdpD; Provisional; Region: PRK10490
502801009449	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
502801009450	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
502801009451	Ligand Binding Site [chemical binding]; other site
502801009452	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
502801009453	GAF domain; Region: GAF_3; pfam13492
502801009454	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801009455	dimer interface [polypeptide binding]; other site
502801009456	phosphorylation site [posttranslational modification]
502801009457	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801009458	ATP binding site [chemical binding]; other site
502801009459	Mg2+ binding site [ion binding]; other site
502801009460	G-X-G motif; other site
502801009461	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
502801009462	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801009463	active site
502801009464	phosphorylation site [posttranslational modification]
502801009465	intermolecular recognition site; other site
502801009466	dimerization interface [polypeptide binding]; other site
502801009467	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801009468	DNA binding site [nucleotide binding]
502801009469	Predicted membrane protein [Function unknown]; Region: COG2510
502801009470	phosphoglucomutase; Validated; Region: PRK07564
502801009471	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
502801009472	active site
502801009473	substrate binding site [chemical binding]; other site
502801009474	metal binding site [ion binding]; metal-binding site
502801009475	replication initiation regulator SeqA; Provisional; Region: PRK11187
502801009476	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
502801009477	Protein of unknown function (DUF1311); Region: DUF1311; pfam07007
502801009478	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
502801009479	putative active site [active]
502801009480	YdjC motif; other site
502801009481	Mg binding site [ion binding]; other site
502801009482	putative homodimer interface [polypeptide binding]; other site
502801009483	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
502801009484	Cupin domain; Region: Cupin_2; cl17218
502801009485	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801009486	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
502801009487	methionine cluster; other site
502801009488	active site
502801009489	phosphorylation site [posttranslational modification]
502801009490	metal binding site [ion binding]; metal-binding site
502801009491	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
502801009492	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
502801009493	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
502801009494	active site
502801009495	P-loop; other site
502801009496	phosphorylation site [posttranslational modification]
502801009497	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
502801009498	camphor resistance protein CrcB; Provisional; Region: ccrB; PRK01636
502801009499	voltage-gated potassium channel; Provisional; Region: PRK10537
502801009500	Ion channel; Region: Ion_trans_2; pfam07885
502801009501	TrkA-N domain; Region: TrkA_N; pfam02254
502801009502	acid-resistance protein; Provisional; Region: hdeB; PRK11566
502801009503	High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376
502801009504	Urea transporter [Amino acid transport and metabolism]; Region: Utp; COG4413
502801009505	UreD urease accessory protein; Region: UreD; pfam01774
502801009506	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase [Posttranslational modification, protein turnover, chaperones / Transcription]; Region: HypB; COG0378
502801009507	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
502801009508	UreF; Region: UreF; pfam01730
502801009509	urease accessory protein UreE; Provisional; Region: ureE; PRK14711
502801009510	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
502801009511	dimer interface [polypeptide binding]; other site
502801009512	catalytic residues [active]
502801009513	urease subunit alpha; Reviewed; Region: ureC; PRK13309
502801009514	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
502801009515	subunit interactions [polypeptide binding]; other site
502801009516	active site
502801009517	flap region; other site
502801009518	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
502801009519	alpha-beta subunit interface [polypeptide binding]; other site
502801009520	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
502801009521	alpha-gamma subunit interface [polypeptide binding]; other site
502801009522	beta-gamma subunit interface [polypeptide binding]; other site
502801009523	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
502801009524	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801009525	Walker A/P-loop; other site
502801009526	ATP binding site [chemical binding]; other site
502801009527	Q-loop/lid; other site
502801009528	ABC transporter signature motif; other site
502801009529	Walker B; other site
502801009530	D-loop; other site
502801009531	H-loop/switch region; other site
502801009532	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801009533	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
502801009534	Walker A/P-loop; other site
502801009535	ATP binding site [chemical binding]; other site
502801009536	Q-loop/lid; other site
502801009537	ABC transporter signature motif; other site
502801009538	Walker B; other site
502801009539	D-loop; other site
502801009540	H-loop/switch region; other site
502801009541	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
502801009542	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801009543	dimer interface [polypeptide binding]; other site
502801009544	conserved gate region; other site
502801009545	putative PBP binding loops; other site
502801009546	ABC-ATPase subunit interface; other site
502801009547	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
502801009548	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801009549	dimer interface [polypeptide binding]; other site
502801009550	conserved gate region; other site
502801009551	putative PBP binding loops; other site
502801009552	ABC-ATPase subunit interface; other site
502801009553	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
502801009554	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
502801009555	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
502801009556	DNA-binding site [nucleotide binding]; DNA binding site
502801009557	RNA-binding motif; other site
502801009558	MbeD/MobD like; Region: MbeD_MobD; pfam04899
502801009559	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
502801009560	hypothetical protein; Provisional; Region: PRK10556
502801009561	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
502801009562	catalytic residues [active]
502801009563	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
502801009564	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
502801009565	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
502801009566	Class I ribonucleotide reductase; Region: RNR_I; cd01679
502801009567	active site
502801009568	dimer interface [polypeptide binding]; other site
502801009569	catalytic residues [active]
502801009570	effector binding site; other site
502801009571	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
502801009572	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
502801009573	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
502801009574	dimer interface [polypeptide binding]; other site
502801009575	putative radical transfer pathway; other site
502801009576	diiron center [ion binding]; other site
502801009577	tyrosyl radical; other site
502801009578	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
502801009579	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
502801009580	Walker A/P-loop; other site
502801009581	ATP binding site [chemical binding]; other site
502801009582	Q-loop/lid; other site
502801009583	ABC transporter signature motif; other site
502801009584	Walker B; other site
502801009585	D-loop; other site
502801009586	H-loop/switch region; other site
502801009587	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
502801009588	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
502801009589	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801009590	dimer interface [polypeptide binding]; other site
502801009591	conserved gate region; other site
502801009592	putative PBP binding loops; other site
502801009593	ABC-ATPase subunit interface; other site
502801009594	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
502801009595	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
502801009596	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801009597	putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212
502801009598	Catalytic domain of bacterial PuuE allantoinases, Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1), and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977
502801009599	active site
502801009600	catalytic site [active]
502801009601	tetramer interface [polypeptide binding]; other site
502801009602	uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain; Region: SLC-NCS1sbd_u1; cd11555
502801009603	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
502801009604	Na binding site [ion binding]; other site
502801009605	putative substrate binding site [chemical binding]; other site
502801009606	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
502801009607	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
502801009608	active site
502801009609	catalytic site [active]
502801009610	substrate binding site [chemical binding]; other site
502801009611	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
502801009612	RNA/DNA hybrid binding site [nucleotide binding]; other site
502801009613	active site
502801009614	Methyltransferase domain; Region: Methyltransf_11; pfam08241
502801009615	hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413
502801009616	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
502801009617	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
502801009618	N-acetyl-D-glucosamine binding site [chemical binding]; other site
502801009619	catalytic residue [active]
502801009620	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
502801009621	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
502801009622	hypothetical protein; Provisional; Region: PRK05421
502801009623	putative catalytic site [active]
502801009624	putative phosphate binding site [ion binding]; other site
502801009625	putative metal binding site [ion binding]; other site
502801009626	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
502801009627	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
502801009628	active site
502801009629	catalytic tetrad [active]
502801009630	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
502801009631	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801009632	active site
502801009633	motif I; other site
502801009634	motif II; other site
502801009635	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
502801009636	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
502801009637	Walker A/P-loop; other site
502801009638	ATP binding site [chemical binding]; other site
502801009639	Q-loop/lid; other site
502801009640	ABC transporter signature motif; other site
502801009641	Walker B; other site
502801009642	D-loop; other site
502801009643	H-loop/switch region; other site
502801009644	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
502801009645	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801009646	dimer interface [polypeptide binding]; other site
502801009647	conserved gate region; other site
502801009648	ABC-ATPase subunit interface; other site
502801009649	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
502801009650	lipoprotein, YaeC family; Region: TIGR00363
502801009651	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
502801009652	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
502801009653	homodimer interaction site [polypeptide binding]; other site
502801009654	cofactor binding site; other site
502801009655	prolyl-tRNA synthetase; Provisional; Region: PRK09194
502801009656	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
502801009657	dimer interface [polypeptide binding]; other site
502801009658	motif 1; other site
502801009659	active site
502801009660	motif 2; other site
502801009661	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
502801009662	putative deacylase active site [active]
502801009663	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
502801009664	active site
502801009665	motif 3; other site
502801009666	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
502801009667	anticodon binding site; other site
502801009668	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
502801009669	NlpE N-terminal domain; Region: NlpE; pfam04170
502801009670	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
502801009671	hypothetical protein; Provisional; Region: PRK09256
502801009672	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
502801009673	hypothetical protein; Provisional; Region: PRK04964
502801009674	Rho-binding antiterminator; Provisional; Region: PRK11625
502801009675	Cytochrome c553 [Energy production and conversion]; Region: COG2863
502801009676	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
502801009677	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
502801009678	Ligand Binding Site [chemical binding]; other site
502801009679	TilS substrate binding domain; Region: TilS; pfam09179
502801009680	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
502801009681	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
502801009682	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
502801009683	putative metal binding site [ion binding]; other site
502801009684	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
502801009685	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
502801009686	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
502801009687	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
502801009688	putative active site [active]
502801009689	putative PHP Thumb interface [polypeptide binding]; other site
502801009690	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
502801009691	generic binding surface II; other site
502801009692	generic binding surface I; other site
502801009693	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
502801009694	RNA/DNA hybrid binding site [nucleotide binding]; other site
502801009695	active site
502801009696	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
502801009697	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
502801009698	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
502801009699	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
502801009700	active site
502801009701	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
502801009702	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
502801009703	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
502801009704	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
502801009705	trimer interface [polypeptide binding]; other site
502801009706	active site
502801009707	UDP-GlcNAc binding site [chemical binding]; other site
502801009708	lipid binding site [chemical binding]; lipid-binding site
502801009709	periplasmic chaperone; Provisional; Region: PRK10780
502801009710	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
502801009711	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
502801009712	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
502801009713	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
502801009714	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
502801009715	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
502801009716	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
502801009717	Surface antigen; Region: Bac_surface_Ag; pfam01103
502801009718	zinc metallopeptidase RseP; Provisional; Region: PRK10779
502801009719	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
502801009720	active site
502801009721	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
502801009722	protein binding site [polypeptide binding]; other site
502801009723	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
502801009724	protein binding site [polypeptide binding]; other site
502801009725	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
502801009726	putative substrate binding region [chemical binding]; other site
502801009727	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
502801009728	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
502801009729	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
502801009730	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
502801009731	catalytic residue [active]
502801009732	putative FPP diphosphate  binding site; other site
502801009733	putative FPP binding hydrophobic cleft; other site
502801009734	dimer interface [polypeptide binding]; other site
502801009735	putative IPP diphosphate binding site; other site
502801009736	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
502801009737	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
502801009738	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
502801009739	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
502801009740	ribosome recycling factor; Reviewed; Region: frr; PRK00083
502801009741	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
502801009742	hinge region; other site
502801009743	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
502801009744	putative nucleotide binding site [chemical binding]; other site
502801009745	uridine monophosphate binding site [chemical binding]; other site
502801009746	homohexameric interface [polypeptide binding]; other site
502801009747	elongation factor Ts; Provisional; Region: tsf; PRK09377
502801009748	UBA/TS-N domain; Region: UBA; pfam00627
502801009749	Elongation factor TS; Region: EF_TS; pfam00889
502801009750	Elongation factor TS; Region: EF_TS; pfam00889
502801009751	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
502801009752	rRNA interaction site [nucleotide binding]; other site
502801009753	S8 interaction site; other site
502801009754	putative laminin-1 binding site; other site
502801009755	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
502801009756	active site
502801009757	PII uridylyl-transferase; Provisional; Region: PRK05007
502801009758	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
502801009759	metal binding triad; other site
502801009760	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
502801009761	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
502801009762	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
502801009763	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
502801009764	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
502801009765	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
502801009766	trimer interface [polypeptide binding]; other site
502801009767	active site
502801009768	substrate binding site [chemical binding]; other site
502801009769	CoA binding site [chemical binding]; other site
502801009770	hypothetical protein; Provisional; Region: PRK13677
502801009771	flavodoxin; Provisional; Region: PRK08105
502801009772	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
502801009773	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
502801009774	probable active site [active]
502801009775	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
502801009776	SecY interacting protein Syd; Provisional; Region: PRK04968
502801009777	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
502801009778	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
502801009779	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
502801009780	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
502801009781	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
502801009782	flap endonuclease-like protein; Provisional; Region: PRK09482
502801009783	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
502801009784	active site
502801009785	metal binding site 1 [ion binding]; metal-binding site
502801009786	putative 5' ssDNA interaction site; other site
502801009787	metal binding site 3; metal-binding site
502801009788	metal binding site 2 [ion binding]; metal-binding site
502801009789	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
502801009790	putative DNA binding site [nucleotide binding]; other site
502801009791	putative metal binding site [ion binding]; other site
502801009792	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
502801009793	FtsJ-like methyltransferase; Region: FtsJ; cl17430
502801009794	hypothetical protein; Provisional; Region: PRK10873
502801009795	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
502801009796	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801009797	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
502801009798	dimerization interface [polypeptide binding]; other site
502801009799	substrate binding pocket [chemical binding]; other site
502801009800	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
502801009801	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
502801009802	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
502801009803	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801009804	catalytic residue [active]
502801009805	cysteine desulfurase, sulfur acceptor subunit CsdE; Region: FeS_syn_CsdE; TIGR03391
502801009806	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
502801009807	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
502801009808	putative ATP binding site [chemical binding]; other site
502801009809	putative substrate interface [chemical binding]; other site
502801009810	murein transglycosylase A; Provisional; Region: mltA; PRK11162
502801009811	MltA specific insert domain; Region: MltA; smart00925
502801009812	3D domain; Region: 3D; pfam06725
502801009813	AMIN domain; Region: AMIN; pfam11741
502801009814	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
502801009815	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
502801009816	active site
502801009817	metal binding site [ion binding]; metal-binding site
502801009818	N-acetylglutamate synthase; Validated; Region: PRK05279
502801009819	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
502801009820	putative feedback inhibition sensing region; other site
502801009821	putative nucleotide binding site [chemical binding]; other site
502801009822	putative substrate binding site [chemical binding]; other site
502801009823	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
502801009824	Coenzyme A binding pocket [chemical binding]; other site
502801009825	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
502801009826	AAA domain; Region: AAA_30; pfam13604
502801009827	Family description; Region: UvrD_C_2; pfam13538
502801009828	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
502801009829	protease3; Provisional; Region: PRK15101
502801009830	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
502801009831	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
502801009832	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
502801009833	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
502801009834	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
502801009835	hypothetical protein; Provisional; Region: PRK10332
502801009836	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
502801009837	Protein of unknown function (DUF2509); Region: DUF2509; pfam10713
502801009838	hypothetical protein; Provisional; Region: PRK10557
502801009839	hypothetical protein; Provisional; Region: PRK10506
502801009840	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
502801009841	thymidylate synthase; Reviewed; Region: thyA; PRK01827
502801009842	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
502801009843	dimerization interface [polypeptide binding]; other site
502801009844	active site
502801009845	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
502801009846	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
502801009847	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
502801009848	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
502801009849	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
502801009850	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
502801009851	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
502801009852	putative active site [active]
502801009853	Ap4A binding site [chemical binding]; other site
502801009854	nudix motif; other site
502801009855	putative metal binding site [ion binding]; other site
502801009856	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
502801009857	putative DNA-binding cleft [nucleotide binding]; other site
502801009858	putative DNA clevage site; other site
502801009859	molecular lever; other site
502801009860	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
502801009861	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
502801009862	active site
502801009863	catalytic tetrad [active]
502801009864	Uncharacterized protein conserved in bacteria (DUF2058); Region: DUF2058; cl01201
502801009865	lysophospholipid transporter LplT; Provisional; Region: PRK11195
502801009866	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801009867	putative substrate translocation pore; other site
502801009868	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
502801009869	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
502801009870	putative acyl-acceptor binding pocket; other site
502801009871	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
502801009872	acyl-activating enzyme (AAE) consensus motif; other site
502801009873	putative AMP binding site [chemical binding]; other site
502801009874	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
502801009875	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
502801009876	molybdopterin cofactor binding site [chemical binding]; other site
502801009877	substrate binding site [chemical binding]; other site
502801009878	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
502801009879	molybdopterin cofactor binding site; other site
502801009880	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
502801009881	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801009882	DNA binding site [nucleotide binding]
502801009883	domain linker motif; other site
502801009884	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
502801009885	dimerization interface (closed form) [polypeptide binding]; other site
502801009886	ligand binding site [chemical binding]; other site
