-- dump date 20111121_015802 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_004734465.1 340616012 10974013 139..1563 1 NC_015844.1 DnaA is a replication initiation factor that plays an important role in the initiation and regulation of chromosomal replication. DnaA promotes the unwinding of DNA at the chromosome origin of replication (oriC), during DNA replication. The formation of the oriC/DnaA complex and DNA unwinding requires ATP hydrolysis. Some 20 DnaA protein molecules bind specifically to double-stranded DNA at a 9 bp consensus (dnaA box) found in the oriC. DnaA is an ATP-and DNA-binding protein. Its N-terminal half binds to the ATP and its C-terminal half could be involved in DNA-binding via an helix-turn-helix domain; Localized in the cytoplasm; High confidence in function and specificity; chromosomal replication initiator protein DnaA 1563 dnaA 10974013 dnaA Zobellia galactanivorans chromosomal replication initiator protein DnaA YP_004734465.1 139 D 63186 CDS YP_004734466.1 340616013 10977748 1570..2016 1 NC_015844.1 The low molecular weight (LMW) protein-tyrosine phosphatases (or acid phosphatases) catalyse the removal of a phosphate group attached to a tyrosine residue, using a cysteinyl-phosphate enzyme intermediate; Belongs to the Tyrosine-specific protein phosphatases family; Localized in the cytoplasm; High confidence in function and specificity; low molecular weight protein-tyrosine-phosphatase 2016 ptpA 10977748 ptpA Zobellia galactanivorans low molecular weight protein-tyrosine-phosphatase YP_004734466.1 1570 D 63186 CDS YP_004734467.1 340616014 10978397 2030..2755 1 NC_015844.1 Enzyme that uses S-AdoMet in the methylation of diverse substrates; Belongs to the UPF0011 family; Localized in the cytoplasm; Specificity unclear; methyltransferase 2755 10978397 zobellia_2 Zobellia galactanivorans methyltransferase YP_004734467.1 2030 D 63186 CDS YP_004734468.1 340616015 10974842 2917..3462 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3462 10974842 zobellia_3 Zobellia galactanivorans hypothetical protein YP_004734468.1 2917 D 63186 CDS YP_004734469.1 340616016 10975620 complement(3642..4271) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplamic space; Conserved hypothetical protein; periplasmic protein 4271 10975620 zobellia_4 Zobellia galactanivorans periplasmic protein YP_004734469.1 3642 R 63186 CDS YP_004734470.1 340616017 10976483 complement(4418..5461) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Belongs to the aminodeoxychorismate lyase family; Localized in the periplasmic space; Family membership; periplasmic protein 5461 10976483 zobellia_5 Zobellia galactanivorans periplasmic protein YP_004734470.1 4418 R 63186 CDS YP_004734471.1 340616018 10977130 complement(5461..5985) 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 5985 10977130 zobellia_6 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004734471.1 5461 R 63186 CDS YP_004734472.1 340616019 10977205 complement(5979..6707) 1 NC_015844.1 The diaminopimelate epimerase catalyses the isomerisation of L,L-dimaminopimelate to meso-DAP in the biosynthetic pathway leading from aspartate to lysine; The meso-DAP is subsequently converted to lysine by a decarboxylase, or, in Gram-negative bacteria, assimilated into the cell wall; Enzyme consists of two domains of the same alpha/beta fold; Localized in the cytoplasm; High confidence in function and specificity; diaminopimelate epimerase 6707 dapF 10977205 dapF Zobellia galactanivorans diaminopimelate epimerase YP_004734472.1 5979 R 63186 CDS YP_004734473.1 340616020 10977718 6941..8332 1 NC_015844.1 Peptidase Do is a heat shock protein which is required for bacterial growth at elevated temperatures. It is involved in the degradation of damaged proteins. Belongs to the family 1 of the serine peptidase. Displays a catalytic triad His, Asp and Ser. Contains a C-terminal PDZ domain. Features an uncleaved signal peptide. Localized in the cytoplasmic membrane.; High confidence in function and specificity; peptidase Do, family S1 8332 degP 10977718 degP Zobellia galactanivorans peptidase Do, family S1 YP_004734473.1 6941 D 63186 CDS YP_004734474.1 340616021 10977730 8449..9897 1 NC_015844.1 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity; glyceraldehyde 3-phosphate dehydrogenase 9897 gapD 10977730 gapD Zobellia galactanivorans glyceraldehyde 3-phosphate dehydrogenase YP_004734474.1 8449 D 63186 CDS YP_004734475.1 340616022 10977880 9894..9986 1 NC_015844.1 Hypothetical protein; hypothetical protein 9986 10977880 zobellia_10 Zobellia galactanivorans hypothetical protein YP_004734475.1 9894 D 63186 CDS YP_004734476.1 340616023 10974060 10047..10673 1 NC_015844.1 Contains one C-terminal transmembrane segment; Signal peptide cleaved between the residues 21 and 22; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 10673 10974060 zobellia_11 Zobellia galactanivorans membrane protein YP_004734476.1 10047 D 63186 CDS YP_004734477.1 340616024 10974150 10941..11615 1 NC_015844.1 The tRNA (guanine-N1-)-methyltransferase catalyses the methylation of guanoside (G) to N1-methylguanosine (m1G) at position 37, next to the anticodon, of tRNAs that read CUN (leucine), CCN(proline), and CGG (arginine) codons; Belongs to the tRNA methyltransferase family; Localized in the cytoplasm; High confidence in function and specificity; tRNA (guanine-N1-)-methyltransferase 11615 trmD 10974150 trmD Zobellia galactanivorans tRNA (guanine-N1-)-methyltransferase YP_004734477.1 10941 D 63186 CDS YP_004734478.1 340616025 10978688 11755..12105 1 NC_015844.1 Ribosomal protein L19 is a part of the small (50S) ribosomal subunit. The protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; Belongs to the ribosomal protein L19p family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L19 12105 rplS 10978688 rplS Zobellia galactanivorans 50S ribosomal protein L19 YP_004734478.1 11755 D 63186 CDS YP_004734479.1 340616026 10978509 complement(12243..12467) 1 NC_015844.1 Hypothetical protein; hypothetical protein 12467 10978509 zobellia_14 Zobellia galactanivorans hypothetical protein YP_004734479.1 12243 R 63186 CDS YP_004734480.1 340616027 10974374 12820..15039 1 NC_015844.1 NADP(+)-dependent isocitrate dehydrogenase (ICD) is an important enzyme of the intermediary metabolism, as it controls the carbon flux within the citric acid cycle and supplies the cell to 2-oxoglutarate and NADPH for biosynthetic purposes; The activity of this enzyme, which is controlled by phosphorylation, helps regulate carbon flux between the Krebs cycle and the glyoxylate bypass, which is an alternate route that accumulates carbon for biosynthesis when acetate is the sole carbon source for growth; Localized in the cytoplasm; High confidence in function and specificity; isocitrate dehydrogenase NADP-dependent, monomeric type 15039 icdA 10974374 icdA Zobellia galactanivorans isocitrate dehydrogenase NADP-dependent, monomeric type YP_004734480.1 12820 D 63186 CDS YP_004734481.1 340616028 10978018 15163..17562 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (25-102) and the Plug module (119-226) acting as a channel gate; The signal peptide is cleaved between the residues 21 and 22; Family membership; TonB-dependent Receptor 17562 10978018 zobellia_16 Zobellia galactanivorans TonB-dependent Receptor YP_004734481.1 15163 D 63186 CDS YP_004734482.1 340616029 10974531 17566..18423 1 NC_015844.1 Lipoprotein signal peptide cleaved between the residues 16 and 17; Putatively localized in the outer membrane; Hypothetical protein; hypothetical protein 18423 10974531 zobellia_17 Zobellia galactanivorans hypothetical protein YP_004734482.1 17566 D 63186 CDS YP_004734483.1 340616030 10974609 18459..18701 1 NC_015844.1 Contains two transmembrane segmemnts; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 18701 10974609 zobellia_18 Zobellia galactanivorans hypothetical protein YP_004734483.1 18459 D 63186 CDS YP_004734484.1 340616031 10974683 complement(18706..19389) 1 NC_015844.1 Conserved hypothetical protein. Features a signal peptide cleaved between the residues 21 and 22. Localized in the periplasm.; hypothetical protein 19389 10974683 zobellia_19 Zobellia galactanivorans hypothetical protein YP_004734484.1 18706 R 63186 CDS YP_004734485.1 340616032 10974758 19492..20580 1 NC_015844.1 Peptidase family M42 contains metalloaminopeptidases some of which also have acylaminoacylpeptidase activity. These peptidases are co- catalytic metallopeptidases, typically binding two atoms of zinc or cobalt. Metal ligands occur in the sequence: H, D, E, D/E, H; and active site residues in the motifs HXD and EE. Localized in the cytoplasm.; Specificity unclear; metallopeptidase 20580 10974758 zobellia_20 Zobellia galactanivorans metallopeptidase YP_004734485.1 19492 D 63186 CDS YP_004734486.1 340616033 10974843 20627..21175 1 NC_015844.1 Members of the Nudix hydrolase family catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. They require Mg2+ or Mn2+, for their activity. Substrates include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & \\house- cleaning\\ enzymes; Belong to the Nudix hydrolase superfamily; Localized in the cytoplasm; Family membership; NUDIX hydrolase 21175 10974843 zobellia_21 Zobellia galactanivorans NUDIX hydrolase YP_004734486.1 20627 D 63186 CDS YP_004734487.1 340616034 10974924 complement(21170..22546) 1 NC_015844.1 Histidyl-tRNA synthetase is responsible for the attachment of histidine to the 3' OH group of ribose of its cognate transfer RNA molecule (tRNA(His)) in a highly specific two-step reaction. It is a homodimer; Belongs to the class-IIa aminoacyl-tRNA synthetase family; Localized in the cytoplasm; High confidence in function and specificity; histidyl-tRNA synthetase 22546 hisS 10974924 hisS Zobellia galactanivorans histidyl-tRNA synthetase YP_004734487.1 21170 R 63186 CDS YP_004734488.1 340616035 10977984 complement(22660..23133) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 23133 10977984 zobellia_23 Zobellia galactanivorans hypothetical protein YP_004734488.1 22660 R 63186 CDS YP_004734489.1 340616036 10975078 complement(23196..26381) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (27-112) and the Plug module (129-240) acting as a channel gate; The signal peptide is cleaved between the residues 22 and 23; Family membership; TonB-dependent Receptor 26381 10975078 zobellia_24 Zobellia galactanivorans TonB-dependent Receptor YP_004734489.1 23196 R 63186 CDS YP_004734490.1 340616037 10975143 complement(26469..26921) 1 NC_015844.1 Ribosomal protein L9 is a protein from the large ribosomal subunit (50S), known to bind directly very close to the 3' end of the 23S rRNA; Belongs to the ribosomal protein L9p family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L9 26921 rplI 10975143 rplI Zobellia galactanivorans 50S ribosomal protein L9 YP_004734490.1 26469 R 63186 CDS YP_004734491.1 340616038 10978499 complement(26934..27230) 1 NC_015844.1 The ribosomal protein S18 is a secondary rRNA binding protein of the ribosomal small subunit (30S), known to be involved in binding the aminoacyl-tRNA complex, and appears to be situated at the tRNA A-site. It binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps to stabilize the platform of the 30S subunit; Belongs to the ribosomal protein S18p family; Localized in the cytoplasm.; High confidence in function and specificity; 30S ribosomal protein S18 27230 rpsR 10978499 rpsR Zobellia galactanivorans 30S ribosomal protein S18 YP_004734491.1 26934 R 63186 CDS YP_004734492.1 340616039 10978548 complement(27237..27575) 1 NC_015844.1 The ribosomal protein S6 is a part of the ribosomal small subunit (30S). It binds as a heterodimer with protein S18 to the central domain of the 16S rRNA, where it helps to stabilize the platform of the 30S subunit; Belongs to the ribosomal protein S6p family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S6 27575 rpsF 10978548 rpsF Zobellia galactanivorans 30S ribosomal protein S6 YP_004734492.1 27237 R 63186 CDS YP_004734493.1 340616040 10978536 27805..28497 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity (here a LytTR-type HTH domain), which acts as transcriptional regulator; Localized in the cytoplasm; Family membership; two-component system-response regulator 28497 10978536 zobellia_28 Zobellia galactanivorans two-component system-response regulator YP_004734493.1 27805 D 63186 CDS YP_004734494.1 340616041 10975458 complement(28565..31018) 1 NC_015844.1 The primosomal protein N', or replication factor Y, acts as an ATP-dependant DNA helicase within the primosome; The Y factor recognizes a specific hairpin sequence on phiX ssDNA. This structure is then recognized and bound by proteins priB and priC. Formation of the primosome proceeds with the subsequent actions of dnaB, dnaC, dnaT and primase; Belongs to the superfamily II of helicases; Localized in the cytoplasm; High confidence in function and specificity; primosomal protein N' 31018 priA 10975458 priA Zobellia galactanivorans primosomal protein N' YP_004734494.1 28565 R 63186 CDS YP_004734495.1 340616042 10978381 complement(31034..31474) 1 NC_015844.1 Conserved hypothetical protein. Features a signal peptide cleaved between the residues 27 and 28. Localized in the periplasm.; hypothetical protein 31474 10978381 zobellia_30 Zobellia galactanivorans hypothetical protein YP_004734495.1 31034 R 63186 CDS YP_004734496.1 340616043 10975621 complement(31471..32439) 1 NC_015844.1 The ribonuclease BN is a 3' to 5' exoribonuclease necessary for 3' maturation of some tRNA molecules; The substrate specificity of RNase BN appears to be very narrow and its biological role is uncertain. Contains six transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity; ribonuclease BN 32439 rbnA 10975621 rbnA Zobellia galactanivorans ribonuclease BN YP_004734496.1 31471 R 63186 CDS YP_004734497.1 340616044 10978433 complement(32440..33297) 1 NC_015844.1 Quinolinic acid phosphoribosyl transferase (QPRTase or QAPRTase) or nicotinate-nucleotide pyrophosphorylase catalyses the conversion of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP), in the presence of Mg2+, to nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide. This enzyme provides the de novo source of NAMN for NAD biosynthesis; Localized in the cytoplasm; High confidence in function and specificity; quinolinate phosphoribosyl transferase 33297 nadC 10978433 nadC Zobellia galactanivorans quinolinate phosphoribosyl transferase YP_004734497.1 32440 R 63186 CDS YP_004734498.1 340616045 10978220 33427..33900 1 NC_015844.1 Conserved hypothetical protein belonging to the family DUF163. Localized in the cytoplasm.; hypothetical protein 33900 10978220 zobellia_33 Zobellia galactanivorans hypothetical protein YP_004734498.1 33427 D 63186 CDS YP_004734499.1 340616046 10975885 complement(33966..35858) 1 NC_015844.1 Bifunctional enzyme with a N-terminal phosphoserine phosphatase (SerB) and a C-terminal D-3-phosphoglycerate dehydrogenase (SerA) involved in the third and first step of the serine biosynthesis pathway respectively; SerA converts the 3-phosphonooxypyruvate to 3-phosphoglycerate. It is composed of a substrate-binding domain belonging to the D-isomer specific 2-hydroxyacid dehydrogenase family and a NAD-binding domain (Rossman fold). SerA features also a C-terminal ACT domain that adopts a ferredoxin-like fold. confering to SerA a feedback inhibition by L-serine; SerB converts the L(or D)-3-phospho-serine to L-serine. It requires magnesium as cofactor; Localized in the cytoplasm; High confidence in function and specificity; phosphoserine phosphatase / D-3-phosphoglycerate dehydrogenase 35858 serB/serA1 10975885 serB/serA1 Zobellia galactanivorans phosphoserine phosphatase / D-3-phosphoglycerate dehydrogenase YP_004734499.1 33966 R 63186 CDS YP_004734500.1 340616047 10978582 complement(36022..36822) 1 NC_015844.1 The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Signal peptide of lipoprotein cleaved between the residues 24 and 25; Possibly localized in the outer membrane; Function unclear; alpha/beta hydrolase-fold protein 36822 10978582 zobellia_35 Zobellia galactanivorans alpha/beta hydrolase-fold protein YP_004734500.1 36022 R 63186 CDS YP_004734501.1 340616048 10976074 complement(36809..37507) 1 NC_015844.1 Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 37507 10976074 zobellia_36 Zobellia galactanivorans membrane protein YP_004734501.1 36809 R 63186 CDS YP_004734502.1 340616049 10976165 complement(37508..38116) 1 NC_015844.1 Conserved hypothetical protein featuring a C-terminal helix-turn-helix DNA-binding motif. Localized in the cytoplasm.; Conserved hypothetical protein; hypothetical protein 38116 10976165 zobellia_37 Zobellia galactanivorans hypothetical protein YP_004734502.1 37508 R 63186 CDS YP_004734503.1 340616050 10976240 complement(38200..38706) 1 NC_015844.1 Could belong to the Isoprenylcysteine carboxyl methyltransferase (ICMT) family; Contains three transmembrane segments; Localized in the cytoplasmic membrane; Family membership; membrane protein 38706 10976240 zobellia_38 Zobellia galactanivorans membrane protein YP_004734503.1 38200 R 63186 CDS YP_004734504.1 340616051 10976309 38740..39309 1 NC_015844.1 Hydrolyzes, in presence of divalent cations, O6 atom-containing purine bases deoxyinosine triphosphate (dITP) and xanthosine triphosphate (XTP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) to nucleotide monophosphate and pyrophosphate. Probably excludes non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family; Localized in the cytoplasm; High confidence in function and specificity; nucleoside-triphosphate diphosphatase 39309 rdgB 10976309 rdgB Zobellia galactanivorans nucleoside-triphosphate diphosphatase YP_004734504.1 38740 D 63186 CDS YP_004734505.1 340616052 10978438 39451..41241 1 NC_015844.1 The ATP-dependent RNA helicase CsdA, originally named DeaD because of its homology with other DEAD box proteins, has a helix-destabilizing activity. It is known to be a cold shock protein; After induction by cold shock, CsdA is ribosome associated; Plays a key role in optimal cell growth at low temperature; Suppressor of a mutant defective in rpsB gene for ribosomal protein S2; interacts with the Poly(A) polymerase; Belongs to the helicases superfamily II, DEAD/DEAH box RNA helicase family, DEAD box subfamily; Localized in the cytoplasm; High confidence in function and specificity; RNA helicase CsdA 41241 csdA 10978438 csdA Zobellia galactanivorans RNA helicase CsdA YP_004734505.1 39451 D 63186 CDS YP_004734506.1 340616053 10977684 41329..42117 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 42117 10977684 zobellia_41 Zobellia galactanivorans periplasmic protein YP_004734506.1 41329 D 63186 CDS YP_004734507.1 340616054 10976563 42168..43883 1 NC_015844.1 Alpha-amylase catalyzes the endohydrolysis of 1,4-alpha-D-glucosidic linkages in oligosaccharides and polysaccharides. Belongs to the family 13 of the glycoside hydrolases. Involved in starch metabolism. Features an uncleaved signal peptide. Localized into the cytoplasmic membrane.; High confidence in function and specificity; alpha-amylase 43883 malS 10976563 malS Zobellia galactanivorans alpha-amylase YP_004734507.1 42168 D 63186 CDS YP_004734508.1 340616055 10978121 complement(43982..44638) 1 NC_015844.1 The tRNA guanosine-2'-O-methyltransferase methylates the 2'-hydroxy group of a guanosine present in a GG sequence at position 18 of tRNAs using the S-adenosyl methionine cofactor; Contains a catalytic domain also involved in the dimer formation that adopts an alpha/beta knot fold; Localized in the cytoplasm.; High confidence in function and specificity; tRNA guanosine-2'-O-methyltransferase 44638 trmH 10978121 trmH Zobellia galactanivorans tRNA guanosine-2'-O-methyltransferase YP_004734508.1 43982 R 63186 CDS YP_004734509.1 340616056 10978690 44674..45366 1 NC_015844.1 NAD-dependent deacetylase activates the enzyme acetyl-CoA synthetase by deacetylating its catalytic Lysine in the inactive, acetylated form of the enzyme. May also modulate the activity of other propionyl-adenosine monophosphate (AMP)-forming enzymes. It binds one zinc ion as a cofactor. Localized in the cytoplasm.; High confidence in function and specificity; NAD-dependent protein deacetylase 45366 npdA 10978690 npdA Zobellia galactanivorans NAD-dependent protein deacetylase YP_004734509.1 44674 D 63186 CDS YP_004734510.1 340616057 10978264 45391..45978 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 45978 10978264 zobellia_45 Zobellia galactanivorans hypothetical protein YP_004734510.1 45391 D 63186 CDS YP_004734511.1 340616058 10976912 46083..47426 1 NC_015844.1 Adenylosuccinate lyase catalyzes step 8 in the pathway for de novo synthesis of IMP and also the final reaction in the two-step sequence from IMP to AMP. It cleaves succinylaminoimidazole carboxamide ribotide into aminoimidazole carboxamide ribotide and fumarate, as well as adenylosuccinate into adenylate and fumarate. Localized in the cytoplasm.; High confidence in function and specificity; adenylosuccinate lyase 47426 purB 10976912 purB Zobellia galactanivorans adenylosuccinate lyase YP_004734511.1 46083 D 63186 CDS YP_004734512.1 340616059 10978404 complement(47508..48323) 1 NC_015844.1 Mechanosensitive channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation; Contains three transmembrane helices; Belongs to the small-conductance MS channels; Localized in the cytoplasmic membrane; Specificity unclear; small-conductance mechanosensitive channel 48323 10978404 zobellia_47 Zobellia galactanivorans small-conductance mechanosensitive channel YP_004734512.1 47508 R 63186 CDS YP_004734513.1 340616060 10977059 complement(48469..49011) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 49011 10977059 zobellia_48 Zobellia galactanivorans lipoprotein YP_004734513.1 48469 R 63186 CDS YP_004734514.1 340616061 10977115 complement(49066..49611) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 49611 10977115 zobellia_49 Zobellia galactanivorans periplasmic protein YP_004734514.1 49066 R 63186 CDS YP_004734515.1 340616062 10977122 complement(49671..50213) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 50213 10977122 zobellia_50 Zobellia galactanivorans periplasmic protein YP_004734515.1 49671 R 63186 CDS YP_004734516.1 340616063 10977131 complement(50230..50679) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 50679 10977131 zobellia_51 Zobellia galactanivorans hypothetical protein YP_004734516.1 50230 R 63186 CDS YP_004734517.1 340616064 10977134 complement(50666..51175) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released. They alter the specificity of promoter recognition. This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors. Localized in the cytoplasm.; Family membership; RNA polymerase ECF-type sigma factor 51175 10977134 zobellia_52 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004734517.1 50666 R 63186 CDS YP_004734518.1 340616065 10977143 51415..52905 1 NC_015844.1 This peptidase is a modular protein that shows specific recognition for the C-terminal tripeptide, Xaa-Yaa-Zaa (preferably Ala or Leu, Ala or Tyr and Ala respectively). The cleavage occurs at a variable distance from the C-terminus; Contains a N-terminal domain of unknown function and a central PDZ domain involved in protein-protein interaction. In many cases, PDZ domain binds to a signature motif ([FYST]-X-[FVA]) occurring at the very C-terminus of target proteins; Belongs to the family S41 of the serine peptidases; Contains a putative lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; High confidence in function and specificity; carboxy-terminal processing peptidase 52905 10977143 zobellia_53 Zobellia galactanivorans carboxy-terminal processing peptidase YP_004734518.1 51415 D 63186 CDS YP_004734519.1 340616066 10977150 52990..54480 1 NC_015844.1 This peptidase is a modular protein that shows specific recognition for the C-terminal tripeptide, Xaa-Yaa-Zaa (preferably Ala or Leu, Ala or Tyr and Ala respectively). The cleavage occurs at a variable distance from the C-terminus; Contains a N-terminal domain of unknown function and a central PDZ domain involved in protein-protein interaction. In many cases, PDZ domain binds to a signature motif ([FYST]-X-[FVA]) occurring at the very C-terminus of target proteins; Belongs to the family S41 of the serine peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; High confidence in function and specificity; carboxy-terminal processing peptidase 54480 10977150 zobellia_54 Zobellia galactanivorans carboxy-terminal processing peptidase YP_004734519.1 52990 D 63186 CDS YP_004734520.1 340616067 10977159 complement(54556..55461) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 55461 10977159 zobellia_55 Zobellia galactanivorans hypothetical protein YP_004734520.1 54556 R 63186 CDS YP_004734521.1 340616068 10977170 complement(55494..57368) 1 NC_015844.1 BtuB protein is localized in the outer membrane and involved in the active translocation of vitamin B12 (cobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein tonB; Contains a N-terminal Plug module (46-157) acting as a channel gate. The signal peptide is cleaved between the residues 20 and 21.; High confidence in function and specificity; vitamin B12 TonB-dependent receptor 57368 btuB 10977170 btuB Zobellia galactanivorans vitamin B12 TonB-dependent receptor YP_004734521.1 55494 R 63186 CDS YP_004734522.1 340616069 10977610 complement(57741..58379) 1 NC_015844.1 Peptidyl-prolyl cis-trans isomerase, or PPIase or rotamase, accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Localized in the cytoplasm; High confidence in function and specificity; FKBP-type peptidyl-prolyl cis-trans isomerase 58379 fkpA 10977610 fkpA Zobellia galactanivorans FKBP-type peptidyl-prolyl cis-trans isomerase YP_004734522.1 57741 R 63186 CDS YP_004734523.1 340616070 10977832 58406..59554 1 NC_015844.1 Part of the ABC transporter complex btuCDF involved in vitamin B12 import. Binds cobalamin (vitamin B12) and delivers it to the periplasmic surface of btuC; Contains 1 Fe/B12 periplasmic-binding domain; belong to the TroA superfamily, btuF family; Signal peptide of lipoprotein cleaved between the residues 15 and 16; Periplasmic protein anchored in the cytoplasmic membrane; High confidence in function and specificity; vitamin B12 ABC transporter periplasmic 59554 btuF 10977832 btuF Zobellia galactanivorans vitamin B12 ABC transporter periplasmic YP_004734523.1 58406 D 63186 CDS YP_004734524.1 340616071 10977613 59555..60586 1 NC_015844.1 Part of the ABC transporter complex btuCDF involved in vitamin B12 import. The complex is composed of two ATP-binding proteins (btuD), two transmembrane proteins and a solute-binding protein (btuF); Contains nine transmembrane segments; Belongs to the periplasmic binding-protein-dependent ABC transporter family, FecCD subfamily; Localized in the cytoplasmic membrane; High confidence in function and specificity; vitamin B12 ABC transporter permease 60586 btuC 10977613 btuC Zobellia galactanivorans vitamin B12 ABC transporter permease YP_004734524.1 59555 D 63186 CDS YP_004734525.1 340616072 10977611 60729..61604 1 NC_015844.1 Conserved protein belonging to the DUF1080 family. Features a signal peptide cleaved between the residues 21 and 22. Localized in the periplasm.; Conserved hypothetical protein; hypothetical protein 61604 10977611 zobellia_60 Zobellia galactanivorans hypothetical protein YP_004734525.1 60729 D 63186 CDS YP_004734526.1 340616073 10977206 61709..62398 1 NC_015844.1 This protein is the nucleotide-binding domain (ABC ATPase) of the ABC transporter complex btuCDF involved in vitamin B12 import. It is responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Belongs to the ABC transporter family, vitamin B12 importer; Localized in the cytoplasmic membrane as a peripheral membrane protein; High confidence in function and specificity; vitamin B12 ABC transporter ATPase 62398 btuD 10977206 btuD Zobellia galactanivorans vitamin B12 ABC transporter ATPase YP_004734526.1 61709 D 63186 CDS YP_004734527.1 340616074 10977612 62464..63810 1 NC_015844.1 RmuC is involved in DNA recombination, but its exact function is unclear. It is suspected that it is either a structural protein that protects DNA against nuclease action, or is itself involved in DNA cleavage at the regions of DNA secondary structures. Localized in the cytoplasm.; Function unclear; DNA recombination protein RmuC 63810 rmuC 10977612 rmuC Zobellia galactanivorans DNA recombination protein RmuC YP_004734527.1 62464 D 63186 CDS YP_004734528.1 340616075 10978478 63807..64172 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 64172 10978478 zobellia_63 Zobellia galactanivorans periplasmic protein YP_004734528.1 63807 D 63186 CDS YP_004734529.1 340616076 10977226 64172..64717 1 NC_015844.1 Acyl-CoA thioesterase hydrolyzes fatty acyl-CoA substrates releasing acyl-Coa and fatty acids. Localized in the cytoplasm.; Specificity unclear; acyl-CoA thioesterase 64717 10977226 zobellia_64 Zobellia galactanivorans acyl-CoA thioesterase YP_004734529.1 64172 D 63186 CDS YP_004734530.1 340616077 10977236 complement(64710..65423) 1 NC_015844.1 6-Phosphogluconolactonase is the enzyme responsible for the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate, the second step of the oxidative phase of the pentose phosphate pathway; Localized in the cytoplasm; High confidence in function and specificity; 6-phosphogluconolactonase 65423 pglA 10977236 pglA Zobellia galactanivorans 6-phosphogluconolactonase YP_004734530.1 64710 R 63186 CDS YP_004734531.1 340616078 10978338 complement(65479..67011) 1 NC_015844.1 Glucose-6-phosphate 1-dehydrogenase catalyses the first step of the oxidative phase of the pentose pathway. It converts the glucose-6-phosphate to gluconolactone 6-phosphate in the presence of NADP, producing NADPH; Localized in the cytoplasm; High confidence in function and specificity; glucose-6-phosphate 1-dehydrogenase 67011 zwfA 10978338 zwfA Zobellia galactanivorans glucose-6-phosphate 1-dehydrogenase YP_004734531.1 65479 R 63186 CDS YP_004734532.1 340616079 10978796 67184..68596 1 NC_015844.1 6-Phosphogluconate dehydrogenase catalyzes the decarboxylating reduction of 6-phosphogluconate to ribulose 5-phosphate in the presence of NADP. This step is the last reaction of the oxidative phase of the pentose phosphate pathways (hexose mono-phosphate shunt); Forms a homodimer; Localized in the cytoplasm; High confidence in function and specificity; 6-phosphogluconate dehydrogenase 68596 gndA 10978796 gndA Zobellia galactanivorans 6-phosphogluconate dehydrogenase YP_004734532.1 67184 D 63186 CDS YP_004734533.1 340616080 10977939 68646..69212 1 NC_015844.1 Contains one N-terminal transmembrane segment; Probably localized in the cytoplasmic membrane; hypothetical protein 69212 10977939 zobellia_68 Zobellia galactanivorans hypothetical protein YP_004734533.1 68646 D 63186 CDS YP_004734534.1 340616081 10977250 69358..71589 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. The cytoplasmic part of the protein consists of the histidine kinase domain and of the receiver domain of the response regulator that is phosphorylated by the histidine kinase domain. A transmembrane segment separates this part from the periplasmic part that contains three tetratrico peptide repeats; Localized in the cytoplasmic membrane; Family membership; two-component system hybrid-sensor histidine kinase/response regulator, receiver domain 71589 10977250 zobellia_69 Zobellia galactanivorans two-component system hybrid-sensor histidine kinase/response regulator, receiver domain YP_004734534.1 69358 D 63186 CDS YP_004734535.1 340616082 10977257 71603..71953 1 NC_015844.1 hypothetical protein 71953 10977257 zobellia_70 Zobellia galactanivorans hypothetical protein YP_004734535.1 71603 D 63186 CDS YP_004734536.1 340616083 10977265 72037..73662 1 NC_015844.1 AlkK is involved in alkane catabolism. It catalyzes the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA. It uses ATP as cofactor; Belongs to the ATP-dependent AMP-binding enzyme family; Localized in the cytoplasm.; High confidence in function and specificity; medium-chain-fatty-acid-CoA ligase 73662 alkK 10977265 alkK Zobellia galactanivorans medium-chain-fatty-acid-CoA ligase YP_004734536.1 72037 D 63186 CDS YP_004734537.1 340616084 10977507 complement(73720..76575) 1 NC_015844.1 Carbamoyl-phosphate synthase catalyses the ATP-dependent synthesis of carbamyl-phosphate from glutamine or ammonia and bicarbonate. This important enzyme initiates both the urea cycle and the biosynthesis of arginine and/or pyrimidines. It is a heterodimer of a small and large chain. The small chain promotes the hydrolysis of glutamine to ammonia, which is used by the large chain to synthesize carbamoyl phosphate. Binds three magnesium ion as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; carbamoyl-phosphate synthase large chain 76575 carB 10977507 carB Zobellia galactanivorans carbamoyl-phosphate synthase large chain YP_004734537.1 73720 R 63186 CDS YP_004734538.1 340616085 10977623 77049..77954 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 77954 10977623 zobellia_73 Zobellia galactanivorans periplasmic protein YP_004734538.1 77049 D 63186 CDS YP_004734539.1 340616086 10977284 77960..78475 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 78475 10977284 zobellia_74 Zobellia galactanivorans membrane protein YP_004734539.1 77960 D 63186 CDS YP_004734540.1 340616087 10977293 complement(78520..80016) 1 NC_015844.1 Cardiolipin synthetase is involved in phospholipids biosynthesis. It catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (diphosphatidylglycerol) and glycerol. Contains two N-terminal transmembrane helices; Belongs to the phospholipase D family; Localized in the cytoplasmic membrane.; High confidence in function and specificity; cardiolipin synthetase 80016 clsA1 10977293 clsA1 Zobellia galactanivorans cardiolipin synthetase YP_004734540.1 78520 R 63186 CDS YP_004734541.1 340616088 10977657 complement(80115..81080) 1 NC_015844.1 Lytic murein transglycosylase catalyzes the cleavage of the beta-1,4-glycosidic bond between N- acetylmuramic acid and N-acetylglucosamine residues, thereby conserving the energy in a newly synthesized 1,6- anhydrobond in the muramic acid residue. It belongs to the family 23 of the glycoside hydrolases. May play a role in recycling of muropeptides during cell elongation and/or cell division. Features a signal peptide cleaved between the residues 23 and 24. Localized in the periplasm.; Specificity unclear; lytic murein transglycosylase 81080 10977657 zobellia_76 Zobellia galactanivorans lytic murein transglycosylase YP_004734541.1 80115 R 63186 CDS YP_004734542.1 340616089 10977300 complement(81272..81934) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 81934 10977300 zobellia_77 Zobellia galactanivorans hypothetical protein YP_004734542.1 81272 R 63186 CDS YP_004734543.1 340616090 10977304 82104..82397 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 82397 10977304 zobellia_78 Zobellia galactanivorans hypothetical protein YP_004734543.1 82104 D 63186 CDS YP_004734544.1 340616091 10977312 complement(82456..83814) 1 NC_015844.1 Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership; MiaB-like tRNA modifying protein 83814 10977312 zobellia_79 Zobellia galactanivorans MiaB-like tRNA modifying protein YP_004734544.1 82456 R 63186 CDS YP_004734545.1 340616092 10977319 complement(83926..85101) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 85101 10977319 zobellia_80 Zobellia galactanivorans hypothetical protein YP_004734545.1 83926 R 63186 CDS YP_004734546.1 340616093 10977320 complement(85239..85535) 1 NC_015844.1 Protein L31 is a part of the large subunit (50S) of the ribosome; Belongs to the ribosomal protein L31p family, type B subfamily; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L31 85535 rpmE 10977320 rpmE Zobellia galactanivorans 50S ribosomal protein L31 YP_004734546.1 85239 R 63186 CDS YP_004734547.1 340616094 10978520 complement(85836..86213) 1 NC_015844.1 Hypothetical protein containing a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the outer membrane; Hypothetical protein; hypothetical protein 86213 10978520 zobellia_82 Zobellia galactanivorans hypothetical protein YP_004734547.1 85836 R 63186 CDS YP_004734548.1 340616095 10977329 86808..87329 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 87329 10977329 zobellia_83 Zobellia galactanivorans membrane protein YP_004734548.1 86808 D 63186 CDS YP_004734549.1 340616096 10977335 87529..88503 1 NC_015844.1 ArnC catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the family 2 of the glycosyltransferase (GT2); Contains three C-terminal transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; UDP-phosphate 4-deoxy-4-formamido-L-arabinose transferase 88503 arnC1 10977335 arnC1 Zobellia galactanivorans UDP-phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_004734549.1 87529 D 63186 CDS YP_004734550.1 340616097 10977541 88543..90252 1 NC_015844.1 Phosphoglucomutase catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate. It participates in both the breakdown and synthesis of glucose. Binds one magnesium as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; phosphoglucomutase 90252 pgcA 10977541 pgcA Zobellia galactanivorans phosphoglucomutase YP_004734550.1 88543 D 63186 CDS YP_004734551.1 340616098 10978334 90252..92075 1 NC_015844.1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane; Contains six N-terminal transmembrane segments (ABC membrane) that form a pore in the cytoplasmic membrane an a C-terminal ATP-binding domain (ABC ATPase) responsible for energy generation; Belongs to the ABC-1 type transporter permease/ATP-binding family, lipid exporter subfamily (msbA subfamily); High confidence in function and specificity; lipid A export ATP-binding/permease protein 92075 msbA 10978334 msbA Zobellia galactanivorans lipid A export ATP-binding/permease protein YP_004734551.1 90252 D 63186 CDS YP_004734552.1 340616099 10978190 92134..92688 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 92688 10978190 zobellia_87 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004734552.1 92134 D 63186 CDS YP_004734553.1 340616100 10977354 92700..93215 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 93215 10977354 zobellia_88 Zobellia galactanivorans membrane protein YP_004734553.1 92700 D 63186 CDS YP_004734554.1 340616101 10977360 93208..93669 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; hypothetical protein 93669 10977360 zobellia_89 Zobellia galactanivorans hypothetical protein YP_004734554.1 93208 D 63186 CDS YP_004734555.1 340616102 10977367 complement(93682..94710) 1 NC_015844.1 Protein containing four BNR (bacterial neuraminidase repeat) repeats. These repeats are found in many glycoside hydrolases as well as other extracellular proteins of unknown function. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the outer membrane; Family membership; BNR repeat-containing protein 94710 10977367 zobellia_90 Zobellia galactanivorans BNR repeat-containing protein YP_004734555.1 93682 R 63186 CDS YP_004734556.1 340616103 10977375 94783..95994 1 NC_015844.1 RsmB specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. It uses S-adenosyl-L-methionine as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; ribosomal RNA small subunit methyltransferase B 95994 rsmB 10977375 rsmB Zobellia galactanivorans ribosomal RNA small subunit methyltransferase B YP_004734556.1 94783 D 63186 CDS YP_004734557.1 340616104 10978555 96094..99777 1 NC_015844.1 PurL is involved in purine biosynthesis. It catalyzes the conversion of formylglycinamide ribonucleotide (FGAR), glutamine, and MgATP to formylglycinamidine ribonucleotide, glutamate, ADP, and Pi. Localized in the cytoplasm.; High confidence in function and specificity; phosphoribosylformylglycinamidine synthase 99777 purL 10978555 purL Zobellia galactanivorans phosphoribosylformylglycinamidine synthase YP_004734557.1 96094 D 63186 CDS YP_004734558.1 340616105 10978411 complement(99900..102473) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 102473 10978411 zobellia_93 Zobellia galactanivorans periplasmic protein YP_004734558.1 99900 R 63186 CDS YP_004734559.1 340616106 10977393 102745..104520 1 NC_015844.1 FadD catalyzes the esterification, concomitant with transport, of exogenous long-chain fatty acids into metabolically active CoA thioesters for subsequent degradation or incorporation into phospholipids. It forms a homodimer. Localized in the cytoplasm.; High confidence in function and specificity; long-chain-fatty-acid-CoA ligase 104520 fadD 10977393 fadD Zobellia galactanivorans long-chain-fatty-acid-CoA ligase YP_004734559.1 102745 D 63186 CDS YP_004734560.1 340616107 10977813 104706..105188 1 NC_015844.1 The transcriptional regulators with the marR-type HTH domain control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents. Many of the marR-like regulators respond to aromatic compounds; Contains a DNA-binding, winged helix-turn-helix (wHTH) domain; Localized in the cytoplasm; Family membership; MarR-type transcriptional regulator 105188 10977813 zobellia_95 Zobellia galactanivorans MarR-type transcriptional regulator YP_004734560.1 104706 D 63186 CDS YP_004734561.1 340616108 10977413 105211..107616 1 NC_015844.1 Modular protein containing a N-terminal 3-Hydroxyl-CoA dehydrogenase domain and a C-terminal Enoyl-CoA hydratase domain. In Bacillus subtilis, this protein was formerly known as YusL, and has been renamed FadN by Matsuoka et al (JBC, 2007). FadN is involved in fatty acid degradation. 3-Hydroxyl-CoA dehydrogenase catalyzes the reduction of 3-hydroxyacyl-CoA to 3-oxoacyl-CoA. It uses NAD as cofactor. Enoyl-CoA hydratase catalyzes the hydratation of 2-trans-enoyl-CoA into 3-hydroxyacyl-CoA. Localized in the cytoplasm.; High confidence in function and specificity; 3-hydroxyl-CoA dehydrogenase / enoyl-CoA hydratase 107616 fadN 10977413 fadN Zobellia galactanivorans 3-hydroxyl-CoA dehydrogenase / enoyl-CoA hydratase YP_004734561.1 105211 D 63186 CDS YP_004734562.1 340616109 10977815 107661..108008 1 NC_015844.1 Bacterial 23S rRNA proteins are a proteins encoded within an intervening sequence present within some 23S rRNA genes; The function of these proteins is not known; 23S ribosomal protein forms a homopentamer; Localized in the cytoplasm; Family membership; 23S ribosomal protein 108008 10977815 zobellia_97 Zobellia galactanivorans 23S ribosomal protein YP_004734562.1 107661 D 63186 CDS YP_004734563.1 340616110 10977428 108048..109238 1 NC_015844.1 3-Ketoacyl-CoA thiolase, also known as acetyl-CoA C-acyltransferase, has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid beta-oxidation. It catalyzes the reaction: Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA. Localized in the cytoplasm.; High confidence in function and specificity; 3-Ketoacyl-CoA thiolase 109238 fadA 10977428 fadA Zobellia galactanivorans 3-Ketoacyl-CoA thiolase YP_004734563.1 108048 D 63186 CDS YP_004734564.1 340616111 10977812 109269..111065 1 NC_015844.1 Acyl-CoA dehydrogenase is involved in fatty acid degradation. It catalyzes the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3- enoyl CoA-products with concommitant reduction of enzyme- bound FAD. In Bacillus subtilis, this protein, formerly known as yusJ protein, has been renamed FadE by Matsuoka et al (JBC, 2007). Localized in the cytoplasm.; Specificity unclear; acyl-CoA dehydrogenase 111065 fadE 10977812 fadE Zobellia galactanivorans acyl-CoA dehydrogenase YP_004734564.1 109269 D 63186 CDS YP_004734565.1 340616112 10977814 complement(111146..112948) 1 NC_015844.1 Glycoside hydrolases hydrolyse the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non-carbohydrate moiety. This enzyme belongs to the family 15 of the glycoside hydrolases. Localized in the cytoplasm.; Specificity unclear; glycoside hydrolase 112948 10977814 zobellia_100 Zobellia galactanivorans glycoside hydrolase YP_004734565.1 111146 R 63186 CDS YP_004734566.1 340616113 10974061 113051..115261 1 NC_015844.1 This enzyme is involved in the biosynthesis of trehalose. It is a fusion protein between the trehalose-6-phosphate synthase (OtsA) and the trehalose-6-phosphate phosphatase (OtsB). Trehalose-6-phosphate synthase catalyzes the reaction: UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate. It belongs to the family 20 of the glycosyltransferases (GT20). trehalose-6-phosphate phosphatase catalyzes the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate. Localized in the cytoplasm.; High confidence in function and specificity; Trehalose-6-phosphate synthase/phosphatase, family GT20 115261 otsAB 10974061 otsAB Zobellia galactanivorans Trehalose-6-phosphate synthase/phosphatase, family GT20 YP_004734566.1 113051 D 63186 CDS YP_004734567.1 340616114 10978289 115550..116725 1 NC_015844.1 The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Features twelve transmembrane helices. Localized in the cytoplasmic membrane.; Family membership; major facilitator family transporter 116725 10978289 zobellia_102 Zobellia galactanivorans major facilitator family transporter YP_004734567.1 115550 D 63186 CDS YP_004734568.1 340616115 10974077 116830..118188 1 NC_015844.1 Protein that could be involved in ATP-dependent RNA unwinding in a variety of cellular processes, including ribosome assembly, protein synthesis, and RNA degradation; Contains a DEAD box; Belongs to the helicases superfamily II, DEAD/DEAH box RNA helicase family, DEAD box subfamily; Localized in the cytoplasm; Family membership; DEAD/DEAH RNA helicase 118188 10974077 zobellia_103 Zobellia galactanivorans DEAD/DEAH RNA helicase YP_004734568.1 116830 D 63186 CDS YP_004734569.1 340616116 10974086 118313..119926 1 NC_015844.1 Aminopeptidase catalyzes the hydrolysis of N-terminal amino-acid residues from oligopeptides or polypeptides. This enzyme belongs to the family M1 of the peptidases. A catalytic zinc ion is bound by two histidines and a glutamate. The histidines are within an 'HEXXH' motif on one long helix with the glutamate on another antiparallel helix. The catalytic mechanism is believed to involve activation of a water molecule by the zinc ion. The glutamate of the HEXXH motif is known to be important for catalysis and a tyrosine may also be involved. Features a signal peptide cleaved between the residues 18 and 19. Localized in the periplasm.; Specificity unclear; aminopeptidase 119926 10974086 zobellia_104 Zobellia galactanivorans aminopeptidase YP_004734569.1 118313 D 63186 CDS YP_004734570.1 340616117 10974097 complement(120004..123039) 1 NC_015844.1 Protein that contains a N-terminal domain of about 740 residues whithout any similarity then, in the C-terminal part a PKD domain and a C-type cytochrome domain are present; Lipoprotein with a signal peptide cleaved between the residues 18 and 19, Localized in the cytoplasmic or outer membrane (or both); Conserved hypothetical protein; lipoprotein 123039 10974097 zobellia_105 Zobellia galactanivorans lipoprotein YP_004734570.1 120004 R 63186 CDS YP_004734571.1 340616118 10974101 123219..123812 1 NC_015844.1 Methyltransferase using S-adenosylmethionine as cofactor. Its exact function is unknown. Localized in the cytoplasm.; Function unclear; SAM-dependent methyltransferase 123812 10974101 zobellia_106 Zobellia galactanivorans SAM-dependent methyltransferase YP_004734571.1 123219 D 63186 CDS YP_004734572.1 340616119 10974111 complement(123828..124205) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 124205 10974111 zobellia_107 Zobellia galactanivorans hypothetical protein YP_004734572.1 123828 R 63186 CDS YP_004734573.1 340616120 10974120 124545..125348 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 125348 10974120 zobellia_108 Zobellia galactanivorans lipoprotein YP_004734573.1 124545 D 63186 CDS YP_004734574.1 340616121 10974131 125410..126456 1 NC_015844.1 Di-heme cytochrome c peroxidase (CCP) reduces hydrogen peroxide to water using c-type heme as an oxidizable substrate. However, since it possesses two, instead of one, heme prosthetic groups, CCPs reduce hydrogen peroxide without the need to generate semi-stable free radicals. The two heme groups have significantly different redox potentials. CCP is structured into two domains, each containing one c-type haem group, with a calcium-binding site at the domain interface. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the cytoplasmic membrane; High confidence in function and specificity; di-heme cytochrome c peroxidase 126456 ccpA1 10974131 ccpA1 Zobellia galactanivorans di-heme cytochrome c peroxidase YP_004734574.1 125410 D 63186 CDS YP_004734575.1 340616122 10977635 126431..127450 1 NC_015844.1 Contains a signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 127450 10977635 zobellia_110 Zobellia galactanivorans periplasmic protein YP_004734575.1 126431 D 63186 CDS YP_004734576.1 340616123 10974151 127665..128360 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 128360 30288 10974151 30288 Zobellia galactanivorans periplasmic protein YP_004734576.1 127665 D 63186 CDS YP_004734577.1 340616124 10977454 128400..129620 1 NC_015844.1 Protein containing a N-terminal serine peptidase of the family S9 and and a C-terminal OsmC domain involved in the osmotic stress. The active site residues of family S9 serine peptidases are in the order Ser, Asp, His in the sequence. Localized in the cytoplasm.; Specificity unclear; serine peptidase 129620 10977454 zobellia_112 Zobellia galactanivorans serine peptidase YP_004734577.1 128400 D 63186 CDS YP_004734578.1 340616125 10974169 129752..130390 1 NC_015844.1 Protein containing a putative lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 130390 10974169 zobellia_113 Zobellia galactanivorans membrane protein YP_004734578.1 129752 D 63186 CDS YP_004734579.1 340616126 10974177 130593..131198 1 NC_015844.1 Superoxide dismutase destroys radicals which are normally produced by the cells and which are toxic to biological systems. It catalyzes the dismutation of superoxide into molecular oxygen and hydrogen peroxide. It forms a homodimer and binds one iron and one copper ion as cofactors per subunit; Contains a putative lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; High confidence in function and specificity; superoxide dismutase 131198 sodC 10974177 sodC Zobellia galactanivorans superoxide dismutase YP_004734579.1 130593 D 63186 CDS YP_004734580.1 340616127 10978602 complement(131282..132382) 1 NC_015844.1 Conserved protein belonging to the bacterial surface antigen family, which includes D15 antigen from H. influenzae, OMA87 from P.multocida, OMP85 from N. meningitidis and N.gonorrhoeae. Features a signal peptide cleaved between the residues 22 and 23. Predicted to be Localized in the outer membrane.; Function unclear; surface antigen 132382 10978602 zobellia_115 Zobellia galactanivorans surface antigen YP_004734580.1 131282 R 63186 CDS YP_004734581.1 340616128 10974195 133535..134728 1 NC_015844.1 Contains one C-terminal transmembrane helix. Localized in the cytoplasmic membrane.; Conserved hypothetical protein; membrane protein 134728 10974195 zobellia_116 Zobellia galactanivorans membrane protein YP_004734581.1 133535 D 63186 CDS YP_004734582.1 340616129 10974203 complement(134809..135564) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, that acts as transcriptional regulator; Family membership; two-component system-response regulator 135564 10974203 zobellia_117 Zobellia galactanivorans two-component system-response regulator YP_004734582.1 134809 R 63186 CDS YP_004734583.1 340616130 10974210 complement(135595..135933) 1 NC_015844.1 Contains two transmembrane segments; Probably localized in the cytoplasmic membrane; hypothetical protein 135933 10974210 zobellia_118 Zobellia galactanivorans hypothetical protein YP_004734583.1 135595 R 63186 CDS YP_004734584.1 340616131 10974213 complement(135974..136267) 1 NC_015844.1 Contains two transmembrane segments; Probably localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 136267 10974213 zobellia_119 Zobellia galactanivorans membrane protein YP_004734584.1 135974 R 63186 CDS YP_004734585.1 340616132 10974218 complement(136413..137756) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains four and two transmembrane segments in the N- and C- terminal domain respectively; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 137756 10974218 zobellia_120 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004734585.1 136413 R 63186 CDS YP_004734586.1 340616133 10974226 complement(137883..138344) 1 NC_015844.1 The AsnC/Lrp-type transcriptional regulator family appears to be an important regulatory system of the amino acid metabolism and related processes; Contains a N-terminal DNA binding AsnC/Lrp-type HTH domain. The C-terminal part contains an effector-binding domain and/or an oligomerization domain; Localized in the cytoplasm; Family membership; AsnC/Lrp-type transcriptional regulator 138344 10974226 zobellia_121 Zobellia galactanivorans AsnC/Lrp-type transcriptional regulator YP_004734586.1 137883 R 63186 CDS YP_004734587.1 340616134 10974234 138504..140828 1 NC_015844.1 The vitamin-B12 independent methionine synthase catalyzes the last step in the production of methionine by transferring a methyl group from 5-methyltetrahydrofolate to homocysteine. It binds one zinc ion as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 140828 metE 10974234 metE Zobellia galactanivorans 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase YP_004734587.1 138504 D 63186 CDS YP_004734588.1 340616135 10978149 140915..142468 1 NC_015844.1 Conserved FAD-dependent oxidoreductase. Its exact specificity is unknown. Localized in the cytoplasm.; Specificity unclear; FAD-dependent oxidoreductase 142468 10978149 zobellia_123 Zobellia galactanivorans FAD-dependent oxidoreductase YP_004734588.1 140915 D 63186 CDS YP_004734589.1 340616136 10974250 142525..143826 1 NC_015844.1 The ATP-dependent RNA helicase RhlE interacts with the Poly(A) polymerase. It is nonessential for bacterial cell growth; Belongs to the helicases superfamily II, DEAD/DEAH box RNA helicase family, DEAD box subfamily; Localized in the cytoplasm; High confidence in function and specificity; RNA helicase RhlE 143826 rhlE 10974250 rhlE Zobellia galactanivorans RNA helicase RhlE YP_004734589.1 142525 D 63186 CDS YP_004734590.1 340616137 10978456 complement(143823..144017) 1 NC_015844.1 Hypothetical protein; hypothetical protein 144017 10978456 zobellia_125 Zobellia galactanivorans hypothetical protein YP_004734590.1 143823 R 63186 CDS YP_004734591.1 340616138 10974256 144026..144859 1 NC_015844.1 The Endonuclease/exonuclease/phosphatase domain is found in a large number of proteins including magnesium dependent endonucleases and phosphatases involved in intracellular signalling; Belongs to the Endonuclease/Exonuclease/ phosphatase family; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Family membership; endonuclease/exonuclease/phosphatase family protein 144859 10974256 zobellia_126 Zobellia galactanivorans endonuclease/exonuclease/phosphatase family protein YP_004734591.1 144026 D 63186 CDS YP_004734592.1 340616139 10974263 complement(144927..145757) 1 NC_015844.1 Haloperoxidase acting with chlore or bromide ions; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine and to the bacterial non-heme bromo- and chloro-peroxidases family; Localized in the cytoplasm; Specificity unclear; Non-heme haloperoxidase 145757 10974263 zobellia_127 Zobellia galactanivorans Non-heme haloperoxidase YP_004734592.1 144927 R 63186 CDS YP_004734593.1 340616140 10974274 145898..146503 1 NC_015844.1 PaiB is a transcriptional regulator with a helix-turn-helix domain and a FMN-binding domain. In Bacillus subtilis, PaiB is Involved in the reduction of extracellular and cell-associated protease levels, as well as in the reduced levels of alpha-amylase, levansucrase, alkaline phosphatase and sporulation inhibition, when present in high copy number.; High confidence in function and specificity; transcriptional regulator PaiB 146503 paiB 10974274 paiB Zobellia galactanivorans transcriptional regulator PaiB YP_004734593.1 145898 D 63186 CDS YP_004734594.1 340616141 10978296 complement(146512..147531) 1 NC_015844.1 Conserved protein belonging to the NAD(P)-dependent sugar epimerase/dehydratase family, which is included in the Rossmann fold Superfamily. Localized in the cytoplasm.; Specificity unclear; NAD(P)-dependent sugar epimerase/dehydratase 147531 10978296 zobellia_129 Zobellia galactanivorans NAD(P)-dependent sugar epimerase/dehydratase YP_004734594.1 146512 R 63186 CDS YP_004734595.1 340616142 10974292 complement(147750..148229) 1 NC_015844.1 DspA protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction; Forms a homododecamer and the 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited; Localized in the cytoplasm; High confidence in function and specificity; DNA protection during starvation protein 148229 dpsA1 10974292 dpsA1 Zobellia galactanivorans DNA protection during starvation protein YP_004734595.1 147750 R 63186 CDS YP_004734596.1 340616143 10977762 148337..149275 1 NC_015844.1 Transcriptional regulator belonging to the LysR family. Features a N-terminal helix-turn-helix DNA binding domain and a C-terminal LysR-like substrate binding domain. Localized in the cytoplasm.; Specificity unclear; LysR family transcriptional regulator 149275 10977762 zobellia_131 Zobellia galactanivorans LysR family transcriptional regulator YP_004734596.1 148337 D 63186 CDS YP_004734597.1 340616144 10974306 complement(149359..149544) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 149544 10974306 zobellia_132 Zobellia galactanivorans hypothetical protein YP_004734597.1 149359 R 63186 CDS YP_004734598.1 340616145 10974311 149679..150971 1 NC_015844.1 D-alanyl-D-alanine carboxypeptidase, also known as Penicillin-binding protein 4, is involved in the peptidoglycan biosynthesis. It hydrolyzes the D-Ala-D-Ala bond in the cross-linking peptide precursor, and performs the transpeptidation reaction between the D-Ala and the meso-2,6-diaminopimelate of adjacent crosslinking peptides of the bacterial cell wall; Belongs to the family S13 of the serine peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 27 and 28; Localized in the outer membrane; High confidence in function and specificity; D-alanyl-D-alanine carboxypeptidase 150971 dacB 10974311 dacB Zobellia galactanivorans D-alanyl-D-alanine carboxypeptidase YP_004734598.1 149679 D 63186 CDS YP_004734599.1 340616146 10977712 complement(150995..151579) 1 NC_015844.1 This family of proteins catalyses the hydrolysis of phosphorus-containing acid anhydrides such as nucleoside diphosphate, for example ADP-mannose and UDP-glucose; Protein that consists of a NUDIX hydrolases (NUcleoside DIphosphate linked to some other moiety X) domain; Localized in the cytoplasm; Family membership; nucleoside diphosphate pyrophosphatase 151579 10977712 zobellia_134 Zobellia galactanivorans nucleoside diphosphate pyrophosphatase YP_004734599.1 150995 R 63186 CDS YP_004734600.1 340616147 10974326 complement(151635..152054) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity that acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership; two-component system-response regulator, receiver domain 152054 10974326 zobellia_135 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004734600.1 151635 R 63186 CDS YP_004734601.1 340616148 10974337 complement(152152..152808) 1 NC_015844.1 Protein localized in the cytoplasm; hypothetical protein 152808 10974337 zobellia_136 Zobellia galactanivorans hypothetical protein YP_004734601.1 152152 R 63186 CDS YP_004734602.1 340616149 10974343 complement(152874..153671) 1 NC_015844.1 Protein that consists of a domain of unknown function (DUF124), Localized in the cytoplasm; hypothetical protein 153671 10974343 zobellia_137 Zobellia galactanivorans hypothetical protein YP_004734602.1 152874 R 63186 CDS YP_004734603.1 340616150 10974351 complement(153746..154249) 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 154249 10974351 zobellia_138 Zobellia galactanivorans hypothetical protein YP_004734603.1 153746 R 63186 CDS YP_004734604.1 340616151 10974356 154335..154814 1 NC_015844.1 Contains three transmembrane segments; Probably localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 154814 10974356 zobellia_139 Zobellia galactanivorans membrane protein YP_004734604.1 154335 D 63186 CDS YP_004734605.1 340616152 10974363 154814..155266 1 NC_015844.1 Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 155266 10974363 zobellia_140 Zobellia galactanivorans periplasmic protein YP_004734605.1 154814 D 63186 CDS YP_004734606.1 340616153 10974375 155410..155811 1 NC_015844.1 Transcriptional regulator belonging to the PadR family. Features a helix-turn-helix DNA binding motif. Localized in the cytoplasm.; Specificity unclear; PadR-type transcriptional regulator 155811 10974375 zobellia_141 Zobellia galactanivorans PadR-type transcriptional regulator YP_004734606.1 155410 D 63186 CDS YP_004734607.1 340616154 10974383 155876..157717 1 NC_015844.1 Contains a PspC domain that is thought to be a stress-responsive transcriptional regulator, and four transmembrane segments; Probably localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 157717 10974383 zobellia_142 Zobellia galactanivorans hypothetical protein YP_004734607.1 155876 D 63186 CDS YP_004734608.1 340616155 10974389 157839..158570 1 NC_015844.1 Signal peptide cleaved between the residues 19 and 20; localized in the outer or cytoplasmic membrane or both; Hypothetical protein; hypothetical protein 158570 10974389 zobellia_143 Zobellia galactanivorans hypothetical protein YP_004734608.1 157839 D 63186 CDS YP_004734609.1 340616156 10974397 158733..159746 1 NC_015844.1 L-alanine-DL-glutamate epimerase catalyzes the epimerization of D-Glu into L-Glu, in the context of the dipeptide L-Ala-D-Glu, which is a component of peptidoglycan. Involved in peptidoglycan metabolism. This enzyme belongs to the Mandelate racemase / muconate lactonizing enzyme family. These enzymes feature a N-terminal domain with a Enolase N-terminal domain-like fold and a C-terminal TIM alpha/beta barrel fold. Localized in the cytoplasm.; High confidence in function and specificity; L-alanine-DL-glutamate epimerase 159746 10974397 zobellia_144 Zobellia galactanivorans L-alanine-DL-glutamate epimerase YP_004734609.1 158733 D 63186 CDS YP_004734610.1 340616157 10974407 159743..160786 1 NC_015844.1 Aminotransferases are enzymes that catalysis the transfer of a nitrogenous group from one compound (donor) to another (acceptor) using pyridoxal-phosphate group, bound to a lysine residue, as cofactor; Localized in the cytoplasm; Family membership; class II aminotransferase 160786 10974407 zobellia_145 Zobellia galactanivorans class II aminotransferase YP_004734610.1 159743 D 63186 CDS YP_004734611.1 340616158 10974412 complement(160802..162280) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 17 and 18; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 162280 10974412 zobellia_146 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734611.1 160802 R 63186 CDS YP_004734612.1 340616159 10974420 complement(162292..165447) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (20-93) and the Plug module (110-246) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 165447 10974420 zobellia_147 Zobellia galactanivorans TonB-dependent Receptor YP_004734612.1 162292 R 63186 CDS YP_004734613.1 340616160 10974427 165551..165703 1 NC_015844.1 Hypothetical protein; hypothetical protein 165703 10974427 zobellia_148 Zobellia galactanivorans hypothetical protein YP_004734613.1 165551 D 63186 CDS YP_004734614.1 340616161 10974436 165743..166162 1 NC_015844.1 Localized in the cytoplas; hypothetical protein 166162 10974436 zobellia_149 Zobellia galactanivorans hypothetical protein YP_004734614.1 165743 D 63186 CDS YP_004734615.1 340616162 10974445 166243..166689 1 NC_015844.1 Contains an uncleaved signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 166689 10974445 zobellia_150 Zobellia galactanivorans membrane protein YP_004734615.1 166243 D 63186 CDS YP_004734616.1 340616163 10974453 complement(166757..167722) 1 NC_015844.1 The active site of this enzyme is a redox-active disulfide bond. TrxB uses the FAD to shuttle reducing equivalents from NAD(P)H to a Cys residue that is usually a part of a redox-active disulphide bridge. In a second step, the reduced disulphide reduces the substrate; Acts as an homodimer and binds one FAD molecule per subunit; Belongs to the class 2 of the pyridine nucleotide- disulphide reductases (PNDR); Localized in the cytoplasm; High confidence in function and specificity; thioredoxin reductase 167722 trxB1 10974453 trxB1 Zobellia galactanivorans thioredoxin reductase YP_004734616.1 166757 R 63186 CDS YP_004734617.1 340616164 10978709 complement(168043..168888) 1 NC_015844.1 Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains one N-terminal copy of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS-box proteins and bind to DNA; Localized in the cytoplasm; Family membership; universal stress protein 168888 10978709 zobellia_152 Zobellia galactanivorans universal stress protein YP_004734617.1 168043 R 63186 CDS YP_004734618.1 340616165 10974466 169150..169854 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity (here a LytTR-type HTH domain), which acts as transcriptional regulator; Family membership; two-component system-response regulator 169854 10974466 zobellia_153 Zobellia galactanivorans two-component system-response regulator YP_004734618.1 169150 D 63186 CDS YP_004734619.1 340616166 10974473 complement(169910..171040) 1 NC_015844.1 Involved in the first step of galactose metabolism that catalyzes the D-galactose to alpha-D-galactose-1-phosphate; Localized in the cytoplasm; High confidence in function and specificity; galactokinase 171040 galK 10974473 galK Zobellia galactanivorans galactokinase YP_004734619.1 169910 R 63186 CDS YP_004734620.1 340616167 10977876 complement(171047..172192) 1 NC_015844.1 Converts newly synthesized inactive sulfatases to their active form by modifying an active site cysteine or serine residue to 3-oxoalanine; Putatively localized in the outer membrane; Specificity unclear; C-alpha-formylglycine-generating protein 172192 fgeA 10977876 fgeA Zobellia galactanivorans C-alpha-formylglycine-generating protein YP_004734620.1 171047 R 63186 CDS YP_004734621.1 340616168 10977830 complement(172339..173679) 1 NC_015844.1 Exo-alpha-sialidase catalyzes the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. Features a twin-arginine signal peptide. Localized in the periplasm.; High confidence in function and specificity; exo-alpha-sialidase 173679 siaHI 10977830 siaHI Zobellia galactanivorans exo-alpha-sialidase YP_004734621.1 172339 R 63186 CDS YP_004734622.1 340616169 10978596 174180..175430 1 NC_015844.1 The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients; Contains 11 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; major facilitator family transporter 175430 10978596 zobellia_157 Zobellia galactanivorans major facilitator family transporter YP_004734622.1 174180 D 63186 CDS YP_004734623.1 340616170 10974510 175877..178912 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (26-100) and the Plug module (116-221) acting as a channel gate; The signal peptide is cleaved between the residues 23 and 24; Family membership; TonB-dependent Receptor 178912 10974510 zobellia_158 Zobellia galactanivorans TonB-dependent Receptor YP_004734623.1 175877 D 63186 CDS YP_004734624.1 340616171 10974519 178924..180411 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 180411 10974519 zobellia_159 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734624.1 178924 D 63186 CDS YP_004734625.1 340616172 10974524 180535..183843 1 NC_015844.1 ASPIC and UnbV sequences are found associated with tetratrico peptide repeat in several paralogous proteins in Rhodopirellula baltica and with FG-GAP repeats in several eukaryotic integrin-like proteins and in several other bacterial proteins; The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding; The FG-GAP repeat has been predicted to fold into a beta propeller structure; Contain a uncleavable signal peptide that Would localizes the protein in the cytoplasmic membrane; Function unclear; ASPIC/UnbV-like protein 183843 10974524 zobellia_160 Zobellia galactanivorans ASPIC/UnbV-like protein YP_004734625.1 180535 D 63186 CDS YP_004734626.1 340616173 10974532 complement(183830..183925) 1 NC_015844.1 Hypothetical protein; hypothetical protein 183925 10974532 zobellia_161 Zobellia galactanivorans hypothetical protein YP_004734626.1 183830 R 63186 CDS YP_004734627.1 340616174 10974539 complement(183900..184916) 1 NC_015844.1 Enzyme that hydrolyzes the beta-1,4-D-xylans linkage, to remove successive D-xylose residues from the non-reducing termini; Belongs to the family 43 of the glycoside hydrolase (GH43); Protein localized in the cytoplasm; High confidence in function and specificity; beta-xylosidase 184916 xylB 10974539 xylB Zobellia galactanivorans beta-xylosidase YP_004734627.1 183900 R 63186 CDS YP_004734628.1 340616175 10978766 complement(184943..186400) 1 NC_015844.1 These integral membrane proteins mediate the intake of a wide variety of molecules with the concomitant uptake of sodium ions (sodium symporters); Belongs to the sodium:galactoside symporter family; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; sugar transport protein 186400 xylP 10978766 xylP Zobellia galactanivorans sugar transport protein YP_004734628.1 184943 R 63186 CDS YP_004734629.1 340616176 10978768 complement(186407..187546) 1 NC_015844.1 Enzyme that endohydrolyzes the beta-1,4-D-xylosidic linkages in xylans; Belongs to the family 10 of glycoside hydrolase (GH10); The signal peptide is cleaved between the residues 17 and 18; This sequence is a lipoporotein putatively localized in the outer membrane; High confidence in function and specificity; endo-beta-1,4-glucanase 187546 xylA 10978768 xylA Zobellia galactanivorans endo-beta-1,4-glucanase YP_004734629.1 186407 R 63186 CDS YP_004734630.1 340616177 10978764 complement(187844..188323) 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 188323 10978764 zobellia_165 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004734630.1 187844 R 63186 CDS YP_004734631.1 340616178 10974567 188472..188573 1 NC_015844.1 Hypothetical protein; hypothetical protein 188573 10974567 zobellia_166 Zobellia galactanivorans hypothetical protein YP_004734631.1 188472 D 63186 CDS YP_004734632.1 340616179 10974575 complement(188622..189371) 1 NC_015844.1 CAAX prenyl peptidase removes a AAX tripeptide from the C-terminal CAAX motif of a protein when a prenyl group is attached to the Cys residue. Putatively involved in protein modification and secretion or/and in the bacteriophage resistance. Belongs to the family U48 of the peptidases. The catalytic mechanism is still unknown. Contains five transmembrane segments. Protein localized in the cytoplasmic membrane.; Family membership; CAAX prenyl peptidase 189371 10974575 zobellia_167 Zobellia galactanivorans CAAX prenyl peptidase YP_004734632.1 188622 R 63186 CDS YP_004734633.1 340616180 10974582 complement(189675..190175) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 190175 10974582 zobellia_168 Zobellia galactanivorans hypothetical protein YP_004734633.1 189675 R 63186 CDS YP_004734634.1 340616181 10974592 complement(190318..194457) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 194457 10974592 zobellia_169 Zobellia galactanivorans one-component system sensor protein YP_004734634.1 190318 R 63186 CDS YP_004734635.1 340616182 10974601 complement(194611..195105) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 195105 10974601 zobellia_170 Zobellia galactanivorans periplasmic protein YP_004734635.1 194611 R 63186 CDS YP_004734636.1 340616183 10974610 complement(195354..196010) 1 NC_015844.1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. It catalyzes the reversible transfer of a three-carbon ketol unit from sedoheptulose 7-phosphate to glyceraldehyde 3-phosphate to form erythrose 4-phosphate and fructose 6-phosphate. This enzyme, together with transketolase, provides a link between the Embden-Meyerhof pathway and the non-oxidative phase of pentose-phosphate pathway; Localized in the cytoplasm; High confidence in function and specificity; transaldolase 196010 talA1 10974610 talA1 Zobellia galactanivorans transaldolase YP_004734636.1 195354 R 63186 CDS YP_004734637.1 340616184 10978636 complement(196022..197347) 1 NC_015844.1 Xylose isomerase is involved in xylose metabolism. It catalyzes the conversion of D-xylose into D-xylulose. It forms a homotetramer and binds 2 magnesium ions per subunit. Localized in the cytoplasm.; High confidence in function and specificity; Xylose isomerase 197347 xylA 10978636 xylA Zobellia galactanivorans Xylose isomerase YP_004734637.1 196022 R 63186 CDS YP_004734638.1 340616185 10978765 complement(197349..198833) 1 NC_015844.1 Xylulose kinase is involved in xylose catabolism. It catalyzes the reaction: ATP + D-xylulose = ADP + D-xylulose 5-phosphate. Localized in the cytoplasm.; High confidence in function and specificity; xylulose kinase 198833 xylB 10978765 xylB Zobellia galactanivorans xylulose kinase YP_004734638.1 197349 R 63186 CDS YP_004734639.1 340616186 10978767 199166..200191 1 NC_015844.1 The LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of operons; They contain a N-terminal lacI-type HTH domain involved in the binding of the protein to the operator sequences in the DNA and a C- terminal periplasmic binding protein domain that are the primary receptors for chemotaxis and transport of many sugar based solutes that act as inducers; Localized in the cytoplasm; Family membership; LacI-type transcriptional regulator 200191 10978767 zobellia_174 Zobellia galactanivorans LacI-type transcriptional regulator YP_004734639.1 199166 D 63186 CDS YP_004734640.1 340616187 10974637 complement(200205..202310) 1 NC_015844.1 Contains five transmembrane helices in the N-terminal region; Contains a central motif reminiscent of the Planctomycete cytochrome C motif; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 202310 10974637 zobellia_175 Zobellia galactanivorans membrane protein YP_004734640.1 200205 R 63186 CDS YP_004734641.1 340616188 10974641 complement(202315..203769) 1 NC_015844.1 Protein containing a domain of unknown function DUF1501; Belongs to the alkaline-phosphatase clan; Contains a twin-arginine signal peptide; Localized in the periplasmic space; Family membership; periplasmic protein 203769 10974641 zobellia_176 Zobellia galactanivorans periplasmic protein YP_004734641.1 202315 R 63186 CDS YP_004734642.1 340616189 10974651 complement(203786..206089) 1 NC_015844.1 This protein has a modular architecture with a N-terminal cytochrome C and two domains of unknown function, a DUF1549 domain which includes a second cytochrome C and a C-terminal DUF1553 domain. Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes. Contains a putative lipoprotein signal peptide cleaved between the residues 17 and 18; Possibly localized in the outer membrane; Function unclear; cytochrome c-containing protein 206089 10974651 zobellia_177 Zobellia galactanivorans cytochrome c-containing protein YP_004734642.1 203786 R 63186 CDS YP_004734643.1 340616190 10974661 complement(206093..207148) 1 NC_015844.1 This protein likely adopts a beta-propeller fold; Contains a twin-arginine signal peptide; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 207148 10974661 zobellia_178 Zobellia galactanivorans periplasmic protein YP_004734643.1 206093 R 63186 CDS YP_004734644.1 340616191 10974668 complement(207267..211181) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains a transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 211181 10974668 zobellia_179 Zobellia galactanivorans one-component system sensor protein YP_004734644.1 207267 R 63186 CDS YP_004734645.1 340616192 10974674 complement(211202..211351) 1 NC_015844.1 Hypothetical protein; hypothetical protein 211351 10974674 zobellia_180 Zobellia galactanivorans hypothetical protein YP_004734645.1 211202 R 63186 CDS YP_004734646.1 340616193 10974684 211464..213113 1 NC_015844.1 Iduronate-2-sulfatase, called also Chondroitinsulfatase is involved in the glycosaminoglycan degradation. It hydrolyzes the 2-sulfate groups from non-reducing-terminal iduronic acid residues in dermatan sulfate and heparan sulfate and heparin; Belongs to the family 1 of sulfatases (formylglycine-dependent sulfatases), subfamily 7; Putative lipoprotein with a signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; High confidence in function and specificity; iduronate-2-sulfatase 213113 idsA1 10974684 idsA1 Zobellia galactanivorans iduronate-2-sulfatase YP_004734646.1 211464 D 63186 CDS YP_004734647.1 340616194 10978024 complement(213110..213229) 1 NC_015844.1 Hypothetical protein; hypothetical protein 213229 10978024 zobellia_182 Zobellia galactanivorans hypothetical protein YP_004734647.1 213110 R 63186 CDS YP_004734648.1 340616195 10974698 213322..215040 1 NC_015844.1 FAD-dependent oxidoreductase, Belongs to the GMC oxidoreductase family; Localized in the cytoplasm; Specificity unclear; FAD-dependent oxidoreductase 215040 10974698 zobellia_183 Zobellia galactanivorans FAD-dependent oxidoreductase YP_004734648.1 213322 D 63186 CDS YP_004734649.1 340616196 10974703 215047..215766 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 23 and 24; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 215766 10974703 zobellia_184 Zobellia galactanivorans membrane protein YP_004734649.1 215047 D 63186 CDS YP_004734650.1 340616197 10974708 complement(215864..217075) 1 NC_015844.1 Conserved hypothetical protein; Lipoprotein signal peptide cleaved between the residues 24 and 25; localized in the cytoplasmic or/and outer membrane; hypothetical protein 217075 10974708 zobellia_185 Zobellia galactanivorans hypothetical protein YP_004734650.1 215864 R 63186 CDS YP_004734651.1 340616198 10974715 complement(217197..219137) 1 NC_015844.1 Contains a putaive lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 219137 10974715 zobellia_186 Zobellia galactanivorans membrane protein YP_004734651.1 217197 R 63186 CDS YP_004734652.1 340616199 10974723 complement(219196..220449) 1 NC_015844.1 The Sugar permeases belong to the major facilitator superfamily (MFS) transporters that are single-polypeptide secondary carriers capable only of transporting small solutes (probably sugars in this case) in response to chemiosmotic ion gradients; Contains 11 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; sugar permease 220449 10974723 zobellia_187 Zobellia galactanivorans sugar permease YP_004734652.1 219196 R 63186 CDS YP_004734653.1 340616200 10974731 complement(220474..221274) 1 NC_015844.1 Also called 5-keto-D-gluconate 5-reductase; Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate using NADP as a coenzyme. Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity; gluconate-5-dehydrogenase 221274 idnO1 10974731 idnO1 Zobellia galactanivorans gluconate-5-dehydrogenase YP_004734653.1 220474 R 63186 CDS YP_004734654.1 340616201 10978020 complement(221278..222123) 1 NC_015844.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase is Involved in pectin degradation in pectinolytic microorganism; Localized in the cytoplasm; High confidence in function and specificity; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 222123 kduI1 10978020 kduI1 Zobellia galactanivorans 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase YP_004734654.1 221278 R 63186 CDS YP_004734655.1 340616202 10978062 complement(222131..223282) 1 NC_015844.1 This protein belongs to the family 105 of the glycoside hydrolases. These enzymes are involved in the catabolism of unsaturated oligosaccharides produced by polysaccharide lyases. Asp104 is the putative catalytic residue (identical to Asp143 of the unsaturated rhamnogalacturonyl hydrolase from Bacillus subtilis, Itoh et al., 2006, BBRC 347, 10211029). Features a signal peptide cleaved between residues 20 and 21. Localized in the periplasm.; Specificity unclear; glycoside hydrolase 223282 10978062 zobellia_190 Zobellia galactanivorans glycoside hydrolase YP_004734655.1 222131 R 63186 CDS YP_004734656.1 340616203 10974759 complement(223417..225111) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 18 and 19; Probably localized in the cytoplasmic membrane; Family membership; SusD/RagB family lipoprotein 225111 10974759 zobellia_191 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734656.1 223417 R 63186 CDS YP_004734657.1 340616204 10974770 complement(225122..228244) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (52-125) and the Plug module (141-255) acting as a channel gate; The signal peptide is cleaved between the residues 33 and 34; Family membership; TonB-dependent Receptor 228244 10974770 zobellia_192 Zobellia galactanivorans TonB-dependent Receptor YP_004734657.1 225122 R 63186 CDS YP_004734658.1 340616205 10974778 complement(228605..229540) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 229540 10974778 zobellia_193 Zobellia galactanivorans AraC family transcriptional regulator YP_004734658.1 228605 R 63186 CDS YP_004734659.1 340616206 10974786 229623..230822 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 230822 10974786 zobellia_194 Zobellia galactanivorans lipoprotein YP_004734659.1 229623 D 63186 CDS YP_004734660.1 340616207 10974793 230829..231515 1 NC_015844.1 Regulator of ribonuclease activity is a general modulator of RNA abundance which inhibits the endonuclease activity of the RNase E and thereby leads to increase the half-life of RNAs; Contains a Demethylmenaquinone methyltransferase domain; Localized in the cytoplasm; Conserved hypothetical protein; regulator of ribonuclease activity 231515 rraA1 10974793 rraA1 Zobellia galactanivorans regulator of ribonuclease activity YP_004734660.1 230829 D 63186 CDS YP_004734661.1 340616208 10978551 231679..233847 1 NC_015844.1 Glycoside hydrolases hydrolyse the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non-carbohydrate moiety. This enzyme belongs to the family 31 of the glycoside hydrolases (GH 31); Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Specificity unclear; glycoside hydrolase 233847 10978551 zobellia_196 Zobellia galactanivorans glycoside hydrolase YP_004734661.1 231679 D 63186 CDS YP_004734662.1 340616209 10974810 233887..235503 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide cleaved between the residue 24 and 25; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 235503 fucA10 10974810 fucA10 Zobellia galactanivorans alpha-L-fucosidase YP_004734662.1 233887 D 63186 CDS YP_004734663.1 340616210 10977857 235697..235930 1 NC_015844.1 Hypothetical protein; hypothetical protein 235930 10977857 zobellia_198 Zobellia galactanivorans hypothetical protein YP_004734663.1 235697 D 63186 CDS YP_004734664.1 340616211 10974825 complement(235945..237537) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 20 and 21; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 237537 10974825 zobellia_199 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734664.1 235945 R 63186 CDS YP_004734665.1 340616212 10974833 complement(237537..240674) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules (Here, possibly sugars) that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (58-134) and the Plug module (148-255) acting as a channel gate; The signal peptide is cleaved between the residues 23 and 24; Family membership; TonB-dependent Receptor 240674 10974833 zobellia_200 Zobellia galactanivorans TonB-dependent Receptor YP_004734665.1 237537 R 63186 CDS YP_004734666.1 340616213 10974844 241120..242964 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a N-terminal transmembrane segment followed by two periplasmic tetratrico peptide repeats (TPRs) and a C-terminal cytoplasmic AraC-type HTH domain. The TPR repeats and the AraC-type HTH domain are separated by a second transmembrane segment. TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Localized in the cytoplasmic membrane.; Function unclear; AraC family transcriptional regulator 242964 10974844 zobellia_201 Zobellia galactanivorans AraC family transcriptional regulator YP_004734666.1 241120 D 63186 CDS YP_004734667.1 340616214 10974853 complement(242961..243503) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 243503 10974853 zobellia_202 Zobellia galactanivorans hypothetical protein YP_004734667.1 242961 R 63186 CDS YP_004734668.1 340616215 10974860 243507..243617 1 NC_015844.1 Hypothetical protein; hypothetical protein 243617 10974860 zobellia_203 Zobellia galactanivorans hypothetical protein YP_004734668.1 243507 D 63186 CDS YP_004734669.1 340616216 10974871 complement(243610..243732) 1 NC_015844.1 Hypothetical protein; hypothetical protein 243732 10974871 zobellia_204 Zobellia galactanivorans hypothetical protein YP_004734669.1 243610 R 63186 CDS YP_004734670.1 340616217 10974881 complement(244031..245296) 1 NC_015844.1 Contains a C-terminal domain of unknown function (100 aa) and a lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; hypothetical protein 245296 10974881 zobellia_205 Zobellia galactanivorans hypothetical protein YP_004734670.1 244031 R 63186 CDS YP_004734671.1 340616218 10974889 complement(245329..247131) 1 NC_015844.1 Modular protein consisting of a C-terminal domain of unknown function (DUF814) and a N-terminal domain belonging to the family 1 of sulfatases. The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; Family membership; sulfatase 247131 10974889 zobellia_206 Zobellia galactanivorans sulfatase YP_004734671.1 245329 R 63186 CDS YP_004734672.1 340616219 10974898 247342..248979 1 NC_015844.1 Contains one N-terminal transmembrane segment, then four N-terminal tetratricopeptide repeats (TPR), and a C-terminal LuxR-type HTH domain. The TPRs and the HTH domains are separated by a second transmembrane segment; This Protein could interact with the DNA (transcriptional control or transcription factor); localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 248979 10974898 zobellia_207 Zobellia galactanivorans membrane protein YP_004734672.1 247342 D 63186 CDS YP_004734673.1 340616220 10974902 complement(249036..250229) 1 NC_015844.1 Endoglucanase catalyzes the endohydrolysis of the 1, 4-beta-D-glucosidic linkages in lichenan, cereal beta-D-glucans and carboxymethyl-cellulose and the 1,4-beta-D-xylosidic linkages in xylans. This enzyme is highly; Specificity unclear; endoglucanase 250229 engA 10974902 engA Zobellia galactanivorans endoglucanase YP_004734673.1 249036 R 63186 CDS YP_004734674.1 340616221 10977778 complement(250450..252039) 1 NC_015844.1 Lipoprotein that probably is involved in the sugar metabolism (possibly the polygalactoses or related sugars); Contains a C-terminal carbohydrate binding module of the family 4 (CBM4); Signal peptide cleaved between the residues 26 and 27; Localized in the outer membrane; Hypothetical protein; hypothetical protein 252039 10977778 zobellia_209 Zobellia galactanivorans hypothetical protein YP_004734674.1 250450 R 63186 CDS YP_004734675.1 340616222 10974916 complement(252049..253074) 1 NC_015844.1 Signal peptide cleaved between the residues 17 and 18; Localized in the outer membrane; Hypothetical protein; hypothetical protein 253074 10974916 zobellia_210 Zobellia galactanivorans hypothetical protein YP_004734675.1 252049 R 63186 CDS YP_004734676.1 340616223 10974925 complement(253138..254865) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 254865 10974925 zobellia_211 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734676.1 253138 R 63186 CDS YP_004734677.1 340616224 10974932 complement(254885..257734) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a Plug module (60-151) acting as a channel gate; The signal peptide is cleaved between the residues 26 and 27; Family membership; TonB-dependent Receptor 257734 10974932 zobellia_212 Zobellia galactanivorans TonB-dependent Receptor YP_004734677.1 254885 R 63186 CDS YP_004734678.1 340616225 10974940 complement(257772..259580) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 259580 10974940 zobellia_213 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734678.1 257772 R 63186 CDS YP_004734679.1 340616226 10974950 complement(259592..262690) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (25-99) and the Plug module (115-223) acting as a channel gate; The signal peptide is cleaved between the residues 17 and 18; Family membership; TonB-dependent Receptor 262690 10974950 zobellia_214 Zobellia galactanivorans TonB-dependent Receptor YP_004734679.1 259592 R 63186 CDS YP_004734680.1 340616227 10974957 complement(263361..267488) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 267488 10974957 zobellia_215 Zobellia galactanivorans one-component system sensor protein YP_004734680.1 263361 R 63186 CDS YP_004734681.1 340616228 10974964 268189..268617 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 268617 10974964 zobellia_216 Zobellia galactanivorans hypothetical protein YP_004734681.1 268189 D 63186 CDS YP_004734682.1 340616229 10974972 268674..269603 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; Family membership; ABC transporter ATPase 269603 10974972 zobellia_217 Zobellia galactanivorans ABC transporter ATPase YP_004734682.1 268674 D 63186 CDS YP_004734683.1 340616230 10974976 269606..270328 1 NC_015844.1 ABC-2 Type (ATP-binding cassette) transporter, membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 270328 10974976 zobellia_218 Zobellia galactanivorans ABC transporter permease YP_004734683.1 269606 D 63186 CDS YP_004734684.1 340616231 10974981 270344..271846 1 NC_015844.1 Contains a N-terminal and a C-terminal transmembrane segments and, between both transmembrane helices, a large periplasmic domain; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 271846 10974981 zobellia_219 Zobellia galactanivorans membrane protein YP_004734684.1 270344 D 63186 CDS YP_004734685.1 340616232 10974991 271870..272832 1 NC_015844.1 Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 272832 10974991 zobellia_220 Zobellia galactanivorans hypothetical protein YP_004734685.1 271870 D 63186 CDS YP_004734686.1 340616233 10975000 272903..274051 1 NC_015844.1 Contains a C-terminal transmembrane segments; Signal peptide cleaved between the residues 27 and 28; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 274051 10975000 zobellia_221 Zobellia galactanivorans membrane protein YP_004734686.1 272903 D 63186 CDS YP_004734687.1 340616234 10975009 274051..275013 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; Belongs to the type I secretion system; Family membership; ABC transporter ATPase 275013 10975009 zobellia_222 Zobellia galactanivorans ABC transporter ATPase YP_004734687.1 274051 D 63186 CDS YP_004734688.1 340616235 10975018 275016..276092 1 NC_015844.1 ABC-2 Type (ATP-binding cassette) transporter, membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 276092 10975018 zobellia_223 Zobellia galactanivorans ABC transporter permease YP_004734688.1 275016 D 63186 CDS YP_004734689.1 340616236 10975026 276109..276252 1 NC_015844.1 Hypothetical protein; hypothetical protein 276252 10975026 zobellia_224 Zobellia galactanivorans hypothetical protein YP_004734689.1 276109 D 63186 CDS YP_004734690.1 340616237 10975034 complement(276283..276444) 1 NC_015844.1 Protein fragment found in various hypothetical proteins from many bacteroidetes; hypothetical protein 276444 10975034 zobellia_225 Zobellia galactanivorans hypothetical protein YP_004734690.1 276283 R 63186 CDS YP_004734691.1 340616238 10975039 complement(276509..277369) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 277369 10975039 zobellia_226 Zobellia galactanivorans AraC family transcriptional regulator YP_004734691.1 276509 R 63186 CDS YP_004734692.1 340616239 10975043 277631..280720 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (28-104) and the Plug module (120-230) acting as a channel gate; The signal peptide is cleaved between the residues 25 and 26; Family membership; TonB-dependent Receptor 280720 10975043 zobellia_227 Zobellia galactanivorans TonB-dependent Receptor YP_004734692.1 277631 D 63186 CDS YP_004734693.1 340616240 10975050 280733..282229 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the cytoplasmic membrane; Family membership; SusD/RagB family lipoprotein 282229 10975050 zobellia_228 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734693.1 280733 D 63186 CDS YP_004734694.1 340616241 10975059 282229..283158 1 NC_015844.1 Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Probably localized in the outer membrane; Hypothetical protein; hypothetical protein 283158 10975059 zobellia_229 Zobellia galactanivorans hypothetical protein YP_004734694.1 282229 D 63186 CDS YP_004734695.1 340616242 10975067 283208..284761 1 NC_015844.1 Seems to contain a signal peptide of lipoprotein cleaved between the residues 16 and 17; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 284761 10975067 zobellia_230 Zobellia galactanivorans lipoprotein YP_004734695.1 283208 D 63186 CDS YP_004734696.1 340616243 10975079 284828..285847 1 NC_015844.1 Conserved protein which is predicted as a possible new glycoside hydrolase family; Belongs to the DUF377 family; Localized in the cytoplasm; Family membership; Putative glycoside hydrolase 285847 10975079 zobellia_231 Zobellia galactanivorans Putative glycoside hydrolase YP_004734696.1 284828 D 63186 CDS YP_004734697.1 340616244 10975090 286004..287641 1 NC_015844.1 Sodium/glucose symporter actively transports glucose into cells by Na+ cotransport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains fourteen transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; sodium/glucose symporter 287641 10975090 zobellia_232 Zobellia galactanivorans sodium/glucose symporter YP_004734697.1 286004 D 63186 CDS YP_004734698.1 340616245 10975100 287724..288557 1 NC_015844.1 Acetylxylan esterase catalyzes the deacetylation of xylans and xylo-oligosaccharides. Belongs to the family 6 of the carbohydrate esterases. Features a signal peptide cleaved between residues 20 and 21. Localized in the periplasm.; High confidence in function and specificity; acetylxylan esterase 288557 bnaI 10975100 bnaI Zobellia galactanivorans acetylxylan esterase YP_004734698.1 287724 D 63186 CDS YP_004734699.1 340616246 10977608 complement(288677..289540) 1 NC_015844.1 The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Contains a N-terminal haloalkane dehalogenase domain; Belongs to alpha/beta hydrolase superfamily, dmpD/todF/xylF esterase family; Localized in the cytoplasm; Function unclear; alpha/beta hydrolase-fold protein 289540 10977608 zobellia_234 Zobellia galactanivorans alpha/beta hydrolase-fold protein YP_004734699.1 288677 R 63186 CDS YP_004734700.1 340616247 10975108 complement(289728..290291) 1 NC_015844.1 Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership; TetR family transcriptional regulator 290291 10975108 zobellia_235 Zobellia galactanivorans TetR family transcriptional regulator YP_004734700.1 289728 R 63186 CDS YP_004734701.1 340616248 10975111 290722..292362 1 NC_015844.1 Kappa-carrageenase Hydrolyses the 1,4-beta-D-galactosidic linkages in kappa-carrageenan giving the tetramer as the predominant product; Modular enzyme containing a N-terminal catalytic domain belonging to the family 16 of the glycoside hydrolases, a central Carbohydrate Binding Module of the family CBM16 and a C-terminal domain of unknown function; Signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space and possibly secreted in the outside medium; High confidence in function and specificity; Kappa-carrageenase 292362 cgkA 10975111 cgkA Zobellia galactanivorans Kappa-carrageenase YP_004734701.1 290722 D 63186 CDS YP_004734702.1 340616249 10977648 complement(292495..294228) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 294228 10977648 zobellia_237 Zobellia galactanivorans hypothetical protein YP_004734702.1 292495 R 63186 CDS YP_004734703.1 340616250 10975121 complement(294292..296313) 1 NC_015844.1 Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 296313 10975121 zobellia_238 Zobellia galactanivorans periplasmic protein YP_004734703.1 294292 R 63186 CDS YP_004734704.1 340616251 10975126 complement(296342..297664) 1 NC_015844.1 Protein distantly related to the glycoside hydrolases of the families GH37 and GH63 (clan GH-G); Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; hypothetical protein 297664 10975126 zobellia_239 Zobellia galactanivorans hypothetical protein YP_004734704.1 296342 R 63186 CDS YP_004734705.1 340616252 10975133 complement(297856..299319) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the cytoplasmic membrane; Family membership; SusD/RagB family lipoprotein 299319 10975133 zobellia_240 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734705.1 297856 R 63186 CDS YP_004734706.1 340616253 10975144 complement(299337..302444) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (43-117) and the Plug module (133-240) acting as a channel gate; The signal peptide is cleaved between the residues 25 and 26; Family membership; TonB-dependent Receptor 302444 10975144 zobellia_241 Zobellia galactanivorans TonB-dependent Receptor YP_004734706.1 299337 R 63186 CDS YP_004734707.1 340616254 10975152 complement(302688..306872) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 306872 10975152 zobellia_242 Zobellia galactanivorans one-component system sensor protein YP_004734707.1 302688 R 63186 CDS YP_004734708.1 340616255 10975160 307298..307606 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 307606 10975160 zobellia_243 Zobellia galactanivorans hypothetical protein YP_004734708.1 307298 D 63186 CDS YP_004734709.1 340616256 10975169 complement(307816..309600) 1 NC_015844.1 The large subunit of the ribonucleoside-diphosphate reductase, is a part of a complex which is an heterotetramer of two large and two small subunits. The complex catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Localized in the cytoplasm; High confidence in function and specificity; ribonucleoside-diphosphate reductase, large subunit 309600 rnrA2 10975169 rnrA2 Zobellia galactanivorans ribonucleoside-diphosphate reductase, large subunit YP_004734709.1 307816 R 63186 CDS YP_004734710.1 340616257 10978486 complement(309601..310875) 1 NC_015844.1 The small subunit of the ribonucleoside-diphosphate reductase is a part of a complex which is an heterotetramer of two large and two small subunits. The complex catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Contains a N- terminal evolutionarily mobile, ATP-binding regulatory domain (ATP cone domain) which binds either ATP (activating) or dATP (inhibitory). Substrate binding to the ATP cone domain is thought to alter the relative positions of the two subunits of ribonucleoside- diphosphate reductase; Binds two iron ions by subunit; Localized in the cytoplasm; High confidence in function and specificity; ribonucleoside-diphosphate reductase, small subunit 310875 rnrB2 10978486 rnrB2 Zobellia galactanivorans ribonucleoside-diphosphate reductase, small subunit YP_004734710.1 309601 R 63186 CDS YP_004734711.1 340616258 10978488 complement(311419..311511) 1 NC_015844.1 Hypothetical protein; hypothetical protein 311511 10978488 zobellia_246 Zobellia galactanivorans hypothetical protein YP_004734711.1 311419 R 63186 CDS YP_004734712.1 340616259 10975188 311805..314891 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (55-128) and the Plug module (144-260) acting as a channel gate; The signal peptide is cleaved between the residues 30 and 31; Family membership; TonB-dependent Receptor 314891 10975188 zobellia_247 Zobellia galactanivorans TonB-dependent Receptor YP_004734712.1 311805 D 63186 CDS YP_004734713.1 340616260 10975196 314940..316685 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 21 and 22; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 316685 10975196 zobellia_248 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734713.1 314940 D 63186 CDS YP_004734714.1 340616261 10975201 316803..317873 1 NC_015844.1 Possibly localized in the cytoplasm; hypothetical protein 317873 10975201 zobellia_249 Zobellia galactanivorans hypothetical protein YP_004734714.1 316803 D 63186 CDS YP_004734715.1 340616262 10975210 317879..319690 1 NC_015844.1 The exact specificity of this conserved phosphoesterase is not known; Belongs to the Calcineurin family; Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Specificity unclear; calcineurin-like phosphoesterase 319690 10975210 zobellia_250 Zobellia galactanivorans calcineurin-like phosphoesterase YP_004734715.1 317879 D 63186 CDS YP_004734716.1 340616263 10975220 319737..319883 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 319883 10975220 zobellia_251 Zobellia galactanivorans hypothetical protein YP_004734716.1 319737 D 63186 CDS YP_004734717.1 340616264 10975227 complement(319895..320689) 1 NC_015844.1 Also called 5-keto-D-gluconate 5-reductase; Catalyzes the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate using NADP as a coenzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity; gluconate-5-dehydrogenase 320689 idnO3 10975227 idnO3 Zobellia galactanivorans gluconate-5-dehydrogenase YP_004734717.1 319895 R 63186 CDS YP_004734718.1 340616265 10978022 complement(320793..322973) 1 NC_015844.1 Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains 13 transmembrane helices; Localized in the cytoplasmic membrane; Family membership; sodium/solute symporter 322973 10978022 zobellia_253 Zobellia galactanivorans sodium/solute symporter YP_004734718.1 320793 R 63186 CDS YP_004734719.1 340616266 10975228 323472..325748 1 NC_015844.1 Signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 325748 10975228 zobellia_254 Zobellia galactanivorans hypothetical protein YP_004734719.1 323472 D 63186 CDS YP_004734720.1 340616267 10975229 325889..326722 1 NC_015844.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase is involved in pectin degradation by pectinolytic microorganisms; Localized in the cytoplasm; High confidence in function and specificity; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 326722 kduI2 10975229 kduI2 Zobellia galactanivorans 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase YP_004734720.1 325889 D 63186 CDS YP_004734721.1 340616268 10978063 326738..327940 1 NC_015844.1 This protein belongs to the family 105 of the glycoside hydrolases. These enzymes are involved in the catabolism of unsaturated oligosaccharides produced by polysaccharide lyases. Asp183 is the putative catalytic residue (identical to Asp143 of the unsaturated rhamnogalacturonyl hydrolase from Bacillus subtilis, Itoh et al., 2006, BBRC 347, 10211029).; Specificity unclear; glycoside hydrolase 327940 10978063 zobellia_256 Zobellia galactanivorans glycoside hydrolase YP_004734721.1 326738 D 63186 CDS YP_004734722.1 340616269 10975248 complement(328095..330323) 1 NC_015844.1 Large conserved protein containing a C-terminal cytochrome c. Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes. Contains a putative lipoprotein signal peptide cleaved between the residues 22 and 23; Possibly localized in the outer membrane; Conserved hypothetical protein; cytochrome c-containing protein 330323 10975248 zobellia_257 Zobellia galactanivorans cytochrome c-containing protein YP_004734722.1 328095 R 63186 CDS YP_004734723.1 340616270 10975256 complement(330425..331930) 1 NC_015844.1 Contains a N-terminal domain of unknown function and a C-terminal domain displaying three Kelch repeats. The kelch motif forms a beta sheet and several of these sheets associate to form a beta propeller structure; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Family membership; Kelch repeat-containing protein 331930 10975256 zobellia_258 Zobellia galactanivorans Kelch repeat-containing protein YP_004734723.1 330425 R 63186 CDS YP_004734724.1 340616271 10975266 complement(331917..336980) 1 NC_015844.1 Hypothetical protein featuring a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 336980 10975266 zobellia_259 Zobellia galactanivorans hypothetical protein YP_004734724.1 331917 R 63186 CDS YP_004734725.1 340616272 10975277 complement(337016..339022) 1 NC_015844.1 Hypothetical protein featuring a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 339022 10975277 zobellia_260 Zobellia galactanivorans hypothetical protein YP_004734725.1 337016 R 63186 CDS YP_004734726.1 340616273 10975285 complement(339153..341732) 1 NC_015844.1 Hypothetical protein containing an uncleaved signal peptide. Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 341732 10975285 zobellia_261 Zobellia galactanivorans hypothetical protein YP_004734726.1 339153 R 63186 CDS YP_004734727.1 340616274 10975295 complement(341775..341924) 1 NC_015844.1 Hypothetical protein; hypothetical protein 341924 10975295 zobellia_262 Zobellia galactanivorans hypothetical protein YP_004734727.1 341775 R 63186 CDS YP_004734728.1 340616275 10975303 complement(341985..344318) 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 95 of the glycoside hydrolases (GH95); Features a lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the cytoplasmic or/and outer membrane; High confidence in function and specificity; alpha-L-fucosidase 344318 afcA1 10975303 afcA1 Zobellia galactanivorans alpha-L-fucosidase YP_004734728.1 341985 R 63186 CDS YP_004734729.1 340616276 10977476 344405..344539 1 NC_015844.1 Hypothetical protein; hypothetical protein 344539 10977476 zobellia_264 Zobellia galactanivorans hypothetical protein YP_004734729.1 344405 D 63186 CDS YP_004734730.1 340616277 10975320 344523..344627 1 NC_015844.1 Hypothetical protein; hypothetical protein 344627 10975320 zobellia_265 Zobellia galactanivorans hypothetical protein YP_004734730.1 344523 D 63186 CDS YP_004734731.1 340616278 10975331 complement(344850..346526) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 20 and 21; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 346526 10975331 zobellia_266 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734731.1 344850 R 63186 CDS YP_004734732.1 340616279 10975341 complement(346544..349666) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations. Contains a carboxypeptidase regulatory domain (31-104) and the Plug module (120-218) acting as a channel gate. The signal peptide is cleaved between the residues 29 and 30.; Family membership; TonB-dependent Receptor 349666 10975341 zobellia_267 Zobellia galactanivorans TonB-dependent Receptor YP_004734732.1 346544 R 63186 CDS YP_004734733.1 340616280 10975351 349767..349910 1 NC_015844.1 Hypothetical protein; hypothetical protein 349910 10975351 zobellia_268 Zobellia galactanivorans hypothetical protein YP_004734733.1 349767 D 63186 CDS YP_004734734.1 340616281 10975362 350262..354335 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains two transmembrane segments; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 354335 10975362 zobellia_269 Zobellia galactanivorans one-component system sensor protein YP_004734734.1 350262 D 63186 CDS YP_004734735.1 340616282 10975373 complement(354389..354964) 1 NC_015844.1 Peroxiredoxin is a thioredoxin-dependent thiol peroxidase. BCP preferentially reduced linoleic acid hydroperoxide rather than H2O2 and t-butyl hydroperoxide with the use of thioredoxin as an in vivo immediate electron donor. Localized in the cytoplasm.; High confidence in function and specificity; peroxiredoxin 354964 bcpA 10975373 bcpA Zobellia galactanivorans peroxiredoxin YP_004734735.1 354389 R 63186 CDS YP_004734736.1 340616283 10977590 355533..358625 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (30-103) and the Plug module (119-242) acting as a channel gate; The signal peptide is cleaved between the residues 28 and 29; Family membership; TonB-dependent Receptor 358625 10977590 zobellia_271 Zobellia galactanivorans TonB-dependent Receptor YP_004734736.1 355533 D 63186 CDS YP_004734737.1 340616284 10975388 358648..360237 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Would contain a lipoprotein signal peptide cleaved between the residues 24 and 25; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 360237 10975388 zobellia_272 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734737.1 358648 D 63186 CDS YP_004734738.1 340616285 10975399 360425..363988 1 NC_015844.1 ASPIC and UnbV sequences are found associated with tetratrico peptide repeat in several paralogous proteins in Rhodopirellula baltica and with FG-GAP repeats in several eukaryotic integrin-like proteins and in several other bacterial proteins. The FG-GAP repeat has been predicted to fold into a beta propeller structure. The FG- GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding; Contains a signal peptide of lipoprotein cleaved between the residues 21 and 22; Protein putatively localized in the cytoplasmic membrane; Function unclear; ASPIC/UnbV-like protein 363988 10975399 zobellia_273 Zobellia galactanivorans ASPIC/UnbV-like protein YP_004734738.1 360425 D 63186 CDS YP_004734739.1 340616286 10975407 364203..365114 1 NC_015844.1 Conserved phosphatase belonging to the Ppx/GppA family, which includes exopolyphosphate phosphatase (Ppx) and guanosine pentaphosphate phosphatase (GppA). Its exact specificity is unclear; Localized in the cytoplasm; Specificity unclear; Ppx/GppA-like phosphatase 365114 10975407 zobellia_274 Zobellia galactanivorans Ppx/GppA-like phosphatase YP_004734739.1 364203 D 63186 CDS YP_004734740.1 340616287 10975417 365336..365440 1 NC_015844.1 Hypothetical protein; hypothetical protein 365440 10975417 zobellia_275 Zobellia galactanivorans hypothetical protein YP_004734740.1 365336 D 63186 CDS YP_004734741.1 340616288 10975424 365444..365752 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 365752 10975424 zobellia_276 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004734741.1 365444 D 63186 CDS YP_004734742.1 340616289 10975433 365829..367109 1 NC_015844.1 Conserved protein belonging to the xylose isomerase family. Its exact specificity is unclear. Localized in the cytoplasm.; Specificity unclear; sugar isomerase 367109 10975433 zobellia_277 Zobellia galactanivorans sugar isomerase YP_004734742.1 365829 D 63186 CDS YP_004734743.1 340616290 10975439 367431..368843 1 NC_015844.1 Contains eleven transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 368843 10975439 zobellia_278 Zobellia galactanivorans membrane protein YP_004734743.1 367431 D 63186 CDS YP_004734744.1 340616291 10975447 369097..369837 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 369837 10975447 zobellia_279 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004734744.1 369097 D 63186 CDS YP_004734745.1 340616292 10975453 370016..370942 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons. Contains two C-terminal AraC-type HTH DNA-binding domains involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization. Localized in the cytoplasm.; Specificity unclear; AraC family transcriptional regulator 370942 10975453 zobellia_280 Zobellia galactanivorans AraC family transcriptional regulator YP_004734745.1 370016 D 63186 CDS YP_004734746.1 340616293 10975459 371305..371970 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 371970 10975459 zobellia_281 Zobellia galactanivorans lipoprotein YP_004734746.1 371305 D 63186 CDS YP_004734747.1 340616294 10975469 complement(372015..372404) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 372404 10975469 zobellia_282 Zobellia galactanivorans hypothetical protein YP_004734747.1 372015 R 63186 CDS YP_004734748.1 340616295 10975476 complement(373155..373676) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 373676 10975476 zobellia_283 Zobellia galactanivorans hypothetical protein YP_004734748.1 373155 R 63186 CDS YP_004734749.1 340616296 10975485 374197..374724 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 374724 10975485 zobellia_284 Zobellia galactanivorans hypothetical protein YP_004734749.1 374197 D 63186 CDS YP_004734750.1 340616297 10975491 complement(375233..375895) 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Hypothetical protein; hypothetical protein 375895 10975491 zobellia_285 Zobellia galactanivorans hypothetical protein YP_004734750.1 375233 R 63186 CDS YP_004734751.1 340616298 10975498 complement(375899..376408) 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 376408 10975498 zobellia_286 Zobellia galactanivorans hypothetical protein YP_004734751.1 375899 R 63186 CDS YP_004734752.1 340616299 10975505 377152..378963 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 378963 10975505 zobellia_287 Zobellia galactanivorans hypothetical protein YP_004734752.1 377152 D 63186 CDS YP_004734753.1 340616300 10975512 complement(379110..379340) 1 NC_015844.1 Hypothetical protein; hypothetical protein 379340 10975512 zobellia_288 Zobellia galactanivorans hypothetical protein YP_004734753.1 379110 R 63186 CDS YP_004734754.1 340616301 10975520 379419..379751 1 NC_015844.1 Contains three transmembrane helices. Localized in the cytoplasmic membrane.; Hypothetical protein; hypothetical protein 379751 10975520 zobellia_289 Zobellia galactanivorans hypothetical protein YP_004734754.1 379419 D 63186 CDS YP_004734755.1 340616302 10975531 complement(379907..381655) 1 NC_015844.1 This protein displays is distantly related to Papain family cysteine peptidases. It also features a conserved motif GAHSVLLVGFD (G246-D256) which is usually typical for the catalytic site of cysteine peptidases (Prosite: PS00639). These enzymes contain an active site cysteine. Catalysis proceeds through a thioester intermediate and is facilitated by a nearby histidine side chain; an asparagine completes the essential catalytic triad. This protein is localized in the cytoplasm.; Hypothetical protein; Putative cysteine peptidase 381655 10975531 zobellia_290 Zobellia galactanivorans Putative cysteine peptidase YP_004734755.1 379907 R 63186 CDS YP_004734756.1 340616303 10975540 382261..382722 1 NC_015844.1 Transcriptional regulator belonging to the Xre family. Features a helix-turn-helix DNA binding motif. Localized in the cytoplasm.; Specificity unclear; XRE family transcriptional regulator 382722 10975540 zobellia_291 Zobellia galactanivorans XRE family transcriptional regulator YP_004734756.1 382261 D 63186 CDS YP_004734757.1 340616304 10975547 382713..383309 1 NC_015844.1 This protein belongs to a family including the Fic protein (filamentation induced by cAMP). The Fic protein is involved in cell division and is suggested to be involved in the synthesis of PAB or folate, indicating that the Fic protein and cAMP are involved in a regulatory mechanism of cell division via folate metabolism. This family contains a central conserved motif HPFXXGNG in most members. The exact molecular function of these proteins is uncertain. Localized in the cytoplasm.; Family membership; Fic family protein 383309 10975547 zobellia_292 Zobellia galactanivorans Fic family protein YP_004734757.1 382713 D 63186 CDS YP_004734758.1 340616305 10975556 complement(383481..384113) 1 NC_015844.1 This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. It displays a N-terminal cyclic nucleotide-binding domain and a C-terminal helix-turn-helix DNA-binding domain. The cyclic nucleotide-binding domain is composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure. There are six invariant amino acids in this domain, three of which are glycine residues that are thought to be essential for maintenance of the structural integrity of the beta- barrel. Localized in the cytoplasm.; Specificity unclear; catabolite gene activator 384113 crpA1 10975556 crpA1 Zobellia galactanivorans catabolite gene activator YP_004734758.1 383481 R 63186 CDS YP_004734759.1 340616306 10977675 complement(384191..384400) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 384400 10977675 zobellia_294 Zobellia galactanivorans membrane protein YP_004734759.1 384191 R 63186 CDS YP_004734760.1 340616307 10975568 complement(384488..384760) 1 NC_015844.1 This protein belongs to the Heavy metal transport protein family. The Heavy-Metal-Associated (HMA) domain contains two conserved cysteines that are probably involved in metal binding. Its structure comprises our- stranded antiparallel beta-sheet and two alpha helices packed in an alpha-beta sandwich fold. Somes of these HMA proteins are involved in bacterial resistance to toxic metals, such as lead and cadmium. Localized in the cytoplasm.; Specificity unclear; heavy metal binding protein 384760 10975568 zobellia_295 Zobellia galactanivorans heavy metal binding protein YP_004734760.1 384488 R 63186 CDS YP_004734761.1 340616308 10975578 complement(384814..385158) 1 NC_015844.1 Thiosulfate sulfurtransferase catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide; The relatively low affinity of GlpE for both thiosulfate and cyanide suggests that these compounds are not the physiological substrates. Thioredoxin 1 or related dithiol proteins could instead be the physiological sulfur-acceptor substrate; Contains one only rhodanese domain; Localized in the cytoplasm; High confidence in function and specificity; thiosulfate sulfurtransferase 385158 glpE2 10975578 glpE2 Zobellia galactanivorans thiosulfate sulfurtransferase YP_004734761.1 384814 R 63186 CDS YP_004734762.1 340616309 10977922 complement(385320..386735) 1 NC_015844.1 Conserved protein with a N-terminal domain belonging to the metallo-beta-lactamase superfamily and two rhodanese (thiosulfate sulfurtransferase) domains: one where the active-site cysteine residue is replaced by another aminoacid whereas the C-terminal domain displays the catalytic cysteine residue. contains various metallo-hydrolases including beta-lactamases, but also glyoxylases and arylsulfatases. The active site is characterized by several conserved histidines binding the catalytic zinc ions. The enzymes can bind one or two zinc ions; Localized in the cytoplasm; Function unclear; metallo-beta-lactamase superfamily protein 386735 10977922 zobellia_297 Zobellia galactanivorans metallo-beta-lactamase superfamily protein YP_004734762.1 385320 R 63186 CDS YP_004734763.1 340616310 10975591 complement(386991..387536) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the cytoplasmic membrane and/or outer membrane; Hypothetical protein; hypothetical protein 387536 10975591 zobellia_298 Zobellia galactanivorans hypothetical protein YP_004734763.1 386991 R 63186 CDS YP_004734764.1 340616311 10975598 387671..387802 1 NC_015844.1 Hypothetical protein; hypothetical protein 387802 10975598 zobellia_299 Zobellia galactanivorans hypothetical protein YP_004734764.1 387671 D 63186 CDS YP_004734765.1 340616312 10975609 complement(387799..388713) 1 NC_015844.1 Tryptophan 2,3-dioxygenase is Involved in L-kynurenine metabolism from L-tryptophan,incorporating oxygen into the indole moiety of tryptophan. It has a broad specificity towards tryptamine and derivatives including D-and L-tryptophan, 5-hydroxytryptophan and serotonin; This enzyme forms a tetramer and binds 2 hemes per subunit; Localized in the cytoplasm; High confidence in function and specificity; tryptophan 2,3-dioxygenase 388713 tdoA1 10975609 tdoA1 Zobellia galactanivorans tryptophan 2,3-dioxygenase YP_004734765.1 387799 R 63186 CDS YP_004734766.1 340616313 10978644 complement(388717..389154) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 389154 10978644 zobellia_301 Zobellia galactanivorans membrane protein YP_004734766.1 388717 R 63186 CDS YP_004734767.1 340616314 10975630 complement(389151..389540) 1 NC_015844.1 Truncated hemoglobin; Localized in the cytoplasm; Family membership; globin-like protein 389540 10975630 zobellia_302 Zobellia galactanivorans globin-like protein YP_004734767.1 389151 R 63186 CDS YP_004734768.1 340616315 10975633 complement(389628..390170) 1 NC_015844.1 The transcriptional regulators with the Rrf2-type HTH domain control a variety of operons that encode iron-sulfur-containing proteins as well as other proteins involved in electron transport. Other rrf2-type HTH proteins are repressors of genes involved in nitrite or iron metabolism. The C-terminal part of the rrf2-type HTH domain contains 3 conserved cysteine residues that may bind an Fe-S cluster. Contains a DNA-binding, winged helix-turn-helix (wHTH) domain. Localized in the cytoplasm.; Family membership; Rrf2-type transcriptional regulator 390170 10975633 zobellia_303 Zobellia galactanivorans Rrf2-type transcriptional regulator YP_004734768.1 389628 R 63186 CDS YP_004734769.1 340616316 10975641 complement(390182..391882) 1 NC_015844.1 Sulfite reductase catalyses the six-electron reduction reactions of sulfite to sulfide; This is one of several activities required for the biosynthesis of L-cysteine from sulfate; The enzyme is a complex composed of two subunits, a flavoprotein alpha-component (SiR-FP) and a hemoprotein beta-component (SiR-HP). The quaternary strucure is alpha(8)-beta(4). SiR-HP contains a Fe(4)S(4) cluster coupled to a siroheme through a cysteine bridge; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family; Localized in the cytoplasm; High confidence in function and specificity; sulfite reductase [NADPH] hemoprotein beta-component 391882 cysI 10975641 cysI Zobellia galactanivorans sulfite reductase [NADPH] hemoprotein beta-component YP_004734769.1 390182 R 63186 CDS YP_004734770.1 340616317 10977703 complement(391924..393744) 1 NC_015844.1 Sulfite reductase catalyses the six-electron reduction reactions of sulfite to sulfide; This is one of several activities required for the biosynthesis of L-cysteine from sulfate; The enzyme is a complex composed of two subunits, a flavoprotein alpha-component (SiR-FP) and a hemoprotein beta-component (SiR-HP). The quaternary strucure is alpha(8)-beta(4); The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Binds one FAD and ond FMN per subunit; Localized in the cytoplasm; High confidence in function and specificity; sulfite reductase [NADPH] flavoprotein alpha-component 393744 cysJ 10977703 cysJ Zobellia galactanivorans sulfite reductase [NADPH] flavoprotein alpha-component YP_004734770.1 391924 R 63186 CDS YP_004734771.1 340616318 10977704 complement(393764..394399) 1 NC_015844.1 Peroxiredoxins are thiol peroxidase. They are involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. The peroxidase reaction comprises two steps centered around a redox- active cysteine called the peroxidatic cysteine. It attacks the peroxide substrate and is oxidized to S-hydroxycysteine (a sulfenic acid). The second step is the regeneration of cysteine from S-hydroxycysteine. This regeneration is due to thiol-containing reductants such as thioredoxin. Localized in the cytoplasm.; Specificity unclear; peroxiredoxin 394399 10977704 zobellia_306 Zobellia galactanivorans peroxiredoxin YP_004734771.1 393764 R 63186 CDS YP_004734772.1 340616319 10975661 complement(394632..395525) 1 NC_015844.1 Transcriptional regulator belonging to the LysR family. Features a N-terminal helix-turn-helix DNA binding domain and a C-terminal LysR-like substrate binding domain. Localized in the cytoplasm.; Specificity unclear; LysR family transcriptional regulator 395525 10975661 zobellia_307 Zobellia galactanivorans LysR family transcriptional regulator YP_004734772.1 394632 R 63186 CDS YP_004734773.1 340616320 10975672 396109..396843 1 NC_015844.1 Involved in peptidoglycan cross-linking. Required for normal cell growth and development. Contains two Hemerythrin HHE cation binding domains.; Family membership; cell wall-like protein ScdA 396843 scdA 10975672 scdA Zobellia galactanivorans cell wall-like protein ScdA YP_004734773.1 396109 D 63186 CDS YP_004734774.1 340616321 10978564 396833..397393 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 397393 10978564 zobellia_309 Zobellia galactanivorans hypothetical protein YP_004734774.1 396833 D 63186 CDS YP_004734775.1 340616322 10975693 397491..398009 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 398009 10975693 zobellia_310 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004734775.1 397491 D 63186 CDS YP_004734776.1 340616323 10975701 complement(398070..399887) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasm; Hypothetical protein; hypothetical protein 399887 10975701 zobellia_311 Zobellia galactanivorans hypothetical protein YP_004734776.1 398070 R 63186 CDS YP_004734777.1 340616324 10975709 complement(399989..401641) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Hypothetical protein; SusD/RagB family lipoprotein 401641 10975709 zobellia_312 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734777.1 399989 R 63186 CDS YP_004734778.1 340616325 10975719 complement(401653..404790) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (85-159), and a Plug module (175-281) acting as the channel gate; The signal peptide is cleaved between the residue 32 and 33; Family membership; TonB-dependent transducer 404790 10975719 zobellia_313 Zobellia galactanivorans TonB-dependent transducer YP_004734778.1 401653 R 63186 CDS YP_004734779.1 340616326 10975729 complement(405203..407101) 1 NC_015844.1 Alpha-glucosidases catalyse the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose. Involved in carbohydrate metabolism, notably in starch degradation; Belongs to the family 97 of glycoside hydrolases (GH97); Lipoprotein signal peptide cleaved between the residues 20 and 21; localized in the outer membrane; High confidence in function and specificity; alpha-glucosidase 407101 10975729 zobellia_314 Zobellia galactanivorans alpha-glucosidase YP_004734779.1 405203 R 63186 CDS YP_004734780.1 340616327 10975737 complement(407167..407721) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 407721 10975737 zobellia_315 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004734780.1 407167 R 63186 CDS YP_004734781.1 340616328 10975747 complement(407766..409649) 1 NC_015844.1 Alpha-glucosidases catalyse the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose. Involved in carbohydrate metabolism, notably in starch degradation; Belongs to the family 97 of glycoside hydrolases (GH97); Lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the cytoplasmic or outer membrane or both; High confidence in function and specificity; alpha-glucosidase 409649 10975747 zobellia_316 Zobellia galactanivorans alpha-glucosidase YP_004734781.1 407766 R 63186 CDS YP_004734782.1 340616329 10975752 complement(409698..410486) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 410486 10975752 zobellia_317 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004734782.1 409698 R 63186 CDS YP_004734783.1 340616330 10975762 complement(410499..411386) 1 NC_015844.1 Gluconolactonase or Aldonolactonase hydrolyzes the glyconolactones formed by oxidoreductases acting on various aldohexosaccharides. It hydrolyzes the D-glucono-1,5-lactone to gluconic acid and can act on a wide range of hexono-1,5-lactones; Localized in the cytoplasm; High confidence in function and specificity; gluconolactonase 411386 10975762 zobellia_318 Zobellia galactanivorans gluconolactonase YP_004734783.1 410499 R 63186 CDS YP_004734784.1 340616331 10975770 complement(411405..412565) 1 NC_015844.1 Galactonate dehydratase converts the D-galactonate to 2-dehydro-3-deoxy-D-galactonate; Contains a N-terminal domain with a Enolase N-terminal domain-like fold and a C-terminal TIM alpha/beta barrel fold; Belongs to the Mandelate racemase/muconate lactonizing enzyme family; Localized in the cytoplasm; High confidence in function and specificity; galactonate dehydratase 412565 10975770 zobellia_319 Zobellia galactanivorans galactonate dehydratase YP_004734784.1 411405 R 63186 CDS YP_004734785.1 340616332 10975777 complement(412611..413306) 1 NC_015844.1 Regulator of ribonuclease activity is a general modulator of RNA abundance which inhibits the endonuclease activity of the RNase E and thereby leads to increase the half-life of RNAs; Contains a Demethylmenaquinone methyltransferase domain; Localized in the cytoplasm; Conserved hypothetical protein; dimethylmenaquinone methyltransferase 413306 rraA2 10975777 rraA2 Zobellia galactanivorans dimethylmenaquinone methyltransferase YP_004734785.1 412611 R 63186 CDS YP_004734786.1 340616333 10978552 413447..414322 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 414322 10978552 zobellia_321 Zobellia galactanivorans AraC family transcriptional regulator YP_004734786.1 413447 D 63186 CDS YP_004734787.1 340616334 10975798 complement(414390..415325) 1 NC_015844.1 Aldose 1-epimerase or Mutarotase is responsible for the anomeric interconversion of aldoses between their alpha- and beta-forms; It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; localized in the cytoplasm; High confidence in function and specificity; aldose 1-epimerase 415325 mroA1 10975798 mroA1 Zobellia galactanivorans aldose 1-epimerase YP_004734787.1 414390 R 63186 CDS YP_004734788.1 340616335 10978183 complement(415482..416870) 1 NC_015844.1 The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; major facilitator family transporter 416870 10978183 zobellia_323 Zobellia galactanivorans major facilitator family transporter YP_004734788.1 415482 R 63186 CDS YP_004734789.1 340616336 10975812 complement(416898..417581) 1 NC_015844.1 Conserved protein belonging to the creatine amidohydrolase family; Localized in the cytoplasm; Family membership; creatinase family protein 417581 10975812 zobellia_324 Zobellia galactanivorans creatinase family protein YP_004734789.1 416898 R 63186 CDS YP_004734790.1 340616337 10975823 complement(417820..418806) 1 NC_015844.1 Enzymes that catalyzes the phosphorylation of sugars from ATP; Contains a transmembrane segment in the middle part of protein; Belongs to the ROK family; Seems localized in the cytoplasmic membrane; Family membership; sugar kinase 418806 10975823 zobellia_325 Zobellia galactanivorans sugar kinase YP_004734790.1 417820 R 63186 CDS YP_004734791.1 340616338 10975834 complement(418818..420152) 1 NC_015844.1 Flavoprotein that contains a N-terminal FAD binding domain; Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Possible lipoprotein with a signal peptide cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Function unclear; FAD dependent oxidoreductase 420152 10975834 zobellia_326 Zobellia galactanivorans FAD dependent oxidoreductase YP_004734791.1 418818 R 63186 CDS YP_004734792.1 340616339 10975843 complement(420175..420969) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 420969 10975843 zobellia_327 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004734792.1 420175 R 63186 CDS YP_004734793.1 340616340 10975854 complement(421026..421832) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 421832 10975854 zobellia_328 Zobellia galactanivorans hypothetical protein YP_004734793.1 421026 R 63186 CDS YP_004734794.1 340616341 10975864 complement(421840..422592) 1 NC_015844.1 Transcriptional regulator involved in the repression and/or the positive regulation of genes encoding for enzymes; Contains an N-terminal HTH domain of GntR-like bacterial transcriptional regulators, involved in the binding of the protein to the operator sequences in the DNA and a C-terminal UTRA domain that modulates activity of transcription regulator in response to binding small molecules; Localized in the cytoplasm; Family membership; GntR family transcriptional regulator 422592 10975864 zobellia_329 Zobellia galactanivorans GntR family transcriptional regulator YP_004734794.1 421840 R 63186 CDS YP_004734795.1 340616342 10975875 complement(422589..422690) 1 NC_015844.1 Hypothetical protein; hypothetical protein 422690 10975875 zobellia_330 Zobellia galactanivorans hypothetical protein YP_004734795.1 422589 R 63186 CDS YP_004734796.1 340616343 10975886 complement(422690..423346) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 423346 10975886 zobellia_331 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004734796.1 422690 R 63186 CDS YP_004734797.1 340616344 10975897 complement(423644..425263) 1 NC_015844.1 Mucin-desulfating sulfatases hydrolyse the sulfate groups from oligosaccharides present in mucins (heavily glycosylated proteins). In the mucins, the main sulfated sugars are N-acetyl-D-glucosamine-6-sulfate, galactose-6-sulfate and galactose-3-sulfate; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 11; Signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; Specificity unclear; mucin-desulfating sulfatase 425263 mdsA1 10975897 mdsA1 Zobellia galactanivorans mucin-desulfating sulfatase YP_004734797.1 423644 R 63186 CDS YP_004734798.1 340616345 10978132 complement(425282..427549) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Hypothetical protein; hypothetical protein 427549 10978132 zobellia_333 Zobellia galactanivorans hypothetical protein YP_004734798.1 425282 R 63186 CDS YP_004734799.1 340616346 10975915 complement(427645..429750) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 429750 10975915 zobellia_334 Zobellia galactanivorans hypothetical protein YP_004734799.1 427645 R 63186 CDS YP_004734800.1 340616347 10975926 complement(429957..432275) 1 NC_015844.1 This conserved protein likely adopts a right handed parallel beta-helix fold. Features an uncleaved signal peptide. Localized in the cytoplasmic membrane.; Conserved hypothetical protein; beta-helix fold protein 432275 10975926 zobellia_335 Zobellia galactanivorans beta-helix fold protein YP_004734800.1 429957 R 63186 CDS YP_004734801.1 340616348 10975936 complement(432298..433767) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Putative lipoprotein with a signal peptide cleaved between the residues 18 and 19. Possibly localized in the outer membrane; Family membership; sulfatase 433767 10975936 zobellia_336 Zobellia galactanivorans sulfatase YP_004734801.1 432298 R 63186 CDS YP_004734802.1 340616349 10975944 complement(433779..436157) 1 NC_015844.1 Modular protein containing a N-terminal domain adopting a parallel beta-helix fold and a C-terminal carbohydrate binding module of the family 16 (CBM16). The N-terminal domain is distantly related to the polysaccharide lyases of the family 9 (PL9). Features a signal peptide cleaved between residues 29 and 30. Localized in the periplasm.; Specificity unclear; beta-helix fold protein containing CBM16 436157 10975944 zobellia_337 Zobellia galactanivorans beta-helix fold protein containing CBM16 YP_004734802.1 433779 R 63186 CDS YP_004734803.1 340616350 10975954 complement(436290..437732) 1 NC_015844.1 Modular protein that consists of an N-terminal alpha-L-fucosidase module belonging to the family 29 of glycoside hydrolases (GH29), responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside and a C-terminal domain that could be involved in the binding to specific ligands such as carbohydrate or lipids substrates; Signal peptide cleaved between the residue 18 and 19; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 437732 alfA3 10975954 alfA3 Zobellia galactanivorans alpha-L-fucosidase YP_004734803.1 436290 R 63186 CDS YP_004734804.1 340616351 10977496 complement(437735..439222) 1 NC_015844.1 Modular protein that consists of an N-terminal alpha-L-fucosidase module belonging to the family 29 of glycoside hydrolases (GH29), responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside and a C-terminal domain of two hundred residues that could be involved in the binding to specific ligands such as carbohydrate or lipids substrates; Signal peptide cleaved between the residue 19 and 20; Localized in the outer membrane; High confidence in function and specificity; alpha-L-fucosidase 439222 alfaA2 10977496 alfaA2 Zobellia galactanivorans alpha-L-fucosidase YP_004734804.1 437735 R 63186 CDS YP_004734805.1 340616352 10977500 complement(439278..441716) 1 NC_015844.1 This conserved protein likely adopts a right handed parallel beta-helix fold. Features a signal peptide cleaved between the residues 32 and 33. Localized in the periplasm.; Conserved hypothetical protein; beta-helix fold protein 441716 10977500 zobellia_340 Zobellia galactanivorans beta-helix fold protein YP_004734805.1 439278 R 63186 CDS YP_004734806.1 340616353 10975984 complement(441724..442842) 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide cleaved between the residue 24 and 25; Localized in the outer membrane; High confidence in function and specificity; alpha-L-fucosidase 442842 fucA2 10975984 fucA2 Zobellia galactanivorans alpha-L-fucosidase YP_004734806.1 441724 R 63186 CDS YP_004734807.1 340616354 10977859 complement(442842..444326) 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide cleaved between the residue 25 and 26; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 444326 fucA1 10977859 fucA1 Zobellia galactanivorans alpha-L-fucosidase YP_004734807.1 442842 R 63186 CDS YP_004734808.1 340616355 10977856 complement(444330..446705) 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 95 of the glycoside hydrolases (GH95); Features a lipoprotein signal peptide cleaved between the residues 23 and 24; Localized in the outer membrane; High confidence in function and specificity; alpha-L-fucosidase 446705 afcA2 10977856 afcA2 Zobellia galactanivorans alpha-L-fucosidase YP_004734808.1 444330 R 63186 CDS YP_004734809.1 340616356 10977477 complement(446715..448931) 1 NC_015844.1 XarB catalyzes the hydrolysis of terminal, non-reducing beta-D-xylose residues (or L-arabinose residues ) with release of beta-D-xylose (or alpha-L-arabinose). This bifunctional enzyme belongs to the family 3 of the glycoside hydrolases (GH3); Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasm.; High confidence in function and specificity; xylosidase/arabinosidase 448931 xarB1 10977477 xarB1 Zobellia galactanivorans xylosidase/arabinosidase YP_004734809.1 446715 R 63186 CDS YP_004734810.1 340616357 10978758 complement(448955..450451) 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Localized in the cytoplasm; High confidence in function and specificity; alpha-L-fucosidase 450451 fucA3 10978758 fucA3 Zobellia galactanivorans alpha-L-fucosidase YP_004734810.1 448955 R 63186 CDS YP_004734811.1 340616358 10977860 complement(450465..452453) 1 NC_015844.1 Modular protein that consists of an N-terminal alpha-L-fucosidase module belonging to the family 29 of glycoside hydrolases (GH29), responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside and a C-terminal domain that could be involved in the binding to specific ligands such as carbohydrate or lipids substrates; Signal peptide cleaved between the residue 22 and 23; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 452453 alfA1 10977860 alfA1 Zobellia galactanivorans alpha-L-fucosidase YP_004734811.1 450465 R 63186 CDS YP_004734812.1 340616359 10977495 complement(452462..454867) 1 NC_015844.1 XarB catalyzes the hydrolysis of terminal, non-reducing beta-D-xylose residues (or L-arabinose residues ) with release of beta-D-xylose (or alpha-L-arabinose). This bifunctional enzyme belongs to the family 3 of the glycoside hydrolases. Features an uncleaved signal peptide. Localized in the cytoplasmic membrane.; High confidence in function and specificity; xylosidase/arabinosidase 454867 xarB2 10977495 xarB2 Zobellia galactanivorans xylosidase/arabinosidase YP_004734812.1 452462 R 63186 CDS YP_004734813.1 340616360 10978759 455478..459566 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 459566 10978759 zobellia_348 Zobellia galactanivorans one-component system sensor protein YP_004734813.1 455478 D 63186 CDS YP_004734814.1 340616361 10976057 complement(459907..460818) 1 NC_015844.1 Contains a lipoprotein signal peptide claeved between the residues 17 and 18; Putatively localized in the outer membrane; Hypothetical protein; hypothetical protein 460818 10976057 zobellia_349 Zobellia galactanivorans hypothetical protein YP_004734814.1 459907 R 63186 CDS YP_004734815.1 340616362 10976065 complement(460847..462541) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 17 and 18; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 462541 10976065 zobellia_350 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734815.1 460847 R 63186 CDS YP_004734816.1 340616363 10976075 complement(462558..465536) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (31-94) and the Plug module (123-217) acting as a channel gate; The signal peptide is cleaved between the residues 24 and 25; Family membership; TonB-dependent Receptor 465536 10976075 zobellia_351 Zobellia galactanivorans TonB-dependent Receptor YP_004734816.1 462558 R 63186 CDS YP_004734817.1 340616364 10976085 complement(465562..467346) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 18 and 19; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 467346 10976085 zobellia_352 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734817.1 465562 R 63186 CDS YP_004734818.1 340616365 10976096 complement(467356..470490) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (24-97) and the Plug module (113-222) acting as a channel gate; The signal peptide is cleaved between the residues 21 and 22; Family membership; TonB-dependent Receptor 470490 10976096 zobellia_353 Zobellia galactanivorans TonB-dependent Receptor YP_004734818.1 467356 R 63186 CDS YP_004734819.1 340616366 10976104 complement(470531..472396) 1 NC_015844.1 This conserved protein contains four type-III fibronectin (FN3) domains. Contains also a C-terminal domain of unknown function found in Fibrobacter succinogenes, Chlorobium tepidum and Bacteroides thetaiotaomicron. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Family membership; fibronectin type-III repeat-containing protein 472396 10976104 zobellia_354 Zobellia galactanivorans fibronectin type-III repeat-containing protein YP_004734819.1 470531 R 63186 CDS YP_004734820.1 340616367 10976111 complement(473111..475036) 1 NC_015844.1 Alpha-glucosidases catalyse the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose. Involved in carbohydrate metabolism, notably in starch degradation; Belongs to the family 97 of glycoside hydrolases (GH97); Lipoprotein signal peptide cleaved between the residues 28 and 29; Localized in the outer membrane; High confidence in function and specificity; alpha-glucosidase 475036 10976111 zobellia_355 Zobellia galactanivorans alpha-glucosidase YP_004734820.1 473111 R 63186 CDS YP_004734821.1 340616368 10976119 complement(475126..476721) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a Lipocalin signature involved in the transport of small hydrophobic molecules such as steroids, bilins, retinoids, and lipids; Contains a lipoprotein signal peptide cleaved between the residues 20 and 21; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 476721 10976119 zobellia_356 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734821.1 475126 R 63186 CDS YP_004734822.1 340616369 10976129 complement(476734..480243) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension that probably interacts with an anti-sigma factor (Secretin/TonB (STN) domain), would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (146-220) and a Plug module (236-371) acting as the channel gate; The signal peptide is cleaved between the residue 27 and 28; Family membership; TonB-dependent transducer 480243 10976129 zobellia_357 Zobellia galactanivorans TonB-dependent transducer YP_004734822.1 476734 R 63186 CDS YP_004734823.1 340616370 10976138 complement(480420..481460) 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 481460 10976138 zobellia_358 Zobellia galactanivorans anti-sigma factor YP_004734823.1 480420 R 63186 CDS YP_004734824.1 340616371 10976146 complement(481788..482366) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 482366 10976146 zobellia_359 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004734824.1 481788 R 63186 CDS YP_004734825.1 340616372 10976157 complement(482372..485698) 1 NC_015844.1 Contains four tetratrico peptide repeats (TPRs). The TPR motif consists of 316 tandem-repeats of 34 amino acids residues. It adopts a helixturnhelix arrangement, with adjacent TPR motifs packing in a parallel fashion, resulting in a spiral of repeating anti-parallel alpha-helices. TPRs mediate proteinprotein interactions; Localized in the cytoplasm.; hypothetical protein 485698 10976157 zobellia_360 Zobellia galactanivorans hypothetical protein YP_004734825.1 482372 R 63186 CDS YP_004734826.1 340616373 10976166 complement(485733..485828) 1 NC_015844.1 Hypothetical protein; hypothetical protein 485828 10976166 zobellia_361 Zobellia galactanivorans hypothetical protein YP_004734826.1 485733 R 63186 CDS YP_004734827.1 340616374 10976176 485942..486784 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 486784 10976176 zobellia_362 Zobellia galactanivorans AraC family transcriptional regulator YP_004734827.1 485942 D 63186 CDS YP_004734828.1 340616375 10976183 487749..490580 1 NC_015844.1 Protein that consists of an N-terminal periplasmic beta-propeller followed by a C-terminal cytoplasmic domain containing a LuxR-type HTH domain acting as transcrptionnal regulator. A transmembrane segment is present between these two domains. Signal peptide cleaved between the residues 28 and 29; Localized in the cytoplasmic membrane; Family membership; ligand-binding sensor protein 490580 10976183 zobellia_363 Zobellia galactanivorans ligand-binding sensor protein YP_004734828.1 487749 D 63186 CDS YP_004734829.1 340616376 10976192 490884..493958 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (31-104) and the Plug module (120-230) acting as a channel gate; The signal peptide is cleaved between the residues 27 and 28; Family membership; TonB-dependent Receptor 493958 10976192 zobellia_364 Zobellia galactanivorans TonB-dependent Receptor YP_004734829.1 490884 D 63186 CDS YP_004734830.1 340616377 10976201 493972..495576 1 NC_015844.1 Protein probably involved in nutrient binding. This sequence corresponds to the N-terminal domain found in the proteins belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 25 and 26; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 495576 10976201 zobellia_365 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734830.1 493972 D 63186 CDS YP_004734831.1 340616378 10976208 495668..496450 1 NC_015844.1 Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols; Signal peptide of lipoprotein cleaved between the residues 15 and 16; Localized in the outer membrane; High confidence in function and specificity; glycerophosphoryl diester phosphodiesterase 496450 10976208 zobellia_366 Zobellia galactanivorans glycerophosphoryl diester phosphodiesterase YP_004734831.1 495668 D 63186 CDS YP_004734832.1 340616379 10976213 496534..497424 1 NC_015844.1 Endo-1,3-beta-glucanase (Laminarinase) hydrolyzes the 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans. Belongs to the family 16 of glycoside hydrolases (GH16). Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the cytoplasmic membrane; High confidence in function and specificity; endo-1,3-beta-glucanase 497424 lamB 10976213 lamB Zobellia galactanivorans endo-1,3-beta-glucanase YP_004734832.1 496534 D 63186 CDS YP_004734833.1 340616380 10978073 complement(497815..499938) 1 NC_015844.1 The Sus (starch utilization system) proteins are involved in the starch catabolism; The SusB protein is an alpha-glucosidase that hydrolyzes the alpha-1,4 linkages of maltose and maltotriose and the alpha-1,4 and alpha-1,6 linkages of the panose; It belongs to the family 97 of glycoside hydrolases; Signal peptide cleaved between the residue 24 and 25; Localized in the periplasmic space; High confidence in function and specificity; alpha-glucosidase 499938 susB 10978073 susB Zobellia galactanivorans alpha-glucosidase YP_004734833.1 497815 R 63186 CDS YP_004734834.1 340616381 10978630 complement(500010..501443) 1 NC_015844.1 SusA is a monomeric enzyme that endohydrolyses the 1,4-alpha-D-glucosidic linkages in starch, glycogen and related polysaccharides and oligosaccharides in a random manner. Reducing groups are liberated in the alpha-configuration; Belongs to the glycosyde hydrolase 13 family (GH13); Binds one calcium ion per subunit; Signal peptide of lipoprotein cleaved between the residues 17 and 18; Localized in the outer membrane; High confidence in function and specificity; alpha-amylase 501443 susA 10978630 susA Zobellia galactanivorans alpha-amylase YP_004734834.1 500010 R 63186 CDS YP_004734835.1 340616382 10978629 complement(501524..502672) 1 NC_015844.1 The Sus (starch utilization system) proteins probably are involved in the starch catabolism; Contains a putatif starch binding domain (CBM20); Signal peptide of lipoprotein cleaved between the residues 19 and 20; Localized in the outer membrane; Function unclear; starch utilization lipoprotein 502672 susE 10978629 susE Zobellia galactanivorans starch utilization lipoprotein YP_004734835.1 501524 R 63186 CDS YP_004734836.1 340616383 10978633 complement(502685..504310) 1 NC_015844.1 The Sus (starch utilization system) proteins are involved in the starch catabolism; The SusD protein seems involved in starch binding and belongs to the SusD/RagB family; The Genes of this family are very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Family membership; starch utilization lipoprotein 504310 susD 10978633 susD Zobellia galactanivorans starch utilization lipoprotein YP_004734836.1 502685 R 63186 CDS YP_004734837.1 340616384 10978632 complement(504321..507227) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Possibly involved in the uptake of starch; Contains a carboxypeptidase regulatory domain (22-95) and the Plug module (111-227) acting as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 507227 susC 10978632 susC Zobellia galactanivorans TonB-dependent Receptor YP_004734837.1 504321 R 63186 CDS YP_004734838.1 340616385 10978631 complement(507906..510407) 1 NC_015844.1 Conserved protein containing a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; hypothetical protein 510407 10978631 zobellia_373 Zobellia galactanivorans hypothetical protein YP_004734838.1 507906 R 63186 CDS YP_004734839.1 340616386 10976255 complement(510505..513480) 1 NC_015844.1 Conserved lipoprotein that seems to contain, in its central part, three BON (bacterial OsmY and nodulation) domains that are likely to be a phospholipid-binding domain that is involved in osmotic-shock protection and other cell-membrane-localized processes; Signal peptide cleaved between the residues 20 and 21; localized in the outer membrane; hypothetical protein 513480 10976255 zobellia_374 Zobellia galactanivorans hypothetical protein YP_004734839.1 510505 R 63186 CDS YP_004734840.1 340616387 10976262 complement(513501..513992) 1 NC_015844.1 TraO is part of a conjugative transposon and is predicted to be involved in its transfer. Contains a signal peptide cleaved between the residues 24 and 25. Localized in the periplasmic space.; Function unclear; conjugative transposon protein TraO 513992 traO 10976262 traO Zobellia galactanivorans conjugative transposon protein TraO YP_004734840.1 513501 R 63186 CDS YP_004734841.1 340616388 10978683 complement(514040..515062) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 32 and 33; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 515062 10978683 zobellia_376 Zobellia galactanivorans lipoprotein YP_004734841.1 514040 R 63186 CDS YP_004734842.1 340616389 10976280 515353..515616 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 515616 10976280 zobellia_377 Zobellia galactanivorans hypothetical protein YP_004734842.1 515353 D 63186 CDS YP_004734843.1 340616390 10976289 complement(515595..516788) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; hypothetical protein 516788 10976289 zobellia_378 Zobellia galactanivorans hypothetical protein YP_004734843.1 515595 R 63186 CDS YP_004734844.1 340616391 10976293 complement(516882..517064) 1 NC_015844.1 Hypothetical protein; hypothetical protein 517064 10976293 zobellia_379 Zobellia galactanivorans hypothetical protein YP_004734844.1 516882 R 63186 CDS YP_004734845.1 340616392 10976300 complement(517039..517449) 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 517449 10976300 zobellia_380 Zobellia galactanivorans hypothetical protein YP_004734845.1 517039 R 63186 CDS YP_004734846.1 340616393 10976310 517659..518216 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 518216 10976310 zobellia_381 Zobellia galactanivorans hypothetical protein YP_004734846.1 517659 D 63186 CDS YP_004734847.1 340616394 10976318 518365..518487 1 NC_015844.1 Protein fragment found in proteins annotated as transposases; Localized in the cytoplasm; hypothetical protein 518487 10976318 zobellia_382 Zobellia galactanivorans hypothetical protein YP_004734847.1 518365 D 63186 CDS YP_004734848.1 340616395 10976325 complement(518587..519303) 1 NC_015844.1 Thioesterase involved in the biosynthesis of the antibiotic surfactin. Thioesterases are required for the addition of the last amino acid to the peptide antibiotic, thereby forming a cyclic antibiotic; Localized in the cytoplasm; High confidence in function and specificity; surfactin synthetase thioesterase 519303 srfAD 10976325 srfAD Zobellia galactanivorans surfactin synthetase thioesterase YP_004734848.1 518587 R 63186 CDS YP_004734849.1 340616396 10978610 complement(519308..525586) 1 NC_015844.1 Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane.; Specificity unclear; type I polyketide synthase 525586 10978610 zobellia_384 Zobellia galactanivorans type I polyketide synthase YP_004734849.1 519308 R 63186 CDS YP_004734850.1 340616397 10976340 complement(525832..526503) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 526503 10976340 zobellia_385 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004734850.1 525832 R 63186 CDS YP_004734851.1 340616398 10976350 526988..527818 1 NC_015844.1 This protein corresponds to the N-terminal region of a transposase; The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the transposase mutator family; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 527818 10976350 zobellia_386 Zobellia galactanivorans hypothetical protein YP_004734851.1 526988 D 63186 CDS YP_004734852.1 340616399 10976359 527799..528224 1 NC_015844.1 This protein corresponds to the C-terminal region of a transposase. The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the transposase mutator family; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 528224 10976359 zobellia_387 Zobellia galactanivorans hypothetical protein YP_004734852.1 527799 D 63186 CDS YP_004734853.1 340616400 10976364 complement(528244..528669) 1 NC_015844.1 Possible lipoprotein containing a signal peptide cleaved between the residues 16 and 17; Putatively localized in the outer membrane; Hypothetical protein; hypothetical protein 528669 10976364 zobellia_388 Zobellia galactanivorans hypothetical protein YP_004734853.1 528244 R 63186 CDS YP_004734854.1 340616401 10976367 complement(528695..529081) 1 NC_015844.1 Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 529081 10976367 zobellia_389 Zobellia galactanivorans hypothetical protein YP_004734854.1 528695 R 63186 CDS YP_004734855.1 340616402 10976377 complement(529339..529500) 1 NC_015844.1 Hypothetical protein; hypothetical protein 529500 10976377 zobellia_390 Zobellia galactanivorans hypothetical protein YP_004734855.1 529339 R 63186 CDS YP_004734856.1 340616403 10976387 complement(529610..530263) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 530263 10976387 zobellia_391 Zobellia galactanivorans hypothetical protein YP_004734856.1 529610 R 63186 CDS YP_004734857.1 340616404 10976398 complement(530438..530614) 1 NC_015844.1 Hypothetical protein; hypothetical protein 530614 10976398 zobellia_392 Zobellia galactanivorans hypothetical protein YP_004734857.1 530438 R 63186 CDS YP_004734858.1 340616405 10976409 complement(530710..531081) 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 531081 10976409 zobellia_393 Zobellia galactanivorans membrane protein YP_004734858.1 530710 R 63186 CDS YP_004734859.1 340616406 10976420 complement(531078..532109) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 532109 10976420 zobellia_394 Zobellia galactanivorans hypothetical protein YP_004734859.1 531078 R 63186 CDS YP_004734860.1 340616407 10976430 complement(532117..532506) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 532506 10976430 zobellia_395 Zobellia galactanivorans hypothetical protein YP_004734860.1 532117 R 63186 CDS YP_004734861.1 340616408 10976439 complement(532550..533899) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 533899 10976439 zobellia_396 Zobellia galactanivorans hypothetical protein YP_004734861.1 532550 R 63186 CDS YP_004734862.1 340616409 10976445 complement(533918..534370) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 534370 10976445 zobellia_397 Zobellia galactanivorans hypothetical protein YP_004734862.1 533918 R 63186 CDS YP_004734863.1 340616410 10976453 complement(534492..534878) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 534878 10976453 zobellia_398 Zobellia galactanivorans hypothetical protein YP_004734863.1 534492 R 63186 CDS YP_004734864.1 340616411 10976463 complement(535250..536284) 1 NC_015844.1 Conserved protein containing two PKD domains. Features an uncleaved signal peptide. Localized in the cytoplasmic membrane.; Family membership; PKD repeat-containing protein 536284 10976463 zobellia_399 Zobellia galactanivorans PKD repeat-containing protein YP_004734864.1 535250 R 63186 CDS YP_004734865.1 340616412 10976472 536307..536978 1 NC_015844.1 Cysteine peptidase belonging to the family C40. Its exact function is not known. C40 peptidases contain single conserved cysteine and histidine residues that form a catalytic dyad in the order Cys, His. Features a prokaryotic lipoprotein signal peptide cleaved between the residues 27 and 28; Localized in the outer membrane; Specificity unclear; peptidase, family C40 536978 10976472 zobellia_400 Zobellia galactanivorans peptidase, family C40 YP_004734865.1 536307 D 63186 CDS YP_004734866.1 340616413 10976484 536979..537884 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 537884 10976484 zobellia_401 Zobellia galactanivorans hypothetical protein YP_004734866.1 536979 D 63186 CDS YP_004734867.1 340616414 10976491 537891..538757 1 NC_015844.1 Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 538757 10976491 zobellia_402 Zobellia galactanivorans membrane protein YP_004734867.1 537891 D 63186 CDS YP_004734868.1 340616415 10976497 538768..539910 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 539910 10976497 zobellia_403 Zobellia galactanivorans hypothetical protein YP_004734868.1 538768 D 63186 CDS YP_004734869.1 340616416 10976504 539921..540430 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 540430 10976504 zobellia_404 Zobellia galactanivorans membrane protein YP_004734869.1 539921 D 63186 CDS YP_004734870.1 340616417 10976512 540438..542903 1 NC_015844.1 ClpB is a homohexamer that is a part of a stress-induced multi-chaperone system involved in the recovery of the cell from heat-induced damage, in cooperation with dnaK, dnaJ and grpE. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates contributing to the solubilization and refolding of denatured protein aggregates by dnaK; Contains 2 AAA ATPase domains; Localized in the cytoplasm; High confidence in function and specificity; chaperone ClpB 542903 clpB2 10976512 clpB2 Zobellia galactanivorans chaperone ClpB YP_004734870.1 540438 D 63186 CDS YP_004734871.1 340616418 10977651 543087..543521 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 543521 10977651 zobellia_406 Zobellia galactanivorans hypothetical protein YP_004734871.1 543087 D 63186 CDS YP_004734872.1 340616419 10976527 543553..545421 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 545421 10976527 zobellia_407 Zobellia galactanivorans hypothetical protein YP_004734872.1 543553 D 63186 CDS YP_004734873.1 340616420 10976537 545524..547359 1 NC_015844.1 Conserved protein belonging to the Vgr family. The Vgr family proteins are associated with some classes of Rhs elements. Localized in the cytoplasm.; Family membership; Vgr family protein 547359 10976537 zobellia_408 Zobellia galactanivorans Vgr family protein YP_004734873.1 545524 D 63186 CDS YP_004734874.1 340616421 10976546 547372..548232 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 548232 10976546 zobellia_409 Zobellia galactanivorans hypothetical protein YP_004734874.1 547372 D 63186 CDS YP_004734875.1 340616422 10976554 548250..548738 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 548738 10976554 zobellia_410 Zobellia galactanivorans hypothetical protein YP_004734875.1 548250 D 63186 CDS YP_004734876.1 340616423 10976564 548739..550994 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 550994 10976564 zobellia_411 Zobellia galactanivorans hypothetical protein YP_004734876.1 548739 D 63186 CDS YP_004734877.1 340616424 10976573 550998..551618 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 551618 10976573 zobellia_412 Zobellia galactanivorans hypothetical protein YP_004734877.1 550998 D 63186 CDS YP_004734878.1 340616425 10976581 551626..552399 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 552399 10976581 zobellia_413 Zobellia galactanivorans hypothetical protein YP_004734878.1 551626 D 63186 CDS YP_004734879.1 340616426 10976589 552570..553586 1 NC_015844.1 Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 553586 10976589 zobellia_414 Zobellia galactanivorans membrane protein YP_004734879.1 552570 D 63186 CDS YP_004734880.1 340616427 10976595 553635..553865 1 NC_015844.1 Hypothetical protein; Family membership; LemA family protein, N-terminal fragment 553865 10976595 zobellia_415 Zobellia galactanivorans LemA family protein, N-terminal fragment YP_004734880.1 553635 D 63186 CDS YP_004734881.1 340616428 10976602 553823..554194 1 NC_015844.1 Conserved hypothetical protein; Family membership; LemA family protein, C-terminal fragment 554194 10976602 zobellia_416 Zobellia galactanivorans LemA family protein, C-terminal fragment YP_004734881.1 553823 D 63186 CDS YP_004734882.1 340616429 10976612 554130..554540 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 554540 10976612 zobellia_417 Zobellia galactanivorans membrane protein YP_004734882.1 554130 D 63186 CDS YP_004734883.1 340616430 10976620 554548..554652 1 NC_015844.1 Hypothetical protein; hypothetical protein 554652 10976620 zobellia_418 Zobellia galactanivorans hypothetical protein YP_004734883.1 554548 D 63186 CDS YP_004734884.1 340616431 10976629 554789..555691 1 NC_015844.1 Conserved protein containing a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; hypothetical protein 555691 10976629 zobellia_419 Zobellia galactanivorans hypothetical protein YP_004734884.1 554789 D 63186 CDS YP_004734885.1 340616432 10976638 555762..555896 1 NC_015844.1 Hypothetical protein; hypothetical protein 555896 10976638 zobellia_420 Zobellia galactanivorans hypothetical protein YP_004734885.1 555762 D 63186 CDS YP_004734886.1 340616433 10976648 556014..557570 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 557570 10976648 zobellia_421 Zobellia galactanivorans hypothetical protein YP_004734886.1 556014 D 63186 CDS YP_004734887.1 340616434 10976658 557570..558640 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 558640 10976658 zobellia_422 Zobellia galactanivorans hypothetical protein YP_004734887.1 557570 D 63186 CDS YP_004734888.1 340616435 10976666 558669..558812 1 NC_015844.1 Hypothetical protein; hypothetical protein 558812 10976666 zobellia_423 Zobellia galactanivorans hypothetical protein YP_004734888.1 558669 D 63186 CDS YP_004734889.1 340616436 10976674 complement(558809..559597) 1 NC_015844.1 Sequence representing the C-terminal part of transposase that could be an insertion sequence (IS). The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 8 of transposases; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 559597 10976674 zobellia_424 Zobellia galactanivorans hypothetical protein YP_004734889.1 558809 R 63186 CDS YP_004734890.1 340616437 10976684 complement(559672..559938) 1 NC_015844.1 Sequence representing the N-terminal part of transposase that could be an insertion sequence (IS). The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Contains a helix-turn-helix domain; Belongs to the family 8 of transposases; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 559938 10976684 zobellia_425 Zobellia galactanivorans hypothetical protein YP_004734890.1 559672 R 63186 CDS YP_004734891.1 340616438 10976691 560146..560250 1 NC_015844.1 Hypothetical protein; hypothetical protein 560250 10976691 zobellia_426 Zobellia galactanivorans hypothetical protein YP_004734891.1 560146 D 63186 CDS YP_004734892.1 340616439 10976699 560265..560381 1 NC_015844.1 Hypothetical protein; hypothetical protein 560381 10976699 zobellia_427 Zobellia galactanivorans hypothetical protein YP_004734892.1 560265 D 63186 CDS YP_004734893.1 340616440 10976703 560448..560540 1 NC_015844.1 Hypothetical protein; hypothetical protein 560540 10976703 zobellia_428 Zobellia galactanivorans hypothetical protein YP_004734893.1 560448 D 63186 CDS YP_004734894.1 340616441 10976711 560528..561520 1 NC_015844.1 Contains two transmembrane segments; Probably localized in the cytoplasmic membrane; hypothetical protein 561520 10976711 zobellia_429 Zobellia galactanivorans hypothetical protein YP_004734894.1 560528 D 63186 CDS YP_004734895.1 340616442 10976720 561659..561793 1 NC_015844.1 Hypothetical protein; hypothetical protein 561793 10976720 zobellia_430 Zobellia galactanivorans hypothetical protein YP_004734895.1 561659 D 63186 CDS YP_004734896.1 340616443 10976731 561787..562662 1 NC_015844.1 Contains two transmembrane segments; Pobably localized in the cytoplasmic membrane; hypothetical protein 562662 10976731 zobellia_431 Zobellia galactanivorans hypothetical protein YP_004734896.1 561787 D 63186 CDS YP_004734897.1 340616444 10976741 562671..563546 1 NC_015844.1 Contains two transmenbrane segments; Probably localized in the cytoplasmic membrane; hypothetical protein 563546 10976741 zobellia_432 Zobellia galactanivorans hypothetical protein YP_004734897.1 562671 D 63186 CDS YP_004734898.1 340616445 10976761 563996..564358 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 564358 10976761 zobellia_434 Zobellia galactanivorans hypothetical protein YP_004734898.1 563996 D 63186 CDS YP_004734899.1 340616446 10976772 564362..564508 1 NC_015844.1 Hypothetical protein; hypothetical protein 564508 10976772 zobellia_435 Zobellia galactanivorans hypothetical protein YP_004734899.1 564362 D 63186 CDS YP_004734900.1 340616447 10976778 564512..565438 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 565438 10976778 zobellia_436 Zobellia galactanivorans hypothetical protein YP_004734900.1 564512 D 63186 CDS YP_004734901.1 340616448 10976789 565711..566451 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 566451 10976789 zobellia_437 Zobellia galactanivorans hypothetical protein YP_004734901.1 565711 D 63186 CDS YP_004734902.1 340616449 10976798 566551..567105 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 567105 10976798 zobellia_438 Zobellia galactanivorans hypothetical protein YP_004734902.1 566551 D 63186 CDS YP_004734903.1 340616450 10976808 567172..568002 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 568002 10976808 zobellia_439 Zobellia galactanivorans hypothetical protein YP_004734903.1 567172 D 63186 CDS YP_004734904.1 340616451 10976815 568018..568536 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 568536 10976815 zobellia_440 Zobellia galactanivorans hypothetical protein YP_004734904.1 568018 D 63186 CDS YP_004734905.1 340616452 10976822 568548..569042 1 NC_015844.1 Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; hypothetical protein 569042 10976822 zobellia_441 Zobellia galactanivorans hypothetical protein YP_004734905.1 568548 D 63186 CDS YP_004734906.1 340616453 10976830 569108..569722 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 569722 10976830 zobellia_442 Zobellia galactanivorans membrane protein YP_004734906.1 569108 D 63186 CDS YP_004734907.1 340616454 10976837 569780..570466 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 570466 10976837 zobellia_443 Zobellia galactanivorans hypothetical protein YP_004734907.1 569780 D 63186 CDS YP_004734908.1 340616455 10976847 570610..571047 1 NC_015844.1 Signal peptide cleaved between the residues 15 and 16: Lipoprotein localized in the outer membrane; Hypothetical protein; hypothetical protein 571047 10976847 zobellia_444 Zobellia galactanivorans hypothetical protein YP_004734908.1 570610 D 63186 CDS YP_004734909.1 340616456 10976857 571368..571763 1 NC_015844.1 Contains one transmebrane segment; Signal peptide cleaved between the residues 19 and 20; Protein localized in the cytoplasmic membrane; hypothetical protein 571763 10976857 zobellia_445 Zobellia galactanivorans hypothetical protein YP_004734909.1 571368 D 63186 CDS YP_004734910.1 340616457 10976867 complement(571735..571869) 1 NC_015844.1 Hypothetical protein; hypothetical protein 571869 10976867 zobellia_446 Zobellia galactanivorans hypothetical protein YP_004734910.1 571735 R 63186 CDS YP_004734911.1 340616458 10976878 572135..573184 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 573184 10976878 zobellia_447 Zobellia galactanivorans membrane protein YP_004734911.1 572135 D 63186 CDS YP_004734912.1 340616459 10976887 573196..573756 1 NC_015844.1 Conserved protein belonging to the LemA family. In Listeria monocytogenes LemA corresponds to a H2-M3-restricted epitope. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain; Localized in the cytoplasmic membrane; Family membership; LemA family protein 573756 10976887 zobellia_448 Zobellia galactanivorans LemA family protein YP_004734912.1 573196 D 63186 CDS YP_004734913.1 340616460 10976894 573740..574126 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 574126 10976894 zobellia_449 Zobellia galactanivorans membrane protein YP_004734913.1 573740 D 63186 CDS YP_004734914.1 340616461 10976902 574235..575023 1 NC_015844.1 Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 575023 10976902 zobellia_450 Zobellia galactanivorans membrane protein YP_004734914.1 574235 D 63186 CDS YP_004734915.1 340616462 10976913 575204..575473 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Hypothetical protein; hypothetical protein 575473 10976913 zobellia_451 Zobellia galactanivorans hypothetical protein YP_004734915.1 575204 D 63186 CDS YP_004734916.1 340616463 10976922 complement(575619..576638) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 576638 10976922 zobellia_452 Zobellia galactanivorans periplasmic protein YP_004734916.1 575619 R 63186 CDS YP_004734917.1 340616464 10976927 complement(577319..577894) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the cytoplasmic and/or outer membranes; Hypothetical protein; hypothetical protein 577894 10976927 zobellia_453 Zobellia galactanivorans hypothetical protein YP_004734917.1 577319 R 63186 CDS YP_004734918.1 340616465 10976931 complement(577901..580672) 1 NC_015844.1 Conserved protein belonging to the DUF608 family; Contains a signal peptide cleaved between the residues 37 and 38; Localized in the periplasmic space; hypothetical protein 580672 10976931 zobellia_454 Zobellia galactanivorans hypothetical protein YP_004734918.1 577901 R 63186 CDS YP_004734919.1 340616466 10976939 complement(580708..581559) 1 NC_015844.1 Containsa signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 581559 10976939 zobellia_455 Zobellia galactanivorans hypothetical protein YP_004734919.1 580708 R 63186 CDS YP_004734920.1 340616467 10976947 complement(581650..584118) 1 NC_015844.1 Conserved protein belonging to the DUF608 family; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; hypothetical protein 584118 10976947 zobellia_456 Zobellia galactanivorans hypothetical protein YP_004734920.1 581650 R 63186 CDS YP_004734921.1 340616468 10976953 complement(584203..585897) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 20 and 21; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 585897 10976953 zobellia_457 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004734921.1 584203 R 63186 CDS YP_004734922.1 340616469 10976960 complement(585914..589237) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (127-201), and a Plug module (217-324) acting as the channel gate; The signal peptide is cleaved between the residue 29 and 30; Family membership; TonB-dependent transducer 589237 10976960 zobellia_458 Zobellia galactanivorans TonB-dependent transducer YP_004734922.1 585914 R 63186 CDS YP_004734923.1 340616470 10976967 complement(589446..590609) 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 590609 10976967 zobellia_459 Zobellia galactanivorans anti-sigma factor YP_004734923.1 589446 R 63186 CDS YP_004734924.1 340616471 10976977 590721..591323 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 591323 10976977 zobellia_460 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004734924.1 590721 D 63186 CDS YP_004734925.1 340616472 10976986 complement(592065..595595) 1 NC_015844.1 Contains C-terminal PKD repeats and a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein; PKD repeats containing lipoprotein 595595 10976986 zobellia_461 Zobellia galactanivorans PKD repeats containing lipoprotein YP_004734925.1 592065 R 63186 CDS YP_004734926.1 340616473 10974031 complement(596783..598831) 1 NC_015844.1 This protein is a putative receptor with a N-terminal extracellular domain, a central membrane domain and a C-terminal metal-dependent phosphohydrolase domain. Its exact function is unknown; Contains a N-terminal transmembrane helix and seven transmembrane helices in the central region; Localized in the cytoplamic membrane; Function unclear; hypothetical protein 598831 yqfF 10974031 yqfF Zobellia galactanivorans hypothetical protein YP_004734926.1 596783 R 63186 CDS YP_004734927.1 340616474 10978790 598952..600124 1 NC_015844.1 Acetyl-CoA acetyltransferase is specific for the thiolysis of acetoacetyl-CoA and involved in biosynthetic pathways such as poly beta-hydroxybutyrate synthesis or mevalonate biogenesis. Localized in the cytoplasm.; High confidence in function and specificity; acetyl-CoA acetyltransferase 600124 thlA 10978790 thlA Zobellia galactanivorans acetyl-CoA acetyltransferase YP_004734927.1 598952 D 63186 CDS YP_004734928.1 340616475 10978655 600149..600901 1 NC_015844.1 Dipeptidyl peptidase hydrolyzes gamma-D-Glu-L-(meso)A2pm linkages only in those peptide units that have a free N-terminal L-alanine. It is involved in peptidoglycan metabolism. Belongs to the family 40 of the cysteine peptidases. These peptidases contain single conserved cysteine and histidine residues that form a putative catalytic dyad in the order Cys, His. Features also a bacterial SH3 domain in the N-terminal region.; High confidence in function and specificity; dipeptidyl peptidase 600901 10978655 zobellia_466 Zobellia galactanivorans dipeptidyl peptidase YP_004734928.1 600149 D 63186 CDS YP_004734929.1 340616476 10977026 complement(601277..602539) 1 NC_015844.1 Conserved protein containing three tetratrico peptide repeats (TPRs). TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Function unclear; hypothetical protein 602539 10977026 zobellia_467 Zobellia galactanivorans hypothetical protein YP_004734929.1 601277 R 63186 CDS YP_004734930.1 340616477 10977036 complement(602583..605123) 1 NC_015844.1 DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings. It is a A2B2 heterotetramer. The A subunit being responsible for DNA breakage and rejoining, the B chain catalyzing ATP hydrolysis; Belongs to the type-II topoisomerase family, IIA subfamily; Localized in the cytoplasm; High confidence in function and specificity; DNA gyrase subunit A 605123 gyrA 10977036 gyrA Zobellia galactanivorans DNA gyrase subunit A YP_004734930.1 602583 R 63186 CDS YP_004734931.1 340616478 10977958 605383..607929 1 NC_015844.1 ClpC may interact with a clpP-like protease involved in degradation of denatured proteins and could be required for cell growth at high temperature; Contains 2 Clp amino terminal domains that function as a substrate-discriminating domain, 2 AAA ATPase domains and 1 UVR domain; Localized in the cytoplasm; High confidence in function and specificity; chaperone ClpC 607929 clpC 10977958 clpC Zobellia galactanivorans chaperone ClpC YP_004734931.1 605383 D 63186 CDS YP_004734932.1 340616479 10977652 608132..608533 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 608533 10977652 zobellia_470 Zobellia galactanivorans hypothetical protein YP_004734932.1 608132 D 63186 CDS YP_004734933.1 340616480 10977060 complement(608609..610162) 1 NC_015844.1 Conserved modular protein Localized in the cytoplasm; hypothetical protein 610162 10977060 zobellia_471 Zobellia galactanivorans hypothetical protein YP_004734933.1 608609 R 63186 CDS YP_004734934.1 340616481 10977066 610540..612984 1 NC_015844.1 ThrA is a fusion-protein between aspartate kinase I (N-terminal) and homoserine dehydrogenase I (C-terminal) involved in L-Lysine and L-threonine biosynthesis pathways. Aspartate kinase I converts L-aspartate to 4-phospho-L-aspartate and belongs to the amino acid kinase family. Homoserine dehydrogenase I converts the L-homoserine to L-aspartate 4-semialdehyde. Homoserine dehydrogenase I is composed of a substrate-binding domain belonging to Homoserine dehydrogenase family and a NAD-binding domain (Rossman fold). ThrA features also two central regulatory ACT domains; Localized in the cytoplasm; High confidence in function and specificity; aspartate kinase I / Homoserine dehydrogenase I 612984 thrA 10977066 thrA Zobellia galactanivorans aspartate kinase I / Homoserine dehydrogenase I YP_004734934.1 610540 D 63186 CDS YP_004734935.1 340616482 10978656 612987..613910 1 NC_015844.1 Homoserine kinase is involved in the threonine biosynthesis pathway. It converts, in presence of ATP, the L-homoserine to O-phospho-L-homoserine. Belongs to the GHMP kinases family; Localized in the cytoplasm; High confidence in function and specificity; homoserine kinase 613910 thrB 10978656 thrB Zobellia galactanivorans homoserine kinase YP_004734935.1 612987 D 63186 CDS YP_004734936.1 340616483 10978657 613910..615205 1 NC_015844.1 Threonine synthase is involved in the threonine biosynthesis pathway. It converts the O-phospho-L-homoserine to L-threonine. Belongs to the Pyridoxal-phosphate dependent enzyme family; Localized in the cytoplasm; High confidence in function and specificity; threonine synthase 615205 thrC 10978657 thrC Zobellia galactanivorans threonine synthase YP_004734936.1 613910 D 63186 CDS YP_004734937.1 340616484 10978659 complement(615242..616891) 1 NC_015844.1 Xaa-Pro aminopeptidase catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Belongs to the family M24 of the metallopeptidases. PepP requires two co-catalytic ions of manganese. Features a signal peptide cleaved between the residues 31 and 32. Localized in the periplasm.; High confidence in function and specificity; Xaa-Pro aminopeptidase, family M24 616891 pepP1 10978659 pepP1 Zobellia galactanivorans Xaa-Pro aminopeptidase, family M24 YP_004734937.1 615242 R 63186 CDS YP_004734938.1 340616485 10978327 617001..618086 1 NC_015844.1 The glycine cleavage system is composed of four proteins: P, T, L and H. The T protein is the aminomethyltransferase. It catalyzes the reaction: [Protein]-S8-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. Localized in the cytoplasm.; High confidence in function and specificity; glycine cleavage system T protein 618086 gcvT 10978327 gcvT Zobellia galactanivorans glycine cleavage system T protein YP_004734938.1 617001 D 63186 CDS YP_004734939.1 340616486 10977885 618119..618946 1 NC_015844.1 Conserved protein belonging to the RmlD substrate binding domain family. In RlmB, this domain is responsible for binding a sugar nucleotide. The function of this protein is unclear; Localized in the cytoplasm; Family membership; RmlD substrate binding domain family protein 618946 10977885 zobellia_477 Zobellia galactanivorans RmlD substrate binding domain family protein YP_004734939.1 618119 D 63186 CDS YP_004734940.1 340616487 10977106 619037..619324 1 NC_015844.1 Pterin-4-alpha-carbinolamine dehydratase is involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. It catalyzes the the dehydration of 4a-hydroxytetrahydrobiopterins. Localized in the cytoplasm.; High confidence in function and specificity; Pterin-4-alpha-carbinolamine dehydratase 619324 pcbD 10977106 pcbD Zobellia galactanivorans Pterin-4-alpha-carbinolamine dehydratase YP_004734940.1 619037 D 63186 CDS YP_004734941.1 340616488 10978310 619475..620185 1 NC_015844.1 Conserved protein belonging to the DUF28 family; Localized in the cytoplasm; Family membership; hypothetical protein 620185 10978310 zobellia_479 Zobellia galactanivorans hypothetical protein YP_004734941.1 619475 D 63186 CDS YP_004734942.1 340616489 10977114 complement(620302..620841) 1 NC_015844.1 Conserved protein belonging to the acyltransferase family. Its exact function is unknown; Localized in the cytoplasm; Family membership; acyltransferase family protein 620841 10977114 zobellia_480 Zobellia galactanivorans acyltransferase family protein YP_004734942.1 620302 R 63186 CDS YP_004734943.1 340616490 10977116 complement(620920..622047) 1 NC_015844.1 Iron-containing alcohol dehydrogenase catalyzes the reversible oxidation of ethanol to acetaldehyde with the concomitant reduction of NAD. Its exact specificity is unclear. It uses NAD as cofactor. Localized in the cytoplasm.; Specificity unclear; iron-containing alcohol dehydrogenase 622047 10977116 zobellia_481 Zobellia galactanivorans iron-containing alcohol dehydrogenase YP_004734943.1 620920 R 63186 CDS YP_004734944.1 340616491 10977117 complement(622052..622753) 1 NC_015844.1 N-Acylneuraminate-9-phosphatase (Neu5Ac-9-Pase)is involved in the aminosugar metabolism. It converts the N-acylneuraminate 9-phosphate to N-acylneuraminate. It binds one magnesium ion as cofactor; Belongs to the haloacid dehalogenase-like hydrolase superfamily; Localized in the cytoplasm; High confidence in function and specificity; N-acylneuraminate-9-phosphatase 622753 nanP 10977117 nanP Zobellia galactanivorans N-acylneuraminate-9-phosphatase YP_004734944.1 622052 R 63186 CDS YP_004734945.1 340616492 10978235 complement(622744..623457) 1 NC_015844.1 The 3-Deoxy-manno-octulosonate cytidylyltransferase, also known as CMP-KDO synthetase, activates KDO (a 8-carbon sugar) required for incorporation into bacterial lipopolysaccharide in Gram- negative bacteria; It binds one magnesium ion as cofactor; Localized in the cytoplasm.; High confidence in function and specificity; 3-deoxy-manno-octulosonate cytidylyltransferase 623457 kdsB 10978235 kdsB Zobellia galactanivorans 3-deoxy-manno-octulosonate cytidylyltransferase YP_004734945.1 622744 R 63186 CDS YP_004734946.1 340616493 10978056 complement(623564..624133) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 624133 10978056 zobellia_484 Zobellia galactanivorans membrane protein YP_004734946.1 623564 R 63186 CDS YP_004734947.1 340616494 10977118 complement(624239..625672) 1 NC_015844.1 The Exonuclease V is a multifunctional nuclease required for efficient DNA repair. It catalyzes the unwinding of double-stranded DNA and the cleavage of single-stranded DNA and it stimulates local genetic recombination. All of these activities require concomitant hydrolysis of ATP; Belongs to the helicase family, UvrD subfamily; Localized in the cytoplasm; High confidence in function and specificity; exodeoxyribonuclease V subunit alpha 625672 recD 10977118 recD Zobellia galactanivorans exodeoxyribonuclease V subunit alpha YP_004734947.1 624239 R 63186 CDS YP_004734948.1 340616495 10978441 625780..626433 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 626433 10978441 zobellia_486 Zobellia galactanivorans hypothetical protein YP_004734948.1 625780 D 63186 CDS YP_004734949.1 340616496 10977119 626408..627241 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 627241 10977119 zobellia_487 Zobellia galactanivorans hypothetical protein YP_004734949.1 626408 D 63186 CDS YP_004734950.1 340616497 10977120 627241..627795 1 NC_015844.1 Conserved hypothetical protein predicted as a methyltransferase; Localized in the cytoplasm; hypothetical protein 627795 10977120 zobellia_488 Zobellia galactanivorans hypothetical protein YP_004734950.1 627241 D 63186 CDS YP_004734951.1 340616498 10977121 628240..630063 1 NC_015844.1 The tau chain of DNA polymerase III is a scaffold to help in the dimerizaton of the alpha chain in core enzyme. It is a 'motor' ATPase. The gamma chain is a part of the clamp loader and seems to interact with the delta chain to transfer the beta chain on the DNA. It is a 'motor' ATPase that has the active site for the clamp loader. The gamma chain is the product of the same gene as the tau subunit and has the same amino-terminus; The DNA polymerase III or replicase is responsible for most of the replicative synthesis in bacteria. It also exhibits a 3' to 5' exonuclease proofreading activity; Localized in the cytoplasm; High confidence in function and specificity; DNA polymerase III subunit gamma/tau 630063 dnaX 10977121 dnaX Zobellia galactanivorans DNA polymerase III subunit gamma/tau YP_004734951.1 628240 D 63186 CDS YP_004734952.1 340616499 10977757 complement(630052..630414) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 630414 10977757 zobellia_490 Zobellia galactanivorans membrane protein YP_004734952.1 630052 R 63186 CDS YP_004734953.1 340616500 10977123 complement(630411..631790) 1 NC_015844.1 Type I phosphodiesterase catalyzes the cleavage of phosphodiester and phosphosulfate bonds in various substrates such as NAD, deoxynucleotides and nucleotide sugars. The exact specificity of this enzyme is not known; Localized in the cytoplasm; Family membership; type I phosphodiesterase 631790 10977123 zobellia_491 Zobellia galactanivorans type I phosphodiesterase YP_004734953.1 630411 R 63186 CDS YP_004734954.1 340616501 10977124 complement(631794..632987) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 632987 10977124 zobellia_492 Zobellia galactanivorans hypothetical protein YP_004734954.1 631794 R 63186 CDS YP_004734955.1 340616502 10977125 complement(632989..634149) 1 NC_015844.1 3-Dehydroquinate synthase is involved in the biosynthesis of aromatic amino acids. It catalyzes the second step of the shikimate pathway, the formation of dehydroquinate and orthophosphate from 3-deoxy-D-arabino heptulosonic 7 phosphate. It forms a monomer and binds NAD and divalent metal cation as cofactors. Localized in the cytoplasm.; High confidence in function and specificity; 3-dehydroquinate synthase 634149 aroB1 10977125 aroB1 Zobellia galactanivorans 3-dehydroquinate synthase YP_004734955.1 632989 R 63186 CDS YP_004734956.1 340616503 10977544 complement(634184..635086) 1 NC_015844.1 Conserved protein belonging to the UbiA prenyltransferase family, which includes various prenyltransferases, but also cytochrome C oxidase assembly factor. The exact function of this protein is unclear; Contains nine transmembrane helices. Localized in the cytoplasmic membrane; Family membership; UbiA prenyltransferase family protein 635086 10977544 zobellia_494 Zobellia galactanivorans UbiA prenyltransferase family protein YP_004734956.1 634184 R 63186 CDS YP_004734957.1 340616504 10977126 complement(635086..635994) 1 NC_015844.1 Conserved protein belonging to the TatD family. These enzymes adopt a TIM barrel fold; Localized in the cytoplasm; Family membership; TatD family protein 635994 10977126 zobellia_495 Zobellia galactanivorans TatD family protein YP_004734957.1 635086 R 63186 CDS YP_004734958.1 340616505 10977127 complement(635996..636853) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 636853 10977127 zobellia_496 Zobellia galactanivorans hypothetical protein YP_004734958.1 635996 R 63186 CDS YP_004734959.1 340616506 10977128 637032..637613 1 NC_015844.1 MiaE is involved in the production of the modified nucleoside 2-methylthio-cis-ribozeatin (MS[2]IO[6]A) found in some tRNAs. Catalyzes the oxygen-dependent transformation of MS[2]I[6]A into MS[2]IO[6]A. Localized in the cytoplasm.; High confidence in function and specificity; tRNA-(ms[2]io[6]A)-hydroxylase 637613 miaE 10977128 miaE Zobellia galactanivorans tRNA-(ms[2]io[6]A)-hydroxylase YP_004734959.1 637032 D 63186 CDS YP_004734960.1 340616507 10978160 complement(637654..639759) 1 NC_015844.1 Polyphosphate kinase 1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to histidine residues through a N-P bond. Localized in the cytoplasm.; High confidence in function and specificity; polyphosphate kinase 1 639759 ppk1 10978160 ppk1 Zobellia galactanivorans polyphosphate kinase 1 YP_004734960.1 637654 R 63186 CDS YP_004734961.1 340616508 10978373 complement(639760..640245) 1 NC_015844.1 Conserved protein belonging to the phosphoglycerate mutase family. Its exact function is unclear. Localized in the cytoplasm.; Family membership; phosphoglycerate mutase family protein 640245 10978373 zobellia_499 Zobellia galactanivorans phosphoglycerate mutase family protein YP_004734961.1 639760 R 63186 CDS YP_004734962.1 340616509 10977129 complement(640306..640953) 1 NC_015844.1 Pyridoxamine 5'-phosphate oxidase is involved in the vitamine B6 metabolism. It oxidizes pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). It forms a homodimer and binds one FMN as cofactor per subunit. Localized in the cytoplasm.; High confidence in function and specificity; pyridoxamine 5'-phosphate oxidase 640953 pdxH1 10977129 pdxH1 Zobellia galactanivorans pyridoxamine 5'-phosphate oxidase YP_004734962.1 640306 R 63186 CDS YP_004734963.1 340616510 10978320 complement(641023..641928) 1 NC_015844.1 Ribonuclease Z is a zinc phosphodiesterase, which displays a tRNA 3'-processing endonuclease activity. It is probably involved in tRNA maturation, by removing a 3' trailer from precursor tRNA; It catalyses a endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule; Binds 2 zinc ions; Belongs to the metallo-beta-lactamase family; Localized in the cytoplasm; High confidence in function and specificity; ribonuclease Z 641928 rrnA 10978320 rrnA Zobellia galactanivorans ribonuclease Z YP_004734963.1 641023 R 63186 CDS YP_004734964.1 340616511 10978554 complement(641936..642409) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 642409 10978554 zobellia_502 Zobellia galactanivorans hypothetical protein YP_004734964.1 641936 R 63186 CDS YP_004734965.1 340616512 10977132 complement(642406..642738) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 642738 10977132 zobellia_503 Zobellia galactanivorans hypothetical protein YP_004734965.1 642406 R 63186 CDS YP_004734966.1 340616513 10977133 complement(642746..643672) 1 NC_015844.1 Aspartate carbamoyltransferase catalyzes the conversion of aspartate and carbamoyl phosphate to carbamoylaspartate (). This is the second step in the de novo biosynthesis of pyrimidine nucleotides; Localized in the cytoplasm; High confidence in function and specificity; aspartate carbamoyltransferase 643672 pyrB 10977133 pyrB Zobellia galactanivorans aspartate carbamoyltransferase YP_004734966.1 642746 R 63186 CDS YP_004734967.1 340616514 10978417 complement(643675..644214) 1 NC_015844.1 PyrR regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. It forms in equilibrium a homodimer and a homohexamer. Localized in the cytoplasm.; High confidence in function and specificity; bifunctional protein pyrR 644214 pyrR1 10978417 pyrR1 Zobellia galactanivorans bifunctional protein pyrR YP_004734967.1 643675 R 63186 CDS YP_004734968.1 340616515 10978424 complement(644445..646277) 1 NC_015844.1 The ribosomal protein S1 is a part of the ribosomal small subunit. It binds mRNA through six S1 domains with some degree of sequence specificity, facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno sequence; Some nascent polypeptide chains are able to cross-link to this protein in situ. Can be cross-linked to mRNA in the ribosome; Contains 6 S1 motif domains found in a large number of RNA-associated proteins; Belongs to the ribosomal protein S1P family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S1 646277 rpsA 10978424 rpsA Zobellia galactanivorans 30S ribosomal protein S1 YP_004734968.1 644445 R 63186 CDS YP_004734969.1 340616516 10978531 646548..646928 1 NC_015844.1 Protein YgaU contains a C-terminal peptidoglycan-binding LysM domain. LysM domains belongs to the family 50 of the carbohydrate binding modules (CBM50). Localized in the cytoplasm.; Family membership; protein YgaU 646928 ygaU 10978531 ygaU Zobellia galactanivorans protein YgaU YP_004734969.1 646548 D 63186 CDS YP_004734970.1 340616517 10978784 complement(646983..647675) 1 NC_015844.1 Cytidylate kinase is involved in pyrimidine nucleotide metabolism. It catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP. Localized in the cytoplasm.; High confidence in function and specificity; cytidylate kinase 647675 cmk 10978784 cmk Zobellia galactanivorans cytidylate kinase YP_004734970.1 646983 R 63186 CDS YP_004734971.1 340616518 10977659 complement(647675..650143) 1 NC_015844.1 Endopeptidase La degrades short-lived regulatory and abnormal proteins in the presence of ATP. Hydrolyzes two ATP for each peptide bond cleaved in the protein substrate. Belongs to the family S16 of the serine peptidases. The catalytic dyad consists of Ser and Lys residues. Localized in the cytoplasm.; High confidence in function and specificity; endopeptidase La 650143 lonA 10977659 lonA Zobellia galactanivorans endopeptidase La YP_004734971.1 647675 R 63186 CDS YP_004734972.1 340616519 10978100 650212..650304 1 NC_015844.1 Hypothetical protein; hypothetical protein 650304 10978100 zobellia_510 Zobellia galactanivorans hypothetical protein YP_004734972.1 650212 D 63186 CDS YP_004734973.1 340616520 10977135 650328..650912 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 650912 10977135 zobellia_511 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004734973.1 650328 D 63186 CDS YP_004734974.1 340616521 10977136 650916..651473 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 651473 10977136 zobellia_512 Zobellia galactanivorans membrane protein YP_004734974.1 650916 D 63186 CDS YP_004734975.1 340616522 10977137 651454..652545 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 652545 10977137 zobellia_513 Zobellia galactanivorans hypothetical protein YP_004734975.1 651454 D 63186 CDS YP_004734976.1 340616523 10977138 652580..653302 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; hypothetical protein 653302 10977138 zobellia_514 Zobellia galactanivorans hypothetical protein YP_004734976.1 652580 D 63186 CDS YP_004734977.1 340616524 10977139 complement(653346..654671) 1 NC_015844.1 The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients; Contains 10 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; major facilitator family transporter 654671 10977139 zobellia_515 Zobellia galactanivorans major facilitator family transporter YP_004734977.1 653346 R 63186 CDS YP_004734978.1 340616525 10977140 complement(654738..655550) 1 NC_015844.1 Metallopeptidases hydrolyze the peptidic bonds in proteins and peptides with a single catalytic zinc ion tetrahedrally co-ordinated by two histidines within an HEXXH motif, an as yet undetermined third residue as well as a water molecule. The glutamate residue within the HEXXH motif is essential for catalysis; Belongs to the M48 family of peptidases; Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Specificity unclear; metallopeptidase 655550 10977140 zobellia_516 Zobellia galactanivorans metallopeptidase YP_004734978.1 654738 R 63186 CDS YP_004734979.1 340616526 10977141 complement(655586..657985) 1 NC_015844.1 Alpha-glucosidase catalyzes the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose. It belongs to the family 31 of the glycoside hydrolases. Involved in starch or glycogen metabolism.; High confidence in function and specificity; alpha-glucosidase 657985 malA 10977141 malA Zobellia galactanivorans alpha-glucosidase YP_004734979.1 655586 R 63186 CDS YP_004734980.1 340616527 10978119 complement(658086..659987) 1 NC_015844.1 1,4-alpha-glucan branching enzyme catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Has a preference for transferring chains of 5 to 16 glucose units. Belongs to the family 13 of the glycoside hydrolases.; High confidence in function and specificity; 1,4-alpha-glucan branching protein 659987 glgB 10978119 glgB Zobellia galactanivorans 1,4-alpha-glucan branching protein YP_004734980.1 658086 R 63186 CDS YP_004734981.1 340616528 10977913 660185..660757 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 660757 10977913 zobellia_519 Zobellia galactanivorans lipoprotein YP_004734981.1 660185 D 63186 CDS YP_004734982.1 340616529 10977142 complement(660812..660910) 1 NC_015844.1 Hypothetical protein; hypothetical protein 660910 10977142 zobellia_520 Zobellia galactanivorans hypothetical protein YP_004734982.1 660812 R 63186 CDS YP_004734983.1 340616530 10977144 660929..661432 1 NC_015844.1 Peptide methionine sulphoxide reductase reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide to methionine. MsrB is specific for methionine-R-sulfoxides. It activates the cysteine or selenocysteine nucleophile through a unique Cys-Arg-Asp/Glu catalytic triad. Regeneration of the active site occurs through a series of thiol-disulfide exchange steps involving another active site Cys residue and thioredoxin. Localized in the cytoplasm.; High confidence in function and specificity; peptide methionine sulfoxide reductase msrB 661432 msrB1 10977144 msrB1 Zobellia galactanivorans peptide methionine sulfoxide reductase msrB YP_004734983.1 660929 D 63186 CDS YP_004734984.1 340616531 10978195 661488..662015 1 NC_015844.1 Conserved protein belonging to the DUF1572 family; Localized in the cytoplasm; hypothetical protein 662015 10978195 zobellia_522 Zobellia galactanivorans hypothetical protein YP_004734984.1 661488 D 63186 CDS YP_004734985.1 340616532 10977145 662180..663571 1 NC_015844.1 The Dihydrolipoyl dehydrogenase is the E3 component of the branched-chain alpha-keto dehydrogenase complex. This complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It is involved in valine, leucine and isoleucine biodegradation. It contains multiple copies of three enzymatic components: branched- chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). The E3 component converts the Protein 6-N-(dihydrolipoyl)lysine to protein 6-N-(lipoyl)lysine. Dihydrolipoyl dehydrogenase is a homodimer, which binds 1 NADP and 1 FAD per subunit; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family; Localized in the cytoplasm; High confidence in function and specificity; dihydrolipoyl dehydrogenase, E3 component 663571 bfmBC 10977145 bfmBC Zobellia galactanivorans dihydrolipoyl dehydrogenase, E3 component YP_004734985.1 662180 D 63186 CDS YP_004734986.1 340616533 10977592 663675..663965 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 663965 10977592 zobellia_524 Zobellia galactanivorans membrane protein YP_004734986.1 663675 D 63186 CDS YP_004734987.1 340616534 10977146 complement(663983..664501) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 664501 10977146 zobellia_525 Zobellia galactanivorans periplasmic protein YP_004734987.1 663983 R 63186 CDS YP_004734988.1 340616535 10977147 complement(664681..665097) 1 NC_015844.1 3-dehydroquinate dehydratase (or dehydroquinases) catalyzes the conversion of 3-dehydroquinate into 3-dehydroshikimate. It is the third step in the shikimate pathway for the biosynthesis of aromatic amino acids from chorismate. AroQ belongs to the class II of the dehydroquinases. It forms a homododecamer. Localized in the cytoplasm.; High confidence in function and specificity; 3-dehydroquinate dehydratase 665097 aroQ 10977147 aroQ Zobellia galactanivorans 3-dehydroquinate dehydratase YP_004734988.1 664681 R 63186 CDS YP_004734989.1 340616536 10977550 complement(665191..665811) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 32 and 33; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 665811 10977550 zobellia_527 Zobellia galactanivorans periplasmic protein YP_004734989.1 665191 R 63186 CDS YP_004734990.1 340616537 10977148 666023..666919 1 NC_015844.1 Tyrosine recombinase XerD acts by catalyzing the cutting and rejoining of the recombining DNA molecules utilizing a catalytic tyrosine for the strand cleavage; The cyclic heterotetrameric complex is composed of two molecules of XerC and two molecules of XerD. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids at ColE1 xer (or cer) and pSC101 (or psi) sites; Belongs to the \\phage\\ integrase family, XerD and XerC integrases subfamily; Localized in the cytoplasm; High confidence in function and specificity; tyrosine recombinase XerD 666919 xerD 10977148 xerD Zobellia galactanivorans tyrosine recombinase XerD YP_004734990.1 666023 D 63186 CDS YP_004734991.1 340616538 10978761 complement(666926..667432) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 667432 10978761 zobellia_529 Zobellia galactanivorans hypothetical protein YP_004734991.1 666926 R 63186 CDS YP_004734992.1 340616539 10977149 667655..669349 1 NC_015844.1 Oligo-1,6-glucosidase catalyzes the hydrolysis of 1, 6-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose; Belongs to the family 13 of the glycoside hydrolases; Localized in the cytoplasm; High confidence in function and specificity; Oligo-1,6-glucosidase 669349 malL 10977149 malL Zobellia galactanivorans Oligo-1,6-glucosidase YP_004734992.1 667655 D 63186 CDS YP_004734993.1 340616540 10978120 complement(669334..670659) 1 NC_015844.1 NADH dehydrogenases catalyze the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation; Binds 1 FAD noncovalently per subunit; Contains one tranmembrane segment; Belongs to the NADH dehydrogenase family; Localized in the cytoplasmic membrane; High confidence in function and specificity; NADH dehydrogenase 670659 ndhA1 10978120 ndhA1 Zobellia galactanivorans NADH dehydrogenase YP_004734993.1 669334 R 63186 CDS YP_004734994.1 340616541 10978242 670986..671480 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 671480 10978242 zobellia_532 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004734994.1 670986 D 63186 CDS YP_004734995.1 340616542 10977151 671485..672135 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 672135 10977151 zobellia_533 Zobellia galactanivorans membrane protein YP_004734995.1 671485 D 63186 CDS YP_004734996.1 340616543 10977152 complement(672132..672947) 1 NC_015844.1 Acyltransferase catalyzes of the generalized reaction: acyl-carrier + reactant = acyl-reactant + carrier. This enzyme belongs to an acyltransferase family including enzymes involved in phospholipid biosynthesis. Its exact specificity is unknown. Localized in the cytoplasm.; Specificity unclear; acyltransferase 672947 10977152 zobellia_534 Zobellia galactanivorans acyltransferase YP_004734996.1 672132 R 63186 CDS YP_004734997.1 340616545 10977153 complement(672973..673617) 1 NC_015844.1 NUDIX hydrolase belongs to a family of enzymes hydrolyzing diverse nucleoside diphosphate derivatives (including ADP-ribose, GDP- mannose, TDP-glucose, NADH, UDP-sugars, dNTP and NTP). Localized in the cytoplasm.; Function unclear; NUDIX hydrolase 673617 10977153 zobellia_536 Zobellia galactanivorans NUDIX hydrolase YP_004734997.1 672973 R 63186 CDS YP_004734998.1 340616544 10977155 673616..674329 1 NC_015844.1 Peptidyl-prolyl cis-trans isomerase, or PPIase or rotamase, accelerates the folding of proteins. It catalyzes the peptidyl-prolyl isomerisation during which the peptide bond preceding proline (the peptidyl-prolyl bond) is stabilised in the cis conformation in oligopeptides; Contains a C-terminal Cyclophilin-type peptidyl-prolyl cis-trans isomerase/CLD domain; Signal peptide of lipoprotein cleaved between the residues 19 and 20; Localized in the outer membrane; High confidence in function and specificity; cyclophilin-type peptidyl-prolyl cis-trans isomerase 674329 10977155 zobellia_535 Zobellia galactanivorans cyclophilin-type peptidyl-prolyl cis-trans isomerase YP_004734998.1 673616 D 63186 CDS YP_004734999.1 340616546 10977154 complement(674343..674960) 1 NC_015844.1 Conserved membrane protein containing two UPF0126 domains. The conserved glycines are suggestive of an ion channel. Contains seven transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 674960 10977154 zobellia_537 Zobellia galactanivorans membrane protein YP_004734999.1 674343 R 63186 CDS YP_004735000.1 340616547 10977156 complement(675021..675737) 1 NC_015844.1 This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. Contains three transmembrane helices. The arginine occurs at the N terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this protein is unknown; Localized in the cytoplasmic membrane; Family membership; RDD family membrane protein 675737 10977156 zobellia_538 Zobellia galactanivorans RDD family membrane protein YP_004735000.1 675021 R 63186 CDS YP_004735001.1 340616548 10977157 675770..676729 1 NC_015844.1 Conserved integral membrane protein belonging to the DUF95 family. Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 676729 10977157 zobellia_539 Zobellia galactanivorans membrane protein YP_004735001.1 675770 D 63186 CDS YP_004735002.1 340616549 10977158 676726..677598 1 NC_015844.1 Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 677598 10977158 zobellia_540 Zobellia galactanivorans membrane protein YP_004735002.1 676726 D 63186 CDS YP_004735003.1 340616550 10977160 677601..678341 1 NC_015844.1 Contains one central transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 678341 10977160 zobellia_541 Zobellia galactanivorans membrane protein YP_004735003.1 677601 D 63186 CDS YP_004735004.1 340616551 10977161 678334..679557 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 679557 10977161 zobellia_542 Zobellia galactanivorans membrane protein YP_004735004.1 678334 D 63186 CDS YP_004735005.1 340616552 10977162 679535..680533 1 NC_015844.1 ATPase belonging to the MoxR-like family. In Paracoccus denitrificans, MoxR is involved in the regulation of formation of active methanol dehydrogenase. MoxR-like ATPases have been proposed to function with VWA domain proteins to form a chaperone system involved in the activation of proteins by primarily mediating the insertion of metal cofactors into the substrate molecules; Localized in the cytoplasm; Specificity unclear; MoxR-like ATPase 680533 10977162 zobellia_543 Zobellia galactanivorans MoxR-like ATPase YP_004735005.1 679535 D 63186 CDS YP_004735006.1 340616553 10977163 680536..681867 1 NC_015844.1 Conserved protein belonging to the von Willebrand factor type A (vWA) domain family. Some VWA domain proteins have been proposed to function with MoxR-like ATPases to form a chaperone system involved in the activation of proteins by primarily mediating the insertion of metal cofactors into the substrate molecules. Contains two N-terminal transmembrane helices; Localized in the cytoplasmic membrane; Function unclear; vWA domain-containing protein 681867 10977163 zobellia_544 Zobellia galactanivorans vWA domain-containing protein YP_004735006.1 680536 D 63186 CDS YP_004735007.1 340616554 10977164 681946..682155 1 NC_015844.1 Hypothetical protein; hypothetical protein 682155 10977164 zobellia_545 Zobellia galactanivorans hypothetical protein YP_004735007.1 681946 D 63186 CDS YP_004735008.1 340616555 10977165 682163..682696 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 682696 10977165 zobellia_546 Zobellia galactanivorans hypothetical protein YP_004735008.1 682163 D 63186 CDS YP_004735009.1 340616556 10977166 682841..683860 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 683860 10977166 zobellia_547 Zobellia galactanivorans periplasmic protein YP_004735009.1 682841 D 63186 CDS YP_004735010.1 340616557 10977167 683886..684401 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 684401 10977167 zobellia_548 Zobellia galactanivorans hypothetical protein YP_004735010.1 683886 D 63186 CDS YP_004735011.1 340616558 10977168 684504..684728 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 684728 10977168 zobellia_549 Zobellia galactanivorans hypothetical protein YP_004735011.1 684504 D 63186 CDS YP_004735012.1 340616559 10977169 684807..688217 1 NC_015844.1 Protein containing a N-terminal beta-propeller fold domain, three central PBS lyase HEAT-like repeats and a C-terminal cytochrome c domain. Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the outer membrane; Function unclear; cytochrome c-containing protein 688217 10977169 zobellia_550 Zobellia galactanivorans cytochrome c-containing protein YP_004735012.1 684807 D 63186 CDS YP_004735013.1 340616560 10977171 complement(688287..689228) 1 NC_015844.1 2-Nitropropane dioxygenase catalyzes the oxidation of nitroalkanes to produce the corresponding carbonyl compounds. It acts on 2-nitropropane better than on nitroethane and 1-nitropropane, and anionic forms of nitroalkanes are much better substrates than are neutral forms. It forms a homodimer and uses FMN as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; 2-nitropropane dioxygenase 689228 ncd1 10977171 ncd1 Zobellia galactanivorans 2-nitropropane dioxygenase YP_004735013.1 688287 R 63186 CDS YP_004735014.1 340616561 10978240 complement(689253..690512) 1 NC_015844.1 TrmU modified the wobble bases of bacterial tRNAs responsible for NNR codons to 5-methylaminomethyl-2-thiouridine (mnm5s2U). 2-thio modification of mnm5s2U is required for accurate decoding and essential for normal cell growth. It uses S-adenosyl-L-methionine as cofactor. Interacts with tusE. Localized in the cytoplasm.; High confidence in function and specificity; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 690512 trmU 10978240 trmU Zobellia galactanivorans tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_004735014.1 689253 R 63186 CDS YP_004735015.1 340616562 10978691 690672..692042 1 NC_015844.1 Conserved protein containing three fascilin domains. These domains, also known as FAS1 or BIgH3 domains, are extracellular modules of about 140 amino acid residues. In Eukaryotes, they mediate cell adhesion throught an interaction with alpha3/beta1 integrin. Each fascilin domain consists of seven-stranded wedge and at least five alpha helices. Features a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Family membership; fasciclin repeat-containing protein 692042 10978691 zobellia_553 Zobellia galactanivorans fasciclin repeat-containing protein YP_004735015.1 690672 D 63186 CDS YP_004735016.1 340616563 10977172 complement(692406..694256) 1 NC_015844.1 OxaA is an inner membrane protein required for the insertion of integral membrane proteins into the membrane. It is a component of the SecDFyajC complex, a heterotetrameric translocase complex, interacting with secD and secF. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration. Features six transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; inner membrane protein oxaA 694256 oxaA 10977172 oxaA Zobellia galactanivorans inner membrane protein oxaA YP_004735016.1 692406 R 63186 CDS YP_004735017.1 340616564 10978290 complement(694385..696001) 1 NC_015844.1 CTP synthase is involved in pyrimidine nucleotide biosynthesis. It catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. It forms a homotetramer. Localized in the cytoplasm.; High confidence in function and specificity; CTP synthase 696001 pyrG 10978290 pyrG Zobellia galactanivorans CTP synthase YP_004735017.1 694385 R 63186 CDS YP_004735018.1 340616565 10978422 complement(696060..696299) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 696299 10978422 zobellia_556 Zobellia galactanivorans hypothetical protein YP_004735018.1 696060 R 63186 CDS YP_004735019.1 340616566 10977173 696343..697212 1 NC_015844.1 Belongs to the xylose isomerase-like TIM barrel family. Exported by the twin-arginine translocation pathway signal.; Specificity unclear; xylose isomerase-like TIM barrel protein 697212 10977173 zobellia_557 Zobellia galactanivorans xylose isomerase-like TIM barrel protein YP_004735019.1 696343 D 63186 CDS YP_004735020.1 340616567 10977174 complement(697247..697993) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, that acts as transcriptional regulator; Family membership; two-component system-response regulator 697993 10977174 zobellia_558 Zobellia galactanivorans two-component system-response regulator YP_004735020.1 697247 R 63186 CDS YP_004735021.1 340616568 10977175 complement(698001..700079) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Signal peptide cleaved between the residues 22 and 23; Contains seven tetratrico peptide repeats (TPR) and one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 700079 10977175 zobellia_559 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004735021.1 698001 R 63186 CDS YP_004735022.1 340616569 10977176 complement(700133..700294) 1 NC_015844.1 Contains one transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 700294 10977176 zobellia_560 Zobellia galactanivorans membrane protein YP_004735022.1 700133 R 63186 CDS YP_004735023.1 340616570 10977177 700324..700983 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 700983 10977177 zobellia_561 Zobellia galactanivorans hypothetical protein YP_004735023.1 700324 D 63186 CDS YP_004735024.1 340616571 10977178 701020..701304 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Hypothetical protein; hypothetical protein 701304 10977178 zobellia_562 Zobellia galactanivorans hypothetical protein YP_004735024.1 701020 D 63186 CDS YP_004735025.1 340616572 10977179 701346..701900 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Hypothetical protein; hypothetical protein 701900 10977179 zobellia_563 Zobellia galactanivorans hypothetical protein YP_004735025.1 701346 D 63186 CDS YP_004735026.1 340616573 10977180 702085..702615 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 702615 10977180 zobellia_564 Zobellia galactanivorans hypothetical protein YP_004735026.1 702085 D 63186 CDS YP_004735027.1 340616574 10977181 complement(702652..703149) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 703149 10977181 zobellia_565 Zobellia galactanivorans hypothetical protein YP_004735027.1 702652 R 63186 CDS YP_004735028.1 340616575 10977182 complement(703188..703592) 1 NC_015844.1 This protein belongs to a family including OsmC, the osmotically inducible protein C; localized in the cytoplasm; Family membership; OsmC family protein 703592 10977182 zobellia_566 Zobellia galactanivorans OsmC family protein YP_004735028.1 703188 R 63186 CDS YP_004735029.1 340616576 10977183 complement(703687..705855) 1 NC_015844.1 Conserved protein containing five N-terminal LysM repeats and a C-terminal domain of unknown function. The LysM (lysin motif) domain is about 40 residues long and belongs to the family 50 of the carbohydrate binding modules (CBM50). It is found in a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. Features a signal peptide cleaved between the residues 23 and 24. Localized in the periplasm.; Function unclear; CBM50-containing protein 705855 10977183 zobellia_567 Zobellia galactanivorans CBM50-containing protein YP_004735029.1 703687 R 63186 CDS YP_004735030.1 340616577 10977184 complement(705858..707390) 1 NC_015844.1 The GMP synthase is a glutamine amidotransferase from the de novo purine biosynthetic pathway. It catalyzes the synthesis of guanosine 5'monophosphate (GMP) from xanthosine 5'monophosphate (XMP), ATP and glutamine; Belongs to the Glutamine amidotransferase, class I family defined by a conserved catalytic triad consisting of cysteine, histidine and glutamate; Localized in the cytoplasm; High confidence in function and specificity; GMP synthase 707390 guaA 10977184 guaA Zobellia galactanivorans GMP synthase YP_004735030.1 705858 R 63186 CDS YP_004735031.1 340616578 10977954 707433..707678 1 NC_015844.1 Hypothetical protein; hypothetical protein 707678 10977954 zobellia_569 Zobellia galactanivorans hypothetical protein YP_004735031.1 707433 D 63186 CDS YP_004735032.1 340616579 10977185 707988..710459 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (57-134) and the Plug module (152-258) acting as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 710459 10977185 zobellia_570 Zobellia galactanivorans TonB-dependent Receptor YP_004735032.1 707988 D 63186 CDS YP_004735033.1 340616580 10977186 710463..710918 1 NC_015844.1 Contains a lipoprotein signal peptide cleaved between the residues 17 and 18; Probably localized in the outer membrane; Hypothetical protein; hypothetical protein 710918 10977186 zobellia_571 Zobellia galactanivorans hypothetical protein YP_004735033.1 710463 D 63186 CDS YP_004735034.1 340616581 10977187 711037..711351 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 711351 10977187 zobellia_572 Zobellia galactanivorans hypothetical protein YP_004735034.1 711037 D 63186 CDS YP_004735035.1 340616582 10977188 711534..712076 1 NC_015844.1 Pyridoxamine 5'-phosphate oxidase is involved in the vitamine B6 metabolism. It oxidizes pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). It forms a homodimer and binds one FMN as cofactor per subunit. Localized in the cytoplasm.; High confidence in function and specificity; pyridoxamine 5'-phosphate oxidase 712076 pdxH2 10977188 pdxH2 Zobellia galactanivorans pyridoxamine 5'-phosphate oxidase YP_004735035.1 711534 D 63186 CDS YP_004735036.1 340616583 10978321 complement(712088..713689) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 713689 10978321 zobellia_574 Zobellia galactanivorans hypothetical protein YP_004735036.1 712088 R 63186 CDS YP_004735037.1 340616584 10977189 713840..716305 1 NC_015844.1 Peptidase family M14 contains mainly metallocarboxypeptidases. The single catalytic zinc ion is tetrahedrally coordinated by two histidines and a glutamate, as well as a water molecule. One of the histidines and the glutamate occur in the motif His-Xaa-Xaa-Glu; Signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Specificity unclear; metallopeptidase 4 716305 10977189 zobellia_575 Zobellia galactanivorans metallopeptidase 4 YP_004735037.1 713840 D 63186 CDS YP_004735038.1 340616585 10977190 716344..717390 1 NC_015844.1 Conserved protein belonging to the zinc-dependent beta-lactamase superfamily. This superfamily contains various metallo-hydrolases including beta-lactamases, but also glyoxylases and arylsulfatases. The active site is characterized by several conserved histidines binding the catalytic zinc ions. The enzymes can bind one or two zinc ions. Localized in the cytoplasm; Family membership; metallo-beta-lactamase superfamily protein 717390 10977190 zobellia_576 Zobellia galactanivorans metallo-beta-lactamase superfamily protein YP_004735038.1 716344 D 63186 CDS YP_004735039.1 340616586 10977191 complement(717425..718030) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 718030 10977191 zobellia_577 Zobellia galactanivorans membrane protein YP_004735039.1 717425 R 63186 CDS YP_004735040.1 340616587 10977192 718241..718750 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 718750 10977192 zobellia_578 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004735040.1 718241 D 63186 CDS YP_004735041.1 340616588 10977193 718912..719844 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 719844 10977193 zobellia_579 Zobellia galactanivorans hypothetical protein YP_004735041.1 718912 D 63186 CDS YP_004735042.1 340616589 10977194 719943..720272 1 NC_015844.1 Arsr is the transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of arsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)). Contains 1 HTH arsR-type DNA-binding domain. Localized in the cytoplasm.; High confidence in function and specificity; Arsenical resistance operon repressor 720272 arsR 10977194 arsR Zobellia galactanivorans Arsenical resistance operon repressor YP_004735042.1 719943 D 63186 CDS YP_004735043.1 340616590 10977554 720323..720790 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 720790 10977554 zobellia_581 Zobellia galactanivorans hypothetical protein YP_004735043.1 720323 D 63186 CDS YP_004735044.1 340616591 10977195 720826..721452 1 NC_015844.1 Protein arsC reduces arsenate [As(V)] to arsenite [As(III)] (Arsenate reductase, EC 1.20.4.-) and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates (LMW protein-tyrosine-phosphatase, EC 3.1.3.48). Could switch between different functions in different circumstances. Localized in the cytoplasm.; High confidence in function and specificity; protein arsC 721452 arsC 10977195 arsC Zobellia galactanivorans protein arsC YP_004735044.1 720826 D 63186 CDS YP_004735045.1 340616592 10977553 721445..722497 1 NC_015844.1 Arsenite resistance protein ArsB seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump. Belongs to the Sodium Bile acid symporter family; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; Arsenite resistance protein 722497 arsB 10977553 arsB Zobellia galactanivorans Arsenite resistance protein YP_004735045.1 721445 D 63186 CDS YP_004735046.1 340616593 10977551 722684..724144 1 NC_015844.1 Cell volume regulation protein A participates in control of cell volume in low-osmolarity conditions. It belongs to the Na/H antiporters. This integral membrane protein also features a C-terminal TrkA-C domain which may bind an unidentified ligand and is predicted to adopt an all beta structure. Features eleven transmembrane helices.; High confidence in function and specificity; cell volume regulation protein A 724144 cvrA 10977551 cvrA Zobellia galactanivorans cell volume regulation protein A YP_004735046.1 722684 D 63186 CDS YP_004735047.1 340616594 10977694 724189..724554 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Hypothetical protein; hypothetical protein 724554 10977694 zobellia_585 Zobellia galactanivorans hypothetical protein YP_004735047.1 724189 D 63186 CDS YP_004735048.1 340616595 10977196 724657..725142 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 725142 10977196 zobellia_586 Zobellia galactanivorans membrane protein YP_004735048.1 724657 D 63186 CDS YP_004735049.1 340616596 10977197 complement(725213..726211) 1 NC_015844.1 Gluconolactonases hydrolyze the gluconolactone formed by glucose oxidoreductase. The proximity of the galactonate dehydratase gene dgoD suggests that this lactonase would be specific for D-galactono-1,4-lactone instead of gluconolactone; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasm.; Specificity unclear; gluconolactonase 726211 10977197 zobellia_587 Zobellia galactanivorans gluconolactonase YP_004735049.1 725213 R 63186 CDS YP_004735050.1 340616597 10977198 complement(726247..727569) 1 NC_015844.1 GntT is part of the gluconate utilization system Gnt-I. It is a permease responsible for high-affinity intake of gluconate; Contains 13 transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; high-affinity gluconate transporter 727569 gntT1 10977198 gntT1 Zobellia galactanivorans high-affinity gluconate transporter YP_004735050.1 726247 R 63186 CDS YP_004735051.1 340616598 10977943 complement(727641..728798) 1 NC_015844.1 Galactonate dehydratase, involved in the galactose metabolism, converts the D-galactonate to 2-dehydro-3-deoxy-D-galactonate ; These enzymes feature a N-terminal domain with a Enolase N-terminal domain-like fold and a C-terminal TIM alpha/beta barrel fold; Belongs to the Mandelate racemase/muconate lactonizing enzyme family; Localized in the cytoplas; High confidence in function and specificity; galactonate dehydratase 728798 dgoD 10977943 dgoD Zobellia galactanivorans galactonate dehydratase YP_004735051.1 727641 R 63186 CDS YP_004735052.1 340616599 10977739 complement(729010..730311) 1 NC_015844.1 Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership; MiaB-like tRNA modifying protein 730311 10977739 zobellia_590 Zobellia galactanivorans MiaB-like tRNA modifying protein YP_004735052.1 729010 R 63186 CDS YP_004735053.1 340616600 10977199 730432..731532 1 NC_015844.1 Serine peptidase which includes D-Ala-D-Ala carboxypeptidase B and aminopeptidase DmpB. The active site residues Ser and Lys form the catalytic dyad and are found in the motif Ser-Xaa-Thr-Lys; Belongs to the family S12 of peptidases; Contains a prokaryotic lipoprotein signal peptide (cleavage between 18 and 19; Localized in the outer membrane; Specificity unclear; serine peptidase 731532 10977199 zobellia_591 Zobellia galactanivorans serine peptidase YP_004735053.1 730432 D 63186 CDS YP_004735054.1 340616601 10977200 complement(731522..732478) 1 NC_015844.1 The cell division protein FtsY is a functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger factor binding to the ribosome. Subcellular localization studies revealed that FtsY is located in part at the cytoplasmic membrane with which it seems peripherally associated.; High confidence in function and specificity; cell division protein FtsY 732478 ftsY 10977200 ftsY Zobellia galactanivorans cell division protein FtsY YP_004735054.1 731522 R 63186 CDS YP_004735055.1 340616602 10977854 complement(732659..732811) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 732811 10977854 zobellia_593 Zobellia galactanivorans hypothetical protein YP_004735055.1 732659 R 63186 CDS YP_004735056.1 340616603 10977201 complement(732848..733030) 1 NC_015844.1 Ribosomal protein L33 is one of the proteins from the large ribosomal subunit (50S); L33 has been shown to be on the surface of 50S subunit; Belongs to the ribosomal protein L33p family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L33 733030 rpmG 10977201 rpmG Zobellia galactanivorans 50S ribosomal protein L33 YP_004735056.1 732848 R 63186 CDS YP_004735057.1 340616604 10978522 complement(733042..733278) 1 NC_015844.1 Ribosomal protein L28 is a part of the large subunit (50S) of the ribosome; RpmB interacts with the proteins RplQ (L17) and RpmF (L32); Belongs to the ribosomal protein L28p family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L28 733278 rpmB 10978522 rpmB Zobellia galactanivorans 50S ribosomal protein L28 YP_004735057.1 733042 R 63186 CDS YP_004735058.1 340616605 10978517 complement(733346..734596) 1 NC_015844.1 Conserved protein belonging to the CinA family. Contains a N-terminal molybdopterin binding domain and a C-terminal Competence-damaged domain . CinA is the first gene in the competence-inducible (cin) operon, and is thought to be specifically required at some stage in the process of transformation. Localized in the cytoplasm.; Function unclear; CinA-like protein 734596 cinA 10978517 cinA Zobellia galactanivorans CinA-like protein YP_004735058.1 733346 R 63186 CDS YP_004735059.1 340616606 10977649 complement(734596..734934) 1 NC_015844.1 The histidine-containing phosphotransfer (HPt) domain is a novel protein module with an active histidine residue that mediates phosphotransfer reactions in the two-component signaling systems. The domain consists of six alpha helices containing a four-helix bundle-folding. Localized in the cytoplasm.; Family membership; Hpt domain-containing protein 734934 10977649 zobellia_597 Zobellia galactanivorans Hpt domain-containing protein YP_004735059.1 734596 R 63186 CDS YP_004735060.1 340616607 10977202 complement(734934..735545) 1 NC_015844.1 Conserved protein belonging to the Fumarylacetoacetate hydrolase family, but its exact function is not known. Fumarylacetoacetate hydrolase is the last enzyme of the tyrosine catabolic pathway. Localized in the cytoplasm.; Family membership; fumarylacetoacetate hydrolase family protein 735545 10977202 zobellia_598 Zobellia galactanivorans fumarylacetoacetate hydrolase family protein YP_004735060.1 734934 R 63186 CDS YP_004735061.1 340616608 10977203 complement(735563..736339) 1 NC_015844.1 This Exonuclease probably exhibits a 3' to 5' deoxyribonuclease activity or a ribonuclease activity; Contains an exonuclease domain; Localized in the cytoplasm; Family membership; exonuclease 736339 10977203 zobellia_599 Zobellia galactanivorans exonuclease YP_004735061.1 735563 R 63186 CDS YP_004735062.1 340616609 10977204 complement(736633..737985) 1 NC_015844.1 The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It is involved in valine, leucine and isoleucine biodegradation. It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). This protein is the E2 component and catalyzes the reaction: 2-methylpropanoyl-CoA + enzyme 6-N-(dihydrolipoyl)lysine = CoA + enzyme 6-N-(S-(2-methylpropanoyl)dihydrolipoyl)lysine. It features one N-terminal lipoyl-binding domain, a central E3-binding domain, and a C-terminal catalytic domain belonging to the 2-oxoacid dehydrogenases acyltransferase family. The lipoyl-binding domain has a conserved lysine residue that covalently binds lipoic acid. This protein forms a 24-polypeptide structural core with octahedral symmetry. Localized in the cytoplasm.; High confidence in function and specificity; dihydrolipoyllysine-residue (2-methylpropanoyl) transferase, E2 component 737985 bfmBAB 10977204 bfmBAB Zobellia galactanivorans dihydrolipoyllysine-residue (2-methylpropanoyl) transferase, E2 component YP_004735062.1 736633 R 63186 CDS YP_004735063.1 340616610 10977591 complement(738068..738688) 1 NC_015844.1 Recombination protein RecR may play a role in DNA repair. It seems to be involved in an recBC-independent recombinational process of DNA repair. It may act with recF and recO. It contains a putative C4-type zinc finger in the N-terminal section; Localized in the cytoplasm; High confidence in function and specificity; Recombination protein RecR 738688 recR 10977591 recR Zobellia galactanivorans Recombination protein RecR YP_004735063.1 738068 R 63186 CDS YP_004735064.1 340616611 10978449 738746..740224 1 NC_015844.1 Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains 13 transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sodium/solute symporter 740224 10978449 zobellia_602 Zobellia galactanivorans sodium/solute symporter YP_004735064.1 738746 D 63186 CDS YP_004735065.1 340616612 10977207 complement(740287..740646) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 740646 10977207 zobellia_603 Zobellia galactanivorans hypothetical protein YP_004735065.1 740287 R 63186 CDS YP_004735066.1 340616613 10977208 complement(740867..741874) 1 NC_015844.1 3-oxoacyl-[acyl-carrier-protein] synthase III, also known as beta-ketoacyl-ACP synthase III, catalyses the reaction: Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = 3-oxoacyl-[acyl-carrier-protein] + CO2 + [acyl-carrier-protein]. This is the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for acetyl-CoA. Its substrate specificity determines the biosynthesis of straight-chain of fatty acids instead of branched-chain. Negatively regulated by acyl-ACP, possibly by binding to either the free enzyme or the acyl-enzyme intermediate; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP synthase III 741874 fabH1 10977208 fabH1 Zobellia galactanivorans 3-oxoacyl-ACP synthase III YP_004735066.1 740867 R 63186 CDS YP_004735067.1 340616614 10977805 complement(741983..743293) 1 NC_015844.1 Conserved protein belonging to the protein kinase superfamily; Localized in the cytoplasm; Family membership; protein kinase superfamily protein 743293 10977805 zobellia_605 Zobellia galactanivorans protein kinase superfamily protein YP_004735067.1 741983 R 63186 CDS YP_004735068.1 340616615 10977209 complement(743330..743986) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 743986 10977209 zobellia_606 Zobellia galactanivorans hypothetical protein YP_004735068.1 743330 R 63186 CDS YP_004735069.1 340616616 10977210 744425..746314 1 NC_015844.1 The heat shock protein HtpG is a molecular chaperone. Has ATPase activity. It forms a homodimer; Belongs to the HSP90 family; Localized in the cytoplasm; High confidence in function and specificity; chaperone protein htpG 746314 htpG 10977210 htpG Zobellia galactanivorans chaperone protein htpG YP_004735069.1 744425 D 63186 CDS YP_004735070.1 340616618 10978001 complement(746386..746529) 1 NC_015844.1 Hypothetical protein; hypothetical protein 746529 10978001 zobellia_609 Zobellia galactanivorans hypothetical protein YP_004735070.1 746386 R 63186 CDS YP_004735071.1 340616617 10977212 746509..746724 1 NC_015844.1 Hypothetical protein; hypothetical protein 746724 10977212 zobellia_608 Zobellia galactanivorans hypothetical protein YP_004735071.1 746509 D 63186 CDS YP_004735072.1 340616619 10977211 746850..747224 1 NC_015844.1 This conserved protein adopts a beta barrel fold of the Cupin superfamily. Localized in the cytoplasm.; Conserved hypothetical protein; cupin family protein 747224 10977211 zobellia_610 Zobellia galactanivorans cupin family protein YP_004735072.1 746850 D 63186 CDS YP_004735073.1 340616620 10977213 complement(747279..748088) 1 NC_015844.1 Myo-inositol oxygenase is a non-heme iron enzyme, which catalyzes the conversion of myo-inositol to D-glucuronic acid . This enzyme can be either involved of in myo-inositol catabolism or in UDP-glucuronic acid biosynthesis. Localized in cytoplasm.; High confidence in function and specificity; Myo-inositol oxygenase 748088 mioX 10977213 mioX Zobellia galactanivorans Myo-inositol oxygenase YP_004735073.1 747279 R 63186 CDS YP_004735074.1 340616621 10978161 complement(748149..749747) 1 NC_015844.1 Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains fourteen transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sodium/solute symporter 749747 10978161 zobellia_612 Zobellia galactanivorans sodium/solute symporter YP_004735074.1 748149 R 63186 CDS YP_004735075.1 340616622 10977214 749952..750593 1 NC_015844.1 This protein belongs to the MOSC (MOCO sulfurase C-terminal) family which encompasses beta-strand-rich domains identified in the molybdenum cofactor sulfurase. These MOSC domains contain an absolutely conserved cysteine and are predicted to be sulfur-carrier domains that receive sulfur abstracted by the pyridoxal phosphate- dependent NifS-like enzymes, on their conserved cysteine, and deliver it for the formation of diverse sulfur-metal clusters. Localized in the cytoplasm.; Family membership; MOSC family protein 750593 10977214 zobellia_613 Zobellia galactanivorans MOSC family protein YP_004735075.1 749952 D 63186 CDS YP_004735076.1 340616623 10977215 750683..750943 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 750943 10977215 zobellia_614 Zobellia galactanivorans membrane protein YP_004735076.1 750683 D 63186 CDS YP_004735077.1 340616624 10977216 complement(751012..751596) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 751596 10977216 zobellia_615 Zobellia galactanivorans periplasmic protein YP_004735077.1 751012 R 63186 CDS YP_004735078.1 340616625 10977217 751838..752707 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 752707 10977217 zobellia_616 Zobellia galactanivorans AraC family transcriptional regulator YP_004735078.1 751838 D 63186 CDS YP_004735079.1 340616626 10977218 752707..753306 1 NC_015844.1 Alpha-ketoglutarate-dependent dioxygenase repairs alkylated DNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Has a strong preference for single-stranded DNA. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Localized in the cytoplasm.; High confidence in function and specificity; alpha-ketoglutarate-dependent dioxygenase 753306 alkB1 10977218 alkB1 Zobellia galactanivorans alpha-ketoglutarate-dependent dioxygenase YP_004735079.1 752707 D 63186 CDS YP_004735080.1 340616627 10977505 complement(753493..754263) 1 NC_015844.1 Nuclease S1 hydrolyzes only single stranded DNA and RNA without apparent specificity for bases; Binds 3 zinc ions as cofactors; Localized in the cytoplasm; High confidence in function and specificity; nuclease S1 754263 nucS 10977505 nucS Zobellia galactanivorans nuclease S1 YP_004735080.1 753493 R 63186 CDS YP_004735081.1 340616628 10978278 754368..756617 1 NC_015844.1 Penicillin-binding protein 1B is a class A PBP involved in the synthesis of cross-linked peptidoglycan from the lipid II intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). The N-terminal domain belongs to the family 51 of the glycosyltransferases. Features an uncleaved signal peptide. Localized in the periplasm, anchored to the cytoplasmic membrane.; High confidence in function and specificity; penicillin-binding protein 1B, family GT51 756617 pbp1B 10978278 pbp1B Zobellia galactanivorans penicillin-binding protein 1B, family GT51 YP_004735081.1 754368 D 63186 CDS YP_004735082.1 340616629 10978306 756645..757448 1 NC_015844.1 The hydrolases of the superfamily HAD (Haloacid dehalogenase) catalyse a nucleophilic displacement reaction, with water as the sole co-substrate. They are structurally different from the alpha/beta hydrolase family (abhydrolase); Belongs to the haloacid dehalogenase- like hydrolase superfamily, class II family, class IIB subfamily; Localized in the cytoplasm; Family membership; hydrolase HAD superfamily 757448 10978306 zobellia_620 Zobellia galactanivorans hydrolase HAD superfamily YP_004735082.1 756645 D 63186 CDS YP_004735083.1 340616630 10977219 757480..758796 1 NC_015844.1 Conserved protein belonging to the DUF819 family. Features eleven transmembrane helices; Localized in the cytoplasmic membrane; Family membership; hypothetical protein 758796 10977219 zobellia_621 Zobellia galactanivorans hypothetical protein YP_004735083.1 757480 D 63186 CDS YP_004735084.1 340616631 10977220 758849..759532 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 759532 10977220 zobellia_622 Zobellia galactanivorans hypothetical protein YP_004735084.1 758849 D 63186 CDS YP_004735085.1 340616632 10977221 complement(759536..760501) 1 NC_015844.1 Oxydoreductase NADPH dependent; Belongs to the aldo/keto reductase 2 family; Localized in the cytoplasm; Family membership; aldo/keto reductase 760501 10977221 zobellia_623 Zobellia galactanivorans aldo/keto reductase YP_004735085.1 759536 R 63186 CDS YP_004735086.1 340616633 10977222 complement(760512..762080) 1 NC_015844.1 Conserved protein belonging to the UPF0061 family; Localized in the cytoplasm; Family membership; hypothetical protein 762080 10977222 zobellia_624 Zobellia galactanivorans hypothetical protein YP_004735086.1 760512 R 63186 CDS YP_004735087.1 340616634 10977223 complement(762128..762802) 1 NC_015844.1 Ribose-5-phosphate isomerase is involved in pentose phosphate pathway. It catalyzes the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate. Localized in the cytoplasm.; High confidence in function and specificity; ribose-5-phosphate isomerase A 762802 rpiA 10977223 rpiA Zobellia galactanivorans ribose-5-phosphate isomerase A YP_004735087.1 762128 R 63186 CDS YP_004735088.1 340616635 10978491 763010..763711 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the cytoplasmic and/or outer membrane; Conserved hypothetical protein; lipoprotein 763711 10978491 zobellia_626 Zobellia galactanivorans lipoprotein YP_004735088.1 763010 D 63186 CDS YP_004735089.1 340616636 10977224 complement(763756..764025) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 764025 10977224 zobellia_627 Zobellia galactanivorans hypothetical protein YP_004735089.1 763756 R 63186 CDS YP_004735090.1 340616637 10977225 complement(764108..765070) 1 NC_015844.1 Mannose-6-phosphate isomerase or phosphomannose isomerase (PMI) is the enzyme that converts the mannose-6-phosphate to fructose-6-phosphate. Contains a phosphomannose isomerase type I domain; Binds 1 zinc ion per subunit; Belongs to the the cupin superfamily, mannose-6-phosphate isomerase type 1 family; Localized in the cytoplasm; High confidence in function and specificity; mannose-6-phosphate isomerase, type I 765070 pmiA 10977225 pmiA Zobellia galactanivorans mannose-6-phosphate isomerase, type I YP_004735090.1 764108 R 63186 CDS YP_004735091.1 340616638 10978355 complement(765103..765510) 1 NC_015844.1 6-Pyruvoyl tetrahydrobiopterin synthase is involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. It catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. It forms a homohexamer formed of two homotrimers in a head to head fashion. Localized in the cytoplasm.; High confidence in function and specificity; 6-Pyruvoyl tetrahydrobiopterin synthase 765510 pts 10978355 pts Zobellia galactanivorans 6-Pyruvoyl tetrahydrobiopterin synthase YP_004735091.1 765103 R 63186 CDS YP_004735092.1 340616639 10978399 complement(765494..766213) 1 NC_015844.1 Isopentenyl-diphosphate Delta-isomerase is involved in isoprenoid biosynthesis. It catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl to its highly electrophilic allylic isomer, dimethylallyl diphosphate. Binds one magnesium as a cofactor when the substrate is also bound. Localized in the cytoplasm.; High confidence in function and specificity; isopentenyl-diphosphate Delta-isomerase 766213 idiA 10978399 idiA Zobellia galactanivorans isopentenyl-diphosphate Delta-isomerase YP_004735092.1 765494 R 63186 CDS YP_004735093.1 340616640 10978019 complement(766228..772563) 1 NC_015844.1 The presence of two EF-hand calcium-binding domains, four putatif thrombospondin type 3 repeats and one calx-beta motif suggest that this sequence is a calcium binding protein. The calx-beta motif is present in the cytoplasmic domains of Calx Na-Ca exchangers; Contains a Galactose-binding domain; Signal peptide cleaved between the residues 34 and 35; Putatively localized in the outer membrane; Conserved hypothetical protein; thrombospondin type 3 repeat-containing protein 772563 10978019 zobellia_631 Zobellia galactanivorans thrombospondin type 3 repeat-containing protein YP_004735093.1 766228 R 63186 CDS YP_004735094.1 340616641 10977227 complement(772625..773575) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; hypothetical protein 773575 10977227 zobellia_632 Zobellia galactanivorans hypothetical protein YP_004735094.1 772625 R 63186 CDS YP_004735095.1 340616642 10977228 complement(773584..775572) 1 NC_015844.1 Conserved protein containing five thrombospondin type 3 repeats (TSP3). TSP3 are calcium binding domains; Features an uncleaved signal peptide; Localized in the cytoplasmic meembrane; Conserved hypothetical protein; thrombospondin type 3 repeat-containing protein 775572 10977228 zobellia_633 Zobellia galactanivorans thrombospondin type 3 repeat-containing protein YP_004735095.1 773584 R 63186 CDS YP_004735096.1 340616643 10977229 complement(775633..783720) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; hypothetical protein 783720 10977229 zobellia_634 Zobellia galactanivorans hypothetical protein YP_004735096.1 775633 R 63186 CDS YP_004735097.1 340616644 10977230 complement(784125..784238) 1 NC_015844.1 Hypothetical protein; hypothetical protein 784238 10977230 zobellia_635 Zobellia galactanivorans hypothetical protein YP_004735097.1 784125 R 63186 CDS YP_004735098.1 340616645 10977231 complement(784287..788786) 1 NC_015844.1 Conserved protein containing two N-terminal Calx-beta motifs separated by a CUB domain and followed by a C-terminal beta helix fold domain of unknown function. Calx-beta motifs are involved in calcium-binding. CUB domains contain four conserved cysteines which probably form two disulfide bridges. The structure of the CUB domain has been predicted to be a β-barrel; Conserved hypothetical protein; beta helix fold protein 788786 10977231 zobellia_636 Zobellia galactanivorans beta helix fold protein YP_004735098.1 784287 R 63186 CDS YP_004735099.1 340616646 10977232 788947..789039 1 NC_015844.1 Hypothetical protein; hypothetical protein 789039 10977232 zobellia_637 Zobellia galactanivorans hypothetical protein YP_004735099.1 788947 D 63186 CDS YP_004735100.1 340616647 10977233 complement(789071..791011) 1 NC_015844.1 This protein has a modular architecture with two N-terminal TPR repeats, a central beta-propeller domain, encompassing five WD40 repeats, and a C-terminal OmpA domain. OmpA-like domain is thought to be responsible for non-covalent interactions with peptidoglycan. The tetratrico peptide repeat (TPR) is a structural motif, which mediates proteinprotein interactions. Signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Function unclear; OmpA-like outer membrane protein 791011 10977233 zobellia_638 Zobellia galactanivorans OmpA-like outer membrane protein YP_004735100.1 789071 R 63186 CDS YP_004735101.1 340616648 10977234 complement(791024..791983) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; hypothetical protein 791983 10977234 zobellia_639 Zobellia galactanivorans hypothetical protein YP_004735101.1 791024 R 63186 CDS YP_004735102.1 340616649 10977235 complement(791998..795777) 1 NC_015844.1 Proteins that probably binds the calcium ions; Contains fifteen type-3 thrombospondin repeats; signal peptide cleaved between the residues 33 and 34; probably localized in the outer membrane; Hypothetical protein; hypothetical protein 795777 10977235 zobellia_640 Zobellia galactanivorans hypothetical protein YP_004735102.1 791998 R 63186 CDS YP_004735103.1 340616650 10977237 796177..797766 1 NC_015844.1 The release factor 3 (RF-3), a class II RF, is a translation termination factor that increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP; Localized in the cytoplasm; High confidence in function and specificity; peptide chain release factor RF-3 797766 prfC 10977237 prfC Zobellia galactanivorans peptide chain release factor RF-3 YP_004735103.1 796177 D 63186 CDS YP_004735104.1 340616651 10978380 complement(797824..798135) 1 NC_015844.1 Protein localized in the cytoplasm; hypothetical protein 798135 10978380 zobellia_642 Zobellia galactanivorans hypothetical protein YP_004735104.1 797824 R 63186 CDS YP_004735105.1 340616652 10977238 complement(798189..802487) 1 NC_015844.1 The beta subunit of RNA polymerase, in association with the beta and omega subunits and the two alpha subunits, forms the polymerase core. Within the polymerase core, the beta subunit binds to the DNA (non specifically); The beta' subunit contains five domains. The protein contains the domains 1, 2, 3, 4 and 5 that represent the clamp domain, the binding site of magnesium ion, the pore domain, the funnel domain and the discontinuous cleft domain that is required to form the central channel where the DNA is bound respectively; Localized in the cytoplasm; High confidence in function and specificity; DNA-dependent RNA polymerase subunit beta 802487 rpoC 10977238 rpoC Zobellia galactanivorans DNA-dependent RNA polymerase subunit beta YP_004735105.1 798189 R 63186 CDS YP_004735106.1 340616653 10978526 complement(802542..806351) 1 NC_015844.1 The beta subunit of RNA polymerase, in association with the beta subunit, omega subunit and the two alpha subunits, forms the polymerase core. The beta subunit possesses the polymerase activity; It contains seven domains. The domains 1 and 2 form the two distinctive lobes of the protein, the domain 3 or fork domain is proximal to catalytic site, the domain 6 is the heteroduplex binding domain and the domain 7 or clamp region has a zinc-binding motif and interacts with the clamp domain found in the beta' subunit; Localized in the cytoplasm; High confidence in function and specificity; DNA-dependent RNA polymerase subunit beta 806351 rpoB 10978526 rpoB Zobellia galactanivorans DNA-dependent RNA polymerase subunit beta YP_004735106.1 802542 R 63186 CDS YP_004735107.1 340616654 10978525 complement(806496..806873) 1 NC_015844.1 Ribosomal protein L7/L12 are two proteins from the large ribosomal subunit (50S) present in four copies organized as two dimers. The L7/L12 dimer probably interacts with EF-Tu. L7 and L12 only differ in a single post translational modification of the addition an acetyl group to the N terminus of L7; The N-terminal domain of L7/12 is required for dimer formation and for binding to ribosomal protein L10 to form a very strong complex called L8. The C-terminal domain of L7/12 is required for translation factors binding; Belongs to the ribosomal protein L12b/L12e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L7/L12 806873 rplL 10978525 rplL Zobellia galactanivorans 50S ribosomal protein L7/L12 YP_004735107.1 806496 R 63186 CDS YP_004735108.1 340616655 10978502 complement(806927..807442) 1 NC_015844.1 Ribosomal protein L10 is one of the proteins from the large ribosomal subunit (50S). With a dimer of ribosomal proteins L7/12, it forms the L8 complex. Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA; Belongs to the ribosomal proteins L10p/L10e family; localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L10 807442 rplJ 10978502 rplJ Zobellia galactanivorans 50S ribosomal protein L10 YP_004735108.1 806927 R 63186 CDS YP_004735109.1 340616656 10978500 complement(807471..808160) 1 NC_015844.1 Ribosomal protein L1 is the largest protein from the large ribosomal subunit (50S), known to bind very close to the 3' end of the 23S rRNA; Forms part of the L1 stalk; The ribosmal protein L1 is located in the neighborhood of the site where elongation factor Tu is bound to the ribosome; The ribosomal protein L1 is also a translational repressor protein of the L11 operon by binding to its mRNA; Belongs to the ribosomal L1p/L10Ae family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L1 808160 rplA 10978500 rplA Zobellia galactanivorans 50S ribosomal protein L1 YP_004735109.1 807471 R 63186 CDS YP_004735110.1 340616657 10978493 complement(808181..808618) 1 NC_015844.1 Ribosomal protein L11 is one of the proteins from the large ribosomal subunit (50S), known to bind directly to the 23S rRNA; Forms the L11 stalk, which is mobile in the ribosome, indicating its contribution to the activity of initiation, elongation and release factors; The N-terminal domain of ribosomal protein L11 adopts an alpha/beta fold and is followed by the RNA binding C-terminal domain; Belongs to the ribosomal proteins family L11p/L12e; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L11 808618 rplK 10978493 rplK Zobellia galactanivorans 50S ribosomal protein L11 YP_004735110.1 808181 R 63186 CDS YP_004735111.1 340616658 10978501 complement(808686..809237) 1 NC_015844.1 The transcription anti-termination protein influences transcription termination and anti-termination. It is a transcriptional elongation factor of the transcription complex that interacts with the termination factor rho and RNA polymerase; Contains a C-terminal KOW (Kyrpides, Ouzounis, Woese) motif involved in the nucleic acid interaction; Localized in the cytoplasm; High confidence in function and specificity; transcription antitermination protein 809237 nusG 10978501 nusG Zobellia galactanivorans transcription antitermination protein YP_004735111.1 808686 R 63186 CDS YP_004735112.1 340616659 10974042 complement(809599..810786) 1 NC_015844.1 EF-Tu binds GTP and an aminoacyl-tRNA and delivers the latter to the A-site of ribosomes during protein biosynthesis. Its GTPase activity is stimulated by recognition of the mRNA codon by the aminoacyl-tRNA anticodon; EF-Tu consists of three structural domains: the N-terminal domain binds the GTP, the second domain is involved in binding to charged tRNA and the C-terminal domain is involved in binding to both charged tRNA and binding to EF-Ts; Localized in the cytoplasm; High confidence in function and specificity; translation elongation factor Tu 810786 tufA 10974042 tufA Zobellia galactanivorans translation elongation factor Tu YP_004735112.1 809599 R 63186 CDS YP_004735113.1 340616660 10974057 complement(811401..811703) 1 NC_015844.1 Probably modulates the activity of sigma-54 factor; Belongs to the sigma-54 modulation protein/ribosomal protein S30EA family; Localized in the cytoplasm; Function unclear; sigma-54 modulation protein 811703 rpoX 10974057 rpoX Zobellia galactanivorans sigma-54 modulation protein YP_004735113.1 811401 R 63186 CDS YP_004735114.1 340616661 10978530 complement(811743..812633) 1 NC_015844.1 Tyrosine recombinase XerC acts by catalyzing the cutting and rejoining of the recombining DNA molecules utilizing a catalytic tyrosine for the strand cleavage; Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids at ColE1 xer (or cer) and pSC101 (or psi) sites; Belongs to the \\phage\\ integrase family, XerD and XerC integrases subfamily; Localized in the cytoplasm; High confidence in function and specificity; tyrosine recombinase XerC 812633 xerC 10978530 xerC Zobellia galactanivorans tyrosine recombinase XerC YP_004735114.1 811743 R 63186 CDS YP_004735115.1 340616662 10978760 complement(813095..814264) 1 NC_015844.1 Acyl-CoA dehydrogenases catalyze the alpha,beta-dehydrogenation of acyl-CoA thioesters to the corresponding trans 2,3-enoyl CoA-products with concommitant reduction of enzyme-bound FAD. Reoxidation of the flavin involves transfer of electrons to ETF (electron transfering flavoprotein). These enzymes are homodimers containing one molecule of FAD; Localized in the cytoplasm; Specificity unclear; acyl-CoA dehydrogenase 814264 10978760 zobellia_658 Zobellia galactanivorans acyl-CoA dehydrogenase YP_004735115.1 813095 R 63186 CDS YP_004735116.1 340616663 10977239 complement(814276..815166) 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 815166 10977239 zobellia_659 Zobellia galactanivorans membrane protein YP_004735116.1 814276 R 63186 CDS YP_004735117.1 340616664 10977240 complement(815181..817250) 1 NC_015844.1 This permease transports alanine in association with sodium ions. It forms a channel through the cytoplasmic membrane, the interior face being hydrophilic to allow the passage of alanine molecules and sodium ions. Features eleven transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; sodium / alanine symporter 817250 10977240 zobellia_660 Zobellia galactanivorans sodium / alanine symporter YP_004735117.1 815181 R 63186 CDS YP_004735118.1 340616665 10977241 complement(817362..818375) 1 NC_015844.1 This channel transports potassium ion in response to intracellular calcium ion binding. Eight RCK domains (regulators of K+ conductance) form a gating ring at the intracellular membrane surface. The gating ring uses the free energy of Ca2+ binding in a simple manner to perform mechanical work to open the pore. This channel is a homotetramer and the monomer subunit features three transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; calcium-gated potassium channel 818375 mthK 10977241 mthK Zobellia galactanivorans calcium-gated potassium channel YP_004735118.1 817362 R 63186 CDS YP_004735119.1 340616666 10978198 complement(818372..818599) 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 818599 10978198 zobellia_662 Zobellia galactanivorans membrane protein YP_004735119.1 818372 R 63186 CDS YP_004735120.1 340616667 10977242 complement(818673..819986) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 819986 10977242 zobellia_663 Zobellia galactanivorans hypothetical protein YP_004735120.1 818673 R 63186 CDS YP_004735121.1 340616668 10977243 complement(820115..820426) 1 NC_015844.1 Thiosulfate sulfurtransferase catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide; The relatively low affinity of GlpE for both thiosulfate and cyanide suggests that these compounds are not the physiological substrates. Thioredoxin 1 or related dithiol proteins could instead be the physiological sulfur-acceptor substrate; Contains one only rhodanese domain; Localized in the cytoplasm; High confidence in function and specificity; thiosulfate sulfurtransferase 820426 glpE1 10977243 glpE1 Zobellia galactanivorans thiosulfate sulfurtransferase YP_004735121.1 820115 R 63186 CDS YP_004735122.1 340616669 10977921 820588..821034 1 NC_015844.1 The transcriptional regulators with the marR-type HTH domain control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents. Many of the marR-like regulators respond to aromatic compounds; Contains a DNA-binding, winged helix-turn-helix (wHTH) domain; Localized in the cytoplasm; Family membership; MarR-type transcriptional regulator 821034 10977921 zobellia_665 Zobellia galactanivorans MarR-type transcriptional regulator YP_004735122.1 820588 D 63186 CDS YP_004735123.1 340616670 10977244 821076..821651 1 NC_015844.1 Conserved hypothetical protein that belongts to the YceI like family; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; hypothetical protein 821651 10977244 zobellia_666 Zobellia galactanivorans hypothetical protein YP_004735123.1 821076 D 63186 CDS YP_004735124.1 340616671 10977245 821890..823287 1 NC_015844.1 The anthranilate synthase catalyzes the formation of anthranilate from chorismate and L-glutamine, the first step in the biosynthesis of tryptophan. The enzyme is a Tetramer of two components I and two components II. The component I only catalyzes the formation of anthranilate using chorismate and ammonia rather than glutamine; The anthranilate synthase is regulated by feedback inhibition by tryptophan; Belongs to the anthranilate synthase component I family; Localized in the cytoplasm; High confidence in function and specificity; anthranilate synthase, component I 823287 trpE 10977245 trpE Zobellia galactanivorans anthranilate synthase, component I YP_004735124.1 821890 D 63186 CDS YP_004735125.1 340616672 10978697 823290..823853 1 NC_015844.1 The anthranilate synthase catalyzes the formation of anthranilate from chorismate and L-glutamine, the first step in the biosynthesis of tryptophan. The enzyme is a Tetramer of two components I and two components II. Associated with the component I, the component II of the anthranilate synthase provides the glutamine amidotransferase activity (GATase, 2.4.2.-) that catalyses the removal of the ammonia group from a glutamate molecule and its subsequent transfer to a specific substrate, thus creating a new carbon-nitrogen group on the substrate; Consists of a type-1 glutamine amidotransferase domain; Localized in the cytoplasm; High confidence in function and specificity; anthranilate synthase component II (glutamine amidotransferase) 823853 trpG 10978697 trpG Zobellia galactanivorans anthranilate synthase component II (glutamine amidotransferase) YP_004735125.1 823290 D 63186 CDS YP_004735126.1 340616673 10978699 823911..824906 1 NC_015844.1 This enzyme is a part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan from chorismate. It catalyses the formation of N-(5-phospho-D-ribosyl)-anthranilate from anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate, the second step in the biosynthesis of tryptophan; Belongs to the anthranilate phosphoribosyltransferase family; Localized in the cytoplasm; High confidence in function and specificity; anthranilate phosphoribosyltransferase 824906 trpD 10978699 trpD Zobellia galactanivorans anthranilate phosphoribosyltransferase YP_004735126.1 823911 D 63186 CDS YP_004735127.1 340616674 10978696 824932..825714 1 NC_015844.1 Indole-3-glycerol phosphate synthase (IGPS) catalyzes the ring closure of 1-(2-carboxy-phenylamino)-1-deoxyribulose into indol-3-glycerol-phosphate, the fourth step in the biosynthesis of tryptophan; Localized in the cytoplasm; High confidence in function and specificity; indole-3-glycerol phosphate synthase 825714 trpC 10978696 trpC Zobellia galactanivorans indole-3-glycerol phosphate synthase YP_004735127.1 824932 D 63186 CDS YP_004735128.1 340616675 10978695 825715..826419 1 NC_015844.1 The N-(5'-phosphoribosyl)anthranilate isomerase (PRAI) converts the N-(5-phospho-beta-D-ribosyl)anthranilate to 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate, the third step in the biosynthesis of tryptophan; Localized in the cytoplasm; High confidence in function and specificity; N-(5'-phosphoribosyl)anthranilate isomerase 826419 trpF 10978695 trpF Zobellia galactanivorans N-(5'-phosphoribosyl)anthranilate isomerase YP_004735128.1 825715 D 63186 CDS YP_004735129.1 340616676 10978698 826479..827663 1 NC_015844.1 The tryptophan synthase catalyzes the fifth and the last step in the biosynthesis of tryptophan. It is a tetramer of two alpha and two beta chains. The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine; Uses the pyridoxal phosphate (vitamin B6) as cofactor; Localized in the cytoplasm; High confidence in function and specificity; tryptophan synthase subunit beta 827663 trpB1 10978698 trpB1 Zobellia galactanivorans tryptophan synthase subunit beta YP_004735129.1 826479 D 63186 CDS YP_004735130.1 340616677 10978693 827755..828519 1 NC_015844.1 The tryptophan synthase catalyzes the fifth and the last step in the biosynthesis of tryptophan. It is a tetramer of two alpha and two beta chains. The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate; Uses the pyridoxal phosphate (vitamin B6) as cofactor; Localized in the cytoplasm; High confidence in function and specificity; tryptophan synthase subunit alpha 828519 trpA 10978693 trpA Zobellia galactanivorans tryptophan synthase subunit alpha YP_004735130.1 827755 D 63186 CDS YP_004735131.1 340616678 10978692 828545..828772 1 NC_015844.1 Contains two transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 828772 10978692 zobellia_674 Zobellia galactanivorans membrane protein YP_004735131.1 828545 D 63186 CDS YP_004735132.1 340616679 10977246 828820..829791 1 NC_015844.1 Seems to possess a signal peptide possibly cleaved between the residues 18 and 19; Could be localized in the periplasmic space; hypothetical protein 829791 10977246 zobellia_675 Zobellia galactanivorans hypothetical protein YP_004735132.1 828820 D 63186 CDS YP_004735133.1 340616680 10977247 complement(829862..832408) 1 NC_015844.1 Phosphoenolpyruvate carboxylase supplies oxaloacetate to the tricarboxylic acid cycle, which requires continuous input of C4 molecules in order to replenish the intermediates removed for amino acid biosynthesis. It forms an homotetramer; Belongs to the PEPCase family; Localized in the cytoplasm; High confidence in function and specificity; phosphoenolpyruvate carboxylase 832408 ppcA 10977247 ppcA Zobellia galactanivorans phosphoenolpyruvate carboxylase YP_004735133.1 829862 R 63186 CDS YP_004735134.1 340616681 10978369 complement(832714..833379) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 833379 10978369 zobellia_677 Zobellia galactanivorans hypothetical protein YP_004735134.1 832714 R 63186 CDS YP_004735135.1 340616682 10977248 complement(833395..836847) 1 NC_015844.1 Pyruvate carboxylase catalyzes a 2-step reaction, involving, in the first step, the ATP-dependent carboxylation of the covalently attached biotin and, in the second, the transfer of the carboxyl group to pyruvate. PycA has three functional domains: a biotin carboxylase (BC) domain, a carboxyltransferase (CT) domain which perform the second part of the reaction and a biotinyl domain; Localized in the cytoplasm; High confidence in function and specificity; pyruvate carboxylase 836847 pycA 10977248 pycA Zobellia galactanivorans pyruvate carboxylase YP_004735135.1 833395 R 63186 CDS YP_004735136.1 340616683 10978415 837045..837173 1 NC_015844.1 Contains, in its N-terminal part, a domain Localized in the cytoplasm; hypothetical protein 837173 10978415 zobellia_679 Zobellia galactanivorans hypothetical protein YP_004735136.1 837045 D 63186 CDS YP_004735137.1 340616684 10977249 complement(837175..837936) 1 NC_015844.1 Protein containing a DUF328 domain; Belongs to the UPF0246 family; Localized in the cytoplasm; hypothetical protein 837936 10977249 zobellia_680 Zobellia galactanivorans hypothetical protein YP_004735137.1 837175 R 63186 CDS YP_004735138.1 340616685 10977251 complement(838042..839070) 1 NC_015844.1 Enzyme responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA by rotation of the C1'-N-1 glycosidic bond of uridine to a C1'-C5; Contains a N-terminal S4 RNA- binding domain that probably mediates binding to RNA; Belongs to the pseudouridine synthase RluA family; localized in the cytoplasm; High confidence in function and specificity; ribosomal large subunit pseudouridine synthase D 839070 rluD 10977251 rluD Zobellia galactanivorans ribosomal large subunit pseudouridine synthase D YP_004735138.1 838042 R 63186 CDS YP_004735139.1 340616686 10978471 complement(839074..839661) 1 NC_015844.1 Conserved protein containing two PASTA domains (Pbp And Serine/Threonine kinase Associated domains). Such domains bind the beta-lactam stem, which implicates it in sensing D-alanyl-D-alanine. PASTA domain adopts a small globular fold consisting of 3 beta-sheets and an alpha-helix; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Family membership; PASTA domain-containing protein 839661 10978471 zobellia_682 Zobellia galactanivorans PASTA domain-containing protein YP_004735139.1 839074 R 63186 CDS YP_004735140.1 340616687 10977252 839755..840735 1 NC_015844.1 D-alanine-D-alanine ligase is one of the central enzyme of the cross-linking step of peptidoglycan assembly. It catalyzes the reaction: ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. Uses ATP as a cofactor. Localized in the cytoplasm.; High confidence in function and specificity; D-alanine--D-alanine ligase 840735 ddlA 10977252 ddlA Zobellia galactanivorans D-alanine--D-alanine ligase YP_004735140.1 839755 D 63186 CDS YP_004735141.1 340616688 10977726 840780..841235 1 NC_015844.1 Phosphopantetheine adenylyltransferase is involved in the biosynthesis of coenzyme A from pantothenate. It reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA and pyrophosphate. It forms a homohexamer. Localized in the cytoplasm.; High confidence in function and specificity; phosphopantetheine adenylyltransferase 841235 coaD 10977726 coaD Zobellia galactanivorans phosphopantetheine adenylyltransferase YP_004735141.1 840780 D 63186 CDS YP_004735142.1 340616689 10977662 841442..843292 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains one N-terminal PAS/PAC domain involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 843292 10977662 zobellia_685 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004735142.1 841442 D 63186 CDS YP_004735143.1 340616690 10977253 843279..843683 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity that acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership; two-component system-response regulator, receiver domain 843683 10977253 zobellia_686 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004735143.1 843279 D 63186 CDS YP_004735144.1 340616691 10977254 843718..845493 1 NC_015844.1 Metallocarboxypeptidases remove aminoacid residues from the C-terminal end of proteins. The single catalytic zinc ion is tetrahedrally coordinated by two histidines and a glutamate, as well as a water molecule. One of the histidines and the glutamate occur in the motif His-Xaa-Xaa-Glu; Belongs to the family M14 of peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the outer membrane; Specificity unclear; metallopeptidase 4 845493 10977254 zobellia_687 Zobellia galactanivorans metallopeptidase 4 YP_004735144.1 843718 D 63186 CDS YP_004735145.1 340616692 10977255 complement(845499..846086) 1 NC_015844.1 This conserved protein belongs to the Nudix (NUcleoside DIphosphate linked to some other moiety X) hydrolase family. Its specificity is unclear; Localized in the cytoplasm; Family membership; NUDIX hydrolase 846086 10977255 zobellia_688 Zobellia galactanivorans NUDIX hydrolase YP_004735145.1 845499 R 63186 CDS YP_004735146.1 340616693 10977256 846094..846735 1 NC_015844.1 Orotate phosphoribosyltransferase is involved in pyrimidine biosynthesis. It catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribosyl-1-pyrophosphate to orotate, leading to the formation of orotidine monophosphate. It forms a homodimer and binds one magnesium ion per subunit as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; orotate phosphoribosyltransferase 846735 pyrE 10977256 pyrE Zobellia galactanivorans orotate phosphoribosyltransferase YP_004735146.1 846094 D 63186 CDS YP_004735147.1 340616694 10978420 846743..847135 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 847135 10978420 zobellia_690 Zobellia galactanivorans hypothetical protein YP_004735147.1 846743 D 63186 CDS YP_004735148.1 340616695 10977258 complement(847136..847867) 1 NC_015844.1 Biotin-[acetyl-CoA-carboxylase]ligase is responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. These enzymes usually transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. Localized in the cytoplasm.; High confidence in function and specificity; biotin-[acetyl-CoA-carboxylase] ligase 847867 10977258 zobellia_691 Zobellia galactanivorans biotin-[acetyl-CoA-carboxylase] ligase YP_004735148.1 847136 R 63186 CDS YP_004735149.1 340616696 10977259 847960..848343 1 NC_015844.1 Conserved protein belonging to the Iojap family. In maize, iojap is a pattern-striping gene, reflecting a chloroplast development defect in some cells. The role of iojap in chloroplast development, and the role of its bacterial orthologs, is unclear; Localized in the cytoplasm; Family membership; Iojap family protein 848343 10977259 zobellia_692 Zobellia galactanivorans Iojap family protein YP_004735149.1 847960 D 63186 CDS YP_004735150.1 340616697 10977260 848353..850362 1 NC_015844.1 FtsH is a membrane-anchored ATP-dependent metalloprotease involved in membrane functions, cell cycle control, and gene expression. It only efficiently degrades misfolded or misassembled membrane proteins as well as a subset of cytoplasmic regulatory proteins (as the heat-shock transcription factor sigma 32) that have a low thermodynamic stability. it is a fundamental prokaryotic self-protection mechanism that checks if proteins are correctly folded; Binds 1 zinc ion; Contains two N-terminal transmembrane segments; belongs, in the N-terminal part, to the AAA ATPase family and, in the C-terminal part, to the peptidase M41 family (clan (MA(E)); Localized in the cytpolasmic membrane; High confidence in function and specificity; cell division protein FtsH 850362 ftsH 10977260 ftsH Zobellia galactanivorans cell division protein FtsH YP_004735150.1 848353 D 63186 CDS YP_004735151.1 340616698 10977847 850421..851035 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 851035 10977847 zobellia_694 Zobellia galactanivorans hypothetical protein YP_004735151.1 850421 D 63186 CDS YP_004735152.1 340616699 10977261 851037..851840 1 NC_015844.1 Phosphatidate cytidylyltransferase is essential for phospholipid biosynthesis. It catalyzes the synthesis of CDP-diacylglycerol from CTP and phosphatidate: CDP-diacylglycerol is an important branch point intermediate in both prokaryotic and eukaryotic organisms. Features seven transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; phosphatidate cytidylyltransferase 851840 cdsA 10977261 cdsA Zobellia galactanivorans phosphatidate cytidylyltransferase YP_004735152.1 851037 D 63186 CDS YP_004735153.1 340616700 10977642 851830..852513 1 NC_015844.1 Phosphatidylserine decarboxylase plays a central role in the biosynthesis of aminophospholipids by converting phosphatidylserine to phosphatidylethanolamine. It uses a pyruvate group as cofactor. Two nonidentical subunits of the mature enzyme are formed by cleavage of the proenzyme resulting in the conversion of the catalytic Serine to an amino-terminal pyruvate residue. Localized in the cytoplasm.; High confidence in function and specificity; phosphatidylserine decarboxylase proenzyme 852513 psd 10977642 psd Zobellia galactanivorans phosphatidylserine decarboxylase proenzyme YP_004735153.1 851830 D 63186 CDS YP_004735154.1 340616701 10978393 852488..852754 1 NC_015844.1 Acyl-CoA binding protein (ACBP) is a small (~10 kDa) protein that binds medium- and long-chain acyl-CoA esters with high affinity, and may act as an intra- cellular carrier of acyl-CoA esters. It is a mainly-alpha protein, consisting of 5 short alpha-helices and 3 connecting beta-strands. Localized in the cytoplasm.; Family membership; acyl-CoA binding protein 852754 10978393 zobellia_697 Zobellia galactanivorans acyl-CoA binding protein YP_004735154.1 852488 D 63186 CDS YP_004735155.1 340616702 10977262 complement(852787..853551) 1 NC_015844.1 Conserved protein belonging to the creatinase family, but its exact function is unclear; Localized in the cytoplasm; Family membership; creatinase family protein 853551 10977262 zobellia_698 Zobellia galactanivorans creatinase family protein YP_004735155.1 852787 R 63186 CDS YP_004735156.1 340616703 10977263 complement(853589..854857) 1 NC_015844.1 Conserved protein belonging to the Fatty acid hydroxylase family which includes fatty acid and carotene hydroxylases and sterol desaturases; Contains eight transmembrane helices; Localized in the cytoplasmic membrane; Family membership; fatty acid hydroxylase family protein 854857 10977263 zobellia_699 Zobellia galactanivorans fatty acid hydroxylase family protein YP_004735156.1 853589 R 63186 CDS YP_004735157.1 340616704 10977264 complement(854907..855500) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 16 and 17; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 855500 10977264 zobellia_700 Zobellia galactanivorans periplasmic protein YP_004735157.1 854907 R 63186 CDS YP_004735158.1 340616705 10977266 complement(855796..856365) 1 NC_015844.1 Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership; TetR family transcriptional regulator 856365 10977266 zobellia_701 Zobellia galactanivorans TetR family transcriptional regulator YP_004735158.1 855796 R 63186 CDS YP_004735159.1 340616706 10977267 complement(856596..859226) 1 NC_015844.1 Valyl-tRNA synthetase catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a \\posttransfer\\ editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner. Belongs to the class-I aminoacyl-tRNA synthetase family. Localized in the cytoplasm.; High confidence in function and specificity; valyl-tRNA synthetase 859226 valS 10977267 valS Zobellia galactanivorans valyl-tRNA synthetase YP_004735159.1 856596 R 63186 CDS YP_004735160.1 340616707 10978743 859426..859800 1 NC_015844.1 Conserved protein belonging to the DUF1573 family, which includes proteins of unknown function conserved in bacteria such as Rhodopirellula baltica, Bacteroides thetaiotaomicron, and Porphyromonas gingivalis; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; hypothetical protein 859800 10978743 zobellia_703 Zobellia galactanivorans hypothetical protein YP_004735160.1 859426 D 63186 CDS YP_004735161.1 340616708 10977268 complement(859862..861193) 1 NC_015844.1 Conserved protein containing a N-terminal domain of unknonwn function and a C-terminal PDZ domain. PDZ domains bind either the carboxyl-terminal sequences of proteins or internal peptide sequences; Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; hypothetical protein 861193 10977268 zobellia_704 Zobellia galactanivorans hypothetical protein YP_004735161.1 859862 R 63186 CDS YP_004735162.1 340616709 10977269 861279..862526 1 NC_015844.1 Aspartate aminotransferase or Transaminase A or Glutamic-aspartic transaminase or Glutamic-oxaloacetic transaminase converts the L-aspartic acid and the 2-oxoglutarate into L-glutamate and oxaloacetate using the Pyridoxal phosphate as cofactor bound by covalent linkage to a lysine residue; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity; aspartate aminotransferase 862526 aatB 10977269 aatB Zobellia galactanivorans aspartate aminotransferase YP_004735162.1 861279 D 63186 CDS YP_004735163.1 340616710 10977457 862526..863542 1 NC_015844.1 Cytoplasmic protein also called UDP-N-acetylmuramate dehydrogenase; Uses the FAD as cofactor; This enzyme participates to the cell wall formation as a part of the pathway for the biosynthesis of the UDP-N-acetylmuramoyl-pentapeptide, which is a precursor of bacterial peptidoglycan.; High confidence in function and specificity; UDP-N-acetylenolpyruvoylglucosamine reductase 863542 murB 10977457 murB Zobellia galactanivorans UDP-N-acetylenolpyruvoylglucosamine reductase YP_004735163.1 862526 D 63186 CDS YP_004735164.1 340616711 10978200 863746..864312 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 864312 10978200 zobellia_707 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004735164.1 863746 D 63186 CDS YP_004735165.1 340616712 10977270 864317..865075 1 NC_015844.1 Contains one transmembrane segment; Probably localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 865075 10977270 zobellia_708 Zobellia galactanivorans membrane protein YP_004735165.1 864317 D 63186 CDS YP_004735166.1 340616713 10977271 865161..865379 1 NC_015844.1 Signal peptide putatively cleaved between the residues 19 and 20; Probably localized in the periplasmic space; Hypothetical protein; hypothetical protein 865379 10977271 zobellia_709 Zobellia galactanivorans hypothetical protein YP_004735166.1 865161 D 63186 CDS YP_004735167.1 340616714 10977272 865405..865959 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 865959 10977272 zobellia_710 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004735167.1 865405 D 63186 CDS YP_004735168.1 340616715 10977273 866081..866956 1 NC_015844.1 Catalyzes the radical-mediated insertion of two sulfur atoms into an octanoyl group bound to acyl carrier protein (ACP) to produce a lipoyl group; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Also binds 1 3Fe-4S cluster; Localized in the cytoplasm; High confidence in function and specificity; lipoyl synthase 866956 lipA 10977273 lipA Zobellia galactanivorans lipoyl synthase YP_004735168.1 866081 D 63186 CDS YP_004735169.1 340616716 10978093 867051..868061 1 NC_015844.1 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis (Embden-Meyerhof pathway) and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3- phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity; glyceraldehyde 3-phosphate dehydrogenase 868061 gapC 10978093 gapC Zobellia galactanivorans glyceraldehyde 3-phosphate dehydrogenase YP_004735169.1 867051 D 63186 CDS YP_004735170.1 340616717 10977879 868058..870286 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. The cytoplasmic part of the protein consists of the histidine kinase domain and of the receiver domain of the response regulator that is phosphorylated by the histidine kinase domain. A transmembrane segment separates this part from the periplasmic part that contains three tetratrico peptide repeats; Localized in the cytoplasmic membrane; Family membership; two-component system hybrid-sensor histidine kinase/response regulator, receiver domain 870286 10977879 zobellia_713 Zobellia galactanivorans two-component system hybrid-sensor histidine kinase/response regulator, receiver domain YP_004735170.1 868058 D 63186 CDS YP_004735171.1 340616718 10977274 complement(870279..871274) 1 NC_015844.1 Tetraacyldisaccharide 4'-kinase is involved in the synthesis of lipid A portion of the bacterial lipopolysaccharides. It transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). Features a N-terminal transmembrane helix. Localized in the cytoplasmic membrane.; High confidence in function and specificity; tetraacyldisaccharide 4'-kinase 871274 lpxK 10977274 lpxK Zobellia galactanivorans tetraacyldisaccharide 4'-kinase YP_004735171.1 870279 R 63186 CDS YP_004735172.1 340616719 10978107 871323..872417 1 NC_015844.1 Conserved protein belonging to the NIF3 family. NIF3 is a yeast protein interacting with the transcriptional coactivator NGG1p which is part of the ADA complex. The exact function of this interaction is unknown; Localized in the cytoplasm; Family membership; NIF3 family protein 872417 10978107 zobellia_715 Zobellia galactanivorans NIF3 family protein YP_004735172.1 871323 D 63186 CDS YP_004735173.1 340616720 10977275 872423..873202 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 873202 10977275 zobellia_716 Zobellia galactanivorans hypothetical protein YP_004735173.1 872423 D 63186 CDS YP_004735174.1 340616721 10977276 complement(873269..874609) 1 NC_015844.1 Kynurenine 3-monooxygenase plays a key role in the catabolism of tryptophan by catalyzing the hydroxylation of Kynurenine to 3-hydroxykynurenine; This enzyme is NADPH-dependent, uses the FAD as cofactor and adopts a Rossmann fold; Contains one N-terminal transmembrane segment; Belongs to the aromatic-ring hydroxylase family; Localized in the cytoplasmic membrane; High confidence in function and specificity; Kynurenine 3-monooxygenase 874609 kmoA 10977276 kmoA Zobellia galactanivorans Kynurenine 3-monooxygenase YP_004735174.1 873269 R 63186 CDS YP_004735175.1 340616722 10978068 complement(874936..875565) 1 NC_015844.1 Endopeptidase Clp plays a major role in the degradation of misfolded proteins. It is an oligomeric complex constituted by an ATP-binding subunit (ClpX) and a peptidase subunit (ClpP). The subunits form two different ring structures consisting of seven peptidase subunits and six ATP-binding subunits, respectively. In absence of ClpX, ClpP can act only on oligopeptides; Belongs to the family S14 of the peptidases; Localized in the cytoplasm; High confidence in function and specificity; endopeptidase Clp, peptidase subunit 875565 clpP2 10978068 clpP2 Zobellia galactanivorans endopeptidase Clp, peptidase subunit YP_004735175.1 874936 R 63186 CDS YP_004735176.1 340616723 10977654 875676..876374 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 23 and 24; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 876374 10977654 zobellia_719 Zobellia galactanivorans membrane protein YP_004735176.1 875676 D 63186 CDS YP_004735177.1 340616724 10977277 complement(876387..877532) 1 NC_015844.1 The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. Features twelve transmembrane helices. Localized in the cytoplasmic membrane.; Family membership; major facilitator family transporter 877532 10977277 zobellia_720 Zobellia galactanivorans major facilitator family transporter YP_004735177.1 876387 R 63186 CDS YP_004735178.1 340616725 10977278 complement(877671..878747) 1 NC_015844.1 Flavastacin is a zinc metallendopeptidase that hydrolyzes polypeptides on the amino-side of Asp in -Xaa-|-Asp-. Acts very slowly on -Xaa-|-Glu. Displays a o-glycosylation consisting of a Man, GlcNAc, GlcU, Glc, GlcU, Rha, Man heptasaccharide; Belongs to the family M12 of the peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 32 and 33; Localized in the outer membrane; High confidence in function and specificity; flavastacin 2 878747 10977278 zobellia_721 Zobellia galactanivorans flavastacin 2 YP_004735178.1 877671 R 63186 CDS YP_004735179.1 340616726 10977279 complement(878924..880195) 1 NC_015844.1 Kynureninase, involved in the catabolism of L-tryptophan, converts the L-kynurenine to anthranilate and L-alanine; Uses pyridoxal-5'-phosphate as cofactor; Belongs to the PLP dependent aminotransferase superfamily; Localized in the cytoplasm; High confidence in function and specificity; Kynureninase 880195 kynU 10977279 kynU Zobellia galactanivorans Kynureninase YP_004735179.1 878924 R 63186 CDS YP_004735180.1 340616727 10978070 complement(880245..880712) 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 880712 10978070 zobellia_723 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004735180.1 880245 R 63186 CDS YP_004735181.1 340616728 10977280 880781..881422 1 NC_015844.1 MdmC is a 4-O-methyltransferase for the lactone ring of midecamycin and other macrolide antibiotics; Localized in the cytoplasm; High confidence in function and specificity; O-methyltransferase 881422 mdmC 10977280 mdmC Zobellia galactanivorans O-methyltransferase YP_004735181.1 880781 D 63186 CDS YP_004735182.1 340616729 10978131 complement(881388..881960) 1 NC_015844.1 Undecaprenyl-diphosphatase catalyzes the hydrolysis of dolichol pyrophosphate, likely in connection with glycosylation reactions of membrane. Features five transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; UDP-diphosphatase 881960 sepP1 10978131 sepP1 Zobellia galactanivorans UDP-diphosphatase YP_004735182.1 881388 R 63186 CDS YP_004735183.1 340616730 10978579 complement(881963..882301) 1 NC_015844.1 TatA is involved in a sec-independent translocation mechanism, termed TAT for twin-arginine translocation system. This system mainly transports proteins with bound cofactors that require folding prior to export. TatA is required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif S/T-R-R-X-F-L-K; Belongs to the mttA/Hcf106 family; Contains a transmembrane helix; Localized in the cytoplasmic membrane; High confidence in function and specificity; Sec-independent protein translocase 882301 tatA 10978579 tatA Zobellia galactanivorans Sec-independent protein translocase YP_004735183.1 881963 R 63186 CDS YP_004735184.1 340616731 10978640 complement(882384..884696) 1 NC_015844.1 Aminopeptidase catalyzes the hydrolysis of N-terminal amino-acid residues from oligopeptides or polypeptides. This enzyme belongs to the family M1 of the peptidases. A catalytic zinc ion is bound by two histidines and a glutamate. The histidines are within an 'HEXXH' motif on one long helix with the glutamate on another antiparallel helix. The catalytic mechanism is believed to involve activation of a water molecule by the zinc ion. The glutamate of the HEXXH motif is known to be important for catalysis and a tyrosine may also be involved. Features a signal peptide cleaved between the residues 21 and 22. Localized in the periplasm.; Specificity unclear; aminopeptidase 884696 10978640 zobellia_727 Zobellia galactanivorans aminopeptidase YP_004735184.1 882384 R 63186 CDS YP_004735185.1 340616732 10977281 complement(884757..885263) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 885263 10977281 zobellia_728 Zobellia galactanivorans periplasmic protein YP_004735185.1 884757 R 63186 CDS YP_004735186.1 340616733 10977282 complement(885314..886144) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 886144 10977282 zobellia_729 Zobellia galactanivorans periplasmic protein YP_004735186.1 885314 R 63186 CDS YP_004735187.1 340616734 10977283 complement(886197..887027) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 887027 10977283 zobellia_730 Zobellia galactanivorans periplasmic protein YP_004735187.1 886197 R 63186 CDS YP_004735188.1 340616735 10977285 complement(887086..887868) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 887868 10977285 zobellia_731 Zobellia galactanivorans periplasmic protein YP_004735188.1 887086 R 63186 CDS YP_004735189.1 340616736 10977286 complement(887855..888604) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein; periplasmic protein 888604 10977286 zobellia_732 Zobellia galactanivorans periplasmic protein YP_004735189.1 887855 R 63186 CDS YP_004735190.1 340616737 10977287 888966..892508 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 892508 10977287 zobellia_733 Zobellia galactanivorans periplasmic protein YP_004735190.1 888966 D 63186 CDS YP_004735191.1 340616738 10977288 892533..893684 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 893684 10977288 zobellia_734 Zobellia galactanivorans periplasmic protein YP_004735191.1 892533 D 63186 CDS YP_004735192.1 340616739 10977289 894048..894782 1 NC_015844.1 Peptidase family M15 contains metallopeptidases, mostly D-ala-Dala carboxypeptidases and dipeptidases involved in peptidoglycan metabolism. These peptidases are zinc-dependent. This cation is bound by conserved residues, two hidistines and one aspartate. Features a twin-arginine signal peptide cleaved between the residues 26 and 27. Localized in the periplasm.; Specificity unclear; metallopeptidase 5 894782 10977289 zobellia_735 Zobellia galactanivorans metallopeptidase 5 YP_004735192.1 894048 D 63186 CDS YP_004735193.1 340616740 10977290 894820..895584 1 NC_015844.1 Peptidase family M48 contains metalloendopeptidases. The single catalytic zinc ion tetrahedrally is co-ordinated by two histidines within an HEXXH motif, an as yet undetermined third residue and water. The glutamate within the HEXXH motif is essential for catalysis. Features a signal peptide cleaved between the residues 20 and 21. Localized in the periplasm.; Specificity unclear; metallopeptidase 895584 10977290 zobellia_736 Zobellia galactanivorans metallopeptidase YP_004735193.1 894820 D 63186 CDS YP_004735194.1 340616741 10977291 complement(896097..896489) 1 NC_015844.1 Conserved protein containing two ankyrin repeats. The ankyrin repeat is involved in protein-protein interaction. Each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90o angle. The repeats stack together to form an L-shaped structure; Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; ankyrin repeat-containing protein 896489 10977291 zobellia_737 Zobellia galactanivorans ankyrin repeat-containing protein YP_004735194.1 896097 R 63186 CDS YP_004735195.1 340616742 10977292 896833..898350 1 NC_015844.1 The 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (PGAM) catalyzes the step 8 of the glycolysis (Embden-Meyerhof pathway). PGAM catalyzes the internal transfer of a phosphate group from C-3 to C-2 which results in the conversion of 3-phosphoglycerate (3PG) to 2-phosphoglycerate (2PG) through a 2,3-bisphosphoglycerate intermediate; Uses 2 manganese ions as cofactors; Belongs to the phosphoglycerate mutase family, BPG-dependent PGAM subfamily; Localized in the cytoplasm; High confidence in function and specificity; 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase 898350 gpmI 10977292 gpmI Zobellia galactanivorans 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase YP_004735195.1 896833 D 63186 CDS YP_004735196.1 340616743 10977948 898384..899202 1 NC_015844.1 Methionyl aminopeptidase cleaves the Met-Xaa bond in the removal of the initiating N-terminal methionine from newly synthesized proteins. Belongs to the family M24 of the metallopeptidases. Requires two co-catalytic ions of cobalt. Localized in the cytoplasm.; High confidence in function and specificity; methionyl aminopeptidase 899202 mapA 10977948 mapA Zobellia galactanivorans methionyl aminopeptidase YP_004735196.1 898384 D 63186 CDS YP_004735197.1 340616744 10978125 899245..900015 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 900015 10978125 zobellia_740 Zobellia galactanivorans hypothetical protein YP_004735197.1 899245 D 63186 CDS YP_004735198.1 340616745 10977294 complement(900012..900956) 1 NC_015844.1 ApbE is involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine (HMP) moiety of thiamine. Localized in the cytoplasm.; High confidence in function and specificity; thiamine biosynthesis protein apbE 900956 apbE1 10977294 apbE1 Zobellia galactanivorans thiamine biosynthesis protein apbE YP_004735198.1 900012 R 63186 CDS YP_004735199.1 340616746 10977523 complement(901012..901380) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 901380 10977523 zobellia_742 Zobellia galactanivorans hypothetical protein YP_004735199.1 901012 R 63186 CDS YP_004735200.1 340616747 10977295 complement(901494..902801) 1 NC_015844.1 NADH-quinone reductase (NQR) complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. This complex is composed of six subunits (nqrA, nqrB, nqrC, nqrD, nqrE and nqrF). The first step is catalyzed by nqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. NrqF binds one 2Fe-2S cluster and one FAD as cofactors. Features a N-terminal transmembrane helix. Localized in the cytoplasmic membrane.; High confidence in function and specificity; Na(+)-translocating NADH-quinone reductase subunit F 902801 nqrF 10977295 nqrF Zobellia galactanivorans Na(+)-translocating NADH-quinone reductase subunit F YP_004735200.1 901494 R 63186 CDS YP_004735201.1 340616748 10978270 complement(902804..903556) 1 NC_015844.1 ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. This complex is composed of six subunits (nqrA, nqrB, nqrC, nqrD, nqrE and nqrF). NqrA to nqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. Features six transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; Na(+)-translocating NADH-quinone reductase subunit E 903556 nqrE 10978270 nqrE Zobellia galactanivorans Na(+)-translocating NADH-quinone reductase subunit E YP_004735201.1 902804 R 63186 CDS YP_004735202.1 340616749 10978269 complement(903578..904225) 1 NC_015844.1 NADH-quinone reductase (NQR) complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. This complex is composed of six subunits (nqrA, nqrB, nqrC, nqrD, nqrE and nqrF). NqrA to nqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. Features five transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; Na(+)-translocating NADH-quinone reductase subunit D 904225 nqrD 10978269 nqrD Zobellia galactanivorans Na(+)-translocating NADH-quinone reductase subunit D YP_004735202.1 903578 R 63186 CDS YP_004735203.1 340616750 10978268 complement(904227..904976) 1 NC_015844.1 NADH-quinone reductase (NQR) complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. This complex is composed of six subunits (nqrA, nqrB, nqrC, nqrD, nqrE and nqrF). NqrA to nqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. Features a N-terminal transmembrane helix. Localized in the cytoplasmic membrane.; High confidence in function and specificity; Na(+)-translocating NADH-quinone reductase subunit C 904976 nqrC 10978268 nqrC Zobellia galactanivorans Na(+)-translocating NADH-quinone reductase subunit C YP_004735203.1 904227 R 63186 CDS YP_004735204.1 340616751 10978267 complement(904979..906253) 1 NC_015844.1 NADH-quinone reductase (NQR) complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. This complex is composed of six subunits (nqrA, nqrB, nqrC, nqrD, nqrE and nqrF). NqrA to nqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. Features eight transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; Na(+)-translocating NADH-quinone reductase subunit B 906253 nqrB 10978267 nqrB Zobellia galactanivorans Na(+)-translocating NADH-quinone reductase subunit B YP_004735204.1 904979 R 63186 CDS YP_004735205.1 340616752 10978266 complement(906257..907609) 1 NC_015844.1 NADH-quinone reductase (NQR) complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. This complex is composed of six subunits (nqrA, nqrB, nqrC, nqrD, nqrE and nqrF). NqrA to nqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. Localized in the cytoplasm.; High confidence in function and specificity; Na(+)-translocating NADH-quinone reductase subunit A 907609 nqrA 10978266 nqrA Zobellia galactanivorans Na(+)-translocating NADH-quinone reductase subunit A YP_004735205.1 906257 R 63186 CDS YP_004735206.1 340616753 10978265 907762..909006 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 909006 10978265 zobellia_749 Zobellia galactanivorans periplasmic protein YP_004735206.1 907762 D 63186 CDS YP_004735207.1 340616754 10977296 909043..910170 1 NC_015844.1 Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 910170 10977296 zobellia_750 Zobellia galactanivorans membrane protein YP_004735207.1 909043 D 63186 CDS YP_004735208.1 340616755 10977297 910183..910569 1 NC_015844.1 The exact function of ApaG is still unknown. ApaG adopts a fibronectin type III (Fn3) fold, with seven antiparallel beta strands forming two beta sheets. In spite of the presence of a putative GXGXXG pyrophosphate binding motif ApaG does not bind ATP or GTP, in vitro. Considering its Fn3 fold, ApaG may be involved in protein- protein interactions. Localized in the cytoplasm.; High confidence in function and specificity; protein ApaG 910569 apaG 10977297 apaG Zobellia galactanivorans protein ApaG YP_004735208.1 910183 D 63186 CDS YP_004735209.1 340616756 10977522 910772..912400 1 NC_015844.1 1-pyrroline-5-carboxylate dehydrogenase is involved in L-proline degradation. It catalyzes the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH. Belongs to the aldehyde dehydrogenase family and uses NAD as cofactor. Localized in the cytoplasm; High confidence in function and specificity; 1-pyrroline-5-carboxylate dehydrogenase 912400 pruA 10977522 pruA Zobellia galactanivorans 1-pyrroline-5-carboxylate dehydrogenase YP_004735209.1 910772 D 63186 CDS YP_004735210.1 340616757 10978392 912522..913034 1 NC_015844.1 DNA damage-inducible (din) genes are coordinately regulated and together compose a global regulatory network that has been termed the SOS-like or SOB regulon.; Conserved hypothetical protein; DinB family protein 913034 10978392 zobellia_753 Zobellia galactanivorans DinB family protein YP_004735210.1 912522 D 63186 CDS YP_004735211.1 340616758 10977298 complement(913579..914214) 1 NC_015844.1 RsmG, also called 16S rRNA 7-methylguanosine methyltransferase and also GidB (glucose-inhibited division protein), is a S-adenosyl-L-methionine dependent methyltransferase that specifically methylates the N7 position of a guanosine in 16S rRNA. It is likely involved in the regulation of cell division; Localized in the cytoplasm; High confidence in function and specificity; ribosomal RNA small subunit methyltransferase G 914214 rsmG 10977298 rsmG Zobellia galactanivorans ribosomal RNA small subunit methyltransferase G YP_004735211.1 913579 R 63186 CDS YP_004735212.1 340616759 10978557 914322..915425 1 NC_015844.1 Linoleoyl-CoA desaturase , also known as delta 6-desaturase, is responsible for the conversion of linoleic acid (18:2) to gamma-linolenic acid (18:3 gamma). It uses iron ion as a cofactor. Features five transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; linoleoyl-CoA desaturase 915425 des6-1 10978557 des6-1 Zobellia galactanivorans linoleoyl-CoA desaturase YP_004735212.1 914322 D 63186 CDS YP_004735213.1 340616760 10977731 915489..916700 1 NC_015844.1 Aspartate aminotransferase or Transaminase A or Glutamic-aspartic transaminase or Glutamic-oxaloacetic transaminase converts the L-aspartic acid and the 2-oxoglutarate into L-glutamate and oxaloacetate using the Pyridoxal phosphate as cofactor bound by covalent linkage to a lysine residue; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity; aspartate aminotransferase 916700 aatA 10977731 aatA Zobellia galactanivorans aspartate aminotransferase YP_004735213.1 915489 D 63186 CDS YP_004735214.1 340616761 10977456 complement(916786..918936) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 918936 10977456 zobellia_757 Zobellia galactanivorans hypothetical protein YP_004735214.1 916786 R 63186 CDS YP_004735215.1 340616762 10977299 complement(919278..920735) 1 NC_015844.1 TrkH is a low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity. Features ten transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; Trk system potassium uptake protein trkH 920735 trkH 10977299 trkH Zobellia galactanivorans Trk system potassium uptake protein trkH YP_004735215.1 919278 R 63186 CDS YP_004735216.1 340616763 10978686 complement(920768..922117) 1 NC_015844.1 TrkA is part of the constitutive potassium transport systems trkG and trkH. May regulate the transport activity of trkG and trkH systems. Binds to NAD+ and NADH. Localized in the cytoplasm.; High confidence in function and specificity; potassium uptake protein TrkA 922117 trkA 10978686 trkA Zobellia galactanivorans potassium uptake protein TrkA YP_004735216.1 920768 R 63186 CDS YP_004735217.1 340616764 10978685 922331..923062 1 NC_015844.1 Methyltransferase that catalyses the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) in the eighth and last step of the menaquinone (vitamin K2) biosynthesis pathway from chorismate; Belongs to the methyltransferase superfamily; Localized in the cytoplasm; High confidence in function and specificity; menaquinone/ubiquinone biosynthesis methyltransferase 923062 menG/ubiE 10978685 menG/ubiE Zobellia galactanivorans menaquinone/ubiquinone biosynthesis methyltransferase YP_004735217.1 922331 D 63186 CDS YP_004735218.1 340616765 10978146 923138..923857 1 NC_015844.1 PorT is essential for the transport of some proteins across the outer membrane from the periplasm to the cell surface. ; Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; High confidence in function and specificity; PorT protein 923857 porT 10978146 porT Zobellia galactanivorans PorT protein YP_004735218.1 923138 D 63186 CDS YP_004735219.1 340616766 10978367 complement(923865..924587) 1 NC_015844.1 Catalyzes the site-specific methylation of the 2' hydroxy group of the ribose in rRNA or tRNA, using the S-AdoMet; Contains a N-terminal RNA 2'-O ribose methyltransferase substrate binding domain and a C-terminal catalytic domain also involved in the dimer formation that adopts an alpha/beta knot fold; Belongs to the RNA methyltransferase TrmH family; Localized in the cytoplasm; Family membership; tRNA/rRNA methyltransferase 924587 10978367 zobellia_762 Zobellia galactanivorans tRNA/rRNA methyltransferase YP_004735219.1 923865 R 63186 CDS YP_004735220.1 340616767 10977301 924776..927388 1 NC_015844.1 Conserved protein belonging to the bacterial surface antigen family; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Function unclear; surface antigen 927388 10977301 zobellia_763 Zobellia galactanivorans surface antigen YP_004735220.1 924776 D 63186 CDS YP_004735221.1 340616768 10977302 927597..928664 1 NC_015844.1 Fructose-bisphosphate aldolase catalyzes the fourth step of the glycolysis (Embden-Meyerhof pathway). It cleaves the hexose D-fructose 1,6-bisphosphate into two trioses sugars: the dihydroxyacetone phosphate (ketone) and the D-glyceraldehyde 3-phosphate (aldehyde); Forms a homodimer and binds two zinc ions per subunit (one is catalytic and the other provides a structural contribution) as cofactor; Belongs to the class II of the fructose-bisphosphate aldolases; Localized in the cytoplasm; High confidence in function and specificity; fructose-bisphosphate aldolase, class II 928664 fbaA 10977302 fbaA Zobellia galactanivorans fructose-bisphosphate aldolase, class II YP_004735221.1 927597 D 63186 CDS YP_004735222.1 340616769 10977817 928692..929576 1 NC_015844.1 The carboxyl transferase subunit beta is a part of the Acetyl-coenzyme A carboxylase complex that catalyzes the first step in long-chain fatty acid biosynthesis. the complex is a heterohexamer of biotin carboxyl carrier protein (accB), biotin carboxylase (accC) and two subunits each of carboxyl transferase subunit alpha (accA) and subunit beta . First, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; Localized in the cytoplasm.; High confidence in function and specificity; acetyl-coenzyme A carboxylase, carboxyl transferase subunit beta 929576 accD 10977817 accD Zobellia galactanivorans acetyl-coenzyme A carboxylase, carboxyl transferase subunit beta YP_004735222.1 928692 D 63186 CDS YP_004735223.1 340616770 10977461 929573..930058 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 930058 10977461 zobellia_766 Zobellia galactanivorans lipoprotein YP_004735223.1 929573 D 63186 CDS YP_004735224.1 340616771 10977303 930165..930434 1 NC_015844.1 Ribosomal protein S15 is one of the primary rRNA binding proteins of the ribosomal small subunit (30S). It binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA; Belongs to the ribosomal protein S15p family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S15 930434 rpsO 10977303 rpsO Zobellia galactanivorans 30S ribosomal protein S15 YP_004735224.1 930165 D 63186 CDS YP_004735225.1 340616772 10978545 930631..932853 1 NC_015844.1 Polyribonucleotide nucleotidyltransferase is involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction. It is also involved in the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation. It forms a homotrimer. Localized in the cytoplasm.; High confidence in function and specificity; polyribonucleotide nucleotidyltransferase 932853 pnpA 10978545 pnpA Zobellia galactanivorans polyribonucleotide nucleotidyltransferase YP_004735225.1 930631 D 63186 CDS YP_004735226.1 340616773 10978357 933017..933880 1 NC_015844.1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. RpoD is usually the primary sigma factor in bacteria. Belongs to the sigma-70 factor family. Localized in the cytoplasm.; High confidence in function and specificity; RNA polymerase sigma factor rpoD 933880 rpoD1 10978357 rpoD1 Zobellia galactanivorans RNA polymerase sigma factor rpoD YP_004735226.1 933017 D 63186 CDS YP_004735227.1 340616774 10978527 934118..934360 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 934360 10978527 zobellia_770 Zobellia galactanivorans hypothetical protein YP_004735227.1 934118 D 63186 CDS YP_004735228.1 340616775 10977305 934364..934813 1 NC_015844.1 YibK methylates the 2' hydroxy group of ribose moieties in rRNA or tRNA. The catalytic domain adopts an alpha/beta knot fold and binds the S-adenosyl methionine cofactor. This domain is also involved in the dimer formation. Localized in the cytoplasm.; Specificity unclear; tRNA/rRNA 2O-methyltransferase YibK 934813 yibK 10977305 yibK Zobellia galactanivorans tRNA/rRNA 2O-methyltransferase YibK YP_004735228.1 934364 D 63186 CDS YP_004735229.1 340616776 10978786 934943..935962 1 NC_015844.1 Adenosine deaminase catalyzes the hydrolytic deamination of adenosine into inosine. It is involved in purine ribonucleoside monophosphate biosynthesis. Localized in the cytoplasm.; High confidence in function and specificity; adenosine deaminase 935962 add 10978786 add Zobellia galactanivorans adenosine deaminase YP_004735229.1 934943 D 63186 CDS YP_004735230.1 340616777 10977473 936059..936739 1 NC_015844.1 Ribulose-phosphate 3-epimerase converts D-ribulose 5-phosphate into D-xylulose 5-phosphate in Pentose phosphate pathway; Adopts a a TIM barrel fold; Localized in the cytoplasm; High confidence in function and specificity; Ribulose-phosphate 3-epimerase 936739 rpeA 10977473 rpeA Zobellia galactanivorans Ribulose-phosphate 3-epimerase YP_004735230.1 936059 D 63186 CDS YP_004735231.1 340616778 10978490 936718..937698 1 NC_015844.1 The pyridine nucleotide-disulphide reductases (PNDR) are thioredoxin reductase-like protein with a active site that is a redox-active disulfide bond. It uses the FAD to shuttle reducing equivalents from NAD(P)H to a Cys residue that is usually a part of a redox-active disulphide bridge. In a second step, the reduced disulphide reduces the substrate; Localized in the cytoplasm; Family membership; pyridine nucleotide-disulfide oxidoreductase 937698 10978490 zobellia_774 Zobellia galactanivorans pyridine nucleotide-disulfide oxidoreductase YP_004735231.1 936718 D 63186 CDS YP_004735232.1 340616779 10977306 937799..938293 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 938293 10977306 zobellia_775 Zobellia galactanivorans hypothetical protein YP_004735232.1 937799 D 63186 CDS YP_004735233.1 340616780 10977307 938304..940292 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two transmembrane segments and one N-terminal tetratrico peptide motif (TPR); Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 940292 10977307 zobellia_776 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004735233.1 938304 D 63186 CDS YP_004735234.1 340616781 10977308 940282..940926 1 NC_015844.1 Response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA- binding activity (here, a LuxR-type HTH domain) that acts as transcriptional regulator; Family membership; two-component system-response regulator 940926 10977308 zobellia_777 Zobellia galactanivorans two-component system-response regulator YP_004735234.1 940282 D 63186 CDS YP_004735235.1 340616782 10977309 complement(940927..941436) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 941436 10977309 zobellia_778 Zobellia galactanivorans membrane protein YP_004735235.1 940927 R 63186 CDS YP_004735236.1 340616783 10977310 complement(941459..943840) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (29-114) and the Plug module (130-226) acting as a channel gate; The signal peptide is cleaved between the residues 24 and 25; Family membership; TonB-dependent Receptor 943840 10977310 zobellia_779 Zobellia galactanivorans TonB-dependent Receptor YP_004735236.1 941459 R 63186 CDS YP_004735237.1 340616784 10977311 complement(943975..945972) 1 NC_015844.1 ZiaA is a P-type ATPase responsible for zinc efflux using ATP hydrolysis for energy. ZiaA controls zinc homeostasis. Belongs to the cation transport P-type ATPase family. Features six transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; Zinc-transporting P-type ATPase 945972 ziaA 10977311 ziaA Zobellia galactanivorans Zinc-transporting P-type ATPase YP_004735237.1 943975 R 63186 CDS YP_004735238.1 340616785 10978794 complement(946101..946586) 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 946586 10978794 zobellia_781 Zobellia galactanivorans membrane protein YP_004735238.1 946101 R 63186 CDS YP_004735239.1 340616786 10977313 complement(946714..947073) 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 947073 10977313 zobellia_782 Zobellia galactanivorans membrane protein YP_004735239.1 946714 R 63186 CDS YP_004735240.1 340616787 10977314 complement(947136..948314) 1 NC_015844.1 Protein belonging to the DUF1624 family; Contains eight transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 948314 10977314 zobellia_783 Zobellia galactanivorans membrane protein YP_004735240.1 947136 R 63186 CDS YP_004735241.1 340616788 10977315 948689..949606 1 NC_015844.1 2-Dehydropantoate 2-reductase, also known as ketopantoate reductase, catalyzes the NADPH-dependent reduction of ketopantoate to pantoate on the pantothenate (vitamin B5) biosynthetic pathway. Localized in the cytoplasm.; High confidence in function and specificity; 2-dehydropantoate 2-reductase 949606 panE 10977315 panE Zobellia galactanivorans 2-dehydropantoate 2-reductase YP_004735241.1 948689 D 63186 CDS YP_004735242.1 340616789 10978300 949615..949956 1 NC_015844.1 Protein containing three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 949956 10978300 zobellia_785 Zobellia galactanivorans hypothetical protein YP_004735242.1 949615 D 63186 CDS YP_004735243.1 340616790 10977316 950125..951087 1 NC_015844.1 tRNA-dihydrouridine synthase A catalyzes the reduction of the 5,6-double bond of a uridine residue, resulting in the formation of dihydrouridine. This modified base is found in the D-loop of most tRNAs. This enzyme uses FAD as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; tRNA-dihydrouridine synthase A 951087 dusA 10977316 dusA Zobellia galactanivorans tRNA-dihydrouridine synthase A YP_004735243.1 950125 D 63186 CDS YP_004735244.1 340616791 10977770 complement(951246..951569) 1 NC_015844.1 Protein that contains three transmembrane segments; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 951569 10977770 zobellia_787 Zobellia galactanivorans hypothetical protein YP_004735244.1 951246 R 63186 CDS YP_004735245.1 340616792 10974058 complement(951895..952341) 1 NC_015844.1 Conserved protein of unknown function Belongs to the GatB/YQeY family; Localized in the cytoplasm; hypothetical protein 952341 10974058 zobellia_789 Zobellia galactanivorans hypothetical protein YP_004735245.1 951895 R 63186 CDS YP_004735246.1 340616793 10977318 complement(952439..954400) 1 NC_015844.1 FtsZ is the polymer-forming protein of bacterial cell division. It is part of a dynamic ring on the inner surface of the cytoplasmic membrane, in the middle of the dividing cell that is required for constriction of cell envelope to yield two daughter cells. The formation of the ring is the signal for septation to begin. The ring serves as a scaffold for the recruitment of the ten or so membrane and cytoplasmic proteins required for cell division and that is disassembled when septation is completed. Binds to and hydrolyzes GTP; Localized in the cytoplasm; High confidence in function and specificity; cell division protein FtsZ 954400 ftsZ 10977318 ftsZ Zobellia galactanivorans cell division protein FtsZ YP_004735246.1 952439 R 63186 CDS YP_004735247.1 340616794 10977855 complement(954439..955776) 1 NC_015844.1 This protein may be a component of the septum where it may interact with ftsZ. May be involved in anomalous filament growth; The FtsA protein contains two structurally related actin-like ATPase domains; Localized in the cytoplasm; High confidence in function and specificity; cell division protein FtsA 955776 ftsA 10977855 ftsA Zobellia galactanivorans cell division protein FtsA YP_004735247.1 954439 R 63186 CDS YP_004735248.1 340616795 10977846 complement(955780..956499) 1 NC_015844.1 This hypothetical protein could be the FtsQ protein involved in septum formation. Could interact with ftsZ, ftsA, and penicillin binding protein 3. The function of FtsQ is unknown; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein; putative cell division protein ftsQ 956499 ftsQ 10977846 ftsQ Zobellia galactanivorans putative cell division protein ftsQ YP_004735248.1 955780 R 63186 CDS YP_004735249.1 340616796 10977851 complement(956489..957862) 1 NC_015844.1 UDP-N-acetylmuramate-L-alanine ligase is an enzyme involved in the biosynthesis of peptidoglycan which catalyzes the ATP-dependent ligation of L-alanine and UDP-N-acetylmuramic acid to form UDP-N-acetylmuramyl-L-alanine; Contains a N-terminal transmembrane segment; Belongs to the MurCDEF family; Localized in the cytoplasmic membrane; High confidence in function and specificity; UDP-N-acetylmuramate-L-alanine ligase 957862 murC 10977851 murC Zobellia galactanivorans UDP-N-acetylmuramate-L-alanine ligase YP_004735249.1 956489 R 63186 CDS YP_004735250.1 340616797 10978201 complement(957862..958965) 1 NC_015844.1 MurG is involved in the peptidoglycan biosynthesis. It catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II). Belongs to the family 28 of the glycosyltransferases. Localized in the cytoplasmic membrane.; High confidence in function and specificity; UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, family GT28 958965 murG 10978201 murG Zobellia galactanivorans UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, family GT28 YP_004735250.1 957862 R 63186 CDS YP_004735251.1 340616798 10978206 complement(958952..960151) 1 NC_015844.1 FtsW is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division; Contains ten transmembrane segments; Belongs to the ftsW/rodA/spoVE family; Localized in the cytoplasmic membrane; High confidence in function and specificity; cell division protein ftsW 960151 ftsW 10978206 ftsW Zobellia galactanivorans cell division protein ftsW YP_004735251.1 958952 R 63186 CDS YP_004735252.1 340616799 10977852 complement(960164..961498) 1 NC_015844.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase is an enzyme involved in the biosynthesis of peptidoglycan which catalyzes the addition of glutamic acid to the nucleotide precursor UDP-N-acetylmuramoylalanine; Belongs to the MurCDEF family; Localized in the cytoplasm; High confidence in function and specificity; UDP-N-acetylmuramoylalanine-D-glutamate ligase 961498 murD 10977852 murD Zobellia galactanivorans UDP-N-acetylmuramoylalanine-D-glutamate ligase YP_004735252.1 960164 R 63186 CDS YP_004735253.1 340616800 10978202 complement(961500..962720) 1 NC_015844.1 Phospho-N-acetylmuramoyl-pentapeptide-transferase is the enzyme responsible for the formation of the first lipid intermediate of the cell wall peptidoglycan synthesis. It catalyzes the formation of undecaprenyl-pyrophosphoryl-N-acetylmuramoyl-pentapeptide from UDP-MurNAc-pentapeptide and undecaprenyl-phosphate., Contains ten transmembrane segmlents. Belongs to family 4 of glycosyl transferases (GT4); Localized in the cytoplasmic membrane; High confidence in function and specificity; phospho-N-acetylmuramoyl-pentapeptide- transferase 962720 mraY 10978202 mraY Zobellia galactanivorans phospho-N-acetylmuramoyl-pentapeptide- transferase YP_004735253.1 961500 R 63186 CDS YP_004735254.1 340616801 10978176 complement(962760..964214) 1 NC_015844.1 UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase is an enzyme involved in the biosynthesis of peptidoglycan which catalyzes the addition of diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoylalanyl-D-glutamate. This enzyme is specific of Gram-negative bacteria ; Belongs to the MurCDEF family; Localized in the cytoplasm; High confidence in function and specificity; UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase 964214 murE 10978176 murE Zobellia galactanivorans UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase YP_004735254.1 962760 R 63186 CDS YP_004735255.1 340616802 10978203 complement(964220..966226) 1 NC_015844.1 Enzyme essential for the formation of a septum of the murein sacculus. Synthetizes the cross-linked peptidoglycan from the lipid intermediates; Contains in its N-terminal half part a transmembrane segment and an penicillin insensitive transglycosylase domain (formation of linear glycan strands). In its C-terminal half part, a penicillin- sensitive transpeptidase domain (cross-linking of the peptide subunits) and a PASTA domain that binds the beta-lactam stem are present; Belongs to the family 51 of glycosyl transferases (GT51); Except for the cytoplasmic membrane anchor region, The bulk of the molecule protrudes into the periplasmic space, where it acts on murein; High confidence in function and specificity; peptidoglycan synthetase 966226 ftsI 10978203 ftsI Zobellia galactanivorans peptidoglycan synthetase YP_004735255.1 964220 R 63186 CDS YP_004735256.1 340616803 10977848 complement(966226..966555) 1 NC_015844.1 Hypothetical protein that could be FtsL involved in coupling of cell division and peptidoglycan physiology; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein; putative cell division protein FtsL 966555 ftsL 10977848 ftsL Zobellia galactanivorans putative cell division protein FtsL YP_004735256.1 966226 R 63186 CDS YP_004735257.1 340616804 10977850 complement(966584..967483) 1 NC_015844.1 Enzyme involved in the murein biosynthesis and that exhibits a S-adenosyl-dependent methyltransferase activity on membrane-located substrates; Localized in the cytoplasm; High confidence in function and specificity; S-adenosyl-methyltransferase MraW 967483 mraW 10977850 mraW Zobellia galactanivorans S-adenosyl-methyltransferase MraW YP_004735257.1 966584 R 63186 CDS YP_004735258.1 340616805 10978175 complement(967473..967946) 1 NC_015844.1 Protein that could play a role in cell-wall biosynthesis and/or cell division. However, to date, there has been no clear functional assignment provided for MraZ protein. MraZ is a homooctamer or homododecamer to forms a ring; Localized in the cytoplasm; Function unclear; protein MraZ 967946 mraZ 10978175 mraZ Zobellia galactanivorans protein MraZ YP_004735258.1 967473 R 63186 CDS YP_004735259.1 340616806 10978177 968201..968965 1 NC_015844.1 The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Localized in the cytoplasm; Function unclear; alpha/beta hydrolase-fold protein 968965 10978177 zobellia_803 Zobellia galactanivorans alpha/beta hydrolase-fold protein YP_004735259.1 968201 D 63186 CDS YP_004735260.1 340616807 10977321 968998..969615 1 NC_015844.1 The EngB protein is a GTPase necessary for normal cell division and for the maintenance of normal septation. Depletion of this protein leads to a severe reduction in growth rate and to extensive filamentation, with a block beyond the stage of segregation. Essential for bacteria survival; Belongs to the EngB family; Localized in the cytoplasm; High confidence in function and specificity; GTP-binding protein EngB 969615 engB 10977321 engB Zobellia galactanivorans GTP-binding protein EngB YP_004735260.1 968998 D 63186 CDS YP_004735261.1 340616808 10977780 complement(969612..969992) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 969992 10977780 zobellia_805 Zobellia galactanivorans hypothetical protein YP_004735261.1 969612 R 63186 CDS YP_004735262.1 340616809 10977322 970040..970783 1 NC_015844.1 CcrA hydrolyzes carbapenem and cephamycin compounds; Binds 2 zinc ions as cofactors; Belongs to the class B of the beta-lactamases family; Contains a putative lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; High confidence in function and specificity; metallo-beta-lactamase 970783 ccrA 10977322 ccrA Zobellia galactanivorans metallo-beta-lactamase YP_004735262.1 970040 D 63186 CDS YP_004735263.1 340616810 10977638 970813..971526 1 NC_015844.1 Conserved protein highly Localized in the cytoplasm; Family membership; Pirin-like protein 971526 10977638 zobellia_807 Zobellia galactanivorans Pirin-like protein YP_004735263.1 970813 D 63186 CDS YP_004735264.1 340616811 10977323 complement(971535..971867) 1 NC_015844.1 GldC is not absolutely required for gliding motility but enhances colony spreading; Localized in the cytoplasm; Function unclear; gliding motility protein 971867 gldC 10977323 gldC Zobellia galactanivorans gliding motility protein YP_004735264.1 971535 R 63186 CDS YP_004735265.1 340616813 10977900 complement(971869..972828) 1 NC_015844.1 Lipoprotein involved in the gliding motility; It is possible that GldB interacts with, or is involved in production of polysaccharides or glycoproteins; Signal peptide cleaved between the residues 16 and 17; Putatively localized in the cytoplasmic membrane; Function unclear; gliding motility membrane lipoprotein 972828 gldB 10977900 gldB Zobellia galactanivorans gliding motility membrane lipoprotein YP_004735265.1 971869 R 63186 CDS YP_004735266.1 340616812 10977899 972809..973711 1 NC_015844.1 NH(3)-dependent NAD(+) synthetase catalyzes the last step in the biosynthesis of nicotinamide adenine dinucleotid, the transformation of deamido-NAD into NAD by a two-step reaction. This enzyme consists of a tight homodimer with alpha/beta subunit topology. Each monomer binds one ATP as a cofactor. Localized in the cytoplasm.; High confidence in function and specificity; NH(3)-dependent NAD(+) synthetase 973711 nadE 10977899 nadE Zobellia galactanivorans NH(3)-dependent NAD(+) synthetase YP_004735266.1 972809 D 63186 CDS YP_004735267.1 340616814 10978222 973883..974512 1 NC_015844.1 Response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA- binding activity (here a LuxR-type HTH domain) that acts as transcriptional regulator; Family membership; two-component system-response regulator 974512 10978222 zobellia_811 Zobellia galactanivorans two-component system-response regulator YP_004735267.1 973883 D 63186 CDS YP_004735268.1 340616816 10977324 complement(974600..976579) 1 NC_015844.1 DNA primase is a DNA-directed RNA polymerase that synthesizes small RNA primers for the Okazaki fragments in lagging strand DNA synthesis of the replication fork during chromosomal DNA replication. It can also prime the leading strand at the Ori site. The enzyme is monomeric and interacts with the DNA helicase (DnaB), single- stranded DNA binding protein (SSB) and DNA polymerase III holoenzyme forming a complex called the primosome; Binds one zinc ion as a cofactor; Localized in the cytoplasm; High confidence in function and specificity; DNA primase 976579 dnaG 10977324 dnaG Zobellia galactanivorans DNA primase YP_004735268.1 974600 R 63186 CDS YP_004735269.1 340616815 10977752 976563..976721 1 NC_015844.1 Hypothetical protein; hypothetical protein 976721 10977752 zobellia_812 Zobellia galactanivorans hypothetical protein YP_004735269.1 976563 D 63186 CDS YP_004735270.1 340616817 10977325 976751..977176 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 977176 10977325 zobellia_814 Zobellia galactanivorans membrane protein YP_004735270.1 976751 D 63186 CDS YP_004735271.1 340616818 10977326 977290..977853 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 977853 10977326 zobellia_815 Zobellia galactanivorans hypothetical protein YP_004735271.1 977290 D 63186 CDS YP_004735272.1 340616819 10977327 complement(977955..978932) 1 NC_015844.1 Octaprenyl diphosphate synthase supplies octaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones, ubiquinone and menaquinone; Localized in the cytoplasm; High confidence in function and specificity; Octaprenyl diphosphate synthase 978932 ispB 10977327 ispB Zobellia galactanivorans Octaprenyl diphosphate synthase YP_004735272.1 977955 R 63186 CDS YP_004735273.1 340616820 10978045 complement(979112..980152) 1 NC_015844.1 Conserved protein belonging to the Radical SAM protein family. These enzymes catalyze diverse reactions, including unusual methylations, isomerization, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation. Evidence exists that these proteins generate a radical species by reductive cleavage of S:-adenosylmethionine (SAM) through an unusual Fe-S center; Localized in the cytoplasm; Family membership; Radical SAM family protein 980152 10978045 zobellia_817 Zobellia galactanivorans Radical SAM family protein YP_004735273.1 979112 R 63186 CDS YP_004735274.1 340616821 10977328 complement(980236..981285) 1 NC_015844.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine to give epoxyqueuosine. Queuosine is a hypermodified nucleoside usually found at the first position of the anticodon of asparagine, aspartate, histidine, and tyrosine tRNAs. Localized in the cytoplasm.; High confidence in function and specificity; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 981285 queA 10977328 queA Zobellia galactanivorans S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_004735274.1 980236 R 63186 CDS YP_004735275.1 340616822 10978428 complement(981457..982686) 1 NC_015844.1 3-Phosphoshikimate 1-carboxyvinyltransferase, also known as 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase, is involved in the shikimate pathway (the sixth step). EPSP synthase catalyzes the reaction: phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. It is inhibited by the potent herbicide glyphosate. Localized in the cytoplasm.; High confidence in function and specificity; 3-phosphoshikimate 1-carboxyvinyltransferase 982686 aroA 10978428 aroA Zobellia galactanivorans 3-phosphoshikimate 1-carboxyvinyltransferase YP_004735275.1 981457 R 63186 CDS YP_004735276.1 340616823 10977543 complement(982789..983115) 1 NC_015844.1 Conserved protein belonging to the MazG nucleotide pyrophosphohydrolase family; Localized in the cytoplasm; Family membership; nucleotide pyrophosphohydrolase family protein 983115 10977543 zobellia_820 Zobellia galactanivorans nucleotide pyrophosphohydrolase family protein YP_004735276.1 982789 R 63186 CDS YP_004735277.1 340616824 10977330 complement(983081..985141) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 985141 10977330 zobellia_821 Zobellia galactanivorans periplasmic protein YP_004735277.1 983081 R 63186 CDS YP_004735278.1 340616825 10977331 complement(985171..987081) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 987081 10977331 zobellia_822 Zobellia galactanivorans periplasmic protein YP_004735278.1 985171 R 63186 CDS YP_004735279.1 340616826 10977332 complement(987161..987613) 1 NC_015844.1 D-Tyrosyl-tRNA(Tyr) deacylase hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine. Can also cleave D-aspartyl-tRNA(Asp) and D-tryptophanyl-tRNA(Trp). It forms a homodimer; Localized in the cytoplasm; High confidence in function and specificity; D-Tyrosyl-tRNA(Tyr) deacylase 987613 dtd 10977332 dtd Zobellia galactanivorans D-Tyrosyl-tRNA(Tyr) deacylase YP_004735279.1 987161 R 63186 CDS YP_004735280.1 340616827 10977768 complement(987657..988625) 1 NC_015844.1 EngC, has been shown to cleave GTP, remain bound to GDP, and acts as an unusual circularly permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover. It is essential to cell growth. In vitro, EngC interacted strongly with the 30S ribosomal subunit. EngC could participates to a guanine nucleotide- dependent interaction with the ribosome and would be a novel factor in ribosome function; Localized in the cytoplasm; High confidence in function and specificity; GTPase engC 988625 engC 10977768 engC Zobellia galactanivorans GTPase engC YP_004735280.1 987657 R 63186 CDS YP_004735281.1 340616828 10977781 988787..989230 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 989230 10977781 zobellia_825 Zobellia galactanivorans periplasmic protein YP_004735281.1 988787 D 63186 CDS YP_004735282.1 340616829 10977333 complement(989294..990376) 1 NC_015844.1 Bifunctional enzyme including 3-deoxy-7-phosphoheptulonate synthase (DAHP synthase) in N-terminus and chorismate mutase in C-terminus. DAHP synthase catalyzes the first step in the common pathway leading to the biosynthesis of aromatic compounds, the stereospecific condensation of phosphoenolpyruvate and D-erythrose-4-phosphate giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). Chorismate mutase catalyzes the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis. Localized in the cytoplasm.; High confidence in function and specificity; 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase 990376 aroGH 10977333 aroGH Zobellia galactanivorans 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase YP_004735282.1 989294 R 63186 CDS YP_004735283.1 340616830 10977548 complement(990376..991236) 1 NC_015844.1 Prephenate dehydrogenase is involved in tyrosine biosynthesis. It catalyzes the reaction: prephenate + NAD+ = 4-hydroxyphenylpyruvate + CO2 + NADH. It uses NAD as a cofactor. Localized in the cytoplam.; High confidence in function and specificity; prephenate dehydrogenase 991236 tyrA 10977548 tyrA Zobellia galactanivorans prephenate dehydrogenase YP_004735283.1 990376 R 63186 CDS YP_004735284.1 340616831 10978717 complement(991260..992405) 1 NC_015844.1 Aminotransferases use the Pyridoxal phosphate as cofactor bound by covalent linkage to a lysine residue; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; Specificity unclear; aminotransferase 992405 10978717 zobellia_828 Zobellia galactanivorans aminotransferase YP_004735284.1 991260 R 63186 CDS YP_004735285.1 340616832 10977334 complement(992402..993229) 1 NC_015844.1 Prephenate dehydratase catalyzes the decarboxylation of prephenate to phenylpyruvate. PheA is involved in L-phenylalanine biosynthesis. It features a C- terminal ACT domain. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. Localized in the cytoplasm.; High confidence in function and specificity; prephenate dehydratase 993229 pheA 10977334 pheA Zobellia galactanivorans prephenate dehydratase YP_004735285.1 992402 R 63186 CDS YP_004735286.1 340616833 10978340 993669..994565 1 NC_015844.1 GldA is the nucleotide-binding domain of the permease GldF. GldA (ABC ATPase) and GldF (ABC membrane) constitute an ABC transporter involved either in the exportation of exopolysaccharides essential to gliding motility or could function to export protein components of the gliding machinery to the periplasm or cell surface; Localized in the cytopolasm; Family membership; gliding motility ABC transporter ATPase 994565 gldA 10978340 gldA Zobellia galactanivorans gliding motility ABC transporter ATPase YP_004735286.1 993669 D 63186 CDS YP_004735287.1 340616834 10977898 complement(994623..995090) 1 NC_015844.1 Signal peptide cleaved between the residues 22 and 23; Contains two transmembrane segments; Probably localized in the cytoplasmic membrane; hypothetical protein 995090 10977898 zobellia_831 Zobellia galactanivorans hypothetical protein YP_004735287.1 994623 R 63186 CDS YP_004735288.1 340616835 10977336 complement(995192..996280) 1 NC_015844.1 Serine peptidase belonging to the family S12, which includes D-Ala-D-Ala carboxypeptidase B and aminopeptidase DmpB. The active site residues Ser and Lys form the catalytic dyad and are found in the motif Ser-Xaa-Thr-Lys. Localized in the cytoplasm.; Specificity unclear; serine peptidase 996280 10977336 zobellia_832 Zobellia galactanivorans serine peptidase YP_004735288.1 995192 R 63186 CDS YP_004735289.1 340616836 10977337 complement(996367..997128) 1 NC_015844.1 Liporoteine with a signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 997128 10977337 zobellia_833 Zobellia galactanivorans lipoprotein YP_004735289.1 996367 R 63186 CDS YP_004735290.1 340616837 10977338 complement(997203..998297) 1 NC_015844.1 Signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; hypothetical protein 998297 10977338 zobellia_834 Zobellia galactanivorans hypothetical protein YP_004735290.1 997203 R 63186 CDS YP_004735291.1 340616838 10977339 complement(998370..999323) 1 NC_015844.1 The 5,10-methylenetetrahydrofolate reductase is involved in the Methionine biosynthesis reducing the 5,10-Methylenetetrahydrofolate to 5-methyltetrahydrofolate. The 5-methyltetrahydrofolate is utilized by methionine synthase to convert homocysteine to methionine; The enzyme is a FAD-containing flavoprotein homotetramer; Belongs to the methylenetetrahydrofolate reductase family; Localized in the cytoplasm; High confidence in function and specificity; 5,10-methylenetetrahydrofolate reductase 999323 metF 10977339 metF Zobellia galactanivorans 5,10-methylenetetrahydrofolate reductase YP_004735291.1 998370 R 63186 CDS YP_004735292.1 340616839 10978150 complement(999516..1002254) 1 NC_015844.1 Methionine synthase or 5-methyltetrahydrofolate-homocysteine S-methyltransferase catalyzes the transfer of a methyl group from methylcob(III)alamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate (CH3-H4folate); Modular enzyme composed of a N-terminal pterin-binding module that binds the CH3-H4 folate, a central B12-binding module that binds the cofactor and a C-terminal AdoMet activation module that binds S-adenosyl-L-methionine essential for the reductive activation of the enzyme; Uses the cobalamin (vitamin B12) and zinc ion as cofactors; Localized in the cytoplasm; High confidence in function and specificity; methionine synthase, cobalamin-binding module 1002254 metH 10978150 metH Zobellia galactanivorans methionine synthase, cobalamin-binding module YP_004735292.1 999516 R 63186 CDS YP_004735293.1 340616840 10978152 complement(1002299..1003300) 1 NC_015844.1 Methionine synthase or 5-methyltetrahydrofolate-homocysteine S-methyltransferase catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate; L-homocysteine is bound via the zinc atom; Uses the cobalamin (vitamin B12) and zinc as cofactors; This sequence corresponds to the homocysteine-binding domain (Hcy-binding domain) only; Belongs to the vitamin-B12 dependent methionine synthase family; Localized in the cytoplasm; High confidence in function and specificity; methionine synthase, homocysteine-binding module 1003300 metH 10978152 metH Zobellia galactanivorans methionine synthase, homocysteine-binding module YP_004735293.1 1002299 R 63186 CDS YP_004735294.1 340616841 10978153 complement(1003348..1003623) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1003623 10978153 zobellia_838 Zobellia galactanivorans hypothetical protein YP_004735294.1 1003348 R 63186 CDS YP_004735295.1 340616842 10977340 complement(1003669..1004730) 1 NC_015844.1 The active site of this enzyme is a redox-active disulfide bond. TrxB uses the FAD to shuttle reducing equivalents from NAD(P)H to a Cys residue that is usually a part of a redox-active disulphide bridge. In a second step, the reduced disulphide reduces the substrate; Acts as an homodimer and binds one FAD molecule per subunit; Belongs to the class 2 of the pyridine nucleotide- disulphide reductases (PNDR); Localized in the cytoplasm; High confidence in function and specificity; thioredoxin reductase 1004730 trxB3 10977340 trxB3 Zobellia galactanivorans thioredoxin reductase YP_004735295.1 1003669 R 63186 CDS YP_004735296.1 340616843 10978711 complement(1004733..1005530) 1 NC_015844.1 This enzyme catalyzes two sequential methylation reactions, forming precorrin-1 and precorrin-2 by methylations at C-2 and C-7 of uroporphyrinogen III respectively; It is the first enzyme specific to the cobalamin (vitamin B12) pathway and precorrin-2 is a common intermediate in the biosynthesis of corrinoids such as vitamin B12, siroheme and coenzyme F430; Belongs to the precorrin methyltransferase family; Localized in the cytoplasm; High confidence in function and specificity; uroporphyrinogen-III C-methyltransferase 1005530 cobA1 10978711 cobA1 Zobellia galactanivorans uroporphyrinogen-III C-methyltransferase YP_004735296.1 1004733 R 63186 CDS YP_004735297.1 340616844 10977665 complement(1005533..1007623) 1 NC_015844.1 [ferredoxin]; Sulfite reductase catalyses the six-electron reduction reactions of sulfite to sulfide; Contains a Fe(4)S(4) cluster coupled to a siroheme through a cysteine bridge; Would contains a C-terminal HEPN domain of unknown function; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family; Localized in the cytoplasm; High confidence in function and specificity; sulfite reductase 1007623 sirA 10977665 sirA Zobellia galactanivorans sulfite reductase YP_004735297.1 1005533 R 63186 CDS YP_004735298.1 340616845 10978597 complement(1007746..1008996) 1 NC_015844.1 The sulfate adenylyltransferase (ATP sulfurylase) catalyses the activation of sulfate with ATP to produce 5'-phosphosulfate (APS), coupled by GTP hydrolysis. The sulfate adenylyltransferase subunit 1 may be the GTPase subunit, regulating ATP sulfurylase activity; ATP sulfurylase is a heterodimer composed of cysD, the smaller subunit, and cysN; Belongs to the GTP-binding elongation factor family; Localized in the cytoplasm; High confidence in function and specificity; sulfate adenylyltransferase subunit 1 1008996 cysN 10978597 cysN Zobellia galactanivorans sulfate adenylyltransferase subunit 1 YP_004735298.1 1007746 R 63186 CDS YP_004735299.1 340616846 10977708 complement(1009054..1009956) 1 NC_015844.1 The sulfate adenylyltransferase (ATP sulfurylase) catalyses the activation of sulfate with ATP to produce 5'-phosphosulfate (APS), coupled by GTP hydrolysis. ATP sulfurylase is a heterodimer composed of cysD, the smaller subunit, and cysN; Belongs to the PAPS reductase family; Localized in the cytoplasm; High confidence in function and specificity; sulfate adenylyltransferase subunit 2 1009956 cysD 10977708 cysD Zobellia galactanivorans sulfate adenylyltransferase subunit 2 YP_004735299.1 1009054 R 63186 CDS YP_004735300.1 340616847 10977700 complement(1010023..1010646) 1 NC_015844.1 The 3'-phosphoadenosine 5'-phosphosulfate (PAPS) reductase called also PAPS sulfotransferase catalyses the reduction of activated sulfate into sulfite; The enzyme uses thioredoxin as an electron donor for the reduction of PAPS to phospho-adenosine-phosphate (PAP); Belongs to the PAPS reductase family; Localized in the cytoplasm; High confidence in function and specificity; phosphoadenosine phosphosulfate reductase 1010646 cysH 10977700 cysH Zobellia galactanivorans phosphoadenosine phosphosulfate reductase YP_004735300.1 1010023 R 63186 CDS YP_004735301.1 340616848 10977702 complement(1010653..1010916) 1 NC_015844.1 Contains a C-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1010916 10977702 zobellia_845 Zobellia galactanivorans membrane protein YP_004735301.1 1010653 R 63186 CDS YP_004735302.1 340616849 10977341 complement(1011096..1011506) 1 NC_015844.1 The transcriptional regulators with the Rrf2-type HTH domain control a variety of operons that encode iron-sulfur-containing proteins as well as other proteins involved in electron transport. Other rrf2-type HTH proteins are repressors of genes involved in nitrite or iron metabolism; The C-terminal part of the rrf2-type HTH domain contains 3 conserved cysteine residues that may bind an Fe-S cluster; Contains a DNA-binding, winged helix-turn-helix (wHTH) domain; Localized in the cytoplasm; Family membership; Rrf2-type transcriptional regulator 1011506 10977341 zobellia_846 Zobellia galactanivorans Rrf2-type transcriptional regulator YP_004735302.1 1011096 R 63186 CDS YP_004735303.1 340616850 10977342 1011715..1012371 1 NC_015844.1 Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1012371 10977342 zobellia_847 Zobellia galactanivorans membrane protein YP_004735303.1 1011715 D 63186 CDS YP_004735304.1 340616851 10977343 1012508..1013089 1 NC_015844.1 The Crp/Fnr-type transcriptional regulators complexe with cyclic AMP and bind to operator sites near the promoter with a C-terminal HTH domain to regulate the transcription of several catabolite-sensitive operons; They predominantly act as transcription activators, but can also be important repressors, and respond to diverse intracellular and exogenous signals; Localized in the cytoplasm; Family membership; Crp/Fnr-type transcriptional regulator 1013089 10977343 zobellia_848 Zobellia galactanivorans Crp/Fnr-type transcriptional regulator YP_004735304.1 1012508 D 63186 CDS YP_004735305.1 340616852 10977344 1013175..1014065 1 NC_015844.1 Conserved protein belonging to the zinc-dependent beta-lactamase superfamily. This superfamily contains various metallo-hydrolases including beta-lactamases, but also glyoxylases and arylsulfatases. The active site is characterized by several conserved histidines binding the catalytic zinc ions. The enzymes can bind one or two zinc ions; Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Family membership; metallo-beta-lactamase superfamily protein 1014065 10977344 zobellia_849 Zobellia galactanivorans metallo-beta-lactamase superfamily protein YP_004735305.1 1013175 D 63186 CDS YP_004735306.1 340616853 10977345 1014059..1014526 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the cytoplasmic membrane; Conserved hypothetical protein; lipoprotein 1014526 10977345 zobellia_850 Zobellia galactanivorans lipoprotein YP_004735306.1 1014059 D 63186 CDS YP_004735307.1 340616854 10977346 1014824..1017571 1 NC_015844.1 This protein is modular with a N-terminal domain belonging to the family 9 of the polysaccharide lyases (23-622) and a C-terminal conserved domain of unknown function (661-915). The PL9 domain adopts a right handed parallel beta-helix fold. In contrast to other proteins from the PL9 family, a conserved domain of unknown function is inserted within loops of the beta-helix core (97-271). Such domain insertion in a beta-helix has been observed in the family GH82. Features a signal peptide cleaved between residues 23 and 24. Localized in the periplasm.; Specificity unclear; polysaccharide lyase 1017571 10977346 zobellia_851 Zobellia galactanivorans polysaccharide lyase YP_004735307.1 1014824 D 63186 CDS YP_004735308.1 340616855 10977347 1017568..1018278 1 NC_015844.1 This conserved protein contains a C-terminal type-III fibronectin (FN3) domain. Structures of individual FN3 domains have revealed a conserved beta sandwich fold also found in bacterial glycosyde hydrolases and other proteins; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Function unclear; fibronectin type-III repeat-containing protein 1018278 10977347 zobellia_852 Zobellia galactanivorans fibronectin type-III repeat-containing protein YP_004735308.1 1017568 D 63186 CDS YP_004735309.1 340616856 10977348 complement(1018352..1019521) 1 NC_015844.1 Enzyme involved in the methionine biosynthesis, second step, transforms the O-succinylhomoserine into homocysteine; Uses a pyridoxal phosphate group as cofactor, attached to a lysine residue located in the central section of the enzyme; Localized in the cytoplasm; High confidence in function and specificity; O-succinylhomoserine sulfhydrylase 1019521 metZ 10977348 metZ Zobellia galactanivorans O-succinylhomoserine sulfhydrylase YP_004735309.1 1018352 R 63186 CDS YP_004735310.1 340616857 10978157 complement(1019550..1022942) 1 NC_015844.1 This enzyme is a modular protein with a homoserine O-acetyltransferase module (N-terminal) that catalyses the homoserine acetylation and belongs to the alpha/beta hydrolase fold family, an aspartate kinase module (central) that catalyzes the phosphorylation of aspartate and belongs to the amino acid kinase family and, in C- terminal part, a homoserine dehydrogenase module that catalyzes the NAD-dependent reduction of aspartate beta- semialdehyde into homoserine. This module is composed of a substrate-binding domain (Homoserine dehydrogenase family) and a NAD-binding domain (Rossman fold); MetX features also central regulatory ACT domain; Involved in L-Lysine, L-threonine and L-methionine biosynthesis pathways; Localized in the cytoplasm; High confidence in function and specificity; homoserine O-acetyltransferase / aspartokinase / homoserine dehydrogenase 1022942 metX 10978157 metX Zobellia galactanivorans homoserine O-acetyltransferase / aspartokinase / homoserine dehydrogenase YP_004735310.1 1019550 R 63186 CDS YP_004735311.1 340616858 10978155 complement(1023011..1024285) 1 NC_015844.1 Transforms O-acetylhomoserine into L-methionine. Also reacts with other thiols and H2S, producing homocysteine or thioethers; Uses a pyridoxal phosphate group as cofactor, attached to a lysine residue located in the central section of the enzyme; Localized in the cytoplasm; High confidence in function and specificity; Cys/Met metabolism pyridoxal-phosphate-dependent protein 1024285 metY 10978155 metY Zobellia galactanivorans Cys/Met metabolism pyridoxal-phosphate-dependent protein YP_004735311.1 1023011 R 63186 CDS YP_004735312.1 340616859 10978156 complement(1024600..1025856) 1 NC_015844.1 S-adenosylmethionine synthetase catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. It forms a homotetramer and binds 2 divalent cations (Mg2+ or Co2+) and 1 potassium ion by subunit; Localized in the cytoplasm; High confidence in function and specificity; S-adenosylmethionine synthetase 1025856 metK 10978156 metK Zobellia galactanivorans S-adenosylmethionine synthetase YP_004735312.1 1024600 R 63186 CDS YP_004735313.1 340616860 10978154 complement(1026125..1028803) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (22-105) and the Plug module acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Specificity unclear; TonB-dependent Receptor 1028803 10978154 zobellia_857 Zobellia galactanivorans TonB-dependent Receptor YP_004735313.1 1026125 R 63186 CDS YP_004735314.1 340616861 10977349 complement(1028858..1029721) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1029721 10977349 zobellia_858 Zobellia galactanivorans periplasmic protein YP_004735314.1 1028858 R 63186 CDS YP_004735315.1 340616862 10977350 1029830..1030531 1 NC_015844.1 Deoxyguanosine kinase plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism. Localized in the cytoplasm.; High confidence in function and specificity; deoxyguanosine kinase 1030531 dgkA1 10977350 dgkA1 Zobellia galactanivorans deoxyguanosine kinase YP_004735315.1 1029830 D 63186 CDS YP_004735316.1 340616863 10977735 complement(1030539..1031546) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1031546 10977735 zobellia_860 Zobellia galactanivorans hypothetical protein YP_004735316.1 1030539 R 63186 CDS YP_004735317.1 340616864 10977351 1031732..1032436 1 NC_015844.1 TonB is an energy-transducer for TonB-dependent receptors of Gram-negative bacteria. Energy flows from the cytoplasmic membrane into the outer membrane via a complex consisting of TonB, ExbB and ExbD proteins which are anchored in the cytoplasmic membrane. TonB interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates; Belongs to the TonB family; Anchored in the cytoplasmic membrane; High confidence in function and specificity; TonB protein 1032436 tonB1 10977351 tonB1 Zobellia galactanivorans TonB protein YP_004735317.1 1031732 D 63186 CDS YP_004735318.1 340616865 10978670 complement(1032495..1034870) 1 NC_015844.1 Pyrophosphate-energized proton pump generates a proton motive force; it probably catalyzes a fully reversible reaction, thus being able to synthesize pyrophosphate when the proton motive force is sufficient. It controls intracellular pyrophosphate (PPi) levels and confer a favorable poise on otherwise thermodynamically unfavorable pyrophosphorylytic biosynthetic reactions. It forms a homodimer. Activated by magnesium and potassium ions. Features fifteen transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; pyrophosphate-energized proton pump 1034870 hpaA 10978670 hpaA Zobellia galactanivorans pyrophosphate-energized proton pump YP_004735318.1 1032495 R 63186 CDS YP_004735319.1 340616866 10977990 complement(1034979..1035506) 1 NC_015844.1 Inorganic pyrophosphatase is responsible for the hydrolysis of pyrophosphate (PPi) which is formed principally as the product of the many biosynthetic reactions that utilize ATP. It controls intracellular PPi levels and confer a favorable poise on otherwise thermodynamically unfavorable pyrophosphorylytic biosynthetic reactions. It forms a homohexamer and binds 4 magnesium ions per subunit. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product. Localized in the cytoplasm.; High confidence in function and specificity; inorganic pyrophosphatase 1035506 ppa 10977990 ppa Zobellia galactanivorans inorganic pyrophosphatase YP_004735319.1 1034979 R 63186 CDS YP_004735320.1 340616867 10978368 complement(1035714..1038215) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Could be localized in the outer membrane; Conserved hypothetical protein; membrane protein 1038215 10978368 zobellia_864 Zobellia galactanivorans membrane protein YP_004735320.1 1035714 R 63186 CDS YP_004735321.1 340616868 10977352 complement(1038430..1039407) 1 NC_015844.1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 component is a homodimer of an alpha and a beta subunits. PdhB is the subunit beta and displays a modular architecture. In N-terminus, it features a lipoyl attachment domain, which has a conserved lysine residue that covalently binds lipoic acid. The C-terminal domain belongs to the transketolase family and binds thiamine pyrophosphate as prosthetic group; Localized in the cytoplasm.; High confidence in function and specificity; pyruvate dehydrogenase, E1 component subunit beta 1039407 pdhB 10977352 pdhB Zobellia galactanivorans pyruvate dehydrogenase, E1 component subunit beta YP_004735321.1 1038430 R 63186 CDS YP_004735322.1 340616869 10978316 1039582..1040322 1 NC_015844.1 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various dehydrogenases. In Bacteria, ETFs are produced under specific growth conditions, receiving electrons only from the oxidation of specific substrates. ETFs are heterodimeric proteins composed of an alpha and beta subunit, and contain an FAD cofactor and an AMP molecule. EtfB codes the beta subunit that binds the AMP molecule; Localized in the cytoplasm; High confidence in function and specificity; electron transfer flavoprotein subunit beta 1040322 etfB 10978316 etfB Zobellia galactanivorans electron transfer flavoprotein subunit beta YP_004735322.1 1039582 D 63186 CDS YP_004735323.1 340616870 10977788 1040410..1041378 1 NC_015844.1 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various dehydrogenases. In Bacteria, ETFs are produced under specific growth conditions, receiving electrons only from the oxidation of specific substrates. ETFs are heterodimeric proteins composed of an alpha and beta subunit, and contain an FAD cofactor and an AMP molecule. EtfA codes the alpha subunit that participate, with the alpha subunit, to the binding of the FAD molecule; Localized in the cytoplasm; High confidence in function and specificity; electron transfer flavoprotein subunit alpha 1041378 etfA 10977788 etfA Zobellia galactanivorans electron transfer flavoprotein subunit alpha YP_004735323.1 1040410 D 63186 CDS YP_004735324.1 340616871 10977787 1041415..1042092 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF151 family. Also displays a C-terminal UVR domain (~35 residues). The UVR domain has been first described in UvrB and UvrC, enzymes involved in DNA repair. This domain in UvrB can interact with the homologous domain in UvrC throughout a putative coiled coil structure; Localized in the cytoplasm; Conserved hypothetical protein; UVR domain-containing protein 1042092 10977787 zobellia_868 Zobellia galactanivorans UVR domain-containing protein YP_004735324.1 1041415 D 63186 CDS YP_004735325.1 340616872 10977353 1042110..1043558 1 NC_015844.1 Except guanosine and deoxyguanosine, NupC transports nucleosides with a high affinity by a proton motive force; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; nucleoside permease NupC 1043558 nupC 10977353 nupC Zobellia galactanivorans nucleoside permease NupC YP_004735325.1 1042110 D 63186 CDS YP_004735326.1 340616873 10978280 1043666..1044490 1 NC_015844.1 Thymidylate synthase catalyzes the reductive methylation of dUMP to dTMP with concomitant conversion of 5,10-methylenetetrahydrofolate to dihydrofolate. This provides the sole de novo pathway for production of dTMP and is the only enzyme in folate metabolism in which the 5, 10-methylenetetrahydrofolate is oxidized during one- carbon transfer. It forms a homodimer and is localized in the cytoplasm.; High confidence in function and specificity; thymidylate synthase 1044490 thyA 10978280 thyA Zobellia galactanivorans thymidylate synthase YP_004735326.1 1043666 D 63186 CDS YP_004735327.1 340616874 10978661 1044561..1045733 1 NC_015844.1 Contains a domain found in some eukaryotic and prokaryotic protein kinase and in eukaryotic proteins required for post-translational sulphatase modification; Putatively localized in the outer membrane; Localized in the cytoplasm; hypothetical protein 1045733 10978661 zobellia_871 Zobellia galactanivorans hypothetical protein YP_004735327.1 1044561 D 63186 CDS YP_004735328.1 340616875 10977355 1045777..1046748 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1046748 10977355 zobellia_872 Zobellia galactanivorans hypothetical protein YP_004735328.1 1045777 D 63186 CDS YP_004735329.1 340616876 10977356 1046816..1047097 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF427 family. Localized in the cytoplasm.; Family membership; hypothetical protein 1047097 10977356 zobellia_873 Zobellia galactanivorans hypothetical protein YP_004735329.1 1046816 D 63186 CDS YP_004735330.1 340616877 10977357 complement(1047195..1047494) 1 NC_015844.1 Carbohydrate binding module belonging to the family CBM48. CBM48s usually bind to glycogen and are associated to GH13 modules or to AMP-activated protein kinases. The exact function of this isolated CBM48 is unknown. Localized in the cytoplasm.; Specificity unclear; carbohydrate binding protein 1047494 10977357 zobellia_874 Zobellia galactanivorans carbohydrate binding protein YP_004735330.1 1047195 R 63186 CDS YP_004735331.1 340616878 10977358 complement(1047662..1048750) 1 NC_015844.1 Isopenicillin N epimerase catalyzes the reversible isomerization between isopenicillin N and penicillin N. Uses pyridoxal phosphate as a cofactor. Belongs to class V of the aminotransferases. Localized in the cytoplasm.; High confidence in function and specificity; isopenicillin N epimerase 1048750 cefD 10977358 cefD Zobellia galactanivorans isopenicillin N epimerase YP_004735331.1 1047662 R 63186 CDS YP_004735332.1 340616879 10977643 1048809..1049198 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1049198 10977643 zobellia_876 Zobellia galactanivorans membrane protein YP_004735332.1 1048809 D 63186 CDS YP_004735333.1 340616880 10977359 1049195..1049692 1 NC_015844.1 Dihydrofolate reductase catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, an essential step in de novo synthesis both of glycine and of purines and deoxythymidine phosphate (the precursors of DNA synthesis). It is also important in the conversion of deoxyuridine monophosphate to deoxythymidine monophosphate. Localized in the cytoplasm.; High confidence in function and specificity; dihydrofolate reductase 1049692 dfrA 10977359 dfrA Zobellia galactanivorans dihydrofolate reductase YP_004735333.1 1049195 D 63186 CDS YP_004735334.1 340616881 10977733 complement(1049681..1050469) 1 NC_015844.1 Glutamate racemase, which interconverts L-glutamate into D-glutamate, is required for the biosynthesis of peptidoglycan and some peptide-based antibiotics such as gramicidin S. Two conserved cysteines are expected to play a role in catalytic activity by acting as bases in proton abstraction from the substrate. Localized in the cytoplasm.; High confidence in function and specificity; glutamate racemase 1050469 murI 10977733 murI Zobellia galactanivorans glutamate racemase YP_004735334.1 1049681 R 63186 CDS YP_004735335.1 340616882 10978207 complement(1050482..1052143) 1 NC_015844.1 Cda is a calcium-dependent ATPase. Vanadate strongly inhibits its activity; Belongs to the alkaline phosphatase clan, type I phosphodiesterase family; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; High confidence in function and specificity; calcium-dependent ATPase 1052143 cda1 10978207 cda1 Zobellia galactanivorans calcium-dependent ATPase YP_004735335.1 1050482 R 63186 CDS YP_004735336.1 340616883 10977639 1052293..1052994 1 NC_015844.1 ABC (ATP-binding cassette) transporters are responsible for translocation of a variety of compounds across biological membranes; Probably, this protein is the membrane component of an ABC importer; Contains a DUF140 domain and five transmembrane segments; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 1052994 10977639 zobellia_880 Zobellia galactanivorans ABC transporter permease YP_004735336.1 1052293 D 63186 CDS YP_004735337.1 340616884 10977361 1052994..1053761 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasmic membrane as a peripheral membrane protein; Family membership; ABC transporter ATPase 1053761 10977361 zobellia_881 Zobellia galactanivorans ABC transporter ATPase YP_004735337.1 1052994 D 63186 CDS YP_004735338.1 340616885 10977362 complement(1053798..1055270) 1 NC_015844.1 Protein belonging to the DUF389 family; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1055270 10977362 zobellia_882 Zobellia galactanivorans membrane protein YP_004735338.1 1053798 R 63186 CDS YP_004735339.1 340616886 10977363 complement(1055280..1056362) 1 NC_015844.1 Mannose-1-phosphate guanylyltransferase, also known as GDP-mannose pyrophosphorylase, is Involved in the biosynthesis of exopolysaccharides. It catalyzes the reaction: GDP + alpha-D-mannose 1-phosphate = phosphate + GDP-mannose. Localized in the cytoplasm.; High confidence in function and specificity; mannose-1-phosphate guanylyltransferase 1056362 manC 10977363 manC Zobellia galactanivorans mannose-1-phosphate guanylyltransferase YP_004735339.1 1055280 R 63186 CDS YP_004735340.1 340616887 10978123 complement(1056459..1057070) 1 NC_015844.1 Conserved protein belonging to a family including SprT, a regulator of bolA gene in stationary phase. Displays a conserved HExxH motif reminiscent of the metallopeptidase zinc binding signature. Localized in the cytoplasm.; Family membership; SprT family protein 1057070 10978123 zobellia_884 Zobellia galactanivorans SprT family protein YP_004735340.1 1056459 R 63186 CDS YP_004735341.1 340616888 10977364 complement(1057168..1057848) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 1057848 10977364 zobellia_885 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004735341.1 1057168 R 63186 CDS YP_004735342.1 340616889 10977365 complement(1057848..1058900) 1 NC_015844.1 Family M28 contains aminopeptidases and carboxypeptidases with two co-catalytic zinc ions. Each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the outer and/or cytoplasmic membrane; Specificity unclear; metallopeptidase 1058900 10977365 zobellia_886 Zobellia galactanivorans metallopeptidase YP_004735342.1 1057848 R 63186 CDS YP_004735343.1 340616890 10977366 complement(1058989..1060617) 1 NC_015844.1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2, linking glycolysis to the tricarboxylic acid cycle. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). PdhC is the E2 component and is a dihydrolipoyllysine-residue acetyltransferase. It catalyzes the reaction: Acetyl-CoA + enzyme 6-N-(dihydrolipoyl)lysine = CoA + enzyme 6-N-(S-acetyldihydrolipoyl)lysine. PdhC features two N-terminal lipoyl-binding domains, a central E3- binding domain, and a C-terminal catalytic domain belonging to the 2-oxoacid dehydrogenases acyltransferase family. Each lipoyl-binding domain has a conserved lysine residue that covalently binds lipoic acid. PdhC forms a 24- polypeptide structural core with octahedral symmetry. Localized in the cytoplasm.; High confidence in function and specificity; dihydrolipoyllysine-residue acetyltransferase, PdH complex E2 component 1060617 pdhC 10977366 pdhC Zobellia galactanivorans dihydrolipoyllysine-residue acetyltransferase, PdH complex E2 component YP_004735343.1 1058989 R 63186 CDS YP_004735344.1 340616891 10978317 complement(1060626..1061621) 1 NC_015844.1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2, linking glycolysis to the tricarboxylic acid cycle. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 component is a homodimer of an alpha and a beta subunits. PdhB is the subunit beta and displays a modular architecture. In N-terminus, it features a lipoyl attachment domain, which has a conserved lysine residue that covalently binds lipoic acid. The C-terminal domain belongs to the transketolase family and binds thiamine pyrophosphate as a cofactor. Localized in the cytoplasm.; High confidence in function and specificity; pyruvate dehydrogenase, E1 component subunit alpha 1061621 pdhA 10978317 pdhA Zobellia galactanivorans pyruvate dehydrogenase, E1 component subunit alpha YP_004735344.1 1060626 R 63186 CDS YP_004735345.1 340616892 10978315 complement(1061774..1062256) 1 NC_015844.1 Cytidine deaminase scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. It catalyzes the reaction: cytidine + H2O = uridine + NH3. It forms a homotetramer and binds 1 zinc ion per subunit. Localized in the cytoplasm.; High confidence in function and specificity; cytidine deaminase 1062256 cdd 10978315 cdd Zobellia galactanivorans cytidine deaminase YP_004735345.1 1061774 R 63186 CDS YP_004735346.1 340616893 10977641 complement(1062332..1063483) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1063483 10977641 zobellia_890 Zobellia galactanivorans periplasmic protein YP_004735346.1 1062332 R 63186 CDS YP_004735347.1 340616894 10977368 1063946..1065613 1 NC_015844.1 Lipoprotein involved in the gliding motility that contains an unknown function domain found in some eukaryotic and prokaryotic protein and in eukaryotic proteins required for post-translational modification of sulfatase; Signal peptide cleaved between the residues 23 and 24; Putatively localized in the outer membrane; Function unclear; gliding motility membrane lipoprotein 1065613 gldJ 10977368 gldJ Zobellia galactanivorans gliding motility membrane lipoprotein YP_004735347.1 1063946 D 63186 CDS YP_004735348.1 340616895 10977907 1065652..1066959 1 NC_015844.1 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (MurF) is an enzyme involved in the final step of the biosynthesis of peptidoglycan. MurF catalyzes the addition of D-alanyl-D-alanine to the nucleotide precursor UDP-N- acetylmuramoyl-L-alanyl-D-glutamyl-meso-2, 6-diaminoheptanedioate; Belongs to the MurCDEF family; Localized in the cytoplasm; High confidence in function and specificity; UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase 1066959 murF1 10977907 murF1 Zobellia galactanivorans UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase YP_004735348.1 1065652 D 63186 CDS YP_004735349.1 340616896 10978204 complement(1067024..1067848) 1 NC_015844.1 Conserved membrane protein belonging to the Small-conductance mechanosensitive channel family; Contains five transmembrane helices; Localized in the cytoplasmic membrane; Family membership; MscS family protein 1067848 10978204 zobellia_893 Zobellia galactanivorans MscS family protein YP_004735349.1 1067024 R 63186 CDS YP_004735350.1 340616897 10977369 complement(1067867..1068052) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1068052 10977369 zobellia_894 Zobellia galactanivorans hypothetical protein YP_004735350.1 1067867 R 63186 CDS YP_004735351.1 340616899 10977370 complement(1068057..1068602) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 1068602 10977370 zobellia_896 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004735351.1 1068057 R 63186 CDS YP_004735352.1 340616898 10977372 1068568..1068951 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 1068951 10977372 zobellia_895 Zobellia galactanivorans hypothetical protein YP_004735352.1 1068568 D 63186 CDS YP_004735353.1 340616900 10977371 1069299..1069505 1 NC_015844.1 Hypothetical protein; hypothetical protein 1069505 10977371 zobellia_897 Zobellia galactanivorans hypothetical protein YP_004735353.1 1069299 D 63186 CDS YP_004735354.1 340616901 10974059 1070186..1071556 1 NC_015844.1 Contains four transmembrane helices in the N-terminal region and a central motif reminiscent of the Planctomycete cytochrome C motif; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1071556 10974059 zobellia_899 Zobellia galactanivorans membrane protein YP_004735354.1 1070186 D 63186 CDS YP_004735355.1 340616902 10977374 complement(1071803..1072066) 1 NC_015844.1 Protein that consists of an GIY-YIG catalytic domain of unknown function found in the amino terminal region of excinuclease abc subunit c (region 1 of UvrC) and in few other nucleases from bacteria and bacteriophages; Localized in the cytoplasm; Function unclear; endonuclease 1072066 10977374 zobellia_900 Zobellia galactanivorans endonuclease YP_004735355.1 1071803 R 63186 CDS YP_004735356.1 340616903 10974021 complement(1072244..1073428) 1 NC_015844.1 Bifunctional enzyme that converts the folates to polyglutamate derivatives; Folylpolyglutamate synthase (EC 6.3.2.17) is responsible for the ATP-dependent addition of a polyglutamate tail to tetrahydrofolate. Dihydrofolate synthase (EC 6.3.2.12) is reponsible for attaching the first glutamate residue to dihydropteroate to form dihydrofolate. The combined activity leads to the formation of the coenzyme polyglutamated tetrahydropteroate (H4PteGlu(n)), i.e. various tetrahydrofolates (H4folate); Localized in the cytoplasm; High confidence in function and specificity; folylpolyglutamate synthase / dihydrofolate synthase 1073428 folC 10974021 folC Zobellia galactanivorans folylpolyglutamate synthase / dihydrofolate synthase YP_004735356.1 1072244 R 63186 CDS YP_004735357.1 340616904 10977836 complement(1073452..1074393) 1 NC_015844.1 TolA, involved in the tonB-independent uptake of proteins, interacts with the TolQ and TolR, cytoplasmic membrane proteins and with the Pal protein (OprL) in the outer membrane. The transport is energized by the proton motive force. The Tol-Pal complex is required for maintaining outer membrane integrity, the transport (uptake) filamentous DNA and is the conduct for bacteriophages; TolA is anchored to the cytoplasmic membrane by a single transmembrane spanning segment near the N-terminus, leaving most of the protein exposed to the periplasm; High confidence in function and specificity; protein TolA 1074393 tolA 10977836 tolA Zobellia galactanivorans protein TolA YP_004735357.1 1073452 R 63186 CDS YP_004735358.1 340616905 10978667 complement(1074393..1074779) 1 NC_015844.1 TolR, involved in the tonB-independent uptake of biopolymers, forms a complex with the proteins TolQ. This complex energizes TolA from the potential energy of the ion electrochemical gradient. TolA energized, interacts with the outer membrane protein Pal (OprL). The Tol-Pal complex is required for maintaining outer membrane integrity, the transport (uptake) filamentous DNA and is the conduct for bacteriophages; Contains a N-terminal transmembrane helix; Belongs to the exbD/tolR family; Localized in the cytoplasmic membrane; High confidence in function and specificity; protein TolR 1074779 tolR 10978667 tolR Zobellia galactanivorans protein TolR YP_004735358.1 1074393 R 63186 CDS YP_004735359.1 340616906 10978669 complement(1074790..1075482) 1 NC_015844.1 TolQ, involved in the tonB-independent uptake of biopolymers, forms a complex with the proteins TolR. This complex energizes TolA from the potential energy of the ion electrochemical gradient. TolA energized, interacts with the outer membrane protein Pal (OprL). The Tol-Pal complex is required for maintaining outer membrane integrity, the transport (uptake) filamentous DNA and is the conduct for bacteriophages; Contains three transmembrane helices; Belongs to the exbB/tolQ family; Localized in the cytoplasmic membrane; High confidence in function and specificity; protein TolQ 1075482 tolQ 10978669 tolQ Zobellia galactanivorans protein TolQ YP_004735359.1 1074790 R 63186 CDS YP_004735360.1 340616907 10978668 complement(1075534..1076901) 1 NC_015844.1 Conserved protein belonging to the citrate transporter family, which includes two characterized citrate/proton symporters from Bacillus subtilis. Its exact specificity is unknown. Features eleven transmembrane helices. Localized in the cytoplasmic membrane.; Family membership; citrate transporter family protein 1076901 10978668 zobellia_906 Zobellia galactanivorans citrate transporter family protein YP_004735360.1 1075534 R 63186 CDS YP_004735361.1 340616908 10977377 complement(1076915..1078147) 1 NC_015844.1 NAD(P)-dependent dehydrogenase distantly related to glutamate dehydrogenase; Localized in the cytoplasm; Specificity unclear; NAD(P)-dependent oxidoreductase 1078147 10977377 zobellia_907 Zobellia galactanivorans NAD(P)-dependent oxidoreductase YP_004735361.1 1076915 R 63186 CDS YP_004735362.1 340616909 10977378 1078432..1079574 1 NC_015844.1 Butyryl-CoA dehydrogenase converts the Butanoyl-CoA to 2-butenoyl-CoA. It uses electron transfer flavoprotein (FAD) as its electron acceptor; Localized in the cytoplasm; High confidence in function and specificity; Butyryl-CoA dehydrogenase 1079574 bcdA 10977378 bcdA Zobellia galactanivorans Butyryl-CoA dehydrogenase YP_004735362.1 1078432 D 63186 CDS YP_004735363.1 340616910 10977589 1079891..1084399 1 NC_015844.1 Glutamate synthase is a key enzyme in the early stages of the assimilation of ammonia. It is a complex iron-sulfur flavoprotein catalyzing the reductive transfer of the amido nitrogen from L-glutamine to 2-oxoglutarate to form two molecules of L-glutamate via intramolecular channelling of ammonia from the amidotransferase domain to the FMN-binding domain. Glutamate synthase forms an aggregate of 4 catalytic active heterodimers, consisting of a large and a small subunit (GltB). GltA binds as cofactors a 3Fe-4S cluster, a FAD and a FMN. Localized in the cytoplasm.; High confidence in function and specificity; glutamate synthase [NADPH] large chain 1084399 gltA 10977589 gltA Zobellia galactanivorans glutamate synthase [NADPH] large chain YP_004735363.1 1079891 D 63186 CDS YP_004735364.1 340616911 10977930 1084409..1085875 1 NC_015844.1 Glutamate synthase is a key enzyme in the early stages of the assimilation of ammonia. It is a complex iron-sulfur flavoprotein catalyzing the reductive transfer of the amido nitrogen from L-glutamine to 2-oxoglutarate to form two molecules of L-glutamate via intramolecular channelling of ammonia from the amidotransferase domain to the FMN-binding domain. Glutamate synthase forms an aggregate of 4 catalytic active heterodimers, consisting of a large (GltA) and a small subunit . GltB binds NADP(H) as a cofactor. Localized in the cytoplasm.; High confidence in function and specificity; glutamate synthase [NADPH] small chain 1085875 gltB 10977930 gltB Zobellia galactanivorans glutamate synthase [NADPH] small chain YP_004735364.1 1084409 D 63186 CDS YP_004735365.1 340616912 10977931 1085928..1086842 1 NC_015844.1 Protein containing two tandem domains belonging to the DUF6 family. Predicted as a transporter; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1086842 10977931 zobellia_911 Zobellia galactanivorans membrane protein YP_004735365.1 1085928 D 63186 CDS YP_004735366.1 340616913 10977379 complement(1086930..1088477) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 28; Signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Family membership; sulfatase 1088477 10977379 zobellia_912 Zobellia galactanivorans sulfatase YP_004735366.1 1086930 R 63186 CDS YP_004735367.1 340616914 10977380 complement(1088539..1089975) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 23; Signal peptide of Lipoprotein cleaved between the residues 16 and 17; Localized in the outer membrane; Family membership; sulfatase 1089975 10977380 zobellia_913 Zobellia galactanivorans sulfatase YP_004735367.1 1088539 R 63186 CDS YP_004735368.1 340616915 10977381 complement(1090188..1091639) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 20 and 21; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 1091639 10977381 zobellia_914 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004735368.1 1090188 R 63186 CDS YP_004735369.1 340616916 10977382 complement(1091657..1095112) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain (67-119)) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (142-216), and a Plug module (232-356) acting as the channel gate; The signal peptide is cleaved between the residue 21 and 22; Family membership; TonB-dependent transducer 1095112 10977382 zobellia_915 Zobellia galactanivorans TonB-dependent transducer YP_004735369.1 1091657 R 63186 CDS YP_004735370.1 340616917 10977383 complement(1095245..1096381) 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 1096381 10977383 zobellia_916 Zobellia galactanivorans anti-sigma factor YP_004735370.1 1095245 R 63186 CDS YP_004735371.1 340616918 10977384 1096658..1097197 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 1097197 10977384 zobellia_917 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004735371.1 1096658 D 63186 CDS YP_004735372.1 340616919 10977385 complement(1097243..1098364) 1 NC_015844.1 Conserved protein containing a putative lipoprotein signal peptide cleaved between the residues 15 and 16; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 1098364 10977385 zobellia_918 Zobellia galactanivorans membrane protein YP_004735372.1 1097243 R 63186 CDS YP_004735373.1 340616920 10977386 complement(1098391..1099236) 1 NC_015844.1 D-Tagatose 3-epimerase catalyzes the epimerization of various ketohexoses at the C3 position. It folds into a Xylose isomerase-like TIM barrel. Localized in the cytoplasm.; High confidence in function and specificity; D-tagatose 3-epimerase 1099236 10977386 zobellia_919 Zobellia galactanivorans D-tagatose 3-epimerase YP_004735373.1 1098391 R 63186 CDS YP_004735374.1 340616921 10977387 complement(1099445..1100326) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 1100326 10977387 zobellia_920 Zobellia galactanivorans AraC family transcriptional regulator YP_004735374.1 1099445 R 63186 CDS YP_004735375.1 340616922 10977388 1100664..1103834 1 NC_015844.1 Large conserved protein containing a C-terminal cytochrome c. Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 14 and 15; Localized in the outer membrane; Family membership; cytochrome c-containing protein 1103834 10977388 zobellia_921 Zobellia galactanivorans cytochrome c-containing protein YP_004735375.1 1100664 D 63186 CDS YP_004735376.1 340616923 10977389 1104394..1107564 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (57-131) and the Plug module (147-263) acting as a channel gate; The signal peptide is cleaved between the residues 29 and 30; Family membership; TonB-dependent Receptor 1107564 10977389 zobellia_922 Zobellia galactanivorans TonB-dependent Receptor YP_004735376.1 1104394 D 63186 CDS YP_004735377.1 340616924 10977390 1107586..1109094 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 1109094 10977390 zobellia_923 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004735377.1 1107586 D 63186 CDS YP_004735378.1 340616925 10974016 1115299..1115508 1 NC_015844.1 Hypothetical protein; hypothetical protein 1115508 10974016 zobellia_929 Zobellia galactanivorans hypothetical protein YP_004735378.1 1115299 D 63186 CDS YP_004735379.1 340616926 10977392 complement(1115572..1117572) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1117572 10977392 zobellia_930 Zobellia galactanivorans periplasmic protein YP_004735379.1 1115572 R 63186 CDS YP_004735380.1 340616927 10977394 1117822..1118427 1 NC_015844.1 Ribonuclease HII is involved in the degradation of the ribonucleotide moiety on RNA-DNA hybrid molecules carrying out endonucleolytic cleavage to 5'-phospo-monoester. Binds 1 divalent metal ion (manganese or magnesium) in the absence of substrate. May bind a second metal ion after substrate binding. Localized in the cytoplasm.; High confidence in function and specificity; ribonuclease HII 1118427 rnhB 10977394 rnhB Zobellia galactanivorans ribonuclease HII YP_004735380.1 1117822 D 63186 CDS YP_004735381.1 340616928 10978482 1118656..1119999 1 NC_015844.1 This conserved protein contains a N-terminal glucanase-like beta-sandwich domain of unknown function and a C-terminal OmpA-like domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Signal peptide cleaved between the residues 26 and 27; Localized in the outer membrane and/or periplasm; Family membership; OmpA-like periplasmic protein 1119999 10978482 zobellia_932 Zobellia galactanivorans OmpA-like periplasmic protein YP_004735381.1 1118656 D 63186 CDS YP_004735382.1 340616929 10977395 1120012..1120710 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1120710 10977395 zobellia_933 Zobellia galactanivorans periplasmic protein YP_004735382.1 1120012 D 63186 CDS YP_004735383.1 340616930 10977396 1120745..1122109 1 NC_015844.1 Serine peptidase contains a catalytic triad in the order Asp, His and Ser in the sequence. Its structure consists of three layers with a seven-stranded beta sheet sandwiched between two layers of helices; Belongs to the family S8 of peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the cytoplasmic membrane; Specificity unclear; serine peptidase 1122109 10977396 zobellia_934 Zobellia galactanivorans serine peptidase YP_004735383.1 1120745 D 63186 CDS YP_004735384.1 340616931 10977397 1122149..1125052 1 NC_015844.1 Conserved protein containing three N-terminal tetratrico peptide repeats (TPRs) and a C-terminal conserved domain of unknown function. TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Contains a C-terminal transmembrane helix; Localized in the cytoplasmic membrane; Function unclear; hypothetical protein 1125052 10977397 zobellia_935 Zobellia galactanivorans hypothetical protein YP_004735384.1 1122149 D 63186 CDS YP_004735385.1 340616932 10977398 complement(1125055..1125792) 1 NC_015844.1 Contains one central transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1125792 10977398 zobellia_936 Zobellia galactanivorans membrane protein YP_004735385.1 1125055 R 63186 CDS YP_004735386.1 340616933 10977399 complement(1125795..1126364) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released. They alter the specificity of promoter recognition. This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors.; Family membership; RNA polymerase ECF-type sigma factor 1126364 10977399 zobellia_937 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004735386.1 1125795 R 63186 CDS YP_004735387.1 340616934 10977400 complement(1126484..1126702) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1126702 10977400 zobellia_938 Zobellia galactanivorans hypothetical protein YP_004735387.1 1126484 R 63186 CDS YP_004735388.1 340616935 10977401 1126843..1127151 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22, Probably localized in the outer membrane; hypothetical protein 1127151 10977401 zobellia_939 Zobellia galactanivorans hypothetical protein YP_004735388.1 1126843 D 63186 CDS YP_004735389.1 340616936 10977402 1127601..1128341 1 NC_015844.1 Conserved hypothetical protein including an N-terminal region rich in glycine, reminiscent of the collagen triple helix repeats (GxxG). Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 23 and 24; Localized in the outer membrane; hypothetical protein 1128341 10977402 zobellia_940 Zobellia galactanivorans hypothetical protein YP_004735389.1 1127601 D 63186 CDS YP_004735390.1 340616937 10977403 1128418..1128549 1 NC_015844.1 Hypothetical protein; hypothetical protein 1128549 10977403 zobellia_941 Zobellia galactanivorans hypothetical protein YP_004735390.1 1128418 D 63186 CDS YP_004735391.1 340616938 10977404 complement(1128760..1129056) 1 NC_015844.1 Contains a transmembrane helix; Putatively localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1129056 10977404 zobellia_942 Zobellia galactanivorans hypothetical protein YP_004735391.1 1128760 R 63186 CDS YP_004735392.1 340616939 10977405 1129062..1130117 1 NC_015844.1 Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 1130117 10977405 zobellia_943 Zobellia galactanivorans hypothetical protein YP_004735392.1 1129062 D 63186 CDS YP_004735393.1 340616940 10977406 1130200..1131222 1 NC_015844.1 This conserved protein displays Kelch repeats. The kelch motif forms a beta sheet and several of these sheets associate to form a beta propeller structure, as demonstrated for galactose oxidase. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the cytoplasmic membrane; Function unclear; Kelch repeat-containing protein 1131222 10977406 zobellia_944 Zobellia galactanivorans Kelch repeat-containing protein YP_004735393.1 1130200 D 63186 CDS YP_004735394.1 340616941 10977407 1131591..1132145 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 1132145 10977407 zobellia_945 Zobellia galactanivorans hypothetical protein YP_004735394.1 1131591 D 63186 CDS YP_004735395.1 340616942 10977408 1132248..1132859 1 NC_015844.1 Conserved hypothetical protein including an N-terminal region rich in glycine, reminiscent of the collagen triple helix repeats (GxxG); Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; hypothetical protein 1132859 10977408 zobellia_946 Zobellia galactanivorans hypothetical protein YP_004735395.1 1132248 D 63186 CDS YP_004735396.1 340616943 10977409 1132975..1133622 1 NC_015844.1 Conserved hypothetical protein including an N-terminal region rich in glycine, reminiscent of the collagen triple helix repeats (GxxG); Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; hypothetical protein 1133622 10977409 zobellia_947 Zobellia galactanivorans hypothetical protein YP_004735396.1 1132975 D 63186 CDS YP_004735397.1 340616944 10977410 1133736..1133912 1 NC_015844.1 Hypothetical protein; hypothetical protein 1133912 10977410 zobellia_948 Zobellia galactanivorans hypothetical protein YP_004735397.1 1133736 D 63186 CDS YP_004735398.1 340616945 10977411 1134030..1134650 1 NC_015844.1 Conserved hypothetical protein including an N-terminal region rich in glycine, reminiscent of the collagen triple helix repeats (GxxG); Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; hypothetical protein 1134650 10977411 zobellia_949 Zobellia galactanivorans hypothetical protein YP_004735398.1 1134030 D 63186 CDS YP_004735399.1 340616946 10977412 complement(1134687..1135406) 1 NC_015844.1 Lipoyltransferase catalyzes the transfer of the endogenously synthesized lipoate to apoproteins, creating an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoate-dependent enzymes. Utilizes lipoyl-acyl-carrier-protein as a source of lipoyl groups, although octanoyl groups from octanoyl-ACP can also be transferred to the lipoyl domain of apoproteins. Localized in the cytoplasm.; High confidence in function and specificity; lipoyltransferase 1135406 lipB 10977412 lipB Zobellia galactanivorans lipoyltransferase YP_004735399.1 1134687 R 63186 CDS YP_004735400.1 340616947 10978094 complement(1135433..1136170) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1136170 10978094 zobellia_951 Zobellia galactanivorans lipoprotein YP_004735400.1 1135433 R 63186 CDS YP_004735401.1 340616948 10977414 1136202..1136360 1 NC_015844.1 Protein fragment found in hypothetical proteins from Flavobacteriaceae; Putatively localized in the cytoplasm; hypothetical protein 1136360 10977414 zobellia_952 Zobellia galactanivorans hypothetical protein YP_004735401.1 1136202 D 63186 CDS YP_004735402.1 340616949 10977415 1136557..1138245 1 NC_015844.1 Lysyl-tRNA synthetase catalyzes the attachment of L-lysine to the tRNA(Lys) in a highly specific two-step reaction. LysS is an homodimer and binds 3 magnesium ions per subunit; Belongs to the class II of the aminoacyl-tRNA synthetases; Localized in the cytoplasm; High confidence in function and specificity; Lysyl-tRNA synthetase 1138245 lysS 10977415 lysS Zobellia galactanivorans Lysyl-tRNA synthetase YP_004735402.1 1136557 D 63186 CDS YP_004735403.1 340616950 10978113 1138652..1141390 1 NC_015844.1 This protein has a modular architecture with a N-terminal cytochrome c, a central domain of unknown function (DUF1549) which includes a second cytochrome c and a C-terminal domain of unknown function (DUF1553). Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes. The two domains DUF1549 and DUF1553 are usually found in Planctomycetes. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Function unclear; cytochrome c-containing protein 1141390 10978113 zobellia_954 Zobellia galactanivorans cytochrome c-containing protein YP_004735403.1 1138652 D 63186 CDS YP_004735404.1 340616951 10977416 1141394..1142905 1 NC_015844.1 Conserved hypothetical protein (family DUF1501). Belongs to the alkaline-phosphatase clan. Features a twin-arginine signal peptide. Localized in the periplasm.; Family membership; hypothetical protein 1142905 10977416 zobellia_955 Zobellia galactanivorans hypothetical protein YP_004735404.1 1141394 D 63186 CDS YP_004735405.1 340616952 10977417 1142936..1143808 1 NC_015844.1 Conserved protein adopting a xylose-isomerase-like TIM barrel fold; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Conserved hypothetical protein; TIM-barrel fold protein 1143808 10977417 zobellia_956 Zobellia galactanivorans TIM-barrel fold protein YP_004735405.1 1142936 D 63186 CDS YP_004735406.1 340616953 10977418 1143818..1145209 1 NC_015844.1 Contains five transmembrane helices in the N-terminal region and a central motif reminiscent of the Planctomycetes cytochrome C motif; Localized in the cytoplasmic membrane.; Conserved hypothetical protein; membrane protein 1145209 10977418 zobellia_957 Zobellia galactanivorans membrane protein YP_004735406.1 1143818 D 63186 CDS YP_004735407.1 340616954 10977419 1145260..1146690 1 NC_015844.1 Sodium-dependent dicarboxylate transporter sdcS mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient. Features thirteen transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; sodium-dependent dicarboxylate transporter sdcS 1146690 sdcS 10977419 sdcS Zobellia galactanivorans sodium-dependent dicarboxylate transporter sdcS YP_004735407.1 1145260 D 63186 CDS YP_004735408.1 340616955 10978571 complement(1146775..1147182) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1147182 10978571 zobellia_959 Zobellia galactanivorans periplasmic protein YP_004735408.1 1146775 R 63186 CDS YP_004735409.1 340616956 10977420 1147674..1150169 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1150169 10977420 zobellia_960 Zobellia galactanivorans periplasmic protein YP_004735409.1 1147674 D 63186 CDS YP_004735410.1 340616957 10977421 1150882..1151325 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1151325 10977421 zobellia_961 Zobellia galactanivorans periplasmic protein YP_004735410.1 1150882 D 63186 CDS YP_004735411.1 340616958 10977422 1151463..1151957 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1151957 10977422 zobellia_962 Zobellia galactanivorans hypothetical protein YP_004735411.1 1151463 D 63186 CDS YP_004735412.1 340616959 10977423 complement(1152102..1153382) 1 NC_015844.1 Glutamate-1-semialdehyde 2,1-aminomutase or Glutamate-1-semialdehyde aminotransferase (GSA) is a isomerase that catalyses the intramolecular transfer of amino group from C4 to C5 yielding the conversion of L-glutamate-1-semialdehyde (or (S)-4-amino-5-oxopentanoate) to 5-aminolevulinate during the second step of porphyrin biosynthesis by the C5 pathway; Uses the Pyridoxal phosphate as cofactor linked to a conserved lysine residue; Belongs to the class-III pyridoxal-phosphate - dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity; glutamate-1-semialdehyde 2,1-aminomutase 1153382 hemL 10977423 hemL Zobellia galactanivorans glutamate-1-semialdehyde 2,1-aminomutase YP_004735412.1 1152102 R 63186 CDS YP_004735413.1 340616960 10977971 complement(1153383..1154240) 1 NC_015844.1 This enzyme, probably involved in peptidoglycan metabolism, is a modular protein with a N-terminal endo-beta-N-acetylglucosaminidase domain and a C-terminal LysM peptidoglycan-binding domain. Endo-beta-N-acetylglucosaminidase catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides. The catalytic module belongs to the family 73 of the glycoside hydrolases (GH73). LysM domains belongs to the family 50 of the carbohydrate binding modules (CBM50). Contains a putative lipoprotein signal peptide cleaved between the residues 17 and 18; Possibly localized in the outer membrane; Specificity unclear; endo-beta-N-acetylglucosaminidase 1154240 10977971 zobellia_964 Zobellia galactanivorans endo-beta-N-acetylglucosaminidase YP_004735413.1 1153383 R 63186 CDS YP_004735414.1 340616961 10977424 complement(1154237..1155148) 1 NC_015844.1 D-cysteine desulfhydrase catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine. Can also catalyze the degradation of 3-chloro-D-alanine. It uses pyridoxal phosphate as a cofactor. Localized in the cytoplasm.; High confidence in function and specificity; D-cysteine desulfhydrase 1155148 dcyD 10977424 dcyD Zobellia galactanivorans D-cysteine desulfhydrase YP_004735414.1 1154237 R 63186 CDS YP_004735415.1 340616962 10977723 complement(1155215..1155544) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1155544 10977723 zobellia_966 Zobellia galactanivorans hypothetical protein YP_004735415.1 1155215 R 63186 CDS YP_004735416.1 340616963 10977425 1155747..1155908 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 1155908 10977425 zobellia_967 Zobellia galactanivorans hypothetical protein YP_004735416.1 1155747 D 63186 CDS YP_004735417.1 340616964 10977426 1155987..1156544 1 NC_015844.1 Contains a signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1156544 10977426 zobellia_968 Zobellia galactanivorans periplasmic protein YP_004735417.1 1155987 D 63186 CDS YP_004735418.1 340616965 10977427 1156665..1158428 1 NC_015844.1 Phenylalanine 4-monooxygenase, also known as phenylalanine-4-hydroxylase, is involved in L-phenylalanine biodegradation. It catalyzes the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4a-hydroxytetrahydrobiopterin. It binds Fe(2+) ion as a cofactor. PhhA belongs to the biopterin-dependent aromatic amino acid hydroxylase family. Localized in the cytoplasm.; High confidence in function and specificity; phenylalanine 4-monooxygenase 1158428 phhA 10977427 phhA Zobellia galactanivorans phenylalanine 4-monooxygenase YP_004735418.1 1156665 D 63186 CDS YP_004735419.1 340616966 10978343 1158517..1159725 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 1159725 10978343 zobellia_970 Zobellia galactanivorans hypothetical protein YP_004735419.1 1158517 D 63186 CDS YP_004735420.1 340616967 10977429 complement(1159737..1160351) 1 NC_015844.1 Contains an uncleaved signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1160351 10977429 zobellia_971 Zobellia galactanivorans membrane protein YP_004735420.1 1159737 R 63186 CDS YP_004735421.1 340616968 10977430 complement(1160401..1161363) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1161363 10977430 zobellia_972 Zobellia galactanivorans hypothetical protein YP_004735421.1 1160401 R 63186 CDS YP_004735422.1 340616969 10977431 complement(1161432..1161737) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1161737 10977431 zobellia_973 Zobellia galactanivorans membrane protein YP_004735422.1 1161432 R 63186 CDS YP_004735423.1 340616970 10977432 complement(1161721..1161849) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1161849 10977432 zobellia_974 Zobellia galactanivorans hypothetical protein YP_004735423.1 1161721 R 63186 CDS YP_004735424.1 340616971 10977433 complement(1161949..1162503) 1 NC_015844.1 The Crp/Fnr-type transcriptional regulators complexe with cyclic AMP and bind to operator sites near the promoter with a C-terminal HTH domain to regulate the transcription of several catabolite-sensitive operons; They predominantly act as transcription activators, but can also be important repressors, and respond to diverse intracellular and exogenous signals; Localized in the cytoplasm; Family membership; Crp/Fnr-type transcriptional regulator 1162503 10977433 zobellia_975 Zobellia galactanivorans Crp/Fnr-type transcriptional regulator YP_004735424.1 1161949 R 63186 CDS YP_004735425.1 340616972 10977434 complement(1162602..1163276) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1163276 10977434 zobellia_976 Zobellia galactanivorans hypothetical protein YP_004735425.1 1162602 R 63186 CDS YP_004735426.1 340616973 10977435 complement(1163516..1166131) 1 NC_015844.1 Alanyl-tRNA synthetase catalyses the attachment of alanine to its cognate transfer RNA molecule in a highly specific two-step reaction. AlaS forms is a homotetramer and belongs to the class II of the aminoacyl-tRNA synthetases. Binds 1 zinc ion per subunit. Localized in the cytoplasm.; High confidence in function and specificity; alanyl-tRNa synthetase 1166131 alaS 10977435 alaS Zobellia galactanivorans alanyl-tRNa synthetase YP_004735426.1 1163516 R 63186 CDS YP_004735427.1 340616974 10977488 1166233..1167210 1 NC_015844.1 Peptidase family M23 mainly contains endopeptidases that lyze bacterial cell wall peptidoglycans. One catalytic zinc ion is bound per peptidase molecule. The cation ligands occur in the conserved motifs HXXXD and HXH. The first histidine of the second motif is also involved in the catalysis. Features a transmembrane helix in N-terminus. Localized in the cytoplasmic membrane.; Specificity unclear; metallopeptidase 1167210 10977488 zobellia_978 Zobellia galactanivorans metallopeptidase YP_004735427.1 1166233 D 63186 CDS YP_004735428.1 340616975 10977436 1167210..1167539 1 NC_015844.1 Transcriptional regulator belonging to the MerR family. Contains a N-terminal helix-turn-helix DNA binding motif; Forms a dimer; Localized in the cytoplasm; Specificity unclear; MerR-type transcriptional regulator 1167539 10977436 zobellia_979 Zobellia galactanivorans MerR-type transcriptional regulator YP_004735428.1 1167210 D 63186 CDS YP_004735429.1 340616976 10977437 1167624..1168223 1 NC_015844.1 Conserved protein belonging to the LemA family. LemA contains an amino terminal domain predicted as transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain; Localized in the cytoplasmic membrane; Family membership; LemA family protein 1168223 10977437 zobellia_980 Zobellia galactanivorans LemA family protein YP_004735429.1 1167624 D 63186 CDS YP_004735430.1 340616977 10977438 1168230..1168670 1 NC_015844.1 Conserved protein belonging to the DUF477 family; Localized in the cytoplasm; Family membership; hypothetical protein 1168670 10977438 zobellia_981 Zobellia galactanivorans hypothetical protein YP_004735430.1 1168230 D 63186 CDS YP_004735431.1 340616978 10977439 1168651..1169442 1 NC_015844.1 Conserved protein belonging to the DUF477 family; Contains one C-terminal transmembrane segment; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1169442 10977439 zobellia_982 Zobellia galactanivorans membrane protein YP_004735431.1 1168651 D 63186 CDS YP_004735432.1 340616979 10977440 1169561..1170406 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 1170406 10977440 zobellia_983 Zobellia galactanivorans hypothetical protein YP_004735432.1 1169561 D 63186 CDS YP_004735433.1 340616980 10977441 complement(1170403..1173192) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations. Contains a carboxypeptidase regulatory domain (28-112) and the Plug module (127-183) acting as a channel gate; The signal peptide is cleaved between the residues 25 and 26; Family membership; TonB-dependent Receptor 1173192 10977441 zobellia_984 Zobellia galactanivorans TonB-dependent Receptor YP_004735433.1 1170403 R 63186 CDS YP_004735434.1 340616981 10977442 complement(1173333..1174637) 1 NC_015844.1 EngA is a GTPase of unknown physiological role but seems essential for cell viability; Contains two GTPase domain; Belongs to the Era/TrmE GTP-binding protein family, EngA subfamily; Localized in the cytoplasm; High confidence in function and specificity; GTP-binding protein EngA 1174637 engA 10977442 engA Zobellia galactanivorans GTP-binding protein EngA YP_004735434.1 1173333 R 63186 CDS YP_004735435.1 340616982 10977779 complement(1174783..1176318) 1 NC_015844.1 Conserved protein likely adopting a beta-propeller fold; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; hypothetical protein 1176318 10977779 zobellia_986 Zobellia galactanivorans hypothetical protein YP_004735435.1 1174783 R 63186 CDS YP_004735436.1 340616983 10977443 complement(1176426..1177310) 1 NC_015844.1 Era (E. coli Ras-like protein) is a multifunctional GTPase It binds to the 16S rRNA of the 30S subunit and appears to play a role in the assembly of the 30S subunit, possibly by chaperoning the 16S rRNA. Binds both GDP and GTP, has an intrinsic GTPase activity and is essential for cell growth; Contains a N-terminal GTPase domain and a C-terminal KH type-2 domain that is critical for RNA binding; Belongs to the Era/TrmE GTP-binding protein family, Era subfamily; Localized in the cytoplasm; High confidence in function and specificity; GTP-binding protein Era 1177310 eraA 10977443 eraA Zobellia galactanivorans GTP-binding protein Era YP_004735436.1 1176426 R 63186 CDS YP_004735437.1 340616984 10977784 complement(1177297..1178718) 1 NC_015844.1 This permease transports alanine in association with sodium ions. It forms a channel through the cytoplasmic membrane, the interior face being hydrophilic to allow the passage of alanine molecules and sodium ions. Features eleven transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; sodium / alanine symporter 1178718 10977784 zobellia_988 Zobellia galactanivorans sodium / alanine symporter YP_004735437.1 1177297 R 63186 CDS YP_004735438.1 340616985 10974024 complement(1179039..1180025) 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 12 of transposase; Localized in the cytoplasm; Family membership; transposase, family 12 1180025 10974024 zobellia_990 Zobellia galactanivorans transposase, family 12 YP_004735438.1 1179039 R 63186 CDS YP_004735439.1 340616986 10977445 complement(1180012..1180365) 1 NC_015844.1 Probably a cytoplasmic protein; hypothetical protein 1180365 10977445 zobellia_991 Zobellia galactanivorans hypothetical protein YP_004735439.1 1180012 R 63186 CDS YP_004735440.1 340616987 10977446 1180654..1181049 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 1181049 10977446 zobellia_992 Zobellia galactanivorans hypothetical protein YP_004735440.1 1180654 D 63186 CDS YP_004735441.1 340616988 10977447 1181867..1182709 1 NC_015844.1 Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols; Localized in the cytoplasm; High confidence in function and specificity; glycerophosphoryl diester phosphodiesterase 1182709 ugpQ 10977447 ugpQ Zobellia galactanivorans glycerophosphoryl diester phosphodiesterase YP_004735441.1 1181867 D 63186 CDS YP_004735442.1 340616989 10978726 1182848..1183426 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 1183426 10978726 zobellia_994 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004735442.1 1182848 D 63186 CDS YP_004735443.1 340616990 10977448 1183544..1184665 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Specificity unclear; anti-sigma factor 1184665 10977448 zobellia_995 Zobellia galactanivorans anti-sigma factor YP_004735443.1 1183544 D 63186 CDS YP_004735444.1 340616991 10977449 1184895..1188341 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (123-197) and a Plug module (214-344) acting as the channel gate; The signal peptide is cleaved between the residue 17 and 18; Family membership; TonB-dependent transducer 1188341 10977449 zobellia_996 Zobellia galactanivorans TonB-dependent transducer YP_004735444.1 1184895 D 63186 CDS YP_004735445.1 340616992 10977450 1188360..1189838 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 18 and 19; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 1189838 10977450 zobellia_997 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004735445.1 1188360 D 63186 CDS YP_004735446.1 340616993 10977451 1189855..1191399 1 NC_015844.1 Type I phosphodiesterase catalyzes the cleavage of phosphodiester and phosphosulphate bonds in various compounds such as NAD, deoxynucleotides and nucleotide sugars; Contains a signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; Family membership; type I phosphodiesterase 1191399 10977451 zobellia_998 Zobellia galactanivorans type I phosphodiesterase YP_004735446.1 1189855 D 63186 CDS YP_004735447.1 340616994 10977452 complement(1191929..1193449) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 23; Contains a N-terminal transmembrane segment, Localized in the cytoplasmic membrane; Family membership; sulfatase 1193449 10977452 zobellia_999 Zobellia galactanivorans sulfatase YP_004735447.1 1191929 R 63186 CDS YP_004735448.1 340616995 10977453 complement(1193491..1195473) 1 NC_015844.1 Contains an uncleavable signal peptide; localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1195473 10977453 zobellia_1000 Zobellia galactanivorans membrane protein YP_004735448.1 1193491 R 63186 CDS YP_004735449.1 340616996 10974062 complement(1195621..1197276) 1 NC_015844.1 Mucin-desulfating sulfatases hydrolyse the sulfate groups from oligosaccharides present in mucins (heavily glycosylated proteins). In the mucins, the main sulfated sugars are N-acetyl-D-glucosamine-6-sulfate, galactose-6-sulfate and galactose-3-sulfate; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 11; Signal peptide cleaved between the residues 28 and 29; Localized in the periplasmic space; Specificity unclear; mucin-desulfating sulfatase 1197276 mdsA2 10974062 mdsA2 Zobellia galactanivorans mucin-desulfating sulfatase YP_004735449.1 1195621 R 63186 CDS YP_004735450.1 340616997 10978133 complement(1197324..1198787) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 15; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Family membership; sulfatase 1198787 10978133 zobellia_1002 Zobellia galactanivorans sulfatase YP_004735450.1 1197324 R 63186 CDS YP_004735451.1 340616998 10974063 complement(1198777..1199796) 1 NC_015844.1 This protein is Could be a pseudogene; Hypothetical protein; hypothetical protein 1199796 10974063 zobellia_1003 Zobellia galactanivorans hypothetical protein YP_004735451.1 1198777 R 63186 CDS YP_004735452.1 340616999 10974064 complement(1200004..1201665) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 1201665 10974064 zobellia_1004 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004735452.1 1200004 R 63186 CDS YP_004735453.1 340617000 10974065 complement(1201677..1204973) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (131-205), and a Plug module (201-311) acting as the channel gate; The signal peptide is cleaved between the residue 22 and 23; Family membership; TonB-dependent transducer 1204973 10974065 zobellia_1005 Zobellia galactanivorans TonB-dependent transducer YP_004735453.1 1201677 R 63186 CDS YP_004735454.1 340617001 10974066 complement(1205126..1206289) 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 1206289 10974066 zobellia_1006 Zobellia galactanivorans anti-sigma factor YP_004735454.1 1205126 R 63186 CDS YP_004735455.1 340617002 10974067 1206413..1207012 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 1207012 10974067 zobellia_1007 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004735455.1 1206413 D 63186 CDS YP_004735456.1 340617003 10974068 complement(1207068..1207214) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1207214 10974068 zobellia_1008 Zobellia galactanivorans hypothetical protein YP_004735456.1 1207068 R 63186 CDS YP_004735457.1 340617004 10974069 complement(1207175..1207459) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1207459 10974069 zobellia_1009 Zobellia galactanivorans hypothetical protein YP_004735457.1 1207175 R 63186 CDS YP_004735458.1 340617005 10974070 complement(1207535..1208983) 1 NC_015844.1 Endo-1,3-beta-glucanase (Laminarinase) hydrolyzes the 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans. This laminarinase is a modular protein with a N-terminal catalytic module of the family 16 of glycoside hydrolases (GH16), a central carbohydrate binding module of the family 6 (CBM6) and a C-terminal conserved domain of unknown function. Features a signal peptide cleaved between the residues 22 and 23.; High confidence in function and specificity; endo-1,3-beta-glucanase 1208983 lamC 10974070 lamC Zobellia galactanivorans endo-1,3-beta-glucanase YP_004735458.1 1207535 R 63186 CDS YP_004735459.1 340617006 10978074 complement(1209120..1210997) 1 NC_015844.1 Endo-1,3-beta-glucanase (Laminarinase) hydrolyzes the 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans. This laminarinase is a modular protein with a N-terminal catalytic module of the family 64 of glycoside hydrolases (GH64), a central carbohydrate binding module of the family 6 (CBM6) and a C-terminal conserved domain of unknown function. Features a signal peptide cleaved between the residues 20 and 21.; Hypothetical protein; endo-1,3-beta-glucanase 1210997 lamE 10978074 lamE Zobellia galactanivorans endo-1,3-beta-glucanase YP_004735459.1 1209120 R 63186 CDS YP_004735460.1 340617007 10978076 complement(1211316..1214138) 1 NC_015844.1 Protein that consists of an N-terminal periplasmic beta-propeller followed by a C-terminal cytoplasmic domain containing a LuxR-type HTH domain acting as transcrptionnal regulator. A transmembrane segment is present between these two domains. Signal peptide cleaved between the residues 25 and 26; Localized in the cytoplasmic membrane; Family membership; ligand-binding sensor protein 1214138 10978076 zobellia_1012 Zobellia galactanivorans ligand-binding sensor protein YP_004735460.1 1211316 R 63186 CDS YP_004735461.1 340617008 10974071 complement(1214830..1215033) 1 NC_015844.1 Small protein fragment found at the C-terminal extremity of various proteins annotated as transposases and inactivated derivatives that can have until 500 aa. The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 25 of transposases; Putatively localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 1215033 10974071 zobellia_1013 Zobellia galactanivorans hypothetical protein YP_004735461.1 1214830 R 63186 CDS YP_004735462.1 340617009 10974072 complement(1215548..1218334) 1 NC_015844.1 Endo-1,3-beta-glucanase (laminarinase) hydrolyzes the 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans. This laminarinase is a modular protein with a N-terminal catalytic module of the family 16 of glycoside hydrolases (GH16), a central conserved domain of unknown function followed by a carbohydrate binding module of the family 42 (CBM42) and a C-terminal conserved domain of unknown function. Features a signal peptide cleaved between the residues 26 and 27.; High confidence in function and specificity; endo-1,3-beta-glucanase 1218334 lamD 10974072 lamD Zobellia galactanivorans endo-1,3-beta-glucanase YP_004735462.1 1215548 R 63186 CDS YP_004735463.1 340617010 10978075 complement(1218790..1220373) 1 NC_015844.1 Glycoside hydrolase with an unknown substrate specificity. It is a modular enzyme displaying a N-terminal catalytic module belonging to the family 18 of the glycoside hydrolases (GH18) and two C-terminal carbohydrate binding modules belonging to the family 5 of the carbohydrate binding modules that mainly bind to the cellulose and chitin; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Specificity unclear; glycoside hydrolase 1220373 10978075 zobellia_1015 Zobellia galactanivorans glycoside hydrolase YP_004735463.1 1218790 R 63186 CDS YP_004735464.1 340617011 10974073 1220724..1220987 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane.; Hypothetical protein; hypothetical protein 1220987 10974073 zobellia_1016 Zobellia galactanivorans hypothetical protein YP_004735464.1 1220724 D 63186 CDS YP_004735465.1 340617012 10974074 1221397..1222278 1 NC_015844.1 The beta-porphyranases hydrolyze the 1,4-beta-D-galactosidic linkages in porphyrans; Belongs to the family 16 of glycoside hydrolases (GH16); Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; High confidence in function and specificity; beta-porphyranase B 1222278 porB 10974074 porB Zobellia galactanivorans beta-porphyranase B YP_004735465.1 1221397 D 63186 CDS YP_004735466.1 340617013 10978362 1222345..1222611 1 NC_015844.1 Protein fragment found in hypothetical transposases; Putatively localized in the cytoplasm; hypothetical protein 1222611 10978362 zobellia_1018 Zobellia galactanivorans hypothetical protein YP_004735466.1 1222345 D 63186 CDS YP_004735467.1 340617014 10974075 complement(1222665..1223555) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the outer membrane; Hypothetical protein; hypothetical protein 1223555 10974075 zobellia_1019 Zobellia galactanivorans hypothetical protein YP_004735467.1 1222665 R 63186 CDS YP_004735468.1 340617015 10974076 1223949..1224212 1 NC_015844.1 Hypothetical protein; hypothetical protein 1224212 10974076 zobellia_1020 Zobellia galactanivorans hypothetical protein YP_004735468.1 1223949 D 63186 CDS YP_004735469.1 340617016 10974078 complement(1224179..1225792) 1 NC_015844.1 Glycoside hydrolase belonging to the family GH16. The substrate specificity is unclear. Contains a central carbohydrate binding module of the family 6 (CBM6) and a C-terminal domain of unknown function. Features a uncleaved signal peptide.; Specificity unclear; glycoside hydrolase 1225792 10974078 zobellia_1021 Zobellia galactanivorans glycoside hydrolase YP_004735469.1 1224179 R 63186 CDS YP_004735470.1 340617017 10974079 complement(1226008..1226739) 1 NC_015844.1 Dioxygenase catalyzes the incorporation of both atoms of oxygen from one molecule of O2 into the (reduced) substrate. The exact specificity of this enzyme is unknown; Belongs to the phytanoyl-CoA dioxygenase (PhyH) family; Localized in the cytoplasm; Family membership; PhyH family dioxygenase 1226739 10974079 zobellia_1022 Zobellia galactanivorans PhyH family dioxygenase YP_004735470.1 1226008 R 63186 CDS YP_004735471.1 340617018 10974080 complement(1226755..1228776) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1228776 10974080 zobellia_1023 Zobellia galactanivorans periplasmic protein YP_004735471.1 1226755 R 63186 CDS YP_004735472.1 340617019 10974081 complement(1228802..1230172) 1 NC_015844.1 Distantly related to the glycoside hydrolases of the families GH37 and GH63 (clan GH-G); Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; hypothetical protein 1230172 10974081 zobellia_1024 Zobellia galactanivorans hypothetical protein YP_004735472.1 1228802 R 63186 CDS YP_004735473.1 340617020 10974082 complement(1230212..1231570) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Localized in the cytoplasm; Family membership; sulfatase 1231570 10974082 zobellia_1025 Zobellia galactanivorans sulfatase YP_004735473.1 1230212 R 63186 CDS YP_004735474.1 340617021 10974083 complement(1231605..1233908) 1 NC_015844.1 Beta-N-acetylhexosaminidase catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. Belongs to the family 20 of the glycoside hydrolases. Carbonyl oxygen of the C-2 acetamido group of the substrate acts as the catalytic nucleophile/base in the family GH20. They are involved in different pathways such as the N-Glycan degradation, aminosugars metabolism, glycosaminoglycan degradation and globoside metabolism. Signal peptide cleaved between the residues 23 and 24. Localized in the periplasmic space.; High confidence in function and specificity; beta-N-acetylhexosaminidase 1233908 nahA1 10974083 nahA1 Zobellia galactanivorans beta-N-acetylhexosaminidase YP_004735474.1 1231605 R 63186 CDS YP_004735475.1 340617022 10978228 complement(1233914..1236157) 1 NC_015844.1 Alpha-N-acetylglucosaminidase catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. It belongs to the family 89 of the glycoside hydrolases. In human, this enzyme is involved in the degradation of heparan sulfate. Signal peptide cleaved between the residues 20 and 21. Localized in the periplasmic space.; High confidence in function and specificity; alpha-N-acetylglucosaminidase 1236157 nglA 10978228 nglA Zobellia galactanivorans alpha-N-acetylglucosaminidase YP_004735475.1 1233914 R 63186 CDS YP_004735476.1 340617023 10978248 complement(1236191..1236304) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1236304 10978248 zobellia_1028 Zobellia galactanivorans hypothetical protein YP_004735476.1 1236191 R 63186 CDS YP_004735477.1 340617024 10974084 complement(1236314..1237885) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 1237885 10974084 zobellia_1029 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004735477.1 1236314 R 63186 CDS YP_004735478.1 340617025 10974085 complement(1237906..1241163) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (35-108) and the Plug module (125-253) acting as a channel gate; The signal peptide is cleaved between the residues 27 and 28; Family membership; TonB-dependent Receptor 1241163 10974085 zobellia_1030 Zobellia galactanivorans TonB-dependent Receptor YP_004735478.1 1237906 R 63186 CDS YP_004735479.1 340617026 10974087 complement(1241559..1245806) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains three transmembrane segments; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 1245806 10974087 zobellia_1031 Zobellia galactanivorans one-component system sensor protein YP_004735479.1 1241559 R 63186 CDS YP_004735480.1 340617027 10974088 1245973..1246194 1 NC_015844.1 Hypothetical protein; hypothetical protein 1246194 10974088 zobellia_1032 Zobellia galactanivorans hypothetical protein YP_004735480.1 1245973 D 63186 CDS YP_004735481.1 340617028 10974089 1246243..1246335 1 NC_015844.1 Hypothetical protein; hypothetical protein 1246335 10974089 zobellia_1033 Zobellia galactanivorans hypothetical protein YP_004735481.1 1246243 D 63186 CDS YP_004735482.1 340617029 10974090 complement(1246369..1246467) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1246467 10974090 zobellia_1034 Zobellia galactanivorans hypothetical protein YP_004735482.1 1246369 R 63186 CDS YP_004735483.1 340617030 10974091 complement(1246847..1247059) 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 1247059 10974091 zobellia_1035 Zobellia galactanivorans hypothetical protein YP_004735483.1 1246847 R 63186 CDS YP_004735484.1 340617031 10974092 complement(1247366..1248433) 1 NC_015844.1 Conserved protein distantly related to 6-phosphogluconolactonases; Localized in the cytoplasm; Function unclear; 6-phosphogluconolactonase-like protein 1248433 10974092 zobellia_1036 Zobellia galactanivorans 6-phosphogluconolactonase-like protein YP_004735484.1 1247366 R 63186 CDS YP_004735485.1 340617032 10974093 complement(1248568..1249296) 1 NC_015844.1 Conserved protein belonging to the creatinase family, but its exact function is unclear; Localized in the cytoplasm; Family membership; creatinase family protein 1249296 10974093 zobellia_1037 Zobellia galactanivorans creatinase family protein YP_004735485.1 1248568 R 63186 CDS YP_004735486.1 340617033 10974094 complement(1249307..1250290) 1 NC_015844.1 Oxydoreductase NADPH dependent; Belongs to the aldo/keto reductase 2 family; localized in the cytoplasm; Family membership; aldo/keto reductase 1250290 10974094 zobellia_1038 Zobellia galactanivorans aldo/keto reductase YP_004735486.1 1249307 R 63186 CDS YP_004735487.1 340617034 10974095 complement(1250293..1251078) 1 NC_015844.1 Dioxygenase catalyzes the incorporation of both atoms of oxygen from one molecule of O2 into the (reduced) substrate. The exact specificity of this enzyme is unknown; Belongs to the phytanoyl-CoA dioxygenase (PhyH) family; Localized in the cytoplasm; Family membership; PhyH family dioxygenase 1251078 10974095 zobellia_1039 Zobellia galactanivorans PhyH family dioxygenase YP_004735487.1 1250293 R 63186 CDS YP_004735488.1 340617035 10974096 complement(1251098..1253581) 1 NC_015844.1 Modular protein containing a N-terminal 7-bladed beta propeller domain (Galactose oxidase central domain family) and a C-terminal Sodium-solute symporter. Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains thirteen transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sodium/solute symporter 1253581 10974096 zobellia_1040 Zobellia galactanivorans sodium/solute symporter YP_004735488.1 1251098 R 63186 CDS YP_004735489.1 340617036 10974098 complement(1253770..1254666) 1 NC_015844.1 N-acetylneuraminate lyase is involved in sialic acid metabolism. It catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. NanA belongs to the dihidropicolinate synthase (DHDPS) family and forms a homotetramer. Localized in the cytoplasm.; High confidence in function and specificity; N-acetylneuraminate lyase 1254666 nanA1 10974098 nanA1 Zobellia galactanivorans N-acetylneuraminate lyase YP_004735489.1 1253770 R 63186 CDS YP_004735490.1 340617037 10978231 complement(1254752..1255912) 1 NC_015844.1 Sialidase catalyzes the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. It belongs to the family 33 of the glycoside hydrolases. Features a signal peptide cleaved between residues 26 and 27. Localized in the periplasm.; High confidence in function and specificity; sialidase 1255912 nanH 10978231 nanH Zobellia galactanivorans sialidase YP_004735490.1 1254752 R 63186 CDS YP_004735491.1 340617038 10978234 complement(1255974..1256912) 1 NC_015844.1 N-acetylneuraminate lyase is involved in sialic acid metabolism. It catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. NanA belongs to the dihidropicolinate synthase (DHDPS) family and forms a homotetramer. Localized in the cytoplasm.; High confidence in function and specificity; N-acetylneuraminate lyase 1256912 nanA2 10978234 nanA2 Zobellia galactanivorans N-acetylneuraminate lyase YP_004735491.1 1255974 R 63186 CDS YP_004735492.1 340617039 10978232 complement(1257128..1258348) 1 NC_015844.1 N-acetyl-D-glucosamine 2-epimerase catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. It functions as a homodimer, where monomer has an alpha(6)/alpha(6)-barrel structure commonly found in glucoamylases and cellulases This enzyme is involved in sialic acid metabolism. Localized in the cytoplasm.; High confidence in function and specificity; N-acetyl-D-glucosamine 2-epimerase 1258348 10978232 zobellia_1044 Zobellia galactanivorans N-acetyl-D-glucosamine 2-epimerase YP_004735492.1 1257128 R 63186 CDS YP_004735493.1 340617040 10974099 complement(1258422..1259564) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1259564 10974099 zobellia_1045 Zobellia galactanivorans hypothetical protein YP_004735493.1 1258422 R 63186 CDS YP_004735494.1 340617041 10974100 complement(1259564..1260340) 1 NC_015844.1 The enoyl-CoA hydratase (ECH) is an enzyme involved in fatty acid metabolism. It catalyzes the hydratation of 2-trans-enoyl-CoA into 3-hydroxyacyl-CoA.; High confidence in function and specificity; enoyl-CoA hydratase 1260340 paaF 10974100 paaF Zobellia galactanivorans enoyl-CoA hydratase YP_004735494.1 1259564 R 63186 CDS YP_004735495.1 340617042 10978292 complement(1260354..1261559) 1 NC_015844.1 Formyl-coenzyme A transferase catalyzes the first step of the oxalic acid catabolism. It transfers the CoA moiety from formyl-CoA to oxalate . FcrA belongs to the CoA-transferase family III and forms a homodimer. Localized in the cytoplasm.; High confidence in function and specificity; formyl-coenzyme A transferase 1261559 frcA 10978292 frcA Zobellia galactanivorans formyl-coenzyme A transferase YP_004735495.1 1260354 R 63186 CDS YP_004735496.1 340617043 10977844 complement(1261622..1262392) 1 NC_015844.1 Involved in first reduction step of the fatty acid biosynthesis pathway. Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily. Contains a signal peptide cleaved between the residues 27 and 28. Localized in the periplasmic space.; High confidence in function and specificity; 3-oxoacyl-ACP reductase 1262392 fabG3 10977844 fabG3 Zobellia galactanivorans 3-oxoacyl-ACP reductase YP_004735496.1 1261622 R 63186 CDS YP_004735497.1 340617044 10977804 complement(1262513..1263409) 1 NC_015844.1 N-acetylneuraminate lyase is involved in sialic acid metabolism. It catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. NanA belongs to the dihidropicolinate synthase (DHDPS) family and forms a homotetramer. Localized in the cytoplasm.; High confidence in function and specificity; N-acetylneuraminate lyase 1263409 nanA3 10977804 nanA3 Zobellia galactanivorans N-acetylneuraminate lyase YP_004735497.1 1262513 R 63186 CDS YP_004735498.1 340617045 10978233 complement(1263490..1263594) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1263594 10978233 zobellia_1050 Zobellia galactanivorans hypothetical protein YP_004735498.1 1263490 R 63186 CDS YP_004735499.1 340617046 10974102 complement(1263644..1265077) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 20 and 21; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 1265077 10974102 zobellia_1051 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004735499.1 1263644 R 63186 CDS YP_004735500.1 340617047 10974103 complement(1265104..1268442) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (31-104) and the Plug module (120-237) acting as a channel gate; The signal peptide is cleaved between the residues 27 and 28; Family membership; TonB-dependent Receptor 1268442 10974103 zobellia_1052 Zobellia galactanivorans TonB-dependent Receptor YP_004735500.1 1265104 R 63186 CDS YP_004735501.1 340617048 10974104 1268606..1269304 1 NC_015844.1 Transcriptional regulator involved in the repression and/or the positive regulation of genes encoding for enzymes; Contains an N-terminal HTH domain of GntR-like bacterial transcriptional regulators, involved in the binding of the protein to the operator sequences in the DNA and a C-terminal FCD domain that probably binds to a range of effector molecules that regulate the transcription of genes through the action of the N- terminal DNA-binding domain (HTH domain); Localized in the cytoplasm; Family membership; GntR family transcriptional regulator 1269304 10974104 zobellia_1053 Zobellia galactanivorans GntR family transcriptional regulator YP_004735501.1 1268606 D 63186 CDS YP_004735502.1 340617049 10974105 complement(1269790..1271394) 1 NC_015844.1 The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Putative lipoprotein with a signal peptide cleaved between the residues 17 and 18; Possibly localized in the outer membrane; High confidence in function and specificity; N-sulfoglucosamine sulfohydrolase 1271394 sgsA1 10974105 sgsA1 Zobellia galactanivorans N-sulfoglucosamine sulfohydrolase YP_004735502.1 1269790 R 63186 CDS YP_004735503.1 340617050 10978586 complement(1271452..1273287) 1 NC_015844.1 This conserved protein belongs to the (Trans)glycosidase superfamily, which is included in the TIM beta/alpha-barrel fold. This protein is distantly related to the glycoside hydrolases from the family GH36; Localized in the cytoplasm; Family membership; (trans)glycosidase superfamily protein 1273287 10978586 zobellia_1055 Zobellia galactanivorans (trans)glycosidase superfamily protein YP_004735503.1 1271452 R 63186 CDS YP_004735504.1 340617051 10974106 complement(1273514..1275004) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 21 and 22; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 1275004 10974106 zobellia_1056 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004735504.1 1273514 R 63186 CDS YP_004735505.1 340617052 10974107 complement(1275034..1278369) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain (49-100)) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (122-196), and a Plug module (212-338) acting as the channel gate; The signal peptide is cleaved between the residue 22 and 23; Family membership; TonB-dependent transducer 1278369 10974107 zobellia_1057 Zobellia galactanivorans TonB-dependent transducer YP_004735505.1 1275034 R 63186 CDS YP_004735506.1 340617053 10974108 complement(1278595..1279728) 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 1279728 10974108 zobellia_1058 Zobellia galactanivorans anti-sigma factor YP_004735506.1 1278595 R 63186 CDS YP_004735507.1 340617054 10974109 1279893..1280471 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 1280471 10974109 zobellia_1059 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004735507.1 1279893 D 63186 CDS YP_004735508.1 340617055 10974113 1281162..1281653 1 NC_015844.1 Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Belongs to the thioredoxin family; Localized in the cytoplasm; Specificity unclear; thiol-disulfide oxidoreductase 1281653 10974113 zobellia_1062 Zobellia galactanivorans thiol-disulfide oxidoreductase YP_004735508.1 1281162 D 63186 CDS YP_004735509.1 340617056 10974114 1281656..1282354 1 NC_015844.1 Peroxiredoxins are thiol peroxidase. They are involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. The peroxidase reaction comprises two steps centered around a redox- active cysteine called the peroxidatic cysteine. It attacks the peroxide substrate and is oxidized to S-hydroxycysteine (a sulfenic acid). The second step is the regeneration of cysteine from S-hydroxycysteine. This regeneration is due to thiol-containing reductants such as thioredoxin. Features a signal peptide cleaved between the residues 25 and 26. Localized in the periplasm.; Family membership; peroxiredoxin 1282354 10974114 zobellia_1063 Zobellia galactanivorans peroxiredoxin YP_004735509.1 1281656 D 63186 CDS YP_004735510.1 340617057 10974115 1282615..1283190 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1283190 10974115 zobellia_1064 Zobellia galactanivorans hypothetical protein YP_004735510.1 1282615 D 63186 CDS YP_004735511.1 340617058 10974116 complement(1283254..1283445) 1 NC_015844.1 Cold shock proteins (CSPs) help the cell to survive in temperatures lower than optimum growth temperature. CSPs may act as RNA chaperones by destabilizing RNA secondary structures, regulating ribosomal translation, rate of mRNA degradation and termination of transcription; Contains a 'cold-shock domain' (CSD) involved in the single-strand nucleic-acid binding; Localized in the cytoplasm; High confidence in function and specificity; cold shock protein 1283445 cspA1 10974116 cspA1 Zobellia galactanivorans cold shock protein YP_004735511.1 1283254 R 63186 CDS YP_004735512.1 340617059 10977685 complement(1283472..1284629) 1 NC_015844.1 Protein that could be involved in ATP-dependent RNA unwinding in a variety of cellular processes, including ribosome assembly, protein synthesis, and RNA degradation; Contains a DEAD box; Belongs to the helicases superfamily II, DEAD/DEAH box RNA helicase family, DEAD box subfamily; Localized in the cytoplasm; Family membership; DEAD/DEAH RNA helicase 1284629 10977685 zobellia_1066 Zobellia galactanivorans DEAD/DEAH RNA helicase YP_004735512.1 1283472 R 63186 CDS YP_004735513.1 340617060 10974117 complement(1284639..1285640) 1 NC_015844.1 Linoleoyl-CoA desaturase , also known as delta 6-desaturase, is responsible for the conversion of linoleic acid (18:2) to gamma-linolenic acid (18:3 gamma). It uses iron ion as a cofactor. Features five transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; linoleoyl-CoA desaturase 1285640 des6-2 10974117 des6-2 Zobellia galactanivorans linoleoyl-CoA desaturase YP_004735513.1 1284639 R 63186 CDS YP_004735514.1 340617061 10977732 1285990..1286247 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1286247 10977732 zobellia_1068 Zobellia galactanivorans hypothetical protein YP_004735514.1 1285990 D 63186 CDS YP_004735515.1 340617062 10974118 1286459..1286941 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1286941 10974118 zobellia_1069 Zobellia galactanivorans hypothetical protein YP_004735515.1 1286459 D 63186 CDS YP_004735516.1 340617063 10974119 1287191..1288165 1 NC_015844.1 Serine peptidase belonging to the family S12, which includes D-Ala-D-Ala carboxypeptidase B and aminopeptidase DmpB. The active site residues Ser and Lys form the catalytic dyad and are found in the motif Ser-Xaa- Thr-Lys. Localized in the cytoplasm.; Specificity unclear; serine peptidase 1288165 10974119 zobellia_1070 Zobellia galactanivorans serine peptidase YP_004735516.1 1287191 D 63186 CDS YP_004735517.1 340617064 10974121 1288370..1289275 1 NC_015844.1 Conserved protein distantly related to the ribonuclease BN, a 3' to 5' exoribonuclease necessary for 3' maturation of tRNA molecules; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Family membership; ribonuclease BN family protein 1289275 10974121 zobellia_1071 Zobellia galactanivorans ribonuclease BN family protein YP_004735517.1 1288370 D 63186 CDS YP_004735518.1 340617065 10974122 1289390..1290133 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 1290133 10974122 zobellia_1072 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004735518.1 1289390 D 63186 CDS YP_004735519.1 340617066 10974123 1290183..1290422 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 1290422 10974123 zobellia_1073 Zobellia galactanivorans hypothetical protein YP_004735519.1 1290183 D 63186 CDS YP_004735520.1 340617067 10974124 1290460..1291485 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF20 family proteins. This family is predicted to be composed of permeases; Contains eight transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 1291485 10974124 zobellia_1074 Zobellia galactanivorans membrane protein YP_004735520.1 1290460 D 63186 CDS YP_004735521.1 340617068 10974125 1291692..1291991 1 NC_015844.1 Probably modulates the activity of sigma-54 factor; Belongs to the sigma-54 modulation protein/ribosomal protein S30EA family; Localized in the cytoplasm; Function unclear; putative Sigma-54 modulation protein 1291991 10974125 zobellia_1075 Zobellia galactanivorans putative Sigma-54 modulation protein YP_004735521.1 1291692 D 63186 CDS YP_004735522.1 340617069 10974126 1292030..1292191 1 NC_015844.1 Hypothetical protein; hypothetical protein 1292191 10974126 zobellia_1076 Zobellia galactanivorans hypothetical protein YP_004735522.1 1292030 D 63186 CDS YP_004735523.1 340617070 10974127 1292255..1294063 1 NC_015844.1 The exact specificity of this conserved ion transporter is unknown; belongs to the citrate transporter family; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; citrate transporter family protein 1294063 10974127 zobellia_1077 Zobellia galactanivorans citrate transporter family protein YP_004735523.1 1292255 D 63186 CDS YP_004735524.1 340617071 10974128 1294075..1294974 1 NC_015844.1 Mechanosensitive channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation; Contains three transmembrane helices; Belongs to the small-conductance MS channels; Localized in the cytoplasmic membrane; Specificity unclear; small-conductance mechanosensitive channel 1294974 10974128 zobellia_1078 Zobellia galactanivorans small-conductance mechanosensitive channel YP_004735524.1 1294075 D 63186 CDS YP_004735525.1 340617072 10974129 1295050..1296150 1 NC_015844.1 The DUF20 family proteins are predicted to be permeases; Contains eight transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 1296150 10974129 zobellia_1079 Zobellia galactanivorans membrane protein YP_004735525.1 1295050 D 63186 CDS YP_004735526.1 340617073 10974130 complement(1296197..1296382) 1 NC_015844.1 Contains a C-terminal transmembrane segment; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1296382 10974130 zobellia_1080 Zobellia galactanivorans hypothetical protein YP_004735526.1 1296197 R 63186 CDS YP_004735527.1 340617074 10974132 1296427..1296573 1 NC_015844.1 Contains a transmembrane segment; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1296573 10974132 zobellia_1081 Zobellia galactanivorans hypothetical protein YP_004735527.1 1296427 D 63186 CDS YP_004735528.1 340617075 10974133 1296613..1297683 1 NC_015844.1 DNA topoisomerase 1B relaxes supercoiled DNA. Modifies DNA topology by introducing ATP-independent reversible enzyme-linked breaks in the DNA phosphodiester backbone. This is accomplished by cleaving one strand of the DNA duplex and passing the intact complementary strand through the nick. Cleaves DNA after CCCTT sequence. This enzyme is closely related to the DNA topoisomerase 1B from Mimivirus; Belongs to the eukaryotic type I topoisomerase family; Localized in the cytoplasm.; High confidence in function and specificity; DNA topoisomerase 1B 1297683 topA2 10974133 topA2 Zobellia galactanivorans DNA topoisomerase 1B YP_004735528.1 1296613 D 63186 CDS YP_004735529.1 340617076 10978673 1297882..1298331 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1298331 10978673 zobellia_1083 Zobellia galactanivorans hypothetical protein YP_004735529.1 1297882 D 63186 CDS YP_004735530.1 340617077 10974134 1298334..1299149 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF159 family; Localized in the cytoplasm; hypothetical protein 1299149 10974134 zobellia_1084 Zobellia galactanivorans hypothetical protein YP_004735530.1 1298334 D 63186 CDS YP_004735531.1 340617078 10974135 1299314..1299475 1 NC_015844.1 Contains a signal peptide cleaved between the residues 27 and 28 followed by a transmembrane segment; Possibly localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1299475 10974135 zobellia_1085 Zobellia galactanivorans hypothetical protein YP_004735531.1 1299314 D 63186 CDS YP_004735532.1 340617079 10974136 1299504..1299695 1 NC_015844.1 Putative lipoprotein signal peptide cleaved between the residues 22 and 23; Possibly localized in the outer membrane; hypothetical protein 1299695 10974136 zobellia_1086 Zobellia galactanivorans hypothetical protein YP_004735532.1 1299504 D 63186 CDS YP_004735533.1 340617080 10974137 1299966..1300529 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity that acts as transcriptional regulator. This sequence corresponds to the effector domain only, an AraC-type HTH domain; Family membership; two-component system-response regulator, effector domain 1300529 10974137 zobellia_1087 Zobellia galactanivorans two-component system-response regulator, effector domain YP_004735533.1 1299966 D 63186 CDS YP_004735534.1 340617081 10974138 1300539..1300985 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity which acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership; two-component system-response regulator, receiver domain 1300985 10974138 zobellia_1088 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004735534.1 1300539 D 63186 CDS YP_004735535.1 340617082 10974139 1300991..1303990 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two transmembrane segments and two N-terminal PAS/PAC domains involved in many signalling proteins where they are used as a signal sensor domain; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 1303990 10974139 zobellia_1089 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004735535.1 1300991 D 63186 CDS YP_004735536.1 340617083 10974140 1304290..1304433 1 NC_015844.1 Hypothetical protein; hypothetical protein 1304433 10974140 zobellia_1090 Zobellia galactanivorans hypothetical protein YP_004735536.1 1304290 D 63186 CDS YP_004735537.1 340617084 10974141 1304399..1305427 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 1305427 10974141 zobellia_1091 Zobellia galactanivorans AraC family transcriptional regulator YP_004735537.1 1304399 D 63186 CDS YP_004735538.1 340617085 10974142 complement(1305693..1306184) 1 NC_015844.1 Highly conserved protein Belongs to the DUF892 family; Localized in the cytoplasm; Function unclear; hypothetical protein 1306184 10974142 zobellia_1092 Zobellia galactanivorans hypothetical protein YP_004735538.1 1305693 R 63186 CDS YP_004735539.1 340617086 10974143 complement(1306181..1306375) 1 NC_015844.1 Contains a transmembrane segment; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1306375 10974143 zobellia_1093 Zobellia galactanivorans hypothetical protein YP_004735539.1 1306181 R 63186 CDS YP_004735540.1 340617087 10974144 1306401..1306901 1 NC_015844.1 DspA protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction; Forms a homododecamer and the 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited; Localized in the cytoplasm; High confidence in function and specificity; DNA protection during starvation protein 1306901 dpsA2 10974144 dpsA2 Zobellia galactanivorans DNA protection during starvation protein YP_004735540.1 1306401 D 63186 CDS YP_004735541.1 340617088 10977763 complement(1306970..1307407) 1 NC_015844.1 Protein, involved in sensory transduction in microorganisms, and that consists of an N-terminal BLUF (sensors of blue-light using FAD) domain. This domain is involved in sensing blue-light (and possibly redox) using FAD and is Localized in the cytoplasm; Function unclear; expression activator-like protein 1307407 10977763 zobellia_1095 Zobellia galactanivorans expression activator-like protein YP_004735541.1 1306970 R 63186 CDS YP_004735542.1 340617089 10974145 1307523..1307648 1 NC_015844.1 Hypothetical protein; hypothetical protein 1307648 10974145 zobellia_1096 Zobellia galactanivorans hypothetical protein YP_004735542.1 1307523 D 63186 CDS YP_004735543.1 340617090 10974146 complement(1307620..1309941) 1 NC_015844.1 Protein belonging to the bacterial surface antigen family; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 23 and 24; Localized in the outer membrane; Function unclear; surface antigen 1309941 10974146 zobellia_1097 Zobellia galactanivorans surface antigen YP_004735543.1 1307620 R 63186 CDS YP_004735544.1 340617091 10974147 complement(1309944..1314890) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1314890 10974147 zobellia_1098 Zobellia galactanivorans periplasmic protein YP_004735544.1 1309944 R 63186 CDS YP_004735545.1 340617092 10974148 complement(1315052..1315807) 1 NC_015844.1 The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Localized in the cytoplasm; Function unclear; alpha/beta hydrolase-fold protein 1315807 10974148 zobellia_1099 Zobellia galactanivorans alpha/beta hydrolase-fold protein YP_004735545.1 1315052 R 63186 CDS YP_004735546.1 340617093 10974149 complement(1315808..1316251) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1316251 10974149 zobellia_1100 Zobellia galactanivorans hypothetical protein YP_004735546.1 1315808 R 63186 CDS YP_004735547.1 340617094 10974152 complement(1316421..1316930) 1 NC_015844.1 Peroxiredoxins are thiol peroxidase. They are involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. The peroxidase reaction comprises two steps centered around a redox- active cysteine called the peroxidatic cysteine. It attacks the peroxide substrate and is oxidized to S-hydroxycysteine (a sulfenic acid). The second step is the regeneration of cysteine from S-hydroxycysteine. This regeneration is due to thiol-containing reductants such as thioredoxin. Localized in the cytoplasm.; Specificity unclear; peroxiredoxin 1316930 10974152 zobellia_1101 Zobellia galactanivorans peroxiredoxin YP_004735547.1 1316421 R 63186 CDS YP_004735548.1 340617095 10974153 1317185..1318003 1 NC_015844.1 Glucose dehydrogenase catalyses the oxidation of D-glucose without prior phosphorylation to D-beta-gluconolactone using NAD or NADP as a coenzyme; Belongs to the short-chain dehydrogenases/reductases family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity; glucose 1-dehydrogenase 1318003 gdhA 10974153 gdhA Zobellia galactanivorans glucose 1-dehydrogenase YP_004735548.1 1317185 D 63186 CDS YP_004735549.1 340617096 10977886 1318130..1318948 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 1318948 10977886 zobellia_1103 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004735549.1 1318130 D 63186 CDS YP_004735550.1 340617097 10974154 1318997..1319485 1 NC_015844.1 Putative transcriptional regulator; Localized in the cytoplasm; hypothetical protein 1319485 10974154 zobellia_1104 Zobellia galactanivorans hypothetical protein YP_004735550.1 1318997 D 63186 CDS YP_004735551.1 340617098 10974155 1319482..1319613 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1319613 10974155 zobellia_1105 Zobellia galactanivorans hypothetical protein YP_004735551.1 1319482 D 63186 CDS YP_004735552.1 340617099 10974156 1320348..1321703 1 NC_015844.1 Conserved protein involved in exopolysaccharide biosynthesis. Its exact function is unknown. Contains five transmembrane helices. Localized in the cytoplasmic membrane.; Specificity unclear; exopolysaccharide production protein 1321703 10974156 zobellia_1106 Zobellia galactanivorans exopolysaccharide production protein YP_004735552.1 1320348 D 63186 CDS YP_004735553.1 340617100 10974157 1321753..1322016 1 NC_015844.1 Hypothetical protein; hypothetical protein 1322016 10974157 zobellia_1107 Zobellia galactanivorans hypothetical protein YP_004735553.1 1321753 D 63186 CDS YP_004735554.1 340617101 10974158 1322028..1324304 1 NC_015844.1 May be involved in the production and the transport of exopolysaccharides; Contains a N-terminal transmembrane segment; Belongs to the etk/wzc family; Localized in the cytoplasmic membrane; Specificity unclear; tyrosine-protein kinase 1324304 etkA 10974158 etkA Zobellia galactanivorans tyrosine-protein kinase YP_004735554.1 1322028 D 63186 CDS YP_004735555.1 340617102 10977789 1324304..1325662 1 NC_015844.1 May be involved in the Lipopolysaccharide O antigen biosynthesis, translocating the nascent polysaccharidic O-antigen molecules and/or ligating them to lipid A core units; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Function unclear; O-antigen transporter 1325662 10977789 zobellia_1109 Zobellia galactanivorans O-antigen transporter YP_004735555.1 1324304 D 63186 CDS YP_004735556.1 340617103 10974159 1325659..1326984 1 NC_015844.1 Contains ten transmenbrane segments; Localized ion the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1326984 10974159 zobellia_1110 Zobellia galactanivorans membrane protein YP_004735556.1 1325659 D 63186 CDS YP_004735557.1 340617104 10974160 1327071..1328003 1 NC_015844.1 Probably required for the acetyl modification of sugars of the oligosaccharides during the exopolysaccharide biosynthesis; Contains ten transmenbrane segments; Belongs to the acyltransferase 3 family; Localized in the cytoplasmic membrane; Family membership; O-acetyltransferase 1328003 10974160 zobellia_1111 Zobellia galactanivorans O-acetyltransferase YP_004735557.1 1327071 D 63186 CDS YP_004735558.1 340617105 10974161 1328092..1329243 1 NC_015844.1 Probably required for the acetyl modification of sugars of the oligosaccharides during the exopolysaccharide biosynthesis; Contains ten transmenbrane segments; Belongs to the acyltransferase 3 family; Localized in the cytoplasmic membrane; Family membership; acetyltransferase 1329243 10974161 zobellia_1112 Zobellia galactanivorans acetyltransferase YP_004735558.1 1328092 D 63186 CDS YP_004735559.1 340617106 10974162 1329319..1330473 1 NC_015844.1 Mannosyltransferase catalyses the transfer of mannose from GDP-mannose to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Likely involved in the biosynthesis of O-antigen. Localized in the cytoplasm.; High confidence in function and specificity; mannosyltransferase 1330473 10974162 zobellia_1113 Zobellia galactanivorans mannosyltransferase YP_004735559.1 1329319 D 63186 CDS YP_004735560.1 340617107 10974163 1330547..1331806 1 NC_015844.1 Glycosyltransferase that could be involved in the exopolysaccharide or lipopolysaccharide biosynthesis; Belongs to the family 4 of glycosyltransferase (GT4); Localized in the cytoplasm; Specificity unclear; glycosyltransferase 1331806 10974163 zobellia_1114 Zobellia galactanivorans glycosyltransferase YP_004735560.1 1330547 D 63186 CDS YP_004735561.1 340617108 10974164 1331998..1333326 1 NC_015844.1 Protein putatively involved in the exopolysaccharide biosynthesis; Localized in the cytoplasm; Function unclear; Coenzyme A ligase 1333326 10974164 zobellia_1115 Zobellia galactanivorans Coenzyme A ligase YP_004735561.1 1331998 D 63186 CDS YP_004735562.1 340617109 10974165 1333335..1334396 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1334396 10974165 zobellia_1116 Zobellia galactanivorans hypothetical protein YP_004735562.1 1333335 D 63186 CDS YP_004735563.1 340617110 10974166 complement(1334415..1335317) 1 NC_015844.1 Putatively involved in the Lipopolysaccharide core biosynthesis; Belongs to the family 2 of glycosyl transferase (GT2), WaaE/kdtX subfamily; Localized in the cytoplasm; Family membership; glycosyltransferase 1335317 10974166 zobellia_1117 Zobellia galactanivorans glycosyltransferase YP_004735563.1 1334415 R 63186 CDS YP_004735564.1 340617111 10974167 complement(1335317..1335862) 1 NC_015844.1 Protein involved in the biosynthetis of colanic acid, an exopolysaccharide. This protein belongs to the o-acetyltransferase family. Its features three tandem repeats of a [LIV]-G-X(4) hexapeptide, which has been shown to fold as a left-handed parallel beta helix. Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Specificity unclear; colanic acid biosynthesis acetyltransferase 1335862 wcaF 10974167 wcaF Zobellia galactanivorans colanic acid biosynthesis acetyltransferase YP_004735564.1 1335317 R 63186 CDS YP_004735565.1 340617112 10978753 complement(1335855..1336997) 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; Belongs to the family 4 of the glycosyltransferases (GT4); Localized in the cytoplasm; Specificity unclear; glycosyltransferase 1336997 10978753 zobellia_1119 Zobellia galactanivorans glycosyltransferase YP_004735565.1 1335855 R 63186 CDS YP_004735566.1 340617113 10974168 complement(1337026..1338006) 1 NC_015844.1 Mannosyltransferase catalyses the transfer of mannose from GDP-mannose to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Likely involved in the biosynthesis of O-antigen. Localized in the cytoplasm.; High confidence in function and specificity; mannosyltransferase 1338006 10974168 zobellia_1120 Zobellia galactanivorans mannosyltransferase YP_004735566.1 1337026 R 63186 CDS YP_004735567.1 340617114 10974170 complement(1338352..1340541) 1 NC_015844.1 Hypothetical protein predicted to adopts a right handed parallel beta-helix fold; Contains a signal peptide cleaved between the residues 17 and 18; Localized in the periplasmic space; Hypothetical protein; beta-helix fold protein 1340541 10974170 zobellia_1121 Zobellia galactanivorans beta-helix fold protein YP_004735567.1 1338352 R 63186 CDS YP_004735568.1 340617115 10974171 complement(1340538..1341281) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1341281 10974171 zobellia_1122 Zobellia galactanivorans periplasmic protein YP_004735568.1 1340538 R 63186 CDS YP_004735569.1 340617116 10974172 complement(1341286..1342491) 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 1342491 10974172 zobellia_1123 Zobellia galactanivorans hypothetical protein YP_004735569.1 1341286 R 63186 CDS YP_004735570.1 340617117 10974173 complement(1342773..1343276) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1343276 10974173 zobellia_1124 Zobellia galactanivorans periplasmic protein YP_004735570.1 1342773 R 63186 CDS YP_004735571.1 340617118 10974174 1343494..1344879 1 NC_015844.1 Methylmalonyl-CoA mutase is a heterodimer of a small (alpha) and a large (beta) chain. These two subunits are non-identical, yet structurally related chains. MutA codes the small subunit. Methylmalonyl-CoA mutase is an adenosylcobalamin (vitamin B12) dependent enzyme that catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. Localized in the cytoplasm.; High confidence in function and specificity; methylmalonyl-CoA mutase small subunit 1344879 mutA 10974174 mutA Zobellia galactanivorans methylmalonyl-CoA mutase small subunit YP_004735571.1 1343494 D 63186 CDS YP_004735572.1 340617119 10978209 1344892..1346982 1 NC_015844.1 Methylmalonyl-CoA mutase is a heterodimer of a small (alpha) and a large (beta) chain. These two subunits are non-identical, yet structurally related chains. MutB codes the large subunit. Methylmalonyl-CoA mutase is an adenosylcobalamin (vitamin B12) dependent enzyme that catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. Localized in the cytoplasm.; High confidence in function and specificity; methylmalonyl-CoA mutase large subunit 1346982 mutB 10978209 mutB Zobellia galactanivorans methylmalonyl-CoA mutase large subunit YP_004735572.1 1344892 D 63186 CDS YP_004735573.1 340617120 10978210 1347246..1348811 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain. Features also in the N-terminal region a transmembrane helix, a domain of unknown function followed by another transmembrane helix. The histine kinase domain is the C-terminal region. Localized in the cytoplasmic membrane.; Specificity unclear; two-component system-sensor histidine kinase 1348811 10978210 zobellia_1127 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004735573.1 1347246 D 63186 CDS YP_004735574.1 340617121 10974175 1348816..1349211 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, which acts as transcriptional regulator. Localized in the cytoplasm.; Specificity unclear; two-component system-response regulator 1349211 10974175 zobellia_1128 Zobellia galactanivorans two-component system-response regulator YP_004735574.1 1348816 D 63186 CDS YP_004735575.1 340617122 10974025 1349472..1349924 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 1349924 10974025 zobellia_1130 Zobellia galactanivorans hypothetical protein YP_004735575.1 1349472 D 63186 CDS YP_004735576.1 340617123 10974178 complement(1349940..1351373) 1 NC_015844.1 Contains five transmembrane helices in the N-terminal region and a central motif reminiscent of the Planctomycetes cytochrome C motif; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1351373 10974178 zobellia_1131 Zobellia galactanivorans membrane protein YP_004735576.1 1349940 R 63186 CDS YP_004735577.1 340617124 10974179 complement(1351377..1352837) 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF1501 family, in the alkaline-phosphatase clan; Contains a twin-arginine signal peptide; Localized in the periplasmic space; hypothetical protein 1352837 10974179 zobellia_1132 Zobellia galactanivorans hypothetical protein YP_004735577.1 1351377 R 63186 CDS YP_004735578.1 340617125 10974180 complement(1352841..1355174) 1 NC_015844.1 Modular protein with a N-terminal cytochrome C Planctomycetes specific, and two domains of unknown function (DUF1549 and DUF1553) always associated with the Planctomycete cytochrome C domain. Cytochromes C typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes; This protein could result of a lateral transfer from a Planctomycetes; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Function unclear; cytochrome c-containing protein 1355174 10974180 zobellia_1133 Zobellia galactanivorans cytochrome c-containing protein YP_004735578.1 1352841 R 63186 CDS YP_004735579.1 340617126 10974181 complement(1355266..1355364) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1355364 10974181 zobellia_1134 Zobellia galactanivorans hypothetical protein YP_004735579.1 1355266 R 63186 CDS YP_004735580.1 340617127 10974182 complement(1355372..1356559) 1 NC_015844.1 Carboxypeptidase catalyzes the hydrolysis of C-terminal amino acid residues from oligopeptides or polypeptides. This enzyme can release basic, acidic, aromatic, and, to a lesser extent, aliphatic amino acids. Belongs to the family M20 of the metallopeptidase. CpsA binds two co-catalytic zinc ions, which are coordinated by five conserved residues (His/Asp, Asp, Glu, Glu/Asp, His). The zinc ions stabilize the tetrahedral intermediate and activate the catalytic water molecule. Localized in the cytoplasm.; High confidence in function and specificity; carboxypeptidase 1356559 cpsA1 10974182 cpsA1 Zobellia galactanivorans carboxypeptidase YP_004735580.1 1355372 R 63186 CDS YP_004735581.1 340617128 10977672 complement(1356596..1357138) 1 NC_015844.1 Protein Belongs to the YceI (UPF0312) family; Signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Family membership; YceI family protein 1357138 10977672 zobellia_1136 Zobellia galactanivorans YceI family protein YP_004735581.1 1356596 R 63186 CDS YP_004735582.1 340617129 10974183 complement(1357200..1358246) 1 NC_015844.1 Lipoprotein that contains a domain found in some eukaryotic and prokaryotic protein kinase and in eukaryotic proteins required for post-translational sulfatase modification; Putative signal peptide cleaved between the residues 21 and 22; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 1358246 10974183 zobellia_1137 Zobellia galactanivorans membrane protein YP_004735582.1 1357200 R 63186 CDS YP_004735583.1 340617130 10974184 1358453..1359145 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1359145 10974184 zobellia_1138 Zobellia galactanivorans periplasmic protein YP_004735583.1 1358453 D 63186 CDS YP_004735584.1 340617131 10974185 complement(1359148..1359282) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 1359282 10974185 zobellia_1139 Zobellia galactanivorans hypothetical protein YP_004735584.1 1359148 R 63186 CDS YP_004735585.1 340617132 10974186 complement(1359341..1360360) 1 NC_015844.1 NAD(P)-dependent oxidoreductase that adopts a Rossmann fold; belongs to the GFO/IDH/MOCA family; Localized in the cytoplasm; Specificity unclear; NAD(P)-dependent oxidoreductase 1360360 10974186 zobellia_1140 Zobellia galactanivorans NAD(P)-dependent oxidoreductase YP_004735585.1 1359341 R 63186 CDS YP_004735586.1 340617133 10974187 complement(1360430..1361794) 1 NC_015844.1 The outer membrane efflux proteins (OEP) are composed of two repeats of OEP domain to form a trimeric channel continuous, solvent-accessible conduit that spans both the outer membrane and periplasmic space; May be specialized for the signal peptide independent extracellular secretion of a variety of substrates in Gram-negative bacteria (type I secretion system); Signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Family membership; outer membrane efflux protein 1361794 10974187 zobellia_1141 Zobellia galactanivorans outer membrane efflux protein YP_004735586.1 1360430 R 63186 CDS YP_004735587.1 340617134 10974188 complement(1361791..1365102) 1 NC_015844.1 Integral membrane protein involved in drug resistance that belongs to the acrB/acrD/acrF family; Contains 12 transmembrane segments and two large periplasmic domains (each exceeding 300 residues) between helices 1 and 2, and helices 7 and 8. The three transmembrane domains form a large, 30-wide central cavity that spans the cytoplasmic membrane and extends to the cytoplasm; Localized in the cytoplasmic membrane; Family membership; multidrug efflux transporter 1365102 10974188 zobellia_1142 Zobellia galactanivorans multidrug efflux transporter YP_004735587.1 1361791 R 63186 CDS YP_004735588.1 340617135 10974189 complement(1365102..1366238) 1 NC_015844.1 The membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics, solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmic membrane by a N-terminal transmembrane region; participates to the type I secretion system; Family membership; membrane fusion protein 1366238 10974189 zobellia_1143 Zobellia galactanivorans membrane fusion protein YP_004735588.1 1365102 R 63186 CDS YP_004735589.1 340617136 10974190 complement(1366413..1367285) 1 NC_015844.1 Protein receptor with a serine/threonine-protein kinase activity and containing seven leucine-rich repeats that generally folds into an arc or horseshoe shape; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Specificity unclear; Receptor-like protein kinase 1367285 10974190 zobellia_1144 Zobellia galactanivorans Receptor-like protein kinase YP_004735589.1 1366413 R 63186 CDS YP_004735590.1 340617137 10974191 complement(1367460..1369370) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Contains a duplicated ATPase domain; Belongs to the ABC transporter family, EF3 subfamily; Localized in the cytoplasm near of the cytoplasmic membrane by association with a membrane permease component; Family membership; ABC transporter ATPase 1369370 10974191 zobellia_1145 Zobellia galactanivorans ABC transporter ATPase YP_004735590.1 1367460 R 63186 CDS YP_004735591.1 340617138 10974192 1369508..1369924 1 NC_015844.1 Contains two transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1369924 10974192 zobellia_1146 Zobellia galactanivorans membrane protein YP_004735591.1 1369508 D 63186 CDS YP_004735592.1 340617139 10974193 complement(1369902..1370954) 1 NC_015844.1 Protein that consists of a FAD dependent oxidoreductase domain; belongs to the D-amino acid oxidases (DAO) family; Localized in the cytoplasm; Family membership; FAD dependent oxidoreductase 1370954 10974193 zobellia_1147 Zobellia galactanivorans FAD dependent oxidoreductase YP_004735592.1 1369902 R 63186 CDS YP_004735593.1 340617140 10974194 complement(1371046..1371948) 1 NC_015844.1 Protein putatively involved in the gliding motility; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Function unclear; gliding motility protein 1371948 gldN 10974194 gldN Zobellia galactanivorans gliding motility protein YP_004735593.1 1371046 R 63186 CDS YP_004735594.1 340617141 10977911 complement(1372008..1373567) 1 NC_015844.1 Protein involved in the gliding motility; Contains a N-terminal transmembrane segment; Anchored in the cytoplasmic membrane and exposed in the periplasmic space; Function unclear; gliding motility protein 1373567 gldM 10977911 gldM Zobellia galactanivorans gliding motility protein YP_004735594.1 1372008 R 63186 CDS YP_004735595.1 340617142 10977910 complement(1373624..1374280) 1 NC_015844.1 Membrane protein involved in the gliding motility; The GldL protein interacts with the GldK protein to inhibit the motility. GldL alone does not inhibit the motility; Contains two transmembrane segments; Localized in the cytoplasmic membrane; Function unclear; gliding motility membrane protein 1374280 gldL 10977910 gldL Zobellia galactanivorans gliding motility membrane protein YP_004735595.1 1373624 R 63186 CDS YP_004735596.1 340617143 10977909 complement(1374420..1375775) 1 NC_015844.1 Lipoprotein involved in the gliding motility that contains an unknown function domain found in some eukaryotic and prokaryotic protein and in eukaryotic proteins required for post-translational modification of sulfatase; Signal peptide cleaved between the residues 17 and 18; Putatively localized in the outer membrane; Function unclear; gliding motility membrane lipoprotein 1375775 gldK 10977909 gldK Zobellia galactanivorans gliding motility membrane lipoprotein YP_004735596.1 1374420 R 63186 CDS YP_004735597.1 340617144 10977908 complement(1375899..1377056) 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 1377056 10977908 zobellia_1152 Zobellia galactanivorans hypothetical protein YP_004735597.1 1375899 R 63186 CDS YP_004735598.1 340617145 10974196 complement(1377169..1379661) 1 NC_015844.1 The DNA topoisomerase I is responsible primarily for the relaxation of negative supercoils. It has also been involved in knotting and unknotting DNA and in linking complementary rings of single-stranded DNA into double-stranded rings; The type I topoisomerases catalyze the interconversion of DNA topoisomers by transient ATP-independent breakage of single-stranded DNA and the subsequent rejoining of the strands via a protein-DNA link where the hydroxyl group of a tyrosine residue is joined to a 5'-phosphate on DNA; Belongs to the prokaryotic type I topoisomerase family; Localized in the cytoplasm; High confidence in function and specificity; DNA topoisomerase IA 1379661 topA1 10974196 topA1 Zobellia galactanivorans DNA topoisomerase IA YP_004735598.1 1377169 R 63186 CDS YP_004735599.1 340617146 10978672 complement(1379783..1381057) 1 NC_015844.1 Putatively contains a unique copy of LVIVD domain. This domain can be involved a beta propeller fold; Signal peptide of lipoprotein cleaved between the residues 18 and 19; Localized in the outer membrane; Hypothetical protein; hypothetical protein 1381057 10978672 zobellia_1154 Zobellia galactanivorans hypothetical protein YP_004735599.1 1379783 R 63186 CDS YP_004735600.1 340617147 10974197 complement(1381171..1381902) 1 NC_015844.1 Contains four transmembrane segments; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1381902 10974197 zobellia_1155 Zobellia galactanivorans hypothetical protein YP_004735600.1 1381171 R 63186 CDS YP_004735601.1 340617148 10974198 1382045..1383490 1 NC_015844.1 Contains a N-terminal UPF0004 domain of unknown function, a Radical SAM superfamily, MiaB family domain involved in 2-methylthioadenine formation and a C-terminal TRAM domain predicted to bind tRNA and deliver the RNA-modifying enzymatic domain to their targets; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine (SAM); Localized in the cytoplasm; Family membership; MiaB-like tRNA modifying protein 1383490 10974198 zobellia_1156 Zobellia galactanivorans MiaB-like tRNA modifying protein YP_004735601.1 1382045 D 63186 CDS YP_004735602.1 340617149 10974199 1383520..1384788 1 NC_015844.1 These transcriptional regulators consit of two domains: a N-terminal sigma 54 interaction domain that acts as an ATP binding domain (in its N-terminal part) and as sigma 54 binding domain with an ATPase activity (in its C-terminal part), and a Fis-type helix-turn-helix DNA-binding domain in their C-terminal section; Family membership; sigma-54-dependent transcriptional regulator 1384788 10974199 zobellia_1157 Zobellia galactanivorans sigma-54-dependent transcriptional regulator YP_004735602.1 1383520 D 63186 CDS YP_004735603.1 340617150 10974200 1384835..1385353 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer and/or cytoplasmic membrane; Conserved hypothetical protein; lipoprotein 1385353 10974200 zobellia_1158 Zobellia galactanivorans lipoprotein YP_004735603.1 1384835 D 63186 CDS YP_004735604.1 340617151 10974201 1385409..1386329 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 1386329 10974201 zobellia_1159 Zobellia galactanivorans hypothetical protein YP_004735604.1 1385409 D 63186 CDS YP_004735605.1 340617152 10974202 1386337..1386699 1 NC_015844.1 SecG is a membrane subunit of the preprotein translocase complex. Secretion across the inner membrane in some Gram-negative bacteria occurs via the preprotein translocase pathway. The translocase itself comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecCY, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD and SecF). Together with SecY and SecE, SecG forms a multimeric channel through which preproteins are translocated, using both proton motive forces and ATP-driven secretion. SecG has two transmembrane domains, both of which contribute to the recognition of preprotein signal sequences by the translocation complex. Localized in the cytoplasmic membrane.; High confidence in function and specificity; protein-export membrane protein secG 1386699 secG 10974202 secG Zobellia galactanivorans protein-export membrane protein secG YP_004735605.1 1386337 D 63186 CDS YP_004735606.1 340617153 10978577 1386845..1387123 1 NC_015844.1 The 10 kDa chaperonin, also known as GroES protein, binds to the 60 kDa chaperonin (GroEL) in the presence of Mg-ATP and suppresses the ATPase activity of the latter. It forms a heptamer of 7 subunits arranged in a ring. Localized in the cytoplasm.; High confidence in function and specificity; 10 kDa chaperonin 1387123 groS 10978577 groS Zobellia galactanivorans 10 kDa chaperonin YP_004735606.1 1386845 D 63186 CDS YP_004735607.1 340617154 10977952 1387230..1388861 1 NC_015844.1 The 60 kDa chaperonin, also knonwn as GroEL protein, prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. It is essential for the growth of the bacteria. It forms an oligomer of 14 subunits composed of two stacked rings of 7 subunits. This ring structure assembles by self-stimulation in the presence of Mg2+-ATP. Localized in the cytoplasm.; High confidence in function and specificity; 60 kDa chaperonin 1388861 groL 10977952 groL Zobellia galactanivorans 60 kDa chaperonin YP_004735607.1 1387230 D 63186 CDS YP_004735608.1 340617155 10977951 1388951..1389151 1 NC_015844.1 Hypothetical protein; hypothetical protein 1389151 10977951 zobellia_1163 Zobellia galactanivorans hypothetical protein YP_004735608.1 1388951 D 63186 CDS YP_004735609.1 340617156 10974204 complement(1389280..1389636) 1 NC_015844.1 Seems to contain a Heavy metal associated domain (HMA domain) being involved in bacterial resistance to toxic metals; Signal peptide cleaved between the residues 19 and 20; Exported in the periplasmic space; Conserved hypothetical protein; metal transport-like protein 1389636 10974204 zobellia_1164 Zobellia galactanivorans metal transport-like protein YP_004735609.1 1389280 R 63186 CDS YP_004735610.1 340617157 10974205 complement(1389661..1391898) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-98) and the Plug module (115-222) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 1391898 10974205 zobellia_1165 Zobellia galactanivorans TonB-dependent Receptor YP_004735610.1 1389661 R 63186 CDS YP_004735611.1 340617158 10974206 complement(1391916..1394411) 1 NC_015844.1 ActP is a P-type ATPase responsible for copper efflux using ATP hydrolysis for energy. ActP controls copper homeostasis. Belongs to the cation transport P-type ATPase family. Features eight transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; copper-transporting P-type ATPase 1394411 actP 10974206 actP Zobellia galactanivorans copper-transporting P-type ATPase YP_004735611.1 1391916 R 63186 CDS YP_004735612.1 340617159 10977471 complement(1394485..1395003) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA. Also would contain an N-terminal heavy-metal-associated domain (HMA) involved in the transport or detoxification of heavy metals; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 1395003 10977471 zobellia_1167 Zobellia galactanivorans AraC family transcriptional regulator YP_004735612.1 1394485 R 63186 CDS YP_004735613.1 340617160 10974207 complement(1395149..1395562) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 25 and 26; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1395562 10974207 zobellia_1168 Zobellia galactanivorans periplasmic protein YP_004735613.1 1395149 R 63186 CDS YP_004735614.1 340617161 10974208 1395800..1396876 1 NC_015844.1 Lipoprotein signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Hypothetical protein; hypothetical protein 1396876 10974208 zobellia_1169 Zobellia galactanivorans hypothetical protein YP_004735614.1 1395800 D 63186 CDS YP_004735615.1 340617162 10974209 1396978..1397436 1 NC_015844.1 Contains a GAF domain; Localized in the cytoplasm; hypothetical protein 1397436 10974209 zobellia_1170 Zobellia galactanivorans hypothetical protein YP_004735615.1 1396978 D 63186 CDS YP_004735616.1 340617163 10974211 1397610..1399139 1 NC_015844.1 Bifunctional enzyme that catalyses the last two steps in de novo purine biosynthesis. The second last step is catalysed by 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) formyltransferase that catalyses the formylation of AICAR with 10-formyl-tetrahydrofolate to yield 5-formylaminoimidazole-4-carboxamide ribonucleotide (FAICAR) and tetrahydrofolate. The last step is catalysed by IMP (Inosine monophosphate) cyclohydrolase, cyclizing FAICAR to IMP; Belongs to the purH family; Localized in the cytoplasm; High confidence in function and specificity; bifunctional purine biosynthesis protein PurH 1399139 purH 10974211 purH Zobellia galactanivorans bifunctional purine biosynthesis protein PurH YP_004735616.1 1397610 D 63186 CDS YP_004735617.1 340617164 10978409 1399207..1400235 1 NC_015844.1 MreB is involved in formation of the rod shape of the cell. It may act as a negative regulator of ftsI; Belongs to the FtsA/MreB family; Localized in the cytoplasm close to the cell surface, forming filamentous helical structures in the same orientation like F-actin; High confidence in function and specificity; Rod shape-determining protein MreB 1400235 mreB 10978409 mreB Zobellia galactanivorans Rod shape-determining protein MreB YP_004735617.1 1399207 D 63186 CDS YP_004735618.1 340617165 10978180 1400322..1401143 1 NC_015844.1 MreC (murein formation C) is involved in the rod shape determination and more generally in cell shape determination of bacteria whether or not they are rod-shaped; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; High confidence in function and specificity; Rod shape-determining protein MreC 1401143 mreC 10978180 mreC Zobellia galactanivorans Rod shape-determining protein MreC YP_004735618.1 1400322 D 63186 CDS YP_004735619.1 340617166 10978181 1401133..1401642 1 NC_015844.1 Hypothetical protein that could be MreD (murein formation D) involved in formation of the rod shape of the cell; Contains six transmembrane segments; Localized in the cytoplasmic memnbrane; Conserved hypothetical protein; putative rod shape-determining protein MreD 1401642 mreD 10978181 mreD Zobellia galactanivorans putative rod shape-determining protein MreD YP_004735619.1 1401133 D 63186 CDS YP_004735620.1 340617167 10978182 1401689..1403557 1 NC_015844.1 PBP-2 is responsible for the determination of the rod shape of the cel. Synthetizes the cross-linked peptidoglycan from the lipid intermediates; Contains in its N-terminal half part a transmembrane segment and an penicillin insensitive transglycosylase domain (formation of linear glycan strands). In its C-terminal half part, a penicillin- sensitive transpeptidase domain (cross-linking of the peptide subunits) is present; Belongs to the family 51 of glycosyl transferases (GT51); Except for the cytoplasmic membrane anchor region, The bulk of the molecule protrudes into the periplasmic space, where it acts on murein; High confidence in function and specificity; penicillin-binding protein 2, Family GT51 1403557 mrdA 10978182 mrdA Zobellia galactanivorans penicillin-binding protein 2, Family GT51 YP_004735620.1 1401689 D 63186 CDS YP_004735621.1 340617168 10978178 1403547..1404830 1 NC_015844.1 MrdB (RodA) is one of the proteins responsible for the rod shape of the cell. Is required for the expression of the enzymatic activity of the penicillin binding protein 2 (MrdA), which is thought to synthesize peptidoglycan in the step of initiation of cell elongation; Contains ten transmembrane segments; Belongs to the FtsW/RodA/SpoVE family; Localized in the cytoplasmic membrane; High confidence in function and specificity; Rod shape-determining protein RodA 1404830 mrdB 10978178 mrdB Zobellia galactanivorans Rod shape-determining protein RodA YP_004735621.1 1403547 D 63186 CDS YP_004735622.1 340617169 10978179 complement(1404876..1405682) 1 NC_015844.1 Endonuclease acting on both DNA and RNA. Cleaves double-stranded and single-stranded nucleic acids and requires a divalent ion such as magnesium for its activity. A histidine has been shown to be essential for the activity, located in a conserved region which also contains an aspartate that could be implicated in the binding of the divalent ion; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Specificity unclear; DNA/RNA non-specific endonuclease 1405682 10978179 zobellia_1177 Zobellia galactanivorans DNA/RNA non-specific endonuclease YP_004735622.1 1404876 R 63186 CDS YP_004735623.1 340617170 10974212 1405944..1406402 1 NC_015844.1 Peptide methionine sulphoxide reductase reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide to methionine. MsrB is specific for methionine-R-sulfoxides. It activates the cysteine or selenocysteine nucleophile through a unique Cys-Arg-Asp/Glu catalytic triad. Regeneration of the active site occurs through a series of thiol-disulfide exchange steps involving another active site Cys residue and thioredoxin. Localized in the cytoplasm.; High confidence in function and specificity; peptide methionine sulfoxide reductase msrB 1406402 msrB2 10974212 msrB2 Zobellia galactanivorans peptide methionine sulfoxide reductase msrB YP_004735623.1 1405944 D 63186 CDS YP_004735624.1 340617171 10978196 1406399..1406956 1 NC_015844.1 Peptide methionine sulphoxide reductase reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide to methionine. MsrA is specific for methionine-S-sulfoxides. Though their active sites show approximate mirror symmetry, MsrA and MsrB are structurally unrelated. In each case, conserved amino acid motifs mediate the stereo-specific recognition and reduction of the substrate. Thioredoxin acts as a cofactor. Localized in the cytoplasm.; High confidence in function and specificity; peptide methionine sulfoxide reductase msrA 1406956 msrA1 10978196 msrA1 Zobellia galactanivorans peptide methionine sulfoxide reductase msrA YP_004735624.1 1406399 D 63186 CDS YP_004735625.1 340617172 10978192 1407063..1407476 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1407476 10978192 zobellia_1180 Zobellia galactanivorans membrane protein YP_004735625.1 1407063 D 63186 CDS YP_004735626.1 340617173 10974214 1407602..1408090 1 NC_015844.1 Peptide methionine sulphoxide reductase reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide to methionine. MsrA is specific for methionine-S-sulfoxides. Though their active sites show approximate mirror symmetry, MsrA and MsrB are structurally unrelated. In each case, conserved amino acid motifs mediate the stereo-specific recognition and reduction of the substrate. Thioredoxin acts as a cofactor. Localized in the cytoplasm.; High confidence in function and specificity; peptide methionine sulfoxide reductase msrA 1408090 msrA2 10974214 msrA2 Zobellia galactanivorans peptide methionine sulfoxide reductase msrA YP_004735626.1 1407602 D 63186 CDS YP_004735627.1 340617174 10978193 1408423..1409763 1 NC_015844.1 Modular protein with a N-terminal carbohydrate binding module of the family 32 (CBM32) and a C-terminal alginate lyase domain of the family 7 of the polysaccharide lyases (PL7). Alginate lyase catalyzes the eliminative cleavage of polysaccharides containing beta-D- mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. Features a signal peptide cleaved between residues 34 and 35. Likely localized in the outer membrane.; High confidence in function and specificity; alginate lyase 1409763 alyA1 10978193 alyA1 Zobellia galactanivorans alginate lyase YP_004735627.1 1408423 D 63186 CDS YP_004735628.1 340617175 10977511 complement(1409904..1412027) 1 NC_015844.1 This enzyme is a modular protein with a N-terminal domain of unknown function, a central PDZ domain that is a multifunctional protein-protein interaction module binding to a signature motif ([FYST]-X-[FVA]) occurring at the very C-terminus of target proteins and a Carboxy-terminal processing peptidase in C-terminus that shows a specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala, but then cleaves at a variable distance from the C-terminus of the target proteins; The catalytic module belongs to the family S41 of the peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the rsidues 18 and 19; Localized in the outer membrane; Specificity unclear; carboxy-terminal processing peptidase 1412027 10977511 zobellia_1183 Zobellia galactanivorans carboxy-terminal processing peptidase YP_004735628.1 1409904 R 63186 CDS YP_004735629.1 340617176 10974215 1412227..1413006 1 NC_015844.1 SurE is a nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20- 25). Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs. Also plays a significant physiological role in stress-response and is required for the bacterial survival in stationary growth phase. Binds 1 divalent metal cation as a cofactor. Localized in the cytoplasm.; Hypothetical protein; stationary-phase survival protein surE 1413006 surE 10974215 surE Zobellia galactanivorans stationary-phase survival protein surE YP_004735629.1 1412227 D 63186 CDS YP_004735630.1 340617177 10978628 1413071..1413355 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1413355 10978628 zobellia_1185 Zobellia galactanivorans membrane protein YP_004735630.1 1413071 D 63186 CDS YP_004735631.1 340617178 10974216 1413448..1414560 1 NC_015844.1 LpxB catalyzes the condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide. This reaction is the fifth step of lipid A biosynthesis. LpxB belongs to the family 19 of the glycosyltransferases. Localized in the cytoplasm.; High confidence in function and specificity; lipid-A-disaccharide synthase 1414560 lpxB 10974216 lpxB Zobellia galactanivorans lipid-A-disaccharide synthase YP_004735631.1 1413448 D 63186 CDS YP_004735632.1 340617179 10978103 1414553..1415161 1 NC_015844.1 The lipoprotein sprA was identified by genetic as a suppressor of a protease prc mutation. Its exact function is not known. The catalytic dyad is formed by a single conserved cysteine and histidine residues; Belongs to the family C40 of peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 34 and 35; Localized in the cytoplasmic or outer membrane; Specificity unclear; peptidase spr, family C40 1415161 sprA 10978103 sprA Zobellia galactanivorans peptidase spr, family C40 YP_004735632.1 1414553 D 63186 CDS YP_004735633.1 340617180 10978606 1415172..1417190 1 NC_015844.1 Competence proteins are essential for bacterial competence in uptake of extracellular DNA. These proteins may transport DNA across the cell membrane. This competence protein features eleven transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; competence protein 1417190 10978606 zobellia_1188 Zobellia galactanivorans competence protein YP_004735633.1 1415172 D 63186 CDS YP_004735634.1 340617181 10974217 complement(1417212..1418582) 1 NC_015844.1 DtpT a membrane permease responsible for the intake of di- or tri-peptides with the concomitant uptake of a proton. Features twelve transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; Di-/tripeptide transporter 1418582 dtpT 10974217 dtpT Zobellia galactanivorans Di-/tripeptide transporter YP_004735634.1 1417212 R 63186 CDS YP_004735635.1 340617182 10977769 complement(1418710..1420890) 1 NC_015844.1 Dipeptidyl-peptidase IV releases an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline. Belongs to the family S9 of the serine peptidases. The active site residues are in the order Ser, Asp, His in the sequence. The motif around the active site serine is G W S (Y/F) G G. DppA displays a two domain architecture, with a N-terminal eight-bladed beta-propeller and a C-terminal S9 peptidase domain. Features a signal peptide cleaved between the residues 20 and 21. Localized in the periplasm.; High confidence in function and specificity; dipeptidyl peptidase 1420890 dppA1 10977769 dppA1 Zobellia galactanivorans dipeptidyl peptidase YP_004735635.1 1418710 R 63186 CDS YP_004735636.1 340617183 10977759 1421044..1422366 1 NC_015844.1 3-Hydroxy-3-methylglutaryl-coenzyme A reductase catalyzes the reversible conversion of mevalonate into 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA), using coenzyme A and NAD(P) as cofactors. In Archeae, NADP-depedent HMG-CoA reductase is involved in the biosynthesis of the isoprenoids side chains of lipids. Some bacteria, such as Pseudomonas mevalonii, use an NAD-dependent HMG-CoA reductase to deacetylate mevalonate into 3-hydroxy-3-methylglutaryl-CoA. These bacteria can use mevalonate as sole carbon source. Localized in the cytoplasm.; High confidence in function and specificity; 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1422366 mvaA 10977759 mvaA Zobellia galactanivorans 3-hydroxy-3-methylglutaryl-coenzyme A reductase YP_004735636.1 1421044 D 63186 CDS YP_004735637.1 340617184 10978216 1422363..1423277 1 NC_015844.1 Protein that is probably a kinase; belongs to the GHMP (galacto, homoserine, mevalonate, phosphomevalonate) kinase family; Localized in the cytoplasm; Family membership; GHMP kinase family protein 1423277 10978216 zobellia_1192 Zobellia galactanivorans GHMP kinase family protein YP_004735637.1 1422363 D 63186 CDS YP_004735638.1 340617185 10974219 complement(1423338..1425455) 1 NC_015844.1 Large conserved protein distantly related to peptidyl-prolyl cis-trans isomerase; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Family membership; peptidyl-prolyl isomerase family protein 1425455 10974219 zobellia_1193 Zobellia galactanivorans peptidyl-prolyl isomerase family protein YP_004735638.1 1423338 R 63186 CDS YP_004735639.1 340617186 10974220 complement(1425525..1426814) 1 NC_015844.1 Conserved protein that contains a N-terminal transmembrane region of unknown function belonging to the DUF21 family, composed of four helices, two central cystathionine-beta-synthase (CBS) domains and a C-terminal transporter associated domain. CBS domains have been shown to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet. They may play a regulatory role making proteins sensitive to adenosyl carrying ligands. The function of the transporter associated domain is uncertain but might be involved in modulating transport of ion substrates; Localized in the cytoplasmic membrane; Family membership; CBS family protein 1426814 10974220 zobellia_1194 Zobellia galactanivorans CBS family protein YP_004735639.1 1425525 R 63186 CDS YP_004735640.1 340617187 10974221 complement(1426817..1427020) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1427020 10974221 zobellia_1195 Zobellia galactanivorans membrane protein YP_004735640.1 1426817 R 63186 CDS YP_004735641.1 340617188 10974222 complement(1427013..1427621) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1427621 10974222 zobellia_1196 Zobellia galactanivorans hypothetical protein YP_004735641.1 1427013 R 63186 CDS YP_004735642.1 340617189 10974223 complement(1427626..1428999) 1 NC_015844.1 Conserved protein containing three tetratrico peptide repeats (TPRs). TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Family membership; hypothetical protein 1428999 10974223 zobellia_1197 Zobellia galactanivorans hypothetical protein YP_004735642.1 1427626 R 63186 CDS YP_004735643.1 340617190 10974224 complement(1429241..1430527) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1430527 10974224 zobellia_1198 Zobellia galactanivorans periplasmic protein YP_004735643.1 1429241 R 63186 CDS YP_004735644.1 340617191 10974225 complement(1430527..1431315) 1 NC_015844.1 Type III pantothenate kinase catalyzes the phosphorylation of pantothenate, the first step in coenzyme A biosynthesis. Can not utilize a phosphoryl donor other than ATP. It forms a homodimer and binds ammonium or potassium as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; type III pantothenate kinase 1431315 coaX 10974225 coaX Zobellia galactanivorans type III pantothenate kinase YP_004735644.1 1430527 R 63186 CDS YP_004735645.1 340617192 10974026 1432468..1433772 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 15 and 16; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 1433772 10974026 zobellia_1201 Zobellia galactanivorans membrane protein YP_004735645.1 1432468 D 63186 CDS YP_004735646.1 340617193 10974227 1433840..1434337 1 NC_015844.1 Thiosulfate sulfurtransferase catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide; The relatively low affinity of GlpE for both thiosulfate and cyanide suggests that these compounds are not the physiological substrates. Thioredoxin 1 or related dithiol proteins could instead be the physiological sulfur-acceptor substrate; Contains one only rhodanese domain; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; High confidence in function and specificity; thiosulfate sulfurtransferase 1434337 glpE4 10974227 glpE4 Zobellia galactanivorans thiosulfate sulfurtransferase YP_004735646.1 1433840 D 63186 CDS YP_004735647.1 340617194 10977924 1434398..1435075 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1435075 10977924 zobellia_1203 Zobellia galactanivorans hypothetical protein YP_004735647.1 1434398 D 63186 CDS YP_004735648.1 340617195 10974228 1435072..1435887 1 NC_015844.1 Purine nucleoside phosphorylase is involved in Nucleoside catabolism. It catalyzes the cleavage of guanosine or inosine to respective bases and sugar-1-phosphate molecules. Localized in the cytoplasm.; High confidence in function and specificity; Purine nucleoside phosphorylase 1435887 punA 10974228 punA Zobellia galactanivorans Purine nucleoside phosphorylase YP_004735648.1 1435072 D 63186 CDS YP_004735649.1 340617196 10978402 1435977..1436747 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1436747 10978402 zobellia_1205 Zobellia galactanivorans lipoprotein YP_004735649.1 1435977 D 63186 CDS YP_004735650.1 340617197 10974229 1436734..1437438 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases. Localized in the cytoplasm.; Specificity unclear; glycosyltransferase 1437438 10974229 zobellia_1206 Zobellia galactanivorans glycosyltransferase YP_004735650.1 1436734 D 63186 CDS YP_004735651.1 340617198 10974230 complement(1437435..1438508) 1 NC_015844.1 N-Acetylmuramoyl-L-alanine amidase hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in peptidoglycan; Contains a signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; High confidence in function and specificity; N-acetylmuramoyl-L-alanine amidase 1438508 10974230 zobellia_1207 Zobellia galactanivorans N-acetylmuramoyl-L-alanine amidase YP_004735651.1 1437435 R 63186 CDS YP_004735652.1 340617199 10974231 complement(1438699..1439580) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 1439580 10974231 zobellia_1208 Zobellia galactanivorans AraC family transcriptional regulator YP_004735652.1 1438699 R 63186 CDS YP_004735653.1 340617200 10974232 complement(1439644..1440681) 1 NC_015844.1 FAD-dependent amine oxidoreductase of unknown substrate specificity; Belongs to the amine oxydase family; Localized in the cytoplasm; Specificity unclear; FAD-dependent amine oxidoreductase 1440681 10974232 zobellia_1209 Zobellia galactanivorans FAD-dependent amine oxidoreductase YP_004735653.1 1439644 R 63186 CDS YP_004735654.1 340617201 10974233 complement(1440684..1440986) 1 NC_015844.1 The exact function of this conserved protein is not known; belongs to the carboxymuconolactone decarboxylase family; Localized in the cytoplasm; Family membership; carboxymuconolactone decarboxylase family protein 1440986 10974233 zobellia_1210 Zobellia galactanivorans carboxymuconolactone decarboxylase family protein YP_004735654.1 1440684 R 63186 CDS YP_004735655.1 340617202 10974235 complement(1441082..1441828) 1 NC_015844.1 HdhA catalyzes the 7-alpha-dehydroxylation of cholic acid, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid. It forms a homotetramer and binds one NAD cofactor by subunit. Belongs to the short chain dehydrogenase family. Localized in the cytoplasm.; Hypothetical protein; 7-alpha-hydroxysteroid dehydrogenase 1441828 hdhA 10974235 hdhA Zobellia galactanivorans 7-alpha-hydroxysteroid dehydrogenase YP_004735655.1 1441082 R 63186 CDS YP_004735656.1 340617203 10977962 1441980..1442612 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1442612 10977962 zobellia_1212 Zobellia galactanivorans hypothetical protein YP_004735656.1 1441980 D 63186 CDS YP_004735657.1 340617204 10974236 1442621..1443424 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 1443424 10974236 zobellia_1213 Zobellia galactanivorans membrane protein YP_004735657.1 1442621 D 63186 CDS YP_004735658.1 340617205 10974237 1443527..1444057 1 NC_015844.1 Formylmethionine deformylase or peptide deformylase (PDF) is an essential metalloenzyme required for the removal of the formyl group at the N-terminal Met of nascent polypeptide chains in eubacteria. The enzyme acts as a monomer and binds a single zinc ion. Catalytic efficiency strongly depends on the identity of the bound metal; Localized in the cytoplasm; High confidence in function and specificity; formylmethionine deformylase 1444057 defB 10974237 defB Zobellia galactanivorans formylmethionine deformylase YP_004735658.1 1443527 D 63186 CDS YP_004735659.1 340617206 10977729 complement(1444058..1445323) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1445323 10977729 zobellia_1215 Zobellia galactanivorans periplasmic protein YP_004735659.1 1444058 R 63186 CDS YP_004735660.1 340617207 10974238 complement(1445405..1446124) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1446124 10974238 zobellia_1216 Zobellia galactanivorans lipoprotein YP_004735660.1 1445405 R 63186 CDS YP_004735661.1 340617208 10974239 complement(1446126..1447127) 1 NC_015844.1 Glycoside hydrolases hydrolyse the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non-carbohydrate moiety; Belongs to the family 13 of the glycoside hydrolases; Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Specificity unclear; glycoside hydrolase 1447127 10974239 zobellia_1217 Zobellia galactanivorans glycoside hydrolase YP_004735661.1 1446126 R 63186 CDS YP_004735662.1 340617209 10974240 complement(1447174..1448058) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1448058 10974240 zobellia_1218 Zobellia galactanivorans periplasmic protein YP_004735662.1 1447174 R 63186 CDS YP_004735663.1 340617210 10974241 complement(1448092..1448811) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1448811 10974241 zobellia_1219 Zobellia galactanivorans periplasmic protein YP_004735663.1 1448092 R 63186 CDS YP_004735664.1 340617211 10974242 1449045..1450418 1 NC_015844.1 The pyridine nucleotide-disulphide reductases use the isoalloxazine ring of FAD to shuttle reducing equivalents from NAD(P)H to a Cys residue that is usually a part of a redox-active disulphide bridge. In a second step, the reduced disulphide reduces the substrate; Uses the FAD as cofactors; Contains a N-terminal Pyridine nucleotide-disulphide oxidoreductase domain; Belongs to the family of pyridine nucleotide-disulphide oxidoreductases; Localized in the cytoplasm; Family membership; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 1450418 10974242 zobellia_1220 Zobellia galactanivorans FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_004735664.1 1449045 D 63186 CDS YP_004735665.1 340617212 10974243 1450499..1452079 1 NC_015844.1 Oxidoreductase which contains two 4Fe-4S binding domains and eight transmembrane segemnts; Localized in the cytoplasmic membrane; Function unclear; (2[4Fe-4S])-containing oxidoreductase 1452079 10974243 zobellia_1221 Zobellia galactanivorans (2[4Fe-4S])-containing oxidoreductase YP_004735665.1 1450499 D 63186 CDS YP_004735666.1 340617213 10974244 1452173..1452655 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1452655 10974244 zobellia_1222 Zobellia galactanivorans hypothetical protein YP_004735666.1 1452173 D 63186 CDS YP_004735667.1 340617214 10974245 1452652..1455051 1 NC_015844.1 Alpha-L-rhamnosidase catalyzes the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides. It belongs to the family 78 of the glycoside hydrolases. Features an uncleaved signal peptide. Localized in the cytoplasmic membrane.; High confidence in function and specificity; alpha-L-rhamnosidase 1455051 rhaB 10974245 rhaB Zobellia galactanivorans alpha-L-rhamnosidase YP_004735667.1 1452652 D 63186 CDS YP_004735668.1 340617215 10978453 1455061..1455756 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases. Localized in the cytoplasm.; Specificity unclear; glycosyltransferase 1455756 10978453 zobellia_1224 Zobellia galactanivorans glycosyltransferase YP_004735668.1 1455061 D 63186 CDS YP_004735669.1 340617216 10974246 1455758..1457242 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases and is closely related to the cellulose/mannan/chitin synthase subfamily. Features one N-terminal transmembrane helix and five C-terminal transmembrane helices. Integral cytoplasmic membrane protein.; Specificity unclear; glycosyltransferase 1457242 10974246 zobellia_1225 Zobellia galactanivorans glycosyltransferase YP_004735669.1 1455758 D 63186 CDS YP_004735670.1 340617217 10974247 1457310..1458671 1 NC_015844.1 Contains eleven transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1458671 10974247 zobellia_1226 Zobellia galactanivorans membrane protein YP_004735670.1 1457310 D 63186 CDS YP_004735671.1 340617218 10974248 1458890..1459510 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule. Belongs to Gcn5 or GNAT actyltransferase family. Localized in the cytoplasm.; Family membership; GCN5-like N-acetyltransferase 1459510 10974248 zobellia_1227 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004735671.1 1458890 D 63186 CDS YP_004735672.1 340617219 10974249 1459565..1460755 1 NC_015844.1 Argininosuccinate synthase (AS) is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate; Belongs to the argininosuccinate synthase family, type 1 subfamily; Localized in the cytoplasm; High confidence in function and specificity; argininosuccinate synthase 1460755 argG 10974249 argG Zobellia galactanivorans argininosuccinate synthase YP_004735672.1 1459565 D 63186 CDS YP_004735673.1 340617220 10977537 1460748..1461722 1 NC_015844.1 N-acetyl-gamma-glutamyl-phosphate reductase is involved in the third step of the arginine biosynthesis pathway. It converts, in presence of NADP, the N-acetyl-L-glutamate 5-semialdehyde to N-acetyl-5-glutamyl phosphate; Belongs to the NAGSA dehydrogenase family, type 1 subfamily; Localized in the cytoplasm; High confidence in function and specificity; N-acetyl-gamma-glutamyl-phosphate reductase 1461722 argC 10977537 argC Zobellia galactanivorans N-acetyl-gamma-glutamyl-phosphate reductase YP_004735673.1 1460748 D 63186 CDS YP_004735674.1 340617221 10977533 1461794..1462594 1 NC_015844.1 Delta 1-pyrroline-5-carboxylate reductase (P5CR) is the enzyme that catalyzes the terminal step in the biosynthesis of proline from glutamate: the NAD(P) dependent oxidation of 1-pyrroline-5-carboxylate into proline; Localized in the cytoplasm; High confidence in function and specificity; pyrroline-5-carboxylate reductase 1462594 proC2 10977533 proC2 Zobellia galactanivorans pyrroline-5-carboxylate reductase YP_004735674.1 1461794 D 63186 CDS YP_004735675.1 340617222 10978389 1462649..1463773 1 NC_015844.1 Acetylornithine aminotransferase catalyzes the transfer of an amino group from acetylornithine to alpha-ketoglutarate, yielding N-acetyl-glutamic-5-semi-aldehyde and glutamic acid. This is the fourth step in the arginine biosynthesis pathway. ArgD is also involved in the urea cycle. This enzyme uses the pyridoxal phosphate as cofactor linked to a conserved lysine residue. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Localized in the cytoplasm.; High confidence in function and specificity; acetylornithine aminotransferase 1463773 argD 10978389 argD Zobellia galactanivorans acetylornithine aminotransferase YP_004735675.1 1462649 D 63186 CDS YP_004735676.1 340617223 10977534 1463773..1464972 1 NC_015844.1 Gamma-glutamyl phosphate reductase (GPR) is the enzyme that catalyzes the second step in the biosynthesis of proline from glutamate: the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate; Belongs to the aldehyde dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity; gamma-glutamyl phosphate reductase 1464972 proA2 10977534 proA2 Zobellia galactanivorans gamma-glutamyl phosphate reductase YP_004735676.1 1463773 D 63186 CDS YP_004735677.1 340617224 10978385 1465036..1465824 1 NC_015844.1 Glutamate 5-kinase catalyses the first step in the biosynthesis of proline: the ATP-dependent phosphorylation of glutamate to glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline; It belongs to the larger family of aspartokinases; Localized in the cytoplasm; High confidence in function and specificity; glutamate 5-kinase 1465824 proB2 10978385 proB2 Zobellia galactanivorans glutamate 5-kinase YP_004735677.1 1465036 D 63186 CDS YP_004735678.1 340617225 10978387 1465873..1466808 1 NC_015844.1 N-acetylornithine carbamoyltransferase catalyzes the convertion of N-acetylornithine to N-acetylcitrulline and has no catalytic activity with L-ornithine as substrate. ArgF' does not feature the SMG motif which is conserved in the canonical ArgF (L-ornithine to L- citrulline). In this alternative pathway, N-acetyl-L- citrulline is likely deacetylated by ArgE; Localized in the cytoplasm; High confidence in function and specificity; N-acetylornithine carbamoyltransferase 1466808 argF' 10978387 argF' Zobellia galactanivorans N-acetylornithine carbamoyltransferase YP_004735678.1 1465873 D 63186 CDS YP_004735679.1 340617226 10977536 1466813..1467586 1 NC_015844.1 Acetylglutamate kinase is involved in the second step of the arginine biosynthesis pathway. It converts, in presence of ATP, the N-acetyl-L-glutamate to N-acetyl-L-glutamate 5-phosphate; Localized in the cytoplasm; High confidence in function and specificity; acetylglutamate kinase 1467586 argB 10977536 argB Zobellia galactanivorans acetylglutamate kinase YP_004735679.1 1466813 D 63186 CDS YP_004735680.1 340617227 10977532 1467589..1468659 1 NC_015844.1 Acetylornithine deacetylase catalyzes the fifth step of the arginine biosynthesis pathway, converting the 2-N-acetyl-L-ornithine to L-ornithine and acetate. L-ornithine is also a branchpoint in the synthesis of polyamines. ArgE binds two zinc ions per monomer of protein; Belongs to the family M20A of the metallopeptidases; Localized in the cytoplasm; High confidence in function and specificity; acetylornithine deacetylase 1468659 argE 10977532 argE Zobellia galactanivorans acetylornithine deacetylase YP_004735680.1 1467589 D 63186 CDS YP_004735681.1 340617228 10977535 1468736..1470016 1 NC_015844.1 Argininosuccinate lyase is involved in the eighth and last step of the arginine biosynthesis pathway. It converts the Omega-N-(L-arginino)succinate to fumarate and L-arginine; Belongs to the fumarate lyase family. Localized in the cytoplasm; High confidence in function and specificity; argininosuccinate lyase 1470016 argH 10977535 argH Zobellia galactanivorans argininosuccinate lyase YP_004735681.1 1468736 D 63186 CDS YP_004735682.1 340617229 10977538 1470048..1471652 1 NC_015844.1 Aminopeptidase catalyzes the hydrolysis of N-terminal amino-acid residues from oligopeptides or polypeptides. This enzyme belongs to the family M1 of the peptidases. A catalytic zinc ion is bound by two histidines and a glutamate. The histidines are within an 'HEXXH' motif on one long helix with the glutamate on another antiparallel helix. The catalytic mechanism is believed to involve activation of a water molecule by the zinc ion. The glutamate of the HEXXH motif is known to be important for catalysis and a tyrosine may also be involved. Features a signal peptide cleaved between the residues 25 and 26. Localized in the periplasm.; Specificity unclear; aminopeptidase 1471652 10977538 zobellia_1238 Zobellia galactanivorans aminopeptidase YP_004735682.1 1470048 D 63186 CDS YP_004735683.1 340617230 10974251 complement(1471852..1472556) 1 NC_015844.1 Enzyme responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA by rotation of the C1'-N-1 glycosidic bond of uridine to a C1'-C5; Contains a N-terminal S4 RNA-binding domain that probably mediates binding to RNA.; Belongs to the pseudouridine synthase RsuA family; localized in the cytoplasm; High confidence in function and specificity; ribosomal large subunit pseudouridine synthase B 1472556 rluB 10974251 rluB Zobellia galactanivorans ribosomal large subunit pseudouridine synthase B YP_004735683.1 1471852 R 63186 CDS YP_004735684.1 340617231 10978469 complement(1472723..1473673) 1 NC_015844.1 Nitrilases, involved in the reduction of organic nitrogen compounds and ammonia production, are enzymes that convert nitriles into their corresponding acids and ammonia by cleavage of the carbon-nitrogen bonds. They acts on a wide range of aromatic nitriles including (indol- 3-yl)-acetonitrile, and also on some aliphatic nitriles, and on the corresponding acid amides; Belongs to the CN hydrolase family; Localized in the cytoplasm; Specificity unclear; nitrilase 1473673 nitA 10978469 nitA Zobellia galactanivorans nitrilase YP_004735684.1 1472723 R 63186 CDS YP_004735685.1 340617232 10978255 complement(1473673..1474578) 1 NC_015844.1 Multi-pass membrane protein that contains eight transmembrane segments; Localized in the cytoplasmic membrane; Family membership; prenyltransferase family protein 1474578 10978255 zobellia_1241 Zobellia galactanivorans prenyltransferase family protein YP_004735685.1 1473673 R 63186 CDS YP_004735686.1 340617233 10974252 complement(1474591..1475529) 1 NC_015844.1 Mevalonate kinase catalyses the phosphorylation of mevalonate to phosphomevalonate from AT as donor; Uses the magnesium ions as cofactor; CTP, GTP and UTP can also act as donors; Belongs to the GHMP kinase family; Localized in the cytoplasm; High confidence in function and specificity; Mevalonate kinase 1475529 mvkA 10974252 mvkA Zobellia galactanivorans Mevalonate kinase YP_004735686.1 1474591 R 63186 CDS YP_004735687.1 340617234 10978219 complement(1475812..1476897) 1 NC_015844.1 Mevalonate diphosphate decarboxylase or diphosphomevalonate decarboxylase catalyzes the decarboxylation of mevalonate pyrophosphate to isopentyl pyrophosphate (IPP), the last step in the synthesis of IPP in the mevalonate pathway. Mevalonate is a key intermediate in the biosynthesis of sterols and non-sterol isoprenes; Belongs to the GHMP kinase domain superfamily; Localized in the cytoplasm; High confidence in function and specificity; Mevalonate diphosphate decarboxylase 1476897 mvdA 10978219 mvdA Zobellia galactanivorans Mevalonate diphosphate decarboxylase YP_004735687.1 1475812 R 63186 CDS YP_004735688.1 340617235 10978218 1476990..1477463 1 NC_015844.1 Protein possibly involved in the carotenoid biosynthesis; Contains five transmembrane segments; Belongs to the TspO/BZRP family; Localized in the cytoplasmic membrane; Function unclear; protein CrtK 1477463 crtK 10978218 crtK Zobellia galactanivorans protein CrtK YP_004735688.1 1476990 D 63186 CDS YP_004735689.1 340617236 10977680 complement(1477471..1478010) 1 NC_015844.1 Protein of unknown function; Belongs to the DUF1697 family; Localized in the cytoplasm; hypothetical protein 1478010 10977680 zobellia_1245 Zobellia galactanivorans hypothetical protein YP_004735689.1 1477471 R 63186 CDS YP_004735690.1 340617237 10974253 complement(1478007..1479293) 1 NC_015844.1 This is a family that may include proteins with a dinucleotide-binding motif (Rossman fold), including oxidoreductases and dehydrogenases; Seems to contain a FAD binding domain also found in the pyridine nucleotide-disulphide reductases (PNDR); Localized in the cytoplasm; Function unclear; flavoprotein 1479293 10974253 zobellia_1246 Zobellia galactanivorans flavoprotein YP_004735690.1 1478007 R 63186 CDS YP_004735691.1 340617238 10974254 complement(1479293..1480042) 1 NC_015844.1 Glycerophosphoryl diester phosphodiesterase hydrolyzes deacylated phospholipids to G3P and the corresponding alcohols; Signal peptide of lipoprotein cleaved between the residues 17 and 18; Localized in the outer membrane; High confidence in function and specificity; glycerophosphoryl diester phosphodiesterase 1480042 glpQ 10974254 glpQ Zobellia galactanivorans glycerophosphoryl diester phosphodiesterase YP_004735691.1 1479293 R 63186 CDS YP_004735692.1 340617239 10977927 complement(1480049..1481827) 1 NC_015844.1 Glycoside hydrolases hydrolyse the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non-carbohydrate moiety. Belongs to the family 13 of the glycoside hydrolases.; Specificity unclear; glycoside hydrolase 1481827 10977927 zobellia_1248 Zobellia galactanivorans glycoside hydrolase YP_004735692.1 1480049 R 63186 CDS YP_004735693.1 340617240 10974255 complement(1481831..1484134) 1 NC_015844.1 Maltose phosphorylase catalyzes the conversion of maltose and inorganic phosphate into beta-D-glucose-1-phosphate and glucose. It belongs to the family 65 of the glycoside hydrolases. Involved in the maltose metabolism.; High confidence in function and specificity; maltose phosphorylase 1484134 mapA 10974255 mapA Zobellia galactanivorans maltose phosphorylase YP_004735693.1 1481831 R 63186 CDS YP_004735694.1 340617241 10978124 complement(1484170..1484832) 1 NC_015844.1 Beta-phosphoglucomutase is involved in maltose metabolism. It catalyzes the reversible transformation of glucose 6-phosphate and beta-glucose 1-phosphate. Localized in the cytoplasm.; High confidence in function and specificity; beta-phosphoglucomutase 1484832 pgmB 10978124 pgmB Zobellia galactanivorans beta-phosphoglucomutase YP_004735694.1 1484170 R 63186 CDS YP_004735695.1 340617242 10978339 complement(1484906..1485940) 1 NC_015844.1 The LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of operons; They contain a N-terminal lacI-type HTH domain involved in the binding of the protein to the operator sequences in the DNA and a C- terminal periplasmic binding protein domain that are the primary receptors for chemotaxis and transport of many sugar based solutes that act as inducers; Localized in the cytoplasm; Family membership; LacI-type transcriptional regulator 1485940 10978339 zobellia_1251 Zobellia galactanivorans LacI-type transcriptional regulator YP_004735695.1 1484906 R 63186 CDS YP_004735696.1 340617243 10974257 1486287..1489412 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (24-97) and the Plug module (113-240) acting as a channel gate; The signal peptide is cleaved between the residues 23 and 24; Family membership; TonB-dependent Receptor 1489412 10974257 zobellia_1252 Zobellia galactanivorans TonB-dependent Receptor YP_004735696.1 1486287 D 63186 CDS YP_004735697.1 340617244 10974258 1489423..1490997 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 1490997 10974258 zobellia_1253 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004735697.1 1489423 D 63186 CDS YP_004735698.1 340617245 10974259 complement(1491104..1492255) 1 NC_015844.1 Contains a central transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1492255 10974259 zobellia_1254 Zobellia galactanivorans membrane protein YP_004735698.1 1491104 R 63186 CDS YP_004735699.1 340617246 10974260 1492467..1495313 1 NC_015844.1 Enzyme belonging to the family 2 of glycoside hydrolases (GH2) which catalyzes the hydrolysis of the beta-1,4 linkage at the terminal non-reducing of beta-D-galactosides, releasing a beta-D-galactose residue; Signal peptide cleaved between residues 22 and 23; Localized in the periplasmic space; High confidence in function and specificity; beta-galactosidase 1495313 bgaD 10974260 bgaD Zobellia galactanivorans beta-galactosidase YP_004735699.1 1492467 D 63186 CDS YP_004735700.1 340617247 10977596 1495590..1498568 1 NC_015844.1 The alpha subunit of DNA polymerase III is responsible of the polymerase activity; Contains a N-terminal PHP domain (phosphoesterase) and a C-terminal OB module (oligonucleotide/oligosaccharide-binding fold) involved in the DNA binding; The DNA polymerase III or replicase is responsible for most of the replicative synthesis in bacteria. It also exhibits a 3' to 5' exonuclease proofreading activity; Localized in the cytoplasm; High confidence in function and specificity; DNA polymerase III subunit alpha 1498568 dnaE2 10977596 dnaE2 Zobellia galactanivorans DNA polymerase III subunit alpha YP_004735700.1 1495590 D 63186 CDS YP_004735701.1 340617248 10977751 1498561..1499778 1 NC_015844.1 The DNA polymerase IV is a poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. It copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from polIII; Induced by SOS response; Contains a umuC domain; Localized in the cytoplasm; High confidence in function and specificity; DNA polymerase IV 1499778 dinB2 10977751 dinB2 Zobellia galactanivorans DNA polymerase IV YP_004735701.1 1498561 D 63186 CDS YP_004735702.1 340617249 10977745 complement(1499894..1501546) 1 NC_015844.1 Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of pro-and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains fourteen transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sodium/solute symporter 1501546 10977745 zobellia_1258 Zobellia galactanivorans sodium/solute symporter YP_004735702.1 1499894 R 63186 CDS YP_004735703.1 340617250 10974261 1501719..1505042 1 NC_015844.1 ASPIC and UnbV sequences are found associated with tetratrico peptide repeat in several paralogous proteins in Rhodopirellula baltica and with FG-GAP repeats in several eukaryotic integrin-like proteins and in several other bacterial proteins. The FG-GAP repeat has been predicted to fold into a beta propeller structure. The FG- GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding; Contains a signal peptide of lipoprotein cleaved between the residues 19 and 20; Protein putatively localized in the cytoplasmic membrane; Function unclear; ASPIC/UnbV-like protein 1505042 10974261 zobellia_1259 Zobellia galactanivorans ASPIC/UnbV-like protein YP_004735703.1 1501719 D 63186 CDS YP_004735704.1 340617251 10974262 1505044..1508403 1 NC_015844.1 ASPIC and UnbV sequences are found associated with tetratrico peptide repeat in several paralogous proteins in Rhodopirellula baltica and with FG-GAP repeats in several eukaryotic integrin-like proteins and in several other bacterial proteins; The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding; The FG-GAP repeat has been predicted to fold into a beta propeller structure; Contains a signal peptide of lipoprotein cleaved between the residues 25 and 26; Protein putatively localized in the outer membrane; Function unclear; ASPIC/UnbV-like protein 1508403 10974262 zobellia_1260 Zobellia galactanivorans ASPIC/UnbV-like protein YP_004735704.1 1505044 D 63186 CDS YP_004735705.1 340617252 10974264 1508404..1511709 1 NC_015844.1 ASPIC and UnbV sequences are found associated with tetratrico peptide repeat in several paralogous proteins in Rhodopirellula baltica and with FG-GAP repeats in several eukaryotic integrin-like proteins and in several other bacterial proteins; The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding; The FG-GAP repeat has been predicted to fold into a beta propeller structure; Contains a signal peptide of lipoprotein cleaved between the residues 34 and 35; Protein putatively localized in the cytoplasmic membrane; Function unclear; ASPIC/UnbV-like protein 1511709 10974264 zobellia_1261 Zobellia galactanivorans ASPIC/UnbV-like protein YP_004735705.1 1508404 D 63186 CDS YP_004735706.1 340617253 10974265 1511717..1513069 1 NC_015844.1 Vanadium-dependent Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen peroxide forming dioxygen. They are likely to participate in the biosynthesis of halogenated natural products, such as volatile halogenated hydrocarbons, chiral halogenated terpenes, acetogenins and indoles; Lipoprotein signal peptide cleaved between the residues 16 and 17; localized in the outer membrane; Specificity unclear; vanadium-dependent haloperoxidase 1513069 10974265 zobellia_1262 Zobellia galactanivorans vanadium-dependent haloperoxidase YP_004735706.1 1511717 D 63186 CDS YP_004735707.1 340617254 10974266 1513076..1513975 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1513975 10974266 zobellia_1263 Zobellia galactanivorans membrane protein YP_004735707.1 1513076 D 63186 CDS YP_004735708.1 340617255 10974267 1514014..1514880 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1514880 10974267 zobellia_1264 Zobellia galactanivorans lipoprotein YP_004735708.1 1514014 D 63186 CDS YP_004735709.1 340617256 10974268 complement(1514888..1518640) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 30 and 31; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1518640 10974268 zobellia_1265 Zobellia galactanivorans lipoprotein YP_004735709.1 1514888 R 63186 CDS YP_004735710.1 340617257 10974269 1518653..1519855 1 NC_015844.1 Contains three C-terminal transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1519855 10974269 zobellia_1266 Zobellia galactanivorans membrane protein YP_004735710.1 1518653 D 63186 CDS YP_004735711.1 340617258 10974270 complement(1519852..1522233) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1522233 10974270 zobellia_1267 Zobellia galactanivorans hypothetical protein YP_004735711.1 1519852 R 63186 CDS YP_004735712.1 340617259 10974271 1522347..1523249 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1523249 10974271 zobellia_1268 Zobellia galactanivorans hypothetical protein YP_004735712.1 1522347 D 63186 CDS YP_004735713.1 340617260 10974272 1523295..1523945 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1523945 10974272 zobellia_1269 Zobellia galactanivorans hypothetical protein YP_004735713.1 1523295 D 63186 CDS YP_004735714.1 340617261 10974273 1524139..1525566 1 NC_015844.1 Conserved protein belonging to the DUF1593 family; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space and possibly secreted; Family membership; periplasmic protein 1525566 10974273 zobellia_1270 Zobellia galactanivorans periplasmic protein YP_004735714.1 1524139 D 63186 CDS YP_004735715.1 340617262 10974275 1525688..1526092 1 NC_015844.1 Conserved protein belonging to the OsmC family possibly involved in the response to stress; Localized in the cytoplasm; Family membership; OsmC-like protein 1526092 10974275 zobellia_1271 Zobellia galactanivorans OsmC-like protein YP_004735715.1 1525688 D 63186 CDS YP_004735716.1 340617263 10974276 1526163..1527041 1 NC_015844.1 Glycoside hydrolases hydrolyse the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non-carbohydrate moiety. Belongs to the family 114 of the glycoside hydrolases. Family GH114 contains endo-alpha-1,4-polygalactosaminidases, but the specificity of this protein is unclear. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 29 and 30. Localized in the outer membrane.; Specificity unclear; glycoside hydrolase 1527041 10974276 zobellia_1272 Zobellia galactanivorans glycoside hydrolase YP_004735716.1 1526163 D 63186 CDS YP_004735717.1 340617264 10974277 1527113..1527892 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1527892 10974277 zobellia_1273 Zobellia galactanivorans hypothetical protein YP_004735717.1 1527113 D 63186 CDS YP_004735718.1 340617265 10974278 1527882..1528268 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1528268 10974278 zobellia_1274 Zobellia galactanivorans hypothetical protein YP_004735718.1 1527882 D 63186 CDS YP_004735719.1 340617266 10974279 1528570..1529703 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains an N- terminal PAS/PAC domain involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 1529703 10974279 zobellia_1275 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004735719.1 1528570 D 63186 CDS YP_004735720.1 340617267 10974280 1529783..1530418 1 NC_015844.1 The Crp/Fnr-type transcriptional regulators complexe with cyclic AMP and bind to operator sites near the promoter with a C-terminal HTH domain to regulate the transcription of several catabolite-sensitive operons; They predominantly act as transcription activators, but can also be important repressors, and respond to diverse intracellular and exogenous signals; Localized in the cytoplasm; Family membership; Crp/Fnr-type transcriptional regulator 1530418 10974280 zobellia_1276 Zobellia galactanivorans Crp/Fnr-type transcriptional regulator YP_004735720.1 1529783 D 63186 CDS YP_004735721.1 340617268 10974281 1530485..1531414 1 NC_015844.1 Conserved protein highly Belongs to the Fe(II)-containing member of the Cupin superfamily; Localized in the cytoplasm.; Function unclear; Pirin-like protein 1531414 10974281 zobellia_1277 Zobellia galactanivorans Pirin-like protein YP_004735721.1 1530485 D 63186 CDS YP_004735722.1 340617269 10974282 1531420..1531623 1 NC_015844.1 Conserved protein belonging to the DUF1271 family. Members of this family contain three highly conserved cysteine residues. The function of this family is unknown. Localized in the cytoplasm.; Family membership; hypothetical protein 1531623 10974282 zobellia_1278 Zobellia galactanivorans hypothetical protein YP_004735722.1 1531420 D 63186 CDS YP_004735723.1 340617270 10974283 1531848..1532249 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1532249 10974283 zobellia_1279 Zobellia galactanivorans hypothetical protein YP_004735723.1 1531848 D 63186 CDS YP_004735724.1 340617271 10974284 1532356..1533672 1 NC_015844.1 GntT is part of the gluconate utilization system Gnt-I. It is a permease responsible for high-affinity intake of gluconate; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; high-affinity gluconate transporter 1533672 gntT2 10974284 gntT2 Zobellia galactanivorans high-affinity gluconate transporter YP_004735724.1 1532356 D 63186 CDS YP_004735725.1 340617272 10977944 1533688..1534443 1 NC_015844.1 Conserved protein belonging to the GDSL Lipase family, which includes a variety of lipolytic enzymes with serine as part of the active site; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Family membership; GDSL-like Lipase 1534443 10977944 zobellia_1281 Zobellia galactanivorans GDSL-like Lipase YP_004735725.1 1533688 D 63186 CDS YP_004735726.1 340617273 10974285 1534505..1535158 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1535158 10974285 zobellia_1282 Zobellia galactanivorans periplasmic protein YP_004735726.1 1534505 D 63186 CDS YP_004735727.1 340617274 10974286 complement(1535161..1537341) 1 NC_015844.1 Glutaryl-7-aminocephalosporanic-acid acylase, also known as cephalosporin acylase (CA), hydrolyzes the (7R)-7-(4-carboxybutanamido)cephalosporanate to (7R)-7-aminocephalosporanate and glutarate. The form catalytically active of CA, an alpha-beta dimer, is obtained by two proteolytic cleavages; Belongs to the family S45 of the serine peptidases; Contains an uncleavable signal peptide; Localized into the cytoplasmic membrane.; High confidence in function and specificity; glutaryl-7-aminocephalosporanic-acid acylase 1537341 10974286 zobellia_1283 Zobellia galactanivorans glutaryl-7-aminocephalosporanic-acid acylase YP_004735727.1 1535161 R 63186 CDS YP_004735728.1 340617275 10974287 complement(1537387..1538430) 1 NC_015844.1 Conserved protein belonging to the DUF477 family; Contains three transmembrane helices in the C-terminal region; Signal peptide cleaved between the residues 19 and 20; Localized in the cytoplasmic membrane; Family membership; membrane protein 1538430 10974287 zobellia_1284 Zobellia galactanivorans membrane protein YP_004735728.1 1537387 R 63186 CDS YP_004735729.1 340617276 10974288 1538558..1540294 1 NC_015844.1 The ABC-1 type transporters have their ABC membrane domain and their ABC ATPase domain fused in the same protein. They are involved in the efflux of compounds across the biological membranes or in targeting of membrane components; Contains six N-terminal transmembrane segments (ABC membrane) that form a pore in the cytoplasmic membrane an a C-terminal ATP-binding domain (ABC ATPase) responsible for energy generation; Belongs to the ABC-1 type transporter permease/ATP-binding family, lipid exporter subfamily (msbA subfamily); Family membership; ABC-1 type exporter ATP-binding/permease protein 1540294 10974288 zobellia_1285 Zobellia galactanivorans ABC-1 type exporter ATP-binding/permease protein YP_004735729.1 1538558 D 63186 CDS YP_004735730.1 340617277 10974289 complement(1540291..1540620) 1 NC_015844.1 Ferredoxins are electron carrier proteins with an iron-sulfur as cofactor and that transfer electrons in a wide variety of metabolic reactions. Belongs to the putidaredoxin, terpredoxin and adrenodoxin sub-family and uses 2Fe-2S cluster as cofactor ligated at four conserved cysteine residues. The general core structure consists of beta(2)-alpha-beta(2). Localized in the cytoplasm.; High confidence in function and specificity; 2Fe-2S ferredoxin 1540620 fdxA1 10974289 fdxA1 Zobellia galactanivorans 2Fe-2S ferredoxin YP_004735730.1 1540291 R 63186 CDS YP_004735731.1 340617278 10977824 complement(1540672..1541016) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1541016 10977824 zobellia_1287 Zobellia galactanivorans hypothetical protein YP_004735731.1 1540672 R 63186 CDS YP_004735732.1 340617279 10974290 complement(1541066..1542124) 1 NC_015844.1 This Enzyme is a class-2 pyridine nucleotide-disulphide reductases (PNDR). The active site is a redox-active disulfide bond. It uses the FAD to shuttle reducing equivalents from NAD(P)H to a Cys residue that is usually a part of a redox-active disulphide bridge. In a second step, the reduced disulphide reduces the substrate; Acts as an homodimer and binds one FAD molecule per subunit; Localized in the cytoplasm; High confidence in function and specificity; thioredoxin reductase 1542124 trxB2 10974290 trxB2 Zobellia galactanivorans thioredoxin reductase YP_004735732.1 1541066 R 63186 CDS YP_004735733.1 340617280 10978710 complement(1542196..1542435) 1 NC_015844.1 Conserved protein displaying similarity with the C-terminal domain of the Nitrogen fixation protein nifU. This latter protein is involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. Localized in the cytoplasm.; Family membership; NifU family protein 1542435 10978710 zobellia_1289 Zobellia galactanivorans NifU family protein YP_004735733.1 1542196 R 63186 CDS YP_004735734.1 340617281 10974291 complement(1542437..1543576) 1 NC_015844.1 The exact function of the protein mrp is still unknown. But mrp is homologous to the P loop NTPase Nbp35 from Saccharomyces cerevisiae, which is involved in the assembly of Fe/S proteins; Localized in the cytoplasm; Function unclear; protein mrp 1543576 mrpA 10974291 mrpA Zobellia galactanivorans protein mrp YP_004735734.1 1542437 R 63186 CDS YP_004735735.1 340617282 10978189 complement(1543833..1544177) 1 NC_015844.1 Atl1 acts as a DNA damage recognition factor. It is required for DNA repair from mutagenic O(6)-alkylguanine adducts. Binds O(6)-alkylguanine lesions providing a signal for other DNA repair pathways. Localized in the cytoplasm.; High confidence in function and specificity; alkyltransferase-like protein 1 1544177 atl1 10978189 atl1 Zobellia galactanivorans alkyltransferase-like protein 1 YP_004735735.1 1543833 R 63186 CDS YP_004735736.1 340617283 10977566 complement(1544177..1544806) 1 NC_015844.1 Protein that consists of a LysE type translocator domain with six transmembrane segments; Probably localized in the cytoplasmic memmbrane; hypothetical protein 1544806 10977566 zobellia_1292 Zobellia galactanivorans hypothetical protein YP_004735736.1 1544177 R 63186 CDS YP_004735737.1 340617284 10974293 complement(1544809..1545477) 1 NC_015844.1 tRNA (guanine-N(7)-)-methyltransferase is involved in tRNA maturation. It catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. Localized in the cytoplasm.; High confidence in function and specificity; tRNA (guanine-N(7)-)-methyltransferase 1545477 trmB 10974293 trmB Zobellia galactanivorans tRNA (guanine-N(7)-)-methyltransferase YP_004735737.1 1544809 R 63186 CDS YP_004735738.1 340617285 10978687 complement(1545488..1546564) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two transmembrane segments; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 1546564 10978687 zobellia_1294 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004735738.1 1545488 R 63186 CDS YP_004735739.1 340617286 10974294 complement(1546702..1547388) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity (here, a winged-helix DNA-binding domain) that acts as transcriptional regulator; Family membership; two-component system-response regulator 1547388 10974294 zobellia_1295 Zobellia galactanivorans two-component system-response regulator YP_004735739.1 1546702 R 63186 CDS YP_004735740.1 340617287 10974295 1547594..1549996 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 26 and 27; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1549996 10974295 zobellia_1296 Zobellia galactanivorans lipoprotein YP_004735740.1 1547594 D 63186 CDS YP_004735741.1 340617288 10974296 1550102..1552918 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations. Contains a carboxypeptidase regulatory domain (22-102) and the Plug module (125-228) acting as a channel gate. The signal peptide is cleaved between the residues 19 and 20.; Family membership; TonB-dependent receptor 1552918 10974296 zobellia_1297 Zobellia galactanivorans TonB-dependent receptor YP_004735741.1 1550102 D 63186 CDS YP_004735742.1 340617289 10974297 1553206..1553514 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1553514 10974297 zobellia_1298 Zobellia galactanivorans periplasmic protein YP_004735742.1 1553206 D 63186 CDS YP_004735743.1 340617290 10974298 1553735..1554058 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1554058 10974298 zobellia_1299 Zobellia galactanivorans periplasmic protein YP_004735743.1 1553735 D 63186 CDS YP_004735744.1 340617291 10974299 complement(1554157..1554588) 1 NC_015844.1 Peptidyl-prolyl cis-trans isomerase, or PPIase or rotamase, accelerates the folding of proteins. It catalyzes the peptidyl-prolyl isomerisation during which the peptide bond preceding proline (the peptidyl-prolyl bond) is stabilised in the cis conformation in oligopeptides; Localized in the cytoplasm; High confidence in function and specificity; FKBP-type peptidyl-prolyl cis-trans isomerase 2 1554588 fkpB 10974299 fkpB Zobellia galactanivorans FKBP-type peptidyl-prolyl cis-trans isomerase 2 YP_004735744.1 1554157 R 63186 CDS YP_004735745.1 340617292 10977833 1554859..1555836 1 NC_015844.1 Hypothetical protein that contains a N-terminal LuxE domain; Localized in the cytoplasm; hypothetical protein 1555836 10977833 zobellia_1301 Zobellia galactanivorans hypothetical protein YP_004735745.1 1554859 D 63186 CDS YP_004735746.1 340617293 10974300 complement(1555833..1556363) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1556363 10974300 zobellia_1302 Zobellia galactanivorans hypothetical protein YP_004735746.1 1555833 R 63186 CDS YP_004735747.1 340617294 10974301 complement(1556449..1557744) 1 NC_015844.1 Tyrosyl-tRNA synthetase catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). Belongs to the class I of the aminoacyl-tRNA synthetases. Localized in the cytoplasm.; High confidence in function and specificity; tyrosyl-tRNA synthetase 1557744 tyrS 10974301 tyrS Zobellia galactanivorans tyrosyl-tRNA synthetase YP_004735747.1 1556449 R 63186 CDS YP_004735748.1 340617295 10978719 1557849..1558856 1 NC_015844.1 The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions and NAD as a cofactor; Belongs to the NAD-dependent epimerase/dehydratase family, Rossmann fold Superfamily; Localized in the cytoplasm; Family membership; NAD-dependent epimerase/dehydratase family protein 1558856 10978719 zobellia_1304 Zobellia galactanivorans NAD-dependent epimerase/dehydratase family protein YP_004735748.1 1557849 D 63186 CDS YP_004735749.1 340617296 10974302 complement(1558837..1559235) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1559235 10974302 zobellia_1305 Zobellia galactanivorans hypothetical protein YP_004735749.1 1558837 R 63186 CDS YP_004735750.1 340617297 10974303 complement(1559261..1560595) 1 NC_015844.1 Allantoinase is involved in purine metabolism. It catalyzes the reaction: (S)-allantoin + H2O = allantoate. Binds one zinc ion. Localized in the cytoplasm.; High confidence in function and specificity; allantoinase 1560595 pucH 10974303 pucH Zobellia galactanivorans allantoinase YP_004735750.1 1559261 R 63186 CDS YP_004735751.1 340617298 10978401 complement(1560597..1561325) 1 NC_015844.1 Polyprenol phosphate mannose synthase catalyses the transfer of mannose from GDP-mannose to polyprenol phosphate. Polyprenol phosphate mannose is a sugar donor; Belongs to the family 2 of the glycosyltransferases (GT2); Localized in the cytoplasm; High confidence in function and specificity; polyprenol phosphate mannose synthase 1561325 ppmA 10978401 ppmA Zobellia galactanivorans polyprenol phosphate mannose synthase YP_004735751.1 1560597 R 63186 CDS YP_004735752.1 340617299 10978375 1561488..1563155 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 83 of the glycosyltransferases. Displays also a C-terminal module of unknown function. Features nine N-terminal transmembrane helices. Localized in the cytoplasmic membrane.; Specificity unclear; glycosyltransferase 1563155 10978375 zobellia_1308 Zobellia galactanivorans glycosyltransferase YP_004735752.1 1561488 D 63186 CDS YP_004735753.1 340617300 10974304 1563156..1563812 1 NC_015844.1 Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1563812 10974304 zobellia_1309 Zobellia galactanivorans membrane protein YP_004735753.1 1563156 D 63186 CDS YP_004735754.1 340617301 10974305 1563819..1564565 1 NC_015844.1 Uroporphyrinogen-III synthase is the fourth enzyme in the heme biosynthesis pathway. It catalyzes the reaction: hydroxymethylbilane = uroporphyrinogen III + H2O. Localized in the cytoplasm.; High confidence in function and specificity; uroporphyrinogen-III synthase 1564565 hemD 10974305 hemD Zobellia galactanivorans uroporphyrinogen-III synthase YP_004735754.1 1563819 D 63186 CDS YP_004735755.1 340617302 10977966 complement(1564648..1566246) 1 NC_015844.1 Phosphoenolpyruvate carboxykinase (ATP) (PEPCK) catalyzes the formation of phosphoenolpyruvate by decarboxylation of oxaloacetate while hydrolyzing ATP, a rate limiting step in gluconeogenesis. PEPCK is allosterically activated by calcium and positively regulated by cAMP. It is involved in the glyoxylate bypass, an alternative to the tricarboxylic acid cycle; Localized in the cytoplasm; High confidence in function and specificity; phosphoenolpyruvate carboxykinase 1566246 pckA2 10977966 pckA2 Zobellia galactanivorans phosphoenolpyruvate carboxykinase YP_004735755.1 1564648 R 63186 CDS YP_004735756.1 340617303 10978313 complement(1566332..1566718) 1 NC_015844.1 Protein containing a domain of unknown function DUF423 and Features four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1566718 10978313 zobellia_1312 Zobellia galactanivorans membrane protein YP_004735756.1 1566332 R 63186 CDS YP_004735757.1 340617304 10974307 1566800..1568179 1 NC_015844.1 Saccharopine dehydrogenase is a homodimer that converts the N6-(L-1,3-dicarboxypropyl)-L-lysine to L-glutamate and L-2-aminoadipate 6-semialdehyde. Each subunit consists of three domains. Domain I contains a variant of the Rossmann fold that binds NADPH. Domain II, involved in substrate binding and dimer formation, folds into a mixed seven-stranded beta sheet flanked by alpha helices. Domain III is all-helical; Localized in the cytoplasm; High confidence in function and specificity; Saccharopine dehydrogenase 1568179 lys9 10974307 lys9 Zobellia galactanivorans Saccharopine dehydrogenase YP_004735757.1 1566800 D 63186 CDS YP_004735758.1 340617305 10978110 1568275..1568745 1 NC_015844.1 The transcriptional regulator AsnC is the activator of the asnA gene involved in the asparagine synthesis and is a autogenous regulator of its own transcription; Contains a N-terminal AsnC/Lrp-type HTH domain; Localized in the cytoplasm; High confidence in function and specificity; transcriptional regulator AsnC 1568745 asnC2 10978110 asnC2 Zobellia galactanivorans transcriptional regulator AsnC YP_004735758.1 1568275 D 63186 CDS YP_004735759.1 340617306 10977560 1568777..1569112 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 1569112 10977560 zobellia_1315 Zobellia galactanivorans hypothetical protein YP_004735759.1 1568777 D 63186 CDS YP_004735760.1 340617307 10974308 1569220..1569732 1 NC_015844.1 Ferritin stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. It forms a homo-oligomer of 24 subunits that assemble into a spherical protein shell (12 +/- 1 nM diameter) that can sequester at least 2000 iron atoms. Localized in the cytoplasm.; High confidence in function and specificity; ferritin 1569732 ftnA 10974308 ftnA Zobellia galactanivorans ferritin YP_004735760.1 1569220 D 63186 CDS YP_004735761.1 340617308 10977845 complement(1569807..1570502) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1570502 10977845 zobellia_1317 Zobellia galactanivorans membrane protein YP_004735761.1 1569807 R 63186 CDS YP_004735762.1 340617309 10974309 complement(1570713..1570967) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1570967 10974309 zobellia_1318 Zobellia galactanivorans membrane protein YP_004735762.1 1570713 R 63186 CDS YP_004735763.1 340617310 10974310 complement(1570995..1573931) 1 NC_015844.1 Leucyl-tRNA synthetase catalyses the attachment of leucine to its cognate transfer RNA molecule in a highly specific two-step reaction. Belongs to the class I of the aminoacyl-tRNA synthetases. It is a monomer and adopts a Rossmann fold. Localized in the cytoplasm.; High confidence in function and specificity; Leucyl-tRNA synthetase 1573931 leuS 10974310 leuS Zobellia galactanivorans Leucyl-tRNA synthetase YP_004735763.1 1570995 R 63186 CDS YP_004735764.1 340617311 10978086 1574012..1574890 1 NC_015844.1 Possible permease of unknown function essential for cell division. FtsX may function as part of a translocation apparatus that inserts proteins involved in cell division and proteins involved in gliding motility into the cytoplasmic membrane; Contains one N-terminal transmembrane segment and three C-terminal transmembrane segments; Localized in the cytoplasmic membrane; Function unclear; cell division protein FtsX 1574890 ftsX 10978086 ftsX Zobellia galactanivorans cell division protein FtsX YP_004735764.1 1574012 D 63186 CDS YP_004735765.1 340617312 10977853 1574979..1575248 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1575248 10977853 zobellia_1321 Zobellia galactanivorans membrane protein YP_004735765.1 1574979 D 63186 CDS YP_004735766.1 340617313 10974312 1575250..1576044 1 NC_015844.1 Undecaprenyl-diphosphatase, as known as Bacitracin resistance protein, catalyzes the dephosphorylation of undecaprenyl diphosphate. Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available. Features six transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; UDP-diphosphatase 1576044 uppP 10974312 uppP Zobellia galactanivorans UDP-diphosphatase YP_004735766.1 1575250 D 63186 CDS YP_004735767.1 340617314 10978729 1576087..1576800 1 NC_015844.1 TruB is responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. It catalyzes the reaction: tRNA uridine = tRNA pseudouridine. Localized in the cytoplasm.; High confidence in function and specificity; tRNA pseudouridine synthase B 1576800 truB 10978729 truB Zobellia galactanivorans tRNA pseudouridine synthase B YP_004735767.1 1576087 D 63186 CDS YP_004735768.1 340617315 10978703 1576870..1577601 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1577601 10978703 zobellia_1324 Zobellia galactanivorans periplasmic protein YP_004735768.1 1576870 D 63186 CDS YP_004735769.1 340617316 10974313 complement(1577578..1578204) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1578204 10974313 zobellia_1325 Zobellia galactanivorans hypothetical protein YP_004735769.1 1577578 R 63186 CDS YP_004735770.1 340617317 10974314 1578523..1579086 1 NC_015844.1 DNA-3-methyladenine glycosylase catalyzes the hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions. The reaction releases a free base and leaves an apurinic site. Localized in the cytoplasm.; High confidence in function and specificity; DNA-3-methyladenine glycosylase 1579086 tag 10974314 tag Zobellia galactanivorans DNA-3-methyladenine glycosylase YP_004735770.1 1578523 D 63186 CDS YP_004735771.1 340617318 10978635 1579120..1579710 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1579710 10978635 zobellia_1327 Zobellia galactanivorans periplasmic protein YP_004735771.1 1579120 D 63186 CDS YP_004735772.1 340617319 10974315 1579691..1580377 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1580377 10974315 zobellia_1328 Zobellia galactanivorans lipoprotein YP_004735772.1 1579691 D 63186 CDS YP_004735773.1 340617320 10974316 complement(1580348..1581028) 1 NC_015844.1 Leucyl/phenylalanyl-tRNA--protein transferase transfers a Leu or Phe to the amino end of certain proteins to enable degradation. The N-terminal residue controls the biological half-life of many proteins via the N-end rule pathway.; High confidence in function and specificity; Leucyl/phenylalanyl-tRNA--protein transferase 1581028 aatA 10974316 aatA Zobellia galactanivorans Leucyl/phenylalanyl-tRNA--protein transferase YP_004735773.1 1580348 R 63186 CDS YP_004735774.1 340617321 10977455 complement(1581136..1581513) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1581513 10977455 zobellia_1330 Zobellia galactanivorans hypothetical protein YP_004735774.1 1581136 R 63186 CDS YP_004735775.1 340617322 10974317 complement(1581615..1582280) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Could be localized in the outer membrane; Conserved hypothetical protein; membrane protein 1582280 10974317 zobellia_1331 Zobellia galactanivorans membrane protein YP_004735775.1 1581615 R 63186 CDS YP_004735776.1 340617323 10974318 complement(1582368..1583252) 1 NC_015844.1 The flavoredoxins are a group of proteins with a tightly bound flavin mononucleotide (FMN) that mediate electron transfer at low redox potential producing reduced flavin for various biological processes; Some flavin reductases function in a two-component enzyme system; Contains a FMN-binding split barrel; Specificity unclear; putative flavoredoxin 1583252 10974318 zobellia_1332 Zobellia galactanivorans putative flavoredoxin YP_004735776.1 1582368 R 63186 CDS YP_004735777.1 340617324 10974319 1583391..1584545 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two transmembrane segments; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 1584545 10974319 zobellia_1333 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004735777.1 1583391 D 63186 CDS YP_004735778.1 340617325 10974320 1584631..1584978 1 NC_015844.1 Contains a C-terminal transmembrane segment; Probably localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1584978 10974320 zobellia_1334 Zobellia galactanivorans hypothetical protein YP_004735778.1 1584631 D 63186 CDS YP_004735779.1 340617326 10974321 complement(1584975..1585367) 1 NC_015844.1 Conserved protein belonging to the Histidine Triad (HIT) family, which includes nucleotide-binding proteins; Localized in the cytoplasm; Family membership; HIT family protein 1585367 10974321 zobellia_1335 Zobellia galactanivorans HIT family protein YP_004735779.1 1584975 R 63186 CDS YP_004735780.1 340617327 10974322 complement(1585382..1585858) 1 NC_015844.1 GreA is necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by GreA allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides; Belongs to the greA/greB family; Localized in the cytoplasm; High confidence in function and specificity; transcription elongation factor GreA 1585858 greA 10974322 greA Zobellia galactanivorans transcription elongation factor GreA YP_004735780.1 1585382 R 63186 CDS YP_004735781.1 340617328 10977950 1586005..1586442 1 NC_015844.1 Signal peptide of lipoprotein cleaved between the residues 15 and 16; localized in the outer membrane; Hypothetical protein; hypothetical protein 1586442 10977950 zobellia_1337 Zobellia galactanivorans hypothetical protein YP_004735781.1 1586005 D 63186 CDS YP_004735782.1 340617329 10974323 complement(1586448..1587131) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1587131 10974323 zobellia_1338 Zobellia galactanivorans hypothetical protein YP_004735782.1 1586448 R 63186 CDS YP_004735783.1 340617330 10974324 complement(1587164..1588141) 1 NC_015844.1 NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold; Localized in the cytoplasm; Specificity unclear; NAD(P)-dependent oxidoreductase 1588141 10974324 zobellia_1339 Zobellia galactanivorans NAD(P)-dependent oxidoreductase YP_004735783.1 1587164 R 63186 CDS YP_004735784.1 340617331 10974325 complement(1588275..1590407) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Does not contain of carboxypeptidase regulatory domain; Contains the Plug module (44-155) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 1590407 10974325 zobellia_1340 Zobellia galactanivorans TonB-dependent Receptor YP_004735784.1 1588275 R 63186 CDS YP_004735785.1 340617332 10974327 complement(1590530..1590664) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1590664 10974327 zobellia_1341 Zobellia galactanivorans hypothetical protein YP_004735785.1 1590530 R 63186 CDS YP_004735786.1 340617333 10974328 1590796..1593276 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. The cytoplasmic part of the protein consists of the histidine kinase domain, the receiver domain of the response regulator that is phosphorylated by the histidine kinase domain and an histidine-containing Phosphotransfer (HPt) domain. A transmembrane segment separates this part from the periplasmic part that contains no particular domains; Localized in the cytoplasmic membrane; Family membership; two-component system hybrid-sensor histidine kinase/response regulator, receiver domain 1593276 10974328 zobellia_1342 Zobellia galactanivorans two-component system hybrid-sensor histidine kinase/response regulator, receiver domain YP_004735786.1 1590796 D 63186 CDS YP_004735787.1 340617334 10974329 complement(1593251..1594633) 1 NC_015844.1 These response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes, activating the expression of genes from promoters recognized by core RNA polymerase associated with the alternative sigma-54 factor. This protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, a motif that interacts with the sigma 54 factor and a C-terminal Fis-type HTH motif; Family membership; sigma-54 dependent two-component system-response regulator 1594633 10974329 zobellia_1343 Zobellia galactanivorans sigma-54 dependent two-component system-response regulator YP_004735787.1 1593251 R 63186 CDS YP_004735788.1 340617335 10974330 complement(1594812..1595117) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein; periplasmic protein 1595117 10974330 zobellia_1344 Zobellia galactanivorans periplasmic protein YP_004735788.1 1594812 R 63186 CDS YP_004735789.1 340617336 10974331 complement(1595191..1595496) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1595496 10974331 zobellia_1345 Zobellia galactanivorans periplasmic protein YP_004735789.1 1595191 R 63186 CDS YP_004735790.1 340617337 10974332 complement(1596002..1596307) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1596307 10974332 zobellia_1346 Zobellia galactanivorans periplasmic protein YP_004735790.1 1596002 R 63186 CDS YP_004735791.1 340617338 10974333 complement(1596640..1596948) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1596948 10974333 zobellia_1347 Zobellia galactanivorans periplasmic protein YP_004735791.1 1596640 R 63186 CDS YP_004735792.1 340617339 10974334 complement(1597183..1598721) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1598721 10974334 zobellia_1348 Zobellia galactanivorans hypothetical protein YP_004735792.1 1597183 R 63186 CDS YP_004735793.1 340617340 10974335 complement(1598718..1599191) 1 NC_015844.1 Protein that displays similarity with the C-terminal region of the transcriptional regulator nadR; Localized in the cytoplasm; hypothetical protein 1599191 10974335 zobellia_1349 Zobellia galactanivorans hypothetical protein YP_004735793.1 1598718 R 63186 CDS YP_004735794.1 340617341 10974336 complement(1599239..1599877) 1 NC_015844.1 PnuC is a membrane protein responsible for nicotinamide mononucleotide transport; Contains seven transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; Nicotinamide mononucleotide transporter 1599877 pnuC1 10974336 pnuC1 Zobellia galactanivorans Nicotinamide mononucleotide transporter YP_004735794.1 1599239 R 63186 CDS YP_004735795.1 340617342 10978358 complement(1599861..1600121) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1600121 10978358 zobellia_1351 Zobellia galactanivorans hypothetical protein YP_004735795.1 1599861 R 63186 CDS YP_004735796.1 340617343 10974338 complement(1600223..1600855) 1 NC_015844.1 Conserved protein belonging to the 4'-phosphopantetheinyl transferase family; The members of this family activates enzymes and carrier proteins, by transferring the phophopantethiene prosthetic group of coenzyme A to its attachment site (a serine residue). Many members of the family are small proteins that act on the acyl carrier protein involved in fatty acid biosynthesis; Uses magnesium ion as cofactor; Localized in the cytoplasm; Family membership; 4'-phosphopantetheinyl transferase family protein 1600855 10974338 zobellia_1352 Zobellia galactanivorans 4'-phosphopantetheinyl transferase family protein YP_004735796.1 1600223 R 63186 CDS YP_004735797.1 340617344 10974339 1600938..1602254 1 NC_015844.1 Adenosylhomocysteinase is an enzyme of the activated methyl cycle, responsible for the reversible hydration of S-adenosyl-L-homocysteine into adenosine and homocysteine. AdoHcyase is an ubiquitous enzyme which binds and requires NAD+ as a cofactor. Localized in the cytoplasm.; High confidence in function and specificity; adenosylhomocysteinase 1602254 ahcY 10974339 ahcY Zobellia galactanivorans adenosylhomocysteinase YP_004735797.1 1600938 D 63186 CDS YP_004735798.1 340617345 10977487 complement(1602451..1603467) 1 NC_015844.1 3-Phytase, also known as myo-inositol-hexaphosphate 3-phosphohydrolase, catalyzes the hydrolysis of inorganic orthophosphate from phytate. It uses calcium ion as cofactor. Adopts a six- bladed beta propeller fold. Contains a prokaryotic lipoprotein signal peptide cleaved between 16 and 17; Localized in the outer membrane; High confidence in function and specificity; 3-Phytase 1603467 phyC 10977487 phyC Zobellia galactanivorans 3-Phytase YP_004735798.1 1602451 R 63186 CDS YP_004735799.1 340617346 10978352 complement(1603526..1606390) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations. Contains a carboxypeptidase regulatory domain (28-107) and the Plug module (129-236) acting as a channel gate. The signal peptide is cleaved between the residues 25 and 26.; Family membership; TonB-dependent Receptor 1606390 10978352 zobellia_1355 Zobellia galactanivorans TonB-dependent Receptor YP_004735799.1 1603526 R 63186 CDS YP_004735800.1 340617347 10974340 complement(1606546..1607874) 1 NC_015844.1 Conserved protein containing five N-terminal tetratrico peptide repeats (TPRs), a central transmembrane helix and a C-terminal domain of unknown function. TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Localized in the cytoplasmic membrane; Function unclear; hypothetical protein 1607874 10974340 zobellia_1356 Zobellia galactanivorans hypothetical protein YP_004735800.1 1606546 R 63186 CDS YP_004735801.1 340617348 10974341 complement(1607907..1608035) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1608035 10974341 zobellia_1357 Zobellia galactanivorans hypothetical protein YP_004735801.1 1607907 R 63186 CDS YP_004735802.1 340617349 10974342 complement(1608188..1608448) 1 NC_015844.1 Ribosomal protein L27 is part of the large ribosomal subunit (50S). It cross-links to the 23S rRNA and to the A and P site tRNAs. RpmA is essential for ribosome function, but its exact role is unclear; Belongs to the ribosomal protein L27p family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L27 1608448 rpmA 10974342 rpmA Zobellia galactanivorans 50S ribosomal protein L27 YP_004735802.1 1608188 R 63186 CDS YP_004735803.1 340617350 10978516 complement(1608531..1609175) 1 NC_015844.1 Ribosomal protein L21 is part of the large ribosomal subunit (50S). It binds to 23S rRNA in the presence of protein L20; Contains an domain C-terminal of 100 residues harbouring an Helix-hairpin-helix (HhH) motif involved in non-sequence-specific DNA binding. The function of this domain is unknown; Belongs to the ribosomal protein L21p family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L21 1609175 rplU 10978516 rplU Zobellia galactanivorans 50S ribosomal protein L21 YP_004735803.1 1608531 R 63186 CDS YP_004735804.1 340617351 10978511 complement(1609361..1609825) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1609825 10978511 zobellia_1360 Zobellia galactanivorans membrane protein YP_004735804.1 1609361 R 63186 CDS YP_004735805.1 340617352 10974344 1609996..1611318 1 NC_015844.1 Peptidase family M16 contains metalloendopeptidases. Two of the zinc ligands occur in the motif His-Xaa-Xaa-Glu-His. The glutamate in this HXXEH motif is important for catalysis, and a glutamate more C- terminal is the third zinc ligand. Features a signal peptide cleaved between the residues 20 and 21. Localized in the periplasm.; Specificity unclear; metallopeptidase 6 1611318 10974344 zobellia_1361 Zobellia galactanivorans metallopeptidase 6 YP_004735805.1 1609996 D 63186 CDS YP_004735806.1 340617353 10974345 1611380..1613449 1 NC_015844.1 This protein belongs to the family 16 of the metallopeptidase, but the catalytic motif His-Xaa-Xaa-Glu-His (zinc-binding) is missing. This protein also displays a conserved C-terminal domain of unknown function. Features a signal peptide cleaved between the residues 19 and 20. Localized in the periplasm.; Function unclear; family M16 non-peptidase protein 1613449 10974345 zobellia_1362 Zobellia galactanivorans family M16 non-peptidase protein YP_004735806.1 1611380 D 63186 CDS YP_004735807.1 340617354 10974346 complement(1613610..1614725) 1 NC_015844.1 IrpA occurs under iron-deficient growth conditions and disappears in cells recovering from iron starvation. It seems to be involved in iron acquisition, uptake or storage; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 26 and 25; Localized in the cytoplasmic and/or outer membrane; Function unclear; iron-regulated protein A 1614725 irpA1 10974346 irpA1 Zobellia galactanivorans iron-regulated protein A YP_004735807.1 1613610 R 63186 CDS YP_004735808.1 340617355 10978042 complement(1614730..1616154) 1 NC_015844.1 Protein containing two Cytochrome c domains. Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes; Contains a heme as prostetic group and a prokaryotic lipoprotein signal peptide cleaved between the residues 29 and 30; Localized in the outer membrane; Function unclear; cytochrome c-containing protein 1616154 10978042 zobellia_1364 Zobellia galactanivorans cytochrome c-containing protein YP_004735808.1 1614730 R 63186 CDS YP_004735809.1 340617356 10974347 complement(1616224..1617399) 1 NC_015844.1 IrpA occurs under iron-deficient growth conditions and disappears in cells recovering from iron starvation. It seems to be involved in iron acquisition, uptake or storage; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Function unclear; iron-regulated protein A 1617399 irpA2 10974347 irpA2 Zobellia galactanivorans iron-regulated protein A YP_004735809.1 1616224 R 63186 CDS YP_004735810.1 340617357 10978043 complement(1617560..1618435) 1 NC_015844.1 Conserved membrane protein belonging to the DUF6 family; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 1618435 10978043 zobellia_1366 Zobellia galactanivorans membrane protein YP_004735810.1 1617560 R 63186 CDS YP_004735811.1 340617358 10974348 1618637..1619047 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 1619047 10974348 zobellia_1367 Zobellia galactanivorans membrane protein YP_004735811.1 1618637 D 63186 CDS YP_004735812.1 340617359 10974349 1619150..1619578 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1619578 10974349 zobellia_1368 Zobellia galactanivorans periplasmic protein YP_004735812.1 1619150 D 63186 CDS YP_004735813.1 340617360 10974350 complement(1619610..1620164) 1 NC_015844.1 Lipoprotein involved in the gliding motility; Signal peptide cleaved between the residues 17 and 18; localized in the cytoplasmic membrane; Function unclear; gliding motility membrane lipoprotein 1620164 gldD 10974350 gldD Zobellia galactanivorans gliding motility membrane lipoprotein YP_004735813.1 1619610 R 63186 CDS YP_004735814.1 340617361 10977901 complement(1620151..1621470) 1 NC_015844.1 GldE probably is a transporter; Contains four N-terminal transmembrane segments, followed of two CBS domains (Bateman domain) that have been shown to bind ligands with an adenosyl group such as AMP, ATP or S-AdoMet and may regulate the activity of attached enzymatic or other domains. Contains a C-terminal HlyC/CorC-type transporter associated domain; Localized in the cytoplasmic membrane; Specificity unclear; gliding motility membrane protein 1621470 gldE 10977901 gldE Zobellia galactanivorans gliding motility membrane protein YP_004735814.1 1620151 R 63186 CDS YP_004735815.1 340617362 10977902 complement(1621641..1622105) 1 NC_015844.1 Single-stranded DNA-binding protein (SSB) is essential for replication of the chromosome. It is also involved in DNA recombination and repair. This protein forms a homotetramer. Localized in the cytoplasm.; High confidence in function and specificity; single-stranded DNA-binding protein 1622105 ssb1 10977902 ssb1 Zobellia galactanivorans single-stranded DNA-binding protein YP_004735815.1 1621641 R 63186 CDS YP_004735816.1 340617363 10978612 complement(1622238..1623284) 1 NC_015844.1 MutY is an adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past go lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine; 1 4Fe-4S cluster, not important for the catalytic activity, is present. This cluster is probably involved in the proper positioning of the enzyme along the DNA strand; Localized in the cytoplasm; High confidence in function and specificity; A/G-specific adenine glycosylase 1623284 mutY 10978612 mutY Zobellia galactanivorans A/G-specific adenine glycosylase YP_004735816.1 1622238 R 63186 CDS YP_004735817.1 340617364 10978215 complement(1623297..1623428) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1623428 10978215 zobellia_1373 Zobellia galactanivorans hypothetical protein YP_004735817.1 1623297 R 63186 CDS YP_004735818.1 340617365 10974352 1623464..1623754 1 NC_015844.1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. It forms a heterodimer of an alpha and a beta chain; Belongs to the bacterial histone-like protein family; localized in the cytoplasm.; High confidence in function and specificity; DNA-binding protein HU 1623754 hupA 10974352 hupA Zobellia galactanivorans DNA-binding protein HU YP_004735818.1 1623464 D 63186 CDS YP_004735819.1 340617366 10978003 1624053..1625600 1 NC_015844.1 Ribonuclease G is involved in the processing of the 5'-end of 16S rRNA. Could be involved in chromosome segregation and cell division. It may be one of the components of the cytoplasmic axial filaments bundles or merely regulate the formation of this structure; Contains a S1 motif domain; Belongs to the RNase E/G family, RNase G subfamily; Localized in the cytoplasm; High confidence in function and specificity; ribonuclease G 1625600 rngA 10978003 rngA Zobellia galactanivorans ribonuclease G YP_004735819.1 1624053 D 63186 CDS YP_004735820.1 340617367 10978480 1625734..1626207 1 NC_015844.1 Transcriptional regulator belonging to the RecX family. Localized in the cytoplasm.; Family membership; RecX-type transcriptional regulator 1626207 10978480 zobellia_1376 Zobellia galactanivorans RecX-type transcriptional regulator YP_004735820.1 1625734 D 63186 CDS YP_004735821.1 340617368 10974353 complement(1626221..1626718) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1626718 10974353 zobellia_1377 Zobellia galactanivorans periplasmic protein YP_004735821.1 1626221 R 63186 CDS YP_004735822.1 340617369 10974354 complement(1626756..1627616) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1627616 10974354 zobellia_1378 Zobellia galactanivorans hypothetical protein YP_004735822.1 1626756 R 63186 CDS YP_004735823.1 340617370 10974355 complement(1627693..1628787) 1 NC_015844.1 Biotin synthase works with flavodoxin, S-adenosylmethionine, and possibly cysteine to catalyze the last step of the biotin biosynthetic pathway. The reaction consists of the introduction of a sulphur atom into dethiobiotin, thus requiring activation of C-H bonds. It forms a homodimer and binds one 4Fe-4S cluster by subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Localized in the cytoplasm.; High confidence in function and specificity; biotin synthase 1628787 bioB 10974355 bioB Zobellia galactanivorans biotin synthase YP_004735823.1 1627693 R 63186 CDS YP_004735824.1 340617371 10977603 complement(1628928..1630364) 1 NC_015844.1 Conserved protein belonging to the Band 7 family. The band 7 protein is an integral membrane protein which is thought to regulate cation conductance; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Family membership; hypothetical protein 1630364 10977603 zobellia_1380 Zobellia galactanivorans hypothetical protein YP_004735824.1 1628928 R 63186 CDS YP_004735825.1 340617372 10974357 complement(1630369..1630947) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1630947 10974357 zobellia_1381 Zobellia galactanivorans membrane protein YP_004735825.1 1630369 R 63186 CDS YP_004735826.1 340617373 10974358 complement(1631020..1632207) 1 NC_015844.1 3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP synthase 1632207 fabB1 10974358 fabB1 Zobellia galactanivorans 3-oxoacyl-ACP synthase YP_004735826.1 1631020 R 63186 CDS YP_004735827.1 340617374 10977793 complement(1632217..1633518) 1 NC_015844.1 Enzyme that, in presence of S-adenosyl-L-methionine as donor, converts the 8-amino-7-oxononanoate to 7,8-diaminononanoate in the biotin anabolism; S-adenosylhomocysteine can also act as donor; Uses the Pyridoxal phosphate as cofactor linked to a conserved lysine residue; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 1633518 bioA 10977793 bioA Zobellia galactanivorans adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_004735827.1 1632217 R 63186 CDS YP_004735828.1 340617375 10977602 1633594..1635219 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; Belongs to the family 83 of the glycosyltransferases (GT83); Contains 11 transmembrane segments; Localized in the cytoplasmic membrane; Specificity unclear; glycosyltransferase 1635219 10977602 zobellia_1384 Zobellia galactanivorans glycosyltransferase YP_004735828.1 1633594 D 63186 CDS YP_004735829.1 340617376 10974359 complement(1635226..1635843) 1 NC_015844.1 Dethiobiotin synthetase is involved in biotin biosynthesis and catalyzes the reaction: CO2 + 7,8-diaminononanoate + ATP = dethiobiotin + phosphate + ADP. The enzyme binds ATP and requires magnesium as a co-factor. It forms a homodimer and is localized in the cytoplasm.; High confidence in function and specificity; Dethiobiotin synthetase 1635843 bioD 10974359 bioD Zobellia galactanivorans Dethiobiotin synthetase YP_004735829.1 1635226 R 63186 CDS YP_004735830.1 340617377 10977604 complement(1635845..1636228) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1636228 10977604 zobellia_1386 Zobellia galactanivorans hypothetical protein YP_004735830.1 1635845 R 63186 CDS YP_004735831.1 340617378 10974360 complement(1636230..1637381) 1 NC_015844.1 This enzyme catalyzes the 8-amino-7-oxononanoate formation used in the biotin biosynthesis. Uses the pyridoxal-phosphate as cofactor. Belongs to the class II of the pyridoxal-phosphate-dependent aminotransferases; Localized in the cytoplasm.; High confidence in function and specificity; 8-amino-7-oxononanoate synthase 1637381 bioF 10974360 bioF Zobellia galactanivorans 8-amino-7-oxononanoate synthase YP_004735831.1 1636230 R 63186 CDS YP_004735832.1 340617379 10977605 1637525..1639336 1 NC_015844.1 This metallopeptidase encompasses a N-terminal catalytic domain belonging to the family M61 and a C-terminal PDZ domain. The active site residues are located in an HEXXH motif. The conserved Glu, 30 residues to the C-terminus of the HEXXH motif, likely is the third zinc ligand. PDZ domain bind either the carboxyl-terminal sequences of proteins or internal peptide sequences. Features a signal peptide cleaved between residues 18 and 19. localized in the periplasm.; Specificity unclear; metallopeptidase 1639336 10977605 zobellia_1388 Zobellia galactanivorans metallopeptidase YP_004735832.1 1637525 D 63186 CDS YP_004735833.1 340617380 10974361 complement(1639802..1640053) 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1640053 10974361 zobellia_1389 Zobellia galactanivorans hypothetical protein YP_004735833.1 1639802 R 63186 CDS YP_004735834.1 340617381 10974362 1640144..1640353 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1640353 10974362 zobellia_1390 Zobellia galactanivorans hypothetical protein YP_004735834.1 1640144 D 63186 CDS YP_004735835.1 340617382 10974364 1640515..1640592 1 NC_015844.1 Hypothetical protein; hypothetical protein 1640592 10974364 zobellia_1391 Zobellia galactanivorans hypothetical protein YP_004735835.1 1640515 D 63186 CDS YP_004735836.1 340617383 10974365 1640592..1641110 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1641110 10974365 zobellia_1392 Zobellia galactanivorans hypothetical protein YP_004735836.1 1640592 D 63186 CDS YP_004735837.1 340617384 10974366 1641113..1641535 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the cytoplasmic and/or outer membrane; Hypothetical protein; hypothetical protein 1641535 10974366 zobellia_1393 Zobellia galactanivorans hypothetical protein YP_004735837.1 1641113 D 63186 CDS YP_004735838.1 340617385 10974367 1642497..1642721 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1642721 10974367 zobellia_1394 Zobellia galactanivorans hypothetical protein YP_004735838.1 1642497 D 63186 CDS YP_004735839.1 340617386 10974368 1642847..1643029 1 NC_015844.1 Hypothetical protein; hypothetical protein 1643029 10974368 zobellia_1395 Zobellia galactanivorans hypothetical protein YP_004735839.1 1642847 D 63186 CDS YP_004735840.1 340617387 10974369 1643126..1643368 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1643368 10974369 zobellia_1396 Zobellia galactanivorans hypothetical protein YP_004735840.1 1643126 D 63186 CDS YP_004735841.1 340617388 10974370 1643365..1643649 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 1643649 10974370 zobellia_1397 Zobellia galactanivorans hypothetical protein YP_004735841.1 1643365 D 63186 CDS YP_004735842.1 340617389 10974371 1643992..1646424 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1646424 10974371 zobellia_1398 Zobellia galactanivorans hypothetical protein YP_004735842.1 1643992 D 63186 CDS YP_004735843.1 340617390 10974372 1646475..1651856 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 1651856 10974372 zobellia_1399 Zobellia galactanivorans hypothetical protein YP_004735843.1 1646475 D 63186 CDS YP_004735844.1 340617391 10974373 1651838..1652146 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 1652146 10974373 zobellia_1400 Zobellia galactanivorans hypothetical protein YP_004735844.1 1651838 D 63186 CDS YP_004735845.1 340617392 10974376 1652468..1657480 1 NC_015844.1 Contains a signal peptide cleaved between the residues 25 and 26; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1657480 10974376 zobellia_1401 Zobellia galactanivorans periplasmic protein YP_004735845.1 1652468 D 63186 CDS YP_004735846.1 340617393 10974377 1657584..1659545 1 NC_015844.1 This conserved protein contains five type-III fibronectin (FN3) domains. Structures of individual FN3 domains have revealed a conserved beta sandwich fold with one beta sheet containing four strands and the other sheet containing three strands; Localized in the cytoplasm; Family membership; fibronectin type-III repeat-containing protein 1659545 10974377 zobellia_1402 Zobellia galactanivorans fibronectin type-III repeat-containing protein YP_004735846.1 1657584 D 63186 CDS YP_004735847.1 340617394 10974378 1659550..1664535 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1664535 10974378 zobellia_1403 Zobellia galactanivorans membrane protein YP_004735847.1 1659550 D 63186 CDS YP_004735848.1 340617395 10974379 complement(1664745..1665023) 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases are composed of two linked complexes: the F1 ATPase complex is the catalytic core, composed of 5 subunits (alpha, beta, gamma, delta, epsilon), and the F0 ATPase complex is the membrane-embedded proton channel, composed of at least 3 subunits (A-C). In the the F1 ATPase complex, the alpha and beta subunits form a cylinder that is attached to the central stalk composed of gamma, delta, epsilon subunits. The interaction site of subunit C of the F0 complex with the epsilon subunit of the F1 complex may be important for connecting the rotor of F1 (gamma subunit) to the rotor of F0 (C subunit).; High confidence in function and specificity; ATP synthase, F1 sector subunit epsilon 1665023 atpC1 10974379 atpC1 Zobellia galactanivorans ATP synthase, F1 sector subunit epsilon YP_004735848.1 1664745 R 63186 CDS YP_004735849.1 340617396 10977571 complement(1665093..1666601) 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases are composed of two linked complexes: the F1 ATPase complex is the catalytic core, composed of 5 subunits (alpha, beta, gamma, delta, epsilon), and the F0 ATPase complex is the membrane-embedded proton channel, composed of at least 3 subunits (A-C). In the the F1 ATPase complex, the alpha and beta subunits form a cylinder that is attached to the central stalk composed of gamma, delta, epsilon subunits. There are three copies each of the alpha and beta subunits where a substrate-binding site, on each of these subunits is present, those on the beta subunits being catalytic, while those on the alpha subunits are regulatory. The alpha/beta subunits undergo a sequence of conformational changes leading to the formation of ATP from ADP, which are induced by the rotation of the gamma subunit, itself is driven by the movement of protons through the F0 complex C subunit.; High confidence in function and specificity; ATP synthase, F1 sector subunit beta 1666601 atpD1 10977571 atpD1 Zobellia galactanivorans ATP synthase, F1 sector subunit beta YP_004735849.1 1665093 R 63186 CDS YP_004735850.1 340617397 10977573 complement(1666783..1668426) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1668426 10977573 zobellia_1406 Zobellia galactanivorans hypothetical protein YP_004735850.1 1666783 R 63186 CDS YP_004735851.1 340617398 10974380 complement(1668447..1671233) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations. Contains a Plug module (112-223) acting as a channel gate. The signal peptide is cleaved between the residues 24 and 25; Family membership; TonB-dependent Receptor 1671233 10974380 zobellia_1407 Zobellia galactanivorans TonB-dependent Receptor YP_004735851.1 1668447 R 63186 CDS YP_004735852.1 340617399 10974381 complement(1671433..1673280) 1 NC_015844.1 Glucosamine--fructose-6-phosphate aminotransferase catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. It forms a homodimer and is localized in the cytoplasm.; High confidence in function and specificity; glucosamine--fructose-6-phosphate aminotransferase 1673280 glmS 10974381 glmS Zobellia galactanivorans glucosamine--fructose-6-phosphate aminotransferase YP_004735852.1 1671433 R 63186 CDS YP_004735853.1 340617400 10977915 complement(1673468..1675303) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 23 and 24; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1675303 10977915 zobellia_1409 Zobellia galactanivorans lipoprotein YP_004735853.1 1673468 R 63186 CDS YP_004735854.1 340617401 10974382 complement(1675309..1676118) 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 5 of the glycosyltransferases. This protein of about 270 residues is conserved within the Bacteroidetes phylum and displays high similarity with the N-terminal region of glycogen synthase. Its exact specificity is unknown. Localized in the cytoplasm.; Specificity unclear; glycosyltransferase 1676118 10974382 zobellia_1410 Zobellia galactanivorans glycosyltransferase YP_004735854.1 1675309 R 63186 CDS YP_004735855.1 340617402 10974384 1676223..1677065 1 NC_015844.1 Pantoate-beta-alanine ligase, also know as pantothenate synthase, catalyzes the formation of pantothenate from pantoate and alanine in the pantothenate biosynthesis pathway. PanC is a homodimer and binds one ATP by subunit. Localized in the cytoplasm.; High confidence in function and specificity; Pantoate-beta-alanine ligase 1677065 panC 10974384 panC Zobellia galactanivorans Pantoate-beta-alanine ligase YP_004735855.1 1676223 D 63186 CDS YP_004735856.1 340617403 10978298 1677083..1677433 1 NC_015844.1 Aspartate 1-decarboxylase catalyzed the decarboxylation of aspartate, the major route of alanine production in bacteria. This enzyme is also involved in pantothenate biosynthesis. PanD requires a pyruvoyl group for its activity. It is synthesized initially as a proenzyme which is then proteolytically cleaved to an alpha (C-terminal) and beta (N-terminal) subunit and a pyruvoyl group. PanD forms a homotetramer and is localized in the cytoplasm.; High confidence in function and specificity; aspartate 1-decarboxylase 1677433 panD 10978298 panD Zobellia galactanivorans aspartate 1-decarboxylase YP_004735856.1 1677083 D 63186 CDS YP_004735857.1 340617404 10978299 1677436..1678401 1 NC_015844.1 Conserved integral membrane protein belonging to the UPF0104 family; Contains nine transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 1678401 10978299 zobellia_1413 Zobellia galactanivorans membrane protein YP_004735857.1 1677436 D 63186 CDS YP_004735858.1 340617405 10974385 1678429..1679571 1 NC_015844.1 Esterase adopting an alpha/beta hydrolase fold. Its exact specificity is unknown; Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Specificity unclear; esterase 1679571 10974385 zobellia_1414 Zobellia galactanivorans esterase YP_004735858.1 1678429 D 63186 CDS YP_004735859.1 340617406 10974386 1679641..1681002 1 NC_015844.1 May play a role in the repair of endogenous alkylation damage; Contains an N-terminal ATPase domain; Belongs to the recA family, RadA subfamily; Localized in the cytoplasm; High confidence in function and specificity; DNA repair protein 1681002 radA 10974386 radA Zobellia galactanivorans DNA repair protein YP_004735859.1 1679641 D 63186 CDS YP_004735860.1 340617407 10978430 complement(1681131..1682171) 1 NC_015844.1 Oxydoreductase NADPH dependent; Belongs to the aldo/keto reductase 2 family; Localized in the cytoplasm; Family membership; aldo/keto reductase 1682171 tasA 10978430 tasA Zobellia galactanivorans aldo/keto reductase YP_004735860.1 1681131 R 63186 CDS YP_004735861.1 340617408 10978638 complement(1682302..1683069) 1 NC_015844.1 The exonuclease III catalyses the cleavage in the 3'- to 5'-direction on double-stranded DNA to yield nucleoside 5'-phosphates. It also has an endonucleolytic activity near apurinic sites on DNA; Contains an Endonuclease/Exonuclease/phosphatase domains; Belongs to the DNA repair enzymes AP family 1; Localized in the cytoplasm; High confidence in function and specificity; exodeoxyribonuclease III 1683069 xthA2 10978638 xthA2 Zobellia galactanivorans exodeoxyribonuclease III YP_004735861.1 1682302 R 63186 CDS YP_004735862.1 340617409 10978763 complement(1683050..1683142) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1683142 10978763 zobellia_1418 Zobellia galactanivorans hypothetical protein YP_004735862.1 1683050 R 63186 CDS YP_004735863.1 340617410 10974387 1683156..1685237 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains the Plug module (43-152) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 1685237 10974387 zobellia_1419 Zobellia galactanivorans TonB-dependent Receptor YP_004735863.1 1683156 D 63186 CDS YP_004735864.1 340617411 10974388 complement(1685234..1686784) 1 NC_015844.1 Glycyl-tRNA synthetase catalyzes the attachment of glycine to its cognate transfer RNA molecule in a highly specific two-step reaction. Belongs to the class II aminoacyl-tRNA synthetase family. It forms a homodimer and is localized in the cytoplasm.; High confidence in function and specificity; glycyl-tRNA synthetase 1686784 glyQS 10974388 glyQS Zobellia galactanivorans glycyl-tRNA synthetase YP_004735864.1 1685234 R 63186 CDS YP_004735865.1 340617412 10977936 complement(1686822..1687718) 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1687718 10977936 zobellia_1421 Zobellia galactanivorans membrane protein YP_004735865.1 1686822 R 63186 CDS YP_004735866.1 340617413 10974390 1687776..1688483 1 NC_015844.1 Phosphoribosyltransferase carries out phosphoryl transfer reactions on 5-phosphoribosyl-alpha1-pyrophosphate, an activated form of ribose-5-phosphate. Its exact specificity is still unknown; Localized in the cytoplasm; Function unclear; phosphoribosyltransferase 1688483 10974390 zobellia_1422 Zobellia galactanivorans phosphoribosyltransferase YP_004735866.1 1687776 D 63186 CDS YP_004735867.1 340617414 10974391 1688522..1690132 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1690132 10974391 zobellia_1423 Zobellia galactanivorans lipoprotein YP_004735867.1 1688522 D 63186 CDS YP_004735868.1 340617415 10974392 complement(1690116..1690892) 1 NC_015844.1 This enzyme belongs to a family containing hydrolases that break carbon-nitrogen bonds and appear to be involved in the reduction of organic nitrogen compounds and ammonia production. It features the E-K-C catalytic triad conserved in Nitrilase-related proteins; Adopts a alpha-beta-beta-alpha sandwich fold; Localized in the cytoplasm; Family membership; carbon-nitrogen hydrolase 1690892 10974392 zobellia_1424 Zobellia galactanivorans carbon-nitrogen hydrolase YP_004735868.1 1690116 R 63186 CDS YP_004735869.1 340617416 10974393 complement(1690901..1691515) 1 NC_015844.1 ADP-ribose pyrophosphatase catalyzes the Mg2+-dependent hydrolysis of ADP-ribose to ribose-5-phosphate and AMP; Belongs to the NUDIX hydrolase family; Localized in the cytoplasm; High confidence in function and specificity; ADP-ribose pyrophosphatase 1691515 nudF 10974393 nudF Zobellia galactanivorans ADP-ribose pyrophosphatase YP_004735869.1 1690901 R 63186 CDS YP_004735870.1 340617417 10978279 complement(1691528..1692001) 1 NC_015844.1 Conserved protein containing three ankyrin repeats. The ankyrin repeat is involved in protein-protein interaction. Each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90o angle. The repeats stack together to form an L-shaped structure; Localized in the cytoplasm; Function unclear; ankyrin repeat-containing protein 1692001 10978279 zobellia_1426 Zobellia galactanivorans ankyrin repeat-containing protein YP_004735870.1 1691528 R 63186 CDS YP_004735871.1 340617418 10974394 complement(1692147..1693637) 1 NC_015844.1 This enzyme is a mono-functional haem-containing catalase that acts as an antioxidant enzyme catalyzing the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects. Localized in the cytoplasm.; High confidence in function and specificity; catalase 1693637 katA1 10974394 katA1 Zobellia galactanivorans catalase YP_004735871.1 1692147 R 63186 CDS YP_004735872.1 340617419 10978047 1693987..1696200 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains three N-terminal PAS/PAC domains involved in many signalling proteins where they are used as a signal sensor domain; Putatively localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 1696200 10978047 zobellia_1428 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004735872.1 1693987 D 63186 CDS YP_004735873.1 340617420 10974395 1696181..1696597 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity which acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership; two-component system-response regulator, receiver domain 1696597 10974395 zobellia_1429 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004735873.1 1696181 D 63186 CDS YP_004735874.1 340617421 10974396 1696655..1697050 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity which acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership; two-component system-response regulator, receiver domain 1697050 10974396 zobellia_1430 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004735874.1 1696655 D 63186 CDS YP_004735875.1 340617422 10974398 complement(1697057..1698436) 1 NC_015844.1 Lipoprotein that contains a C-terminal domain of 150 residues Signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Hypothetical protein; hypothetical protein 1698436 10974398 zobellia_1431 Zobellia galactanivorans hypothetical protein YP_004735875.1 1697057 R 63186 CDS YP_004735876.1 340617423 10974399 complement(1698447..1701176) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (23-97) and the Plug module (107-214) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 1701176 10974399 zobellia_1432 Zobellia galactanivorans TonB-dependent Receptor YP_004735876.1 1698447 R 63186 CDS YP_004735877.1 340617424 10974400 1701298..1702344 1 NC_015844.1 The Endonuclease/exonuclease/phosphatase domain is found in a large number of proteins including magnesium dependent endonucleases and phosphatases involved in intracellular signalling; Belongs to the Endonuclease/Exonuclease/phosphatase family; Signal peptide cleaved between the residues 18 and 19; Probably localized in the periplasmic space; Family membership; endonuclease/exonuclease/phosphatase family protein 1702344 10974400 zobellia_1433 Zobellia galactanivorans endonuclease/exonuclease/phosphatase family protein YP_004735877.1 1701298 D 63186 CDS YP_004735878.1 340617425 10974401 complement(1702401..1703531) 1 NC_015844.1 Protein that contains nine MORN repeat variants including five repeats of twenty aminoacids; The MORN (membrane occupation and recognition nexus) repeats would contribute to the plasma membrane binding, possibly by interacting with phospholipids; Signal peptide cleaved between the residues 27 and 28; Probably localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1703531 10974401 zobellia_1434 Zobellia galactanivorans periplasmic protein YP_004735878.1 1702401 R 63186 CDS YP_004735879.1 340617426 10974402 complement(1703849..1704499) 1 NC_015844.1 Conserved protein belonging to the DUF1080 family; Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasm; Conserved hypothetical protein; periplasmic protein 1704499 10974402 zobellia_1435 Zobellia galactanivorans periplasmic protein YP_004735879.1 1703849 R 63186 CDS YP_004735880.1 340617427 10974403 complement(1704487..1704927) 1 NC_015844.1 Contains four transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1704927 10974403 zobellia_1436 Zobellia galactanivorans membrane protein YP_004735880.1 1704487 R 63186 CDS YP_004735881.1 340617428 10974404 complement(1705019..1707574) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-97) and the Plug module (116-226) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 1707574 10974404 zobellia_1437 Zobellia galactanivorans TonB-dependent Receptor YP_004735881.1 1705019 R 63186 CDS YP_004735882.1 340617429 10974405 complement(1707746..1709383) 1 NC_015844.1 Glucose-6-phosphate isomerase is a dimeric enzyme that catalyses the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate in the second step of glycolysis (Embden-Meyerhof pathway) and in oxydative phase of pentose phosphate pathway. PgiA also is involved in the gluconeogenesis and in Pentose phosphate pathway; Localized in the cytoplasm; High confidence in function and specificity; glucose-6-phosphate isomerase 1709383 pgiA 10974405 pgiA Zobellia galactanivorans glucose-6-phosphate isomerase YP_004735882.1 1707746 R 63186 CDS YP_004735883.1 340617430 10978336 complement(1709463..1710758) 1 NC_015844.1 Endopeptidases that probably lyzes the bacterial cell wall peptidoglycan. One catalytic zinc ion is bound per peptidase molecule; Belongs to the M23 family of peptidases; Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly loclaized in the outer membrane; Specificity unclear; metallopeptidase 1710758 10978336 zobellia_1439 Zobellia galactanivorans metallopeptidase YP_004735883.1 1709463 R 63186 CDS YP_004735884.1 340617431 10974406 complement(1710760..1711731) 1 NC_015844.1 Tryptophan 2,3-dioxygenase is Involved in L-kynurenine metabolism from L-tryptophan,incorporating oxygen into the indole moiety of tryptophan. It has a broad specificity towards tryptamine and derivatives including D-and L-tryptophan, 5-hydroxytryptophan and serotonin; This enzyme forms a tetramer and binds 2 hemes per subunit; Localized in the cytoplasm; High confidence in function and specificity; tryptophan 2,3-dioxygenase 1711731 tdoA2 10974406 tdoA2 Zobellia galactanivorans tryptophan 2,3-dioxygenase YP_004735884.1 1710760 R 63186 CDS YP_004735885.1 340617432 10978645 complement(1711737..1712516) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic; Conserved hypothetical protein; periplasmic protein 1712516 10978645 zobellia_1441 Zobellia galactanivorans periplasmic protein YP_004735885.1 1711737 R 63186 CDS YP_004735886.1 340617433 10974408 complement(1713004..1714146) 1 NC_015844.1 4-hydroxyphenylpyruvate dioxygenase is involved in L_phenylalanine degradation. It oxidizes 4-hydroxyphenylpyruvate, a tyrosine and phenylalanine catabolite, to homogentisate. Homogentisate can undergo a further non-enzymatic oxidation and polymerization into brown pigments that protect some bacterial species from light. HpdA forms a homodimer and binds one iron ion by subunit. Localized in the cytoplasm.; High confidence in function and specificity; 4-hydroxyphenylpyruvate dioxygenase 1714146 hpdA 10974408 hpdA Zobellia galactanivorans 4-hydroxyphenylpyruvate dioxygenase YP_004735886.1 1713004 R 63186 CDS YP_004735887.1 340617434 10977991 complement(1714334..1716625) 1 NC_015844.1 Conserved protein containing a N-terminal Patatin-like phospholipase domain and a C-terminal domain of unknown function; Contains a signal peptide cleaved between the residues 32 and 33; Localized in the periplasmic space; Family membership; Patatin-like phospholipase 1716625 10977991 zobellia_1443 Zobellia galactanivorans Patatin-like phospholipase YP_004735887.1 1714334 R 63186 CDS YP_004735888.1 340617435 10974409 complement(1716609..1718396) 1 NC_015844.1 The UvrC protein belongs to the UvrABC repair system responsible of the recognition and processing of DNA lesions. UvrC catalyses the first incision on the fourth or fifth phosphodiester bond 3' and on the eighth phosphodiester bond 5' from the damage that is to be excised; The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; Contains a C-terminal non-sequence-specific DNA binding HhH domain; Localized in the cytoplasm; High confidence in function and specificity; excinuclease ABC subunit C 1718396 uvrC 10974409 uvrC Zobellia galactanivorans excinuclease ABC subunit C YP_004735888.1 1716609 R 63186 CDS YP_004735889.1 340617436 10978734 1718839..1719402 1 NC_015844.1 Methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclodehydrase) catalyzes the ATP-and Mg2+-dependent transformation of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate. Localized in the cytoplasm.; High confidence in function and specificity; 5-formyltetrahydrofolate cyclo-ligase 1719402 MthfS 10978734 MthfS Zobellia galactanivorans 5-formyltetrahydrofolate cyclo-ligase YP_004735889.1 1718839 D 63186 CDS YP_004735890.1 340617437 10978197 complement(1719406..1720047) 1 NC_015844.1 The signal peptidase II specifically catalyzes the removal of signal peptides from prolipoproteins. Belongs to the family 8 of the aspartic peptidases. Two aspartate residues are essential for activity. They occur in the motifs GNXXDRX and FNXAD where X is a hydrophobic residue. Cleavage of the prelipoprotein occurs on the amino side of a modified cysteine residue, the thiol group of which is substituted with a diacylglyceryl group (an activity of phosphatidylglycerol:prolipoprotein diacylglyceryl transferase). The consensus around the cleavage site is known as the \\lipobox sequence\\ and is Leu-Xaa-YaaCys in which Xaa is Ala or Ser and Yaa is Gly or Ala. LpsA is membrane bound with four transmembrane domains.; High confidence in function and specificity; signal peptidase II, family A8 1720047 lspA 10978197 lspA Zobellia galactanivorans signal peptidase II, family A8 YP_004735890.1 1719406 R 63186 CDS YP_004735891.1 340617438 10978108 complement(1720085..1720765) 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1720765 10978108 zobellia_1447 Zobellia galactanivorans membrane protein YP_004735891.1 1720085 R 63186 CDS YP_004735892.1 340617439 10974410 complement(1720770..1721153) 1 NC_015844.1 Protein that belongs to the DksA family, which includes the DnaK suppressor protein (DksA); Contains a 4-cysteine zinc finger in the C-terminal region; Localized in the cytoplasm; Family membership; Zinc-finger protein 1721153 10974410 zobellia_1448 Zobellia galactanivorans Zinc-finger protein YP_004735892.1 1720770 R 63186 CDS YP_004735893.1 340617440 10974411 complement(1721158..1724556) 1 NC_015844.1 Isoleucyl-tRNA synthetase catalyzes the attachment of isoleucine to tRNA(Ile). As IleS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). IleS has two distinct active sites: one for aminoacylation and one for editing. It binds one zinc ion as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; isoleucyl-tRNA synthetase 1724556 ileS 10974411 ileS Zobellia galactanivorans isoleucyl-tRNA synthetase YP_004735893.1 1721158 R 63186 CDS YP_004735894.1 340617441 10978028 1724748..1725155 1 NC_015844.1 Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1725155 10978028 zobellia_1450 Zobellia galactanivorans periplasmic protein YP_004735894.1 1724748 D 63186 CDS YP_004735895.1 340617442 10974413 complement(1725232..1727643) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-96) and the Plug module (111-219) acting as a channel gate; The signal peptide is cleaved between the residues 18 and 19; Family membership; TonB-dependent Receptor 1727643 10974413 zobellia_1451 Zobellia galactanivorans TonB-dependent Receptor YP_004735895.1 1725232 R 63186 CDS YP_004735896.1 340617443 10974414 complement(1727645..1728364) 1 NC_015844.1 RecO may play a role in DNA repair. It seems to be involved in an recBC-independent recombinational process of DNA repair. It may act with recF and recR; RecO may adopt a mononucleotide-binding fold; Localized in the cytoplasm; High confidence in function and specificity; DNA repair protein RecO 1728364 recO 10974414 recO Zobellia galactanivorans DNA repair protein RecO YP_004735896.1 1727645 R 63186 CDS YP_004735897.1 340617444 10978446 complement(1728493..1729836) 1 NC_015844.1 Glutamate dehydrogenase catalyzes the NAD- and/or NADP-dependent reversible deamination of L-glutamate into alpha-ketoglutarate. It is involved with either ammonia assimilation or glutamate catabolism. Forms a homohexamer and binds one NAD(P) cofactor by subunit. Localized in the cytoplasm.; High confidence in function and specificity; glutamate dehydrogenase 1729836 gdhA1 10978446 gdhA1 Zobellia galactanivorans glutamate dehydrogenase YP_004735897.1 1728493 R 63186 CDS YP_004735898.1 340617445 10977887 complement(1729944..1731098) 1 NC_015844.1 The Cystathionine gamma-synthase is found in the Selenoamino acid metabolism pathway and involved in the second step of the methionine biosynthesis; Uses a pyridoxal phosphate group as cofactor, attached to a lysine residue located in the central section of the enzyme; Localized in the cytoplasm; High confidence in function and specificity; cystathionine gamma-synthase 1731098 metB 10977887 metB Zobellia galactanivorans cystathionine gamma-synthase YP_004735898.1 1729944 R 63186 CDS YP_004735899.1 340617446 10978147 1731186..1731926 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1731926 10978147 zobellia_1455 Zobellia galactanivorans hypothetical protein YP_004735899.1 1731186 D 63186 CDS YP_004735900.1 340617447 10974415 complement(1731930..1732391) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1732391 10974415 zobellia_1456 Zobellia galactanivorans hypothetical protein YP_004735900.1 1731930 R 63186 CDS YP_004735901.1 340617448 10974416 1732467..1732832 1 NC_015844.1 Conserved protein belonging to the Arsenate reductase (ArsC) family; Localized in the cytoplasm; Family membership; ArsC family protein 1732832 10974416 zobellia_1457 Zobellia galactanivorans ArsC family protein YP_004735901.1 1732467 D 63186 CDS YP_004735902.1 340617449 10974417 1732829..1733731 1 NC_015844.1 Integral membrane protein belonging to the DUF6 family; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 1733731 10974417 zobellia_1458 Zobellia galactanivorans membrane protein YP_004735902.1 1732829 D 63186 CDS YP_004735903.1 340617450 10974418 complement(1733706..1734182) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1734182 10974418 zobellia_1459 Zobellia galactanivorans hypothetical protein YP_004735903.1 1733706 R 63186 CDS YP_004735904.1 340617451 10974419 1734305..1735279 1 NC_015844.1 2-Nitropropane dioxygenase catalyzes the oxidation of nitroalkanes to produce the corresponding carbonyl compounds. It acts on 2-nitropropane better than on nitroethane and 1-nitropropane, and anionic forms of nitroalkanes are much better substrates than are neutral forms. It forms a homodimer and uses FMN as cofactor; Localized in the cytoplasm; High confidence in function and specificity; 2-nitropropane dioxygenase 1735279 ncd2 10974419 ncd2 Zobellia galactanivorans 2-nitropropane dioxygenase YP_004735904.1 1734305 D 63186 CDS YP_004735905.1 340617452 10978241 complement(1735335..1737008) 1 NC_015844.1 This protein consists of an N-terminal cyclic nucleotide binding domain and a C-terminal thioreductase domain; This Enzyme is a pyridine nucleotide-disulphide reductases (PNDR) where the active site is a redox-active disulfide bond. Acts as an homodimer, binds one FAD molecule per subunit and is regulated by the cyclic nucleotide binding (cAMP or cGMP); Localized in the cytoplasm; High confidence in function and specificity; cyclic nucleotide dependent thioredoxin reductase 1737008 10978241 zobellia_1461 Zobellia galactanivorans cyclic nucleotide dependent thioredoxin reductase YP_004735905.1 1735335 R 63186 CDS YP_004735906.1 340617453 10974421 1737354..1738316 1 NC_015844.1 The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Localized in the cytoplasm; Function unclear; alpha/beta hydrolase-fold protein 1738316 10974421 zobellia_1462 Zobellia galactanivorans alpha/beta hydrolase-fold protein YP_004735906.1 1737354 D 63186 CDS YP_004735907.1 340617454 10974422 1738392..1738877 1 NC_015844.1 Cytochromes c typically function in electron transfer. They are required during oxidative phosphorylation as an electron shuttle between Complex III (cytochrome c reductase) and IV (cytochrome c oxidase), but c-type cytochrome centers are also found in the active sites of many enzymes; Cytochrome c binds a heme as prosthetic group by Cys85 and Cys88. His89 is involved in iron binding; Belongs to class I (mono-heme) of Cytochrome c; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Probably localized in the cytoplasmic and/or outer membrane; Function unclear; cytochrome c 1738877 10974422 zobellia_1463 Zobellia galactanivorans cytochrome c YP_004735907.1 1738392 D 63186 CDS YP_004735908.1 340617455 10974423 1738941..1740101 1 NC_015844.1 This protein belongs to the family 105 of the glycoside hydrolases. These enzymes are involved in the catabolism of unsaturated oligosaccharides produced by polysaccharide lyases. Asp175 is the putative catalytic residue (identical to Asp143 of the unsaturated rhamnogalacturonyl hydrolase from Bacillus subtilis, Itoh et al., 2006, BBRC 347, 10211029). Features an uncleaved signal peptide. Localized in the cytoplasmic membrane.; Specificity unclear; glycoside hydrolase 1740101 10974423 zobellia_1464 Zobellia galactanivorans glycoside hydrolase YP_004735908.1 1738941 D 63186 CDS YP_004735909.1 340617456 10974424 complement(1740140..1741729) 1 NC_015844.1 Protein belonging to the sulfate transporter family. It may play a role in the regulation of sulfate assimilation; Contains a C-terminal STAS domain (Sulphate Transporter and AntiSigma factor antagonist), which has been suggested to have a general NTP binding function; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sulfate transporter 1741729 10974424 zobellia_1465 Zobellia galactanivorans sulfate transporter YP_004735909.1 1740140 R 63186 CDS YP_004735910.1 340617457 10974425 complement(1741979..1742890) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the cytoplasmic and/or outer membrane; Conserved hypothetical protein; lipoprotein 1742890 10974425 zobellia_1466 Zobellia galactanivorans lipoprotein YP_004735910.1 1741979 R 63186 CDS YP_004735911.1 340617458 10974426 1743065..1744060 1 NC_015844.1 NAD(P)-dependent glycerol-3-phosphate dehydrogenase is involved in phospholipid biosynthesis. It converts the sn-glycerol 3-phosphate to glycerone phosphate. It forms a homodimer, each monomer containing an N-terminal NAD binding domain and a C-terminal substrate-binding domain; Localized in the cytoplasm; High confidence in function and specificity; glycerol-3-phosphate dehydrogenase [NAD(P)+] 1744060 gpsA 10974426 gpsA Zobellia galactanivorans glycerol-3-phosphate dehydrogenase [NAD(P)+] YP_004735911.1 1743065 D 63186 CDS YP_004735912.1 340617459 10977949 complement(1744154..1745821) 1 NC_015844.1 Glycerol-3-phosphate dehydrogenase is involved in glycerol catabolism. It converts the sn-glycerol 3-phosphate to glycerone phosphate; Uses FAD as cofactor; Localized in the cytoplasm; High confidence in function and specificity; glycerol-3-phosphate dehydrogenase 1745821 glpD 10977949 glpD Zobellia galactanivorans glycerol-3-phosphate dehydrogenase YP_004735912.1 1744154 R 63186 CDS YP_004735913.1 340617460 10977920 complement(1745868..1747349) 1 NC_015844.1 Glycerol kinase is a key enzyme in the regulation of glycerol uptake and metabolism. It converts the glycerol to sn-glycerol 3-phosphate. It forms either a homotetramer or a homodimer (in equilibrium). Activity of this regulatory enzyme is affected by several metabolites; Localized in the cytoplasm; High confidence in function and specificity; glycerol kinase 1747349 glpK 10977920 glpK Zobellia galactanivorans glycerol kinase YP_004735913.1 1745868 R 63186 CDS YP_004735914.1 340617461 10977926 complement(1747452..1749797) 1 NC_015844.1 Penicillin-binding protein 1C is a class A PBP involved in the synthesis of cross-linked peptidoglycan from the lipid II intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase central domain which may not be functional and a C-terminal domain of unknown function which is conserved in this sub-family of PBPs. The N-terminal domain belongs to the family 51 of the glycosyltransferases. Features an uncleaved signal peptide. Localized in the periplasm, anchored to the cytoplasmic membrane.; High confidence in function and specificity; penicillin-binding protein 1C, family GT51 1749797 pbp1C 10977926 pbp1C Zobellia galactanivorans penicillin-binding protein 1C, family GT51 YP_004735914.1 1747452 R 63186 CDS YP_004735915.1 340617462 10978307 complement(1749912..1750268) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1750268 10978307 zobellia_1471 Zobellia galactanivorans hypothetical protein YP_004735915.1 1749912 R 63186 CDS YP_004735916.1 340617463 10974428 1750351..1750887 1 NC_015844.1 Conserved membrane protein distantly related to Colicin V production protein; Contains three transmembrane helices; Localized in the cytoplasmic membrane; Family membership; cvpA family protein 1750887 10974428 zobellia_1472 Zobellia galactanivorans cvpA family protein YP_004735916.1 1750351 D 63186 CDS YP_004735917.1 340617464 10974429 1750938..1751984 1 NC_015844.1 Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1751984 10974429 zobellia_1473 Zobellia galactanivorans membrane protein YP_004735917.1 1750938 D 63186 CDS YP_004735918.1 340617465 10974430 1752207..1752626 1 NC_015844.1 Contains a putattive lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Hypothetical protein; hypothetical protein 1752626 10974430 zobellia_1474 Zobellia galactanivorans hypothetical protein YP_004735918.1 1752207 D 63186 CDS YP_004735919.1 340617466 10974431 complement(1752705..1758218) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1758218 10974431 zobellia_1475 Zobellia galactanivorans lipoprotein YP_004735919.1 1752705 R 63186 CDS YP_004735920.1 340617467 10974432 1758563..1759039 1 NC_015844.1 SCP-like extracellular proteins have been proposed to be a calcium ion chelating serine proteases. The Calcium-chelating function would fit with the various signalling processes where members of this family are involved, and also the structural evidences of a conserved pocket containing two histidines and a glutamate; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Family membership; SCP-like extracellular protein 1759039 10974432 zobellia_1476 Zobellia galactanivorans SCP-like extracellular protein YP_004735920.1 1758563 D 63186 CDS YP_004735921.1 340617468 10974433 1759182..1759721 1 NC_015844.1 3-Hydroxyanthranilate 3,4-dioxygenase is involved in the 2-nitrobenzoate degradation pathway. It catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. It forms a homodimer and binds 2 Fe(2+) ions per subunit. Localized in the cytoplasm.; High confidence in function and specificity; 3-hydroxyanthranilate 3,4-dioxygenase 1759721 nbaC 10974433 nbaC Zobellia galactanivorans 3-hydroxyanthranilate 3,4-dioxygenase YP_004735921.1 1759182 D 63186 CDS YP_004735922.1 340617469 10978239 1759814..1761427 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain. Contains an uncleaved signal peptide and a N-terminal CHASE (Cyclases/Histidine kinases Associated Sensory Extracellular) domain. The CHASE domain is predicted to bind diverse low molecular weight ligands and mediate signal transduction through the respective receptors. It has a predicted alpha+beta fold, with two extended alpha helices on both boundaries and two central alpha helices separated by beta sheets. This protein is localized in the cytoplasmic membrane.; Specificity unclear; two-component system-sensor histidine kinase 1761427 10978239 zobellia_1478 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004735922.1 1759814 D 63186 CDS YP_004735923.1 340617470 10974434 1761443..1761796 1 NC_015844.1 Conserved protein belonging to the DUF1304 family; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 1761796 10974434 zobellia_1479 Zobellia galactanivorans membrane protein YP_004735923.1 1761443 D 63186 CDS YP_004735924.1 340617471 10974435 1761931..1763484 1 NC_015844.1 Piperideine-6-carboxylate dehydrogenase catalyses the conversion of Delta-1-Piperideine-6-carboxylate into alpha-aminoadipic acid. This latter compound is a precursor of cephamycin C antibiotic; Localized in the cytoplasm; High confidence in function and specificity; piperideine-6-carboxylate dehydrogenase 1763484 pcdA 10974435 pcdA Zobellia galactanivorans piperideine-6-carboxylate dehydrogenase YP_004735924.1 1761931 D 63186 CDS YP_004735925.1 340617472 10978311 complement(1763615..1763929) 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 1763929 10978311 zobellia_1481 Zobellia galactanivorans hypothetical protein YP_004735925.1 1763615 R 63186 CDS YP_004735926.1 340617473 10974437 1764100..1765017 1 NC_015844.1 Protein that contains a C-terminal OmpA-like domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Contains a uncleavable signal peptide; Localized in the cytoplasmic membrane; Function unclear; OmpA-like membrane protein 1765017 10974437 zobellia_1482 Zobellia galactanivorans OmpA-like membrane protein YP_004735926.1 1764100 D 63186 CDS YP_004735927.1 340617474 10974438 1765041..1765604 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1765604 10974438 zobellia_1483 Zobellia galactanivorans membrane protein YP_004735927.1 1765041 D 63186 CDS YP_004735928.1 340617475 10974439 complement(1765619..1765747) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1765747 10974439 zobellia_1484 Zobellia galactanivorans hypothetical protein YP_004735928.1 1765619 R 63186 CDS YP_004735929.1 340617476 10974440 complement(1765963..1766961) 1 NC_015844.1 Acyl-[acyl-carrier-protein] desaturase (or Stearoyl-ACP desaturase) converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons Delta(9) and Delta(10) of the acyl chain. It forms a homodimer. Involved in lipid metabolism. localized in the cytoplasm.; High confidence in function and specificity; acyl-ACP desaturase 1766961 ACPD 10974440 ACPD Zobellia galactanivorans acyl-ACP desaturase YP_004735929.1 1765963 R 63186 CDS YP_004735930.1 340617477 10977463 complement(1767027..1767752) 1 NC_015844.1 Serine/threonine-protein phosphatase catalyzes the reaction: a phosphoprotein + H2O = a protein + phosphate. It binds one iron ion and one manganese ion. Belongs to the metallo-phosphoesterase family. Localized in the cytoplasm.; High confidence in function and specificity; serine/threonine-protein phosphatase 1767752 10977463 zobellia_1486 Zobellia galactanivorans serine/threonine-protein phosphatase YP_004735930.1 1767027 R 63186 CDS YP_004735931.1 340617478 10974441 complement(1767749..1768831) 1 NC_015844.1 Contains a C-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1768831 10974441 zobellia_1487 Zobellia galactanivorans membrane protein YP_004735931.1 1767749 R 63186 CDS YP_004735932.1 340617479 10974442 complement(1768888..1770024) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1770024 10974442 zobellia_1488 Zobellia galactanivorans hypothetical protein YP_004735932.1 1768888 R 63186 CDS YP_004735933.1 340617480 10974443 1770357..1773542 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (39-113) and the Plug module (129-236) acting as a channel gate; The signal peptide is cleaved between the residues 27 and 28; Family membership; TonB-dependent Receptor 1773542 10974443 zobellia_1489 Zobellia galactanivorans TonB-dependent Receptor YP_004735933.1 1770357 D 63186 CDS YP_004735934.1 340617481 10974444 1773562..1775364 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 23 and 24; Probably localized in the cytoplasmic membrane; Family membership; SusD/RagB family lipoprotein 1775364 10974444 zobellia_1490 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004735934.1 1773562 D 63186 CDS YP_004735935.1 340617482 10974446 1775549..1776496 1 NC_015844.1 Fructokinase catalyzes the transfert of phosphate group from ATP to convert the fructose to fructose-6-phosphate, which is an entry point into glycolysis (Embden-Meyerhof pathway) via conversion into glucose-6-phosphate; Belongs to the carbohydrate kinase pfkB superfamily, bacterial fructokinase family; Localized in the cytoplasm; High confidence in function and specificity; fructokinase 1776496 scrK1 10974446 scrK1 Zobellia galactanivorans fructokinase YP_004735935.1 1775549 D 63186 CDS YP_004735936.1 340617483 10978567 complement(1776501..1777637) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1777637 10978567 zobellia_1492 Zobellia galactanivorans hypothetical protein YP_004735936.1 1776501 R 63186 CDS YP_004735937.1 340617484 10974447 complement(1777634..1778389) 1 NC_015844.1 Catalyzes the NADP-dependent oxidation of L-allo-threonine and L-serine; Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity; NADP-dependent L-serine/L-allo-threonine dehydrogenase 1778389 10974447 zobellia_1493 Zobellia galactanivorans NADP-dependent L-serine/L-allo-threonine dehydrogenase YP_004735937.1 1777634 R 63186 CDS YP_004735938.1 340617485 10974448 complement(1778408..1779283) 1 NC_015844.1 Oxydoreductase NADPH dependent; Belongs to the aldo/keto reductase 2 family; Localized in the cytoplasm; Family membership; aldo/keto reductase 1779283 10974448 zobellia_1494 Zobellia galactanivorans aldo/keto reductase YP_004735938.1 1778408 R 63186 CDS YP_004735939.1 340617486 10974449 1779442..1780443 1 NC_015844.1 MoxR-like ATPases have been proposed to function with VWA domain proteins to form a chaperone system involved in the activation of proteins by primarily mediating the insertion of metal cofactors into the substrate molecules; Belongs to the MoxR-like family; Localized in the cytoplasm; Function unclear; MoxR-like ATPase 1780443 10974449 zobellia_1495 Zobellia galactanivorans MoxR-like ATPase YP_004735939.1 1779442 D 63186 CDS YP_004735940.1 340617487 10974450 1780532..1781398 1 NC_015844.1 Conserved protein belonging to the von Willebrand factor type A (vWA) domain family. Some VWA domain proteins have been proposed to function with MoxR-like ATPases to form a chaperone system involved in the activation of proteins by primarily mediating the insertion of metal cofactors into the substrate molecules; Localized in the cytoplasm; Family membership; vWA domain-containing protein 1781398 10974450 zobellia_1496 Zobellia galactanivorans vWA domain-containing protein YP_004735940.1 1780532 D 63186 CDS YP_004735941.1 340617488 10974451 1781398..1783062 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1783062 10974451 zobellia_1497 Zobellia galactanivorans membrane protein YP_004735941.1 1781398 D 63186 CDS YP_004735942.1 340617489 10974452 1783063..1784061 1 NC_015844.1 The protein BatA is a membrane protein belonging to the Bat operon (Bacteroides aerotolerance). Its exact function is unknown. Contains two N-terminal a transmembrane helices, three von Willebrand factor type A domain and a C-terminal transmembrane helix; Localized in the cytoplasmic membrane; Function unclear; Aerotolerance protein BatA 1784061 batA 10974452 batA Zobellia galactanivorans Aerotolerance protein BatA YP_004735942.1 1783063 D 63186 CDS YP_004735943.1 340617490 10977584 1784122..1785171 1 NC_015844.1 The protein BatB is a membrane protein belonging to the Bat operon (Bacteroides aerotolerance). Its exact function is unknown; Contains two N-terminal a transmembrane helices, three von Willebrand factor type A domain and a C-terminal transmembrane helix; Localized in the cytoplasmic membrane; Function unclear; aerotolerance protein BatB 1785171 batB 10977584 batB Zobellia galactanivorans aerotolerance protein BatB YP_004735943.1 1784122 D 63186 CDS YP_004735944.1 340617491 10977585 1785172..1786029 1 NC_015844.1 The protein BatC is a conserved protein belonging to the Bat operon (Bacteroides aerotolerance). Its exact function is unknown. Contains three N-terminal Tetratricopeptide repeats; Signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Function unclear; aerotolerance protein BatC 1786029 batC 10977585 batC Zobellia galactanivorans aerotolerance protein BatC YP_004735944.1 1785172 D 63186 CDS YP_004735945.1 340617492 10977586 1786068..1787807 1 NC_015844.1 The protein BatD is a membrane protein belonging to the Bat operon (Bacteroides aerotolerance). Its exact function is unknown. Contains a C-terminal transmembrane helices; Localized in the cytoplasmic membrane; Function unclear; aerotolerance protein BatD 1787807 batD 10977586 batD Zobellia galactanivorans aerotolerance protein BatD YP_004735945.1 1786068 D 63186 CDS YP_004735946.1 340617493 10977587 1787812..1788570 1 NC_015844.1 The protein BatE is a membrane protein belonging to the Bat operon (Bacteroides aerotolerance). Its exact function is unknown; Contains two N-terminal Tetratricopeptide repeats, two central transmembrane helices and a C-terminal bacterial SH3 domain; Localized in the cytoplasmic membrane.; Function unclear; aerotolerance protein BatE 1788570 batE 10977587 batE Zobellia galactanivorans aerotolerance protein BatE YP_004735946.1 1787812 D 63186 CDS YP_004735947.1 340617494 10977588 1788630..1788926 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1788926 10977588 zobellia_1503 Zobellia galactanivorans membrane protein YP_004735947.1 1788630 D 63186 CDS YP_004735948.1 340617495 10974454 1788996..1789367 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1789367 10974454 zobellia_1504 Zobellia galactanivorans hypothetical protein YP_004735948.1 1788996 D 63186 CDS YP_004735949.1 340617496 10974455 1789644..1790240 1 NC_015844.1 Carbonate dehydratase (or carbonic anhydrases) is a zinc metalloenzyme which catalyzes the reversible hydration of carbon dioxide. This enzyme is usually involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase. By this action, it prevents the depletion of cellular bicarbonate. Homodimer that binds one zinc ion by subunit; Belongs to the beta class of carbonic anhydrases; Localized in the cytoplasm.; High confidence in function and specificity; carbonate dehydratase 1790240 canA1 10974455 canA1 Zobellia galactanivorans carbonate dehydratase YP_004735949.1 1789644 D 63186 CDS YP_004735950.1 340617497 10977615 1790344..1790970 1 NC_015844.1 Carbonate dehydratase (or carbonic anhydrases) is a zinc metalloenzyme which catalyzes the reversible hydration of carbon dioxide. This enzyme is usually involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase. By this action, it prevents the depletion of cellular bicarbonate. Homodimer that binds one zinc ion by subunit; Belongs to the beta class of carbonic anhydrases; Localized in the cytoplasm.; High confidence in function and specificity; carbonate dehydratase 1790970 canA2 10977615 canA2 Zobellia galactanivorans carbonate dehydratase YP_004735950.1 1790344 D 63186 CDS YP_004735951.1 340617498 10977616 1791062..1792942 1 NC_015844.1 Protein belonging to the sulfate transporter family. Contains a C-terminal STAS domain (Sulphate Transporter and AntiSigma factor antagonist), which has been suggested to have have a general NTP binding function; Contains twelve transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sulfate transporter 1792942 10977616 zobellia_1507 Zobellia galactanivorans sulfate transporter YP_004735951.1 1791062 D 63186 CDS YP_004735952.1 340617499 10974456 1793021..1794040 1 NC_015844.1 PheS encodes the alpha subunit of Phenylalanyl-tRNA synthetase. the Phenylalanyl-tRNA synthetase is an alpha2/beta2 tetramer that catalyzes the attachment of phenylalanine to its cognate transfer RNA molecule in a highly specific two-step reaction; Binds 2 magnesium ions per tetramer; Belongs to class II aminoacyl-tRNA synthetases; Localized in the cytoplasm; High confidence in function and specificity; phenylalanyl-tRNA synthetase subunit alpha 1794040 pheS 10974456 pheS Zobellia galactanivorans phenylalanyl-tRNA synthetase subunit alpha YP_004735952.1 1793021 D 63186 CDS YP_004735953.1 340617500 10978341 1794051..1794446 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1794446 10978341 zobellia_1509 Zobellia galactanivorans hypothetical protein YP_004735953.1 1794051 D 63186 CDS YP_004735954.1 340617501 10974457 1794552..1795034 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1795034 10974457 zobellia_1510 Zobellia galactanivorans hypothetical protein YP_004735954.1 1794552 D 63186 CDS YP_004735955.1 340617502 10974458 1795117..1796202 1 NC_015844.1 These membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics, solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmique membrane by a N-terminal transmembrane region; Family membership; membrane fusion protein 1796202 10974458 zobellia_1511 Zobellia galactanivorans membrane fusion protein YP_004735955.1 1795117 D 63186 CDS YP_004735956.1 340617503 10974459 1796240..1799386 1 NC_015844.1 Integral membrane protein involved in drug resistance that belongs to the acrB/acrD/acrF family; Contains 12 transmembrane segments and two large periplasmic domains (each exceeding 300 residues) between helices 1 and 2, and helices 7 and 8. The three transmembrane domains form a large, 30-wide central cavity that spans the cytoplasmic membrane and extends to the cytoplasm; Localized in the cytoplasmic membrane; Family membership; multidrug efflux transporter 1799386 10974459 zobellia_1512 Zobellia galactanivorans multidrug efflux transporter YP_004735956.1 1796240 D 63186 CDS YP_004735957.1 340617504 10974460 1799394..1800797 1 NC_015844.1 The outer membrane efflux proteins (OEP) are composed of two repeats of OEP domain to form a trimeric channel continuous, solvent-accessible conduit that spans both the outer membrane and periplasmic space; May be specialized for the signal peptide independent extracellular secretion of a variety of substrates in Gram-negative bacteria (type I secretion system); Signal peptide of lipoprotein cleaved between the residues 21 and 22; Localized in the outer membrane; Family membership; outer membrane efflux protein 1800797 10974460 zobellia_1513 Zobellia galactanivorans outer membrane efflux protein YP_004735957.1 1799394 D 63186 CDS YP_004735958.1 340617505 10974461 1800811..1801419 1 NC_015844.1 Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership; TetR family transcriptional regulator 1801419 10974461 zobellia_1514 Zobellia galactanivorans TetR family transcriptional regulator YP_004735958.1 1800811 D 63186 CDS YP_004735959.1 340617506 10974462 complement(1801422..1801889) 1 NC_015844.1 Conserved protein belonging to the CYTH family; Localized in the cytoplasm; Family membership; CYTH family protein 1801889 10974462 zobellia_1515 Zobellia galactanivorans CYTH family protein YP_004735959.1 1801422 R 63186 CDS YP_004735960.1 340617507 10974463 complement(1801882..1802556) 1 NC_015844.1 The protein yraR belongs to the NAD dependent epimerase/dehydratase family, but its exact function is unknown. Features a N-terminal transmembrane helix. Localized in the cytoplasmic membrane.; Function unclear; protein yraR 1802556 yraR 10974463 yraR Zobellia galactanivorans protein yraR YP_004735960.1 1801882 R 63186 CDS YP_004735961.1 340617508 10978792 1802585..1803685 1 NC_015844.1 The DNA polymerase IV is a poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. It copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from polIII; Induced by SOS response; Contains a umuC domain; Localized in the cytoplasm; High confidence in function and specificity; DNA polymerase IV 1803685 dinB1 10978792 dinB1 Zobellia galactanivorans DNA polymerase IV YP_004735961.1 1802585 D 63186 CDS YP_004735962.1 340617509 10977744 1803917..1804738 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 1804738 10977744 zobellia_1518 Zobellia galactanivorans AraC family transcriptional regulator YP_004735962.1 1803917 D 63186 CDS YP_004735963.1 340617510 10974464 1804814..1807288 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations. Contains a carboxypeptidase regulatory domain (21-93) and the Plug module (120-217) acting as a channel gate. The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 1807288 10974464 zobellia_1519 Zobellia galactanivorans TonB-dependent Receptor YP_004735963.1 1804814 D 63186 CDS YP_004735964.1 340617511 10974465 complement(1807352..1807756) 1 NC_015844.1 Protein Localized in the cytoplasm; hypothetical protein 1807756 10974465 zobellia_1520 Zobellia galactanivorans hypothetical protein YP_004735964.1 1807352 R 63186 CDS YP_004735965.1 340617512 10974467 complement(1807760..1808740) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase) encoded by a different gene of those that encode for the ABC transporter permease component (ABC membrane); Family membership; ABC transporter ATPase 1808740 10974467 zobellia_1521 Zobellia galactanivorans ABC transporter ATPase YP_004735965.1 1807760 R 63186 CDS YP_004735966.1 340617513 10974468 complement(1808812..1810962) 1 NC_015844.1 Prolyl oligopeptidase cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. Has an absolute requirement for an X-Pro bond in the trans configuration immediately preceding the Pro-Y scissible bond; Belongs to the family S9 of the peptidases; Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; High confidence in function and specificity; prolyl oligopeptidase, family S9 1810962 10974468 zobellia_1522 Zobellia galactanivorans prolyl oligopeptidase, family S9 YP_004735966.1 1808812 R 63186 CDS YP_004735967.1 340617514 10974469 complement(1811061..1812050) 1 NC_015844.1 Aspartate-semialdehyde dehydrogenase is a homodimer involved in the biosynthesis of various amino acids from aspartate (L-lysine, L-methionine and L-threonine. It converts the L-aspartate 4-semialdehyde into L-4-aspartyl phosphate; Contains a N-terminal NADP-binding domain (Rossmann fold) and a C-terminal dimerization domain; Localized in the cytoplasm; High confidence in function and specificity; aspartate-semialdehyde dehydrogenase 1812050 asdA 10974469 asdA Zobellia galactanivorans aspartate-semialdehyde dehydrogenase YP_004735967.1 1811061 R 63186 CDS YP_004735968.1 340617515 10977555 complement(1812257..1812661) 1 NC_015844.1 The large-conductance mechanosensitive channel participates in the regulation of changes of osmotic pressure within the cell by openning, in response to stretch forces in the membrane lipid bilayer, at a pressure just below that which would cause cell disruption and death. It is a pentamer that forms a nonselective ion channel of 2.5 nanosiemens conductance; Contains two transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; Large-conductance mechanosensitive channel 1812661 mscL 10977555 mscL Zobellia galactanivorans Large-conductance mechanosensitive channel YP_004735968.1 1812257 R 63186 CDS YP_004735969.1 340617516 10978191 complement(1812745..1813857) 1 NC_015844.1 Alanine racemase plays a role in providing the D-alanine required for bacterial cell wall biosynthesis by isomerising L-alanine to D-alanine. Alanine racemase forms a homodimer; Uses the pyridoxal 5'-phosphate as cofactor; Localized in the cytoplasm; High confidence in function and specificity; alanine racemase 1813857 alrA 10978191 alrA Zobellia galactanivorans alanine racemase YP_004735969.1 1812745 R 63186 CDS YP_004735970.1 340617517 10977508 complement(1813835..1814488) 1 NC_015844.1 Thymidine kinase is an ubiquitous enzyme that catalyzes the ATP-dependent phosphorylation of thymidine; Localized in the cytoplasm; High confidence in function and specificity; thymidine kinase 1814488 tdkA 10977508 tdkA Zobellia galactanivorans thymidine kinase YP_004735970.1 1813835 R 63186 CDS YP_004735971.1 340617518 10978643 1814660..1815370 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1815370 10978643 zobellia_1527 Zobellia galactanivorans hypothetical protein YP_004735971.1 1814660 D 63186 CDS YP_004735972.1 340617519 10974470 1815488..1815844 1 NC_015844.1 Contains four transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1815844 10974470 zobellia_1528 Zobellia galactanivorans membrane protein YP_004735972.1 1815488 D 63186 CDS YP_004735973.1 340617520 10974471 1815850..1816521 1 NC_015844.1 Enzyme that uses S-AdoMet in the methylation of diverse substrates; Belongs to the UPF0011 family; Localized in the cytoplasm; Specificity unclear; methyltransferase 1816521 10974471 zobellia_1529 Zobellia galactanivorans methyltransferase YP_004735973.1 1815850 D 63186 CDS YP_004735974.1 340617521 10974472 1816527..1816871 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1816871 10974472 zobellia_1530 Zobellia galactanivorans hypothetical protein YP_004735974.1 1816527 D 63186 CDS YP_004735975.1 340617522 10974474 1816877..1817455 1 NC_015844.1 Conserved hypothetical protein distantly related to the Uracil-DNA glycosylase superfamily; Localized in the cytoplasm; hypothetical protein 1817455 10974474 zobellia_1531 Zobellia galactanivorans hypothetical protein YP_004735975.1 1816877 D 63186 CDS YP_004735976.1 340617523 10974475 1817640..1818068 1 NC_015844.1 Protein Localized in the cytoplasm; Family membership; hypothetical protein 1818068 10974475 zobellia_1532 Zobellia galactanivorans hypothetical protein YP_004735976.1 1817640 D 63186 CDS YP_004735977.1 340617524 10974476 1818143..1818499 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1818499 10974476 zobellia_1533 Zobellia galactanivorans hypothetical protein YP_004735977.1 1818143 D 63186 CDS YP_004735978.1 340617525 10974477 1818775..1820463 1 NC_015844.1 RecJ is a 5'-3' single-strand DNA exonuclease. Required for many types of recombinational events, although the stringency of the requirement for recJ appears to vary with the type of recombinational event monitored and the other recombination gene products which are available; Localized in the cytoplasm; High confidence in function and specificity; single-stranded-DNA-specific exonuclease RecJ 1820463 recJ 10974477 recJ Zobellia galactanivorans single-stranded-DNA-specific exonuclease RecJ YP_004735978.1 1818775 D 63186 CDS YP_004735979.1 340617526 10978444 1820460..1820846 1 NC_015844.1 Protein belonging to the Glyoxalase superfamily; Localized in the cytoplasm; Family membership; glyoxalase superfamily protein 1820846 10978444 zobellia_1535 Zobellia galactanivorans glyoxalase superfamily protein YP_004735979.1 1820460 D 63186 CDS YP_004735980.1 340617527 10974478 1821178..1822437 1 NC_015844.1 The Major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients. The specificity of this transporter is not known; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; major facilitator superfamily transporter 1822437 10974478 zobellia_1536 Zobellia galactanivorans major facilitator superfamily transporter YP_004735980.1 1821178 D 63186 CDS YP_004735981.1 340617528 10974479 complement(1822427..1823200) 1 NC_015844.1 Conserved protein belonging to the metallophosphoesterase family. The most conserved regions in this superfamily centre around the metal chelating residues. Distantly related to UDP-2,3-diacylglucosamine hydrolase (LpxH), which is involved in lipid A biosynthesis; Localized in the cytoplasm; Family membership; metallophosphoesterase family protein 1823200 10974479 zobellia_1537 Zobellia galactanivorans metallophosphoesterase family protein YP_004735981.1 1822427 R 63186 CDS YP_004735982.1 340617529 10974480 complement(1823240..1823692) 1 NC_015844.1 6-Pyruvoyl tetrahydrobiopterin synthase catalyses the conversion of dihydroneopterin triphosphate to 6-pyruvoyl tetrahydropterin, the second of three enzymatic steps in the synthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin is the cofactor for several aromatic amino acid monooxygenases. The enzyme is a homohexameric, composed of a dimer of trimers. A transition metal binding site formed by the three histidine residues is present in each subunit, and bound Zn(II) is responsible for the enzymatic activity; Localized in the cytoplasm; High confidence in function and specificity; 6-Pyruvoyl tetrahydrobiopterin synthase 1823692 ptsA 10974480 ptsA Zobellia galactanivorans 6-Pyruvoyl tetrahydrobiopterin synthase YP_004735982.1 1823240 R 63186 CDS YP_004735983.1 340617530 10978400 1823780..1824421 1 NC_015844.1 Prolyl 4-hydroxylase is a dioxygenase, requiring 2-oxoglutarate, dioxygen as cosubstrates and ferrous iron as a cofactor. The iron ion is bound by three conserved residues (HxD and H). Prokaryotic enzymes might catalyze hydroxylation of antibiotic peptides; Localized in the cytoplasm; Specificity unclear; prolyl 4-hydroxylase 1824421 10978400 zobellia_1539 Zobellia galactanivorans prolyl 4-hydroxylase YP_004735983.1 1823780 D 63186 CDS YP_004735984.1 340617531 10974481 complement(1824598..1825365) 1 NC_015844.1 Enoyl-CoA hydratase (ECH) and 3-2trans-enoyl-CoA isomerase (ECI) are two enzymes involved in fatty acid metabolism.; Family membership; enoyl-CoA hydratase/isomerase family 1825365 10974481 zobellia_1540 Zobellia galactanivorans enoyl-CoA hydratase/isomerase family YP_004735984.1 1824598 R 63186 CDS YP_004735985.1 340617532 10974482 complement(1825405..1826739) 1 NC_015844.1 Contains 12 transmembrane segments; Belongs to the multi antimicrobial extrusion (MATE) family; Localized in the cytoplasmic membrane; Family membership; multi antimicrobial extrusion family protein 1826739 10974482 zobellia_1541 Zobellia galactanivorans multi antimicrobial extrusion family protein YP_004735985.1 1825405 R 63186 CDS YP_004735986.1 340617533 10974483 complement(1826750..1827250) 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 1827250 10974483 zobellia_1542 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004735986.1 1826750 R 63186 CDS YP_004735987.1 340617534 10974484 1827302..1828102 1 NC_015844.1 Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains one N-terminal copy of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS-box proteins and bind to DNA; Localized in the cytoplasm; Family membership; universal stress protein 1828102 10974484 zobellia_1543 Zobellia galactanivorans universal stress protein YP_004735987.1 1827302 D 63186 CDS YP_004735988.1 340617535 10974027 1828750..1832643 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Probably localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 1832643 10974027 zobellia_1545 Zobellia galactanivorans one-component system sensor protein YP_004735988.1 1828750 D 63186 CDS YP_004735989.1 340617536 10974486 1832912..1833793 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; this protein contains a C- terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal GAF domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 1833793 10974486 zobellia_1546 Zobellia galactanivorans AraC family transcriptional regulator YP_004735989.1 1832912 D 63186 CDS YP_004735990.1 340617537 10974487 1834010..1834618 1 NC_015844.1 Conserved hypothetical protein including an N-terminal region rich in glycine, reminiscent of the collagen triple helix repeats (GxxG); Contains a prokaryotic lipoprotein signal peptide cleavage between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1834618 10974487 zobellia_1547 Zobellia galactanivorans lipoprotein YP_004735990.1 1834010 D 63186 CDS YP_004735991.1 340617538 10974488 1834763..1835386 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1835386 10974488 zobellia_1548 Zobellia galactanivorans periplasmic protein YP_004735991.1 1834763 D 63186 CDS YP_004735992.1 340617539 10974489 complement(1835694..1836896) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains a GAF domain; Possibly localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 1836896 10974489 zobellia_1549 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004735992.1 1835694 R 63186 CDS YP_004735993.1 340617540 10974490 complement(1837058..1837153) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1837153 10974490 zobellia_1550 Zobellia galactanivorans hypothetical protein YP_004735993.1 1837058 R 63186 CDS YP_004735994.1 340617541 10974491 complement(1837214..1838485) 1 NC_015844.1 Conserved protein involved in exopolysaccharide biosynthesis. Its exact function is unknown. Contains four transmembrane helices; Localized in the cytoplasmic membrane; Function unclear; exopolysaccharide production protein 1838485 10974491 zobellia_1551 Zobellia galactanivorans exopolysaccharide production protein YP_004735994.1 1837214 R 63186 CDS YP_004735995.1 340617542 10974492 complement(1838675..1838905) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1838905 10974492 zobellia_1552 Zobellia galactanivorans hypothetical protein YP_004735995.1 1838675 R 63186 CDS YP_004735996.1 340617543 10974493 complement(1839054..1840319) 1 NC_015844.1 Permease belonging to the Nucleobase Cation Symporter-1 (NCS1) family, which includes transporters for purines, pyrimidines and allantoin. It functions in uptake by substrate:H+ symport mechanism; Contains twelve transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; nucleobase cation symporter 1840319 10974493 zobellia_1553 Zobellia galactanivorans nucleobase cation symporter YP_004735996.1 1839054 R 63186 CDS YP_004735997.1 340617544 10974494 complement(1840330..1841775) 1 NC_015844.1 Xaa-His dipeptidase, also known as aminoacyl-histidine dipeptidase, catalyzes the hydrolysis of Xaa-|-His dipeptides. This dipeptidase has specificity for the unusual dipeptide beta-alanyl-L-histidine. PepD binds two co-catalytic zinc ions that activate the catalytic water molecule; Belongs to the family M20 of the metallopeptidase; Localized in the cytoplasm; High confidence in function and specificity; Xaa-His dipeptidase, family M20 1841775 pepD1 10974494 pepD1 Zobellia galactanivorans Xaa-His dipeptidase, family M20 YP_004735997.1 1840330 R 63186 CDS YP_004735998.1 340617545 10978325 complement(1841775..1843043) 1 NC_015844.1 Permease belonging to the Nucleobase Cation Symporter-1 (NCS1) family, which includes transporters for purines, pyrimidines and allantoin. It functions in uptake by substrate:H+ symport mechanism; Contains twelve transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; nucleobase cation symporter 1843043 10978325 zobellia_1555 Zobellia galactanivorans nucleobase cation symporter YP_004735998.1 1841775 R 63186 CDS YP_004735999.1 340617546 10974495 complement(1843043..1844095) 1 NC_015844.1 This protein belongs to the family 29 of the metallopeptidases, but lacks some of the catalytic or metal-binding residues; Localized in the cytoplasm; Function unclear; Non-peptidase protein 1844095 10974495 zobellia_1556 Zobellia galactanivorans Non-peptidase protein YP_004735999.1 1843043 R 63186 CDS YP_004736000.1 340617547 10974496 complement(1844130..1846451) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (20-89) and the Plug module (117-223) acting as a channel gate; The signal peptide is cleaved between the residues 17 and 18; Family membership; TonB-dependent Receptor 1846451 10974496 zobellia_1557 Zobellia galactanivorans TonB-dependent Receptor YP_004736000.1 1844130 R 63186 CDS YP_004736001.1 340617548 10974497 1846572..1847807 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 1847807 10974497 zobellia_1558 Zobellia galactanivorans hypothetical protein YP_004736001.1 1846572 D 63186 CDS YP_004736002.1 340617549 10974498 1847954..1849246 1 NC_015844.1 Contains twelve transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1849246 10974498 zobellia_1559 Zobellia galactanivorans membrane protein YP_004736002.1 1847954 D 63186 CDS YP_004736003.1 340617550 10974499 1849243..1850412 1 NC_015844.1 Conserved oxidoreductase using FAD as cofactor. Contains two structural domains, a N-terminal beta/beta/alpha sandwich domain and a C-terminal alpha+beta fold domain. Localized in the cytoplasm.; Specificity unclear; FAD-dependent oxidoreductase 1850412 10974499 zobellia_1560 Zobellia galactanivorans FAD-dependent oxidoreductase YP_004736003.1 1849243 D 63186 CDS YP_004736004.1 340617551 10974500 1850405..1851082 1 NC_015844.1 Conserved hydrolase belonging to the haloacid dehalogenase family, which includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. The structure consists of two domains, a four helix bundle domain and a alpha/beta domain. Localized in the cytoplasm.; Family membership; haloacid dehalogenase-like hydrolase 1851082 10974500 zobellia_1561 Zobellia galactanivorans haloacid dehalogenase-like hydrolase YP_004736004.1 1850405 D 63186 CDS YP_004736005.1 340617552 10974501 complement(1851174..1851740) 1 NC_015844.1 Transcriptional regulator featuring a N-terminal helix-turn-helix DNA binding motif belonging to the Xre family and a C-terminal domain adopting a Cupin barrel fold. Localized in the cytoplasm.; Specificity unclear; XRE family transcriptional regulator 1851740 10974501 zobellia_1562 Zobellia galactanivorans XRE family transcriptional regulator YP_004736005.1 1851174 R 63186 CDS YP_004736006.1 340617553 10974502 1852014..1855232 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations. Contains a carboxypeptidase regulatory domain (22-96) and the Plug module (112-241) acting as a channel gate; The signal peptide is cleaved between the residues 17 and 18; Family membership; TonB-dependent Receptor 1855232 10974502 zobellia_1563 Zobellia galactanivorans TonB-dependent Receptor YP_004736006.1 1852014 D 63186 CDS YP_004736007.1 340617554 10974503 1855262..1856707 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 1856707 10974503 zobellia_1564 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736007.1 1855262 D 63186 CDS YP_004736008.1 340617555 10974504 1856790..1858436 1 NC_015844.1 Protein containing a N-terminal Type I phosphodiesterase domain and a C-terminal PA14 domain. These enzymes catalyze the cleavage of phosphodiester and phosphosulphate bonds in various compounds such as NAD, deoxynucleotides and nucleotide sugars. The PA14 domain sequence suggests a binding function, rather than a catalytic role and its distribution is compatible with carbohydrate binding; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasm; Family membership; type I phosphodiesterase 1858436 10974504 zobellia_1565 Zobellia galactanivorans type I phosphodiesterase YP_004736008.1 1856790 D 63186 CDS YP_004736009.1 340617556 10974505 1858437..1859708 1 NC_015844.1 Protein belonging to the Metallo-beta-lactamase superfamily. This superfamily includes various zinc-dependent hydrolases. The residues involved in metal ion binding are strictly conserved in this protein; Localized in the cytoplasm; Family membership; metallohydrolase 1859708 10974505 zobellia_1566 Zobellia galactanivorans metallohydrolase YP_004736009.1 1858437 D 63186 CDS YP_004736010.1 340617557 10974506 1859695..1861053 1 NC_015844.1 Aminotransferases share certain mechanistic features with other pyridoxalphosphate-dependent enzymes, such as the covalent binding of the pyridoxalphosphate group to a lysine residue; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; Family membership; class-III aminotransferase 1861053 10974506 zobellia_1567 Zobellia galactanivorans class-III aminotransferase YP_004736010.1 1859695 D 63186 CDS YP_004736011.1 340617558 10974507 1861067..1862662 1 NC_015844.1 Protein containing a N-terminal Fibronectin type III domain, a central metallophosphoesterase domain and a second Fibronectin type III domain at the C-terminus. The most conserved regions in the metallophosphoesterase family centre around the metal chelating residues; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Family membership; metallophosphoesterase 1862662 10974507 zobellia_1568 Zobellia galactanivorans metallophosphoesterase YP_004736011.1 1861067 D 63186 CDS YP_004736012.1 340617559 10974508 1862659..1863741 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasm; Conserved hypothetical protein; periplasmic protein 1863741 10974508 zobellia_1569 Zobellia galactanivorans periplasmic protein YP_004736012.1 1862659 D 63186 CDS YP_004736013.1 340617560 10974509 1864001..1864108 1 NC_015844.1 Hypothetical protein; hypothetical protein 1864108 10974509 zobellia_1570 Zobellia galactanivorans hypothetical protein YP_004736013.1 1864001 D 63186 CDS YP_004736014.1 340617561 10974511 1864123..1864986 1 NC_015844.1 Conserved protein belonging to the metallophosphoesterase family. The most conserved regions in this superfamily centre around the metal chelating residues; Localized in the cytoplasm; Family membership; metallophosphoesterase 1864986 10974511 zobellia_1571 Zobellia galactanivorans metallophosphoesterase YP_004736014.1 1864123 D 63186 CDS YP_004736015.1 340617562 10974512 1865009..1866022 1 NC_015844.1 The Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; Belongs to the family 1 of the glycosyltransferases (GT1); Localized in the cytoplasm; Specificity unclear; glycosyltransferase 1866022 10974512 zobellia_1572 Zobellia galactanivorans glycosyltransferase YP_004736015.1 1865009 D 63186 CDS YP_004736016.1 340617563 10974513 1866023..1867438 1 NC_015844.1 Beta-glucosidases catalyze the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose; Belongs to the family 1 of the glycoside hydrolases (GH1) and adopts a (beta/alpha)8 barrel fold; Localized in the cytoplasm; High confidence in function and specificity; beta-glucosidase 1867438 bglA 10974513 bglA Zobellia galactanivorans beta-glucosidase YP_004736016.1 1866023 D 63186 CDS YP_004736017.1 340617564 10977599 complement(1867655..1868950) 1 NC_015844.1 This protein is the large permease component of a tripartite ATP-independent periplasmic (TRAP) transport system that comprises an extracytoplasmic solute receptor protein and two transmembrane proteins. TRAP transporters are secondary carriers that use an electrochemical H+ gradient as the driving force for transport; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; TRAP transporter large permease subunit 1868950 10977599 zobellia_1574 Zobellia galactanivorans TRAP transporter large permease subunit YP_004736017.1 1867655 R 63186 CDS YP_004736018.1 340617565 10974514 complement(1868956..1869414) 1 NC_015844.1 This protein is the small permease component of a tripartite ATP-independent periplasmic (TRAP) transport system that comprises an extracytoplasmic solute receptor protein and two transmembrane proteins. TRAP transporters are secondary carriers that use an electrochemical H+ gradient as the driving force for transport; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; TRAP transporter small permease subunit 1869414 10974514 zobellia_1575 Zobellia galactanivorans TRAP transporter small permease subunit YP_004736018.1 1868956 R 63186 CDS YP_004736019.1 340617566 10974515 complement(1869416..1870396) 1 NC_015844.1 This protein is the substrate-binding periplasmic subunit component of a tripartite ATP-independent periplasmic (TRAP) transport system that comprises an extracytoplasmic solute receptor protein and two transmembrane proteins. TRAP transporters are secondary carriers that use an electrochemical H+ gradient as the driving force for transport; Signal peptide of lipoprotein cleaved between the residues 19 and 20; Localized in the periplasmic space; Specificity unclear; TRAP transporter substrate-binding periplasmic subunit 1870396 10974515 zobellia_1576 Zobellia galactanivorans TRAP transporter substrate-binding periplasmic subunit YP_004736019.1 1869416 R 63186 CDS YP_004736020.1 340617567 10974516 complement(1870408..1871862) 1 NC_015844.1 Uronate isomerase catalyzes the reaction D-glucuronate to D-fructuronate and also converts D-galacturonate to D-tagaturonate. It is involved in the pentose and glucuronate interconversion. Localized in the cytoplasm.; High confidence in function and specificity; uronate isomerase 1871862 uxaC 10974516 uxaC Zobellia galactanivorans uronate isomerase YP_004736020.1 1870408 R 63186 CDS YP_004736021.1 340617568 10978738 1872116..1872826 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 1872826 10978738 zobellia_1578 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004736021.1 1872116 D 63186 CDS YP_004736022.1 340617569 10974517 complement(1872848..1875604) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1875604 10974517 zobellia_1579 Zobellia galactanivorans hypothetical protein YP_004736022.1 1872848 R 63186 CDS YP_004736023.1 340617570 10974518 complement(1875668..1877026) 1 NC_015844.1 This protein contains a N-terminal domain of unknown function followed by five Thrombospondin type 3 repeats and a C-terminal OmpA-like domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space and/or in outer membrane; Family membership; OmpA-like periplasmic protein 1877026 10974518 zobellia_1580 Zobellia galactanivorans OmpA-like periplasmic protein YP_004736023.1 1875668 R 63186 CDS YP_004736024.1 340617571 10974520 complement(1877140..1878333) 1 NC_015844.1 Enzyme involved in the Glycine, serine and threonine metabolism, and in particular, in the glycine catabolism; Also called 2-amino-3-ketobutyrate coenzyme A ligase; Uses the Pyridoxal phosphate as cofactor; Belongs to the class II of the pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity; glycine C-acetyltransferase 1878333 kblA2 10974520 kblA2 Zobellia galactanivorans glycine C-acetyltransferase YP_004736024.1 1877140 R 63186 CDS YP_004736025.1 340617572 10978050 complement(1878345..1881497) 1 NC_015844.1 The Exonuclease V is a multifunctional nuclease required for efficient DNA repair. It catalyzes the unwinding of double-stranded DNA and the cleavage of single-stranded DNA and it stimulates local genetic recombination. All of these activities require concomitant hydrolysis of ATP; Belongs to the helicase family, UvrD subfamily; Localized in the cytoplasm; High confidence in function and specificity; exodeoxyribonuclease V subunit beta 1881497 recB 10978050 recB Zobellia galactanivorans exodeoxyribonuclease V subunit beta YP_004736025.1 1878345 R 63186 CDS YP_004736026.1 340617573 10978440 1881571..1882179 1 NC_015844.1 Manganese superoxide dismutase destroys radicals which are normally produced within the cells and which are toxic to biological systems. It catalyzes the reaction: superoxide + 2 H+ = O2 + H2O2. SodA features an alpha N-terminal domain and an alpha/beta C-terminal domain, connected by a loop. It forms a homodimer and binds one manganese ion by subunit. Localized in the cytoplasm.; High confidence in function and specificity; superoxide dismutase 1882179 sodA 10978440 sodA Zobellia galactanivorans superoxide dismutase YP_004736026.1 1881571 D 63186 CDS YP_004736027.1 340617574 10978601 1882805..1883104 1 NC_015844.1 Hypothetical protein; hypothetical protein 1883104 10978601 zobellia_1584 Zobellia galactanivorans hypothetical protein YP_004736027.1 1882805 D 63186 CDS YP_004736028.1 340617575 10974521 complement(1883379..1885277) 1 NC_015844.1 Amidophosphoribosyltransferase catalyzes the first step in purine biosynthesis: 5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O. PurF belongs to the Class-II glutamine amidotransferase family. It forms a homotetramer and binds one magnesium ion per subunit. Localized in the cytoplasm.; High confidence in function and specificity; amidophosphoribosyltransferase 1885277 purF 10974521 purF Zobellia galactanivorans amidophosphoribosyltransferase YP_004736028.1 1883379 R 63186 CDS YP_004736029.1 340617576 10978408 complement(1885323..1886249) 1 NC_015844.1 Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group; Belongs to the Carbohydrate kinase PfkB family, Ribokinase subfamily, group C; Localized in the cytoplasm; Family membership; carbohydrate kinase 1886249 10978408 zobellia_1586 Zobellia galactanivorans carbohydrate kinase YP_004736029.1 1885323 R 63186 CDS YP_004736030.1 340617577 10974522 complement(1886313..1886432) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1886432 10974522 zobellia_1587 Zobellia galactanivorans hypothetical protein YP_004736030.1 1886313 R 63186 CDS YP_004736031.1 340617578 10974523 complement(1886465..1887100) 1 NC_015844.1 Ribonuclease H (RNase H) is a non-specific endoribonuclease that cleaves the 3'-O-P-bond of RNA strands in RNA/DNA hybrids. In DNA replication of prokaryotes, It helps to specify the origin of genomic replication by suppressing initiation at origins other than the oriC locus. It cleaves the RNA primer to produce a 3OH extremity and to allow initiation of the replication by DNA PolIII. It also could be involved in processing of R loops to modulate replication initiation and restore DNA topology ; Contains a RNA/DNA hybrid binding domain (RHBD) N-terminal to the catalytic domain that belongs to the ribosomal protein L9 family; Binds 2 metal ions (manganese or magnesium); Localized in the cytoplasm; High confidence in function and specificity; ribonuclease H 1887100 rnhA 10974523 rnhA Zobellia galactanivorans ribonuclease H YP_004736031.1 1886465 R 63186 CDS YP_004736032.1 340617579 10978481 complement(1887100..1887669) 1 NC_015844.1 Phosphoribosylglycinamide formyltransferase catalyzes the third step in de novo purine biosynthesis, the transfer of a formyl group to 5'-phosphoribosylglycinamide. Localized in the cytoplasm.; High confidence in function and specificity; phosphoribosylglycinamide formyltransferase 1887669 purN 10978481 purN Zobellia galactanivorans phosphoribosylglycinamide formyltransferase YP_004736032.1 1887100 R 63186 CDS YP_004736033.1 340617580 10978413 1887830..1888063 1 NC_015844.1 Acyl carrier protein (ACP) is the carrier of the growing fatty acid chain in fatty acid biosynthesis. ACP is produced as an apoprotein and is converted to its active form by [ACP]synthase (AcpS); Localized in the cytoplasm; High confidence in function and specificity; acyl carrier protein 1888063 acpP1 10978413 acpP1 Zobellia galactanivorans acyl carrier protein YP_004736033.1 1887830 D 63186 CDS YP_004736034.1 340617581 10977465 1888176..1889429 1 NC_015844.1 3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP synthase 1889429 fabB2 10977465 fabB2 Zobellia galactanivorans 3-oxoacyl-ACP synthase YP_004736034.1 1888176 D 63186 CDS YP_004736035.1 340617582 10977794 1889436..1890173 1 NC_015844.1 Ribonuclease III is an endoribonuclease that cleaves double-stranded RNA molecules to 5'- phosphomonoester. RNase III is involved in both rRNA processing and mRNA processing and decay; Localized in the cytoplasm; High confidence in function and specificity; ribonuclease III 1890173 rncA 10977794 rncA Zobellia galactanivorans ribonuclease III YP_004736035.1 1889436 D 63186 CDS YP_004736036.1 340617583 10978479 1890283..1890747 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1890747 10978479 zobellia_1593 Zobellia galactanivorans hypothetical protein YP_004736036.1 1890283 D 63186 CDS YP_004736037.1 340617584 10974525 1890751..1892181 1 NC_015844.1 Pyruvate kinase (PK) catalyzes the final step in glycolysis (Embden-Meyerhof pathway), the conversion of phosphoenolpyruvate to pyruvate with concomitant phosphorylation of ADP to ATP. PK forms a homotetramer and requires both magnesium and potassium ions for its activity. PK helps control the rate of glycolysis, along with phosphofructokinase and hexokinase. PK possesses allosteric sites for numerous effectors; Localized in the cytoplasm; High confidence in function and specificity; pyruvate kinase 1892181 pykA 10974525 pykA Zobellia galactanivorans pyruvate kinase YP_004736037.1 1890751 D 63186 CDS YP_004736038.1 340617585 10978416 complement(1892214..1892723) 1 NC_015844.1 Protein adopting a PAS fold. The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. PAS fold proteins are known to detect their signal by way of an associated cofactor (Haeme, flavin or 4-hydroxycinnamyl chromophore); Localized in the cytoplasm.; Function unclear; PAS fold sensor protein 1892723 10978416 zobellia_1595 Zobellia galactanivorans PAS fold sensor protein YP_004736038.1 1892214 R 63186 CDS YP_004736039.1 340617586 10974526 1892884..1893732 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 1893732 10974526 zobellia_1596 Zobellia galactanivorans AraC family transcriptional regulator YP_004736039.1 1892884 D 63186 CDS YP_004736040.1 340617587 10974527 1893824..1893976 1 NC_015844.1 Hypothetical protein; hypothetical protein 1893976 10974527 zobellia_1597 Zobellia galactanivorans hypothetical protein YP_004736040.1 1893824 D 63186 CDS YP_004736041.1 340617588 10974528 1894053..1894601 1 NC_015844.1 Protein belonging to the carboxymuconolactone decarboxylase family. Its exact function is unknown; Localized in the cytoplasm; Family membership; carboxymuconolactone decarboxylase family protein 1894601 10974528 zobellia_1598 Zobellia galactanivorans carboxymuconolactone decarboxylase family protein YP_004736041.1 1894053 D 63186 CDS YP_004736042.1 340617589 10974529 1894715..1895104 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1895104 10974529 zobellia_1599 Zobellia galactanivorans periplasmic protein YP_004736042.1 1894715 D 63186 CDS YP_004736043.1 340617590 10974530 complement(1895126..1895266) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1895266 10974530 zobellia_1600 Zobellia galactanivorans hypothetical protein YP_004736043.1 1895126 R 63186 CDS YP_004736044.1 340617591 10974533 1895544..1896002 1 NC_015844.1 This protein belongs to a family of putative small multi-drug export proteins; Contains three transmembrane helices; Localized in the cytoplasmic membrane; Family membership; putative small multi-drug export protein 1896002 10974533 zobellia_1601 Zobellia galactanivorans putative small multi-drug export protein YP_004736044.1 1895544 D 63186 CDS YP_004736045.1 340617592 10974534 complement(1896026..1896475) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1896475 10974534 zobellia_1602 Zobellia galactanivorans hypothetical protein YP_004736045.1 1896026 R 63186 CDS YP_004736046.1 340617593 10974535 complement(1896481..1898202) 1 NC_015844.1 Dihydroxy-acid dehydratase catalyzes the fourth step in the biosynthesis of isoleucine and valine, the dehydratation of 2,3-dihydroxy-isovaleic acid into alpha-ketoisovaleric acid; Binds a 4Fe-4S cluster; Localized in the cytoplasm; High confidence in function and specificity; dihydroxy-acid dehydratase 1898202 ilvD2 10974535 ilvD2 Zobellia galactanivorans dihydroxy-acid dehydratase YP_004736046.1 1896481 R 63186 CDS YP_004736047.1 340617594 10978033 complement(1898329..1899444) 1 NC_015844.1 FAD-dependent oxidoreductase of unknown substrate specificity; Localized in the cytoplasm; Specificity unclear; FAD-dependent oxidoreductase 1899444 10978033 zobellia_1604 Zobellia galactanivorans FAD-dependent oxidoreductase YP_004736047.1 1898329 R 63186 CDS YP_004736048.1 340617595 10974536 1899554..1901113 1 NC_015844.1 Hypothetical protein display three N-terminal Fibronectin type-III domains (FN3) and a C-terminal domain of unknown function. FN3 domains adopt a conserved beta sandwich fold also found in bacterial glycosyde hydrolases and other proteins; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 28 and 29; Localized in the outer membrane; Hypothetical protein; hypothetical protein 1901113 10974536 zobellia_1605 Zobellia galactanivorans hypothetical protein YP_004736048.1 1899554 D 63186 CDS YP_004736049.1 340617596 10974537 complement(1901178..1902530) 1 NC_015844.1 The biotin carboxylase is a part of the Acetyl-coenzyme A carboxylase complex that catalyzes the first step in long-chain fatty acid biosynthesis. the complex is a heterohexamer of biotin carboxyl carrier protein (accB), biotin carboxylase and two subunits each of carboxyl transferase subunit alpha (accA) and subunit beta (accD). First, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; Localized in the cytoplasm.; High confidence in function and specificity; acetyl-coenzyme A carboxylase, biotin carboxylase subunit 1902530 accC 10974537 accC Zobellia galactanivorans acetyl-coenzyme A carboxylase, biotin carboxylase subunit YP_004736049.1 1901178 R 63186 CDS YP_004736050.1 340617597 10977460 complement(1902616..1903107) 1 NC_015844.1 The biotin carboxyl carrier protein is a part of the Acetyl-coenzyme A carboxylase complex that catalyzes the first step in long-chain fatty acid biosynthesis. the complex is a heterohexamer of biotin carboxyl carrier protein , biotin carboxylase (accC) and two subunits each of carboxyl transferase subunit alpha (accA) and subunit beta (accD). First, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; Localized in the cytoplasm.; High confidence in function and specificity; acetyl-coenzyme A carboxylase, biotin carboxyl carrier protein subunit 1903107 accB 10977460 accB Zobellia galactanivorans acetyl-coenzyme A carboxylase, biotin carboxyl carrier protein subunit YP_004736050.1 1902616 R 63186 CDS YP_004736051.1 340617598 10977459 complement(1903142..1904134) 1 NC_015844.1 3-oxoacyl-[acyl-carrier-protein] synthase III, also known as beta-ketoacyl-ACP synthase III, catalyses the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Has some substrate specificity for acetyl-CoA. Its substrate specificity determines the biosynthesis of straight-chain of fatty acids instead of branched-chain. Negatively regulated by acyl-ACP, possibly by binding to either the free enzyme or the acyl-enzyme intermediate; Localzed in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP synthase III 1904134 fabH2 10977459 fabH2 Zobellia galactanivorans 3-oxoacyl-ACP synthase III YP_004736051.1 1903142 R 63186 CDS YP_004736052.1 340617599 10977806 1904147..1904242 1 NC_015844.1 Hypothetical protein; hypothetical protein 1904242 10977806 zobellia_1609 Zobellia galactanivorans hypothetical protein YP_004736052.1 1904147 D 63186 CDS YP_004736053.1 340617600 10974538 complement(1904314..1904511) 1 NC_015844.1 The ribosomal protein L32 is part of the large subunit (50S) of the ribosome; Belongs to the ribosomal protein L32p family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L32 1904511 rpmF 10974538 rpmF Zobellia galactanivorans 50S ribosomal protein L32 YP_004736053.1 1904314 R 63186 CDS YP_004736054.1 340617601 10978521 complement(1904519..1905043) 1 NC_015844.1 Conserved protein belonging to the family DUF177; Localized in the cytoplasm; Family membership; hypothetical protein 1905043 10978521 zobellia_1611 Zobellia galactanivorans hypothetical protein YP_004736054.1 1904519 R 63186 CDS YP_004736055.1 340617602 10974540 complement(1905204..1906250) 1 NC_015844.1 4-Hydroxythreonine-4-phosphate dehydrogenase is involved in the biosynthesis of pyridoxal phosphate. It catalyzes the NAD(P)-dependent oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate. PdxA is a dimer and binds 1 divalent metal cation per subunit. Can use ions such as zinc, magnesium or cobalt. The active site is located at the dimer interface. Localized in the cytoplasm.; High confidence in function and specificity; 4-hydroxythreonine-4-phosphate dehydrogenase 1906250 pdxA 10974540 pdxA Zobellia galactanivorans 4-hydroxythreonine-4-phosphate dehydrogenase YP_004736055.1 1905204 R 63186 CDS YP_004736056.1 340617603 10978319 1906310..1906906 1 NC_015844.1 Riboflavin synthase is an oligomer that consist of 3 alpha subunits and 60 beta subunits. It is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)- pyrimidinedione and L-3,4-dihydrohy-2-butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyzes the dismutation of 6,7-dimethyl-8-lumazine to riboflavin and 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)- pyrimidinedione. Localized in the cytoplasm.; High confidence in function and specificity; riboflavin synthase subunit alpha 1906906 ribE 10978319 ribE Zobellia galactanivorans riboflavin synthase subunit alpha YP_004736056.1 1906310 D 63186 CDS YP_004736057.1 340617604 10978462 complement(1906908..1910708) 1 NC_015844.1 Contains two central TPR motifs and a C-terminal transglutaminase-like domain; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1910708 10978462 zobellia_1614 Zobellia galactanivorans periplasmic protein YP_004736057.1 1906908 R 63186 CDS YP_004736058.1 340617605 10974541 1910934..1911350 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Hypothetical protein; hypothetical protein 1911350 10974541 zobellia_1615 Zobellia galactanivorans hypothetical protein YP_004736058.1 1910934 D 63186 CDS YP_004736059.1 340617606 10974542 complement(1911378..1913189) 1 NC_015844.1 Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains twelve transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sodium/solute symporter 1913189 10974542 zobellia_1616 Zobellia galactanivorans sodium/solute symporter YP_004736059.1 1911378 R 63186 CDS YP_004736060.1 340617607 10974543 1913273..1914028 1 NC_015844.1 Conserved integral membrane protein belonging to the DUF81 family; Contains eight transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 1914028 10974543 zobellia_1617 Zobellia galactanivorans membrane protein YP_004736060.1 1913273 D 63186 CDS YP_004736061.1 340617608 10974544 complement(1913991..1914236) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1914236 10974544 zobellia_1618 Zobellia galactanivorans hypothetical protein YP_004736061.1 1913991 R 63186 CDS YP_004736062.1 340617609 10974545 1914361..1916925 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1916925 10974545 zobellia_1619 Zobellia galactanivorans lipoprotein YP_004736062.1 1914361 D 63186 CDS YP_004736063.1 340617610 10974546 complement(1916930..1917991) 1 NC_015844.1 This enzyme is involved in the catabolism of aromatic (or chloroaromatic) compounds, derived from lignin, catechol or protocatechuate. Converts the 2,5-dihydro-5-oxofuran-2-acetate to cis,cis-hexadienedioate; Contains a N-terminal Enolase domain-like fold and a C-terminal TIM alpha/beta barrel fold; Belongs to the Mandelate racemase / muconate lactonizing enzyme family; Localized in the cytoplasm; Specificity unclear; muconate cycloisomerase 1917991 10974546 zobellia_1620 Zobellia galactanivorans muconate cycloisomerase YP_004736063.1 1916930 R 63186 CDS YP_004736064.1 340617611 10974547 complement(1917988..1919061) 1 NC_015844.1 Conserved protein belonging to the DUF1611 family; Localized in the cytoplasm; Family membership; hypothetical protein 1919061 10974547 zobellia_1621 Zobellia galactanivorans hypothetical protein YP_004736064.1 1917988 R 63186 CDS YP_004736065.1 340617612 10974548 complement(1919072..1920133) 1 NC_015844.1 The threonine synthase catalyzes the transformation of homoserine-phosphate into threonine; Uses the pyridoxal phosphate as cofactor (vitamin B6) attached to a conserved lysine residue; Belongs to the serine/threonine dehydratase family; Localized in the cytoplasm; High confidence in function and specificity; threonine synthase 1920133 thrC 10974548 thrC Zobellia galactanivorans threonine synthase YP_004736065.1 1919072 R 63186 CDS YP_004736066.1 340617613 10978658 complement(1920226..1921266) 1 NC_015844.1 Protein featuring five Kelch repeats. Kelch is a 50-residue motif, which forms a beta sheet. Several of these sheets associate to form a beta propeller structure; Contains a putative lipoprotein signal peptide cleaved between the residues 17 and 18; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 1921266 10978658 zobellia_1623 Zobellia galactanivorans membrane protein YP_004736066.1 1920226 R 63186 CDS YP_004736067.1 340617614 10974549 complement(1921305..1922744) 1 NC_015844.1 Conserved protein containing a C-terminal Rubredoxin-like domain. The most conserved feature of the rubredoxin-like domain is the cluster of four cysteines involved in iron binding (Cys-x-x-Cys-x(n)-Cys-x-x-Cys). This domain folds into a short three-stranded antiparallel beta-sheet and a number of loops; Localized in the cytoplasm; Family membership; Rubredoxin family protein 1922744 10974549 zobellia_1624 Zobellia galactanivorans Rubredoxin family protein YP_004736067.1 1921305 R 63186 CDS YP_004736068.1 340617615 10974550 complement(1922757..1926287) 1 NC_015844.1 Bifunctional enzyme involved in the denitrification processes (nitrate respiration). It contains in its N-terminal part a nitrate reductase module required for nitrate assimilation (reducing nitrate to nitrite) using molybdopterin and 1 4Fe-4S cluster as cofactors and in its C-terminal part a nitrite reductase module required for nitrite assimilation (reducing nitrite to ammonia) using FAD, 4Fe-4S cluster and siroheme as cofactors; Belongs to Belongs to the prokaryotic molybdopterin-containing oxidoreductase family and to the nitrite and sulfite reductase 4Fe-4S domain family; Localized in the cytoplasm; High confidence in function and specificity; respiratory nitrate/nitrite reductase 1926287 narB/nirB 10974550 narB/nirB Zobellia galactanivorans respiratory nitrate/nitrite reductase YP_004736068.1 1922757 R 63186 CDS YP_004736069.1 340617616 10978238 complement(1926431..1927774) 1 NC_015844.1 Cyclomaltodextrinase hydrolyzes cyclodextrins. Can also act on linear maltodextrins, with the exception of maltose. Belongs to the family GH13 of the glycoside hydrolases. Involved in starch/glycogen metabolism.; High confidence in function and specificity; cyclomaltodextrinase 1927774 10978238 zobellia_1626 Zobellia galactanivorans cyclomaltodextrinase YP_004736069.1 1926431 R 63186 CDS YP_004736070.1 340617617 10974551 complement(1927813..1928541) 1 NC_015844.1 Response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA- binding activity (here a LuxR-type HTH domain) that acts as transcriptional regulator; Family membership; two-component system-response regulator 1928541 10974551 zobellia_1627 Zobellia galactanivorans two-component system-response regulator YP_004736070.1 1927813 R 63186 CDS YP_004736071.1 340617618 10974552 complement(1928637..1929941) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 1929941 10974552 zobellia_1628 Zobellia galactanivorans periplasmic protein YP_004736071.1 1928637 R 63186 CDS YP_004736072.1 340617619 10974553 complement(1929977..1930801) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase) encoded by a different gene of those that encode for the ABC transporter permease component (ABC membrane); Probably part of a high-affinity binding-protein-dependent transport system for nitrate. Probably responsible for energy coupling to the transport system; Family membership; nitrate-specific ABC transporter ATPase 1930801 nrtC 10974553 nrtC Zobellia galactanivorans nitrate-specific ABC transporter ATPase YP_004736072.1 1929977 R 63186 CDS YP_004736073.1 340617620 10978274 complement(1930816..1931655) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase) encoded by a different gene of those that encode for the ABC transporter permease component (ABC membrane); Probably part of a high-affinity binding-protein-dependent transport system for nitrate. Probably responsible for energy coupling to the transport system; Family membership; nitrate-specific ABC transporter ATPase 1931655 nrtD 10978274 nrtD Zobellia galactanivorans nitrate-specific ABC transporter ATPase YP_004736073.1 1930816 R 63186 CDS YP_004736074.1 340617621 10978275 complement(1931677..1932777) 1 NC_015844.1 Probably part of a high-affinity binding-protein-dependent (BPD) transport system for nitrate; probably responsible for the translocation of the substrate across the membrane; Localized in the cytoplasmic membrane by six transmembrane segments; High confidence in function and specificity; nitrate-specific BPD transport permease 1932777 nrtB 10978275 nrtB Zobellia galactanivorans nitrate-specific BPD transport permease YP_004736074.1 1931677 R 63186 CDS YP_004736075.1 340617622 10978273 complement(1932817..1934202) 1 NC_015844.1 Essential component of the nitrate-transporting system. May be the substrate-binding protein; Lipoprotein putatively anchored in the outer membrane or in the cytoplasmic membrane (or in both membranes) by its N-terminal lipidic residue (peripheral membrane protein); High confidence in function and specificity; nitrate-specific BPD transport substrate-binding protein 1934202 nrtA 10978273 nrtA Zobellia galactanivorans nitrate-specific BPD transport substrate-binding protein YP_004736075.1 1932817 R 63186 CDS YP_004736076.1 340617623 10978272 complement(1934452..1935207) 1 NC_015844.1 This protein complexes with cAMP via an N-terminal cyclic nucleotide-binding domain and binds to specific DNA sites, via a C-terminal crp-type HTH domain, near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA; Family membership; cAMP-binding dependent transcriptionnal regulator 1935207 10978272 zobellia_1633 Zobellia galactanivorans cAMP-binding dependent transcriptionnal regulator YP_004736076.1 1934452 R 63186 CDS YP_004736077.1 340617624 10974554 complement(1935222..1936634) 1 NC_015844.1 Putatively involved in the uptake of nitrate or extrusion of nitrite; The proteins contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Function unclear; nitrate/nitrite-specific MFS transporter protein 1936634 10974554 zobellia_1634 Zobellia galactanivorans nitrate/nitrite-specific MFS transporter protein YP_004736077.1 1935222 R 63186 CDS YP_004736078.1 340617625 10974555 complement(1936910..1937725) 1 NC_015844.1 This enzyme catalyzes two sequential methylation reactions, forming precorrin-1 and precorrin-2 by methylations at C-2 and C-7 of uroporphyrinogen III respectively; It is the first enzyme specific to the cobalamin (vitamin B12) pathway and precorrin-2 is a common intermediate in the biosynthesis of corrinoids such as vitamin B12, siroheme and coenzyme F430; Belongs to the precorrin methyltransferase family; Localized in the cytoplasm; High confidence in function and specificity; uroporphyrin-III C-methyltransferase 1937725 cobA2 10974555 cobA2 Zobellia galactanivorans uroporphyrin-III C-methyltransferase YP_004736078.1 1936910 R 63186 CDS YP_004736079.1 340617626 10977666 1937808..1940324 1 NC_015844.1 Nitrite reductase, required for nitrite assimilation (reducing nitrite to ammonia), catalyzes the second step of nitrate assimilation (denitrification); Binds 1 siroheme and 1 2Fe-2S cluster, uses FAD as cofactor; It is an homodimer which associates with nirD; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family; Localized in the cytoplasm; High confidence in function and specificity; nitrite reductase, large subunit 1940324 nirB 10977666 nirB Zobellia galactanivorans nitrite reductase, large subunit YP_004736079.1 1937808 D 63186 CDS YP_004736080.1 340617627 10978252 1940402..1940779 1 NC_015844.1 Protein that consists of a Rieske domain; The rieske domain has a 2Fe-2S centre; Associates with NirB and is required for activity reductase of NirB; High confidence in function and specificity; nitrite reductase, small subunit 1940779 nirD 10978252 nirD Zobellia galactanivorans nitrite reductase, small subunit YP_004736080.1 1940402 D 63186 CDS YP_004736081.1 340617628 10978253 1940891..1941484 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 1941484 10978253 zobellia_1638 Zobellia galactanivorans hypothetical protein YP_004736081.1 1940891 D 63186 CDS YP_004736082.1 340617629 10974556 1941515..1943368 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two transmembrane segments and an N-terminal PAS/PAC domain involved in many signalling proteins where they are used as a signal sensor domain; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 1943368 10974556 zobellia_1639 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004736082.1 1941515 D 63186 CDS YP_004736083.1 340617630 10974557 1943355..1943939 1 NC_015844.1 This protein Catalyzes the dehydrogenation of precorrin-2 into siroheme that is the second step of the siroheme biosynthesis; This reaction consists of the NAD-dependent oxidation of precorrin-2 into sirohydrochlorin used as precursor in siroheme biosynthesis; Putatively also catalized the third step that is the conversion of sirohydrochlorin into siroheme; High confidence in function and specificity; precorrin-2 dehydrogenase 1943939 sirC 10974557 sirC Zobellia galactanivorans precorrin-2 dehydrogenase YP_004736083.1 1943355 D 63186 CDS YP_004736084.1 340617631 10978598 complement(1943961..1944416) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1944416 10978598 zobellia_1641 Zobellia galactanivorans membrane protein YP_004736084.1 1943961 R 63186 CDS YP_004736085.1 340617632 10974558 complement(1944534..1945547) 1 NC_015844.1 This protein is higly; Family membership; flavoprotein 1945547 10974558 zobellia_1642 Zobellia galactanivorans flavoprotein YP_004736085.1 1944534 R 63186 CDS YP_004736086.1 340617633 10974559 complement(1945712..1946734) 1 NC_015844.1 The LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of operons; They contain a N-terminal lacI-type HTH domain involved in the binding of the protein to the operator sequences in the DNA and a C- terminal periplasmic binding protein domain that are the primary receptors for chemotaxis and transport of many sugar based solutes that act as inducers; Localized in the cytoplasm; Family membership; LacI-type transcriptional regulator 1946734 10974559 zobellia_1643 Zobellia galactanivorans LacI-type transcriptional regulator YP_004736086.1 1945712 R 63186 CDS YP_004736087.1 340617634 10974560 complement(1946840..1946965) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1946965 10974560 zobellia_1644 Zobellia galactanivorans hypothetical protein YP_004736087.1 1946840 R 63186 CDS YP_004736088.1 340617635 10974561 complement(1947126..1947545) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1947545 10974561 zobellia_1645 Zobellia galactanivorans hypothetical protein YP_004736088.1 1947126 R 63186 CDS YP_004736089.1 340617636 10974562 1947646..1947918 1 NC_015844.1 Hypothetical protein; hypothetical protein 1947918 10974562 zobellia_1646 Zobellia galactanivorans hypothetical protein YP_004736089.1 1947646 D 63186 CDS YP_004736090.1 340617637 10974563 complement(1947901..1948623) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 1948623 10974563 zobellia_1647 Zobellia galactanivorans hypothetical protein YP_004736090.1 1947901 R 63186 CDS YP_004736091.1 340617638 10974564 complement(1948921..1949031) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1949031 10974564 zobellia_1648 Zobellia galactanivorans hypothetical protein YP_004736091.1 1948921 R 63186 CDS YP_004736092.1 340617639 10974565 1949035..1949151 1 NC_015844.1 Hypothetical protein; hypothetical protein 1949151 10974565 zobellia_1649 Zobellia galactanivorans hypothetical protein YP_004736092.1 1949035 D 63186 CDS YP_004736093.1 340617640 10974566 1949157..1949492 1 NC_015844.1 This transcription regulatory protein binds DNA via a helix-turn-helix (HTH) motif. The ArsR family includes several proteins that appear to dissociate from DNA in the presence of metal ions. Metal ion binding would induce a conformational change that would prevent the protein from binding DNA. This protein adopts a fold of five alpha-helices and a pair of antiparallel beta-strands. Most ArsR-like metalloregulators form homodimers. Localized in the cytoplasm.; Specificity unclear; ArsR-type transcriptional regulator 1949492 10974566 zobellia_1650 Zobellia galactanivorans ArsR-type transcriptional regulator YP_004736093.1 1949157 D 63186 CDS YP_004736094.1 340617641 10974568 1949576..1950583 1 NC_015844.1 This family of integral membrane proteins are predicted to be permeases of unknown specificity (DUF318 family); Contains eight transmembrane helices; Localized in the cytoplasmic membrane; Family membership; permease 1950583 10974568 zobellia_1651 Zobellia galactanivorans permease YP_004736094.1 1949576 D 63186 CDS YP_004736095.1 340617642 10974569 1950723..1950935 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 1950935 10974569 zobellia_1652 Zobellia galactanivorans hypothetical protein YP_004736095.1 1950723 D 63186 CDS YP_004736096.1 340617643 10974570 complement(1951166..1951654) 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 1951654 10974570 zobellia_1653 Zobellia galactanivorans hypothetical protein YP_004736096.1 1951166 R 63186 CDS YP_004736097.1 340617644 10974571 complement(1951717..1954716) 1 NC_015844.1 The type I restriction enzyme, Subunit R recognize specific short DNA sequences and cleaves at sites remote (1000 to 5000 bp) from the recognition sequence to give random double-stranded fragments with terminal 5'-phosphates. It is required for both endonuclease and ATPase activities, but not for modification; The Type I restriction and modification enzymes are complex, multifunctional systems composed of three polypeptides R, M and S and which require ATP, S-adenosyl methionine and magnesium as cofactors. In addition to their endonucleolytic and methylase activities, they are potent DNA-dependent ATPases; The sequence recognized by ZgaDII is unknown; Localized in the cytoplasm; High confidence in function and specificity; type I restriction enzyme ZgaDII, R subunit 1954716 HsdR2 10974571 HsdR2 Zobellia galactanivorans type I restriction enzyme ZgaDII, R subunit YP_004736097.1 1951717 R 63186 CDS YP_004736098.1 340617645 10977997 complement(1954713..1955984) 1 NC_015844.1 The Type I restriction enzyme S subunit dictates DNA sequences specificity; Contains two DNA recognition domains, each specifying recognition of one of the two defined components of the bipartite DNA target sequence; The type I restriction enzyme, M and S subunits together form a N-6 adenine methyltransferase (MTase) that methylates the amino group at the C-6 position of a adenine residue in a hemimethylated DNA recognition sequence, in order to prevent the host from digesting its own genome via its restriction enzyme; Localized in the cytoplasm; High confidence in function and specificity; type I restriction enzyme ZgaDII, S subunit 1955984 hsdS2 10977997 hsdS2 Zobellia galactanivorans type I restriction enzyme ZgaDII, S subunit YP_004736098.1 1954713 R 63186 CDS YP_004736099.1 340617646 10977999 complement(1956120..1957775) 1 NC_015844.1 This protein could be a transcriptional regulator containing an N-terminal HTH domain involved in the DNA binding; Contain a N-terminal AAA domain involved in the ATP binding; Localized in the cytoplasm; Family membership; putative transcriptional regulator 1957775 10977999 zobellia_1656 Zobellia galactanivorans putative transcriptional regulator YP_004736099.1 1956120 R 63186 CDS YP_004736100.1 340617647 10974572 complement(1957856..1959457) 1 NC_015844.1 The type I restriction enzyme, M and S subunits together form a N-6 adenine methyltransferase (MTase) that methylates the amino group at the C-6 position of a adenine residue in a hemimethylated bipartite DNA recognition sequence, in order to prevent the host from digesting its own genome via its restriction enzyme. It acts as a maintenance MTase modifying the DNA so that both strands become methylated. If the recognition sequence is unmethylated, in the presence of the R subunit, the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site; Localized in the cytoplasm; High confidence in function and specificity; type I restriction enzyme ZgaDII, M subunit 1959457 HsdM2 10974572 HsdM2 Zobellia galactanivorans type I restriction enzyme ZgaDII, M subunit YP_004736100.1 1957856 R 63186 CDS YP_004736101.1 340617648 10977995 complement(1959502..1959600) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1959600 10977995 zobellia_1658 Zobellia galactanivorans hypothetical protein YP_004736101.1 1959502 R 63186 CDS YP_004736102.1 340617649 10974573 1959666..1959881 1 NC_015844.1 Hypothetical protein; hypothetical protein 1959881 10974573 zobellia_1659 Zobellia galactanivorans hypothetical protein YP_004736102.1 1959666 D 63186 CDS YP_004736103.1 340617650 10974574 complement(1960073..1960297) 1 NC_015844.1 Conserved hypothetical protein belonging to the UPF0156 family; Localized in the cytoplasm; Family membership; hypothetical protein 1960297 10974574 zobellia_1660 Zobellia galactanivorans hypothetical protein YP_004736103.1 1960073 R 63186 CDS YP_004736104.1 340617651 10974028 complement(1960594..1960998) 1 NC_015844.1 Protein that belongs to the Glyoxalase superfamily protein Localized in the cytoplasm; Family membership; glyoxalase superfamily protein 1960998 10974028 zobellia_1662 Zobellia galactanivorans glyoxalase superfamily protein YP_004736104.1 1960594 R 63186 CDS YP_004736105.1 340617652 10974577 1961070..1961462 1 NC_015844.1 Ribosome-binding factor A associates with free 30S ribosomal subunits, but not with 30S subunits associates with the 50S subunits in the 70S ribosomes or polysomes. It essential for efficient processing of 16S rRNA and may interact with the 5'-terminal helix region of 16S rRNA; Localized in the cytoplasm; High confidence in function and specificity; ribosome-binding factor A 1961462 rbfA 10974577 rbfA Zobellia galactanivorans ribosome-binding factor A YP_004736105.1 1961070 D 63186 CDS YP_004736106.1 340617653 10978432 1961465..1962658 1 NC_015844.1 Protein distantly related to LolC, an permease involved in the ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 1962658 10978432 zobellia_1664 Zobellia galactanivorans membrane protein YP_004736106.1 1961465 D 63186 CDS YP_004736107.1 340617654 10974578 complement(1962670..1963665) 1 NC_015844.1 tRNA-dihydrouridine synthase B catalyzes the reduction of the 5,6-double bond of a uridine residue, resulting in the formation of dihydrouridine. This modified base is found in the D-loop of most tRNAs; Uses FAD as cofactor; Localized in the cytoplasm; High confidence in function and specificity; tRNA-dihydrouridine synthase B 1963665 dusB 10974578 dusB Zobellia galactanivorans tRNA-dihydrouridine synthase B YP_004736107.1 1962670 R 63186 CDS YP_004736108.1 340617655 10977771 1963733..1964500 1 NC_015844.1 Prolipoprotein diacylglyceryl transferase catalyzes the first step in lipoprotein biogenesis. It transfers the n-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins; Contains seven transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; prolipoprotein diacylglyceryl transferase 1964500 lgtA 10977771 lgtA Zobellia galactanivorans prolipoprotein diacylglyceryl transferase YP_004736108.1 1963733 D 63186 CDS YP_004736109.1 340617656 10978088 1964472..1965866 1 NC_015844.1 This protein belongs to the radical SAM family. These enzymes catalyze diverse reactions, including unusual methylations, isomerization, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation. They generate a radical species by reductive cleavage of S-adenosylmethionine (SAM) through an unusual Fe-S center; Localized in the cytoplasm; Family membership; Radical SAM family protein 1965866 10978088 zobellia_1667 Zobellia galactanivorans Radical SAM family protein YP_004736109.1 1964472 D 63186 CDS YP_004736110.1 340617657 10974579 1965884..1966048 1 NC_015844.1 Contains one C-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1966048 10974579 zobellia_1668 Zobellia galactanivorans membrane protein YP_004736110.1 1965884 D 63186 CDS YP_004736111.1 340617658 10974580 complement(1966059..1968461) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (23-99) and the Plug module (120-216) acting as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 1968461 10974580 zobellia_1669 Zobellia galactanivorans TonB-dependent Receptor YP_004736111.1 1966059 R 63186 CDS YP_004736112.1 340617659 10974581 1968610..1968708 1 NC_015844.1 Hypothetical protein; hypothetical protein 1968708 10974581 zobellia_1670 Zobellia galactanivorans hypothetical protein YP_004736112.1 1968610 D 63186 CDS YP_004736113.1 340617660 10974583 1968783..1970618 1 NC_015844.1 LepA is a GTP-binding protein. Quin and collaborators (Cell, 2006) have recently demonstrated that LepA is a third elongation factor required for accurate and efficient protein synthesis. LepA has the unique function of back-translocating posttranslocational ribosomes. It recognizes ribosomes after a defective translocation reaction and induces a back-translocation, thus giving the elongation factor EF-G a second chance to translocate the tRNAs correctly. Localized in the cytoplasm.; High confidence in function and specificity; elongation factor LepA 1970618 lepA 10974583 lepA Zobellia galactanivorans elongation factor LepA YP_004736113.1 1968783 D 63186 CDS YP_004736114.1 340617661 10978078 complement(1970677..1971243) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 1971243 10978078 zobellia_1672 Zobellia galactanivorans hypothetical protein YP_004736114.1 1970677 R 63186 CDS YP_004736115.1 340617662 10974584 1971302..1971538 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 1971538 10974584 zobellia_1673 Zobellia galactanivorans hypothetical protein YP_004736115.1 1971302 D 63186 CDS YP_004736116.1 340617663 10974585 complement(1971566..1973434) 1 NC_015844.1 Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. This integral membrane protein also contains a C-terminal TrkA- N domain which binds NAD and adopts a Rossmann fold, Contains twelve transmembrane helices; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter family; Localized in the cytoplasmic membrane; Specificity unclear; sodium/hydrogen exchanger 1973434 10974585 zobellia_1674 Zobellia galactanivorans sodium/hydrogen exchanger YP_004736116.1 1971566 R 63186 CDS YP_004736117.1 340617664 10974586 1973670..1975451 1 NC_015844.1 Na/H antiporters are key transporters in maintaining the pH of actively metabolising cells. The molecular mechanisms of antiport are unclear. This integral membrane protein also contains a C-terminal TrkA- N domain which binds NAD and adopts a Rossmann fold; Contains twelve transmembrane helices; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter family; Localized in the cytoplasmic membrane; Specificity unclear; sodium/hydrogen exchanger 1975451 10974586 zobellia_1675 Zobellia galactanivorans sodium/hydrogen exchanger YP_004736117.1 1973670 D 63186 CDS YP_004736118.1 340617665 10974587 complement(1975457..1975609) 1 NC_015844.1 Hypothetical protein; hypothetical protein 1975609 10974587 zobellia_1676 Zobellia galactanivorans hypothetical protein YP_004736118.1 1975457 R 63186 CDS YP_004736119.1 340617666 10974588 1975651..1976511 1 NC_015844.1 Conserved protein belonging to the metallo beta-lactamase superfamily. The histidine residues which coordinate the zinc ions are strictly conserved in this protein, suggesting that it is a metal-dependent hydrolase. But its exact function is still unknown; Localized in the cytoplasm; Function unclear; metal-dependent hydrolase 1976511 10974588 zobellia_1677 Zobellia galactanivorans metal-dependent hydrolase YP_004736119.1 1975651 D 63186 CDS YP_004736120.1 340617667 10974589 1976891..1978522 1 NC_015844.1 The Serine endopeptidases use a catalytic serine residue as a nucleophile and form an acyl intermediate. These peptidases can also readily act as transferases; Belongs to the families S8 of peptidases, clan SB; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the cytoplasmic and/or outer membrane; Family membership; serine endopeptidase 1978522 10974589 zobellia_1678 Zobellia galactanivorans serine endopeptidase YP_004736120.1 1976891 D 63186 CDS YP_004736121.1 340617668 10974590 1978528..1980387 1 NC_015844.1 Aminopeptidase catalyzes the hydrolysis of N-terminal amino-acid residues from oligopeptides or polypeptides. This enzyme belongs to the family M1 of the peptidases. A catalytic zinc ion is bound by two histidines and a glutamate. The histidines are within an 'HEXXH' motif on one long helix with the glutamate on another antiparallel helix. The catalytic mechanism is believed to involve activation of a water molecule by the zinc ion. The glutamate of the HEXXH motif is known to be important for catalysis and a tyrosine may also be involved. Features a signal peptide cleaved between the residues 21 and 22. Localized in the periplasm.; Specificity unclear; aminopeptidase 1980387 10974590 zobellia_1679 Zobellia galactanivorans aminopeptidase YP_004736121.1 1978528 D 63186 CDS YP_004736122.1 340617669 10974591 1980467..1980844 1 NC_015844.1 Ribonuclease P (RNaseP) consists of a catalytic RNA component (M1 or rnpB) and a protein subunit . RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. Localized in the cytoplasm.; High confidence in function and specificity; ribonuclease P protein component 1980844 rnpA 10974591 rnpA Zobellia galactanivorans ribonuclease P protein component YP_004736122.1 1980467 D 63186 CDS YP_004736123.1 340617670 10978484 1980910..1982541 1 NC_015844.1 This enzyme is a modular protein with a N-terminal PDZ domain, a central carboxy-terminal processing peptidase and a C-terminal domain of unknown function. The catalytic module belongs to the family S41 of the peptidase. It shows specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala, but then cleaves at a variable distance from the C- terminus. PDZ domains are multifunctional protein-protein interaction modules. In many cases, PDZ domains bind to a signature motif ([FYST]-X-[FVA]) occurring at the very C- terminus of target proteins. Features an uncleaved signal peptide.; High confidence in function and specificity; carboxy-terminal processing peptidase 1982541 10978484 zobellia_1681 Zobellia galactanivorans carboxy-terminal processing peptidase YP_004736123.1 1980910 D 63186 CDS YP_004736124.1 340617671 10974593 1982564..1982950 1 NC_015844.1 Family membership; glyoxalase superfamily protein 1982950 10974593 zobellia_1682 Zobellia galactanivorans glyoxalase superfamily protein YP_004736124.1 1982564 D 63186 CDS YP_004736125.1 340617672 10974594 complement(1982962..1983756) 1 NC_015844.1 Contains a domain of unknown function (DUF1080) that may adopt a concavalin-like or glucanase-like fold; Prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1983756 10974594 zobellia_1683 Zobellia galactanivorans lipoprotein YP_004736125.1 1982962 R 63186 CDS YP_004736126.1 340617673 10974595 complement(1983797..1984837) 1 NC_015844.1 Contains nine transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 1984837 10974595 zobellia_1684 Zobellia galactanivorans membrane protein YP_004736126.1 1983797 R 63186 CDS YP_004736127.1 340617674 10974596 1985074..1987497 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 95 of the glycoside hydrolases (GH95); Signal peptide cleaved between the residues 34 and 35. Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 1987497 afcA3 10974596 afcA3 Zobellia galactanivorans alpha-L-fucosidase YP_004736127.1 1985074 D 63186 CDS YP_004736128.1 340617675 10977478 1987551..1989680 1 NC_015844.1 Dehydrogenase with a N-terminal domain that adopts a beta-propeller fold and binds the pyrroloquinoline quinone (PQQ) as prosthetic group. Contains also a C-type cytochrome domain with a heme group covalently bound by thioether bonds to two conserved cysteine residues; Belongs to the Quinoprotein alcohol dehydrogenase family; Putative lipoprotein signal peptide cleaved between the residues 21 and 22; Possibly localized in the outer membrane; Specificity unclear; pyrroloquinoline quinone-dependent dehydrogenase 1989680 10977478 zobellia_1686 Zobellia galactanivorans pyrroloquinoline quinone-dependent dehydrogenase YP_004736128.1 1987551 D 63186 CDS YP_004736129.1 340617676 10974597 1989790..1990656 1 NC_015844.1 Fructosamine kinase is responsible for the removal of fructosamines from proteins, by a sugar phosphorylation mechanism; Localized in the cytoplasm; High confidence in function and specificity; fructosamine kinase 1990656 10974597 zobellia_1687 Zobellia galactanivorans fructosamine kinase YP_004736129.1 1989790 D 63186 CDS YP_004736130.1 340617677 10974598 1991008..1991706 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1991706 10974598 zobellia_1688 Zobellia galactanivorans hypothetical protein YP_004736130.1 1991008 D 63186 CDS YP_004736131.1 340617678 10974599 1991706..1993049 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 1993049 10974599 zobellia_1689 Zobellia galactanivorans hypothetical protein YP_004736131.1 1991706 D 63186 CDS YP_004736132.1 340617679 10974600 1993052..1993648 1 NC_015844.1 Protein that contains three repeats of twenty aminoacids The MORN (membrane occupation and recognition nexus) repeats would contribute to the plasma membrane binding, possibly by interacting with phospholipids; Seems localized in the cytoplasm; hypothetical protein 1993648 10974600 zobellia_1690 Zobellia galactanivorans hypothetical protein YP_004736132.1 1993052 D 63186 CDS YP_004736133.1 340617680 10974602 1993978..1994421 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 1994421 10974602 zobellia_1691 Zobellia galactanivorans lipoprotein YP_004736133.1 1993978 D 63186 CDS YP_004736134.1 340617681 10974603 complement(1994552..1995745) 1 NC_015844.1 Dipeptidyl peptidase hydrolyzes gamma-D-Glu-L-(meso)A2pm linkages only in those peptide units that have a free N-terminal L-alanine. It is involved in peptidoglycan metabolism; Belongs to the family C40 of peptidases; Prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; High confidence in function and specificity; dipeptidyl peptidase 1995745 10974603 zobellia_1692 Zobellia galactanivorans dipeptidyl peptidase YP_004736134.1 1994552 R 63186 CDS YP_004736135.1 340617682 10974604 1995829..1997055 1 NC_015844.1 DNA (cytosine-5-)-methyltransferase specifically methylates the C-5 carbon of cytosines in DNA to produce C5-methylcytosine. It uses S-adenosyl-L-methionine as methyl donor. This protein is highly; High confidence in function and specificity; DNA (cytosine-5-)-methyltransferase 1997055 10974604 zobellia_1693 Zobellia galactanivorans DNA (cytosine-5-)-methyltransferase YP_004736135.1 1995829 D 63186 CDS YP_004736136.1 340617683 10974605 1997086..1997700 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1997700 10974605 zobellia_1694 Zobellia galactanivorans hypothetical protein YP_004736136.1 1997086 D 63186 CDS YP_004736137.1 340617684 10974606 1997958..1998332 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 1998332 10974606 zobellia_1695 Zobellia galactanivorans hypothetical protein YP_004736137.1 1997958 D 63186 CDS YP_004736138.1 340617685 10974607 complement(1998380..1998823) 1 NC_015844.1 N-acetyltransferase belonging to the GCN5 family, but its exact specificity is unknown; Localized in the cytoplasm; Specificity unclear; N-acetyltransferase ElaA 1998823 elaA 10974607 elaA Zobellia galactanivorans N-acetyltransferase ElaA YP_004736138.1 1998380 R 63186 CDS YP_004736139.1 340617686 10977777 complement(1998828..1999745) 1 NC_015844.1 This integral membrane protein belongs to a family of proteins that are found to increase tolerance to divalent metal ions such as cadmium, zinc, and cobalt. These proteins are thought to be efflux pumps that remove these ions from cells. Features six transmembrane helices.; Specificity unclear; cation efflux protein 1999745 10977777 zobellia_1697 Zobellia galactanivorans cation efflux protein YP_004736139.1 1998828 R 63186 CDS YP_004736140.1 340617687 10974608 complement(1999898..2000329) 1 NC_015844.1 Ribose 5-phosphate isomerase B catalyses the conversion of D-ribose 5-phosphate to D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; Forms a homodimer; Localized in the cytoplasm; High confidence in function and specificity; ribose-5-phosphate isomerase B 2000329 rpiB 10974608 rpiB Zobellia galactanivorans ribose-5-phosphate isomerase B YP_004736140.1 1999898 R 63186 CDS YP_004736141.1 340617688 10978492 2000994..2003189 1 NC_015844.1 Ribonuclease R is a 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; RNase R degrades RNA with secondary structure having a 3'overhang of at least 7 nucleotides. RNase R and polynucleotide phosphorylase play an important role in the degradation of RNA with extensive secondary structure, (rRNA, tRNA, and certain mRNA) which contains repetitive extragenic palindromic sequences. Contains a C-terminal S1 domain that binds ssRNA. Forms a monomer; Localized in the cytoplasm; High confidence in function and specificity; ribonuclease r 2003189 vacB 10978492 vacB Zobellia galactanivorans ribonuclease r YP_004736141.1 2000994 D 63186 CDS YP_004736142.1 340617689 10978742 2003246..2003926 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2003926 10978742 zobellia_1700 Zobellia galactanivorans hypothetical protein YP_004736142.1 2003246 D 63186 CDS YP_004736143.1 340617690 10974611 2004042..2004710 1 NC_015844.1 This conserved integral membrane protein is likely an amino acid translocator; Contains six transmembrane helices; belongs to the LysE family; Localized in the cytoplasmic membrane; Family membership; LysE-type amino acid translocator 2004710 10974611 zobellia_1701 Zobellia galactanivorans LysE-type amino acid translocator YP_004736143.1 2004042 D 63186 CDS YP_004736144.1 340617691 10974029 complement(2005016..2005378) 1 NC_015844.1 Dihydroneopterin aldolase catalyses the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate; Localized in the cytoplasm; High confidence in function and specificity; dihydroneopterin aldolase 2005378 folB 10974029 folB Zobellia galactanivorans dihydroneopterin aldolase YP_004736144.1 2005016 R 63186 CDS YP_004736145.1 340617692 10977835 complement(2005489..2006442) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; hypothetical protein 2006442 10977835 zobellia_1704 Zobellia galactanivorans hypothetical protein YP_004736145.1 2005489 R 63186 CDS YP_004736146.1 340617694 10974613 complement(2006474..2021098) 1 NC_015844.1 Putatively contains a B_ant_repeat domain (DUF 11) and a Concanavalin A-like lectin/glucanase domain in the N-terminal region; Contains also at least four BNR/Asp-box repeats (bacterial neuraminidase repeat) found in many glycoside hydrolases and in other extracellular proteins of unknown function; Signal peptide cleaved between the residues 23 and 24; Probably localized in the outer membrane; hypothetical protein 2021098 10974613 zobellia_1706 Zobellia galactanivorans hypothetical protein YP_004736146.1 2006474 R 63186 CDS YP_004736147.1 340617693 10974615 2020487..2020732 1 NC_015844.1 Hypothetical protein; hypothetical protein 2020732 10974615 zobellia_1705 Zobellia galactanivorans hypothetical protein YP_004736147.1 2020487 D 63186 CDS YP_004736148.1 340617695 10974614 complement(2021099..2023210) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2023210 10974614 zobellia_1707 Zobellia galactanivorans periplasmic protein YP_004736148.1 2021099 R 63186 CDS YP_004736149.1 340617696 10974616 complement(2023221..2025494) 1 NC_015844.1 Contains a central Ig-like domain (residues 511-592); Signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2025494 10974616 zobellia_1708 Zobellia galactanivorans periplasmic protein YP_004736149.1 2023221 R 63186 CDS YP_004736150.1 340617697 10974617 2025715..2027397 1 NC_015844.1 Glutaminyl-tRNA synthetase is a class Ic synthetase and catalyzes the attachment of glutamine to its cognate transfer RNA molecule. This monomeric enzyme has an architecture; High confidence in function and specificity; glutaminyl-tRNA synthetase 2027397 glnS 10974617 glnS Zobellia galactanivorans glutaminyl-tRNA synthetase YP_004736150.1 2025715 D 63186 CDS YP_004736151.1 340617698 10977919 2027803..2028132 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2028132 10977919 zobellia_1710 Zobellia galactanivorans membrane protein YP_004736151.1 2027803 D 63186 CDS YP_004736152.1 340617699 10974618 2028136..2028486 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2028486 10974618 zobellia_1711 Zobellia galactanivorans membrane protein YP_004736152.1 2028136 D 63186 CDS YP_004736153.1 340617700 10974619 2028483..2028698 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 2028698 10974619 zobellia_1712 Zobellia galactanivorans hypothetical protein YP_004736153.1 2028483 D 63186 CDS YP_004736154.1 340617701 10974620 complement(2028789..2029721) 1 NC_015844.1 The Band 7 protein is an integral membrane phosphoprotein of red blood cells thought to regulate cation conductance. Bacterial homologues are known, but their exact function is uncertain; Contains a N-terminal transmembrane helices; Localized in the cytoplasmic membrane; Family membership; hypothetical protein 2029721 10974620 zobellia_1713 Zobellia galactanivorans hypothetical protein YP_004736154.1 2028789 R 63186 CDS YP_004736155.1 340617702 10974621 complement(2029907..2031415) 1 NC_015844.1 Glutamyl-tRNA synthetase (GluRS) is a monomeric enzyme that catalyzes the attachment of glutamate to its cognate transfer RNA molecule in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Binds 1 zinc ion per subunit; Belongs to the class-I aminoacyl-tRNA synthetase family, subclasse c; Localized in the cytoplasm; High confidence in function and specificity; glutamyl-tRNA synthetase 2031415 gltX 10974621 gltX Zobellia galactanivorans glutamyl-tRNA synthetase YP_004736155.1 2029907 R 63186 CDS YP_004736156.1 340617703 10977933 2031548..2035009 1 NC_015844.1 Contains three transmembrane helices in the N-terminal region; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2035009 10977933 zobellia_1715 Zobellia galactanivorans membrane protein YP_004736156.1 2031548 D 63186 CDS YP_004736157.1 340617704 10974622 2035002..2035421 1 NC_015844.1 Conserved protein belonging to the UPF0054 family; Localized in the cytoplasm; Family membership; hypothetical protein 2035421 10974622 zobellia_1716 Zobellia galactanivorans hypothetical protein YP_004736157.1 2035002 D 63186 CDS YP_004736158.1 340617705 10974623 2035485..2037353 1 NC_015844.1 The protein MnmG (or GidA glucose-inhibited division protein A) is a NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34; Binds the FAD as cofactor; Homodimer that forms a heterotetramer of two MnmE and two MnmG subunits; Belongs to the MnmG family; Localized in the cytoplasm; High confidence in function and specificity; tRNA uridine 5-carboxymethylaminomethyl modification protein MnmG 2037353 mnmG 10974623 mnmG Zobellia galactanivorans tRNA uridine 5-carboxymethylaminomethyl modification protein MnmG YP_004736158.1 2035485 D 63186 CDS YP_004736159.1 340617706 10978162 2037504..2037734 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2037734 10978162 zobellia_1718 Zobellia galactanivorans hypothetical protein YP_004736159.1 2037504 D 63186 CDS YP_004736160.1 340617707 10974624 complement(2037951..2038094) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2038094 10974624 zobellia_1719 Zobellia galactanivorans hypothetical protein YP_004736160.1 2037951 R 63186 CDS YP_004736161.1 340617708 10974625 2038151..2038981 1 NC_015844.1 This protein display a SAM-binding domain and is likely a methyltransferase. S-adenosyl-L-methionine (SAM) is a ubiquitous methyl donor; Localized in the cytoplasm; Specificity unclear; SAM-dependent methyltransferase 2038981 10974625 zobellia_1720 Zobellia galactanivorans SAM-dependent methyltransferase YP_004736161.1 2038151 D 63186 CDS YP_004736162.1 340617709 10974626 2039360..2039869 1 NC_015844.1 Outer membrane protein belonging to the OmpH family. OmpH acts as a channel-forming transmembrane porin. OmpH is a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery; Localized in the outer membrane; Family membership; OmpH family outer membrane protein 2039869 10974626 zobellia_1721 Zobellia galactanivorans OmpH family outer membrane protein YP_004736162.1 2039360 D 63186 CDS YP_004736163.1 340617710 10974627 complement(2039926..2040324) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2040324 10974627 zobellia_1722 Zobellia galactanivorans membrane protein YP_004736163.1 2039926 R 63186 CDS YP_004736164.1 340617711 10974628 complement(2040387..2041538) 1 NC_015844.1 The delta prime subunit of DNA polymerase III is part of the 'clamp' loading complex that assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork; The DNA polymerase III or replicase is responsible for most of the replicative synthesis in bacteria. It also exhibits a 3' to 5' exonuclease proofreading activity; Localized in the cytoplasm; High confidence in function and specificity; DNA polymerase III subunit delta' 2041538 holB 10974628 holB Zobellia galactanivorans DNA polymerase III subunit delta' YP_004736164.1 2040387 R 63186 CDS YP_004736165.1 340617712 10977989 2041681..2042871 1 NC_015844.1 Phosphoglycerate kinase transfers a phosphate group from 1,3-biphosphoglycerate to ADP, forming ATP and 3-Phosphoglycerate in the seventh step of the glycolysis Embden-Meyerhof pathway). PgkA exists as a monomer containing two nearly equal-sized domains that correspond to the N- and C-termini of the protein. 3-phosphoglycerate binds to the N-terminal, while the nucleotide substrates, MgATP or MgADP, bind to the C-terminal domain of the enzyme; Localized in the cytoplasm; High confidence in function and specificity; phosphoglycerate kinase 2042871 pgkA 10977989 pgkA Zobellia galactanivorans phosphoglycerate kinase YP_004736165.1 2041681 D 63186 CDS YP_004736166.1 340617713 10978337 2043026..2044669 1 NC_015844.1 Lytic murein transglycosylase catalyzes the cleavage of the beta-1,4-glycosidic bond between N- acetylmuramic acid and N-acetylglucosamine residues, thereby conserving the energy in a newly synthesized 1,6- anhydrobond in the muramic acid residue. May play a role in recycling of muropeptides during cell elongation and/or cell division; Contains a N-terminal catalytic module belonging to the family 23 of the glycoside hydrolases (GH23) and two C-terminal LysM domains, predicted to bind peptidoglycans and belonging to the family 50 of the carbohydrate binding modules (CBM50); Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasm; Specificity unclear; lytic murein transglycosylase 2044669 10978337 zobellia_1725 Zobellia galactanivorans lytic murein transglycosylase YP_004736166.1 2043026 D 63186 CDS YP_004736167.1 340617714 10974629 2044683..2045678 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 17 and 18; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 2045678 10974629 zobellia_1726 Zobellia galactanivorans membrane protein YP_004736167.1 2044683 D 63186 CDS YP_004736168.1 340617715 10974630 complement(2046085..2048619) 1 NC_015844.1 This protein has a modular architecture with a N-terminal domain of unknown function, a central beta-propeller domain, encompassing three WD40 repeats, and a C-terminal OmpA domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan. Contains a signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Function unclear; OmpA-like outer membrane protein 2048619 10974630 zobellia_1727 Zobellia galactanivorans OmpA-like outer membrane protein YP_004736168.1 2046085 R 63186 CDS YP_004736169.1 340617716 10974631 complement(2048980..2049162) 1 NC_015844.1 The TatA protein is required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif S/T-R-R-X-F-L-K. TatA seems to form the protein-conducting channel of the TAT system; Contains one N-terminal transmembrane segment; Localized in the cytoplasmic membrane; High confidence in function and specificity; Sec-independent protein translocase TatA 2049162 tatA 10974631 tatA Zobellia galactanivorans Sec-independent protein translocase TatA YP_004736169.1 2048980 R 63186 CDS YP_004736170.1 340617717 10978639 2049358..2050224 1 NC_015844.1 Peptidase family M23 mainly contains endopeptidases that lyze bacterial cell wall peptidoglycans. One catalytic zinc ion is bound per peptidase molecule. The cation ligands occur in the conserved motifs HXXXD and HXH. The first histidine of the second motif is also involved in the catalysis. Contains a transmembrane helix in N-terminus. Localized in the cytoplasmic membrane; Specificity unclear; metallopeptidase 2050224 10978639 zobellia_1729 Zobellia galactanivorans metallopeptidase YP_004736170.1 2049358 D 63186 CDS YP_004736171.1 340617718 10974632 2050300..2051796 1 NC_015844.1 Conserved hypothetical protein distantly related to the Auxin-responsive GH3-like proteins; Localized in the cytoplasm; hypothetical protein 2051796 10974632 zobellia_1730 Zobellia galactanivorans hypothetical protein YP_004736171.1 2050300 D 63186 CDS YP_004736172.1 340617719 10974633 2051771..2051866 1 NC_015844.1 Hypothetical protein; hypothetical protein 2051866 10974633 zobellia_1731 Zobellia galactanivorans hypothetical protein YP_004736172.1 2051771 D 63186 CDS YP_004736173.1 340617720 10974634 2051952..2053637 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2053637 10974634 zobellia_1732 Zobellia galactanivorans hypothetical protein YP_004736173.1 2051952 D 63186 CDS YP_004736174.1 340617721 10974635 2053641..2054648 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2054648 10974635 zobellia_1733 Zobellia galactanivorans membrane protein YP_004736174.1 2053641 D 63186 CDS YP_004736175.1 340617722 10974636 2054659..2055681 1 NC_015844.1 dTDP-glucose 4,6-dehydratase converts the dTDP-glucose to dTDP-4-dehydro-6-deoxy-D-glucose. This enzyme is involved in the nucleotide sugar metabolism and in the lipopolysaccharide biosynthesis; Belongs to the NAD dependent epimerase/dehydratase family, Rossmann fold Superfamily; Localized in the cytoplasm; High confidence in function and specificity; dTDP-glucose 4,6-dehydratase 2055681 rmlB 10974636 rmlB Zobellia galactanivorans dTDP-glucose 4,6-dehydratase YP_004736175.1 2054659 D 63186 CDS YP_004736176.1 340617723 10978475 2055685..2056539 1 NC_015844.1 Glucose-1-phosphate thymidylyltransferase transferts the dTDP on glucose molecule from dTTP and alpha-D-glucose-1-phosphate. This enzyme is involved in the nucleotide sugar metabolism and in the lipopolysaccharide biosynthesis. RmlA forms a homotetramer and binds one Mg2+ per subunit; Belongs to the nucleotidyl transferase family; Localized in the cytoplasm; High confidence in function and specificity; glucose-1-phosphate thymidylyltransferase 2056539 rmlA 10978475 rmlA Zobellia galactanivorans glucose-1-phosphate thymidylyltransferase YP_004736176.1 2055685 D 63186 CDS YP_004736177.1 340617724 10978474 2056558..2057103 1 NC_015844.1 dTDP-4-dehydrorhamnose 3,5-epimerase converts the dTDP-4-dehydro-6-deoxy-D-glucose to dTDP-4-dehydro-6-deoxy-L-mannose. RmlC is involved in the nucleotide sugar metabolism and in the lipopolysaccharide biosynthesis; forms a homodimer; Belongs to the Cupin fold clan; Localized in the cytoplasm; High confidence in function and specificity; dTDP-4-dehydrorhamnose 3,5-epimerase 2057103 rmlC 10978474 rmlC Zobellia galactanivorans dTDP-4-dehydrorhamnose 3,5-epimerase YP_004736177.1 2056558 D 63186 CDS YP_004736178.1 340617725 10978476 2057100..2057876 1 NC_015844.1 dTDP-4-dehydrorhamnose reductase converts the dTDP-6-deoxy-L-mannose to dTDP-4-dehydro-6-deoxy-L-mannose. RmlD is involved in the nucleotide sugar metabolism and in the lipopolysaccharide biosynthesis; Belongs to the RmlD substrate binding domain family, Rossmann fold Superfamily; Localized in the cytoplasm; High confidence in function and specificity; dTDP-4-dehydrorhamnose reductase 2057876 rmlD 10978476 rmlD Zobellia galactanivorans dTDP-4-dehydrorhamnose reductase YP_004736178.1 2057100 D 63186 CDS YP_004736179.1 340617726 10978477 2057895..2058476 1 NC_015844.1 dTDP-D-Fucp3N acetylase catalyzes the transfer of an acetyl group from acetyl-CoA to dTDP-D-Fucp3N to form dTDP-D-Fucp3NAc. FdtC is involved in the biosynthesis of lipopolysaccharides; Belongs to the o-acetyltransferase family; Contains five tandem repeats of a [LIV]-G-X(4) hexapeptide, which folds as a left-handed parallel beta helix; Localized in the cytoplasm; High confidence in function and specificity; dTDP-D-Fucp3N acetylase 2058476 fdtC 10978477 fdtC Zobellia galactanivorans dTDP-D-Fucp3N acetylase YP_004736179.1 2057895 D 63186 CDS YP_004736180.1 340617727 10977822 2058497..2059594 1 NC_015844.1 The dTDP-6-deoxy-D-xylo-hex-3-ulose aminase aminates specifically dTDP-6-deoxy-D-xylo-hex-3-ulose to form dTP-D-Fucp3N. FdtB, involved in the biosynthesis of lipopolysaccharides, requires pyridoxal-phosphate and L-glutamate as cofactors; Belongs to the DegT/DnrJ/EryC1/StrS aminotransferase family, PLP dependent aminotransferase superfamily; Localized in the cytoplasm; High confidence in function and specificity; dTDP-6-deoxy-D-xylo-hex-3-ulose aminase 2059594 fdtB 10977822 fdtB Zobellia galactanivorans dTDP-6-deoxy-D-xylo-hex-3-ulose aminase YP_004736180.1 2058497 D 63186 CDS YP_004736181.1 340617728 10977821 2059591..2060529 1 NC_015844.1 WbpB is a NAD(P)-dependent oxidoreductase involved in lipopolysaccharide biosynthesis; Belongs to the GFO/IDH/MOCA family; Adopts a Rossmann fold; Localized in the cytoplasm; Specificity unclear; lipopolysaccharide biosynthesis protein WbpB 2060529 wbpB 10977821 wbpB Zobellia galactanivorans lipopolysaccharide biosynthesis protein WbpB YP_004736181.1 2059591 D 63186 CDS YP_004736182.1 340617729 10978751 2060542..2061591 1 NC_015844.1 UDP-N-acetylglucosamine 2-epimerase converts the UDP-N-acetyl-D-glucosamine to UDP-N-acetyl-D-mannosamine. WecB is involved in amino sugar metabolism and in the lipopolysaccharide biosynthesis; Belongs to the UDP-Glycosyltransferase/glycogen phosphorylase superfamily; Localized in the cytoplasm; High confidence in function and specificity; UDP-N-acetylglucosamine 2-epimerase 2061591 wecB 10978751 wecB Zobellia galactanivorans UDP-N-acetylglucosamine 2-epimerase YP_004736182.1 2060542 D 63186 CDS YP_004736183.1 340617730 10978754 2061600..2062901 1 NC_015844.1 WzxA translocates undecaprenylpyrophosphate-bound O-antigen subunits from the cytoplasm to the periplasm. Wzx is an integral membrane protein involved in lipopolysaccharide biosynthesis; Localized in the cytoplasmic membrane; High confidence in function and specificity; O-antigen translocase 2062901 wzxA 10978754 wzxA Zobellia galactanivorans O-antigen translocase YP_004736183.1 2061600 D 63186 CDS YP_004736184.1 340617731 10978757 2062891..2064462 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2064462 10978757 zobellia_1743 Zobellia galactanivorans hypothetical protein YP_004736184.1 2062891 D 63186 CDS YP_004736185.1 340617732 10974638 2064462..2065019 1 NC_015844.1 CapJ is involved in the capsular polysaccharide biosynthesis. Its features three tandem repeats of a [LIV]-G-X(4) hexapeptide, which folds as a left-handed parallel beta helix; Belongs to the o-acetyltransferase family; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Specificity unclear; capsular polysaccharide synthesis O-acetyltransferase CapJ 2065019 capJ 10974638 capJ Zobellia galactanivorans capsular polysaccharide synthesis O-acetyltransferase CapJ YP_004736185.1 2064462 D 63186 CDS YP_004736186.1 340617733 10977620 2065103..2066233 1 NC_015844.1 The protein WbmB was first found in an O antigen biosynthesis operon from the genus Bordetella. Its exact function is still unknown; Localized in the cytoplasm; Function unclear; O antigen biosynthesis protein WbmB 2066233 wbmB 10977620 wbmB Zobellia galactanivorans O antigen biosynthesis protein WbmB YP_004736186.1 2065103 D 63186 CDS YP_004736187.1 340617734 10978750 2066300..2067538 1 NC_015844.1 Contains nine transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2067538 10978750 zobellia_1746 Zobellia galactanivorans hypothetical protein YP_004736187.1 2066300 D 63186 CDS YP_004736188.1 340617735 10974639 2067535..2068758 1 NC_015844.1 The protein WbeiA was first found in an O antigen biosynthesis gene cluster from Edwardsiella ictaluri. Its exact function is still unknown; Contains eleven transmembrane helices; Localized in the cytoplasmic membrane; Function unclear; O antigen biosynthesis protein WbeiA 2068758 wbeiA 10974639 wbeiA Zobellia galactanivorans O antigen biosynthesis protein WbeiA YP_004736188.1 2067535 D 63186 CDS YP_004736189.1 340617736 10978748 2068745..2069542 1 NC_015844.1 Glycosyltransferase putatively involved in the Lipopolysaccharide core or in the exopolysaccharide biosynthesis; Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; Contains a C-terminal transmembrane segment; Belongs to the family 2 of glycosyl transferase (GT2), WaaE/kdtX subfamily; Localized in the cytoplasmic membrane; Family membership; glycosyltransferase 2069542 10978748 zobellia_1748 Zobellia galactanivorans glycosyltransferase YP_004736189.1 2068745 D 63186 CDS YP_004736190.1 340617737 10974640 2069539..2070783 1 NC_015844.1 The protein WbgV was first found in an O antigen biosynthesis gene cluster in Enterobacteriaceae. Its exact function is still unknown; Localized in the cytoplasm; Function unclear; O antigen biosynthesis protein WbgV 2070783 wbgV 10974640 wbgV Zobellia galactanivorans O antigen biosynthesis protein WbgV YP_004736190.1 2069539 D 63186 CDS YP_004736191.1 340617738 10978749 2070797..2071537 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme is closely related to TuaG protein which is involved in the biosynthesis of theichuronic acid, a cell wall anionic polysaccharide in Firmicutes; Belongs to the family 2 of the glycosyltransferases (GT2); Localized in the cytoplasm; Specificity unclear; glycosyltransferase 2071537 10978749 zobellia_1750 Zobellia galactanivorans glycosyltransferase YP_004736191.1 2070797 D 63186 CDS YP_004736192.1 340617739 10974642 2071555..2072922 1 NC_015844.1 Protein involved in exopolysaccharide biosynthesis. Its exact function is unknown; Contains five transmembrane helices Localized in the cytoplasmic membrane; Function unclear; exopolysaccharide production protein 2072922 10974642 zobellia_1751 Zobellia galactanivorans exopolysaccharide production protein YP_004736192.1 2071555 D 63186 CDS YP_004736193.1 340617740 10974643 2073042..2074313 1 NC_015844.1 Phosphoribosylamine glycine ligase (also known as phosphoribosylglycinamide synthetase) catalyses the second step in the de novo biosynthesis of purine: the ATP-dependent addition of 5-phosphoribosylamine to glycine to form 5'phosphoribosylglycinamide. Localized in the cytoplasm.; High confidence in function and specificity; phosphoribosylamine glycine ligase 2074313 purD 10974643 purD Zobellia galactanivorans phosphoribosylamine glycine ligase YP_004736193.1 2073042 D 63186 CDS YP_004736194.1 340617741 10978406 complement(2074362..2074583) 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2074583 10978406 zobellia_1753 Zobellia galactanivorans membrane protein YP_004736194.1 2074362 R 63186 CDS YP_004736195.1 340617742 10974644 2074775..2075713 1 NC_015844.1 Contains eight transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2075713 10974644 zobellia_1754 Zobellia galactanivorans membrane protein YP_004736195.1 2074775 D 63186 CDS YP_004736196.1 340617743 10974645 2075749..2076351 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2076351 10974645 zobellia_1755 Zobellia galactanivorans hypothetical protein YP_004736196.1 2075749 D 63186 CDS YP_004736197.1 340617744 10974646 2076386..2077387 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme is a glycosyltransferase involved in the biosynthesis of the lipopolysaccharide core; Belongs to the family 9 of the glycosyltransferase (GT9); Localized in the cytoplasm; Specificity unclear; lipopolysaccharide core biosynthesis glycosyltransferase 2077387 10974646 zobellia_1756 Zobellia galactanivorans lipopolysaccharide core biosynthesis glycosyltransferase YP_004736197.1 2076386 D 63186 CDS YP_004736198.1 340617745 10974647 complement(2077394..2078050) 1 NC_015844.1 Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership; TetR family transcriptional regulator 2078050 10974647 zobellia_1757 Zobellia galactanivorans TetR family transcriptional regulator YP_004736198.1 2077394 R 63186 CDS YP_004736199.1 340617746 10974648 2078379..2079089 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2079089 10974648 zobellia_1758 Zobellia galactanivorans hypothetical protein YP_004736199.1 2078379 D 63186 CDS YP_004736200.1 340617747 10974649 2079184..2082402 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (24-82) and the Plug module (113-241) acting as a channel gate; The signal peptide is cleaved between the residues 22 and 23; Family membership; TonB-dependent Receptor 2082402 10974649 zobellia_1759 Zobellia galactanivorans TonB-dependent Receptor YP_004736200.1 2079184 D 63186 CDS YP_004736201.1 340617748 10974650 2082415..2083884 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 27 and 28; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 2083884 10974650 zobellia_1760 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736201.1 2082415 D 63186 CDS YP_004736202.1 340617749 10974652 2083964..2085187 1 NC_015844.1 Periplasmic lipoprotein of unknown function that is a part of an ABC transporter system; Belongs to the periplasmic substrate-binding ABC transporter superfamily; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasm space putatively anchored in the cytoplasmic membrane; Specificity unclear; ABC transporter periplasmic protein 2085187 10974652 zobellia_1761 Zobellia galactanivorans ABC transporter periplasmic protein YP_004736202.1 2083964 D 63186 CDS YP_004736203.1 340617750 10974653 2085177..2086031 1 NC_015844.1 ABC (ATP-binding cassette) transporter, membrane domain; Proteins responsible for import of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Specificity unclear; ABC transporter permease 2086031 10974653 zobellia_1762 Zobellia galactanivorans ABC transporter permease YP_004736203.1 2085177 D 63186 CDS YP_004736204.1 340617751 10974654 2086021..2086794 1 NC_015844.1 ABC (ATP-binding cassette) transporter, membrane domain; Proteins responsible for import of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Specificity unclear; ABC transporter permease 2086794 10974654 zobellia_1763 Zobellia galactanivorans ABC transporter permease YP_004736204.1 2086021 D 63186 CDS YP_004736205.1 340617752 10974655 2086794..2087513 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes of the permease component (ABC membrane); Localized in the cytoplasmic membrane as a peripheral membrane protein; Family membership; ABC transporter ATPase 2087513 10974655 zobellia_1764 Zobellia galactanivorans ABC transporter ATPase YP_004736205.1 2086794 D 63186 CDS YP_004736206.1 340617753 10974656 2087563..2088483 1 NC_015844.1 Ribonucleoside hydrolase catalyzes the hydrolysis of purine and pyrimidine nucleosides into ribose and the associated base; Belongs to the IUNH family; Localized in the cytoplasm; Specificity unclear; ribonucleoside hydrolase 2088483 10974656 zobellia_1765 Zobellia galactanivorans ribonucleoside hydrolase YP_004736206.1 2087563 D 63186 CDS YP_004736207.1 340617754 10974657 2088518..2089303 1 NC_015844.1 Conserved protein belonging to the Patatin-like phospholipase family; Localized in the cytoplasm; Family membership; Patatin-like phospholipase 2089303 10974657 zobellia_1766 Zobellia galactanivorans Patatin-like phospholipase YP_004736207.1 2088518 D 63186 CDS YP_004736208.1 340617755 10974658 complement(2089345..2090394) 1 NC_015844.1 The protein PaaE is involved in the phenylacetic acid aerobic catabolism. It is likely part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation. It is activated by cAMP receptor protein (CRP) and the integration host factor (IHF). Contains a N-terminal FAD-binding domain, a central feredoxin-like NAD-binding domain and a C-terminal 2Fe-2S iron-sulfur cluster binding domain; Localized in the cytoplasm.; High confidence in function and specificity; phenylacetic acid degradation NADH oxidoreductase 2090394 paaE 10974658 paaE Zobellia galactanivorans phenylacetic acid degradation NADH oxidoreductase YP_004736208.1 2089345 R 63186 CDS YP_004736209.1 340617756 10978291 2090504..2090860 1 NC_015844.1 Transcriptional regulator belonging to the PadR family. Features a helix-turn-helix DNA binding motif. Localized in the cytoplasm.; Specificity unclear; PadR-type transcriptional regulator 2090860 10978291 zobellia_1768 Zobellia galactanivorans PadR-type transcriptional regulator YP_004736209.1 2090504 D 63186 CDS YP_004736210.1 340617757 10974659 2090934..2091644 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2091644 10974659 zobellia_1769 Zobellia galactanivorans membrane protein YP_004736210.1 2090934 D 63186 CDS YP_004736211.1 340617758 10974660 2091706..2093175 1 NC_015844.1 Contains twelve transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2093175 10974660 zobellia_1770 Zobellia galactanivorans membrane protein YP_004736211.1 2091706 D 63186 CDS YP_004736212.1 340617759 10974662 2093230..2093958 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase) encoded by a different gene of those that encode for the ABC transporter permease component (ABC membrane); Family membership; ABC transporter ATPase 2093958 10974662 zobellia_1771 Zobellia galactanivorans ABC transporter ATPase YP_004736212.1 2093230 D 63186 CDS YP_004736213.1 340617760 10974663 complement(2094016..2094297) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2094297 10974663 zobellia_1772 Zobellia galactanivorans hypothetical protein YP_004736213.1 2094016 R 63186 CDS YP_004736214.1 340617761 10974664 2094476..2097028 1 NC_015844.1 The SprE protein could be involved in the gliding motility; Contains four tetratrico peptide repeats (TPRs). TPRs mediate proteinprotein interactions. TPR adopts a helixturnhelix arrangement, with adjacent TPR motifs packing in a parallel fashion, resulting in a spiral of repeating anti-parallel alpha-helices. SprE contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Function unclear; gliding motility membrane lipoprotein SprE 2097028 sprE 10974664 sprE Zobellia galactanivorans gliding motility membrane lipoprotein SprE YP_004736214.1 2094476 D 63186 CDS YP_004736215.1 340617762 10978608 2097032..2097472 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF583 family; Localized in the cytoplasm; hypothetical protein 2097472 10978608 zobellia_1774 Zobellia galactanivorans hypothetical protein YP_004736215.1 2097032 D 63186 CDS YP_004736216.1 340617763 10974665 2097450..2097674 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2097674 10974665 zobellia_1775 Zobellia galactanivorans membrane protein YP_004736216.1 2097450 D 63186 CDS YP_004736217.1 340617764 10974666 2097677..2098063 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2098063 10974666 zobellia_1776 Zobellia galactanivorans membrane protein YP_004736217.1 2097677 D 63186 CDS YP_004736218.1 340617765 10974667 2098177..2099337 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). The A subunit is a key membrane component of the proton channel, and may play a direct role in the translocation of protons across the membrane. Catalysis in the F1 complex depends upon the rotation of the central stalk and F0 c-ring, which in turn is driven by the flux of protons through the membrane via the interface between the F0 c-ring and subunit A. The peripheral stalk links subunit A to the external surface of the F1 domain, and is thought to act as a stator to counter the tendency of subunit A and the F1 alpha-beta catalytic portion to rotate with the central rotary element.; High confidence in function and specificity; ATP synthase, F0 sector subunit A 2099337 atpB1 10974667 atpB1 Zobellia galactanivorans ATP synthase, F0 sector subunit A YP_004736218.1 2098177 D 63186 CDS YP_004736219.1 340617766 10977569 2099376..2099564 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). Ten C subunits form an oligomeric ring that makes up the F0 rotor. The flux of protons through the ATPase channel drives the rotation of the C subunit ring, which in turn is coupled to the rotation of the F1 complex gamma subunit rotor due to the permanent binding between the gamma and epsilon subunits of F1 and the C subunit ring of F0. The sequential protonation and deprotonation of Asp61 of subunit C is coupled to the stepwise movement of the rotor.; High confidence in function and specificity; ATP synthase, F0 sector subunit C 2099564 atpE1 10977569 atpE1 Zobellia galactanivorans ATP synthase, F0 sector subunit C YP_004736219.1 2099376 D 63186 CDS YP_004736220.1 340617767 10977575 2099654..2100154 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). The B subunits are part of the peripheral stalk that links the F1 and F0 complexes together, and which acts as a stator to prevent certain subunits from rotating with the central rotary element.; High confidence in function and specificity; ATP synthase, F0 sector subunit B 2100154 atpF1 10977575 atpF1 Zobellia galactanivorans ATP synthase, F0 sector subunit B YP_004736220.1 2099654 D 63186 CDS YP_004736221.1 340617768 10977577 2100221..2100760 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). The delta subunit appears to be part of the peripheral stalk that holds the F1 complex alpha-beta catalytic core stationary against the torque of the rotating central stalk, and links subunit A of the F0 complex with the F1 complex.; High confidence in function and specificity; ATP synthase, F1 sector subunit delta 2100760 atpH 10977577 atpH Zobellia galactanivorans ATP synthase, F1 sector subunit delta YP_004736221.1 2100221 D 63186 CDS YP_004736222.1 340617769 10977581 2100816..2102396 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). There are three copies each of the alpha and beta subunits that form the catalytic core of the F1 complex, while the remaining F1 subunits (gamma, delta, epsilon) form part of the stalks. There is a substrate-binding site on each of the alpha and beta subunits, those on the beta subunits being catalytic, while those on the alpha subunits are regulatory. The alpha and beta subunits form a cylinder that is attached to the central stalk. The alpha/beta subunits undergo a sequence of conformational changes leading to the formation of ATP from ADP, which are induced by the rotation of the gamma subunit, itself is driven by the movement of protons through the F0 complex C subunit.; High confidence in function and specificity; ATP synthase, F1 sector subunit alpha 2102396 atpA1 10977581 atpA1 Zobellia galactanivorans ATP synthase, F1 sector subunit alpha YP_004736222.1 2100816 D 63186 CDS YP_004736223.1 340617770 10977567 2102479..2103339 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). In the F1 complex, the central gamma subunit forms the rotor inside the cylinder made of the alpha beta subunits, while in the F0 complex, the ring-shaped C subunits forms the rotor. The two rotors rotate in opposite directions, but the F0 rotor is usually stronger, using the force from the proton gradient to push the F1 rotor in reverse in order to drive ATP synthesis.; High confidence in function and specificity; ATP synthase, F1 sector subunit gamma 2103339 atpG1 10977567 atpG1 Zobellia galactanivorans ATP synthase, F1 sector subunit gamma YP_004736223.1 2102479 D 63186 CDS YP_004736224.1 340617771 10977579 complement(2103504..2103740) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2103740 10977579 zobellia_1783 Zobellia galactanivorans hypothetical protein YP_004736224.1 2103504 R 63186 CDS YP_004736225.1 340617772 10974669 2103871..2105181 1 NC_015844.1 Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Contains 12 transmembrane segments; Belongs to the multi antimicrobial extrusion (MATE) family, MdtK subfamily; Localized in the cytoplasmic membrane; Specificity unclear; multidrug resistance protein 2105181 mdtK 10974669 mdtK Zobellia galactanivorans multidrug resistance protein YP_004736225.1 2103871 D 63186 CDS YP_004736226.1 340617773 10978139 2105254..2105688 1 NC_015844.1 Deoxyuridine 5'-triphosphate nucleotidohydrolase is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. This enzyme forms a homotrimer. Localized in the cytoplasm.; High confidence in function and specificity; deoxyuridine 5'-triphosphate nucleotidohydrolase 2105688 dut 10978139 dut Zobellia galactanivorans deoxyuridine 5'-triphosphate nucleotidohydrolase YP_004736226.1 2105254 D 63186 CDS YP_004736227.1 340617774 10977772 2105724..2106665 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2106665 10977772 zobellia_1786 Zobellia galactanivorans periplasmic protein YP_004736227.1 2105724 D 63186 CDS YP_004736228.1 340617775 10974670 2106681..2107475 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 22 and 23; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 2107475 10974670 zobellia_1787 Zobellia galactanivorans membrane protein YP_004736228.1 2106681 D 63186 CDS YP_004736229.1 340617776 10974671 2107465..2108694 1 NC_015844.1 This protein displays significant similarity with the metallopeptidases from the family M23, but the ligands of the catalytic zinc are missing (motifs HXXXD and HXH). Peptidase family M23 mainly contains endopeptidases that lyze bacterial cell wall peptidoglycans; Contains a signal peptide cleaved between the residues 26 and 27; Localized in the periplasm; Function unclear; family M23 non-peptidase protein 2108694 10974671 zobellia_1788 Zobellia galactanivorans family M23 non-peptidase protein YP_004736229.1 2107465 D 63186 CDS YP_004736230.1 340617777 10974672 2108702..2109544 1 NC_015844.1 Oxydoreductase NADPH dependent; Belongs to the aldo/keto reductase 1 family; Localized in the cytoplasm; Family membership; aldo/keto reductase 2109544 10974672 zobellia_1789 Zobellia galactanivorans aldo/keto reductase YP_004736230.1 2108702 D 63186 CDS YP_004736231.1 340617778 10974673 complement(2109552..2110064) 1 NC_015844.1 Acyl-CoA thioesterase hydrolyzes fatty acyl-CoA substrates releasing acyl-Coa and fatty acids; Localized in the cytoplasm; Specificity unclear; acyl-CoA thioesterase 2110064 10974673 zobellia_1790 Zobellia galactanivorans acyl-CoA thioesterase YP_004736231.1 2109552 R 63186 CDS YP_004736232.1 340617779 10974675 complement(2110193..2111152) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2111152 10974675 zobellia_1791 Zobellia galactanivorans hypothetical protein YP_004736232.1 2110193 R 63186 CDS YP_004736233.1 340617780 10974676 2111258..2112361 1 NC_015844.1 The protein Smf (or DprA) would be a new member of the recombination-mediator protein family, dedicated to natural bacterial transformation; Localized in the cytoplasm; High confidence in function and specificity; DNA processing protein Smf 2112361 dprA 10974676 dprA Zobellia galactanivorans DNA processing protein Smf YP_004736233.1 2111258 D 63186 CDS YP_004736234.1 340617781 10977761 complement(2112544..2113512) 1 NC_015844.1 Tryptophanyl-tRNA synthetase catalyzes the attachment of tryptophan to its cognate transfer RNA molecule in a highly specific two-step reaction. TrpS forms a homodimer and adopts a characteristic Rossman fold; Belongs to the class I of the tryptophanyl-tRNA synthetase, subclass b; Localized in the cytoplasm; High confidence in function and specificity; tryptophanyl-tRNA synthetase 2113512 trpS 10977761 trpS Zobellia galactanivorans tryptophanyl-tRNA synthetase YP_004736234.1 2112544 R 63186 CDS YP_004736235.1 340617782 10978700 2113585..2114325 1 NC_015844.1 Acyltransferase of unkown specificity; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Specificity unclear; acyltransferase 2114325 10978700 zobellia_1794 Zobellia galactanivorans acyltransferase YP_004736235.1 2113585 D 63186 CDS YP_004736236.1 340617783 10974677 complement(2114359..2115279) 1 NC_015844.1 Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2115279 10974677 zobellia_1795 Zobellia galactanivorans membrane protein YP_004736236.1 2114359 R 63186 CDS YP_004736237.1 340617784 10974678 complement(2115355..2116239) 1 NC_015844.1 Transcriptional regulator belonging to the LysR family. Features a N-terminal helix-turn-helix DNA binding domain and a C-terminal LysR-like substrate binding domain. Localized in the cytoplasm.; Specificity unclear; LysR family transcriptional regulator 2116239 10974678 zobellia_1796 Zobellia galactanivorans LysR family transcriptional regulator YP_004736237.1 2115355 R 63186 CDS YP_004736238.1 340617785 10974679 complement(2116310..2117890) 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2117890 10974679 zobellia_1797 Zobellia galactanivorans membrane protein YP_004736238.1 2116310 R 63186 CDS YP_004736239.1 340617787 10974680 complement(2117946..2118518) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 2118518 10974680 zobellia_1799 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004736239.1 2117946 R 63186 CDS YP_004736240.1 340617786 10974682 2118495..2118614 1 NC_015844.1 Hypothetical protein; hypothetical protein 2118614 10974682 zobellia_1798 Zobellia galactanivorans hypothetical protein YP_004736240.1 2118495 D 63186 CDS YP_004736241.1 340617788 10974681 complement(2118621..2119055) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 2119055 10974681 zobellia_1800 Zobellia galactanivorans lipoprotein YP_004736241.1 2118621 R 63186 CDS YP_004736242.1 340617789 10974685 complement(2119209..2120216) 1 NC_015844.1 Recombinase A is a multifunctional enzyme involved in homologous recombination, natural transformation, DNA repair and induction of the SOS response. It hydrolyzes the ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. RecA also acts as a protease cofactor that promotes autodigestion of the LexA product and phage repressors. The proteolytic inactivation of the LexA repressor by an activated form of RecA may cause a derepression of the 20 or so genes involved in the SOS response; Localized in the cytoplasm; High confidence in function and specificity; Recombinase A 2120216 recA 10974685 recA Zobellia galactanivorans Recombinase A YP_004736242.1 2119209 R 63186 CDS YP_004736243.1 340617790 10978439 complement(2120238..2120444) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2120444 10978439 zobellia_1802 Zobellia galactanivorans hypothetical protein YP_004736243.1 2120238 R 63186 CDS YP_004736244.1 340617791 10974686 2120743..2121774 1 NC_015844.1 Hypothetical sulfurtransferase that contains one rhodanese domain, Belongs to the UPF0176 family; localized in the cytoplasm; hypothetical protein 2121774 10974686 zobellia_1803 Zobellia galactanivorans hypothetical protein YP_004736244.1 2120743 D 63186 CDS YP_004736245.1 340617792 10974687 complement(2121784..2123040) 1 NC_015844.1 The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients; Contains 10 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; major facilitator family transporter 2123040 10974687 zobellia_1804 Zobellia galactanivorans major facilitator family transporter YP_004736245.1 2121784 R 63186 CDS YP_004736246.1 340617793 10974688 2123129..2124370 1 NC_015844.1 Protein highly Its role in Z. galactanivorans is unknown; Localized in the cytoplasm; hypothetical protein 2124370 10974688 zobellia_1805 Zobellia galactanivorans hypothetical protein YP_004736246.1 2123129 D 63186 CDS YP_004736247.1 340617794 10974689 2124363..2124848 1 NC_015844.1 Lipoprotein involved in the gliding motility; Signal peptide cleaved between the residues 16 and 17; Probably localized in the outer membrane; Function unclear; gliding motility membrane lipoprotein 2124848 gldH 10974689 gldH Zobellia galactanivorans gliding motility membrane lipoprotein YP_004736247.1 2124363 D 63186 CDS YP_004736248.1 340617795 10977905 2124852..2127203 1 NC_015844.1 Penicillin-binding protein 1A is a class A PBP involved in the synthesis of cross-linked peptidoglycan from the lipid II intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). The N-terminal domain belongs to the family 51 of the glycosyltransferases. Features an uncleaved signal peptide. Localized in the periplasm, anchored to the cytoplasmic membrane.; High confidence in function and specificity; penicillin-binding protein 1A, family GT51 2127203 pbp1A 10977905 pbp1A Zobellia galactanivorans penicillin-binding protein 1A, family GT51 YP_004736248.1 2124852 D 63186 CDS YP_004736249.1 340617796 10978305 2127320..2128018 1 NC_015844.1 3-Oxoacid CoA-transferase catalyzes the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA. It is an homodimer of a subunit A and a subunit B. ScoA is the subunit A. The transfer of CoA from one substrate to another occurs via a ping pong mechanism which involves the formation of thioester bond between CoA and a conserved glutamate residue at the active site of the enzyme. Localized in the cytoplasm.; High confidence in function and specificity; 3-oxoacid CoA-transferase subunit A 2128018 scoA 10978305 scoA Zobellia galactanivorans 3-oxoacid CoA-transferase subunit A YP_004736249.1 2127320 D 63186 CDS YP_004736250.1 340617797 10978565 2128141..2128794 1 NC_015844.1 3-Oxoacid CoA-transferase catalyzes the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA. It is an homodimer of a subunit A and a subunit B. ScoB is the subunit B. The transfer of CoA from one substrate to another occurs via a ping pong mechanism which involves the formation of thioester bond between CoA and a conserved glutamate residue at the active site of the enzyme. Localized in the cytoplasm.; High confidence in function and specificity; 3-oxoacid CoA-transferase subunit B 2128794 scoB 10978565 scoB Zobellia galactanivorans 3-oxoacid CoA-transferase subunit B YP_004736250.1 2128141 D 63186 CDS YP_004736251.1 340617798 10978566 2128964..2129065 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 2129065 10978566 zobellia_1810 Zobellia galactanivorans hypothetical protein YP_004736251.1 2128964 D 63186 CDS YP_004736252.1 340617799 10974690 complement(2129157..2130314) 1 NC_015844.1 Aminotransferases use the Pyridoxal phosphate as cofactor bound by covalent linkage to a lysine residue; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; Specificity unclear; aminotransferase 2130314 10974690 zobellia_1811 Zobellia galactanivorans aminotransferase YP_004736252.1 2129157 R 63186 CDS YP_004736253.1 340617800 10974691 2130352..2131404 1 NC_015844.1 Contains two transmembrane segments; Protein probably localized in the cytoplasmic membrane; hypothetical protein 2131404 10974691 zobellia_1812 Zobellia galactanivorans hypothetical protein YP_004736253.1 2130352 D 63186 CDS YP_004736254.1 340617801 10974692 2131455..2131703 1 NC_015844.1 Hypothetical protein; hypothetical protein 2131703 10974692 zobellia_1813 Zobellia galactanivorans hypothetical protein YP_004736254.1 2131455 D 63186 CDS YP_004736255.1 340617802 10974693 2131822..2132484 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal GAF domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 2132484 10974693 zobellia_1814 Zobellia galactanivorans AraC family transcriptional regulator YP_004736255.1 2131822 D 63186 CDS YP_004736256.1 340617803 10974694 2132768..2133379 1 NC_015844.1 Contains a N-terminal region rich in glycine, reminiscent of the collagen triple helix repeats (GxxG); Prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Hypothetical protein; hypothetical protein 2133379 10974694 zobellia_1815 Zobellia galactanivorans hypothetical protein YP_004736256.1 2132768 D 63186 CDS YP_004736257.1 340617804 10974695 2133523..2134320 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 2134320 10974695 zobellia_1816 Zobellia galactanivorans hypothetical protein YP_004736257.1 2133523 D 63186 CDS YP_004736258.1 340617805 10974696 2134443..2135243 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 2135243 10974696 zobellia_1817 Zobellia galactanivorans lipoprotein YP_004736258.1 2134443 D 63186 CDS YP_004736259.1 340617806 10974697 complement(2135438..2136418) 1 NC_015844.1 Succinylglutamate desuccinylase catalyses the fifth and last step in arginine catabolism by the arginine succinyltransferase pathway. It hydrolyzes 2-N-succinylglutamate into succinate and glutamate. It binds one zinc ion as a cofactor. Localized in the cytoplasm.; High confidence in function and specificity; succinylglutamate desuccinylase 2136418 astE 10974697 astE Zobellia galactanivorans succinylglutamate desuccinylase YP_004736259.1 2135438 R 63186 CDS YP_004736260.1 340617807 10977565 complement(2136445..2137308) 1 NC_015844.1 RimK is responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6. This protein forms a dimer; Binds one ATP and 2 manganese ions by subunit; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S6 modification protein 2137308 rimK1 10977565 rimK1 Zobellia galactanivorans 30S ribosomal protein S6 modification protein YP_004736260.1 2136445 R 63186 CDS YP_004736261.1 340617808 10978465 complement(2137351..2137473) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2137473 10978465 zobellia_1820 Zobellia galactanivorans hypothetical protein YP_004736261.1 2137351 R 63186 CDS YP_004736262.1 340617809 10974699 2137621..2138289 1 NC_015844.1 Succinate dehydrogenase is a complex containing three subunits: a flavoprotein, an iron-sulfur protein and cytochrome b-558. It is involved in the citrate cycle and catalyzes the reaction: succinate + acceptor = fumarate + reduced acceptor. It uses a FAD as a cofactor. SdhC is the cytochrome b558 subunit. It binds two hemes. Features five transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; succinate dehydrogenase cytochrome b558 subunit 2138289 sdhC 10974699 sdhC Zobellia galactanivorans succinate dehydrogenase cytochrome b558 subunit YP_004736262.1 2137621 D 63186 CDS YP_004736263.1 340617810 10978574 2138292..2140295 1 NC_015844.1 Succinate dehydrogenase is a complex containing three subunits: a flavoprotein, an iron-sulfur protein and cytochrome b-558. It is involved in the citrate cycle and catalyzes the reaction: succinate + acceptor = fumarate + reduced acceptor. It uses a FAD as a cofactor. SdhA is the flavoprotein subunit. Localized in the cytoplasm.; High confidence in function and specificity; succinate dehydrogenase flavoprotein subunit 2140295 sdhA 10978574 sdhA Zobellia galactanivorans succinate dehydrogenase flavoprotein subunit YP_004736263.1 2138292 D 63186 CDS YP_004736264.1 340617811 10978572 2140302..2141048 1 NC_015844.1 Succinate dehydrogenase is a complex containing three subunits: a flavoprotein, an iron-sulfur protein and cytochrome b-558. It is involved in the citrate cycle and catalyzes the reaction: succinate + acceptor = fumarate + reduced acceptor. It uses a FAD as a cofactor. SdhB is the iron-sulfur subunit. Localized in the cytoplasm.; High confidence in function and specificity; succinate dehydrogenase iron-sulfur subunit 2141048 sdhB 10978572 sdhB Zobellia galactanivorans succinate dehydrogenase iron-sulfur subunit YP_004736264.1 2140302 D 63186 CDS YP_004736265.1 340617812 10978573 2141138..2141608 1 NC_015844.1 The Vsr (very short patch repair) proteins belong to a restriction-modification (R-M) system that recognise a TG mismatched base pair, generated after spontaneous deamination of methylated cytosines, and cleaves the phosphate backbone on the 5' side of the thymine. GT mismatches can lead to C-to-T transition mutations if not repaired. Vsr proteins repair the mismatches in favour of the G-containing strand; Belongs to the Vsr family; Localized in the cytoplasm; High confidence in function and specificity; very short patch repair protein 2141608 vsrA 10978573 vsrA Zobellia galactanivorans very short patch repair protein YP_004736265.1 2141138 D 63186 CDS YP_004736266.1 340617813 10978746 2141700..2142245 1 NC_015844.1 The catalytic diad of theses peptidases is constituted by two consecutive conserved residues, Cys His. The enzyme forms a hexameric ring structure, and the active site is proposed to be formed at the interface between three pairs of monomers; The peptidase monomer adopts a alpha/beta hydrolase fold; Belongs to the family 56 of the cysteine peptidases (C56); Localized in the cytoplasm; Specificity unclear; intracellular peptidase 2142245 10978746 zobellia_1825 Zobellia galactanivorans intracellular peptidase YP_004736266.1 2141700 D 63186 CDS YP_004736267.1 340617814 10974700 complement(2142620..2145508) 1 NC_015844.1 Conserved protein distantly related to glycoside hydrolases of the family 74 (GH74). Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; hypothetical protein 2145508 10974700 zobellia_1826 Zobellia galactanivorans hypothetical protein YP_004736267.1 2142620 R 63186 CDS YP_004736268.1 340617815 10974701 2145868..2147181 1 NC_015844.1 Xaa-Pro aminopeptidase catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide; PepP requires two co-catalytic ions of manganese; Belongs to the family 24 of the metallopeptidases (M24); Localized in the cytoplasm; High confidence in function and specificity; Xaa-Pro aminopeptidase, family M24 2147181 pepP2 10974701 pepP2 Zobellia galactanivorans Xaa-Pro aminopeptidase, family M24 YP_004736268.1 2145868 D 63186 CDS YP_004736269.1 340617816 10978328 2147191..2147961 1 NC_015844.1 The exonuclease III catalyses the cleavage in the 3'- to 5'-direction on double-stranded DNA to yield nucleoside 5'-phosphates. It also has an endonucleolytic activity near apurinic sites on DNA; Contains an Endonuclease/ Exonuclease/phosphatase domains; Belongs to the DNA repair enzymes AP family 1; Localized in the cytoplasm; High confidence in function and specificity; exodeoxyribonuclease III 2147961 xthA1 10978328 xthA1 Zobellia galactanivorans exodeoxyribonuclease III YP_004736269.1 2147191 D 63186 CDS YP_004736270.1 340617817 10978762 2147965..2148138 1 NC_015844.1 Hypothetical protein; hypothetical protein 2148138 10978762 zobellia_1829 Zobellia galactanivorans hypothetical protein YP_004736270.1 2147965 D 63186 CDS YP_004736271.1 340617818 10974702 2148296..2148985 1 NC_015844.1 Aquaporin Z is a channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Contains six transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity; aquaporin Z 2148985 aqpZ 10974702 aqpZ Zobellia galactanivorans aquaporin Z YP_004736271.1 2148296 D 63186 CDS YP_004736272.1 340617819 10977527 complement(2149029..2150315) 1 NC_015844.1 BraB is a component of the LIV-II transport system for branched-chain amino acids. It is specific for isoleucine, leucine and valine. The LIV-II transport system is coupled to sodium and lithium ions; Contains twelve transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity; branched chain amino acid transport system II carrier protein 2150315 braB 10977527 braB Zobellia galactanivorans branched chain amino acid transport system II carrier protein YP_004736272.1 2149029 R 63186 CDS YP_004736273.1 340617820 10977609 2150359..2150490 1 NC_015844.1 Hypothetical protein; hypothetical protein 2150490 10977609 zobellia_1832 Zobellia galactanivorans hypothetical protein YP_004736273.1 2150359 D 63186 CDS YP_004736274.1 340617821 10974704 complement(2150505..2150696) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2150696 10974704 zobellia_1833 Zobellia galactanivorans hypothetical protein YP_004736274.1 2150505 R 63186 CDS YP_004736275.1 340617822 10974705 2150737..2150913 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 2150913 10974705 zobellia_1834 Zobellia galactanivorans hypothetical protein YP_004736275.1 2150737 D 63186 CDS YP_004736276.1 340617823 10974706 complement(2151118..2152149) 1 NC_015844.1 The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Signal peptide cleaved between the residues 28 and 29; Localized in the periplasmic space; Function unclear; alpha/beta hydrolase-fold protein 2152149 10974706 zobellia_1835 Zobellia galactanivorans alpha/beta hydrolase-fold protein YP_004736276.1 2151118 R 63186 CDS YP_004736277.1 340617824 10974707 complement(2152156..2153205) 1 NC_015844.1 Thiamine-monophosphate kinase is involved in the biosynthesis of thiaminine pyrophosphate (coenzyme B1), an enzyme cofactor. It catalyzes the reaction: ATP + thiamine phosphate = ADP + thiamine diphosphate. Localized in the cytoplasm.; High confidence in function and specificity; thiamine-monophosphate kinase 2153205 thiL 10974707 thiL Zobellia galactanivorans thiamine-monophosphate kinase YP_004736277.1 2152156 R 63186 CDS YP_004736278.1 340617825 10978653 2153544..2153879 1 NC_015844.1 Protein SufA is a part of the suf operon (sufABCDSE). The six encoded proteins are arranged into two complexes (SufSE and SufBCD) and one protein . SufA acts as a scaffold protein in which Fe and S atoms are assembled into [FeS] cluster forms, which can then easily be transferred to apoproteins targets; The SUF system contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation; Localized in the cytoplasm; High confidence in function and specificity; protein SufA 2153879 sufA 10978653 sufA Zobellia galactanivorans protein SufA YP_004736278.1 2153544 D 63186 CDS YP_004736279.1 340617826 10978618 2153943..2155388 1 NC_015844.1 The protein SufB is part of the SufBCD complex which acts synergistically with SufE to stimulate the cysteine desulfurase activity (SufS). The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation; Localized in the cytoplasm; High confidence in function and specificity; protein SufB 2155388 sufB 10978618 sufB Zobellia galactanivorans protein SufB YP_004736279.1 2153943 D 63186 CDS YP_004736280.1 340617827 10978619 2155437..2156189 1 NC_015844.1 SufC is an ATPase with an unorthodox ATP-binding cassette (ABC)-like component. It is part of the SufBCD complex which contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation; Localized in the cytoplasm; High confidence in function and specificity; ATP-dependent transporter SufC 2156189 sufC 10978619 sufC Zobellia galactanivorans ATP-dependent transporter SufC YP_004736280.1 2155437 D 63186 CDS YP_004736281.1 340617828 10978620 2156263..2157579 1 NC_015844.1 The protein SufD is part of the SufBCD complex which acts synergistically with sufE to stimulate the cysteine desulfurase activity (SufS). The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation. Required for the stability of the fhuF protein; Localized in the cytoplasm; High confidence in function and specificity; protein SufD 2157579 sufD 10978620 sufD Zobellia galactanivorans protein SufD YP_004736281.1 2156263 D 63186 CDS YP_004736282.1 340617829 10978621 2157722..2158312 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Hypothetical protein; periplasmic protein 2158312 10978621 zobellia_1841 Zobellia galactanivorans periplasmic protein YP_004736282.1 2157722 D 63186 CDS YP_004736283.1 340617830 10974709 2158392..2159606 1 NC_015844.1 Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. SufS forms a homodimer and uses pyridoxal phosphate as a cofactor. It Interacts with SufE and the SufBCD complex. The interaction with SufE is required to mediate the direct transfer of the sulfur atom from the S-sulfanylcysteine; Localized in the cytoplasm; High confidence in function and specificity; cysteine desulfurase 2159606 sufS 10974709 sufS Zobellia galactanivorans cysteine desulfurase YP_004736283.1 2158392 D 63186 CDS YP_004736284.1 340617831 10978623 2159681..2160103 1 NC_015844.1 The protein SufE is a component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. SufE is an homodimeric scaffold protein that accepts sulfur atom from the cysteine desulfurase SufS and donates it to SufA. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules; Localized in the cytoplasm; High confidence in function and specificity; cysteine desulfuration protein SufE 2160103 sufE 10978623 sufE Zobellia galactanivorans cysteine desulfuration protein SufE YP_004736284.1 2159681 D 63186 CDS YP_004736285.1 340617832 10978622 2160158..2160487 1 NC_015844.1 Conserved protein belonging to the DUF59 family. Members of this family may all be components of ring hydroxylating complexes; Localized in the cytoplasm; Family membership; hypothetical protein 2160487 10978622 zobellia_1844 Zobellia galactanivorans hypothetical protein YP_004736285.1 2160158 D 63186 CDS YP_004736286.1 340617833 10974710 2160497..2161003 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2161003 10974710 zobellia_1845 Zobellia galactanivorans hypothetical protein YP_004736286.1 2160497 D 63186 CDS YP_004736287.1 340617834 10974711 2161070..2162002 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2162002 10974711 zobellia_1846 Zobellia galactanivorans periplasmic protein YP_004736287.1 2161070 D 63186 CDS YP_004736288.1 340617835 10974712 complement(2162189..2162404) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2162404 10974712 zobellia_1847 Zobellia galactanivorans hypothetical protein YP_004736288.1 2162189 R 63186 CDS YP_004736289.1 340617836 10974713 complement(2162899..2164110) 1 NC_015844.1 GTPase of unknown function; Localized in the cytoplasm; High confidence in function and specificity; GTP-binding protein HflX 2164110 hfiX 10974713 hfiX Zobellia galactanivorans GTP-binding protein HflX YP_004736289.1 2162899 R 63186 CDS YP_004736290.1 340617837 10977974 2164187..2165161 1 NC_015844.1 The Endonuclease/exonuclease/phosphatase domain is found in a large number of proteins including magnesium dependent endonucleases and phosphatases involved in intracellular signalling; Belongs to the Endonuclease/Exonuclease/phosphatase family; Localized in the cytoplasm; Family membership; endonuclease/exonuclease/phosphatase family protein 2165161 10977974 zobellia_1849 Zobellia galactanivorans endonuclease/exonuclease/phosphatase family protein YP_004736290.1 2164187 D 63186 CDS YP_004736291.1 340617838 10974714 complement(2165168..2165881) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2165881 10974714 zobellia_1850 Zobellia galactanivorans hypothetical protein YP_004736291.1 2165168 R 63186 CDS YP_004736292.1 340617839 10974716 2166066..2166908 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 27 and 28; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 2166908 10974716 zobellia_1851 Zobellia galactanivorans lipoprotein YP_004736292.1 2166066 D 63186 CDS YP_004736293.1 340617840 10974717 complement(2167086..2167559) 1 NC_015844.1 Methylated-DNA-[protein]-cysteine methyltransferase is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction since the enzyme is irreversibly inactivated and the methylated protein accumulates as a dead-end product; Localized in the cytoplasm; High confidence in function and specificity; methylated-DNA-[protein]-cysteine S-methyltransferase 2167559 ogtA 10974717 ogtA Zobellia galactanivorans methylated-DNA-[protein]-cysteine S-methyltransferase YP_004736293.1 2167086 R 63186 CDS YP_004736294.1 340617841 10978286 complement(2167609..2168715) 1 NC_015844.1 This protein contains a N-terminal region containing four transmembrane helices (DUF21 family) and two C-terminal CBS (cystathionine-beta-synthase) domains. CBS domains are small intracellular modules that pair together to form a stable globular domain. CBS domains have been shown to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet. They may play a regulatory role making proteins sensitive to adenosyl carrying ligands; Localized in the cytoplasmic membrane; Family membership; CBS family protein 2168715 10978286 zobellia_1853 Zobellia galactanivorans CBS family protein YP_004736294.1 2167609 R 63186 CDS YP_004736295.1 340617842 10974718 complement(2168766..2170055) 1 NC_015844.1 Serine peptidase belonging to the family S12, which includes D-Ala-D-Ala carboxypeptidase B and aminopeptidase DmpB. The active site residues Ser and Lys form the catalytic dyad and are found in the motif Ser-Xaa- Thr-Lys. Localized in the cytoplasm.; Specificity unclear; serine peptidase 2170055 10974718 zobellia_1854 Zobellia galactanivorans serine peptidase YP_004736295.1 2168766 R 63186 CDS YP_004736296.1 340617843 10974719 complement(2170125..2171114) 1 NC_015844.1 Delta-aminolevulinic acid dehydratase catalyzes the second step in the biosynthesis of heme, the condensation of two molecules of 5-aminolevulinate to form porphobilinogen. The enzyme is an oligomer composed of eight identical subunits. Each of the subunits binds a zinc ion. A lysine has been implicated in the catalytic mechanism. Localized in the cytoplasm.; High confidence in function and specificity; Delta-aminolevulinic acid dehydratase 2171114 hemB 10974719 hemB Zobellia galactanivorans Delta-aminolevulinic acid dehydratase YP_004736296.1 2170125 R 63186 CDS YP_004736297.1 340617844 10977964 2171187..2173829 1 NC_015844.1 Helicases are involved in unwinding nucleic acids; Contains a N-terminal ResIII domain or a DEAD domain, in the central part, a C-terminal helicase domain and two C-terminal transmembrane segments; Belongs to the superfamily II of helicases; Localized in the membrane cytoplasmic; Family membership; ATP-dependent helicase 2173829 10977964 zobellia_1856 Zobellia galactanivorans ATP-dependent helicase YP_004736297.1 2171187 D 63186 CDS YP_004736298.1 340617845 10974720 complement(2173816..2174466) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 30 and 31; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 2174466 10974720 zobellia_1857 Zobellia galactanivorans lipoprotein YP_004736298.1 2173816 R 63186 CDS YP_004736299.1 340617846 10974721 complement(2174459..2174629) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2174629 10974721 zobellia_1858 Zobellia galactanivorans hypothetical protein YP_004736299.1 2174459 R 63186 CDS YP_004736300.1 340617847 10974722 complement(2174647..2175549) 1 NC_015844.1 Coproporphyrinogen-III oxidase catalyzes the sixth step in the heme biosynthesis pathway: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. It forms a homodimer and binds one manganese as a cofactor. Localized in the cytoplasm.; High confidence in function and specificity; coproporphyrinogen-III oxidase 2175549 hemF 10974722 hemF Zobellia galactanivorans coproporphyrinogen-III oxidase YP_004736300.1 2174647 R 63186 CDS YP_004736301.1 340617848 10977968 complement(2175655..2176206) 1 NC_015844.1 Could acetylate the N-terminal aminoacid of a ribosomal protein; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; putative ribosomal protein N-acetyltransferase 2176206 10977968 zobellia_1860 Zobellia galactanivorans putative ribosomal protein N-acetyltransferase YP_004736301.1 2175655 R 63186 CDS YP_004736302.1 340617849 10974724 complement(2176220..2177254) 1 NC_015844.1 Uroporphyrinogen decarboxylase, the fifth enzyme of the heme biosynthetic pathway, catalyzes the sequential decarboxylation of the four acetyl side chains of uroporphyrinogen to yield coproporphyrinogen. It forms a homodimer. The monomer adopts a (beta/alpha)8-barrel fold with a deep active site cleft formed by loops at the C-terminal ends of the barrel strands. Localized in the cytoplasm.; High confidence in function and specificity; uroporphyrinogen decarboxylase 2177254 hemE 10974724 hemE Zobellia galactanivorans uroporphyrinogen decarboxylase YP_004736302.1 2176220 R 63186 CDS YP_004736303.1 340617850 10977967 complement(2177316..2178902) 1 NC_015844.1 This protein is a bifunctional enzyme with a N-terminal porphobilinogen deaminase (HemC) and a C-terminal uroporphyrinogen-III synthase (hemD). Both activities are involved in porphyrin and heme biosynthesis. HemC catalyzes the tetrapolymerization of the monopyrrole porphobilinogen into the hydroxymethylbilane pre- uroporphyrinogen in several discrete steps. It binds one dipyrromethane group covalently, as a cofactor. HemD catalyzes the hydrolysis of hydroxymethylbilane into uroporphyrinogen III. Therefore this bifunctional enzyme forms uroporphyrinogen III from porphobilinogen. Localized in the cytoplasm.; High confidence in function and specificity; Porphobilinogen deaminase / Uroporphyrinogen-III synthase 2178902 hemCD 10977967 hemCD Zobellia galactanivorans Porphobilinogen deaminase / Uroporphyrinogen-III synthase YP_004736303.1 2177316 R 63186 CDS YP_004736304.1 340617851 10977965 complement(2178899..2180155) 1 NC_015844.1 Glutamyl-tRNA-reductase is involved in porphyrin biosynthesis. It reduces glutamyl-tRNA to glutamate-1-semialdehyde during the first stage of tetrapyrrole biosynthesis by the C5 pathway. This enzyme required NADPH as a coenzyme. Localized in the cytoplasm.; High confidence in function and specificity; glutamyl-tRNA-reductase 2180155 hemA 10977965 hemA Zobellia galactanivorans glutamyl-tRNA-reductase YP_004736304.1 2178899 R 63186 CDS YP_004736305.1 340617852 10977963 2180361..2181254 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 2181254 10977963 zobellia_1864 Zobellia galactanivorans AraC family transcriptional regulator YP_004736305.1 2180361 D 63186 CDS YP_004736306.1 340617853 10974725 2181247..2181375 1 NC_015844.1 Hypothetical protein; hypothetical protein 2181375 10974725 zobellia_1865 Zobellia galactanivorans hypothetical protein YP_004736306.1 2181247 D 63186 CDS YP_004736307.1 340617854 10974726 2181420..2184227 1 NC_015844.1 The protein contains seven Fibronectin type 3 domains in its N-terminal part (42 to 713). No similarity with a known protein from the data bank was found with the 200 C-terminal residues; Signal peptide cleaved between the residues 23 and 24; Possible Lipoprotein localized in the outer membrane; Function unclear; hypothetical protein 2184227 10974726 zobellia_1866 Zobellia galactanivorans hypothetical protein YP_004736307.1 2181420 D 63186 CDS YP_004736308.1 340617855 10974727 complement(2184288..2184419) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2184419 10974727 zobellia_1867 Zobellia galactanivorans hypothetical protein YP_004736308.1 2184288 R 63186 CDS YP_004736309.1 340617856 10974728 complement(2184419..2185264) 1 NC_015844.1 Conserved protein belonging to the DUF1460 family. Features a signal peptide cleaved between the residues 19 and 20. Localized in the periplasm.; Family membership; hypothetical protein 2185264 10974728 zobellia_1868 Zobellia galactanivorans hypothetical protein YP_004736309.1 2184419 R 63186 CDS YP_004736310.1 340617857 10974729 complement(2185281..2188805) 1 NC_015844.1 Contains a N-terminal GumN domain (unknown function); Signal peptide cleaved between the residues 17 and 18; Localized in the periplasmic space; Family membership; periplasmic protein 2188805 10974729 zobellia_1869 Zobellia galactanivorans periplasmic protein YP_004736310.1 2185281 R 63186 CDS YP_004736311.1 340617858 10974730 complement(2188946..2190022) 1 NC_015844.1 Mechanosensitive channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation; Contains four transmembrane helices; Belongs to the small- conductance MS channels; Localized in the cytoplasmic membrane; Specificity unclear; small-conductance mechanosensitive channel 2190022 10974730 zobellia_1870 Zobellia galactanivorans small-conductance mechanosensitive channel YP_004736311.1 2188946 R 63186 CDS YP_004736312.1 340617859 10974732 2190284..2191315 1 NC_015844.1 Ferrochelatase catalyzes the last step in heme biosynthesis: the chelation of a ferrous ion to proto-porphyrin IX, to form protoheme. It contains a catalytic [Fe2S2] cluster. Localized in the cytoplasm.; High confidence in function and specificity; ferrochelatase 2191315 hemH 10974732 hemH Zobellia galactanivorans ferrochelatase YP_004736312.1 2190284 D 63186 CDS YP_004736313.1 340617860 10977969 2191346..2192734 1 NC_015844.1 Contains 12 transmembrane segments; Belongs to the multi antimicrobial extrusion (MATE) family; Localized in the cytoplasmic membrane; Family membership; multi antimicrobial extrusion family protein 2192734 10977969 zobellia_1872 Zobellia galactanivorans multi antimicrobial extrusion family protein YP_004736313.1 2191346 D 63186 CDS YP_004736314.1 340617861 10974733 complement(2192767..2194095) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 30 and 31; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2194095 10974733 zobellia_1873 Zobellia galactanivorans periplasmic protein YP_004736314.1 2192767 R 63186 CDS YP_004736315.1 340617862 10974734 complement(2194155..2195051) 1 NC_015844.1 Contains one central transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2195051 10974734 zobellia_1874 Zobellia galactanivorans membrane protein YP_004736315.1 2194155 R 63186 CDS YP_004736316.1 340617863 10974735 2195237..2195743 1 NC_015844.1 Contains five transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2195743 10974735 zobellia_1875 Zobellia galactanivorans membrane protein YP_004736316.1 2195237 D 63186 CDS YP_004736317.1 340617864 10974736 2195849..2197300 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains an HAMP domain and one transmembrane segments; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 2197300 10974736 zobellia_1876 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004736317.1 2195849 D 63186 CDS YP_004736318.1 340617865 10974737 2197362..2198141 1 NC_015844.1 Enzyme, also called crotonase, that participates to the fatty acid metabolism in the Butyrate/butanol-producing pathway.; High confidence in function and specificity; 3-hydroxybutyryl-CoA dehydratase 2198141 crtA 10974737 crtA Zobellia galactanivorans 3-hydroxybutyryl-CoA dehydratase YP_004736318.1 2197362 D 63186 CDS YP_004736319.1 340617866 10977677 2198177..2199727 1 NC_015844.1 Signal peptide cleaved between the rsidues 21 and 22; Probably localized in the periplasmic space; Hypothetical protein; hypothetical protein 2199727 10977677 zobellia_1878 Zobellia galactanivorans hypothetical protein YP_004736319.1 2198177 D 63186 CDS YP_004736320.1 340617867 10974738 2199747..2200859 1 NC_015844.1 Cytoplasmic protein that contains a SAM domain; hypothetical protein 2200859 10974738 zobellia_1879 Zobellia galactanivorans hypothetical protein YP_004736320.1 2199747 D 63186 CDS YP_004736321.1 340617868 10974739 2200926..2201486 1 NC_015844.1 Signal peptide cleaved between the residues 19 and 20; localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2201486 10974739 zobellia_1880 Zobellia galactanivorans periplasmic protein YP_004736321.1 2200926 D 63186 CDS YP_004736322.1 340617869 10974740 complement(2201581..2203005) 1 NC_015844.1 NAD(P)-dependent dehydrogenase. Belongs to the Rossmann fold family. Features a twin-arginine translocation signal peptide.; Specificity unclear; NAD(P)-dependent dehydrogenase 2203005 10974740 zobellia_1881 Zobellia galactanivorans NAD(P)-dependent dehydrogenase YP_004736322.1 2201581 R 63186 CDS YP_004736323.1 340617870 10974741 complement(2203081..2203773) 1 NC_015844.1 In metal-dependent phosphohydrolase, divalent cations are coordinated by conserved histidines and aspartates; Belongs to the HD superfamily; Localized in the cytoplasm; Family membership; metal-dependent phosphohydrolase 2203773 10974741 zobellia_1882 Zobellia galactanivorans metal-dependent phosphohydrolase YP_004736323.1 2203081 R 63186 CDS YP_004736324.1 340617871 10974742 complement(2203775..2204476) 1 NC_015844.1 1-acylglycerol-3-phosphate O-acyltransferase is involved in the phospholipid biosynthesis (second step). It converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position. The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate; Localized in the cytoplasm; High confidence in function and specificity; 1-acylglycerol-3-phosphate O-acyltransferase 2204476 plsC 10974742 plsC Zobellia galactanivorans 1-acylglycerol-3-phosphate O-acyltransferase YP_004736324.1 2203775 R 63186 CDS YP_004736325.1 340617872 10978354 complement(2204602..2205012) 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF1094 family; Localized in the cytoplasm; hypothetical protein 2205012 10978354 zobellia_1884 Zobellia galactanivorans hypothetical protein YP_004736325.1 2204602 R 63186 CDS YP_004736326.1 340617873 10974743 2205052..2205213 1 NC_015844.1 Hypothetical protein; hypothetical protein 2205213 10974743 zobellia_1885 Zobellia galactanivorans hypothetical protein YP_004736326.1 2205052 D 63186 CDS YP_004736327.1 340617874 10974744 2205221..2205958 1 NC_015844.1 The protein DjlA is a Regulatory dnaK co-chaperone. Contains a N-terminal transmembrane helix and a C-terminal DnaJ domain; Localized in the cytoplasmic membrane; High confidence in function and specificity; Co-chaperone DjlA 2205958 djlA 10974744 djlA Zobellia galactanivorans Co-chaperone DjlA YP_004736327.1 2205221 D 63186 CDS YP_004736328.1 340617875 10977747 2206004..2206588 1 NC_015844.1 Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2206588 10977747 zobellia_1887 Zobellia galactanivorans membrane protein YP_004736328.1 2206004 D 63186 CDS YP_004736329.1 340617876 10974745 2206713..2207162 1 NC_015844.1 Deoxycytidylate deaminase converts deoxycytidine 5'-monophosphate (dCMP) to deoxyuridine 5'-monophosphate and is a major supplier of the substrate for thymidylate synthase, an important enzyme in DNA synthesis. It adopts an alpha/beta/alpha three-layered fold and forms a homohexamer. Binds two zinc ions by subunit. Belongs to the cytidine and deoxycytidylate deaminase family. Localized in the cytoplasm.; High confidence in function and specificity; deoxycytidylate deaminase 2207162 10974745 zobellia_1888 Zobellia galactanivorans deoxycytidylate deaminase YP_004736329.1 2206713 D 63186 CDS YP_004736330.1 340617877 10974746 2207166..2208791 1 NC_015844.1 This enzyme is a modular protein with a N-terminal PDZ domain, a central carboxy-terminal processing peptidase and a C-terminal domain of unknown function. The catalytic module belongs to the family S41 of the peptidase. It shows specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala, but then cleaves at a variable distance from the C- terminus. PDZ domains are multifunctional protein-protein interaction modules. In many cases, PDZ domains bind to a signature motif ([FYST]-X-[FVA]) occurring at the very C- terminus of target proteins. Features an uncleaved signal peptide.; High confidence in function and specificity; carboxy-terminal processing peptidase 2208791 10974746 zobellia_1889 Zobellia galactanivorans carboxy-terminal processing peptidase YP_004736330.1 2207166 D 63186 CDS YP_004736331.1 340617878 10974747 complement(2208788..2209033) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2209033 10974747 zobellia_1890 Zobellia galactanivorans membrane protein YP_004736331.1 2208788 R 63186 CDS YP_004736332.1 340617879 10974748 complement(2209042..2209620) 1 NC_015844.1 Members of this family are integral membrane proteins. These proteins may be transporters; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Family membership; multiple antibiotic resistance-like protein 2209620 10974748 zobellia_1891 Zobellia galactanivorans multiple antibiotic resistance-like protein YP_004736332.1 2209042 R 63186 CDS YP_004736333.1 340617880 10974749 2209742..2210314 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2210314 10974749 zobellia_1892 Zobellia galactanivorans hypothetical protein YP_004736333.1 2209742 D 63186 CDS YP_004736334.1 340617881 10974750 complement(2210304..2212280) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains seven N-terminal tetratrico peptide repeats (TPR)and two transmembrane segments and; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 2212280 10974750 zobellia_1893 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004736334.1 2210304 R 63186 CDS YP_004736335.1 340617882 10974751 complement(2212287..2213021) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, that acts as transcriptional regulator; Family membership; two-component system-response regulator 2213021 10974751 zobellia_1894 Zobellia galactanivorans two-component system-response regulator YP_004736335.1 2212287 R 63186 CDS YP_004736336.1 340617883 10974752 2213438..2213557 1 NC_015844.1 Hypothetical protein; hypothetical protein 2213557 10974752 zobellia_1895 Zobellia galactanivorans hypothetical protein YP_004736336.1 2213438 D 63186 CDS YP_004736337.1 340617884 10974753 2213563..2214156 1 NC_015844.1 Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; hypothetical protein 2214156 10974753 zobellia_1896 Zobellia galactanivorans hypothetical protein YP_004736337.1 2213563 D 63186 CDS YP_004736338.1 340617885 10974754 complement(2214603..2214815) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2214815 10974754 zobellia_1897 Zobellia galactanivorans hypothetical protein YP_004736338.1 2214603 R 63186 CDS YP_004736339.1 340617886 10974755 2214891..2215526 1 NC_015844.1 Contains a signal peptide cleaved between 21 and 22; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 2215526 10974755 zobellia_1898 Zobellia galactanivorans hypothetical protein YP_004736339.1 2214891 D 63186 CDS YP_004736340.1 340617887 10974756 2215585..2218422 1 NC_015844.1 Protein containing three N-terminal tetratrico peptide repeats (TPRs) and a C-terminal conserved domain of unknown function. TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Contains a C-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; hypothetical protein 2218422 10974756 zobellia_1899 Zobellia galactanivorans hypothetical protein YP_004736340.1 2215585 D 63186 CDS YP_004736341.1 340617888 10974757 complement(2218431..2219159) 1 NC_015844.1 Contains one central transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2219159 10974757 zobellia_1900 Zobellia galactanivorans membrane protein YP_004736341.1 2218431 R 63186 CDS YP_004736342.1 340617889 10974760 complement(2219152..2219706) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released. They alter the specificity of promoter recognition. This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Localized in the cytoplasm; Specificity unclear; RNA polymerase ECF-type sigma factor 2219706 10974760 zobellia_1901 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004736342.1 2219152 R 63186 CDS YP_004736343.1 340617890 10974761 2219826..2221898 1 NC_015844.1 Protein that could adopt a right handed parallel beta-helix fold; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Hypothetical protein; hypothetical protein 2221898 10974761 zobellia_1902 Zobellia galactanivorans hypothetical protein YP_004736343.1 2219826 D 63186 CDS YP_004736344.1 340617891 10974762 2221950..2222297 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 2222297 10974762 zobellia_1903 Zobellia galactanivorans lipoprotein YP_004736344.1 2221950 D 63186 CDS YP_004736345.1 340617892 10974763 2222368..2222952 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2222952 10974763 zobellia_1904 Zobellia galactanivorans hypothetical protein YP_004736345.1 2222368 D 63186 CDS YP_004736346.1 340617893 10974764 2222986..2223351 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2223351 10974764 zobellia_1905 Zobellia galactanivorans membrane protein YP_004736346.1 2222986 D 63186 CDS YP_004736347.1 340617894 10974765 complement(2223412..2223528) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2223528 10974765 zobellia_1906 Zobellia galactanivorans hypothetical protein YP_004736347.1 2223412 R 63186 CDS YP_004736348.1 340617895 10974766 2223593..2223700 1 NC_015844.1 Hypothetical protein; hypothetical protein 2223700 10974766 zobellia_1907 Zobellia galactanivorans hypothetical protein YP_004736348.1 2223593 D 63186 CDS YP_004736349.1 340617896 10974767 2223718..2224200 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 2224200 10974767 zobellia_1908 Zobellia galactanivorans hypothetical protein YP_004736349.1 2223718 D 63186 CDS YP_004736350.1 340617897 10974768 2224205..2226169 1 NC_015844.1 Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2226169 10974768 zobellia_1909 Zobellia galactanivorans periplasmic protein YP_004736350.1 2224205 D 63186 CDS YP_004736351.1 340617898 10974769 2226471..2227457 1 NC_015844.1 Ribonucleoside-diphosphate reductase is an heterotetramer of two large and two small subunits. It catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. This gene codes the small subunit. It binds two iron ions by subunit. This complex is localized in the cytoplasm.; High confidence in function and specificity; ribonucleoside-diphosphate reductase, small subunit 2227457 rnrB1 10974769 rnrB1 Zobellia galactanivorans ribonucleoside-diphosphate reductase, small subunit YP_004736351.1 2226471 D 63186 CDS YP_004736352.1 340617899 10978487 2227580..2230066 1 NC_015844.1 Ribonucleoside-diphosphate reductase is an heterotetramer of two large and two small subunits. It catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. This gene codes the large subunit. This protein also features a N-terminal ATP cone domain, which is an evolutionarily mobile, ATP-binding regulatory domain. It binds either ATP (activating) or dATP (inhibitory). Substrate binding to the ATP cone domain is thought to alter the relative positions of the two subunits of Ribonucleoside-diphosphate reductase. This complex is localized in the cytoplasm.; High confidence in function and specificity; ribonucleoside-diphosphate reductase, large subunit 2230066 rnrA1 10978487 rnrA1 Zobellia galactanivorans ribonucleoside-diphosphate reductase, large subunit YP_004736352.1 2227580 D 63186 CDS YP_004736353.1 340617900 10978485 complement(2230484..2230624) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2230624 10978485 zobellia_1912 Zobellia galactanivorans hypothetical protein YP_004736353.1 2230484 R 63186 CDS YP_004736354.1 340617901 10974771 complement(2230876..2231853) 1 NC_015844.1 The Hydroxypyruvate isomerase catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the xylose isomerase-like TIM barrel family; Exported by the twin-arginine translocation pathway signal; High confidence in function and specificity; hydroxypyruvate isomerase 2231853 hyiA 10974771 hyiA Zobellia galactanivorans hydroxypyruvate isomerase YP_004736354.1 2230876 R 63186 CDS YP_004736355.1 340617902 10978011 complement(2231888..2232535) 1 NC_015844.1 Contains a putative putative lipoprotein signal peptide cleaved between the residues 29 and 30; Possibly localized in the cytoplasm or outer membrane; Conserved hypothetical protein; membrane protein 2232535 10978011 zobellia_1914 Zobellia galactanivorans membrane protein YP_004736355.1 2231888 R 63186 CDS YP_004736356.1 340617903 10974772 complement(2232535..2234247) 1 NC_015844.1 FAD-dependent oxidoreductase belonging to the GMC (glucose-methanol-choline) oxidoreductase family; Localized in the cytoplasm; Specificity unclear; FAD-dependent oxidoreductase 2234247 10974772 zobellia_1915 Zobellia galactanivorans FAD-dependent oxidoreductase YP_004736356.1 2232535 R 63186 CDS YP_004736357.1 340617904 10974773 2234388..2235383 1 NC_015844.1 Belongs to the Xylose isomerase-like TIM barrel superfamily; Contains a putative lipoprotein signal peptide cleaved between the residues 24 and 25, Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 2235383 10974773 zobellia_1916 Zobellia galactanivorans membrane protein YP_004736357.1 2234388 D 63186 CDS YP_004736358.1 340617905 10974774 2235406..2235849 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2235849 10974774 zobellia_1917 Zobellia galactanivorans hypothetical protein YP_004736358.1 2235406 D 63186 CDS YP_004736359.1 340617906 10974775 2235859..2237085 1 NC_015844.1 This integral membrane protein transports nucleosides with a high affinity. The transport mechanism is driven by proton motive force; Contains twelve transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; nucleoside/hydrogen symporter 2237085 10974775 zobellia_1918 Zobellia galactanivorans nucleoside/hydrogen symporter YP_004736359.1 2235859 D 63186 CDS YP_004736360.1 340617907 10974776 2237171..2238310 1 NC_015844.1 NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family; Adopts a Rossmann fold; Localized in the cytoplasm; Specificity unclear; NAD(P)-dependent oxidoreductase 2238310 10974776 zobellia_1919 Zobellia galactanivorans NAD(P)-dependent oxidoreductase YP_004736360.1 2237171 D 63186 CDS YP_004736361.1 340617908 10974777 complement(2238406..2241618) 1 NC_015844.1 Enzyme that catalyzes the hydrolysis of the beta- 1, 4 linkage at the terminal non-reducing of beta-D-galactosides, releasing a beta-D-galactose residue; Belongs to the family 2 of glycoside hydrolases (GH2); Signal peptide cleaved between residues 28 and 29; Possibly localized in the outer membrane; High confidence in function and specificity; beta-galactosidase 2241618 lacZ 10974777 lacZ Zobellia galactanivorans beta-galactosidase YP_004736361.1 2238406 R 63186 CDS YP_004736362.1 340617909 10978071 complement(2241728..2242192) 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF984 family; Localized in the cytoplasm; hypothetical protein 2242192 10978071 zobellia_1921 Zobellia galactanivorans hypothetical protein YP_004736362.1 2241728 R 63186 CDS YP_004736363.1 340617910 10974779 complement(2242321..2244024) 1 NC_015844.1 FAD-dependent oxidoreductase; Belongs to the GMC oxidoreductase family; Localized in the cytoplasm; Specificity unclear; FAD-dependent oxidoreductase 2244024 10974779 zobellia_1922 Zobellia galactanivorans FAD-dependent oxidoreductase YP_004736363.1 2242321 R 63186 CDS YP_004736364.1 340617911 10974780 2244183..2245235 1 NC_015844.1 This protein belongs to the xylose isomerase-like TIM barrel family; Adopts a TIM alpha/beta barrel fold; Localized in the cytoplasm; Family membership; TIM alpha/beta barrel protein 2245235 10974780 zobellia_1923 Zobellia galactanivorans TIM alpha/beta barrel protein YP_004736364.1 2244183 D 63186 CDS YP_004736365.1 340617912 10974781 2245355..2246110 1 NC_015844.1 Contains a domain of unknown function (DUF1080) that may adopt a concavalin-like or glucanase-like fold founded in glycoside hydrolases; Putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 2246110 10974781 zobellia_1924 Zobellia galactanivorans membrane protein YP_004736365.1 2245355 D 63186 CDS YP_004736366.1 340617913 10974782 2246330..2247187 1 NC_015844.1 This conserved protein contains a N-terminal domain Localized in the cytoplasm; Family membership; hypothetical protein 2247187 10974782 zobellia_1925 Zobellia galactanivorans hypothetical protein YP_004736366.1 2246330 D 63186 CDS YP_004736367.1 340617914 10974783 2247215..2247799 1 NC_015844.1 Guanylate kinase catalyzes the ATP-dependent phosphorylation of GMP into GDP. It is essential for recycling GMP and indirectly, cGMP. There is an ATP-binding site (P-loop) in the N-terminal section of GmkA. Localized in the cytoplasm.; High confidence in function and specificity; Guanylate kinase 2247799 gmkA 10974783 gmkA Zobellia galactanivorans Guanylate kinase YP_004736367.1 2247215 D 63186 CDS YP_004736368.1 340617915 10977938 2247832..2248416 1 NC_015844.1 Nicotinate-nucleotide adenylyltransferase is involved in the NAD(P) biosynthesis pathway. NadD catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). It forms a homodimer and uses ATP as a cofactor. Belongs to the cytidylyltransferase family. Localized in the cytoplasm.; High confidence in function and specificity; Nicotinate-nucleotide adenylyltransferase 2248416 nadD 10977938 nadD Zobellia galactanivorans Nicotinate-nucleotide adenylyltransferase YP_004736368.1 2247832 D 63186 CDS YP_004736369.1 340617916 10978221 complement(2248418..2249539) 1 NC_015844.1 Protein belonging to the amidohydrolase family, metal-dependent hydrolase superfamily; Adopts a TIM-barrel fold; Localized in the cytoplasm; Family membership; amidohydrolase 2249539 10978221 zobellia_1928 Zobellia galactanivorans amidohydrolase YP_004736369.1 2248418 R 63186 CDS YP_004736370.1 340617917 10974784 complement(2249658..2250083) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2250083 10974784 zobellia_1929 Zobellia galactanivorans hypothetical protein YP_004736370.1 2249658 R 63186 CDS YP_004736371.1 340617918 10974785 complement(2250181..2251125) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 2251125 10974785 zobellia_1930 Zobellia galactanivorans lipoprotein YP_004736371.1 2250181 R 63186 CDS YP_004736372.1 340617919 10974787 complement(2251238..2253487) 1 NC_015844.1 This integral membrane protein is distantly related with phosphate-sodium symporter. Contains eleven transmembrane helices; Localized in the cytoplasmic memnbrane; Family membership; phosphate transporter family protein 2253487 10974787 zobellia_1931 Zobellia galactanivorans phosphate transporter family protein YP_004736372.1 2251238 R 63186 CDS YP_004736373.1 340617920 10974788 2253859..2254218 1 NC_015844.1 Contains three MORN repeat variants. The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins. Signal peptide cleaved between the residues 21 and 22; Localized in periplasmic space; Conserved hypothetical protein; periplasmic protein 2254218 10974788 zobellia_1932 Zobellia galactanivorans periplasmic protein YP_004736373.1 2253859 D 63186 CDS YP_004736374.1 340617921 10974789 complement(2254294..2254686) 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 2254686 10974789 zobellia_1933 Zobellia galactanivorans hypothetical protein YP_004736374.1 2254294 R 63186 CDS YP_004736375.1 340617922 10974790 2254848..2256191 1 NC_015844.1 Deoxyguanosinetriphosphate triphosphohydrolase releases inorganic triphosphate, an unusual reaction product, from dGTP . Binds Mg2+ as a cofactor. The enzyme from Escherichia coli was shown to bind cooperatively to single stranded DNA. But the biological role of DgtA is still unknown. Localized in the cytoplasm.; High confidence in function and specificity; deoxyguanosinetriphosphate triphosphohydrolase 2256191 dgtA 10974790 dgtA Zobellia galactanivorans deoxyguanosinetriphosphate triphosphohydrolase YP_004736375.1 2254848 D 63186 CDS YP_004736376.1 340617923 10977742 complement(2256188..2257324) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2257324 10977742 zobellia_1935 Zobellia galactanivorans periplasmic protein YP_004736376.1 2256188 R 63186 CDS YP_004736377.1 340617924 10974791 complement(2257317..2259092) 1 NC_015844.1 DsxA catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP), a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis. It forms a homodimer and binds 1 thiamine pyrophosphate cofactor per subunit; Belongs to the transketolase family; Localized in the cytoplasm; High confidence in function and specificity; 1-deoxy-D-xylulose-5-phosphate synthase 2259092 dxsA 10974791 dxsA Zobellia galactanivorans 1-deoxy-D-xylulose-5-phosphate synthase YP_004736377.1 2257317 R 63186 CDS YP_004736378.1 340617925 10977773 2259270..2259719 1 NC_015844.1 tRNA adenosine deaminase generates inosine by deaminating the adenosine residue at the wobble position of tRNAArg-2. This modification is essential for the decoding system. TadA has an alpha/beta/alpha three- layered fold and forms a homodimer; Binds, via three conserved histidine and cysteine residues, a catalytic zinc ion; Belongs to the cytidine and deoxycytidylate deaminase family; Localized in the cytoplasm; High confidence in function and specificity; tRNA-specific adenosine deaminase 2259719 tadA 10977773 tadA Zobellia galactanivorans tRNA-specific adenosine deaminase YP_004736378.1 2259270 D 63186 CDS YP_004736379.1 340617926 10978634 complement(2259800..2259994) 1 NC_015844.1 Cold shock proteins (CSPs) help the cell to survive in temperatures lower than optimum growth temperature. CSPs may act as RNA chaperones by destabilizing RNA secondary structures, regulating ribosomal translation, rate of mRNA degradation and termination of transcription; Contains a 'cold-shock domain' (CSD) involved in the single-strand nucleic-acid binding; Localized in the cytoplasm; High confidence in function and specificity; cold shock protein 2259994 cspA2 10978634 cspA2 Zobellia galactanivorans cold shock protein YP_004736379.1 2259800 R 63186 CDS YP_004736380.1 340617927 10977686 complement(2260086..2260337) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2260337 10977686 zobellia_1939 Zobellia galactanivorans membrane protein YP_004736380.1 2260086 R 63186 CDS YP_004736381.1 340617928 10974792 complement(2260382..2262166) 1 NC_015844.1 Chloride channels constitute an evolutionarily well-conserved family of voltage-gated channels that are structurally unrelated to the other known voltage-gated channels. Features eleven transmembrane helices. Localized in the cytoplasmic membrane. Also features a C-terminal CBS (cystathionine-beta-synthase) domain. In chloride ion channels, the CBS domains have been implicated in intracellular targeting and trafficking, as well as in protein-protein interactions, but results vary with different channels.; High confidence in function and specificity; voltage-gated chloride channel 2262166 10974792 zobellia_1940 Zobellia galactanivorans voltage-gated chloride channel YP_004736381.1 2260382 R 63186 CDS YP_004736382.1 340617929 10974794 complement(2262226..2263980) 1 NC_015844.1 The aminoacyl-tRNA synthetases catalyse the attachment of an amino acid to its cognate transfer RNA molecule in a highly specific two-step reaction. Aspartyl-tRNA synthetase catalyzes the reaction : ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). AspS is an homodimer and is localized in the cytoplasm. It belongs to the class II of the aminoacyl-tRNA synthetases, which share an anti-parallel beta-sheet formation, flanked by alpha-helices.; High confidence in function and specificity; aspartyl-tRNA synthetase 2263980 aspS 10974794 aspS Zobellia galactanivorans aspartyl-tRNA synthetase YP_004736382.1 2262226 R 63186 CDS YP_004736383.1 340617930 10977564 2264170..2267172 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (25-99) and the Plug module (116-252) acting as a channel gate; The signal peptide is cleaved between the residues 23 and 24; Family membership; TonB-dependent Receptor 2267172 10977564 zobellia_1942 Zobellia galactanivorans TonB-dependent Receptor YP_004736383.1 2264170 D 63186 CDS YP_004736384.1 340617931 10974795 2267183..2268514 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 27 and 28; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 2268514 10974795 zobellia_1943 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736384.1 2267183 D 63186 CDS YP_004736385.1 340617932 10974796 complement(2268602..2272108) 1 NC_015844.1 Integral membrane protein involved in drug resistance that belongs to the acrB/acrD/acrF family; Contains 14 transmembrane segments and two large periplasmic domains (each exceeding 300 residues) between helices 1 and 2, and helices 9 and 10. The three transmembrane domains form a large, 30-wide central cavity that spans the cytoplasmic membrane and extends to the cytoplasm; Localized in the cytoplasmic membrane; Family membership; multidrug efflux transporter 2272108 10974796 zobellia_1944 Zobellia galactanivorans multidrug efflux transporter YP_004736385.1 2268602 R 63186 CDS YP_004736386.1 340617933 10974797 complement(2272098..2273282) 1 NC_015844.1 These membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics, solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmique membrane by a N-terminal transmembrane region; Family membership; membrane fusion protein 2273282 10974797 zobellia_1945 Zobellia galactanivorans membrane fusion protein YP_004736386.1 2272098 R 63186 CDS YP_004736387.1 340617934 10974798 complement(2273311..2274675) 1 NC_015844.1 The outer membrane efflux proteins (OEP) are composed of two repeats of OEP domain to form a trimeric channel continuous, solvent-accessible conduit that spans both the outer membrane and periplasmic space; May be specialized for the signal peptide independent extracellular secretion of a variety of substrates in Gram-negative bacteria (type I secretion system); Signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Family membership; outer membrane efflux protein 2274675 10974798 zobellia_1946 Zobellia galactanivorans outer membrane efflux protein YP_004736387.1 2273311 R 63186 CDS YP_004736388.1 340617935 10974799 complement(2274678..2275283) 1 NC_015844.1 Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership; TetR family transcriptional regulator 2275283 10974799 zobellia_1947 Zobellia galactanivorans TetR family transcriptional regulator YP_004736388.1 2274678 R 63186 CDS YP_004736389.1 340617936 10974800 complement(2275360..2275791) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; hypothetical protein 2275791 10974800 zobellia_1948 Zobellia galactanivorans hypothetical protein YP_004736389.1 2275360 R 63186 CDS YP_004736390.1 340617937 10974801 complement(2275810..2276349) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released. They alter the specificity of promoter recognition. This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Belongs to the sigma-70 factor family, ECF subfamily; Localized in the cytoplasm; Family membership; RNA polymerase ECF-type sigma factor 2276349 10974801 zobellia_1949 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004736390.1 2275810 R 63186 CDS YP_004736391.1 340617938 10974802 2276408..2276503 1 NC_015844.1 Hypothetical protein; hypothetical protein 2276503 10974802 zobellia_1950 Zobellia galactanivorans hypothetical protein YP_004736391.1 2276408 D 63186 CDS YP_004736392.1 340617939 10974803 2276491..2277465 1 NC_015844.1 IdsA is a bifunctional enzyme with dimethylallyltranstransferase and geranyltranstransferase activities. It is a key enzyme in isoprenoid biosynthesis which supplies sesquiterpene precursors for several classes of essential metabolites including sterols, dolichols, ubiquinones and carotenoids as well as substrates for farnesylation and geranylgeranylation of proteins. The enzyme is a homodimer of subunits, typically having two aspartate-rich motifs with two sets of substrate binding sites for an allylic diphosphate and isopentenyl diphosphate per homodimer; Localized in the cytoplasm; High confidence in function and specificity; bifunctional short chain isoprenyl diphosphate synthase 2277465 idsA 10974803 idsA Zobellia galactanivorans bifunctional short chain isoprenyl diphosphate synthase YP_004736392.1 2276491 D 63186 CDS YP_004736393.1 340617940 10978023 complement(2277482..2278651) 1 NC_015844.1 Catalyzes the double cyclization reaction which converts lycopene to beta-carotene; Involved in the carotenoid biosynthesis; contains a N-terminal transmembrane segment; Putatively localized in the cytoplasmic membrane; Family membership; Lycopene cyclase 2278651 crtY 10978023 crtY Zobellia galactanivorans Lycopene cyclase YP_004736393.1 2277482 R 63186 CDS YP_004736394.1 340617941 10977681 complement(2278712..2280985) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (26-104) and the Plug module (121-228) acting as a channel gate; The signal peptide is cleaved between the residues 23 and 24; Putatively involved in the colicin 1A and 1B uptake; Family membership; TonB-dependent Receptor 2280985 10977681 zobellia_1953 Zobellia galactanivorans TonB-dependent Receptor YP_004736394.1 2278712 R 63186 CDS YP_004736395.1 340617942 10974804 2281066..2281722 1 NC_015844.1 Metal dependent transcriptional regulator binds two divalent metal effectors per monomer via an dimerization domain with two metal-binding sites, upon which allosteric changes occur that moderate binding to the cognate DNA operators of a target gene via a N-terminal DtxR-type HTH domain; Contains an C-terminal SH3-like domain that characterizes the Fe(II)-regulators. It may act to stabilizing the dimeric form of the repressor; Family membership; transcriptional metalloregulator 2281722 10974804 zobellia_1954 Zobellia galactanivorans transcriptional metalloregulator YP_004736395.1 2281066 D 63186 CDS YP_004736396.1 340617943 10974805 2281724..2282545 1 NC_015844.1 Mediates zinc uptake. May also transport other divalent cations; Contains three N-terminal and three C-terminal transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity; heavy-metal cations permease 2282545 zupT 10974805 zupT Zobellia galactanivorans heavy-metal cations permease YP_004736396.1 2281724 D 63186 CDS YP_004736397.1 340617944 10978795 2282750..2283979 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains an N- terminal GAF domain; Seems localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 2283979 10978795 zobellia_1956 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004736397.1 2282750 D 63186 CDS YP_004736398.1 340617945 10974806 complement(2284009..2286642) 1 NC_015844.1 Contains a C-terminal domain displaying some similarities with sequences of the family 63 of glycoside hydrolases (Mannosyl-oligosaccharide glucosidase); Probably localized in the cytoplasm; hypothetical protein 2286642 10974806 zobellia_1957 Zobellia galactanivorans hypothetical protein YP_004736398.1 2284009 R 63186 CDS YP_004736399.1 340617946 10974807 complement(2286767..2286877) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2286877 10974807 zobellia_1958 Zobellia galactanivorans hypothetical protein YP_004736399.1 2286767 R 63186 CDS YP_004736400.1 340617947 10974808 2286898..2287329 1 NC_015844.1 Contains one transmembrane segment; Probably localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2287329 10974808 zobellia_1959 Zobellia galactanivorans hypothetical protein YP_004736400.1 2286898 D 63186 CDS YP_004736401.1 340617948 10974809 2287450..2287818 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 2287818 10974809 zobellia_1960 Zobellia galactanivorans hypothetical protein YP_004736401.1 2287450 D 63186 CDS YP_004736402.1 340617949 10974811 2287967..2288302 1 NC_015844.1 Contains three transmenbrane segments; Signal peptide cleaved between the residues 26 and 27; Localized in the cytoplasmic membrnane; Conserved hypothetical protein; membrane protein 2288302 10974811 zobellia_1961 Zobellia galactanivorans membrane protein YP_004736402.1 2287967 D 63186 CDS YP_004736403.1 340617950 10974812 complement(2288299..2289843) 1 NC_015844.1 Contains an N-terminal carboxypeptidase regulatory domain; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; hypothetical protein 2289843 10974812 zobellia_1962 Zobellia galactanivorans hypothetical protein YP_004736403.1 2288299 R 63186 CDS YP_004736404.1 340617951 10974813 complement(2289978..2290127) 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2290127 10974813 zobellia_1963 Zobellia galactanivorans membrane protein YP_004736404.1 2289978 R 63186 CDS YP_004736405.1 340617952 10974814 complement(2290129..2292366) 1 NC_015844.1 The FeoB protein is an integral membrane protein that belongs to the GTP-driven ferrous iron uptake system. The protein possesses an N-terminal 300 amino acyl residue hydrophilic domain that bears at its N-terminus a GTP binding motif that shows slow GTP hydrolysis. Binding of GTP is required for an efficient ferrous iron uptake. Nevertheless, GTP hydrolysis is essential for Fe2+ transport; Contains 8 C-terminal transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity; ferrous iron transport protein B 2292366 feoB 10974814 feoB Zobellia galactanivorans ferrous iron transport protein B YP_004736405.1 2290129 R 63186 CDS YP_004736406.1 340617953 10977828 complement(2292363..2292608) 1 NC_015844.1 FeoA is involved in ferrous iron (Fe2+)uptake in bacteria, but its exact function is still unknown. Localized in the cytoplasm.; High confidence in function and specificity; ferrous iron transport protein A 2292608 feoA 10977828 feoA Zobellia galactanivorans ferrous iron transport protein A YP_004736406.1 2292363 R 63186 CDS YP_004736407.1 340617954 10977827 complement(2292784..2293461) 1 NC_015844.1 Protein that consists of a SCO1/SenC domain; Contains a N-terminal transmembrane segment; Belongs to the SCO2/SenC family; Localized in the cytoplasmic membrane; Family membership; membrane protein 2293461 10977827 zobellia_1966 Zobellia galactanivorans membrane protein YP_004736407.1 2292784 R 63186 CDS YP_004736408.1 340617955 10974815 2293641..2294999 1 NC_015844.1 Peptidase EcfE degrades both heat shock sigma factors RpoE and RpoH in vitro. Features a N-terminal catalytic module belonging to the family 50 of the metallopeptidases followed by a PDZ module. Family M50 peptidases contain an HEXXH motif ; the glutamate has a catalytic role and the two histidines are ligands of a zinc ion. There is a more C-terminal Asp (in an invariant Asp-Gly motif) that is required for activity and is predicted to be a third ligand. Features four transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; peptidase EcfE, family M50 2294999 ecfE 10974815 ecfE Zobellia galactanivorans peptidase EcfE, family M50 YP_004736408.1 2293641 D 63186 CDS YP_004736409.1 340617956 10974030 complement(2295248..2296234) 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 12 of transposases; Localized in the cytoplasm; Family membership; transposase, family 12 2296234 10974030 zobellia_1969 Zobellia galactanivorans transposase, family 12 YP_004736409.1 2295248 R 63186 CDS YP_004736410.1 340617957 10974816 complement(2296221..2296574) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 2296574 10974816 zobellia_1970 Zobellia galactanivorans hypothetical protein YP_004736410.1 2296221 R 63186 CDS YP_004736411.1 340617958 10974817 2296935..2297177 1 NC_015844.1 Hypothetical protein; hypothetical protein 2297177 10974817 zobellia_1971 Zobellia galactanivorans hypothetical protein YP_004736411.1 2296935 D 63186 CDS YP_004736412.1 340617959 10974818 complement(2297520..2298404) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2298404 10974818 zobellia_1972 Zobellia galactanivorans hypothetical protein YP_004736412.1 2297520 R 63186 CDS YP_004736413.1 340617960 10974819 complement(2298513..2299502) 1 NC_015844.1 The Iota-carrageenases hydrolyse the 1,4-beta-D-galactosidic linkages in the iota-carrgeenan giving the tetramer as the predominant product; Belongs to the family 82 of glycoside hydrolases (GH82); This enzyme could to be localized in the outer membrane; High confidence in function and specificity; iota-carrageenase 2299502 cgiA3 10974819 cgiA3 Zobellia galactanivorans iota-carrageenase YP_004736413.1 2298513 R 63186 CDS YP_004736414.1 340617961 10977647 complement(2299948..2300136) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2300136 10977647 zobellia_1974 Zobellia galactanivorans hypothetical protein YP_004736414.1 2299948 R 63186 CDS YP_004736415.1 340617962 10974820 2300251..2301075 1 NC_015844.1 Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains two copies of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS- box proteins and bind to DNA; Localized in the cytoplasm; Family membership; universal stress protein 2301075 10974820 zobellia_1975 Zobellia galactanivorans universal stress protein YP_004736415.1 2300251 D 63186 CDS YP_004736416.1 340617963 10974821 2301254..2302888 1 NC_015844.1 Phosphoenolpyruvate carboxykinase (ATP) (PEPCK) catalyzes the formation of phosphoenolpyruvate by decarboxylation of oxaloacetate while hydrolyzing ATP, a rate limiting step in gluconeogenesis. PEPCK is allosterically activated by calcium and positively regulated by cAMP. It is involved in the glyoxylate bypass, an alternative to the tricarboxylic acid cycle; Localized in the cytoplasm; High confidence in function and specificity; phosphoenolpyruvate carboxykinase 2302888 pckA1 10974821 pckA1 Zobellia galactanivorans phosphoenolpyruvate carboxykinase YP_004736416.1 2301254 D 63186 CDS YP_004736417.1 340617964 10978312 2302961..2303068 1 NC_015844.1 Hypothetical protein; hypothetical protein 2303068 10978312 zobellia_1977 Zobellia galactanivorans hypothetical protein YP_004736417.1 2302961 D 63186 CDS YP_004736418.1 340617965 10974822 2303561..2304952 1 NC_015844.1 Conserved protein involved in exopolysaccharide biosynthesis. Its exact function is unknown. Contains five transmembrane helices. Localized in the cytoplasmic membrane.; Function unclear; exopolysaccharide production protein 2304952 10974822 zobellia_1978 Zobellia galactanivorans exopolysaccharide production protein YP_004736418.1 2303561 D 63186 CDS YP_004736419.1 340617966 10974823 2305062..2305823 1 NC_015844.1 Membrane protein likely involved in the export of expolysaccharide repeating units from the cytoplasm into the periplasm in a process analogous to O-unit export; Contains a C-terminal transmembrane helix; Prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the cytoplasmic membrane; Specificity unclear; polysaccharide export protein 2305823 10974823 zobellia_1979 Zobellia galactanivorans polysaccharide export protein YP_004736419.1 2305062 D 63186 CDS YP_004736420.1 340617967 10974824 2305926..2308331 1 NC_015844.1 May be involved in the production and the transport of exopolysaccharides; Contains a N-terminal transmembrane segment; Belongs to the etk/wzc family; Localized in the cytoplasmic membrane; Specificity unclear; tyrosine-protein kinase 2308331 wzcA 10974824 wzcA Zobellia galactanivorans tyrosine-protein kinase YP_004736420.1 2305926 D 63186 CDS YP_004736421.1 340617968 10978756 2308374..2309741 1 NC_015844.1 Contains eleven transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2309741 10978756 zobellia_1981 Zobellia galactanivorans membrane protein YP_004736421.1 2308374 D 63186 CDS YP_004736422.1 340617969 10974826 2309760..2311121 1 NC_015844.1 May be involved in the Lipopolysaccharide O antigen biosynthesis, translocating the nascent polysaccharidic O-antigen molecules and/or ligating them to lipid A core units; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Function unclear; O-antigen transporter 2311121 rfbX 10974826 rfbX Zobellia galactanivorans O-antigen transporter YP_004736422.1 2309760 D 63186 CDS YP_004736423.1 340617970 10978451 2311169..2312200 1 NC_015844.1 Contains a domain of unknown function DUF354. This family mainly contains proteins from Archae; Localized in the cytoplasm; hypothetical protein 2312200 10978451 zobellia_1983 Zobellia galactanivorans hypothetical protein YP_004736423.1 2311169 D 63186 CDS YP_004736424.1 340617971 10974827 2312228..2313532 1 NC_015844.1 GDP-mannose 6-dehydrogenase catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid . In Pseudomonas aeruginosa, this activated sugar is the precursor for alginate polymerization. AlgD belongs to the UDP-glucose/GDP- mannose dehydrogenase family, a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate. Localized in the cytoplasm.; High confidence in function and specificity; GDP-mannose 6-dehydrogenase 2313532 algD 10974827 algD Zobellia galactanivorans GDP-mannose 6-dehydrogenase YP_004736424.1 2312228 D 63186 CDS YP_004736425.1 340617972 10977502 complement(2313625..2314725) 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Localized in the cytoplasm.; Specificity unclear; glycosyltransferase 2314725 10977502 zobellia_1985 Zobellia galactanivorans glycosyltransferase YP_004736425.1 2313625 R 63186 CDS YP_004736426.1 340617973 10974828 2314969..2316159 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Localized in the cytoplasm.; Specificity unclear; glycosyltransferase 2316159 10974828 zobellia_1986 Zobellia galactanivorans glycosyltransferase YP_004736426.1 2314969 D 63186 CDS YP_004736427.1 340617974 10974829 2316263..2317198 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2317198 10974829 zobellia_1987 Zobellia galactanivorans hypothetical protein YP_004736427.1 2316263 D 63186 CDS YP_004736428.1 340617975 10974830 complement(2317267..2318364) 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; Belongs to the family 4 of the glycosyltransferases (GT4); Localized in the cytoplasm.; Specificity unclear; glycosyltransferase 2318364 10974830 zobellia_1988 Zobellia galactanivorans glycosyltransferase YP_004736428.1 2317267 R 63186 CDS YP_004736429.1 340617976 10974831 complement(2318361..2320268) 1 NC_015844.1 Polysaccharide lyase catalyses the eliminative cleavage of polysaccharides containing uronic acids. Belongs to the family 12 of the polysaccharide lyases. Up to now, the only known activity in family PL12 is heparin-sulfate lyase (EC 4.2.2.8). Localized in the cytoplasm.; Specificity unclear; polysaccharide lyase 2320268 10974831 zobellia_1989 Zobellia galactanivorans polysaccharide lyase YP_004736429.1 2318361 R 63186 CDS YP_004736430.1 340617977 10974832 2320733..2321779 1 NC_015844.1 Lipoprotein signal peptide cleaved between the residues 26 and 27; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 2321779 10974832 zobellia_1990 Zobellia galactanivorans lipoprotein YP_004736430.1 2320733 D 63186 CDS YP_004736431.1 340617978 10974834 2322036..2325008 1 NC_015844.1 Lipoprotein that contains, in its central part, four PKD domains. These domains are putatively involved in the protein-protein or proteins-polysaccharide interactions; Signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 2325008 10974834 zobellia_1991 Zobellia galactanivorans lipoprotein YP_004736431.1 2322036 D 63186 CDS YP_004736432.1 340617979 10974835 complement(2325091..2326407) 1 NC_015844.1 Contains eight transmembrane helices; Localized in the cytoplasmic membrane; hypothetical protein 2326407 10974835 zobellia_1992 Zobellia galactanivorans hypothetical protein YP_004736432.1 2325091 R 63186 CDS YP_004736433.1 340617980 10974836 complement(2326400..2327479) 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; Belongs to the family 2 of the glycosyltransferases (GT2); Contains two transmembrane helices in C-terminus; Localized in the cytoplasmic membrane; Specificity unclear; glycosyltransferase 2327479 10974836 zobellia_1993 Zobellia galactanivorans glycosyltransferase YP_004736433.1 2326400 R 63186 CDS YP_004736434.1 340617981 10974837 complement(2327649..2328614) 1 NC_015844.1 The carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides. These proteins fold into a 7-stranded beta/alpha barrel; Contains a C-terminal transmembrane helix; Belongs to the family 4 of carbohydrate esterases (CE4); Localized in the cytoplasmic membrane; Specificity unclear; carbohydrate esterase 2328614 10974837 zobellia_1994 Zobellia galactanivorans carbohydrate esterase YP_004736434.1 2327649 R 63186 CDS YP_004736435.1 340617982 10974838 complement(2328647..2329951) 1 NC_015844.1 The main role of amine oxidases is to provide a source of ammonium; Adopts a Rossmann fold; Uses FAD as prosthetic group; Localized in the cytoplasm; Specificity unclear; FAD-dependent amine oxidoreductase 2329951 10974838 zobellia_1995 Zobellia galactanivorans FAD-dependent amine oxidoreductase YP_004736435.1 2328647 R 63186 CDS YP_004736436.1 340617983 10974839 complement(2329948..2330952) 1 NC_015844.1 Conserved protein belonging to the NAD(P)-dependent sugar epimerase/dehydratase family, which is included in the Rossmann fold superfamily; Localized in the cytoplasm; Family membership; NAD(P)-dependent sugar epimerase/dehydratase 2330952 10974839 zobellia_1996 Zobellia galactanivorans NAD(P)-dependent sugar epimerase/dehydratase YP_004736436.1 2329948 R 63186 CDS YP_004736437.1 340617984 10974840 2331349..2332026 1 NC_015844.1 The generic name 'NUDIX hydrolases' corresponds to pyrophosphatases cleaving a NUcleoside DIphosphate linked to some other moiety X. These enzymes hydrolyze diverse nucleoside diphosphate derivatives (including ADP-ribose, GDP- mannose, TDP-glucose, NADH, UDP-sugars, dNTP and NTP). Localized in the cytoplasm.; Specificity unclear; NUDIX hydrolase 2332026 10974840 zobellia_1997 Zobellia galactanivorans NUDIX hydrolase YP_004736437.1 2331349 D 63186 CDS YP_004736438.1 340617985 10974841 2332126..2333820 1 NC_015844.1 Ribulokinase catalyzes the phosphorylation of ribulose . This is the second step of the arabinose catabolism. AraB belongs to the FGGY family of the carbohydrate kinases.; High confidence in function and specificity; Ribulokinase 2333820 araB 10974841 araB Zobellia galactanivorans Ribulokinase YP_004736438.1 2332126 D 63186 CDS YP_004736439.1 340617986 10977529 2333813..2334517 1 NC_015844.1 L-ribulose-5-phosphate 4-epimerase catalyzes the conversion of L-ribulose 5-phosphate into D-xylulose 5-phosphate. This is the third step of the L-arabinose catabolism. AraD belongs to the class II aldolase family. Binds one zinc ion by subunit. Localized in the cytoplasm.; High confidence in function and specificity; L-ribulose-5-phosphate 4-epimerase 2334517 araD 10977529 araD Zobellia galactanivorans L-ribulose-5-phosphate 4-epimerase YP_004736439.1 2333813 D 63186 CDS YP_004736440.1 340617987 10977530 2334542..2336107 1 NC_015844.1 Actively transports glucose into cells by Na(+) cotransport. Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of pro- and eukaryotic cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient is used to drive solute accumulation against a concentration gradient. Features fourteen transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; sodium/glucose symporter SglT 2336107 sglT 10977530 sglT Zobellia galactanivorans sodium/glucose symporter SglT YP_004736440.1 2334542 D 63186 CDS YP_004736441.1 340617988 10978585 2336131..2337633 1 NC_015844.1 L-arabinose isomerase catalyzes the conversion of L-arabinose into L-ribulose. This reaction is the first step in the pathway of L-arabinose utilisation as a carbon source. Localized in the cytoplasm.; High confidence in function and specificity; L-arabinose isomerase 2337633 araA 10978585 araA Zobellia galactanivorans L-arabinose isomerase YP_004736441.1 2336131 D 63186 CDS YP_004736442.1 340617989 10977528 complement(2337642..2338832) 1 NC_015844.1 Contains a central transmembrane helix; Localized in the cytoplasmic membrane; hypothetical protein 2338832 10977528 zobellia_2002 Zobellia galactanivorans hypothetical protein YP_004736442.1 2337642 R 63186 CDS YP_004736443.1 340617990 10974845 2338948..2342181 1 NC_015844.1 This protein has a modular architecture with a N-terminal cytochrome C (residues 19-136) and three domains of unknown function: a DUF1549 domain which includes a second cytochrome C (161-395), a central domain adopting a jelly roll fold (concavalin A-like, 449-666) and a C-terminal DUF1553 domain (762-1077). Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes; Prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the cytoplasmic and/or outer membrane; Function unclear; cytochrome c-containing protein 2342181 10974845 zobellia_2003 Zobellia galactanivorans cytochrome c-containing protein YP_004736443.1 2338948 D 63186 CDS YP_004736444.1 340617991 10974846 2342191..2343669 1 NC_015844.1 Contains a domain of unknown function DUF1501; Belongs to the alkaline-phosphatase clan; Contains a twin-arginine signal peptide; Localized in the periplasmic space; Family membership; periplasmic protein 2343669 10974846 zobellia_2004 Zobellia galactanivorans periplasmic protein YP_004736444.1 2342191 D 63186 CDS YP_004736445.1 340617992 10974847 2343675..2344742 1 NC_015844.1 This protein likely adopts a beta-propeller fold; Contains a twin-arginine signal peptide; Localized in the periplasmic space; Family membership; hypothetical protein 2344742 10974847 zobellia_2005 Zobellia galactanivorans hypothetical protein YP_004736445.1 2343675 D 63186 CDS YP_004736446.1 340617993 10974848 2344805..2345398 1 NC_015844.1 Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. This protein may also be involved in the regulation of purine biosynthesis; Localized in the cytoplasm; High confidence in function and specificity; endoribonuclease L-PSP 2345398 10974848 zobellia_2006 Zobellia galactanivorans endoribonuclease L-PSP YP_004736446.1 2344805 D 63186 CDS YP_004736447.1 340617994 10974849 2345402..2346412 1 NC_015844.1 The substrate-binding periplasmic subunit is a extracytoplasmic solute receptor, a component of a tripartite ATP-independent periplasmic (TRAP) transport system. The two other components of the system are two transmembrane proteins. TRAP transporters are secondary carriers that use an electrochemical H+ gradient as the driving force for transport; Contains a lipoprotein signal peptide cleaved between the residues 26 and 27; Anchored in the cytoplasmic membrane, in periplasmic side; Specificity unclear; TRAP transporter substrate-binding periplasmic subunit 2346412 10974849 zobellia_2007 Zobellia galactanivorans TRAP transporter substrate-binding periplasmic subunit YP_004736447.1 2345402 D 63186 CDS YP_004736448.1 340617995 10974850 2346402..2346866 1 NC_015844.1 The small permease subunit is a component of a tripartite ATP-independent periplasmic (TRAP) transport system. The two other components of the system are a second transmembrane proteins and a extracytoplasmic solute receptor. TRAP transporters are secondary carriers that use an electrochemical H+ gradient as the driving force for transport; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; TRAP transporter small permease subunit 2346866 10974850 zobellia_2008 Zobellia galactanivorans TRAP transporter small permease subunit YP_004736448.1 2346402 D 63186 CDS YP_004736449.1 340617996 10974851 2346863..2348137 1 NC_015844.1 The large permease subunit is a component of a tripartite ATP-independent periplasmic (TRAP) transport system. The two other components of the system are a second transmembrane proteins and a extracytoplasmic solute receptor. TRAP transporters are secondary carriers that use an electrochemical H+ gradient as the driving force for transport; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; TRAP transporter large permease subunit 2348137 10974851 zobellia_2009 Zobellia galactanivorans TRAP transporter large permease subunit YP_004736449.1 2346863 D 63186 CDS YP_004736450.1 340617997 10974852 2348149..2348967 1 NC_015844.1 Putative esterase. Adopts an alpha/beta hydrolase fold; Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Specificity unclear; esterase 2348967 10974852 zobellia_2010 Zobellia galactanivorans esterase YP_004736450.1 2348149 D 63186 CDS YP_004736451.1 340617998 10974032 complement(2349206..2349313) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2349313 10974032 zobellia_2012 Zobellia galactanivorans hypothetical protein YP_004736451.1 2349206 R 63186 CDS YP_004736452.1 340617999 10974855 complement(2349481..2350173) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2350173 10974855 zobellia_2013 Zobellia galactanivorans hypothetical protein YP_004736452.1 2349481 R 63186 CDS YP_004736453.1 340618000 10974856 2350657..2352114 1 NC_015844.1 Arginine decarboxylase catalyzes the biosynthesis of agmatine from arginine. It is involved in the putrescine biosynthesis pathway. Uses the pyridoxal- phosphate as prosthetic group linked to a conserved lysine residue; Binds a magnesium ion; Localized in the cytoplasm; High confidence in function and specificity; arginine decarboxylase 2352114 speA 10974856 speA Zobellia galactanivorans arginine decarboxylase YP_004736453.1 2350657 D 63186 CDS YP_004736454.1 340618001 10978603 2352130..2353071 1 NC_015844.1 Agmatinase hydrolyses agmatine to putrescine, the precursor for the biosynthesis of higher polyamines, spermidine and spermine; Adopts a 3-layer alpha-beta-alpha fold; Binds a manganese ion; Belongs to the arginase family; Localized in the cytoplasm; High confidence in function and specificity; agmatinase 2353071 speB 10978603 speB Zobellia galactanivorans agmatinase YP_004736454.1 2352130 D 63186 CDS YP_004736455.1 340618002 10978604 2353058..2354035 1 NC_015844.1 Deoxyhypusine synthase transfers alkyl or aryl groups on an acceptor molecule. It likely catalyzes the NAD(+)-dependent dehydrogenation of spermidine, resulting in the formation of an enzyme-imine intermediate by transfer of the 4-aminobutylidene group from dehydrospermidine to the active site lysine residue. The 4-aminobutylidene group is then transfered from the enzyme intermediate to an acceptor molecule; Localized in the cytoplasm; Specificity unclear; deoxyhypusine synthase-like protein 2354035 10978604 zobellia_2016 Zobellia galactanivorans deoxyhypusine synthase-like protein YP_004736455.1 2353058 D 63186 CDS YP_004736456.1 340618003 10974857 2354032..2354358 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2354358 10974857 zobellia_2017 Zobellia galactanivorans hypothetical protein YP_004736456.1 2354032 D 63186 CDS YP_004736457.1 340618004 10974858 2354473..2356002 1 NC_015844.1 Modular protein composed of a N-terminal N-acetyltransferase domain of the GNAT family (residues 2-224) and a C-terminal Carbon-Nitrogen hydrolase domain (225-508). The Gcn5-related N-acetyltransferases (GNAT) catalyze the transfer of the acetyl from the Coenzyme A donor to a primary amine of an acceptor. The carbon-nitrogen hydrolase domain is involved in the reduction of organic nitrogen compounds and ammonia production; Localized in the cytoplasm; Specificity unclear; N-acetyltransferase / carbon-nitrogen hydrolase 2356002 10974858 zobellia_2018 Zobellia galactanivorans N-acetyltransferase / carbon-nitrogen hydrolase YP_004736457.1 2354473 D 63186 CDS YP_004736458.1 340618005 10974859 2356004..2357374 1 NC_015844.1 RimK is responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6. This protein forms a dimer; Binds one ATP and 2 manganese ions by subunit; Contains a N-terminal domain of unknown function (DUF785); Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S6 modification protein 2357374 rimK2 10974859 rimK2 Zobellia galactanivorans 30S ribosomal protein S6 modification protein YP_004736458.1 2356004 D 63186 CDS YP_004736459.1 340618006 10978466 complement(2357431..2357556) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2357556 10978466 zobellia_2020 Zobellia galactanivorans hypothetical protein YP_004736459.1 2357431 R 63186 CDS YP_004736460.1 340618007 10974861 2357868..2358362 1 NC_015844.1 SCP-like extracellular proteins have been proposed to be a calcium ion chelating serine proteases. The Calcium-chelating function would fit with the various signalling processes where these proteins are involved and also the structural evidence of a conserved pocket containing two histidines and a glutamate; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Function unclear; SCP-like extracellular protein 2358362 10974861 zobellia_2021 Zobellia galactanivorans SCP-like extracellular protein YP_004736460.1 2357868 D 63186 CDS YP_004736461.1 340618008 10974862 2358691..2361714 1 NC_015844.1 Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2361714 10974862 zobellia_2022 Zobellia galactanivorans periplasmic protein YP_004736461.1 2358691 D 63186 CDS YP_004736462.1 340618009 10974863 2361756..2362679 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; hypothetical protein 2362679 10974863 zobellia_2023 Zobellia galactanivorans hypothetical protein YP_004736462.1 2361756 D 63186 CDS YP_004736463.1 340618010 10974864 2362692..2364644 1 NC_015844.1 This protein has a modular architecture composed of a N-terminal TPR motif, a central beta-propeller domain, encompassing three WD40 repeats, and a C-terminal OmpA domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan. The tetratrico peptide repeat (TPR) is a structural motif, which mediates proteinprotein interactions; Contains a signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Function unclear; OmpA-like outer membrane protein 2364644 10974864 zobellia_2024 Zobellia galactanivorans OmpA-like outer membrane protein YP_004736463.1 2362692 D 63186 CDS YP_004736464.1 340618011 10974865 complement(2364745..2365686) 1 NC_015844.1 This enzyme belongs to the NAD-dependent epimerase/dehydratase family, which is included in the Rossmann fold Superfamily. In this family, the proteins use nucleotide-sugar substrates for a variety of chemical reactions; Localized in the cytoplasm; Family membership; NAD-dependent epimerase/dehydratase 2365686 10974865 zobellia_2025 Zobellia galactanivorans NAD-dependent epimerase/dehydratase YP_004736464.1 2364745 R 63186 CDS YP_004736465.1 340618012 10974866 2365751..2366245 1 NC_015844.1 Containsan uncleaved signal sequence; Localized in the cytoplasmic membrane; hypothetical protein 2366245 10974866 zobellia_2026 Zobellia galactanivorans hypothetical protein YP_004736465.1 2365751 D 63186 CDS YP_004736466.1 340618013 10974867 complement(2366310..2367611) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 2367611 10974867 zobellia_2027 Zobellia galactanivorans hypothetical protein YP_004736466.1 2366310 R 63186 CDS YP_004736467.1 340618014 10974868 complement(2367762..2368466) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; hypothetical protein 2368466 10974868 zobellia_2028 Zobellia galactanivorans hypothetical protein YP_004736467.1 2367762 R 63186 CDS YP_004736468.1 340618015 10974869 complement(2368619..2369017) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2369017 10974869 zobellia_2029 Zobellia galactanivorans hypothetical protein YP_004736468.1 2368619 R 63186 CDS YP_004736469.1 340618016 10974870 complement(2369108..2369911) 1 NC_015844.1 Likely contains a NAD(P) binding protein; Localized in the cytoplasm; hypothetical protein 2369911 10974870 zobellia_2030 Zobellia galactanivorans hypothetical protein YP_004736469.1 2369108 R 63186 CDS YP_004736470.1 340618017 10974872 complement(2369904..2372189) 1 NC_015844.1 These peptidases have co-catalytic zinc ions. Each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water. Two catalytic motifs are conserved: His-Xaa-Asp and Glu-Glu. Contains 8 transmembrane helices. Belongs to the M28 family of peptidases; Localized in the cytoplasmic membrane; Specificity unclear; metallopeptidase 2372189 10974872 zobellia_2031 Zobellia galactanivorans metallopeptidase YP_004736470.1 2369904 R 63186 CDS YP_004736471.1 340618018 10974873 2372395..2372862 1 NC_015844.1 CBS domains are small intracellular modules that pair together to form a stable globular domain. They have been shown to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet; Localized in the cytoplasm; Family membership; CBS domain-containing protein 2372862 10974873 zobellia_2032 Zobellia galactanivorans CBS domain-containing protein YP_004736471.1 2372395 D 63186 CDS YP_004736472.1 340618019 10974874 complement(2372956..2373306) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2373306 10974874 zobellia_2033 Zobellia galactanivorans hypothetical protein YP_004736472.1 2372956 R 63186 CDS YP_004736473.1 340618020 10974875 complement(2373308..2373799) 1 NC_015844.1 Contains a signal peptide cleaved between residues 17 and 18; Localized in the periplasmic space; hypothetical protein 2373799 10974875 zobellia_2034 Zobellia galactanivorans hypothetical protein YP_004736473.1 2373308 R 63186 CDS YP_004736474.1 340618021 10974876 complement(2373861..2374436) 1 NC_015844.1 Together with two other proteins, mcbE and mcbF, this protein causes immunity to the peptide antibiotic microcin, which inhibits DNA replication by induction of the SOS repair system. McbG alone can provide some protection; Localized in the cytoplasm; High confidence in function and specificity; protein mcbG 2374436 mcbG 10974876 mcbG Zobellia galactanivorans protein mcbG YP_004736474.1 2373861 R 63186 CDS YP_004736475.1 340618022 10978127 complement(2374515..2374727) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2374727 10978127 zobellia_2036 Zobellia galactanivorans hypothetical protein YP_004736475.1 2374515 R 63186 CDS YP_004736476.1 340618023 10974877 2374738..2374860 1 NC_015844.1 Hypothetical protein; hypothetical protein 2374860 10974877 zobellia_2037 Zobellia galactanivorans hypothetical protein YP_004736476.1 2374738 D 63186 CDS YP_004736477.1 340618024 10974878 2375004..2378048 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (33-106) and the Plug module (122-228) acting as a channel gate; The signal peptide is cleaved between the residues 31 and 32; Family membership; TonB-dependent Receptor 2378048 10974878 zobellia_2038 Zobellia galactanivorans TonB-dependent Receptor YP_004736477.1 2375004 D 63186 CDS YP_004736478.1 340618025 10974879 2378059..2379708 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 2379708 10974879 zobellia_2039 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736478.1 2378059 D 63186 CDS YP_004736479.1 340618026 10974880 complement(2379799..2380425) 1 NC_015844.1 Chloramphenicol O-acetyltransferase is an effector of chloramphenicol resistance in bacteria. It converts the chloramphenicol to chloramphenicol 3-acetate; Forms a homotrimer; Localized in the cytoplasm; High confidence in function and specificity; chloramphenicol O-acetyltransferase 2380425 cmlA 10974880 cmlA Zobellia galactanivorans chloramphenicol O-acetyltransferase YP_004736479.1 2379799 R 63186 CDS YP_004736480.1 340618027 10977660 2380623..2381240 1 NC_015844.1 Conserved hypothetical protein including an N-terminal region rich in glycine, reminiscent of the collagen triple helix repeats (GxxG); Signal peptide of lipoprotein cleaved between the residues 21 and 22; Localized in the outer membrane; Function unclear; lipoprotein 2381240 10977660 zobellia_2041 Zobellia galactanivorans lipoprotein YP_004736480.1 2380623 D 63186 CDS YP_004736481.1 340618028 10974882 complement(2381279..2381749) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2381749 10974882 zobellia_2042 Zobellia galactanivorans hypothetical protein YP_004736481.1 2381279 R 63186 CDS YP_004736482.1 340618029 10974883 complement(2381809..2382324) 1 NC_015844.1 Contains a putative signal peptide cleaved between residues 27 and 28; Putatively localized in the periplasmic space; Hypothetical protein; hypothetical protein 2382324 10974883 zobellia_2043 Zobellia galactanivorans hypothetical protein YP_004736482.1 2381809 R 63186 CDS YP_004736483.1 340618030 10974884 complement(2382541..2383110) 1 NC_015844.1 Contains a signal peptide cleaved between residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2383110 10974884 zobellia_2044 Zobellia galactanivorans periplasmic protein YP_004736483.1 2382541 R 63186 CDS YP_004736484.1 340618031 10974885 complement(2383421..2383822) 1 NC_015844.1 Contains one transmembrane helix (residues 78-100); Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2383822 10974885 zobellia_2045 Zobellia galactanivorans hypothetical protein YP_004736484.1 2383421 R 63186 CDS YP_004736485.1 340618032 10974886 complement(2383906..2384697) 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 2384697 10974886 zobellia_2046 Zobellia galactanivorans hypothetical protein YP_004736485.1 2383906 R 63186 CDS YP_004736486.1 340618033 10974887 complement(2384887..2385396) 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 2385396 10974887 zobellia_2047 Zobellia galactanivorans hypothetical protein YP_004736486.1 2384887 R 63186 CDS YP_004736487.1 340618034 10974888 2385617..2385949 1 NC_015844.1 Single-stranded DNA-binding protein (SSB) is essential for replication of the chromosome. It is also involved in DNA recombination and repair. This protein forms a homotetramer. Localized in the cytoplasm.; High confidence in function and specificity; single-stranded DNA-binding protein 2385949 ssb2 10974888 ssb2 Zobellia galactanivorans single-stranded DNA-binding protein YP_004736487.1 2385617 D 63186 CDS YP_004736488.1 340618035 10978613 2386061..2388160 1 NC_015844.1 RecQ is a ATP-dependent DNA helicase involved in genome maintenance in the RecF recombination pathway; RecQ unwinds paired DNA, translocating in a 3' to 5' direction; The expression of RecQ gene is under the regulation of the SOS system. Contains a DEAD/H box and a HRDC domain; Belongs to superfamily II of helicases, RecQ family; Localized in the cytoplasm; High confidence in function and specificity; ATP-dependent DNA helicase RecQ 2388160 recQ1 10978613 recQ1 Zobellia galactanivorans ATP-dependent DNA helicase RecQ YP_004736488.1 2386061 D 63186 CDS YP_004736489.1 340618036 10978447 complement(2388193..2389482) 1 NC_015844.1 Phenylacetate-coenzyme A ligase catalyzes the activation of phenylacetic acid to phenylacetyl-CoA. It is the first step of the Phenylacetic acid aerobic catabolism; Also acts, more slowly, on acetate, propanoate and butanoate, but not on hydroxy derivatives of phenylacetate and related compounds; Activated by cAMP receptor protein (CRP); Contains an AMP binding motif; Localized in the cytoplasm; High confidence in function and specificity; phenylacetate-coenzyme A ligase 2389482 paaK 10978447 paaK Zobellia galactanivorans phenylacetate-coenzyme A ligase YP_004736489.1 2388193 R 63186 CDS YP_004736490.1 340618037 10978293 complement(2389483..2391159) 1 NC_015844.1 Peptidase family C45 contains autolytic endopeptidases. The active site cysteine becomes the new N-terminus following the autolytic cleavage. Features a C-terminal TPR domain. Signal peptide of lipoprotein cleaved between the residues 21 and 22. Localized in the cytoplasmic membrane.; Specificity unclear; cysteine endopeptidase, family c45 2391159 10978293 zobellia_2051 Zobellia galactanivorans cysteine endopeptidase, family c45 YP_004736490.1 2389483 R 63186 CDS YP_004736491.1 340618038 10974890 complement(2391209..2392090) 1 NC_015844.1 Putative transcription factor that contains a JmjC domain (jumonji family of transcription factors). JmJC domains are predicted to be metalloenzymes that adopt the cupin fold; Localized in the cytoplasm; hypothetical protein 2392090 10974890 zobellia_2052 Zobellia galactanivorans hypothetical protein YP_004736491.1 2391209 R 63186 CDS YP_004736492.1 340618039 10974891 complement(2392090..2393637) 1 NC_015844.1 Flavin containing amine oxidoreductase which contains a N-terminal DAO (D-amino acid oxidase) domain and one tranmembrane segment; Use FAD as cofactor; Belongs to the carotenoid/retinoid oxidoreductase family; Localized in the cytoplasmic membrane; Function unclear; flavin containing amine oxidoreductase 2393637 10974891 zobellia_2053 Zobellia galactanivorans flavin containing amine oxidoreductase YP_004736492.1 2392090 R 63186 CDS YP_004736493.1 340618040 10974892 complement(2393637..2397323) 1 NC_015844.1 This protein encompasses a N-terminal conserved domain predicted to be an exporter containing 13 transmembrane helices (residues 1-809) and a C-terminal catalytic domain belonging to the phospholipid/glycerol acyltransferase family (810-1228); Localized in the cytoplasmic membrane; Function unclear; exporter / acyltransferase 2397323 10974892 zobellia_2054 Zobellia galactanivorans exporter / acyltransferase YP_004736493.1 2393637 R 63186 CDS YP_004736494.1 340618041 10974893 complement(2397316..2398518) 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases., Features four transmembrane helices in C-terminus. Localized in the cytoplasmic membrane.,; Specificity unclear; glycosyltransferase 2398518 10974893 zobellia_2055 Zobellia galactanivorans glycosyltransferase YP_004736494.1 2397316 R 63186 CDS YP_004736495.1 340618042 10974894 complement(2398578..2399081) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 17 and 18; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2399081 10974894 zobellia_2056 Zobellia galactanivorans periplasmic protein YP_004736495.1 2398578 R 63186 CDS YP_004736496.1 340618043 10974895 complement(2399087..2399455) 1 NC_015844.1 (3R)-Hydroxymyristoyl-[acyl-carrier-protein] dehydratase (FabZ) catalyses the dehydratation of beta-hydroxyacyl-ACP generated by FabG to trans-2-enoyl-ACP. This is the third step of the fatty acid elongation cycle. FabZ forms a hexamer (a trimer of dimers) where the monomer adopts a beta + alpha \\hotdog\\ fold; Localized in the cytoplasm; High confidence in function and specificity; (3R)-hydroxymyristoyl-ACP dehydratase 2399455 fabZ1 10974895 fabZ1 Zobellia galactanivorans (3R)-hydroxymyristoyl-ACP dehydratase YP_004736496.1 2399087 R 63186 CDS YP_004736497.1 340618044 10977809 complement(2399461..2400048) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2400048 10977809 zobellia_2058 Zobellia galactanivorans periplasmic protein YP_004736497.1 2399461 R 63186 CDS YP_004736498.1 340618045 10974896 complement(2400045..2400656) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the outer membrane; Conserved hypothetical protein; hypothetical protein 2400656 10974896 zobellia_2059 Zobellia galactanivorans hypothetical protein YP_004736498.1 2400045 R 63186 CDS YP_004736499.1 340618046 10974897 complement(2400637..2401254) 1 NC_015844.1 LolA is a molecular chaperone that participates in the translocation of lipoproteins from the cytoplasmic membrane to the outer membrane. LolA forms a complex with lipoproteins that do not possess an aspartate residue after the N-terminal Cys residue; Contains a signal peptide cleaved between residues 17 and 18; Localized in the periplasmic space; High confidence in function and specificity; outer-membrane lipoprotein carrier protein 2401254 lolA 10974897 lolA Zobellia galactanivorans outer-membrane lipoprotein carrier protein YP_004736499.1 2400637 R 63186 CDS YP_004736500.1 340618047 10978097 complement(2401247..2402023) 1 NC_015844.1 The peptidoglycan N-acetylglucosamine deacetylase hydrolyzes the acetyl group of N-acetylglucosamine in peptidoglycans; Belongs to the family 4 of carbohydrate esterases (CE4) and fold into a 7-stranded beta/alpha barrel; Contains two N-terminal transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; peptidoglycan N-acetylglucosamine deacetylase 2402023 pgdA 10978097 pgdA Zobellia galactanivorans peptidoglycan N-acetylglucosamine deacetylase YP_004736500.1 2401247 R 63186 CDS YP_004736501.1 340618048 10978335 complement(2402017..2403081) 1 NC_015844.1 3-oxoacyl-[acyl-carrier-protein] synthase II, also known as beta-ketoacyl synthase II, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. FabF Has a preference for short chain acid substrates; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP synthase II 2403081 fabF 10978335 fabF Zobellia galactanivorans 3-oxoacyl-ACP synthase II YP_004736501.1 2402017 R 63186 CDS YP_004736502.1 340618049 10977801 complement(2403081..2404283) 1 NC_015844.1 3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP synthase 2404283 fabB3 10977801 fabB3 Zobellia galactanivorans 3-oxoacyl-ACP synthase YP_004736502.1 2403081 R 63186 CDS YP_004736503.1 340618050 10977795 complement(2404406..2404663) 1 NC_015844.1 Acyl carrier protein (ACP) is the carrier of the growing fatty acid chain in fatty acid biosynthesis. ACP is produced as an apoprotein and is converted to its active form by [ACP]synthase (AcpS); Localized in the cytoplasm; High confidence in function and specificity; acyl carrier protein 2404663 acpP2 10977795 acpP2 Zobellia galactanivorans acyl carrier protein YP_004736503.1 2404406 R 63186 CDS YP_004736504.1 340618051 10977466 complement(2404660..2405268) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2405268 10977466 zobellia_2065 Zobellia galactanivorans hypothetical protein YP_004736504.1 2404660 R 63186 CDS YP_004736505.1 340618052 10974899 complement(2405265..2406413) 1 NC_015844.1 3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP synthase 2406413 fabB4 10974899 fabB4 Zobellia galactanivorans 3-oxoacyl-ACP synthase YP_004736505.1 2405265 R 63186 CDS YP_004736506.1 340618053 10977796 complement(2406406..2406843) 1 NC_015844.1 Acyl-CoA thioester hydrolase is involved in fatty acid biosynthesis catalyzing the hydrolysis of the thioester bond in acyl-CoA to give the corresponding fatty acid and CoA; Localized in the cytoplasm; High confidence in function and specificity; acyl-CoA thioester hydrolase 2406843 ybgC1 10977796 ybgC1 Zobellia galactanivorans acyl-CoA thioester hydrolase YP_004736506.1 2406406 R 63186 CDS YP_004736507.1 340618054 10978773 complement(2406833..2408101) 1 NC_015844.1 ABC-2 Type (ATP-binding cassette) transporter membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 2408101 10978773 zobellia_2068 Zobellia galactanivorans ABC transporter permease YP_004736507.1 2406833 R 63186 CDS YP_004736508.1 340618055 10974900 complement(2408094..2408837) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; Family membership; ABC transporter ATPase 2408837 10974900 zobellia_2069 Zobellia galactanivorans ABC transporter ATPase YP_004736508.1 2408094 R 63186 CDS YP_004736509.1 340618056 10974901 complement(2408912..2409907) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2409907 10974901 zobellia_2070 Zobellia galactanivorans hypothetical protein YP_004736509.1 2408912 R 63186 CDS YP_004736510.1 340618057 10974903 complement(2409916..2410314) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2410314 10974903 zobellia_2071 Zobellia galactanivorans hypothetical protein YP_004736510.1 2409916 R 63186 CDS YP_004736511.1 340618058 10974904 complement(2410351..2410749) 1 NC_015844.1 Conserved hypothetical protein distantly related to (3R)-Hydroxymyristoyl-[acyl-carrier-protein] dehydratase (FabZ); Localized in the cytoplasm; hypothetical protein 2410749 10974904 zobellia_2072 Zobellia galactanivorans hypothetical protein YP_004736511.1 2410351 R 63186 CDS YP_004736512.1 340618059 10974905 complement(2410805..2411242) 1 NC_015844.1 (3R)-Hydroxymyristoyl-[acyl-carrier-protein] dehydratase (FabZ) catalyses the dehydratation of beta-hydroxyacyl-ACP generated by FabG to trans-2-enoyl-ACP. This is the third step of the fatty acid elongation cycle. FabZ forms a hexamer (a trimer of dimers) where the monomer adopts a beta + alpha \\hotdog\\ fold; Localized in the cytoplasm; High confidence in function and specificity; (3R)-hydroxymyristoyl-ACP dehydratase 2411242 fabZ2 10974905 fabZ2 Zobellia galactanivorans (3R)-hydroxymyristoyl-ACP dehydratase YP_004736512.1 2410805 R 63186 CDS YP_004736513.1 340618060 10977810 complement(2411244..2412377) 1 NC_015844.1 DarB is homologous to 3-oxoacyl-[acyl-carrier-protein] synthase III, also known as beta-ketoacyl-ACP synthase III (FabH), which catalyses the first condensation step within the fatty acid synthesis pathway converting the Acyl-[acyl-carrier-protein] to 3-oxoacyl-[acyl-carrier-protein]; Localized in the cytoplasm; Specificity unclear; 3-oxoacyl-ACP synthase III 2412377 darB 10977810 darB Zobellia galactanivorans 3-oxoacyl-ACP synthase III YP_004736513.1 2411244 R 63186 CDS YP_004736514.1 340618061 10977720 complement(2412387..2413310) 1 NC_015844.1 DarA catalyzes the head-to-head condensation of two beta-ketoacyl thioester intermediates (fatty acid-derived precursors) forming a dioxocyclohexene intermediate; Contains a C-terminal transmembrane helix; Localized in the cytoplasmic membrane; High confidence in function and specificity; dialkylrecorsinol condensing protein 2413310 darA 10977720 darA Zobellia galactanivorans dialkylrecorsinol condensing protein YP_004736514.1 2412387 R 63186 CDS YP_004736515.1 340618062 10977719 complement(2413382..2414269) 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Specificity unclear; acyltransferase 2414269 10977719 zobellia_2076 Zobellia galactanivorans acyltransferase YP_004736515.1 2413382 R 63186 CDS YP_004736516.1 340618063 10974906 complement(2414293..2414541) 1 NC_015844.1 Acyl carrier protein (ACP) is the carrier of the growing fatty acid chain in fatty acid biosynthesis. ACP is produced as an apoprotein and is converted to its active form by [ACP]synthase (AcpS); Localized in the cytoplasm; High confidence in function and specificity; acyl carrier protein 2414541 acpP3 10974906 acpP3 Zobellia galactanivorans acyl carrier protein YP_004736516.1 2414293 R 63186 CDS YP_004736517.1 340618064 10977467 complement(2414548..2415765) 1 NC_015844.1 3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP synthase 2415765 fabB5 10977467 fabB5 Zobellia galactanivorans 3-oxoacyl-ACP synthase YP_004736517.1 2414548 R 63186 CDS YP_004736518.1 340618065 10977797 complement(2415783..2416538) 1 NC_015844.1 FabG catalyzes the first reduction step of the fatty acid biosynthesis pathway. Belongs to the short- chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP reductase 2416538 fabG2 10977797 fabG2 Zobellia galactanivorans 3-oxoacyl-ACP reductase YP_004736518.1 2415783 R 63186 CDS YP_004736519.1 340618066 10977803 complement(2416648..2417775) 1 NC_015844.1 This conserved hypothetical protein contains KGW repeats; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; KGW repeat-containing protein 2417775 10977803 zobellia_2080 Zobellia galactanivorans KGW repeat-containing protein YP_004736519.1 2416648 R 63186 CDS YP_004736520.1 340618067 10974907 complement(2417772..2419310) 1 NC_015844.1 Histidine ammonia-lyase converts L-histidine to urocanate and ammonia. This is the first step of the histidine degradation pathway. The active site is 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly; Localized in the cytoplasm; High confidence in function and specificity; histidine ammonia-lyase 2419310 hutH 10974907 hutH Zobellia galactanivorans histidine ammonia-lyase YP_004736520.1 2417772 R 63186 CDS YP_004736521.1 340618068 10978005 2419519..2420775 1 NC_015844.1 Aromatic-ring hydroxylases (or monooxygenases) catalyze the incorporation of one atom of dioxygen into an aromatic compound and the reduction of the other oxygen atom to water. These oxidoreductases are FAD-dependent and adopt a Rossmann fold; Localized in the cytoplasm; Specificity unclear; aromatic-ring hydroxylase 2420775 10978005 zobellia_2082 Zobellia galactanivorans aromatic-ring hydroxylase YP_004736521.1 2419519 D 63186 CDS YP_004736522.1 340618069 10974908 2421111..2422124 1 NC_015844.1 Transcriptional regulator involved in the repression and/or the positive regulation of genes encoding for enzymes; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcriptional regulators, involved in the binding of the protein to the operator sequences in the DNA. At the C-terminus there is an effector- binding/oligomerisation domain; Localized in the cytoplasm; Specificity unclear; GntR family transcriptional regulator 2422124 10974908 zobellia_2083 Zobellia galactanivorans GntR family transcriptional regulator YP_004736522.1 2421111 D 63186 CDS YP_004736523.1 340618070 10974909 2422503..2425598 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations. Contains a carboxypeptidase regulatory domain (33-106) and the Plug module (122-244) acting as a channel gate. The signal peptide is cleaved between the residues 31 and 32.; Family membership; TonB-dependent Receptor 2425598 10974909 zobellia_2084 Zobellia galactanivorans TonB-dependent Receptor YP_004736523.1 2422503 D 63186 CDS YP_004736524.1 340618071 10974910 2425638..2427164 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 16 and 17; Putatively localized in the outer membrane but the determination of the membrane identity for the protein localization is not clear; it is possible that this protein be localized in both membranes; Family membership; SusD/RagB family lipoprotein 2427164 10974910 zobellia_2085 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736524.1 2425638 D 63186 CDS YP_004736525.1 340618072 10974911 2427279..2430815 1 NC_015844.1 ASPIC and UnbV sequences are found associated with tetratrico peptide repeat in several paralogous proteins in Rhodopirellula baltica and with FG-GAP repeats in several eukaryotic integrin-like proteins and in several other bacterial proteins. The FG-GAP repeat has been predicted to fold into a beta propeller structure. The FG- GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding; Contains a signal peptide of lipoprotein cleaved between the residues 24 and 25; Protein putatively localized in the cytoplasmic membrane; Function unclear; ASPIC/UnbV-like protein 2430815 10974911 zobellia_2086 Zobellia galactanivorans ASPIC/UnbV-like protein YP_004736525.1 2427279 D 63186 CDS YP_004736526.1 340618073 10974912 2430812..2434321 1 NC_015844.1 ASPIC and UnbV sequences are found associated with tetratrico peptide repeat in several paralogous proteins in Rhodopirellula baltica and with FG-GAP repeats in several eukaryotic integrin-like proteins and in several other bacterial proteins; The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding; The FG-GAP repeat has been predicted to fold into a beta propeller structure; Contains a signal peptide of lipoprotein cleaved between the residues 19 and 20; Protein putatively localized in the cytoplasmic membrane; Function unclear; ASPIC/UnbV-like protein 2434321 10974912 zobellia_2087 Zobellia galactanivorans ASPIC/UnbV-like protein YP_004736526.1 2430812 D 63186 CDS YP_004736527.1 340618074 10974913 2434305..2435630 1 NC_015844.1 Vanadium-dependent Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen peroxide forming dioxygen. They are likely to participate in the biosynthesis of halogenated natural products, such as volatile halogenated hydrocarbons, chiral halogenated terpenes, acetogenins and indoles; Lipoprotein signal peptide cleaved between the residues 17 and 18; localized in the outer membrane; Specificity unclear; vanadium-dependent haloperoxidase 2435630 10974913 zobellia_2088 Zobellia galactanivorans vanadium-dependent haloperoxidase YP_004736527.1 2434305 D 63186 CDS YP_004736528.1 340618075 10974914 2436080..2437852 1 NC_015844.1 This conserved protein belongs to the (Trans)glycosidase superfamily, which is included in the TIM beta/alpha-barrel fold. Distantly related to the glycoside hydrolases 36 (GH36); Localized in the cytoplasm; Family membership; (trans)glycosidase superfamily protein 2437852 10974914 zobellia_2089 Zobellia galactanivorans (trans)glycosidase superfamily protein YP_004736528.1 2436080 D 63186 CDS YP_004736529.1 340618076 10974915 2437860..2438420 1 NC_015844.1 Maltose O-acetyltransferase converts the maltose to acetyl-maltose from acetyl-CoA. Maltose O-acetyltransferase is a homodimer, responsible for exit of maltose and glucose in their acetylated forms; Localized in the cytoplasm; High confidence in function and specificity; maltose O-acetyltransferase 2438420 maaA1 10974915 maaA1 Zobellia galactanivorans maltose O-acetyltransferase YP_004736529.1 2437860 D 63186 CDS YP_004736530.1 340618077 10978114 2438464..2440113 1 NC_015844.1 Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains fourteen transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sodium/solute symporter 2440113 10978114 zobellia_2091 Zobellia galactanivorans sodium/solute symporter YP_004736530.1 2438464 D 63186 CDS YP_004736531.1 340618078 10974917 complement(2440125..2440958) 1 NC_015844.1 This enzyme belongs to the Acid phosphatase / vanadium-dependent haloperoxidase family protein; Features a signal peptide cleaved between residues 18 and 19; Localized in the periplasmic space; Family membership; acid phosphatase/vanadium-dependent haloperoxidase family protein 2440958 10974917 zobellia_2092 Zobellia galactanivorans acid phosphatase/vanadium-dependent haloperoxidase family protein YP_004736531.1 2440125 R 63186 CDS YP_004736532.1 340618079 10974918 complement(2441137..2442039) 1 NC_015844.1 Deacetylase. Belongs to the histone deacetylase family.; Specificity unclear; histone deacetylase family 2442039 10974918 zobellia_2093 Zobellia galactanivorans histone deacetylase family YP_004736532.1 2441137 R 63186 CDS YP_004736533.1 340618080 10974919 2442183..2442344 1 NC_015844.1 Hypothetical protein; hypothetical protein 2442344 10974919 zobellia_2094 Zobellia galactanivorans hypothetical protein YP_004736533.1 2442183 D 63186 CDS YP_004736534.1 340618081 10974920 2442376..2442528 1 NC_015844.1 Hypothetical protein; hypothetical protein 2442528 10974920 zobellia_2095 Zobellia galactanivorans hypothetical protein YP_004736534.1 2442376 D 63186 CDS YP_004736535.1 340618082 10974921 complement(2442554..2444677) 1 NC_015844.1 The protein Tex is a transcriptional accessory protein, but its exact function is not known. Contains a central RNAse H-like domain and a C-terminal S1 RNA binding domain; Localized in the cytoplasm; High confidence in function and specificity; transcriptional accessory protein Tex 2444677 texA 10974921 texA Zobellia galactanivorans transcriptional accessory protein Tex YP_004736535.1 2442554 R 63186 CDS YP_004736536.1 340618083 10978646 complement(2444742..2446820) 1 NC_015844.1 Methionyl-tRNA synthetase catalyzes the attachment of methionine to its cognate transfer RNA molecule (tRNA(Met)) in a highly specific two-step reaction. MetG is required not only for elongation of protein synthesis but also for the initiationof translation of all mRNA through initiator tRNA(fMet) aminoacylation. MetG is a homodimer that binds one zinc ion per subunit; Contains a C-terminal tRNA binding domain; Belongs to the Class Ia aminoacyl-tRNA synthetases; Localized in the cytoplasm; High confidence in function and specificity; methionyl-tRNA synthetase, class Ia 2446820 metG 10978646 metG Zobellia galactanivorans methionyl-tRNA synthetase, class Ia YP_004736536.1 2444742 R 63186 CDS YP_004736537.1 340618084 10978151 2446956..2447054 1 NC_015844.1 Hypothetical protein; hypothetical protein 2447054 10978151 zobellia_2098 Zobellia galactanivorans hypothetical protein YP_004736537.1 2446956 D 63186 CDS YP_004736538.1 340618085 10974922 complement(2447090..2448799) 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF1501 family; Contains a twin-arginine translocation signal peptide; Localized in the periplasmic space; hypothetical protein 2448799 10974922 zobellia_2099 Zobellia galactanivorans hypothetical protein YP_004736538.1 2447090 R 63186 CDS YP_004736539.1 340618086 10974923 complement(2448811..2450304) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2450304 10974923 zobellia_2100 Zobellia galactanivorans hypothetical protein YP_004736539.1 2448811 R 63186 CDS YP_004736540.1 340618087 10974926 2450500..2450859 1 NC_015844.1 Conserved hypothetical protein belonging to the UPF0102 family. localized in the cytoplasm; hypothetical protein 2450859 10974926 zobellia_2101 Zobellia galactanivorans hypothetical protein YP_004736540.1 2450500 D 63186 CDS YP_004736541.1 340618088 10974927 2450975..2451670 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2451670 10974927 zobellia_2102 Zobellia galactanivorans hypothetical protein YP_004736541.1 2450975 D 63186 CDS YP_004736542.1 340618089 10974928 complement(2451676..2452995) 1 NC_015844.1 Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Contains a N-terminal domain of unknown function and a C-terminal Thiol-disulfide oxidoreductase domain; Belongs to the thioredoxin family; Signal peptide cleaved between residues 18 and 19; Localized in the periplasmic space; Specificity unclear; thiol-disulfide oxidoreductase 2452995 10974928 zobellia_2103 Zobellia galactanivorans thiol-disulfide oxidoreductase YP_004736542.1 2451676 R 63186 CDS YP_004736543.1 340618090 10974929 complement(2453048..2454973) 1 NC_015844.1 alpha-Amino acid ester hydrolases (AEHs) catalyze the hydrolysis and synthesis of esters and amides with an alpha-amino group. They can synthesize beta-lactam antibiotics from acyl compounds and beta-lactam nuclei obtained from the hydrolysis of natural antibiotics. Belongs to the family S15 of the peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 14 and 15; Localized in the outer membrane; Specificity unclear; alpha-amino acid ester hydrolase 2454973 aehA 10974929 aehA Zobellia galactanivorans alpha-amino acid ester hydrolase YP_004736543.1 2453048 R 63186 CDS YP_004736544.1 340618091 10977475 complement(2455026..2456318) 1 NC_015844.1 Acetyl xylan esterase catalyzes the hydrolysis of acetyl groups of xylan; Contains a signal peptide cleaved between the residues 21 and 22; Belongs to the family 7 of carbohydrate esterases (CE7); Localized in the periplasmic space; High confidence in function and specificity; acetyl xylan esterase, family CE7 2456318 axeA 10977475 axeA Zobellia galactanivorans acetyl xylan esterase, family CE7 YP_004736544.1 2455026 R 63186 CDS YP_004736545.1 340618092 10977583 complement(2456405..2459809) 1 NC_015844.1 The transcription-repair coupling factor (TRCF) acts as an ATP-dependent helicase that is necessary for strand-specific repair. A lesion in the template strand blocks the RNA polymerase (RNAP). The RNAP-DNA-RNA complex is specifically recognized by TRCF which releases RNAP and the unfinished transcript. The TCRF may replace RNAP at the lesion site and then recruit the UvrABC repair system; Belongs to the superfamily 2 of helicases; Localized in the cytoplasm; High confidence in function and specificity; transcription-repair coupling factor 2459809 mfdA 10977583 mfdA Zobellia galactanivorans transcription-repair coupling factor YP_004736545.1 2456405 R 63186 CDS YP_004736546.1 340618093 10978158 2460105..2461454 1 NC_015844.1 Glutathione reductase maintains high levels of reduced glutathione in the cytosol; Its active site is a redox-active disulfide bond; Glutathione reductase is a homodimer which binds 1 NADP and 1 FAD per subunit; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family; Localized in the cytoplasm; High confidence in function and specificity; glutathione reductase 2461454 gorA 10978158 gorA Zobellia galactanivorans glutathione reductase YP_004736546.1 2460105 D 63186 CDS YP_004736547.1 340618094 10977946 complement(2461471..2462271) 1 NC_015844.1 Contains eight transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2462271 10977946 zobellia_2108 Zobellia galactanivorans membrane protein YP_004736547.1 2461471 R 63186 CDS YP_004736548.1 340618095 10974930 complement(2462343..2462930) 1 NC_015844.1 The metallo-phosphoesterase motif is found in a large number of proteins invoved in phosphoryation. These include serine/threonine phosphatases, DNA polymerase, exonucleases, and other phosphatases; Localized in the cytoplasm; Family membership; metallophosphoesterase family protein 2462930 10974930 zobellia_2109 Zobellia galactanivorans metallophosphoesterase family protein YP_004736548.1 2462343 R 63186 CDS YP_004736549.1 340618096 10974931 complement(2463108..2467448) 1 NC_015844.1 Endonuclease/exonuclease/phosphatase family protein; Contains an OB-fold nucleic acid binding domain and an endonuclease/phosphatase domain; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Family membership; endonuclease / exonuclease / phosphatase family protein 2467448 10974931 zobellia_2110 Zobellia galactanivorans endonuclease / exonuclease / phosphatase family protein YP_004736549.1 2463108 R 63186 CDS YP_004736550.1 340618097 10974933 2467794..2468234 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Hypothetical protein; hypothetical protein 2468234 10974933 zobellia_2111 Zobellia galactanivorans hypothetical protein YP_004736550.1 2467794 D 63186 CDS YP_004736551.1 340618098 10974934 complement(2468323..2470791) 1 NC_015844.1 Contains the motif DExD/H found in ATP-dependent helicases as well as a number of hypothetical proteins together with the helicase conserved C-terminal domain; Belongs to the helicase family; Localized in the cytoplasm; Specificity unclear; ATP-dependent helicase 2470791 10974934 zobellia_2112 Zobellia galactanivorans ATP-dependent helicase YP_004736551.1 2468323 R 63186 CDS YP_004736552.1 340618099 10974935 complement(2470799..2472463) 1 NC_015844.1 DNA ligase (polydeoxyribonucleotide synthase) joins two DNA fragments by catalysing the formation of an internucleotide phosphodiester bond between 5-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using ATP as a coenzyme and as the energy source. It is essential for DNA replication, DNA recombination and DNA repair; Belongs to the ATP-dependent DNA ligase family; Localized in the cytoplasm; High confidence in function and specificity; DNA ligase 2472463 ligC 10974935 ligC Zobellia galactanivorans DNA ligase YP_004736552.1 2470799 R 63186 CDS YP_004736553.1 340618100 10978091 complement(2472460..2473500) 1 NC_015844.1 Protein belonging to the zinc-dependent beta-lactamase superfamily. The active site is characterized by several conserved histidines binding the catalytic zinc ions. The enzymes can bind one or two zinc ions; Localized in the cytoplasm; Specificity unclear; metallo-beta-lactamase superfamily protein 2473500 10978091 zobellia_2114 Zobellia galactanivorans metallo-beta-lactamase superfamily protein YP_004736553.1 2472460 R 63186 CDS YP_004736554.1 340618101 10974936 2473642..2474064 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2474064 10974936 zobellia_2115 Zobellia galactanivorans hypothetical protein YP_004736554.1 2473642 D 63186 CDS YP_004736555.1 340618102 10974937 complement(2474117..2475127) 1 NC_015844.1 Fructose-1,6-bisphosphatase is involved in glycolysis / gluconeogenesis and in mannose and fructose metabolism. It removes one phosphate group from D-fructose 1,6-bisphosphate to form D-fructose 6-phosphate. The catalytic mechanism of FbpA is dependent of Mg2+; Belongs to the inositol polyphosphate 1 phosphatase like superfamily; Localized in the cytoplasm; High confidence in function and specificity; fructose-1,6-bisphosphatase 2475127 fbpA 10974937 fbpA Zobellia galactanivorans fructose-1,6-bisphosphatase YP_004736555.1 2474117 R 63186 CDS YP_004736556.1 340618103 10977819 2475244..2475723 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 2475723 10977819 zobellia_2117 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004736556.1 2475244 D 63186 CDS YP_004736557.1 340618104 10974938 2475733..2476068 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2476068 10974938 zobellia_2118 Zobellia galactanivorans hypothetical protein YP_004736557.1 2475733 D 63186 CDS YP_004736558.1 340618105 10974939 2476113..2477363 1 NC_015844.1 Aspartate kinase III is involved in L-Lysine biosynthesis pathways. It converts L-aspartate to 4-phospho-L-aspartate; Belongs to the Amino acid kinase family; Localized in the cytoplasm; High confidence in function and specificity; aspartate kinase III 2477363 lysC 10974939 lysC Zobellia galactanivorans aspartate kinase III YP_004736558.1 2476113 D 63186 CDS YP_004736559.1 340618106 10978112 2477453..2479264 1 NC_015844.1 Contains an N-terminal Phospholipid/glycerol Acyltransferase domain and a C-terminal hemolysin domain; Localized in the cytoplasm; Family membership; phospholipid/glycerol acyltransferase / hemolysin fusion 2479264 10978112 zobellia_2120 Zobellia galactanivorans phospholipid/glycerol acyltransferase / hemolysin fusion YP_004736559.1 2477453 D 63186 CDS YP_004736560.1 340618107 10974941 complement(2479281..2479781) 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 2479781 10974941 zobellia_2121 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004736560.1 2479281 R 63186 CDS YP_004736561.1 340618108 10974942 complement(2479807..2480205) 1 NC_015844.1 Contains two transmembrane segments; Localized in the cytoplasmic membrane; hypothetical protein 2480205 10974942 zobellia_2122 Zobellia galactanivorans hypothetical protein YP_004736561.1 2479807 R 63186 CDS YP_004736562.1 340618109 10974943 complement(2480368..2480835) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2480835 10974943 zobellia_2123 Zobellia galactanivorans hypothetical protein YP_004736562.1 2480368 R 63186 CDS YP_004736563.1 340618110 10974944 complement(2480835..2481206) 1 NC_015844.1 Protein belonging to the Glyoxalase (lactoylglutathione lyase) superfamily protein; Localized in the cytoplasm; Family membership; glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2481206 10974944 zobellia_2124 Zobellia galactanivorans glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004736563.1 2480835 R 63186 CDS YP_004736564.1 340618111 10974945 complement(2481290..2482270) 1 NC_015844.1 NAD-dependent 2-hydroxyacid dehydrogenase which seems to be specific for the D-isomer of their substrate; Contains a NAD-binding domain; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family; Localized in the cytoplasm; Specificity unclear; d-isomer specific 2-hydroxyacid dehydrogenase 2482270 10974945 zobellia_2125 Zobellia galactanivorans d-isomer specific 2-hydroxyacid dehydrogenase YP_004736564.1 2481290 R 63186 CDS YP_004736565.1 340618112 10974946 complement(2482450..2483802) 1 NC_015844.1 Divalent cation transporter belonging to the MgtE family; Contains five transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; divalent cation transporter 2483802 10974946 zobellia_2126 Zobellia galactanivorans divalent cation transporter YP_004736565.1 2482450 R 63186 CDS YP_004736566.1 340618113 10974947 complement(2483972..2484835) 1 NC_015844.1 The 16S rRNA adenine dimethyltransferase specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'end of 16S rRNA in the 30S particle. Its inactivation leads to kasugamycin resistance; Localized in the cytoplasm; High confidence in function and specificity; 16S rRNA adenine dimethyltransferase 2484835 ksgA 10974947 ksgA Zobellia galactanivorans 16S rRNA adenine dimethyltransferase YP_004736566.1 2483972 R 63186 CDS YP_004736567.1 340618114 10978069 complement(2484845..2485147) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2485147 10978069 zobellia_2128 Zobellia galactanivorans hypothetical protein YP_004736567.1 2484845 R 63186 CDS YP_004736568.1 340618115 10974948 complement(2485167..2485478) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2485478 10974948 zobellia_2129 Zobellia galactanivorans hypothetical protein YP_004736568.1 2485167 R 63186 CDS YP_004736569.1 340618116 10974949 complement(2485488..2487152) 1 NC_015844.1 Modular protein with a N-terminal domain of unknown function, a central PDZ domain involved in protein-protein interaction and C-terminal processing peptidase. The catalytic module shows specific recognition for a C-terminal tripeptide, Ala/Leu-Ala/Tyr-Ala, but then cleaves at a variable distance from the C-terminus; belongs to the family 41 of the serine peptidases (S41); Signal peptide cleaved between the residues 20 and 21; Localized in the periplasm; High confidence in function and specificity; carboxy-terminal processing peptidase 2487152 10974949 zobellia_2130 Zobellia galactanivorans carboxy-terminal processing peptidase YP_004736569.1 2485488 R 63186 CDS YP_004736570.1 340618117 10974951 complement(2487187..2488971) 1 NC_015844.1 Protein containing six tetratrico peptide repeats (TPR). TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Function unclear; hypothetical protein 2488971 10974951 zobellia_2131 Zobellia galactanivorans hypothetical protein YP_004736570.1 2487187 R 63186 CDS YP_004736571.1 340618118 10974952 2489177..2489488 1 NC_015844.1 Hypothetical protein; hypothetical protein 2489488 10974952 zobellia_2132 Zobellia galactanivorans hypothetical protein YP_004736571.1 2489177 D 63186 CDS YP_004736572.1 340618119 10974953 complement(2489545..2490816) 1 NC_015844.1 Seryl-tRNA synthetase is responsible for the attachment of serine to the 3' OH group of ribose of its cognate transfer RNA molecule (tRNA(Ser)) in a highly specific two-step reaction. It is a homodimer; Belongs to the class-IIa aminoacyl-tRNA synthetase family; Localized in the cytoplasm; High confidence in function and specificity; seryl-tRNA synthetase, class IIa 2490816 serS 10974953 serS Zobellia galactanivorans seryl-tRNA synthetase, class IIa YP_004736572.1 2489545 R 63186 CDS YP_004736573.1 340618120 10978584 2490896..2491273 1 NC_015844.1 Protein belonging to the Glyoxalase superfamily protein (lactoylglutathione lyase); Localized in the cytoplasm; Family membership; glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2491273 10978584 zobellia_2134 Zobellia galactanivorans glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004736573.1 2490896 D 63186 CDS YP_004736574.1 340618121 10974954 complement(2491260..2492600) 1 NC_015844.1 Vitamin K-dependent gamma-glutamyl carboxylase is involved in the Vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues in various proteins. It converts glutamate residues to gamma-carboxyglutamate; Contains six transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; vitamin K-dependent gamma-glutamyl carboxylase 2492600 ggcX 10974954 ggcX Zobellia galactanivorans vitamin K-dependent gamma-glutamyl carboxylase YP_004736574.1 2491260 R 63186 CDS YP_004736575.1 340618122 10977893 complement(2492601..2493527) 1 NC_015844.1 Riboflavin biosynthesis protein RibF is a protein that includes a Riboflavin kinase activity and a FMN adenylyltransferase activity; Localized in the cytoplasm; High confidence in function and specificity; riboflavin biosynthesis protein RibF 2493527 ribF 10977893 ribF Zobellia galactanivorans riboflavin biosynthesis protein RibF YP_004736575.1 2492601 R 63186 CDS YP_004736576.1 340618123 10978463 2493580..2497365 1 NC_015844.1 Endopeptidase Containing a large C-terminal region, encompassing a fibronectin type 3 domain and a proprotein convertase P-domain necessary for folding and maintaining the endopeptidase catalytic domain and to regulate its calcium and acidic pH dependence; Belongs to the family 12 of the metallopeptidases (M12); Signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Specificity unclear; metalloendopeptidase 2 2497365 10978463 zobellia_2137 Zobellia galactanivorans metalloendopeptidase 2 YP_004736576.1 2493580 D 63186 CDS YP_004736577.1 340618124 10974955 2497362..2498042 1 NC_015844.1 Protein that contains two type-III fibronectin (FN3) domains. Structures of individual FN3 domains have revealed a conserved beta sandwich fold also found in bacterial glycosyde hydrolases and other proteins; Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Function unclear; fibronectin type-III repeat-containing protein 2498042 10974955 zobellia_2138 Zobellia galactanivorans fibronectin type-III repeat-containing protein YP_004736577.1 2497362 D 63186 CDS YP_004736578.1 340618125 10974956 complement(2498029..2498658) 1 NC_015844.1 Peptidyl-tRNA hydrolase hyrolyzes the N-substituted aminoacyl-tRNA to N-substituted amino acid and tRNA. The natural substrate for this enzyme may be the peptidyl-tRNAs which drop off the ribosome during protein synthesis; Localized in the cytoplasm; High confidence in function and specificity; peptidyl-tRNA hydrolase 2498658 pthA 10974956 pthA Zobellia galactanivorans peptidyl-tRNA hydrolase YP_004736578.1 2498029 R 63186 CDS YP_004736579.1 340618126 10978395 complement(2498779..2499408) 1 NC_015844.1 Ribosomal protein L25 is a part of the large ribosomal subunit (50S). This is one of the proteins that binds to the 5S rRNA where it forms part of the central protuberance. It binds to the 5S rRNA independently of L5 and L18. Not required for binding of the 5S rRNA/L5/L18 subcomplex to 23S rRNA; Belongs to the ribosomal protein L25p family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L25 2499408 rplY 10978395 rplY Zobellia galactanivorans 50S ribosomal protein L25 YP_004736579.1 2498779 R 63186 CDS YP_004736580.1 340618127 10978515 complement(2499455..2500396) 1 NC_015844.1 Ribose-phosphate pyrophosphokinase converts the D-ribose 5-phosphate to 5-phospho-alpha-D-ribose 1-diphosphate in the Pentose phosphate pathway. Utilized by both the de novo and the salvage pathways by which endogenously formed or exogenously added pyrimidine, purine, or pyridine bases are converted to the corresponding ribonucleoside monophosphates; Localized in the cytoplasm; High confidence in function and specificity; ribose-phosphate pyrophosphokinase 2500396 prsA 10978515 prsA Zobellia galactanivorans ribose-phosphate pyrophosphokinase YP_004736580.1 2499455 R 63186 CDS YP_004736581.1 340618128 10974033 2500797..2501063 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2501063 10974033 zobellia_2143 Zobellia galactanivorans hypothetical protein YP_004736581.1 2500797 D 63186 CDS YP_004736582.1 340618129 10974958 2501300..2504377 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (49-123) and the Plug module (139-247) acting as a channel gate; The signal peptide is cleaved between the residues 23 and 24; Family membership; TonB-dependent Receptor 2504377 10974958 zobellia_2144 Zobellia galactanivorans TonB-dependent Receptor YP_004736582.1 2501300 D 63186 CDS YP_004736583.1 340618130 10974959 2504381..2505835 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the cytoplasmic membrane; Family membership; SusD/RagB family lipoprotein 2505835 10974959 zobellia_2145 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736583.1 2504381 D 63186 CDS YP_004736584.1 340618131 10974960 complement(2505916..2507019) 1 NC_015844.1 Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2507019 10974960 zobellia_2146 Zobellia galactanivorans membrane protein YP_004736584.1 2505916 R 63186 CDS YP_004736585.1 340618132 10974961 complement(2507033..2508841) 1 NC_015844.1 Modular protein that consists of a N-terminal conserved domain of unknown function (240 residues) and a C-terminal Alkaline phosphatase domain; Signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Specificity unclear; alkaline phosphatase 2508841 phoB 10974961 phoB Zobellia galactanivorans alkaline phosphatase YP_004736585.1 2507033 R 63186 CDS YP_004736586.1 340618133 10978346 complement(2508921..2510510) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 2510510 10978346 zobellia_2148 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736586.1 2508921 R 63186 CDS YP_004736587.1 340618134 10974962 complement(2510532..2513597) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (22-98) and the Plug module (117-220) acting as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 2513597 10974962 zobellia_2149 Zobellia galactanivorans TonB-dependent Receptor YP_004736587.1 2510532 R 63186 CDS YP_004736588.1 340618135 10974963 complement(2513776..2517507) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of an unknown function domain and a C-terminal AraC-type HTH domain; The periplasmic and cytoplasmic parts are separated by a transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 2517507 10974963 zobellia_2150 Zobellia galactanivorans one-component system sensor protein YP_004736588.1 2513776 R 63186 CDS YP_004736589.1 340618136 10974965 complement(2517695..2518060) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2518060 10974965 zobellia_2151 Zobellia galactanivorans membrane protein YP_004736589.1 2517695 R 63186 CDS YP_004736590.1 340618137 10974966 complement(2518201..2518656) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 2518656 10974966 zobellia_2152 Zobellia galactanivorans hypothetical protein YP_004736590.1 2518201 R 63186 CDS YP_004736591.1 340618138 10974967 2518712..2518804 1 NC_015844.1 Hypothetical protein; hypothetical protein 2518804 10974967 zobellia_2153 Zobellia galactanivorans hypothetical protein YP_004736591.1 2518712 D 63186 CDS YP_004736592.1 340618139 10974968 2518801..2520198 1 NC_015844.1 TrmE is a 3-domain protein that controls modification of the uridine at the wobble position (U34) of tRNAs that read codons ending with A or G in the mixed codon family boxes. Exhibits a very high intrinsic GTPase hydrolysis rate; Belongs to the Era/TrmE GTP-binding protein family, TrmE subfamily; Localized in the cytoplasm; High confidence in function and specificity; tRNA modification GTPase TrmE 2520198 trmE 10974968 trmE Zobellia galactanivorans tRNA modification GTPase TrmE YP_004736592.1 2518801 D 63186 CDS YP_004736593.1 340618140 10978689 complement(2520337..2521611) 1 NC_015844.1 The Iota-carrageenases hydrolyse the 1,4-beta-D-galactosidic linkages in the iota-carrgeenan giving the tetramer as the predominant product; Belongs to the family 82 of glycoside hydrolases (GH82); Signal peptide of lipoprotein cleaved between the residues 19 and 20; Localized in the outer membrane; High confidence in function and specificity; iota-carrageenase 2521611 cgiA2 10978689 cgiA2 Zobellia galactanivorans iota-carrageenase YP_004736593.1 2520337 R 63186 CDS YP_004736594.1 340618141 10977646 2521903..2522607 1 NC_015844.1 protein that transports nickel ions with High-affinity; Contains five transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; high-affinity nickel-transport protein 2522607 10977646 zobellia_2156 Zobellia galactanivorans high-affinity nickel-transport protein YP_004736594.1 2521903 D 63186 CDS YP_004736595.1 340618142 10974969 complement(2522604..2523698) 1 NC_015844.1 Contains five NHL repeats involved in the formation of beta-propeller fold; Localized in the cytoplasm; Conserved hypothetical protein; hypothetical protein 2523698 10974969 zobellia_2157 Zobellia galactanivorans hypothetical protein YP_004736595.1 2522604 R 63186 CDS YP_004736596.1 340618143 10974970 complement(2523757..2524818) 1 NC_015844.1 HypE (or HupE) is a protein required for expression of catalytically active hydrogenase in many systems. It appears to be an accessory protein involved in maturation rather than a regulatory protein involved in expression. HypE would be part of the hyp operon (Ni-Fe hydrogenase); Localized in the cytoplasm; High confidence in function and specificity; hydrogenase expression/formation protein HypE 2524818 hypE 10974970 hypE Zobellia galactanivorans hydrogenase expression/formation protein HypE YP_004736596.1 2523757 R 63186 CDS YP_004736597.1 340618144 10978016 complement(2524952..2525512) 1 NC_015844.1 Contains a domain of unknown function (DUF) 1568; Localized in the cytoplasm; hypothetical protein 2525512 10978016 zobellia_2159 Zobellia galactanivorans hypothetical protein YP_004736597.1 2524952 R 63186 CDS YP_004736598.1 340618145 10974971 complement(2525562..2526656) 1 NC_015844.1 HypD is involved in hydrogenase formation. HypD is a part of the hyp operon (Ni-Fe hydrogenase); Contains many possible metal binding residues, which may bind to nickel; Localized in the cytoplasm; High confidence in function and specificity; hydrogenase expression/formation protein HypD 2526656 hypD 10974971 hypD Zobellia galactanivorans hydrogenase expression/formation protein HypD YP_004736598.1 2525562 R 63186 CDS YP_004736599.1 340618146 10978015 complement(2526663..2526941) 1 NC_015844.1 The hydrogenase expression/formation proteins HypC is a part of the operon (Ni-Fe hydrogenase). HypC is a hydrogenase precursor-specific chaperone required for a maturation process. They are believed to keep the hydrogenase precursor in a conformation accessible for metal incorporation in active site; Belongs to the hupF/hypC family; Localized in the cytoplasm; High confidence in function and specificity; hydrogenase expression/formation proteins HypC 2526941 hypC 10978015 hypC Zobellia galactanivorans hydrogenase expression/formation proteins HypC YP_004736599.1 2526663 R 63186 CDS YP_004736600.1 340618147 10978014 complement(2526945..2529206) 1 NC_015844.1 Along with hypE, HypF functions as a carbamoyl transferase catalyzing the synthesis of CO and CN-ligands of the active site iron of [NiFe]-hydrogenases using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of hypE yielding a protein-S-carboxamide; Forms a complex with hypE; Contains an N-terminal acylphosphatase domain, two repeats of zinc fingers and a C-terminal O-carbamoyltransferase domain; Localized in the cytoplasm; High confidence in function and specificity; carbamoyltransferase HypF 2529206 hypF 10978014 hypF Zobellia galactanivorans carbamoyltransferase HypF YP_004736600.1 2526945 R 63186 CDS YP_004736601.1 340618148 10978017 complement(2529294..2529989) 1 NC_015844.1 The hydrogenase accessory protein HypB is a part of the hyp operon (Ni-Fe hydrogenase). HypB is a GTP hydrolase for assembly of nickel metallocentre of hydrogenase. The GTP hydrolysis catalyzed is an integral process in the incorporation of nickel into hydrogenases; Belongs to the hypB/hupM family; Localized in the cytoplasm; High confidence in function and specificity; hydrogenase nickel incorporation protein HypB 2529989 hypB 10978017 hypB Zobellia galactanivorans hydrogenase nickel incorporation protein HypB YP_004736601.1 2529294 R 63186 CDS YP_004736602.1 340618149 10978013 complement(2530057..2530404) 1 NC_015844.1 Hydrogenase nickel insertion protein HybF is a part of hyp operon (Ni-Fe hydrogenase). HypA probably plays a role in an hydrogenase nickel cofactor insertion step; Contains, in its C-terminal region, four conserved cysteines that form a zinc-finger like motif; Belongs to the hypA/hybF family; Localized in the cytoplasm; High confidence in function and specificity; hydrogenase nickel incorporation protein HypA 2530404 hypA 10978013 hypA Zobellia galactanivorans hydrogenase nickel incorporation protein HypA YP_004736602.1 2530057 R 63186 CDS YP_004736603.1 340618150 10978012 complement(2530404..2531885) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2531885 10978012 zobellia_2165 Zobellia galactanivorans hypothetical protein YP_004736603.1 2530404 R 63186 CDS YP_004736604.1 340618151 10974973 complement(2531860..2532117) 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 2532117 10974973 zobellia_2166 Zobellia galactanivorans hypothetical protein YP_004736604.1 2531860 R 63186 CDS YP_004736605.1 340618152 10974974 complement(2532114..2532434) 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 2532434 10974974 zobellia_2167 Zobellia galactanivorans hypothetical protein YP_004736605.1 2532114 R 63186 CDS YP_004736606.1 340618153 10974975 complement(2532431..2532910) 1 NC_015844.1 Endopeptidase involved in the maturation of the large subunit of a specific Ni-Fe hydrogenase. The Ni-Fe hydrogenases contain the metallo centre, and once nickel has been bound in this, the subunit is processed to the active enzyme by cleavage at a conserved site near the C-terminus; Belongs to the family 31 of the aspartic peptidases (A31); Localized in the cytoplasm; High confidence in function and specificity; hydrogenase maturation protease, family A31 2532910 hyaD 10974975 hyaD Zobellia galactanivorans hydrogenase maturation protease, family A31 YP_004736606.1 2532431 R 63186 CDS YP_004736607.1 340618154 10978010 complement(2532993..2534585) 1 NC_015844.1 Ni-Fe hydrogenase, large subunit is one hydrogenase synthesized in response to different physiological conditions. Could be involved in the detoxcation process; Forms a heterodimer; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family; Localized in the cytoplasm; High confidence in function and specificity; Ni-Fe hydrogenase , large subunit 2534585 hyaB 10978010 hyaB Zobellia galactanivorans Ni-Fe hydrogenase , large subunit YP_004736607.1 2532993 R 63186 CDS YP_004736608.1 340618155 10978009 complement(2534607..2535596) 1 NC_015844.1 Ni-Fe hydrogenase, large subunit is one hydrogenase synthesized in response to different physiological conditions. Could be involved in the detoxcation process; Forms a heterodimer; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family; Localized in the cytoplasm; High confidence in function and specificity; Ni-Fe hydrogenase , small subunit 2535596 hyaA 10978009 hyaA Zobellia galactanivorans Ni-Fe hydrogenase , small subunit YP_004736608.1 2534607 R 63186 CDS YP_004736609.1 340618156 10978008 2535939..2537753 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2537753 10978008 zobellia_2171 Zobellia galactanivorans hypothetical protein YP_004736609.1 2535939 D 63186 CDS YP_004736610.1 340618157 10974977 complement(2537879..2538010) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2538010 10974977 zobellia_2172 Zobellia galactanivorans hypothetical protein YP_004736610.1 2537879 R 63186 CDS YP_004736611.1 340618158 10974978 complement(2538091..2539269) 1 NC_015844.1 Glutaryl-CoA dehydrogenase catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO2 in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism; Uses FAD as prosthetic group; Belongs to the acyl-CoA dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity; glutaryl-CoA dehydrogenase 2539269 gcdH 10974978 gcdH Zobellia galactanivorans glutaryl-CoA dehydrogenase YP_004736611.1 2538091 R 63186 CDS YP_004736612.1 340618159 10977882 complement(2539325..2540053) 1 NC_015844.1 Adenine-specific DNA methyltransferase.; High confidence in function and specificity; adenine-specific DNa methyltransferase 2540053 10977882 zobellia_2174 Zobellia galactanivorans adenine-specific DNa methyltransferase YP_004736612.1 2539325 R 63186 CDS YP_004736613.1 340618160 10974979 2540322..2541368 1 NC_015844.1 Xylose isomerase-like TIM barrel protein. Features a signal peptide cleaved between the residues 32 and 33. Localized in the periplasm.; Conserved hypothetical protein; xylose isomerase-like TIM barrel protein 2541368 10974979 zobellia_2175 Zobellia galactanivorans xylose isomerase-like TIM barrel protein YP_004736613.1 2540322 D 63186 CDS YP_004736614.1 340618161 10974980 complement(2541406..2541936) 1 NC_015844.1 Specificity unclear; 16S rRNA processing protein RimM 2541936 rimM 10974980 rimM Zobellia galactanivorans 16S rRNA processing protein RimM YP_004736614.1 2541406 R 63186 CDS YP_004736615.1 340618162 10978467 complement(2541953..2542504) 1 NC_015844.1 Ribosomal protein S16 is one of the proteins from the 30S ribosomal subunit; In addition to being a ribosomal protein, S16 also has a cation-dependent endonuclease activity; Belongs to the ribosomal protein S16p family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S16 2542504 rpsP 10978467 rpsP Zobellia galactanivorans 30S ribosomal protein S16 YP_004736615.1 2541953 R 63186 CDS YP_004736616.1 340618163 10978546 2542812..2547248 1 NC_015844.1 The alpha subunit of DNA polymerase III is responsible of the polymerase activity; Contains a N-terminal exonuclease domain, a PHP domain (phosphoesterase) and a C-terminal OB module (oligonucleotide /oligosaccharide-binding fold) involved in the DNA binding; The DNA polymerase III or replicase is responsible for most of the replicative synthesis in bacteria. It also exhibits a 3' to 5' exonuclease proofreading activity; Localized in the cytoplasm; High confidence in function and specificity; DNA polymerase III subunit alpha 2547248 dnaE1 10978546 dnaE1 Zobellia galactanivorans DNA polymerase III subunit alpha YP_004736616.1 2542812 D 63186 CDS YP_004736617.1 340618164 10977750 2547378..2547695 1 NC_015844.1 Thioredoxin is a small disulfide-containing redox protein that participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions; Localized in the cytoplasm; High confidence in function and specificity; thioredoxin 2547695 trxA 10977750 trxA Zobellia galactanivorans thioredoxin YP_004736617.1 2547378 D 63186 CDS YP_004736618.1 340618165 10978705 2547809..2548738 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 2548738 10978705 zobellia_2180 Zobellia galactanivorans hypothetical protein YP_004736618.1 2547809 D 63186 CDS YP_004736619.1 340618166 10974034 2549250..2550062 1 NC_015844.1 Deoxyribonuclease I. Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products. Features a signal peptide cleaved between the residues 18 and 19. Localized in the periplasm.; Specificity unclear; deoxyribonuclease I 2550062 10974034 zobellia_2182 Zobellia galactanivorans deoxyribonuclease I YP_004736619.1 2549250 D 63186 CDS YP_004736620.1 340618167 10974983 complement(2550172..2550390) 1 NC_015844.1 Contains a putative signal peptide cleaved between 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2550390 10974983 zobellia_2183 Zobellia galactanivorans periplasmic protein YP_004736620.1 2550172 R 63186 CDS YP_004736621.1 340618168 10974984 complement(2550377..2551429) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2551429 10974984 zobellia_2184 Zobellia galactanivorans hypothetical protein YP_004736621.1 2550377 R 63186 CDS YP_004736622.1 340618169 10974985 complement(2551491..2551646) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2551646 10974985 zobellia_2185 Zobellia galactanivorans hypothetical protein YP_004736622.1 2551491 R 63186 CDS YP_004736623.1 340618170 10974986 complement(2551903..2552124) 1 NC_015844.1 Possible cytoplasmic protein; hypothetical protein 2552124 10974986 zobellia_2186 Zobellia galactanivorans hypothetical protein YP_004736623.1 2551903 R 63186 CDS YP_004736624.1 340618171 10974987 complement(2552214..2552879) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LuxR-type HTH domain, which acts as transcriptional regulator; Family membership; two-component system-response regulator 2552879 10974987 zobellia_2187 Zobellia galactanivorans two-component system-response regulator YP_004736624.1 2552214 R 63186 CDS YP_004736625.1 340618172 10974988 complement(2552892..2554802) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP-dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal-dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains one transmembrane segment and one N-terminal tetratrico peptide motif (TPR); Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 2554802 10974988 zobellia_2188 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004736625.1 2552892 R 63186 CDS YP_004736626.1 340618173 10974989 complement(2554908..2555063) 1 NC_015844.1 Lipoprotein with a signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Hypothetical protein; hypothetical protein 2555063 10974989 zobellia_2189 Zobellia galactanivorans hypothetical protein YP_004736626.1 2554908 R 63186 CDS YP_004736627.1 340618174 10974990 2555118..2555318 1 NC_015844.1 Hypothetical protein; hypothetical protein 2555318 10974990 zobellia_2190 Zobellia galactanivorans hypothetical protein YP_004736627.1 2555118 D 63186 CDS YP_004736628.1 340618175 10974992 2555446..2556204 1 NC_015844.1 Contains one central transmembrane segment; Probably localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2556204 10974992 zobellia_2191 Zobellia galactanivorans hypothetical protein YP_004736628.1 2555446 D 63186 CDS YP_004736629.1 340618176 10974993 complement(2556229..2557734) 1 NC_015844.1 The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Lipoprotein with a signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; High confidence in function and specificity; N-sulfoglucosamine sulfohydrolase 2557734 sgsA2 10974993 sgsA2 Zobellia galactanivorans N-sulfoglucosamine sulfohydrolase YP_004736629.1 2556229 R 63186 CDS YP_004736630.1 340618177 10978587 complement(2557742..2560015) 1 NC_015844.1 Modular protein containing a N-terminal domain belonging to family 1 of sulfatases and a C-terminal gluconolactonase domain. The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates. Gluconolactonases hydrolyze the gluconolactone to gluconate; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 24; Lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the cytoplasmic and/or the outer membrane; Family membership; sulfatase 2560015 10978587 zobellia_2193 Zobellia galactanivorans sulfatase YP_004736630.1 2557742 R 63186 CDS YP_004736631.1 340618178 10974994 complement(2560055..2561539) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Putative lipoprotein signal peptide cleaved between the residues 27 and 28; Possibly localized in the outer membrane; Family membership; sulfatase 2561539 10974994 zobellia_2194 Zobellia galactanivorans sulfatase YP_004736631.1 2560055 R 63186 CDS YP_004736632.1 340618179 10974995 2561827..2564556 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (29-112) and the Plug module (125-207) acting as a channel gate; The signal peptide is cleaved between the residues 26 and 27; Specificity unclear; TonB-dependent Receptor 2564556 10974995 zobellia_2195 Zobellia galactanivorans TonB-dependent Receptor YP_004736632.1 2561827 D 63186 CDS YP_004736633.1 340618180 10974996 complement(2564591..2566081) 1 NC_015844.1 The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Signal peptide putatively cleaved between the residues 25 and 26; Possibly localized in the periplasmic space; High confidence in function and specificity; N-sulfoglucosamine sulfohydrolase 2566081 sgsA3 10974996 sgsA3 Zobellia galactanivorans N-sulfoglucosamine sulfohydrolase YP_004736633.1 2564591 R 63186 CDS YP_004736634.1 340618181 10978588 complement(2566101..2567441) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Family membership; sulfatase 2567441 10978588 zobellia_2197 Zobellia galactanivorans sulfatase YP_004736634.1 2566101 R 63186 CDS YP_004736635.1 340618182 10974997 complement(2567458..2569584) 1 NC_015844.1 Modular protein consisting of a N-terminal domain belonging to the family 1 of sulfatases and a C-terminal PA14 domain putatively involved in the protein or carbohydrate binding; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the outer membrane; Family membership; sulfatase 2569584 10974997 zobellia_2198 Zobellia galactanivorans sulfatase YP_004736635.1 2567458 R 63186 CDS YP_004736636.1 340618183 10974998 complement(2569616..2571508) 1 NC_015844.1 Alpha-galactosidase catalyzes the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides. Belongs to the family 110 of the glycoside hydrolases. Likely adopts a right handed parallel beta-helix fold. Signal peptide cleaved between the residues 26 and 27. Localized in the periplasmic space.; High confidence in function and specificity; alpha-galactosidase 2571508 10974998 zobellia_2199 Zobellia galactanivorans alpha-galactosidase YP_004736636.1 2569616 R 63186 CDS YP_004736637.1 340618184 10974999 complement(2571505..2573310) 1 NC_015844.1 Alpha-galactosidase catalyzes the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides. Belongs to the family 110 of the glycoside hydrolases. Likely adopts a right handed parallel beta-helix fold. Signal peptide cleaved between the residues 19 and 20. Localized in the periplasmic space.; High confidence in function and specificity; alpha-galactosidase 2573310 10974999 zobellia_2200 Zobellia galactanivorans alpha-galactosidase YP_004736637.1 2571505 R 63186 CDS YP_004736638.1 340618185 10975001 complement(2573338..2574837) 1 NC_015844.1 The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Lipoprotein with a signal peptide cleaved between the residues 26 and 27; Localized in the outer membrane; High confidence in function and specificity; N-sulfoglucosamine sulfohydrolase 2574837 sgsA4 10975001 sgsA4 Zobellia galactanivorans N-sulfoglucosamine sulfohydrolase YP_004736638.1 2573338 R 63186 CDS YP_004736639.1 340618186 10978589 complement(2574992..2576530) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 2576530 10978589 zobellia_2202 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736639.1 2574992 R 63186 CDS YP_004736640.1 340618187 10975002 complement(2576547..2579666) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules (here, the sulphated sugars) that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (35-109) and the Plug module (125-232) acting as a channel gate; The signal peptide is cleaved between the residues 32 and 33; Family membership; TonB-dependent Receptor 2579666 10975002 zobellia_2203 Zobellia galactanivorans TonB-dependent Receptor YP_004736640.1 2576547 R 63186 CDS YP_004736641.1 340618188 10975003 complement(2579984..2580142) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2580142 10975003 zobellia_2204 Zobellia galactanivorans hypothetical protein YP_004736641.1 2579984 R 63186 CDS YP_004736642.1 340618189 10975004 complement(2580255..2581769) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 15; Signal peptide cleaved between the residues 21 and 22; Possibly localized in the periplasmic space; Family membership; sulfatase 2581769 10975004 zobellia_2205 Zobellia galactanivorans sulfatase YP_004736642.1 2580255 R 63186 CDS YP_004736643.1 340618190 10975005 complement(2581979..2582962) 1 NC_015844.1 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde); Belongs to the xylose isomerase-like TIM barrel family; Exported by the twin-arginine translocation pathway signal; High confidence in function and specificity; hydroxypyruvate isomerase 2582962 10975005 zobellia_2206 Zobellia galactanivorans hydroxypyruvate isomerase YP_004736643.1 2581979 R 63186 CDS YP_004736644.1 340618191 10975006 complement(2582950..2583513) 1 NC_015844.1 Signal peptide putatively cleaved between the residues 19 and 20; Localized in tyhe periplasmic space; hypothetical protein 2583513 10975006 zobellia_2207 Zobellia galactanivorans hypothetical protein YP_004736644.1 2582950 R 63186 CDS YP_004736645.1 340618192 10975007 complement(2583513..2585225) 1 NC_015844.1 FAD-dependent oxidoreductase; Belongs to the GMC oxidoreductase family; Localized in the cytoplasm; Specificity unclear; FAD-dependent oxidoreductase 2585225 10975007 zobellia_2208 Zobellia galactanivorans FAD-dependent oxidoreductase YP_004736645.1 2583513 R 63186 CDS YP_004736646.1 340618193 10975008 complement(2585261..2586763) 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide cleaved between the residue 26 and 27; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 2586763 fucA11 10975008 fucA11 Zobellia galactanivorans alpha-L-fucosidase YP_004736646.1 2585261 R 63186 CDS YP_004736647.1 340618194 10977858 complement(2586778..2588355) 1 NC_015844.1 The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the cytoplasmic membrane or/and outer membrane; High confidence in function and specificity; N-sulfoglucosamine sulfohydrolase 2588355 sgsA5 10977858 sgsA5 Zobellia galactanivorans N-sulfoglucosamine sulfohydrolase YP_004736647.1 2586778 R 63186 CDS YP_004736648.1 340618195 10978590 complement(2588461..2589903) 1 NC_015844.1 Glycoside hydrolase that belongs to the family 36 of glycoside hydrolases (GH36); Exported in the periplasmic space by twin-arginine translocation pathway signal; Family membership; glycoside hydrolase 2589903 10978590 zobellia_2211 Zobellia galactanivorans glycoside hydrolase YP_004736648.1 2588461 R 63186 CDS YP_004736649.1 340618196 10975010 complement(2589911..2591623) 1 NC_015844.1 Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; hypothetical protein 2591623 10975010 zobellia_2212 Zobellia galactanivorans hypothetical protein YP_004736649.1 2589911 R 63186 CDS YP_004736650.1 340618197 10975011 complement(2591638..2592387) 1 NC_015844.1 Acetylesterase that belongs to the lipase-GDSL Pfam family, which includes families 3 and 12 of the carbohydrate esterases (CE3, CE12); The conserved catalytic residues are Ser38, Asp194 and His197. Lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Specificity unclear; lipase-GDSL family acetylesterase 2592387 10975011 zobellia_2213 Zobellia galactanivorans lipase-GDSL family acetylesterase YP_004736650.1 2591638 R 63186 CDS YP_004736651.1 340618198 10975012 complement(2592405..2593988) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Family membership; sulfatase 2593988 10975012 zobellia_2214 Zobellia galactanivorans sulfatase YP_004736651.1 2592405 R 63186 CDS YP_004736652.1 340618199 10975013 complement(2594007..2595527) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Family membership; sulfatase 2595527 10975013 zobellia_2215 Zobellia galactanivorans sulfatase YP_004736652.1 2594007 R 63186 CDS YP_004736653.1 340618200 10975014 complement(2595528..2597072) 1 NC_015844.1 The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Localized in the cytoplasm; High confidence in function and specificity; N-sulfoglucosamine sulfohydrolase 2597072 sgsA6 10975014 sgsA6 Zobellia galactanivorans N-sulfoglucosamine sulfohydrolase YP_004736653.1 2595528 R 63186 CDS YP_004736654.1 340618201 10978591 complement(2597133..2597597) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 2597597 10978591 zobellia_2217 Zobellia galactanivorans lipoprotein YP_004736654.1 2597133 R 63186 CDS YP_004736655.1 340618202 10975015 complement(2597626..2599428) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 2599428 10975015 zobellia_2218 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736655.1 2597626 R 63186 CDS YP_004736656.1 340618203 10975016 complement(2599447..2602542) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules (here, possibly suphated sugars) that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (31-106) and the Plug module (122-225) acting as a channel gate; The signal peptide is cleaved between the residues 29 and 30; Family membership; TonB-dependent Receptor 2602542 10975016 zobellia_2219 Zobellia galactanivorans TonB-dependent Receptor YP_004736656.1 2599447 R 63186 CDS YP_004736657.1 340618204 10975017 complement(2602910..2607025) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 2607025 10975017 zobellia_2220 Zobellia galactanivorans one-component system sensor protein YP_004736657.1 2602910 R 63186 CDS YP_004736658.1 340618205 10975019 complement(2607171..2608238) 1 NC_015844.1 Transferase transferring phosphorus-containing groups; Belongs to the aminoglycoside phosphotransferase family; Localized in the cytoplasm; Family membership; aminoglycoside phosphotransferase family kinase 2608238 10975019 zobellia_2221 Zobellia galactanivorans aminoglycoside phosphotransferase family kinase YP_004736658.1 2607171 R 63186 CDS YP_004736659.1 340618206 10975020 complement(2608238..2609128) 1 NC_015844.1 Enzyme involved in Lipopolysaccharide O antigen biosynthesis. It biosynthetizes UDP-glucose from uridine triphosphate and glucose 1-phosphate; Belongs to the UDPGP type 2 family; Localized in the cytoplasm; High confidence in function and specificity; UTP--glucose-1-phosphate uridylyltransferase 2609128 galF 10975020 galF Zobellia galactanivorans UTP--glucose-1-phosphate uridylyltransferase YP_004736659.1 2608238 R 63186 CDS YP_004736660.1 340618207 10977875 complement(2609333..2610361) 1 NC_015844.1 DeoR-type transcription regulator are repressors of sugar and nucleoside metabolic systems. The effector molecules are generally phosphorylated intermediates of the relevant metabolic pathway. Contains a N-terminal DNA-binding DeoR-type HTH domain. The C-terminal part can contain an effector-binding domain and/or an oligomerization domain; Localized in the cytoplasm; Family membership; DeoR-type transcriptional regulator 2610361 10977875 zobellia_2223 Zobellia galactanivorans DeoR-type transcriptional regulator YP_004736660.1 2609333 R 63186 CDS YP_004736661.1 340618208 10975021 complement(2610443..2611468) 1 NC_015844.1 The LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of operons; They contain a N-terminal lacI-type HTH domain involved in the binding of the protein to the operator sequences in the DNA and a C- terminal periplasmic binding protein domain that are the primary receptors for chemotaxis and transport of many sugar based solutes that act as inducers; Localized in the cytoplasm; Specificity unclear; LacI-type transcriptional regulator 2611468 10975021 zobellia_2224 Zobellia galactanivorans LacI-type transcriptional regulator YP_004736661.1 2610443 R 63186 CDS YP_004736662.1 340618209 10975022 2611665..2614343 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-99) and the Plug module (116-229) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 2614343 10975022 zobellia_2225 Zobellia galactanivorans TonB-dependent Receptor YP_004736662.1 2611665 D 63186 CDS YP_004736663.1 340618210 10975023 2614439..2615749 1 NC_015844.1 Conserved hypothetical protein distantly related to the glycoside hydrolases of the families GH37 and GH63 (clan GH-G); Localized in the cytoplasm; hypothetical protein 2615749 10975023 zobellia_2226 Zobellia galactanivorans hypothetical protein YP_004736663.1 2614439 D 63186 CDS YP_004736664.1 340618211 10975024 complement(2615762..2615992) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2615992 10975024 zobellia_2227 Zobellia galactanivorans hypothetical protein YP_004736664.1 2615762 R 63186 CDS YP_004736665.1 340618212 10975025 2616047..2617651 1 NC_015844.1 Transporter that mediates iodide uptake. Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes. Thereby the energy stored in an inwardly directed electrochemical sodium gradient is used to drive solute accumulation against a concentration gradient; Contains fourteen transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; sodium/iodide symporter 2617651 nisA 10975025 nisA Zobellia galactanivorans sodium/iodide symporter YP_004736665.1 2616047 D 63186 CDS YP_004736666.1 340618213 10978254 2617662..2618786 1 NC_015844.1 Enzyme involved in glycine, serine and threonine metabolism, Glycerolipid metabolism and Glyoxylate and dicarboxylate metabolism; Localized in the cytoplasm; High confidence in function and specificity; glycerate kinase 2618786 glxK 10978254 glxK Zobellia galactanivorans glycerate kinase YP_004736666.1 2617662 D 63186 CDS YP_004736667.1 340618214 10977934 2618940..2619440 1 NC_015844.1 The DNA damage-inducible (din) genes are coordinately regulated and together compose a global regulatory network that has been termed the SOS-like or SOB regulon; Belongs to the DinB family; Localized in the cytoplasm; Function unclear; DinB family protein 2619440 10977934 zobellia_2230 Zobellia galactanivorans DinB family protein YP_004736667.1 2618940 D 63186 CDS YP_004736668.1 340618215 10975027 2619459..2619668 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 2619668 10975027 zobellia_2231 Zobellia galactanivorans hypothetical protein YP_004736668.1 2619459 D 63186 CDS YP_004736669.1 340618216 10975028 2619764..2621125 1 NC_015844.1 Oxygen-independent coproporphyrinogen III oxidase is involved in Porphyrin biosynthesis. It Catalysis the reaction: Coproporphyrinogen-III + 2 S-adenosyl-L-methionine = protoporphyrinogen-IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine; Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine; Localized in the cytoplasm; High confidence in function and specificity; oxygen-independent coproporphyrinogen III oxidase 2621125 hemN 10975028 hemN Zobellia galactanivorans oxygen-independent coproporphyrinogen III oxidase YP_004736669.1 2619764 D 63186 CDS YP_004736670.1 340618217 10977972 2621156..2621977 1 NC_015844.1 Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains two copies of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS- box proteins and bind to DNA; Localized in the cytoplasm; Family membership; universal stress protein 2621977 10977972 zobellia_2233 Zobellia galactanivorans universal stress protein YP_004736670.1 2621156 D 63186 CDS YP_004736671.1 340618218 10975029 complement(2622051..2623442) 1 NC_015844.1 NAD(P)-dependent dehydrogenase; Contains a NAD- and NADP-binding domains with a core Rossmann-type fold; Belongs to the GFO/IDH/MOCA family; Contains an twin-arginine translocation signal peptide; Localized in the cytoplasm; Specificity unclear; NAD(P)-dependent dehydrogenase 2623442 10975029 zobellia_2234 Zobellia galactanivorans NAD(P)-dependent dehydrogenase YP_004736671.1 2622051 R 63186 CDS YP_004736672.1 340618219 10975030 2623619..2624131 1 NC_015844.1 Cytochromes c typically function in electron transfer. They are required during oxidative phosphorylation as an electron shuttle between Complex III (cytochrome c reductase) and IV (cytochrome c oxidase), but c-type cytochrome centers are also found in the active sites of many enzymes; Cytochrome c binds a heme as prosthetic group by Cys93 and Cys96. His97 is involved in iron binding; Belongs to class I (mono-heme) of Cytochrome c; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the cytoplasmic and/or outer membrane; Family membership; cytochrome c 2624131 10975030 zobellia_2235 Zobellia galactanivorans cytochrome c YP_004736672.1 2623619 D 63186 CDS YP_004736673.1 340618220 10975031 2624197..2626158 1 NC_015844.1 Nitrous-oxide reductase is a copper-containing enzyme that catalyses the two-electron reduction of the greenhouse gas N2O to N2. It is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide. Homodimer that Binds 6 copper ions per subunit. Signal peptide of lipoprotein cleaved between the residues 20 and 21. Localized in the cytoplasmic membrane.; High confidence in function and specificity; nitrous oxide reductase 2626158 nosZ 10975031 nosZ Zobellia galactanivorans nitrous oxide reductase YP_004736673.1 2624197 D 63186 CDS YP_004736674.1 340618221 10978263 2626273..2626917 1 NC_015844.1 Contains four transmembranes segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2626917 10978263 zobellia_2237 Zobellia galactanivorans membrane protein YP_004736674.1 2626273 D 63186 CDS YP_004736675.1 340618222 10975032 2626914..2627360 1 NC_015844.1 NosL is one of the accessory lipoproteins of the nos (nitrous oxide reductase) gene cluster. NosL is a monomeric protein that specifically and stoichiometrically binds Cu(I). The copper ion in NosL is ligated by a Cys residue, and one Met and one His are thought to serve as the other ligands. It is possible that NosL is a copper chaperone involved in metallocenter assembly. Signal peptide cleaved between the residues 17 and 18. Localized in the outer membrane.; High confidence in function and specificity; copper-binding lipoprotein 2627360 nosL 10975032 nosL Zobellia galactanivorans copper-binding lipoprotein YP_004736675.1 2626914 D 63186 CDS YP_004736676.1 340618223 10978261 2627374..2627835 1 NC_015844.1 Flavin mononucleotide binding protein belonging to the Pyridoxamine 5'-phosphate oxidase family; The structure could be a FMN-binding split barrel, which is related to the ferredoxin reductase-like FAD-binding domain; Localized in the cytoplasm; Specificity unclear; flavin mononucleotide binding protein 2627835 10978261 zobellia_2239 Zobellia galactanivorans flavin mononucleotide binding protein YP_004736676.1 2627374 D 63186 CDS YP_004736677.1 340618224 10975033 2628082..2629323 1 NC_015844.1 Protein which is thought to insert copper into the exported nitrous oxide reductase apoenzyme (NosZ). Belongs to the nitrous oxide reductase operon. Signal peptide cleaved between the residues 22 and 23. Localized in the periplasmic space.; High confidence in function and specificity; copper-binding periplasmic protein 2629323 nosD 10975033 nosD Zobellia galactanivorans copper-binding periplasmic protein YP_004736677.1 2628082 D 63186 CDS YP_004736678.1 340618225 10978259 2629320..2630030 1 NC_015844.1 This protein, involved in copper processing/transport, is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane). Belongs to the nitrous oxide reductase operon. It is a peripheral membrane protein localized near of the cytoplasmic membrane by association with the permease component.; High confidence in function and specificity; Copper ABC transporter ATPase 2630030 nosF 10978259 nosF Zobellia galactanivorans Copper ABC transporter ATPase YP_004736678.1 2629320 D 63186 CDS YP_004736679.1 340618226 10978260 2630023..2630805 1 NC_015844.1 ABC (ATP-binding cassette) transporter, membrane domain. Proteins responsible for import of multi-copper across biological membranes. Contains six transmembrane segmemts; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane.; High confidence in function and specificity; Copper ABC transporter permease 2630805 nosY 10978260 nosY Zobellia galactanivorans Copper ABC transporter permease YP_004736679.1 2630023 D 63186 CDS YP_004736680.1 340618227 10978262 2630860..2632041 1 NC_015844.1 Contains twelve transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2632041 10978262 zobellia_2243 Zobellia galactanivorans membrane protein YP_004736680.1 2630860 D 63186 CDS YP_004736681.1 340618228 10975035 complement(2632046..2632378) 1 NC_015844.1 Ferredoxins are electron carrier proteins with an iron-sulfur as cofactor and that transfer electrons in a wide variety of metabolic reactions. Belongs to the putidaredoxin, terpredoxin and adrenodoxin sub-family and uses 2Fe-2S cluster as cofactor ligated at four conserved cysteine residues. The general core structure consists of beta(2)-alpha-beta(2). Localized in the cytoplasm.; High confidence in function and specificity; 2Fe-2S ferredoxin 2632378 fdxA2 10975035 fdxA2 Zobellia galactanivorans 2Fe-2S ferredoxin YP_004736681.1 2632046 R 63186 CDS YP_004736682.1 340618229 10977825 complement(2632402..2632749) 1 NC_015844.1 Contains three C-terminal transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2632749 10977825 zobellia_2245 Zobellia galactanivorans membrane protein YP_004736682.1 2632402 R 63186 CDS YP_004736683.1 340618230 10975036 complement(2632809..2633528) 1 NC_015844.1 Involved in peptidoglycan cross-linking. Required for normal cell growth and development. Contains two Hemerythrin HHE cation binding domains.; Family membership; cell wall-like protein ScdA 2633528 scdA 10975036 scdA Zobellia galactanivorans cell wall-like protein ScdA YP_004736683.1 2632809 R 63186 CDS YP_004736684.1 340618231 10978563 complement(2633597..2634031) 1 NC_015844.1 The transcriptional regulators with the Rrf2-type HTH domain control a variety of operons that encode iron-sulfur-containing proteins as well as other proteins involved in electron transport. Other rrf2-type HTH proteins are repressors of genes involved in nitrite or iron metabolism. The C-terminal part of the rrf2-type HTH domain contains 3 conserved cysteine residues that may bind an Fe-S cluster. Contains a DNA-binding, winged helix-turn-helix (wHTH) domain. Localized in the cytoplasm.; Family membership; Rrf2-type transcriptional regulator 2634031 10978563 zobellia_2247 Zobellia galactanivorans Rrf2-type transcriptional regulator YP_004736684.1 2633597 R 63186 CDS YP_004736685.1 340618232 10975037 complement(2634116..2634508) 1 NC_015844.1 Truncated hemoglobin.; Family membership; globin-like protein 2634508 10975037 zobellia_2248 Zobellia galactanivorans globin-like protein YP_004736685.1 2634116 R 63186 CDS YP_004736686.1 340618233 10975038 complement(2634533..2635801) 1 NC_015844.1 Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate.; High confidence in function and specificity; 4-hydroxybutyrate coenzyme A transferase 2635801 cat2 10975038 cat2 Zobellia galactanivorans 4-hydroxybutyrate coenzyme A transferase YP_004736686.1 2634533 R 63186 CDS YP_004736687.1 340618234 10977624 complement(2635935..2637389) 1 NC_015844.1 Vanadium-dependent Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen peroxide forming dioxygen. They are likely to participate in the biosynthesis of halogenated natural products, such as volatile halogenated hydrocarbons, chiral halogenated terpenes, acetogenins and indoles; Signal peptide cleaved between the residues 21 and 22; localized in the periplasmic space; Specificity unclear; vanadium-dependent haloperoxidase 2637389 10977624 zobellia_2250 Zobellia galactanivorans vanadium-dependent haloperoxidase YP_004736687.1 2635935 R 63186 CDS YP_004736688.1 340618235 10975040 complement(2637446..2637943) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2637943 10975040 zobellia_2251 Zobellia galactanivorans membrane protein YP_004736688.1 2637446 R 63186 CDS YP_004736689.1 340618236 10975041 complement(2637971..2638675) 1 NC_015844.1 Belongs to the DsbD family. Like the Cytochrome C biogenesis protein CcdA from Bacillus subtilis, this protein is limited to the transmembrane region of DsbD. Preceded by the cytochrome cbb3 oxidase operon. Features six transmembrane helices. Localized in the cytoplasmic membrane.; Conserved hypothetical protein; cytochrome c biogenesis protein 2638675 ccdA 10975041 ccdA Zobellia galactanivorans cytochrome c biogenesis protein YP_004736689.1 2637971 R 63186 CDS YP_004736690.1 340618237 10977627 complement(2638683..2639129) 1 NC_015844.1 Protein that consists of a FixH family domain. Could be a cytochrome cbb3 oxidase maturation protein; Contains one N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Family membership; FixH-like protein 2639129 ccoH 10977627 ccoH Zobellia galactanivorans FixH-like protein YP_004736690.1 2638683 R 63186 CDS YP_004736691.1 340618238 10977629 complement(2639148..2640566) 1 NC_015844.1 Belongs to the ccoGHIS operon. Features five transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; 4Fe-4S ferredoxin 2640566 ccoG 10977629 ccoG Zobellia galactanivorans 4Fe-4S ferredoxin YP_004736691.1 2639148 R 63186 CDS YP_004736692.1 340618239 10977628 complement(2640612..2641565) 1 NC_015844.1 Belongs to the ccoNOPQ operon. Features three transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; cytochrome cbb3 oxidase subunit CcoP 2641565 ccoP 10977628 ccoP Zobellia galactanivorans cytochrome cbb3 oxidase subunit CcoP YP_004736692.1 2640612 R 63186 CDS YP_004736693.1 340618240 10977632 complement(2641562..2641753) 1 NC_015844.1 CcoQ is a subunit of the cytochrome cbb3 oxidase. Converts the ferrocytochrome c to ferricytochrome c. Belongs to the ccoNOPQ operon. Contains one transmembrane helix; Localized in the cytoplasmic membrane; High confidence in function and specificity; cytochrome cbb3 oxidase subunit CcoQ 2641753 ccoQ 10977632 ccoQ Zobellia galactanivorans cytochrome cbb3 oxidase subunit CcoQ YP_004736693.1 2641562 R 63186 CDS YP_004736694.1 340618241 10977633 complement(2641759..2643963) 1 NC_015844.1 Fusion of the subunits CcoN and CcoO of the Cytochrome cbb3 oxidase. Converts the ferrocytochrome to ferricytochrome. Belongs to the ccoNOQP operon. Contains 13 transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; cytochrome cbb3 oxidase subunit CcoN and CcoO 2643963 ccoNO 10977633 ccoNO Zobellia galactanivorans cytochrome cbb3 oxidase subunit CcoN and CcoO YP_004736694.1 2641759 R 63186 CDS YP_004736695.1 340618242 10977631 complement(2643966..2644175) 1 NC_015844.1 Involved in the ccoGHIS operon. Contains one transmembrane helix; Localized in the cytoplasmic membrane; High confidence in function and specificity; cytochrome cbb3 oxidase maturation protein 2644175 ccoS 10977631 ccoS Zobellia galactanivorans cytochrome cbb3 oxidase maturation protein YP_004736695.1 2643966 R 63186 CDS YP_004736696.1 340618243 10977634 complement(2644375..2644809) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2644809 10977634 zobellia_2259 Zobellia galactanivorans membrane protein YP_004736696.1 2644375 R 63186 CDS YP_004736697.1 340618244 10975042 complement(2644923..2647319) 1 NC_015844.1 Belongs to the cation transport P-type ATPase family. Involved in the ccoGHIS operon. Features eight transmembrane helices. Localized in the cytoplasmic membrane.; Hypothetical protein; cation-transporting P-type ATPase 2647319 ccoI 10975042 ccoI Zobellia galactanivorans cation-transporting P-type ATPase YP_004736697.1 2644923 R 63186 CDS YP_004736698.1 340618245 10977630 2647467..2648156 1 NC_015844.1 This protein complexes with cyclic AMP via an N-terminal cyclic nucleotide-binding domain and binds to specific DNA sites, via a C-terminal crp-type HTH domain, near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA; Probably binds 1 4Fe-4S cluster per subunit as cofactor; Family membership; cAMP-binding regulatory protein, Fnr family 2648156 10977630 zobellia_2261 Zobellia galactanivorans cAMP-binding regulatory protein, Fnr family YP_004736698.1 2647467 D 63186 CDS YP_004736699.1 340618246 10975044 2648244..2649149 1 NC_015844.1 Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains one N-terminal copy of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS-box proteins and bind to DNA; Localized in the cytoplasm; Family membership; universal stress protein 2649149 10975044 zobellia_2262 Zobellia galactanivorans universal stress protein YP_004736699.1 2648244 D 63186 CDS YP_004736700.1 340618247 10975045 2649305..2650582 1 NC_015844.1 NADH dehydrogenases catalyze the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation; Binds 1 FAD noncovalently per subunit; Contains two tranmembrane segments; Belongs to the NADH dehydrogenase family; Localized in the cytoplasmic membrane; High confidence in function and specificity; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 2650582 ndhA2 10975045 ndhA2 Zobellia galactanivorans FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_004736700.1 2649305 D 63186 CDS YP_004736701.1 340618248 10978243 complement(2650618..2650869) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2650869 10978243 zobellia_2264 Zobellia galactanivorans hypothetical protein YP_004736701.1 2650618 R 63186 CDS YP_004736702.1 340618249 10975046 2651198..2652355 1 NC_015844.1 Catalytic activity: Homogentisate + O2 = 4-maleylacetoacetate. Tyrosine metabolism and Styrene degradation.; High confidence in function and specificity; homogentisate 1,2-dioxygenase 2652355 hmgA 10975046 hmgA Zobellia galactanivorans homogentisate 1,2-dioxygenase YP_004736702.1 2651198 D 63186 CDS YP_004736703.1 340618250 10977986 2652420..2652998 1 NC_015844.1 Specificity unclear; NAD(P)H nitroreductase 2652998 10977986 zobellia_2266 Zobellia galactanivorans NAD(P)H nitroreductase YP_004736703.1 2652420 D 63186 CDS YP_004736704.1 340618251 10975047 complement(2653013..2654332) 1 NC_015844.1 Penicillin-binding protein 4* or PBP 4A is probably involved in peptidoglycan biosynthesis. Belongs to the family 12 of the serine peptidases. Signal peptide cleaved between the residues 20 and 21. Localized in the periplasmic space.; High confidence in function and specificity; penicillin-binding protein 4*, family S12 2654332 pbpE 10975047 pbpE Zobellia galactanivorans penicillin-binding protein 4*, family S12 YP_004736704.1 2653013 R 63186 CDS YP_004736705.1 340618252 10978308 complement(2654346..2654894) 1 NC_015844.1 Conserved protein belonging to the DUF456 family. Features four transmembrane helices. Localized in the cytoplasmic membrane.; Conserved hypothetical protein; hypothetical protein 2654894 10978308 zobellia_2268 Zobellia galactanivorans hypothetical protein YP_004736705.1 2654346 R 63186 CDS YP_004736706.1 340618253 10975048 2655071..2655460 1 NC_015844.1 Transcriptional repressor. The BlaI like repressors form homodimers that specifically bind DNA operator/promoter sequences. Followed by a blaR1-like regulator protein.; High confidence in function and specificity; BlaI-type transcriptional repressor 2655460 10975048 zobellia_2269 Zobellia galactanivorans BlaI-type transcriptional repressor YP_004736706.1 2655071 D 63186 CDS YP_004736707.1 340618254 10975049 2655472..2657436 1 NC_015844.1 Modular protein containing a N-terminal BlaR1-like regulatory module and two C-terminal TonB domains. BlaR1-like regulatory proteins are membrane-spanning signal transducers that contain a N-terminal metallopeptidase-M56 domain, possibly involved in the proteolytic inactivation of the BlaI-like repressor, and a central extracellular binding protein domain of unknown specificity. TonB domain, suggested to span the periplasm, is found in the C-terminal part of the protein TonB that is an energy-transducer for TonB-dependent receptors of Gram-negative bacteria; Contains three transmembrane segments; localized in the cytoplasmic membrane; Specificity unclear; BlaR1-type regulatory protein / TonB protein 2657436 10975049 zobellia_2270 Zobellia galactanivorans BlaR1-type regulatory protein / TonB protein YP_004736707.1 2655472 D 63186 CDS YP_004736708.1 340618255 10975051 2657440..2658579 1 NC_015844.1 Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to an oligosaccharide. Contains Tetratricopeptide repeats; Seems to have an uncleavable N-terminal signal sequence; Localized in the cytoplasmic membrane; Specificity unclear; O-linked N-acetylglucosaminyltransferase 2658579 10975051 zobellia_2271 Zobellia galactanivorans O-linked N-acetylglucosaminyltransferase YP_004736708.1 2657440 D 63186 CDS YP_004736709.1 340618256 10975052 complement(2658626..2659183) 1 NC_015844.1 Contains an uncleavable N-terminal signal sequence; hypothetical protein 2659183 10975052 zobellia_2272 Zobellia galactanivorans hypothetical protein YP_004736709.1 2658626 R 63186 CDS YP_004736710.1 340618257 10975053 2659189..2659743 1 NC_015844.1 Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction); Localized in the cytoplasm; High confidence in function and specificity; Crossover junction endodeoxyribonuclease RuvC 2659743 ruvC 10975053 ruvC Zobellia galactanivorans Crossover junction endodeoxyribonuclease RuvC YP_004736710.1 2659189 D 63186 CDS YP_004736711.1 340618258 10978561 2659958..2661091 1 NC_015844.1 Oxygen-independent coproporphyrinogen III oxidase. Involved in Porphyrin biosynthesis. Catalysis of the reaction: Coproporphyrinogen-III + 2 S-adenosyl-L-methionine = protoporphyrinogen-IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine. Binds 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine; Localized in the cytoplasm; High confidence in function and specificity; oxygen-independent coproporphyrinogen III oxidase 2661091 hemN 10978561 hemN Zobellia galactanivorans oxygen-independent coproporphyrinogen III oxidase YP_004736711.1 2659958 D 63186 CDS YP_004736712.1 340618259 10977973 2661176..2661928 1 NC_015844.1 N-formylkynurenine (aryl-) formamidase is an enzyme involved in the tryptophan metabolism. It hydrolyses the N-formyl-L-kynurenine to L-kynurenine and formate; belongs to the cyclase family; Localized in the cytoplasm; High confidence in function and specificity; N-formylkynurenine (aryl-) formamidase 2661928 10977973 zobellia_2275 Zobellia galactanivorans N-formylkynurenine (aryl-) formamidase YP_004736712.1 2661176 D 63186 CDS YP_004736713.1 340618260 10975054 2661925..2662275 1 NC_015844.1 Contains two transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2662275 10975054 zobellia_2276 Zobellia galactanivorans membrane protein YP_004736713.1 2661925 D 63186 CDS YP_004736714.1 340618261 10975055 2662277..2662900 1 NC_015844.1 Protein with an uncleaved signal peptide; Seems localized in the cytoplasmic membrane; hypothetical protein 2662900 10975055 zobellia_2277 Zobellia galactanivorans hypothetical protein YP_004736714.1 2662277 D 63186 CDS YP_004736715.1 340618262 10975056 2662906..2663328 1 NC_015844.1 Localized in the periplasmic space; Family membership; stress responsive A/B barrel domain 2663328 10975056 zobellia_2278 Zobellia galactanivorans stress responsive A/B barrel domain YP_004736715.1 2662906 D 63186 CDS YP_004736716.1 340618263 10975057 2663336..2663884 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 2663884 10975057 zobellia_2279 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004736716.1 2663336 D 63186 CDS YP_004736717.1 340618264 10975058 2663881..2664237 1 NC_015844.1 Conserved hypothetical protein belonging to the MmcQ family; Localized in the cytoplasm; hypothetical protein 2664237 10975058 zobellia_2280 Zobellia galactanivorans hypothetical protein YP_004736717.1 2663881 D 63186 CDS YP_004736718.1 340618265 10975060 2664284..2666056 1 NC_015844.1 The protein MutS is involved in the repair of mismatches in DNA. It plays a key role in the recognition and repair of errors made during the replication of DNA. This protein has a weak ATPase activity; Contains three transmembrane segments and a C-terminal MutS_V domain; Belongs to the MutS family; Localized in the cytoplasmic membrane; High confidence in function and specificity; DNA mismatch repair protein MutS 2666056 mutS3 10975060 mutS3 Zobellia galactanivorans DNA mismatch repair protein MutS YP_004736718.1 2664284 D 63186 CDS YP_004736719.1 340618266 10978214 2666081..2667082 1 NC_015844.1 Possible membrane-bound metal-dependent hydrolase; Contains four N-terminal transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2667082 10978214 zobellia_2282 Zobellia galactanivorans membrane protein YP_004736719.1 2666081 D 63186 CDS YP_004736720.1 340618267 10975061 2667331..2667675 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2667675 10975061 zobellia_2283 Zobellia galactanivorans hypothetical protein YP_004736720.1 2667331 D 63186 CDS YP_004736721.1 340618268 10975062 complement(2667687..2668787) 1 NC_015844.1 Contains two N-terminal transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2668787 10975062 zobellia_2284 Zobellia galactanivorans membrane protein YP_004736721.1 2667687 R 63186 CDS YP_004736722.1 340618269 10975063 complement(2668914..2670599) 1 NC_015844.1 BlaR1-type regulatory proteins are signal-transducing proteins that are a fusion protein with a N-terminal zinc metallopeptidase-M56 domain that proteolytically inactivate the cytoplasmic BlaI-type transcriptional repressor, and a beta-lactams-binding domain; Contains at least four transmembrane segments; Localized in the cytoplasmic membrane; Specificity unclear; BlaR1-type regulatory protein 2670599 10975063 zobellia_2285 Zobellia galactanivorans BlaR1-type regulatory protein YP_004736722.1 2668914 R 63186 CDS YP_004736723.1 340618270 10975064 complement(2670602..2671045) 1 NC_015844.1 BlaI-type transcriptional regulator are repressors usually involved in regulation of resistance to beta-lactams; The N-terminal region of these proteins is involved in DNA operator sequence recognition, while the C-terminal is responsible for dimerisation of the protein; Localized in the cytoplasm; High confidence in function and specificity; BlaI-type transcriptional regulator 2671045 10975064 zobellia_2286 Zobellia galactanivorans BlaI-type transcriptional regulator YP_004736723.1 2670602 R 63186 CDS YP_004736724.1 340618271 10975065 2671261..2671839 1 NC_015844.1 Zn-ribbon-containing protein involved in phosphonate metabolism; Family membership; PhnA protein 2671839 phnA 10975065 phnA Zobellia galactanivorans PhnA protein YP_004736724.1 2671261 D 63186 CDS YP_004736725.1 340618272 10978344 complement(2671880..2673268) 1 NC_015844.1 Peptidase family M20 contains exopeptidases: carboxypeptidases, dipeptidases and a specialised aminopeptidase. These peptidases are of the 'co- catalytic' type, binding two metal ions per monomer of protein. The roles of the two catalytic zinc ions can be described as stabilization of the tetrahedral intermediate and activation of the catalytic water molecule.; Specificity unclear; metallopeptidase 2673268 10978344 zobellia_2288 Zobellia galactanivorans metallopeptidase YP_004736725.1 2671880 R 63186 CDS YP_004736726.1 340618273 10974035 complement(2673909..2674706) 1 NC_015844.1 Protein consisting to a domain of unknown function DUF1080; Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 2674706 10974035 zobellia_2290 Zobellia galactanivorans membrane protein YP_004736726.1 2673909 R 63186 CDS YP_004736727.1 340618274 10975068 complement(2674798..2676558) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 16 and 17; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 2676558 10975068 zobellia_2291 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736727.1 2674798 R 63186 CDS YP_004736728.1 340618275 10975069 complement(2676568..2680044) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain (50-102)) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (121-195) and a Plug module (211-315) acting as the channel gate; The signal peptide is cleaved between the residue 19 and 20; Family membership; TonB-dependent transducer 2680044 10975069 zobellia_2292 Zobellia galactanivorans TonB-dependent transducer YP_004736728.1 2676568 R 63186 CDS YP_004736729.1 340618276 10975070 complement(2680252..2681421) 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 2681421 10975070 zobellia_2293 Zobellia galactanivorans anti-sigma factor YP_004736729.1 2680252 R 63186 CDS YP_004736730.1 340618277 10975071 complement(2681485..2682021) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 2682021 10975071 zobellia_2294 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004736730.1 2681485 R 63186 CDS YP_004736731.1 340618278 10975072 complement(2682401..2682616) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2682616 10975072 zobellia_2295 Zobellia galactanivorans hypothetical protein YP_004736731.1 2682401 R 63186 CDS YP_004736732.1 340618279 10975073 complement(2682750..2684339) 1 NC_015844.1 Conserved protein containing a N-terminal domain of unknown function and a C-terminal Carbohydrate Binding Module of family 22. Lipoprotein signal peptide cleaved between the residues 23 and 24; Localized in the cytoplasmic membrane; Family membership; lipoprotein 2684339 10975073 zobellia_2296 Zobellia galactanivorans lipoprotein YP_004736732.1 2682750 R 63186 CDS YP_004736733.1 340618280 10975074 complement(2684357..2686069) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 2686069 10975074 zobellia_2297 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736733.1 2684357 R 63186 CDS YP_004736734.1 340618281 10975075 complement(2686087..2689170) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules (here, possibly sugars) that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (30-104) and the Plug module (120-227) acting as a channel gate; The signal peptide is cleaved between the residues 24 and 25; Family membership; TonB-dependent Receptor 2689170 10975075 zobellia_2298 Zobellia galactanivorans TonB-dependent Receptor YP_004736734.1 2686087 R 63186 CDS YP_004736735.1 340618282 10975076 2689443..2689658 1 NC_015844.1 Hypothetical protein; hypothetical protein 2689658 10975076 zobellia_2299 Zobellia galactanivorans hypothetical protein YP_004736735.1 2689443 D 63186 CDS YP_004736736.1 340618283 10975077 complement(2689714..2690010) 1 NC_015844.1 Possibly localized in the cytoplasm; hypothetical protein 2690010 10975077 zobellia_2300 Zobellia galactanivorans hypothetical protein YP_004736736.1 2689714 R 63186 CDS YP_004736737.1 340618284 10975080 2690082..2690402 1 NC_015844.1 Contains one N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2690402 10975080 zobellia_2301 Zobellia galactanivorans hypothetical protein YP_004736737.1 2690082 D 63186 CDS YP_004736738.1 340618285 10975081 complement(2690551..2691366) 1 NC_015844.1 Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains one N-terminal copy of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS-box proteins and bind to DNA; Localized in the cytoplasm; Family membership; universal stress protein 2691366 10975081 zobellia_2302 Zobellia galactanivorans universal stress protein YP_004736738.1 2690551 R 63186 CDS YP_004736739.1 340618286 10975082 complement(2691760..2695863) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 2695863 10975082 zobellia_2303 Zobellia galactanivorans one-component system sensor protein YP_004736739.1 2691760 R 63186 CDS YP_004736740.1 340618287 10975083 complement(2696309..2696542) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2696542 10975083 zobellia_2304 Zobellia galactanivorans hypothetical protein YP_004736740.1 2696309 R 63186 CDS YP_004736741.1 340618288 10975084 2696784..2699882 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (37-110) and the Plug module (126-232) acting as a channel gate; The signal peptide is cleaved between the residues 33 and 34; Family membership; TonB-dependent Receptor 2699882 10975084 zobellia_2305 Zobellia galactanivorans TonB-dependent Receptor YP_004736741.1 2696784 D 63186 CDS YP_004736742.1 340618289 10975085 2699895..2701640 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 21 and 22; Probably localized in the cytoplasmic membrane; Family membership; SusD/RagB family lipoprotein 2701640 10975085 zobellia_2306 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736742.1 2699895 D 63186 CDS YP_004736743.1 340618290 10975086 2701657..2703330 1 NC_015844.1 Conserved protein containing a N-terminal domain of unknown function and a C-terminal Carbohydrate Binding Module of the family 22; Lipoprotein signal peptide cleaved between 17 and 18; Localized in the outer membrane; Specificity unclear; lipoprotein 2703330 10975086 zobellia_2307 Zobellia galactanivorans lipoprotein YP_004736743.1 2701657 D 63186 CDS YP_004736744.1 340618291 10975087 2703596..2706616 1 NC_015844.1 Shows a weak similarity with the glycoside hydrolases of the family 42 (GH42); Seems to be a lipoprotein with a signal peptide cleaved between residues 15 and 16; Putatively localised in the outer membrane; hypothetical protein 2706616 10975087 zobellia_2308 Zobellia galactanivorans hypothetical protein YP_004736744.1 2703596 D 63186 CDS YP_004736745.1 340618292 10975088 2706948..2707115 1 NC_015844.1 Peptide that represents a C-terminal fragment of putative sialic-acid O-acetylesterase; Localized in the cytoplasm; hypothetical protein 2707115 10975088 zobellia_2309 Zobellia galactanivorans hypothetical protein YP_004736745.1 2706948 D 63186 CDS YP_004736746.1 340618293 10975089 complement(2707128..2710211) 1 NC_015844.1 Modular protein with a N-terminal beta-galactosidase domain belonging to the family 2 of glycoside hydrolases (GH2, TIM alpha/beta barrel fold) and a C-terminal Carbohydrate Binding Module of family CBM35; Catalyzes the hydrolysis of the beta-1,4 linkage at the terminal non-reducing, releasing a beta-D-galactose residue from beta-D-galactosides; Signal peptide cleaved between residues 28 and 29; Localized in the periplasmic space; High confidence in function and specificity; beta-galactosidase 2710211 bgaE 10975089 bgaE Zobellia galactanivorans beta-galactosidase YP_004736746.1 2707128 R 63186 CDS YP_004736747.1 340618294 10977597 2710607..2710915 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2710915 10977597 zobellia_2311 Zobellia galactanivorans membrane protein YP_004736747.1 2710607 D 63186 CDS YP_004736748.1 340618295 10975091 2711146..2713515 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (24-109) and the Plug module (117-223) acting as the channel gate; The signal peptide is cleaved between the residue 20 and 21; Family membership; TonB-dependent Receptor 2713515 10975091 zobellia_2312 Zobellia galactanivorans TonB-dependent Receptor YP_004736748.1 2711146 D 63186 CDS YP_004736749.1 340618296 10975092 2713527..2714333 1 NC_015844.1 Contains a signal peptide of lipoprotein cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 2714333 10975092 zobellia_2313 Zobellia galactanivorans lipoprotein YP_004736749.1 2713527 D 63186 CDS YP_004736750.1 340618297 10975093 2714394..2714867 1 NC_015844.1 Signal peptide of lipoproteins cleaved between residues 19 and 20; Probably localised in the outer membrane; Conserved hypothetical protein; lipoprotein 2714867 10975093 zobellia_2314 Zobellia galactanivorans lipoprotein YP_004736750.1 2714394 D 63186 CDS YP_004736751.1 340618298 10975094 complement(2715028..2717958) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain (59-110)) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (120-194) and the Plug module (212-335); The signal peptide is cleaved between the residue 29 and 30; Family membership; TonB-dependent transducer 2717958 10975094 zobellia_2315 Zobellia galactanivorans TonB-dependent transducer YP_004736751.1 2715028 R 63186 CDS YP_004736752.1 340618299 10975095 complement(2718032..2719198) 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 2719198 10975095 zobellia_2316 Zobellia galactanivorans anti-sigma factor YP_004736752.1 2718032 R 63186 CDS YP_004736753.1 340618300 10975096 2719294..2719848 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 2719848 10975096 zobellia_2317 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004736753.1 2719294 D 63186 CDS YP_004736754.1 340618301 10975097 complement(2719875..2721068) 1 NC_015844.1 Fumarylacetoacetate hydrolase (FAH), or fumarylacetoacetase (FAA) is the last enzyme in the tyrosine catabolic pathway, it hydrolyses fumarylacetoacetate into fumarate and acetoacetate which then join the citric acid cycle; Localized in the cytoplasm; High confidence in function and specificity; fumarylacetoacetate hydrolase 2721068 10975097 zobellia_2318 Zobellia galactanivorans fumarylacetoacetate hydrolase YP_004736754.1 2719875 R 63186 CDS YP_004736755.1 340618302 10975098 2721516..2722367 1 NC_015844.1 Protein exported in the periplasmic space by the twin-arginine translocation pathway caracterised by a non-Sec signal sequences; The signal peptide is cleaved between residues 33 and 34; Family membership; sugar phosphate isomerases/epimerases 2722367 10975098 zobellia_2319 Zobellia galactanivorans sugar phosphate isomerases/epimerases YP_004736755.1 2721516 D 63186 CDS YP_004736756.1 340618303 10975099 2722377..2723720 1 NC_015844.1 NAD(P)-dependent dehydrogenase. Belongs to the Rossmann fold family. Features a twin-arginine translocation signal peptide cleaved between the residues 29 and 30. Localized in the periplasm.; Specificity unclear; NAD(P)-dependent dehydrogenase 2723720 10975099 zobellia_2320 Zobellia galactanivorans NAD(P)-dependent dehydrogenase YP_004736756.1 2722377 D 63186 CDS YP_004736757.1 340618304 10975101 complement(2724143..2725378) 1 NC_015844.1 KtdA catalyzes the transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). This is a essential step in lipopolysaccharides biosynthesis. KtdA belongs to the family 30 of glycosyltransferases.; High confidence in function and specificity; 3-deoxy-D-manno-octulosonic-acid transferase 2725378 kdtA 10975101 kdtA Zobellia galactanivorans 3-deoxy-D-manno-octulosonic-acid transferase YP_004736757.1 2724143 R 63186 CDS YP_004736758.1 340618305 10978059 2725470..2726624 1 NC_015844.1 PorR belongs to the DegT/DnrJ/EryC1/StrS aminotransferase family, which is included in the pyridoxal-phosphate (PLP)-dependent aminotransferase superfamily. PorR is involved in the biosynthesis of cell surface polysaccharides. In Porphyromonas gingivalis the porR mutant showed a pleiotropic phenotype: loss of pigmentation, delayed maturation of fimbrillin, preferential presence of Rgp and Kgp proteinases in culture supernatants, and no haemagglutination.; Specificity unclear; PorR protein, PLP-dependent aminotransferase family 2726624 porR 10978059 porR Zobellia galactanivorans PorR protein, PLP-dependent aminotransferase family YP_004736758.1 2725470 D 63186 CDS YP_004736759.1 340618306 10978366 2726732..2727748 1 NC_015844.1 GalE interconverts UDP-glucose and UDP-galactose which are precursors of glucose- and galactose-containing exopolysaccharides (EPS). Belongs to the NAD dependent epimerase/dehydratase family, which is included in the Rossmann fold Superfamily.; High confidence in function and specificity; UDP-glucose 4-epimerase 2727748 galE 10978366 galE Zobellia galactanivorans UDP-glucose 4-epimerase YP_004736759.1 2726732 D 63186 CDS YP_004736760.1 340618307 10977874 2727829..2728182 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2728182 10977874 zobellia_2324 Zobellia galactanivorans hypothetical protein YP_004736760.1 2727829 D 63186 CDS YP_004736761.1 340618308 10975102 complement(2728179..2728715) 1 NC_015844.1 Signal peptide cleaved between the residues 27 and 28; Putatively localised in the outer membrane; Hypothetical protein; hypothetical protein 2728715 10975102 zobellia_2325 Zobellia galactanivorans hypothetical protein YP_004736761.1 2728179 R 63186 CDS YP_004736762.1 340618309 10975103 2728813..2731626 1 NC_015844.1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3); High confidence in function and specificity; 2-oxoglutarate dehydrogenase E1 component 2731626 sucA 10975103 sucA Zobellia galactanivorans 2-oxoglutarate dehydrogenase E1 component YP_004736762.1 2728813 D 63186 CDS YP_004736763.1 340618310 10978614 2731675..2732892 1 NC_015844.1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3); Protein contains a biotinyl/lipoyl domain; High confidence in function and specificity; dihydrolipoamide succinyltransferase E2 component 2732892 sucB 10978614 sucB Zobellia galactanivorans dihydrolipoamide succinyltransferase E2 component YP_004736763.1 2731675 D 63186 CDS YP_004736764.1 340618311 10978615 complement(2732991..2733431) 1 NC_015844.1 This enzyme belongs to the family 2 of the aspartic peptidases. An activated water molecule is the nucleophile these peptidases and is bound by two aspartic residues, one from each monomer of the homo-dimeric molecule. Localized in the cytoplasm.; Specificity unclear; aspartic peptidase 2733431 10978615 zobellia_2328 Zobellia galactanivorans aspartic peptidase YP_004736764.1 2732991 R 63186 CDS YP_004736765.1 340618312 10975104 2733469..2734236 1 NC_015844.1 TatD is a cytoplasmic protein with DNase activity; Family membership; Mg-dependent DNase 2734236 tatD 10975104 tatD Zobellia galactanivorans Mg-dependent DNase YP_004736765.1 2733469 D 63186 CDS YP_004736766.1 340618313 10978642 2734268..2735299 1 NC_015844.1 Asparaginase, which is found in various plant, animal and bacterial cells, catalyses the deamination of asparagine to yield aspartic acid and an ammonium ion.; High confidence in function and specificity; asparaginase, type I 2735299 ansA 10978642 ansA Zobellia galactanivorans asparaginase, type I YP_004736766.1 2734268 D 63186 CDS YP_004736767.1 340618314 10974036 2735748..2736494 1 NC_015844.1 ExbB is involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. ExbB protects ExbD from proteolytic degradation and functionally stabilizes tonB. TonB is coupled to the protomotive force by the ExbB/ExbD complex which is required for the energization of TonB; Contains four transmembrane segments; Belongs to the ExbB/TolQ family; Signal peptide cleaved between residues 23 and 24; Localized in the cytoplasmic membrane; High confidence in function and specificity; biopolymer transport protein ExbB 2736494 exbB 10974036 exbB Zobellia galactanivorans biopolymer transport protein ExbB YP_004736767.1 2735748 D 63186 CDS YP_004736768.1 340618315 10977790 2736520..2736960 1 NC_015844.1 Contains 4 transmembrane segmemts; Probably localised in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2736960 10977790 zobellia_2333 Zobellia galactanivorans membrane protein YP_004736768.1 2736520 D 63186 CDS YP_004736769.1 340618316 10975105 2736976..2737602 1 NC_015844.1 ExbD is involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. ExbD forms a complex with ExbB. This complex is required for the efficient energization of tonB from the protomotive force; Contains a N-terminal transmembrane helix; Belongs to the exbD/tolR family; Localized in the cytoplasmic membrane; High confidence in function and specificity; biopolymer transport protein ExbD 2737602 exbD1 10975105 exbD1 Zobellia galactanivorans biopolymer transport protein ExbD YP_004736769.1 2736976 D 63186 CDS YP_004736770.1 340618317 10977791 2737624..2738106 1 NC_015844.1 ExbD is involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. ExbD forms a complex with ExbB. This complex is required for the efficient energization of tonB from the protomotive force; Contains a N-terminal transmembrane helix; Belongs to the exbD/tolR family; Localized in the cytoplasmic membrane; High confidence in function and specificity; biopolymer transport protein ExbD 2738106 exbD2 10977791 exbD2 Zobellia galactanivorans biopolymer transport protein ExbD YP_004736770.1 2737624 D 63186 CDS YP_004736771.1 340618318 10977792 2738188..2738874 1 NC_015844.1 Signal peptide cleaved betwenn the residues 19 and 20; Possibly localized in the outer membrane; Hypothetical protein; hypothetical protein 2738874 10977792 zobellia_2336 Zobellia galactanivorans hypothetical protein YP_004736771.1 2738188 D 63186 CDS YP_004736772.1 340618319 10975106 complement(2738869..2739474) 1 NC_015844.1 Contains seven transmembrane segments; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2739474 10975106 zobellia_2337 Zobellia galactanivorans hypothetical protein YP_004736772.1 2738869 R 63186 CDS YP_004736773.1 340618320 10975107 complement(2739474..2740934) 1 NC_015844.1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. sigma-54 factors consist of three distinct regions: A conserved N-terminal glutamine-rich region (50 aa) that contains a potential leucine zipper motif. A region which is not conserved. A conserved C-terminal region (350 aa) that contains a second potential leucine zipper, a potential DNA-binding 'helix-turn-helix' motif and a perfectly conserved octapeptide whose function is not known; Localized in the cytoplasm; High confidence in function and specificity; RNA polymerase sigma-54 2740934 rpoN 10975107 rpoN Zobellia galactanivorans RNA polymerase sigma-54 YP_004736773.1 2739474 R 63186 CDS YP_004736774.1 340618321 10978529 complement(2740983..2742416) 1 NC_015844.1 AsparaginyltRNA synthetase catalyse the attachment of the aminoacid asparagine to the 3'-hydroxyl of the tRNA. It is an homodimer; Belongs to the class-II aminoacyl-tRNA synthetase family; Localized in the cytoplasm; High confidence in function and specificity; asparaginyl-tRNa synthetase 2742416 AsnS 10978529 AsnS Zobellia galactanivorans asparaginyl-tRNa synthetase YP_004736774.1 2740983 R 63186 CDS YP_004736775.1 340618322 10977562 complement(2742495..2744891) 1 NC_015844.1 The acrA and acrB genes encode a multi-drug efflux system that is believed to protect the bacterium against hydrophobic inhibitors; Integral cytoplasmic membrane protein which contains 12 transmembrane helices and two sterol-sensing domains (SSD); Family membership; acriflavin resistance protein 2744891 acrB 10977562 acrB Zobellia galactanivorans acriflavin resistance protein YP_004736775.1 2742495 R 63186 CDS YP_004736776.1 340618323 10977469 complement(2745027..2745581) 1 NC_015844.1 The ribosome recycling factor dissociates ribosomes from mRNA after termination of translation, and is essential for bacterial growth. Thus ribosomes are 'recycled' and ready for another round of protein synthesis; Localized in the cytoplasm; High confidence in function and specificity; ribosome recycling factor 2745581 rrfA 10977469 rrfA Zobellia galactanivorans ribosome recycling factor YP_004736776.1 2745027 R 63186 CDS YP_004736777.1 340618324 10978553 complement(2745626..2746333) 1 NC_015844.1 Uridylate kinase, also called UMP kinase, converts UMP to UDP by adding a phosphate from ATP. It is the first step in pyrimidine biosynthesis. GTP is an allosteric activator; Localized in the cytoplasm; High confidence in function and specificity; uridylate kinase 2746333 pyrH 10978553 pyrH Zobellia galactanivorans uridylate kinase YP_004736777.1 2745626 R 63186 CDS YP_004736778.1 340618325 10978423 2746514..2748382 1 NC_015844.1 Glycyl aminopeptidase is a metallopeptidase that encompasses a N-terminal catalytic domain and a C-terminal PDZ domain. Its primary function is thought to be in the degradation of extracellular proteins, enabling the efficient uptake of essential amino acids. PDZ domain binds either the carboxyl-terminal sequences of proteins or internal peptide sequences; Belongs to the M61 family of peptidases; Prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the cytoplasmic and/or outer membrane; Specificity unclear; glycyl aminopeptidase 2748382 10978423 zobellia_2343 Zobellia galactanivorans glycyl aminopeptidase YP_004736778.1 2746514 D 63186 CDS YP_004736779.1 340618326 10975109 complement(2748528..2749493) 1 NC_015844.1 The elongation factor Ts or EF-Ts functions in chain elongation during polypeptide synthesis by the ribosome. EF-Ts is a nucleotide exchange factor that is required to regenerate EF-Tu from its inactive form (EF-Tu- GDP) to its active form (EF-Tu-GTP). EF-Tu is then ready to interact with a new aminoacyl-tRNA to begin the cycle again. EF-Ts remains bound to the aminoacyl-tRNA-EF-Tu-GTP complex up to the GTP hydrolysis stage on the ribosome. EF- Ts binds to the EF-Tu-GDP complex and induces the exchange of GDP to GTP; Belongs to the EF-Ts family; Localized in the cytoplasm; High confidence in function and specificity; elongation factor Ts (eF-Ts) 2749493 tsfA 10975109 tsfA Zobellia galactanivorans elongation factor Ts (eF-Ts) YP_004736779.1 2748528 R 63186 CDS YP_004736780.1 340618327 10978713 complement(2749603..2750676) 1 NC_015844.1 The ribosomal protein S2 is a part of the ribosomal small subunit (30S) that contributes to the structural integrity of the ribosome; Belongs to the ribosomal protein S2p family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S2 2750676 rpsB 10978713 rpsB Zobellia galactanivorans 30S ribosomal protein S2 YP_004736780.1 2749603 R 63186 CDS YP_004736781.1 340618328 10978532 complement(2750936..2751322) 1 NC_015844.1 The ribosomal protein S9 is a part of the ribosomal small subunit (30S) that contributes to the structural integrity of the ribosome; Belongs to the ribosomal protein S9p/S16e family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S9 2751322 rpsI 10978532 rpsI Zobellia galactanivorans 30S ribosomal protein S9 YP_004736781.1 2750936 R 63186 CDS YP_004736782.1 340618329 10978539 complement(2751322..2751777) 1 NC_015844.1 The ribosomal protein L13 is a part of the ribosomal large subunit (50S) that contributes to the structural integrity of the 50S ribosomal subunit; L13 is known to be one of the early assembly proteins of the 50S ribosomal subunit. It is important during the early stages of 50S assembly; Belongs to the ribosomal protein L13p family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L13 2751777 rplM 10978539 rplM Zobellia galactanivorans 50S ribosomal protein L13 YP_004736782.1 2751322 R 63186 CDS YP_004736783.1 340618330 10978503 complement(2752143..2752490) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Hypothetical protein; hypothetical protein 2752490 10978503 zobellia_2348 Zobellia galactanivorans hypothetical protein YP_004736783.1 2752143 R 63186 CDS YP_004736784.1 340618331 10975110 complement(2752593..2755424) 1 NC_015844.1 Pol I is responsible for the replication of the late strand during DNA replication. Pol I exhibits a 3' to 5' (Exo II activity) and a 5' to 3' (Exo VI activity) exonuclease activities. The polymerase and Exo VI activities allow to fill the gaps present between the Okasaki's fragments. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template. Pol I also is involved in the DNA repair; Belongs to the family A of DNA polymerases; Localized in the cytoplasm; High confidence in function and specificity; DNA polymerase I (POL I) 2755424 polA 10975110 polA Zobellia galactanivorans DNA polymerase I (POL I) YP_004736784.1 2752593 R 63186 CDS YP_004736785.1 340618332 10978360 complement(2755483..2756472) 1 NC_015844.1 Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins; Protein exported in the periplasmic space; Protein contains a Twin-arginine translocation pathway signal that does not use the standard general secretory (Sec) pathway; Heterodimer of an alpha and a beta chain; High confidence in function and specificity; glycosylasparaginases 2 2756472 aspG 10978360 aspG Zobellia galactanivorans glycosylasparaginases 2 YP_004736785.1 2755483 R 63186 CDS YP_004736786.1 340618333 10977563 2756537..2757259 1 NC_015844.1 Uncharacterized protein involved in copper homeostasis and in copper resistance; Belongs to the cutC family; Localized in the cytoplasm; Function unclear; Copper homeostasis protein 2757259 cutC 10977563 cutC Zobellia galactanivorans Copper homeostasis protein YP_004736786.1 2756537 D 63186 CDS YP_004736787.1 340618334 10977692 2757308..2758531 1 NC_015844.1 Protein that catalyzes the hydrolysis of any phospho ester bond; Contains four transmembrane segments; Binds 2 divalent metal cations; Belongs to the metallophosphoesterase superfamily; Localized in the cytoplasmic membrane; Specificity unclear; metallophosphoesterase 2758531 10977692 zobellia_2352 Zobellia galactanivorans metallophosphoesterase YP_004736787.1 2757308 D 63186 CDS YP_004736788.1 340618335 10975112 2758628..2758924 1 NC_015844.1 Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond; In this protein, the catalytic cysteins are replaced by an asparagine and by a serine; Family membership; thioredoxin like protein 2758924 trxA 10975112 trxA Zobellia galactanivorans thioredoxin like protein YP_004736788.1 2758628 D 63186 CDS YP_004736789.1 340618336 10978706 complement(2759056..2762442) 1 NC_015844.1 Contains 13 transmembrane segments; Integral cytoplasmic membrane protein; Conserved hypothetical protein; membrane protein 2762442 10978706 zobellia_2354 Zobellia galactanivorans membrane protein YP_004736789.1 2759056 R 63186 CDS YP_004736790.1 340618337 10974037 complement(2762858..2764225) 1 NC_015844.1 The Sodium/hydrogen exchanger regulates the cytoplasmic pH, extruding the H+ generated during metabolism. It is involved also in the regulation of cell volume and in salt tolerance, due to Na+ uptake; Contains 13 transmembrane segmemts and a large cytoplasmic region at the carboxyl terminus; Belongs to the Na(+)/H(+) exchanger family; Integral cytoplasmic membrane protein; Family membership; sodium/hydrogen exchanger 2764225 nhaC 10974037 nhaC Zobellia galactanivorans sodium/hydrogen exchanger YP_004736790.1 2762858 R 63186 CDS YP_004736791.1 340618338 10978249 2764418..2764879 1 NC_015844.1 Protein that would associate with RNA to form the core domain of the ribonucleoprotein particles involved in a variety of RNA processing events as mRNA degradation; Contains a domain of unknown function 150 (DUF 150); Could belong to the Sm_like Superfamily; Localized in the Cytoplasm; hypothetical protein 2764879 10978249 zobellia_2357 Zobellia galactanivorans hypothetical protein YP_004736791.1 2764418 D 63186 CDS YP_004736792.1 340618339 10975114 2764896..2766128 1 NC_015844.1 NusA, or N utilisation substance protein A, is a bacterial transcription termination factor. It binds to RNA polymerase alpha subunit and promotes termination at certain RNA hairpin structures; Contains the S1 and KH (type 1) RNA binding motives in the C-terminal part; Localized in the cytoplasm; High confidence in function and specificity; transcription termination factor NusA 2766128 nusA 10975114 nusA Zobellia galactanivorans transcription termination factor NusA YP_004736792.1 2764896 D 63186 CDS YP_004736793.1 340618340 10978281 2766251..2769112 1 NC_015844.1 IF-2 is one of the three factors required for the initiation of protein synthesis in bacteria. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Contains a C-terminal GTP binding domain; Belongs to the IF-2 family; Localized in the cytoplasm; High confidence in function and specificity; translation initiation factor 2 2769112 infB 10978281 infB Zobellia galactanivorans translation initiation factor 2 YP_004736793.1 2766251 D 63186 CDS YP_004736794.1 340618341 10978037 complement(2769171..2769599) 1 NC_015844.1 The start methionine has been changed to obtain a signal peptide length more correct. the cleavage site is now between the residues 19 and 20; Putatively periplasmic protein; hypothetical protein 2769599 10978037 zobellia_2360 Zobellia galactanivorans hypothetical protein YP_004736794.1 2769171 R 63186 CDS YP_004736795.1 340618342 10975115 2769778..2771148 1 NC_015844.1 Protein that contains in the N-terminal region (51 to 149) a CytC domain (Cyt C2) and in the C-terminal region (278 to 417) a multiheme CytC (Cyt C552); Contains two transmembrane segmemts; Signal peptide cleaved between residues 30 and 31; Belongs to the Class 1 cytochrome c family, subclass IA/ IB; Localized in the cytoplasmic membrane; Family membership; multiheme cytochrome c 2771148 10975115 zobellia_2361 Zobellia galactanivorans multiheme cytochrome c YP_004736795.1 2769778 D 63186 CDS YP_004736796.1 340618343 10975116 2771183..2774344 1 NC_015844.1 Ferredoxins are iron-sulphur proteins that mediate electron transfer in a range of metabolic reactions; Contains 4 4Fe-4S type ferredoxin domains and a putatif Twin-arginine translocation pathway signal; Localized in the cytoplasmic membrane; Family membership; molybdopterin oxidoreductase, iron-sulfur binding subunit 2774344 hmoA 10975116 hmoA Zobellia galactanivorans molybdopterin oxidoreductase, iron-sulfur binding subunit YP_004736796.1 2771183 D 63186 CDS YP_004736797.1 340618344 10977987 2774378..2776129 1 NC_015844.1 Ferredoxins are iron-sulphur proteins that mediate electron transfer in a range of metabolic reactions; Contains 10 cytoplasmic transmembrane segmemts; Belongs to the nrfD family; Localized in the cytoplasmic membrane; Family membership; molybdopterin oxidoreductase, membrane subunit 2776129 hmoB 10977987 hmoB Zobellia galactanivorans molybdopterin oxidoreductase, membrane subunit YP_004736797.1 2774378 D 63186 CDS YP_004736798.1 340618345 10977988 2776132..2776662 1 NC_015844.1 Contains two transmembrane segments; Localized in the cytoplasmic membrane; hypothetical protein 2776662 10977988 zobellia_2364 Zobellia galactanivorans hypothetical protein YP_004736798.1 2776132 D 63186 CDS YP_004736799.1 340618346 10975117 2776665..2777225 1 NC_015844.1 The protein contains a cytochrome oxydase domain in its C-terminal region (96 to 181); Signal peptide cleaved between the residues 21 and 22; putatively localised in the outer membrane; Family membership; monoheme cytochrome c 2777225 10975117 zobellia_2365 Zobellia galactanivorans monoheme cytochrome c YP_004736799.1 2776665 D 63186 CDS YP_004736800.1 340618347 10975118 2777242..2778570 1 NC_015844.1 Protein contains 10 transmembrane segmemts; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2778570 10975118 zobellia_2366 Zobellia galactanivorans membrane protein YP_004736800.1 2777242 D 63186 CDS YP_004736801.1 340618348 10975119 2778601..2779710 1 NC_015844.1 Cytochrome c oxidase is an oligomeric enzymatic complex which is a component of the respiratory chain and is involved in the transfer of electrons from cytochrome c to oxygen catalyzing the reduction of oxygen to water; Subunit II (CO II) transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit I; Contains three transmembrane segmemts; Signal sequence cleaved between the residues 16 and 17; Localized in the cytoplasmic membrane; High confidence in function and specificity; cytochrome c oxidase subunit II 2779710 coxM 10975119 coxM Zobellia galactanivorans cytochrome c oxidase subunit II YP_004736801.1 2778601 D 63186 CDS YP_004736802.1 340618349 10977670 2779777..2781606 1 NC_015844.1 Cytochrome c oxidase is an oligomeric enzymatic complex which is a component of the respiratory chain and is involved in the transfer of electrons from cytochrome c to oxygen catalyzing the reduction of oxygen to water; Subunit I (CO I) is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred, via the copper A center of subunit II and a low-spin heme (heme a) of subunit 1, to the CuB-heme a3 (or heme o) bimetallic center of subunit 1; contains 12 transmembrane segmemts; Localized in the cytoplasmic membrane; High confidence in function and specificity; cytochrome c oxidase subunit I 2781606 coxN 10977670 coxN Zobellia galactanivorans cytochrome c oxidase subunit I YP_004736802.1 2779777 D 63186 CDS YP_004736803.1 340618350 10977671 2781764..2782585 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2782585 10977671 zobellia_2369 Zobellia galactanivorans hypothetical protein YP_004736803.1 2781764 D 63186 CDS YP_004736804.1 340618351 10975120 complement(2782607..2784871) 1 NC_015844.1 Acyl-coA oxidase, with FAD cofactor, converts acyl-CoA into trans-2-enoyl-CoA; Acts on CoA derivatives of fatty acids with chain length from C(8) to C(18); Family membership; acyl-coenzyme A oxidase 2784871 acxA 10975120 acxA Zobellia galactanivorans acyl-coenzyme A oxidase YP_004736804.1 2782607 R 63186 CDS YP_004736805.1 340618352 10977472 2784991..2786013 1 NC_015844.1 The RuvB protein makes up part of the RuvABC resolvasome which catalyses the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalysed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein; Enzyme ATP-dependent; Forms a complex with ruvA; Localized in the cytoplasm; High confidence in function and specificity; Holliday junction DNA helicase 2786013 ruvB 10977472 ruvB Zobellia galactanivorans Holliday junction DNA helicase YP_004736805.1 2784991 D 63186 CDS YP_004736806.1 340618353 10978560 2786015..2786935 1 NC_015844.1 Ferredoxins are iron-sulphur proteins that mediate electron transfer in a range of metabolic reactions; Localized in the cytoplasm; Family membership; 4Fe-4S ferredoxin 2786935 10978560 zobellia_2372 Zobellia galactanivorans 4Fe-4S ferredoxin YP_004736806.1 2786015 D 63186 CDS YP_004736807.1 340618355 10975122 complement(2786987..2787079) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2787079 10975122 zobellia_2374 Zobellia galactanivorans hypothetical protein YP_004736807.1 2786987 R 63186 CDS YP_004736808.1 340618354 10975124 2787058..2788383 1 NC_015844.1 Conserved transporter belonging to the Major Facilitator Superfamily. Features eleven transmembrane helices. Localized in the cytoplasmic membrane.; Family membership; major Facilitator Superfamily transporter 2788383 10975124 zobellia_2373 Zobellia galactanivorans major Facilitator Superfamily transporter YP_004736808.1 2787058 D 63186 CDS YP_004736809.1 340618356 10975123 2788497..2790794 1 NC_015844.1 Bifunctional protein: Malic enzyme (N-terminal domain, 1 to 550) and Phosphate acetyl/butaryl transferase (C-terminal domain, 550 to 765); High confidence in function and specificity; NADP-dependent malate dehydrogenase / phosphate acetyl/butaryl transferase 2790794 maeB 10975123 maeB Zobellia galactanivorans NADP-dependent malate dehydrogenase / phosphate acetyl/butaryl transferase YP_004736809.1 2788497 D 63186 CDS YP_004736810.1 340618357 10978118 2790850..2791431 1 NC_015844.1 RuvA forms a complex with RuvB, RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB; RuvAB is an helicase that mediates the Holliday junction migration by localized denaturation and reannealing; RuvA consists of three distinct domains. The N-terminal domain has an oligonucleotide/oligosaccharide binding structure (OB-fold), the middle part contains an HhH motif and the C-terminal domain plays a significant role in the ATP-dependent branch migration of the hetero-duplex through direct contact with RuvB making no interaction with DNA; Localized in the cytoplasm; High confidence in function and specificity; Holliday junction DNA helicase 2791431 ruvA 10978118 ruvA Zobellia galactanivorans Holliday junction DNA helicase YP_004736810.1 2790850 D 63186 CDS YP_004736811.1 340618358 10978559 2791437..2798612 1 NC_015844.1 Signal peptide cleaved between the resedues 31 and 32; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2798612 sprA 10978559 sprA Zobellia galactanivorans periplasmic protein YP_004736811.1 2791437 D 63186 CDS YP_004736812.1 340618359 10978607 2798758..2799138 1 NC_015844.1 The glycine cleavage system is composed of four proteins: P, T, L and H; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; The H protein binds a single lipoic acid as cofactor covalently bound via a amide linkage to a lysine group; contains a lipoyl-binding domain; Localized in the cytoplasm; High confidence in function and specificity; glycine cleavage system, H protein 2799138 gcvH 10978607 gcvH Zobellia galactanivorans glycine cleavage system, H protein YP_004736812.1 2798758 D 63186 CDS YP_004736813.1 340618360 10977883 2799173..2799532 1 NC_015844.1 Contains a VanZ domain and three transmembrane segmemts; Signal peptide cleaved between the residues 27 and 28; Localized in the cytoplasmic membrane; Family membership; membrane protein 2799532 10977883 zobellia_2379 Zobellia galactanivorans membrane protein YP_004736813.1 2799173 D 63186 CDS YP_004736814.1 340618361 10975125 2799586..2800290 1 NC_015844.1 TonB is an energy-transducer for TonB-dependent receptors of Gram-negative bacteria. Energy flows from the cytoplasmic membrane into the outer membrane via a complex consisting of TonB, ExbB and ExbD proteins which are anchored in the cytoplasmic membrane. TonB interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates; Features a N-terminal transmembrane helix; Belongs to the TonB family; Localized in the cytoplasmic membrane; High confidence in function and specificity; TonB protein 2800290 tonB2 10975125 tonB2 Zobellia galactanivorans TonB protein YP_004736814.1 2799586 D 63186 CDS YP_004736815.1 340618362 10978671 2800464..2801363 1 NC_015844.1 Protoheme IX farnesyltransferase, also called haeme O synthase, converts protoheme IX and farnesyl diphosphate to heme O, an intermediate in the biosynthesis of haeme A; Uses divalent cations such as magnesium or calcium as cofactor; Contains nine transmembrane segmemts; Localized in the cytoplasmic membrane; High confidence in function and specificity; protoheme IX farnesyltransferase 2801363 cyoE/ctaB 10978671 cyoE/ctaB Zobellia galactanivorans protoheme IX farnesyltransferase YP_004736815.1 2800464 D 63186 CDS YP_004736816.1 340618363 10977698 2801368..2801949 1 NC_015844.1 Associates with subunits I, II and IV to form cytochrome c oxidase the terminal enzyme of the respiratory chain; The functional role of subunit III is not yet understood; Contains five transmembrane segmemts; Localized in the cytoplasmic membrane; High confidence in function and specificity; cytochrome c oxidase subunit III 2801949 coxC/ctaE 10977698 coxC/ctaE Zobellia galactanivorans cytochrome c oxidase subunit III YP_004736816.1 2801368 D 63186 CDS YP_004736817.1 340618364 10977669 2802046..2803035 1 NC_015844.1 Cytochrome O terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration; Heterooctamer of two A chains, two B chains, two C chains and two D chains; Contains five transmembrane segmemts; Localized in the cytoplasmic membrane; Family membership; cytochrome O ubiquinol oxidase subunit III 2803035 cyoC 10977669 cyoC Zobellia galactanivorans cytochrome O ubiquinol oxidase subunit III YP_004736817.1 2802046 D 63186 CDS YP_004736818.1 340618365 10977697 2803091..2803474 1 NC_015844.1 Contains three transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2803474 10977697 zobellia_2384 Zobellia galactanivorans membrane protein YP_004736818.1 2803091 D 63186 CDS YP_004736819.1 340618366 10975127 2803573..2804214 1 NC_015844.1 Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2804214 10975127 zobellia_2385 Zobellia galactanivorans membrane protein YP_004736819.1 2803573 D 63186 CDS YP_004736820.1 340618367 10975128 2804241..2804963 1 NC_015844.1 Protein that consists of a SCO1/SenC domain; Belongs to the SCO2/SenC family; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Family membership; membrane protein 2804963 10975128 zobellia_2386 Zobellia galactanivorans membrane protein YP_004736820.1 2804241 D 63186 CDS YP_004736821.1 340618368 10975129 2804964..2805497 1 NC_015844.1 The protein contains five transmembrane segmemts; hypothetical protein 2805497 10975129 zobellia_2387 Zobellia galactanivorans hypothetical protein YP_004736821.1 2804964 D 63186 CDS YP_004736822.1 340618369 10975130 2805536..2805769 1 NC_015844.1 Contains two transmembrane segmemts; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2805769 10975130 zobellia_2388 Zobellia galactanivorans hypothetical protein YP_004736822.1 2805536 D 63186 CDS YP_004736823.1 340618370 10975131 2805868..2807112 1 NC_015844.1 ABC (ATP-binding cassette) membrane domain (subunit 1) possibly involved in the defense mechanisms by extrusion of a variety of compounds such as antibiotics, heavy metals or solvents across biological membranes; Contains four transmembrane segments; Belongs to the ABC transporter family; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 2807112 10975131 zobellia_2389 Zobellia galactanivorans ABC transporter permease YP_004736823.1 2805868 D 63186 CDS YP_004736824.1 340618371 10975132 2807146..2808405 1 NC_015844.1 ABC (ATP-binding cassette) membrane domain (subunit 2) possibly involved in the defense mechanisms by extrusion of a variety of compounds such as antibiotics, heavy metals or solvents across biological membranes; Contains four transmembrane segments; Belongs to the ABC transporter family; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 2808405 10975132 zobellia_2390 Zobellia galactanivorans ABC transporter permease YP_004736824.1 2807146 D 63186 CDS YP_004736825.1 340618372 10975134 2808469..2809581 1 NC_015844.1 The membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics, solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmic membrane by a N-terminal transmembrane region; belongs to the type I secretion system; Family membership; membrane fusion protein 2809581 10975134 zobellia_2391 Zobellia galactanivorans membrane fusion protein YP_004736825.1 2808469 D 63186 CDS YP_004736826.1 340618373 10975135 2809691..2810395 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component of the ABC transporters; Family membership; ABC transporter ATPase 2810395 10975135 zobellia_2392 Zobellia galactanivorans ABC transporter ATPase YP_004736826.1 2809691 D 63186 CDS YP_004736827.1 340618374 10975136 2810385..2811614 1 NC_015844.1 ABC (ATP-binding cassette) membrane domain (subunit 1) possibly involved in the defense mechanisms by extrusion of a variety of compounds such as antibiotics, heavy metals or solvents across biological membranes; Contains four transmembrane segments; Belongs to the ABC transporter family; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 2811614 10975136 zobellia_2393 Zobellia galactanivorans ABC transporter permease YP_004736827.1 2810385 D 63186 CDS YP_004736828.1 340618375 10975137 2811616..2812878 1 NC_015844.1 ABC (ATP-binding cassette) membrane domain (subunit 2) possibly involved in the defense mechanisms by extrusion of a variety of compounds such as antibiotics, heavy metals or solvents across biological membranes; Contains four transmembrane segments; Belongs to the ABC transporter family; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 2812878 10975137 zobellia_2394 Zobellia galactanivorans ABC transporter permease YP_004736828.1 2811616 D 63186 CDS YP_004736829.1 340618376 10975138 2812941..2814083 1 NC_015844.1 The membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics, solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmic membrane by a N-terminal transmembrane region; belongs to the type I secretion system; Family membership; membrane fusion protein 2814083 10975138 zobellia_2395 Zobellia galactanivorans membrane fusion protein YP_004736829.1 2812941 D 63186 CDS YP_004736830.1 340618377 10975139 2814115..2815464 1 NC_015844.1 The outer membrane efflux proteins (OEP) are composed of two repeats of OEP domain to form a trimeric channel continuous, solvent-accessible conduit that spans both the outer membrane and periplasmic space; May be specialized for the signal peptide independent extracellular secretion of a variety of substrates in Gram-negative bacteria (type I secretion); Signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Family membership; outer membrane efflux protein 2815464 10975139 zobellia_2396 Zobellia galactanivorans outer membrane efflux protein YP_004736830.1 2814115 D 63186 CDS YP_004736831.1 340618378 10975140 2815562..2816236 1 NC_015844.1 Hypothetical protein that belongs to the family 22 of the metallopeptidases (M22), but lacks the two conserved catalytic histidines which bind the zinc ion; Localized in the cytoplasm; Family membership; family M22 non-peptidase protein 2816236 10975140 zobellia_2397 Zobellia galactanivorans family M22 non-peptidase protein YP_004736831.1 2815562 D 63186 CDS YP_004736832.1 340618379 10975141 complement(2816241..2817077) 1 NC_015844.1 Small-conductance mechanosensitive channels (MscS) with three transmembrane segments; Mechanosensitive channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation; Contains a Phosphopantetheine attachment site (Prosite result); High confidence in function and specificity; mechanosensitive ion channel 2817077 yggB 10975141 yggB Zobellia galactanivorans mechanosensitive ion channel YP_004736832.1 2816241 R 63186 CDS YP_004736833.1 340618380 10978785 complement(2817306..2817506) 1 NC_015844.1 Protein belonging to the DUF1458 (domain unknown function) family; Localized in the cytoplasm; hypothetical protein 2817506 10978785 zobellia_2399 Zobellia galactanivorans hypothetical protein YP_004736833.1 2817306 R 63186 CDS YP_004736834.1 340618381 10975142 complement(2817590..2818504) 1 NC_015844.1 Some of the Nif proteins are specifically involved in the formation of the Fe-S cluster of nitrogenase and these are found in organisms that do not fix nitrogen; C-terminal domain; Family membership; NifU-like protein 2818504 nifU 10975142 nifU Zobellia galactanivorans NifU-like protein YP_004736834.1 2817590 R 63186 CDS YP_004736835.1 340618382 10978251 2818638..2819651 1 NC_015844.1 Features a signal peptide cleaved between the residues 20 and 21; Localized in the periplasm.; hypothetical protein 2819651 10978251 zobellia_2401 Zobellia galactanivorans hypothetical protein YP_004736835.1 2818638 D 63186 CDS YP_004736836.1 340618383 10975145 complement(2819730..2820917) 1 NC_015844.1 Possible lipoprotein localised in the outer membrane; Sequence signal cleaved between the residues 22 and 23; Contains a von Willebrand factor type A domain; hypothetical protein 2820917 10975145 zobellia_2402 Zobellia galactanivorans hypothetical protein YP_004736836.1 2819730 R 63186 CDS YP_004736837.1 340618384 10975146 2821166..2823121 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Signal peptide cleaved between the residues 22 and 23; Contains one transmembrane segmemt and five tetratrico peptide repeats (TPR); Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 2823121 10975146 zobellia_2403 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004736837.1 2821166 D 63186 CDS YP_004736838.1 340618385 10975147 2823150..2823878 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, that acts as transcriptional regulator; Family membership; two-component system-response regulator 2823878 10975147 zobellia_2404 Zobellia galactanivorans two-component system-response regulator YP_004736838.1 2823150 D 63186 CDS YP_004736839.1 340618386 10975148 2823905..2824414 1 NC_015844.1 PaaY is involved in the catabolism of phenylacetic acid. This protein belongs to the o-acetyltransferase family. Its features four tandem repeats of a [LIV]-G-X(4) hexapeptide, which has been shown to fold as a left-handed parallel beta helix; Localized in the cytoplasm; High confidence in function and specificity; phenylacetic acid degradation o-acetyltransferase 2824414 paaY 10975148 paaY Zobellia galactanivorans phenylacetic acid degradation o-acetyltransferase YP_004736839.1 2823905 D 63186 CDS YP_004736840.1 340618387 10978294 2824485..2825372 1 NC_015844.1 Malonyl CoA-acyl carrier protein transacylase is involved in fatty acid biosynthesis and transfers the malonyl moeity from coenzyme A to acyl-carrier protein; High confidence in function and specificity; malonyl CoA-acyl carrier protein transacylase 2825372 fabD 10978294 fabD Zobellia galactanivorans malonyl CoA-acyl carrier protein transacylase YP_004736840.1 2824485 D 63186 CDS YP_004736841.1 340618388 10977800 2825524..2829228 1 NC_015844.1 Contains two repeats of the calx-motif in the N-terminal domain (residues 34 to 128 and 142 to 254); The calx-motif is present as a tandem repeat in the cytoplasmic domains of Calx Na-Ca exchangers, which are used to expel calcium from cells; Signal peptide cleaved between the residues 35 and 36; Protein possibly localised in the outer membrane (PSORT result); Contains the endopeptidase Clp signature (residues 310-321; Prosite result); Conserved hypothetical protein; hypothetical protein 2829228 10977800 zobellia_2407 Zobellia galactanivorans hypothetical protein YP_004736841.1 2825524 D 63186 CDS YP_004736842.1 340618389 10975149 2829237..2830220 1 NC_015844.1 Signal peptide cleaved between the residues 28 and 29; Localized in the periplasm.; hypothetical protein 2830220 10975149 zobellia_2408 Zobellia galactanivorans hypothetical protein YP_004736842.1 2829237 D 63186 CDS YP_004736843.1 340618390 10975150 2830230..2832167 1 NC_015844.1 This protein has a modular architecture consisting of a N-terminal domain of unknown function, a central beta-propeller domain with three WD40 repeats and a C-terminal OmpA domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Function unclear; OmpA-like outer membrane protein 2832167 10975150 zobellia_2409 Zobellia galactanivorans OmpA-like outer membrane protein YP_004736843.1 2830230 D 63186 CDS YP_004736844.1 340618391 10975151 complement(2832197..2833450) 1 NC_015844.1 Protein that Belongs to the NRAMP family (resistance-associated macrophage protein); This family of membrane proteins are divalent cation transporters; Contains 10 transmembrane segments; Possible peptide signal cleaved between the residues 24 and 25; localized in the cytoplasmic membrane; Family membership; manganese/fer transporter 2833450 10975151 zobellia_2410 Zobellia galactanivorans manganese/fer transporter YP_004736844.1 2832197 R 63186 CDS YP_004736845.1 340618392 10975153 2833791..2836916 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (60-134), a Plug module (150-256) acting as the channel gate; The signal peptide is cleaved between the residue 39 and 40; Family membership; TonB-dependent Receptor 2836916 10975153 zobellia_2411 Zobellia galactanivorans TonB-dependent Receptor YP_004736845.1 2833791 D 63186 CDS YP_004736846.1 340618393 10975154 2836934..2838385 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 2838385 10975154 zobellia_2412 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736846.1 2836934 D 63186 CDS YP_004736847.1 340618394 10975155 2838578..2842009 1 NC_015844.1 ASPIC and UnbV sequences are found associated with tetratrico peptide repeat in several paralogous proteins in the bacteria Rhodopirellula baltica and with FG-GAP repeats in several eukaryotic integrin-like proteins and in several bacterial proteins. In integrins, the FG-GAP repeats are a important region for ligand binding; Contains a putatif lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Function unclear; ASPIC and UnbV-like protein 2842009 10975155 zobellia_2413 Zobellia galactanivorans ASPIC and UnbV-like protein YP_004736847.1 2838578 D 63186 CDS YP_004736848.1 340618395 10975156 complement(2842026..2842661) 1 NC_015844.1 The SanA protein participates in the barrier function of the cell envelope and may be involved in Vancomycin resistance and in murein synthesis; Signal peptide of lipoprotein cleaved between the residues 22 and 23; localized in the outer membrane; High confidence in function and specificity; hypothetical protein 2842661 sanA 10975156 sanA Zobellia galactanivorans hypothetical protein YP_004736848.1 2842026 R 63186 CDS YP_004736849.1 340618396 10978562 complement(2842712..2843011) 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 2843011 10978562 zobellia_2415 Zobellia galactanivorans hypothetical protein YP_004736849.1 2842712 R 63186 CDS YP_004736850.1 340618397 10975157 2843519..2843743 1 NC_015844.1 Hypothetical protein; hypothetical protein 2843743 10975157 zobellia_2416 Zobellia galactanivorans hypothetical protein YP_004736850.1 2843519 D 63186 CDS YP_004736851.1 340618398 10975158 2843740..2862351 1 NC_015844.1 Protein that contains in the N-terminal part, one cadherin like domain and in its C-terminal part, five PKD repeats. The PKD domains are present in the extracellular parts of proteins involved in interactions with other proteins or polysaccharides; Signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; hypothetical protein 2862351 10975158 zobellia_2417 Zobellia galactanivorans hypothetical protein YP_004736851.1 2843740 D 63186 CDS YP_004736852.1 340618399 10975159 complement(2862399..2863598) 1 NC_015844.1 Gamma-glutamyl phosphate reductase (GPR) is the enzyme that catalyzes the second step in the biosynthesis of proline from glutamate: the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate; Belongs to the aldehyde dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity; gamma-glutamyl phosphate reductase 2863598 proA1 10975159 proA1 Zobellia galactanivorans gamma-glutamyl phosphate reductase YP_004736852.1 2862399 R 63186 CDS YP_004736853.1 340618400 10978384 complement(2863599..2864384) 1 NC_015844.1 Glutamate 5-kinase catalyses the first step in the biosynthesis of proline: the ATP-dependent phosphorylation of glutamate to glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline; It belongs to the larger family of aspartokinases; Localized in the cytoplasm; High confidence in function and specificity; glutamate 5-kinase 2864384 proB1 10978384 proB1 Zobellia galactanivorans glutamate 5-kinase YP_004736853.1 2863599 R 63186 CDS YP_004736854.1 340618401 10978386 complement(2864377..2865192) 1 NC_015844.1 Delta 1-pyrroline-5-carboxylate reductase (P5CR) is the enzyme that catalyzes the terminal step in the biosynthesis of proline from glutamate: the NAD(P) dependent oxidation of 1-pyrroline-5-carboxylate into proline; Localized in the cytoplasm; High confidence in function and specificity; pyrroline-5-carboxylate reductase 2865192 proC1 10978386 proC1 Zobellia galactanivorans pyrroline-5-carboxylate reductase YP_004736854.1 2864377 R 63186 CDS YP_004736855.1 340618402 10978388 complement(2865247..2865438) 1 NC_015844.1 Contains a N-terminal transmembrane segment; Possibly localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2865438 10978388 zobellia_2421 Zobellia galactanivorans hypothetical protein YP_004736855.1 2865247 R 63186 CDS YP_004736856.1 340618403 10975161 complement(2866266..2866637) 1 NC_015844.1 Possible lipoprotein with a signal peptide cleaved between the residues 18 and 19; Probably localized in the outer membrane; Hypothetical protein; hypothetical protein 2866637 10975161 zobellia_2422 Zobellia galactanivorans hypothetical protein YP_004736856.1 2866266 R 63186 CDS YP_004736857.1 340618404 10975162 complement(2866792..2867412) 1 NC_015844.1 Signal peptide cleaved between the residues 19 and 20; Possibly localized in the outer membrane; Hypothetical protein; hypothetical protein 2867412 10975162 zobellia_2423 Zobellia galactanivorans hypothetical protein YP_004736857.1 2866792 R 63186 CDS YP_004736858.1 340618405 10975163 complement(2867611..2868810) 1 NC_015844.1 Hypothetical protein possibly localized in the cytoplasm; hypothetical protein 2868810 10975163 zobellia_2424 Zobellia galactanivorans hypothetical protein YP_004736858.1 2867611 R 63186 CDS YP_004736859.1 340618406 10974038 complement(2869448..2869741) 1 NC_015844.1 Contains a transmembrane segment; Probably localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2869741 10974038 zobellia_2426 Zobellia galactanivorans hypothetical protein YP_004736859.1 2869448 R 63186 CDS YP_004736860.1 340618407 10975165 complement(2869716..2870978) 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 2870978 10975165 zobellia_2427 Zobellia galactanivorans hypothetical protein YP_004736860.1 2869716 R 63186 CDS YP_004736861.1 340618408 10975166 complement(2871000..2872601) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; localized in the outer membrane and/or cytoplasmic membrane; Specificity unclear; sulfatase 2872601 10975166 zobellia_2428 Zobellia galactanivorans sulfatase YP_004736861.1 2871000 R 63186 CDS YP_004736862.1 340618409 10975167 complement(2872611..2874524) 1 NC_015844.1 Alpha-glucosidases Catalyse the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose. Involved in carbohydrate metabolism, notably in starch degradation; Belongs to the family 97 of glycoside hydrolases (GH97); Lipoprotein signal peptide cleaved between the residues 21 and 22; Probably localized in the outer membrane; High confidence in function and specificity; alpha-glucosidase 2874524 10975167 zobellia_2429 Zobellia galactanivorans alpha-glucosidase YP_004736862.1 2872611 R 63186 CDS YP_004736863.1 340618410 10975168 complement(2874542..2876122) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 15; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the cytoplasmic or/and outer membrane; Family membership; sulfatase 2876122 10975168 zobellia_2430 Zobellia galactanivorans sulfatase YP_004736863.1 2874542 R 63186 CDS YP_004736864.1 340618411 10975170 complement(2876504..2877655) 1 NC_015844.1 Endo-1,3-beta-glucanase (Laminarinase) hydrolyzes the 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans. This laminarinase is a modular protein with a N-terminal PKD domain and a C-terminal catalytic module of the family 16 of glycoside hydrolases (GH16). Features a signal peptide of lipoprotein putatively cleaved between the residues 30 and 31; Localized in the outer membrane.; High confidence in function and specificity; endo-1,3-beta-glucanase 2877655 lamA 10975170 lamA Zobellia galactanivorans endo-1,3-beta-glucanase YP_004736864.1 2876504 R 63186 CDS YP_004736865.1 340618412 10978072 complement(2877730..2879385) 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2879385 10978072 zobellia_2432 Zobellia galactanivorans membrane protein YP_004736865.1 2877730 R 63186 CDS YP_004736866.1 340618413 10975171 complement(2879416..2881032) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 25 and 26; Putatively localized in the cytoplasmic membrane; Family membership; SusD/RagB family lipoprotein 2881032 10975171 zobellia_2433 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736866.1 2879416 R 63186 CDS YP_004736867.1 340618414 10975172 complement(2881042..2884011) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (22-95) and the Plug module (111-219) acting as a channel gate; Seems to possess a lipoprotein signal peptide is cleaved between the residues 16 and 17; Family membership; TonB-dependent Receptor 2884011 10975172 zobellia_2434 Zobellia galactanivorans TonB-dependent Receptor YP_004736867.1 2881042 R 63186 CDS YP_004736868.1 340618415 10975173 complement(2884285..2887080) 1 NC_015844.1 Protein that consists of an N-terminal periplasmic beta-propeller followed by a C-terminal cytoplasmic domain containing a LuxR-type HTH domain acting as transcrptionnal regulator. A transmembrane segment is present between these two domains. Signal peptide cleaved between the residues 18 and 19; Localized in the cytoplasmic membrane; Family membership; ligand-binding sensor protein 2887080 10975173 zobellia_2435 Zobellia galactanivorans ligand-binding sensor protein YP_004736868.1 2884285 R 63186 CDS YP_004736869.1 340618416 10974040 complement(2887711..2890332) 1 NC_015844.1 The protein MutS is involved in the repair of mismatches in DNA. It plays a key role in the recognition and repair of errors made during the replication of DNA. This protein has a weak ATPase activity; Belongs to the MutS family; Localized in the cytoplasm; High confidence in function and specificity; DNA mismatch repair protein MutS 2890332 mutS1 10974040 mutS1 Zobellia galactanivorans DNA mismatch repair protein MutS YP_004736869.1 2887711 R 63186 CDS YP_004736870.1 340618417 10978212 2890492..2891031 1 NC_015844.1 Catalyzes the site-specific methylation of the 2' hydroxy group of the ribose in rRNA or tRNA, using the S-AdoMet; Contains a N-terminal RNA 2'-O ribose methyltransferase substrate binding domain and a C-terminal catalytic domain also involved in the dimer formation that adopts an alpha/beta knot fold; Belongs to the RNA methyltransferase TrmH family; Localized in the cytoplasm; Family membership; tRNA/rRNA methyltransferase 2891031 10978212 zobellia_2439 Zobellia galactanivorans tRNA/rRNA methyltransferase YP_004736870.1 2890492 D 63186 CDS YP_004736871.1 340618418 10975175 complement(2891028..2892212) 1 NC_015844.1 Modular protein with a N-terminal 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) domain and a C-terminal Deoxyguanosine kinase (DGK) domain. HPPK catalyzes the attachment of pyrophosphate to 6-hydroxymethyl-7,8-dihydropterin to form 6-hydroxymethyl- 7, 8-dihydropteridine pyrophosphate. This is the first step in a three-step pathway leading to 7,8 dihydrofolate. Deoxyguanosine kinase DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism. Localized in the cytoplasm.; High confidence in function and specificity; 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase / deoxyguanosine kinase 2892212 folK 10975175 folK Zobellia galactanivorans 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase / deoxyguanosine kinase YP_004736871.1 2891028 R 63186 CDS YP_004736872.1 340618419 10977841 2892245..2894008 1 NC_015844.1 Signal peptide peptidase A catalyzes the digestion of the cleaved signal peptides. This activity is necessary to maintain proper secretion of mature proteins across the membrane. Forms a homotetramer. Belongs to the family 49 of the serine peptidases. Features a N-terminal transmembrane helix. Localized in the cytoplasmic membrane.; High confidence in function and specificity; signal peptide peptidase A, family s49 2894008 sppA 10977841 sppA Zobellia galactanivorans signal peptide peptidase A, family s49 YP_004736872.1 2892245 D 63186 CDS YP_004736873.1 340618420 10978605 complement(2894083..2896182) 1 NC_015844.1 This protein has a modular architecture consisting of a N-terminal domain of unknown function followed by four Thrombospondin type 3 repeats and a C-terminal OmpA- like domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Signal peptide cleaved between the residues 19 and 20; Probably localized in the outer membrane and/or periplasmic space; Family membership; OmpA-like periplasmic protein 2896182 10978605 zobellia_2442 Zobellia galactanivorans OmpA-like periplasmic protein YP_004736873.1 2894083 R 63186 CDS YP_004736874.1 340618421 10975176 2896277..2896999 1 NC_015844.1 Conserved integral membrane protein belonging to the DUF165 family; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Family membership; hypothetical protein 2896999 10975176 zobellia_2443 Zobellia galactanivorans hypothetical protein YP_004736874.1 2896277 D 63186 CDS YP_004736875.1 340618422 10975177 2897164..2899893 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2899893 10975177 zobellia_2444 Zobellia galactanivorans periplasmic protein YP_004736875.1 2897164 D 63186 CDS YP_004736876.1 340618424 10975178 complement(2900114..2900992) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 2900992 10975178 zobellia_2446 Zobellia galactanivorans hypothetical protein YP_004736876.1 2900114 R 63186 CDS YP_004736877.1 340618423 10975180 2900986..2902500 1 NC_015844.1 Protein distantly related to the Auxin-responsive GH3-like proteins; Localized in the cytoplasm; hypothetical protein 2902500 10975180 zobellia_2445 Zobellia galactanivorans hypothetical protein YP_004736877.1 2900986 D 63186 CDS YP_004736878.1 340618425 10975179 2902575..2903138 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 2903138 10975179 zobellia_2447 Zobellia galactanivorans hypothetical protein YP_004736878.1 2902575 D 63186 CDS YP_004736879.1 340618426 10975181 complement(2903263..2904498) 1 NC_015844.1 Endopeptidase Clp plays a major role in the degradation of misfolded proteins. It is an oligomeric complex constituted by an ATP-binding subunit and a peptidase subunit (ClpP). The subunits form two different ring structures consisting of seven peptidase subunits and six ATP-binding subunits, respectively. ClpX directs the peptidase subunit ClpP to specific substrates. In the absence of ClpP, ClpX is a molecular chaperone; Belongs to the Hsp100 family and to AAA ATPases family; Contains a N-terminal C4-type zinc binding domain (ZBD) involved in substrate recognition; Localized in the cytoplasm; High confidence in function and specificity; endopeptidase Clp, ATP-binding subunit 2904498 clpX 10975181 clpX Zobellia galactanivorans endopeptidase Clp, ATP-binding subunit YP_004736879.1 2903263 R 63186 CDS YP_004736880.1 340618427 10977656 complement(2904596..2905348) 1 NC_015844.1 Endopeptidase Clp plays a major role in the degradation of misfolded proteins. It is an oligomeric complex constituted by an ATP-binding subunit (ClpX) and a peptidase subunit (ClpP). The subunits form two different ring structures consisting of seven peptidase subunits and six ATP-binding subunits, respectively. In absence of ClpX, ClpP can act only on oligopeptides; Belongs to the family S14 of the peptidases; Localized in the cytoplasm; High confidence in function and specificity; endopeptidase Clp, peptidase subunit 2905348 clpP1 10977656 clpP1 Zobellia galactanivorans endopeptidase Clp, peptidase subunit YP_004736880.1 2904596 R 63186 CDS YP_004736881.1 340618428 10977653 complement(2905379..2906701) 1 NC_015844.1 Trigger factor (TF) is involved in protein export. It acts as an ATP-independent chaperone by binding to nascent polypeptide chains via ribosomal protein L23 (RplE) and maintaining the newly synthesized protein in an open conformation. Trigger Factor also displays a peptidyl-prolyl-cis-trans-isomerase (PPIase) activity in vitro. TF is composed of an N-terminal domain that mediates association with the large ribosomal subunit, a central substrate binding and PPIase domain with homology to FKBP proteins, and a C-terminal domain of unknown function. TF forms homodimer and monomer; Localized in the cytoplasm; High confidence in function and specificity; Trigger factor 2906701 tigA 10977653 tigA Zobellia galactanivorans Trigger factor YP_004736881.1 2905379 R 63186 CDS YP_004736882.1 340618429 10978662 complement(2906798..2907148) 1 NC_015844.1 Conserved membrane protein belonging to the DUF360 family. Contains four transmembrane helices; Localized in the cytoplasmic membrane; hypothetical protein 2907148 10978662 zobellia_2451 Zobellia galactanivorans hypothetical protein YP_004736882.1 2906798 R 63186 CDS YP_004736883.1 340618430 10975182 complement(2907262..2908032) 1 NC_015844.1 The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Localized in the cytoplasm; Function unclear; alpha/beta hydrolase-fold protein 2908032 10975182 zobellia_2452 Zobellia galactanivorans alpha/beta hydrolase-fold protein YP_004736883.1 2907262 R 63186 CDS YP_004736884.1 340618431 10975183 complement(2908033..2908746) 1 NC_015844.1 Pyridoxine 5'-phosphate synthase catalyzes the condensation between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP), the active form of vitamin B6 used as coenzyme in a multitude of reactions, including decarboxylation, deamination and transamination; Belongs to the PNP synthase family; Localized in the cytoplasm; High confidence in function and specificity; pyridoxine 5'-phosphate synthase 2908746 pdxJ 10975183 pdxJ Zobellia galactanivorans pyridoxine 5'-phosphate synthase YP_004736884.1 2908033 R 63186 CDS YP_004736885.1 340618432 10978322 2908840..2909496 1 NC_015844.1 Contains a N-terminal CBS (cystathionine-beta-synthase) pair domain that can act as binding domains for adenosine derivatives such as AMP, ATP and S-AdoMet CBS domains are found attached to a wide range of other protein domains suggesting that CBS domains may play a regulatory role making proteins sensitive to adenosyl carrying ligands; Localized in the cytoplasm; Function unclear; CBS domain-containing protein 2909496 10978322 zobellia_2454 Zobellia galactanivorans CBS domain-containing protein YP_004736885.1 2908840 D 63186 CDS YP_004736886.1 340618433 10975184 2909599..2910480 1 NC_015844.1 The inorganic polyphosphate/ATP-NAD kinase or NAD(+) kinase catalyzes the phosphorylation of NAD to NADP using ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus; Belongs to the NAD kinase family; Localized in the cytoplasm; High confidence in function and specificity; NAD(+) kinase 2910480 ppnK 10975184 ppnK Zobellia galactanivorans NAD(+) kinase YP_004736886.1 2909599 D 63186 CDS YP_004736887.1 340618434 10978376 2910582..2911280 1 NC_015844.1 Signal peptide possibly cleaved between the residues 18 and 19; Putatively localized in the outer membrane; hypothetical protein 2911280 10978376 zobellia_2456 Zobellia galactanivorans hypothetical protein YP_004736887.1 2910582 D 63186 CDS YP_004736888.1 340618435 10975185 2911458..2912198 1 NC_015844.1 Undecaprenyl pyrophosphate synthetase (UPP synthetase) generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide; Belongs to the UPP synthetase family; Localized in the cytoplasm; High confidence in function and specificity; UDP pyrophosphate synthetase 2912198 uppS 10975185 uppS Zobellia galactanivorans UDP pyrophosphate synthetase YP_004736888.1 2911458 D 63186 CDS YP_004736889.1 340618436 10978730 2912203..2914815 1 NC_015844.1 This membrane protein seems involved in the insertion of outer membrane proteins. It has two domains. The C-terminal part, a beta-barrel pore-forming region inserted in the outer membrane, is a Bacterial surface antigen (D15) domain. The N-terminal part, exposed in the periplasm, and involved in gating of the pore and binding of the substrate proteins consists of four Surface antigen variable number repeats; Belongs to the surface antigen D15 family; Signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Family membership; outer membrane protein insertion porin (ompIP) family 2914815 10978730 zobellia_2458 Zobellia galactanivorans outer membrane protein insertion porin (ompIP) family YP_004736889.1 2912203 D 63186 CDS YP_004736890.1 340618437 10975186 2914907..2915728 1 NC_015844.1 Protein belonging to the skp family; Skp (OmpH) is a homotrimeric periplasmic chaperone for newly synthesised outer membrane proteins as they emerge in the periplasm from the Sec translocation machinery; Signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Family membership; outer membrane chaperone Skp family protein 2915728 10975186 zobellia_2459 Zobellia galactanivorans outer membrane chaperone Skp family protein YP_004736890.1 2914907 D 63186 CDS YP_004736891.1 340618438 10975187 2915872..2916381 1 NC_015844.1 Homotrimeric molecular chaperone that interacts specifically with newly synthesised outer membrane proteins as they emerge in the periplasm from the Sec translocation machinery, thus maintaining the solubility of early folding intermediates during passage through the periplasm; Skp must interact directly with membrane lipids and lipopolysaccharide for an efficient Skp-assisted folding of membrane proteins; Belongs to the skp family; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; High confidence in function and specificity; molecular chaperone Skp 2916381 hlpA 10975187 hlpA Zobellia galactanivorans molecular chaperone Skp YP_004736891.1 2915872 D 63186 CDS YP_004736892.1 340618439 10975190 complement(2918922..2919719) 1 NC_015844.1 Protein containing a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the outer membrane; Hypothetical protein; hypothetical protein 2919719 10975190 zobellia_2463 Zobellia galactanivorans hypothetical protein YP_004736892.1 2918922 R 63186 CDS YP_004736893.1 340618440 10975191 complement(2919820..2920686) 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases (GT2); Localized in the cytoplasm; Specificity unclear; glycosyltransferase 2920686 10975191 zobellia_2464 Zobellia galactanivorans glycosyltransferase YP_004736893.1 2919820 R 63186 CDS YP_004736894.1 340618441 10975192 complement(2920728..2921297) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 2921297 10975192 zobellia_2465 Zobellia galactanivorans hypothetical protein YP_004736894.1 2920728 R 63186 CDS YP_004736895.1 340618442 10975193 complement(2921308..2922363) 1 NC_015844.1 3-oxoacyl-[acyl-carrier-protein] synthase III, also known as beta-ketoacyl-ACP synthase III, catalyses the reaction: Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = 3-oxoacyl-[acyl-carrier-protein] + CO2 + [acyl-carrier-protein]. This is the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Its substrate specificity determines the biosynthesis of straight-chain of fatty acids instead of branched-chain. Negatively regulated by acyl-ACP, possibly by binding to either the free enzyme or the acyl-enzyme intermediate; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP synthase III 2922363 fabH3 10975193 fabH3 Zobellia galactanivorans 3-oxoacyl-ACP synthase III YP_004736895.1 2921308 R 63186 CDS YP_004736896.1 340618443 10977807 complement(2922530..2925382) 1 NC_015844.1 The P protein is the Glycine dehydrogenase [decarboxylating] of the glycine decarboxylase multienzyme complex. This glycine cleavage system, induced By glycine, catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor (Vitamin B6), carbon dioxide is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Localized in the cytoplasm; High confidence in function and specificity; glycine cleavage system, protein P component 2925382 gcvP 10977807 gcvP Zobellia galactanivorans glycine cleavage system, protein P component YP_004736896.1 2922530 R 63186 CDS YP_004736897.1 340618444 10977884 2925508..2926332 1 NC_015844.1 Contains nine transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 2926332 10977884 zobellia_2468 Zobellia galactanivorans membrane protein YP_004736897.1 2925508 D 63186 CDS YP_004736898.1 340618445 10975194 complement(2926329..2926556) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2926556 10975194 zobellia_2469 Zobellia galactanivorans hypothetical protein YP_004736898.1 2926329 R 63186 CDS YP_004736899.1 340618446 10975195 complement(2926559..2927203) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Belongs to the sigma-70 factor family, ECF subfamily; Localized in the cytoplasm; Family membership; RNA polymerase ECF-type sigma factor 2927203 10975195 zobellia_2470 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004736899.1 2926559 R 63186 CDS YP_004736900.1 340618447 10975197 2927234..2927590 1 NC_015844.1 Thiosulfate sulfurtransferase catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide; The relatively low affinity of GlpE for both thiosulfate and cyanide suggests that these compounds are not the physiological substrates. Thioredoxin 1 or related dithiol proteins could instead be the physiological sulfur-acceptor substrate; Contains one only rhodanese domain; Lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; High confidence in function and specificity; thiosulfate sulfurtransferase 2927590 glpE3 10975197 glpE3 Zobellia galactanivorans thiosulfate sulfurtransferase YP_004736900.1 2927234 D 63186 CDS YP_004736901.1 340618448 10977923 complement(2927587..2928108) 1 NC_015844.1 5'(3')-deoxyribonucleotidase dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides, with a preference for dUMP and dTMP, an intermediate activity towards dGMP, and a low activity towards dCMP and dAMP; Uses the magnesium as cofactor; Belongs to the 5'(3')-deoxyribonucleotidase family; Localized in the cytoplasm; High confidence in function and specificity; 5'(3')-deoxyribonucleotidase 2928108 10977923 zobellia_2472 Zobellia galactanivorans 5'(3')-deoxyribonucleotidase YP_004736901.1 2927587 R 63186 CDS YP_004736902.1 340618449 10975198 complement(2928356..2930374) 1 NC_015844.1 Oligopeptidase A catalyzes the hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-|-Gly-Pro-Ala is cleaved, but not Z-(Gly)5. Belongs to the family 3 of the metallopeptidases. It contains a conserved HEXXH motif that forms the active site in conjunction with a C-terminally-located Glu residue. A single zinc ion is ligated by the sidechains of the two His residues, and the more C-terminal Glu. Localized in the cytoplasm.; High confidence in function and specificity; oligopeptidase A 2930374 prlC 10975198 prlC Zobellia galactanivorans oligopeptidase A YP_004736902.1 2928356 R 63186 CDS YP_004736903.1 340618450 10978382 complement(2930397..2930798) 1 NC_015844.1 Contains three transmembrane segments and one putative EF-hand domain invoved in the calcium ion binding; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2930798 10978382 zobellia_2474 Zobellia galactanivorans hypothetical protein YP_004736903.1 2930397 R 63186 CDS YP_004736904.1 340618451 10975199 complement(2930830..2931321) 1 NC_015844.1 The N5-(carboxyamino)imidazole ribonucleotide mutase converts N5-CAIR (N5-carboxyaminoimidazole ribonucleotide) to CAIR, the sixth step of de novo purine biosynthesis. In the presence of high concentrations of bicarbonate, PurE is able to convert AIR to CAIR directly and without ATP, but in association with PurK, which possesses an ATPase activity, an enzymatic complex called Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21) is produced, converting AIR to CAIR efficiently under physiological condition; Localized in the cytoplasm; High confidence in function and specificity; N5-(carboxyamino)imidazole ribonucleotide mutase 2931321 purE 10975199 purE Zobellia galactanivorans N5-(carboxyamino)imidazole ribonucleotide mutase YP_004736904.1 2930830 R 63186 CDS YP_004736905.1 340618452 10978407 complement(2931326..2932498) 1 NC_015844.1 The N5-carboxyaminoimidazole ribonucleotide (N5_CAIR) synthetase, catalyzes the conversion of 5-aminoimidazole ribonucleotide (AIR) to N5-CAIR; It possesses an ATPase activity that is dependent on the presence of AIR (aminoimidazole ribonucleotide). The association of PurK with PurE produces an enzyme complex called Phosphoribosylaminoimidazole carboxylase (EC 4.1.1. 