502801009887	diaminopimelate decarboxylase; Provisional; Region: PRK11165
502801009888	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
502801009889	active site
502801009890	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
502801009891	substrate binding site [chemical binding]; other site
502801009892	catalytic residues [active]
502801009893	dimer interface [polypeptide binding]; other site
502801009894	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
502801009895	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801009896	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
502801009897	dimerization interface [polypeptide binding]; other site
502801009898	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801009899	putative substrate translocation pore; other site
502801009900	Major Facilitator Superfamily; Region: MFS_1; pfam07690
502801009901	transcriptional activator TtdR; Provisional; Region: PRK09801
502801009902	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801009903	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
502801009904	putative effector binding pocket; other site
502801009905	dimerization interface [polypeptide binding]; other site
502801009906	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
502801009907	Predicted protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: COG3531
502801009908	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
502801009909	catalytic residues [active]
502801009910	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
502801009911	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
502801009912	dimer interface [polypeptide binding]; other site
502801009913	ligand binding site [chemical binding]; other site
502801009914	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801009915	dimerization interface [polypeptide binding]; other site
502801009916	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
502801009917	dimer interface [polypeptide binding]; other site
502801009918	putative CheW interface [polypeptide binding]; other site
502801009919	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
502801009920	DNA binding site [nucleotide binding]
502801009921	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; pfam09691
502801009922	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
502801009923	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
502801009924	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
502801009925	Type II secretory pathway, component PulL [Intracellular trafficking and secretion]; Region: PulL; COG3297
502801009926	Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134
502801009927	GspL periplasmic domain; Region: GspL_C; pfam12693
502801009928	Type II secretory pathway, component PulK [Intracellular trafficking and secretion]; Region: PulK; COG3156
502801009929	Type II secretory pathway, component PulJ [Intracellular trafficking and secretion]; Region: PulJ; COG4795
502801009930	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
502801009931	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
502801009932	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
502801009933	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
502801009934	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
502801009935	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
502801009936	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
502801009937	type II secretion system protein F; Region: GspF; TIGR02120
502801009938	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
502801009939	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
502801009940	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
502801009941	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
502801009942	Walker A motif; other site
502801009943	ATP binding site [chemical binding]; other site
502801009944	Walker B motif; other site
502801009945	Type II secretory pathway, component PulD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulD; COG1450
502801009946	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
502801009947	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
502801009948	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
502801009949	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
502801009950	type II secretion system protein C; Region: typeII_sec_gspC; TIGR01713
502801009951	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
502801009952	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
502801009953	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
502801009954	active site clefts [active]
502801009955	zinc binding site [ion binding]; other site
502801009956	dimer interface [polypeptide binding]; other site
502801009957	Autotransporter beta-domain; Region: Autotransporter; pfam03797
502801009958	Lyase, N terminal; Region: Lyase_N; pfam09092
502801009959	Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues; Region: GAG_Lyase; cd01083
502801009960	substrate binding site [chemical binding]; other site
502801009961	catalytic residues [active]
502801009962	Sulfatase; Region: Sulfatase; cl17466
502801009963	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
502801009964	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
502801009965	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
502801009966	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
502801009967	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
502801009968	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
502801009969	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
502801009970	dimer interface [polypeptide binding]; other site
502801009971	active site
502801009972	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
502801009973	putative active site [active]
502801009974	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
502801009975	active site
502801009976	phosphorylation site [posttranslational modification]
502801009977	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
502801009978	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
502801009979	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
502801009980	active pocket/dimerization site; other site
502801009981	active site
502801009982	phosphorylation site [posttranslational modification]
502801009983	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
502801009984	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
502801009985	active site
502801009986	dimer interface [polypeptide binding]; other site
502801009987	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK12481
502801009988	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
502801009989	NADP binding site [chemical binding]; other site
502801009990	homodimer interface [polypeptide binding]; other site
502801009991	active site
502801009992	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
502801009993	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
502801009994	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801009995	FeS/SAM binding site; other site
502801009996	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
502801009997	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
502801009998	Sulfatase; Region: Sulfatase; pfam00884
502801009999	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4289
502801010000	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
502801010001	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
502801010002	intersubunit interface [polypeptide binding]; other site
502801010003	active site
502801010004	zinc binding site [ion binding]; other site
502801010005	Na+ binding site [ion binding]; other site
502801010006	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
502801010007	DJ-1 family protein; Region: not_thiJ; TIGR01383
502801010008	conserved cys residue [active]
502801010009	Transcriptional regulators [Transcription]; Region: PurR; COG1609
502801010010	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801010011	DNA binding site [nucleotide binding]
502801010012	domain linker motif; other site
502801010013	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
502801010014	dimerization interface [polypeptide binding]; other site
502801010015	ligand binding site [chemical binding]; other site
502801010016	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801010017	D-galactonate transporter; Region: 2A0114; TIGR00893
502801010018	putative substrate translocation pore; other site
502801010019	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
502801010020	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
502801010021	Glycosyl hydrolase family 31 (GH31) domain of a bacterial protein family represented by Escherichia coli protein Aec37. The gene encoding Aec37 (aec-37) is located within a genomic island (AGI-3) isolated from the extraintestinal avian pathogenic...; Region: GH31_glycosidase_Aec37; cd06599
502801010022	putative active site [active]
502801010023	putative catalytic site [active]
502801010024	lac repressor; Reviewed; Region: lacI; PRK09526
502801010025	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801010026	DNA binding site [nucleotide binding]
502801010027	domain linker motif; other site
502801010028	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
502801010029	ligand binding site [chemical binding]; other site
502801010030	dimerization interface (open form) [polypeptide binding]; other site
502801010031	dimerization interface (closed form) [polypeptide binding]; other site
502801010032	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
502801010033	trimer interface; other site
502801010034	sugar binding site [chemical binding]; other site
502801010035	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
502801010036	active site turn [active]
502801010037	phosphorylation site [posttranslational modification]
502801010038	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
502801010039	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
502801010040	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
502801010041	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
502801010042	Arabinogalactan endo-1,4-beta-galactosidase [Carbohydrate transport and metabolism]; Region: COG3867
502801010043	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
502801010044	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801010045	dimer interface [polypeptide binding]; other site
502801010046	conserved gate region; other site
502801010047	putative PBP binding loops; other site
502801010048	ABC-ATPase subunit interface; other site
502801010049	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801010050	dimer interface [polypeptide binding]; other site
502801010051	conserved gate region; other site
502801010052	ABC-ATPase subunit interface; other site
502801010053	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
502801010054	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
502801010055	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
502801010056	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
502801010057	Walker A/P-loop; other site
502801010058	ATP binding site [chemical binding]; other site
502801010059	Q-loop/lid; other site
502801010060	ABC transporter signature motif; other site
502801010061	Walker B; other site
502801010062	D-loop; other site
502801010063	H-loop/switch region; other site
502801010064	TOBE domain; Region: TOBE; cl01440
502801010065	TOBE domain; Region: TOBE_2; pfam08402
502801010066	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801010067	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801010068	Walker A/P-loop; other site
502801010069	ATP binding site [chemical binding]; other site
502801010070	Q-loop/lid; other site
502801010071	ABC transporter signature motif; other site
502801010072	Walker B; other site
502801010073	D-loop; other site
502801010074	H-loop/switch region; other site
502801010075	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801010076	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801010077	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801010078	TM-ABC transporter signature motif; other site
502801010079	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
502801010080	Periplasmic binding proteins specific to rhizopines; Region: PBP1_rhizopine_binding_like; cd06301
502801010081	putative ligand binding site [chemical binding]; other site
502801010082	hypothetical protein; Provisional; Region: PRK11479
502801010083	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
502801010084	Predicted transcriptional regulators [Transcription]; Region: COG1695
502801010085	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
502801010086	Domain of Unknown Function with PDB structure (DUF3861); Region: DUF3861; pfam12977
502801010087	PAAR motif; Region: PAAR_motif; pfam05488
502801010088	Protein of unknown function (DUF3142); Region: DUF3142; pfam11340
502801010089	Bacterial self-protective colicin-like immunity; Region: Colicin_immun; pfam09204
502801010090	Cysteine-rich CPCC; Region: Cys_rich_CPCC; pfam14206
502801010091	PAAR motif; Region: PAAR_motif; pfam05488
502801010092	Pyocin large subunit [General function prediction only]; Region: COG5529
502801010093	S-type Pyocin; Region: Pyocin_S; pfam06958
502801010094	Fic family protein [Function unknown]; Region: COG3177
502801010095	Fic/DOC family; Region: Fic; pfam02661
502801010096	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
502801010097	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
502801010098	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
502801010099	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
502801010100	D5 N terminal like; Region: D5_N; smart00885
502801010101	phage/plasmid primase, P4 family, C-terminal domain; Region: primase_Cterm; TIGR01613
502801010102	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
502801010103	antitoxin MqsA for MqsR toxin; Region: MqsA; cd12870
502801010104	toxin interface [polypeptide binding]; other site
502801010105	putative zinc finger/helix-turn-helix protein, YgiT family; Region: CxxCG_CxxCG_HTH; TIGR03830
502801010106	Zn binding site [ion binding]; other site
502801010107	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
502801010108	non-specific DNA binding site [nucleotide binding]; other site
502801010109	salt bridge; other site
502801010110	sequence-specific DNA binding site [nucleotide binding]; other site
502801010111	Motility quorum-sensing regulator (MqsR); Region: MqsR; cd12869
502801010112	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
502801010113	non-specific DNA binding site [nucleotide binding]; other site
502801010114	salt bridge; other site
502801010115	sequence-specific DNA binding site [nucleotide binding]; other site
502801010116	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
502801010117	integrase; Provisional; Region: int; PHA02601
502801010118	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
502801010119	active site
502801010120	DNA binding site [nucleotide binding]
502801010121	Int/Topo IB signature motif; other site
502801010122	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
502801010123	non-specific DNA binding site [nucleotide binding]; other site
502801010124	salt bridge; other site
502801010125	sequence-specific DNA binding site [nucleotide binding]; other site
502801010126	Regulatory phage protein cox; Region: Phage_Cox; pfam10743
502801010127	Domain of Unknown Function with PDB structure (DUF3850); Region: DUF3850; pfam12961
502801010128	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
502801010129	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
502801010130	active site
502801010131	catalytic site [active]
502801010132	substrate binding site [chemical binding]; other site
502801010133	'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The...; Region: SANT; cl17250
502801010134	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
502801010135	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
502801010136	Phage-related protein [Function unknown]; Region: COG4695; cl01923
502801010137	Phage portal protein; Region: Phage_portal; pfam04860
502801010138	terminase ATPase subunit; Provisional; Region: P; PHA02535
502801010139	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
502801010140	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
502801010141	Phage major capsid protein, P2 family; Region: Phage_cap_P2; cl04947
502801010142	terminase endonuclease subunit; Provisional; Region: M; PHA02537
502801010143	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
502801010144	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
502801010145	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
502801010146	Protein of unknown function (DUF2586); Region: DUF2586; pfam10758
502801010147	Protein of unknown function (DUF2597); Region: DUF2597; pfam10772
502801010148	Phage holin family 2; Region: Phage_holin_2; pfam04550
502801010149	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
502801010150	Protein of unknown function (DUF2765); Region: DUF2765; pfam10963
502801010151	Phage-related minor tail protein; Region: PhageMin_Tail; pfam10145
502801010152	Protein of unknown function (DUF2590); Region: DUF2590; pfam10761
502801010153	Baseplate J-like protein; Region: Baseplate_J; pfam04865
502801010154	histidinol-phosphate aminotransferase; Provisional; Region: PRK05166
502801010155	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
502801010156	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
502801010157	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
502801010158	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
502801010159	integrase; Provisional; Region: PRK09692
502801010160	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
502801010161	active site
502801010162	Int/Topo IB signature motif; other site
502801010163	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
502801010164	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
502801010165	dimer interface [polypeptide binding]; other site
502801010166	putative anticodon binding site; other site
502801010167	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
502801010168	motif 1; other site
502801010169	active site
502801010170	motif 2; other site
502801010171	motif 3; other site
502801010172	peptide chain release factor 2; Provisional; Region: PRK08787
502801010173	This domain is found in peptide chain release factors; Region: PCRF; smart00937
502801010174	RF-1 domain; Region: RF-1; pfam00472
502801010175	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
502801010176	DHH family; Region: DHH; pfam01368
502801010177	DHHA1 domain; Region: DHHA1; pfam02272
502801010178	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
502801010179	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
502801010180	dimerization domain [polypeptide binding]; other site
502801010181	dimer interface [polypeptide binding]; other site
502801010182	catalytic residues [active]
502801010183	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
502801010184	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
502801010185	active site
502801010186	Int/Topo IB signature motif; other site
502801010187	flavodoxin FldB; Provisional; Region: PRK12359
502801010188	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
502801010189	sensory histidine kinase CreC; Provisional; Region: PRK11100
502801010190	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801010191	dimer interface [polypeptide binding]; other site
502801010192	phosphorylation site [posttranslational modification]
502801010193	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801010194	ATP binding site [chemical binding]; other site
502801010195	Mg2+ binding site [ion binding]; other site
502801010196	G-X-G motif; other site
502801010197	DNA-binding response regulator CreB; Provisional; Region: PRK11083
502801010198	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801010199	active site
502801010200	phosphorylation site [posttranslational modification]
502801010201	intermolecular recognition site; other site
502801010202	dimerization interface [polypeptide binding]; other site
502801010203	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801010204	DNA binding site [nucleotide binding]
502801010205	hypothetical protein; Provisional; Region: PRK10878
502801010206	putative global regulator; Reviewed; Region: PRK09559
502801010207	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
502801010208	Predicted small integral membrane protein [Function unknown]; Region: COG5472
502801010209	hemolysin; Provisional; Region: PRK15087
502801010210	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
502801010211	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
502801010212	Haemagglutinin; Region: HIM; pfam05662
502801010213	YadA-like C-terminal region; Region: YadA; pfam03895
502801010214	Lipocalin-like domain; Region: Lipocalin_5; pfam13924
502801010215	glycine dehydrogenase; Provisional; Region: PRK05367
502801010216	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
502801010217	tetramer interface [polypeptide binding]; other site
502801010218	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801010219	catalytic residue [active]
502801010220	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
502801010221	tetramer interface [polypeptide binding]; other site
502801010222	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801010223	catalytic residue [active]
502801010224	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
502801010225	lipoyl attachment site [posttranslational modification]; other site
502801010226	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
502801010227	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
502801010228	oxidoreductase; Provisional; Region: PRK08013
502801010229	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
502801010230	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
502801010231	2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984
502801010232	proline aminopeptidase P II; Provisional; Region: PRK10879
502801010233	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
502801010234	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
502801010235	active site
502801010236	hypothetical protein; Reviewed; Region: PRK01736
502801010237	Z-ring-associated protein; Provisional; Region: PRK10972
502801010238	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
502801010239	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212; cl00360
502801010240	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
502801010241	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
502801010242	ligand binding site [chemical binding]; other site
502801010243	NAD binding site [chemical binding]; other site
502801010244	tetramer interface [polypeptide binding]; other site
502801010245	catalytic site [active]
502801010246	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
502801010247	L-serine binding site [chemical binding]; other site
502801010248	ACT domain interface; other site
502801010249	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
502801010250	tetramer (dimer of dimers) interface [polypeptide binding]; other site
502801010251	active site
502801010252	dimer interface [polypeptide binding]; other site
502801010253	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
502801010254	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801010255	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
502801010256	putative dimerization interface [polypeptide binding]; other site
502801010257	Uncharacterized conserved protein [Function unknown]; Region: COG2968
502801010258	oxidative stress defense protein; Provisional; Region: PRK11087
502801010259	arginine exporter protein; Provisional; Region: PRK09304
502801010260	mechanosensitive channel MscS; Provisional; Region: PRK10334
502801010261	Conserved TM helix; Region: TM_helix; pfam05552
502801010262	Mechanosensitive ion channel; Region: MS_channel; pfam00924
502801010263	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
502801010264	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
502801010265	active site
502801010266	intersubunit interface [polypeptide binding]; other site
502801010267	zinc binding site [ion binding]; other site
502801010268	Na+ binding site [ion binding]; other site
502801010269	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
502801010270	Phosphoglycerate kinase; Region: PGK; pfam00162
502801010271	substrate binding site [chemical binding]; other site
502801010272	hinge regions; other site
502801010273	ADP binding site [chemical binding]; other site
502801010274	catalytic site [active]
502801010275	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
502801010276	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
502801010277	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
502801010278	transketolase; Reviewed; Region: PRK12753
502801010279	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
502801010280	TPP-binding site [chemical binding]; other site
502801010281	dimer interface [polypeptide binding]; other site
502801010282	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
502801010283	PYR/PP interface [polypeptide binding]; other site
502801010284	dimer interface [polypeptide binding]; other site
502801010285	TPP binding site [chemical binding]; other site
502801010286	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
502801010287	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
502801010288	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
502801010289	[2Fe-2S] cluster binding site [ion binding]; other site
502801010290	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
502801010291	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
502801010292	dimer interface [polypeptide binding]; other site
502801010293	active site
502801010294	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
502801010295	catalytic residues [active]
502801010296	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
502801010297	S-adenosylmethionine synthetase; Validated; Region: PRK05250
502801010298	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
502801010299	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
502801010300	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
502801010301	hypothetical protein; Provisional; Region: PRK04860
502801010302	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
502801010303	DNA-specific endonuclease I; Provisional; Region: PRK15137
502801010304	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
502801010305	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