21) converting AIR to CAIR efficiently under physiological condition; Contains 1 ATP-grasp domain; Belongs to the PurK/PurT family; Localized in the cytoplasm; High confidence in function and specificity; N5-carboxyaminoimidazole ribonucleotide synthetase 2932498 purK 10978407 purK Zobellia galactanivorans N5-carboxyaminoimidazole ribonucleotide synthetase YP_004736905.1 2931326 R 63186 CDS YP_004736906.1 340618453 10978410 2932609..2933715 1 NC_015844.1 Bifunctional protein that contains two modules. In the N-terminal part a Hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) module, involved in the purine salvage, converts IMP to hypoxanthine and GMP to guanine. In the C-terminal part an Adenylate kinase module, involved in the energy metabolism and nucleotide synthesis, catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP to product 2 ADPs; Localized in the cytoplasm; High confidence in function and specificity; bifunctional protein Hypoxanthine-guanine phosphoribosyltransferase / adenylate kinase 2933715 hptA/adkA 10978410 hptA/adkA Zobellia galactanivorans bifunctional protein Hypoxanthine-guanine phosphoribosyltransferase / adenylate kinase YP_004736906.1 2932609 D 63186 CDS YP_004736907.1 340618454 10977992 2933901..2934902 1 NC_015844.1 Essential GTP-binding proteinputatively involved in ribosomal biogenesis; Contains two equally and highly conserved domains, an N-terminal glycine-rich domaina and a C-terminal GTP binding domain; Belongs to the GTP1/OBG family; Localized in the cytoplasm; High confidence in function and specificity; GTP-binding protein Obg 2934902 obgA 10977992 obgA Zobellia galactanivorans GTP-binding protein Obg YP_004736907.1 2933901 D 63186 CDS YP_004736908.1 340618455 10978285 2934970..2935491 1 NC_015844.1 Cotains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 2935491 10978285 zobellia_2479 Zobellia galactanivorans lipoprotein YP_004736908.1 2934970 D 63186 CDS YP_004736909.1 340618456 10975200 2935686..2936051 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 2936051 10975200 zobellia_2480 Zobellia galactanivorans hypothetical protein YP_004736909.1 2935686 D 63186 CDS YP_004736910.1 340618457 10975202 complement(2936065..2942115) 1 NC_015844.1 Contains a putative uncleavable signal sequence; hypothetical protein 2942115 10975202 zobellia_2481 Zobellia galactanivorans hypothetical protein YP_004736910.1 2936065 R 63186 CDS YP_004736911.1 340618458 10975203 complement(2942352..2943137) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 2943137 10975203 zobellia_2482 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004736911.1 2942352 R 63186 CDS YP_004736912.1 340618459 10975204 complement(2943172..2943546) 1 NC_015844.1 Protein that could be involved in the glycan degradation pathways and have a role in pathogenicity; Contains an N-terminal transmembrane segment and a C-terminal Cupin domain; Semms localized in the cytoplasmic membrane; Function unclear; hypothetical protein 2943546 10975204 zobellia_2483 Zobellia galactanivorans hypothetical protein YP_004736912.1 2943172 R 63186 CDS YP_004736913.1 340618460 10975205 complement(2943628..2945772) 1 NC_015844.1 Modular protein consisting of a N-terminal domain of unknown function, a central beta-propeller domain, encompassing four WD40 repeats, and a C-terminal OmpA domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space or outer membrane; Function unclear; OmpA-like protein 2945772 10975205 zobellia_2484 Zobellia galactanivorans OmpA-like protein YP_004736913.1 2943628 R 63186 CDS YP_004736914.1 340618461 10975206 complement(2945775..2946713) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; hypothetical protein 2946713 10975206 zobellia_2485 Zobellia galactanivorans hypothetical protein YP_004736914.1 2945775 R 63186 CDS YP_004736915.1 340618462 10975207 complement(2946717..2949602) 1 NC_015844.1 Signal peptide cleaved between the residues 28 and 29; Possibly localized in the outer membrane; hypothetical protein 2949602 10975207 zobellia_2486 Zobellia galactanivorans hypothetical protein YP_004736915.1 2946717 R 63186 CDS YP_004736916.1 340618463 10975208 2949860..2951218 1 NC_015844.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase is an enzyme involved in the biosynthesis of peptidoglycan which reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramic acid; Belongs to the MurCDEF family; Localized in the cytoplasm; High confidence in function and specificity; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 2951218 mplA 10975208 mplA Zobellia galactanivorans UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_004736916.1 2949860 D 63186 CDS YP_004736917.1 340618464 10978174 2951328..2952026 1 NC_015844.1 RadC plays a role in repair of DNA damage after UV and X-ray irradiation in prokaryotes; RadC may function specifically in recombinational repair that is associated with the replication fork. Involved in DNA repair; Localized in the cytoplasm; High confidence in function and specificity; DNA repair protein RadC 2952026 radC 10978174 radC Zobellia galactanivorans DNA repair protein RadC YP_004736917.1 2951328 D 63186 CDS YP_004736918.1 340618465 10978431 2952101..2953396 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2953396 10978431 zobellia_2489 Zobellia galactanivorans hypothetical protein YP_004736918.1 2952101 D 63186 CDS YP_004736919.1 340618466 10975209 2953389..2954078 1 NC_015844.1 Nucleotidase that shows high phosphatase activity toward three nucleoside 5'-monophosphates, UMP, dUMP, and dTMP, and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6-phosphogluconate. Is strictly specific to substrates with 5'-phosphates and shows no activity against nucleoside 2'- or 3'-monophosphates. Might be involved in the pyrimidine nucleotide substrate cycles; Uses Divalent metal cation as cofactors. Highest activity with manganese followed by magnesium and cobalt; Belongs to the HAD-like hydrolase superfamily; Localized in the cytoplasm; High confidence in function and specificity; 5'-nucleotidase 2954078 10975209 zobellia_2490 Zobellia galactanivorans 5'-nucleotidase YP_004736919.1 2953389 D 63186 CDS YP_004736920.1 340618467 10975211 2954102..2954680 1 NC_015844.1 Seems to have an uncleavable N-terminal signal sequence; Putatively localized in the cytoplasmic membrane; hypothetical protein 2954680 10975211 zobellia_2491 Zobellia galactanivorans hypothetical protein YP_004736920.1 2954102 D 63186 CDS YP_004736921.1 340618468 10975212 2954677..2956107 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 2956107 10975212 zobellia_2492 Zobellia galactanivorans periplasmic protein YP_004736921.1 2954677 D 63186 CDS YP_004736922.1 340618469 10975213 2956222..2957070 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 2957070 10975213 zobellia_2493 Zobellia galactanivorans hypothetical protein YP_004736922.1 2956222 D 63186 CDS YP_004736923.1 340618470 10975214 complement(2957067..2958344) 1 NC_015844.1 Protein possibly involved in the DNA replication or DNA repair; Contains a N-terminal AAA ATPase domain that, in general, acts as ATP-dependent protein clamps; Belongs to the AAA ATPase family that performs chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes; Localized in the cytoplasm; Specificity unclear; ATPase 2958344 10975214 zobellia_2494 Zobellia galactanivorans ATPase YP_004736923.1 2957067 R 63186 CDS YP_004736924.1 340618471 10975215 2958489..2959244 1 NC_015844.1 This family of proteins contains serine peptidases belonging to the MEROPS peptidase family S54 (clan S); They are integral membrane proteins involved in the cleavage of membrane proteins. It cleaves the transmembrane proteins within their transmembrane domains to release a soluble protein; Contains five transmembrane segments; Localized in the cytoplasmic membrane; Family membership; rhomboid-like protease, family S54 2959244 10975215 zobellia_2495 Zobellia galactanivorans rhomboid-like protease, family S54 YP_004736924.1 2958489 D 63186 CDS YP_004736925.1 340618472 10975216 complement(2959266..2960012) 1 NC_015844.1 RmlB specifically methylates the 2' hydroxy group of the ribose of guanosine 2251 in 23S rRNA, using the S-AdoMet; Contains a N-terminal RNA 2'-O ribose methyltransferase substrate binding domain and a C-terminal catalytic domain also involved in the dimer formation that adopts an alpha/beta knot fold; Belongs to the RNA methyltransferase TrmH family; Localized in the cytoplasm; High confidence in function and specificity; 23S rRNA (guanosine-2'-O-)-methyltransferase 2960012 rlmB 10975216 rlmB Zobellia galactanivorans 23S rRNA (guanosine-2'-O-)-methyltransferase YP_004736925.1 2959266 R 63186 CDS YP_004736926.1 340618473 10978468 complement(2960148..2960921) 1 NC_015844.1 Contains a lipoporotein signal peptide cleaved between the residues 23 and 24; Possibly localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2960921 10978468 zobellia_2497 Zobellia galactanivorans hypothetical protein YP_004736926.1 2960148 R 63186 CDS YP_004736927.1 340618474 10975217 complement(2960933..2962441) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 23 and 24; Localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 2962441 10975217 zobellia_2498 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736927.1 2960933 R 63186 CDS YP_004736928.1 340618475 10975218 complement(2962448..2965546) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (25-98) and the Plug module (115-224) acting as a channel gate; The signal peptide is cleaved between the residues 22 and 23; Family membership; TonB-dependent Receptor 2965546 10975218 zobellia_2499 Zobellia galactanivorans TonB-dependent Receptor YP_004736928.1 2962448 R 63186 CDS YP_004736929.1 340618476 10975219 complement(2965896..2966090) 1 NC_015844.1 Hypothetical protein; hypothetical protein 2966090 10975219 zobellia_2500 Zobellia galactanivorans hypothetical protein YP_004736929.1 2965896 R 63186 CDS YP_004736930.1 340618477 10975221 complement(2966479..2967654) 1 NC_015844.1 Contains a lipoprotein signal peptide cleaved between the residues 17 and 18; Putatively adopts a beta-helix fold; Localized in the outer membrane; Hypothetical protein; hypothetical protein 2967654 10975221 zobellia_2501 Zobellia galactanivorans hypothetical protein YP_004736930.1 2966479 R 63186 CDS YP_004736931.1 340618478 10975222 complement(2967682..2969109) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 16 and 17; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 2969109 10975222 zobellia_2502 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004736931.1 2967682 R 63186 CDS YP_004736932.1 340618479 10975223 complement(2969120..2972380) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (25-98) and the Plug module (115-241) acting as a channel gate; The signal peptide is cleaved between the residues 22 and 23; Family membership; TonB-dependent Receptor 2972380 10975223 zobellia_2503 Zobellia galactanivorans TonB-dependent Receptor YP_004736932.1 2969120 R 63186 CDS YP_004736933.1 340618480 10975224 2972538..2972651 1 NC_015844.1 Hypothetical protein; hypothetical protein 2972651 10975224 zobellia_2504 Zobellia galactanivorans hypothetical protein YP_004736933.1 2972538 D 63186 CDS YP_004736934.1 340618481 10975225 2972760..2972894 1 NC_015844.1 Contains a transmembrane segment; Possibly localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 2972894 10975225 zobellia_2505 Zobellia galactanivorans hypothetical protein YP_004736934.1 2972760 D 63186 CDS YP_004736935.1 340618482 10975226 2972984..2973442 1 NC_015844.1 Ribosomal protein S12 is one of the proteins from the 30S ribosomal subunit involved in the translation initiation step; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together; Bacterial S12 molecules contain a conserved aspartic acid residue which undergoes a post-translational beta-methylthiolation to form the corresponding 3-methylthioaspartic acid; Belongs to a family of ribosomal proteins S12p/S23e; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S12 2973442 rpsL 10975226 rpsL Zobellia galactanivorans 30S ribosomal protein S12 YP_004736935.1 2972984 D 63186 CDS YP_004736936.1 340618483 10978542 2973517..2973993 1 NC_015844.1 Ribosomal protein S7 is one of the proteins from the 30S ribosomal subunit known to bind directly to part of the 3'end of 16S ribosomal RNA where it nucleates assembly of the head domain of the 30S subunit. It is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the ribosomal protein S7p/S5e family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S7 2973993 rpsG 10978542 rpsG Zobellia galactanivorans 30S ribosomal protein S7 YP_004736936.1 2973517 D 63186 CDS YP_004736937.1 340618484 10978537 2974000..2976132 1 NC_015844.1 The Translation elongation factor G (EF-G) promotes the GTP-dependent translocation of the nascent protein chain from the A-site (acceptor site) to the P-site (peptidyl tRNA site) of the ribosome. EF-G also has a role after the termination phase of translation, where, together with the ribosomal recycling factor, it facilitates the release of tRNA and mRNA from the ribosome, and the splitting of the ribosome into two subunits; Belongs to the GTP-binding elongation factor family. EF-G/eEF-2 subfamily; Localized in the cytoplasm; High confidence in function and specificity; translation elongation factor G 2976132 fusA 10978537 fusA Zobellia galactanivorans translation elongation factor G YP_004736937.1 2974000 D 63186 CDS YP_004736938.1 340618485 10977872 2976144..2976449 1 NC_015844.1 Ribosomal protein S10 is one of the proteins from the 30S ribosomal subunit known to be involved in binding tRNA to the ribosomes; S10 has virtually no groups exposed on the ribosomal surface; Belongs to a family of ribosomal proteins S10p/S20e; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S10 2976449 rpsJ 10977872 rpsJ Zobellia galactanivorans 30S ribosomal protein S10 YP_004736938.1 2976144 D 63186 CDS YP_004736939.1 340618486 10978540 2976638..2977255 1 NC_015844.1 Ribosomal protein L3 is one of the proteins from the 50S ribosomal subunit known to bind to near the 3'end of the 23S rRNA where it nucleates assembly of the large ribosomal subunit and may participate in the formation of the peptidyltransferase center of the ribosome; Belongs to the ribosomal proteins L3p/L4e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L3 2977255 rplC 10978540 rplC Zobellia galactanivorans 50S ribosomal protein L3 YP_004736939.1 2976638 D 63186 CDS YP_004736940.1 340618487 10978495 2977255..2977884 1 NC_015844.1 One of the primary rRNA binding proteins, this protein initially binds near the 5' end of the 23S rRNA and makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. It is important during the early stages of 50S ribosomal subunit assembly and forms part of the polypeptide exit tunnel (E site); Belongs to the ribosomal protein L4b/L1a/L1e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L4 2977884 rplD 10978495 rplD Zobellia galactanivorans 50S ribosomal protein L4 YP_004736940.1 2977255 D 63186 CDS YP_004736941.1 340618488 10978496 2977891..2978181 1 NC_015844.1 Ribosomal protein L23 is one of the proteins from the 50S ribosomal subunit that binds to a specific region on the 23S rRNA; Belongs to the ribosomal protein L23p/L25e; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L23 2978181 rplW 10978496 rplW Zobellia galactanivorans 50S ribosomal protein L23 YP_004736941.1 2977891 D 63186 CDS YP_004736942.1 340618489 10978513 2978191..2979015 1 NC_015844.1 Ribosomal protein L2 is one of the proteins from the 50S ribosomal subunit; The L2 protein is located near the peptidyl transferase centre where it may contribute to peptidyltransferase activity, and is involved in the assembly of the 23SrRNA; L2 is elongated, exposing one end of the protein to the surface of the intersubunit interface of the 50 S subunit and is required for association of the 30S and 50S subunits to form the 70S ribosome; Belongs to the ribosomal proteins L2p/L8e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L2 2979015 rplB 10978513 rplB Zobellia galactanivorans 50S ribosomal protein L2 YP_004736942.1 2978191 D 63186 CDS YP_004736943.1 340618490 10978494 2979030..2979308 1 NC_015844.1 Ribosomal protein S19 is one of the proteins from the 30S ribosomal subunit known to form a complex with S13 that binds strongly to 16S ribosomal RNA. Experimental evidence has revealed that S19 is moderately exposed on the ribosomal surface and is designated a secondary rRNA binding protein; Belongs to the ribosomal protein S19p/S15e family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S19 2979308 rpsS 10978494 rpsS Zobellia galactanivorans 30S ribosomal protein S19 YP_004736943.1 2979030 D 63186 CDS YP_004736944.1 340618491 10978549 2979312..2979719 1 NC_015844.1 Ribosomal protein L22 is one of the proteins from the 50S ribosomal subunit known to bind all six domains of the 23S rRNA. Its binding is stimulated by other ribosomal proteins as L4, L17, and L20. It is important during the early stages of 50S assembly; The globular domain of the protein is located near the polypeptide exit tunnel (E site) on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome; Belongs to the ribosomal proteins L22p/L17e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L22 2979719 rplV 10978549 rplV Zobellia galactanivorans 50S ribosomal protein L22 YP_004736944.1 2979312 D 63186 CDS YP_004736945.1 340618492 10978512 2979721..2980443 1 NC_015844.1 Ribosomal protein S3 is one of the proteins from the 30S ribosomal subunit known to be involved in the binding of initiator Met-tRNA. It Binds the lower part of the 30S subunit head and the mRNA in the 70S ribosome. Forms a tight complex with proteins S10 and S14; Contains a type-2 KH domain that has been shown to bind RNA; Belongs to the ribosomal proteins S3p/S3e family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S3 2980443 rpsC 10978512 rpsC Zobellia galactanivorans 30S ribosomal protein S3 YP_004736945.1 2979721 D 63186 CDS YP_004736946.1 340618493 10978533 2980463..2980894 1 NC_015844.1 Ribosomal protein L16 is one of the proteins from the 50S ribosomal subunit known to bind directly the 23S rRNA and to be located at the A site of the peptidyltransferase center; Belongs to the ribosomal protein L16b/L10a/L10e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L16 2980894 rplP 10978533 rplP Zobellia galactanivorans 50S ribosomal protein L16 YP_004736946.1 2980463 D 63186 CDS YP_004736947.1 340618494 10978506 2980903..2981094 1 NC_015844.1 Ribosomal protein L29 is one of the proteins that surrounds the polypeptide exit tunnel on the outside of the 50S ribosomal subunit; Contacts protein L23, trigger factor and protein nascent chains; Belongs to the Ribosomal protein L29p/L35e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L29 2981094 rpmC 10978506 rpmC Zobellia galactanivorans 50S ribosomal protein L29 YP_004736947.1 2980903 D 63186 CDS YP_004736948.1 340618495 10978518 2981108..2981368 1 NC_015844.1 Ribosomal protein S17 is one of the primary rRNA binding protein from the 30S ribosomal subunit known to bind specifically to the 5' end of 16S ribosomal RNA and is thought to be involved in the recognition of termination codons. Experimental evidence has revealed that S17 has virtually no groups exposed on the ribosomal surface; Belongs to the ribosomal proteins S17p/S11e family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S17 2981368 rpsQ 10978518 rpsQ Zobellia galactanivorans 30S ribosomal protein S17 YP_004736948.1 2981108 D 63186 CDS YP_004736949.1 340618496 10978547 2981370..2981738 1 NC_015844.1 Ribosomal protein L14 is one of the proteins from the 50S ribosomal subunit known to bind directly to the 23S rRNA; Belongs to the ribosomal protein L14p/L23e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L14 2981738 rplN 10978547 rplN Zobellia galactanivorans 50S ribosomal protein L14 YP_004736949.1 2981370 D 63186 CDS YP_004736950.1 340618497 10978504 2981753..2982067 1 NC_015844.1 Ribosomal protein L24 is one of the proteins from the 50S ribosomal subunit. It is one of two assembly inititator proteins, it binds directly to the 5' end of the 23S rRNA, where it nucleates assembly of the 50S subunit and surrounds the polypeptide exit tunnel on the outside of the subunit; Contains a N-terminal KOW (Kyrpides, Ouzounis, Woese) motif involved in nucleic acid interactions; Belongs to the ribosomal proteins L24p/L26e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L24 2982067 rplX 10978504 rplX Zobellia galactanivorans 50S ribosomal protein L24 YP_004736950.1 2981753 D 63186 CDS YP_004736951.1 340618498 10978514 2982071..2982622 1 NC_015844.1 Ribosomal protein L5 is one of the proteins from the 50S ribosomal subunit that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. The 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs; In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits. This bridge is implicated in subunit movement; Contacts the P site tRNA; Belongs to the ribosomal proteins L5p/L11e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L5 2982622 rplE 10978514 rplE Zobellia galactanivorans 50S ribosomal protein L5 YP_004736951.1 2982071 D 63186 CDS YP_004736952.1 340618499 10978497 2982624..2982893 1 NC_015844.1 Ribosomal protein S14 is one of the proteins required for the assembly of the 30S ribosomal subunit and may also be responsible for determining the conformation of 16S rRNA at the A site (acceptor site); Belongs to the ribosomal proteins S14p/S29e family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S14 2982893 rpsN 10978497 rpsN Zobellia galactanivorans 30S ribosomal protein S14 YP_004736952.1 2982624 D 63186 CDS YP_004736953.1 340618500 10978544 2982960..2983358 1 NC_015844.1 Ribosomal protein S8 is one of the primary rRNA binding proteins from the 30S ribosomal subunit. It binds directly to 16S rRNA central domain where it helps to coordinate assembly of the platform of the small ribosomal subunit; Contacts proteins S5 and S12; Belongs to the ribosomal proteins S8p/S15e family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S8 2983358 rpsH 10978544 rpsH Zobellia galactanivorans 30S ribosomal protein S8 YP_004736953.1 2982960 D 63186 CDS YP_004736954.1 340618501 10978538 2983377..2983919 1 NC_015844.1 Ribosomal protein L6 is one of the proteins from the 50S ribosomal subunit known to bind directly to the 23S rRNA and is located at the aminoacyl-tRNA binding site of the peptidyltransferase center; L6 comprises 2 almost identical domains, suggesting that is was derived by the duplication of an ancient RNA-binding protein gene, the N-terminus being involved in protein-protein interactions and the C-terminus containing possible RNA-binding sites; Belongs to the ribosomal proteins L6p/L9e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L6 2983919 rplF 10978538 rplF Zobellia galactanivorans 50S ribosomal protein L6 YP_004736954.1 2983377 D 63186 CDS YP_004736955.1 340618502 10978498 2983929..2984285 1 NC_015844.1 Ribosomal protein L18 is one of the proteins from the 50S ribosomal subunit that binds and probably mediates the attachment of the 5S rRNA into the large ribosomal subunit, where it forms part of the central protuberance. It increases binding abilities of L5 in a cooperative fashion, both proteins together confering 23S rRNA binding; The protein contains a phosphoserine which is required for the binding to 5S rRNA (possibly on Ser55); Belongs to the ribosomal protein L18p/L5e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L18 2984285 rplR 10978498 rplR Zobellia galactanivorans 50S ribosomal protein L18 YP_004736955.1 2983929 D 63186 CDS YP_004736956.1 340618503 10978508 2984294..2984818 1 NC_015844.1 Ribosomal protein S5 is one of the proteins important in the assembly and function of the 30S ribosomal subunit. It is Located at the back of the small subunit body where it stabilizes the conformation of the head with respect to the body. The N-terminal domain interacts with the head of the 30S subunit, the C-terminal domain interacts with the body and contacts protein S4. With S4 and S12, S5 plays an important role in translational accuracy and the interaction surface between S4 and S5 is involved in control of translational fidelity; Contains a S5 double strand rRNA domain (dsRBD) that interacts with the 16S rRNA; Belongs to the ribosomal proteins S5p/S2e family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S5 2984818 rpsE 10978508 rpsE Zobellia galactanivorans 30S ribosomal protein S5 YP_004736956.1 2984294 D 63186 CDS YP_004736957.1 340618504 10978535 2984830..2985012 1 NC_015844.1 Ribosomal protein L30 is Localized near the guanosine triphosphatase center of the 50S subunit; Belongs to the ribosomal proteins L30p/L7e family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L30 2985012 rpmD 10978535 rpmD Zobellia galactanivorans 50S ribosomal protein L30 YP_004736957.1 2984830 D 63186 CDS YP_004736958.1 340618505 10978519 2985026..2985478 1 NC_015844.1 Ribosomal protein L15 is one of the proteins from the 50S ribosomal subunit known to bind the 23S rRNA. Belongs to the ribosomal proteins L15p/L27Ae family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L15 2985478 rplO 10978519 rplO Zobellia galactanivorans 50S ribosomal protein L15 YP_004736958.1 2985026 D 63186 CDS YP_004736959.1 340618506 10978505 2985491..2986834 1 NC_015844.1 SecY is one of seven secretory proteins (secA-F and secY) that comprise the prokaryotic protein translocation apparatus (translocase); Interacts with secA and secE to allow the translocation of proteins across the cytoplasmic membrane, by forming part of a channel; Contains 10 transmembrane segments, 6 cytoplasmic and 5 periplasmic regions; Belongs to the secY/SEC61-alpha family; Localized in the cytoplasmic membrane; High confidence in function and specificity; preprotein translocase subunit SecY 2986834 secY 10978505 secY Zobellia galactanivorans preprotein translocase subunit SecY YP_004736959.1 2985491 D 63186 CDS YP_004736960.1 340618507 10978578 2986837..2987052 1 NC_015844.1 The initiation factor IF-1 seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3. Seems stabilizes the 30S ribosomal subunit by binding to the A site. This binding may modulate subunit association and the fidelity of tRNA section in the P site through conformational changes in the 16S rRNA; Contains 1 S1-like domain found in a large number of RNA-associated proteins; Localized in the cytoplasm; High confidence in function and specificity; translation initiation factor IF-1 2987052 infA 10978578 infA Zobellia galactanivorans translation initiation factor IF-1 YP_004736960.1 2986837 D 63186 CDS YP_004736961.1 340618508 10978036 2987196..2987570 1 NC_015844.1 Ribosomal protein S13 is involved in binding fMet-tRNA. It is located at the top of the head of the 30S subunit and contacts several helices of the 16S rRNA by an N-terminal helix-two turns-helix (H2TH) domain. In the 70S ribosome, S13 contacts the 23S rRNA (bridge B1a) and protein L5 (bridge B1b), connecting the 2 subunits. These bridges are implicated in subunit movement; Forms a loose heterodimer with protein S19; Belongs to the ribosomal protein S13p/S18e; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S13 2987570 rpsM 10978036 rpsM Zobellia galactanivorans 30S ribosomal protein S13 YP_004736961.1 2987196 D 63186 CDS YP_004736962.1 340618509 10978543 2987583..2987987 1 NC_015844.1 Ribosomal protein S11 is located on the large lobe of the 30S ribosomal subunit known to plays an essential role in selecting the correct tRNA in protein biosynthesis; S11 bridges several disparate RNA helices of the 16S rRNA, forms part of the Shine-Dalgarno cleft in the 70S ribosome, interacts with proteins S7 and S18 and binds to IF-3; Belongs to the ribosomal proteins S11p/S14e family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S11 2987987 rpsK 10978543 rpsK Zobellia galactanivorans 30S ribosomal protein S11 YP_004736962.1 2987583 D 63186 CDS YP_004736963.1 340618510 10978541 2988076..2988681 1 NC_015844.1 Ribosomal protein S4 is one of the primary rRNA binding proteins from the 30S ribosomal subunit known to bind directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. With S5 and S12, S4 plays an important role in translational accuracy. The interaction surface between S4 and S5 is involved in control of translational fidelity; Belongs to the ribosomal proteins S4p/S9e; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S4 2988681 rpsD 10978541 rpsD Zobellia galactanivorans 30S ribosomal protein S4 YP_004736963.1 2988076 D 63186 CDS YP_004736964.1 340618511 10978534 2988700..2989692 1 NC_015844.1 The alpha subunit of RNA polymerase initiates the polymerase core assembly by dimerising to form a platform on which the catalytic beta and beta' and omega subunits can interact with DNA; The N-terminal domain is essential for RNA polymerase assembly and basal transcription of DNA into RNA, whereas the C-terminal domain is necessary for transcription regulation, interacting with transcription factors and promoter upstream elements; Localized in the cytoplasm; High confidence in function and specificity; DNA-dependent RNA polymerase subunit alpha 2989692 rpoA 10978534 rpoA Zobellia galactanivorans DNA-dependent RNA polymerase subunit alpha YP_004736964.1 2988700 D 63186 CDS YP_004736965.1 340618512 10978524 2989754..2990320 1 NC_015844.1 Ribosomal protein L17 is one of the proteins from the 50S ribosomal subunit; Belongs to a ribosomal proteins L17b/YmL8 (yeast) family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L17 2990320 rplQ 10978524 rplQ Zobellia galactanivorans 50S ribosomal protein L17 YP_004736965.1 2989754 D 63186 CDS YP_004736966.1 340618513 10978507 2990414..2991541 1 NC_015844.1 Carbamoyl-phosphate synthase catalyses the ATP-dependent synthesis of carbamyl-phosphate from glutamine or ammonia and bicarbonate. This important enzyme initiates both the urea cycle and the biosynthesis of arginine and/or pyrimidines. It is a heterodimer of a small and large chain. The small chain promotes the hydrolysis of glutamine to ammonia, which is used by the large chain to synthesize carbamoyl phosphate. Binds three magnesium ion as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; carbamoyl-phosphate synthase small chain 2991541 carA 10978507 carA Zobellia galactanivorans carbamoyl-phosphate synthase small chain YP_004736966.1 2990414 D 63186 CDS YP_004736967.1 340618514 10977622 2991655..2992947 1 NC_015844.1 Enolase (2-phospho-D-glycerate hydrolase) catalyzes the dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate in the ninth and penultimate step of the glycolysis (Embden-Meyerhof pathway). Enolase can also catalyze the reverse reaction, depending on environmental concentrations of substrates. It is a dimeric enzyme that requires magnesium both for catalysis and stabilizing the dimer; Localized in the cytoplasm; High confidence in function and specificity; enolase 2992947 enoA 10977622 enoA Zobellia galactanivorans enolase YP_004736967.1 2991655 D 63186 CDS YP_004736968.1 340618515 10977783 2993081..2994616 1 NC_015844.1 Bacterial glycogen synthase synthesizes alpha-1,4-glucan chains found in bacterial glycogen using ADP-glucose. Belongs to the family 5 of glycosyltransferases (GT5). Localized in the cytoplasm.; High confidence in function and specificity; glycogen synthase 2994616 glgA 10977783 glgA Zobellia galactanivorans glycogen synthase YP_004736968.1 2993081 D 63186 CDS YP_004736969.1 340618516 10977912 2994763..2996049 1 NC_015844.1 The citrate synthase is the enzyme that catalyzes an important reaction in both energy generation and carbon assimilation, the synthesis of citrate from oxaloacetate and acetyl-CoA in an aldol condensation, that is the first reaction of the tricarboxylic acid cycle (Krebs' cycle). It can directly form a carbon-carbon bond in the absence of metal ion cofactors; Allosterically inhibited by NADH; Localized in the cytoplasm; High confidence in function and specificity; citrate synthase 2996049 gltA 10977912 gltA Zobellia galactanivorans citrate synthase YP_004736969.1 2994763 D 63186 CDS YP_004736970.1 340618517 10977929 2996160..2997074 1 NC_015844.1 Protein that consists of an amidinotransferase domain; Belongs to the Dimethylarginine dimethylaminohydrolase (DdaH) family; Localized in the cytoplasm; Family membership; DdaH family protein 2997074 10977929 zobellia_2541 Zobellia galactanivorans DdaH family protein YP_004736970.1 2996160 D 63186 CDS YP_004736971.1 340618518 10975230 2997199..2998131 1 NC_015844.1 Uncharacterized protein conserved in bacteria containing a pentein-type domain of function unknown; Localized in the cytoplasm; hypothetical protein 2998131 10975230 zobellia_2542 Zobellia galactanivorans hypothetical protein YP_004736971.1 2997199 D 63186 CDS YP_004736972.1 340618519 10975231 complement(2998140..2999393) 1 NC_015844.1 Outer membrane transport protein from the OmpP1/FadL/TodX family; Signal peptide of lipoprotein cleaved between the residues 21 and 22; Localized in the outer membrane; Conserved hypothetical protein; membrane lipoprotein 2999393 10975231 zobellia_2543 Zobellia galactanivorans membrane lipoprotein YP_004736972.1 2998140 R 63186 CDS YP_004736973.1 340618520 10975232 complement(2999386..3000699) 1 NC_015844.1 Signal peptide of lipoprotein cleaved between the residues 16 and 17; Localized in the outer membrane; Conserved hypothetical protein; membrane lipoprotein 3000699 10975232 zobellia_2544 Zobellia galactanivorans membrane lipoprotein YP_004736973.1 2999386 R 63186 CDS YP_004736974.1 340618521 10975233 3000940..3001938 1 NC_015844.1 Lipoprotein that cosists of five repeats of the Kelch domain found in several eukariotic proteins; Signal peptide cleaved between the residues 23 and 24; Localized in the outer membrane; Conserved hypothetical protein; membrane lipoprotein 3001938 10975233 zobellia_2545 Zobellia galactanivorans membrane lipoprotein YP_004736974.1 3000940 D 63186 CDS YP_004736975.1 340618522 10975234 3002004..3002330 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Probably localized in the periplasmic space; hypothetical protein 3002330 10975234 zobellia_2546 Zobellia galactanivorans hypothetical protein YP_004736975.1 3002004 D 63186 CDS YP_004736976.1 340618523 10975235 3002343..3003383 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains four N-terminal transmembrane segments; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 3003383 10975235 zobellia_2547 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004736976.1 3002343 D 63186 CDS YP_004736977.1 340618524 10975236 3003386..3004120 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, that acts as transcriptional regulator; Family membership; two-component system-response regulator 3004120 10975236 zobellia_2548 Zobellia galactanivorans two-component system-response regulator YP_004736977.1 3003386 D 63186 CDS YP_004736978.1 340618525 10975237 complement(3004258..3005013) 1 NC_015844.1 Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; hypothetical protein 3005013 10975237 zobellia_2549 Zobellia galactanivorans hypothetical protein YP_004736978.1 3004258 R 63186 CDS YP_004736979.1 340618526 10975238 complement(3005010..3005690) 1 NC_015844.1 Lipoprotein that consists of a SCO1/SenC domain; Signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Family membership; membrane lipoprotein 3005690 10975238 zobellia_2550 Zobellia galactanivorans membrane lipoprotein YP_004736979.1 3005010 R 63186 CDS YP_004736980.1 340618527 10975239 complement(3005659..3006276) 1 NC_015844.1 Protein that contains five repeats of twenty aminoacids The MORN (membrane occupation and recognition nexus) repeats would contribute to the cytoplasmic membrane binding, possibly by interacting with phospholipids; Putative lipoprotein signal peptide cleaved between the residues 18 and 19; possibly localized in the outer membrane; Conserved hypothetical protein; hypothetical protein 3006276 10975239 zobellia_2551 Zobellia galactanivorans hypothetical protein YP_004736980.1 3005659 R 63186 CDS YP_004736981.1 340618528 10975240 complement(3006282..3007052) 1 NC_015844.1 Lipoprotein with a signal peptide cleaved between the residues 25 and 26; Localized in the outer memebrane; Conserved hypothetical protein; membrane lipoprotein 3007052 10975240 zobellia_2552 Zobellia galactanivorans membrane lipoprotein YP_004736981.1 3006282 R 63186 CDS YP_004736982.1 340618529 10975241 complement(3007193..3007822) 1 NC_015844.1 Contains a C-terminal transmembrane segments; Signal peptide cleaved between the residues 21 and 22; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3007822 10975241 zobellia_2553 Zobellia galactanivorans hypothetical protein YP_004736982.1 3007193 R 63186 CDS YP_004736983.1 340618530 10975242 complement(3007854..3008894) 1 NC_015844.1 Lipoprotein with a signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein; membrane lipoprotein 3008894 10975242 zobellia_2554 Zobellia galactanivorans membrane lipoprotein YP_004736983.1 3007854 R 63186 CDS YP_004736984.1 340618531 10975243 complement(3008927..3009205) 1 NC_015844.1 Protein that binds calcium ions; Contains two EF-hand domains responsible of the cooperative binding of calcium ions; Signal peptide cleaved between the residues 25 and 26; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 3009205 10975243 zobellia_2555 Zobellia galactanivorans hypothetical protein YP_004736984.1 3008927 R 63186 CDS YP_004736985.1 340618532 10975244 3009398..3010429 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains four N-terminal transmembrane segments; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 3010429 10975244 zobellia_2556 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004736985.1 3009398 D 63186 CDS YP_004736986.1 340618533 10975245 3010416..3011111 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, that acts as transcriptional regulator; Hypothetical protein; two-component system-response regulator 3011111 10975245 zobellia_2557 Zobellia galactanivorans two-component system-response regulator YP_004736986.1 3010416 D 63186 CDS YP_004736987.1 340618534 10975246 complement(3011244..3011399) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3011399 10975246 zobellia_2558 Zobellia galactanivorans hypothetical protein YP_004736987.1 3011244 R 63186 CDS YP_004736988.1 340618535 10975247 complement(3011736..3013226) 1 NC_015844.1 Permease energized by proton symporter, responsible of the high-affinity uptake of the osmoprotectant glycine betaine. Also transports dimethylsulfonioacetate and dimethylsulfoniopropionate; Contains twelve transmembrane segments; Belongs to the BCCT transporter (for Betaine / Carnitine / Choline Transporters); Localized in the cytoplasmic membrane; High confidence in function and specificity; glycine betaine transporter 3013226 opuD 10975247 opuD Zobellia galactanivorans glycine betaine transporter YP_004736988.1 3011736 R 63186 CDS YP_004736989.1 340618536 10978288 complement(3013327..3014763) 1 NC_015844.1 Protein That uses nucleotide-sugar substrates for a variety of chemical reactions using NAD as cofactor; Contains a C-terminal transmembrane segment; Localized in the cytoplasmic membrane; Specificity unclear; nucleotide-sugar epimerase-like protein 3014763 10978288 zobellia_2560 Zobellia galactanivorans nucleotide-sugar epimerase-like protein YP_004736989.1 3013327 R 63186 CDS YP_004736990.1 340618537 10975249 complement(3014779..3015204) 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 3015204 10975249 zobellia_2561 Zobellia galactanivorans hypothetical protein YP_004736990.1 3014779 R 63186 CDS YP_004736991.1 340618538 10975250 3015345..3017129 1 NC_015844.1 Arginyl-tRNA synthetase also called Arginine-tRNA ligase is a monomeric enzyme that catalyzes the transfer of arginine to specific tRNA molecule as the first step in protein biosynthesis; Belongs to the class-I aminoacyl-tRNA synthetase family; Localized in the cytoplasm; High confidence in function and specificity; arginyl-tRNA synthetase 3017129 argS 10975250 argS Zobellia galactanivorans arginyl-tRNA synthetase YP_004736991.1 3015345 D 63186 CDS YP_004736992.1 340618539 10977540 3017181..3018008 1 NC_015844.1 Contains a N-terminal transmembrane segment; Belong to the DUF (domain of unkown function) 980 family; Localized in the cytoplasmic membrane; hypothetical protein 3018008 10977540 zobellia_2563 Zobellia galactanivorans hypothetical protein YP_004736992.1 3017181 D 63186 CDS YP_004736993.1 340618540 10975251 complement(3018015..3019004) 1 NC_015844.1 Catalyzes the synthesis of D-serine from L-serine; Use the pyridoxal phosphate as cofactor (vitamin B6); Belongs to the serine/threonine dehydratase family; Localized in the cytoplasm; High confidence in function and specificity; serine racemase 3019004 SrrA 10975251 SrrA Zobellia galactanivorans serine racemase YP_004736993.1 3018015 R 63186 CDS YP_004736994.1 340618541 10978611 complement(3019054..3021573) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (100-162) and a Plug module (198-300) acting as the channel gate; The signal peptide is cleaved between the residue 26 and 27; Family membership; TonB-dependent transducer 3021573 10978611 zobellia_2565 Zobellia galactanivorans TonB-dependent transducer YP_004736994.1 3019054 R 63186 CDS YP_004736995.1 340618542 10975252 complement(3021563..3022465) 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Containe a tranmembrane segmemnt; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 3022465 10975252 zobellia_2566 Zobellia galactanivorans anti-sigma factor YP_004736995.1 3021563 R 63186 CDS YP_004736996.1 340618543 10975253 complement(3022661..3023173) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 3023173 10975253 zobellia_2567 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004736996.1 3022661 R 63186 CDS YP_004736997.1 340618544 10975254 3023283..3024656 1 NC_015844.1 Signal peptide cleaved between the residues 22 and 23; lipoprotein localized in the outer membrane; Hypothetical protein; hypothetical protein 3024656 10975254 zobellia_2568 Zobellia galactanivorans hypothetical protein YP_004736997.1 3023283 D 63186 CDS YP_004736998.1 340618545 10975255 3024830..3026167 1 NC_015844.1 The signal recognition particle (SRP) is necessary for efficient export of extra-cytoplasmic proteins. It consists of a 4.5S RNA molecule and the protein ffh. It binds to the signal peptide sequence of the protein when it emerges from the ribosomes; The Ffh protein has a two domain structure: the G-domain binds GTP and the M-domain binds the RNA and the signal peptide; Belongs to the general secretion pathway (Sec machinery); High confidence in function and specificity; signal recognition particle protein (sRP) 3026167 ffh 10975255 ffh Zobellia galactanivorans signal recognition particle protein (sRP) YP_004736998.1 3024830 D 63186 CDS YP_004736999.1 340618546 10977829 3026235..3027119 1 NC_015844.1 Bifunctional enzyme involved in the One-carbon metabolism, tetrahydrofolate pathway; FolD catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate using the NADP as coenzyme and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate; Localized in the cytoplasm; High confidence in function and specificity; bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 3027119 folD 10977829 folD Zobellia galactanivorans bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase YP_004736999.1 3026235 D 63186 CDS YP_004737000.1 340618547 10977837 3027258..3028337 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains an N- terminal PAS/PAC domain involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 3028337 10977837 zobellia_2571 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004737000.1 3027258 D 63186 CDS YP_004737001.1 340618548 10975257 3028647..3029948 1 NC_015844.1 The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; major facilitator family transporter 3029948 10975257 zobellia_2572 Zobellia galactanivorans major facilitator family transporter YP_004737001.1 3028647 D 63186 CDS YP_004737002.1 340618549 10975258 3030184..3030942 1 NC_015844.1 Protein consisting of a domain of unknown function DUF1080; Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 3030942 10975258 zobellia_2573 Zobellia galactanivorans membrane protein YP_004737002.1 3030184 D 63186 CDS YP_004737003.1 340618550 10975259 3030985..3032316 1 NC_015844.1 NAD(P)-dependent dehydrogenase that adoptd a Rossmann fold; Belongs to the GFO/IDH/MOCA family; Contains a twin-arginine translocation signal peptide cleaved between the residues 25 and 26; Localized in the periplasmic space; Specificity unclear; NAD(P)-dependent dehydrogenase 3032316 10975259 zobellia_2574 Zobellia galactanivorans NAD(P)-dependent dehydrogenase YP_004737003.1 3030985 D 63186 CDS YP_004737004.1 340618551 10975260 3032326..3033189 1 NC_015844.1 Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides; Belongs to the family 1 of the carbohydrate esterases (CE1); Signal peptide cleaved between residues 21 and 22; Localized in the periplasmic space; Specificity unclear; carbohydrate esterase 3033189 10975260 zobellia_2575 Zobellia galactanivorans carbohydrate esterase YP_004737004.1 3032326 D 63186 CDS YP_004737005.1 340618552 10975261 3033239..3034210 1 NC_015844.1 Oxidoreductase NADPH dependent; Belongs to the aldo/keto reductase 2 family; Localized in the cytoplasm; Family membership; aldo/keto reductase 3034210 10975261 zobellia_2576 Zobellia galactanivorans aldo/keto reductase YP_004737005.1 3033239 D 63186 CDS YP_004737006.1 340618553 10975262 complement(3034264..3034689) 1 NC_015844.1 Protein that consists of a glyoxalase domain; Belongs to the Glyoxalase/bleomycin resistance protein/dioxygenase superfamily, Glyoxalase/extradiol ring-cleavage dioxygenase family; Localized in the cytoplasm; Family membership; glyoxalase/extradiol ring-cleavage dioxygenase family 3034689 10975262 zobellia_2577 Zobellia galactanivorans glyoxalase/extradiol ring-cleavage dioxygenase family YP_004737006.1 3034264 R 63186 CDS YP_004737007.1 340618554 10975263 complement(3034701..3035540) 1 NC_015844.1 Hydrolase of unknown function putatively belonging to the alpha/beta hydrolase superfamily; Localized in the cytoplasm; Function unclear; hydrolase 3035540 10975263 zobellia_2578 Zobellia galactanivorans hydrolase YP_004737007.1 3034701 R 63186 CDS YP_004737008.1 340618555 10975264 complement(3035553..3036518) 1 NC_015844.1 Contains five transmembrane segments; Belongs to the DUF (domain of unknown function) 161 family; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3036518 10975264 zobellia_2579 Zobellia galactanivorans membrane protein YP_004737008.1 3035553 R 63186 CDS YP_004737009.1 340618556 10975265 complement(3036557..3037105) 1 NC_015844.1 Signal peptide of lipoprotein cleaved between the residues 16 and 17; Putatively localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3037105 10975265 zobellia_2580 Zobellia galactanivorans lipoprotein YP_004737009.1 3036557 R 63186 CDS YP_004737010.1 340618557 10975267 complement(3037154..3038656) 1 NC_015844.1 Possible ATPase; Belongs to the DUF (domain of unknown function) 853 family; Localized in the cytoplasm; Family membership; putative ATPase 3038656 10975267 zobellia_2581 Zobellia galactanivorans putative ATPase YP_004737010.1 3037154 R 63186 CDS YP_004737011.1 340618558 10975268 3038849..3039481 1 NC_015844.1 Proteins that generates a radical species by reductive cleavage of S-adenosylmethionine (SAM) through an unusual Fe-S centre; The cluster 4Fe-4S is coordinated with 3 cysteines and an exchangeable SAM; Contains a radical SAM domain; Belongs to the organic radical- activating enzymes family; Localized in the cytoplasm; Function unclear; organic radical activating protein 3039481 10975268 zobellia_2582 Zobellia galactanivorans organic radical activating protein YP_004737011.1 3038849 D 63186 CDS YP_004737012.1 340618559 10975269 complement(3039486..3040415) 1 NC_015844.1 Signal peptide of lipoprotein cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3040415 10975269 zobellia_2583 Zobellia galactanivorans lipoprotein YP_004737012.1 3039486 R 63186 CDS YP_004737013.1 340618560 10975270 complement(3040464..3041171) 1 NC_015844.1 Methyltransferases modifies DNA, RNA, proteins and small molecules for regulatory purposes using the S-adenosyl-L-methionine as coenzyme; Localized in the cytoplasm; Specificity unclear; methyltransferase 3041171 10975270 zobellia_2584 Zobellia galactanivorans methyltransferase YP_004737013.1 3040464 R 63186 CDS YP_004737014.1 340618561 10975271 3041184..3041744 1 NC_015844.1 Conserved protein belonging to the UPF0153 family. The proteins of this family contain 8 conserved cysteines that may form a metal binding site. Their function is unknown but might be an Fe-S cluster as part of an oxidoreductase complex; Localized in the cytoplasm; hypothetical protein 3041744 10975271 zobellia_2585 Zobellia galactanivorans hypothetical protein YP_004737014.1 3041184 D 63186 CDS YP_004737015.1 340618562 10975272 3041768..3042250 1 NC_015844.1 Conserved hypothetical protein distantly related to effector binding domains found in some bacterial transcriptional activators but also in DNA gyrase inhibitors; Localized in the cytoplasm; hypothetical protein 3042250 10975272 zobellia_2586 Zobellia galactanivorans hypothetical protein YP_004737015.1 3041768 D 63186 CDS YP_004737016.1 340618563 10975273 3042292..3043152 1 NC_015844.1 Protein belonging to the Fatty acid hydroxylase family; Contains four transmembrane helices; Localized in the cytoplasmic membrane.; Specificity unclear; fatty acid hydroxylase family protein 3043152 10975273 zobellia_2587 Zobellia galactanivorans fatty acid hydroxylase family protein YP_004737016.1 3042292 D 63186 CDS YP_004737017.1 340618565 10975274 complement(3043153..3044463) 1 NC_015844.1 Protein belonging to the DUF1343 family. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the cytoplasmic and/or outer membrane; Conserved hypothetical protein; lipoprotein 3044463 10975274 zobellia_2589 Zobellia galactanivorans lipoprotein YP_004737017.1 3043153 R 63186 CDS YP_004737018.1 340618564 10975276 3044413..3045654 1 NC_015844.1 Conserved membrane protein distantly related to LolC, an permease involved in the ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Features four transmembrane helices. Localized in the cytoplasmic membrane.; Family membership; membrane protein 3045654 10975276 zobellia_2588 Zobellia galactanivorans membrane protein YP_004737018.1 3044413 D 63186 CDS YP_004737019.1 340618566 10975275 3045730..3046710 1 NC_015844.1 The cysteine synthase is the enzyme responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulfide with the concomitant release of acetic acid; Uses the pyridoxal phosphate as cofactor (vitamin B6) attached to a conserved lysine residue; Belongs to the cysteine synthase/cystathionine beta-synthase family; Localized in the cytoplasm; High confidence in function and specificity; cysteine synthase A 3046710 cysK2 10975275 cysK2 Zobellia galactanivorans cysteine synthase A YP_004737019.1 3045730 D 63186 CDS YP_004737020.1 340618567 10977706 3046774..3047553 1 NC_015844.1 Enzymes that probably binds carbohydrates and that act on sugars; The protein consists to an aldose 1-epimerase domain; Its exact function is unknown; Localized in the cytoplasm; Family membership; aldose 1-epimerase family protein 3047553 10977706 zobellia_2591 Zobellia galactanivorans aldose 1-epimerase family protein YP_004737020.1 3046774 D 63186 CDS YP_004737021.1 340618568 10975278 3047563..3048195 1 NC_015844.1 This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. It displays a N-terminal cyclic nucleotide-binding domain and a C-terminal helix-turn-helix DNA-binding domain. The cyclic nucleotide-binding domain is composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure. There are six invariant amino acids in this domain, three of which are glycine residues that are thought to be essential for maintenance of the structural integrity of the beta- barrel. Localized in the cytoplasm.; Specificity unclear; catabolite gene activator 3048195 crpA2 10975278 crpA2 Zobellia galactanivorans catabolite gene activator YP_004737021.1 3047563 D 63186 CDS YP_004737022.1 340618569 10977676 3048260..3048841 1 NC_015844.1 Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership; TetR family transcriptional regulator 3048841 10977676 zobellia_2593 Zobellia galactanivorans TetR family transcriptional regulator YP_004737022.1 3048260 D 63186 CDS YP_004737023.1 340618570 10975279 3048914..3049774 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 3049774 10975279 zobellia_2594 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004737023.1 3048914 D 63186 CDS YP_004737024.1 340618571 10975280 3049888..3051060 1 NC_015844.1 Di-heme cytochrome c peroxidase (CCP) reduces hydrogen peroxide to water using c-type heme as an oxidizable substrate. However, since it possesses two, instead of one, heme prosthetic groups, CCPs reduce hydrogen peroxide without the need to generate semi-stable free radicals. The two heme groups have significantly different redox potentials. CCP is structured into two domains, each containing one c-type heme group, with a calcium-binding site at the domain interface; Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; High confidence in function and specificity; di-heme cytochrome c peroxidase 3051060 ccpA2 10975280 ccpA2 Zobellia galactanivorans di-heme cytochrome c peroxidase YP_004737024.1 3049888 D 63186 CDS YP_004737025.1 340618572 10977636 3051145..3052875 1 NC_015844.1 Sulfate transporter is a H(+)/sulfate cotransporter that may play a role in the regulation of sulfate assimilation; Contains eleven N-terminal transmembrane helices and a C-terminal STAS domain (Sulphate Transporter and AntiSigma factor antagonist) probably involved in a general NTP binding function; Belongs to the SLC26A/SulP transporter family; Localized in the cytoplasmic membrane; Specificity unclear; sulfate transporter 3052875 10977636 zobellia_2596 Zobellia galactanivorans sulfate transporter YP_004737025.1 3051145 D 63186 CDS YP_004737026.1 340618573 10975281 3053008..3054417 1 NC_015844.1 Protein with a N-terminal metallo beta-lactamase domain and two rhodanese (thiosulfate sulfurtransferase) domains: one where the active-site Cysteine residue is replaced by another aminoacid whereas the C-terminal domain displays the catalytic cysteine residue; binds two zinc ions per molecule as cofactor; Localized in the cytoplasm; Function unclear; metallo-beta-lactamase superfamily protein 3054417 10975281 zobellia_2597 Zobellia galactanivorans metallo-beta-lactamase superfamily protein YP_004737026.1 3053008 D 63186 CDS YP_004737027.1 340618574 10975282 complement(3054498..3054947) 1 NC_015844.1 localized in the cytoplasm; hypothetical protein 3054947 10975282 zobellia_2598 Zobellia galactanivorans hypothetical protein YP_004737027.1 3054498 R 63186 CDS YP_004737028.1 340618575 10975283 complement(3055285..3055479) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3055479 10975283 zobellia_2599 Zobellia galactanivorans hypothetical protein YP_004737028.1 3055285 R 63186 CDS YP_004737029.1 340618576 10975284 complement(3055451..3056983) 1 NC_015844.1 The beta-porphyranases hydrolyse the 1,4-beta-D-galactosidic linkages in porphyrans; Contains a C-terminal domain of unknown function; Belongs to the family 16 of glycoside hydrolases (GH16); Signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; High confidence in function and specificity; beta-porphyranase A 3056983 porA 10975284 porA Zobellia galactanivorans beta-porphyranase A YP_004737029.1 3055451 R 63186 CDS YP_004737030.1 340618577 10978361 complement(3057461..3058000) 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF984 family. Localized in the cytoplasm.; hypothetical protein 3058000 10978361 zobellia_2601 Zobellia galactanivorans hypothetical protein YP_004737030.1 3057461 R 63186 CDS YP_004737031.1 340618578 10975286 complement(3058324..3058416) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3058416 10975286 zobellia_2602 Zobellia galactanivorans hypothetical protein YP_004737031.1 3058324 R 63186 CDS YP_004737032.1 340618579 10975287 3058606..3058734 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3058734 10975287 zobellia_2603 Zobellia galactanivorans membrane protein YP_004737032.1 3058606 D 63186 CDS YP_004737033.1 340618580 10975288 complement(3059077..3060462) 1 NC_015844.1 Contains a N-terminal exonuclease domain found in ribonuclease T and the epsilon subunit of DNA polymerase III and, in the middle part, a GIY-YIG catalytic domain Localized in the cytoplasm; Function unclear; nuclease 3060462 10975288 zobellia_2604 Zobellia galactanivorans nuclease YP_004737033.1 3059077 R 63186 CDS YP_004737034.1 340618581 10975289 3060659..3062176 1 NC_015844.1 Conserved hypothetical protein distantly related to the Auxin-responsive GH3-like proteins; Localized in the cytoplasm; hypothetical protein 3062176 10975289 zobellia_2605 Zobellia galactanivorans hypothetical protein YP_004737034.1 3060659 D 63186 CDS YP_004737035.1 340618582 10975290 complement(3062197..3062775) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3062775 10975290 zobellia_2606 Zobellia galactanivorans hypothetical protein YP_004737035.1 3062197 R 63186 CDS YP_004737036.1 340618583 10975291 3062992..3064572 1 NC_015844.1 Contains a signal peptide cleaved between the residues 28 and 29; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3064572 10975291 zobellia_2607 Zobellia galactanivorans periplasmic protein YP_004737036.1 3062992 D 63186 CDS YP_004737037.1 340618584 10975292 3064642..3065052 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3065052 10975292 zobellia_2608 Zobellia galactanivorans hypothetical protein YP_004737037.1 3064642 D 63186 CDS YP_004737038.1 340618585 10975293 3065155..3065340 1 NC_015844.1 CsbD is a bacterial general stress response protein. Its expression is mediated by sigma-B, an alternative sigma factor. The role of CsbD in stress response is unclear. Localized in the cytoplasm.; Function unclear; CsbD-like protein 3065340 10975293 zobellia_2609 Zobellia galactanivorans CsbD-like protein YP_004737038.1 3065155 D 63186 CDS YP_004737039.1 340618586 10975294 complement(3065399..3065719) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3065719 10975294 zobellia_2610 Zobellia galactanivorans hypothetical protein YP_004737039.1 3065399 R 63186 CDS YP_004737040.1 340618587 10975296 complement(3065802..3065963) 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF1328 family. Contains two transmembrane helices; Localized in the cytoplasmic membrane; Family membership; hypothetical protein 3065963 10975296 zobellia_2611 Zobellia galactanivorans hypothetical protein YP_004737040.1 3065802 R 63186 CDS YP_004737041.1 340618588 10975297 complement(3066129..3067397) 1 NC_015844.1 Protein that Belongs to the NRAMP family (resistance-associated macrophage protein); This family of membrane proteins are divalent cation transporters; Contains 10 transmembrane segments; Possible peptide signal cleaved between the residues 25 and 26; localized in the cytoplasmic membrane; Family membership; manganese/fer transporter 3067397 10975297 zobellia_2612 Zobellia galactanivorans manganese/fer transporter YP_004737041.1 3066129 R 63186 CDS YP_004737042.1 340618589 10975298 complement(3067454..3068680) 1 NC_015844.1 Diphosphate-fructose-6-phosphate 1-phosphotransferase catalyzes the reversible phosphorylation of fructose-6-phosphate using pyrophoshate instead of ATP for phosphofructokinase (Pfk). Involved in glycolysis. It forms a homotetramer. Localized in the cytoplasm.; High confidence in function and specificity; diphosphate-fructose-6-phosphate 1-phosphotransferase 3068680 pfp 10975298 pfp Zobellia galactanivorans diphosphate-fructose-6-phosphate 1-phosphotransferase YP_004737042.1 3067454 R 63186 CDS YP_004737043.1 340618590 10978332 complement(3068699..3069739) 1 NC_015844.1 The 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP) in the Entner-Doudoroff pathway. KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources; Belongs to the Carbohydrate kinase, PfkB family, 2-dehydro-3-deoxygluconokinase (KdgK) subfamily; Localized in the cytoplasm; High confidence in function and specificity; 2-dehydro-3-deoxygluconokinase 3069739 kdgK1 10978332 kdgK1 Zobellia galactanivorans 2-dehydro-3-deoxygluconokinase YP_004737043.1 3068699 R 63186 CDS YP_004737044.1 340618591 10978053 complement(3069794..3070549) 1 NC_015844.1 The enzymes of this family are very similar and display high sequence identities, the substrate specificity is difficult to determine; A match to Glucose/ribitol dehydrogenase subfamily indicates that the protein is not an alcohol dehydrogenase, but another type of dehydrogenase or reductase; Possible signal peptide cleaved between the residues 20 and 21; Putatively localized in the periplasmic space; Family membership; acetoin(diacetyl) reductase 3070549 10978053 zobellia_2615 Zobellia galactanivorans acetoin(diacetyl) reductase YP_004737044.1 3069794 R 63186 CDS YP_004737045.1 340618592 10975299 complement(3070586..3071863) 1 NC_015844.1 The Sugar permeases belong to the major facilitator superfamily (MFS) transporters that are single-polypeptide secondary carriers capable only of transporting small solutes (probably sugars in this case) in response to chemiosmotic ion gradients; Contains 11 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; sugar permease 3071863 10975299 zobellia_2616 Zobellia galactanivorans sugar permease YP_004737045.1 3070586 R 63186 CDS YP_004737046.1 340618593 10975300 complement(3072094..3072822) 1 NC_015844.1 Transcriptional regulator involved in the repression and/or the positive regulation of genes encoding for enzymes; Contains an N-terminal HTH domain of GntR-like bacterial transcriptional regulators, involved in the binding of the protein to the operator sequences in the DNA and a C-terminal FCD domain that probably binds to a range of effector molecules that regulate the transcription of genes through the action of the N- terminal DNA-binding domain (HTH domain); Localized in the cytoplasm; Family membership; GntR family transcriptional regulator 3072822 10975300 zobellia_2617 Zobellia galactanivorans GntR family transcriptional regulator YP_004737046.1 3072094 R 63186 CDS YP_004737047.1 340618594 10975301 complement(3073064..3073987) 1 NC_015844.1 Alginate lyase catalyzes the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. It belongs to the family 7 of the polysaccharide lyases. Features a signal peptide cleaved between residues 32 and 33. Localized in the periplasm.; High confidence in function and specificity; alginate lyase 3073987 alyA2 10975301 alyA2 Zobellia galactanivorans alginate lyase YP_004737047.1 3073064 R 63186 CDS YP_004737048.1 340618595 10977512 complement(3073996..3074877) 1 NC_015844.1 Contains a N-terminal PKD domain present in the extracellular parts of proteins involved in interactions with other protein or polysaccharides and a C-terminal putative carbohydrate binding module (CBM); Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 28 and 29; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3074877 10977512 zobellia_2619 Zobellia galactanivorans lipoprotein YP_004737048.1 3073996 R 63186 CDS YP_004737049.1 340618596 10975302 complement(3074908..3076338) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane but the determination of the membrane identity for the protein localization is not clear; Family membership; SusD/RagB family lipoprotein 3076338 10975302 zobellia_2620 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737049.1 3074908 R 63186 CDS YP_004737050.1 340618597 10975304 complement(3076372..3079497) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (26-98) and the Plug module (115-224) acting as a channel gate; The signal peptide is cleaved between the residues 21 and 22; Family membership; TonB-dependent Receptor 3079497 10975304 zobellia_2621 Zobellia galactanivorans TonB-dependent Receptor YP_004737050.1 3076372 R 63186 CDS YP_004737051.1 340618598 10975305 complement(3079956..3080708) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 3080708 10975305 zobellia_2622 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004737051.1 3079956 R 63186 CDS YP_004737052.1 340618599 10975306 complement(3080714..3081064) 1 NC_015844.1 KdgF is involved in pectin degradation, but its exact function is still unknown. It adopts a Cupin beta barrel fold. Localized in the cytoplasm.; High confidence in function and specificity; pectin degradation protein KdgF 3081064 kdgF 10975306 kdgF Zobellia galactanivorans pectin degradation protein KdgF YP_004737052.1 3080714 R 63186 CDS YP_004737053.1 340618600 10978052 complement(3081074..3083329) 1 NC_015844.1 Alginate lyase catalyzes the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. It belongs to the family 17 of the polysaccharide lyases. Features an uncleaved signal peptide. Features a signal peptide cleaved between residues 25 and 26. Localized in the periplasm.; High confidence in function and specificity; alginate lyase 3083329 alyA3 10978052 alyA3 Zobellia galactanivorans alginate lyase YP_004737053.1 3081074 R 63186 CDS YP_004737054.1 340618601 10977513 complement(3083628..3083732) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3083732 10977513 zobellia_2625 Zobellia galactanivorans hypothetical protein YP_004737054.1 3083628 R 63186 CDS YP_004737055.1 340618602 10975307 3083843..3084811 1 NC_015844.1 This protein adopts a Xylose isomerase-like TIM barrel fold; Localized in the cytoplasm; Function unclear; xylose isomerase-like TIM barrel protein 3084811 10975307 zobellia_2626 Zobellia galactanivorans xylose isomerase-like TIM barrel protein YP_004737055.1 3083843 D 63186 CDS YP_004737056.1 340618603 10975308 3084834..3085562 1 NC_015844.1 Contains a Dimethylmenaquinone methyltransferase domain; Localized in the cytoplasm; hypothetical protein 3085562 10975308 zobellia_2627 Zobellia galactanivorans hypothetical protein YP_004737056.1 3084834 D 63186 CDS YP_004737057.1 340618604 10975309 complement(3085570..3086379) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3086379 10975309 zobellia_2628 Zobellia galactanivorans hypothetical protein YP_004737057.1 3085570 R 63186 CDS YP_004737058.1 340618605 10975310 complement(3086381..3086824) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3086824 10975310 zobellia_2629 Zobellia galactanivorans periplasmic protein YP_004737058.1 3086381 R 63186 CDS YP_004737059.1 340618606 10975311 complement(3086901..3088187) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain. Contains two transmembrane segments. Localized in the cytoplasmic membrane.; Specificity unclear; two-component system-sensor histidine kinase 3088187 10975311 zobellia_2630 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004737059.1 3086901 R 63186 CDS YP_004737060.1 340618607 10975312 complement(3088184..3088861) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity (here, a winged-helix DNA-binding domain) that acts as transcriptional regulator; Family membership; two-component system-response regulator 3088861 10975312 zobellia_2631 Zobellia galactanivorans two-component system-response regulator YP_004737060.1 3088184 R 63186 CDS YP_004737061.1 340618608 10975313 complement(3088962..3090641) 1 NC_015844.1 This protein would catalyse the hydrolysis of amide or amine bonds in various substrates. It adopts a classical alpha-beta TIM-barrel fold. The active site is located in the mouth of the enzyme barrel and contains a bound iron ion that coordinates a hydroxyl nucleophile; Belongs to the Amidohydrolase family; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Specificity unclear; amidohydrolase 3090641 10975313 zobellia_2632 Zobellia galactanivorans amidohydrolase YP_004737061.1 3088962 R 63186 CDS YP_004737062.1 340618609 10975314 complement(3090666..3092285) 1 NC_015844.1 Family M28 contains aminopeptidases and carboxypeptidases with two co-catalytic zinc ions (I and II). Each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. The zinc ligands occur in the sequence in the order His (II), Asp (I and II), Glu (I), Asp or Glu (II) and His (I). In addition, two other residues, an Asp and a Glu, are believed to be important for catalysis. Four of these residues occur in the motifs His-Xaa-Asp and Glu-Glu. Localized in the cytoplasm; Specificity unclear; metallopeptidase 3092285 10975314 zobellia_2633 Zobellia galactanivorans metallopeptidase YP_004737062.1 3090666 R 63186 CDS YP_004737063.1 340618610 10975315 3092740..3093681 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3093681 10975315 zobellia_2634 Zobellia galactanivorans hypothetical protein YP_004737063.1 3092740 D 63186 CDS YP_004737064.1 340618611 10975316 3093693..3094046 1 NC_015844.1 Localized cin the cytoplasm; hypothetical protein 3094046 10975316 zobellia_2635 Zobellia galactanivorans hypothetical protein YP_004737064.1 3093693 D 63186 CDS YP_004737065.1 340618613 10975317 complement(3094235..3094735) 1 NC_015844.1 Gluconokinase is involved in the gluconate catabolism pathway (Pentose phosphate pathway). It converts the D-gluconate to 6-phospho-D-gluconate; GntK adopts an alpha/beta fold, consisting of a central sheet of five parallel beta-strands flanked by alpha-helices; Belongs to the shikimate kinase family; Localized in the cytoplasm; High confidence in function and specificity; gluconokinase 3094735 gntK1 10975317 gntK1 Zobellia galactanivorans gluconokinase YP_004737065.1 3094235 R 63186 CDS YP_004737066.1 340618612 10977941 3094722..3094979 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3094979 10977941 zobellia_2636 Zobellia galactanivorans hypothetical protein YP_004737066.1 3094722 D 63186 CDS YP_004737067.1 340618614 10975318 3094990..3095991 1 NC_015844.1 The 5-dehydro-2-deoxygluconokinase catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP); Belongs to the carbohydrate kinase PfkB family, 2-dehydro-3-deoxygluconokinase (KdgK) subfamily; Localized in the cytoplasm; High confidence in function and specificity; 5-dehydro-2-deoxygluconokinase 3095991 iolC 10975318 iolC Zobellia galactanivorans 5-dehydro-2-deoxygluconokinase YP_004737067.1 3094990 D 63186 CDS YP_004737068.1 340618615 10978039 complement(3096041..3096721) 1 NC_015844.1 Possible dioxygenase involved in the cleavage of aromatic rings; Contains an N-terminal glyoxalase I domain; Belongs to the Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Localized in the cytoplasm; Function unclear; putative dioxygenase 3096721 10978039 zobellia_2639 Zobellia galactanivorans putative dioxygenase YP_004737068.1 3096041 R 63186 CDS YP_004737069.1 340618616 10975319 3096749..3096847 1 NC_015844.1 Hypothetical protein; hypothetical protein 3096847 10975319 zobellia_2640 Zobellia galactanivorans hypothetical protein YP_004737069.1 3096749 D 63186 CDS YP_004737070.1 340618617 10975321 complement(3096970..3097719) 1 NC_015844.1 Seems to contain a Carboxypeptidase-like, regulatory domain; Localized in the cytoplasm; hypothetical protein 3097719 10975321 zobellia_2641 Zobellia galactanivorans hypothetical protein YP_004737070.1 3096970 R 63186 CDS YP_004737071.1 340618618 10975322 complement(3097921..3098220) 1 NC_015844.1 Contains an N- and C-terminal transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3098220 10975322 zobellia_2642 Zobellia galactanivorans membrane protein YP_004737071.1 3097921 R 63186 CDS YP_004737072.1 340618619 10975323 complement(3098223..3098723) 1 NC_015844.1 Contains four transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3098723 10975323 zobellia_2643 Zobellia galactanivorans membrane protein YP_004737072.1 3098223 R 63186 CDS YP_004737073.1 340618620 10975324 complement(3098720..3100363) 1 NC_015844.1 Contains three central transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3100363 10975324 zobellia_2644 Zobellia galactanivorans membrane protein YP_004737073.1 3098720 R 63186 CDS YP_004737074.1 340618621 10975325 complement(3100356..3101282) 1 NC_015844.1 Contains three N-terminal and one C-terminal transmembrane segments; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3101282 10975325 zobellia_2645 Zobellia galactanivorans hypothetical protein YP_004737074.1 3100356 R 63186 CDS YP_004737075.1 340618622 10975326 complement(3101298..3102521) 1 NC_015844.1 Contains two N-terminal transmembranse segments and a C-terminal transmembranse segment; Localized in the membrane cytoplasmic; Conserved hypothetical protein; membrane protein 3102521 10975326 zobellia_2646 Zobellia galactanivorans membrane protein YP_004737075.1 3101298 R 63186 CDS YP_004737076.1 340618623 10975327 complement(3102526..3103068) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3103068 10975327 zobellia_2647 Zobellia galactanivorans hypothetical protein YP_004737076.1 3102526 R 63186 CDS YP_004737077.1 340618624 10975328 complement(3103739..3104206) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3104206 10975328 zobellia_2648 Zobellia galactanivorans hypothetical protein YP_004737077.1 3103739 R 63186 CDS YP_004737078.1 340618625 10975329 complement(3104554..3104817) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3104817 10975329 zobellia_2649 Zobellia galactanivorans membrane protein YP_004737078.1 3104554 R 63186 CDS YP_004737079.1 340618626 10975330 complement(3105100..3105738) 1 NC_015844.1 TonB is an energy-transducer for TonB-dependent receptors of Gram-negative bacteria. Energy flows from the cytoplasmic membrane into the outer membrane via a complex consisting of TonB, ExbB and ExbD proteins which are anchored in the cytoplasmic membrane. TonB interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates; Although belonging to the TonB family, this protein seems to contain a signal peptide cleaved between the residues 17 and 18, which is unsual for classical TonB proteins; Putatively localized in the periplasmic space; Specificity unclear; TonB-like protein 3105738 10975330 zobellia_2650 Zobellia galactanivorans TonB-like protein YP_004737079.1 3105100 R 63186 CDS YP_004737080.1 340618627 10975332 complement(3105946..3106776) 1 NC_015844.1 Contains two transmembrane helices in the N-terminal region. The C-terminal region is highly Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3106776 10975332 zobellia_2651 Zobellia galactanivorans membrane protein YP_004737080.1 3105946 R 63186 CDS YP_004737081.1 340618628 10975333 complement(3107110..3107310) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3107310 10975333 zobellia_2652 Zobellia galactanivorans hypothetical protein YP_004737081.1 3107110 R 63186 CDS YP_004737082.1 340618629 10975334 complement(3107270..3107368) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3107368 10975334 zobellia_2653 Zobellia galactanivorans hypothetical protein YP_004737082.1 3107270 R 63186 CDS YP_004737083.1 340618630 10975335 complement(3107938..3108234) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3108234 10975335 zobellia_2654 Zobellia galactanivorans hypothetical protein YP_004737083.1 3107938 R 63186 CDS YP_004737084.1 340618631 10975336 complement(3108215..3110227) 1 NC_015844.1 Contains an N-terminal PHP (Polymerase and Histidinol Phosphatase) domain which is a putative phosphoesterase domain and a putative C-terminal ABC (ATP-binding cassette) transporter, ABC ATPase domain; Could belong to the PHP superfamily; Localized in the cytoplasm; hypothetical protein 3110227 10975336 zobellia_2655 Zobellia galactanivorans hypothetical protein YP_004737084.1 3108215 R 63186 CDS YP_004737085.1 340618632 10975337 complement(3110540..3111505) 1 NC_015844.1 The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Localized in the cytoplasm; Function unclear; alpha/beta hydrolase-fold protein 3111505 10975337 zobellia_2656 Zobellia galactanivorans alpha/beta hydrolase-fold protein YP_004737085.1 3110540 R 63186 CDS YP_004737086.1 340618633 10975338 3111679..3111927 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3111927 10975338 zobellia_2657 Zobellia galactanivorans hypothetical protein YP_004737086.1 3111679 D 63186 CDS YP_004737087.1 340618634 10975339 3112103..3112234 1 NC_015844.1 Hypothetical protein; hypothetical protein 3112234 10975339 zobellia_2658 Zobellia galactanivorans hypothetical protein YP_004737087.1 3112103 D 63186 CDS YP_004737088.1 340618635 10975340 complement(3112259..3113671) 1 NC_015844.1 Alkaline phosphatase is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH; Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymic activity; Signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; alkaline phosphatase 3113671 PhoD2 10975340 PhoD2 Zobellia galactanivorans alkaline phosphatase YP_004737088.1 3112259 R 63186 CDS YP_004737089.1 340618636 10978348 complement(3113771..3114346) 1 NC_015844.1 [quinone]; The enzyme catalyse the NAD(P)H-dependent two-electron reductions of quinones; It apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons to protect cells against damage by free radicals and reactive oxygen species; It has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone; Uses a FAD cofactor; Localized in the cytoplasm; High confidence in function and specificity; NAD(P)H dehydrogenase 3114346 wrbA 10978348 wrbA Zobellia galactanivorans NAD(P)H dehydrogenase YP_004737089.1 3113771 R 63186 CDS YP_004737090.1 340618637 10978755 complement(3114421..3115233) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 3115233 10978755 zobellia_2661 Zobellia galactanivorans AraC family transcriptional regulator YP_004737090.1 3114421 R 63186 CDS YP_004737091.1 340618638 10975342 complement(3115247..3115630) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3115630 10975342 zobellia_2662 Zobellia galactanivorans hypothetical protein YP_004737091.1 3115247 R 63186 CDS YP_004737092.1 340618639 10975343 3116775..3119744 1 NC_015844.1 Conserved protein featuring a N-terminal conserved domain of unknown function, a central PKD domain and a C-terminal carbohydrate binding module of the family 6. Features a signal peptide cleaved between the residues 21 and 22. Localized in the periplasm.; Conserved hypothetical protein; CBM6 containing protein 3119744 10975343 zobellia_2663 Zobellia galactanivorans CBM6 containing protein YP_004737092.1 3116775 D 63186 CDS YP_004737093.1 340618640 10975344 3119897..3121840 1 NC_015844.1 This protein likely adopts a right handed parallel beta-helix fold. Displays also a C-terminal PKD domain; Signal peptide cleaved between the residues 28 and 29; Localized in the periplasmic space; Function unclear; beta-helix fold protein 3121840 10975344 zobellia_2664 Zobellia galactanivorans beta-helix fold protein YP_004737093.1 3119897 D 63186 CDS YP_004737094.1 340618641 10975345 3121912..3124650 1 NC_015844.1 Modular protein containing a N-terminal domain adopting a parallel beta-helix fold and a C-terminal carbohydrate binding module of the family 13 (CBM13). The N-terminal domain is distantly related to the polysaccharide lyases of the family 9 (PL9). Features a signal peptide cleaved between residues 26 and 27. Localized in the periplasm.; Specificity unclear; beta-helix fold protein containing CBM13 3124650 10975345 zobellia_2665 Zobellia galactanivorans beta-helix fold protein containing CBM13 YP_004737094.1 3121912 D 63186 CDS YP_004737095.1 340618642 10975346 complement(3124770..3124979) 1 NC_015844.1 Possibly localized in the cytoplasm; hypothetical protein 3124979 10975346 zobellia_2666 Zobellia galactanivorans hypothetical protein YP_004737095.1 3124770 R 63186 CDS YP_004737096.1 340618643 10975347 complement(3125073..3125306) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane.; Conserved hypothetical protein; membrane protein 3125306 10975347 zobellia_2667 Zobellia galactanivorans membrane protein YP_004737096.1 3125073 R 63186 CDS YP_004737097.1 340618644 10975348 complement(3125378..3125836) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3125836 10975348 zobellia_2668 Zobellia galactanivorans membrane protein YP_004737097.1 3125378 R 63186 CDS YP_004737098.1 340618645 10975349 complement(3125905..3126495) 1 NC_015844.1 Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership; TetR family transcriptional regulator 3126495 10975349 zobellia_2669 Zobellia galactanivorans TetR family transcriptional regulator YP_004737098.1 3125905 R 63186 CDS YP_004737099.1 340618646 10975350 3126618..3126734 1 NC_015844.1 Hypothetical protein; hypothetical protein 3126734 10975350 zobellia_2670 Zobellia galactanivorans hypothetical protein YP_004737099.1 3126618 D 63186 CDS YP_004737100.1 340618647 10975352 3126872..3128035 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 3128035 10975352 zobellia_2671 Zobellia galactanivorans AraC family transcriptional regulator YP_004737100.1 3126872 D 63186 CDS YP_004737101.1 340618648 10975353 3128278..3131355 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules (here, possibly sugars) that are too large to diffuse via the outer membrane porins or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-96), the Plug module (112-227) acting as the channel gate and a pectinesterase signature (404-423); The signal peptide is cleaved between the residue 25 and 26; Family membership; TonB-dependent Receptor 3131355 10975353 zobellia_2672 Zobellia galactanivorans TonB-dependent Receptor YP_004737101.1 3128278 D 63186 CDS YP_004737102.1 340618649 10975354 3131367..3132836 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 17 and 18; Putatively localized in the outer membrane but the determination of the membrane identity for the protein localization is not clear; Family membership; SusD/RagB family lipoprotein 3132836 10975354 zobellia_2673 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737102.1 3131367 D 63186 CDS YP_004737103.1 340618650 10975355 3132934..3134316 1 NC_015844.1 Signal peptide cleaved between the residues 23 and 24; Putatively localized in the outer membrane; Hypothetical protein; hypothetical protein 3134316 10975355 zobellia_2674 Zobellia galactanivorans hypothetical protein YP_004737103.1 3132934 D 63186 CDS YP_004737104.1 340618651 10975356 3134541..3135503 1 NC_015844.1 Enzymes that catalyze the transfer of phosphoryl group on a sugar from ATP, producing a phosphorylated sugar; Belongs to the ROK family; localized in the cytoplasm; Specificity unclear; sugar kinase 3135503 10975356 zobellia_2675 Zobellia galactanivorans sugar kinase YP_004737104.1 3134541 D 63186 CDS YP_004737105.1 340618652 10975357 3135490..3136977 1 NC_015844.1 The Sugars permeases belong to the major facilitator superfamily (MFS) transporters that are single- polypeptide secondary carriers capable only of transporting small solutes (probably sugars in this case) in response to chemiosmotic ion gradients; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; sugar permease 3136977 10975357 zobellia_2676 Zobellia galactanivorans sugar permease YP_004737105.1 3135490 D 63186 CDS YP_004737106.1 340618653 10975358 3136964..3138721 1 NC_015844.1 Sugar-phosphate isomerases are the enzyme that converts a sugar-phosphate to another sugar-phosphate. It consists of an N-terminal domain of unkown function and a C-terminal putative phosphomannose isomerase type I domain; Binds 1 zinc ion per subunit; Belongs to the the cupin superfamily, mannose-6-phosphate isomerase type 1 family; Localized in the cytoplasm; Specificity unclear; sugar-phosphate isomerase 3138721 10975358 zobellia_2677 Zobellia galactanivorans sugar-phosphate isomerase YP_004737106.1 3136964 D 63186 CDS YP_004737107.1 340618654 10975359 3138721..3139503 1 NC_015844.1 Sugar-phosphate isomerases catalyse the conversion of sugar-phosphate to another sugar-phosphate; Contains a Glucose-6-phosphate isomerase domain; Binds 1 iron ion per subunit; Belongs to the cupin superfamily, archaeal-type GPI family; Localized in the cytoplasm; Specificity unclear; sugar-phosphate isomerase 3139503 10975359 zobellia_2678 Zobellia galactanivorans sugar-phosphate isomerase YP_004737107.1 3138721 D 63186 CDS YP_004737108.1 340618655 10975360 3139560..3140960 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 14; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Family membership; sulfatase 3140960 10975360 zobellia_2679 Zobellia galactanivorans sulfatase YP_004737108.1 3139560 D 63186 CDS YP_004737109.1 340618656 10975361 3141018..3141434 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3141434 10975361 zobellia_2680 Zobellia galactanivorans membrane protein YP_004737109.1 3141018 D 63186 CDS YP_004737110.1 340618657 10975363 3141542..3143857 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-89) and the Plug module (110-221) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 3143857 10975363 zobellia_2681 Zobellia galactanivorans TonB-dependent Receptor YP_004737110.1 3141542 D 63186 CDS YP_004737111.1 340618658 10975364 3143914..3145170 1 NC_015844.1 Contains five PepSY-associated transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3145170 10975364 zobellia_2682 Zobellia galactanivorans membrane protein YP_004737111.1 3143914 D 63186 CDS YP_004737112.1 340618659 10975365 complement(3145370..3145483) 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3145483 10975365 zobellia_2683 Zobellia galactanivorans membrane protein YP_004737112.1 3145370 R 63186 CDS YP_004737113.1 340618660 10975366 3145994..3146740 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3146740 10975366 zobellia_2684 Zobellia galactanivorans hypothetical protein YP_004737113.1 3145994 D 63186 CDS YP_004737114.1 340618661 10975367 3146748..3147260 1 NC_015844.1 Belongs to the LemA family; Localized in the cytoplasm; hypothetical protein 3147260 10975367 zobellia_2685 Zobellia galactanivorans hypothetical protein YP_004737114.1 3146748 D 63186 CDS YP_004737115.1 340618662 10975368 3147265..3148461 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3148461 10975368 zobellia_2686 Zobellia galactanivorans hypothetical protein YP_004737115.1 3147265 D 63186 CDS YP_004737116.1 340618663 10975369 3148764..3148952 1 NC_015844.1 Hypothetical protein; hypothetical protein 3148952 10975369 zobellia_2687 Zobellia galactanivorans hypothetical protein YP_004737116.1 3148764 D 63186 CDS YP_004737117.1 340618664 10975370 complement(3149074..3149166) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3149166 10975370 zobellia_2688 Zobellia galactanivorans hypothetical protein YP_004737117.1 3149074 R 63186 CDS YP_004737118.1 340618665 10975371 3149444..3149773 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3149773 10975371 zobellia_2689 Zobellia galactanivorans hypothetical protein YP_004737118.1 3149444 D 63186 CDS YP_004737119.1 340618666 10975372 3149856..3150560 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3150560 10975372 zobellia_2690 Zobellia galactanivorans periplasmic protein YP_004737119.1 3149856 D 63186 CDS YP_004737120.1 340618667 10975374 3150572..3153241 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (29-112) and the Plug module (acting as a channel gate; The signal peptide is cleaved between the residues 25 and 26; Family membership; TonB-dependent Receptor 3153241 10975374 zobellia_2691 Zobellia galactanivorans TonB-dependent Receptor YP_004737120.1 3150572 D 63186 CDS YP_004737121.1 340618668 10975375 3153589..3154824 1 NC_015844.1 Integrases are tyrosine recombinases that act by catalyzing the cutting and rejoining of the recombining DNA molecules utilizing a catalytic tyrosine for the strand cleavage. The cleavage of DNA is realized by a series of staggered cuts, during which the protein becomes covalently linked to the DNA through a catalytic tyrosine residue; Contains a C-terminal Phage integrase domain; Belongs to the \\phage\\ integrase family, Tn4399-type Integrase subfamily; Localized in the cytoplasm; Family membership; Tn4399-type Integrase 3154824 10975375 zobellia_2692 Zobellia galactanivorans Tn4399-type Integrase YP_004737121.1 3153589 D 63186 CDS YP_004737122.1 340618669 10975376 3155147..3156643 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3156643 10975376 zobellia_2693 Zobellia galactanivorans hypothetical protein YP_004737122.1 3155147 D 63186 CDS YP_004737123.1 340618670 10975377 complement(3156998..3157114) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3157114 10975377 zobellia_2694 Zobellia galactanivorans hypothetical protein YP_004737123.1 3156998 R 63186 CDS YP_004737124.1 340618671 10975378 complement(3157299..3159044) 1 NC_015844.1 Contains a C-terminal transmembrane segment; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3159044 10975378 zobellia_2695 Zobellia galactanivorans hypothetical protein YP_004737124.1 3157299 R 63186 CDS YP_004737125.1 340618672 10975379 complement(3159046..3160452) 1 NC_015844.1 The Type I restriction enzyme S subunit dictates DNA sequences specificity; Contains two DNA recognition domains, each specifying recognition of one of the two defined components of the bipartite DNA target sequence; The type I restriction enzyme, M and S subunits together form a N-6 adenine methyltransferase (MTase) that methylates the amino group at the C-6 position of a adenine residue in a hemimethylated DNA recognition sequence, in order to prevent the host from digesting its own genome via its restriction enzyme; Localized in the cytoplasm; High confidence in function and specificity; type I restriction enzyme ZgaDI, S subunit 3160452 hsdS1 10975379 hsdS1 Zobellia galactanivorans type I restriction enzyme ZgaDI, S subunit YP_004737125.1 3159046 R 63186 CDS YP_004737126.1 340618673 10977998 complement(3160449..3161912) 1 NC_015844.1 The type I restriction enzyme, M and S subunits together form a N-6 adenine methyltransferase (MTase) that methylates the amino group at the C-6 position of a adenine residue in a hemimethylated bipartite DNA recognition sequence, in order to prevent the host from digesting its own genome via its restriction enzyme. It acts as a maintenance MTase modifying the DNA so that both strands become methylated. If the recognition sequence is unmethylated, in the presence of the R subunit, the complex can also act as an endonuclease, binding to the same target sequence but cutting the DNA some distance from this site; Localized in the cytoplasm; High confidence in function and specificity; type I restriction enzyme ZgaDI, M subunit 3161912 hsdM1 10977998 hsdM1 Zobellia galactanivorans type I restriction enzyme ZgaDI, M subunit YP_004737126.1 3160449 R 63186 CDS YP_004737127.1 340618674 10977994 complement(3161935..3165150) 1 NC_015844.1 The type I restriction enzyme, Subunit R recognize specific short DNA sequences and cleaves at sites remote (1000 to 5000 bp) from the recognition sequence to give random double-stranded fragments with terminal 5'-phosphates. It is required for both endonuclease and ATPase activities, but not for modification; The Type I restriction and modification enzymes are complex, multifunctional systems composed of three polypeptides R, M and S and which require ATP, S-adenosyl methionine and magnesium as cofactors. In addition to their endonucleolytic and methylase activities, they are potent DNA-dependent ATPases; The sequence recognized by ZgaDI is unknown; Localized in the cytoplasm; High confidence in function and specificity; type I restriction enzyme ZgaDI, R subunit 3165150 hsdR1 10977994 hsdR1 Zobellia galactanivorans type I restriction enzyme ZgaDI, R subunit YP_004737127.1 3161935 R 63186 CDS YP_004737128.1 340618675 10977996 3165461..3165694 1 NC_015844.1 Conserved hypothetical protein belonging to the UPF0156 family. Localized in the cytoplasm.; Family membership; hypothetical protein 3165694 10977996 zobellia_2699 Zobellia galactanivorans hypothetical protein YP_004737128.1 3165461 D 63186 CDS YP_004737129.1 340618676 10975380 complement(3166004..3166273) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3166273 10975380 zobellia_2700 Zobellia galactanivorans hypothetical protein YP_004737129.1 3166004 R 63186 CDS YP_004737130.1 340618677 10975381 complement(3166347..3167069) 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF159 family. Localized in the cytoplasm.; hypothetical protein 3167069 10975381 zobellia_2701 Zobellia galactanivorans hypothetical protein YP_004737130.1 3166347 R 63186 CDS YP_004737131.1 340618678 10975382 complement(3167276..3168211) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3168211 10975382 zobellia_2702 Zobellia galactanivorans hypothetical protein YP_004737131.1 3167276 R 63186 CDS YP_004737132.1 340618679 10975383 complement(3168451..3168684) 1 NC_015844.1 Conserved protein adopting a a ribbon-helix-helix core topology consisting of four helices in an open array of two hairpins. Such domains are found in several bacterial and phage repressors. Localized in the cytoplasm.; Family membership; Ribbon-helix-helix fold protein 3168684 10975383 zobellia_2703 Zobellia galactanivorans Ribbon-helix-helix fold protein YP_004737132.1 3168451 R 63186 CDS YP_004737133.1 340618680 10975384 complement(3168735..3169319) 1 NC_015844.1 TraA is part of a conjugative transposon and is predicted to be involved in its transfer. Belongs to the CobQ/CobB/MinD/ParA nucleotide binding protein family. Localized in the cytoplasm.; Function unclear; conjugative transposon protein TraA 3169319 traA 10975384 traA Zobellia galactanivorans conjugative transposon protein TraA YP_004737133.1 3168735 R 63186 CDS YP_004737134.1 340618681 10978677 complement(3169322..3169771) 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3169771 10978677 zobellia_2705 Zobellia galactanivorans hypothetical protein YP_004737134.1 3169322 R 63186 CDS YP_004737135.1 340618682 10975385 complement(3169774..3170625) 1 NC_015844.1 Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation; Localized in the cytoplasm; Family membership; mobilization protein mobB 3170625 mobB 10975385 mobB Zobellia galactanivorans mobilization protein mobB YP_004737135.1 3169774 R 63186 CDS YP_004737136.1 340618683 10978168 complement(3170622..3171014) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3171014 10978168 zobellia_2707 Zobellia galactanivorans hypothetical protein YP_004737136.1 3170622 R 63186 CDS YP_004737137.1 340618684 10975386 complement(3171019..3171852) 1 NC_015844.1 TraP is part of a conjugative transposon ans is predicted as a transfer primase. Contains an N-terminal CHC2 (CycHisCysCys type) zinc finger domain suggesting that this protein binds to substrates as DNA, RNA. Localized in the cytoplasm.; Function unclear; conjugative transposon proteinTraP 3171852 traP 10975386 traP Zobellia galactanivorans conjugative transposon proteinTraP YP_004737137.1 3171019 R 63186 CDS YP_004737138.1 340618685 10978684 complement(3171921..3172253) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3172253 10978684 zobellia_2709 Zobellia galactanivorans hypothetical protein YP_004737138.1 3171921 R 63186 CDS YP_004737139.1 340618686 10975387 complement(3172250..3173341) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3173341 10975387 zobellia_2710 Zobellia galactanivorans hypothetical protein YP_004737139.1 3172250 R 63186 CDS YP_004737140.1 340618687 10975389 complement(3173425..3173715) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3173715 10975389 zobellia_2711 Zobellia galactanivorans hypothetical protein YP_004737140.1 3173425 R 63186 CDS YP_004737141.1 340618688 10975390 complement(3173789..3174661) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3174661 10975390 zobellia_2712 Zobellia galactanivorans hypothetical protein YP_004737141.1 3173789 R 63186 CDS YP_004737142.1 340618689 10975391 complement(3175358..3175510) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3175510 10975391 zobellia_2713 Zobellia galactanivorans hypothetical protein YP_004737142.1 3175358 R 63186 CDS YP_004737143.1 340618690 10975392 3175556..3176761 1 NC_015844.1 The Saccharopine dehydrogenase (NADP(+), L-lysine-forming) also called Lysine-2-oxoglutarate reductase converts the N(6)-(L-1,3-dicarboxypropyl)-L-lysine (Saccharopine) to L-lysine and 2-oxoglutarate in the metabolism of lysine; Belongs to the AlaDH/PNT (Alanine dehydrogenase/Pyridine nucleotide transhydrogenase) family; Localized in the cytoplasm; High confidence in function and specificity; Saccharopine dehydrogenase 3176761 10975392 zobellia_2714 Zobellia galactanivorans Saccharopine dehydrogenase YP_004737143.1 3175556 D 63186 CDS YP_004737144.1 340618691 10975393 complement(3176844..3177956) 1 NC_015844.1 Possible phosphoesterase containing an N-terminal PHP (Polymerase and Histidinol Phosphatase) domain; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3177956 10975393 zobellia_2715 Zobellia galactanivorans periplasmic protein YP_004737144.1 3176844 R 63186 CDS YP_004737145.1 340618692 10975394 complement(3178025..3178696) 1 NC_015844.1 Contains six transmembrane segments; Belongs to the DUF (domain of unknown function) 1361 family; Localized in the cytoplasmic membrane; Family membership; membrane protein 3178696 10975394 zobellia_2716 Zobellia galactanivorans membrane protein YP_004737145.1 3178025 R 63186 CDS YP_004737146.1 340618693 10975395 3178775..3179134 1 NC_015844.1 Belongs to the DUF (domain of unknown function) 1801 family; Localized in the cytoplasm; Family membership; hypothetical protein 3179134 10975395 zobellia_2717 Zobellia galactanivorans hypothetical protein YP_004737146.1 3178775 D 63186 CDS YP_004737147.1 340618694 10975396 complement(3179135..3180724) 1 NC_015844.1 Contains 8 PepSY-associated transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3180724 10975396 zobellia_2718 Zobellia galactanivorans membrane protein YP_004737147.1 3179135 R 63186 CDS YP_004737148.1 340618695 10975397 complement(3180730..3181032) 1 NC_015844.1 Contains three transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3181032 10975397 zobellia_2719 Zobellia galactanivorans membrane protein YP_004737148.1 3180730 R 63186 CDS YP_004737149.1 340618696 10975398 complement(3181037..3181369) 1 NC_015844.1 Contains three transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3181369 10975398 zobellia_2720 Zobellia galactanivorans membrane protein YP_004737149.1 3181037 R 63186 CDS YP_004737150.1 340618697 10975400 complement(3181379..3182116) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3182116 10975400 zobellia_2721 Zobellia galactanivorans periplasmic protein YP_004737150.1 3181379 R 63186 CDS YP_004737151.1 340618698 10975401 complement(3182207..3184552) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (22-98) and the Plug module (133-232) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 3184552 10975401 zobellia_2722 Zobellia galactanivorans TonB-dependent Receptor YP_004737151.1 3182207 R 63186 CDS YP_004737152.1 340618699 10975402 3184622..3185623 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 3185623 10975402 zobellia_2723 Zobellia galactanivorans AraC family transcriptional regulator YP_004737152.1 3184622 D 63186 CDS YP_004737153.1 340618700 10975403 complement(3185635..3186456) 1 NC_015844.1 The 3-Deoxy-8-phosphooctulonate synthase is involved in the biosynthesis of KDO-8P, a precursor of lipid A; It catalyzes the aldol condensation of phosphoenolpyruvate with D-arabinose 5-phosphate, the first step in the biosynthesis of 3-deoxy-D-manno- octulosonate, part of the oligosaccharide core of lipopolysaccharide; It forms a homotrimer; Belongs to the DAHP synthetase I family; Localized in the cytoplasm; High confidence in function and specificity; 3-deoxy-8-phosphooctulonate synthase 3186456 kdsA 10975403 kdsA Zobellia galactanivorans 3-deoxy-8-phosphooctulonate synthase YP_004737153.1 3185635 R 63186 CDS YP_004737154.1 340618701 10978055 3186540..3187106 1 NC_015844.1 Signal peptide cleaved between the residues 21 and 22; Putatively localized in the outer membrane; Conserved hypothetical protein; membrane protein 3187106 10978055 zobellia_2725 Zobellia galactanivorans membrane protein YP_004737154.1 3186540 D 63186 CDS YP_004737155.1 340618702 10975404 3187228..3187767 1 NC_015844.1 Signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; Conserved hypothetical protein; membrane protein 3187767 10975404 zobellia_2726 Zobellia galactanivorans membrane protein YP_004737155.1 3187228 D 63186 CDS YP_004737156.1 340618703 10975405 3187958..3189757 1 NC_015844.1 TypA is a GTP-binding protein which undergoes tyrosine phosphorylation. Its striking sequence similarity to ribosome-binding elongation factors suggests that it uses a novel mechanism to modulate gene expression; Localized in the cytoplasm; High confidence in function and specificity; GTP-binding protein TypA 3189757 typA 10975405 typA Zobellia galactanivorans GTP-binding protein TypA YP_004737156.1 3187958 D 63186 CDS YP_004737157.1 340618704 10978716 3189851..3190768 1 NC_015844.1 Lipoprotein with a signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3190768 10978716 zobellia_2728 Zobellia galactanivorans lipoprotein YP_004737157.1 3189851 D 63186 CDS YP_004737158.1 340618705 10975406 complement(3190806..3191555) 1 NC_015844.1 Polyphosphate glucokinase catalyzes the phosphorylation of glucose using polyphosphate or ATP as the phosphoryl donor. GTP, UTP and CTP can replace ATP as phosphoryl donor; Belongs to the ROK family; Localized in the cytoplasm; High confidence in function and specificity; polyphosphate glucokinase 3191555 ppgK 10975406 ppgK Zobellia galactanivorans polyphosphate glucokinase YP_004737158.1 3190806 R 63186 CDS YP_004737159.1 340618706 10978370 complement(3191636..3193114) 1 NC_015844.1 Iduronate-2-sulfatase, called also chondroitinsulfatase is involved in the glycosaminoglycan degradation. It hydrolyzes the 2-sulfate groups from non-reducing-terminal iduronic acid residues in dermatan sulfate, heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 7; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; High confidence in function and specificity; iduronate-2-sulfatase 3193114 idsA2 10978370 idsA2 Zobellia galactanivorans iduronate-2-sulfatase YP_004737159.1 3191636 R 63186 CDS YP_004737160.1 340618707 10978025 complement(3193154..3193969) 1 NC_015844.1 Contains an N-terminal transmembrane segments and a putative C-terminal NUDIX (NUcleoside DIphosphate linked to some other moiety X) domain; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3193969 10978025 zobellia_2731 Zobellia galactanivorans membrane protein YP_004737160.1 3193154 R 63186 CDS YP_004737161.1 340618708 10975408 complement(3194063..3195148) 1 NC_015844.1 The Endonuclease/exonuclease/phosphatase domain is found in a large number of proteins including magnesium dependent endonucleases and phosphatases involved in intracellular signalling; Belongs to the Endonuclease/Exonuclease/phosphatase family; Localized in the cytoplasm; Family membership; endonuclease/exonuclease/phosphatase family protein 3195148 10975408 zobellia_2732 Zobellia galactanivorans endonuclease/exonuclease/phosphatase family protein YP_004737161.1 3194063 R 63186 CDS YP_004737162.1 340618709 10975409 complement(3195307..3195990) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasmic membrane as a peripheral membrane protein; Family membership; ABC transporter ATPase 3195990 10975409 zobellia_2733 Zobellia galactanivorans ABC transporter ATPase YP_004737162.1 3195307 R 63186 CDS YP_004737163.1 340618710 10975410 3196288..3199305 1 NC_015844.1 Protein that contains at least ten Tetratricopeptide repeat (TPR) domains involved in the proteinprotein interactions and the assembly of multiprotein complexes; Signal peptide cleavbed between the residues 21 and 22; Localized in the periplasmic space; Function unclear; hypothetical protein 3199305 10975410 zobellia_2734 Zobellia galactanivorans hypothetical protein YP_004737163.1 3196288 D 63186 CDS YP_004737164.1 340618711 10975411 3199404..3201158 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; The signal peptide is cleaved between the residues 21 and 22; Family membership; putative TonB-dependent Receptor 3201158 10975411 zobellia_2735 Zobellia galactanivorans putative TonB-dependent Receptor YP_004737164.1 3199404 D 63186 CDS YP_004737165.1 340618712 10975412 3201357..3202757 1 NC_015844.1 Lipoprotein that contains a C-terminal Cytochrome C domain using haem iron as prosthetic group; Signal peptide cleaved between the residues 15 and 16; Belongs to the monohaem c-type cytochrome family; Localized in the cytoplasmic membrane; Family membership; monoheme cytochrome c protein 3202757 10975412 zobellia_2736 Zobellia galactanivorans monoheme cytochrome c protein YP_004737165.1 3201357 D 63186 CDS YP_004737166.1 340618713 10975413 3202859..3203980 1 NC_015844.1 This conserved protein contains a N-terminal module adopting a galactose-binding domain-like fold and a C-terminal OmpA-like domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Family membership; OmpA-like periplasmic protein 3203980 10975413 zobellia_2737 Zobellia galactanivorans OmpA-like periplasmic protein YP_004737166.1 3202859 D 63186 CDS YP_004737167.1 340618714 10975414 complement(3203995..3204783) 1 NC_015844.1 Putative signal peptide cleaved between the residues 26 and 27; Possibly localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3204783 10975414 zobellia_2738 Zobellia galactanivorans periplasmic protein YP_004737167.1 3203995 R 63186 CDS YP_004737168.1 340618715 10975415 3204888..3205712 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3205712 10975415 zobellia_2739 Zobellia galactanivorans hypothetical protein YP_004737168.1 3204888 D 63186 CDS YP_004737169.1 340618716 10975416 3205779..3206210 1 NC_015844.1 Contains a signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3206210 10975416 zobellia_2740 Zobellia galactanivorans periplasmic protein YP_004737169.1 3205779 D 63186 CDS YP_004737170.1 340618717 10975418 3206286..3207905 1 NC_015844.1 This enzyme could catalyse the hydrolysis of amide or amine bonds in various substrates. This protein adopts a classical alpha-beta TIM-barrel fold. The active site is located in the mouth of the enzyme barrel and contains a bound iron ion that coordinates a hydroxyl nucleophile; Belongs to the Amidohydrolase family; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Specificity unclear; amidohydrolase 3207905 10975418 zobellia_2741 Zobellia galactanivorans amidohydrolase YP_004737170.1 3206286 D 63186 CDS YP_004737171.1 340618718 10975419 complement(3207964..3208512) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3208512 10975419 zobellia_2742 Zobellia galactanivorans periplasmic protein YP_004737171.1 3207964 R 63186 CDS YP_004737172.1 340618719 10975420 3208752..3210416 1 NC_015844.1 Asparagine synthase (glutamine-hdrolysing) catalyses the conversion of aspartate to asparagine from glutamine as amido-N-donor. Contains a N-terminal class-2 glutamine amidotransferase domain (GATase domain). Forms a homodimer. Localized in the cytoplasm.; High confidence in function and specificity; asparagine synthase B 3210416 asnB1 10975420 asnB1 Zobellia galactanivorans asparagine synthase B YP_004737172.1 3208752 D 63186 CDS YP_004737173.1 340618720 10977556 complement(3210500..3210658) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3210658 10977556 zobellia_2744 Zobellia galactanivorans hypothetical protein YP_004737173.1 3210500 R 63186 CDS YP_004737174.1 340618721 10975421 3210769..3212721 1 NC_015844.1 DNA gyrase or Topoisomerase II introduces negative supercoils into closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double- stranded DNA rings, including catenanes and knotted rings. It is a A2B2 heterotetramer, the A subunit being responsible for DNA breakage and rejoining; the B chain catalyzing ATP hydrolysis; Belongs to the type II topoisomerase family, type IIA subfamily; Localized in the cytoplasm; High confidence in function and specificity; DNA gyrase subunit B 3212721 gyrB 10975421 gyrB Zobellia galactanivorans DNA gyrase subunit B YP_004737174.1 3210769 D 63186 CDS YP_004737175.1 340618722 10977959 3212809..3212922 1 NC_015844.1 Hypothetical protein; hypothetical protein 3212922 10977959 zobellia_2746 Zobellia galactanivorans hypothetical protein YP_004737175.1 3212809 D 63186 CDS YP_004737176.1 340618723 10975422 complement(3213160..3213534) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3213534 10975422 zobellia_2747 Zobellia galactanivorans lipoprotein YP_004737176.1 3213160 R 63186 CDS YP_004737177.1 340618724 10975423 3213888..3214814 1 NC_015844.1 Malate dehydrogenases catalyse the interconversion of malate to oxaloacetate. The enzyme participates in the citric acid cycle. It uses NAD+ as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; malate dehydrogenase 3214814 mdh 10975423 mdh Zobellia galactanivorans malate dehydrogenase YP_004737177.1 3213888 D 63186 CDS YP_004737178.1 340618725 10978129 3214971..3217952 1 NC_015844.1 SecD is part of the preprotein translocase complex of type II protein secretion system. This complex comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecC, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD and SecF); Contains twelve transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; protein-export membrane protein secD 3217952 secD 10978129 secD Zobellia galactanivorans protein-export membrane protein secD YP_004737178.1 3214971 D 63186 CDS YP_004737179.1 340618726 10978576 complement(3218074..3219315) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Contains a duplicated ATPase domain; Belongs to the ABC transporter family, EF3 subfamily; Localized in the cytoplasmic membrane as a peripheral membrane protein; Family membership; ABC transporter ATPase 3219315 10978576 zobellia_2750 Zobellia galactanivorans ABC transporter ATPase YP_004737179.1 3218074 R 63186 CDS YP_004737180.1 340618727 10975425 complement(3219898..3224184) 1 NC_015844.1 Conserved protein containing C-terminal PKD repeats. Contains a prokaryotic lipoprotein signal peptide cleavage between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein; PKD repeats containing lipoprotein 3224184 10975425 zobellia_2751 Zobellia galactanivorans PKD repeats containing lipoprotein YP_004737180.1 3219898 R 63186 CDS YP_004737181.1 340618728 10975426 complement(3224460..3224978) 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 3224978 10975426 zobellia_2752 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004737181.1 3224460 R 63186 CDS YP_004737182.1 340618729 10975427 complement(3224985..3225473) 1 NC_015844.1 Conserved protein belonging to the DUF192 family. Localized in the cytoplasm.; Family membership; hypothetical protein 3225473 10975427 zobellia_2753 Zobellia galactanivorans hypothetical protein YP_004737182.1 3224985 R 63186 CDS YP_004737183.1 340618730 10975428 complement(3225572..3226534) 1 NC_015844.1 Prolipoprotein diacylglyceryl transferase catalyzes the first step in lipoprotein biogenesis, it transfers the n-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins. Features six transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; prolipoprotein diacylglyceryl transferase 3226534 lgtA 10975428 lgtA Zobellia galactanivorans prolipoprotein diacylglyceryl transferase YP_004737183.1 3225572 R 63186 CDS YP_004737184.1 340618731 10978089 complement(3226672..3226881) 1 NC_015844.1 Conserved protein belonging to the DUF37 family; Localized in the cytoplasm; Family membership; hypothetical protein 3226881 10978089 zobellia_2755 Zobellia galactanivorans hypothetical protein YP_004737184.1 3226672 R 63186 CDS YP_004737185.1 340618732 10975429 complement(3227037..3227408) 1 NC_015844.1 Conserved protein belonging to the DUF779 family. Localized in the cytoplasm.; Family membership; hypothetical protein 3227408 10975429 zobellia_2756 Zobellia galactanivorans hypothetical protein YP_004737185.1 3227037 R 63186 CDS YP_004737186.1 340618733 10975430 complement(3227410..3228930) 1 NC_015844.1 Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family; Located in the cytoplasm.; Family membership; NAD dependent aldehyde dehydrogenase 3228930 10975430 zobellia_2757 Zobellia galactanivorans NAD dependent aldehyde dehydrogenase YP_004737186.1 3227410 R 63186 CDS YP_004737187.1 340618734 10975431 3229153..3230070 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 3230070 10975431 zobellia_2758 Zobellia galactanivorans AraC family transcriptional regulator YP_004737187.1 3229153 D 63186 CDS YP_004737188.1 340618735 10975432 complement(3230084..3231562) 1 NC_015844.1 Cysteinyl-tRNA synthetase catalyzes the attachment of cysteine to its cognate transfer RNA molecule in a highly specific two-step reaction. It is a monomer and belongs to the class I of the aminoacyl-tRNA synthetases. It binds one zinc ion as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; cysteinyl-tRNA synthetase 3231562 cysS 10975432 cysS Zobellia galactanivorans cysteinyl-tRNA synthetase YP_004737188.1 3230084 R 63186 CDS YP_004737189.1 340618736 10977709 complement(3231578..3232258) 1 NC_015844.1 GTP cyclohydrolase I catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate. FolE is a homodecamer, composed of a dimer of pentamers. It is an allosteric enzyme, whose activity is modulated by K(+), divalent cations, UTP, and tetrahydrobiopterin. Tetrahydrobiopterin is an inhibitor of this enzyme. Localized in the cytoplasm.; High confidence in function and specificity; GTP cyclohydrolase I 3232258 folE1 10977709 folE1 Zobellia galactanivorans GTP cyclohydrolase I YP_004737189.1 3231578 R 63186 CDS YP_004737190.1 340618737 10977838 3232459..3234261 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3234261 10977838 zobellia_2761 Zobellia galactanivorans periplasmic protein YP_004737190.1 3232459 D 63186 CDS YP_004737191.1 340618738 10975434 3234382..3235806 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3235806 10975434 zobellia_2762 Zobellia galactanivorans periplasmic protein YP_004737191.1 3234382 D 63186 CDS YP_004737192.1 340618739 10975435 complement(3235854..3237371) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3237371 10975435 zobellia_2763 Zobellia galactanivorans periplasmic protein YP_004737192.1 3235854 R 63186 CDS YP_004737193.1 340618740 10975436 complement(3237411..3238634) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the cytoplasmic and/or outer membrane; Conserved hypothetical protein; lipoprotein 3238634 10975436 zobellia_2764 Zobellia galactanivorans lipoprotein YP_004737193.1 3237411 R 63186 CDS YP_004737194.1 340618741 10975437 3238731..3240206 1 NC_015844.1 Prolyl-tRNA synthetase catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). It forms a homodimer. Localized in the cytoplasm.; High confidence in function and specificity; prolyl-tRNA synthetase 3240206 proS 10975437 proS Zobellia galactanivorans prolyl-tRNA synthetase YP_004737194.1 3238731 D 63186 CDS YP_004737195.1 340618742 10974043 3240567..3240818 1 NC_015844.1 The ribosomal protein S20 is a part of the ribosomal small subunit. 30S ribosomal protein S20 binds directly to 16S ribosomal RNA; Belongs to the ribosomal protein S20P family; Localized in the cytoplasm; High confidence in function and specificity; 30S ribosomal protein S20 3240818 rpsT 10974043 rpsT Zobellia galactanivorans 30S ribosomal protein S20 YP_004737195.1 3240567 D 63186 CDS YP_004737196.1 340618743 10978550 complement(3240897..3241583) 1 NC_015844.1 Contains seven transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3241583 10978550 zobellia_2769 Zobellia galactanivorans membrane protein YP_004737196.1 3240897 R 63186 CDS YP_004737197.1 340618744 10975438 complement(3241616..3242377) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3242377 10975438 zobellia_2770 Zobellia galactanivorans periplasmic protein YP_004737197.1 3241616 R 63186 CDS YP_004737198.1 340618745 10975440 complement(3242648..3244321) 1 NC_015844.1 The Rho factor facilitates transcription termination by a mechanism that involves rho binding to the nascent RNA, activation of rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPAse which utilizes all four ribonucleoside triphosphates as substrates. It forms a homohexamer.; High confidence in function and specificity; transcription termination factor Rho 3244321 rho 10975440 rho Zobellia galactanivorans transcription termination factor Rho YP_004737198.1 3242648 R 63186 CDS YP_004737199.1 340618746 10978457 3244515..3244925 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3244925 10978457 zobellia_2772 Zobellia galactanivorans membrane protein YP_004737199.1 3244515 D 63186 CDS YP_004737200.1 340618747 10975441 complement(3244985..3245479) 1 NC_015844.1 Conserved protein belonging to the metallophosphoesterase family. The most conserved regions in this superfamily centre around the metal chelating residues. Localized in the cytoplasm.; Specificity unclear; metallophosphoesterase 3245479 10975441 zobellia_2773 Zobellia galactanivorans metallophosphoesterase YP_004737200.1 3244985 R 63186 CDS YP_004737201.1 340618748 10975442 3245594..3246346 1 NC_015844.1 tRNA pseudouridine synthase is responsible for the formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer-RNAs. Pseudouridine is an isomer of uridine (5-(beta-D- ribofuranosyl) uracil, and id the most abundant modified nucleoside found in all cellular RNAs. TruA contains one atom of zinc essential for its native conformation and tRNA recognition and has a strictly conserved aspartic acid that is likely to be involved in catalysis. It forms a dimer. Localized in the cytoplasm.; High confidence in function and specificity; tRNA pseudouridine synthase A 3246346 truA1 10975442 truA1 Zobellia galactanivorans tRNA pseudouridine synthase A YP_004737201.1 3245594 D 63186 CDS YP_004737202.1 340618749 10978701 3246339..3248105 1 NC_015844.1 The ABC-1 type transporters have their ABC membrane domain and their ABC ATPase domain fused in the same protein. They are involved in the efflux of compounds across the biological membranes or in targeting of membrane components; Contains six N-terminal transmembrane segments (ABC membrane) that form a pore in the cytoplasmic membrane an a C-terminal ATP-binding domain (ABC ATPase) responsible for energy generation; Belongs to the ABC-1 type transporter permease/ATP-binding family, lipid exporter subfamily (msbA subfamily); Family membership; ABC-1 type exporter ATP-binding/permease protein 3248105 10978701 zobellia_2775 Zobellia galactanivorans ABC-1 type exporter ATP-binding/permease protein YP_004737202.1 3246339 D 63186 CDS YP_004737203.1 340618750 10975443 complement(3248106..3248894) 1 NC_015844.1 The function of DUF147 family proteins is unknown, but the distribution of conserved histidines and aspartates suggests that these proteins may be metal dependent phosphoesterases. Features three transmembrane helices in the N-terminal region. Localized in the cytoplasmic membrane.; Family membership; hypothetical protein 3248894 10975443 zobellia_2776 Zobellia galactanivorans hypothetical protein YP_004737203.1 3248106 R 63186 CDS YP_004737204.1 340618751 10975444 complement(3248938..3249765) 1 NC_015844.1 Dihydropteroate synthase catalyzes the condensation of 6-hydroxymethyl-7,8-dihydropteridine pyrophosphate to para-aminobenzoic acid to form 7,8-dihydropteroate. This is the second step in the three-step pathway leading from 6-hydroxymethyl-7,8-dihydropterin to 7,8-dihydrofolate. It is implicated in resistance to sulfonamide. It forms a homodimer. Localized in the cytoplasm.; Hypothetical protein; dihydropteroate synthase 3249765 folP 10975444 folP Zobellia galactanivorans dihydropteroate synthase YP_004737204.1 3248938 R 63186 CDS YP_004737205.1 340618752 10977842 3249872..3250420 1 NC_015844.1 Conserved protein containing two consecutive domains belonging to the DUF1599 family . Localized in the cytoplasm.; Family membership; hypothetical protein 3250420 10977842 zobellia_2778 Zobellia galactanivorans hypothetical protein YP_004737205.1 3249872 D 63186 CDS YP_004737206.1 340618753 10975445 3250422..3251519 1 NC_015844.1 Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3251519 10975445 zobellia_2779 Zobellia galactanivorans membrane protein YP_004737206.1 3250422 D 63186 CDS YP_004737207.1 340618754 10975446 3251572..3252321 1 NC_015844.1 Triosephosphate isomerase (TIM) catalyzes the reversible interconversion of the dihydroxyacetone phosphate to D-glyceraldehyde 3-phosphate in the fifth step of the glycolysis (Embden-Meyerhof pathway). TIM plays an important role in several metabolic pathways and is essential for efficient energy production. It is a homodimer. A glutamic acid residue is involved in the catalytic mechanism; Localized in the cytoplasm; High confidence in function and specificity; Triosephosphate isomerase 3252321 tpiA 10975446 tpiA Zobellia galactanivorans Triosephosphate isomerase YP_004737207.1 3251572 D 63186 CDS YP_004737208.1 340618755 10978675 3252483..3253319 1 NC_015844.1 PrmA methylates ribosomal protein L11. Uses S-adenosylmethionine as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; 50S ribosomal protein L11 methyltransferase 3253319 prmA 10978675 prmA Zobellia galactanivorans 50S ribosomal protein L11 methyltransferase YP_004737208.1 3252483 D 63186 CDS YP_004737209.1 340618756 10978383 3253349..3253624 1 NC_015844.1 ClpS is involved in the modulation of the specificity of the clpAP-mediated ATP-dependent protein degradation. It binds to the N-terminal domain of the chaperone ClpA. Localized in the cytoplasm.; High confidence in function and specificity; ATP-dependent Clp protease adapter protein ClpS 3253624 clpS 10978383 clpS Zobellia galactanivorans ATP-dependent Clp protease adapter protein ClpS YP_004737209.1 3253349 D 63186 CDS YP_004737210.1 340618757 10977655 complement(3253645..3254058) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3254058 10977655 zobellia_2783 Zobellia galactanivorans membrane protein YP_004737210.1 3253645 R 63186 CDS YP_004737211.1 340618758 10975448 complement(3254058..3254618) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3254618 10975448 zobellia_2784 Zobellia galactanivorans membrane protein YP_004737211.1 3254058 R 63186 CDS YP_004737212.1 340618759 10975449 3254783..3255136 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3255136 10975449 zobellia_2785 Zobellia galactanivorans hypothetical protein YP_004737212.1 3254783 D 63186 CDS YP_004737213.1 340618760 10975450 3255123..3256109 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to family 12 of transposases; Localized in the cytoplasm; Family membership; transposase, family 12 3256109 10975450 zobellia_2786 Zobellia galactanivorans transposase, family 12 YP_004737213.1 3255123 D 63186 CDS YP_004737214.1 340618761 10975451 3256119..3256214 1 NC_015844.1 Hypothetical protein; hypothetical protein 3256214 10975451 zobellia_2787 Zobellia galactanivorans hypothetical protein YP_004737214.1 3256119 D 63186 CDS YP_004737215.1 340618762 10974044 3256416..3256928 1 NC_015844.1 Adenine phosphoribosyltransferase catalyzes a purine salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. Forms a homodimer. Localized in the cytoplasm.; High confidence in function and specificity; adenine phosphoribosyltransferase 3256928 apt 10974044 apt Zobellia galactanivorans adenine phosphoribosyltransferase YP_004737215.1 3256416 D 63186 CDS YP_004737216.1 340618763 10977526 3257633..3258571 1 NC_015844.1 Conserved protein belonging to the Sodium/calcium exchanger family. These permeases regulate intracellular Ca2+ concentrations. Features ten transmembrane helices. Localized in the cytoplasmic membrane.; Family membership; sodium/calcium exchanger 3258571 10977526 zobellia_2790 Zobellia galactanivorans sodium/calcium exchanger YP_004737216.1 3257633 D 63186 CDS YP_004737217.1 340618764 10975454 complement(3258899..3259915) 1 NC_015844.1 Glutamine synthetase (GS), also known as Glutamate-ammonia ligase, plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. Belongs to the GS class II which is usually found in eukaryotes and in bacteria belonging to the Rhizobiaceae, Frankiaceae, and Streptomycetaceae families. GSII are octamer of identical subunits. Localized in the cytoplasm.; High confidence in function and specificity; glutamine synthetase II 3259915 glnII 10975454 glnII Zobellia galactanivorans glutamine synthetase II YP_004737217.1 3258899 R 63186 CDS YP_004737218.1 340618765 10977918 3260127..3262313 1 NC_015844.1 Glutamine synthetase (GS), also known as Glutamate-ammonia ligase, plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine. Belongs to the GS class III which includes GS from Bacteroides fragilis and Butyrivibrio fibrisolvens. GSIII enzymes are much larger (about 700 amino acids) than the GSI (450 to 470 amino acids) or GSII (350 to 420 amino acids) enzymes. It forms a hexamer. Localized in the cytoplasm.; High confidence in function and specificity; glutamine synthetase 3262313 glnA 10977918 glnA Zobellia galactanivorans glutamine synthetase YP_004737218.1 3260127 D 63186 CDS YP_004737219.1 340618766 10977916 3262433..3263281 1 NC_015844.1 Contains a signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3263281 10977916 zobellia_2793 Zobellia galactanivorans periplasmic protein YP_004737219.1 3262433 D 63186 CDS YP_004737220.1 340618767 10975455 3263366..3264547 1 NC_015844.1 Phosphoribosylformylglycinamidine cyclo-ligase is involved in purine biosynthesis. It catalyzes the reaction: ATP + 2-(formamido)-N1-(5-phospho-D- ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. Localized in the cytoplasm.; High confidence in function and specificity; phosphoribosylformylglycinamidine cyclo-ligase 3264547 purM 10975455 purM Zobellia galactanivorans phosphoribosylformylglycinamidine cyclo-ligase YP_004737220.1 3263366 D 63186 CDS YP_004737221.1 340618768 10978412 3264598..3265047 1 NC_015844.1 Protein that contains an unknown function N-terminal domain and a C-terminal Rieske [2Fe-2S] domain; The rieske domain has a [2Fe-2S] centre. Two conserved cysteines that one Fe ion while the other Fe ion is coordinated by two conserved histidines; Prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Function unclear; Rieske [2Fe-2S] iron-sulfur protein 3265047 10978412 zobellia_2795 Zobellia galactanivorans Rieske [2Fe-2S] iron-sulfur protein YP_004737221.1 3264598 D 63186 CDS YP_004737222.1 340618769 10975456 3265076..3265507 1 NC_015844.1 Conserved protein belonging to the thioredoxin family. Thioredoxins are small proteins of approximately one hundred amino-acid residues which participate in various redox reactions via the reversible oxidation of an active center disulfide bond. Features a signal peptide cleaved between the residues 21 and 22. Localized in the periplasm.; Family membership; thioredoxin family protein 3265507 10975456 zobellia_2796 Zobellia galactanivorans thioredoxin family protein YP_004737222.1 3265076 D 63186 CDS YP_004737223.1 340618770 10975457 3265508..3266497 1 NC_015844.1 ApbE is involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine (HMP) moiety of thiamine. Localized in the cytoplasm.; High confidence in function and specificity; thiamine biosynthesis protein apbE 3266497 apbE2 10975457 apbE2 Zobellia galactanivorans thiamine biosynthesis protein apbE YP_004737223.1 3265508 D 63186 CDS YP_004737224.1 340618771 10977524 3266593..3267669 1 NC_015844.1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. It possess a peptidyl-tRNA hydrolase activity. Localized in the cytoplasm.; High confidence in function and specificity; peptide chain release factor 1 3267669 prfA 10977524 prfA Zobellia galactanivorans peptide chain release factor 1 YP_004737224.1 3266593 D 63186 CDS YP_004737225.1 340618772 10978378 3267715..3268524 1 NC_015844.1 Orotidine 5'-phosphate decarboxylase catalyzes the last step in the de novo biosynthesis of pyrimidines, the decarboxylation of Orotidine 5'-phosphate into UMP. Localized in the cytoplasm.; High confidence in function and specificity; orotidine 5'-phosphate decarboxylase 3268524 pyrF 10978378 pyrF Zobellia galactanivorans orotidine 5'-phosphate decarboxylase YP_004737225.1 3267715 D 63186 CDS YP_004737226.1 340618773 10978421 complement(3268537..3268641) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3268641 10978421 zobellia_2800 Zobellia galactanivorans hypothetical protein YP_004737226.1 3268537 R 63186 CDS YP_004737227.1 340618774 10975460 3269121..3269912 1 NC_015844.1 The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices Belongs to alpha/beta hydrolase superfamily; Contains a central transmembrane segment delimiting a cytoplasmic N-terminal part and a periplasmic C-terminal part; Localized in the cytoplasmic membrane; Function unclear; alpha/beta hydrolase-fold protein 3269912 10975460 zobellia_2801 Zobellia galactanivorans alpha/beta hydrolase-fold protein YP_004737227.1 3269121 D 63186 CDS YP_004737228.1 340618775 10975461 3269921..3270016 1 NC_015844.1 Hypothetical protein; hypothetical protein 3270016 10975461 zobellia_2802 Zobellia galactanivorans hypothetical protein YP_004737228.1 3269921 D 63186 CDS YP_004737229.1 340618776 10975462 complement(3270172..3270876) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the cytoplasmic and/or outer membrane; Conserved hypothetical protein; lipoprotein 3270876 10975462 zobellia_2803 Zobellia galactanivorans lipoprotein YP_004737229.1 3270172 R 63186 CDS YP_004737230.1 340618777 10975463 complement(3270962..3271813) 1 NC_015844.1 Formyltetrahydrofolate deformylase produces formate from formyl-tetrahydrofolate. Provides the major source of formate for the purT-dependent synthesis of 5'-phosphoribosyl-N-formylglycinamide during aerobic growth. Has a role in regulating the one-carbon pool. purU forms a hexamer and is localized in the cytoplasm.; High confidence in function and specificity; formyltetrahydrofolate deformylase 3271813 purU 10975463 purU Zobellia galactanivorans formyltetrahydrofolate deformylase YP_004737230.1 3270962 R 63186 CDS YP_004737231.1 340618778 10978414 complement(3271902..3272315) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3272315 10978414 zobellia_2805 Zobellia galactanivorans hypothetical protein YP_004737231.1 3271902 R 63186 CDS YP_004737232.1 340618779 10975464 3272442..3272888 1 NC_015844.1 The AsnC/Lrp-type transcriptional regulator family appears to be an important regulatory system of the amino acid metabolism and related processes; Contains a N-terminal DNA binding AsnC/Lrp-type HTH domain. The C-terminal part contains an effector-binding domain and/or an oligomerization domain; Localized in the cytoplasm; Family membership; AsnC/Lrp-type transcriptional regulator 3272888 10975464 zobellia_2806 Zobellia galactanivorans AsnC/Lrp-type transcriptional regulator YP_004737232.1 3272442 D 63186 CDS YP_004737233.1 340618780 10975465 3272995..3275064 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3275064 10975465 zobellia_2807 Zobellia galactanivorans periplasmic protein YP_004737233.1 3272995 D 63186 CDS YP_004737234.1 340618781 10975466 3275170..3275994 1 NC_015844.1 Mechanosensitive channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation; Contains three transmembrane helices; Belongs to the small-conductance MS channels; Localized in the cytoplasmic membrane; Specificity unclear; small-conductance mechanosensitive channel 3275994 10975466 zobellia_2808 Zobellia galactanivorans small-conductance mechanosensitive channel YP_004737234.1 3275170 D 63186 CDS YP_004737235.1 340618782 10975467 3276074..3277486 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3277486 10975467 zobellia_2809 Zobellia galactanivorans lipoprotein YP_004737235.1 3276074 D 63186 CDS YP_004737236.1 340618783 10975468 complement(3277492..3278229) 1 NC_015844.1 Protein belonging to the family 56 of the cysteine peptidases (C56), but lacks the catalytic diad Cys-His; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Function unclear; family C56 non-peptidase protein 3278229 10975468 zobellia_2810 Zobellia galactanivorans family C56 non-peptidase protein YP_004737236.1 3277492 R 63186 CDS YP_004737237.1 340618784 10975470 3278314..3278964 1 NC_015844.1 Protein containing a domain of unknown function DUF 1684; Localized in the cytoplasm; Family membership; hypothetical protein 3278964 10975470 zobellia_2811 Zobellia galactanivorans hypothetical protein YP_004737237.1 3278314 D 63186 CDS YP_004737238.1 340618785 10975471 complement(3279042..3280109) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 28 and 29; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3280109 10975471 zobellia_2812 Zobellia galactanivorans periplasmic protein YP_004737238.1 3279042 R 63186 CDS YP_004737239.1 340618786 10975472 complement(3280224..3281456) 1 NC_015844.1 AmtB is a membrane channel involved in the uptake of ammonia (NH4+). It forms a homotrimer and the monomeric subunit features eleven transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; ammonia channel 3281456 amtB 10975472 amtB Zobellia galactanivorans ammonia channel YP_004737239.1 3280224 R 63186 CDS YP_004737240.1 340618787 10977520 complement(3281484..3281822) 1 NC_015844.1 P-II indirectly controls the transcription of the glutamine synthetase gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by glnE, so activating the enzyme; Forms a homotrimer; Localized in the cytoplasm; High confidence in function and specificity; nitrogen regulatory protein P-II 3281822 glnB 10977520 glnB Zobellia galactanivorans nitrogen regulatory protein P-II YP_004737240.1 3281484 R 63186 CDS YP_004737241.1 340618788 10977917 3281853..3281984 1 NC_015844.1 Hypothetical protein; hypothetical protein 3281984 10977917 zobellia_2815 Zobellia galactanivorans hypothetical protein YP_004737241.1 3281853 D 63186 CDS YP_004737242.1 340618789 10975473 complement(3282115..3282486) 1 NC_015844.1 The exact function of CrcB is not known. But its overproduction leads to camphor resistance and chromosome condensation. Its deletion increases sensibility to nucleoid decondensation. Probably interacts with the heat-shock protein cspE, possibly providing a way to anchor the chromosome to the membrane. Features four transmembrane helices. Localized in the cytoplasmic membrane.; Function unclear; protein CrcB 3282486 crcB 10975473 crcB Zobellia galactanivorans protein CrcB YP_004737242.1 3282115 R 63186 CDS YP_004737243.1 340618790 10977674 3282970..3283098 1 NC_015844.1 Hypothetical protein; hypothetical protein 3283098 10977674 zobellia_2817 Zobellia galactanivorans hypothetical protein YP_004737243.1 3282970 D 63186 CDS YP_004737244.1 340618791 10975474 3283095..3283481 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3283481 10975474 zobellia_2818 Zobellia galactanivorans hypothetical protein YP_004737244.1 3283095 D 63186 CDS YP_004737245.1 340618792 10975475 complement(3283585..3284649) 1 NC_015844.1 Branched-chain-amino-acid aminotransferase is involved in leucine, isoleucine and valine biosynthesis from L-glutamic acid; It forms a homohexamer and used one Pyridoxal phosphate as cofactor per subunit; Belongs to the Aminotransferase class IV; Localized in the cytoplasm; High confidence in function and specificity; branched-chain-amino-acid aminotransferase 3284649 ilvE 10975475 ilvE Zobellia galactanivorans branched-chain-amino-acid aminotransferase YP_004737245.1 3283585 R 63186 CDS YP_004737246.1 340618793 10978034 3284755..3285249 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 3285249 10978034 zobellia_2820 Zobellia galactanivorans membrane protein YP_004737246.1 3284755 D 63186 CDS YP_004737247.1 340618794 10975477 3285251..3285910 1 NC_015844.1 Conserved protein belonging to the DUF752 family. Localized in the cytoplasm.; Conserved hypothetical protein; hypothetical protein 3285910 10975477 zobellia_2821 Zobellia galactanivorans hypothetical protein YP_004737247.1 3285251 D 63186 CDS YP_004737248.1 340618795 10975478 3286038..3287003 1 NC_015844.1 Conserved protein belonging to the NAD(P)-dependent epimerase/dehydratase family. Adopts a Rossmann fold. Localized in the cytoplasm.; Function unclear; NAD(P)-dependent epimerase/dehydratase 3287003 10975478 zobellia_2822 Zobellia galactanivorans NAD(P)-dependent epimerase/dehydratase YP_004737248.1 3286038 D 63186 CDS YP_004737249.1 340618796 10975479 3287206..3287769 1 NC_015844.1 Dimeric GrpE is a co-chaperone for the molecular chaperone DnaK. Acts as a nucleotide exchange factor and may function as a thermosensor; High confidence in function and specificity; Co-chaperone HSP-70 protein 3287769 grpE 10975479 grpE Zobellia galactanivorans Co-chaperone HSP-70 protein YP_004737249.1 3287206 D 63186 CDS YP_004737250.1 340618797 10977953 3287779..3288897 1 NC_015844.1 DnaJ is a molecular co-chaperone for the molecular chperone DnaK; Besides stimulating the ATPase activity of DnaK through its N-terminal J-domain, DnaJ also associates with unfolded polypeptide chains and prevents their aggregation; DnaJ has been shown to bind both L- and D-peptides and is assumed to interact only with the side chains of the substrate. Contains a N-terminal J-domain (interaction with DnaK), a C-terminal domain (unknown function) and a central cystein rich module; High confidence in function and specificity; Co-chaperone protein dnaJ 3288897 dnaJ 10977953 dnaJ Zobellia galactanivorans Co-chaperone protein dnaJ YP_004737250.1 3287779 D 63186 CDS YP_004737251.1 340618798 10977753 3289081..3290019 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; Family membership; ABC transporter ATPase 3290019 10977753 zobellia_2825 Zobellia galactanivorans ABC transporter ATPase YP_004737251.1 3289081 D 63186 CDS YP_004737252.1 340618799 10975480 3290012..3291340 1 NC_015844.1 Putatif ABC-2 type (ATP-binding cassette) transporter, membrane domain possibly involved in the defense mechanisms by extrusion of a variety of compounds such as antibiotics, heavy metals or solvents across biological membranes; Contains seven transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 3291340 10975480 zobellia_2826 Zobellia galactanivorans ABC transporter permease YP_004737252.1 3290012 D 63186 CDS YP_004737253.1 340618800 10975481 3291325..3292236 1 NC_015844.1 Mechanosensitive channels (MS) provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation; Contains four transmembrane helices; Belongs to the small-conductance MS channels; Localized in the cytoplasmic membrane; Specificity unclear; small-conductance mechanosensitive channel 3292236 10975481 zobellia_2827 Zobellia galactanivorans small-conductance mechanosensitive channel YP_004737253.1 3291325 D 63186 CDS YP_004737254.1 340618801 10975482 3292355..3293134 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3293134 10975482 zobellia_2828 Zobellia galactanivorans hypothetical protein YP_004737254.1 3292355 D 63186 CDS YP_004737255.1 340618802 10975483 3293147..3294310 1 NC_015844.1 These response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes, activating the expression of genes from factor sigma-54 specific promoters. These proteins consist of two domains, an N- terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a C- terminal domain that interacts with the sigma 54 factor; Family membership; sigma-54 dependent two-component system-response regulator 3294310 10975483 zobellia_2829 Zobellia galactanivorans sigma-54 dependent two-component system-response regulator YP_004737255.1 3293147 D 63186 CDS YP_004737256.1 340618803 10975484 complement(3294320..3295021) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3295021 10975484 zobellia_2830 Zobellia galactanivorans lipoprotein YP_004737256.1 3294320 R 63186 CDS YP_004737257.1 340618804 10975486 3295223..3296107 1 NC_015844.1 Ppk2 was first identified in Pseudomonas aeruginosa by Zhang and cowokers (PNAS, 2006). Ppk2 belongs to a polyphosphate kinase family unrelated to that of Ppk1. Pkk2 also distinguished from PPK1 by the following: synthesis of poly P from GTP or ATP, a preference for Mn2+ over Mg2+, and a stimulation by poly P. The reverse reaction, a poly P-driven nucleoside diphosphate kinase synthesis of GTP from GDP, is 75-fold greater than the forward reaction, poly P synthesis from GTP. Localized in the cytoplasm.; High confidence in function and specificity; polyphosphate kinase 2 3296107 ppk2 10975486 ppk2 Zobellia galactanivorans polyphosphate kinase 2 YP_004737257.1 3295223 D 63186 CDS YP_004737258.1 340618805 10978374 3296104..3297498 1 NC_015844.1 Family M28 contains aminopeptidases and carboxypeptidases with two co-catalytic zinc ions (I and II). Each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. The zinc ligands occur in the sequence in the order His (II), Asp (I and II), Glu (I), Asp or Glu (II) and His (I). In addition, two other residues, an Asp and a Glu, are believed to be important for catalysis. Four of these residues occur in the motifs His-Xaa-Asp and Glu-Glu. Features a signal peptide cleaved between the residues 20 and 21. Localized in the periplasm.; Specificity unclear; metallopeptidase 3297498 10978374 zobellia_2832 Zobellia galactanivorans metallopeptidase YP_004737258.1 3296104 D 63186 CDS YP_004737259.1 340618806 10975487 3297648..3298580 1 NC_015844.1 Peptidyl-prolyl cis-trans isomerase, or PPIase or rotamase, accelerates the folding of proteins. It catalyzes the peptidyl-prolyl isomerisation during which the peptide bond preceding proline (the peptidyl-prolyl bond) is stabilised in the cis conformation in oligopeptides; Contains a N-terminal Cyclophilin type PPIase/CLD and a C-terminal FKBP-type peptidyl-prolyl cis- trans isomerase; Localized in the cytoplasm; High confidence in function and specificity; peptidyl-prolyl cis-trans isomerase 3298580 ppiB 10975487 ppiB Zobellia galactanivorans peptidyl-prolyl cis-trans isomerase YP_004737259.1 3297648 D 63186 CDS YP_004737260.1 340618807 10978372 complement(3299085..3299279) 1 NC_015844.1 Cold shock proteins (CSPs) help the cell to survive in temperatures lower than optimum growth temperature. CSPs may act as RNA chaperones by destabilizing RNA secondary structures, regulating ribosomal translation, rate of mRNA degradation and termination of transcription; Contains a 'cold-shock domain' (CSD) involved in the single-strand nucleic-acid binding; Localized in the cytoplasm; High confidence in function and specificity; Cold shock protein CspA 3299279 cspA3 10978372 cspA3 Zobellia galactanivorans Cold shock protein CspA YP_004737260.1 3299085 R 63186 CDS YP_004737261.1 340618808 10977687 complement(3299640..3300278) 1 NC_015844.1 Peroxiredoxins are thiol peroxidase. They are involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. The peroxidase reaction comprises two steps centered around a redox- active cysteine called the peroxidatic cysteine. It attacks the peroxide substrate and is oxidized to S-hydroxycysteine (a sulfenic acid). The second step is the regeneration of cysteine from S-hydroxycysteine. This regeneration is due to thiol-containing reductants such as thioredoxin. Localized in the cytoplasm.; Specificity unclear; peroxiredoxin 3300278 10977687 zobellia_2835 Zobellia galactanivorans peroxiredoxin YP_004737261.1 3299640 R 63186 CDS YP_004737262.1 340618809 10975488 3300349..3300936 1 NC_015844.1 YfiT exists as a dimer and binds Ni(2+) in a 1:1 stoichiometry. The protein has an unusual four-helix bundle topology and coordinates Ni(2+) in an octahedral geometry with three conserved histidines and three waters. Although there is no similarity in their overall structures, the coordination geometry of the metal and the residues that constitute the putative active site in YfiT are; Function unclear; Putative metal-dependent hydrolase YfiT 3300936 yfiT 10975488 yfiT Zobellia galactanivorans Putative metal-dependent hydrolase YfiT YP_004737262.1 3300349 D 63186 CDS YP_004737263.1 340618810 10978783 complement(3300947..3301504) 1 NC_015844.1 Peroxiredoxins are thiol peroxidase. They are involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. The peroxidase reaction comprises two steps centered around a redox- active cysteine called the peroxidatic cysteine. It attacks the peroxide substrate and is oxidized to S-hydroxycysteine (a sulfenic acid). The second step is the regeneration of cysteine from S-hydroxycysteine. This regeneration is due to thiol-containing reductants such as thioredoxin. Localized in the cytoplasm.; Family membership; peroxiredoxin 3301504 10978783 zobellia_2837 Zobellia galactanivorans peroxiredoxin YP_004737263.1 3300947 R 63186 CDS YP_004737264.1 340618811 10975489 3301617..3301955 1 NC_015844.1 CsaA could serves as a molecular chaperone for exported proteins or alternatively acts by stabilizing the secA protein. Belongs to a putative tRNA binding domain family. Localized in the cytoplasm.; Function unclear; protein CsaA 3301955 csaA 10975489 csaA Zobellia galactanivorans protein CsaA YP_004737264.1 3301617 D 63186 CDS YP_004737265.1 340618812 10977683 3301960..3302880 1 NC_015844.1 Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains nine transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sodium/solute symporter 3302880 10977683 zobellia_2839 Zobellia galactanivorans sodium/solute symporter YP_004737265.1 3301960 D 63186 CDS YP_004737266.1 340618813 10975490 3302877..3303920 1 NC_015844.1 Acyltransferase of unkown specificity. This family also incluses acyltransferases involved in phospholipid biosynthesis. Features a C-terminal transmembrane helix. Localized in the cytoplasmic membrane.; Specificity unclear; acyltransferase 3303920 10975490 zobellia_2840 Zobellia galactanivorans acyltransferase YP_004737266.1 3302877 D 63186 CDS YP_004737267.1 340618814 10975492 complement(3303996..3304376) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3304376 10975492 zobellia_2841 Zobellia galactanivorans hypothetical protein YP_004737267.1 3303996 R 63186 CDS YP_004737268.1 340618815 10975493 complement(3304449..3306203) 1 NC_015844.1 Possibly involved in the multidrug resistance by toxic compounds export; Contains six N-terminal transmembrane segments (ABC membrane) that form a pore in the cytoplasmic membrane an a C-terminal ATP-binding domain (ABC ATPase) responsible for energy generation; Belongs to the ABC-1 type transporter permease/ATP-binding family, MDR subfamily; High confidence in function and specificity; multidrug resistance-like, ATP-binding/permease protein 3306203 mdlA 10975493 mdlA Zobellia galactanivorans multidrug resistance-like, ATP-binding/permease protein YP_004737268.1 3304449 R 63186 CDS YP_004737269.1 340618816 10978130 3306558..3307472 1 NC_015844.1 NusB is a transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site. Localized in the cytoplasm.; High confidence in function and specificity; N utilization substance protein B 3307472 nusB 10978130 nusB Zobellia galactanivorans N utilization substance protein B YP_004737269.1 3306558 D 63186 CDS YP_004737270.1 340618817 10978282 3307513..3307983 1 NC_015844.1 Protein that contains a domain of unknown function DUF1573; Putative lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Family membership; membrane protein 3307983 10978282 zobellia_2844 Zobellia galactanivorans membrane protein YP_004737270.1 3307513 D 63186 CDS YP_004737271.1 340618818 10975494 3308008..3308295 1 NC_015844.1 Part of the secDF-yidC-yajC translocase complex. YajC is also present in a homo-oligomeric complex in excess of the other components. Contains one N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Function unclear; preprotein translocase subunit 3308295 yajC 10975494 yajC Zobellia galactanivorans preprotein translocase subunit YP_004737271.1 3308008 D 63186 CDS YP_004737272.1 340618819 10978772 3308408..3309757 1 NC_015844.1 NAD(P)-dependent dehydrogenase. Belongs to the Rossmann fold family. Features a twin-arginine translocation signal peptide.; Function unclear; NAD(P)-dependent dehydrogenase 3309757 10978772 zobellia_2846 Zobellia galactanivorans NAD(P)-dependent dehydrogenase YP_004737272.1 3308408 D 63186 CDS YP_004737273.1 340618820 10975495 complement(3310024..3310236) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3310236 10975495 zobellia_2847 Zobellia galactanivorans hypothetical protein YP_004737273.1 3310024 R 63186 CDS YP_004737274.1 340618821 10975496 complement(3310281..3311510) 1 NC_015844.1 Tripeptide aminopeptidase releases the N-terminal amino acid from tripeptides. Has a preference for tripeptides containing a N-terminal methionine or leucine. Belongs to the family 20 of the metallopeptidases. PepT binds two co-catalytic zinc ions, which are coordinated by five conserved residues (His/Asp, Asp, Glu, Glu/Asp, His). The zinc ions stabilize the tetrahedral intermediate and activate the catalytic water molecule. Localized in the cytoplasm.; High confidence in function and specificity; Tripeptide aminopeptidase, family M20 3311510 pepT 10975496 pepT Zobellia galactanivorans Tripeptide aminopeptidase, family M20 YP_004737274.1 3310281 R 63186 CDS YP_004737275.1 340618822 10978329 3311655..3314636 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-92) and the Plug module (109-232) acting as a channel gate; The signal peptide is cleaved between the residues 21 and 22; Family membership; TonB-dependent Receptor 3314636 10978329 zobellia_2849 Zobellia galactanivorans TonB-dependent Receptor YP_004737275.1 3311655 D 63186 CDS YP_004737276.1 340618823 10975497 3314757..3315221 1 NC_015844.1 Contains a signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3315221 10975497 zobellia_2850 Zobellia galactanivorans periplasmic protein YP_004737276.1 3314757 D 63186 CDS YP_004737277.1 340618824 10975499 3315348..3316391 1 NC_015844.1 Dihydroorotate dehydrogenase catalyzes the fourth step in the de novo biosynthesis of pyrimidine, the conversion of dihydroorotate into orotate. It forms a homodimer and binds one FMN as cofactor pare subunit. Localized in the cytoplasm.; High confidence in function and specificity; dihydroorotate dehydrogenase 3316391 pyrD 10975499 pyrD Zobellia galactanivorans dihydroorotate dehydrogenase YP_004737277.1 3315348 D 63186 CDS YP_004737278.1 340618825 10978419 complement(3316423..3316842) 1 NC_015844.1 Contains a dimeric alpha-beta barrel domain possibly involved in the stress response; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3316842 10978419 zobellia_2852 Zobellia galactanivorans periplasmic protein YP_004737278.1 3316423 R 63186 CDS YP_004737279.1 340618826 10975500 3317069..3317695 1 NC_015844.1 RthB conducts the efflux of homoserine and homoserine lactone. Features six transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; homoserine/homoserine lactone efflux protein 3317695 rhtB 10975500 rhtB Zobellia galactanivorans homoserine/homoserine lactone efflux protein YP_004737279.1 3317069 D 63186 CDS YP_004737280.1 340618827 10978458 3317754..3318620 1 NC_015844.1 Hydroxymethylglutaryl-CoA lyase is involved in mevalonate catabolism. It cleaves the (S)-3-hydroxy-3-methylglutaryl-CoA to acetyl-CoA and acetoacetate; Localized in the cytoplasm; High confidence in function and specificity; hydroxymethylglutaryl-CoA lyase 3318620 mvaB 10978458 mvaB Zobellia galactanivorans hydroxymethylglutaryl-CoA lyase YP_004737280.1 3317754 D 63186 CDS YP_004737281.1 340618828 10978217 complement(3318617..3318982) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3318982 10978217 zobellia_2855 Zobellia galactanivorans hypothetical protein YP_004737281.1 3318617 R 63186 CDS YP_004737282.1 340618829 10975501 3319299..3320522 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3320522 10975501 zobellia_2856 Zobellia galactanivorans lipoprotein YP_004737282.1 3319299 D 63186 CDS YP_004737283.1 340618830 10975502 3320634..3321764 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3321764 10975502 zobellia_2857 Zobellia galactanivorans lipoprotein YP_004737283.1 3320634 D 63186 CDS YP_004737284.1 340618831 10975503 3321768..3323135 1 NC_015844.1 Vitamin K-dependent gamma-glutamyl carboxylase catalyzes the Vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues to gamma-carboxyglutamate in various proteins; Contains eight transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; vitamin K-dependent gamma-glutamyl carboxylase 3323135 ggcX 10975503 ggcX Zobellia galactanivorans vitamin K-dependent gamma-glutamyl carboxylase YP_004737284.1 3321768 D 63186 CDS YP_004737285.1 340618832 10977894 3323116..3325590 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (23-99) and the Plug module (130-240) acting as a channel gate; The signal peptide is cleaved between the residues 21 and 22; Family membership; TonB-dependent Receptor 3325590 10977894 zobellia_2859 Zobellia galactanivorans TonB-dependent Receptor YP_004737285.1 3323116 D 63186 CDS YP_004737286.1 340618833 10975504 3325596..3325718 1 NC_015844.1 Hypothetical protein; hypothetical protein 3325718 10975504 zobellia_2860 Zobellia galactanivorans hypothetical protein YP_004737286.1 3325596 D 63186 CDS YP_004737287.1 340618834 10975506 3325802..3327274 1 NC_015844.1 Inosine-5'-monophosphate dehydrogenase catalyzes the rate-limiting reaction of de novo GTP biosynthesis, the NAD-dependent reduction of IMP into XMP. It also features two N-termianl CBS (cystathionine-beta-synthase) domains. Tandem pairs of CBS domains can act as binding domains for adenosine derivatives and may regulate the activity of attached enzymatic domains. GuaB forms a homotetramer and is localized in the cytoplasm.; High confidence in function and specificity; inosine-5'-monophosphate dehydrogenase 3327274 guaB 10975506 guaB Zobellia galactanivorans inosine-5'-monophosphate dehydrogenase YP_004737287.1 3325802 D 63186 CDS YP_004737288.1 340618835 10977955 complement(3327307..3329874) 1 NC_015844.1 Aminopeptidase catalyzes the hydrolysis of N-terminal amino-acid residues from oligopeptides or polypeptides. This enzyme belongs to the family M1 of the peptidases. A catalytic zinc ion is bound by two histidines and a glutamate. The histidines are within an 'HEXXH' motif on one long helix with the glutamate on another antiparallel helix. The catalytic mechanism is believed to involve activation of a water molecule by the zinc ion. The glutamate of the HEXXH motif is known to be important for catalysis and a tyrosine may also be involved. Localized in the cytoplasm; Specificity unclear; aminopeptidase 3329874 10977955 zobellia_2862 Zobellia galactanivorans aminopeptidase YP_004737288.1 3327307 R 63186 CDS YP_004737289.1 340618836 10975507 complement(3330030..3330554) 1 NC_015844.1 Conserved protein belonging to the thioredoxin family. Thioredoxins are small proteins of approximately one hundred amino-acid residues which participate in various redox reactions via the reversible oxidation of an active center disulfide bond. Features a signal peptide cleaved between the residues 23 and 24. Localized in the periplasm.; Family membership; thioredoxin family protein 3330554 10975507 zobellia_2863 Zobellia galactanivorans thioredoxin family protein YP_004737289.1 3330030 R 63186 CDS YP_004737290.1 340618837 10975508 complement(3330615..3331856) 1 NC_015844.1 Diaminopimelate decarboxylase catalyzes the conversion of diaminopimelic acid into lysine, the final step of lysine biosynthesis. Binds pyridoxal phosphate as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; diaminopimelate decarboxylase 3331856 lysA 10975508 lysA Zobellia galactanivorans diaminopimelate decarboxylase YP_004737290.1 3330615 R 63186 CDS YP_004737291.1 340618838 10978111 3332023..3332661 1 NC_015844.1 Protein displaying weak similarity with the N-terminal non-peptidase domain of the ATP-dependent peptidase LonA; Localized in the cytoplasm; Conserved hypothetical protein; hypothetical protein 3332661 10978111 zobellia_2865 Zobellia galactanivorans hypothetical protein YP_004737291.1 3332023 D 63186 CDS YP_004737292.1 340618839 10975509 3332841..3334034 1 NC_015844.1 Succinyl-CoA ligase functions in the citric acid cycle, coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents an important site of substrate-level phosphorylation. It can also function in the other direction for anabolic purposes. It forms a heterotetramer of two alpha and two beta subunits. The alpha subunit binds CoA, as well as ATP and catalyzes phosphoryl transfer to one of its histidine residues. The complete active site is probably located in the region of alpha-beta contact. Localized in the cytoplasm.; High confidence in function and specificity; succinyl-CoA ligase [ADP-forming] subunit beta 3334034 sucC 10975509 sucC Zobellia galactanivorans succinyl-CoA ligase [ADP-forming] subunit beta YP_004737292.1 3332841 D 63186 CDS YP_004737293.1 340618840 10978616 3334315..3334659 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3334659 10978616 zobellia_2867 Zobellia galactanivorans periplasmic protein YP_004737293.1 3334315 D 63186 CDS YP_004737294.1 340618841 10975510 complement(3334729..3335814) 1 NC_015844.1 Alanine dehydrogenase is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid. It catalyzes the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. It forms a homohexamer and binds one NAD+ per subunit as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; alanine dehydrogenase 3335814 ald1 10975510 ald1 Zobellia galactanivorans alanine dehydrogenase YP_004737294.1 3334729 R 63186 CDS YP_004737295.1 340618842 10977489 complement(3335937..3337088) 1 NC_015844.1 Possible permease that consists to eleven transmembrane segments; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3337088 10977489 zobellia_2869 Zobellia galactanivorans hypothetical protein YP_004737295.1 3335937 R 63186 CDS YP_004737296.1 340618843 10975511 complement(3337201..3338388) 1 NC_015844.1 The histidinol-phosphate aminotransferase catalyses the transfer of an amino group from 3-(imidazol-4-yl)-2-oxopropyl phosphate to glutamic acid to form histidinol phosphate and 2-oxoglutarate using the Pyridoxal phosphate as cofactor bound by covalent linkage to a lysine residue; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily; Possibly exported in the periplasmic space by a twin-arginine signal peptide (cleavage site between 32 and 33); High confidence in function and specificity; histidinol-phosphate aminotransferase 3338388 hisC2 10975511 hisC2 Zobellia galactanivorans histidinol-phosphate aminotransferase YP_004737296.1 3337201 R 63186 CDS YP_004737297.1 340618844 10977978 complement(3338422..3339042) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21, Localized in the outer membrane; Hypothetical protein; hypothetical protein 3339042 10977978 zobellia_2871 Zobellia galactanivorans hypothetical protein YP_004737297.1 3338422 R 63186 CDS YP_004737298.1 340618845 10975513 complement(3339080..3342028) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (23-96) and the Plug module (114-236) acting as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 3342028 10975513 zobellia_2872 Zobellia galactanivorans TonB-dependent Receptor YP_004737298.1 3339080 R 63186 CDS YP_004737299.1 340618846 10975514 3342589..3343050 1 NC_015844.1 The transcriptional regulator AsnC is the activator of the asnA gene involved in the asparagine synthesis and is a autogenous regulator of its own transcription; Contains a N-terminal AsnC/Lrp-type HTH domain; Localized in the cytoplasm; High confidence in function and specificity; transcriptional regulator AsnC 3343050 asnC1 10975514 asnC1 Zobellia galactanivorans transcriptional regulator AsnC YP_004737299.1 3342589 D 63186 CDS YP_004737300.1 340618847 10977559 3343242..3343544 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3343544 10977559 zobellia_2874 Zobellia galactanivorans hypothetical protein YP_004737300.1 3343242 D 63186 CDS YP_004737301.1 340618848 10975515 complement(3343596..3343958) 1 NC_015844.1 Protein belonging to the DUF1456 family; Localized in the cytoplasm; hypothetical protein 3343958 10975515 zobellia_2875 Zobellia galactanivorans hypothetical protein YP_004737301.1 3343596 R 63186 CDS YP_004737302.1 340618849 10975516 3344204..3344629 1 NC_015844.1 Heat shock protein belonging to the HSP20 family. Acts as chaperone that can protect other proteins against heat-induced denaturation and aggregation. Hsp20 proteins seem to form large heterooligomeric aggregates. Localized in the cytoplasm.; Family membership; small heat shock protein 3344629 10975516 zobellia_2876 Zobellia galactanivorans small heat shock protein YP_004737302.1 3344204 D 63186 CDS YP_004737303.1 340618850 10975517 3344804..3344908 1 NC_015844.1 Hypothetical protein; hypothetical protein 3344908 10975517 zobellia_2877 Zobellia galactanivorans hypothetical protein YP_004737303.1 3344804 D 63186 CDS YP_004737304.1 340618851 10975518 complement(3345022..3347010) 1 NC_015844.1 The UvrB protein belongs to the UvrABC repair system responsible of the recognition and processing of DNA lesions; This system is a complex composed of 2 UvrA (ATPase) and 2 UvrB subunits. UvrB is a helicase that probes one DNA strand for the presence of a lesion. If a lesion is found, the UvrA subunits dissociate and the UvrB-DNA preincision complex is subsequently bound by UvrC (endonuclease). If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage; Contains a C-terminal UVR domain that can interact with the homologous domain in UvrC; Localized in the cytoplasm; High confidence in function and specificity; excinuclease ABC subunit B 3347010 uvrB 10975518 uvrB Zobellia galactanivorans excinuclease ABC subunit B YP_004737304.1 3345022 R 63186 CDS YP_004737305.1 340618852 10978733 3347364..3347756 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3347756 10978733 zobellia_2879 Zobellia galactanivorans hypothetical protein YP_004737305.1 3347364 D 63186 CDS YP_004737306.1 340618853 10975519 complement(3348032..3348865) 1 NC_015844.1 ABC (ATP-binding cassette) transporter, membrane domain; Proteins responsible for import of a variety of compounds across biological membranes; Contains six transmembrane segmemts; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 3348865 10975519 zobellia_2880 Zobellia galactanivorans ABC transporter permease YP_004737306.1 3348032 R 63186 CDS YP_004737307.1 340618854 10975521 complement(3348871..3349773) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; Family membership; ABC transporter ATPase 3349773 10975521 zobellia_2881 Zobellia galactanivorans ABC transporter ATPase YP_004737307.1 3348871 R 63186 CDS YP_004737308.1 340618855 10975522 complement(3349842..3351854) 1 NC_015844.1 Contains a domain of unknown function (DUF 11) and a fragment of 34 residues of Actin-binding like protein (Filamin/ABP280); Signal peptide cleaved betwenn the residues 20 and 21; Putatively localized in the outer membrane; hypothetical protein 3351854 10975522 zobellia_2882 Zobellia galactanivorans hypothetical protein YP_004737308.1 3349842 R 63186 CDS YP_004737309.1 340618861 10975523 complement(3352042..3364344) 1 NC_015844.1 Contains a B_ant_repeat domain (DUF 11) in the N-terminal region; Shows 56% of identity with the N-terminal domain of ORF 609; Signal peptide cleaved between the residues 26 and 27; Putatively localized in the outer membrane (PSORT result); hypothetical protein 3364344 10975523 zobellia_2888 Zobellia galactanivorans hypothetical protein YP_004737309.1 3352042 R 63186 CDS YP_004737310.1 340618856 10975529 3360691..3360927 1 NC_015844.1 Hypothetical protein; hypothetical protein 3360927 10975529 zobellia_2883 Zobellia galactanivorans hypothetical protein YP_004737310.1 3360691 D 63186 CDS YP_004737311.1 340618857 10975524 3360953..3361237 1 NC_015844.1 Hypothetical protein; hypothetical protein 3361237 10975524 zobellia_2884 Zobellia galactanivorans hypothetical protein YP_004737311.1 3360953 D 63186 CDS YP_004737312.1 340618858 10975525 3362402..3362713 1 NC_015844.1 Hypothetical protein; hypothetical protein 3362713 10975525 zobellia_2885 Zobellia galactanivorans hypothetical protein YP_004737312.1 3362402 D 63186 CDS YP_004737313.1 340618859 10975526 3363035..3363280 1 NC_015844.1 Hypothetical protein; hypothetical protein 3363280 10975526 zobellia_2886 Zobellia galactanivorans hypothetical protein YP_004737313.1 3363035 D 63186 CDS YP_004737314.1 340618860 10975527 3363445..3363687 1 NC_015844.1 Hypothetical protein; hypothetical protein 3363687 10975527 zobellia_2887 Zobellia galactanivorans hypothetical protein YP_004737314.1 3363445 D 63186 CDS YP_004737315.1 340618862 10975528 3364512..3365594 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3365594 10975528 zobellia_2889 Zobellia galactanivorans hypothetical protein YP_004737315.1 3364512 D 63186 CDS YP_004737316.1 340618863 10975530 complement(3365653..3366711) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3366711 10975530 zobellia_2890 Zobellia galactanivorans hypothetical protein YP_004737316.1 3365653 R 63186 CDS YP_004737317.1 340618864 10975532 complement(3366809..3367303) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3367303 10975532 zobellia_2891 Zobellia galactanivorans hypothetical protein YP_004737317.1 3366809 R 63186 CDS YP_004737318.1 340618865 10975533 complement(3367331..3368365) 1 NC_015844.1 CtaA is required for cytochrome aa3 biosynthesis. Features eight transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; cytochrome aa3-controlling protein 3368365 ctaA 10975533 ctaA Zobellia galactanivorans cytochrome aa3-controlling protein YP_004737318.1 3367331 R 63186 CDS YP_004737319.1 340618866 10977691 complement(3368446..3370374) 1 NC_015844.1 This protein has a modular architecture consisting of a N-terminal TPR motif, a central beta-propeller domain, encompassing three WD40 repeats, and a C-terminal OmpA domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan. The tetratrico peptide repeat (TPR) is a structural motif, which mediates proteinprotein interactions; Signal peptide cleaved between the residues 23 and 24; localized in the periplasmic space and/or outer membrane; Family membership; OmpA-like periplasmic protein 3370374 10977691 zobellia_2893 Zobellia galactanivorans OmpA-like periplasmic protein YP_004737319.1 3368446 R 63186 CDS YP_004737320.1 340618867 10975534 complement(3370376..3371314) 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3371314 10975534 zobellia_2894 Zobellia galactanivorans membrane protein YP_004737320.1 3370376 R 63186 CDS YP_004737321.1 340618868 10975535 complement(3371330..3380098) 1 NC_015844.1 Contains several Single hybrid motifs found in biotinyl/lipoyl-carrier proteins and domains, where the biotin and lipoic acid moieties act as covalently attached coenzyme in various enzymes; Signal peptide cleaved between the residues 23 and 24; Putatively localized in the cytoplasmic membrane; hypothetical protein 3380098 10975535 zobellia_2895 Zobellia galactanivorans hypothetical protein YP_004737321.1 3371330 R 63186 CDS YP_004737322.1 340618869 10975536 complement(3380381..3381322) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3381322 10975536 zobellia_2896 Zobellia galactanivorans periplasmic protein YP_004737322.1 3380381 R 63186 CDS YP_004737323.1 340618870 10975537 3381429..3381539 1 NC_015844.1 Hypothetical protein; hypothetical protein 3381539 10975537 zobellia_2897 Zobellia galactanivorans hypothetical protein YP_004737323.1 3381429 D 63186 CDS YP_004737324.1 340618871 10975538 complement(3381536..3382960) 1 NC_015844.1 CcA catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows highest phosphatase activity in the presence of Ni(2+) and hydrolyzes pyrophosphate, canonical 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi. Displays a metal-independent phosphodiesterase activity toward 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP. Without metal or in the presence of Mg(2+), this protein hydrolyzes 2',3'-cyclic substrates with the formation of 2'-nucleotides, whereas in the presence of Ni(2+), it also produces some 3'-nucleotides. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. Localized in the cytoplasm.; High confidence in function and specificity; multifunctional CCA protein 3382960 cca 10975538 cca Zobellia galactanivorans multifunctional CCA protein YP_004737324.1 3381536 R 63186 CDS YP_004737325.1 340618872 10977626 complement(3383022..3383582) 1 NC_015844.1 Conserved protein belonging to the YrdC family . The YrdC protein from E. coli forms an alpha/beta twisted open-sheet structure composed of seven alpha helices and seven beta strands. YrdC was shown to binds double-stranded RNA. Its exact function is unclear. Localized in the cytoplasm.; Function unclear; YrdC family protein 3383582 10977626 zobellia_2899 Zobellia galactanivorans YrdC family protein YP_004737325.1 3383022 R 63186 CDS YP_004737326.1 340618873 10975539 complement(3383554..3384417) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3384417 10975539 zobellia_2900 Zobellia galactanivorans hypothetical protein YP_004737326.1 3383554 R 63186 CDS YP_004737327.1 340618874 10975541 complement(3384440..3385315) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3385315 10975541 zobellia_2901 Zobellia galactanivorans hypothetical protein YP_004737327.1 3384440 R 63186 CDS YP_004737328.1 340618875 10975542 3385375..3386208 1 NC_015844.1 Putatively involved in the exopolysaccharide biosynthesis; Belongs to the family 2 of glycosyl transferase (GT2); Localized in the cytoplasm; Family membership; glycosyltransferase 3386208 10975542 zobellia_2902 Zobellia galactanivorans glycosyltransferase YP_004737328.1 3385375 D 63186 CDS YP_004737329.1 340618876 10975543 complement(3386190..3386984) 1 NC_015844.1 Putatively involved in the Lipopolysaccharide core biosynthesis; Belongs to the family 2 of glycosyl transferase (GT2), WaaE/kdtX subfamily; Localized in the cytoplasm; Function unclear; lipopolysaccharide core biosynthesis glycosyltransferase 3386984 waaE 10975543 waaE Zobellia galactanivorans lipopolysaccharide core biosynthesis glycosyltransferase YP_004737329.1 3386190 R 63186 CDS YP_004737330.1 340618877 10978747 complement(3387138..3387953) 1 NC_015844.1 DapD is involved in L-Lysine and diaminopimelate biosynthesis. It catalyzes the reaction: Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate. Localized in the cytoplasm.; High confidence in function and specificity; 2,3,4,5-Tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 3387953 dapD 10978747 dapD Zobellia galactanivorans 2,3,4,5-Tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase YP_004737330.1 3387138 R 63186 CDS YP_004737331.1 340618878 10977717 3388088..3388567 1 NC_015844.1 Holliday junction resolvases (HJRs) are key enzymes of DNA recombination; Could be a nuclease that resolves Holliday junction intermediates in genetic recombination; Display a RNase H fold; Localized in the cytoplasm; Specificity unclear; Holliday junction resolvase 3388567 yqgF 10977717 yqgF Zobellia galactanivorans Holliday junction resolvase YP_004737331.1 3388088 D 63186 CDS YP_004737332.1 340618879 10978791 3388568..3389158 1 NC_015844.1 Formylmethionine deformylase or peptide deformylase (PDF) is an essential metalloenzyme required for the removal of the formyl group at the N-terminal Met of nascent polypeptide chains in eubacteria. The enzyme acts as a monomer and binds a single zinc ion. Catalytic efficiency strongly depends on the identity of the bound metal; Localized in the cytoplasm; High confidence in function and specificity; formylmethionine deformylase 3389158 defA 10978791 defA Zobellia galactanivorans formylmethionine deformylase YP_004737332.1 3388568 D 63186 CDS YP_004737333.1 340618880 10977728 3389219..3389638 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 3389638 10977728 zobellia_2907 Zobellia galactanivorans hypothetical protein YP_004737333.1 3389219 D 63186 CDS YP_004737334.1 340618881 10975544 3389868..3390311 1 NC_015844.1 Protein, involved in sensory transduction in microorganisms, and that consists of an N-terminal BLUF (sensors of blue-light using FAD) domain. This domain is involved in sensing blue-light (and possibly redox) using FAD and is Localized in the cytoplasm; Function unclear; expression activator-like protein 3390311 10975544 zobellia_2908 Zobellia galactanivorans expression activator-like protein YP_004737334.1 3389868 D 63186 CDS YP_004737335.1 340618882 10975545 3390765..3391853 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains an N- terminal PAS/PAC domain involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 3391853 10975545 zobellia_2909 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004737335.1 3390765 D 63186 CDS YP_004737336.1 340618883 10975546 3391869..3392261 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity that acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership; two-component system-response regulator, receiver domain 3392261 10975546 zobellia_2910 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004737336.1 3391869 D 63186 CDS YP_004737337.1 340618884 10975548 complement(3392324..3393940) 1 NC_015844.1 Beta-N-acetylhexosaminidase catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; Belongs to the family 20 of the glycoside hydrolases (GH20); Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; High confidence in function and specificity; beta-N-acetylhexosaminidase 3393940 nahA2 10975548 nahA2 Zobellia galactanivorans beta-N-acetylhexosaminidase YP_004737337.1 3392324 R 63186 CDS YP_004737338.1 340618885 10978229 complement(3393976..3394614) 1 NC_015844.1 Converts an acetic ester to an alcohol and acetate; Belongs to the SGNH-hydrolase superfamily, lipase-GDSL family, which includes families 3 and 12 of the carbohydrate esterases (CE3 and CE12); Signal peptide cleaved between the residues 17 and 18; Localized in the periplasmic space; Specificity unclear; lipase-GDSL family acetylesterase 3394614 10978229 zobellia_2912 Zobellia galactanivorans lipase-GDSL family acetylesterase YP_004737338.1 3393976 R 63186 CDS YP_004737339.1 340618886 10975549 complement(3394621..3395496) 1 NC_015844.1 Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides; Belongs to the family 10 of the carbohydrate esterases (CE10); Signal peptide cleaved between residues 19 and 20; Localized in the periplasmic space; Specificity unclear; carbohydrate esterase 3395496 10975549 zobellia_2913 Zobellia galactanivorans carbohydrate esterase YP_004737339.1 3394621 R 63186 CDS YP_004737340.1 340618887 10975550 complement(3395535..3396260) 1 NC_015844.1 Glycerol enters the cell via the glycerol diffusion facilitator protein. This membrane protein facilitates the movement of glycerol across the cytoplasmic membrane. Belongs to the Major Intrinsinc Protein family which also includes aquaporin. Features six transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; glycerol uptake facilitator protein 3396260 glpF 10975550 glpF Zobellia galactanivorans glycerol uptake facilitator protein YP_004737340.1 3395535 R 63186 CDS YP_004737341.1 340618888 10977925 complement(3396396..3396848) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3396848 10977925 zobellia_2915 Zobellia galactanivorans hypothetical protein YP_004737341.1 3396396 R 63186 CDS YP_004737342.1 340618889 10975551 3397047..3397472 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Hypothetical protein; hypothetical protein 3397472 10975551 zobellia_2916 Zobellia galactanivorans hypothetical protein YP_004737342.1 3397047 D 63186 CDS YP_004737343.1 340618890 10975552 3397619..3398701 1 NC_015844.1 These membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics, solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmic membrane by a N-terminal transmembrane region; Belongs to the type I secretion system; Family membership; membrane fusion protein 3398701 10975552 zobellia_2917 Zobellia galactanivorans membrane fusion protein YP_004737343.1 3397619 D 63186 CDS YP_004737344.1 340618891 10975553 3398727..3401933 1 NC_015844.1 Integral membrane protein involved in drug resistance that belongs to the acrB/acrD/acrF family; Contains 12 transmembrane segments and two large periplasmic domains (each exceeding 300 residues) between helices 1 and 2, and helices 9 and 10. The three transmembrane domains form a large, 30-wide central cavity that spans the cytoplasmic membrane and extends to the cytoplasm; Localized in the cytoplasmic membrane; Family membership; multidrug efflux transporter 3401933 10975553 zobellia_2918 Zobellia galactanivorans multidrug efflux transporter YP_004737344.1 3398727 D 63186 CDS YP_004737345.1 340618892 10975554 3401956..3403389 1 NC_015844.1 The outer membrane efflux proteins (OEP) are composed of two repeats of OEP domain to form a trimeric channel continuous, solvent-accessible conduit that spans both the outer membrane and periplasmic space; May be specialized for the signal peptide independent extracellular secretion of a variety of substrates in Gram-negative bacteria (type I secretion system); Lipoprotein-type signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Family membership; outer membrane efflux protein 3403389 10975554 zobellia_2919 Zobellia galactanivorans outer membrane efflux protein YP_004737345.1 3401956 D 63186 CDS YP_004737346.1 340618893 10975555 complement(3403478..3404389) 1 NC_015844.1 Gluconolactonases hydrolyze the gluconolactone, formed either by the glucose oxidoreductase or by the glucose dehydrogenase in aerobic conditions, to gluconate; Contains a putative lipoprotein signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; High confidence in function and specificity; gluconolactonase 3404389 gnlA 10975555 gnlA Zobellia galactanivorans gluconolactonase YP_004737346.1 3403478 R 63186 CDS YP_004737347.1 340618894 10977940 complement(3404392..3405231) 1 NC_015844.1 Protein belonging to the Xylose isomerase-like TIM barrel family; Contains a twin-arginine translocation pathway signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; Family membership; xylose isomerase-like TIM barrel protein 3405231 10977940 zobellia_2921 Zobellia galactanivorans xylose isomerase-like TIM barrel protein YP_004737347.1 3404392 R 63186 CDS YP_004737348.1 340618895 10975557 3405331..3406113 1 NC_015844.1 MazG is a nucleoside triphosphate pyrophosphohydrolase which can hydrolyze all eight of the canonical ribo- and deoxynucleoside triphosphates to their respective monophosphates and PP(i), with a preference for deoxynucleotides. MazG also interacts with Era, an essential GTPase; Localized in the cytoplasm; High confidence in function and specificity; nucleoside triphosphate pyrophosphohydrolase MazG 3406113 mazG 10975557 mazG Zobellia galactanivorans nucleoside triphosphate pyrophosphohydrolase MazG YP_004737348.1 3405331 D 63186 CDS YP_004737349.1 340618896 10978126 3406195..3407565 1 NC_015844.1 Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Contains 12 transmembrane segments; Belongs to the multi antimicrobial extrusion (MATE) family, MdtK subfamily; Localized in the cytoplasmic membrane; Specificity unclear; multidrug resistance protein 3407565 norM1 10978126 norM1 Zobellia galactanivorans multidrug resistance protein YP_004737349.1 3406195 D 63186 CDS YP_004737350.1 340618897 10978257 3407567..3407794 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3407794 10978257 zobellia_2924 Zobellia galactanivorans hypothetical protein YP_004737350.1 3407567 D 63186 CDS YP_004737351.1 340618898 10975558 3407800..3408381 1 NC_015844.1 Undecaprenyl-diphosphatase catalyzes the hydrolysis of dolichol pyrophosphate, likely in connection with glycosylation reactions of membrane; Contains five transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; UDP-diphosphatase 3408381 sepP2 10975558 sepP2 Zobellia galactanivorans UDP-diphosphatase YP_004737351.1 3407800 D 63186 CDS YP_004737352.1 340618899 10978580 3408365..3410020 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; Belongs to the family 83 of the glycosyltransferases (GT83); Contains eleven transmembrane segments; Localized in the cytoplasmic membrane; Specificity unclear; glycosyltransferase 3410020 10978580 zobellia_2926 Zobellia galactanivorans glycosyltransferase YP_004737352.1 3408365 D 63186 CDS YP_004737353.1 340618900 10975559 complement(3410035..3410997) 1 NC_015844.1 ArnC catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the family 2 of the glycosyltransferase (GT2); Contains three C-terminal transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; UDP-phosphate 4-deoxy-4-formamido-L-arabinose transferase 3410997 arnC2 10975559 arnC2 Zobellia galactanivorans UDP-phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_004737353.1 3410035 R 63186 CDS YP_004737354.1 340618901 10977542 complement(3411035..3412078) 1 NC_015844.1 The ArgK protein acts as an ATPase enzyme and as a kinase, and phosphorylates periplasmic binding proteins involved in the LAO (lysine, arginine, ornithine)/AO transport systems. This phosphorylation results in reduced levels of transport activity of the periplasmic transport systems that include each of the binding proteins; Localized in the cytoplasmic membrane; High confidence in function and specificity; LAO/AO transport system kinase ArgK 3412078 argK 10977542 argK Zobellia galactanivorans LAO/AO transport system kinase ArgK YP_004737354.1 3411035 R 63186 CDS YP_004737355.1 340618902 10977539 complement(3412080..3412658) 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3412658 10977539 zobellia_2929 Zobellia galactanivorans membrane protein YP_004737355.1 3412080 R 63186 CDS YP_004737356.1 340618903 10975560 3412793..3413218 1 NC_015844.1 OhrB is involved in organic hydroperoxide resistance. It is induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation. Expression is sigma B-dependent. Localized in the cytoplasm.; High confidence in function and specificity; organic hydroperoxide resistance protein ohrB 3413218 ohrB 10975560 ohrB Zobellia galactanivorans organic hydroperoxide resistance protein ohrB YP_004737356.1 3412793 D 63186 CDS YP_004737357.1 340618904 10978287 complement(3413273..3414178) 1 NC_015844.1 Aldose 1-epimerase or Mutarotase is responsible for the anomeric interconversion of aldoses between their alpha- and beta-forms; It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; Localized in the cytoplasm; High confidence in function and specificity; aldose 1-epimerase 3414178 mroA2 10978287 mroA2 Zobellia galactanivorans aldose 1-epimerase YP_004737357.1 3413273 R 63186 CDS YP_004737358.1 340618905 10978184 complement(3414378..3415064) 1 NC_015844.1 Peptide methionine sulphoxide reductase MsrA reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide to methionine. MsrA is specific for methionine-S-sulfoxides; Thioredoxin acts as a cofactor; Contains a prokaryotic lipoprotein signal peptide cleaved between 18 and 19; Localized in the outer membrane; High confidence in function and specificity; peptide methionine sulfoxide reductase 3415064 msrA3 10978184 msrA3 Zobellia galactanivorans peptide methionine sulfoxide reductase YP_004737358.1 3414378 R 63186 CDS YP_004737359.1 340618906 10978194 3415064..3415168 1 NC_015844.1 Hypothetical protein; hypothetical protein 3415168 10978194 zobellia_2933 Zobellia galactanivorans hypothetical protein YP_004737359.1 3415064 D 63186 CDS YP_004737360.1 340618907 10975561 complement(3415185..3416192) 1 NC_015844.1 Protein containing a bacterial Ig-like domain 1 (Big-1). Big-1 domains (~95 amino acids) are usually present in bacterial adhesion molecules of the intimin/invasin family, involved in pathogenicity. Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3416192 10975561 zobellia_2934 Zobellia galactanivorans lipoprotein YP_004737360.1 3415185 R 63186 CDS YP_004737361.1 340618908 10975562 3416497..3416682 1 NC_015844.1 Hypothetical protein; hypothetical protein 3416682 10975562 zobellia_2935 Zobellia galactanivorans hypothetical protein YP_004737361.1 3416497 D 63186 CDS YP_004737362.1 340618909 10975563 3416754..3416993 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3416993 10975563 zobellia_2936 Zobellia galactanivorans periplasmic protein YP_004737362.1 3416754 D 63186 CDS YP_004737363.1 340618910 10975564 complement(3417454..3417726) 1 NC_015844.1 Contains a central transmembrane segment; Putatively localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3417726 10975564 zobellia_2937 Zobellia galactanivorans hypothetical protein YP_004737363.1 3417454 R 63186 CDS YP_004737364.1 340618911 10975565 complement(3417948..3419162) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains six N-terminal transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; two-component system-sensor histidine kinase 3419162 10975565 zobellia_2938 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004737364.1 3417948 R 63186 CDS YP_004737365.1 340618912 10975566 complement(3419302..3420696) 1 NC_015844.1 Conserved NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Its exact specificity is unknown; Contains a Twin-arginine translocation pathway signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Specificity unclear; NAD(P)-dependent oxidoreductase 3420696 10975566 zobellia_2939 Zobellia galactanivorans NAD(P)-dependent oxidoreductase YP_004737365.1 3419302 R 63186 CDS YP_004737366.1 340618913 10975567 complement(3420766..3421983) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains six N-terminal transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; two-component system-sensor histidine kinase 3421983 10975567 zobellia_2940 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004737366.1 3420766 R 63186 CDS YP_004737367.1 340618914 10975569 complement(3422220..3423428) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains six N-terminal transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; two-component system-sensor histidine kinase 3423428 10975569 zobellia_2941 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004737367.1 3422220 R 63186 CDS YP_004737368.1 340618915 10975570 complement(3423731..3427093) 1 NC_015844.1 SecA is the ATPase subunit of the translocase, the preprotein translocation apparatus. SecA has a central role in coupling of the hydrolysis of ATP with the transfer of periplasmic and outer membrane proteins across the cytoplasmic membrane. SecA interacts with the integral membrane subunits secY/secE of the translocase; Localized in the cytoplasm; High confidence in function and specificity; preprotein translocase subunit secA 3427093 secA 10975570 secA Zobellia galactanivorans preprotein translocase subunit secA YP_004737368.1 3423731 R 63186 CDS YP_004737369.1 340618916 10978575 3427122..3427283 1 NC_015844.1 Hypothetical protein; hypothetical protein 3427283 10978575 zobellia_2943 Zobellia galactanivorans hypothetical protein YP_004737369.1 3427122 D 63186 CDS YP_004737370.1 340618917 10975571 complement(3427289..3427513) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3427513 10975571 zobellia_2944 Zobellia galactanivorans hypothetical protein YP_004737370.1 3427289 R 63186 CDS YP_004737371.1 340618918 10975572 complement(3427688..3428269) 1 NC_015844.1 ATP:cob(I)alamin (or ATP:corrinoid) adenosyltransferases catalyse the conversion of cobalamin (vitamin B12) into its coenzyme form, adenosylcobalamin (coenzyme B12), or via de novo synthesis. Adenosylcobalamin is required for the ativity of certain enzymes; The metabolic pathway where this enzyme is used is unknown; Belongs to the Cob(I)alamin adenosyltransferase family; Localized in the cytoplasm; High confidence in function and specificity; cobalamin adenosyltransferase 3428269 10975572 zobellia_2945 Zobellia galactanivorans cobalamin adenosyltransferase YP_004737371.1 3427688 R 63186 CDS YP_004737372.1 340618919 10975573 complement(3428320..3428481) 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3428481 10975573 zobellia_2946 Zobellia galactanivorans membrane protein YP_004737372.1 3428320 R 63186 CDS YP_004737373.1 340618920 10975574 complement(3428509..3429033) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3429033 10975574 zobellia_2947 Zobellia galactanivorans hypothetical protein YP_004737373.1 3428509 R 63186 CDS YP_004737374.1 340618921 10975575 complement(3429078..3430958) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Contains a duplicated ATPase domain; Belongs to the ABC transporter family, EF3 subfamily; Localized in the cytoplasm near of the cytoplasmic membrane by association with a membrane permease component; Family membership; ABC transporter ATPase 3430958 10975575 zobellia_2948 Zobellia galactanivorans ABC transporter ATPase YP_004737374.1 3429078 R 63186 CDS YP_004737375.1 340618922 10975576 complement(3430963..3432141) 1 NC_015844.1 Signal peptide cleaved between the residues 22 and 23; Contains five transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; hypothetical protein 3432141 10975576 zobellia_2949 Zobellia galactanivorans hypothetical protein YP_004737375.1 3430963 R 63186 CDS YP_004737376.1 340618923 10975577 3432245..3432994 1 NC_015844.1 This enzyme, CDP-diacylglycerol--serine O-phosphatidyltransferase, is involved in phospholipid biosynthesis; Signal peptide cleaved between the residues 24 and 25, Contains six transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity; phosphatidylserine synthase 3432994 pssA 10975577 pssA Zobellia galactanivorans phosphatidylserine synthase YP_004737376.1 3432245 D 63186 CDS YP_004737377.1 340618924 10978394 complement(3432991..3433731) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase) encoded by a different gene of those that encode for the ABC transporter permease component (ABC membrane); Family membership; ABC transporter ATPase 3433731 10978394 zobellia_2951 Zobellia galactanivorans ABC transporter ATPase YP_004737377.1 3432991 R 63186 CDS YP_004737378.1 340618925 10975579 complement(3433822..3434676) 1 NC_015844.1 Required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif. This system mainly transports proteins with bound cofactors that require folding prior to export; Contains six transmembrane segments; High confidence in function and specificity; Sec-independent protein translocase 3434676 tatC 10975579 tatC Zobellia galactanivorans Sec-independent protein translocase YP_004737378.1 3433822 R 63186 CDS YP_004737379.1 340618926 10978641 complement(3434676..3435641) 1 NC_015844.1 Arabinose 5-phosphate isomerase or Phosphoarabinoisomerase is involved in the lipopolysaccharide (LPS) biosynthesis; It catalyzes the interconversion of D-arabinose 5-phosphate and D-ribulose 5-phosphate; Contains a N-terminal SIS (Sugar ISomerase) domain that is a phosphosugar-binding domain and a C-terminal CBS (cystathionine-beta-synthase) domans; Belongs to the SIS family; Localized in the cytoplasm; High confidence in function and specificity; arabinose 5-phosphate isomerase 3435641 kdsD 10978641 kdsD Zobellia galactanivorans arabinose 5-phosphate isomerase YP_004737379.1 3434676 R 63186 CDS YP_004737380.1 340618927 10978058 3435896..3438106 1 NC_015844.1 RecQ is a ATP-dependent DNA helicase involved in genome maintenance in the RecF recombination pathway; RecQ unwinds paired DNA, translocating in a 3' to 5' direction; The expression of RecQ gene is under the regulation of the SOS system. Contains a DEAD/H box and a HRDC domain; Belongs to superfamily II of helicases, RecQ family; Localized in the cytoplasm; High confidence in function and specificity; ATP-dependent DNA helicase RecQ 3438106 recQ2 10978058 recQ2 Zobellia galactanivorans ATP-dependent DNA helicase RecQ YP_004737380.1 3435896 D 63186 CDS YP_004737381.1 340618928 10978448 complement(3438184..3439236) 1 NC_015844.1 Muramoyltetrapeptide carboxypeptidase converts cytosolic UDP-MurNAc-tetrapeptides to tripeptides, the precursors for murein synthesis. Is essential for viability during stationary phase. Belonging to the family S66 of the serine peptidases. The active site is a catalytic triad, Ser, His Glu. Contains a N-terminal transmembrane segment. Localized in the cytoplasmic membrane.; High confidence in function and specificity; muramoyltetrapeptide carboxypeptidase 3439236 ldcA 10978448 ldcA Zobellia galactanivorans muramoyltetrapeptide carboxypeptidase YP_004737381.1 3438184 R 63186 CDS YP_004737382.1 340618929 10978077 complement(3439325..3440662) 1 NC_015844.1 Contains an N-terminal transmembrane segment followed by a carboxypeptidase domain; Localized in the cytoplasmic membrane; hypothetical protein 3440662 10978077 zobellia_2956 Zobellia galactanivorans hypothetical protein YP_004737382.1 3439325 R 63186 CDS YP_004737383.1 340618930 10975580 3440756..3440968 1 NC_015844.1 Hypothetical protein; hypothetical protein 3440968 10975580 zobellia_2957 Zobellia galactanivorans hypothetical protein YP_004737383.1 3440756 D 63186 CDS YP_004737384.1 340618931 10975581 complement(3440965..3441474) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3441474 10975581 zobellia_2958 Zobellia galactanivorans hypothetical protein YP_004737384.1 3440965 R 63186 CDS YP_004737385.1 340618932 10975582 3441504..3441620 1 NC_015844.1 Hypothetical protein; hypothetical protein 3441620 10975582 zobellia_2959 Zobellia galactanivorans hypothetical protein YP_004737385.1 3441504 D 63186 CDS YP_004737386.1 340618933 10975583 complement(3441634..3442362) 1 NC_015844.1 Enzyme responsible for synthesis of pseudouridine from uracil-2604 in 23S ribosomal RNA by rotation of the C1'-N-1 glycosidic bond of uridine to a C1'-C5; Contains a N-terminal S4 RNA-binding domain that probably mediates binding to RNA.; Belongs to the pseudouridine synthase RsuA family; localized in the cytoplasm; High confidence in function and specificity; ribosomal large subunit pseudouridine synthase F 3442362 rluF 10975583 rluF Zobellia galactanivorans ribosomal large subunit pseudouridine synthase F YP_004737386.1 3441634 R 63186 CDS YP_004737387.1 340618934 10978473 complement(3442461..3443684) 1 NC_015844.1 Contains a C-terminal transmembrane helix; Signal peptide cleaved between the residues 22 and 23; Localized in the cytoplasmic membrane; hypothetical protein 3443684 10978473 zobellia_2961 Zobellia galactanivorans hypothetical protein YP_004737387.1 3442461 R 63186 CDS YP_004737388.1 340618935 10975584 complement(3443674..3446034) 1 NC_015844.1 This integral membrane protein encompasses two conserved domains (1-444 and 445-786); Contains 22 transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3446034 10975584 zobellia_2962 Zobellia galactanivorans membrane protein YP_004737388.1 3443674 R 63186 CDS YP_004737389.1 340618936 10975585 complement(3446220..3447371) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3447371 10975585 zobellia_2963 Zobellia galactanivorans lipoprotein YP_004737389.1 3446220 R 63186 CDS YP_004737390.1 340618937 10975586 complement(3447401..3447652) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3447652 10975586 zobellia_2964 Zobellia galactanivorans hypothetical protein YP_004737390.1 3447401 R 63186 CDS YP_004737391.1 340618938 10975587 3447771..3447908 1 NC_015844.1 Hypothetical protein; hypothetical protein 3447908 10975587 zobellia_2965 Zobellia galactanivorans hypothetical protein YP_004737391.1 3447771 D 63186 CDS YP_004737392.1 340618939 10975588 3447851..3448741 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 26 and 27; Localized in the cytoplasmic and/or outer membrane; Conserved hypothetical protein; lipoprotein 3448741 10975588 zobellia_2966 Zobellia galactanivorans lipoprotein YP_004737392.1 3447851 D 63186 CDS YP_004737393.1 340618940 10975589 3448725..3450176 1 NC_015844.1 Peptidyl-prolyl isomerase catalyzes the cis-trans isomerization of proline residues. Also known as chaperone, SurA is involved in the correct folding and assembly of outer membrane proteins such as ompA, ompF and lamB recognizing specific patterns of aromatic residues and the orientation of their side chains. It May act in both early periplasmic and late outer membrane-associated steps of protein maturation. Essential for the survival of bacteria in stationary phase; Signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; High confidence in function and specificity; peptidyl-prolyl isomerase 3450176 surA 10975589 surA Zobellia galactanivorans peptidyl-prolyl isomerase YP_004737393.1 3448725 D 63186 CDS YP_004737394.1 340618941 10978627 3450181..3451134 1 NC_015844.1 MoxR-like ATPases have been proposed to function with VWA domain proteins to form a chaperone system involved in the activation of proteins by primarily mediating the insertion of metal cofactors into the substrate molecules; Belongs to the MoxR-like family; Localized in the cytoplasm; Function unclear; MoxR-like ATPase 3451134 10978627 zobellia_2968 Zobellia galactanivorans MoxR-like ATPase YP_004737394.1 3450181 D 63186 CDS YP_004737395.1 340618942 10975590 3451320..3453587 1 NC_015844.1 Aconitate hydratase is involved in the tricarboxylic acid cycle. It catalyzes the reversible, stereo-specific, isomerization of citrate to isocitrate via cis-aconitate. It displays a N-terminal catalytic domain which binds a 4Fe-4S cluster and a C-terminal domain which undergoes conformational change in the enzyme mechanism; Localized in the cytoplasm; High confidence in function and specificity; aconitate hydratase 3453587 acnA 10975590 acnA Zobellia galactanivorans aconitate hydratase YP_004737395.1 3451320 D 63186 CDS YP_004737396.1 340618943 10977462 3453758..3454213 1 NC_015844.1 Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Belongs to the thioredoxin family; Localized in the cytoplasm; Specificity unclear; thiol-disulfide oxidoreductase 3454213 10977462 zobellia_2970 Zobellia galactanivorans thiol-disulfide oxidoreductase YP_004737396.1 3453758 D 63186 CDS YP_004737397.1 340618944 10975592 3454280..3454780 1 NC_015844.1 Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Belongs to the thioredoxin family; Localized in the cytoplasm; Specificity unclear; thiol-disulfide oxidoreductase 3454780 10975592 zobellia_2971 Zobellia galactanivorans thiol-disulfide oxidoreductase YP_004737397.1 3454280 D 63186 CDS YP_004737398.1 340618945 10975593 complement(3454784..3455239) 1 NC_015844.1 Carotene hydroxylase, involved in the carotenoid biosynthesis, catalyzes the hydroxylation of both beta rings of beta-carotene to form zeaxanthine; Contains three transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity; beta-carotene hydroxylase 3455239 crtZ 10975593 crtZ Zobellia galactanivorans beta-carotene hydroxylase YP_004737398.1 3454784 R 63186 CDS YP_004737399.1 340618946 10977682 complement(3455241..3456080) 1 NC_015844.1 The phytoene synthetase (PSY) catalyzes the conversion of two molecules of geranylgeranyl diphosphate (GGPP) into phytoene. It is the second step in the biosynthesis of carotenoids from isopentenyl diphosphate. The reaction carried out by PSY is catalyzed in two separate steps: the first is a head-to-head condensation of the two molecules of GGPP to form prephytoene diphosphate, this intermediate is then rearranged to form phytoene; Belongs to the phytoene/squalene synthetase family; Localized in the cytoplasm; High confidence in function and specificity; Phytoene synthetase 3456080 crtB 10977682 crtB Zobellia galactanivorans Phytoene synthetase YP_004737399.1 3455241 R 63186 CDS YP_004737400.1 340618947 10977678 complement(3456092..3457549) 1 NC_015844.1 Phytoene dehydrogenase or phytoene desaturase is involved in carotenoid biosynthesis that converts phytoene into zeta-carotene via the symmetrical introduction of two double bonds at the C-11 and C-11' positions of phytoene; Uses the FAD as cofactor; Belongs to the carotenoid/retinoid oxidoreductase family; Possible signal peptide of lipoprotein cleaved between thez residues 18 and 19; Possibly localized in the outer membrane; High confidence in function and specificity; Phytoene dehydrogenase 3457549 crtI 10977678 crtI Zobellia galactanivorans Phytoene dehydrogenase YP_004737400.1 3456092 R 63186 CDS YP_004737401.1 340618948 10977679 complement(3457569..3458468) 1 NC_015844.1 The MerR-type transcriptional regulators contain a helix-turn-helix (HTH) DNA-binding motif involved in the binding of the protein to the operator sequences in the DNA. The HTH domain, located in the N-terminal part of these proteins, is followed by a coiled-coil region. The C-terminal part contains effector binding regions that are specific to the effector recognized; Localized in the cytoplasm; Family membership; MerR-type transcriptional regulator 3458468 10977679 zobellia_2975 Zobellia galactanivorans MerR-type transcriptional regulator YP_004737401.1 3457569 R 63186 CDS YP_004737402.1 340618949 10974045 3458743..3459048 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3459048 10974045 zobellia_2977 Zobellia galactanivorans hypothetical protein YP_004737402.1 3458743 D 63186 CDS YP_004737403.1 340618950 10975595 3459069..3459470 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity which acts as transcriptional regulator; Family membership; two-component system-response regulator, receiver domain 3459470 10975595 zobellia_2978 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004737403.1 3459069 D 63186 CDS YP_004737404.1 340618951 10975596 3459529..3460089 1 NC_015844.1 The HNOB (Heme NO Binding) module, is a predominantly alpha-helical module and binds heme via a covalent linkage to histidine. The HNOB domain is predicted to function as a heme-dependent sensor for gaseous ligands, and transduce diverse downstream signals, in both bacteria and animals; Probably, acts as effector domain belonging to a two-component system; Family membership; heme NO Binding protein 3460089 10975596 zobellia_2979 Zobellia galactanivorans heme NO Binding protein YP_004737404.1 3459529 D 63186 CDS YP_004737405.1 340618952 10975597 3460082..3462073 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains three N-terminal PAS/PAC domains involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 3462073 10975597 zobellia_2980 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004737405.1 3460082 D 63186 CDS YP_004737406.1 340618953 10975599 3462075..3463208 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 3463208 10975599 zobellia_2981 Zobellia galactanivorans hypothetical protein YP_004737406.1 3462075 D 63186 CDS YP_004737407.1 340618954 10975600 3463208..3464266 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Possibly localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 3464266 10975600 zobellia_2982 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004737407.1 3463208 D 63186 CDS YP_004737408.1 340618955 10975601 3464271..3464588 1 NC_015844.1 The histidine-containing phosphotransfer (HPt) domain is a protein module that mediates phosphotransfer reactions in the two-component signaling systems; HPt modules (~120 residues) contain a histidine residue capable of participating in phosphoryl transfer reactions. They serve as a phosphoreceiver and phosphodonor in order to shuttle phosphoryl groups between two or more response regulator domains.; Family membership; histidine-containing phosphotransfer protein 3464588 10975601 zobellia_2983 Zobellia galactanivorans histidine-containing phosphotransfer protein YP_004737408.1 3464271 D 63186 CDS YP_004737409.1 340618956 10975602 3464591..3465316 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, which acts as transcriptional regulator; Family membership; two-component system-response regulator 3465316 10975602 zobellia_2984 Zobellia galactanivorans two-component system-response regulator YP_004737409.1 3464591 D 63186 CDS YP_004737410.1 340618957 10975603 complement(3465709..3467769) 1 NC_015844.1 Protein containing three tetratrico peptide repeats (TPRs). TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Function unclear; hypothetical protein 3467769 10975603 zobellia_2985 Zobellia galactanivorans hypothetical protein YP_004737410.1 3465709 R 63186 CDS YP_004737411.1 340618958 10975604 complement(3468022..3469551) 1 NC_015844.1 Glycoside hydrolases hydrolyze the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non-carbohydrate moiety. Its exact specificity is unknown; Contains a N-terminal transmembrane helix; Belongs to the family 2 of the glycoside hydrolases (GH2); Localized in the cytoplasmic membrane; Specificity unclear; glycoside hydrolase 3469551 10975604 zobellia_2986 Zobellia galactanivorans glycoside hydrolase YP_004737411.1 3468022 R 63186 CDS YP_004737412.1 340618959 10975605 complement(3469548..3470777) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3470777 10975605 zobellia_2987 Zobellia galactanivorans lipoprotein YP_004737412.1 3469548 R 63186 CDS YP_004737413.1 340618960 10975606 complement(3470774..3473860) 1 NC_015844.1 Contains eleven transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3473860 10975606 zobellia_2988 Zobellia galactanivorans membrane protein YP_004737413.1 3470774 R 63186 CDS YP_004737414.1 340618961 10975607 3474421..3475689 1 NC_015844.1 Protein distantly related to the protein Wzx from E. coli which is involved in O-antigen biosynthesis; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3475689 10975607 zobellia_2989 Zobellia galactanivorans membrane protein YP_004737414.1 3474421 D 63186 CDS YP_004737415.1 340618962 10975608 3475757..3476995 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Localized in the cytoplasm., Annotation date: 11.12.2006 18:21:50; Specificity unclear; glycosyltransferase 3476995 10975608 zobellia_2990 Zobellia galactanivorans glycosyltransferase YP_004737415.1 3475757 D 63186 CDS YP_004737416.1 340618963 10975610 3477034..3478173 1 NC_015844.1 Modular protein with a N-terminal response regulator receiver domain and a C-terminal dolichol- phosphate mannose synthase. Response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The response regulator receiver domain is substrate for a histidine protein kinase sensor. Instead of a transcriptional regulator, the C-terminal effector domain is here a dolichol-phosphate mannose synthase. This enzyme belongs to the family 2 of the glycosyltransferase. It catalyses the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.; High confidence in function and specificity; Dolichol-phosphate mannose synthase 3478173 10975610 zobellia_2991 Zobellia galactanivorans Dolichol-phosphate mannose synthase YP_004737416.1 3477034 D 63186 CDS YP_004737417.1 340618964 10975611 3478221..3478889 1 NC_015844.1 Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership; TetR family transcriptional regulator 3478889 10975611 zobellia_2992 Zobellia galactanivorans TetR family transcriptional regulator YP_004737417.1 3478221 D 63186 CDS YP_004737418.1 340618965 10975612 3478957..3479520 1 NC_015844.1 The exact function of this conserved protein is unknown; Belongs to the carboxymuconolactone decarboxylase family; Localized in the cytoplasm; Family membership; carboxymuconolactone decarboxylase family protein 3479520 10975612 zobellia_2993 Zobellia galactanivorans carboxymuconolactone decarboxylase family protein YP_004737418.1 3478957 D 63186 CDS YP_004737419.1 340618966 10975613 3479738..3479842 1 NC_015844.1 Domain conserved in some proteins; Putatively localized in the cytoplasm; hypothetical protein 3479842 10975613 zobellia_2994 Zobellia galactanivorans hypothetical protein YP_004737419.1 3479738 D 63186 CDS YP_004737420.1 340618967 10975614 3479919..3480563 1 NC_015844.1 The exact function of this DsbA-like protein is unknown; Belongs to the Thioredoxin family, DSBA subfamily; Localized in the cytoplasm; Family membership; DSBA thioredoxin family protein 3480563 10975614 zobellia_2995 Zobellia galactanivorans DSBA thioredoxin family protein YP_004737420.1 3479919 D 63186 CDS YP_004737421.1 340618968 10975615 3480896..3482902 1 NC_015844.1 Possible enzyme acting with carbohydrates; Contains one N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3482902 10975615 zobellia_2996 Zobellia galactanivorans membrane protein YP_004737421.1 3480896 D 63186 CDS YP_004737422.1 340618969 10975616 complement(3482924..3484183) 1 NC_015844.1 The small-conductance mechanosensitive channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation; Contains five transmembrane helices; Belongs to the small-conductance MS channels; Localized in the cytoplasmic membrane; Family membership; small-conductance mechanosensitive channel family protein 3484183 10975616 zobellia_2997 Zobellia galactanivorans small-conductance mechanosensitive channel family protein YP_004737422.1 3482924 R 63186 CDS YP_004737423.1 340618970 10975617 complement(3484341..3485189) 1 NC_015844.1 Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains one N-terminal copy of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS-box proteins and bind to DNA; Localized in the cytoplasm; Family membership; universal stress protein 3485189 10975617 zobellia_2998 Zobellia galactanivorans universal stress protein YP_004737423.1 3484341 R 63186 CDS YP_004737424.1 340618971 10975618 3485219..3485344 1 NC_015844.1 Hypothetical protein; hypothetical protein 3485344 10975618 zobellia_2999 Zobellia galactanivorans hypothetical protein YP_004737424.1 3485219 D 63186 CDS YP_004737425.1 340618972 10975619 complement(3485341..3485733) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3485733 10975619 zobellia_3000 Zobellia galactanivorans hypothetical protein YP_004737425.1 3485341 R 63186 CDS YP_004737426.1 340618973 10975622 complement(3486227..3486370) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3486370 10975622 zobellia_3001 Zobellia galactanivorans hypothetical protein YP_004737426.1 3486227 R 63186 CDS YP_004737427.1 340618974 10975623 complement(3486411..3488039) 1 NC_015844.1 Cda is a calcium-dependent ATPase. Vanadate strongly inhibits its activity; Belongs to the alkaline phosphatase clan, type I phosphodiesterase family; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; High confidence in function and specificity; calcium-dependent ATPase 3488039 cda2 10975623 cda2 Zobellia galactanivorans calcium-dependent ATPase YP_004737427.1 3486411 R 63186 CDS YP_004737428.1 340618975 10977640 complement(3488376..3489326) 1 NC_015844.1 Protein that contains a N-terminal Phosphatidylinositol-specific phospholipase X-box domain; Belongs to the glycerophosphoryl diester phosphodiesterase family; Signal peptide of lipoprotein cleaved between the residues 17 and 18; Localized in the outer membrane; Family membership; glycerophosphodiester phosphodiesterase protein family 3489326 10977640 zobellia_3003 Zobellia galactanivorans glycerophosphodiester phosphodiesterase protein family YP_004737428.1 3488376 R 63186 CDS YP_004737429.1 340618976 10975624 complement(3489393..3490781) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 18 and 19; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 3490781 10975624 zobellia_3004 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737429.1 3489393 R 63186 CDS YP_004737430.1 340618977 10975625 complement(3490800..3494243) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a N-terminal carboxypeptidase regulatory domain (117-190), a Plug module (206-316) acting as the channel gate; The signal peptide is cleaved between the residue 22 and 23; Family membership; TonB-dependent transducer 3494243 10975625 zobellia_3005 Zobellia galactanivorans TonB-dependent transducer YP_004737430.1 3490800 R 63186 CDS YP_004737431.1 340618978 10975626 complement(3494422..3495669) 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 3495669 10975626 zobellia_3006 Zobellia galactanivorans anti-sigma factor YP_004737431.1 3494422 R 63186 CDS YP_004737432.1 340618979 10975627 complement(3495760..3496389) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 3496389 10975627 zobellia_3007 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004737432.1 3495760 R 63186 CDS YP_004737433.1 340618980 10975628 complement(3496952..3498151) 1 NC_015844.1 Enzyme involved in the Glycine, serine and threonine metabolism, and in particular, in the glycine catabolism; Also called 2-amino-3-ketobutyrate coenzyme A ligase; Uses the Pyridoxal phosphate as cofactor; Belongs to the class II of the pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity; glycine C-acetyltransferase 3498151 kblA1 10975628 kblA1 Zobellia galactanivorans glycine C-acetyltransferase YP_004737433.1 3496952 R 63186 CDS YP_004737434.1 340618981 10978049 complement(3498136..3499110) 1 NC_015844.1 This enzyme belongs to the NAD-dependent epimerase/dehydratase family, which is included in the Rossmann fold Superfamily. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions; Localized in the cytoplasm; Family membership; NAD-dependent epimerase/dehydratase 3499110 10978049 zobellia_3009 Zobellia galactanivorans NAD-dependent epimerase/dehydratase YP_004737434.1 3498136 R 63186 CDS YP_004737435.1 340618982 10975629 3499276..3499737 1 NC_015844.1 The AsnC/Lrp-type transcriptional regulator family appears to be an important regulatory system of the amino acid metabolism and related processes; Contains a N-terminal DNA binding AsnC/Lrp-type HTH domain. The C-terminal part contains an effector-binding domain and/or an oligomerization domain; Localized in the cytoplasm; Family membership; AsnC/Lrp-type transcriptional regulator 3499737 10975629 zobellia_3010 Zobellia galactanivorans AsnC/Lrp-type transcriptional regulator YP_004737435.1 3499276 D 63186 CDS YP_004737436.1 340618983 10974047 3500325..3500816 1 NC_015844.1 Shikimate kinase catalyzes the fifth step in the biosynthesis of aromatic amino acids from chorismate (the shikimate pathway). The enzyme catalyzes the reaction: ATP + shikimate = ADP + shikimate-3-phosphate. Shikimate kinaseis found in bacteria, plants and fungi, but not in metazoans. AroK adopts an alpha/beta fold, consisting of a central sheet of five parallel beta-strands flanked by alpha-helices. It binds one magnesium ion. Localized in the cytoplasm.; High confidence in function and specificity; shikimate kinase 3500816 aroK 10974047 aroK Zobellia galactanivorans shikimate kinase YP_004737436.1 3500325 D 63186 CDS YP_004737437.1 340618984 10977549 complement(3500808..3501305) 1 NC_015844.1 PyrR regulates transcriptional attenuation of the pyrimidine nucleotide operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. Forms momodimer and homohexamer in equilibrium. Localized in the cytoplasm.; High confidence in function and specificity; bifunctional protein PyrR 3501305 pyrR2 10977549 pyrR2 Zobellia galactanivorans bifunctional protein PyrR YP_004737437.1 3500808 R 63186 CDS YP_004737438.1 340618985 10978425 complement(3501359..3501760) 1 NC_015844.1 HSP15 is involved in the recycling of free 50S ribosomal subunits that still carry a nascent chain. Binds RNA more specifically than DNA. Binds with very high affinity to the free 50S ribosomal subunit. Does not bind it when it is part of the 70S ribosome; Induced by heat shock; Contains a S4 RNA-binding domain; Belongs to the HSP15 family; Localized in the cytoplasm; High confidence in function and specificity; heat shock protein 15 3501760 hslR 10978425 hslR Zobellia galactanivorans heat shock protein 15 YP_004737438.1 3501359 R 63186 CDS YP_004737439.1 340618986 10978000 3501838..3502755 1 NC_015844.1 Peptidyl-prolyl cis-trans isomerase, or PPIase or rotamase, accelerates the folding of proteins. It catalyzes the peptidyl-prolyl isomerisation during which the peptide bond preceding proline is stabilised in the cis conformation in oligopeptides; Contains a C-terminal calcium binding EF-hand type domain; Lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; High confidence in function and specificity; FKBP-type peptidyl-prolyl cis-trans isomerase 3502755 fklA 10978000 fklA Zobellia galactanivorans FKBP-type peptidyl-prolyl cis-trans isomerase YP_004737439.1 3501838 D 63186 CDS YP_004737440.1 340618987 10977831 complement(3502847..3503440) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3503440 10977831 zobellia_3017 Zobellia galactanivorans periplasmic protein YP_004737440.1 3502847 R 63186 CDS YP_004737441.1 340618988 10975632 complement(3503488..3504441) 1 NC_015844.1 Transketolase (TK) catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5- phosphate to an aldose receptor, such as ribose 5- phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. TK provides a link between the Embden-Meyerhof and pentose-phosphate (Non-oxidative phase) pathways; Uses calcium ion as a cofactor and thiamine diphosphate as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity; transketolase subunit B 3504441 tktB 10975632 tktB Zobellia galactanivorans transketolase subunit B YP_004737441.1 3503488 R 63186 CDS YP_004737442.1 340618989 10978665 complement(3504503..3505348) 1 NC_015844.1 Transketolase (TK) catalyzes the reversible transfer of a two-carbon ketol unit from xylulose 5- phosphate to an aldose receptor, such as ribose 5- phosphate, to form sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. TK provides a link between the Embden-Meyerhof and pentose-phosphate (Non-oxidative phase) pathways; Uses calcium ion as a cofactor and thiamine diphosphate as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity; transketolase subunit A 3505348 tktA 10978665 tktA Zobellia galactanivorans transketolase subunit A YP_004737442.1 3504503 R 63186 CDS YP_004737443.1 340618990 10978664 3505610..3506770 1 NC_015844.1 Queuine tRNA-ribosyltransferase exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4, 5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7- deazaguanosine). Binds one Zinc ion as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; Queuine tRNA-ribosyltransferase 3506770 tgt 10978664 tgt Zobellia galactanivorans Queuine tRNA-ribosyltransferase YP_004737443.1 3505610 D 63186 CDS YP_004737444.1 340618991 10978647 3506770..3507852 1 NC_015844.1 Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3507852 10978647 zobellia_3021 Zobellia galactanivorans membrane protein YP_004737444.1 3506770 D 63186 CDS YP_004737445.1 340618992 10975634 3507873..3508766 1 NC_015844.1 Integral membrane protein belonging to the DUF6 family. Features ten transmembrane helices. Localized in the cytoplasmic membrane.; Family membership; hypothetical protein 3508766 10975634 zobellia_3022 Zobellia galactanivorans hypothetical protein YP_004737445.1 3507873 D 63186 CDS YP_004737446.1 340618993 10975635 3508815..3509768 1 NC_015844.1 The carboxyl transferase subunit alpha is a part of the Acetyl-coenzyme A carboxylase complex that catalyzes the first step in long-chain fatty acid biosynthesis. the complex is a heterohexamer of biotin carboxyl carrier protein (accB), biotin carboxylase (accC) and two subunits each of carboxyl transferase subunit alpha and subunit beta (accD). First, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA; Localized in the cytoplasm.; High confidence in function and specificity; acetyl-coenzyme A carboxylase, carboxyl transferase subunit alpha 3509768 accA 10975635 accA Zobellia galactanivorans acetyl-coenzyme A carboxylase, carboxyl transferase subunit alpha YP_004737446.1 3508815 D 63186 CDS YP_004737447.1 340618994 10977458 3509924..3511471 1 NC_015844.1 DnaB is a helicase that interacts with the DnaG primase and other factors to form the replisome. DnaB participates in initiation and elongation during chromosome replication unwinding the DNA duplex at the chromosome replication fork. It exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins; Forms a homohexamer; Contains a SF4 helicase domain; Belongs to the helicase family, DnaB subfamily; Localized in the cytoplasm; High confidence in function and specificity; replicative DNA helicase 3511471 dnaB 10977458 dnaB Zobellia galactanivorans replicative DNA helicase YP_004737447.1 3509924 D 63186 CDS YP_004737448.1 340618995 10977749 3511580..3512845 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3512845 10977749 zobellia_3025 Zobellia galactanivorans periplasmic protein YP_004737448.1 3511580 D 63186 CDS YP_004737449.1 340618996 10975636 complement(3512889..3515084) 1 NC_015844.1 Oxidoreductase that contains in its C-terminal, a flavodoxin-like domain with a flavin mononucleotide (FMN)-binding site and a NAD-binding domain. In its N-terminal part there are four transmembrane segemnts; Belongs to the Flavoprotein pyridine nucleotide cytochrome reductase family; Localized in the cytoplasmic membrane; Specificity unclear; NADPH oxidoreductase 3515084 10975636 zobellia_3026 Zobellia galactanivorans NADPH oxidoreductase YP_004737449.1 3512889 R 63186 CDS YP_004737450.1 340618997 10975637 complement(3515090..3515587) 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3515587 10975637 zobellia_3027 Zobellia galactanivorans membrane protein YP_004737450.1 3515090 R 63186 CDS YP_004737451.1 340618998 10975638 complement(3515594..3517099) 1 NC_015844.1 The ankyrin repeat is involved in protein-protein interaction. The repeats stack together to form an L-shaped structure; Contains eleven ankyrin repeats; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Function unclear; ankyrin repeat-containing protein 3517099 10975638 zobellia_3028 Zobellia galactanivorans ankyrin repeat-containing protein YP_004737451.1 3515594 R 63186 CDS YP_004737452.1 340618999 10975639 complement(3517188..3518567) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 23 and 24; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3518567 10975639 zobellia_3029 Zobellia galactanivorans lipoprotein YP_004737452.1 3517188 R 63186 CDS YP_004737453.1 340619000 10975640 complement(3518588..3521002) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations. Contains a carboxypeptidase regulatory domain (23-103) and the Plug module (120-225) acting as a channel gate. The signal peptide is cleaved between the residues 17 and 18.; Family membership; TonB-dependent Receptor 3521002 10975640 zobellia_3030 Zobellia galactanivorans TonB-dependent Receptor YP_004737453.1 3518588 R 63186 CDS YP_004737454.1 340619001 10975642 3521128..3522108 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 3522108 10975642 zobellia_3031 Zobellia galactanivorans AraC family transcriptional regulator YP_004737454.1 3521128 D 63186 CDS YP_004737455.1 340619002 10975643 3522232..3524178 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 3524178 10975643 zobellia_3032 Zobellia galactanivorans hypothetical protein YP_004737455.1 3522232 D 63186 CDS YP_004737456.1 340619003 10975644 3524175..3524579 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 3524579 10975644 zobellia_3033 Zobellia galactanivorans hypothetical protein YP_004737456.1 3524175 D 63186 CDS YP_004737457.1 340619004 10975645 complement(3524595..3525401) 1 NC_015844.1 Catalyzes, in presence of Magnesium, the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo; Belongs to the HAD (Haloacid dehalogenase)-like hydrolase superfamily, class II family, class IIB subfamily; Localized in the cytoplasm; High confidence in function and specificity; Sugar phosphatase SupH 3525401 supH 10975645 supH Zobellia galactanivorans Sugar phosphatase SupH YP_004737457.1 3524595 R 63186 CDS YP_004737458.1 340619005 10978626 3525489..3525911 1 NC_015844.1 Protein of unknown function; Belong to the UPF0047 family; Localized in the cytoplasm; hypothetical protein 3525911 yjbQ 10978626 yjbQ Zobellia galactanivorans hypothetical protein YP_004737458.1 3525489 D 63186 CDS YP_004737459.1 340619006 10978788 complement(3525965..3526309) 1 NC_015844.1 Ribosomal protein L20 is one of the proteins from the large ribosomal subunit (50S). L20 is known to bind directly to the 23S rRNA and is required for ribosome assembly, but does not take part in protein synthesis; Belongs to the ribosomal protein L20p family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L20 3526309 rplT 10978788 rplT Zobellia galactanivorans 50S ribosomal protein L20 YP_004737459.1 3525965 R 63186 CDS YP_004737460.1 340619007 10978510 complement(3526398..3526595) 1 NC_015844.1 L35 is a basic protein from the large subunit (50S) of the ribosome; Like many basic polypeptides, L35 completely inhibits ornithine decarboxylase when present unbound in the cell, but the inhibitory function is abolished upon its incorporation into ribosomes; Belongs to the ribosomal protein L35p family; Localized in the cytoplasm; High confidence in function and specificity; 50S ribosomal protein L35 3526595 rpmI 10978510 rpmI Zobellia galactanivorans 50S ribosomal protein L35 YP_004737460.1 3526398 R 63186 CDS YP_004737461.1 340619008 10978523 complement(3526700..3527161) 1 NC_015844.1 IF-3 is thought to function as a fidelity factor during the assembly of the ternary initiation complex which consist of the 30S ribosomal subunit, the initiator tRNA and the messenger RNA. IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. IF- 3 is also a translational repressor protein, it controls the translation of its own gene by binding to its mRNA; Localized in the cytoplasm; High confidence in function and specificity; translation initiation factor IF-3 3527161 infC 10978523 infC Zobellia galactanivorans translation initiation factor IF-3 YP_004737461.1 3526700 R 63186 CDS YP_004737462.1 340619009 10978038 complement(3527287..3529233) 1 NC_015844.1 ThrRS is a homodimeric tRNA synthetase that couples threonine to the 3'OH group of ribose of its cognate tRNA; ThrRS controls also the translation of its own gene by binding to its mRNA; Contains a C-terminal domain that recognizes the anticodon bases, and an N- terminal TGS domain that contributes also to the precise recognition of tRNA(Thr) by interaction with the tRNA acceptor arm along with an adjacent N-terminal domain; Belongs to the class-II aminoacyl-tRNA synthetase family; Localized in the cytoplasm; High confidence in function and specificity; threonyl-tRNA synthetase 3529233 thrS 10978038 thrS Zobellia galactanivorans threonyl-tRNA synthetase YP_004737462.1 3527287 R 63186 CDS YP_004737463.1 340619010 10978660 3529600..3529854 1 NC_015844.1 Possibly localized in the cytoplasm; hypothetical protein 3529854 10978660 zobellia_3040 Zobellia galactanivorans hypothetical protein YP_004737463.1 3529600 D 63186 CDS YP_004737464.1 340619011 10974019 3535519..3537405 1 NC_015844.1 Contains an N-terminal domain of unknown function DUF 1080; Lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Hypothetical protein; hypothetical protein 3537405 10974019 zobellia_3046 Zobellia galactanivorans hypothetical protein YP_004737464.1 3535519 D 63186 CDS YP_004737465.1 340619012 10975647 3537418..3539367 1 NC_015844.1 Large conserved protein that Seems to contain an N-terminal transmembrane segment and a C-terminal Blue (type 1) copper domain from the plastocyanin/azurin family; Putatively localized in the cytoplasmic membrane; Conserved hypothetical protein; azurin-containing protein 3539367 10975647 zobellia_3047 Zobellia galactanivorans azurin-containing protein YP_004737465.1 3537418 D 63186 CDS YP_004737466.1 340619013 10975648 3539403..3540035 1 NC_015844.1 Hemolysin that could to function as a membrane channel; Contains seven transmembrane segments; Belongs to the Hly-III family; Localized in the cytoplasmic membrane; High confidence in function and specificity; hemolysin III 3540035 10975648 zobellia_3048 Zobellia galactanivorans hemolysin III YP_004737466.1 3539403 D 63186 CDS YP_004737467.1 340619014 10975649 3540079..3542310 1 NC_015844.1 Large protein containing a C-terminal cytochrome C domain. Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes; Contains a putative lipoprotein signal peptide cleaved between the residues 19 and 20; Possibly localized in the outer membrane; Family membership; cytochrome c-containing protein 3542310 10975649 zobellia_3049 Zobellia galactanivorans cytochrome c-containing protein YP_004737467.1 3540079 D 63186 CDS YP_004737468.1 340619015 10975650 complement(3542315..3543130) 1 NC_015844.1 It is not clear if this protein of unknown function is a lipoprotein localized in the outer membrane or protein exported in the pepriplasmic space; hypothetical protein 3543130 10975650 zobellia_3050 Zobellia galactanivorans hypothetical protein YP_004737468.1 3542315 R 63186 CDS YP_004737469.1 340619016 10975651 complement(3543165..3543515) 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 3543515 10975651 zobellia_3051 Zobellia galactanivorans hypothetical protein YP_004737469.1 3543165 R 63186 CDS YP_004737470.1 340619017 10975652 3543612..3544001 1 NC_015844.1 Sequence that is found in the conserved part of the barrel structure of a TonB-dependent receptor; Putatively localized in the cytoplasm; hypothetical protein 3544001 10975652 zobellia_3052 Zobellia galactanivorans hypothetical protein YP_004737470.1 3543612 D 63186 CDS YP_004737471.1 340619018 10975653 complement(3544335..3545720) 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 3545720 10975653 zobellia_3053 Zobellia galactanivorans hypothetical protein YP_004737471.1 3544335 R 63186 CDS YP_004737472.1 340619019 10975654 3546111..3546356 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3546356 10975654 zobellia_3054 Zobellia galactanivorans hypothetical protein YP_004737472.1 3546111 D 63186 CDS YP_004737473.1 340619020 10975655 3546808..3547320 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 3547320 10975655 zobellia_3055 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004737473.1 3546808 D 63186 CDS YP_004737474.1 340619021 10975656 3547856..3548536 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 3548536 10975656 zobellia_3056 Zobellia galactanivorans hypothetical protein YP_004737474.1 3547856 D 63186 CDS YP_004737475.1 340619022 10975657 complement(3548598..3550499) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains seven N-terminal tetratrico peptide repeats (TPR) and two transmembrane segments; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 3550499 10975657 zobellia_3057 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004737475.1 3548598 R 63186 CDS YP_004737476.1 340619023 10975658 complement(3550496..3550933) 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to family 11 of transposases; Localized in the cytoplasm; Family membership; transposase, family 11 3550933 10975658 zobellia_3058 Zobellia galactanivorans transposase, family 11 YP_004737476.1 3550496 R 63186 CDS YP_004737477.1 340619024 10975659 complement(3551164..3551826) 1 NC_015844.1 Response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA- binding activity (here, a LuxR-type HTH domain) that acts as transcriptional regulator; Family membership; two-component system-response regulator 3551826 10975659 zobellia_3059 Zobellia galactanivorans two-component system-response regulator YP_004737477.1 3551164 R 63186 CDS YP_004737478.1 340619025 10975660 complement(3551918..3552127) 1 NC_015844.1 Sequence representing the C-terminal part of transposase that could be an insertion sequence (IS). The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Contains a integrase catalytic domain; Belongs to the family 8 of transposases; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 3552127 10975660 zobellia_3060 Zobellia galactanivorans hypothetical protein YP_004737478.1 3551918 R 63186 CDS YP_004737479.1 340619026 10975662 complement(3552088..3552339) 1 NC_015844.1 Sequence representing the central part of transposase. The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site- specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 8 of transposases; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 3552339 10975662 zobellia_3061 Zobellia galactanivorans hypothetical protein YP_004737479.1 3552088 R 63186 CDS YP_004737480.1 340619027 10975663 complement(3552341..3552493) 1 NC_015844.1 Sequence representing the central part of transposase. The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site- specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 8 of transposases; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 3552493 10975663 zobellia_3062 Zobellia galactanivorans hypothetical protein YP_004737480.1 3552341 R 63186 CDS YP_004737481.1 340619028 10975664 complement(3552763..3553059) 1 NC_015844.1 Sequence representing the N-terminal part of transposase that could be an insertion sequence (IS). The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Contains a integrase catalytic domain; Belongs to the family 8 of transposases; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 3553059 10975664 zobellia_3063 Zobellia galactanivorans hypothetical protein YP_004737481.1 3552763 R 63186 CDS YP_004737482.1 340619029 10975665 3553451..3556945 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain (50-101)) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (106-180) and a Plug module (197-327) acting as the channel gate; The signal peptide is cleaved between the residue 22 and 23; Family membership; TonB-dependent transducer 3556945 10975665 zobellia_3064 Zobellia galactanivorans TonB-dependent transducer YP_004737482.1 3553451 D 63186 CDS YP_004737483.1 340619030 10975666 3556950..3558446 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 3558446 10975666 zobellia_3065 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737483.1 3556950 D 63186 CDS YP_004737484.1 340619031 10975667 3558508..3559830 1 NC_015844.1 This protein is homologous to chitinases but the catalytic acidic residues are replaced by polar residues. It likely binds chitin or chitin-derived oligosaccharides; Belongs to the family 18 of the glycoside hydrolases (GH18); Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Function unclear; chitin-binding lectin 3559830 10975667 zobellia_3066 Zobellia galactanivorans chitin-binding lectin YP_004737484.1 3558508 D 63186 CDS YP_004737485.1 340619032 10975668 3560113..3560433 1 NC_015844.1 Protein that corresponds to a fragment of receveir domains present in the response regulators of the LytR/AlgR family; Putatively localized in the cytoplasm; hypothetical protein 3560433 10975668 zobellia_3067 Zobellia galactanivorans hypothetical protein YP_004737485.1 3560113 D 63186 CDS YP_004737486.1 340619033 10975669 3561435..3562847 1 NC_015844.1 Contains a N-terminal J domain present in the DnaJ protein; Localized in the cytoplasm; hypothetical protein 3562847 10975669 zobellia_3068 Zobellia galactanivorans hypothetical protein YP_004737486.1 3561435 D 63186 CDS YP_004737487.1 340619034 10975670 complement(3563264..3563380) 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Localized in the cytoplasm; Hypothetical protein; hypothetical protein 3563380 10975670 zobellia_3069 Zobellia galactanivorans hypothetical protein YP_004737487.1 3563264 R 63186 CDS YP_004737488.1 340619035 10975671 3563400..3563609 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3563609 10975671 zobellia_3070 Zobellia galactanivorans hypothetical protein YP_004737488.1 3563400 D 63186 CDS YP_004737489.1 340619036 10975673 complement(3563647..3564486) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 3564486 10975673 zobellia_3071 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004737489.1 3563647 R 63186 CDS YP_004737490.1 340619037 10975674 3564850..3564957 1 NC_015844.1 Hypothetical protein; hypothetical protein 3564957 10975674 zobellia_3072 Zobellia galactanivorans hypothetical protein YP_004737490.1 3564850 D 63186 CDS YP_004737491.1 340619038 10975675 complement(3565010..3565423) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3565423 10975675 zobellia_3073 Zobellia galactanivorans hypothetical protein YP_004737491.1 3565010 R 63186 CDS YP_004737492.1 340619039 10975676 3565735..3567234 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3567234 10975676 zobellia_3074 Zobellia galactanivorans hypothetical protein YP_004737492.1 3565735 D 63186 CDS YP_004737493.1 340619040 10975677 3567517..3567657 1 NC_015844.1 Hypothetical protein; hypothetical protein 3567657 10975677 zobellia_3075 Zobellia galactanivorans hypothetical protein YP_004737493.1 3567517 D 63186 CDS YP_004737494.1 340619041 10975678 complement(3567738..3568199) 1 NC_015844.1 Protein that is the C-terminal part of a transposases that consists to an integrase domain. The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 8 of transposases; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 3568199 10975678 zobellia_3076 Zobellia galactanivorans hypothetical protein YP_004737494.1 3567738 R 63186 CDS YP_004737495.1 340619042 10975679 complement(3568531..3568656) 1 NC_015844.1 Protein that is the N-terminal part of a transposases. The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 8 of transposases; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 3568656 10975679 zobellia_3077 Zobellia galactanivorans hypothetical protein YP_004737495.1 3568531 R 63186 CDS YP_004737496.1 340619043 10975680 complement(3568758..3569387) 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 3569387 10975680 zobellia_3078 Zobellia galactanivorans hypothetical protein YP_004737496.1 3568758 R 63186 CDS YP_004737497.1 340619044 10975681 complement(3569728..3569985) 1 NC_015844.1 Probable fragment of protein that binds ATP; Seems to belong to the ATPase P-loop family; Hypothetical protein; hypothetical protein 3569985 10975681 zobellia_3079 Zobellia galactanivorans hypothetical protein YP_004737497.1 3569728 R 63186 CDS YP_004737498.1 340619045 10975682 complement(3570257..3570679) 1 NC_015844.1 Putatively localized in the cytoplasmic membrane via a transmembrane segment; hypothetical protein 3570679 10975682 zobellia_3080 Zobellia galactanivorans hypothetical protein YP_004737498.1 3570257 R 63186 CDS YP_004737499.1 340619046 10975683 complement(3572175..3572420) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3572420 10975683 zobellia_3081 Zobellia galactanivorans hypothetical protein YP_004737499.1 3572175 R 63186 CDS YP_004737500.1 340619047 10975684 3572626..3574554 1 NC_015844.1 This protein has a modular architecture composed of a N-terminal TPR motif, a central beta-propeller domain, encompassing four WD40 repeats, and a C-terminal OmpA domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan. The tetratrico peptide repeat (TPR) is a structural motif, which mediates proteinprotein interactions; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space and/or in the outer membrane; Family membership; OmpA-like periplasmic protein 3574554 10975684 zobellia_3082 Zobellia galactanivorans OmpA-like periplasmic protein YP_004737500.1 3572626 D 63186 CDS YP_004737501.1 340619048 10975685 3574771..3575583 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3575583 10975685 zobellia_3083 Zobellia galactanivorans hypothetical protein YP_004737501.1 3574771 D 63186 CDS YP_004737502.1 340619049 10975686 3575749..3576039 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 3576039 10975686 zobellia_3084 Zobellia galactanivorans hypothetical protein YP_004737502.1 3575749 D 63186 CDS YP_004737503.1 340619050 10975687 3576185..3577090 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 3577090 10975687 zobellia_3085 Zobellia galactanivorans hypothetical protein YP_004737503.1 3576185 D 63186 CDS YP_004737504.1 340619051 10975688 3577578..3579212 1 NC_015844.1 Protein containing a N-terminal Rieske [2Fe-2S] domain and a C-terminal domain Localized in the cytoplasm.; Function unclear; FMN / Fe-S cluster binding protein 3579212 10975688 zobellia_3086 Zobellia galactanivorans FMN / Fe-S cluster binding protein YP_004737504.1 3577578 D 63186 CDS YP_004737505.1 340619052 10975689 complement(3579307..3580005) 1 NC_015844.1 This protein corresponds to the C-terminal region of a transposase and is likely inactive; The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the transposase mutator family; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 3580005 10975689 zobellia_3087 Zobellia galactanivorans hypothetical protein YP_004737505.1 3579307 R 63186 CDS YP_004737506.1 340619053 10975690 complement(3580094..3580492) 1 NC_015844.1 Protein that corresponds to the N-terminal region of a transposase; The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the transposase mutator family; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 3580492 10975690 zobellia_3088 Zobellia galactanivorans hypothetical protein YP_004737506.1 3580094 R 63186 CDS YP_004737507.1 340619054 10975691 complement(3580591..3582663) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3582663 10975691 zobellia_3089 Zobellia galactanivorans hypothetical protein YP_004737507.1 3580591 R 63186 CDS YP_004737508.1 340619055 10975692 complement(3582691..3582906) 1 NC_015844.1 Protein fragment found in various UDP-N-acetylmuramyl pentapeptide synthases; Contains an N-terminal UDP-N-acetylmuramyl pentapeptide synthases domain; Putatively localized in the cytoplasm; hypothetical protein 3582906 10975692 zobellia_3090 Zobellia galactanivorans hypothetical protein YP_004737508.1 3582691 R 63186 CDS YP_004737509.1 340619056 10975694 complement(3582888..3583409) 1 NC_015844.1 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase (MurF) is an enzyme involved in the final step of the biosynthesis of peptidoglycan which catalyzes the addition of D-alanyl-D-alanine to the nucleotide precursor UDP-N- acetylmuramoyl-L-alanyl-D-glutamyl-meso-2, 6-diaminoheptanedioate; Belongs to the MurCDEF family; This sequence is the N-terminal catalytic domain of MurF only; Localized in the cytoplasm; High confidence in function and specificity; UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase, catalytic domain 3583409 murF2 10975694 murF2 Zobellia galactanivorans UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase, catalytic domain YP_004737509.1 3582888 R 63186 CDS YP_004737510.1 340619057 10978205 complement(3583387..3583482) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3583482 10978205 zobellia_3092 Zobellia galactanivorans hypothetical protein YP_004737510.1 3583387 R 63186 CDS YP_004737511.1 340619058 10975695 complement(3583466..3584074) 1 NC_015844.1 TraK is part of a conjugative transposon and is predicted to be involved in its transfer; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane.; Function unclear; conjugative transposon protein TraK 3584074 traK 10975695 traK Zobellia galactanivorans conjugative transposon protein TraK YP_004737511.1 3583466 R 63186 CDS YP_004737512.1 340619059 10978680 complement(3584136..3584384) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3584384 10978680 zobellia_3094 Zobellia galactanivorans hypothetical protein YP_004737512.1 3584136 R 63186 CDS YP_004737513.1 340619060 10975696 complement(3584403..3584696) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3584696 10975696 zobellia_3095 Zobellia galactanivorans hypothetical protein YP_004737513.1 3584403 R 63186 CDS YP_004737514.1 340619061 10975697 complement(3584708..3584986) 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3584986 10975697 zobellia_3096 Zobellia galactanivorans hypothetical protein YP_004737514.1 3584708 R 63186 CDS YP_004737515.1 340619062 10975698 complement(3585304..3585651) 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Putatively localized in the cytoplasm; Hypothetical protein; hypothetical protein 3585651 10975698 zobellia_3097 Zobellia galactanivorans hypothetical protein YP_004737515.1 3585304 R 63186 CDS YP_004737516.1 340619063 10975699 3586009..3588015 1 NC_015844.1 MobC is part of the conjugative transposon CTn341, first identified in Bacteroides strains. It is involved in the transfer and mobilization of CTn341; Belongs to the TraG/TraD family; Contain a P-loop and walker-B site for nucleotide binding and five transmembrane helices; Localized in the cytoplasmic membrane; Function unclear; Putative mobilization protein MobC 3588015 mobC 10975699 mobC Zobellia galactanivorans Putative mobilization protein MobC YP_004737516.1 3586009 D 63186 CDS YP_004737517.1 340619064 10978169 3588151..3588705 1 NC_015844.1 Peptidase family M23 mainly contains endopeptidases that hydrolyze bacterial cell wall peptidoglycans. One catalytic zinc ion is bound per peptidase molecule. The cation ligands occur in the conserved motifs HXXXD and HXH. The first histidine of the second motif is also involved in the catalysis; Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Specificity unclear; metallopeptidase 3588705 10978169 zobellia_3099 Zobellia galactanivorans metallopeptidase YP_004737517.1 3588151 D 63186 CDS YP_004737518.1 340619065 10975700 3588732..3588938 1 NC_015844.1 Hypothetical protein; hypothetical protein 3588938 10975700 zobellia_3100 Zobellia galactanivorans hypothetical protein YP_004737518.1 3588732 D 63186 CDS YP_004737519.1 340619066 10975702 3588942..3589964 1 NC_015844.1 TraM is part of a conjugative transposon and is predicted to be involved in its transfer; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Function unclear; conjugative transposon protein TraM 3589964 traM 10975702 traM Zobellia galactanivorans conjugative transposon protein TraM YP_004737519.1 3588942 D 63186 CDS YP_004737520.1 340619067 10978681 3589954..3592293 1 NC_015844.1 TraG is part of the conjugative transposon and likely involved in its transfer; Localized in the cytoplasm; Function unclear; conjugative transposon protein TraG 3592293 traG 10978681 traG Zobellia galactanivorans conjugative transposon protein TraG YP_004737520.1 3589954 D 63186 CDS YP_004737521.1 340619068 10978678 3592302..3593135 1 NC_015844.1 TraN is part of the conjugative transposon and likely involved in its transfer; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Function unclear; conjugative transposon protein TraN 3593135 traN 10978678 traN Zobellia galactanivorans conjugative transposon protein TraN YP_004737521.1 3592302 D 63186 CDS YP_004737522.1 340619069 10978682 3593241..3593735 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3593735 10978682 zobellia_3104 Zobellia galactanivorans hypothetical protein YP_004737522.1 3593241 D 63186 CDS YP_004737523.1 340619070 10975703 3593766..3594077 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3594077 10975703 zobellia_3105 Zobellia galactanivorans hypothetical protein YP_004737523.1 3593766 D 63186 CDS YP_004737524.1 340619071 10975704 3594084..3594590 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 3594590 10975704 zobellia_3106 Zobellia galactanivorans hypothetical protein YP_004737524.1 3594084 D 63186 CDS YP_004737525.1 340619072 10975705 3594838..3595446 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 3595446 10975705 zobellia_3107 Zobellia galactanivorans hypothetical protein YP_004737525.1 3594838 D 63186 CDS YP_004737526.1 340619073 10975706 3595514..3596071 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 3596071 10975706 zobellia_3108 Zobellia galactanivorans hypothetical protein YP_004737526.1 3595514 D 63186 CDS YP_004737527.1 340619074 10975707 3596095..3596622 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3596622 10975707 zobellia_3109 Zobellia galactanivorans hypothetical protein YP_004737527.1 3596095 D 63186 CDS YP_004737528.1 340619075 10975708 3596633..3597184 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3597184 10975708 zobellia_3110 Zobellia galactanivorans hypothetical protein YP_004737528.1 3596633 D 63186 CDS YP_004737529.1 340619076 10975710 3597190..3598065 1 NC_015844.1 TraJ is part of a conjugative transposon and is predicted to be involved in its transfer. Contains six transmembrane helices. Localized in the cytoplasmic membrane.; Function unclear; conjugative transposon proteinTraJ 3598065 traJ 10975710 traJ Zobellia galactanivorans conjugative transposon proteinTraJ YP_004737529.1 3597190 D 63186 CDS YP_004737530.1 340619077 10978679 complement(3598600..3600138) 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, would interact with the N-terminal extension found in the TonB-dependant transducers; Contains one transmembrane segment; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 3600138 10978679 zobellia_3112 Zobellia galactanivorans anti-sigma factor YP_004737530.1 3598600 R 63186 CDS YP_004737531.1 340619078 10975711 complement(3600351..3601139) 1 NC_015844.1 Protein representing the C-terminal part of transposase that could be an insertion sequence (IS). The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Contains a integrase catalytic domain; Belongs to the family 8 of transposases; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 3601139 10975711 zobellia_3113 Zobellia galactanivorans hypothetical protein YP_004737531.1 3600351 R 63186 CDS YP_004737532.1 340619079 10975712 complement(3601201..3601479) 1 NC_015844.1 Protein representing the N-terminal part of transposase that could be an insertion sequence (IS). The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 8 of transposases; Localized in the cytoplasm; High confidence in function and specificity; hypothetical protein 3601479 10975712 zobellia_3114 Zobellia galactanivorans hypothetical protein YP_004737532.1 3601201 R 63186 CDS YP_004737533.1 340619080 10975713 3601930..3602022 1 NC_015844.1 Hypothetical protein; hypothetical protein 3602022 10975713 zobellia_3115 Zobellia galactanivorans hypothetical protein YP_004737533.1 3601930 D 63186 CDS YP_004737534.1 340619081 10975714 3602230..3602331 1 NC_015844.1 Hypothetical protein; hypothetical protein 3602331 10975714 zobellia_3116 Zobellia galactanivorans hypothetical protein YP_004737534.1 3602230 D 63186 CDS YP_004737535.1 340619082 10975715 complement(3602613..3603527) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3603527 10975715 zobellia_3117 Zobellia galactanivorans periplasmic protein YP_004737535.1 3602613 R 63186 CDS YP_004737536.1 340619083 10975716 complement(3603543..3604559) 1 NC_015844.1 The LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of operons; They contain a N-terminal lacI-type HTH domain involved in the binding of the protein to the operator sequences in the DNA and a C- terminal periplasmic binding protein domain that are the primary receptors for chemotaxis and transport of many sugar based solutes that act as inducers; Localized in the cytoplasm; Family membership; LacI-type transcriptional regulator 3604559 10975716 zobellia_3118 Zobellia galactanivorans LacI-type transcriptional regulator YP_004737536.1 3603543 R 63186 CDS YP_004737537.1 340619084 10975717 3604808..3607939 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (34-108) and the Plug module (124-231) acting as a channel gate; The signal peptide is cleaved between the residues 30 and 31; Family membership; TonB-dependent Receptor 3607939 10975717 zobellia_3119 Zobellia galactanivorans TonB-dependent Receptor YP_004737537.1 3604808 D 63186 CDS YP_004737538.1 340619085 10975718 3607959..3609815 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 25 and 26; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 3609815 10975718 zobellia_3120 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737538.1 3607959 D 63186 CDS YP_004737539.1 340619086 10975720 3609935..3611128 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 3611128 10975720 zobellia_3121 Zobellia galactanivorans hypothetical protein YP_004737539.1 3609935 D 63186 CDS YP_004737540.1 340619087 10975721 3611146..3612522 1 NC_015844.1 NAD(P)-dependent dehydrogenase that belongs to the Rossmann fold family; Contains a twin-arginine translocation signal peptide; Localized in the periplasmic space; Specificity unclear; NAD(P)-dependent dehydrogenase 3612522 10975721 zobellia_3122 Zobellia galactanivorans NAD(P)-dependent dehydrogenase YP_004737540.1 3611146 D 63186 CDS YP_004737541.1 340619088 10975722 3612644..3614023 1 NC_015844.1 Contains a signal peptide of lipoprotein cleaved between the residues 15 and 16; Localized in the cytoplasmic and/or outer membrane; Conserved hypothetical protein; lipoprotein 3614023 10975722 zobellia_3123 Zobellia galactanivorans lipoprotein YP_004737541.1 3612644 D 63186 CDS YP_004737542.1 340619089 10975723 3614026..3614844 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 3614844 10975723 zobellia_3124 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004737542.1 3614026 D 63186 CDS YP_004737543.1 340619090 10975724 3614846..3616045 1 NC_015844.1 Mannonate dehydratase, induced By fructuronate, is a Fe2+-requiring enzyme that plays a role in D-glucuronate catabolism; Mannonate dehydratase converts D-mannonate to 2-dehydro-3-deoxy-D-gluconate; Localized in the cytoplasm; High confidence in function and specificity; mannonate dehydratase 3616045 uxuA1 10975724 uxuA1 Zobellia galactanivorans mannonate dehydratase YP_004737543.1 3614846 D 63186 CDS YP_004737544.1 340619091 10978739 complement(3616048..3616476) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3616476 10978739 zobellia_3126 Zobellia galactanivorans hypothetical protein YP_004737544.1 3616048 R 63186 CDS YP_004737545.1 340619092 10975725 complement(3616478..3617149) 1 NC_015844.1 This protein is a permease possibly responsible for zinc uptake; Belongs to the ZIP (zinc transporter proteins) family; Contains seven transmembrane segments; Localized in the cytoplasmic membrane; Specificity unclear; metal ion transporter 3617149 10975725 zobellia_3127 Zobellia galactanivorans metal ion transporter YP_004737545.1 3616478 R 63186 CDS YP_004737546.1 340619093 10975726 3617373..3618527 1 NC_015844.1 Protein of unknown function that contains a N-terminal THUMP (thiouridine synthases, RNA methylases and pseudouridine) domain involved in RNA metabolism with a predicted RNA-binding capacity. Also contains a C-terminal Methylase domain; Belongs to the UPF0020 family; Localized in the cytoplasm; Function unclear; putative RNA methylase 3618527 10975726 zobellia_3128 Zobellia galactanivorans putative RNA methylase YP_004737546.1 3617373 D 63186 CDS YP_004737547.1 340619094 10975727 complement(3618555..3619382) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3619382 10975727 zobellia_3129 Zobellia galactanivorans periplasmic protein YP_004737547.1 3618555 R 63186 CDS YP_004737548.1 340619095 10975728 complement(3619363..3619851) 1 NC_015844.1 Could be a lipoprotein with a signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3619851 10975728 zobellia_3130 Zobellia galactanivorans lipoprotein YP_004737548.1 3619363 R 63186 CDS YP_004737549.1 340619096 10975730 complement(3619856..3621292) 1 NC_015844.1 The RumA protein catalyzes the formation of 5-methyl-uridine at position 1939 (M-5-U1939) in 23S rRNA; Contains two structural domains: an N-terminal TRAM domain predicted to bind RNA and deliver the RNA-modifying enzymatic domain to their targets, and a C-terminal tRNA (Uracil-5-)-methyltransferase domain that displays the typical SAM-dependent methyltransferase fold; Belongs to the RNA M5U methyltransferase family; Localized in the cytoplasm; High confidence in function and specificity; 23S rRNA (uracil-5-)-methyltransferase RumA 3621292 rumA 10975730 rumA Zobellia galactanivorans 23S rRNA (uracil-5-)-methyltransferase RumA YP_004737549.1 3619856 R 63186 CDS YP_004737550.1 340619097 10978558 3621604..3622848 1 NC_015844.1 Ornithine aminotransferase is involved in the Urea cycle and it is responsible for the fourth step in arginine biosynthesis. It catalyzes the transfer of an amino group from ornithine to a 2-oxo acid, yielding glutamic-5-semi-aldehyde and an L-amino acid; Uses the Pyridoxal phosphate as cofactor linked to a conserved lysine residue; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity; ornithine aminotransferase 3622848 rocD 10978558 rocD Zobellia galactanivorans ornithine aminotransferase YP_004737550.1 3621604 D 63186 CDS YP_004737551.1 340619098 10978489 complement(3622902..3623213) 1 NC_015844.1 Contains an N-terminal and a C-terminal transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3623213 10978489 zobellia_3133 Zobellia galactanivorans membrane protein YP_004737551.1 3622902 R 63186 CDS YP_004737552.1 340619099 10975731 complement(3623217..3623546) 1 NC_015844.1 Contains an N-terminal and a C-terminal transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3623546 10975731 zobellia_3134 Zobellia galactanivorans membrane protein YP_004737552.1 3623217 R 63186 CDS YP_004737553.1 340619100 10975732 complement(3623550..3623861) 1 NC_015844.1 Contains two C-terminal transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3623861 10975732 zobellia_3135 Zobellia galactanivorans membrane protein YP_004737553.1 3623550 R 63186 CDS YP_004737554.1 340619101 10975733 3623924..3624469 1 NC_015844.1 Small protein that contain a C-terminal Smr (Small MutS Related) domain; The Smr domain would act as a nicking endonuclease and would interact with the MutS-1 protein; Belongs to the DNA mismatch repair mutS family; Localized in the cytoplasm; Function unclear; Smr protein 3624469 10975733 zobellia_3136 Zobellia galactanivorans Smr protein YP_004737554.1 3623924 D 63186 CDS YP_004737555.1 340619102 10975734 complement(3624466..3625479) 1 NC_015844.1 Liporptein with a signal peptide cleaved between the residues 15 and 16; Localized in the cytoplasmic membrane; Conserved hypothetical protein; lipoprotein 3625479 10975734 zobellia_3137 Zobellia galactanivorans lipoprotein YP_004737555.1 3624466 R 63186 CDS YP_004737556.1 340619103 10975735 3625582..3626730 1 NC_015844.1 Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules as thio-nucleosides in tRNA, thiamine, biotin, lipoate, molybdopterin and Fe-S cluster; Uses the Pyridoxal phosphate as prosthetic group linked to a lysine residue; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity; cysteine desulfurase 3626730 iscS 10975735 iscS Zobellia galactanivorans cysteine desulfurase YP_004737556.1 3625582 D 63186 CDS YP_004737557.1 340619104 10978044 complement(3626762..3627415) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3627415 10978044 zobellia_3139 Zobellia galactanivorans periplasmic protein YP_004737557.1 3626762 R 63186 CDS YP_004737558.1 340619105 10975736 complement(3627427..3629895) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (24-102) and the Plug module (143-223) acting as a channel gate; The signal peptide is cleaved between the residues 23 and 24; High confidence in function and specificity; TonB-dependent Receptor 3629895 10975736 zobellia_3140 Zobellia galactanivorans TonB-dependent Receptor YP_004737558.1 3627427 R 63186 CDS YP_004737559.1 340619106 10975738 complement(3629903..3631594) 1 NC_015844.1 Peptidase family M23 mainly contains endopeptidases that lyze bacterial cell wall peptidoglycans. One catalytic zinc ion is bound per peptidase molecule. The cation ligands occur in the conserved motifs HXXXD and HXH. The first histidine of the second motif is also involved in the catalysis. Features a signal peptide cleaved between the residues 18 and 19. Localized in the periplasm.; Specificity unclear; metallopeptidase 3631594 10975738 zobellia_3141 Zobellia galactanivorans metallopeptidase YP_004737559.1 3629903 R 63186 CDS YP_004737560.1 340619107 10975739 3631788..3632078 1 NC_015844.1 Localized in cytoplasm; hypothetical protein 3632078 10975739 zobellia_3142 Zobellia galactanivorans hypothetical protein YP_004737560.1 3631788 D 63186 CDS YP_004737561.1 340619108 10975740 3632094..3632390 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3632390 10975740 zobellia_3143 Zobellia galactanivorans hypothetical protein YP_004737561.1 3632094 D 63186 CDS YP_004737562.1 340619109 10975741 3632682..3634250 1 NC_015844.1 Possible metal-dependent phosphohydrolase that could act to RNA molecules; Contains an N-terminal transmembrane segment and, in the C-terminal part, one KH domain and an HD domain; The KH domain binds RNA, and can function in RNA recognition; Belongs to the UPF0144 family; Localized in the cytoplasmic membrane; Function unclear; metal-dependent phosphohydrolase 3634250 10975741 zobellia_3144 Zobellia galactanivorans metal-dependent phosphohydrolase YP_004737562.1 3632682 D 63186 CDS YP_004737563.1 340619110 10975742 complement(3634325..3635860) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 19; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Family membership; sulfatase 3635860 10975742 zobellia_3145 Zobellia galactanivorans sulfatase YP_004737563.1 3634325 R 63186 CDS YP_004737564.1 340619111 10975743 complement(3635860..3637494) 1 NC_015844.1 Iduronate-2-sulfatase, called also chondroitinsulfatase is involved in the glycosaminoglycan degradation. It hydrolyzes the 2-sulfate groups from non-reducing-terminal iduronic acid residues in dermatan sulfate, heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 7; Lipoprotein with a signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; High confidence in function and specificity; iduronate-2-sulfatase 3637494 idsA3 10975743 idsA3 Zobellia galactanivorans iduronate-2-sulfatase YP_004737564.1 3635860 R 63186 CDS YP_004737565.1 340619112 10978026 complement(3637536..3639581) 1 NC_015844.1 Conserved protein belonging to the DUF1680 family protein; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3639581 10978026 zobellia_3147 Zobellia galactanivorans periplasmic protein YP_004737565.1 3637536 R 63186 CDS YP_004737566.1 340619113 10975744 complement(3639763..3641733) 1 NC_015844.1 Conserved protein belonging to the DUF1680 family protein; Localized in the cytoplasm; hypothetical protein 3641733 10975744 zobellia_3148 Zobellia galactanivorans hypothetical protein YP_004737566.1 3639763 R 63186 CDS YP_004737567.1 340619114 10975745 complement(3641770..3643350) 1 NC_015844.1 The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; major facilitator family transporter 3643350 10975745 zobellia_3149 Zobellia galactanivorans major facilitator family transporter YP_004737567.1 3641770 R 63186 CDS YP_004737568.1 340619115 10975746 complement(3643390..3645474) 1 NC_015844.1 Protein containing a domain of unknown function DUF1680 predicted to be a possible new family of glycoside hydrolases of unknown specificity; Putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Family membership; membrane protein 3645474 10975746 zobellia_3150 Zobellia galactanivorans membrane protein YP_004737568.1 3643390 R 63186 CDS YP_004737569.1 340619116 10975748 complement(3645790..3647580) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Family membership; sulfatase 3647580 10975748 zobellia_3151 Zobellia galactanivorans sulfatase YP_004737569.1 3645790 R 63186 CDS YP_004737570.1 340619117 10975749 complement(3647622..3649703) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3649703 10975749 zobellia_3152 Zobellia galactanivorans periplasmic protein YP_004737570.1 3647622 R 63186 CDS YP_004737571.1 340619118 10975750 complement(3649765..3650412) 1 NC_015844.1 2-Dehydro-3-deoxy-6-phosphogalactonate aldolase catalyzes the third step of the D-galactonate catabolism: 2-dehydro-3-deoxy-D-galactonate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate. Belongs to the class I aldolase whose catalytic mechanism involves the formation of a Schiff-base intermediate between the substrate and the epsilon-amino group of a lysine residue. Localized in the cytoplasm.; High confidence in function and specificity; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 3650412 dgoA 10975750 dgoA Zobellia galactanivorans 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_004737571.1 3649765 R 63186 CDS YP_004737572.1 340619119 10977736 complement(3650402..3651355) 1 NC_015844.1 2-Dehydro-3-deoxygalactonokinase catalyzes the second step in D-galactonate degradation: ATP + 2-dehydro-3-deoxy-D-galactonate = ADP + 2-dehydro-3-deoxy-D-galactonate 6-phosphate. Localized in the cytoplasm.; High confidence in function and specificity; 2-dehydro-3-deoxygalactonokinase 3651355 dgoK 10977736 dgoK Zobellia galactanivorans 2-dehydro-3-deoxygalactonokinase YP_004737572.1 3650402 R 63186 CDS YP_004737573.1 340619120 10977740 complement(3651352..3652803) 1 NC_015844.1 Lactaldehyde dehydrogenase catalyze the NAD-dependent oxidation of lactaldehyde into lactate. This protein is a tetramer. AldA is involved in the catabolism of L-fucose and L-rhamnose and is induced by these sugars. In aerobic condition, the lactaldehyde is produced by the cleavage of L-fucose or L-rhamnose; Belongs to the aldehyde dehydrogenase fold family; Localized in the cytoplasm; High confidence in function and specificity; Lactaldehyde dehydrogenase 3652803 aldA 10977740 aldA Zobellia galactanivorans Lactaldehyde dehydrogenase YP_004737573.1 3651352 R 63186 CDS YP_004737574.1 340619121 10977490 complement(3652778..3653944) 1 NC_015844.1 Galactonate dehydratase catalyzes the first step of the D-galactonate catabolism converting the D-galactonate to 2-dehydro-3-deoxy-D-galactonate; Contains a N-terminal Enolase-like fold and a C-terminal TIM alpha/beta barrel fold; Belongs to the Mandelate racemase/muconate lactonizing enzyme family; Localized in the cytoplasm; High confidence in function and specificity; galactonate dehydratase 3653944 dgoD 10977490 dgoD Zobellia galactanivorans galactonate dehydratase YP_004737574.1 3652778 R 63186 CDS YP_004737575.1 340619122 10977737 complement(3653980..3654987) 1 NC_015844.1 L-rhamnose/proton symporter is involved in the uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell. Can also transport L-mannose and L-xylose, but at reduced rates. Contains ten transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; L-rhamnose/proton symporter 3654987 rhaT1 10977737 rhaT1 Zobellia galactanivorans L-rhamnose/proton symporter YP_004737575.1 3653980 R 63186 CDS YP_004737576.1 340619123 10978454 complement(3655123..3656424) 1 NC_015844.1 GntT is part of the gluconate utilization system Gnt-I. It is a permease responsible for high-affinity intake of gluconate; Contains twelve transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; high-affinity gluconate transporter 3656424 gntT3 10978454 gntT3 Zobellia galactanivorans high-affinity gluconate transporter YP_004737576.1 3655123 R 63186 CDS YP_004737577.1 340619124 10977945 complement(3656545..3657429) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 3657429 10977945 zobellia_3159 Zobellia galactanivorans AraC family transcriptional regulator YP_004737577.1 3656545 R 63186 CDS YP_004737578.1 340619125 10975751 complement(3657707..3658861) 1 NC_015844.1 L-lactate dehydrogenase is involved in L-lactate degradation converting the L-lactate to pyruvate; Uses flavin mononucleotide (FMN) as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity; l-lactate dehydrogenase 3658861 lldD1 10975751 lldD1 Zobellia galactanivorans l-lactate dehydrogenase YP_004737578.1 3657707 R 63186 CDS YP_004737579.1 340619126 10978095 complement(3658871..3660298) 1 NC_015844.1 Carbohydrate kinase belonging to the FGGY family. Its exact specificity is unknown; Localized in the cytoplasm; Specificity unclear; carbohydrate kinase 3660298 10978095 zobellia_3161 Zobellia galactanivorans carbohydrate kinase YP_004737579.1 3658871 R 63186 CDS YP_004737580.1 340619127 10975753 complement(3660282..3662387) 1 NC_015844.1 Contains an hypothetical N-terminal aldolase II domain and a C-terminal domain belonging to the short chain dehydrogenase family; Localized in the cytoplasm; Specificity unclear; oxydoreductase 3662387 10975753 zobellia_3162 Zobellia galactanivorans oxydoreductase YP_004737580.1 3660282 R 63186 CDS YP_004737581.1 340619128 10975754 3662580..3663626 1 NC_015844.1 Transcriptional regulator involved in the repression and/or the positive regulation of genes encoding for enzymes; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcriptional regulators, involved in the binding of the protein to the operator sequences in the DNA. At the C-terminus there is an effector- binding/oligomerisation domain; Localized in the cytoplasm; Family membership; GntR family transcriptional regulator 3663626 10975754 zobellia_3163 Zobellia galactanivorans GntR family transcriptional regulator YP_004737581.1 3662580 D 63186 CDS YP_004737582.1 340619129 10975755 3663846..3666536 1 NC_015844.1 Large conserved protein containing a C-terminal cytochrome C. Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Conserved hypothetical protein; cytochrome c-containing lipoprotein 3666536 10975755 zobellia_3164 Zobellia galactanivorans cytochrome c-containing lipoprotein YP_004737582.1 3663846 D 63186 CDS YP_004737583.1 340619130 10975756 3666578..3667444 1 NC_015844.1 Conserved protein belonging to the DUF1080 family; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3667444 10975756 zobellia_3165 Zobellia galactanivorans membrane protein YP_004737583.1 3666578 D 63186 CDS YP_004737584.1 340619131 10975757 3667471..3668541 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3668541 10975757 zobellia_3166 Zobellia galactanivorans hypothetical protein YP_004737584.1 3667471 D 63186 CDS YP_004737585.1 340619132 10975758 3668559..3669770 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3669770 10975758 zobellia_3167 Zobellia galactanivorans hypothetical protein YP_004737585.1 3668559 D 63186 CDS YP_004737586.1 340619133 10975759 3669865..3670893 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3670893 10975759 zobellia_3168 Zobellia galactanivorans hypothetical protein YP_004737586.1 3669865 D 63186 CDS YP_004737587.1 340619134 10975760 3670914..3671723 1 NC_015844.1 The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine; The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Localized in the cytoplasm; Function unclear; alpha/beta hydrolase-fold protein 3671723 10975760 zobellia_3169 Zobellia galactanivorans alpha/beta hydrolase-fold protein YP_004737587.1 3670914 D 63186 CDS YP_004737588.1 340619135 10975761 3671809..3672621 1 NC_015844.1 Conserved protein belonging to the Xylose isomerase-like TIM barrel family; Localized in the cytoplasm; Family membership; xylose isomerase-like TIM barrel protein 3672621 10975761 zobellia_3170 Zobellia galactanivorans xylose isomerase-like TIM barrel protein YP_004737588.1 3671809 D 63186 CDS YP_004737589.1 340619136 10975763 3672656..3673807 1 NC_015844.1 NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family; Adopts a Rossmann fold; Localized in the cytoplasm; Specificity unclear; NAD(P)-dependent oxidoreductase 3673807 10975763 zobellia_3171 Zobellia galactanivorans NAD(P)-dependent oxidoreductase YP_004737589.1 3672656 D 63186 CDS YP_004737590.1 340619137 10975764 complement(3673904..3674989) 1 NC_015844.1 GDP-L-fucose synthetase is involved in EPS biosynthesis. It catalyzes the two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction; Forms a homodimer; Localized in the cytoplasm.; High confidence in function and specificity; GDP-L-fucose synthetase 3674989 fclA 10975764 fclA Zobellia galactanivorans GDP-L-fucose synthetase YP_004737590.1 3673904 R 63186 CDS YP_004737591.1 340619138 10977820 complement(3674991..3676103) 1 NC_015844.1 GDP-mannose 4,6-dehydratase converts GDP-mannose to GDP-4-dehydro-6-deoxy-D-mannose, the first of three steps for the conversion of GDP-mannose to GDP-fucose. GDP-L-fucose acts as a precursor of surface polysaccharidic antigens; Belongs to the Rossmann fold Superfamily, NAD-dependent epimerase/dehydratase family; Localized in the cytoplasm; High confidence in function and specificity; GDP-mannose 4,6-dehydratase 3676103 gmdA 10977820 gmdA Zobellia galactanivorans GDP-mannose 4,6-dehydratase YP_004737591.1 3674991 R 63186 CDS YP_004737592.1 340619139 10977937 complement(3676312..3677688) 1 NC_015844.1 NAD(P)-dependent dehydrogenase belonging to the Rossmann fold family; Contains a twin-arginine translocation signal peptide cleaved between the residues 30 and 31; Localized in the periplasmic space; Specificity unclear; NAD(P)-dependent dehydrogenase 3677688 10977937 zobellia_3174 Zobellia galactanivorans NAD(P)-dependent dehydrogenase YP_004737592.1 3676312 R 63186 CDS YP_004737593.1 340619140 10975765 3677809..3679197 1 NC_015844.1 Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; High confidence in function and specificity; sialate O-acetylesterase 3679197 siaE1 10975765 siaE1 Zobellia galactanivorans sialate O-acetylesterase YP_004737593.1 3677809 D 63186 CDS YP_004737594.1 340619141 10978594 3679269..3681380 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 22 and 23; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 3681380 10978594 zobellia_3176 Zobellia galactanivorans membrane protein YP_004737594.1 3679269 D 63186 CDS YP_004737595.1 340619142 10975766 3681480..3683198 1 NC_015844.1 Oxidoreductase that binds the FAD as prosthetic group to the FAD ADP-binding domain located in the N-terminal section of the protein; Belongs to the GMC (glucose-methanol-choline) oxidoreductase family; Localized in the cytoplasm; Specificity unclear; FAD-dependent oxidoreductase 3683198 10975766 zobellia_3177 Zobellia galactanivorans FAD-dependent oxidoreductase YP_004737595.1 3681480 D 63186 CDS YP_004737596.1 340619143 10975767 3683205..3683924 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 22 and 23; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 3683924 10975767 zobellia_3178 Zobellia galactanivorans membrane protein YP_004737596.1 3683205 D 63186 CDS YP_004737597.1 340619144 10975768 3684003..3684824 1 NC_015844.1 Conserved protein belonging to the Xylose isomerase-like TIM barrel family; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Family membership; xylose isomerase-like TIM barrel protein 3684824 10975768 zobellia_3179 Zobellia galactanivorans xylose isomerase-like TIM barrel protein YP_004737597.1 3684003 D 63186 CDS YP_004737598.1 340619145 10975769 3685021..3686877 1 NC_015844.1 Protein that could be involved in the carbohydrates metabolism; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3686877 10975769 zobellia_3180 Zobellia galactanivorans lipoprotein YP_004737598.1 3685021 D 63186 CDS YP_004737599.1 340619146 10975771 3686964..3687692 1 NC_015844.1 D-Ala-D-Ala dipeptidase hydrolyzes the D-Ala-D-Ala dipeptide, reducing its cellular pool so that only the resistant D-Ala-D-lactate dipeptide is incorporated into the peptidoglycan. Belongs to the family 15 of the metallopeptidases. The catalytic zinc is bound by conserved His, Asp and His residues. Features a signal peptide cleaved between the residues 18 and 19. Localized in the periplasm.; High confidence in function and specificity; D-Ala-D-Ala dipeptidase 5 3687692 ddpX 10975771 ddpX Zobellia galactanivorans D-Ala-D-Ala dipeptidase 5 YP_004737599.1 3686964 D 63186 CDS YP_004737600.1 340619147 10977727 3687707..3688621 1 NC_015844.1 Pectin acetylesterase hydrolyzes acetyl groups in pectins, releasing acetates. This enzyme belongs to the family 10 of the carbohydrate esterases. Features a signal peptide cleaved between residues 18 and 19. Localized in the periplasm.; High confidence in function and specificity; pectin acetylesterase, family CE10 3688621 paeX 10977727 paeX Zobellia galactanivorans pectin acetylesterase, family CE10 YP_004737600.1 3687707 D 63186 CDS YP_004737601.1 340619148 10978295 complement(3688679..3690256) 1 NC_015844.1 Sheath polysaccharide lyase catalyzes the eliminative cleavage of bacterial polysaccharides containing uronic acids. Probably adopts a parallel beta-helix fold; Signal peptide cleaved between residues 21 and 22; Likely localized in the outer membrane; High confidence in function and specificity; sheath polysaccharide lyase 3690256 dssA 10978295 dssA Zobellia galactanivorans sheath polysaccharide lyase YP_004737601.1 3688679 R 63186 CDS YP_004737602.1 340619149 10974050 3690680..3690916 1 NC_015844.1 Hypothetical protein; hypothetical protein 3690916 10974050 zobellia_3185 Zobellia galactanivorans hypothetical protein YP_004737602.1 3690680 D 63186 CDS YP_004737603.1 340619150 10975772 3690898..3691101 1 NC_015844.1 Hypothetical protein; hypothetical protein 3691101 10975772 zobellia_3186 Zobellia galactanivorans hypothetical protein YP_004737603.1 3690898 D 63186 CDS YP_004737604.1 340619151 10975773 3691422..3692534 1 NC_015844.1 Integrase are site-specific tyrosine recombinases that act by catalyzing the cutting and rejoining of the recombining DNA molecules utilizing a catalytic tyrosine for the strand cleavage. These integrases includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and a secondary target, attC, present on various mobile gene cassettes; Contains a C-terminal Phage integrase domain; Belongs to the \\phage\\ integrase family, integron-related integrase subfamily; Localized in the cytoplasm; Family membership; integron-related integrase 3692534 10975773 zobellia_3187 Zobellia galactanivorans integron-related integrase YP_004737604.1 3691422 D 63186 CDS YP_004737605.1 340619152 10975774 3692877..3693194 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3693194 10975774 zobellia_3188 Zobellia galactanivorans lipoprotein YP_004737605.1 3692877 D 63186 CDS YP_004737606.1 340619153 10975775 3693247..3695433 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (23-99) and the Plug module (124-228) acting as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 3695433 10975775 zobellia_3189 Zobellia galactanivorans TonB-dependent Receptor YP_004737606.1 3693247 D 63186 CDS YP_004737607.1 340619154 10975776 3695436..3695852 1 NC_015844.1 Transcriptional regulator featuring a helix-turn-helix DNA binding motif belonging to the Fur family. This family includes metal ion uptake regulator, that bind to the operator DNA and controls transcription of metal ion-responsive genes. Localized in the cytoplasm.; Specificity unclear; Fur-type transcriptional regulator 3695852 10975776 zobellia_3190 Zobellia galactanivorans Fur-type transcriptional regulator YP_004737607.1 3695436 D 63186 CDS YP_004737608.1 340619155 10975778 3695906..3696490 1 NC_015844.1 Could belong to the isoprenylcysteine carboxyl methyltransferase (ICMT) family; Contains four transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 3696490 10975778 zobellia_3191 Zobellia galactanivorans membrane protein YP_004737608.1 3695906 D 63186 CDS YP_004737609.1 340619156 10975779 3696863..3697354 1 NC_015844.1 Contains three transmembrane helices. Localized in the cytoplasmic membrane.; Hypothetical protein; hypothetical protein 3697354 10975779 zobellia_3192 Zobellia galactanivorans hypothetical protein YP_004737609.1 3696863 D 63186 CDS YP_004737610.1 340619157 10975780 3697547..3698398 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 3698398 10975780 zobellia_3193 Zobellia galactanivorans hypothetical protein YP_004737610.1 3697547 D 63186 CDS YP_004737611.1 340619158 10975781 complement(3698526..3699497) 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 20 of transposases; Localized in the cytoplasm.; Family membership; transposase, family 20 3699497 10975781 zobellia_3194 Zobellia galactanivorans transposase, family 20 YP_004737611.1 3698526 R 63186 CDS YP_004737612.1 340619159 10975782 complement(3699784..3701364) 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to family 11 of transposases; Localized in the cytoplasm; Family membership; transposase, family 11 3701364 10975782 zobellia_3195 Zobellia galactanivorans transposase, family 11 YP_004737612.1 3699784 R 63186 CDS YP_004737613.1 340619160 10975783 3701572..3702219 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 3702219 10975783 zobellia_3196 Zobellia galactanivorans hypothetical protein YP_004737613.1 3701572 D 63186 CDS YP_004737614.1 340619161 10975784 3702235..3702834 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 3702834 10975784 zobellia_3197 Zobellia galactanivorans hypothetical protein YP_004737614.1 3702235 D 63186 CDS YP_004737615.1 340619162 10975785 complement(3702966..3703187) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3703187 10975785 zobellia_3198 Zobellia galactanivorans hypothetical protein YP_004737615.1 3702966 R 63186 CDS YP_004737616.1 340619163 10975786 3703201..3703593 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 3703593 10975786 zobellia_3199 Zobellia galactanivorans hypothetical protein YP_004737616.1 3703201 D 63186 CDS YP_004737617.1 340619164 10975787 3703765..3704109 1 NC_015844.1 Conserved protein containing a tetratrico peptide repeat (TPR). TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Localized in the cytoplasm; hypothetical protein 3704109 10975787 zobellia_3200 Zobellia galactanivorans hypothetical protein YP_004737617.1 3703765 D 63186 CDS YP_004737618.1 340619165 10975788 3704366..3704923 1 NC_015844.1 The Crp/Fnr-type transcriptional regulators complexe with cyclic AMP and bind to operator sites near the promoter with a C-terminal HTH domain to regulate the transcription of several catabolite-sensitive operons; They predominantly act as transcription activators, but can also be important repressors, and respond to diverse intracellular and exogenous signals; Localized in the cytoplasm; Family membership; Crp/Fnr-type transcriptional regulator 3704923 10975788 zobellia_3201 Zobellia galactanivorans Crp/Fnr-type transcriptional regulator YP_004737618.1 3704366 D 63186 CDS YP_004737619.1 340619166 10975789 3705006..3705815 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Family membership; short-chain dehydrogenase/reductase 3705815 10975789 zobellia_3202 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004737619.1 3705006 D 63186 CDS YP_004737620.1 340619167 10975790 3706031..3706378 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 3706378 10975790 zobellia_3203 Zobellia galactanivorans hypothetical protein YP_004737620.1 3706031 D 63186 CDS YP_004737621.1 340619168 10975791 complement(3706618..3708192) 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to family 11 of transposases; Localized in the cytoplasm; Family membership; transposase, family 11 3708192 10975791 zobellia_3204 Zobellia galactanivorans transposase, family 11 YP_004737621.1 3706618 R 63186 CDS YP_004737622.1 340619169 10975792 3708296..3708955 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3708955 10975792 zobellia_3205 Zobellia galactanivorans hypothetical protein YP_004737622.1 3708296 D 63186 CDS YP_004737623.1 340619170 10975793 3709271..3710176 1 NC_015844.1 Protein containing C-terminal leucine-rich repeats. Leucine-rich repeats consist of 2-45 motifs of 20-30 amino acids in length that generally folds into a horseshoe shape; Localized in the cytoplasm; hypothetical protein 3710176 10975793 zobellia_3206 Zobellia galactanivorans hypothetical protein YP_004737623.1 3709271 D 63186 CDS YP_004737624.1 340619171 10975794 3710532..3710963 1 NC_015844.1 Protein of unknown function belonging to the glyocylase I family; Localized in the cytoplasm; Family membership; glyoxalase family protein 3710963 10975794 zobellia_3207 Zobellia galactanivorans glyoxalase family protein YP_004737624.1 3710532 D 63186 CDS YP_004737625.1 340619172 10975795 complement(3711225..3712451) 1 NC_015844.1 This protein is the membrane subunit of a oxidoreductase complex of unknown specificity; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; oxidoreductase complex, membrane subunit 3712451 10975795 zobellia_3208 Zobellia galactanivorans oxidoreductase complex, membrane subunit YP_004737625.1 3711225 R 63186 CDS YP_004737626.1 340619173 10975796 complement(3712533..3713663) 1 NC_015844.1 This protein is the iron-sulfur subunit of a oxidoreductase of unknown specificity. It binds a 4Fe-4S cluster. This subunit interact with a membrane subunit; Localized in the cytoplasmic membrane; Specificity unclear; oxidoreductase complex, iron-sulfur subunit 3713663 10975796 zobellia_3209 Zobellia galactanivorans oxidoreductase complex, iron-sulfur subunit YP_004737626.1 3712533 R 63186 CDS YP_004737627.1 340619174 10975797 complement(3713674..3714303) 1 NC_015844.1 Protein that contains four consensus sequence Cys-x-x-Cys-His, where the histidine residue is one of the two axial ligands of the heme iron; Belongs to the Multiheme C-type cytochrome family; Putative lipoprotein signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; Function unclear; diheme cytochrome c 3714303 10975797 zobellia_3210 Zobellia galactanivorans diheme cytochrome c YP_004737627.1 3713674 R 63186 CDS YP_004737628.1 340619175 10975799 complement(3714293..3715015) 1 NC_015844.1 The diheme cytochrome c napB is the small subunit of the periplasmic nitrate reductase (NAP). NapAB complex receives electrons from the membrane-anchored tetraheme napC protein, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism. Features four consensus sequence Cys-x-x-Cys-His, where the histidine residue is one of the two axial ligands of the heme iron. Binds two hemes. Features an uncleaved signal peptide. Localized in the cytoplasmic membrane.; High confidence in function and specificity; diheme cytochrome c NapB 3715015 napB 10975799 napB Zobellia galactanivorans diheme cytochrome c NapB YP_004737628.1 3714293 R 63186 CDS YP_004737629.1 340619176 10978237 complement(3715019..3717346) 1 NC_015844.1 Catalytic subunit of the periplasmic nitrate reductase involved in the denitrification processes (nitrate assimilation by anaerobic respiration) reducing nitrate to nitrite. Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein napC, thus allowing electron flow between membrane and periplasm; Uses two molybdopterin guanine dinucleotide groups per subunit and 1 4Fe-4S cluster as cofactors; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family; Signal peptide cleaved between the residues 34 and 35; Exported by the twin arginine translocation pathway; High confidence in function and specificity; periplasmic nitrate reductase, catalytic subunit 3717346 napA 10978237 napA Zobellia galactanivorans periplasmic nitrate reductase, catalytic subunit YP_004737629.1 3715019 R 63186 CDS YP_004737630.1 340619177 10978236 complement(3717358..3717591) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3717591 10978236 zobellia_3213 Zobellia galactanivorans hypothetical protein YP_004737630.1 3717358 R 63186 CDS YP_004737631.1 340619178 10975800 3717908..3719089 1 NC_015844.1 Enzyme Involved in the biosynthesis of molybdopterin, necessary for molybdo-enzymes. MoeA, together with MoaB, is responsible for the metal incorporation into molybdopterin, the third step in molybdenum cofactor biosynthesis; Binds one magnesium ion; Localized in the cytoplasm; High confidence in function and specificity; molybdopterin biosynthesis protein 3719089 moeA1 10975800 moeA1 Zobellia galactanivorans molybdopterin biosynthesis protein YP_004737631.1 3717908 D 63186 CDS YP_004737632.1 340619179 10978171 3719099..3719440 1 NC_015844.1 The ModE-Mo complex acts as a repressor of genes involved in the transport of molybdate into the cell. Upon binding molybdate, the conformation of the protein changes, promoting dimerization of ModE-Mo. The protein dimer is then competent to bind a DNA region; This protein consists of a LysR-type HTH domain only (the C-terminal domain is absent); Localized in the cytoplasm; High confidence in function and specificity; LysR family transcriptional regulator 3719440 modE 10978171 modE Zobellia galactanivorans LysR family transcriptional regulator YP_004737632.1 3719099 D 63186 CDS YP_004737633.1 340619180 10978170 3719535..3719975 1 NC_015844.1 Molybdopterin synthase converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group responsible for molybdenum ligation; The enzyme is a heterodimer of 2 small (moaD) subunits and 2 large (moaE) subunits; Localized in the cytoplasm; Hypothetical protein; molybdopterin synthase, large subunit 3719975 moaE2 10978170 moaE2 Zobellia galactanivorans molybdopterin synthase, large subunit YP_004737633.1 3719535 D 63186 CDS YP_004737634.1 340619181 10978166 complement(3720254..3721546) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3721546 10978166 zobellia_3217 Zobellia galactanivorans periplasmic protein YP_004737634.1 3720254 R 63186 CDS YP_004737635.1 340619182 10975801 complement(3721632..3722081) 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 3722081 10975801 zobellia_3218 Zobellia galactanivorans hypothetical protein YP_004737635.1 3721632 R 63186 CDS YP_004737636.1 340619183 10975802 3722580..3724880 1 NC_015844.1 Topoisomerase III can be purified as a potent concatenase, but its role in DNA metabolism is still unclear; Belongs to the prokaryotic type I topoisomerase family; The type I topoisomerases catalyze the interconversion of DNA topoisomers by transient ATP-independent breakage of single-stranded DNA and the subsequent rejoining of the strands via a protein-DNA link where the hydroxyl group of a tyrosine residue is joined to a 5'-phosphate on DNA; Localized in the cytoplasm; High confidence in function and specificity; DNA topoisomerase III 3724880 topB 10975802 topB Zobellia galactanivorans DNA topoisomerase III YP_004737636.1 3722580 D 63186 CDS YP_004737637.1 340619184 10978674 complement(3725129..3725887) 1 NC_015844.1 Transcriptional regulator belonging to the LuxR family. Features a C-terminal helix-turn-helix DNA binding motif. Localized in the cytoplasm.; Specificity unclear; LuxR-type transcriptional regulator 3725887 10978674 zobellia_3220 Zobellia galactanivorans LuxR-type transcriptional regulator YP_004737637.1 3725129 R 63186 CDS YP_004737638.1 340619185 10975803 3726189..3728561 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (22-108) and the Plug module (122-217) acting as a channel gate; The signal peptide is putatively cleaved between the residues 25 and 26; Family membership; TonB-dependent Receptor 3728561 10975803 zobellia_3221 Zobellia galactanivorans TonB-dependent Receptor YP_004737638.1 3726189 D 63186 CDS YP_004737639.1 340619186 10975804 complement(3728686..3730317) 1 NC_015844.1 Conserved protein containing a N-terminal type-III fibronectin (FN3) domains. Structures of individual FN3 domains have revealed a conserved beta sandwich fold also found in bacterial glycosyde hydrolases and other proteins; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; fibronectin type-III repeat-containing protein 3730317 10975804 zobellia_3222 Zobellia galactanivorans fibronectin type-III repeat-containing protein YP_004737639.1 3728686 R 63186 CDS YP_004737640.1 340619187 10975805 3730380..3730559 1 NC_015844.1 Hypothetical protein; hypothetical protein 3730559 10975805 zobellia_3223 Zobellia galactanivorans hypothetical protein YP_004737640.1 3730380 D 63186 CDS YP_004737641.1 340619188 10975806 complement(3730543..3731214) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Hypothetical protein; hypothetical protein 3731214 10975806 zobellia_3224 Zobellia galactanivorans hypothetical protein YP_004737641.1 3730543 R 63186 CDS YP_004737642.1 340619189 10975807 complement(3731253..3731987) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Hypothetical protein; hypothetical protein 3731987 10975807 zobellia_3225 Zobellia galactanivorans hypothetical protein YP_004737642.1 3731253 R 63186 CDS YP_004737643.1 340619190 10975808 complement(3732038..3732841) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Hypothetical protein; hypothetical protein 3732841 10975808 zobellia_3226 Zobellia galactanivorans hypothetical protein YP_004737643.1 3732038 R 63186 CDS YP_004737644.1 340619191 10975809 complement(3733156..3734655) 1 NC_015844.1 Tyrosine decarboxylase catalyzes the reaction : L-tyrosine = tyramine + CO2. This enzyme covalently binds the cofactor pyridoxal-phosphate (PLP) on a conserved lysine. Localized in the cytoplasm.; High confidence in function and specificity; tyrosine decarboxylase 3734655 tyrDC 10975809 tyrDC Zobellia galactanivorans tyrosine decarboxylase YP_004737644.1 3733156 R 63186 CDS YP_004737645.1 340619192 10978718 complement(3734870..3735418) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3735418 10978718 zobellia_3228 Zobellia galactanivorans periplasmic protein YP_004737645.1 3734870 R 63186 CDS YP_004737646.1 340619193 10975810 complement(3735455..3736150) 1 NC_015844.1 Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3736150 10975810 zobellia_3229 Zobellia galactanivorans membrane protein YP_004737646.1 3735455 R 63186 CDS YP_004737647.1 340619194 10975811 complement(3736205..3736780) 1 NC_015844.1 The Crp/Fnr-type transcriptional regulators complexe with cyclic AMP and bind to operator sites near the promoter with a C-terminal HTH domain to regulate the transcription of several catabolite-sensitive operons; They predominantly act as transcription activators, but can also be important repressors, and respond to diverse intracellular and exogenous signals; Localized in the cytoplasm; Specificity unclear; Crp/Fnr-type transcriptional regulator 3736780 10975811 zobellia_3230 Zobellia galactanivorans Crp/Fnr-type transcriptional regulator YP_004737647.1 3736205 R 63186 CDS YP_004737648.1 340619195 10975813 complement(3736777..3736878) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3736878 10975813 zobellia_3231 Zobellia galactanivorans hypothetical protein YP_004737648.1 3736777 R 63186 CDS YP_004737649.1 340619196 10975814 complement(3737135..3737755) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3737755 10975814 zobellia_3232 Zobellia galactanivorans hypothetical protein YP_004737649.1 3737135 R 63186 CDS YP_004737650.1 340619197 10975815 3737805..3738086 1 NC_015844.1 Hypothetical protein; hypothetical protein 3738086 10975815 zobellia_3233 Zobellia galactanivorans hypothetical protein YP_004737650.1 3737805 D 63186 CDS YP_004737651.1 340619198 10975816 complement(3738604..3739068) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3739068 10975816 zobellia_3234 Zobellia galactanivorans lipoprotein YP_004737651.1 3738604 R 63186 CDS YP_004737652.1 340619199 10975817 3739117..3739323 1 NC_015844.1 Hypothetical protein; hypothetical protein 3739323 10975817 zobellia_3235 Zobellia galactanivorans hypothetical protein YP_004737652.1 3739117 D 63186 CDS YP_004737653.1 340619200 10975818 complement(3739891..3740301) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3740301 10975818 zobellia_3236 Zobellia galactanivorans hypothetical protein YP_004737653.1 3739891 R 63186 CDS YP_004737654.1 340619201 10975819 complement(3740319..3741722) 1 NC_015844.1 PLP-dependent decarboxylase catalyzes the decarboxylation of various substrates. Its exact specificity is not known. Uses pyridoxal-phosphate (PLP) as prosthetic group; Localized in the cytoplasm; Specificity unclear; PLP-dependent decarboxylase 3741722 10975819 zobellia_3237 Zobellia galactanivorans PLP-dependent decarboxylase YP_004737654.1 3740319 R 63186 CDS YP_004737655.1 340619202 10975820 3741850..3741987 1 NC_015844.1 Hypothetical protein; hypothetical protein 3741987 10975820 zobellia_3238 Zobellia galactanivorans hypothetical protein YP_004737655.1 3741850 D 63186 CDS YP_004737656.1 340619203 10975821 3742100..3742555 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3742555 10975821 zobellia_3239 Zobellia galactanivorans hypothetical protein YP_004737656.1 3742100 D 63186 CDS YP_004737657.1 340619204 10975822 3742545..3743108 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3743108 10975822 zobellia_3240 Zobellia galactanivorans hypothetical protein YP_004737657.1 3742545 D 63186 CDS YP_004737658.1 340619205 10975824 complement(3743243..3744067) 1 NC_015844.1 Contains nine transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3744067 10975824 zobellia_3241 Zobellia galactanivorans membrane protein YP_004737658.1 3743243 R 63186 CDS YP_004737659.1 340619206 10975825 complement(3744170..3744376) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3744376 10975825 zobellia_3242 Zobellia galactanivorans hypothetical protein YP_004737659.1 3744170 R 63186 CDS YP_004737660.1 340619207 10975826 complement(3744422..3746848) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (24-111) and the Plug module (125-224) acting as a channel gate; The signal peptide is cleaved between the residues 21 and 22; Family membership; TonB-dependent Receptor 3746848 10975826 zobellia_3243 Zobellia galactanivorans TonB-dependent Receptor YP_004737660.1 3744422 R 63186 CDS YP_004737661.1 340619208 10975827 3746866..3746991 1 NC_015844.1 Hypothetical protein; hypothetical protein 3746991 10975827 zobellia_3244 Zobellia galactanivorans hypothetical protein YP_004737661.1 3746866 D 63186 CDS YP_004737662.1 340619209 10975828 3747045..3748208 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains four N-terminal transmembrane segments; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 3748208 10975828 zobellia_3245 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004737662.1 3747045 D 63186 CDS YP_004737663.1 340619210 10975829 3748189..3748959 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, that acts as transcriptional regulator; Family membership; two-component system-response regulator 3748959 10975829 zobellia_3246 Zobellia galactanivorans two-component system-response regulator YP_004737663.1 3748189 D 63186 CDS YP_004737664.1 340619211 10975830 complement(3748992..3749855) 1 NC_015844.1 Contains two acetyltransferase domains; The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 3749855 10975830 zobellia_3247 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004737664.1 3748992 R 63186 CDS YP_004737665.1 340619212 10975831 complement(3749857..3750072) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3750072 10975831 zobellia_3248 Zobellia galactanivorans hypothetical protein YP_004737665.1 3749857 R 63186 CDS YP_004737666.1 340619213 10975832 complement(3750171..3751925) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3751925 10975832 zobellia_3249 Zobellia galactanivorans hypothetical protein YP_004737666.1 3750171 R 63186 CDS YP_004737667.1 340619214 10975833 complement(3752457..3753452) 1 NC_015844.1 Bifunctional enzyme involved in the nicotinate and nicotinamide metabolism possessing both NMN (nicotinamide mononucleotide) adenylytransferase (NMNAT) and Ribosylnicotinamide kinase (RNK) activities. NMNAT is an indispensable activity in the biosynthesis of NAD(+) and NADP(+) synthesizing NAD via the salvage pathway. RNK converts the N-ribosylnicotinamide to nicotinamide ribonucleotide; Localized in the cytoplasm. However, this bifunctional enzyme would loosely associate with the membrane through its interaction with the membrane-bound PnuC; High confidence in function and specificity; Nicotinamide-nucleotide adenylyltransferase / ribosylnicotinamide kinase 3753452 nadR 10975833 nadR Zobellia galactanivorans Nicotinamide-nucleotide adenylyltransferase / ribosylnicotinamide kinase YP_004737667.1 3752457 R 63186 CDS YP_004737668.1 340619215 10978223 complement(3753445..3754074) 1 NC_015844.1 PnuC is the membrane protein responsible for nicotinamide mononucleotide transport; Contains seven transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; Nicotinamide mononucleotide transporter 3754074 pnuC2 10978223 pnuC2 Zobellia galactanivorans Nicotinamide mononucleotide transporter YP_004737668.1 3753445 R 63186 CDS YP_004737669.1 340619216 10978359 complement(3754074..3756071) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Does not contain of carboxypeptidase regulatory domain. The Plug module (41-152) acts as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 3756071 10978359 zobellia_3252 Zobellia galactanivorans TonB-dependent Receptor YP_004737669.1 3754074 R 63186 CDS YP_004737670.1 340619217 10975835 complement(3756094..3756663) 1 NC_015844.1 Conserved protein containing two tetratrico peptide repeats (TPRs). TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Localized in the cytoplasm; hypothetical protein 3756663 10975835 zobellia_3253 Zobellia galactanivorans hypothetical protein YP_004737670.1 3756094 R 63186 CDS YP_004737671.1 340619218 10975836 complement(3756772..3757263) 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 3757263 10975836 zobellia_3254 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004737671.1 3756772 R 63186 CDS YP_004737672.1 340619219 10975837 complement(3757569..3758231) 1 NC_015844.1 Conserved lipoprotein that consists of a SCO1/SenC domain; Belongs to the SCO2/SenC family; Signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Family membership; lipoprotein 3758231 10975837 zobellia_3255 Zobellia galactanivorans lipoprotein YP_004737672.1 3757569 R 63186 CDS YP_004737673.1 340619220 10975838 complement(3758218..3758778) 1 NC_015844.1 Conserved lipoprotein that contains three repeats of twenty aminoacids putatively The MORN (membrane occupation and recognition nexus) repeats would contribute to the plasma membrane binding, possibly by interacting with phospholipids; Signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3758778 10975838 zobellia_3256 Zobellia galactanivorans lipoprotein YP_004737673.1 3758218 R 63186 CDS YP_004737674.1 340619221 10975839 complement(3758783..3759466) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3759466 10975839 zobellia_3257 Zobellia galactanivorans hypothetical protein YP_004737674.1 3758783 R 63186 CDS YP_004737675.1 340619222 10975840 complement(3759585..3760928) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 29; Lipoprotein with a signal peptide cleaved between the residues 18 and 19; localized in the outer membrane; Family membership; sulfatase 3760928 10975840 zobellia_3258 Zobellia galactanivorans sulfatase YP_004737675.1 3759585 R 63186 CDS YP_004737676.1 340619223 10975841 complement(3761473..3761931) 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 3761931 10975841 zobellia_3259 Zobellia galactanivorans hypothetical protein YP_004737676.1 3761473 R 63186 CDS YP_004737677.1 340619224 10975842 3762323..3762565 1 NC_015844.1 Hypothetical protein; hypothetical protein 3762565 10975842 zobellia_3260 Zobellia galactanivorans hypothetical protein YP_004737677.1 3762323 D 63186 CDS YP_004737678.1 340619225 10975844 complement(3762686..3762835) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3762835 10975844 zobellia_3261 Zobellia galactanivorans hypothetical protein YP_004737678.1 3762686 R 63186 CDS YP_004737679.1 340619226 10975845 complement(3763574..3764242) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3764242 10975845 zobellia_3262 Zobellia galactanivorans hypothetical protein YP_004737679.1 3763574 R 63186 CDS YP_004737680.1 340619227 10975846 complement(3764416..3765246) 1 NC_015844.1 Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides; Belongs to the family 1 of the carbohydrate esterases (CE1); Signal peptide cleaved between residues 21 and 22; Localized in the periplasmic space; Specificity unclear; carbohydrate esterase 3765246 10975846 zobellia_3263 Zobellia galactanivorans carbohydrate esterase YP_004737680.1 3764416 R 63186 CDS YP_004737681.1 340619228 10975847 3765405..3765557 1 NC_015844.1 Hypothetical protein; hypothetical protein 3765557 10975847 zobellia_3264 Zobellia galactanivorans hypothetical protein YP_004737681.1 3765405 D 63186 CDS YP_004737682.1 340619229 10975848 complement(3765549..3766325) 1 NC_015844.1 Conserved hypothetical protein. This protein has likely a modular architecture; Localized in the cytoplasm; hypothetical protein 3766325 10975848 zobellia_3265 Zobellia galactanivorans hypothetical protein YP_004737682.1 3765549 R 63186 CDS YP_004737683.1 340619230 10975849 complement(3766703..3767428) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 3767428 10975849 zobellia_3266 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004737683.1 3766703 R 63186 CDS YP_004737684.1 340619231 10975850 3767590..3768474 1 NC_015844.1 Transcriptional regulator belonging to the LysR family. Features a N-terminal helix-turn-helix DNA binding domain and a C-terminal LysR-like substrate binding domain. Localized in the cytoplasm.; Specificity unclear; LysR family transcriptional regulator 3768474 10975850 zobellia_3267 Zobellia galactanivorans LysR family transcriptional regulator YP_004737684.1 3767590 D 63186 CDS YP_004737685.1 340619232 10975851 complement(3768627..3769223) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3769223 10975851 zobellia_3268 Zobellia galactanivorans periplasmic protein YP_004737685.1 3768627 R 63186 CDS YP_004737686.1 340619233 10975852 complement(3769207..3770001) 1 NC_015844.1 Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides; Belongs to the family 1 of the carbohydrate esterases (CE1); Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Specificity unclear; carbohydrate esterase 3770001 10975852 zobellia_3269 Zobellia galactanivorans carbohydrate esterase YP_004737686.1 3769207 R 63186 CDS YP_004737687.1 340619234 10975853 complement(3770074..3770682) 1 NC_015844.1 The Crp/Fnr-type transcriptional regulators complexe with cyclic AMP and bind to operator sites near the promoter with a C-terminal HTH domain to regulate the transcription of several catabolite-sensitive operons; They predominantly act as transcription activators, but can also be important repressors, and respond to diverse intracellular and exogenous signals; Localized in the cytoplasm; Family membership; Crp/Fnr-type transcriptional regulator 3770682 10975853 zobellia_3270 Zobellia galactanivorans Crp/Fnr-type transcriptional regulator YP_004737687.1 3770074 R 63186 CDS YP_004737688.1 340619235 10975855 3770682..3770951 1 NC_015844.1 Hypothetical protein; hypothetical protein 3770951 10975855 zobellia_3271 Zobellia galactanivorans hypothetical protein YP_004737688.1 3770682 D 63186 CDS YP_004737689.1 340619236 10975856 complement(3771093..3772028) 1 NC_015844.1 The protein NsrA is involved in nisin-resistance. It is a non-peptidase homologuous to peptidases S41. Although the catalytic serine is conserved, the catalytic lysine is replaced by a leucine; Belongs to the family S41 of the peptidases; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Function unclear; Nisin-resistance protein, family S41 3772028 nsrA 10975856 nsrA Zobellia galactanivorans Nisin-resistance protein, family S41 YP_004737689.1 3771093 R 63186 CDS YP_004737690.1 340619237 10978276 complement(3772078..3772212) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3772212 10978276 zobellia_3273 Zobellia galactanivorans hypothetical protein YP_004737690.1 3772078 R 63186 CDS YP_004737691.1 340619238 10975857 3772289..3773866 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to family 11 of transposases; Localized in the cytoplasm; Family membership; transposase, family 11 3773866 10975857 zobellia_3274 Zobellia galactanivorans transposase, family 11 YP_004737691.1 3772289 D 63186 CDS YP_004737692.1 340619239 10975858 complement(3774020..3774745) 1 NC_015844.1 Contains seven transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3774745 10975858 zobellia_3275 Zobellia galactanivorans hypothetical protein YP_004737692.1 3774020 R 63186 CDS YP_004737693.1 340619240 10975859 complement(3774768..3775289) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3775289 10975859 zobellia_3276 Zobellia galactanivorans membrane protein YP_004737693.1 3774768 R 63186 CDS YP_004737694.1 340619241 10975860 complement(3775456..3776952) 1 NC_015844.1 The exact function of this protein is unknown; Belongs to the Amidohydrolase family; Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Family membership; amidohydrolase family protein 3776952 10975860 zobellia_3277 Zobellia galactanivorans amidohydrolase family protein YP_004737694.1 3775456 R 63186 CDS YP_004737695.1 340619242 10975861 3776986..3777186 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3777186 10975861 zobellia_3278 Zobellia galactanivorans hypothetical protein YP_004737695.1 3776986 D 63186 CDS YP_004737696.1 340619243 10975862 complement(3777512..3777718) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3777718 10975862 zobellia_3279 Zobellia galactanivorans hypothetical protein YP_004737696.1 3777512 R 63186 CDS YP_004737697.1 340619244 10975863 complement(3777868..3778065) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3778065 10975863 zobellia_3280 Zobellia galactanivorans hypothetical protein YP_004737697.1 3777868 R 63186 CDS YP_004737698.1 340619245 10975865 complement(3778077..3778730) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Hypothetical protein; hypothetical protein 3778730 10975865 zobellia_3281 Zobellia galactanivorans hypothetical protein YP_004737698.1 3778077 R 63186 CDS YP_004737699.1 340619246 10975866 complement(3779085..3779480) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3779480 10975866 zobellia_3282 Zobellia galactanivorans hypothetical protein YP_004737699.1 3779085 R 63186 CDS YP_004737700.1 340619247 10975867 complement(3780578..3780988) 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 3780988 10975867 zobellia_3283 Zobellia galactanivorans hypothetical protein YP_004737700.1 3780578 R 63186 CDS YP_004737701.1 340619248 10975868 3781254..3782831 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to family 11 of transposases; Localized in the cytoplasm; Family membership; transposase, family 11 3782831 10975868 zobellia_3284 Zobellia galactanivorans transposase, family 11 YP_004737701.1 3781254 D 63186 CDS YP_004737702.1 340619249 10975869 complement(3782924..3785260) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3785260 10975869 zobellia_3285 Zobellia galactanivorans hypothetical protein YP_004737702.1 3782924 R 63186 CDS YP_004737703.1 340619250 10975870 complement(3785594..3786835) 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 3786835 10975870 zobellia_3286 Zobellia galactanivorans hypothetical protein YP_004737703.1 3785594 R 63186 CDS YP_004737704.1 340619251 10975871 complement(3786861..3787961) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3787961 10975871 zobellia_3287 Zobellia galactanivorans membrane protein YP_004737704.1 3786861 R 63186 CDS YP_004737705.1 340619252 10975872 complement(3788177..3790312) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3790312 10975872 zobellia_3288 Zobellia galactanivorans hypothetical protein YP_004737705.1 3788177 R 63186 CDS YP_004737706.1 340619253 10975873 complement(3790635..3790988) 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 3790988 10975873 zobellia_3289 Zobellia galactanivorans hypothetical protein YP_004737706.1 3790635 R 63186 CDS YP_004737707.1 340619254 10975874 complement(3790989..3791654) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3791654 10975874 zobellia_3290 Zobellia galactanivorans membrane protein YP_004737707.1 3790989 R 63186 CDS YP_004737708.1 340619255 10975876 complement(3792068..3793798) 1 NC_015844.1 Erythromycin esterase confers resistance to erythromycin through inactivation by hydrolyzing the lactone ring of the antibiotic. Also contains a N-terminal domain of unknown function. Localized in the cytoplasm.; Hypothetical protein; erythromycin esterase 3793798 ereA 10975876 ereA Zobellia galactanivorans erythromycin esterase YP_004737708.1 3792068 R 63186 CDS YP_004737709.1 340619256 10977785 complement(3794223..3794801) 1 NC_015844.1 Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3794801 10977785 zobellia_3292 Zobellia galactanivorans membrane protein YP_004737709.1 3794223 R 63186 CDS YP_004737710.1 340619257 10975877 complement(3795053..3795580) 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 3795580 10975877 zobellia_3293 Zobellia galactanivorans hypothetical protein YP_004737710.1 3795053 R 63186 CDS YP_004737711.1 340619258 10975878 complement(3795635..3796297) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 3796297 10975878 zobellia_3294 Zobellia galactanivorans hypothetical protein YP_004737711.1 3795635 R 63186 CDS YP_004737712.1 340619259 10975879 complement(3796334..3796951) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3796951 10975879 zobellia_3295 Zobellia galactanivorans hypothetical protein YP_004737712.1 3796334 R 63186 CDS YP_004737713.1 340619260 10975880 complement(3797170..3797751) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 16 and 17; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 3797751 10975880 zobellia_3296 Zobellia galactanivorans hypothetical protein YP_004737713.1 3797170 R 63186 CDS YP_004737714.1 340619261 10975881 3798152..3800008 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Lipoprotein signal peptide cleaved between the residues 23 and 24; Contains four N-terminal tetratrico peptide repeats (TPR) and one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 3800008 10975881 zobellia_3297 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004737714.1 3798152 D 63186 CDS YP_004737715.1 340619262 10975882 3800001..3800738 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, that acts as transcriptional regulator; Family membership; two-component system-response regulator 3800738 10975882 zobellia_3298 Zobellia galactanivorans two-component system-response regulator YP_004737715.1 3800001 D 63186 CDS YP_004737716.1 340619263 10975883 3800846..3801256 1 NC_015844.1 Probably a cytoplasmic protein; hypothetical protein 3801256 10975883 zobellia_3299 Zobellia galactanivorans hypothetical protein YP_004737716.1 3800846 D 63186 CDS YP_004737717.1 340619264 10975884 3801314..3801967 1 NC_015844.1 Probably a cytoplasmic protein; hypothetical protein 3801967 10975884 zobellia_3300 Zobellia galactanivorans hypothetical protein YP_004737717.1 3801314 D 63186 CDS YP_004737718.1 340619265 10975887 3801979..3803259 1 NC_015844.1 Probably a cytoplasmic protein; hypothetical protein 3803259 10975887 zobellia_3301 Zobellia galactanivorans hypothetical protein YP_004737718.1 3801979 D 63186 CDS YP_004737719.1 340619266 10975888 3803271..3804761 1 NC_015844.1 Peptidase family M48 contains metalloendopeptidases. This peptidase contains a single catalytic zinc ion tetrahedrally co-ordinated by two histidines within an HEXXH motif, an as yet undetermined third residue and water. The glutamate within the HEXXH motif is assumed to be a catalytic residue. Localized in the cytoplasm.; Specificity unclear; metalloendopeptidase, family M48 3804761 10975888 zobellia_3302 Zobellia galactanivorans metalloendopeptidase, family M48 YP_004737719.1 3803271 D 63186 CDS YP_004737720.1 340619267 10975889 complement(3804776..3804982) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3804982 10975889 zobellia_3303 Zobellia galactanivorans hypothetical protein YP_004737720.1 3804776 R 63186 CDS YP_004737721.1 340619268 10975890 complement(3805130..3807757) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations. Contains a carboxypeptidase regulatory domain (21-107) and the Plug module (120-210) acting as a channel gate. The signal peptide is cleaved between the residues 16 and 17.; Family membership; TonB-dependent Receptor 3807757 10975890 zobellia_3304 Zobellia galactanivorans TonB-dependent Receptor YP_004737721.1 3805130 R 63186 CDS YP_004737722.1 340619269 10975891 complement(3807758..3808543) 1 NC_015844.1 Signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; hypothetical protein 3808543 10975891 zobellia_3305 Zobellia galactanivorans hypothetical protein YP_004737722.1 3807758 R 63186 CDS YP_004737723.1 340619270 10975892 3808688..3808936 1 NC_015844.1 Hypothetical protein; hypothetical protein 3808936 10975892 zobellia_3306 Zobellia galactanivorans hypothetical protein YP_004737723.1 3808688 D 63186 CDS YP_004737724.1 340619271 10975893 complement(3809163..3809633) 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 3809633 10975893 zobellia_3307 Zobellia galactanivorans hypothetical protein YP_004737724.1 3809163 R 63186 CDS YP_004737725.1 340619272 10975894 complement(3809727..3810134) 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 3810134 10975894 zobellia_3308 Zobellia galactanivorans hypothetical protein YP_004737725.1 3809727 R 63186 CDS YP_004737726.1 340619273 10975895 complement(3810365..3811132) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3811132 10975895 zobellia_3309 Zobellia galactanivorans hypothetical protein YP_004737726.1 3810365 R 63186 CDS YP_004737727.1 340619274 10975896 complement(3811204..3811983) 1 NC_015844.1 CutF is involved in copper homeostasis. Could be involved in both copper efflux and the delivery of copper to copper-dependent enzymes; Contains a C-terminal domain of unknown function DUF306; Prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the cytoplasmic and/or outer membrane; High confidence in function and specificity; Copper homeostasis protein CutF 3811983 cutF 10975896 cutF Zobellia galactanivorans Copper homeostasis protein CutF YP_004737727.1 3811204 R 63186 CDS YP_004737728.1 340619275 10977693 complement(3812210..3812842) 1 NC_015844.1 Contains an uncleaved signal sequence; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3812842 10977693 zobellia_3311 Zobellia galactanivorans hypothetical protein YP_004737728.1 3812210 R 63186 CDS YP_004737729.1 340619276 10975898 complement(3812861..3812998) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3812998 10975898 zobellia_3312 Zobellia galactanivorans hypothetical protein YP_004737729.1 3812861 R 63186 CDS YP_004737730.1 340619277 10975899 complement(3813050..3814033) 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 3814033 10975899 zobellia_3313 Zobellia galactanivorans hypothetical protein YP_004737730.1 3813050 R 63186 CDS YP_004737731.1 340619278 10975900 complement(3814126..3814785) 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 17 and 18; Possibly localized in the outer membrane; Hypothetical protein; hypothetical protein 3814785 10975900 zobellia_3314 Zobellia galactanivorans hypothetical protein YP_004737731.1 3814126 R 63186 CDS YP_004737732.1 340619279 10975901 complement(3814816..3815073) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3815073 10975901 zobellia_3315 Zobellia galactanivorans hypothetical protein YP_004737732.1 3814816 R 63186 CDS YP_004737733.1 340619280 10975902 3815245..3815484 1 NC_015844.1 Hypothetical protein; hypothetical protein 3815484 10975902 zobellia_3316 Zobellia galactanivorans hypothetical protein YP_004737733.1 3815245 D 63186 CDS YP_004737734.1 340619281 10975903 complement(3815446..3816021) 1 NC_015844.1 The Crp/Fnr-type transcriptional regulators complexe with cyclic AMP and bind to operator sites near the promoter with a C-terminal HTH domain to regulate the transcription of several catabolite-sensitive operons; They predominantly act as transcription activators, but can also be important repressors, and respond to diverse intracellular and exogenous signals; Localized in the cytoplasm; Family membership; Crp/Fnr-type transcriptional regulator 3816021 10975903 zobellia_3317 Zobellia galactanivorans Crp/Fnr-type transcriptional regulator YP_004737734.1 3815446 R 63186 CDS YP_004737735.1 340619282 10975904 complement(3816022..3816684) 1 NC_015844.1 3,4-Dihydroxy-2-butanone 4-phosphate (DHBP) synthase catalyzes the formation of DHBP from ribulose 5- phosphate. DHBP serves as the biosynthetic precursor for the xylene ring of riboflavin. Localized in the cytoplasm.; High confidence in function and specificity; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3816684 ribB 10975904 ribB Zobellia galactanivorans 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_004737735.1 3816022 R 63186 CDS YP_004737736.1 340619284 10978460 complement(3817061..3818251) 1 NC_015844.1 Modular enzyme containing a N-terminal Fibronectin type III domain and a C-terminal metallophosphoesterase domain. The most conserved regions in the metallophosphoesterase family centre around the metal chelating residues; Signal peptide cleaved between the residues 28 and 29; Localized in the periplasm; Specificity unclear; metallophosphoesterase 3818251 10978460 zobellia_3320 Zobellia galactanivorans metallophosphoesterase YP_004737736.1 3817061 R 63186 CDS YP_004737737.1 340619283 10975906 3818240..3818455 1 NC_015844.1 Hypothetical protein; hypothetical protein 3818455 10975906 zobellia_3319 Zobellia galactanivorans hypothetical protein YP_004737737.1 3818240 D 63186 CDS YP_004737738.1 340619285 10975905 3818573..3818773 1 NC_015844.1 Hypothetical protein; hypothetical protein 3818773 10975905 zobellia_3321 Zobellia galactanivorans hypothetical protein YP_004737738.1 3818573 D 63186 CDS YP_004737739.1 340619286 10975907 complement(3818869..3819642) 1 NC_015844.1 Consists of a C-terminal alpha-L-fucosidase domain; The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); High confidence in function and specificity; alpha-L-fucosidase, C-terminal fragment 3819642 10975907 zobellia_3322 Zobellia galactanivorans alpha-L-fucosidase, C-terminal fragment YP_004737739.1 3818869 R 63186 CDS YP_004737740.1 340619287 10975908 complement(3819763..3820674) 1 NC_015844.1 Consists of an N-terminal alpha-L-fucosidase domain; The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha- L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Contains a transmembrane segment; Localized in the cytoplasmic membrane; High confidence in function and specificity; alpha-L-fucosidase, N-terminal fragment 3820674 10975908 zobellia_3323 Zobellia galactanivorans alpha-L-fucosidase, N-terminal fragment YP_004737740.1 3819763 R 63186 CDS YP_004737741.1 340619288 10975909 complement(3821035..3821703) 1 NC_015844.1 Enzyme responsible for synthesis of pseudouridine from uracil in tRNA or rRNA by rotation of the C1'-N-1 glycosidic bond of uridine to a C1'-C5; Belongs to the pseudouridine synthase RluA family; localized in the cytoplasm; Specificity unclear; RNA pseudouridine synthase 3821703 10975909 zobellia_3324 Zobellia galactanivorans RNA pseudouridine synthase YP_004737741.1 3821035 R 63186 CDS YP_004737742.1 340619289 10975910 complement(3821747..3823699) 1 NC_015844.1 Radical SAM proteins catalyze diverse reactions, including unusual methylations, isomerization, sulphur insertion, ring formation, anaerobic oxidation and protein radical formation. Evidence exists that these proteins generate a radical species by reductive cleavage of S:-adenosylmethionine (SAM) through an unusual Fe-S center. The exact function of this protein is unclear. Localized in the cytoplasm.; Family membership; Radical SAM superfamily protein 3823699 10975910 zobellia_3325 Zobellia galactanivorans Radical SAM superfamily protein YP_004737742.1 3821747 R 63186 CDS YP_004737743.1 340619290 10975911 complement(3824286..3825302) 1 NC_015844.1 Thiosulfate:quinone oxidoreductase (TQO), also known as thiosulfate dehydrogenase (quinone), is involved in sulfur oxidation pathway. TQO oxidized thiosulphate with tetrathionate as product and ferricyanide or decyl ubiquinone (DQ) as electron acceptors. In the archaeon Acidianus ambivalens, TQO is constituted by a large subunit, DoxD, and a small subunit, DoxA. Here, DoxD and DoxA are fused and constitute the N- and C-terminal domains of this enzyme, respectively. Features five transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; thiosulfate:quinone oxidoreductase 3825302 doxDA 10975911 doxDA Zobellia galactanivorans thiosulfate:quinone oxidoreductase YP_004737743.1 3824286 R 63186 CDS YP_004737744.1 340619291 10977758 complement(3825472..3825849) 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 27 and 28; Possibly localized in the outer membrane; Hypothetical protein; hypothetical protein 3825849 10977758 zobellia_3327 Zobellia galactanivorans hypothetical protein YP_004737744.1 3825472 R 63186 CDS YP_004737745.1 340619292 10975912 complement(3826174..3826671) 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 3826671 10975912 zobellia_3328 Zobellia galactanivorans hypothetical protein YP_004737745.1 3826174 R 63186 CDS YP_004737746.1 340619293 10975913 complement(3826983..3828161) 1 NC_015844.1 Protein that displays two parts: a N-terminal part that cooperatively binds calcium ions by two EF-hand domains and a conserved C-terminal part of unknown function; Putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 3828161 10975913 zobellia_3329 Zobellia galactanivorans membrane protein YP_004737746.1 3826983 R 63186 CDS YP_004737747.1 340619294 10975914 3828270..3828704 1 NC_015844.1 Possible inactive fragment of transposase. The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Could belong to the family 11 of transposases; Putatively localized in the cytoplasm; Conserved hypothetical protein; hypothetical protein 3828704 10975914 zobellia_3330 Zobellia galactanivorans hypothetical protein YP_004737747.1 3828270 D 63186 CDS YP_004737748.1 340619295 10975916 complement(3828771..3829184) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3829184 10975916 zobellia_3331 Zobellia galactanivorans hypothetical protein YP_004737748.1 3828771 R 63186 CDS YP_004737749.1 340619296 10975917 complement(3829490..3830257) 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3830257 10975917 zobellia_3332 Zobellia galactanivorans membrane protein YP_004737749.1 3829490 R 63186 CDS YP_004737750.1 340619297 10975918 complement(3830889..3832166) 1 NC_015844.1 Chloride channels constitute an evolutionarily well-conserved family of voltage-gated channels that are structurally unrelated to the other known voltage-gated channels. Features nine transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; voltage-gated chloride channel 3832166 10975918 zobellia_3333 Zobellia galactanivorans voltage-gated chloride channel YP_004737750.1 3830889 R 63186 CDS YP_004737751.1 340619298 10975919 complement(3832508..3834031) 1 NC_015844.1 Protein that shares one central PKD module (146-230). The presence of this domain would suggest that the protein possess an extracellular segment; Probably the PKD module functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Family membership; PKD-containing protein 3834031 10975919 zobellia_3334 Zobellia galactanivorans PKD-containing protein YP_004737751.1 3832508 R 63186 CDS YP_004737752.1 340619299 10975920 complement(3834056..3834988) 1 NC_015844.1 Contains a lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the cytoplasmic and/or outer membrane; Hypothetical protein; hypothetical protein 3834988 10975920 zobellia_3335 Zobellia galactanivorans hypothetical protein YP_004737752.1 3834056 R 63186 CDS YP_004737753.1 340619300 10975921 complement(3834975..3836819) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 29 and 30; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 3836819 10975921 zobellia_3336 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737753.1 3834975 R 63186 CDS YP_004737754.1 340619301 10975922 complement(3836820..3839645) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Usually; Contains a Plug module (43-138) acting as a channel gate; The signal peptide is cleaved between the residues 23 and 24; Family membership; TonB-dependent Receptor 3839645 10975922 zobellia_3337 Zobellia galactanivorans TonB-dependent Receptor YP_004737754.1 3836820 R 63186 CDS YP_004737755.1 340619302 10975923 complement(3839665..3841581) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 23 and 24; Probably localized in the outer membrane; Family membership; SusD/RagB family protein 3841581 10975923 zobellia_3338 Zobellia galactanivorans SusD/RagB family protein YP_004737755.1 3839665 R 63186 CDS YP_004737756.1 340619303 10975924 complement(3841584..3844739) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (33-108) and the Plug module (124-231) acting as a channel gate; The signal peptide is cleaved between the residues 30 and 31; Family membership; TonB-dependent Receptor 3844739 10975924 zobellia_3339 Zobellia galactanivorans TonB-dependent Receptor YP_004737756.1 3841584 R 63186 CDS YP_004737757.1 340619304 10975925 complement(3845347..3847206) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3847206 10975925 zobellia_3340 Zobellia galactanivorans periplasmic protein YP_004737757.1 3845347 R 63186 CDS YP_004737758.1 340619305 10975927 complement(3847234..3847452) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3847452 10975927 zobellia_3341 Zobellia galactanivorans hypothetical protein YP_004737758.1 3847234 R 63186 CDS YP_004737759.1 340619306 10975928 3847669..3848841 1 NC_015844.1 Contains a central transmembrane helix; Localized in the cytoplasmic membrane.; hypothetical protein 3848841 10975928 zobellia_3342 Zobellia galactanivorans hypothetical protein YP_004737759.1 3847669 D 63186 CDS YP_004737760.1 340619307 10975929 complement(3849117..3850160) 1 NC_015844.1 The LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of operons; They contain a N-terminal lacI-type HTH domain involved in the binding of the protein to the operator sequences in the DNA and a C- terminal periplasmic binding protein domain that are the primary receptors for chemotaxis and transport of many sugar based solutes that act as inducers; Localized in the cytoplasm; Family membership; LacI-type transcriptional regulator 3850160 10975929 zobellia_3343 Zobellia galactanivorans LacI-type transcriptional regulator YP_004737760.1 3849117 R 63186 CDS YP_004737761.1 340619308 10975930 3850413..3853511 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (40-114) and the Plug module (131-254) acting as a channel gate; The signal peptide is cleaved between the residues 35 and 36; Family membership; TonB-dependent Receptor 3853511 10975930 zobellia_3344 Zobellia galactanivorans TonB-dependent Receptor YP_004737761.1 3850413 D 63186 CDS YP_004737762.1 340619309 10975931 3853523..3854887 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer;Contains a lipoprotein signal peptide cleaved between the residues 18 and 19; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 3854887 10975931 zobellia_3345 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737762.1 3853523 D 63186 CDS YP_004737763.1 340619310 10975932 3854926..3856368 1 NC_015844.1 Protein containing an N-terminal FAS1 (or BIgH3) module. In eucariotic cells, this module is involved in the process of cell adhesion. Contains a signal peptide cleaved between the residues 24 and 25. Localized in the outer membrane.; Hypothetical protein; fasciclin family protein 3856368 10975932 zobellia_3346 Zobellia galactanivorans fasciclin family protein YP_004737763.1 3854926 D 63186 CDS YP_004737764.1 340619311 10975933 3856386..3857162 1 NC_015844.1 Glycoside hydrolases hydrolyse the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non-carbohydrate moiety. Belongs to the family 16 of the glycoside hydrolases. Contains a signal peptide of lipoprotein cleaved between the residues 30 and 31. Localized in the outer membrane.; Specificity unclear; glycoside hydrolase 3857162 10975933 zobellia_3347 Zobellia galactanivorans glycoside hydrolase YP_004737764.1 3856386 D 63186 CDS YP_004737765.1 340619312 10975934 3857209..3857970 1 NC_015844.1 Glucosamine-6-phosphate deaminase or Glucosamine-6-phosphate isomerase catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion in the N-acetylglucosamine (GlcNAC) utilization pathway; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family; Localized in the cytoplasm; High confidence in function and specificity; glucosamine-6-phosphate deaminase 3857970 nagB1 10975934 nagB1 Zobellia galactanivorans glucosamine-6-phosphate deaminase YP_004737765.1 3857209 D 63186 CDS YP_004737766.1 340619313 10978226 3857999..3859561 1 NC_015844.1 Glycoside hydrolases hydrolyse the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non-carbohydrate moiety. Belongs to the family 20 of the glycoside hydrolases. Carbonyl oxygen of the C-2 acetamido group of the substrate acts as the catalytic nucleophile/base in the family GH20. Features a signal peptide cleaved between residues 27 and 28. Localized in the periplasm.; Specificity unclear; glycoside hydrolase 3859561 10978226 zobellia_3349 Zobellia galactanivorans glycoside hydrolase YP_004737766.1 3857999 D 63186 CDS YP_004737767.1 340619314 10975935 3859621..3861099 1 NC_015844.1 Sodium/substrate symport is a mechanism of solute transport across cytoplasmic membranes cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains 13 transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sodium/solute symporter 3861099 10975935 zobellia_3350 Zobellia galactanivorans sodium/solute symporter YP_004737767.1 3859621 D 63186 CDS YP_004737768.1 340619315 10975937 3861104..3862252 1 NC_015844.1 N-acetylglucosamine-6-phosphate deacetylase, induced by N-acetylglucosamine, hydrolyses the N-acetyl-D-glucosamine 6-phosphate to D-glucosamine 6-phosphate in the N-acetylglucosamine utilization pathway; Belongs to the Amidohydrolase family; Localized in the cytoplasm; High confidence in function and specificity; N-acetylglucosamine-6-phosphate deacetylase 3862252 nagA 10975937 nagA Zobellia galactanivorans N-acetylglucosamine-6-phosphate deacetylase YP_004737768.1 3861104 D 63186 CDS YP_004737769.1 340619316 10978224 3862308..3863900 1 NC_015844.1 Beta-N-acetylhexosaminidase catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. Carbonyl oxygen of the C-2 acetamido group of the substrate acts as the catalytic nucleophile/base; Belongs to the family 20 of the glycoside hydrolases (GH20); Signal peptide cleaved between residues 22 and 23; Localized in the periplasmic space; High confidence in function and specificity; beta-N-acetylhexosaminidase 3863900 nahA3 10978224 nahA3 Zobellia galactanivorans beta-N-acetylhexosaminidase YP_004737769.1 3862308 D 63186 CDS YP_004737770.1 340619317 10978230 complement(3863970..3865034) 1 NC_015844.1 Serine peptidase belonging to the family S12. The active site residues Ser and Lys form the catalytic dyad and are found in the motif Ser-Xaa-Thr-Lys; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18, Localized in the outer membrane; Function unclear; serine peptidase 3865034 10978230 zobellia_3353 Zobellia galactanivorans serine peptidase YP_004737770.1 3863970 R 63186 CDS YP_004737771.1 340619318 10975938 3865319..3865948 1 NC_015844.1 Conserved hypothetical protein including an N-terminal region rich in glycine, reminiscent of the collagen triple helix repeats (GxxG). Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3865948 10975938 zobellia_3354 Zobellia galactanivorans lipoprotein YP_004737771.1 3865319 D 63186 CDS YP_004737772.1 340619319 10975939 complement(3866163..3866738) 1 NC_015844.1 This peptidase belongs to the family 56 of the cysteine peptidases (C56). The catalytic diad is constituted by two consecutive residues, Cys and His. The enzyme forms a hexameric ring structure, and the active sites are proposed to be formed at the interfaces between three pairs of monomers. Localized in the cytoplasm.; Specificity unclear; intracellular peptidase 3866738 pfpI 10975939 pfpI Zobellia galactanivorans intracellular peptidase YP_004737772.1 3866163 R 63186 CDS YP_004737773.1 340619320 10978333 3867296..3870418 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (25-98) and the Plug module (114-221) acting as a channel gate; The signal peptide is cleaved between the residues 22 and 23; Family membership; TonB-dependent receptor 3870418 10978333 zobellia_3356 Zobellia galactanivorans TonB-dependent receptor YP_004737773.1 3867296 D 63186 CDS YP_004737774.1 340619321 10975940 3870430..3872094 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the cytoplasmic membrane; Family membership; SusD/RagB family lipoprotein 3872094 10975940 zobellia_3357 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737774.1 3870430 D 63186 CDS YP_004737775.1 340619322 10975941 complement(3872357..3873103) 1 NC_015844.1 This conserved protein belongs to the DUF71 family, which is predicted to bind ATP. It features a strongly conserved motif SGGKD at the N terminus. It is a two-domain protein with a N-terminal Rossmann fold domain and a C-terminal alpha/beta domain. Localized in the cytoplasm.; Family membership; hypothetical protein 3873103 10975941 zobellia_3358 Zobellia galactanivorans hypothetical protein YP_004737775.1 3872357 R 63186 CDS YP_004737776.1 340619323 10975942 complement(3873142..3873255) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3873255 10975942 zobellia_3359 Zobellia galactanivorans hypothetical protein YP_004737776.1 3873142 R 63186 CDS YP_004737777.1 340619324 10975943 complement(3873330..3874583) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3874583 10975943 zobellia_3360 Zobellia galactanivorans hypothetical protein YP_004737777.1 3873330 R 63186 CDS YP_004737778.1 340619325 10975945 3874835..3875092 1 NC_015844.1 Hypothetical protein; hypothetical protein 3875092 10975945 zobellia_3361 Zobellia galactanivorans hypothetical protein YP_004737778.1 3874835 D 63186 CDS YP_004737779.1 340619326 10975946 complement(3876138..3877271) 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 3877271 10975946 zobellia_3362 Zobellia galactanivorans hypothetical protein YP_004737779.1 3876138 R 63186 CDS YP_004737780.1 340619327 10975947 complement(3877625..3878758) 1 NC_015844.1 Contains four N-terminal transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3878758 10975947 zobellia_3363 Zobellia galactanivorans membrane protein YP_004737780.1 3877625 R 63186 CDS YP_004737781.1 340619328 10975948 complement(3878842..3879081) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3879081 10975948 zobellia_3364 Zobellia galactanivorans hypothetical protein YP_004737781.1 3878842 R 63186 CDS YP_004737782.1 340619329 10975949 3879171..3879485 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3879485 10975949 zobellia_3365 Zobellia galactanivorans hypothetical protein YP_004737782.1 3879171 D 63186 CDS YP_004737783.1 340619330 10975950 3879584..3881179 1 NC_015844.1 Protein containing a C-terminal STAS domain (Sulphate Transporter and AntiSigma factor antagonist), which has been suggested to have have a general NTP binding function; belongs to the sulfate transporter family; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sulfate transporter 3881179 10975950 zobellia_3366 Zobellia galactanivorans sulfate transporter YP_004737783.1 3879584 D 63186 CDS YP_004737784.1 340619331 10975951 3881199..3881840 1 NC_015844.1 Carbonate dehydratase (or carbonic anhydrases) is a zinc metalloenzyme which catalyzes the reversible hydration of carbon dioxide . It belongs to the beta class of carbonic anhydrases. It forms a homodimer and binds one zinc ion by subunit. In bacteria, this enzyme is usually involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase. By this action, it prevents the depletion of cellular bicarbonate Localized in the cytoplasm.; High confidence in function and specificity; carbonate dehydratase 3881840 canA3 10975951 canA3 Zobellia galactanivorans carbonate dehydratase YP_004737784.1 3881199 D 63186 CDS YP_004737785.1 340619332 10977617 complement(3882026..3882172) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3882172 10977617 zobellia_3368 Zobellia galactanivorans hypothetical protein YP_004737785.1 3882026 R 63186 CDS YP_004737786.1 340619333 10975952 3882267..3882371 1 NC_015844.1 Hypothetical protein; hypothetical protein 3882371 10975952 zobellia_3369 Zobellia galactanivorans hypothetical protein YP_004737786.1 3882267 D 63186 CDS YP_004737787.1 340619334 10975953 3882514..3883194 1 NC_015844.1 This protein belongs to the zinc-dependent beta-lactamase superfamily and is likely a metal-dependent hydrolase; Localized in the cytoplasm; Family membership; metal-dependent hydrolase 3883194 10975953 zobellia_3370 Zobellia galactanivorans metal-dependent hydrolase YP_004737787.1 3882514 D 63186 CDS YP_004737788.1 340619335 10975955 complement(3883291..3883686) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3883686 10975955 zobellia_3371 Zobellia galactanivorans hypothetical protein YP_004737788.1 3883291 R 63186 CDS YP_004737789.1 340619336 10975956 complement(3883816..3884298) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3884298 10975956 zobellia_3372 Zobellia galactanivorans hypothetical protein YP_004737789.1 3883816 R 63186 CDS YP_004737790.1 340619337 10975957 complement(3884299..3884655) 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 3884655 10975957 zobellia_3373 Zobellia galactanivorans hypothetical protein YP_004737790.1 3884299 R 63186 CDS YP_004737791.1 340619338 10975958 complement(3885056..3885265) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3885265 10975958 zobellia_3374 Zobellia galactanivorans hypothetical protein YP_004737791.1 3885056 R 63186 CDS YP_004737792.1 340619339 10975959 3885517..3885651 1 NC_015844.1 Hypothetical protein; hypothetical protein 3885651 10975959 zobellia_3375 Zobellia galactanivorans hypothetical protein YP_004737792.1 3885517 D 63186 CDS YP_004737793.1 340619340 10975960 3885700..3886767 1 NC_015844.1 The beta-porphyranases hydrolyse the 1,4-beta-D-galactosidic linkages in porphyrans; Belongs to the family 16 of glycoside hydrolases (GH16); Signal peptide of lipoprotein cleaved between the residues 18 and 19; Localized in the outer membrane; High confidence in function and specificity; beta-porphyranase C 3886767 porC 10975960 porC Zobellia galactanivorans beta-porphyranase C YP_004737793.1 3885700 D 63186 CDS YP_004737794.1 340619341 10978363 complement(3886868..3887275) 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3887275 10978363 zobellia_3377 Zobellia galactanivorans hypothetical protein YP_004737794.1 3886868 R 63186 CDS YP_004737795.1 340619342 10975961 complement(3887315..3887527) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3887527 10975961 zobellia_3378 Zobellia galactanivorans hypothetical protein YP_004737795.1 3887315 R 63186 CDS YP_004737796.1 340619343 10975962 complement(3887518..3887625) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3887625 10975962 zobellia_3379 Zobellia galactanivorans hypothetical protein YP_004737796.1 3887518 R 63186 CDS YP_004737797.1 340619344 10975963 complement(3887648..3888205) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3888205 10975963 zobellia_3380 Zobellia galactanivorans hypothetical protein YP_004737797.1 3887648 R 63186 CDS YP_004737798.1 340619345 10975964 complement(3888324..3888752) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3888752 10975964 zobellia_3381 Zobellia galactanivorans hypothetical protein YP_004737798.1 3888324 R 63186 CDS YP_004737799.1 340619346 10975965 complement(3888765..3889223) 1 NC_015844.1 Protein fragment found in the C-terminal of the Rhs family proteins; Possibly localized in the cytoplasm; hypothetical protein 3889223 10975965 zobellia_3382 Zobellia galactanivorans hypothetical protein YP_004737799.1 3888765 R 63186 CDS YP_004737800.1 340619347 10975966 complement(3889635..3889877) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3889877 10975966 zobellia_3383 Zobellia galactanivorans hypothetical protein YP_004737800.1 3889635 R 63186 CDS YP_004737801.1 340619348 10975967 complement(3889868..3890071) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3890071 10975967 zobellia_3384 Zobellia galactanivorans hypothetical protein YP_004737801.1 3889868 R 63186 CDS YP_004737802.1 340619349 10975968 complement(3890314..3890859) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3890859 10975968 zobellia_3385 Zobellia galactanivorans hypothetical protein YP_004737802.1 3890314 R 63186 CDS YP_004737803.1 340619350 10975969 complement(3890990..3891418) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3891418 10975969 zobellia_3386 Zobellia galactanivorans hypothetical protein YP_004737803.1 3890990 R 63186 CDS YP_004737804.1 340619351 10975970 complement(3891431..3895492) 1 NC_015844.1 This conserved protein belongs to the Rhs family. It contains numerous repeats featuring a YD dipeptide, the most strongly conserved motif of the repeat. In Escherichia coli, a rhsA mutation reduces K5 biosynthesis suggesting a role for RhsA in coupling biosynthesis and export of capsular polysaccharides. Localized in the cytoplasm.; Family membership; Rhs family protein 3895492 10975970 zobellia_3387 Zobellia galactanivorans Rhs family protein YP_004737804.1 3891431 R 63186 CDS YP_004737805.1 340619352 10975971 complement(3895505..3896842) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3896842 10975971 zobellia_3388 Zobellia galactanivorans hypothetical protein YP_004737805.1 3895505 R 63186 CDS YP_004737806.1 340619353 10975972 complement(3896848..3898629) 1 NC_015844.1 Conserved protein belonging to the Vgr family. The Vgr family proteins are associated with some classes of Rhs elements; Localized in the cytoplasm; Family membership; Vgr family protein 3898629 10975972 zobellia_3389 Zobellia galactanivorans Vgr family protein YP_004737806.1 3896848 R 63186 CDS YP_004737807.1 340619354 10975973 complement(3898792..3898920) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3898920 10975973 zobellia_3390 Zobellia galactanivorans hypothetical protein YP_004737807.1 3898792 R 63186 CDS YP_004737808.1 340619355 10975974 complement(3899676..3900314) 1 NC_015844.1 Contains six transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3900314 10975974 zobellia_3391 Zobellia galactanivorans hypothetical protein YP_004737808.1 3899676 R 63186 CDS YP_004737809.1 340619356 10975975 complement(3900416..3900571) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3900571 10975975 zobellia_3392 Zobellia galactanivorans hypothetical protein YP_004737809.1 3900416 R 63186 CDS YP_004737810.1 340619357 10975976 complement(3901025..3901939) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 3901939 10975976 zobellia_3393 Zobellia galactanivorans hypothetical protein YP_004737810.1 3901025 R 63186 CDS YP_004737811.1 340619358 10975977 complement(3902304..3902888) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 3902888 10975977 zobellia_3394 Zobellia galactanivorans hypothetical protein YP_004737811.1 3902304 R 63186 CDS YP_004737812.1 340619359 10975978 complement(3902956..3903393) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3903393 10975978 zobellia_3395 Zobellia galactanivorans hypothetical protein YP_004737812.1 3902956 R 63186 CDS YP_004737813.1 340619360 10975979 complement(3903557..3903892) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the outer membrane; Hypothetical protein; hypothetical protein 3903892 10975979 zobellia_3396 Zobellia galactanivorans hypothetical protein YP_004737813.1 3903557 R 63186 CDS YP_004737814.1 340619361 10975980 complement(3904047..3904742) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3904742 10975980 zobellia_3397 Zobellia galactanivorans hypothetical protein YP_004737814.1 3904047 R 63186 CDS YP_004737815.1 340619362 10975981 complement(3905344..3906432) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3906432 10975981 zobellia_3398 Zobellia galactanivorans hypothetical protein YP_004737815.1 3905344 R 63186 CDS YP_004737816.1 340619363 10975982 3906774..3907025 1 NC_015844.1 Hypothetical protein; hypothetical protein 3907025 10975982 zobellia_3399 Zobellia galactanivorans hypothetical protein YP_004737816.1 3906774 D 63186 CDS YP_004737817.1 340619364 10975983 complement(3907302..3907937) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3907937 10975983 zobellia_3400 Zobellia galactanivorans hypothetical protein YP_004737817.1 3907302 R 63186 CDS YP_004737818.1 340619365 10975985 3908056..3908274 1 NC_015844.1 Hypothetical protein; hypothetical protein 3908274 10975985 zobellia_3401 Zobellia galactanivorans hypothetical protein YP_004737818.1 3908056 D 63186 CDS YP_004737819.1 340619366 10975986 complement(3908237..3909055) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3909055 10975986 zobellia_3402 Zobellia galactanivorans hypothetical protein YP_004737819.1 3908237 R 63186 CDS YP_004737820.1 340619367 10975987 complement(3909302..3910057) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3910057 10975987 zobellia_3403 Zobellia galactanivorans hypothetical protein YP_004737820.1 3909302 R 63186 CDS YP_004737821.1 340619368 10975988 3910285..3910872 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3910872 10975988 zobellia_3404 Zobellia galactanivorans hypothetical protein YP_004737821.1 3910285 D 63186 CDS YP_004737822.1 340619369 10975989 complement(3911131..3911679) 1 NC_015844.1 hypothetical protein 3911679 10975989 zobellia_3405 Zobellia galactanivorans hypothetical protein YP_004737822.1 3911131 R 63186 CDS YP_004737823.1 340619370 10975990 complement(3911782..3911910) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3911910 10975990 zobellia_3406 Zobellia galactanivorans hypothetical protein YP_004737823.1 3911782 R 63186 CDS YP_004737824.1 340619371 10975991 3911925..3912116 1 NC_015844.1 Hypothetical protein; hypothetical protein 3912116 10975991 zobellia_3407 Zobellia galactanivorans hypothetical protein YP_004737824.1 3911925 D 63186 CDS YP_004737825.1 340619372 10975992 complement(3912211..3912336) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3912336 10975992 zobellia_3408 Zobellia galactanivorans hypothetical protein YP_004737825.1 3912211 R 63186 CDS YP_004737826.1 340619373 10975993 3912461..3913291 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 3913291 10975993 zobellia_3409 Zobellia galactanivorans AraC family transcriptional regulator YP_004737826.1 3912461 D 63186 CDS YP_004737827.1 340619374 10975994 3913495..3914115 1 NC_015844.1 Conserved hypothetical protein including an N-terminal region rich in glycine, reminiscent of the collagen triple helix repeats (GxxG). Contains a prokaryotic lipoprotein signal peptide cleaved between tyhe residues 22 and 23; Localized in the outer membrane; Function unclear; lipoprotein 3914115 10975994 zobellia_3410 Zobellia galactanivorans lipoprotein YP_004737827.1 3913495 D 63186 CDS YP_004737828.1 340619375 10975995 3914193..3914447 1 NC_015844.1 Hypothetical protein; hypothetical protein 3914447 10975995 zobellia_3411 Zobellia galactanivorans hypothetical protein YP_004737828.1 3914193 D 63186 CDS YP_004737829.1 340619376 10975996 3914786..3915766 1 NC_015844.1 Protein containing six Kelch repeats. The kelch motif forms a beta sheet and several of these sheets associate to form a beta propeller structure; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 23 and 24; Localized in the outer membrane; Family membership; Kelch repeat-containing protein 3915766 10975996 zobellia_3412 Zobellia galactanivorans Kelch repeat-containing protein YP_004737829.1 3914786 D 63186 CDS YP_004737830.1 340619377 10975997 complement(3915763..3915900) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3915900 10975997 zobellia_3413 Zobellia galactanivorans hypothetical protein YP_004737830.1 3915763 R 63186 CDS YP_004737831.1 340619378 10975998 3915915..3916040 1 NC_015844.1 Hypothetical protein; hypothetical protein 3916040 10975998 zobellia_3414 Zobellia galactanivorans hypothetical protein YP_004737831.1 3915915 D 63186 CDS YP_004737832.1 340619379 10975999 3916037..3916963 1 NC_015844.1 lipoprotein containing five tandem peptide repeats of 25 or 26 residues in the C-terminal part of the protein suggesting that this protein is a surface protein; Belongs to the DUF285 family; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 23 and 24; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3916963 10975999 zobellia_3415 Zobellia galactanivorans lipoprotein YP_004737832.1 3916037 D 63186 CDS YP_004737833.1 340619380 10976000 complement(3917266..3918324) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3918324 10976000 zobellia_3416 Zobellia galactanivorans hypothetical protein YP_004737833.1 3917266 R 63186 CDS YP_004737834.1 340619381 10976001 complement(3918417..3919391) 1 NC_015844.1 Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3919391 10976001 zobellia_3417 Zobellia galactanivorans membrane protein YP_004737834.1 3918417 R 63186 CDS YP_004737835.1 340619382 10976002 3919611..3920198 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3920198 10976002 zobellia_3418 Zobellia galactanivorans hypothetical protein YP_004737835.1 3919611 D 63186 CDS YP_004737836.1 340619383 10976003 3920183..3920281 1 NC_015844.1 Hypothetical protein; hypothetical protein 3920281 10976003 zobellia_3419 Zobellia galactanivorans hypothetical protein YP_004737836.1 3920183 D 63186 CDS YP_004737837.1 340619384 10976004 complement(3920290..3921312) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3921312 10976004 zobellia_3420 Zobellia galactanivorans hypothetical protein YP_004737837.1 3920290 R 63186 CDS YP_004737838.1 340619385 10976005 complement(3921294..3922853) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3922853 10976005 zobellia_3421 Zobellia galactanivorans hypothetical protein YP_004737838.1 3921294 R 63186 CDS YP_004737839.1 340619386 10976006 3923147..3924727 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to family 11 of transposases; Localized in the cytoplasm; Family membership; transposase, family 11 3924727 10976006 zobellia_3422 Zobellia galactanivorans transposase, family 11 YP_004737839.1 3923147 D 63186 CDS YP_004737840.1 340619387 10976007 3924712..3924822 1 NC_015844.1 Hypothetical protein; hypothetical protein 3924822 10976007 zobellia_3423 Zobellia galactanivorans hypothetical protein YP_004737840.1 3924712 D 63186 CDS YP_004737841.1 340619388 10976008 complement(3924819..3925868) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3925868 10976008 zobellia_3424 Zobellia galactanivorans hypothetical protein YP_004737841.1 3924819 R 63186 CDS YP_004737842.1 340619389 10976009 complement(3926031..3927143) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 3927143 10976009 zobellia_3425 Zobellia galactanivorans hypothetical protein YP_004737842.1 3926031 R 63186 CDS YP_004737843.1 340619390 10976010 complement(3927259..3927399) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3927399 10976010 zobellia_3426 Zobellia galactanivorans hypothetical protein YP_004737843.1 3927259 R 63186 CDS YP_004737844.1 340619391 10976011 complement(3927393..3927563) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3927563 10976011 zobellia_3427 Zobellia galactanivorans hypothetical protein YP_004737844.1 3927393 R 63186 CDS YP_004737845.1 340619392 10976012 3927733..3927903 1 NC_015844.1 Hypothetical protein; hypothetical protein 3927903 10976012 zobellia_3428 Zobellia galactanivorans hypothetical protein YP_004737845.1 3927733 D 63186 CDS YP_004737846.1 340619393 10976013 3927916..3929370 1 NC_015844.1 Oxidoreductase that uses the FAD and NADH as coenzyme; Belongs to the pyridine nucleotide-disulphide oxidoreductase superfamily; Localized in the cytoplasm; Specificity unclear; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 3929370 10976013 zobellia_3429 Zobellia galactanivorans FAD-dependent pyridine nucleotide-disulfide oxidoreductase YP_004737846.1 3927916 D 63186 CDS YP_004737847.1 340619394 10976014 3929449..3929550 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3929550 10976014 zobellia_3430 Zobellia galactanivorans membrane protein YP_004737847.1 3929449 D 63186 CDS YP_004737848.1 340619395 10976015 3929547..3929747 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3929747 10976015 zobellia_3431 Zobellia galactanivorans membrane protein YP_004737848.1 3929547 D 63186 CDS YP_004737849.1 340619396 10976016 3929905..3931206 1 NC_015844.1 The outer membrane efflux proteins (OEP) are composed of two repeats of OEP domain to form a trimeric channel continuous, solvent-accessible conduit that spans both the outer membrane and periplasmic space; May be specialized for the signal peptide independent extracellular secretion of a variety of substrates in Gram-negative bacteria (type I secretion system); Signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Family membership; outer membrane efflux protein 3931206 10976016 zobellia_3432 Zobellia galactanivorans outer membrane efflux protein YP_004737849.1 3929905 D 63186 CDS YP_004737850.1 340619397 10976017 3931311..3932423 1 NC_015844.1 These membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics, solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmique membrane by a N-terminal transmembrane region; Family membership; membrane fusion protein 3932423 10976017 zobellia_3433 Zobellia galactanivorans membrane fusion protein YP_004737850.1 3931311 D 63186 CDS YP_004737851.1 340619398 10976018 3932562..3935795 1 NC_015844.1 Integral membrane protein involved in drug resistance that belongs to the acrB/acrD/acrF family; Contains 12 transmembrane segments and two large periplasmic domains (each exceeding 300 residues) between helices 1 and 2, and helices 7 and 8. The three transmembrane domains form a large, 30-wide central cavity that spans the cytoplasmic membrane and extends to the cytoplasm; Localized in the cytoplasmic membrane; Family membership; multidrug efflux transporter 3935795 10976018 zobellia_3434 Zobellia galactanivorans multidrug efflux transporter YP_004737851.1 3932562 D 63186 CDS YP_004737852.1 340619399 10976019 3935776..3936117 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3936117 10976019 zobellia_3435 Zobellia galactanivorans hypothetical protein YP_004737852.1 3935776 D 63186 CDS YP_004737853.1 340619400 10976020 3936172..3936342 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 3936342 10976020 zobellia_3436 Zobellia galactanivorans membrane protein YP_004737853.1 3936172 D 63186 CDS YP_004737854.1 340619401 10976021 complement(3936441..3938738) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-95) and the Plug module (109-215) acting as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 3938738 10976021 zobellia_3437 Zobellia galactanivorans TonB-dependent Receptor YP_004737854.1 3936441 R 63186 CDS YP_004737855.1 340619402 10976022 complement(3938816..3939154) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3939154 10976022 zobellia_3438 Zobellia galactanivorans hypothetical protein YP_004737855.1 3938816 R 63186 CDS YP_004737856.1 340619403 10976023 3939479..3943651 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one trans membrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 3943651 10976023 zobellia_3439 Zobellia galactanivorans one-component system sensor protein YP_004737856.1 3939479 D 63186 CDS YP_004737857.1 340619404 10976024 complement(3943767..3945668) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 24 and 25; Possibly localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 3945668 10976024 zobellia_3440 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737857.1 3943767 R 63186 CDS YP_004737858.1 340619405 10976025 complement(3945690..3949004) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (50-125) and the Plug module (141-250) acting as a channel gate; The signal peptide is cleaved between the residues 34 and 35; Family membership; TonB-dependent Receptor 3949004 10976025 zobellia_3441 Zobellia galactanivorans TonB-dependent Receptor YP_004737858.1 3945690 R 63186 CDS YP_004737859.1 340619406 10976026 3949088..3949189 1 NC_015844.1 Hypothetical protein; hypothetical protein 3949189 10976026 zobellia_3442 Zobellia galactanivorans hypothetical protein YP_004737859.1 3949088 D 63186 CDS YP_004737860.1 340619407 10976027 complement(3949241..3949348) 1 NC_015844.1 Hypothetical protein; hypothetical protein 3949348 10976027 zobellia_3443 Zobellia galactanivorans hypothetical protein YP_004737860.1 3949241 R 63186 CDS YP_004737861.1 340619408 10976028 3949369..3949578 1 NC_015844.1 Hypothetical protein; hypothetical protein 3949578 10976028 zobellia_3444 Zobellia galactanivorans hypothetical protein YP_004737861.1 3949369 D 63186 CDS YP_004737862.1 340619409 10976029 3949760..3950959 1 NC_015844.1 Unsaturated glucuronyl hydrolase is involved in the catabolism of unsaturated oligosaccharides produced by polysaccharide lyases. UglA catalyzes the hydrolysis of oligosaccharides with unsaturated uronic acids at the nonreducing terminal, to a sugar or an amino sugar, and an unsaturated uronic acid, which is nonenzymatically converted immediately to alpha-keto acid; Belongs to the family 88 of the glycoside hydrolases (GH88); Signal peptide cleaved between residues 22 and 23. Localized in the periplasmic space; Specificity unclear; unsaturated glucuronyl hydrolase 3950959 uglA1 10976029 uglA1 Zobellia galactanivorans unsaturated glucuronyl hydrolase YP_004737862.1 3949760 D 63186 CDS YP_004737863.1 340619410 10978724 3951070..3951933 1 NC_015844.1 Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides; Belongs to the family 10 of the carbohydrate esterases (CE10); Signal peptide cleaved between residues 19 and 20; Localized in the periplasmic space; Specificity unclear; carbohydrate esterase 3951933 10978724 zobellia_3446 Zobellia galactanivorans carbohydrate esterase YP_004737863.1 3951070 D 63186 CDS YP_004737864.1 340619411 10976030 3951938..3953416 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 23; Possible signal peptide of lipoprotein cleaved between the residues 23 and 24; Putatively localized in the outer membrane; Family membership; sulfatase 3953416 10976030 zobellia_3447 Zobellia galactanivorans sulfatase YP_004737864.1 3951938 D 63186 CDS YP_004737865.1 340619412 10976031 3953506..3955023 1 NC_015844.1 Mucin-desulfating sulfatases hydrolyse the sulfate groups from oligosaccharides present in mucins (heavily glycosylated proteins). In the mucins, the main sulfated sugars are N-acetyl-D-glucosamine-6-sulfate, galactose-6-sulfate and galactose-3-sulfate; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 11; Signal peptide cleaved between the residues 22 and 23; Seems localized in the periplasmic space; Specificity unclear; mucin-desulfating sulfatase 3955023 mdsA3 10976031 mdsA3 Zobellia galactanivorans mucin-desulfating sulfatase YP_004737865.1 3953506 D 63186 CDS YP_004737866.1 340619413 10978134 3955065..3957890 1 NC_015844.1 Contains a signal peptide cleaved between the residues 32 and 33; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3957890 10978134 zobellia_3449 Zobellia galactanivorans periplasmic protein YP_004737866.1 3955065 D 63186 CDS YP_004737867.1 340619414 10976032 3957906..3960278 1 NC_015844.1 Protein that likely adopts a right handed parallel beta-helix fold; Contains a C-terminal PDZ domain responsible of protein-protein interaction by binding either the carboxyl-terminal sequences of proteins or internal peptide sequences suggesting that it could be a signaling protein; Prokaryotic lipoprotein signal peptide cleaved between 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; beta-helix fold protein 3960278 10976032 zobellia_3450 Zobellia galactanivorans beta-helix fold protein YP_004737867.1 3957906 D 63186 CDS YP_004737868.1 340619415 10976033 3960295..3962274 1 NC_015844.1 Modular protein with a N-terminal alpha-L-fucosidase module belonging to the family 29 of the glycoside hydrolases (GH29) and a C-terminal acetyl esterase domain belonging to the lipase-GDSL family which includes families 3 and 12 of the carbohydrate esterases (CE3/CE12); Catalytic activities: an alpha-L-fucoside + H2O = L-fucose + an alcohol and an acetic ester + H2O = an alcohol + acetate; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Specificity unclear; alpha-L-fucosidase / acetylesterase 3962274 alfA5 10976033 alfA5 Zobellia galactanivorans alpha-L-fucosidase / acetylesterase YP_004737868.1 3960295 D 63186 CDS YP_004737869.1 340619416 10977498 3962566..3964872 1 NC_015844.1 Polysaccharide lyase catalyses the eliminative cleavage of polysaccharides containing uronic acids. Belongs to the family 15 of the polysaccharide lyases. Up to now, the only known activity in family PL15 is oligo-alginate lyase (EC 4.2.2.