502801010306	RNA methyltransferase, RsmE family; Region: TIGR00046
502801010307	glutathione synthetase; Provisional; Region: PRK05246
502801010308	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
502801010309	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
502801010310	hypothetical protein; Validated; Region: PRK00228
502801010311	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
502801010312	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
502801010313	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
502801010314	putative active site; other site
502801010315	catalytic triad [active]
502801010316	putative dimer interface [polypeptide binding]; other site
502801010317	agmatine deiminase; Provisional; Region: PRK13551
502801010318	agmatine deiminase; Region: agmatine_aguA; TIGR03380
502801010319	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
502801010320	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
502801010321	Walker A motif; other site
502801010322	ATP binding site [chemical binding]; other site
502801010323	Walker B motif; other site
502801010324	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
502801010325	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
502801010326	catalytic residue [active]
502801010327	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
502801010328	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
502801010329	YGGT family; Region: YGGT; pfam02325
502801010330	Predicted integral membrane protein [Function unknown]; Region: COG0762
502801010331	hypothetical protein; Validated; Region: PRK05090
502801010332	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
502801010333	active site
502801010334	dimerization interface [polypeptide binding]; other site
502801010335	HemN family oxidoreductase; Provisional; Region: PRK05660
502801010336	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801010337	FeS/SAM binding site; other site
502801010338	HemN C-terminal domain; Region: HemN_C; pfam06969
502801010339	Peptidase C80 family; Region: Peptidase_C80; pfam11713
502801010340	Peptidase C80 family; Region: Peptidase_C80; pfam11713
502801010341	hypothetical protein; Provisional; Region: PRK10626
502801010342	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
502801010343	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
502801010344	glutaminase; Provisional; Region: PRK00971
502801010345	hypothetical protein; Provisional; Region: PRK11702
502801010346	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
502801010347	adenine DNA glycosylase; Provisional; Region: PRK10880
502801010348	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
502801010349	minor groove reading motif; other site
502801010350	helix-hairpin-helix signature motif; other site
502801010351	substrate binding pocket [chemical binding]; other site
502801010352	active site
502801010353	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
502801010354	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
502801010355	DNA binding and oxoG recognition site [nucleotide binding]
502801010356	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2924
502801010357	murein transglycosylase C; Provisional; Region: mltC; PRK11671
502801010358	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
502801010359	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
502801010360	N-acetyl-D-glucosamine binding site [chemical binding]; other site
502801010361	catalytic residue [active]
502801010362	ferrichrome/ferrioxamine B periplasmic transporter; Provisional; Region: PRK14048
502801010363	Periplasmic binding protein TroA_f.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_f; cd01139
502801010364	putative ligand binding residues [chemical binding]; other site
502801010365	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
502801010366	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801010367	N-terminal plug; other site
502801010368	ligand-binding site [chemical binding]; other site
502801010369	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801010370	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801010371	TM-ABC transporter signature motif; other site
502801010372	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801010373	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801010374	Walker A/P-loop; other site
502801010375	ATP binding site [chemical binding]; other site
502801010376	Q-loop/lid; other site
502801010377	ABC transporter signature motif; other site
502801010378	Walker B; other site
502801010379	D-loop; other site
502801010380	H-loop/switch region; other site
502801010381	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801010382	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
502801010383	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_9; cd06318
502801010384	putative ligand binding site [chemical binding]; other site
502801010385	ornithine decarboxylase; Provisional; Region: PRK13578
502801010386	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
502801010387	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
502801010388	homodimer interface [polypeptide binding]; other site
502801010389	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801010390	catalytic residue [active]
502801010391	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
502801010392	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
502801010393	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
502801010394	Transposase and inactivated derivatives, IS1 family [DNA replication, recombination, and repair]; Region: InsB; COG1662
502801010395	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
502801010396	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
502801010397	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
502801010398	Peptidase family M23; Region: Peptidase_M23; pfam01551
502801010399	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
502801010400	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
502801010401	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
502801010402	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
502801010403	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
502801010404	Peptidase family M23; Region: Peptidase_M23; pfam01551
502801010405	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
502801010406	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
502801010407	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
502801010408	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
502801010409	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
502801010410	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
502801010411	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
502801010412	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801010413	Walker A motif; other site
502801010414	ATP binding site [chemical binding]; other site
502801010415	Walker B motif; other site
502801010416	arginine finger; other site
502801010417	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801010418	Walker A motif; other site
502801010419	ATP binding site [chemical binding]; other site
502801010420	Walker B motif; other site
502801010421	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
502801010422	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
502801010423	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
502801010424	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
502801010425	ligand binding site [chemical binding]; other site
502801010426	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
502801010427	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
502801010428	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
502801010429	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
502801010430	Protein of unknown function (DUF877); Region: DUF877; pfam05943
502801010431	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
502801010432	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
502801010433	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
502801010434	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
502801010435	CAAX protease self-immunity; Region: Abi; pfam02517
502801010436	Autoinducer synthetase; Region: Autoind_synth; pfam00765
502801010437	Autoinducer binding domain; Region: Autoind_bind; pfam03472
502801010438	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801010439	DNA binding residues [nucleotide binding]
502801010440	dimerization interface [polypeptide binding]; other site
502801010441	Predicted peptidase [General function prediction only]; Region: COG4099
502801010442	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
502801010443	Protocatechuate 3,4-dioxygenase beta subunit [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PcaH; COG3485
502801010444	Intradiol dioxygenase supgroup. Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. They break the catechol C1-C2 bond and utilize Fe3+, as opposed to  the...; Region: intradiol_dioxygenase_like; cd03457
502801010445	putative active site [active]
502801010446	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801010447	Major Facilitator Superfamily; Region: MFS_1; pfam07690
502801010448	putative substrate translocation pore; other site
502801010449	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
502801010450	IucA / IucC family; Region: IucA_IucC; pfam04183
502801010451	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
502801010452	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
502801010453	Siderophore biosynthesis protein domain; Region: AlcB; smart01006
502801010454	Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: RhbC; COG4264
502801010455	IucA / IucC family; Region: IucA_IucC; pfam04183
502801010456	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
502801010457	Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: IucD; COG3486
502801010458	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
502801010459	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
502801010460	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801010461	N-terminal plug; other site
502801010462	ligand-binding site [chemical binding]; other site
502801010463	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
502801010464	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
502801010465	Sugar-binding cellulase-like; Region: Cellulase-like; pfam12876
502801010466	Transcriptional regulators [Transcription]; Region: PurR; COG1609
502801010467	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801010468	DNA binding site [nucleotide binding]
502801010469	domain linker motif; other site
502801010470	Ligand-binding domain of DNA-binding regulatory proteins specific to sucrose that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_sucrose_transcription_regulator; cd06288
502801010471	putative dimerization interface [polypeptide binding]; other site
502801010472	putative ligand binding site [chemical binding]; other site
502801010473	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
502801010474	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
502801010475	transmembrane helices; other site
502801010476	hypothetical protein; Provisional; Region: PRK10039
502801010477	HEAT repeats; Region: HEAT_2; pfam13646
502801010478	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
502801010479	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
502801010480	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
502801010481	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
502801010482	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
502801010483	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
502801010484	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
502801010485	RHS Repeat; Region: RHS_repeat; cl11982
502801010486	RHS Repeat; Region: RHS_repeat; pfam05593
502801010487	RHS Repeat; Region: RHS_repeat; cl11982
502801010488	RHS protein; Region: RHS; pfam03527
502801010489	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
502801010490	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
502801010491	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
502801010492	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
502801010493	Gp5 C-terminal repeat (3 copies); Region: Gp5_C; pfam06715
502801010494	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
502801010495	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
502801010496	Autotransporter beta-domain; Region: Autotransporter; smart00869
502801010497	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
502801010498	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
502801010499	Autotransporter beta-domain; Region: Autotransporter; smart00869
502801010500	fructuronate transporter; Provisional; Region: PRK10034
502801010501	gluconate transporter; Region: gntP; TIGR00791
502801010502	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
502801010503	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801010504	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801010505	Walker A/P-loop; other site
502801010506	ATP binding site [chemical binding]; other site
502801010507	Q-loop/lid; other site
502801010508	ABC transporter signature motif; other site
502801010509	Walker B; other site
502801010510	D-loop; other site
502801010511	H-loop/switch region; other site
502801010512	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
502801010513	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
502801010514	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801010515	Walker A/P-loop; other site
502801010516	ATP binding site [chemical binding]; other site
502801010517	Q-loop/lid; other site
502801010518	ABC transporter signature motif; other site
502801010519	Walker B; other site
502801010520	D-loop; other site
502801010521	H-loop/switch region; other site
502801010522	siderophore transporter, RhtX/FptX family; Region: sider_RhtX_FptX; TIGR02718
502801010523	muropeptide transporter; Validated; Region: ampG; cl17669
502801010524	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
502801010525	Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PchG; COG4693
502801010526	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
502801010527	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
502801010528	Condensation domain; Region: Condensation; pfam00668
502801010529	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
502801010530	Nonribosomal peptide synthase; Region: NRPS; pfam08415
502801010531	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
502801010532	acyl-activating enzyme (AAE) consensus motif; other site
502801010533	AMP binding site [chemical binding]; other site
502801010534	Methyltransferase domain; Region: Methyltransf_31; pfam13847
502801010535	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801010536	S-adenosylmethionine binding site [chemical binding]; other site
502801010537	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
502801010538	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
502801010539	Thioesterase domain; Region: Thioesterase; pfam00975
502801010540	acyl-CoA synthetase; Validated; Region: PRK05850
502801010541	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
502801010542	acyl-activating enzyme (AAE) consensus motif; other site
502801010543	active site
502801010544	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
502801010545	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
502801010546	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
502801010547	active site
502801010548	Condensation domain; Region: Condensation; pfam00668
502801010549	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
502801010550	Nonribosomal peptide synthase; Region: NRPS; pfam08415
502801010551	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
502801010552	acyl-activating enzyme (AAE) consensus motif; other site
502801010553	AMP binding site [chemical binding]; other site
502801010554	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
502801010555	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
502801010556	Condensation domain; Region: Condensation; pfam00668
502801010557	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
502801010558	Nonribosomal peptide synthase; Region: NRPS; pfam08415
502801010559	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
502801010560	acyl-activating enzyme (AAE) consensus motif; other site
502801010561	AMP binding site [chemical binding]; other site
502801010562	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
502801010563	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
502801010564	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801010565	N-terminal plug; other site
502801010566	ligand-binding site [chemical binding]; other site
502801010567	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
502801010568	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
502801010569	metal binding site [ion binding]; metal-binding site
502801010570	dimer interface [polypeptide binding]; other site
502801010571	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
502801010572	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
502801010573	E3 ubiquitin-protein ligase SlrP; Provisional; Region: PRK15370
502801010574	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
502801010575	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
502801010576	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
502801010577	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
502801010578	Autotransporter beta-domain; Region: Autotransporter; pfam03797
502801010579	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
502801010580	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
502801010581	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
502801010582	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801010583	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801010584	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3322
502801010585	PAS domain S-box; Region: sensory_box; TIGR00229
502801010586	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
502801010587	putative active site [active]
502801010588	heme pocket [chemical binding]; other site
502801010589	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
502801010590	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
502801010591	metal binding site [ion binding]; metal-binding site
502801010592	active site
502801010593	I-site; other site
502801010594	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
502801010595	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
502801010596	Helix-turn-helix domain; Region: HTH_28; pfam13518
502801010597	Helix-turn-helix domain; Region: HTH_28; pfam13518
502801010598	putative transposase OrfB; Reviewed; Region: PHA02517
502801010599	HTH-like domain; Region: HTH_21; pfam13276
502801010600	Integrase core domain; Region: rve; pfam00665
502801010601	Integrase core domain; Region: rve_2; pfam13333
502801010602	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
502801010603	Protein of unknown function (DUF805); Region: DUF805; pfam05656
502801010604	hypothetical protein; Validated; Region: PRK06778
502801010605	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
502801010606	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
502801010607	ligand binding site [chemical binding]; other site
502801010608	flagellar motor protein MotA; Provisional; Region: PRK12482
502801010609	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
502801010610	flagellar biosynthesis sigma factor; Provisional; Region: PRK12427
502801010611	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
502801010612	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
502801010613	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
502801010614	DNA binding residues [nucleotide binding]
502801010615	Flagellar basal body-associated protein FliL; Region: FliL; pfam03748
502801010616	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
502801010617	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
502801010618	Flagellin-specific chaperone FliS [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliS; COG1516
502801010619	Flagellar capping protein [Cell motility and secretion]; Region: FliD; COG1345
502801010620	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
502801010621	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
502801010622	Flagellin and related hook-associated proteins [Cell motility and secretion]; Region: FlgL; COG1344
502801010623	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
502801010624	Flagellin and related hook-associated proteins [Cell motility and secretion]; Region: FlgL; COG1344
502801010625	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
502801010626	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
502801010627	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801010628	DNA binding site [nucleotide binding]
502801010629	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK07192
502801010630	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
502801010631	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07191
502801010632	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
502801010633	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
502801010634	peptidoglycan hydrolase; Reviewed; Region: flgJ; PRK12708
502801010635	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
502801010636	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
502801010637	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK12407
502801010638	Flagellar L-ring protein; Region: FlgH; pfam02107
502801010639	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
502801010640	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
502801010641	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
502801010642	flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640
502801010643	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
502801010644	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
502801010645	flagellar hook protein FlgE; Validated; Region: flgE; PRK06803
502801010646	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
502801010647	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
502801010648	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
502801010649	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
502801010650	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK09619
502801010651	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
502801010652	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
502801010653	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK06802
502801010654	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
502801010655	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
502801010656	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK12685
502801010657	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
502801010658	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
502801010659	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
502801010660	flagellar biosynthesis anti-sigma factor FlgM; Region: FlgM_jcvi; TIGR03824
502801010661	FlgN protein; Region: FlgN; pfam05130
502801010662	flagellar export protein FliJ; Region: flagell_FliJ; TIGR02473
502801010663	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07196
502801010664	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
502801010665	Walker A motif; other site
502801010666	ATP binding site [chemical binding]; other site
502801010667	Walker B motif; other site
502801010668	flagellar assembly protein H; Provisional; Region: fliH; PRK13386
502801010669	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
502801010670	Flagellar assembly protein FliH; Region: FliH; pfam02108
502801010671	flagellar motor switch protein G; Reviewed; Region: fliG; PRK07194
502801010672	MgtE intracellular N domain; Region: MgtE_N; smart00924
502801010673	FliG C-terminal domain; Region: FliG_C; pfam01706
502801010674	flagellar MS-ring protein; Reviewed; Region: fliF; PRK07193
502801010675	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
502801010676	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
502801010677	Flagellar hook-basal body complex protein FliE; Region: FliE; pfam02049
502801010678	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
502801010679	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801010680	Walker A motif; other site
502801010681	ATP binding site [chemical binding]; other site
502801010682	Walker B motif; other site
502801010683	arginine finger; other site
502801010684	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
502801010685	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
502801010686	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
502801010687	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
502801010688	Flagellar biosynthesis pathway, component FliQ [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliQ; COG1987
502801010689	Flagellar biosynthesis pathway, component FliR [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliR; COG1684
502801010690	Flagellar biosynthesis pathway, component FlhB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhB; COG1377
502801010691	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
502801010692	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
502801010693	FHIPEP family; Region: FHIPEP; pfam00771
502801010694	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
502801010695	Uncharacterized protein conserved in bacteria, putative lipoprotein [Function unknown]; Region: LprI; COG4461
502801010696	ABC-type Fe2+-enterobactin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG4592
502801010697	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
502801010698	siderophore binding site; other site
502801010699	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
502801010700	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
502801010701	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801010702	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
502801010703	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
502801010704	PapC N-terminal domain; Region: PapC_N; pfam13954
502801010705	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
502801010706	PapC C-terminal domain; Region: PapC_C; pfam13953
502801010707	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
502801010708	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
502801010709	Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704
502801010710	active site
502801010711	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
502801010712	Interdomain contacts; other site
502801010713	Cytokine receptor motif; other site
502801010714	chitin-binding domain of Chi A1-like proteins; Region: ChiA1_BD; cd12214
502801010715	Chitin binding domain; Region: Chitin_bind_3; pfam03067
502801010716	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
502801010717	Interdomain contacts; other site
502801010718	Cytokine receptor motif; other site
502801010719	Uncharacterized protein contain chitin-binding domain type 3 [General function prediction only]; Region: COG3979
502801010720	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
502801010721	Interdomain contacts; other site
502801010722	Cytokine receptor motif; other site
502801010723	Chitin/cellulose binding domains of chitinase and related enzymes; Region: ChtBD3; cl00046
502801010724	aromatic chitin/cellulose binding site residues [chemical binding]; other site
502801010725	DDE domain; Region: DDE_Tnp_IS240; pfam13610
502801010726	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355
502801010727	Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960
502801010728	Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629
502801010729	Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion]; Region: CpaC; COG4964
502801010730	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
502801010731	Flp pilus assembly protein, ATPase CpaE [Intracellular trafficking and secretion]; Region: CpaE; COG4963
502801010732	This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111
502801010733	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
502801010734	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
502801010735	ATP binding site [chemical binding]; other site
502801010736	Walker A motif; other site
502801010737	hexamer interface [polypeptide binding]; other site
502801010738	Walker B motif; other site
502801010739	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
502801010740	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
502801010741	Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064
502801010742	Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking and secretion]; Region: TadD; COG5010
502801010743	Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking and secretion]; Region: TadD; COG5010
502801010744	Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961
502801010745	Putative Flp pilus-assembly TadE/G-like; Region: Tad; pfam13400
502801010746	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
502801010747	metal ion-dependent adhesion site (MIDAS); other site
502801010748	biopolymer transport protein ExbD; Provisional; Region: PRK11267
502801010749	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
502801010750	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
502801010751	cystathionine beta-lyase; Provisional; Region: PRK08114
502801010752	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
502801010753	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801010754	catalytic residue [active]
502801010755	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
502801010756	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
502801010757	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
502801010758	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801010759	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
502801010760	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801010761	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
502801010762	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
502801010763	dimer interface [polypeptide binding]; other site
502801010764	active site
502801010765	metal binding site [ion binding]; metal-binding site
502801010766	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
502801010767	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
502801010768	active site
502801010769	catalytic tetrad [active]
502801010770	hypothetical protein; Provisional; Region: PRK01254
502801010771	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
502801010772	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
502801010773	FtsI repressor; Provisional; Region: PRK10883
502801010774	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
502801010775	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
502801010776	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
502801010777	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
502801010778	putative acyl-acceptor binding pocket; other site
502801010779	DNA topoisomerase IV subunit A; Validated; Region: PRK05561
502801010780	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
502801010781	CAP-like domain; other site
502801010782	active site
502801010783	primary dimer interface [polypeptide binding]; other site
502801010784	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
502801010785	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801010786	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801010787	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
502801010788	dimerization interface [polypeptide binding]; other site
502801010789	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
502801010790	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801010791	ATP binding site [chemical binding]; other site
502801010792	Mg2+ binding site [ion binding]; other site
502801010793	G-X-G motif; other site
502801010794	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
502801010795	anchoring element; other site
502801010796	dimer interface [polypeptide binding]; other site
502801010797	ATP binding site [chemical binding]; other site
502801010798	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
502801010799	active site
502801010800	metal binding site [ion binding]; metal-binding site
502801010801	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
502801010802	esterase YqiA; Provisional; Region: PRK11071
502801010803	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
502801010804	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
502801010805	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
502801010806	active site
502801010807	metal binding site [ion binding]; metal-binding site
502801010808	hexamer interface [polypeptide binding]; other site
502801010809	putative dehydrogenase; Provisional; Region: PRK11039
502801010810	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
502801010811	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
502801010812	dimer interface [polypeptide binding]; other site
502801010813	ADP-ribose binding site [chemical binding]; other site
502801010814	active site
502801010815	nudix motif; other site
502801010816	metal binding site [ion binding]; metal-binding site
502801010817	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
502801010818	hypothetical protein; Provisional; Region: PRK11653
502801010819	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
502801010820	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
502801010821	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
502801010822	putative active site [active]
502801010823	metal binding site [ion binding]; metal-binding site
502801010824	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
502801010825	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
502801010826	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
502801010827	putative transporter; Provisional; Region: PRK11021
502801010828	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
502801010829	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
502801010830	putative ribose interaction site [chemical binding]; other site
502801010831	putative ADP binding site [chemical binding]; other site
502801010832	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
502801010833	active site
502801010834	nucleotide binding site [chemical binding]; other site
502801010835	HIGH motif; other site
502801010836	KMSKS motif; other site
502801010837	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
502801010838	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
502801010839	metal binding triad; other site
502801010840	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
502801010841	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
502801010842	metal binding triad; other site
502801010843	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
502801010844	Uncharacterized conserved protein [Function unknown]; Region: COG3025
502801010845	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
502801010846	putative active site [active]
502801010847	putative metal binding residues [ion binding]; other site
502801010848	signature motif; other site
502801010849	putative triphosphate binding site [ion binding]; other site
502801010850	SH3 domain-containing protein; Provisional; Region: PRK10884
502801010851	Bacterial SH3 domain homologues; Region: SH3b; smart00287
502801010852	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
502801010853	Poly A polymerase head domain; Region: PolyA_pol; pfam01743
502801010854	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
502801010855	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
502801010856	Zn2+ binding site [ion binding]; other site
502801010857	Mg2+ binding site [ion binding]; other site
502801010858	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
502801010859	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
502801010860	homooctamer interface [polypeptide binding]; other site
502801010861	active site
502801010862	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
502801010863	UGMP family protein; Validated; Region: PRK09604
502801010864	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
502801010865	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
502801010866	DNA primase; Validated; Region: dnaG; PRK05667
502801010867	CHC2 zinc finger; Region: zf-CHC2; pfam01807
502801010868	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
502801010869	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
502801010870	active site
502801010871	metal binding site [ion binding]; metal-binding site
502801010872	interdomain interaction site; other site
502801010873	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
502801010874	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
502801010875	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
502801010876	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
502801010877	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
502801010878	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
502801010879	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
502801010880	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
502801010881	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
502801010882	DNA binding residues [nucleotide binding]
502801010883	Abortive infection C-terminus; Region: Abi_C; pfam14355
502801010884	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
502801010885	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
502801010886	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
502801010887	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
502801010888	Baseplate J-like protein; Region: Baseplate_J; cl01294
502801010889	Protein of unknown function (DUF2590); Region: DUF2590; pfam10761
502801010890	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
502801010891	Protein of unknown function (DUF2765); Region: DUF2765; pfam10963
502801010892	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
502801010893	Phage holin family 2; Region: Phage_holin_2; pfam04550
502801010894	Protein of unknown function (DUF2597); Region: DUF2597; pfam10772
502801010895	Protein of unknown function (DUF2586); Region: DUF2586; pfam10758
502801010896	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
502801010897	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
502801010898	terminase endonuclease subunit; Provisional; Region: M; PHA02537
502801010899	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
502801010900	Phage major capsid protein, P2 family; Region: Phage_cap_P2; cl04947
502801010901	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
502801010902	terminase ATPase subunit; Provisional; Region: P; PHA02535
502801010903	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
502801010904	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
502801010905	Phage-related protein [Function unknown]; Region: COG4695; cl01923
502801010906	Phage portal protein; Region: Phage_portal; pfam04860
502801010907	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
502801010908	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
502801010909	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
502801010910	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
502801010911	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
502801010912	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
502801010913	integrase; Provisional; Region: int; PHA02601
502801010914	Phage HP1 integrase, C-terminal catalytic domain. Bacteriophage HP1 and related integrases are found in eubacteria, plasmids and temperate bacteriophages of the P2 family.  They belong to the DNA breaking-rejoining enzyme superfamily, which includes...; Region: HP1_INT_C; cd00797
502801010915	dimer interface [polypeptide binding]; other site
502801010916	active site
502801010917	catalytic residues [active]
502801010918	Int/Topo IB signature motif; other site
502801010919	Phage terminase, small subunit [DNA replication, recombination, and repair]; Region: XtmA; COG3728
502801010920	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
502801010921	active site
502801010922	Fic/DOC family; Region: Fic; pfam02661
502801010923	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801010924	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801010925	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
502801010926	dimerization interface [polypeptide binding]; other site
502801010927	Predicted protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: COG3531
502801010928	DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025
502801010929	catalytic residues [active]
502801010930	putative monooxygenase; Provisional; Region: PRK11118
502801010931	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
502801010932	homotrimer interaction site [polypeptide binding]; other site
502801010933	putative active site [active]
502801010934	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
502801010935	homotrimer interaction site [polypeptide binding]; other site
502801010936	putative active site [active]
502801010937	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
502801010938	YheO-like PAS domain; Region: PAS_6; pfam08348
502801010939	HTH domain; Region: HTH_22; pfam13309
502801010940	Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins; Region: PYR_PYL_RCAR_like; cd07821
502801010941	putative hydrophobic ligand binding site [chemical binding]; other site
502801010942	protein interface [polypeptide binding]; other site
502801010943	gate; other site
502801010944	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
502801010945	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
502801010946	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801010947	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801010948	homodimer interface [polypeptide binding]; other site
502801010949	catalytic residue [active]
502801010950	multidrug resistance protein MdtN; Provisional; Region: PRK10476
502801010951	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801010952	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801010953	Predicted membrane protein [Function unknown]; Region: COG1289
502801010954	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
502801010955	Outer membrane efflux protein; Region: OEP; pfam02321
502801010956	Outer membrane efflux protein; Region: OEP; pfam02321
502801010957	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
502801010958	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
502801010959	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
502801010960	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
502801010961	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801010962	dimer interface [polypeptide binding]; other site
502801010963	conserved gate region; other site
502801010964	putative PBP binding loops; other site
502801010965	ABC-ATPase subunit interface; other site
502801010966	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801010967	dimer interface [polypeptide binding]; other site
502801010968	conserved gate region; other site
502801010969	putative PBP binding loops; other site
502801010970	ABC-ATPase subunit interface; other site
502801010971	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
502801010972	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
502801010973	Transcriptional regulators [Transcription]; Region: PurR; COG1609
502801010974	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801010975	DNA binding site [nucleotide binding]
502801010976	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
502801010977	ligand binding site [chemical binding]; other site
502801010978	dimerization interface [polypeptide binding]; other site
502801010979	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
502801010980	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
502801010981	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
502801010982	Walker A/P-loop; other site
502801010983	ATP binding site [chemical binding]; other site
502801010984	Q-loop/lid; other site
502801010985	ABC transporter signature motif; other site
502801010986	Walker B; other site
502801010987	D-loop; other site
502801010988	H-loop/switch region; other site
502801010989	TOBE domain; Region: TOBE_2; pfam08402
502801010990	Putative glucoamylase; Region: Glycoamylase; pfam10091
502801010991	Autotransporter beta-domain; Region: Autotransporter; smart00869
502801010992	flavocytochrome c; Region: flavo_cyto_c; TIGR01813
502801010993	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
502801010994	Protein of unknown function (DUF1436); Region: DUF1436; pfam07262
502801010995	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801010996	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801010997	CRISPR type II-A/NMEMI-associated protein Csn2; Region: cas_Csn2; TIGR01866
502801010998	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801010999	Pre-toxin domain with VENN motif; Region: PT-VENN; pfam04829
502801011000	haemagglutination activity domain; Region: Haemagg_act; pfam05860
502801011001	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
502801011002	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801011003	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801011004	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801011005	CRISPR type II-A/NMEMI-associated protein Csn2; Region: cas_Csn2; TIGR01866
502801011006	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
502801011007	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
502801011008	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
502801011009	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
502801011010	metal ion-dependent adhesion site (MIDAS); other site
502801011011	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
502801011012	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
502801011013	putative metal binding site [ion binding]; other site
502801011014	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
502801011015	metal ion-dependent adhesion site (MIDAS); other site
502801011016	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
502801011017	metal ion-dependent adhesion site (MIDAS); other site
502801011018	Protein phosphatase 2C; Region: PP2C_2; pfam13672
502801011019	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
502801011020	substrate binding site [chemical binding]; other site
502801011021	activation loop (A-loop); other site
502801011022	acid-resistance membrane protein; Provisional; Region: PRK10209
502801011023	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
502801011024	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
502801011025	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
502801011026	active site
502801011027	FMN binding site [chemical binding]; other site
502801011028	2,4-decadienoyl-CoA binding site; other site
502801011029	catalytic residue [active]
502801011030	4Fe-4S cluster binding site [ion binding]; other site
502801011031	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
502801011032	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
502801011033	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801011034	S-adenosylmethionine binding site [chemical binding]; other site
502801011035	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
502801011036	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
502801011037	Autotransporter beta-domain; Region: Autotransporter; pfam03797
502801011038	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
502801011039	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
502801011040	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
502801011041	serine/threonine transporter SstT; Provisional; Region: PRK13628
502801011042	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
502801011043	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
502801011044	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
502801011045	galactarate dehydratase; Region: galactar-dH20; TIGR03248
502801011046	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
502801011047	altronate oxidoreductase; Provisional; Region: PRK03643
502801011048	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
502801011049	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
502801011050	Glucuronate isomerase; Region: UxaC; pfam02614
502801011051	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
502801011052	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801011053	D-galactonate transporter; Region: 2A0114; TIGR00893
502801011054	putative substrate translocation pore; other site
502801011055	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
502801011056	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801011057	DNA-binding site [nucleotide binding]; DNA binding site
502801011058	FCD domain; Region: FCD; pfam07729
502801011059	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
502801011060	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
502801011061	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
502801011062	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
502801011063	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
502801011064	Predicted membrane protein [Function unknown]; Region: COG5393
502801011065	YqjK-like protein; Region: YqjK; pfam13997
502801011066	Predicted membrane protein [Function unknown]; Region: COG2259
502801011067	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
502801011068	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
502801011069	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
502801011070	putative dimer interface [polypeptide binding]; other site
502801011071	N-terminal domain interface [polypeptide binding]; other site
502801011072	putative substrate binding pocket (H-site) [chemical binding]; other site
502801011073	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801011074	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
502801011075	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
502801011076	dimerization interface [polypeptide binding]; other site
502801011077	Pirin-related protein [General function prediction only]; Region: COG1741
502801011078	Pirin; Region: Pirin; pfam02678
502801011079	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
502801011080	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
502801011081	putative SAM binding site [chemical binding]; other site
502801011082	putative homodimer interface [polypeptide binding]; other site
502801011083	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
502801011084	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
502801011085	putative ligand binding site [chemical binding]; other site
502801011086	hypothetical protein; Reviewed; Region: PRK12497
502801011087	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
502801011088	dimer interface [polypeptide binding]; other site
502801011089	active site
502801011090	outer membrane lipoprotein; Provisional; Region: PRK11023
502801011091	BON domain; Region: BON; pfam04972
502801011092	BON domain; Region: BON; cl02771
502801011093	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
502801011094	Transglycosylase; Region: Transgly; cl17702
502801011095	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
502801011096	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
502801011097	conserved cys residue [active]
502801011098	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
502801011099	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
502801011100	putative active site [active]
502801011101	heme pocket [chemical binding]; other site
502801011102	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801011103	dimer interface [polypeptide binding]; other site
502801011104	phosphorylation site [posttranslational modification]
502801011105	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801011106	ATP binding site [chemical binding]; other site
502801011107	Mg2+ binding site [ion binding]; other site
502801011108	G-X-G motif; other site
502801011109	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801011110	active site
502801011111	phosphorylation site [posttranslational modification]
502801011112	intermolecular recognition site; other site
502801011113	dimerization interface [polypeptide binding]; other site
502801011114	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
502801011115	putative binding surface; other site
502801011116	active site
502801011117	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
502801011118	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
502801011119	FeS/SAM binding site; other site
502801011120	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
502801011121	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
502801011122	active site
502801011123	dimer interface [polypeptide binding]; other site
502801011124	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
502801011125	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
502801011126	active site
502801011127	FMN binding site [chemical binding]; other site
502801011128	substrate binding site [chemical binding]; other site
502801011129	3Fe-4S cluster binding site [ion binding]; other site
502801011130	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
502801011131	domain interface; other site
502801011132	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
502801011133	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
502801011134	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
502801011135	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
502801011136	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
502801011137	stringent starvation protein A; Provisional; Region: sspA; PRK09481
502801011138	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
502801011139	C-terminal domain interface [polypeptide binding]; other site
502801011140	putative GSH binding site (G-site) [chemical binding]; other site
502801011141	dimer interface [polypeptide binding]; other site
502801011142	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
502801011143	dimer interface [polypeptide binding]; other site
502801011144	N-terminal domain interface [polypeptide binding]; other site
502801011145	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
502801011146	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
502801011147	23S rRNA interface [nucleotide binding]; other site
502801011148	L3 interface [polypeptide binding]; other site
502801011149	Predicted ATPase [General function prediction only]; Region: COG1485
502801011150	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
502801011151	hypothetical protein; Provisional; Region: PRK11677
502801011152	serine endoprotease; Provisional; Region: PRK10139
502801011153	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
502801011154	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
502801011155	protein binding site [polypeptide binding]; other site
502801011156	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
502801011157	serine endoprotease; Provisional; Region: PRK10898
502801011158	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
502801011159	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
502801011160	protein binding site [polypeptide binding]; other site
502801011161	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
502801011162	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
502801011163	hinge; other site
502801011164	active site
502801011165	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
502801011166	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
502801011167	anti sigma factor interaction site; other site
502801011168	regulatory phosphorylation site [posttranslational modification]; other site
502801011169	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
502801011170	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
502801011171	mce related protein; Region: MCE; pfam02470
502801011172	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
502801011173	conserved hypothetical integral membrane protein; Region: TIGR00056
502801011174	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
502801011175	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
502801011176	Walker A/P-loop; other site
502801011177	ATP binding site [chemical binding]; other site
502801011178	Q-loop/lid; other site
502801011179	ABC transporter signature motif; other site
502801011180	Walker B; other site
502801011181	D-loop; other site
502801011182	H-loop/switch region; other site
502801011183	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
502801011184	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
502801011185	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
502801011186	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
502801011187	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
502801011188	putative active site [active]
502801011189	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
502801011190	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
502801011191	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
502801011192	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
502801011193	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
502801011194	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
502801011195	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
502801011196	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
502801011197	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
502801011198	Walker A/P-loop; other site
502801011199	ATP binding site [chemical binding]; other site
502801011200	Q-loop/lid; other site
502801011201	ABC transporter signature motif; other site
502801011202	Walker B; other site
502801011203	D-loop; other site
502801011204	H-loop/switch region; other site
502801011205	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
502801011206	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
502801011207	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
502801011208	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
502801011209	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
502801011210	30S subunit binding site; other site
502801011211	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
502801011212	active site
502801011213	phosphorylation site [posttranslational modification]
502801011214	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
502801011215	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
502801011216	dimerization domain swap beta strand [polypeptide binding]; other site
502801011217	regulatory protein interface [polypeptide binding]; other site
502801011218	active site
502801011219	regulatory phosphorylation site [posttranslational modification]; other site
502801011220	Aspartate carbamoyltransferase, catalytic chain [Nucleotide transport and metabolism]; Region: PyrB; COG0540
502801011221	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
502801011222	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
502801011223	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
502801011224	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
502801011225	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
502801011226	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
502801011227	homotrimer interaction site [polypeptide binding]; other site
502801011228	putative active site [active]
502801011229	Periplasmic lysozyme inhibitor, I-type (PliI) and similar proteins; Region: PliI_like; cd09632
502801011230	dimer interface [polypeptide binding]; other site
502801011231	putative inhibitory loop; other site
502801011232	trehalose repressor; Provisional; Region: treR; PRK09492
502801011233	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801011234	DNA binding site [nucleotide binding]
502801011235	domain linker motif; other site
502801011236	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
502801011237	dimerization interface [polypeptide binding]; other site
502801011238	ligand binding site [chemical binding]; other site
502801011239	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
502801011240	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
502801011241	active site turn [active]
502801011242	phosphorylation site [posttranslational modification]
502801011243	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
502801011244	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
502801011245	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
502801011246	Ca binding site [ion binding]; other site
502801011247	active site
502801011248	catalytic site [active]
502801011249	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
502801011250	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
502801011251	Soluble cytochrome b562 [Energy production and conversion]; Region: CybC; COG3783
502801011252	peptidase PmbA; Provisional; Region: PRK11040
502801011253	hypothetical protein; Provisional; Region: PRK05255
502801011254	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
502801011255	RNAase interaction site [polypeptide binding]; other site
502801011256	Barnase, a member of the family of homologous microbial ribonucleases, catalyses the cleavage of single-stranded RNA via a two-step mechanism thought to be similar to that of pancreatic ribonuclease. The mechanism involves a transesterification to give a...; Region: barnase; cd00933
502801011257	active site
502801011258	succinic semialdehyde dehydrogenase; Region: PLN02278
502801011259	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
502801011260	tetramerization interface [polypeptide binding]; other site
502801011261	NAD(P) binding site [chemical binding]; other site
502801011262	catalytic residues [active]
502801011263	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
502801011264	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
502801011265	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
502801011266	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
502801011267	HlyD family secretion protein; Region: HlyD_3; pfam13437
502801011268	efflux system membrane protein; Provisional; Region: PRK11594
502801011269	transcriptional regulator; Provisional; Region: PRK10632
502801011270	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801011271	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
502801011272	putative effector binding pocket; other site
502801011273	dimerization interface [polypeptide binding]; other site
502801011274	Transcriptional regulator [Transcription]; Region: LysR; COG0583
502801011275	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
502801011276	Salmonella virulence plasmid 28.1kDa A protein; Region: VRP1; pfam03538
502801011277	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
502801011278	Family description; Region: VCBS; pfam13517
502801011279	Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256
502801011280	Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255
502801011281	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
502801011282	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
502801011283	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
502801011284	protease TldD; Provisional; Region: tldD; PRK10735
502801011285	nitrilase; Region: PLN02798
502801011286	Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572
502801011287	putative active site [active]
502801011288	catalytic triad [active]
502801011289	dimer interface [polypeptide binding]; other site
502801011290	hypothetical protein; Provisional; Region: PRK10899
502801011291	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
502801011292	ribonuclease G; Provisional; Region: PRK11712
502801011293	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
502801011294	homodimer interface [polypeptide binding]; other site
502801011295	oligonucleotide binding site [chemical binding]; other site
502801011296	Maf-like protein; Region: Maf; pfam02545
502801011297	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
502801011298	active site
502801011299	dimer interface [polypeptide binding]; other site
502801011300	rod shape-determining protein MreD; Provisional; Region: PRK11060
502801011301	rod shape-determining protein MreC; Region: mreC; TIGR00219
502801011302	rod shape-determining protein MreC; Region: MreC; pfam04085
502801011303	rod shape-determining protein MreB; Provisional; Region: PRK13927
502801011304	MreB and similar proteins; Region: MreB_like; cd10225
502801011305	nucleotide binding site [chemical binding]; other site
502801011306	Mg binding site [ion binding]; other site
502801011307	putative protofilament interaction site [polypeptide binding]; other site
502801011308	RodZ interaction site [polypeptide binding]; other site
502801011309	regulatory protein CsrD; Provisional; Region: PRK11059
502801011310	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
502801011311	metal binding site [ion binding]; metal-binding site
502801011312	active site
502801011313	I-site; other site
502801011314	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
502801011315	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
502801011316	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
502801011317	NADP binding site [chemical binding]; other site
502801011318	dimer interface [polypeptide binding]; other site
502801011319	TMAO/DMSO reductase; Reviewed; Region: PRK05363
502801011320	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
502801011321	Moco binding site; other site
502801011322	metal coordination site [ion binding]; other site
502801011323	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
502801011324	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
502801011325	Dehydroquinase class II; Region: DHquinase_II; pfam01220
502801011326	active site
502801011327	trimer interface [polypeptide binding]; other site
502801011328	dimer interface [polypeptide binding]; other site
502801011329	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
502801011330	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
502801011331	carboxyltransferase (CT) interaction site; other site
502801011332	biotinylation site [posttranslational modification]; other site
502801011333	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
502801011334	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
502801011335	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
502801011336	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
502801011337	hypothetical protein; Provisional; Region: PRK10633
502801011338	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
502801011339	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
502801011340	Na binding site [ion binding]; other site
502801011341	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
502801011342	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
502801011343	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
502801011344	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
502801011345	FMN binding site [chemical binding]; other site
502801011346	active site
502801011347	catalytic residues [active]
502801011348	substrate binding site [chemical binding]; other site
502801011349	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
502801011350	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
502801011351	Transcriptional regulators [Transcription]; Region: GntR; COG1802
502801011352	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801011353	DNA-binding site [nucleotide binding]; DNA binding site
502801011354	FCD domain; Region: FCD; pfam07729
502801011355	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801011356	metabolite-proton symporter; Region: 2A0106; TIGR00883
502801011357	putative substrate translocation pore; other site
502801011358	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
502801011359	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
502801011360	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
502801011361	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
502801011362	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
502801011363	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
502801011364	DNA-binding site [nucleotide binding]; DNA binding site
502801011365	RNA-binding motif; other site
502801011366	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
502801011367	DNA-binding site [nucleotide binding]; DNA binding site
502801011368	RNA-binding motif; other site
502801011369	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
502801011370	DNA-binding site [nucleotide binding]; DNA binding site
502801011371	RNA-binding motif; other site
502801011372	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
502801011373	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4222
502801011374	putative S-transferase; Provisional; Region: PRK11752
502801011375	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
502801011376	C-terminal domain interface [polypeptide binding]; other site
502801011377	GSH binding site (G-site) [chemical binding]; other site
502801011378	dimer interface [polypeptide binding]; other site
502801011379	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
502801011380	dimer interface [polypeptide binding]; other site
502801011381	N-terminal domain interface [polypeptide binding]; other site
502801011382	active site
502801011383	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
502801011384	putative active site [active]
502801011385	Ribulose kinase [Energy production and conversion]; Region: AraB; COG1069
502801011386	Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_YpCarbK_like; cd07782
502801011387	N- and C-terminal domain interface [polypeptide binding]; other site
502801011388	active site
502801011389	MgATP binding site [chemical binding]; other site
502801011390	catalytic site [active]
502801011391	metal binding site [ion binding]; metal-binding site
502801011392	carbohydrate binding site [chemical binding]; other site
502801011393	putative homodimer interface [polypeptide binding]; other site
502801011394	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801011395	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801011396	TM-ABC transporter signature motif; other site
502801011397	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801011398	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801011399	TM-ABC transporter signature motif; other site
502801011400	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801011401	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801011402	Walker A/P-loop; other site
502801011403	ATP binding site [chemical binding]; other site
502801011404	Q-loop/lid; other site
502801011405	ABC transporter signature motif; other site
502801011406	Walker B; other site
502801011407	D-loop; other site
502801011408	H-loop/switch region; other site
502801011409	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801011410	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
502801011411	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
502801011412	ligand binding site [chemical binding]; other site
502801011413	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
502801011414	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
502801011415	putative acyl-acceptor binding pocket; other site
502801011416	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
502801011417	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
502801011418	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
502801011419	DNA-damage-inducible protein J [DNA replication, recombination, and repair]; Region: RelB; COG3077
502801011420	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
502801011421	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
502801011422	Walker A/P-loop; other site
502801011423	ATP binding site [chemical binding]; other site
502801011424	Q-loop/lid; other site
502801011425	ABC transporter signature motif; other site
502801011426	Walker B; other site
502801011427	D-loop; other site
502801011428	H-loop/switch region; other site
502801011429	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
502801011430	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801011431	dimer interface [polypeptide binding]; other site
502801011432	conserved gate region; other site
502801011433	putative PBP binding loops; other site
502801011434	ABC-ATPase subunit interface; other site
502801011435	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
502801011436	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
502801011437	active site
502801011438	dimer interface [polypeptide binding]; other site
502801011439	non-prolyl cis peptide bond; other site
502801011440	insertion regions; other site
502801011441	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801011442	substrate binding pocket [chemical binding]; other site
502801011443	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
502801011444	membrane-bound complex binding site; other site
502801011445	hinge residues; other site
502801011446	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
502801011447	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
502801011448	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
502801011449	intersubunit interface [polypeptide binding]; other site
502801011450	active site
502801011451	catalytic residue [active]
502801011452	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
502801011453	substrate binding site [chemical binding]; other site
502801011454	dimer interface [polypeptide binding]; other site
502801011455	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
502801011456	ATP binding site [chemical binding]; other site
502801011457	ABC-type ribose transport system, auxiliary component [Carbohydrate transport and metabolism]; Region: RbsD; COG1869
502801011458	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
502801011459	Helix-turn-helix domain; Region: HTH_18; pfam12833
502801011460	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801011461	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
502801011462	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
502801011463	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
502801011464	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
502801011465	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
502801011466	AP (apurinic/apyrimidinic) site pocket; other site
502801011467	DNA interaction; other site
502801011468	Metal-binding active site; metal-binding site
502801011469	Phage late control gene D protein (GPD); Region: Phage_GPD; cl15796
502801011470	PAAR motif; Region: PAAR_motif; pfam05488
502801011471	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
502801011472	RHS Repeat; Region: RHS_repeat; pfam05593
502801011473	RHS Repeat; Region: RHS_repeat; cl11982
502801011474	RHS Repeat; Region: RHS_repeat; pfam05593
502801011475	RHS Repeat; Region: RHS_repeat; pfam05593
502801011476	RHS Repeat; Region: RHS_repeat; cl11982
502801011477	RHS protein; Region: RHS; pfam03527
502801011478	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
502801011479	Uncharacterized conserved protein [Function unknown]; Region: COG5435
502801011480	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
502801011481	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
502801011482	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
502801011483	Gp5 C-terminal repeat (3 copies); Region: Gp5_C; pfam06715
502801011484	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
502801011485	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
502801011486	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
502801011487	ImpA domain protein; Region: DUF3702; pfam12486
502801011488	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
502801011489	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
502801011490	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
502801011491	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
502801011492	Protein of unknown function (DUF1020); Region: DUF1020; pfam06255
502801011493	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
502801011494	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
502801011495	type VI secretion-associated protein, VC_A0118 family; Region: VI_minor_1; TIGR03360
502801011496	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
502801011497	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
502801011498	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801011499	Walker A motif; other site
502801011500	ATP binding site [chemical binding]; other site
502801011501	Walker B motif; other site
502801011502	arginine finger; other site
502801011503	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801011504	Walker A motif; other site
502801011505	ATP binding site [chemical binding]; other site
502801011506	Walker B motif; other site
502801011507	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
502801011508	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
502801011509	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
502801011510	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
502801011511	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
502801011512	Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular    transport; Signal transduction mechanisms]; Region: COG3456
502801011513	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
502801011514	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
502801011515	type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359
502801011516	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3518
502801011517	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
502801011518	Protein of unknown function (DUF877); Region: DUF877; pfam05943
502801011519	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
502801011520	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
502801011521	maltose regulon periplasmic protein; Provisional; Region: PRK10564
502801011522	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
502801011523	trimer interface; other site
502801011524	sugar binding site [chemical binding]; other site
502801011525	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
502801011526	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
502801011527	Walker A/P-loop; other site
502801011528	ATP binding site [chemical binding]; other site
502801011529	Q-loop/lid; other site
502801011530	ABC transporter signature motif; other site
502801011531	Walker B; other site
502801011532	D-loop; other site
502801011533	H-loop/switch region; other site
502801011534	TOBE domain; Region: TOBE_2; pfam08402
502801011535	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
502801011536	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
502801011537	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
502801011538	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801011539	dimer interface [polypeptide binding]; other site
502801011540	conserved gate region; other site
502801011541	putative PBP binding loops; other site
502801011542	ABC-ATPase subunit interface; other site
502801011543	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
502801011544	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801011545	dimer interface [polypeptide binding]; other site
502801011546	conserved gate region; other site
502801011547	putative PBP binding loops; other site
502801011548	ABC-ATPase subunit interface; other site
502801011549	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
502801011550	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
502801011551	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
502801011552	active site
502801011553	dimer interface [polypeptide binding]; other site
502801011554	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
502801011555	dimer interface [polypeptide binding]; other site
502801011556	active site
502801011557	aspartate kinase III; Validated; Region: PRK09084
502801011558	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
502801011559	nucleotide binding site [chemical binding]; other site
502801011560	substrate binding site [chemical binding]; other site
502801011561	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
502801011562	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
502801011563	dimer interface [polypeptide binding]; other site
502801011564	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
502801011565	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
502801011566	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
502801011567	haemagglutination activity domain; Region: Haemagg_act; pfam05860
502801011568	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801011569	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801011570	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
502801011571	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801011572	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801011573	Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332
502801011574	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
502801011575	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
502801011576	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
502801011577	substrate binding pocket [chemical binding]; other site
502801011578	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
502801011579	B12 binding site [chemical binding]; other site
502801011580	cobalt ligand [ion binding]; other site
502801011581	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
502801011582	transcriptional repressor IclR; Provisional; Region: PRK11569
502801011583	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
502801011584	Bacterial transcriptional regulator; Region: IclR; pfam01614
502801011585	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
502801011586	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
502801011587	isocitrate lyase; Provisional; Region: PRK15063
502801011588	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
502801011589	tetramer interface [polypeptide binding]; other site
502801011590	active site
502801011591	Mg2+/Mn2+ binding site [ion binding]; other site
502801011592	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
502801011593	malate synthase A; Region: malate_syn_A; TIGR01344
502801011594	active site
502801011595	homoserine O-succinyltransferase; Provisional; Region: PRK05368
502801011596	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
502801011597	proposed active site lysine [active]
502801011598	conserved cys residue [active]
502801011599	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
502801011600	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
502801011601	trimer interface [polypeptide binding]; other site
502801011602	putative metal binding site [ion binding]; other site
502801011603	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
502801011604	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
502801011605	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
502801011606	shikimate binding site; other site
502801011607	NAD(P) binding site [chemical binding]; other site
502801011608	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
502801011609	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
502801011610	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
502801011611	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
502801011612	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
502801011613	hypothetical protein; Validated; Region: PRK03430
502801011614	hypothetical protein; Provisional; Region: PRK10736
502801011615	DNA protecting protein DprA; Region: dprA; TIGR00732
502801011616	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
502801011617	active site
502801011618	catalytic residues [active]
502801011619	metal binding site [ion binding]; metal-binding site
502801011620	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
502801011621	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
502801011622	putative active site [active]
502801011623	substrate binding site [chemical binding]; other site
502801011624	putative cosubstrate binding site; other site
502801011625	catalytic site [active]
502801011626	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
502801011627	substrate binding site [chemical binding]; other site
502801011628	16S rRNA methyltransferase B; Provisional; Region: PRK10901
502801011629	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
502801011630	putative RNA binding site [nucleotide binding]; other site
502801011631	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801011632	S-adenosylmethionine binding site [chemical binding]; other site
502801011633	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
502801011634	TrkA-N domain; Region: TrkA_N; pfam02254
502801011635	TrkA-C domain; Region: TrkA_C; pfam02080
502801011636	TrkA-N domain; Region: TrkA_N; pfam02254
502801011637	TrkA-C domain; Region: TrkA_C; pfam02080
502801011638	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
502801011639	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
502801011640	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
502801011641	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
502801011642	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
502801011643	DNA binding residues [nucleotide binding]
502801011644	dimer interface [polypeptide binding]; other site
502801011645	metal binding site [ion binding]; metal-binding site
502801011646	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
502801011647	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
502801011648	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
502801011649	alphaNTD homodimer interface [polypeptide binding]; other site
502801011650	alphaNTD - beta interaction site [polypeptide binding]; other site
502801011651	alphaNTD - beta' interaction site [polypeptide binding]; other site
502801011652	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
502801011653	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
502801011654	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
502801011655	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
502801011656	RNA binding surface [nucleotide binding]; other site
502801011657	30S ribosomal protein S11; Validated; Region: PRK05309
502801011658	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
502801011659	30S ribosomal protein S13; Region: bact_S13; TIGR03631
502801011660	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
502801011661	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
502801011662	SecY translocase; Region: SecY; pfam00344
502801011663	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
502801011664	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
502801011665	23S rRNA binding site [nucleotide binding]; other site
502801011666	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
502801011667	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
502801011668	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
502801011669	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
502801011670	5S rRNA interface [nucleotide binding]; other site
502801011671	23S rRNA interface [nucleotide binding]; other site
502801011672	L5 interface [polypeptide binding]; other site
502801011673	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
502801011674	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
502801011675	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
502801011676	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
502801011677	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
502801011678	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
502801011679	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
502801011680	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
502801011681	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
502801011682	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
502801011683	RNA binding site [nucleotide binding]; other site
502801011684	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
502801011685	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
502801011686	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
502801011687	23S rRNA interface [nucleotide binding]; other site
502801011688	putative translocon interaction site; other site
502801011689	signal recognition particle (SRP54) interaction site; other site
502801011690	L23 interface [polypeptide binding]; other site
502801011691	trigger factor interaction site; other site
502801011692	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
502801011693	23S rRNA interface [nucleotide binding]; other site
502801011694	5S rRNA interface [nucleotide binding]; other site
502801011695	putative antibiotic binding site [chemical binding]; other site
502801011696	L25 interface [polypeptide binding]; other site
502801011697	L27 interface [polypeptide binding]; other site
502801011698	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
502801011699	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
502801011700	G-X-X-G motif; other site
502801011701	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
502801011702	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
502801011703	protein-rRNA interface [nucleotide binding]; other site
502801011704	putative translocon binding site; other site
502801011705	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
502801011706	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
502801011707	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
502801011708	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
502801011709	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
502801011710	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
502801011711	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
502801011712	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
502801011713	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
502801011714	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
502801011715	heme binding site [chemical binding]; other site
502801011716	ferroxidase pore; other site
502801011717	ferroxidase diiron center [ion binding]; other site
502801011718	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
502801011719	elongation factor Tu; Reviewed; Region: PRK00049
502801011720	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
502801011721	G1 box; other site
502801011722	GEF interaction site [polypeptide binding]; other site
502801011723	GTP/Mg2+ binding site [chemical binding]; other site
502801011724	Switch I region; other site
502801011725	G2 box; other site
502801011726	G3 box; other site
502801011727	Switch II region; other site
502801011728	G4 box; other site
502801011729	G5 box; other site
502801011730	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
502801011731	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
502801011732	Antibiotic Binding Site [chemical binding]; other site
502801011733	elongation factor G; Reviewed; Region: PRK00007
502801011734	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
502801011735	G1 box; other site
502801011736	putative GEF interaction site [polypeptide binding]; other site
502801011737	GTP/Mg2+ binding site [chemical binding]; other site
502801011738	Switch I region; other site
502801011739	G2 box; other site
502801011740	G3 box; other site
502801011741	Switch II region; other site
502801011742	G4 box; other site
502801011743	G5 box; other site
502801011744	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
502801011745	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
502801011746	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
502801011747	30S ribosomal protein S7; Validated; Region: PRK05302
502801011748	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
502801011749	S17 interaction site [polypeptide binding]; other site
502801011750	S8 interaction site; other site
502801011751	16S rRNA interaction site [nucleotide binding]; other site
502801011752	streptomycin interaction site [chemical binding]; other site
502801011753	23S rRNA interaction site [nucleotide binding]; other site
502801011754	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
502801011755	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
502801011756	sulfur relay protein TusC; Validated; Region: PRK00211
502801011757	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
502801011758	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
502801011759	YheO-like PAS domain; Region: PAS_6; pfam08348
502801011760	HTH domain; Region: HTH_22; pfam13309
502801011761	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
502801011762	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
502801011763	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
502801011764	phi X174 lysis protein; Provisional; Region: PRK02793
502801011765	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10737
502801011766	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
502801011767	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
502801011768	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
502801011769	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
502801011770	TrkA-N domain; Region: TrkA_N; pfam02254
502801011771	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
502801011772	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
502801011773	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801011774	Walker A/P-loop; other site
502801011775	ATP binding site [chemical binding]; other site
502801011776	Q-loop/lid; other site
502801011777	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
502801011778	ABC transporter signature motif; other site
502801011779	Walker B; other site
502801011780	D-loop; other site
502801011781	ABC transporter; Region: ABC_tran_2; pfam12848
502801011782	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
502801011783	putative glycosyl transferase; Provisional; Region: PRK10073
502801011784	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
502801011785	active site
502801011786	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
502801011787	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
502801011788	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
502801011789	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
502801011790	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
502801011791	active site
502801011792	iron coordination sites [ion binding]; other site
502801011793	substrate binding pocket [chemical binding]; other site
502801011794	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
502801011795	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801011796	dimer interface [polypeptide binding]; other site
502801011797	conserved gate region; other site
502801011798	putative PBP binding loops; other site
502801011799	ABC-ATPase subunit interface; other site
502801011800	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
502801011801	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
502801011802	Walker A/P-loop; other site
502801011803	ATP binding site [chemical binding]; other site
502801011804	Q-loop/lid; other site
502801011805	ABC transporter signature motif; other site
502801011806	Walker B; other site
502801011807	D-loop; other site
502801011808	H-loop/switch region; other site
502801011809	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
502801011810	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801011811	substrate binding pocket [chemical binding]; other site
502801011812	membrane-bound complex binding site; other site
502801011813	hinge residues; other site
502801011814	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
502801011815	putative hydrolase; Provisional; Region: PRK10985
502801011816	hypothetical protein; Provisional; Region: PRK04966
502801011817	phosphoribulokinase; Provisional; Region: PRK15453
502801011818	active site
502801011819	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
502801011820	hypothetical protein; Provisional; Region: PRK10738
502801011821	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
502801011822	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
502801011823	ligand binding site [chemical binding]; other site
502801011824	flexible hinge region; other site
502801011825	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
502801011826	putative switch regulator; other site
502801011827	non-specific DNA interactions [nucleotide binding]; other site
502801011828	DNA binding site [nucleotide binding]
502801011829	sequence specific DNA binding site [nucleotide binding]; other site
502801011830	putative cAMP binding site [chemical binding]; other site
502801011831	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
502801011832	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
502801011833	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
502801011834	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801011835	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
502801011836	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
502801011837	inhibitor-cofactor binding pocket; inhibition site
502801011838	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801011839	catalytic residue [active]
502801011840	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
502801011841	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
502801011842	glutamine binding [chemical binding]; other site
502801011843	catalytic triad [active]
502801011844	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
502801011845	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
502801011846	Walker A motif; other site
502801011847	ATP binding site [chemical binding]; other site
502801011848	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
502801011849	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
502801011850	substrate binding site [chemical binding]; other site
502801011851	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
502801011852	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
502801011853	NAD binding site [chemical binding]; other site
502801011854	sugar binding site [chemical binding]; other site
502801011855	divalent metal binding site [ion binding]; other site
502801011856	tetramer (dimer of dimers) interface [polypeptide binding]; other site
502801011857	dimer interface [polypeptide binding]; other site
502801011858	Transcriptional regulators [Transcription]; Region: PurR; COG1609
502801011859	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801011860	DNA binding site [nucleotide binding]
502801011861	domain linker motif; other site
502801011862	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
502801011863	dimerization interface (closed form) [polypeptide binding]; other site
502801011864	ligand binding site [chemical binding]; other site
502801011865	TonB-dependent copper receptor; Region: TonB-copper; TIGR01778
502801011866	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
502801011867	N-terminal plug; other site
502801011868	ligand-binding site [chemical binding]; other site
502801011869	putative transporter; Provisional; Region: PRK03699
502801011870	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801011871	putative substrate translocation pore; other site
502801011872	cytosine deaminase; Provisional; Region: PRK09230
502801011873	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
502801011874	active site
502801011875	nitrite reductase subunit NirD; Provisional; Region: PRK14989
502801011876	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
502801011877	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
502801011878	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
502801011879	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
502801011880	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
502801011881	nitrite transporter NirC; Provisional; Region: PRK11562
502801011882	siroheme synthase; Provisional; Region: cysG; PRK10637
502801011883	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
502801011884	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
502801011885	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
502801011886	active site
502801011887	SAM binding site [chemical binding]; other site
502801011888	homodimer interface [polypeptide binding]; other site
502801011889	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
502801011890	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
502801011891	active site
502801011892	HIGH motif; other site
502801011893	dimer interface [polypeptide binding]; other site
502801011894	KMSKS motif; other site
502801011895	phosphoglycolate phosphatase; Provisional; Region: PRK13222
502801011896	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
502801011897	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801011898	motif II; other site
502801011899	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
502801011900	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
502801011901	substrate binding site [chemical binding]; other site
502801011902	hexamer interface [polypeptide binding]; other site
502801011903	metal binding site [ion binding]; metal-binding site
502801011904	DNA adenine methylase; Provisional; Region: PRK10904
502801011905	hypothetical protein; Reviewed; Region: PRK11901
502801011906	cell division protein DamX; Validated; Region: PRK10905
502801011907	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
502801011908	active site
502801011909	dimer interface [polypeptide binding]; other site
502801011910	metal binding site [ion binding]; metal-binding site
502801011911	shikimate kinase; Reviewed; Region: aroK; PRK00131
502801011912	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
502801011913	ADP binding site [chemical binding]; other site
502801011914	magnesium binding site [ion binding]; other site
502801011915	putative shikimate binding site; other site
502801011916	putative outer membrane porin HofQ; Provisional; Region: hofQ; PRK13568
502801011917	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
502801011918	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
502801011919	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
502801011920	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
502801011921	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
502801011922	Competence protein A; Region: Competence_A; pfam11104
502801011923	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
502801011924	Transglycosylase; Region: Transgly; pfam00912
502801011925	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
502801011926	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
502801011927	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
502801011928	ADP-ribose binding site [chemical binding]; other site
502801011929	dimer interface [polypeptide binding]; other site
502801011930	active site
502801011931	nudix motif; other site
502801011932	metal binding site [ion binding]; metal-binding site
502801011933	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
502801011934	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
502801011935	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
502801011936	motif I; other site
502801011937	active site
502801011938	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801011939	motif II; other site
502801011940	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
502801011941	RNA binding surface [nucleotide binding]; other site
502801011942	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
502801011943	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
502801011944	dimerization interface [polypeptide binding]; other site
502801011945	domain crossover interface; other site
502801011946	redox-dependent activation switch; other site
502801011947	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
502801011948	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
502801011949	active site
502801011950	substrate-binding site [chemical binding]; other site
502801011951	metal-binding site [ion binding]
502801011952	ATP binding site [chemical binding]; other site
502801011953	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
502801011954	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801011955	dimerization interface [polypeptide binding]; other site
502801011956	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801011957	dimer interface [polypeptide binding]; other site
502801011958	phosphorylation site [posttranslational modification]
502801011959	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801011960	ATP binding site [chemical binding]; other site
502801011961	Mg2+ binding site [ion binding]; other site
502801011962	G-X-G motif; other site
502801011963	osmolarity response regulator; Provisional; Region: ompR; PRK09468
502801011964	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801011965	active site
502801011966	phosphorylation site [posttranslational modification]
502801011967	intermolecular recognition site; other site
502801011968	dimerization interface [polypeptide binding]; other site
502801011969	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801011970	DNA binding site [nucleotide binding]
502801011971	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
502801011972	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
502801011973	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
502801011974	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
502801011975	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
502801011976	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
502801011977	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
502801011978	RNA binding site [nucleotide binding]; other site
502801011979	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
502801011980	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
502801011981	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
502801011982	G1 box; other site
502801011983	GTP/Mg2+ binding site [chemical binding]; other site
502801011984	Switch I region; other site
502801011985	G2 box; other site
502801011986	G3 box; other site
502801011987	Switch II region; other site
502801011988	G4 box; other site
502801011989	G5 box; other site
502801011990	Nucleoside recognition; Region: Gate; pfam07670
502801011991	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
502801011992	Nucleoside recognition; Region: Gate; pfam07670
502801011993	FeoC like transcriptional regulator; Region: FeoC; cl17677
502801011994	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
502801011995	carboxylesterase BioH; Provisional; Region: PRK10349
502801011996	DNA utilization protein GntX; Provisional; Region: PRK11595
502801011997	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
502801011998	active site
502801011999	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
502801012000	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
502801012001	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
502801012002	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
502801012003	4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640
502801012004	maltodextrin phosphorylase; Provisional; Region: PRK14985
502801012005	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
502801012006	active site pocket [active]
502801012007	transcriptional regulator MalT; Provisional; Region: PRK04841
502801012008	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801012009	DNA binding residues [nucleotide binding]
502801012010	dimerization interface [polypeptide binding]; other site
502801012011	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
502801012012	active site residue [active]
502801012013	intramembrane serine protease GlpG; Provisional; Region: PRK10907
502801012014	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
502801012015	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
502801012016	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
502801012017	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
502801012018	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
502801012019	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
502801012020	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
502801012021	glycogen phosphorylase; Provisional; Region: PRK14986
502801012022	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
502801012023	homodimer interface [polypeptide binding]; other site
502801012024	active site pocket [active]
502801012025	glycogen synthase; Provisional; Region: glgA; PRK00654
502801012026	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
502801012027	ADP-binding pocket [chemical binding]; other site
502801012028	homodimer interface [polypeptide binding]; other site
502801012029	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
502801012030	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
502801012031	ligand binding site; other site
502801012032	oligomer interface; other site
502801012033	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
502801012034	sulfate 1 binding site; other site
502801012035	glycogen debranching enzyme; Provisional; Region: PRK03705
502801012036	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
502801012037	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
502801012038	active site
502801012039	catalytic site [active]
502801012040	glycogen branching enzyme; Provisional; Region: PRK05402
502801012041	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
502801012042	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
502801012043	active site
502801012044	catalytic site [active]
502801012045	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
502801012046	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
502801012047	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
502801012048	Histidine kinase; Region: His_kinase; pfam06580
502801012049	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801012050	ATP binding site [chemical binding]; other site
502801012051	Mg2+ binding site [ion binding]; other site
502801012052	G-X-G motif; other site
502801012053	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
502801012054	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
502801012055	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
502801012056	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
502801012057	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
502801012058	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
502801012059	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
502801012060	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
502801012061	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
502801012062	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
502801012063	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
502801012064	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
502801012065	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
502801012066	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
502801012067	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
502801012068	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
502801012069	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
502801012070	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
502801012071	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
502801012072	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
502801012073	putative antibiotic transporter; Provisional; Region: PRK10739
502801012074	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
502801012075	AAA domain; Region: AAA_33; pfam13671
502801012076	ATP-binding site [chemical binding]; other site
502801012077	Gluconate-6-phosphate binding site [chemical binding]; other site
502801012078	high-affinity gluconate transporter; Provisional; Region: PRK14984
502801012079	gluconate transporter; Region: gntP; TIGR00791
502801012080	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
502801012081	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
502801012082	DNA binding site [nucleotide binding]
502801012083	domain linker motif; other site
502801012084	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
502801012085	putative ligand binding site [chemical binding]; other site
502801012086	putative dimerization interface [polypeptide binding]; other site
502801012087	Pirin-related protein [General function prediction only]; Region: COG1741
502801012088	Pirin; Region: Pirin; pfam02678
502801012089	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
502801012090	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801012091	active site
502801012092	phosphorylation site [posttranslational modification]
502801012093	intermolecular recognition site; other site
502801012094	dimerization interface [polypeptide binding]; other site
502801012095	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
502801012096	DNA binding site [nucleotide binding]
502801012097	Adenosine kinase (AK) catalyzes the phosphorylation of ribofuranosyl-containing nucleoside analogues at the 5'-hydroxyl using ATP or GTP as the phosphate donor.The physiological function of AK is associated with the regulation of extracellular...; Region: adenosine_kinase; cd01168
502801012098	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
502801012099	substrate binding site [chemical binding]; other site
502801012100	ATP binding site [chemical binding]; other site
502801012101	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
502801012102	intersubunit interface [polypeptide binding]; other site
502801012103	active site
502801012104	zinc binding site [ion binding]; other site
502801012105	Na+ binding site [ion binding]; other site
502801012106	ABC-type sugar transport system, auxiliary component [General function prediction only]; Region: COG3822
502801012107	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
502801012108	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321
502801012109	putative ligand binding site [chemical binding]; other site
502801012110	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801012111	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801012112	TM-ABC transporter signature motif; other site
502801012113	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
502801012114	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801012115	Walker A/P-loop; other site
502801012116	ATP binding site [chemical binding]; other site
502801012117	Q-loop/lid; other site
502801012118	ABC transporter signature motif; other site
502801012119	Walker B; other site
502801012120	D-loop; other site
502801012121	H-loop/switch region; other site
502801012122	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801012123	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
502801012124	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801012125	dimerization interface [polypeptide binding]; other site
502801012126	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
502801012127	dimer interface [polypeptide binding]; other site
502801012128	phosphorylation site [posttranslational modification]
502801012129	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801012130	ATP binding site [chemical binding]; other site
502801012131	Mg2+ binding site [ion binding]; other site
502801012132	G-X-G motif; other site
502801012133	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
502801012134	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801012135	active site
502801012136	phosphorylation site [posttranslational modification]
502801012137	intermolecular recognition site; other site
502801012138	dimerization interface [polypeptide binding]; other site
502801012139	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
502801012140	AAA domain; Region: AAA_13; pfam13166
502801012141	Walker A/P-loop; other site
502801012142	ATP binding site [chemical binding]; other site
502801012143	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
502801012144	active site
502801012145	NTP binding site [chemical binding]; other site
502801012146	metal binding triad [ion binding]; metal-binding site
502801012147	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cd01483
502801012148	ATP binding site [chemical binding]; other site
502801012149	Mpr1p, Pad1p N-terminal (MPN) domains; Region: MPN; cl13996
502801012150	AAA domain; Region: AAA_22; pfam13401
502801012151	AAA ATPase domain; Region: AAA_16; pfam13191
502801012152	Integrase core domain; Region: rve; pfam00665
502801012153	TnsA endonuclease N terminal; Region: Tn7_Tnp_TnsA_N; pfam08722
502801012154	TnsA endonuclease C terminal; Region: Tn7_Tnp_TnsA_C; pfam08721
502801012155	Predicted flavoproteins [General function prediction only]; Region: COG2081
502801012156	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
502801012157	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
502801012158	universal stress protein UspB; Provisional; Region: PRK04960
502801012159	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
502801012160	Ligand Binding Site [chemical binding]; other site
502801012161	glutamate dehydrogenase; Provisional; Region: PRK09414
502801012162	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
502801012163	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
502801012164	NAD(P) binding site [chemical binding]; other site
502801012165	Zinc-dependent metalloprotease, serralysin_like subfamily. Serralysins and related proteases are important virulence factors in pathogenic bacteria. They may be secreted into the medium via a mechanism found in gram-negative bacteria, that does not...; Region: ZnMc_serralysin_like; cd04277
502801012166	active site
502801012167	Peptidase M10 serralysin C terminal; Region: Peptidase_M10_C; pfam08548
502801012168	putative methyltransferase; Provisional; Region: PRK10742
502801012169	oligopeptidase A; Provisional; Region: PRK10911
502801012170	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
502801012171	active site
502801012172	Zn binding site [ion binding]; other site
502801012173	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
502801012174	glutathione reductase; Validated; Region: PRK06116
502801012175	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
502801012176	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
502801012177	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
502801012178	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
502801012179	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
502801012180	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
502801012181	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
502801012182	fructuronate transporter; Provisional; Region: PRK10034; cl15264
502801012183	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
502801012184	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
502801012185	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
502801012186	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
502801012187	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
502801012188	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
502801012189	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
502801012190	Autotransporter beta-domain; Region: Autotransporter; smart00869
502801012191	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
502801012192	CDP-diacylglycerol pyrophosphatase [Lipid metabolism]; Region: Cdh; COG2134
502801012193	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
502801012194	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
502801012195	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
502801012196	Uncharacterized protein, 4-oxalocrotonate tautomerase homolog [General function prediction only]; Region: COG1942
502801012197	active site 1 [active]
502801012198	dimer interface [polypeptide binding]; other site
502801012199	hexamer interface [polypeptide binding]; other site
502801012200	active site 2 [active]
502801012201	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
502801012202	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
502801012203	substrate binding site [chemical binding]; other site
502801012204	ATP binding site [chemical binding]; other site
502801012205	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
502801012206	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
502801012207	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
502801012208	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
502801012209	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
502801012210	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
502801012211	sugar binding site [chemical binding]; other site
502801012212	Periplasmic pectate lyase; Region: Pectate_lyase_2; pfam06917
502801012213	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
502801012214	biofilm formation regulator HmsP; Provisional; Region: PRK11829
502801012215	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
502801012216	metal binding site [ion binding]; metal-binding site
502801012217	active site
502801012218	I-site; other site
502801012219	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
502801012220	endo-1,4-D-glucanase; Provisional; Region: PRK11097
502801012221	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
502801012222	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801012223	Walker A/P-loop; other site
502801012224	ATP binding site [chemical binding]; other site
502801012225	Q-loop/lid; other site
502801012226	ABC transporter signature motif; other site
502801012227	Walker B; other site
502801012228	D-loop; other site
502801012229	H-loop/switch region; other site
502801012230	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
502801012231	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
502801012232	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
502801012233	Walker A/P-loop; other site
502801012234	ATP binding site [chemical binding]; other site
502801012235	Q-loop/lid; other site
502801012236	ABC transporter signature motif; other site
502801012237	Walker B; other site
502801012238	D-loop; other site
502801012239	H-loop/switch region; other site
502801012240	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
502801012241	dipeptide transporter; Provisional; Region: PRK10913
502801012242	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
502801012243	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801012244	dimer interface [polypeptide binding]; other site
502801012245	conserved gate region; other site
502801012246	putative PBP binding loops; other site
502801012247	ABC-ATPase subunit interface; other site
502801012248	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
502801012249	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801012250	dimer interface [polypeptide binding]; other site
502801012251	conserved gate region; other site
502801012252	putative PBP binding loops; other site
502801012253	ABC-ATPase subunit interface; other site
502801012254	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
502801012255	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
502801012256	peptide binding site [polypeptide binding]; other site
502801012257	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
502801012258	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
502801012259	Haemolysin secretion/activation protein ShlB/FhaC/HecB; Region: ShlB; pfam03865
502801012260	haemagglutination activity domain; Region: Haemagg_act; pfam05860
502801012261	regulatory protein UhpC; Provisional; Region: PRK11663
502801012262	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801012263	putative substrate translocation pore; other site
502801012264	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801012265	sensory histidine kinase UhpB; Provisional; Region: PRK11644
502801012266	MASE1; Region: MASE1; pfam05231
502801012267	Histidine kinase; Region: HisKA_3; pfam07730
502801012268	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
502801012269	ATP binding site [chemical binding]; other site
502801012270	Mg2+ binding site [ion binding]; other site
502801012271	G-X-G motif; other site
502801012272	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
502801012273	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
502801012274	active site
502801012275	phosphorylation site [posttranslational modification]
502801012276	intermolecular recognition site; other site
502801012277	dimerization interface [polypeptide binding]; other site
502801012278	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
502801012279	DNA binding residues [nucleotide binding]
502801012280	dimerization interface [polypeptide binding]; other site
502801012281	phosphoethanolamine transferase; Provisional; Region: PRK11560
502801012282	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
502801012283	Sulfatase; Region: Sulfatase; pfam00884
502801012284	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
502801012285	putative proline-specific permease; Provisional; Region: proY; PRK10580
502801012286	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
502801012287	active sites [active]
502801012288	tetramer interface [polypeptide binding]; other site
502801012289	urocanate hydratase; Provisional; Region: PRK05414
502801012290	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
502801012291	catalytic residue [active]
502801012292	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
502801012293	active site
502801012294	hypothetical protein; Provisional; Region: PRK07206
502801012295	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
502801012296	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
502801012297	Siderophore binding protein FatB.  These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140
502801012298	putative ligand binding residues [chemical binding]; other site
502801012299	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
502801012300	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801012301	ABC-ATPase subunit  interface; other site
502801012302	dimer interface [polypeptide binding]; other site
502801012303	putative PBP binding regions; other site
502801012304	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
502801012305	ABC-ATPase subunit  interface; other site
502801012306	dimer interface [polypeptide binding]; other site
502801012307	putative PBP binding regions; other site
502801012308	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
502801012309	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
502801012310	Walker A/P-loop; other site
502801012311	ATP binding site [chemical binding]; other site
502801012312	Q-loop/lid; other site
502801012313	ABC transporter signature motif; other site
502801012314	Walker B; other site
502801012315	D-loop; other site
502801012316	H-loop/switch region; other site
502801012317	Virulence protein [General function prediction only]; Region: COG3943
502801012318	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
502801012319	Predicted transcriptional regulator [Transcription]; Region: COG3888
502801012320	Methyltransferase domain; Region: Methyltransf_27; pfam13708
502801012321	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
502801012322	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
502801012323	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
502801012324	MPN+ (JAMM) motif; other site
502801012325	Zinc-binding site [ion binding]; other site
502801012326	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
502801012327	Switch II region; other site
502801012328	Predicted GTPase [General function prediction only]; Region: COG3596
502801012329	G4 box; other site
502801012330	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
502801012331	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
502801012332	transposase/IS protein; Provisional; Region: PRK09183
502801012333	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801012334	Walker A motif; other site
502801012335	ATP binding site [chemical binding]; other site
502801012336	Walker B motif; other site
502801012337	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
502801012338	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
502801012339	DNA-binding interface [nucleotide binding]; DNA binding site
502801012340	Integrase core domain; Region: rve; pfam00665
502801012341	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
502801012342	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
502801012343	Mrr N-terminal domain; Region: Mrr_N; pfam14338
502801012344	Restriction endonuclease; Region: Mrr_cat; pfam04471
502801012345	Protein of unknown function DUF45; Region: DUF45; pfam01863
502801012346	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
502801012347	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
502801012348	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
502801012349	ATP binding site [chemical binding]; other site
502801012350	putative Mg++ binding site [ion binding]; other site
502801012351	Virulence protein [General function prediction only]; Region: COG3943
502801012352	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
502801012353	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
502801012354	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
502801012355	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
502801012356	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
502801012357	HsdM N-terminal domain; Region: HsdM_N; pfam12161
502801012358	Methyltransferase domain; Region: Methyltransf_26; pfam13659
502801012359	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
502801012360	integrase; Provisional; Region: PRK09692
502801012361	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
502801012362	active site
502801012363	Int/Topo IB signature motif; other site
502801012364	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
502801012365	putative dimerization interface [polypeptide binding]; other site
502801012366	Transcriptional regulators [Transcription]; Region: PurR; COG1609
502801012367	putative ligand binding site [chemical binding]; other site
502801012368	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801012369	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
502801012370	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
502801012371	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
502801012372	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
502801012373	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
502801012374	TM-ABC transporter signature motif; other site
502801012375	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
502801012376	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
502801012377	Walker A/P-loop; other site
502801012378	ATP binding site [chemical binding]; other site
502801012379	Q-loop/lid; other site
502801012380	ABC transporter signature motif; other site
502801012381	Walker B; other site
502801012382	D-loop; other site
502801012383	H-loop/switch region; other site
502801012384	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
502801012385	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
502801012386	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
502801012387	putative ligand binding site [chemical binding]; other site
502801012388	xylose isomerase; Provisional; Region: PRK05474
502801012389	xylose isomerase; Region: xylose_isom_A; TIGR02630
502801012390	xylulokinase; Provisional; Region: PRK15027
502801012391	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
502801012392	N- and C-terminal domain interface [polypeptide binding]; other site
502801012393	active site
502801012394	MgATP binding site [chemical binding]; other site
502801012395	catalytic site [active]
502801012396	metal binding site [ion binding]; metal-binding site
502801012397	xylulose binding site [chemical binding]; other site
502801012398	homodimer interface [polypeptide binding]; other site
502801012399	Fimbrial protein; Region: Fimbrial; pfam00419
502801012400	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
502801012401	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
502801012402	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
502801012403	fimbrial outer membrane usher protein StdB; Provisional; Region: PRK15255
502801012404	PapC N-terminal domain; Region: PapC_N; pfam13954
502801012405	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
502801012406	PapC C-terminal domain; Region: PapC_C; pfam13953
502801012407	Fimbrial protein; Region: Fimbrial; cl01416
502801012408	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
502801012409	Acyltransferase family; Region: Acyl_transf_3; pfam01757
502801012410	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
502801012411	Helix-turn-helix domain; Region: HTH_28; pfam13518
502801012412	Helix-turn-helix domain; Region: HTH_28; pfam13518
502801012413	putative transposase OrfB; Reviewed; Region: PHA02517
502801012414	HTH-like domain; Region: HTH_21; pfam13276
502801012415	Integrase core domain; Region: rve; pfam00665
502801012416	Integrase core domain; Region: rve_2; pfam13333
502801012417	Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; Region: COG2423
502801012418	ornithine cyclodeaminase; Validated; Region: PRK06823
502801012419	hypothetical protein; Provisional; Region: PRK06815
502801012420	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
502801012421	tetramer interface [polypeptide binding]; other site
502801012422	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801012423	catalytic residue [active]
502801012424	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
502801012425	hypothetical protein; Provisional; Region: PRK11616
502801012426	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
502801012427	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
502801012428	putative dimer interface [polypeptide binding]; other site
502801012429	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
502801012430	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
502801012431	putative dimer interface [polypeptide binding]; other site
502801012432	putative transporter; Validated; Region: PRK03818
502801012433	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
502801012434	TrkA-C domain; Region: TrkA_C; pfam02080
502801012435	TrkA-C domain; Region: TrkA_C; pfam02080
502801012436	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
502801012437	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
502801012438	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
502801012439	pyridoxal 5'-phosphate binding site [chemical binding]; other site
502801012440	homodimer interface [polypeptide binding]; other site
502801012441	catalytic residue [active]
502801012442	alpha-amylase; Reviewed; Region: malS; PRK09505
502801012443	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
502801012444	active site
502801012445	catalytic site [active]
502801012446	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
502801012447	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
502801012448	dimerization interface [polypeptide binding]; other site
502801012449	ligand binding site [chemical binding]; other site
502801012450	NADP binding site [chemical binding]; other site
502801012451	catalytic site [active]
502801012452	Predicted transcriptional regulator [Transcription]; Region: COG2345
502801012453	putative outer membrane lipoprotein; Provisional; Region: PRK10510
502801012454	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
502801012455	ligand binding site [chemical binding]; other site
502801012456	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
502801012457	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
502801012458	Coenzyme A binding pocket [chemical binding]; other site
502801012459	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
502801012460	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
502801012461	dimer interface [polypeptide binding]; other site
502801012462	motif 1; other site
502801012463	active site
502801012464	motif 2; other site
502801012465	motif 3; other site
502801012466	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
502801012467	DALR anticodon binding domain; Region: DALR_1; pfam05746
502801012468	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
502801012469	Yersinia protein of unknown function (DUF3831); Region: DUF3831; pfam12908
502801012470	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
502801012471	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
502801012472	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
502801012473	active site
502801012474	P-loop; other site
502801012475	phosphorylation site [posttranslational modification]
502801012476	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
502801012477	active site
502801012478	phosphorylation site [posttranslational modification]
502801012479	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
502801012480	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
502801012481	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
502801012482	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
502801012483	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
502801012484	hypothetical protein; Provisional; Region: PRK11020
502801012485	Electron transfer DM13; Region: DM13; pfam10517
502801012486	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
502801012487	dimerization interface [polypeptide binding]; other site
502801012488	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
502801012489	dimer interface [polypeptide binding]; other site
502801012490	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
502801012491	putative CheW interface [polypeptide binding]; other site
502801012492	superoxide dismutase; Provisional; Region: PRK10925
502801012493	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
502801012494	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
502801012495	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
502801012496	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
502801012497	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
502801012498	molybdopterin cofactor binding site; other site
502801012499	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
502801012500	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
502801012501	molybdopterin cofactor binding site; other site
502801012502	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
502801012503	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
502801012504	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
502801012505	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
502801012506	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
502801012507	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
502801012508	selenocysteine synthase; Provisional; Region: PRK04311
502801012509	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
502801012510	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
502801012511	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
502801012512	catalytic residue [active]
502801012513	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
502801012514	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
502801012515	G1 box; other site
502801012516	putative GEF interaction site [polypeptide binding]; other site
502801012517	GTP/Mg2+ binding site [chemical binding]; other site
502801012518	Switch I region; other site
502801012519	G2 box; other site
502801012520	G3 box; other site
502801012521	Switch II region; other site
502801012522	G4 box; other site
502801012523	G5 box; other site
502801012524	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
502801012525	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
502801012526	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
502801012527	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
502801012528	Transcriptional regulators [Transcription]; Region: FadR; COG2186
502801012529	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
502801012530	DNA-binding site [nucleotide binding]; DNA binding site
502801012531	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
502801012532	putative transporter; Provisional; Region: PRK10504
502801012533	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
502801012534	putative substrate translocation pore; other site
502801012535	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
502801012536	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
502801012537	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
502801012538	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
502801012539	substrate binding site [chemical binding]; other site
502801012540	dimer interface [polypeptide binding]; other site
502801012541	ATP binding site [chemical binding]; other site
502801012542	D-ribose pyranase; Provisional; Region: PRK11797
502801012543	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
502801012544	potassium uptake protein; Region: kup; TIGR00794
502801012545	regulatory ATPase RavA; Provisional; Region: PRK13531
502801012546	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801012547	Walker A motif; other site
502801012548	ATP binding site [chemical binding]; other site
502801012549	Walker B motif; other site
502801012550	arginine finger; other site
502801012551	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
502801012552	hypothetical protein; Provisional; Region: yieM; PRK10997
502801012553	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
502801012554	metal ion-dependent adhesion site (MIDAS); other site
502801012555	Asparagine synthetase A [Amino acid transport and metabolism]; Region: AsnA; COG2502
502801012556	motif 1; other site
502801012557	dimer interface [polypeptide binding]; other site
502801012558	active site
502801012559	motif 2; other site
502801012560	motif 3; other site
502801012561	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
502801012562	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
502801012563	putative DNA binding site [nucleotide binding]; other site
502801012564	putative Zn2+ binding site [ion binding]; other site
502801012565	AsnC family; Region: AsnC_trans_reg; pfam01037
502801012566	FMN-binding protein MioC; Provisional; Region: PRK09004
502801012567	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
502801012568	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
502801012569	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
502801012570	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
502801012571	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
502801012572	S-adenosylmethionine binding site [chemical binding]; other site
502801012573	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
502801012574	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
502801012575	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
502801012576	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
502801012577	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
502801012578	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
502801012579	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
502801012580	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
502801012581	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
502801012582	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
502801012583	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
502801012584	beta subunit interaction interface [polypeptide binding]; other site
502801012585	Walker A motif; other site
502801012586	ATP binding site [chemical binding]; other site
502801012587	Walker B motif; other site
502801012588	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
502801012589	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
502801012590	core domain interface [polypeptide binding]; other site
502801012591	delta subunit interface [polypeptide binding]; other site
502801012592	epsilon subunit interface [polypeptide binding]; other site
502801012593	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
502801012594	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
502801012595	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
502801012596	alpha subunit interaction interface [polypeptide binding]; other site
502801012597	Walker A motif; other site
502801012598	ATP binding site [chemical binding]; other site
502801012599	Walker B motif; other site
502801012600	inhibitor binding site; inhibition site
502801012601	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
502801012602	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
502801012603	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
502801012604	gamma subunit interface [polypeptide binding]; other site
502801012605	epsilon subunit interface [polypeptide binding]; other site
502801012606	LBP interface [polypeptide binding]; other site
502801012607	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
502801012608	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
502801012609	Substrate binding site; other site
502801012610	Mg++ binding site; other site
502801012611	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
502801012612	active site
502801012613	substrate binding site [chemical binding]; other site
502801012614	CoA binding site [chemical binding]; other site
502801012615	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
502801012616	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
502801012617	glutaminase active site [active]
502801012618	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
502801012619	dimer interface [polypeptide binding]; other site
502801012620	active site
502801012621	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
502801012622	dimer interface [polypeptide binding]; other site
502801012623	active site
502801012624	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801012625	substrate binding pocket [chemical binding]; other site
502801012626	membrane-bound complex binding site; other site
502801012627	hinge residues; other site
502801012628	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
502801012629	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801012630	dimer interface [polypeptide binding]; other site
502801012631	conserved gate region; other site
502801012632	putative PBP binding loops; other site
502801012633	ABC-ATPase subunit interface; other site
502801012634	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
502801012635	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801012636	dimer interface [polypeptide binding]; other site
502801012637	conserved gate region; other site
502801012638	putative PBP binding loops; other site
502801012639	ABC-ATPase subunit interface; other site
502801012640	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
502801012641	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
502801012642	Walker A/P-loop; other site
502801012643	ATP binding site [chemical binding]; other site
502801012644	Q-loop/lid; other site
502801012645	ABC transporter signature motif; other site
502801012646	Walker B; other site
502801012647	D-loop; other site
502801012648	H-loop/switch region; other site
502801012649	transcriptional regulator PhoU; Provisional; Region: PRK11115
502801012650	PhoU domain; Region: PhoU; pfam01895
502801012651	PhoU domain; Region: PhoU; pfam01895
502801012652	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
502801012653	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
502801012654	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
502801012655	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
502801012656	substrate binding pocket [chemical binding]; other site
502801012657	membrane-bound complex binding site; other site
502801012658	hinge residues; other site
502801012659	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
502801012660	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801012661	dimer interface [polypeptide binding]; other site
502801012662	conserved gate region; other site
502801012663	putative PBP binding loops; other site
502801012664	ABC-ATPase subunit interface; other site
502801012665	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
502801012666	dimer interface [polypeptide binding]; other site
502801012667	conserved gate region; other site
502801012668	putative PBP binding loops; other site
502801012669	ABC-ATPase subunit interface; other site
502801012670	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
502801012671	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
502801012672	motif II; other site
502801012673	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
502801012674	Protein of unknown function (DUF1240); Region: DUF1240; pfam06836
502801012675	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
502801012676	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
502801012677	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
502801012678	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
502801012679	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
502801012680	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
502801012681	trmE is a tRNA modification GTPase; Region: trmE; cd04164
502801012682	G1 box; other site
502801012683	GTP/Mg2+ binding site [chemical binding]; other site
502801012684	Switch I region; other site
502801012685	G2 box; other site
502801012686	Switch II region; other site
502801012687	G3 box; other site
502801012688	G4 box; other site
502801012689	G5 box; other site
502801012690	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
502801012691	membrane protein insertase; Provisional; Region: PRK01318
502801012692	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
502801012693	hypothetical protein; Validated; Region: PRK00041
502801012694	ribonuclease P; Reviewed; Region: rnpA; PRK01732
502801012695	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
502801012696	type III secretion system chaperone, YscB family; Region: type_III_yscB; TIGR02513
502801012697	type III secretion outer membrane pore, YscC/HrcC family; Region: type_III_yscC; TIGR02516
502801012698	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
502801012699	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
502801012700	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
502801012701	type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500
502801012702	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cl00062
502801012703	phosphopeptide binding site; other site
502801012704	type III secretion system protein SsaD; Provisional; Region: PRK15367
502801012705	Protein of unknown function (DUF1895); Region: DUF1895; pfam08988
502801012706	type III secretion apparatus needle protein; Region: III_needle; TIGR02105
502801012707	type III secretion protein, YscG family; Region: type_III_yscG; TIGR02508
502801012708	type III secretion effector, YopR family; Region: type_III_yopR; TIGR02509
502801012709	type III secretion apparatus protein, YscI/HrpB, C-terminal domain; Region: yscI_hrpB_dom; TIGR02497
502801012710	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
502801012711	YOP proteins translocation protein K (YscK); Region: YscK; pfam06578
502801012712	type III secretion system protein; Reviewed; Region: PRK06937
502801012713	Flagellar assembly protein FliH; Region: FliH; pfam02108
502801012714	YopH, N-terminal; Region: YopH_N; pfam09013
502801012715	Transposase; Region: HTH_Tnp_1; pfam01527
502801012716	YopH, N-terminal; Region: YopH_N; pfam09013
502801012717	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cd00047
502801012718	Protein-tyrosine phosphatase; Region: Y_phosphatase; pfam00102
502801012719	active site
502801012720	Integrase core domain; Region: rve; pfam00665
502801012721	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
502801012722	Integrase core domain; Region: rve_3; pfam13683
502801012723	effector protein YopJ; Provisional; Region: PRK15371
502801012724	Protein kinase domain; Region: Pkinase; pfam00069
502801012725	Catalytic domain of Protein Kinases; Region: PKc; cd00180
502801012726	active site
502801012727	ATP binding site [chemical binding]; other site
502801012728	substrate binding site [chemical binding]; other site
502801012729	activation loop (A-loop); other site
502801012730	Rac1-binding domain; Region: Rac1; pfam09632
502801012731	Tir chaperone protein (CesT); Region: CesT; cl08444
502801012732	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
502801012733	Integrase core domain; Region: rve_3; cl15866
502801012734	replication protein; Provisional; Region: PRK13750
502801012735	replication protein; Provisional; Region: PRK13702
502801012736	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
502801012737	PLD-like domain; Region: PLDc_2; pfam13091
502801012738	putative active site [active]
502801012739	catalytic site [active]
502801012740	HTH-like domain; Region: HTH_21; pfam13276
502801012741	Integrase core domain; Region: rve; pfam00665
502801012742	Transposase; Region: HTH_Tnp_1; pfam01527
502801012743	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
502801012744	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK13709
502801012745	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl01116
502801012746	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
502801012747	trimer interface [polypeptide binding]; other site
502801012748	YadA-like C-terminal region; Region: YadA; pfam03895
502801012749	HTH-like domain; Region: HTH_21; pfam13276
502801012750	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
502801012751	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
502801012752	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
502801012753	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
502801012754	catalytic residues [active]
502801012755	catalytic nucleophile [active]
502801012756	Presynaptic Site I dimer interface [polypeptide binding]; other site
502801012757	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
502801012758	Synaptic Flat tetramer interface [polypeptide binding]; other site
502801012759	Synaptic Site I dimer interface [polypeptide binding]; other site
502801012760	DNA binding site [nucleotide binding]
502801012761	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
502801012762	DNA-binding interface [nucleotide binding]; DNA binding site
502801012763	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
502801012764	DNA-binding interface [nucleotide binding]; DNA binding site
502801012765	insertion element IS2 transposase InsD; Provisional; Region: PRK14702
502801012766	HTH-like domain; Region: HTH_21; pfam13276
502801012767	Integrase core domain; Region: rve; pfam00665
502801012768	Integrase core domain; Region: rve_3; pfam13683
502801012769	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
502801012770	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
502801012771	Walker A motif; other site
502801012772	ATP binding site [chemical binding]; other site
502801012773	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
502801012774	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
502801012775	Integrase core domain; Region: rve; pfam00665
502801012776	Integrase core domain; Region: rve_3; cl15866
502801012777	Integrase core domain; Region: rve; pfam00665
502801012778	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
502801012779	YopE, N terminal; Region: YopE_N; pfam09020
502801012780	GTPase-activating protein (GAP) domain found in bacterial cytotoxins, ExoS, SptP, and YopE. Part of protein secretion system; stimulates Rac1- dependent cytoskeletal changes that promote bacterial internalization; Region: ToxGAP; cd00219
502801012781	switch II binding region; other site
502801012782	Rac1 P-loop interaction site [polypeptide binding]; other site
502801012783	GTP binding residues [chemical binding]; other site
502801012784	switch I binding region; other site
502801012785	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
502801012786	putative addiction module antidote protein, CC2985 family; Region: antidote_CC2985; TIGR02606
502801012787	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
502801012788	plasmid-partitioning protein; Provisional; Region: PRK13698
502801012789	ParB-like nuclease domain; Region: ParB; smart00470
502801012790	plasmid-partitioning protein SopA; Provisional; Region: PRK13705
502801012791	MerR family regulatory protein; Region: MerR; pfam00376
502801012792	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
502801012793	P-loop; other site
502801012794	Magnesium ion binding site [ion binding]; other site
502801012795	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
502801012796	Magnesium ion binding site [ion binding]; other site
502801012797	Integrase core domain; Region: rve_3; cl15866
502801012798	HTH-like domain; Region: HTH_21; pfam13276
502801012799	Integrase core domain; Region: rve; pfam00665
502801012800	Transposase; Region: HTH_Tnp_1; pfam01527
502801012801	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
502801012802	Enterobacterial TraT complement resistance protein; Region: TraT; pfam05818
502801012803	Yersinia/Haemophilus virulence surface antigen; Region: Peptidase_C58; pfam03543
502801012804	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
502801012805	hypothetical protein; Provisional; Region: PRK11622
502801012806	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
502801012807	Type III secretion system leucine rich repeat protein; Region: TTSSLRR; pfam12468
502801012808	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cl15309
502801012809	Leucine-rich repeats; other site
502801012810	Substrate binding site [chemical binding]; other site
502801012811	Leucine Rich repeats (2 copies); Region: LRR_4; pfam12799
502801012812	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
502801012813	MULE transposase domain; Region: MULE; pfam10551
502801012814	YopD protein; Region: YopD; pfam05844
502801012815	Uncharacterized conserved protein [Function unknown]; Region: COG5613
502801012816	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
502801012817	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
502801012818	binding surface
502801012819	TPR motif; other site
502801012820	V antigen (LcrV) protein; Region: LcrV; pfam04792
502801012821	type III secretion protein LcrG; Region: LcrG_PcrG; TIGR02573
502801012822	Type III secretion system regulator (LcrR); Region: LcrR; cl09838
502801012823	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
502801012824	FHIPEP family; Region: FHIPEP; pfam00771
502801012825	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
502801012826	type III secretion protein, YscX family; Region: type_III_YscX; TIGR02502
502801012827	type III secretion chaperone SycN; Region: type_III_SycN; TIGR02503
502801012828	TyeA; Region: TyeA; pfam09059
502801012829	HrpJ-like domain; Region: HrpJ; cl15454
502801012830	type III secretion system ATPase; Provisional; Region: PRK06936
502801012831	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
502801012832	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
502801012833	Walker A motif/ATP binding site; other site
502801012834	Walker B motif; other site
502801012835	Type III secretion protein YscO; Region: YscO; pfam07321
502801012836	type III secretion system needle length determinant; Region: type_III_yscP; TIGR02514
502801012837	type III secretion system protein; Validated; Region: PRK06933
502801012838	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
502801012839	Type III secretory pathway, component EscR [Intracellular trafficking and secretion]; Region: EscR; COG4790
502801012840	Type III secretory pathway, component EscS [Intracellular trafficking and secretion]; Region: EscS; COG4794
502801012841	Type III secretory pathway, component EscT [Intracellular trafficking and secretion]; Region: EscT; COG4791
502801012842	Type III secretory pathway, component EscU [Intracellular trafficking and secretion]; Region: EscU; COG4792
502801012843	type III secretion system chaperone YscW; Region: YscW; TIGR02567