-). Features an uncleaved signal peptide. Localized in the cytoplasmic membrane.; Specificity unclear; polysaccharide lyase 3964872 10977498 zobellia_3452 Zobellia galactanivorans polysaccharide lyase YP_004737869.1 3962566 D 63186 CDS YP_004737870.1 340619417 10976034 3964874..3966544 1 NC_015844.1 Possible flavoproteins belonging to the family of pyridine nucleotide-disulphide oxidoreductases; Contains a signal peptide of lipoprotein cleaved between the residues 21 and 22; Localized in the outer membrane; Family membership; pyridine nucleotide-disulfide oxidoreductase 3966544 10976034 zobellia_3453 Zobellia galactanivorans pyridine nucleotide-disulfide oxidoreductase YP_004737870.1 3964874 D 63186 CDS YP_004737871.1 340619418 10976035 3966546..3967271 1 NC_015844.1 Acetylesterase that belongs to the lipase-GDSL Pfam family, which includes families 3 and 12 of the carbohydrate esterases (CE3 and CE12); The conserved catalytic residues are Ser31, Asp172 and His175; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Specificity unclear; lipase-GDSL family acetylesterase 3967271 10976035 zobellia_3454 Zobellia galactanivorans lipase-GDSL family acetylesterase YP_004737871.1 3966546 D 63186 CDS YP_004737872.1 340619419 10976036 3967278..3969110 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Contains a N-terminal transmembrane helix; Possibly localized in the cytoplasmic membrane; Family membership; sulfatase 3969110 10976036 zobellia_3455 Zobellia galactanivorans sulfatase YP_004737872.1 3967278 D 63186 CDS YP_004737873.1 340619420 10976037 3969205..3969984 1 NC_015844.1 Contains a signal peptide cleaved between the residues 32 and 33; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3969984 10976037 zobellia_3456 Zobellia galactanivorans periplasmic protein YP_004737873.1 3969205 D 63186 CDS YP_004737874.1 340619421 10976038 3969981..3971189 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 3971189 10976038 zobellia_3457 Zobellia galactanivorans hypothetical protein YP_004737874.1 3969981 D 63186 CDS YP_004737875.1 340619422 10976039 3971195..3972508 1 NC_015844.1 The Sugars permeases belong to the major facilitator superfamily (MFS) transporters that are single- polypeptide secondary carriers capable only of transporting small solutes (probably sugars in this case) in response to chemiosmotic ion gradients; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; sugar permease 3972508 10976039 zobellia_3458 Zobellia galactanivorans sugar permease YP_004737875.1 3971195 D 63186 CDS YP_004737876.1 340619423 10976040 3972528..3973358 1 NC_015844.1 The 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase or 5-keto-4-deoxyuronate isomerase (DKI isomerase) is involved in the pectin degradation in the pectinolytic microorganisms; Localized in the cytoplasm; High confidence in function and specificity; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 3973358 kduI3 10976040 kduI3 Zobellia galactanivorans 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase YP_004737876.1 3972528 D 63186 CDS YP_004737877.1 340619424 10978064 3973388..3974155 1 NC_015844.1 The 2-keto-3-deoxygluconate oxidoreductase or 2-deoxy-D-gluconate 3-dehydrogenase is involved in the pectin degradation in the pectinolytic microorganisms; Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity; 2-keto-3-deoxygluconate oxidoreductase 3974155 kduD2 10978064 kduD2 Zobellia galactanivorans 2-keto-3-deoxygluconate oxidoreductase YP_004737877.1 3973388 D 63186 CDS YP_004737878.1 340619425 10978061 3974189..3975670 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 28; Putative lipoprotein with a signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; Family membership; sulfatase 3975670 10978061 zobellia_3461 Zobellia galactanivorans sulfatase YP_004737878.1 3974189 D 63186 CDS YP_004737879.1 340619426 10976041 3975686..3977350 1 NC_015844.1 Contains a signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3977350 10976041 zobellia_3462 Zobellia galactanivorans periplasmic protein YP_004737879.1 3975686 D 63186 CDS YP_004737880.1 340619427 10976042 3977512..3978381 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 3978381 10976042 zobellia_3463 Zobellia galactanivorans AraC family transcriptional regulator YP_004737880.1 3977512 D 63186 CDS YP_004737881.1 340619428 10976043 3978903..3980711 1 NC_015844.1 Modular protein that consists of an N-terminal alpha-L-fucosidase module belonging to the family 29 of glycoside hydrolases (GH29), responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside and a C-terminal domain that could be involved in the binding to specific ligands such as carbohydrate or lipids substrates; Signal peptide cleaved between the residue 27 and 28; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 3980711 alfA4 10976043 alfA4 Zobellia galactanivorans alpha-L-fucosidase YP_004737881.1 3978903 D 63186 CDS YP_004737882.1 340619429 10977497 3980785..3982395 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 15; Signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Family membership; sulfatase 3982395 10977497 zobellia_3465 Zobellia galactanivorans sulfatase YP_004737882.1 3980785 D 63186 CDS YP_004737883.1 340619430 10976044 3982434..3983843 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 22; Signal peptide of lipoprotein cleaved between the residues 17 and 18; Possibly localized in the outer membrane and/or in the cytoplasmic membranes; Family membership; sulfatase 3983843 10976044 zobellia_3466 Zobellia galactanivorans sulfatase YP_004737883.1 3982434 D 63186 CDS YP_004737884.1 340619431 10976045 3984212..3987355 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules (here, possibly sulphated sugars) that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (53-126) and the Plug module (142-258) acting as a channel gate; The signal peptide is cleaved between the residues 37 and 38; Family membership; TonB-dependent Receptor 3987355 10976045 zobellia_3467 Zobellia galactanivorans TonB-dependent Receptor YP_004737884.1 3984212 D 63186 CDS YP_004737885.1 340619432 10976046 3987372..3988877 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 23 and 24; Putatively localized in the outer membrane but the determination of the membrane identity for the protein localization is not clear; Family membership; SusD/RagB family lipoprotein 3988877 10976046 zobellia_3468 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737885.1 3987372 D 63186 CDS YP_004737886.1 340619433 10976047 3988949..3990796 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Contains a N-terminal transmembrane helix; Seems localized in the cytoplasmic membrane; Family membership; sulfatase 3990796 10976047 zobellia_3469 Zobellia galactanivorans sulfatase YP_004737886.1 3988949 D 63186 CDS YP_004737887.1 340619434 10976048 3990905..3992419 1 NC_015844.1 Contains a signal peptide cleaved between the residues 34 and 35; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 3992419 10976048 zobellia_3470 Zobellia galactanivorans periplasmic protein YP_004737887.1 3990905 D 63186 CDS YP_004737888.1 340619435 10976049 3992707..3994032 1 NC_015844.1 Galactonate dehydratase converts the D-galactonate to 2-dehydro-3-deoxy-D-galactonate. It is Involved in the galactose metabolism. These enzymes feature a N-terminal domain with a Enolase N-terminal domain-like fold and a C-terminal TIM alpha/beta barrel fold; Belongs to the Mandelate racemase/muconate lactonizing enzyme family; Localized in the cytoplasm; High confidence in function and specificity; galactonate dehydratase 3994032 10976049 zobellia_3471 Zobellia galactanivorans galactonate dehydratase YP_004737888.1 3992707 D 63186 CDS YP_004737889.1 340619436 10976050 3994040..3994816 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 3994816 10976050 zobellia_3472 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004737889.1 3994040 D 63186 CDS YP_004737890.1 340619437 10976051 3994871..3995725 1 NC_015844.1 Conserved protein belonging to the Fumarylacetoacetate hydrolase family, but its exact function is not known; Localized in the cytoplasm.; Family membership; fumarylacetoacetate hydrolase family protein 3995725 10976051 zobellia_3473 Zobellia galactanivorans fumarylacetoacetate hydrolase family protein YP_004737890.1 3994871 D 63186 CDS YP_004737891.1 340619438 10976052 3995733..3996518 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 3996518 10976052 zobellia_3474 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004737891.1 3995733 D 63186 CDS YP_004737892.1 340619439 10976053 3996527..3997846 1 NC_015844.1 FucP mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose. Features twelve transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; L-fucose-proton symporter 3997846 fucP1 10976053 fucP1 Zobellia galactanivorans L-fucose-proton symporter YP_004737892.1 3996527 D 63186 CDS YP_004737893.1 340619440 10977867 3997916..3999085 1 NC_015844.1 L-lactate dehydrogenase is involved in L-lactate degradation converting the L-lactate to pyruvate; Uses flavin mononucleotide (FMN) as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity; l-lactate dehydrogenase 3999085 lldD2 10977867 lldD2 Zobellia galactanivorans l-lactate dehydrogenase YP_004737893.1 3997916 D 63186 CDS YP_004737894.1 340619441 10978096 complement(3999103..3999738) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 14 and 15; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 3999738 10978096 zobellia_3477 Zobellia galactanivorans lipoprotein YP_004737894.1 3999103 R 63186 CDS YP_004737895.1 340619442 10976054 complement(3999888..4000328) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4000328 10976054 zobellia_3478 Zobellia galactanivorans hypothetical protein YP_004737895.1 3999888 R 63186 CDS YP_004737896.1 340619443 10976055 complement(4000388..4001758) 1 NC_015844.1 Conserved protein belonging to the zinc-dependent beta-lactamase superfamily. The active site is characterized by several conserved histidines binding the catalytic zinc ions. The enzymes can bind one or two zinc ions; Localized in the cytoplasm; Function unclear; metallo-beta-lactamase superfamily protein 4001758 10976055 zobellia_3479 Zobellia galactanivorans metallo-beta-lactamase superfamily protein YP_004737896.1 4000388 R 63186 CDS YP_004737897.1 340619444 10976056 complement(4001762..4002607) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4002607 10976056 zobellia_3480 Zobellia galactanivorans hypothetical protein YP_004737897.1 4001762 R 63186 CDS YP_004737898.1 340619445 10976058 complement(4002634..4003539) 1 NC_015844.1 Mechanosensitive channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation; Contains three transmembrane helices; Belongs to the small-conductance MS channels; Localized in the cytoplasmic membrane; Specificity unclear; small-conductance mechanosensitive channel 4003539 10976058 zobellia_3481 Zobellia galactanivorans small-conductance mechanosensitive channel YP_004737898.1 4002634 R 63186 CDS YP_004737899.1 340619446 10976059 4003546..4003653 1 NC_015844.1 Hypothetical protein; hypothetical protein 4003653 10976059 zobellia_3482 Zobellia galactanivorans hypothetical protein YP_004737899.1 4003546 D 63186 CDS YP_004737900.1 340619447 10976060 complement(4003650..4004489) 1 NC_015844.1 Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains two copies of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS- box proteins and bind to DNA; Localized in the cytoplasm; Family membership; universal stress protein 4004489 10976060 zobellia_3483 Zobellia galactanivorans universal stress protein YP_004737900.1 4003650 R 63186 CDS YP_004737901.1 340619448 10976061 complement(4004554..4005405) 1 NC_015844.1 Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains one N-terminal copy of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS-box proteins and bind to DNA; Localized in the cytoplasm; Family membership; universal stress protein 4005405 10976061 zobellia_3484 Zobellia galactanivorans universal stress protein YP_004737901.1 4004554 R 63186 CDS YP_004737902.1 340619449 10976062 4005546..4005845 1 NC_015844.1 Thioredoxin is a small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase; Localized in the cytoplasm; High confidence in function and specificity; thioredoxin 4005845 trxA 10976062 trxA Zobellia galactanivorans thioredoxin YP_004737902.1 4005546 D 63186 CDS YP_004737903.1 340619450 10978707 4005954..4006952 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4006952 10978707 zobellia_3486 Zobellia galactanivorans hypothetical protein YP_004737903.1 4005954 D 63186 CDS YP_004737904.1 340619451 10976063 4007258..4007911 1 NC_015844.1 Uracil phosphoribosyltransferase is involved in pyrimidine metabolism. In presence of diphosphate, it converts UMP to uracyl and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP); Uses magnesium ion as a cofactor; Localized in the cytoplasm; High confidence in function and specificity; uracil phosphoribosyltransferase 4007911 uppA 10976063 uppA Zobellia galactanivorans uracil phosphoribosyltransferase YP_004737904.1 4007258 D 63186 CDS YP_004737905.1 340619452 10978728 complement(4007949..4010456) 1 NC_015844.1 Pmr1 is Aa P-type ATPase responsible for calcium efflux using ATP hydrolysis for energy. Pmr1 controls calcium homeostasis. Belongs to the cation transport P-type ATPase family. Features nine transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; calcium-transporting P-type ATPase 4010456 pmr1 10978728 pmr1 Zobellia galactanivorans calcium-transporting P-type ATPase YP_004737905.1 4007949 R 63186 CDS YP_004737906.1 340619453 10978356 4010664..4011746 1 NC_015844.1 These membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics, solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmique membrane by a N-terminal transmembrane region; Family membership; membrane fusion protein 4011746 10978356 zobellia_3489 Zobellia galactanivorans membrane fusion protein YP_004737906.1 4010664 D 63186 CDS YP_004737907.1 340619454 10976064 4011743..4013005 1 NC_015844.1 Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the cytoplasmic membrane. Such a release is dependent of lolA and of the sorting-signal of the mature lipoprotein (absence of an Asp at position 2); Contains four transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity; lipoprotein releasing system, permease 4013005 lolC 10976064 lolC Zobellia galactanivorans lipoprotein releasing system, permease YP_004737907.1 4011743 D 63186 CDS YP_004737908.1 340619455 10978098 4013016..4013690 1 NC_015844.1 This protein is the nucleotide-binding domain of the Lipoprotein releasing system; Part of the ABC transporter complex lolC (Transmembrane protein), lolD (ATP-binding protein), lolE (Transmembrane protein) involved in the translocation of mature outer membrane- directed lipoproteins, from the inner membrane to the periplasmic chaperone, lolA. Responsible for the formation of the lolA-lipoprotein complex in an ATP-dependent manner; Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; High confidence in function and specificity; lipoprotein releasing system, ATPase component 4013690 lolD 10978098 lolD Zobellia galactanivorans lipoprotein releasing system, ATPase component YP_004737908.1 4013016 D 63186 CDS YP_004737909.1 340619456 10978099 4013797..4014183 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4014183 10978099 zobellia_3492 Zobellia galactanivorans hypothetical protein YP_004737909.1 4013797 D 63186 CDS YP_004737910.1 340619457 10976066 4014198..4015172 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4015172 10976066 zobellia_3493 Zobellia galactanivorans hypothetical protein YP_004737910.1 4014198 D 63186 CDS YP_004737911.1 340619458 10976067 complement(4015189..4015653) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4015653 10976067 zobellia_3494 Zobellia galactanivorans hypothetical protein YP_004737911.1 4015189 R 63186 CDS YP_004737912.1 340619459 10976068 complement(4015631..4015771) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 4015771 10976068 zobellia_3495 Zobellia galactanivorans hypothetical protein YP_004737912.1 4015631 R 63186 CDS YP_004737913.1 340619460 10976069 4015800..4016006 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 4016006 10976069 zobellia_3496 Zobellia galactanivorans hypothetical protein YP_004737913.1 4015800 D 63186 CDS YP_004737914.1 340619461 10976070 complement(4016009..4016437) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4016437 10976070 zobellia_3497 Zobellia galactanivorans hypothetical protein YP_004737914.1 4016009 R 63186 CDS YP_004737915.1 340619462 10976071 complement(4016608..4017123) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Hypothetical protein; hypothetical protein 4017123 10976071 zobellia_3498 Zobellia galactanivorans hypothetical protein YP_004737915.1 4016608 R 63186 CDS YP_004737916.1 340619463 10976072 complement(4017322..4018200) 1 NC_015844.1 Conserved protein belonging to the DUF808 family; Contains five transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 4018200 10976072 zobellia_3499 Zobellia galactanivorans membrane protein YP_004737916.1 4017322 R 63186 CDS YP_004737917.1 340619464 10976073 complement(4018905..4019222) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4019222 10976073 zobellia_3500 Zobellia galactanivorans hypothetical protein YP_004737917.1 4018905 R 63186 CDS YP_004737918.1 340619465 10976076 4019270..4020505 1 NC_015844.1 ROK-type transcriptional repressors are involved in the repression of genes encoding for sugars-utilizing enzymes and are important in the coordination of catabolic and transport operons; Contains a N-terminal helix-turn-helix (HTH) DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA; Belongs to the ROK (nagC/xylR) family; Localized in the cytoplasm; Family membership; ROK-type transcriptional repressor 4020505 10976076 zobellia_3501 Zobellia galactanivorans ROK-type transcriptional repressor YP_004737918.1 4019270 D 63186 CDS YP_004737919.1 340619466 10976077 4020561..4022417 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Putative lipoprotein signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; Family membership; sulfatase 4022417 10976077 zobellia_3502 Zobellia galactanivorans sulfatase YP_004737919.1 4020561 D 63186 CDS YP_004737920.1 340619467 10976078 4022450..4023859 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 25; Lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Family membership; sulfatase 4023859 10976078 zobellia_3503 Zobellia galactanivorans sulfatase YP_004737920.1 4022450 D 63186 CDS YP_004737921.1 340619468 10976079 4024072..4027116 1 NC_015844.1 Large protein containing a central carbohydrate binding module of the family 35 (CBM35) and at least two other domains of unknown function; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Family membership; CBM35-containing protein 4027116 10976079 zobellia_3504 Zobellia galactanivorans CBM35-containing protein YP_004737921.1 4024072 D 63186 CDS YP_004737922.1 340619469 10976080 4027164..4028735 1 NC_015844.1 Mucin-desulfating sulfatases hydrolyse the sulfate groups from oligosaccharides present in mucins (heavily glycosylated proteins). In the mucins, the main sulfated sugars are N-acetyl-D-glucosamine-6-sulfate, galactose-6-sulfate and galactose-3-sulfate; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 11; Putative lipoprotein with a signal peptide cleaved between the residues 23 and 24; Possibly localized in the outer membrane; Specificity unclear; mucin-desulfating sulfatase 4028735 mdsA4 10976080 mdsA4 Zobellia galactanivorans mucin-desulfating sulfatase YP_004737922.1 4027164 D 63186 CDS YP_004737923.1 340619470 10978135 4028748..4029557 1 NC_015844.1 Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides. The catalytic machinery is a Ser-His-Asp triad; Belongs to the family 6 of the carbohydrate esterases CE6); Localized in the cytoplasm; Specificity unclear; carbohydrate esterase 4029557 10978135 zobellia_3506 Zobellia galactanivorans carbohydrate esterase YP_004737923.1 4028748 D 63186 CDS YP_004737924.1 340619471 10976081 4029751..4032924 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (30-103) and the Plug module (119-227) acting as a channel gate; The signal peptide is cleaved between the residues 29 and 30; Family membership; TonB-dependent Receptor 4032924 10976081 zobellia_3507 Zobellia galactanivorans TonB-dependent Receptor YP_004737924.1 4029751 D 63186 CDS YP_004737925.1 340619472 10976082 4032935..4034653 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane but the determination of the membrane identity for the protein localization is not clear; Family membership; SusD/RagB family lipoprotein 4034653 10976082 zobellia_3508 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737925.1 4032935 D 63186 CDS YP_004737926.1 340619473 10976083 complement(4034723..4036156) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Putative lipoprotein signal peptide cleaved between the residues 21 and 22; Possibly localized in the outer membrane; Family membership; sulfatase 4036156 10976083 zobellia_3509 Zobellia galactanivorans sulfatase YP_004737926.1 4034723 R 63186 CDS YP_004737927.1 340619474 10976084 complement(4036299..4040423) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 4040423 10976084 zobellia_3510 Zobellia galactanivorans one-component system sensor protein YP_004737927.1 4036299 R 63186 CDS YP_004737928.1 340619475 10976086 4040752..4043799 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules (here, possibly sulphated sugars) that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; This sequence does not contain of carboxypeptidase regulatory domain. The Plug module (111- 221) acts as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 4043799 10976086 zobellia_3511 Zobellia galactanivorans TonB-dependent Receptor YP_004737928.1 4040752 D 63186 CDS YP_004737929.1 340619476 10976087 4043810..4045369 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 21 and 22; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 4045369 10976087 zobellia_3512 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737929.1 4043810 D 63186 CDS YP_004737930.1 340619477 10976088 4045438..4046904 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Family membership; sulfatase 4046904 10976088 zobellia_3513 Zobellia galactanivorans sulfatase YP_004737930.1 4045438 D 63186 CDS YP_004737931.1 340619478 10976089 4047084..4047737 1 NC_015844.1 Protein that consists of a GDSL-like Lipase/Acylhydrolase domain; Seems to have an uncleavable N-terminal signal sequence; Possibly localized in the cytoplasmic membrane; Family membership; GDSL-like Lipase/acylhydrolase family 4047737 10976089 zobellia_3514 Zobellia galactanivorans GDSL-like Lipase/acylhydrolase family YP_004737931.1 4047084 D 63186 CDS YP_004737932.1 340619479 10976090 4047828..4049456 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; Family membership; sulfatase 4049456 10976090 zobellia_3515 Zobellia galactanivorans sulfatase YP_004737932.1 4047828 D 63186 CDS YP_004737933.1 340619480 10976091 4049499..4051037 1 NC_015844.1 Endo-1,4-beta-xylanase catalyzes the endohydrolysis of 1,4-beta-D-xylosidic linkages in xylans. This enzyme belongs to the family 5 of the glycoside hydrolases. Features a signal peptide cleaved between residues 19 and 20. Localized in the periplasm.; High confidence in function and specificity; endo-1,4-beta-xylanase 4051037 10976091 zobellia_3516 Zobellia galactanivorans endo-1,4-beta-xylanase YP_004737933.1 4049499 D 63186 CDS YP_004737934.1 340619481 10976092 4051065..4053164 1 NC_015844.1 Modular protein consisting of a N-terminal domain belonging to the family 1 of sulfatases and a C-terminal PA14 domain putatively involved in the protein or carbohydrate binding; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Contains a lipoprotein signal peptide cleaved between the residues 21 and 22; localized in the outer membrane; Family membership; sulfatase 4053164 10976092 zobellia_3517 Zobellia galactanivorans sulfatase YP_004737934.1 4051065 D 63186 CDS YP_004737935.1 340619482 10976093 complement(4053192..4054952) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Family membership; sulfatase 4054952 10976093 zobellia_3518 Zobellia galactanivorans sulfatase YP_004737935.1 4053192 R 63186 CDS YP_004737936.1 340619483 10976094 complement(4055030..4056502) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 27; Possible lipoprotein signal peptide cleaved between the residues 27 and 28; Putatively localized in the outer membrane; Family membership; sulfatase 4056502 10976094 zobellia_3519 Zobellia galactanivorans sulfatase YP_004737936.1 4055030 R 63186 CDS YP_004737937.1 340619484 10976095 complement(4056566..4057987) 1 NC_015844.1 Sialate O-acetylesterase catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. Features a signal peptide cleaved between the residues 24 and 25. Localized in the periplasm.; High confidence in function and specificity; sialate O-acetylesterase 4057987 siaE2 10976095 siaE2 Zobellia galactanivorans sialate O-acetylesterase YP_004737937.1 4056566 R 63186 CDS YP_004737938.1 340619485 10978595 complement(4058019..4060367) 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 4060367 10978595 zobellia_3521 Zobellia galactanivorans hypothetical protein YP_004737938.1 4058019 R 63186 CDS YP_004737939.1 340619486 10976097 complement(4060483..4063023) 1 NC_015844.1 Alpha-L-rhamnosidase catalyzes the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides. It belongs to the family 78 of the glycoside hydrolases. Features an uncleaved signal peptide. Localized in the cytoplasmic membrane.; High confidence in function and specificity; alpha-L-rhamnosidase 4063023 rhaA 10976097 rhaA Zobellia galactanivorans alpha-L-rhamnosidase YP_004737939.1 4060483 R 63186 CDS YP_004737940.1 340619487 10978452 complement(4063091..4065691) 1 NC_015844.1 This enzyme is a modular protein consisting of a N-terminal module belonging to the family 6 of the carbohydrate esterases (CE6; 26-342), a central alpha-galactosidase domain belonging to family 27 of the glycoside hydrolases (GH27; 343-733) and a C-terminal domain of unknown function (734-866). Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides. The catalytic machinery is a Ser-His-Asp triad. Alpha-galactosidase catalyzes the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides; Signal peptide cleaved between residues 25 and 26; Localized in the periplasm; Specificity unclear; carbohydrate esterase / alpha-galactosidase 4065691 10978452 zobellia_3523 Zobellia galactanivorans carbohydrate esterase / alpha-galactosidase YP_004737940.1 4063091 R 63186 CDS YP_004737941.1 340619488 10976098 complement(4065716..4068283) 1 NC_015844.1 Modular protein with a N-terminal acetylesterase (lipase-GDSL family), which includes families 3 and 12 of the carbohydrate esterases (CE3 and CE12), a central alpha/beta hydrolase fold domain and a C-terminal GDSL_hydrolase fold domain; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Specificity unclear; lipase-GDSL family acetylesterase 4068283 10976098 zobellia_3524 Zobellia galactanivorans lipase-GDSL family acetylesterase YP_004737941.1 4065716 R 63186 CDS YP_004737942.1 340619489 10976099 complement(4068322..4069773) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Family membership; sulfatase 4069773 10976099 zobellia_3525 Zobellia galactanivorans sulfatase YP_004737942.1 4068322 R 63186 CDS YP_004737943.1 340619490 10976100 complement(4069879..4071426) 1 NC_015844.1 Iduronate-2-sulfatase, called also chondroitinsulfatase is involved in the glycosaminoglycan degradation. It hydrolyzes the 2-sulfate groups from non-reducing-terminal iduronic acid residues in dermatan sulfate, heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 7; Lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane or/and cytoplasmic membrane; High confidence in function and specificity; iduronate-2-sulfatase 4071426 idsA4 10976100 idsA4 Zobellia galactanivorans iduronate-2-sulfatase YP_004737943.1 4069879 R 63186 CDS YP_004737944.1 340619491 10978027 4071820..4073427 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 20; Contains a lipoprotein signal peptide cleaved between the residues 23 and 24; Localized in the outer membrane; Family membership; sulfatase 4073427 10978027 zobellia_3527 Zobellia galactanivorans sulfatase YP_004737944.1 4071820 D 63186 CDS YP_004737945.1 340619492 10976101 4073672..4074241 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 4074241 10976101 zobellia_3528 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004737945.1 4073672 D 63186 CDS YP_004737946.1 340619494 10976102 complement(4074245..4074445) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4074445 10976102 zobellia_3530 Zobellia galactanivorans hypothetical protein YP_004737946.1 4074245 R 63186 CDS YP_004737947.1 340619493 10976105 4074445..4075506 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 4075506 10976105 zobellia_3529 Zobellia galactanivorans anti-sigma factor YP_004737947.1 4074445 D 63186 CDS YP_004737948.1 340619495 10976103 4075722..4079027 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain (49-100)) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (111-183), and a Plug module (199-309) acting as the channel gate; The signal peptide is cleaved between the residue 22 and 23; Family membership; TonB-dependent transducer 4079027 10976103 zobellia_3531 Zobellia galactanivorans TonB-dependent transducer YP_004737948.1 4075722 D 63186 CDS YP_004737949.1 340619496 10976106 4079038..4080711 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 4080711 10976106 zobellia_3532 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737949.1 4079038 D 63186 CDS YP_004737950.1 340619497 10976107 4080886..4083378 1 NC_015844.1 Enzyme belonging to the family 2 of glycoside hydrolases (GH2) which catalyzes the hydrolysis of the beta-1,4 linkage at the terminal non-reducing, releasing a beta-D-galactose residue from beta-D-galactosides; Putative signal peptide cleaved between residues 19 and 20; Possibly localized in the periplasmic space; High confidence in function and specificity; beta-galactosidase 4083378 bgaC 10976107 bgaC Zobellia galactanivorans beta-galactosidase YP_004737950.1 4080886 D 63186 CDS YP_004737951.1 340619498 10977595 4083428..4085806 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 95 of the glycoside hydrolases (GH95); Signal peptide cleaved between residues the residues 25 and 26; Localized in the periplsamic space; High confidence in function and specificity; alpha-L-fucosidase 4085806 afcA4 10977595 afcA4 Zobellia galactanivorans alpha-L-fucosidase YP_004737951.1 4083428 D 63186 CDS YP_004737952.1 340619499 10977479 4085806..4088235 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside, Belongs to the family 95 of the glycoside hydrolases (GH95); Signal peptide cleaved between residues 25 and 26; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 4088235 afcA5 10977479 afcA5 Zobellia galactanivorans alpha-L-fucosidase YP_004737952.1 4085806 D 63186 CDS YP_004737953.1 340619500 10977480 complement(4088370..4089881) 1 NC_015844.1 Alkaline phosphatase is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH; Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymic activity; Localized in the cytoplasm; High confidence in function and specificity; alkaline phosphatase 4089881 phoD1 10977480 phoD1 Zobellia galactanivorans alkaline phosphatase YP_004737953.1 4088370 R 63186 CDS YP_004737954.1 340619501 10978347 complement(4089928..4091496) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 23; Signal peptide of lipoprotein cleaved between the residues 22 and 23, Localized in the outer membrane; Family membership; sulfatase 4091496 10978347 zobellia_3537 Zobellia galactanivorans sulfatase YP_004737954.1 4089928 R 63186 CDS YP_004737955.1 340619502 10976108 complement(4091507..4093120) 1 NC_015844.1 Sodium/substrate symporter actively transports glucose into cells by Na+ cotransport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains fourteen transmembrane helices; Localized in the cytoplasmic membrane.; High confidence in function and specificity; sodium/glucose symporter 4093120 10976108 zobellia_3538 Zobellia galactanivorans sodium/glucose symporter YP_004737955.1 4091507 R 63186 CDS YP_004737956.1 340619503 10976109 complement(4093122..4094084) 1 NC_015844.1 Oxydoreductase NADPH dependent; Belongs to the aldo/keto reductase 2 family; Localized in the cytoplasm; Family membership; aldo/keto reductase 4094084 10976109 zobellia_3539 Zobellia galactanivorans aldo/keto reductase YP_004737956.1 4093122 R 63186 CDS YP_004737957.1 340619504 10976110 complement(4094157..4096610) 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 95 of the glycoside hydrolases (GH95); Signal peptide cleaved between residues 25 and 26; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 4096610 afcA6 10976110 afcA6 Zobellia galactanivorans alpha-L-fucosidase YP_004737957.1 4094157 R 63186 CDS YP_004737958.1 340619505 10977481 complement(4096849..4098300) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 4098300 10977481 zobellia_3541 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737958.1 4096849 R 63186 CDS YP_004737959.1 340619506 10976112 complement(4098343..4101585) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (32-105) and the Plug module (122-247) acting as a channel gate; The signal peptide is cleaved between the residues 26 and 27; Family membership; TonB-dependent Receptor 4101585 10976112 zobellia_3542 Zobellia galactanivorans TonB-dependent Receptor YP_004737959.1 4098343 R 63186 CDS YP_004737960.1 340619508 10976113 complement(4101801..4103384) 1 NC_015844.1 L-serine dehydratase is involved in the gluconeogenesis pathway. It catalyzes the deamination of serine to form pyruvate. It is activated by a post-translational modification via a system involving at least three gene products. There is considerable evidence for a free-radical activation mechanism; Binds a 4Fe-4S cluster as a cofactor; Localized in the cytoplasm; High confidence in function and specificity; L-serine dehydratase 4103384 sdaA1 10976113 sdaA1 Zobellia galactanivorans L-serine dehydratase YP_004737960.1 4101801 R 63186 CDS YP_004737961.1 340619507 10978569 4103359..4103463 1 NC_015844.1 Hypothetical protein; hypothetical protein 4103463 10978569 zobellia_3543 Zobellia galactanivorans hypothetical protein YP_004737961.1 4103359 D 63186 CDS YP_004737962.1 340619509 10976114 4103594..4104466 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 4104466 10976114 zobellia_3545 Zobellia galactanivorans AraC family transcriptional regulator YP_004737962.1 4103594 D 63186 CDS YP_004737963.1 340619510 10976115 4104532..4105395 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 4105395 10976115 zobellia_3546 Zobellia galactanivorans AraC family transcriptional regulator YP_004737963.1 4104532 D 63186 CDS YP_004737964.1 340619511 10976116 4105640..4107877 1 NC_015844.1 Dipeptidyl-peptidase IV releases an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline. Belongs to the family S9 of the serine peptidases. The active site residues are in the order Ser, Asp, His in the sequence. The motif around the active site serine is G W S (Y/F) G G. DppA displays a two domain architecture, with a N-terminal eight-bladed beta-propeller and a C-terminal S9 peptidase domain. Features a signal peptide cleaved between the residues 21 and 22. Localized in the periplasm.; High confidence in function and specificity; dipeptidyl peptidase 4107877 dppA2 10976116 dppA2 Zobellia galactanivorans dipeptidyl peptidase YP_004737964.1 4105640 D 63186 CDS YP_004737965.1 340619512 10977760 4108033..4109616 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 25; Contains an N-terminal transmembrane segment; Contains a N- terminal transmembrane segment; Localized in the cytoplasmic membrane; Family membership; sulfatase 4109616 10977760 zobellia_3548 Zobellia galactanivorans sulfatase YP_004737965.1 4108033 D 63186 CDS YP_004737966.1 340619513 10976117 4109746..4111149 1 NC_015844.1 Aminopeptidase catalyzes the hydrolysis of N-terminal amino-acid residues from oligopeptides or polypeptides. Belongs to the family M24 of the metallopeptidases. Requires two co-catalytic ions of manganese. Localized in the cytoplasm.; Specificity unclear; aminopeptidase 4111149 10976117 zobellia_3549 Zobellia galactanivorans aminopeptidase YP_004737966.1 4109746 D 63186 CDS YP_004737967.1 340619514 10976118 complement(4111162..4111311) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4111311 10976118 zobellia_3550 Zobellia galactanivorans hypothetical protein YP_004737967.1 4111162 R 63186 CDS YP_004737968.1 340619515 10976120 complement(4111379..4111927) 1 NC_015844.1 Protein conserved in the bacteria of the chlorobiaceae family; Signal peptide cleaved between the residues 21 and 22; Probably localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4111927 10976120 zobellia_3551 Zobellia galactanivorans periplasmic protein YP_004737968.1 4111379 R 63186 CDS YP_004737969.1 340619516 10976121 complement(4112110..4112547) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity that acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership; two-component system-response regulator, receiver domain 4112547 10976121 zobellia_3552 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004737969.1 4112110 R 63186 CDS YP_004737970.1 340619517 10976122 4113178..4114581 1 NC_015844.1 Protein that consists of two domains of unknown function DUF1080; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 28 and 29; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4114581 10976122 zobellia_3553 Zobellia galactanivorans lipoprotein YP_004737970.1 4113178 D 63186 CDS YP_004737971.1 340619518 10976123 4114584..4115912 1 NC_015844.1 NAD(P)-dependent dehydrogenase. Belongs to the Rossmann fold family. Features a twin-arginine translocation signal peptide.; Specificity unclear; NAD(P)-dependent dehydrogenase 4115912 10976123 zobellia_3554 Zobellia galactanivorans NAD(P)-dependent dehydrogenase YP_004737971.1 4114584 D 63186 CDS YP_004737972.1 340619519 10976124 4115958..4116149 1 NC_015844.1 Hypothetical protein; hypothetical protein 4116149 10976124 zobellia_3555 Zobellia galactanivorans hypothetical protein YP_004737972.1 4115958 D 63186 CDS YP_004737973.1 340619520 10976125 complement(4116146..4117213) 1 NC_015844.1 LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of catabolic, metabolic and transport operons; Contains a N-terminal LacI-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a C-terminal domain involved in the binding of inducers; Localized in the cytoplasm; Family membership; LacI-type transcriptional regulator 4117213 10976125 zobellia_3556 Zobellia galactanivorans LacI-type transcriptional regulator YP_004737973.1 4116146 R 63186 CDS YP_004737974.1 340619521 10976126 complement(4117444..4117905) 1 NC_015844.1 Possible presence of an N-terminal transmembrane segment that would localize the protein in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 4117905 10976126 zobellia_3557 Zobellia galactanivorans hypothetical protein YP_004737974.1 4117444 R 63186 CDS YP_004737975.1 340619522 10976127 complement(4118058..4118402) 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 4118402 10976127 zobellia_3558 Zobellia galactanivorans hypothetical protein YP_004737975.1 4118058 R 63186 CDS YP_004737976.1 340619523 10976128 complement(4118428..4120569) 1 NC_015844.1 This enzyme is a mono-functional haem-containing catalase that acts as an antioxidant enzyme catalyzing the conversion of hydrogen peroxide to water and molecular oxygen, serving to protect cells from its toxic effects. Localized in the cytoplasm.; High confidence in function and specificity; catalase 4120569 katA2 10976128 katA2 Zobellia galactanivorans catalase YP_004737976.1 4118428 R 63186 CDS YP_004737977.1 340619524 10978048 complement(4120627..4121040) 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 4121040 10978048 zobellia_3560 Zobellia galactanivorans hypothetical protein YP_004737977.1 4120627 R 63186 CDS YP_004737978.1 340619525 10976130 4121121..4121243 1 NC_015844.1 Hypothetical protein; hypothetical protein 4121243 10976130 zobellia_3561 Zobellia galactanivorans hypothetical protein YP_004737978.1 4121121 D 63186 CDS YP_004737979.1 340619526 10976131 4121343..4121747 1 NC_015844.1 Protein that consists of a glyoxalase/bleomycin resistance protein/dioxygenase domain. It also consists of a demethylubiquinone-9 3-methyltransferase domain that is superimposed on the precedent domain; localized in the cytoplasm; hypothetical protein 4121747 10976131 zobellia_3562 Zobellia galactanivorans hypothetical protein YP_004737979.1 4121343 D 63186 CDS YP_004737980.1 340619527 10976132 4121780..4122301 1 NC_015844.1 Contains three N-terminal transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4122301 10976132 zobellia_3563 Zobellia galactanivorans membrane protein YP_004737980.1 4121780 D 63186 CDS YP_004737981.1 340619528 10976133 4122523..4122744 1 NC_015844.1 Hypothetical protein; hypothetical protein 4122744 10976133 zobellia_3564 Zobellia galactanivorans hypothetical protein YP_004737981.1 4122523 D 63186 CDS YP_004737982.1 340619529 10976134 4122865..4123314 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 4123314 10976134 zobellia_3565 Zobellia galactanivorans hypothetical protein YP_004737982.1 4122865 D 63186 CDS YP_004737983.1 340619530 10976135 complement(4123376..4124224) 1 NC_015844.1 The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels. The active site His and Ser residues are located at the exterior of the beta-barrel, at the outer leaflet side of the membrane; Localized in the outer membrane; High confidence in function and specificity; phospholipase A1 4124224 pldA 10976135 pldA Zobellia galactanivorans phospholipase A1 YP_004737983.1 4123376 R 63186 CDS YP_004737984.1 340619531 10978353 complement(4124370..4125998) 1 NC_015844.1 Contains four N-terminal tetratricopeptide repeats (TPR) involved in protein-protein interactions and the assembly of multiprotein complexes, and a C-terminal LuxR-type HTH domain. These two domains are separated by a transmembrane segement; This Protein could interact with the DNA (transcriptional control or transcription factor); localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4125998 10978353 zobellia_3567 Zobellia galactanivorans membrane protein YP_004737984.1 4124370 R 63186 CDS YP_004737985.1 340619532 10976136 4126495..4128018 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide cleaved between the residue 19 and 20; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 4128018 fucA4 10976136 fucA4 Zobellia galactanivorans alpha-L-fucosidase YP_004737985.1 4126495 D 63186 CDS YP_004737986.1 340619533 10977861 complement(4128398..4128586) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4128586 10977861 zobellia_3569 Zobellia galactanivorans hypothetical protein YP_004737986.1 4128398 R 63186 CDS YP_004737987.1 340619534 10976137 4128951..4132034 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules (here, possibly oligoagaroses) that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (32-104) and the Plug module (120-227) acting as a channel gate; The signal peptide is cleaved between the residues 28 and 29; Family membership; TonB-dependent Receptor 4132034 10976137 zobellia_3570 Zobellia galactanivorans TonB-dependent Receptor YP_004737987.1 4128951 D 63186 CDS YP_004737988.1 340619535 10976139 4132091..4133857 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 21 and 22; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 4133857 10976139 zobellia_3571 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737988.1 4132091 D 63186 CDS YP_004737989.1 340619536 10976140 4133892..4135535 1 NC_015844.1 Conserved lipoprotein containing a N-terminal domain of unknown function and a C-terminal Carbohydrate Binding Module of family 22 (CBM22); Signal peptide cleaved between the residues 28 and 29; localized in the cytoplasmic membrane; Hypothetical protein; lipoprotein 4135535 10976140 zobellia_3572 Zobellia galactanivorans lipoprotein YP_004737989.1 4133892 D 63186 CDS YP_004737990.1 340619537 10976141 4135622..4136683 1 NC_015844.1 The beta-agarase B hydrolyses the 1,4-beta-D-galactosidic linkages in agarose, giving the tetramer and the dimer as the predominant products; Acts on agarose as a homodimer; Belongs to the family 16 of glycoside hydrolases (GH16); Signal peptide of lipoprotein cleaved between the residues 17 and 18; Localized in the outer membrane; High confidence in function and specificity; beta-agarase B 4136683 agaB 10976141 agaB Zobellia galactanivorans beta-agarase B YP_004737990.1 4135622 D 63186 CDS YP_004737991.1 340619538 10977484 4136952..4137857 1 NC_015844.1 CbpA is a DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of dnaJ; displays overlapping activities with dnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by dnaK; Contains an N-terminal J domain; Localized in the cytoplasm; High confidence in function and specificity; Co-chaperone protein CbpA 4137857 cbpA 10977484 cbpA Zobellia galactanivorans Co-chaperone protein CbpA YP_004737991.1 4136952 D 63186 CDS YP_004737992.1 340619539 10977625 4137862..4138152 1 NC_015844.1 Possibly localized in the cytoplasm; hypothetical protein 4138152 10977625 zobellia_3575 Zobellia galactanivorans hypothetical protein YP_004737992.1 4137862 D 63186 CDS YP_004737993.1 340619540 10976142 complement(4138189..4138581) 1 NC_015844.1 The AraC-type HTH domain found in the sequence, encompasses more than 75% of the length sequence; Family membership; AraC family transcriptional regulator 4138581 10976142 zobellia_3576 Zobellia galactanivorans AraC family transcriptional regulator YP_004737993.1 4138189 R 63186 CDS YP_004737994.1 340619541 10976143 4138933..4140801 1 NC_015844.1 The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Localized in the cytoplasm; High confidence in function and specificity; N-sulfoglucosamine sulfohydrolase 4140801 sgsA7 10976143 sgsA7 Zobellia galactanivorans N-sulfoglucosamine sulfohydrolase YP_004737994.1 4138933 D 63186 CDS YP_004737995.1 340619542 10978592 4141037..4142881 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Family membership; sulfatase 4142881 10978592 zobellia_3578 Zobellia galactanivorans sulfatase YP_004737995.1 4141037 D 63186 CDS YP_004737996.1 340619543 10976144 complement(4143075..4143194) 1 NC_015844.1 Peptide Putatively localized in the cytoplasm; hypothetical protein 4143194 10976144 zobellia_3579 Zobellia galactanivorans hypothetical protein YP_004737996.1 4143075 R 63186 CDS YP_004737997.1 340619544 10976145 complement(4143222..4144973) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 24 and 25; Putatively localized in the outer membrane but the determination of the membrane identity for the protein localization is not clear; Family membership; SusD/RagB family lipoprotein 4144973 10976145 zobellia_3580 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004737997.1 4143222 R 63186 CDS YP_004737998.1 340619545 10976147 complement(4144984..4148214) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (58-131) and the Plug module (147-263) acting as a channel gate; The signal peptide is cleaved between the residues 38 and 39; Family membership; TonB-dependent Receptor 4148214 10976147 zobellia_3581 Zobellia galactanivorans TonB-dependent Receptor YP_004737998.1 4144984 R 63186 CDS YP_004737999.1 340619546 10976148 4148507..4148599 1 NC_015844.1 Hypothetical protein; hypothetical protein 4148599 10976148 zobellia_3582 Zobellia galactanivorans hypothetical protein YP_004737999.1 4148507 D 63186 CDS YP_004738000.1 340619547 10976149 complement(4148740..4149147) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity which acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership; two-component system-response regulator, receiver domain 4149147 10976149 zobellia_3583 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004738000.1 4148740 R 63186 CDS YP_004738001.1 340619548 10976150 complement(4149157..4151742) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two N-terminal PAS/PAC domains involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 4151742 10976150 zobellia_3584 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738001.1 4149157 R 63186 CDS YP_004738002.1 340619549 10976151 complement(4151860..4151955) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4151955 10976151 zobellia_3585 Zobellia galactanivorans hypothetical protein YP_004738002.1 4151860 R 63186 CDS YP_004738003.1 340619550 10976152 complement(4151994..4152116) 1 NC_015844.1 Protein that consists of an Helix-turn-helix, AraC type; This motif is found in various transcriptional regulators and situated towards the C-terminus in the third quarter of most of the sequences; Function unclear; AraC family transcriptional regulator 4152116 10976152 zobellia_3586 Zobellia galactanivorans AraC family transcriptional regulator YP_004738003.1 4151994 R 63186 CDS YP_004738004.1 340619551 10976153 4152400..4153488 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Possibly localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 4153488 10976153 zobellia_3587 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738004.1 4152400 D 63186 CDS YP_004738005.1 340619552 10976154 4153491..4154819 1 NC_015844.1 These response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes, activating the expression of genes from promoters recognized by core RNA polymerase associated with the alternative sigma-54 factor. These proteins consist of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, a motif that interacts with the sigma 54 factor and a C-terminal Fis-type HTH motif; Family membership; sigma-54 dependent two-component system-response regulator 4154819 10976154 zobellia_3588 Zobellia galactanivorans sigma-54 dependent two-component system-response regulator YP_004738005.1 4153491 D 63186 CDS YP_004738006.1 340619553 10976155 4154959..4155447 1 NC_015844.1 Conserved protein belonging to the GreA family of the transcription elongation factors. Localized in the cytoplasm.; Specificity unclear; GreA-like transcription elongation factor 4155447 10976155 zobellia_3589 Zobellia galactanivorans GreA-like transcription elongation factor YP_004738006.1 4154959 D 63186 CDS YP_004738007.1 340619554 10976156 4155482..4155844 1 NC_015844.1 Contains a signal peptide cleaved between the residues 17 and 18; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4155844 10976156 zobellia_3590 Zobellia galactanivorans periplasmic protein YP_004738007.1 4155482 D 63186 CDS YP_004738008.1 340619555 10976158 4156163..4157455 1 NC_015844.1 Glutamate dehydrogenase catalyzes the NAD- and/or NADP-dependent reversible deamination of L-glutamate into alpha-ketoglutarate. It is involved with either ammonia assimilation or glutamate catabolism. Forms a homohexamer and binds one NAD(P) cofactor by subunit. Localized in the cytoplasm.; High confidence in function and specificity; glutamate dehydrogenase 4157455 gdhA2 10976158 gdhA2 Zobellia galactanivorans glutamate dehydrogenase YP_004738008.1 4156163 D 63186 CDS YP_004738009.1 340619556 10977888 4157467..4157883 1 NC_015844.1 Rnk regulates the level of nucleoside diphosphate kinase. It belongs to the GreA family of elongation transcription factor; Localized in the cytoplasm; High confidence in function and specificity; regulator of nucleoside diphosphate kinase 4157883 rnkA 10977888 rnkA Zobellia galactanivorans regulator of nucleoside diphosphate kinase YP_004738009.1 4157467 D 63186 CDS YP_004738010.1 340619557 10978483 complement(4158067..4159218) 1 NC_015844.1 Possible 3-carboxymuconate cyclase, which converts by isomerisation the 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate to 3-carboxy-cis,cis-muconate; Contains a signal peptide of lipoprotein cleaved between the residues 19 and 20; Belongs to the cycloisomerase 2 family; Localized in the cytoplasmic membrane; Family membership; 3-carboxymuconate cyclase-like protein 4159218 10978483 zobellia_3593 Zobellia galactanivorans 3-carboxymuconate cyclase-like protein YP_004738010.1 4158067 R 63186 CDS YP_004738011.1 340619558 10976159 complement(4159237..4161180) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 4161180 10976159 zobellia_3594 Zobellia galactanivorans hypothetical protein YP_004738011.1 4159237 R 63186 CDS YP_004738012.1 340619559 10976160 complement(4161211..4162698) 1 NC_015844.1 Mucin-desulfating sulfatases hydrolyse the sulfate groups from oligosaccharides present in mucins (heavily glycosylated proteins). In the mucins, the main sulfated sugars are N-acetyl-D-glucosamine-6-sulfate, galactose-6-sulfate and galactose-3-sulfate; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 11; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Specificity unclear; mucin-desulfating sulfatase 4162698 mdsA5 10976160 mdsA5 Zobellia galactanivorans mucin-desulfating sulfatase YP_004738012.1 4161211 R 63186 CDS YP_004738013.1 340619560 10978136 complement(4162747..4164198) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 14; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Family membership; sulfatase 4164198 10978136 zobellia_3596 Zobellia galactanivorans sulfatase YP_004738013.1 4162747 R 63186 CDS YP_004738014.1 340619561 10976161 complement(4164380..4165681) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 22 and 23; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4165681 10976161 zobellia_3597 Zobellia galactanivorans lipoprotein YP_004738014.1 4164380 R 63186 CDS YP_004738015.1 340619562 10976162 complement(4165727..4166881) 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved betweenthe residues 18 and 19; Possibly localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4166881 10976162 zobellia_3598 Zobellia galactanivorans lipoprotein YP_004738015.1 4165727 R 63186 CDS YP_004738016.1 340619563 10976163 complement(4166957..4170016) 1 NC_015844.1 Modular enzyme with a N-terminal beta-galactosidase domain (belongs to the family 2 of glycoside hydrolases, TIM alpha/beta barrel fold) and two C-terminal fibronectin type III domain (FN3); Seems to have a signal peptide cleaved between the residues 20 and 21; Putatively localized in the periplasmic space; Family membership; glycoside hydrolase 4170016 10976163 zobellia_3599 Zobellia galactanivorans glycoside hydrolase YP_004738016.1 4166957 R 63186 CDS YP_004738017.1 340619564 10976164 complement(4170028..4171467) 1 NC_015844.1 The N-sulfoglucosamine sulfohydrolase, called also Sulfoglucosamine sulfamidase is involved in the glycosaminoglycan degradation. It hydrolyzes the N-sulfate groups from the D-glucosamine-N-sulfate-6-O-sulfate residues in heparan sulfate and heparin; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 8; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; High confidence in function and specificity; N-sulfoglucosamine sulfohydrolase 4171467 sgsA8 10976164 sgsA8 Zobellia galactanivorans N-sulfoglucosamine sulfohydrolase YP_004738017.1 4170028 R 63186 CDS YP_004738018.1 340619565 10978593 complement(4171506..4173797) 1 NC_015844.1 The family 2 of glycoside Hydrolase (GH2, TIM alpha/beta barrel fold) contains the activities beta-galactosidase, beta-mannosidase, beta-glucuronidase and exo-beta-glucosaminidase; Signal peptide of lipoprotein cleaved between the residues 17 and 18; Localized in the outer membrane; Family membership; glycoside hydrolase 4173797 10978593 zobellia_3601 Zobellia galactanivorans glycoside hydrolase YP_004738018.1 4171506 R 63186 CDS YP_004738019.1 340619566 10976167 complement(4173807..4175759) 1 NC_015844.1 Alpha-glucosidases catalyse the hydrolysis of terminal, non-reducing 1,4-linked alpha-D-glucose residues with release of alpha-D-glucose. Involved in carbohydrate metabolism, notably in starch degradation; Belongs to the family 97 of glycoside hydrolases (GH97); Lipoprotein signal peptide cleaved between the residues 20 and 21; Probably localized in the outer membrane; High confidence in function and specificity; alpha-glucosidase 4175759 10976167 zobellia_3602 Zobellia galactanivorans alpha-glucosidase YP_004738019.1 4173807 R 63186 CDS YP_004738020.1 340619567 10976168 complement(4175776..4176660) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4176660 10976168 zobellia_3603 Zobellia galactanivorans periplasmic protein YP_004738020.1 4175776 R 63186 CDS YP_004738021.1 340619568 10976169 complement(4176677..4178968) 1 NC_015844.1 Contains a N-terminal flavoprotein domain (20 to 426); Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Localized in the cytoplasm; Family membership; putative FAD dependent oxidoreductase 4178968 10976169 zobellia_3604 Zobellia galactanivorans putative FAD dependent oxidoreductase YP_004738021.1 4176677 R 63186 CDS YP_004738022.1 340619569 10976170 complement(4179034..4180692) 1 NC_015844.1 Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains 15 transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sodium/solute symporter 4180692 10976170 zobellia_3605 Zobellia galactanivorans sodium/solute symporter YP_004738022.1 4179034 R 63186 CDS YP_004738023.1 340619570 10976171 complement(4180803..4182611) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 4182611 10976171 zobellia_3606 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004738023.1 4180803 R 63186 CDS YP_004738024.1 340619571 10976172 complement(4182630..4185737) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (22-95) and the Plug module (111-220) acting as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 4185737 10976172 zobellia_3607 Zobellia galactanivorans TonB-dependent Receptor YP_004738024.1 4182630 R 63186 CDS YP_004738025.1 340619572 10976173 complement(4186000..4186110) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4186110 10976173 zobellia_3608 Zobellia galactanivorans hypothetical protein YP_004738025.1 4186000 R 63186 CDS YP_004738026.1 340619573 10976174 4186124..4187140 1 NC_015844.1 Transcriptional regulator involved in the repression and/or the positive regulation of genes encoding for enzymes; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcriptional regulators, involved in the binding of the protein to the operator sequences in the DNA. At the C-terminus there is an effector- binding/oligomerisation domain; Localized in the cytoplasm; Family membership; GntR family transcriptional regulator 4187140 10976174 zobellia_3609 Zobellia galactanivorans GntR family transcriptional regulator YP_004738026.1 4186124 D 63186 CDS YP_004738027.1 340619574 10976175 complement(4187149..4188591) 1 NC_015844.1 CstA is induced during carbon starvation and is positively regulated by the cyclic AMP (cAMP) and cAMP receptor protein complex. It is involved in peptide utilization; Contains 13 transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; carbon starvation protein A 4188591 cstA 10976175 cstA Zobellia galactanivorans carbon starvation protein A YP_004738027.1 4187149 R 63186 CDS YP_004738028.1 340619575 10977690 complement(4188615..4189733) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4189733 10977690 zobellia_3611 Zobellia galactanivorans periplasmic protein YP_004738028.1 4188615 R 63186 CDS YP_004738029.1 340619576 10976177 complement(4189730..4191523) 1 NC_015844.1 Contains a C-terminal flavoprotein domain (206 to 593); Belongs to the FAD/NAD(P)-binding Rossmann fold Superfamily, pyridine nucleotide-disulfide oxidoreductase family; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Family membership; putative FAD dependent oxidoreductase 4191523 10976177 zobellia_3612 Zobellia galactanivorans putative FAD dependent oxidoreductase YP_004738029.1 4189730 R 63186 CDS YP_004738030.1 340619577 10976178 complement(4191767..4194682) 1 NC_015844.1 Enzyme belonging to the family 2 of glycoside hydrolases (GH2) which catalyzes the hydrolysis of the beta-1,4 linkage at the terminal non-reducing of beta-D-galactosides, releasing a beta-D-galactose residue; Possesses a putative C-terminal carbohydrate module (CBM6); Signal peptide cleaved between residues 19 and 20; Localized in the periplasmic space; High confidence in function and specificity; beta-galactosidase 4194682 bgaA 10976178 bgaA Zobellia galactanivorans beta-galactosidase YP_004738030.1 4191767 R 63186 CDS YP_004738031.1 340619578 10977593 complement(4194718..4196979) 1 NC_015844.1 Large conserved protein containing a C-terminal cytochrome c. Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes; Contains a putative lipoprotein signal peptide cleaved between the residues 31 and 32; Possibly localized in the outer membrane; Family membership; cytochrome c-containing protein 4196979 10977593 zobellia_3614 Zobellia galactanivorans cytochrome c-containing protein YP_004738031.1 4194718 R 63186 CDS YP_004738032.1 340619579 10976179 complement(4197022..4198266) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4198266 10976179 zobellia_3615 Zobellia galactanivorans periplasmic protein YP_004738032.1 4197022 R 63186 CDS YP_004738033.1 340619580 10976180 complement(4198287..4199708) 1 NC_015844.1 Modular protein that consists of an N-terminal alpha-L-fucosidase module belonging to the family 29 of glycoside hydrolases (GH29), responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside and a C-terminal domain that could be involved in the binding to specific ligands such as carbohydrate or lipids substrates; Signal peptide cleaved between the residue 19 and 20; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 4199708 alfA6 10976180 alfA6 Zobellia galactanivorans alpha-L-fucosidase YP_004738033.1 4198287 R 63186 CDS YP_004738034.1 340619581 10977499 complement(4199717..4201096) 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide cleaved between the residue 23 and 24; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 4201096 fucA5 10977499 fucA5 Zobellia galactanivorans alpha-L-fucosidase YP_004738034.1 4199717 R 63186 CDS YP_004738035.1 340619582 10977862 complement(4201140..4202627) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 15; Signal petide cleaved between the residues 25 and 26; Localized in the periplasmic space; Family membership; sulfatase 4202627 10977862 zobellia_3618 Zobellia galactanivorans sulfatase YP_004738035.1 4201140 R 63186 CDS YP_004738036.1 340619583 10976181 complement(4202686..4202784) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4202784 10976181 zobellia_3619 Zobellia galactanivorans hypothetical protein YP_004738036.1 4202686 R 63186 CDS YP_004738037.1 340619584 10976182 complement(4202848..4204521) 1 NC_015844.1 This protein likely adopts a right handed parallel beta-helix fold; Signal peptide cleaved between the residues 25 and 26; Localized in the periplasmic space; hypothetical protein 4204521 10976182 zobellia_3620 Zobellia galactanivorans hypothetical protein YP_004738037.1 4202848 R 63186 CDS YP_004738038.1 340619585 10976184 complement(4204702..4207182) 1 NC_015844.1 This conserved protein contains two N-terminal type-III fibronectin domains and a C-terminal domain of unknown function; Signal peptide cleaved between the residues 33 and 34; Localized in the periplasmic space; Family membership; fibronectin type-III repeat-containing protein 4207182 10976184 zobellia_3621 Zobellia galactanivorans fibronectin type-III repeat-containing protein YP_004738038.1 4204702 R 63186 CDS YP_004738039.1 340619586 10976185 complement(4207229..4208761) 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide cleaved between the residue 27 and 28; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 4208761 fucA6 10976185 fucA6 Zobellia galactanivorans alpha-L-fucosidase YP_004738039.1 4207229 R 63186 CDS YP_004738040.1 340619587 10977863 complement(4208758..4210416) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4210416 10977863 zobellia_3623 Zobellia galactanivorans periplasmic protein YP_004738040.1 4208758 R 63186 CDS YP_004738041.1 340619588 10976186 complement(4210437..4213091) 1 NC_015844.1 This protein displays distant similarity with glycoside hydrolases of the family 74 (GH74). These proteins consist of a tandem repeat of two similar domains, which are both folded into seven-bladed beta- propeller structures. But the two conserved catalytic aspartatic residues are substituted here by two asparagine residues. Features a signal peptide cleaved between the residues 19 and 20.; hypothetical protein 4213091 10976186 zobellia_3624 Zobellia galactanivorans hypothetical protein YP_004738041.1 4210437 R 63186 CDS YP_004738042.1 340619589 10976187 complement(4213092..4213916) 1 NC_015844.1 Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides; Belongs to the family 4 of carbohydrate esterases (CE4). These proteins fold into a 7-stranded beta/alpha barrel; Signal peptide cleaved between residues 20 and 21; Localized in the periplasmic space; Specificity unclear; carbohydrate esterase 4213916 10976187 zobellia_3625 Zobellia galactanivorans carbohydrate esterase YP_004738042.1 4213092 R 63186 CDS YP_004738043.1 340619590 10976188 complement(4213920..4214918) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4214918 10976188 zobellia_3626 Zobellia galactanivorans periplasmic protein YP_004738043.1 4213920 R 63186 CDS YP_004738044.1 340619591 10976189 complement(4214937..4217567) 1 NC_015844.1 This enzyme belongs to the family 74 of the glycoside hydrolases. These proteins consist of a tandem repeat of two similar domains, which are both folded into seven-bladed beta-propeller structures. The conserved catalytic residues are Asp70 and Asp 549. Features a signal peptide cleaved between the residues 24 and 25.; Specificity unclear; glycoside hydrolase 4217567 10976189 zobellia_3627 Zobellia galactanivorans glycoside hydrolase YP_004738044.1 4214937 R 63186 CDS YP_004738045.1 340619592 10976190 complement(4217601..4218884) 1 NC_015844.1 The beta-porphyranases hydrolyse the 1,4-beta-D-galactosidic linkages in porphyrans; Contains a C-terminal domain of unknown function; Belongs to the family 16 of glycoside hydrolases (GH16); Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; High confidence in function and specificity; beta-porphyranase D 4218884 porD 10976190 porD Zobellia galactanivorans beta-porphyranase D YP_004738045.1 4217601 R 63186 CDS YP_004738046.1 340619593 10978364 complement(4218897..4220513) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 30; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Family membership; sulfatase 4220513 10978364 zobellia_3629 Zobellia galactanivorans sulfatase YP_004738046.1 4218897 R 63186 CDS YP_004738047.1 340619594 10976191 complement(4220551..4222119) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 28; Signal peptide cleaved between the residues 25 and 26; Localized in the periplasmic space; Family membership; sulfatase 4222119 10976191 zobellia_3630 Zobellia galactanivorans sulfatase YP_004738047.1 4220551 R 63186 CDS YP_004738048.1 340619595 10976193 complement(4222124..4223512) 1 NC_015844.1 The polygalacturonases catalyze the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans; The tertiary structures show a stack of parallel beta strands that are coiled into a large helix; Belongs to the family 28 of glycoside hydrolases (GH28); Signal peptide of lipoprotein cleaved between the residues 19 and 20; Localized in the outer membrane; Specificity unclear; polygalacturonase 4223512 10976193 zobellia_3631 Zobellia galactanivorans polygalacturonase YP_004738048.1 4222124 R 63186 CDS YP_004738049.1 340619596 10976194 complement(4223514..4224917) 1 NC_015844.1 The polygalacturonases catalyze the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans; The tertiary structures show a stack of parallel beta strands that are coiled into a large helix; Belongs to the family 28 of glycoside hydrolases (GH28); Signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane and possibly secreted; Specificity unclear; polygalacturonase 4224917 10976194 zobellia_3632 Zobellia galactanivorans polygalacturonase YP_004738049.1 4223514 R 63186 CDS YP_004738050.1 340619597 10976195 complement(4224923..4227400) 1 NC_015844.1 Enzyme belonging to the family 2 of glycoside hydrolases (GH2) which catalyzes the hydrolysis of the beta-1,4 linkage at the terminal non-reducing of beta-D-galactosides, releasing a beta-D-galactose residue; Signal peptide cleaved between residues 20 and 21; Localized in the periplasmic space; High confidence in function and specificity; beta-galactosidase 4227400 bgaB 10976195 bgaB Zobellia galactanivorans beta-galactosidase YP_004738050.1 4224923 R 63186 CDS YP_004738051.1 340619598 10977594 4227761..4229317 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide of lipoprotein cleaved between the residue 18 and 19; Localized in outer membrane; High confidence in function and specificity; alpha-L-fucosidase 4229317 fucA7 10977594 fucA7 Zobellia galactanivorans alpha-L-fucosidase YP_004738051.1 4227761 D 63186 CDS YP_004738052.1 340619599 10977864 complement(4229527..4231044) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 28; Putative lipoprotein with a signal peptide cleaved between the residues 15 and 16; Possibly localized in the outer membrane; Family membership; sulfatase 4231044 10977864 zobellia_3635 Zobellia galactanivorans sulfatase YP_004738052.1 4229527 R 63186 CDS YP_004738053.1 340619600 10976196 complement(4231212..4235453) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 4235453 10976196 zobellia_3636 Zobellia galactanivorans one-component system sensor protein YP_004738053.1 4231212 R 63186 CDS YP_004738054.1 340619601 10976197 4235954..4239133 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules (here, possibly oligoagarose) that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (32-104) and the Plug module (120-228) acting as a channel gate; The signal peptide is cleaved between the residues 29 and 30; Family membership; TonB-dependent Receptor 4239133 10976197 zobellia_3637 Zobellia galactanivorans TonB-dependent Receptor YP_004738054.1 4235954 D 63186 CDS YP_004738055.1 340619602 10976198 4239145..4241055 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 31 and 32; Putatively localized in the outer membrane but the determination of the membrane identity for the protein localization is not clear; Family membership; SusD/RagB family lipoprotein 4241055 10976198 zobellia_3638 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004738055.1 4239145 D 63186 CDS YP_004738056.1 340619603 10976199 4241076..4243079 1 NC_015844.1 Conserved protein containing a N-terminal domain of unknown function and a C-terminal Carbohydrate Binding Module of family 22. lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; Specificity unclear; lipoprotein 4243079 10976199 zobellia_3639 Zobellia galactanivorans lipoprotein YP_004738056.1 4241076 D 63186 CDS YP_004738057.1 340619604 10976200 4243182..4244021 1 NC_015844.1 The beta-porphyranases hydrolyse the 1,4-beta-D-galactosidic linkages in porphyrans; Belongs to the family 16 of glycoside hydrolases (GH16); Signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Hypothetical protein; beta-porphyranase E 4244021 porE 10976200 porE Zobellia galactanivorans beta-porphyranase E YP_004738057.1 4243182 D 63186 CDS YP_004738058.1 340619605 10978365 complement(4244029..4245132) 1 NC_015844.1 Aldose 1-epimerase or Mutarotase is responsible for the anomeric interconversion of aldoses between their alpha- and beta-forms; It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; Signal peptide cleaved between the residues 20 and 21; Putatively localized in the outer membrane; High confidence in function and specificity; aldose 1-epimerase 4245132 mroA3 10978365 mroA3 Zobellia galactanivorans aldose 1-epimerase YP_004738058.1 4244029 R 63186 CDS YP_004738059.1 340619606 10978185 complement(4245194..4246885) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 25; Signal peptide cleaved between the residues 29 and 30; Localized in the periplasmic space; Family membership; sulfatase 4246885 10978185 zobellia_3642 Zobellia galactanivorans sulfatase YP_004738059.1 4245194 R 63186 CDS YP_004738060.1 340619607 10976202 complement(4246919..4248310) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 19; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Family membership; sulfatase 4248310 10976202 zobellia_3643 Zobellia galactanivorans sulfatase YP_004738060.1 4246919 R 63186 CDS YP_004738061.1 340619608 10976203 complement(4248325..4249833) 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide cleaved between the residue 18 and 19; Localized in the periplasmic space; High confidence in function and specificity; alpha-L-fucosidase 4249833 fucA8 10976203 fucA8 Zobellia galactanivorans alpha-L-fucosidase YP_004738061.1 4248325 R 63186 CDS YP_004738062.1 340619609 10977865 complement(4249862..4250611) 1 NC_015844.1 Conserved protein belonging to the DUF1080 family. Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; hypothetical protein 4250611 10977865 zobellia_3645 Zobellia galactanivorans hypothetical protein YP_004738062.1 4249862 R 63186 CDS YP_004738063.1 340619610 10976204 complement(4250918..4251715) 1 NC_015844.1 Phosphomethylpyrimidine kinase also known as HMP(Hydroxymethylpyrimidine)-phosphate kinase catalyzes the phosphorylation of HMP-P to HMP-PP during the biosynthesis of thiamine; It is part of the Thiamine pyrophosphate (TPP) synthesis pathway, TPP is an essential cofactor for many enzymes; Localized in the cytoplasm; High confidence in function and specificity; phosphomethylpyrimidine kinase 4251715 thiD 10976204 thiD Zobellia galactanivorans phosphomethylpyrimidine kinase YP_004738063.1 4250918 R 63186 CDS YP_004738064.1 340619611 10978649 4252193..4263760 1 NC_015844.1 Would contain ten type-3 Thrombospondin repeats; Signal peptide cleaved between the residues 24 and 25; Putatively localized in the outer membrane; hypothetical protein 4263760 10978649 zobellia_3647 Zobellia galactanivorans hypothetical protein YP_004738064.1 4252193 D 63186 CDS YP_004738065.1 340619612 10976205 4263786..4264718 1 NC_015844.1 Conserved hypothetical protein; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; hypothetical protein 4264718 10976205 zobellia_3648 Zobellia galactanivorans hypothetical protein YP_004738065.1 4263786 D 63186 CDS YP_004738066.1 340619613 10976206 4264728..4266668 1 NC_015844.1 This protein has a modular architecture with a N-terminal TPR motif, a central beta-propeller domain, encompassing three WD40 repeats, and a C-terminal OmpA domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Signal peptide cleaved between the residues 20 and 21; localized in the periplasmic space and/or in the outer membrane; Family membership; OmpA-like periplasmic protein 4266668 10976206 zobellia_3649 Zobellia galactanivorans OmpA-like periplasmic protein YP_004738066.1 4264728 D 63186 CDS YP_004738067.1 340619614 10976207 4267518..4281656 1 NC_015844.1 Contains a N-terminal DUF 11 domain. Protein that would bind calcium ions by several EF-hand calcium-binding domains or/and by trombospondin type III domains; Signal peptide cleaved between the residues 27 and 28; Putatively localized in the outer membrane; hypothetical protein 4281656 10976207 zobellia_3650 Zobellia galactanivorans hypothetical protein YP_004738067.1 4267518 D 63186 CDS YP_004738068.1 340619615 10976209 4281683..4282615 1 NC_015844.1 Contains an uncleavable signal peptide. Localized in the cytoplasmic membrane.; Conserved hypothetical protein; membrane protein 4282615 10976209 zobellia_3651 Zobellia galactanivorans membrane protein YP_004738068.1 4281683 D 63186 CDS YP_004738069.1 340619616 10976210 4282626..4284563 1 NC_015844.1 This protein has a modular architecture with a N-terminal TPR motif, a central beta-propeller domain, encompassing three WD40 repeats, and a C-terminal OmpA domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan. The tetratrico peptide repeat (TPR) is a structural motif, which mediates proteinprotein interactions; Signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane and/or periplasmic space; Family membership; OmpA-like periplasmic protein 4284563 10976210 zobellia_3652 Zobellia galactanivorans OmpA-like periplasmic protein YP_004738069.1 4282626 D 63186 CDS YP_004738070.1 340619617 10976211 4284964..4285167 1 NC_015844.1 ThiS is involved in sulphur transfer during the thiamine biosynthesis pathway. Thiocarboxylate is formed at the last G in the activation process. Sulphur is transferred from ThiI to ThiS in a reaction catalysed by IscS; Contains two conserved glycines at the C-terminus; Localized in the cytoplasm; High confidence in function and specificity; sulfur transfer protein ThiS 4285167 thiS 10976211 thiS Zobellia galactanivorans sulfur transfer protein ThiS YP_004738070.1 4284964 D 63186 CDS YP_004738071.1 340619618 10978654 4285275..4287134 1 NC_015844.1 ThiC is involved in thiamine biosynthesis, but its precise catalytic function is still unknown. It is required for the synthesis of the hydromethylpyrimidine moiety of thiamine (4-amino-2-methyl-5- hydroxymethylpyrimidine). Localized in the cytoplasm.; High confidence in function and specificity; thiamine biosynthesis protein thiC 4287134 thiC 10978654 thiC Zobellia galactanivorans thiamine biosynthesis protein thiC YP_004738071.1 4285275 D 63186 CDS YP_004738072.1 340619619 10978648 4287145..4287777 1 NC_015844.1 Conserved protein distantly related to Thiamine-phosphate synthase (ThiE); Localized in the cytoplasm; Function unclear; thiamine-phosphate synthase-like protein 4287777 10978648 zobellia_3655 Zobellia galactanivorans thiamine-phosphate synthase-like protein YP_004738072.1 4287145 D 63186 CDS YP_004738073.1 340619620 10976212 4287783..4288436 1 NC_015844.1 Thiamine-phosphate pyrophosphorylase (or Thiamine monophosphate synthase) is involved in thiamine biosynthesis. It catalyzes the substitution of the pyrophosphate of 2-methyl-4-amino-5-hydroxymethylpyrimidine pyrophosphate by 4-methyl-5- (beta-hydroxyethyl)thiazole phosphate to yield thiamine phosphate. It binds one magnesium ion as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; thiamine-phosphate pyrophosphorylase 4288436 thiE 10976212 thiE Zobellia galactanivorans thiamine-phosphate pyrophosphorylase YP_004738073.1 4287783 D 63186 CDS YP_004738074.1 340619621 10978650 4288439..4289209 1 NC_015844.1 The protein ThiG is required for the synthesis of the thiazole moiety of thiamine (vitamin B1); Binds FMN as cofactor; Localized in the cytoplasm; High confidence in function and specificity; thiazole biosynthesis protein thiG 4289209 thiG 10978650 thiG Zobellia galactanivorans thiazole biosynthesis protein thiG YP_004738074.1 4288439 D 63186 CDS YP_004738075.1 340619622 10978651 4289220..4290326 1 NC_015844.1 The protein ThiH is required for the synthesis of the thiazole moiety of thiamine (vitamin B1); Binds one 4Fe-4S cluster, which is coordinated with three cysteines and an exchangeable S-adenosyl-L-methionine; Localized in the cytoplasm; High confidence in function and specificity; thiamine biosynthesis protein thiH 4290326 thiH 10978651 thiH Zobellia galactanivorans thiamine biosynthesis protein thiH YP_004738075.1 4289220 D 63186 CDS YP_004738076.1 340619623 10978652 complement(4290347..4291159) 1 NC_015844.1 Enzyme responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA by rotation of the C1'-N-1 glycosidic bond of uridine to a C1'-C5; Contains a N-terminal S4 RNA- binding domain that probably mediates binding to RNA; Belongs to the pseudouridine synthase RluA family; localized in the cytoplasm; High confidence in function and specificity; ribosomal large subunit pseudouridine synthase C 4291159 rluC 10978652 rluC Zobellia galactanivorans ribosomal large subunit pseudouridine synthase C YP_004738076.1 4290347 R 63186 CDS YP_004738077.1 340619624 10978470 complement(4291299..4292063) 1 NC_015844.1 Conserved protein belonging to the DUF1275 family; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4292063 10978470 zobellia_3660 Zobellia galactanivorans membrane protein YP_004738077.1 4291299 R 63186 CDS YP_004738078.1 340619625 10976214 4292215..4292307 1 NC_015844.1 Hypothetical protein; hypothetical protein 4292307 10976214 zobellia_3661 Zobellia galactanivorans hypothetical protein YP_004738078.1 4292215 D 63186 CDS YP_004738079.1 340619626 10976215 complement(4292539..4292958) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 4292958 10976215 zobellia_3662 Zobellia galactanivorans hypothetical protein YP_004738079.1 4292539 R 63186 CDS YP_004738080.1 340619627 10976216 complement(4292992..4293519) 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 4293519 10976216 zobellia_3663 Zobellia galactanivorans membrane protein YP_004738080.1 4292992 R 63186 CDS YP_004738081.1 340619628 10976217 4293739..4294968 1 NC_015844.1 Conserved protein containing a N-terminal domain of unknown function and six C-terminal tetratrico peptide repeats. TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Function unclear; hypothetical protein 4294968 10976217 zobellia_3664 Zobellia galactanivorans hypothetical protein YP_004738081.1 4293739 D 63186 CDS YP_004738082.1 340619629 10976218 4295074..4295700 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Localized in the cytoplasm; Specificity unclear; two-component system-sensor histidine kinase 4295700 10976218 zobellia_3665 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738082.1 4295074 D 63186 CDS YP_004738083.1 340619630 10976219 4295703..4296437 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, which acts as transcriptional regulator. Localized in the cytoplasm.; Specificity unclear; two-component system-response regulator 4296437 10976219 zobellia_3666 Zobellia galactanivorans two-component system-response regulator YP_004738083.1 4295703 D 63186 CDS YP_004738084.1 340619631 10976220 complement(4296655..4298787) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4298787 10976220 zobellia_3667 Zobellia galactanivorans hypothetical protein YP_004738084.1 4296655 R 63186 CDS YP_004738085.1 340619632 10976221 complement(4298978..4299718) 1 NC_015844.1 Shikimate dehydrogenase catalyzes the fourth step of The shikimate pathway. In a NADP+-dependent reaction, AroE converts the shikimate to 3-dehydroshikimate. The N-terminal domain is the shikimate-binding domain and consists of a mainly parallel six-stranded beta-sheet and six alpha-helices. The C-terminal NADP-binding domain adopts a nearly canonical Rossmann fold; Localized in the cytoplasm; High confidence in function and specificity; shikimate dehydrogenase 4299718 aroE 10976221 aroE Zobellia galactanivorans shikimate dehydrogenase YP_004738085.1 4298978 R 63186 CDS YP_004738086.1 340619633 10977547 complement(4299750..4300778) 1 NC_015844.1 Conserved protein belonging to the DUF368 family; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4300778 10977547 zobellia_3669 Zobellia galactanivorans membrane protein YP_004738086.1 4299750 R 63186 CDS YP_004738087.1 340619634 10976222 complement(4300789..4301703) 1 NC_015844.1 Conserved protein belonging to the DUF368 family; Contains six transmembrane helices; Localized in the cytoplasmic membrane.; Conserved hypothetical protein; membrane protein 4301703 10976222 zobellia_3670 Zobellia galactanivorans membrane protein YP_004738087.1 4300789 R 63186 CDS YP_004738088.1 340619635 10976223 complement(4301819..4303219) 1 NC_015844.1 Conserved protein containing ten tetratrico peptide repeats (TPRs). TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Localized in the cytoplasm; Function unclear; hypothetical protein 4303219 10976223 zobellia_3671 Zobellia galactanivorans hypothetical protein YP_004738088.1 4301819 R 63186 CDS YP_004738089.1 340619636 10976224 complement(4303317..4304498) 1 NC_015844.1 Acetylornithine aminotransferase is involved in the Urea cycle and metabolism of amino groups. It catalyzes the transfer of an amino group from acetylornithine to alpha-ketoglutarate, yielding N-acetyl-glutamic-5-semi-aldehyde and glutamic acid; Uses the Pyridoxal phosphate as cofactor linked to a conserved lysine residue; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity; acetylornithine aminotransferase 4304498 10976224 zobellia_3672 Zobellia galactanivorans acetylornithine aminotransferase YP_004738089.1 4303317 R 63186 CDS YP_004738090.1 340619637 10976225 complement(4304495..4306237) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4306237 10976225 zobellia_3673 Zobellia galactanivorans periplasmic protein YP_004738090.1 4304495 R 63186 CDS YP_004738091.1 340619638 10976226 complement(4306403..4307674) 1 NC_015844.1 Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. It forms a homodimer and binds one magnesium ion per subunit. Localized in the cytoplasm.; High confidence in function and specificity; adenylosuccinate synthase 4307674 purA 10976226 purA Zobellia galactanivorans adenylosuccinate synthase YP_004738091.1 4306403 R 63186 CDS YP_004738092.1 340619639 10978403 complement(4307687..4308142) 1 NC_015844.1 Ferric uptake regulation protein is a transcriptional regulator that acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed metal ion-responsive genes. It regulates the expression of several outer- membrane proteins including the iron transport operon; Contains a N-terminal Fur-type HTH DNA-binding domain; Belongs to the Fur family; Localized in the cytoplasm; High confidence in function and specificity; ferric uptake regulation protein 4308142 furA1 10978403 furA1 Zobellia galactanivorans ferric uptake regulation protein YP_004738092.1 4307687 R 63186 CDS YP_004738093.1 340619640 10977870 complement(4308197..4310401) 1 NC_015844.1 GTP pyrophosphokinase catalyzes the formation of pppGpp which is then hydrolyzed to form ppGpp. The ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance; Contains a HD domain involved in the coordination of divalent cations, a TGS domain that could play a nucleotide-binding and regulatory role and a C-terminal ACT domain; Belongs to the relA/spoT family; Localized in the cytoplasm;, Contains .,; High confidence in function and specificity; GTP pyrophosphokinase 4310401 relA 10977870 relA Zobellia galactanivorans GTP pyrophosphokinase YP_004738093.1 4308197 R 63186 CDS YP_004738094.1 340619641 10978450 complement(4310506..4311732) 1 NC_015844.1 CAAX prenyl protease 1 proteolytically removes the C-terminal three residues of farnesylated proteins, Subsequently, the S-isoprenylated cysteine residue that forms the new C-terminus is methyl-esterified and forms a hydrophobic membrane-anchor; Binds 1 zinc ion per subunit; Contains seven transmembrane segments; Belongs to the peptidase M48A family (Ste24 endopeptidase family); Localized in the cytoplasmic membrane; High confidence in function and specificity; CAAX prenyl protease 1 4311732 10978450 zobellia_3677 Zobellia galactanivorans CAAX prenyl protease 1 YP_004738094.1 4310506 R 63186 CDS YP_004738095.1 340619642 10976227 complement(4311787..4312599) 1 NC_015844.1 Catalyzes the site-specific methylation of the 2' hydroxy group of the ribose in rRNA or tRNA, using the S-AdoMet; Contains a N-terminal RNA 2'-O ribose methyltransferase substrate binding domain and a C-terminal catalytic domain also involved in the dimer formation that adopts an alpha/beta knot fold; Belongs to the RNA methyltransferase TrmH family; Localized in the cytoplasm; Family membership; tRNA/rRNA methyltransferase 4312599 10976227 zobellia_3678 Zobellia galactanivorans tRNA/rRNA methyltransferase YP_004738095.1 4311787 R 63186 CDS YP_004738096.1 340619643 10976228 4312661..4313461 1 NC_015844.1 Contains a lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4313461 10976228 zobellia_3679 Zobellia galactanivorans lipoprotein YP_004738096.1 4312661 D 63186 CDS YP_004738097.1 340619644 10976229 4313763..4314173 1 NC_015844.1 Molybdopterin synthase converts molybdopterin precursor Z into molybdopterin in the second major step of the molybdenum cofactor biosynthesis. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group responsible for molybdenum ligation; The enzyme is a heterodimer of 2 small (moaD) subunits and 2 large (moaE) subunits; Localized in the cytoplasm; High confidence in function and specificity; molybdopterin synthase, large subunit 4314173 moaE1 10976229 moaE1 Zobellia galactanivorans molybdopterin synthase, large subunit YP_004738097.1 4313763 D 63186 CDS YP_004738098.1 340619645 10978165 4314252..4315235 1 NC_015844.1 Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z; Binds 2 4Fe-4S clusters: 1 4Fe-4S cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 4Fe-4S cluster coordinated with 3 cysteines and the GTP-derived substrate; Contains an N-terminal SAM domain; Belongs to the radical SAM superfamily; Localized in the cytoplasm; High confidence in function and specificity; molybdenum cofactor biosynthesis protein A 4315235 moaA 10978165 moaA Zobellia galactanivorans molybdenum cofactor biosynthesis protein A YP_004738098.1 4314252 D 63186 CDS YP_004738099.1 340619646 10978163 4315240..4315713 1 NC_015844.1 Involved in molybdenum cofactor biosynthesis, MoaC, a small hexameric protein, converts, together with MoaA, a guanosine derivative to the precursor Z by inserting the carbon-8 of the purine between the 2' and 3' ribose carbon atoms, which is the first of three phases of molybdenum cofactor biosynthesis; Localized in the cytoplasm; High confidence in function and specificity; molybdenum cofactor biosynthesis protein C 4315713 moaC 10978163 moaC Zobellia galactanivorans molybdenum cofactor biosynthesis protein C YP_004738099.1 4315240 D 63186 CDS YP_004738100.1 340619647 10978164 4315697..4316293 1 NC_015844.1 Links a guanosine 5'-phosphate to molydopterin forming molybdopterin guanine dinucleotide (MGD); Localized in the cytoplasm; High confidence in function and specificity; molybdopterin-guanine dinucleotide biosynthesis protein A 4316293 mobA 10978164 mobA Zobellia galactanivorans molybdopterin-guanine dinucleotide biosynthesis protein A YP_004738100.1 4315697 D 63186 CDS YP_004738101.1 340619648 10978167 4316290..4317363 1 NC_015844.1 Enzyme involved in the biosynthesis of molybdopterin cofactor, necessary for molybdoenzymes. Plays a role in the activation of the small subunit of the molybdopterin converting factor (moaD); Contains a N- terminal transmembrane segment and a C-terminal rhodanese domain; Belongs to the hesA/moeB/thiF family; Localized in the cytoplasmic membrane; High confidence in function and specificity; molybdopterin synthase activating protein 4317363 moeB 10978167 moeB Zobellia galactanivorans molybdopterin synthase activating protein YP_004738101.1 4316290 D 63186 CDS YP_004738102.1 340619649 10978173 4317347..4318123 1 NC_015844.1 Permease without known function; Contains seven transmembranne segments; Belongs to the DUF81 family; Localized in the cytoplasmic membrane; Specificity unclear; permease 4318123 10978173 zobellia_3685 Zobellia galactanivorans permease YP_004738102.1 4317347 D 63186 CDS YP_004738103.1 340619650 10976230 4318151..4318783 1 NC_015844.1 Protein that consists of a WbqC-like domain functionally uncharacterised; Could belong to the WbqC-like protein family; Localized in the cytoplasm; hypothetical protein 4318783 10976230 zobellia_3686 Zobellia galactanivorans hypothetical protein YP_004738103.1 4318151 D 63186 CDS YP_004738104.1 340619651 10976231 4318776..4319096 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4319096 10976231 zobellia_3687 Zobellia galactanivorans membrane protein YP_004738104.1 4318776 D 63186 CDS YP_004738105.1 340619652 10976232 complement(4319076..4320101) 1 NC_015844.1 The Endonuclease/exonuclease/phosphatase domain is found in a large number of proteins including magnesium dependent endonucleases and phosphatases involved in intracellular signalling; Contains two N-terminal transmembrane segments; Belongs to the Endonuclease/Exonuclease/ phosphatase family; Possible signal peptide of lipoprotein cleaved between the residues 25 and 26; Localized in the cytoplasmic membrane; Family membership; endonuclease/exonuclease/phosphatase family protein 4320101 10976232 zobellia_3688 Zobellia galactanivorans endonuclease/exonuclease/phosphatase family protein YP_004738105.1 4319076 R 63186 CDS YP_004738106.1 340619653 10976233 complement(4320105..4320974) 1 NC_015844.1 Serine endopeptidase belonging to the family S54. This family includes the protein Rhomboid which is a peptidase important for embryo development in Drosophila melanogaster. The active site is a catalytic diad Ser, His. Features seven transmembrane helices. Localized in the cytoplasmic membrane.; Specificity unclear; serine endopeptidase 4320974 10976233 zobellia_3689 Zobellia galactanivorans serine endopeptidase YP_004738106.1 4320105 R 63186 CDS YP_004738107.1 340619654 10976234 complement(4320976..4321719) 1 NC_015844.1 Serine endopeptidase belonging to the family S54. This family includes the protein Rhomboid which is a peptidase important for embryo development in Drosophila melanogaster. The active site is a catalytic diad Ser, His. Features six transmembrane helices. Localized in the cytoplasmic membrane.; Specificity unclear; serine endopeptidase 4321719 10976234 zobellia_3690 Zobellia galactanivorans serine endopeptidase YP_004738107.1 4320976 R 63186 CDS YP_004738108.1 340619655 10976235 complement(4321720..4323576) 1 NC_015844.1 MutL is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a \\molecular matchmaker\\, a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. Localized in the cytoplasm.; High confidence in function and specificity; DNA mismatch repair protein MutL 4323576 mutL 10976235 mutL Zobellia galactanivorans DNA mismatch repair protein MutL YP_004738108.1 4321720 R 63186 CDS YP_004738109.1 340619656 10978211 complement(4323576..4323875) 1 NC_015844.1 Contains a C-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4323875 10978211 zobellia_3692 Zobellia galactanivorans membrane protein YP_004738109.1 4323576 R 63186 CDS YP_004738110.1 340619657 10976236 complement(4324108..4324590) 1 NC_015844.1 Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2-butanone-4-phosphate via 6,7-dimethyl-8-lumazine. It consists of 3 alpha subunits and 60 beta subunits. The beta subunits are arranged in twelve pentamers that give rise to a capsid. The capsid encloses the trimer of alpha subunits. The beta subunit catalyzes the condensation of 5-amino-6-(1'-D)-ribityl-amino- 2,4(1H, 3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate yielding 6,7-dimethyl-8-lumazine. Localized in the cytoplasm.; High confidence in function and specificity; riboflavin synthase subunit beta 4324590 ribH 10976236 ribH Zobellia galactanivorans riboflavin synthase subunit beta YP_004738110.1 4324108 R 63186 CDS YP_004738111.1 340619658 10978464 complement(4324590..4325357) 1 NC_015844.1 Conserved protein containing three C-terminal tetratrico peptide repeats (TPRs). TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes; Contains a transmembrane helix in the N-terminal region; Localized in the cytoplasmic membrane; Function unclear; hypothetical protein 4325357 10978464 zobellia_3694 Zobellia galactanivorans hypothetical protein YP_004738111.1 4324590 R 63186 CDS YP_004738112.1 340619659 10976237 4325472..4326557 1 NC_015844.1 The recF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. Localized in the cytoplasm.; High confidence in function and specificity; DNA replication and repair protein RecF 4326557 recF 10976237 recF Zobellia galactanivorans DNA replication and repair protein RecF YP_004738112.1 4325472 D 63186 CDS YP_004738113.1 340619660 10978442 4326600..4327016 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4327016 10978442 zobellia_3696 Zobellia galactanivorans periplasmic protein YP_004738113.1 4326600 D 63186 CDS YP_004738114.1 340619661 10976238 4327020..4327316 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 4327316 10976238 zobellia_3697 Zobellia galactanivorans hypothetical protein YP_004738114.1 4327020 D 63186 CDS YP_004738115.1 340619662 10976239 complement(4327381..4327800) 1 NC_015844.1 Nucleoside diphosphate kinase (NDK) is an important housekeeping enzyme involved in the production of the NTPs and dNTPs (other than ATP) vital for DNA and RNA synthesis and macromolecular metabolism; NDKs are proteins that act via a ping-pong mechanism in which a histidine residue is phosphorylated, by transfer of the gamma phosphate group from ATP. In the presence of magnesium, the phosphoenzyme can transfer its phosphate group to any beta phosphate group of the NDP, to produce an NTP; Localized in the cytoplasm; High confidence in function and specificity; nucleoside diphosphate kinase 4327800 ndkA 10976239 ndkA Zobellia galactanivorans nucleoside diphosphate kinase YP_004738115.1 4327381 R 63186 CDS YP_004738116.1 340619663 10978244 complement(4327849..4328898) 1 NC_015844.1 Alkaline phosphatase is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH; Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymic activity; Signal peptide of lipoprotein cleaved between the residues 16 and 17; Localized in the outer membrane; High confidence in function and specificity; alkaline phosphatase 4328898 phoD3 10978244 phoD3 Zobellia galactanivorans alkaline phosphatase YP_004738116.1 4327849 R 63186 CDS YP_004738117.1 340619664 10978349 4328977..4329993 1 NC_015844.1 Contains a N-terminal DHH domain predicted as phosphoesterase and a C-terminal DHHA1 domain; It is predicted that this family of proteins all perform a phosphoesterase function; Belongs to the DHH family; Localized in the cytoplasm; Specificity unclear; phosphoesterase 4329993 10978349 zobellia_3700 Zobellia galactanivorans phosphoesterase YP_004738117.1 4328977 D 63186 CDS YP_004738118.1 340619665 10976241 4329990..4330541 1 NC_015844.1 GldI, lipoprotein required for gliding motility, contains a Peptidyl-prolyl cis-trans isomerase (PPIase) domain; PPIases catalyze the peptidyl-prolyl isomerisation of the peptide bond preceding proline that is stabilised in the cis conformation in oligopeptides; GldI may be involved in folding cell envelope protein components of the motility machinery; Signal peptide cleaved between the residues 14 and 15; Localized in the outer membrane or/and cytoplasmic membrane; High confidence in function and specificity; gliding motility FKBP-type peptidyl-prolyl cis-trans isomerase 4330541 gldI 10976241 gldI Zobellia galactanivorans gliding motility FKBP-type peptidyl-prolyl cis-trans isomerase YP_004738118.1 4329990 D 63186 CDS YP_004738119.1 340619666 10977906 4330592..4331704 1 NC_015844.1 Peptidyl-prolyl cis-trans isomerase, or PPIase or rotamase, accelerates the folding of proteins. It catalyzes the peptidyl-prolyl isomerisation during which the peptide bond preceding proline is stabilised in the cis conformation in oligopeptides; Contains a N-terminal Cyclophilin type PPIase/CLD domain and a C-terminal FKBP-type peptidyl-prolyl cis-trans isomerase domain; Signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; High confidence in function and specificity; peptidyl-prolyl cis-trans isomerase 4331704 ppiA 10977906 ppiA Zobellia galactanivorans peptidyl-prolyl cis-trans isomerase YP_004738119.1 4330592 D 63186 CDS YP_004738120.1 340619667 10978371 4331877..4332953 1 NC_015844.1 BglC hydrolyzes the beta-1,4 linkages of carboxylmethylcellulose; Belongs to the family 5 of the glycoside hydrolases (GH5); Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the cytoplasmic membrane; High confidence in function and specificity; endo-beta-1,4-glucanase 4332953 bglC 10978371 bglC Zobellia galactanivorans endo-beta-1,4-glucanase YP_004738120.1 4331877 D 63186 CDS YP_004738121.1 340619668 10977600 4333220..4333576 1 NC_015844.1 Conserved protein belonging to the DUF805 family. Features two transmembrane helices. Localized in the cytoplasmic membrane.; Conserved hypothetical protein; hypothetical protein 4333576 10977600 zobellia_3704 Zobellia galactanivorans hypothetical protein YP_004738121.1 4333220 D 63186 CDS YP_004738122.1 340619669 10976242 complement(4333633..4335093) 1 NC_015844.1 Xaa-His dipeptidase, also known as aminoacyl-histidine dipeptidase, catalyzes the hydrolysis of Xaa-|-His dipeptides. This dipeptidase has specificity for the unusual dipeptide beta-alanyl-L-histidine. Belongs to the family M20 of the metallopeptidase. PepD binds two co-catalytic zinc ions, which are coordinated by five conserved residues (His/Asp, Asp, Glu, Glu/Asp, His). The zinc ions stabilize the tetrahedral intermediate and activate the catalytic water molecule. Localized in the cytoplasm.; High confidence in function and specificity; Xaa-His dipeptidase, family M20 4335093 pepD2 10976242 pepD2 Zobellia galactanivorans Xaa-His dipeptidase, family M20 YP_004738122.1 4333633 R 63186 CDS YP_004738123.1 340619670 10978326 4335249..4336316 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4336316 10978326 zobellia_3706 Zobellia galactanivorans membrane protein YP_004738123.1 4335249 D 63186 CDS YP_004738124.1 340619671 10976243 complement(4336366..4337556) 1 NC_015844.1 Enzyme Involved in the biosynthesis of molybdopterin, necessary for molybdo-enzymes. MoeA, together with MoaB, is responsible for the metal incorporation into molybdopterin, the third step in molybdenum cofactor biosynthesis; Binds one magnesium ion; Localized in the cytoplasm; High confidence in function and specificity; molybdopterin biosynthesis protein 4337556 moeA2 10976243 moeA2 Zobellia galactanivorans molybdopterin biosynthesis protein YP_004738124.1 4336366 R 63186 CDS YP_004738125.1 340619672 10978172 complement(4337590..4339290) 1 NC_015844.1 The type-1 signal peptidase (SPase I; also known as leader peptidase I) is a serine protease that removes the signal peptides from the majority of exported pre-proteins. SPase I is an integral membrane protein that is anchored in the cytoplasmic membrane by four N-terminal transmembrane segments with the main part of the protein protuding in the periplasmic space; Contains an additional C-terminal transmembrane segments; Belongs to family 26 (clan SF) of serine peptidases (S26), S26A subfamily; High confidence in function and specificity; signal peptidase I, family s26 4339290 lepB 10978172 lepB Zobellia galactanivorans signal peptidase I, family s26 YP_004738125.1 4337590 R 63186 CDS YP_004738126.1 340619673 10978079 complement(4339396..4340097) 1 NC_015844.1 Dihydrodipicolinate reductase reduces the alpha, beta-unsaturated cyclic imine, dihydro-dipicolinate. This reaction is the second committed step in the biosynthesis of L-lysine and its precursor meso- diaminopimelate, which are critical for both protein and cell wall biosynthesis. DapB activity is repressed by lysine. It forms a homotetramer and binds one NAD(P) per subunit as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; dihydrodipicolinate reductase 4340097 dapB 10978079 dapB Zobellia galactanivorans dihydrodipicolinate reductase YP_004738126.1 4339396 R 63186 CDS YP_004738127.1 340619674 10977716 complement(4340148..4340789) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4340789 10977716 zobellia_3710 Zobellia galactanivorans periplasmic protein YP_004738127.1 4340148 R 63186 CDS YP_004738128.1 340619675 10976244 complement(4340782..4341684) 1 NC_015844.1 ParB is involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. Localized in the cytoplasm.; High confidence in function and specificity; chromosome-partitioning protein parB 4341684 parB 10976244 parB Zobellia galactanivorans chromosome-partitioning protein parB YP_004738128.1 4340782 R 63186 CDS YP_004738129.1 340619676 10978302 complement(4341684..4342457) 1 NC_015844.1 ParA is cnvolved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Localized in the cytoplasm.; High confidence in function and specificity; chromosome partitioning protein ParA 4342457 parA 10978302 parA Zobellia galactanivorans chromosome partitioning protein ParA YP_004738129.1 4341684 R 63186 CDS YP_004738130.1 340619677 10978301 complement(4342871..4343203) 1 NC_015844.1 DivIC is required for septum formation. Required for the activation of genes expressed under the control of the sporulation transcription factors sigma F and sigma E. Localized in the cytoplasm.; High confidence in function and specificity; cell division protein DivIC 4343203 divIC 10978301 divIC Zobellia galactanivorans cell division protein DivIC YP_004738130.1 4342871 R 63186 CDS YP_004738131.1 340619678 10977746 complement(4343206..4343814) 1 NC_015844.1 Uridine kinase (pyrimidine ribonucleoside kinase) is the rate-limiting enzyme in the pyrimidine salvage pathway. It catalyzes the reactions: ATP + uridine = ADP + UMP and ATP + cytidine = ADP + CMP. It forms a homotetramer and binds a ATP per subunit as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; uridine kinase 4343814 udk 10977746 udk Zobellia galactanivorans uridine kinase YP_004738131.1 4343206 R 63186 CDS YP_004738132.1 340619679 10978721 4343924..4345132 1 NC_015844.1 The Drug resistance transporter, Bcr/CflA family belongs to the major facilitator superfamily (MFS) transporters. They are single-polypeptide secondary carriers capable only of transporting small solutes (probably antibiotics in this case) in response to chemiosmotic ion gradients; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; Drug resistance transporter 4345132 10978721 zobellia_3715 Zobellia galactanivorans Drug resistance transporter YP_004738132.1 4343924 D 63186 CDS YP_004738133.1 340619680 10976245 complement(4345222..4347129) 1 NC_015844.1 Acetyl-coenzyme A synthetase, also known as Acetate-CoA ligase, enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt. It catalyzes the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. Belongs to the ATP-dependent AMP-binding enzyme family. Localized in the cytoplasm.; High confidence in function and specificity; acetyl-coenzyme A synthetase 4347129 acs 10976245 acs Zobellia galactanivorans acetyl-coenzyme A synthetase YP_004738133.1 4345222 R 63186 CDS YP_004738134.1 340619681 10977470 complement(4347226..4348938) 1 NC_015844.1 Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains thirteen transmembrane helices; Localized in the cytoplasmic membrane; Family membership; sodium/solute symporter 4348938 10977470 zobellia_3717 Zobellia galactanivorans sodium/solute symporter YP_004738134.1 4347226 R 63186 CDS YP_004738135.1 340619682 10976246 complement(4348960..4349220) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4349220 10976246 zobellia_3718 Zobellia galactanivorans membrane protein YP_004738135.1 4348960 R 63186 CDS YP_004738136.1 340619683 10976247 complement(4349278..4350357) 1 NC_015844.1 Conserved protein belonging to the UPF0075 family. Localized in the cytoplasm.; Family membership; hypothetical protein 4350357 10976247 zobellia_3719 Zobellia galactanivorans hypothetical protein YP_004738136.1 4349278 R 63186 CDS YP_004738137.1 340619684 10976248 complement(4350354..4351934) 1 NC_015844.1 Beta-N-acetylglucosaminidase catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides. It belongs to the family 3 of the glycoside hydrolases.; High confidence in function and specificity; beta-N-acetylglucosaminidase 4351934 10976248 zobellia_3720 Zobellia galactanivorans beta-N-acetylglucosaminidase YP_004738137.1 4350354 R 63186 CDS YP_004738138.1 340619685 10976249 complement(4351927..4353201) 1 NC_015844.1 Protein AmpG is a signal transducer in beta-lactamase induction. It probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling. Belongs to the major facilitator superfamily. Features twelve transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; protein AmpG 4353201 ampG 10976249 ampG Zobellia galactanivorans protein AmpG YP_004738138.1 4351927 R 63186 CDS YP_004738139.1 340619686 10977519 complement(4353473..4355404) 1 NC_015844.1 Bifunctional enzyme with a N-terminal glucosamine-6-phosphate (GlcN6P) deaminase domain and a C-terminal deacetylase domain. GlcN6P deaminase catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate to form fructose 6-phosphate and ammonium ion in the N-acetylglucosamine utilization pathway. Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. The C-terminal domain belongs to the PIG-L family, which includes various deacetylases, such as the mammalian and yeast N-acetylglucosaminylphosphatidylinositol de-N-acetylase and the diacetylchitobiose deacetylase from Pyrococcus kodakaraensis. The specificity of this C-terminal deacetylase is unclear. Localized in the cytoplasm.; Specificity unclear; glucosamine-6-phosphate deaminase / PIg-L family deacetylase 4355404 nagB2 10977519 nagB2 Zobellia galactanivorans glucosamine-6-phosphate deaminase / PIg-L family deacetylase YP_004738139.1 4353473 R 63186 CDS YP_004738140.1 340619687 10978227 4355596..4356345 1 NC_015844.1 DeoR-type transcription regulator are repressors of sugar and nucleoside metabolic systems. The effector molecules are generally phosphorylated intermediates of the relevant metabolic pathway. Contains a N-terminal DNA-binding DeoR-type HTH domain. The C-terminal part can contain an effector-binding domain and/or an oligomerization domain. Localized in the cytoplasm.; Specificity unclear; DeoR-type transcriptional regulator 4356345 10978227 zobellia_3723 Zobellia galactanivorans DeoR-type transcriptional regulator YP_004738140.1 4355596 D 63186 CDS YP_004738141.1 340619688 10976250 4356351..4357160 1 NC_015844.1 MurQ specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Is required for growth on MurNAc as the sole source of carbon and energy. Together with anmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. Localized in the cytoplasm.; High confidence in function and specificity; N-acetylmuramic acid 6-phosphate etherase 4357160 murQ 10976250 murQ Zobellia galactanivorans N-acetylmuramic acid 6-phosphate etherase YP_004738141.1 4356351 D 63186 CDS YP_004738142.1 340619689 10978208 complement(4357162..4357575) 1 NC_015844.1 Cytochromes c typically function in electron transfer. The heme group is covalently attached by thioether bonds to two conserved cysteine residues (Cys-x-x-Cys-His motif). The conserved histidine residue is one of the two axial ligands of the heme iron. Features a signal peptide cleaved between the residues 24 and 25. Localized in the periplasm.; Specificity unclear; cytochrome c 4357575 10978208 zobellia_3725 Zobellia galactanivorans cytochrome c YP_004738142.1 4357162 R 63186 CDS YP_004738143.1 340619690 10976251 complement(4357599..4358720) 1 NC_015844.1 Lipoprotein putatively localized in the outer membrane is a soluble glucose dehydrogenase (s-GDH) that oxidizes glucose to gluconolactone using a quinone as cofactor; Signale peptide cleaved between the residues 18 and 19; Family membership; quinoprotein glucose dehydrogenase 4358720 gdhB3 10976251 gdhB3 Zobellia galactanivorans quinoprotein glucose dehydrogenase YP_004738143.1 4357599 R 63186 CDS YP_004738144.1 340619691 10977890 4358859..4367642 1 NC_015844.1 Signal peptide cleaved between the residues 27 and 28; Putatively localized in the outer membrane (PSORT result); hypothetical protein 4367642 10977890 zobellia_3727 Zobellia galactanivorans hypothetical protein YP_004738144.1 4358859 D 63186 CDS YP_004738145.1 340619692 10976252 4367769..4368488 1 NC_015844.1 Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted carbohydrates; Belongs to the family 1 of the carbohydrate esterases (CE1); Prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Specificity unclear; carbohydrate esterase 4368488 10976252 zobellia_3728 Zobellia galactanivorans carbohydrate esterase YP_004738145.1 4367769 D 63186 CDS YP_004738146.1 340619693 10976253 complement(4368673..4369785) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4369785 10976253 zobellia_3729 Zobellia galactanivorans hypothetical protein YP_004738146.1 4368673 R 63186 CDS YP_004738147.1 340619694 10976254 complement(4369859..4370959) 1 NC_015844.1 Conserved protein belonging to the DUF20 family proteins predicted to be permeases; Contains eight transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4370959 10976254 zobellia_3730 Zobellia galactanivorans membrane protein YP_004738147.1 4369859 R 63186 CDS YP_004738148.1 340619695 10976256 complement(4370988..4371638) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4371638 10976256 zobellia_3731 Zobellia galactanivorans periplasmic protein YP_004738148.1 4370988 R 63186 CDS YP_004738149.1 340619696 10976257 complement(4371862..4372569) 1 NC_015844.1 RsmE, previously known as YggJ, is a SAM-dependent methyltransferase which specifically methylates U1498 in 16S ribosomal RNA. Belongs to the alpha/beta knot methyltransferase family. Localized in the cytoplasm.; High confidence in function and specificity; m3U1498 16S rRNA methyltransferase 4372569 rsmE 10976257 rsmE Zobellia galactanivorans m3U1498 16S rRNA methyltransferase YP_004738149.1 4371862 R 63186 CDS YP_004738150.1 340619697 10978556 complement(4372645..4373682) 1 NC_015844.1 The cohemolysin CamP is a O-sialoglycoprotein endopeptidase. In glycophorin A, this enzyme cleaves the Arg31-Asp32 bond. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated. Belongs to the family 22 of the metallopeptidases. The catalytic motif encompasses two conserved histidines which bind a zinc ion. Secreted in the extracellular medium.; High confidence in function and specificity; o-Sialoglycoprotein endopeptidase 4373682 camP 10978556 camP Zobellia galactanivorans o-Sialoglycoprotein endopeptidase YP_004738150.1 4372645 R 63186 CDS YP_004738151.1 340619698 10977614 4373764..4378194 1 NC_015844.1 Contains a signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4378194 10977614 zobellia_3734 Zobellia galactanivorans periplasmic protein YP_004738151.1 4373764 D 63186 CDS YP_004738152.1 340619699 10976258 4378467..4379453 1 NC_015844.1 6-Phosphofructokinase catalyzes the thirth step of glycolysis (Embden-Meyerhof pathway). It phosphoryles the D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. It is an allosteric homotetramer enzyme. Because the reaction catalyzed by Phosphofructokinase is energetically very favorable, it is essentially irreversible; Belongs to the carbohydrate kinase family; Localized in the cytoplasm; High confidence in function and specificity; 6-phosphofructokinase, isoenzyme 1 4379453 pfkA 10976258 pfkA Zobellia galactanivorans 6-phosphofructokinase, isoenzyme 1 YP_004738152.1 4378467 D 63186 CDS YP_004738153.1 340619700 10978330 4379476..4380477 1 NC_015844.1 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity; glyceraldehyde 3-phosphate dehydrogenase 4380477 gapA 10978330 gapA Zobellia galactanivorans glyceraldehyde 3-phosphate dehydrogenase YP_004738153.1 4379476 D 63186 CDS YP_004738154.1 340619701 10977877 4380560..4381411 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4381411 10977877 zobellia_3737 Zobellia galactanivorans hypothetical protein YP_004738154.1 4380560 D 63186 CDS YP_004738155.1 340619702 10976259 complement(4381472..4381852) 1 NC_015844.1 Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Belongs to the ribonuclease L-PSP family. This family includes the rat liver perchloric acid-soluble protein (L-PSP), which has been shown to be a ribonuclease, and the protein yabJ from Bacillus subtilis involved in the regulation of the purine biosynthetic gene purA. Localized in the cytoplasm.; Family membership; endoribonuclease 4381852 10976259 zobellia_3738 Zobellia galactanivorans endoribonuclease YP_004738155.1 4381472 R 63186 CDS YP_004738156.1 340619703 10976260 complement(4381920..4384661) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4384661 10976260 zobellia_3739 Zobellia galactanivorans periplasmic protein YP_004738156.1 4381920 R 63186 CDS YP_004738157.1 340619704 10976261 4384766..4386145 1 NC_015844.1 The protein contains two domains. A N-terminal N-acetylmuramoyl-L-alanine amidase domain (230 residues) that hydrolyzes the amide bond between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell walls and a C-terminal domain (200 residues) of unknown function; Contains one N-terminal transmembrane segment; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family; Localized in the cytoplasmic membrane; High confidence in function and specificity; N-acetylmuramoyl-L-alanine amidase 4386145 amiA 10976261 amiA Zobellia galactanivorans N-acetylmuramoyl-L-alanine amidase YP_004738157.1 4384766 D 63186 CDS YP_004738158.1 340619705 10977518 4386246..4387226 1 NC_015844.1 Protein of unknown function that could be the periplasmic component of a ABC transporter (importer); Contains a Mce (mammalian cell entry) domain and one N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Conserved hypothetical protein; putative ABC transporter periplasmic 4387226 10977518 zobellia_3741 Zobellia galactanivorans putative ABC transporter periplasmic YP_004738158.1 4386246 D 63186 CDS YP_004738159.1 340619706 10976263 4387227..4388555 1 NC_015844.1 Membrane protein that could be the permease component of an ABC transporter (importer); Contains six N-terminal transmembrane segments; Localized in the cytoplasmic membrane; Specificity unclear; putative ABC transporter permease 4388555 10976263 zobellia_3742 Zobellia galactanivorans putative ABC transporter permease YP_004738159.1 4387227 D 63186 CDS YP_004738160.1 340619707 10976264 4388605..4389396 1 NC_015844.1 Protein that could be an oxidoreductase; Contains two cysteine-rich regions (CCG domains); Localized in the cytoplasm; Specificity unclear; putative oxidoreductase 4389396 10976264 zobellia_3743 Zobellia galactanivorans putative oxidoreductase YP_004738160.1 4388605 D 63186 CDS YP_004738161.1 340619708 10976265 4389436..4389918 1 NC_015844.1 Conserved hypothetical protein that could be an ATP-binding protein; Localized in the cytoplasm; Conserved hypothetical protein; putative ABC transporter ATPase 4389918 10976265 zobellia_3744 Zobellia galactanivorans putative ABC transporter ATPase YP_004738161.1 4389436 D 63186 CDS YP_004738162.1 340619709 10976266 4390026..4392935 1 NC_015844.1 This is a modular protein with a N-terminal beta-N-acetylglucosaminidase domain and a C-terminal serine peptidase domain. The beta-N-acetylglucosaminidase module belongs to the family 3 of the glycoside hydrolases. It catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides. The C-terminal domain belongs to the family 12 of the serine peptidases D-Ala-D-Ala carboxypeptidase B and aminopeptidase DmpB. Features a signal peptide cleaved between residues 19 and 20.; Specificity unclear; beta-N-acetylglucosaminidase 4392935 10976266 zobellia_3745 Zobellia galactanivorans beta-N-acetylglucosaminidase YP_004738162.1 4390026 D 63186 CDS YP_004738163.1 340619710 10976267 4393090..4394235 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; Belongs to the family 4 of the glycosyltransferases (GT4); Localized in the cytoplasm; Specificity unclear; glycosyltransferase 4394235 10976267 zobellia_3746 Zobellia galactanivorans glycosyltransferase YP_004738163.1 4393090 D 63186 CDS YP_004738164.1 340619711 10976268 4394237..4394680 1 NC_015844.1 Signal peptide of lipoprotein possibly cleaved between the residues 14 and 15; Localized in the cytoplasmic membrane; hypothetical protein 4394680 10976268 zobellia_3747 Zobellia galactanivorans hypothetical protein YP_004738164.1 4394237 D 63186 CDS YP_004738165.1 340619712 10976269 4394800..4395978 1 NC_015844.1 This conserved protein belongs to the OmpA-like family. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space and/or in the outer membrane; Family membership; OmpA-like periplasmic protein 4395978 10976269 zobellia_3748 Zobellia galactanivorans OmpA-like periplasmic protein YP_004738165.1 4394800 D 63186 CDS YP_004738166.1 340619713 10976270 complement(4395979..4398030) 1 NC_015844.1 Contains an N-terminal haloacid dehalogenase (HAD) domain; Localized in the cytoplasm; hypothetical protein 4398030 10976270 zobellia_3749 Zobellia galactanivorans hypothetical protein YP_004738166.1 4395979 R 63186 CDS YP_004738167.1 340619714 10976271 complement(4398331..4399512) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4399512 10976271 zobellia_3750 Zobellia galactanivorans hypothetical protein YP_004738167.1 4398331 R 63186 CDS YP_004738168.1 340619715 10976272 complement(4399548..4400519) 1 NC_015844.1 Contains one N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 4400519 10976272 zobellia_3751 Zobellia galactanivorans hypothetical protein YP_004738168.1 4399548 R 63186 CDS YP_004738169.1 340619716 10976273 complement(4400526..4401980) 1 NC_015844.1 Poly(beta-D-mannuronate) O-acetylase, involved in glycan biosynthesis, forms an cytoplasmic membrane complex which probably interacts with a beta-D-mannuronate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid; Contains ten transmembrane segments; Belongs to the MBOAT (membrane-bound acyltransferase) family; Specificity unclear; poly(beta-D-mannuronate) O-acetylase 4401980 algI1 10976273 algI1 Zobellia galactanivorans poly(beta-D-mannuronate) O-acetylase YP_004738169.1 4400526 R 63186 CDS YP_004738170.1 340619717 10977503 complement(4402041..4403285) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4403285 10977503 zobellia_3753 Zobellia galactanivorans hypothetical protein YP_004738170.1 4402041 R 63186 CDS YP_004738171.1 340619718 10976274 complement(4403298..4404347) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4404347 10976274 zobellia_3754 Zobellia galactanivorans hypothetical protein YP_004738171.1 4403298 R 63186 CDS YP_004738172.1 340619719 10976275 complement(4404675..4405331) 1 NC_015844.1 The hydrolases of the superfamily HAD (Haloacid dehalogenase) catalyse a nucleophilic displacement reaction, with water as the sole co-substrate. They are structurally different from the alpha/beta hydrolase family (abhydrolase); Belongs to the haloacid dehalogenase- like hydrolase superfamily; Localized in the cytoplasm; Family membership; hydrolase HAD superfamily 4405331 10976275 zobellia_3755 Zobellia galactanivorans hydrolase HAD superfamily YP_004738172.1 4404675 R 63186 CDS YP_004738173.1 340619720 10976276 complement(4405315..4406283) 1 NC_015844.1 The ATP-grasp proteins catalyze the Magnesium- and ATP-dependent ligation of a carboxylate containing molecule to an amino or thiol group-containing molecule. They contribute predominantly to macromolecular synthesis. ATP-hydrolysis is used to activate a substrate; Binds 3 manganese ions; Localized in the cytoplasm; Function unclear; ATP-grasp protein 4406283 10976276 zobellia_3756 Zobellia galactanivorans ATP-grasp protein YP_004738173.1 4405315 R 63186 CDS YP_004738174.1 340619721 10976277 complement(4406280..4407305) 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases. It is closely related to the beta-(1,4)-galactosyltransferase EspJ which is involved in the biosynthesis of exopolysaccharides in Lactobacillus delbrueckii.; High confidence in function and specificity; beta-(1,4)-galactosyltransferase 4407305 10976277 zobellia_3757 Zobellia galactanivorans beta-(1,4)-galactosyltransferase YP_004738174.1 4406280 R 63186 CDS YP_004738175.1 340619722 10976278 complement(4407296..4407874) 1 NC_015844.1 Conserved protein involved in exopolysaccharide biosynthesis. Its exact function is unknown. Contains a N-terminal transmembrane helix. Localized in the cytoplasmic membrane.; Function unclear; exopolysaccharide production protein 4407874 10976278 zobellia_3758 Zobellia galactanivorans exopolysaccharide production protein YP_004738175.1 4407296 R 63186 CDS YP_004738176.1 340619723 10976279 complement(4408188..4409333) 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. This enzyme is likely involved in the biosynthesis of exopolysaccharides. Localized in the cytoplasm.; Specificity unclear; capsular polysaccharide biosynthesis glycosyltransferase 4409333 capM 10976279 capM Zobellia galactanivorans capsular polysaccharide biosynthesis glycosyltransferase YP_004738176.1 4408188 R 63186 CDS YP_004738177.1 340619724 10977621 complement(4409383..4410522) 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Localized in the cytoplasm.; Specificity unclear; glycosyltransferase 4410522 10977621 zobellia_3760 Zobellia galactanivorans glycosyltransferase YP_004738177.1 4409383 R 63186 CDS YP_004738178.1 340619725 10976281 complement(4410545..4412395) 1 NC_015844.1 Asparagine synthase (glutamine-hdrolysing) catalyses the conversion of aspartate to asparagine from glutamine as amido-N-donor. Contains a N-terminal class-2 glutamine amidotransferase domain (GATase domain). Forms a homodimer. Localized in the cytoplasm.; High confidence in function and specificity; asparagine synthase B 4412395 asnB2 10976281 asnB2 Zobellia galactanivorans asparagine synthase B YP_004738178.1 4410545 R 63186 CDS YP_004738179.1 340619726 10977557 complement(4412566..4413639) 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Localized in the cytoplasm.; Specificity unclear; glycosyltransferase 4413639 10977557 zobellia_3762 Zobellia galactanivorans glycosyltransferase YP_004738179.1 4412566 R 63186 CDS YP_004738180.1 340619727 10976282 complement(4413731..4415587) 1 NC_015844.1 Asparagine synthase (glutamine-hydrolyzing) catalyses the conversion of aspartate to asparagine from glutamine as amido-N-donor. Contains a N-terminal class-2 glutamine amidotransferase domain and a helix-turn-hlix motive. Forms a homodimer. Localized in the cytoplasm.; High confidence in function and specificity; asparagine synthase B 4415587 asnB3 10976282 asnB3 Zobellia galactanivorans asparagine synthase B YP_004738180.1 4413731 R 63186 CDS YP_004738181.1 340619728 10977558 complement(4415684..4417411) 1 NC_015844.1 Protein that could contain an Asparagine synthase domain. However, the N-terminal class-II Glutamine amidotransferase domain is absent; Localized in the cytoplasm; hypothetical protein 4417411 10977558 zobellia_3764 Zobellia galactanivorans hypothetical protein YP_004738181.1 4415684 R 63186 CDS YP_004738182.1 340619729 10976283 complement(4417524..4418705) 1 NC_015844.1 Proteins possibly involved in the synthesis of lipopolysaccharide (LPS); Contains ten transmembrane segments and a C-terminal O-Antigen Polymerase domain; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4418705 10976283 zobellia_3765 Zobellia galactanivorans membrane protein YP_004738182.1 4417524 R 63186 CDS YP_004738183.1 340619730 10976284 complement(4418710..4419807) 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Localized in the cytoplasm; Specificity unclear; glycosyltransferase 4419807 10976284 zobellia_3766 Zobellia galactanivorans glycosyltransferase YP_004738183.1 4418710 R 63186 CDS YP_004738184.1 340619731 10976285 complement(4419885..4420778) 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases. Localized in the cytoplasm.; Specificity unclear; glycosyltransferase 4420778 10976285 zobellia_3767 Zobellia galactanivorans glycosyltransferase YP_004738184.1 4419885 R 63186 CDS YP_004738185.1 340619732 10976286 complement(4420949..4422487) 1 NC_015844.1 Membrane protein possibly involved in the export of O-antigen; Contains 11 transmembrane segments; Localized in the cytoplasmic membrane; Function unclear; membrane protein 4422487 10976286 zobellia_3768 Zobellia galactanivorans membrane protein YP_004738185.1 4420949 R 63186 CDS YP_004738186.1 340619733 10976287 complement(4422487..4423494) 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases. Closely related to genes involved in the biosynthesis of capsular exopolysaccharides in Firmicutes. Features a C-terminal transmembrane helix. Localized in the cytoplasmic membrane.; Family membership; glycosyltransferase 4423494 10976287 zobellia_3769 Zobellia galactanivorans glycosyltransferase YP_004738186.1 4422487 R 63186 CDS YP_004738187.1 340619734 10976288 complement(4423665..4425422) 1 NC_015844.1 Pectate lyase catalyzes the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends; Contains a N-terminal domain of unknown function; Belongs to the family 1 of the polysaccharide lyases (PL1); Lipoprotein signal peptide cleaved between the residues 23 and 24, Localized in the outer membrane; High confidence in function and specificity; pectate lyase, family PL1 4425422 pelA1 10976288 pelA1 Zobellia galactanivorans pectate lyase, family PL1 YP_004738187.1 4423665 R 63186 CDS YP_004738188.1 340619735 10978323 complement(4425849..4427129) 1 NC_015844.1 VipA is involved in the biosynthesis of an exopolysaccharide. In Salmonella typhi, this EPS is the Vi antigen. VipA belongs to the UDP-glucose/GDP-mannose dehydrogenase family, a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate. Localized in the cytoplasm.; High confidence in function and specificity; Vi polysaccharide biosynthesis protein vipA 4427129 vipA 10978323 vipA Zobellia galactanivorans Vi polysaccharide biosynthesis protein vipA YP_004738188.1 4425849 R 63186 CDS YP_004738189.1 340619736 10978744 complement(4427136..4428134) 1 NC_015844.1 UDP-N-acetylglucosamine 4-epimerase converts the UDP-N-acetyl-D-glucosamine to UDP-N-acetyl-D-galactosamine. WbpP is involved in the nucleotide sugar metabolism and in the lipopolysaccharide biosynthesis; Belongs to the NAD dependent epimerase/dehydratase family, Rossmann fold Superfamily; Localized in the cytoplasm; High confidence in function and specificity; UDP-N-acetylglucosamine 4-epimerase 4428134 wbpP 10978744 wbpP Zobellia galactanivorans UDP-N-acetylglucosamine 4-epimerase YP_004738189.1 4427136 R 63186 CDS YP_004738190.1 340619737 10978752 complement(4428380..4429489) 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4429489 10978752 zobellia_3773 Zobellia galactanivorans membrane protein YP_004738190.1 4428380 R 63186 CDS YP_004738191.1 340619738 10976290 complement(4429750..4431837) 1 NC_015844.1 Modular protein with a N-terminal TolA-like domain and a C-terminal pectate lyase domain. Pectate lyase catalyzes the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. The catalytic domain belongs to the family 1 of the polysaccharide lyases (PL1). Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; High confidence in function and specificity; pectate lyase, family PL1 4431837 pelA2 10976290 pelA2 Zobellia galactanivorans pectate lyase, family PL1 YP_004738191.1 4429750 R 63186 CDS YP_004738192.1 340619739 10978324 4432302..4433786 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4433786 10978324 zobellia_3775 Zobellia galactanivorans membrane protein YP_004738192.1 4432302 D 63186 CDS YP_004738193.1 340619740 10976291 complement(4433827..4434729) 1 NC_015844.1 Contains one N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 4434729 10976291 zobellia_3776 Zobellia galactanivorans hypothetical protein YP_004738193.1 4433827 R 63186 CDS YP_004738194.1 340619741 10976292 complement(4434733..4436175) 1 NC_015844.1 Poly(beta-D-mannuronate) O-acetylase, involved in glycan biosynthesis, forms an cytoplasmic membrane complex which probably interacts with a beta-D-mannuronate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid; Contains 8 transmembrane segments; Belongs to the MBOAT (membrane-bound acyltransferase) family; Localized in the cytoplasmic membrane; Specificity unclear; poly(beta-D-mannuronate) O-acetylase 4436175 algI2 10976292 algI2 Zobellia galactanivorans poly(beta-D-mannuronate) O-acetylase YP_004738194.1 4434733 R 63186 CDS YP_004738195.1 340619742 10977504 complement(4436292..4437308) 1 NC_015844.1 UDP-glucuronate 4-epimerase converts the UDP-glucuronate to UDP-D-galacturonate. LpsL is involved in lipopolysaccharide biosynthesis; Belongs to the NAD dependent epimerase/dehydratase family, Rossmann fold Superfamily; Localized in the cytoplasmic membrane; High confidence in function and specificity; UDP-glucuronate 4-epimerase 4437308 lpsL 10977504 lpsL Zobellia galactanivorans UDP-glucuronate 4-epimerase YP_004738195.1 4436292 R 63186 CDS YP_004738196.1 340619743 10978101 complement(4437305..4438714) 1 NC_015844.1 UDP-glucose 6-dehydrogenase catalyzes the oxidation of UDP-glucose to UDP-glucuronate . Likely involves in EPS biosynthesis. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family, a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate; Localized in the cytoplasm; High confidence in function and specificity; UDP-glucose 6-dehydrogenase 4438714 ugdH 10978101 ugdH Zobellia galactanivorans UDP-glucose 6-dehydrogenase YP_004738196.1 4437305 R 63186 CDS YP_004738197.1 340619744 10978723 4439096..4440091 1 NC_015844.1 UDP-glucuronic acid decarboxylase converts the UDP-D-glucuronic acid to UDP-D-xylose and CO2. This enzyme is involved in the nucleotide sugar metabolism; Belongs to the NAD dependent epimerase/dehydratase family, Rossmann fold Superfamily; Localized in the cytoplasm; High confidence in function and specificity; UDP-glucuronic acid decarboxylase 4440091 10978723 zobellia_3780 Zobellia galactanivorans UDP-glucuronic acid decarboxylase YP_004738197.1 4439096 D 63186 CDS YP_004738198.1 340619745 10976294 complement(4440365..4440568) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4440568 10976294 zobellia_3781 Zobellia galactanivorans hypothetical protein YP_004738198.1 4440365 R 63186 CDS YP_004738199.1 340619746 10976295 4440656..4441624 1 NC_015844.1 This enzyme belongs to pyridoxal-phosphate (PLP)-dependent aminotransferase superfamily, DegT/DnrJ/EryC1/StrS aminotransferase family; Localized in the cytoplasm; Specificity unclear; PLP-dependent aminotransferase 4441624 10976295 zobellia_3782 Zobellia galactanivorans PLP-dependent aminotransferase YP_004738199.1 4440656 D 63186 CDS YP_004738200.1 340619747 10976296 4441629..4443560 1 NC_015844.1 CapD is involved in EPS/LPS biosynthesis. Its exact function is unknown; Contains five transmembrane helices; Localized in the cytoplasmic membrane; Function unclear; polysaccharide biosynthesis protein CapD 4443560 capD 10976296 capD Zobellia galactanivorans polysaccharide biosynthesis protein CapD YP_004738200.1 4441629 D 63186 CDS YP_004738201.1 340619748 10977619 4443601..4444401 1 NC_015844.1 This membrane protein is likely involved in the export of expolysaccharide repeating units from the cytoplasm into the periplasm in a process analogous to O-unit export; Contains a C-terminal transmembrane helix; lipoprotein signal peptide cleaved between the residues 31 and 32; Localized in the cytoplasmic membrane; Specificity unclear; polysaccharide export protein 4444401 10977619 zobellia_3784 Zobellia galactanivorans polysaccharide export protein YP_004738201.1 4443601 D 63186 CDS YP_004738202.1 340619749 10976297 4444435..4446816 1 NC_015844.1 May be involved in the production and the transport of exopolysaccharides; Contains a N-terminal and a central transmembrane segment; Putatively autophosphorylated on several Tyr residues; Belongs to the etk/wzc family; Localized in the cytoplasmic membrane; Specificity unclear; tyrosine-protein kinase 4446816 ptkA 10976297 ptkA Zobellia galactanivorans tyrosine-protein kinase YP_004738202.1 4444435 D 63186 CDS YP_004738203.1 340619750 10978396 4447193..4453312 1 NC_015844.1 The mature protein is a multidomain protein: The first 430 residues would be The signal peptide is cleaved between the residues 26 and 27; Protein probably localized in the outer membrane; Hypothetical protein; quinoprotein glucose dehydrogenase 4453312 gdhB2 10978396 gdhB2 Zobellia galactanivorans quinoprotein glucose dehydrogenase YP_004738203.1 4447193 D 63186 CDS YP_004738204.1 340619751 10977889 complement(4453402..4454142) 1 NC_015844.1 Dephosphorylates the phosphotyrosine-containing proteins required for the biosynthesis of type 1 capsular polysaccharide; Involved in the capsular polysaccharide (CPS) biosynthesis; Uses the mamganese as cofactor; Contains a polymerase and histidinol Phosphatase domain (PHP domain; Localized in the cytoplasm; High confidence in function and specificity; tyrosine-protein phosphatase 4454142 capC 10977889 capC Zobellia galactanivorans tyrosine-protein phosphatase YP_004738204.1 4453402 R 63186 CDS YP_004738205.1 340619752 10977618 complement(4454339..4456570) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-97) and the Plug module (109-219) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 4456570 10977618 zobellia_3788 Zobellia galactanivorans TonB-dependent Receptor YP_004738205.1 4454339 R 63186 CDS YP_004738206.1 340619753 10976298 complement(4456675..4457151) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4457151 10976298 zobellia_3789 Zobellia galactanivorans hypothetical protein YP_004738206.1 4456675 R 63186 CDS YP_004738207.1 340619754 10976299 complement(4457236..4457376) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4457376 10976299 zobellia_3790 Zobellia galactanivorans hypothetical protein YP_004738207.1 4457236 R 63186 CDS YP_004738208.1 340619755 10976301 complement(4457692..4459047) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4459047 10976301 zobellia_3791 Zobellia galactanivorans hypothetical protein YP_004738208.1 4457692 R 63186 CDS YP_004738209.1 340619756 10976302 complement(4459010..4459222) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 4459222 10976302 zobellia_3792 Zobellia galactanivorans hypothetical protein YP_004738209.1 4459010 R 63186 CDS YP_004738210.1 340619757 10976303 complement(4459219..4460115) 1 NC_015844.1 ApbE is involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine (HMP) moiety of thiamine. Localized in the cytoplasm.; High confidence in function and specificity; thiamine biosynthesis protein apbE 4460115 apbE3 10976303 apbE3 Zobellia galactanivorans thiamine biosynthesis protein apbE YP_004738210.1 4459219 R 63186 CDS YP_004738211.1 340619758 10977525 complement(4460309..4461337) 1 NC_015844.1 NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold. Localized in the cytoplasm.; Specificity unclear; NAD(P)-dependent oxidoreductase 4461337 10977525 zobellia_3794 Zobellia galactanivorans NAD(P)-dependent oxidoreductase YP_004738211.1 4460309 R 63186 CDS YP_004738212.1 340619759 10976304 complement(4461339..4462607) 1 NC_015844.1 The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients; Contains 11 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; major facilitator family transporter 4462607 10976304 zobellia_3795 Zobellia galactanivorans major facilitator family transporter YP_004738212.1 4461339 R 63186 CDS YP_004738213.1 340619760 10976305 complement(4462617..4464002) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4464002 10976305 zobellia_3796 Zobellia galactanivorans hypothetical protein YP_004738213.1 4462617 R 63186 CDS YP_004738214.1 340619761 10976306 complement(4464002..4464646) 1 NC_015844.1 Conserved protein belonging to a family of putative cyclases. These proteins contain a conserved motif HXGTHXDXPXH that is likely to form part of the active site. Localized in the cytoplasm.; hypothetical protein 4464646 10976306 zobellia_3797 Zobellia galactanivorans hypothetical protein YP_004738214.1 4464002 R 63186 CDS YP_004738215.1 340619762 10976307 complement(4464661..4465725) 1 NC_015844.1 Tartrate dehydrogenase/decarboxylase has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate. It uses NAD+ as a cofactor. Belongs to the Isocitrate dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity; Tartrate dehydrogenase/decarboxylase 4465725 ttuC 10976307 ttuC Zobellia galactanivorans Tartrate dehydrogenase/decarboxylase YP_004738215.1 4464661 R 63186 CDS YP_004738216.1 340619763 10978714 4465825..4466937 1 NC_015844.1 The LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of operons; They contain a N-terminal lacI-type HTH domain involved in the binding of the protein to the operator sequences in the DNA and a C- terminal periplasmic binding protein domain that are the primary receptors for chemotaxis and transport of many sugar based solutes that act as inducers; Localized in the cytoplasm; Family membership; LacI-type transcriptional regulator 4466937 10978714 zobellia_3799 Zobellia galactanivorans LacI-type transcriptional regulator YP_004738216.1 4465825 D 63186 CDS YP_004738217.1 340619764 10976308 4466990..4469950 1 NC_015844.1 Could be a possible enzyme acting with carbohydrates; Contains a signal peptide cleaved between the residues 30 and 31; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4469950 10976308 zobellia_3800 Zobellia galactanivorans periplasmic protein YP_004738217.1 4466990 D 63186 CDS YP_004738218.1 340619765 10976311 4469958..4470803 1 NC_015844.1 Protein that contains a domain of unknown function DUF1080; Putative lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 4470803 10976311 zobellia_3801 Zobellia galactanivorans membrane protein YP_004738218.1 4469958 D 63186 CDS YP_004738219.1 340619766 10976312 complement(4470855..4472420) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 27; Lipoprotein with a signal peptide cleaved between the residues 15 and 16; Localized in the outer membrane; Family membership; sulfatase 4472420 10976312 zobellia_3802 Zobellia galactanivorans sulfatase YP_004738219.1 4470855 R 63186 CDS YP_004738220.1 340619767 10976313 complement(4472436..4474004) 1 NC_015844.1 This conserved protein likely adopts a right handed parallel beta-helix fold; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Function unclear; beta-helix fold protein 4474004 10976313 zobellia_3803 Zobellia galactanivorans beta-helix fold protein YP_004738220.1 4472436 R 63186 CDS YP_004738221.1 340619768 10976314 complement(4473994..4475217) 1 NC_015844.1 Unsaturated glucuronyl hydrolase is involved in the catabolism of unsaturated oligosaccharides produced by polysaccharide lyases. UglA catalyzes the hydrolysis of oligosaccharides with unsaturated uronic acids at the nonreducing terminal, to a sugar or an amino sugar, and an unsaturated uronic acid, which is nonenzymatically converted immediately to alpha-keto acid; Belongs to the family 88 of the glycoside hydrolases (GH88); Signal peptide cleaved between residues 22 and 23; Localized in the periplasmic space; Specificity unclear; unsaturated glucuronyl hydrolase 4475217 uglA2 10976314 uglA2 Zobellia galactanivorans unsaturated glucuronyl hydrolase YP_004738221.1 4473994 R 63186 CDS YP_004738222.1 340619770 10978725 complement(4475357..4479451) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 4479451 10978725 zobellia_3806 Zobellia galactanivorans one-component system sensor protein YP_004738222.1 4475357 R 63186 CDS YP_004738223.1 340619769 10976316 4479440..4479640 1 NC_015844.1 Hypothetical protein; hypothetical protein 4479640 10976316 zobellia_3805 Zobellia galactanivorans hypothetical protein YP_004738223.1 4479440 D 63186 CDS YP_004738224.1 340619771 10976315 4479647..4480486 1 NC_015844.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase catalyzes the reaction is involved in pectin degradation in pectinolytic microorganism; Localized in the cytoplasm; High confidence in function and specificity; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase 4480486 kduI4 10976315 kduI4 Zobellia galactanivorans 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase YP_004738224.1 4479647 D 63186 CDS YP_004738225.1 340619772 10978065 4480489..4481283 1 NC_015844.1 Also called 5-keto-D-gluconate 5-reductase. Catalyzes the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate using NADP as a coenzyme. Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity; gluconate-5-dehydrogenase 4481283 idnO2 10978065 idnO2 Zobellia galactanivorans gluconate-5-dehydrogenase YP_004738225.1 4480489 D 63186 CDS YP_004738226.1 340619773 10978021 4481288..4482484 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4482484 10978021 zobellia_3809 Zobellia galactanivorans hypothetical protein YP_004738226.1 4481288 D 63186 CDS YP_004738227.1 340619774 10976317 complement(4482539..4483111) 1 NC_015844.1 Maltose O-acetyltransferase converts the maltose to acetyl-maltose from acetyl-CoA. Maltose O-acetyltransferase is a homodimer, responsible for exit of maltose and glucose in their acetylated forms; Localized in the cytoplasm; High confidence in function and specificity; maltose O-acetyltransferase 4483111 maaA2 10976317 maaA2 Zobellia galactanivorans maltose O-acetyltransferase YP_004738227.1 4482539 R 63186 CDS YP_004738228.1 340619775 10978115 complement(4483180..4483662) 1 NC_015844.1 Guanine deaminase catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia . Expressed only during limited or partially limited nitrogen conditions. Can be induced to high levels in the presence of purines or intermediates of the purine catabolic pathway. GuaD adopts an alpha/beta/alpha three- layered fold and forms a homodimer. The essential zinc ion is ligated by a water molecule together with conserved residues, one histidine and two cysteine. Belongs to the cytidine and deoxycytidylate deaminase family. Localized in the cytoplasm.; High confidence in function and specificity; Guanine deaminase 4483662 guaD 10978115 guaD Zobellia galactanivorans Guanine deaminase YP_004738228.1 4483180 R 63186 CDS YP_004738229.1 340619776 10977956 4484050..4486812 1 NC_015844.1 Protein that consists of an N-terminal periplasmic beta-propeller followed by a C-terminal cytoplasmic domain containing a LuxR-type HTH domain acting as transcrptionnal regulator. A transmembrane segment is present between these two domains. Signal peptide cleaved between the residues 22 and 23; Localized in the cytoplasmic membrane; Family membership; ligand-binding sensor protein 4486812 10977956 zobellia_3812 Zobellia galactanivorans ligand-binding sensor protein YP_004738229.1 4484050 D 63186 CDS YP_004738230.1 340619777 10976319 4487077..4490115 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (25-99) and the Plug module (115-222) acting as a channel gate; The signal peptide is cleaved between the residues 21 and 22; Family membership; TonB-dependent Receptor 4490115 10976319 zobellia_3813 Zobellia galactanivorans TonB-dependent Receptor YP_004738230.1 4487077 D 63186 CDS YP_004738231.1 340619778 10976320 4490128..4491666 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 4491666 10976320 zobellia_3814 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004738231.1 4490128 D 63186 CDS YP_004738232.1 340619779 10976321 4491692..4493488 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4493488 10976321 zobellia_3815 Zobellia galactanivorans hypothetical protein YP_004738232.1 4491692 D 63186 CDS YP_004738233.1 340619780 10976322 4493530..4494888 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 4494888 10976322 zobellia_3816 Zobellia galactanivorans hypothetical protein YP_004738233.1 4493530 D 63186 CDS YP_004738234.1 340619781 10976323 4494878..4496266 1 NC_015844.1 Contains a signal peptide cleaved between the residiues 17 and 18; Probably localized in the outer membrane; Conserved hypothetical protein; membrane lipoprotein 4496266 10976323 zobellia_3817 Zobellia galactanivorans membrane lipoprotein YP_004738234.1 4494878 D 63186 CDS YP_004738235.1 340619782 10976324 4496377..4498650 1 NC_015844.1 BglX catalyzes the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose. Belongs to the family 3 of the glycoside hydrolases (GH3); Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; High confidence in function and specificity; beta-glucosidase 4498650 bglX 10976324 bglX Zobellia galactanivorans beta-glucosidase YP_004738235.1 4496377 D 63186 CDS YP_004738236.1 340619783 10977601 4498667..4500301 1 NC_015844.1 Mucin-desulfating sulfatases hydrolyse the sulfate groups from oligosaccharides present in mucins (heavily glycosylated proteins). In the mucins, the main sulfated sugars are N-acetyl-D-glucosamine-6-sulfate, galactose-6-sulfate and galactose-3-sulfate; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 11; Putative lipoprotein with a signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Specificity unclear; mucin-desulfating sulfatase 4500301 mdsA6 10977601 mdsA6 Zobellia galactanivorans mucin-desulfating sulfatase YP_004738236.1 4498667 D 63186 CDS YP_004738237.1 340619784 10978137 4500419..4503925 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4503925 10978137 zobellia_3820 Zobellia galactanivorans periplasmic protein YP_004738237.1 4500419 D 63186 CDS YP_004738238.1 340619785 10976326 4503944..4505557 1 NC_015844.1 Conserved protein containing a N-terminal Rieske [2Fe-2S] domain and a C-terminal domain Localized in the cytoplasm; Conserved hypothetical protein; FMN / Fe-S cluster binding protein 4505557 10976326 zobellia_3821 Zobellia galactanivorans FMN / Fe-S cluster binding protein YP_004738238.1 4503944 D 63186 CDS YP_004738239.1 340619786 10976327 4505568..4506302 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 4506302 10976327 zobellia_3822 Zobellia galactanivorans hypothetical protein YP_004738239.1 4505568 D 63186 CDS YP_004738240.1 340619787 10976328 4506305..4506958 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4506958 10976328 zobellia_3823 Zobellia galactanivorans hypothetical protein YP_004738240.1 4506305 D 63186 CDS YP_004738241.1 340619788 10976329 4506965..4507588 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4507588 10976329 zobellia_3824 Zobellia galactanivorans membrane protein YP_004738241.1 4506965 D 63186 CDS YP_004738242.1 340619789 10976330 complement(4507585..4507944) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4507944 10976330 zobellia_3825 Zobellia galactanivorans hypothetical protein YP_004738242.1 4507585 R 63186 CDS YP_004738243.1 340619790 10976331 4508174..4509619 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Putative lipoprotein with a signal peptide cleaved between the residues 17 and 18; Localized in the outer membrane; Family membership; sulfatase 4509619 10976331 zobellia_3826 Zobellia galactanivorans sulfatase YP_004738243.1 4508174 D 63186 CDS YP_004738244.1 340619791 10976332 complement(4509630..4510298) 1 NC_015844.1 Protein that consists of a SCO1/SenC domain; Contains a N-terminal transmembrane segment; Belongs to the SCO2/SenC family; Localized in the cytoplasmic membrane; Family membership; membrane protein 4510298 10976332 zobellia_3827 Zobellia galactanivorans membrane protein YP_004738244.1 4509630 R 63186 CDS YP_004738245.1 340619792 10976333 complement(4510807..4512162) 1 NC_015844.1 Lipoprotein with a signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4512162 10976333 zobellia_3828 Zobellia galactanivorans lipoprotein YP_004738245.1 4510807 R 63186 CDS YP_004738246.1 340619793 10976334 complement(4512416..4513534) 1 NC_015844.1 The beta chain of DNA polymerase III is the processivity factor required for initiation of replication from an RNA primer, once it is clamped onto DNA. It slides freely (bidirectional and ATP-independent) along duplex DNA; The DNA polymerase III or replicase is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The DNA polymerase III also exhibits a 3' to 5' exonuclease proofreading activity; Localized in the cytoplasm; High confidence in function and specificity; DNA polymerase III subunit beta 4513534 dnaN 10976334 dnaN Zobellia galactanivorans DNA polymerase III subunit beta YP_004738246.1 4512416 R 63186 CDS YP_004738247.1 340619794 10977755 complement(4513665..4515335) 1 NC_015844.1 Membrane protein involved in the gliding motility; Ccontains a C-terminal transmembrane segment; Signal peptide cleaved between the residues 23 and 24; Localized in the cytoplasmic membrane; Function unclear; gliding motility membrane protein 4515335 gldG 10977755 gldG Zobellia galactanivorans gliding motility membrane protein YP_004738247.1 4513665 R 63186 CDS YP_004738248.1 340619795 10977904 complement(4515335..4516066) 1 NC_015844.1 Belongs to Type 2 ABC (ATP-binding cassette) transporter, permease domain (ABC membrane); Involved in the gliding motility; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Specificity unclear; gliding motility permease, ABC-2 type exporter 4516066 gldF 10977904 gldF Zobellia galactanivorans gliding motility permease, ABC-2 type exporter YP_004738248.1 4515335 R 63186 CDS YP_004738249.1 340619796 10977903 complement(4516235..4517068) 1 NC_015844.1 Contains the conserved domain DUF62; Probably localized in the cytoplasm; hypothetical protein 4517068 10977903 zobellia_3832 Zobellia galactanivorans hypothetical protein YP_004738249.1 4516235 R 63186 CDS YP_004738250.1 340619797 10976335 4517359..4518312 1 NC_015844.1 PhoH is induced by phosphate starvation. It has an ATP-binding activity in vitro and is predicted to be a ATPase. Localized in the cytoplasm.; Function unclear; protein PhoH 4518312 phoH 10976335 phoH Zobellia galactanivorans protein PhoH YP_004738250.1 4517359 D 63186 CDS YP_004738251.1 340619798 10978350 4518351..4519301 1 NC_015844.1 Phosphoribosylaminoimidazole-succinocarboxamide synthase catalyzes the seventh step in the de novo purine biosynthetic pathway: the ATP-dependent conversion of 5'-phosphoribosyl-5-aminoimidazole-4-carboxylic acid and aspartic acid to SAICAR. It forms a homotrimer. Localized in the cytoplasm.; High confidence in function and specificity; phosphoribosylaminoimidazole-succinocarboxamide synthase 4519301 purC 10978350 purC Zobellia galactanivorans phosphoribosylaminoimidazole-succinocarboxamide synthase YP_004738251.1 4518351 D 63186 CDS YP_004738252.1 340619799 10978405 complement(4519306..4519962) 1 NC_015844.1 The epsilon subunit of DNA polymerase III is responsible of the proofreading 3'-5' exonuclease activity; The DNA polymerase III or replicase is responsible for most of the replicative synthesis in bacteria. It exhibits a DNA polymerase activity (alpha chain) and a 3' to 5' exonuclease proofreading activity; Localized in the cytoplasm; High confidence in function and specificity; DNA polymerase III subunit epsilon 4519962 dnaQ 10978405 dnaQ Zobellia galactanivorans DNA polymerase III subunit epsilon YP_004738252.1 4519306 R 63186 CDS YP_004738253.1 340619800 10977756 complement(4519962..4521887) 1 NC_015844.1 Conserved protein containing a N-terminal cyclic nucleotide-binding domain, a central CBS domain and a C-terminal DUF294 family domain. The cyclic nucleotide-binding domains are composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure. CBS (cystathionine-beta-synthase) domains are small intracellular modules that pair together to form a stable globular domain. They bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet and may play a regulatory role making proteins sensitive to adenosyl carrying ligands. DUF294 family proteins are found associated to CBS domains and are predicted as nucleotidyltransferases. Localized in the cytoplasm.; Function unclear; cyclic nucleotide-binding protein 4521887 10977756 zobellia_3836 Zobellia galactanivorans cyclic nucleotide-binding protein YP_004738253.1 4519962 R 63186 CDS YP_004738254.1 340619802 10976336 complement(4521960..4522058) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4522058 10976336 zobellia_3838 Zobellia galactanivorans hypothetical protein YP_004738254.1 4521960 R 63186 CDS YP_004738255.1 340619801 10976338 4522057..4524297 1 NC_015844.1 Conserved protein belonging to the DUF893 family; Contains nine transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4524297 10976338 zobellia_3837 Zobellia galactanivorans membrane protein YP_004738255.1 4522057 D 63186 CDS YP_004738256.1 340619803 10976337 4524420..4524854 1 NC_015844.1 Heat shock protein acts as chaperone that can protect other proteins against heat-induced denaturation and aggregation; Belongs to the HSP20 family. Hsp20 proteins seem to form large heterooligomeric aggregates; Localized in the cytoplasm; Family membership; small heat shock protein 4524854 10976337 zobellia_3839 Zobellia galactanivorans small heat shock protein YP_004738256.1 4524420 D 63186 CDS YP_004738257.1 340619804 10976339 complement(4524939..4525031) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4525031 10976339 zobellia_3840 Zobellia galactanivorans hypothetical protein YP_004738257.1 4524939 R 63186 CDS YP_004738258.1 340619805 10976341 4525168..4525758 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4525758 10976341 zobellia_3841 Zobellia galactanivorans hypothetical protein YP_004738258.1 4525168 D 63186 CDS YP_004738259.1 340619806 10976342 4525810..4527246 1 NC_015844.1 Cardiolipin synthetase is involved in phospholipids biosynthesis. It catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (diphosphatidylglycerol) and glycerol; Contains two N-terminal transmembrane helices; Belongs to the phospholipase D family; Localized in the cytoplasmic membrane.; High confidence in function and specificity; cardiolipin synthetase 4527246 clsA2 10976342 clsA2 Zobellia galactanivorans cardiolipin synthetase YP_004738259.1 4525810 D 63186 CDS YP_004738260.1 340619807 10977658 4527318..4528094 1 NC_015844.1 Conserved protein belonging to the Patatin-like phospholipase family; Localized in the cytoplasm; Family membership; Patatin-like phospholipase 4528094 10977658 zobellia_3843 Zobellia galactanivorans Patatin-like phospholipase YP_004738260.1 4527318 D 63186 CDS YP_004738261.1 340619808 10976343 4528335..4531613 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It autophosphorylates a conserved histidine in its phosphoacceptor domain and phosphorylates the receiver domain of response regulator; Contains three N-terminal PAS/PAC domains and a GAF domain is present in the central part of the protein. The Histidine kinase domain is localized in the C-terminal end; Seems localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 4531613 10976343 zobellia_3844 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738261.1 4528335 D 63186 CDS YP_004738262.1 340619809 10976344 4531591..4532658 1 NC_015844.1 The response regulators are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of a N-terminal receiver domain that is substrate for a histidine protein kinase sensor, a cyclic nucleotide-binding domain and a C-terminal Crp-type HTH domain (effector domain); The Crp-type HTH domain binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; Specificity unclear; cyclic nucleotide-binding dependent two-component system-response regulator 4532658 10976344 zobellia_3845 Zobellia galactanivorans cyclic nucleotide-binding dependent two-component system-response regulator YP_004738262.1 4531591 D 63186 CDS YP_004738263.1 340619810 10976345 complement(4532678..4532908) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4532908 10976345 zobellia_3846 Zobellia galactanivorans hypothetical protein YP_004738263.1 4532678 R 63186 CDS YP_004738264.1 340619811 10976346 complement(4532905..4533255) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4533255 10976346 zobellia_3847 Zobellia galactanivorans membrane protein YP_004738264.1 4532905 R 63186 CDS YP_004738265.1 340619812 10976347 complement(4533262..4533591) 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4533591 10976347 zobellia_3848 Zobellia galactanivorans membrane protein YP_004738265.1 4533262 R 63186 CDS YP_004738266.1 340619813 10976348 4533753..4534256 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 4534256 10976348 zobellia_3849 Zobellia galactanivorans hypothetical protein YP_004738266.1 4533753 D 63186 CDS YP_004738267.1 340619814 10976349 4534348..4535118 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4535118 10976349 zobellia_3850 Zobellia galactanivorans hypothetical protein YP_004738267.1 4534348 D 63186 CDS YP_004738268.1 340619815 10976351 4535205..4535612 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4535612 10976351 zobellia_3851 Zobellia galactanivorans hypothetical protein YP_004738268.1 4535205 D 63186 CDS YP_004738269.1 340619816 10976352 complement(4535827..4537026) 1 NC_015844.1 ABC-2 Type (ATP-binding cassette) transporter, membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 4537026 10976352 zobellia_3852 Zobellia galactanivorans ABC transporter permease YP_004738269.1 4535827 R 63186 CDS YP_004738270.1 340619817 10976353 complement(4537023..4538210) 1 NC_015844.1 ABC-2 Type (ATP-binding cassette) transporter, membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 4538210 10976353 zobellia_3853 Zobellia galactanivorans ABC transporter permease YP_004738270.1 4537023 R 63186 CDS YP_004738271.1 340619818 10976354 complement(4538215..4539189) 1 NC_015844.1 These membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics, solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmique membrane by a N-terminal transmembrane region; Belongs to the type I secretion system; Family membership; membrane fusion protein 4539189 10976354 zobellia_3854 Zobellia galactanivorans membrane fusion protein YP_004738271.1 4538215 R 63186 CDS YP_004738272.1 340619819 10976355 complement(4539197..4540675) 1 NC_015844.1 The outer membrane efflux proteins (OEP) are composed of two repeats of OEP domain to form a trimeric channel continuous, solvent-accessible conduit that spans both the outer membrane and periplasmic space; May be specialized for the signal peptide independent extracellular secretion of a variety of substrates in Gram-negative bacteria (type I secretion system); Signal peptide cleaved between the residues 30 and 31; Localized in the outer membrane; Family membership; outer membrane efflux protein 4540675 10976355 zobellia_3855 Zobellia galactanivorans outer membrane efflux protein YP_004738272.1 4539197 R 63186 CDS YP_004738273.1 340619820 10976356 complement(4540776..4542047) 1 NC_015844.1 Membrane protein of unknown function probably acting as accessory protein to an ABC transporter; Contains an N-terminal MgtC domain and 12 transmembrane segments; Belongs to the MgtC/SapB family; Localized in the cytoplasmic membrane; Function unclear; multi-pass membrane transporter 4542047 10976356 zobellia_3856 Zobellia galactanivorans multi-pass membrane transporter YP_004738273.1 4540776 R 63186 CDS YP_004738274.1 340619821 10976357 complement(4542077..4543759) 1 NC_015844.1 The function of this protein is not clear. The UbiB (or AarF) protein is involved, probably indirectly, in the first hydoxylation step in respiratory cofactor ubiquinone (coenzyme Q) biosynthesis. Although it is not known if it has protein kinase activity and what substrate it would phosphorylate (Ser, Thr or Tyr), UbiB could play a role in ubiquinone biosynthesis-activating proteins necessary for the hydroxylase step(s) via phosphorylation; contains a protein kinase domain and two transmembrane segments; Belongs to the protein kinase superfamily, ADCK (ABC1/AarF domain containing kinase) family; Localized in the cytoplasmic membrane; Function unclear; putative ubiquinone biosynthesis protein UbiB 4543759 ubiB 10976357 ubiB Zobellia galactanivorans putative ubiquinone biosynthesis protein UbiB YP_004738274.1 4542077 R 63186 CDS YP_004738275.1 340619822 10978720 complement(4543774..4544160) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4544160 10978720 zobellia_3858 Zobellia galactanivorans hypothetical protein YP_004738275.1 4543774 R 63186 CDS YP_004738276.1 340619823 10976358 complement(4544337..4546334) 1 NC_015844.1 ATP-dependent metalloprotease mediates degradation of non-assembled cytoplasmic membrane proteins. It is necessary for the assembly of respiratory chain and ATPase complexes. Function both in post-translational assembly and in the turnover of mistranslated or misfolded polypeptides; Binds 1 zinc ion; Contains two N-terminal transmembrane segments; belongs, in the N-terminal part, to the AAA ATPase family and, in the C-terminal part, to the peptidase M41 family (clan MA(E)); Localized in the cytpolasmic membrane; High confidence in function and specificity; respiratory chain complexes assembly ATP-dependent metalloprotease 4546334 rcaA 10976358 rcaA Zobellia galactanivorans respiratory chain complexes assembly ATP-dependent metalloprotease YP_004738276.1 4544337 R 63186 CDS YP_004738277.1 340619824 10978437 complement(4546336..4546683) 1 NC_015844.1 Conserved protein belonging to the carboxymuconolactone decarboxylase family. Its exact function is not known. Localized in the cytoplasm.; Family membership; carboxymuconolactone decarboxylase family protein 4546683 10978437 zobellia_3860 Zobellia galactanivorans carboxymuconolactone decarboxylase family protein YP_004738277.1 4546336 R 63186 CDS YP_004738278.1 340619825 10976360 4546986..4547639 1 NC_015844.1 Could contain a an uncleavable N-terminal signal sequence; Putatively localized in the cytoplasmic membrane; hypothetical protein 4547639 10976360 zobellia_3861 Zobellia galactanivorans hypothetical protein YP_004738278.1 4546986 D 63186 CDS YP_004738279.1 340619826 10976361 4547784..4548569 1 NC_015844.1 Stress protein probably induced when the cell is exposed to stress agents or when conditions cause growth arrest; Contains two copies of the universal stress protein (usp) domain; Belongs to the Usp family. Members of the Usp family are predicted to be related to the MADS- box proteins and bind to DNA; Localized in the cytoplasm; Family membership; universal stress protein 4548569 10976361 zobellia_3862 Zobellia galactanivorans universal stress protein YP_004738279.1 4547784 D 63186 CDS YP_004738280.1 340619827 10976362 4548627..4549058 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4549058 10976362 zobellia_3863 Zobellia galactanivorans hypothetical protein YP_004738280.1 4548627 D 63186 CDS YP_004738281.1 340619828 10976363 complement(4549120..4550193) 1 NC_015844.1 Glucokinase is involved in the first step of the glycolysis (Embden-Meyerhof pathway). It phosphoryles the D-glucose to D-glucose 6-phosphate. This reaction consumes ATP, but it acts to keep the glucose concentration low, promoting continuous transport of glucose into the cell through the cytoplasmic membrane transporters; Localized in the cytoplasm; High confidence in function and specificity; glucokinase 4550193 glkA 10976363 glkA Zobellia galactanivorans glucokinase YP_004738281.1 4549120 R 63186 CDS YP_004738282.1 340619829 10977914 complement(4550211..4551257) 1 NC_015844.1 Fructose-bisphosphate aldolase catalyzes the fourth step of the glycolysis (Embden-Meyerhof pathway). It cleaves the hexose D-fructose 1,6-bisphosphate into two trioses sugars: the dihydroxyacetone phosphate (ketone) and the D-glyceraldehyde 3-phosphate (aldehyde); Belongs to the DeoC/LacD aldolase family (Common phosphate binding- site TIM barrel superfamily); Localized in the cytoplasm; High confidence in function and specificity; fructose-bisphosphate aldolase, class 1 4551257 fbaB 10977914 fbaB Zobellia galactanivorans fructose-bisphosphate aldolase, class 1 YP_004738282.1 4550211 R 63186 CDS YP_004738283.1 340619830 10977818 complement(4551279..4552220) 1 NC_015844.1 6-Phosphofructokinase catalyzes the thirth step of glycolysis (Embden-Meyerhof pathway). It phosphoryles the D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. It is an allosteric homodimer enzyme. Because the reaction catalyzed by Phosphofructokinase is energetically very favorable, it is essentially irreversible; Belongs to the carbohydrate kinase PfkB family; Localized in the cytoplasm; High confidence in function and specificity; 6-phosphofructokinase, isozyme 2 4552220 pfkB 10977818 pfkB Zobellia galactanivorans 6-phosphofructokinase, isozyme 2 YP_004738283.1 4551279 R 63186 CDS YP_004738284.1 340619831 10978331 complement(4552252..4552941) 1 NC_015844.1 The 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (PGAM) catalyzes the step 8 of the glycolysis (Embden-Meyerhof pathway). PGAM catalyzes the internal transfer of a phosphate group from C-3 to C-2 which results in the conversion of 3-phosphoglycerate (3PG) to 2-phosphoglycerate (2PG) through a 2,3-bisphosphoglycerate intermediate; Belongs to the phosphoglycerate mutase family, BPG-dependent PGAM subfamily; Localized in the cytoplasm; High confidence in function and specificity; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 4552941 gpmA 10978331 gpmA Zobellia galactanivorans 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase YP_004738284.1 4552252 R 63186 CDS YP_004738285.1 340619832 10977947 complement(4552949..4553938) 1 NC_015844.1 NAD-dependent 2-hydroxyacid dehydrogenases are enzymes which seem to be specific for the D-isomer of their substrate. these enzymes are composed of a substrate-binding domain and a NAD-binding domain (Rossman fold); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity; 2-hydroxyacid dehydrogenase-like protein 4553938 ddh 10977947 ddh Zobellia galactanivorans 2-hydroxyacid dehydrogenase-like protein YP_004738285.1 4552949 R 63186 CDS YP_004738286.1 340619833 10977725 complement(4553986..4556394) 1 NC_015844.1 Phosphoenolpyruvate synthase is involved in gluconeogenesis when pyruvate and lactate are used as a carbon source. It generates phosphoenolpyruvate (PEP) from pyruvate, hydrolyzing ATP to AMP and releasing inorganic phosphate in the process; Uses the magnesium as cofactor; Belongs to the PEP-utilizing enzyme family; Localized in the cytoplasm; High confidence in function and specificity; phosphoenolpyruvate synthase 4556394 ppsA 10977725 ppsA Zobellia galactanivorans phosphoenolpyruvate synthase YP_004738286.1 4553986 R 63186 CDS YP_004738287.1 340619834 10978377 complement(4556397..4556501) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4556501 10978377 zobellia_3870 Zobellia galactanivorans hypothetical protein YP_004738287.1 4556397 R 63186 CDS YP_004738288.1 340619835 10976365 4556569..4558047 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). There are three copies each of the alpha and beta subunits that form the catalytic core of the F1 complex, while the remaining F1 subunits (gamma, delta, epsilon) form part of the stalks. There is a substrate-binding site on each of the alpha and beta subunits, those on the beta subunits being catalytic, while those on the alpha subunits are regulatory. The alpha and beta subunits form a cylinder that is attached to the central stalk. The alpha/beta subunits undergo a sequence of conformational changes leading to the formation of ATP from ADP, which are induced by the rotation of the gamma subunit, itself is driven by the movement of protons through the F0 complex C subunit.; High confidence in function and specificity; ATP synthase, F1 sector subunit beta 4558047 atpD2 10976365 atpD2 Zobellia galactanivorans ATP synthase, F1 sector subunit beta YP_004738288.1 4556569 D 63186 CDS YP_004738289.1 340619836 10977574 4558064..4558453 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). The interaction site of subunit C of the F0 complex with the epsilon subunit of the F1 complex may be important for connecting the rotor of F1 (gamma subunit) to the rotor of F0 (C subunit).; High confidence in function and specificity; ATP synthase, F1 sector subunit epsilon 4558453 atpC2 10977574 atpC2 Zobellia galactanivorans ATP synthase, F1 sector subunit epsilon YP_004738289.1 4558064 D 63186 CDS YP_004738290.1 340619837 10977572 4558450..4558782 1 NC_015844.1 This protein is highly; High confidence in function and specificity; ATP synthase gene 1 4558782 atpI 10977572 atpI Zobellia galactanivorans ATP synthase gene 1 YP_004738290.1 4558450 D 63186 CDS YP_004738291.1 340619838 10977582 4558868..4559077 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4559077 10977582 zobellia_3874 Zobellia galactanivorans membrane protein YP_004738291.1 4558868 D 63186 CDS YP_004738292.1 340619839 10976366 4559079..4559807 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). The A subunit is a key membrane component of the proton channel, and may play a direct role in the translocation of protons across the membrane. Catalysis in the F1 complex depends upon the rotation of the central stalk and F0 c-ring, which in turn is driven by the flux of protons through the membrane via the interface between the F0 c-ring and subunit A. The peripheral stalk links subunit A to the external surface of the F1 domain, and is thought to act as a stator to counter the tendency of subunit A and the F1 alpha-beta catalytic portion to rotate with the central rotary element.; High confidence in function and specificity; ATP synthase, F0 sector subunit A 4559807 atpB2 10976366 atpB2 Zobellia galactanivorans ATP synthase, F0 sector subunit A YP_004738292.1 4559079 D 63186 CDS YP_004738293.1 340619840 10977570 4559870..4560139 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). Ten C subunits form an oligomeric ring that makes up the F0 rotor. The flux of protons through the ATPase channel drives the rotation of the C subunit ring, which in turn is coupled to the rotation of the F1 complex gamma subunit rotor due to the permanent binding between the gamma and epsilon subunits of F1 and the C subunit ring of F0. The sequential protonation and deprotonation of Asp61 of subunit C is coupled to the stepwise movement of the rotor.; High confidence in function and specificity; ATP synthase, F0 sector subunit C 4560139 atpE2 10977570 atpE2 Zobellia galactanivorans ATP synthase, F0 sector subunit C YP_004738293.1 4559870 D 63186 CDS YP_004738294.1 340619841 10977576 4560147..4560893 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). The B subunits are part of the peripheral stalk that links the F1 and F0 complexes together, and which acts as a stator to prevent certain subunits from rotating with the central rotary element.; High confidence in function and specificity; ATP synthase, F0 sector subunit B 4560893 atpF2 10977576 atpF2 Zobellia galactanivorans ATP synthase, F0 sector subunit B YP_004738294.1 4560147 D 63186 CDS YP_004738295.1 340619842 10977578 4560916..4562445 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). There are three copies each of the alpha and beta subunits that form the catalytic core of the F1 complex, while the remaining F1 subunits (gamma, delta, epsilon) form part of the stalks. There is a substrate-binding site on each of the alpha and beta subunits, those on the beta subunits being catalytic, while those on the alpha subunits are regulatory. The alpha and beta subunits form a cylinder that is attached to the central stalk. The alpha/beta subunits undergo a sequence of conformational changes leading to the formation of ATP from ADP, which are induced by the rotation of the gamma subunit, itself is driven by the movement of protons through the F0 complex C subunit.; High confidence in function and specificity; ATP synthase, F1 sector subunit alpha 4562445 atpA2 10977578 atpA2 Zobellia galactanivorans ATP synthase, F1 sector subunit alpha YP_004738295.1 4560916 D 63186 CDS YP_004738296.1 340619843 10977568 4562464..4563369 1 NC_015844.1 ATP synthase produces ATP from ADP in the presence of a proton gradient across the membrane. F-type ATPases (also known as F1F0-ATPase, or H(+)-transporting two-sector ATPase) are composed of two linked complexes: the F1 ATPase complex is the catalytic core and is composed of 5 subunits (alpha, beta, gamma, delta, epsilon), while the F0 ATPase complex is the membrane-embedded proton channel that is composed of at least 3 subunits (A-C). In the F1 complex, the central gamma subunit forms the rotor inside the cylinder made of the alpha beta subunits, while in the F0 complex, the ring-shaped C subunits forms the rotor. The two rotors rotate in opposite directions, but the F0 rotor is usually stronger, using the force from the proton gradient to push the F1 rotor in reverse in order to drive ATP synthesis.; High confidence in function and specificity; ATP synthase, F1 sector subunit gamma 4563369 atpG2 10977568 atpG2 Zobellia galactanivorans ATP synthase, F1 sector subunit gamma YP_004738296.1 4562464 D 63186 CDS YP_004738297.1 340619844 10977580 complement(4563476..4563928) 1 NC_015844.1 Protein containing a Flavin mononucleotide binding domain; Belongs to the Pyridoxamine 5'-phosphate oxidase family; Localized in the cytoplasm; Function unclear; hypothetical protein 4563928 10977580 zobellia_3880 Zobellia galactanivorans hypothetical protein YP_004738297.1 4563476 R 63186 CDS YP_004738298.1 340619845 10976368 complement(4564208..4565188) 1 NC_015844.1 Periplasmic protein of unknown function anchored in the cytoplasmic membrane by a N-terminal transmembrane segment; could be involved in the uptake of organic solvents; Contains a Mce (mammalian cell entry) domain; Belongs to the periplasmic substrate-binding ABC transporter superfamily; Specificity unclear; ABC transporter periplasmic protein 4565188 10976368 zobellia_3881 Zobellia galactanivorans ABC transporter periplasmic protein YP_004738298.1 4564208 R 63186 CDS YP_004738299.1 340619846 10976369 complement(4565192..4565980) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasmic membrane as a peripheral membrane protein; Family membership; ABC transporter ATPase 4565980 10976369 zobellia_3882 Zobellia galactanivorans ABC transporter ATPase YP_004738299.1 4565192 R 63186 CDS YP_004738300.1 340619847 10976370 complement(4565977..4566753) 1 NC_015844.1 ABC (ATP-binding cassette) membrane protein responsible for translocation of a variety of compounds across biological membranes. Possibly involved in uptake of organic solvents such as gamma-Hexachlorocyclohexane or toluene for their utilization as source of carbon; Contains five transmembrane segments; Localized in the cytoplasmic membrane; Specificity unclear; ABC transporter permease 4566753 10976370 zobellia_3883 Zobellia galactanivorans ABC transporter permease YP_004738300.1 4565977 R 63186 CDS YP_004738301.1 340619848 10976371 complement(4566801..4566893) 1 NC_015844.1 Peptide that consists of a putative transmembrane helix possibly localized in the cytoplasmic membrane.; Hypothetical protein; hypothetical protein 4566893 10976371 zobellia_3884 Zobellia galactanivorans hypothetical protein YP_004738301.1 4566801 R 63186 CDS YP_004738302.1 340619849 10976372 4566946..4568277 1 NC_015844.1 Chloride channels constitute an evolutionarily well-conserved family of voltage-gated channels that are structurally unrelated to the other known voltage-gated channels. Features eleven transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; voltage-gated chloride channel 4568277 10976372 zobellia_3885 Zobellia galactanivorans voltage-gated chloride channel YP_004738302.1 4566946 D 63186 CDS YP_004738303.1 340619850 10976373 complement(4568344..4570716) 1 NC_015844.1 Glucan 1,4-alpha-glucosidase, also known as glucoamylase, catalyzes the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose. Belongs to the family 15 of the glycoside hydrolases. Involved in starch/glycogen metabolism.; High confidence in function and specificity; glucan 1,4-alpha-glucosidase 4570716 cgaA 10976373 cgaA Zobellia galactanivorans glucan 1,4-alpha-glucosidase YP_004738303.1 4568344 R 63186 CDS YP_004738304.1 340619851 10977644 complement(4570995..4571486) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4571486 10977644 zobellia_3887 Zobellia galactanivorans periplasmic protein YP_004738304.1 4570995 R 63186 CDS YP_004738305.1 340619852 10976374 complement(4571806..4572720) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4572720 10976374 zobellia_3888 Zobellia galactanivorans periplasmic protein YP_004738305.1 4571806 R 63186 CDS YP_004738306.1 340619853 10976375 4572830..4574956 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a Plug module (45-153) acting as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership; TonB-dependent Receptor 4574956 10976375 zobellia_3889 Zobellia galactanivorans TonB-dependent Receptor YP_004738306.1 4572830 D 63186 CDS YP_004738307.1 340619854 10976376 4574968..4576392 1 NC_015844.1 Signal peptide of prokaryotic lipoprotein cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4576392 10976376 zobellia_3890 Zobellia galactanivorans lipoprotein YP_004738307.1 4574968 D 63186 CDS YP_004738308.1 340619855 10976378 4576539..4576877 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 4576877 10976378 zobellia_3891 Zobellia galactanivorans hypothetical protein YP_004738308.1 4576539 D 63186 CDS YP_004738309.1 340619856 10976379 complement(4576941..4578824) 1 NC_015844.1 Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; hypothetical protein 4578824 10976379 zobellia_3892 Zobellia galactanivorans hypothetical protein YP_004738309.1 4576941 R 63186 CDS YP_004738310.1 340619857 10976380 4579211..4582294 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules (here possibly sugars) that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (26-98) and the Plug module (114-224) acting as a channel gate; The signal peptide is cleaved between the residues 24 and 25; Family membership; TonB-dependent Receptor 4582294 10976380 zobellia_3893 Zobellia galactanivorans TonB-dependent Receptor YP_004738310.1 4579211 D 63186 CDS YP_004738311.1 340619858 10976381 4582313..4583986 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 17 and 18; Probably localized in the cytoplasmic membrane; Family membership; SusD/RagB family lipoprotein 4583986 10976381 zobellia_3894 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004738311.1 4582313 D 63186 CDS YP_004738312.1 340619859 10976382 4584185..4585735 1 NC_015844.1 The Sugars permeases belong to the major facilitator superfamily (MFS) transporters that are single- polypeptide secondary carriers capable only of transporting small solutes (probably sugars in this case) in response to chemiosmotic ion gradients; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; sugar permease 4585735 10976382 zobellia_3895 Zobellia galactanivorans sugar permease YP_004738312.1 4584185 D 63186 CDS YP_004738313.1 340619860 10976383 4585732..4587327 1 NC_015844.1 Beta-xylosidase is an intracellular xylan-degrading enzyme. It catalyzes the hydrolysis of 1,4-beta-D-xylans, to remove successive D-xylose residues from the non-reducing termini. It belongs to the family GH43 of the glycoside hydrolases.; High confidence in function and specificity; beta-xylosidase 4587327 xynB 10976383 xynB Zobellia galactanivorans beta-xylosidase YP_004738313.1 4585732 D 63186 CDS YP_004738314.1 340619861 10978770 4587483..4588508 1 NC_015844.1 The LacI-type transcriptional regulators are involved in the repression and/or the positive regulation of genes encoding for catabolic enzymes and are important in the coordination of operons; They contain a N-terminal lacI-type HTH domain involved in the binding of the protein to the operator sequences in the DNA and a C- terminal periplasmic binding protein domain that are the primary receptors for chemotaxis and transport of many sugar based solutes that act as inducers; Localized in the cytoplasm; Family membership; LacI-type transcriptional regulator 4588508 10978770 zobellia_3897 Zobellia galactanivorans LacI-type transcriptional regulator YP_004738314.1 4587483 D 63186 CDS YP_004738315.1 340619862 10976384 4588876..4591371 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 4591371 10976384 zobellia_3898 Zobellia galactanivorans hypothetical protein YP_004738315.1 4588876 D 63186 CDS YP_004738316.1 340619863 10976385 4591425..4591562 1 NC_015844.1 Hypothetical protein; hypothetical protein 4591562 10976385 zobellia_3899 Zobellia galactanivorans hypothetical protein YP_004738316.1 4591425 D 63186 CDS YP_004738317.1 340619864 10976386 complement(4591584..4591979) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity which acts as transcriptional regulator. In this sequence, the effector domain is absent; Family membership; two-component system-response regulator, receiver domain 4591979 10976386 zobellia_3900 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004738317.1 4591584 R 63186 CDS YP_004738318.1 340619865 10976388 complement(4591991..4595971) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It autophosphorylates an histidine in its phosphoacceptor domain and phosphorylates an aspartic acid present in the response regulator receiver domain; Contains a CheB-type methylesterase catalytic domain and a CheR-type methyltransferase domain, both involved in the bacterial chemotaxis system; Contains a PAS/PAC domain; Seems localized in the cytoplasm; Family membership; two-component system hybrid-sensor histidine kinase/Chemotaxis proteins 4595971 10976388 zobellia_3901 Zobellia galactanivorans two-component system hybrid-sensor histidine kinase/Chemotaxis proteins YP_004738318.1 4591991 R 63186 CDS YP_004738319.1 340619866 10976389 complement(4596170..4596805) 1 NC_015844.1 Response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA- binding activity (here, a LuxR-type HTH domain) that acts as transcriptional regulator; Family membership; two-component system-response regulator 4596805 10976389 zobellia_3902 Zobellia galactanivorans two-component system-response regulator YP_004738319.1 4596170 R 63186 CDS YP_004738320.1 340619867 10976390 complement(4596795..4598798) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Signal peptide cleaved between the residues 20 and 21; Contains four N- terminal tetratrico peptide repeats (TPR); Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 4598798 10976390 zobellia_3903 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738320.1 4596795 R 63186 CDS YP_004738321.1 340619868 10976391 complement(4598815..4599006) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4599006 10976391 zobellia_3904 Zobellia galactanivorans hypothetical protein YP_004738321.1 4598815 R 63186 CDS YP_004738322.1 340619869 10976392 4599052..4599474 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 17 and 18; Possibly localized in the outer membrane; Hypothetical protein; hypothetical protein 4599474 10976392 zobellia_3905 Zobellia galactanivorans hypothetical protein YP_004738322.1 4599052 D 63186 CDS YP_004738323.1 340619870 10976393 4599481..4603404 1 NC_015844.1 This peptidase belongs to the family 4 of the metallopeptidases, which also contains thermolysin and related neutral peptidases. The conserved catalytic motif is HEXXE, in which the histidines are zinc ligands and the glutamate is a catalytic residue. The zinc ion is also bound by a second glutamate, 20-33 residues C-terminal to the HEXXH motif, and by an activated water molecule which forms the nucleophile in catalysis. Features a large C-terminal region of unknown function (621-1307), which includes a TSP3 calcium-binding domain. Features a signal peptide cleaved between the residues 22 and 23. Most members of the family M4 are secreted enzymes that degrade extracellular proteins and peptides for bacterial nutrition.; Specificity unclear; extracellular metallopeptidase 4603404 10976393 zobellia_3906 Zobellia galactanivorans extracellular metallopeptidase YP_004738323.1 4599481 D 63186 CDS YP_004738324.1 340619871 10976394 4603401..4604102 1 NC_015844.1 Protein that contains two type-III fibronectin (FN3) domains. Structures of individual FN3 domains have revealed a conserved beta sandwich fold found in glycoside hydrolases and other proteins; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the cytoplamic membrane; Family membership; fibronectin type-III repeat-containing protein 4604102 10976394 zobellia_3907 Zobellia galactanivorans fibronectin type-III repeat-containing protein YP_004738324.1 4603401 D 63186 CDS YP_004738325.1 340619872 10976395 4604103..4605395 1 NC_015844.1 This Protein likely adopts a beta-propeller fold; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4605395 10976395 zobellia_3908 Zobellia galactanivorans lipoprotein YP_004738325.1 4604103 D 63186 CDS YP_004738326.1 340619873 10976396 4605768..4607060 1 NC_015844.1 Protein that likely adopts a beta-propeller fold; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4607060 10976396 zobellia_3909 Zobellia galactanivorans lipoprotein YP_004738326.1 4605768 D 63186 CDS YP_004738327.1 340619874 10976397 4607267..4607848 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4607848 10976397 zobellia_3910 Zobellia galactanivorans membrane protein YP_004738327.1 4607267 D 63186 CDS YP_004738328.1 340619875 10976399 4608173..4608601 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 4608601 10976399 zobellia_3911 Zobellia galactanivorans hypothetical protein YP_004738328.1 4608173 D 63186 CDS YP_004738329.1 340619876 10976400 4608771..4609259 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Hypothetical protein; hypothetical protein 4609259 10976400 zobellia_3912 Zobellia galactanivorans hypothetical protein YP_004738329.1 4608771 D 63186 CDS YP_004738330.1 340619877 10976401 4609391..4609597 1 NC_015844.1 Hypothetical protein; hypothetical protein 4609597 10976401 zobellia_3913 Zobellia galactanivorans hypothetical protein YP_004738330.1 4609391 D 63186 CDS YP_004738331.1 340619878 10976402 4609719..4609817 1 NC_015844.1 Hypothetical protein; hypothetical protein 4609817 10976402 zobellia_3914 Zobellia galactanivorans hypothetical protein YP_004738331.1 4609719 D 63186 CDS YP_004738332.1 340619879 10976403 4609944..4610285 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4610285 10976403 zobellia_3915 Zobellia galactanivorans hypothetical protein YP_004738332.1 4609944 D 63186 CDS YP_004738333.1 340619880 10976404 4610248..4610751 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule. Belongs to GNAT actyltransferase family. Localized in the cytoplasm.; Family membership; GCN5-like N-acetyltransferase 4610751 10976404 zobellia_3916 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004738333.1 4610248 D 63186 CDS YP_004738334.1 340619881 10976405 4610816..4611367 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 4611367 10976405 zobellia_3917 Zobellia galactanivorans hypothetical protein YP_004738334.1 4610816 D 63186 CDS YP_004738335.1 340619882 10976406 complement(4611421..4611630) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4611630 10976406 zobellia_3918 Zobellia galactanivorans hypothetical protein YP_004738335.1 4611421 R 63186 CDS YP_004738336.1 340619883 10976407 4611702..4613675 1 NC_015844.1 The N-terminal region of this protein (~200 residues) is conserved. The C-terminal region (~400 residues) displays no similarity with known proteins; Localized in the cytoplasm; hypothetical protein 4613675 10976407 zobellia_3919 Zobellia galactanivorans hypothetical protein YP_004738336.1 4611702 D 63186 CDS YP_004738337.1 340619884 10976408 4613680..4614300 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Hypothetical protein; hypothetical protein 4614300 10976408 zobellia_3920 Zobellia galactanivorans hypothetical protein YP_004738337.1 4613680 D 63186 CDS YP_004738338.1 340619885 10976410 4614786..4615028 1 NC_015844.1 Protein almost always found adjacent to a plasmid stabilization protein, which is the killing partner of an addiction module for plasmid stabilization. This Protein, therefore, would be the putative addiction module antidote protein; Contains a conserved GRY motif; Belongs to the uncharacterised protein family UPF0156; Localized in the cytoplasm; Function unclear; addiction module antidote protein 4615028 10976410 zobellia_3921 Zobellia galactanivorans addiction module antidote protein YP_004738338.1 4614786 D 63186 CDS YP_004738339.1 340619886 10976411 4615025..4615327 1 NC_015844.1 Protein involved in plasmid stabilization. The exact molecular function of this protein is not known; Localized in the cytoplasm; Function unclear; Plasmid stabilisation system protein 4615327 10976411 zobellia_3922 Zobellia galactanivorans Plasmid stabilisation system protein YP_004738339.1 4615025 D 63186 CDS YP_004738340.1 340619887 10976412 complement(4615625..4615825) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4615825 10976412 zobellia_3923 Zobellia galactanivorans hypothetical protein YP_004738340.1 4615625 R 63186 CDS YP_004738341.1 340619888 10976413 4615943..4616548 1 NC_015844.1 Protein that contains three KWG repeats of unknown function; , Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4616548 10976413 zobellia_3924 Zobellia galactanivorans lipoprotein YP_004738341.1 4615943 D 63186 CDS YP_004738342.1 340619889 10976414 4616651..4617121 1 NC_015844.1 This protein belongs to a family of stress-induced proteins encompassing OsmC from Escherichia coli and OhrB from Bacillus subtilis. Localized in the cytoplasm.; Family membership; stress-induced protein 4617121 10976414 zobellia_3925 Zobellia galactanivorans stress-induced protein YP_004738342.1 4616651 D 63186 CDS YP_004738343.1 340619890 10976415 4617327..4617425 1 NC_015844.1 Hypothetical protein; hypothetical protein 4617425 10976415 zobellia_3926 Zobellia galactanivorans hypothetical protein YP_004738343.1 4617327 D 63186 CDS YP_004738344.1 340619891 10976416 4617453..4617566 1 NC_015844.1 Hypothetical protein; hypothetical protein 4617566 10976416 zobellia_3927 Zobellia galactanivorans hypothetical protein YP_004738344.1 4617453 D 63186 CDS YP_004738345.1 340619892 10976417 4617616..4618122 1 NC_015844.1 Contains one C-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4618122 10976417 zobellia_3928 Zobellia galactanivorans membrane protein YP_004738345.1 4617616 D 63186 CDS YP_004738346.1 340619893 10976418 4618186..4619019 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4619019 10976418 zobellia_3929 Zobellia galactanivorans hypothetical protein YP_004738346.1 4618186 D 63186 CDS YP_004738347.1 340619894 10976419 4619219..4619548 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4619548 10976419 zobellia_3930 Zobellia galactanivorans hypothetical protein YP_004738347.1 4619219 D 63186 CDS YP_004738348.1 340619895 10976421 4619567..4619920 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4619920 10976421 zobellia_3931 Zobellia galactanivorans hypothetical protein YP_004738348.1 4619567 D 63186 CDS YP_004738349.1 340619896 10976422 4620396..4620959 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 4620959 10976422 zobellia_3932 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004738349.1 4620396 D 63186 CDS YP_004738350.1 340619897 10976423 4621065..4622234 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 4622234 10976423 zobellia_3933 Zobellia galactanivorans anti-sigma factor YP_004738350.1 4621065 D 63186 CDS YP_004738351.1 340619898 10976424 4622460..4625882 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain (48-96)) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (121-195) and a Plug module (211-316) acting as the channel gate; The signal peptide is cleaved between the residue 19 and 20; Family membership; TonB-dependent transducer 4625882 10976424 zobellia_3934 Zobellia galactanivorans TonB-dependent transducer YP_004738351.1 4622460 D 63186 CDS YP_004738352.1 340619899 10976425 4625901..4627580 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 4627580 10976425 zobellia_3935 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004738352.1 4625901 D 63186 CDS YP_004738353.1 340619900 10976426 4627710..4630148 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 95 of the glycoside hydrolases (GH95); Features a lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the cytoplasmic membrane; High confidence in function and specificity; alpha-L-fucosidase 4630148 afcA7 10976426 afcA7 Zobellia galactanivorans alpha-L-fucosidase YP_004738353.1 4627710 D 63186 CDS YP_004738354.1 340619901 10977482 4630202..4632091 1 NC_015844.1 Conserved protein belonging to the DUF1680 family protein. Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Family membership; periplasmic protein 4632091 10977482 zobellia_3937 Zobellia galactanivorans periplasmic protein YP_004738354.1 4630202 D 63186 CDS YP_004738355.1 340619902 10976427 4632112..4634730 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; hypothetical protein 4634730 10976427 zobellia_3938 Zobellia galactanivorans hypothetical protein YP_004738355.1 4632112 D 63186 CDS YP_004738356.1 340619903 10976428 complement(4634892..4636430) 1 NC_015844.1 Serine endopeptidase belonging to the family S54. This family includes the protein Rhomboid which is a peptidase important for embryo development in Drosophila melanogaster. The active site is a catalytic diad Ser, His. Features ten transmembrane helices. Localized in the cytoplasmic membrane.; Specificity unclear; serine endopeptidase 4636430 10976428 zobellia_3939 Zobellia galactanivorans serine endopeptidase YP_004738356.1 4634892 R 63186 CDS YP_004738357.1 340619904 10976429 complement(4636721..4637563) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 4637563 10976429 zobellia_3940 Zobellia galactanivorans AraC family transcriptional regulator YP_004738357.1 4636721 R 63186 CDS YP_004738358.1 340619905 10976431 4637771..4638355 1 NC_015844.1 3-Hexulose-6-phosphate isomerase catalyzes the isomerization between 3-hexulose 6-phosphate and fructose 6-phosphate. Together with HxlA, may act as a formaldehyde detoxification system. It forms a homotetramer. Localized in the cytoplasm.; High confidence in function and specificity; 3-Hexulose-6-phosphate isomerase 4638355 hxlB 10976431 hxlB Zobellia galactanivorans 3-Hexulose-6-phosphate isomerase YP_004738358.1 4637771 D 63186 CDS YP_004738359.1 340619906 10978007 4638408..4639037 1 NC_015844.1 3-Hexulose-6-phosphate synthase catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate. Together with HxlB, may act as a formaldehyde detoxification system. Localized in the cytoplasm.; High confidence in function and specificity; 3-Hexulose-6-phosphate synthase 4639037 hxlA 10978007 hxlA Zobellia galactanivorans 3-Hexulose-6-phosphate synthase YP_004738359.1 4638408 D 63186 CDS YP_004738360.1 340619907 10978006 4639082..4639360 1 NC_015844.1 Hypothetical protein; hypothetical protein 4639360 10978006 zobellia_3943 Zobellia galactanivorans hypothetical protein YP_004738360.1 4639082 D 63186 CDS YP_004738361.1 340619908 10976432 4639393..4640349 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 4640349 10976432 zobellia_3944 Zobellia galactanivorans anti-sigma factor YP_004738361.1 4639393 D 63186 CDS YP_004738362.1 340619909 10976433 4640442..4643948 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules (here, Possibly sugars) that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (120-190), and a Plug module (210-315) acting as the channel gate; The signal peptide is cleaved between the residue 28 and 29; Family membership; TonB-dependent transducer 4643948 10976433 zobellia_3945 Zobellia galactanivorans TonB-dependent transducer YP_004738362.1 4640442 D 63186 CDS YP_004738363.1 340619910 10976434 4643961..4645694 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 16 and 17; Probably localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 4645694 10976434 zobellia_3946 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004738363.1 4643961 D 63186 CDS YP_004738364.1 340619911 10976435 4645705..4646571 1 NC_015844.1 The Endonuclease/exonuclease/phosphatase domain is found in a large number of proteins including magnesium dependent endonucleases and phosphatases involved in intracellular signalling; Belongs to the Endonuclease/Exonuclease/ phosphatase family; Signal peptide cleaved between the residues 22 and 23; Could be in the periplasmic space; Family membership; endonuclease/exonuclease/phosphatase family protein 4646571 10976435 zobellia_3947 Zobellia galactanivorans endonuclease/exonuclease/phosphatase family protein YP_004738364.1 4645705 D 63186 CDS YP_004738365.1 340619912 10976436 4646718..4647242 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 4647242 10976436 zobellia_3948 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004738365.1 4646718 D 63186 CDS YP_004738366.1 340619913 10976437 complement(4647373..4648158) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4648158 10976437 zobellia_3949 Zobellia galactanivorans periplasmic protein YP_004738366.1 4647373 R 63186 CDS YP_004738367.1 340619914 10976438 complement(4648192..4649496) 1 NC_015844.1 Conserved protein containing a N-terminal domain of unknown function and a C-terminal Xylose isomerase-like TIM barrel protein; Signal peptide cleaved between the residues 28 and 29; Localized in the periplasmic space; Family membership; xylose isomerase-like TIM barrel protein 4649496 10976438 zobellia_3950 Zobellia galactanivorans xylose isomerase-like TIM barrel protein YP_004738367.1 4648192 R 63186 CDS YP_004738368.1 340619915 10976440 4649779..4651209 1 NC_015844.1 Enzyme that Endohydrolyzes the beta-1,4-D-xylosidic linkages in xylans; Belongs to the family 10 of the glycoside hydrolases (GH10); This protein is a lipoprotein with a signal peptide cleaved between the residues 18 and 19 and probably localized in the outer membrane; Contains a PKD-like domain in its N-treminal region, probably involved in protein-carbohydrate interactions; High confidence in function and specificity; endo-beta-1,4-glucanase 4651209 xynA 10976440 xynA Zobellia galactanivorans endo-beta-1,4-glucanase YP_004738368.1 4649779 D 63186 CDS YP_004738369.1 340619916 10978769 4651240..4652436 1 NC_015844.1 Enzyme that Endohydrolyzes the beta-1,4-D-xylosidic linkages in xylans; Belongs to the family 10 of the glycoside hydrolases (GH10); This protein is a lipoprotein with a signal peptide cleaved between the residues 24 and 25, and probably localized in the outer membrane; High confidence in function and specificity; endo-beta-1,4-glucanase 4652436 xynB 10978769 xynB Zobellia galactanivorans endo-beta-1,4-glucanase YP_004738369.1 4651240 D 63186 CDS YP_004738370.1 340619917 10978771 4652476..4652877 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4652877 10978771 zobellia_3953 Zobellia galactanivorans periplasmic protein YP_004738370.1 4652476 D 63186 CDS YP_004738371.1 340619918 10976441 complement(4653022..4653918) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4653918 10976441 zobellia_3954 Zobellia galactanivorans periplasmic protein YP_004738371.1 4653022 R 63186 CDS YP_004738372.1 340619919 10976442 complement(4654216..4655415) 1 NC_015844.1 The tryptophan synthase catalyzes the fifth and the last step in the biosynthesis of tryptophan. It is a tetramer of two alpha and two beta chains. The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine; Uses the pyridoxal phosphate (vitamin B6) as cofactor; Localized in the cytoplasm; High confidence in function and specificity; tryptophan synthase subunit beta 4655415 trpB2 10976442 trpB2 Zobellia galactanivorans tryptophan synthase subunit beta YP_004738372.1 4654216 R 63186 CDS YP_004738373.1 340619920 10978694 4656161..4657594 1 NC_015844.1 Protein containing a N-terminal domain of unknown function and a C-terminal endonuclease domain. This endonuclease acts on both DNA and RNA, cleaves double-stranded and single-stranded nucleic acids and requires a divalent ion such as magnesium for its activity. A catalytic site is located in a conserved region which also contains an aspartate that could be implicated in the binding of the divalent ion; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; LOcalized in the outer membrane; Function unclear; DNA/RNA non-specific endonuclease 4657594 10978694 zobellia_3956 Zobellia galactanivorans DNA/RNA non-specific endonuclease YP_004738373.1 4656161 D 63186 CDS YP_004738374.1 340619921 10974051 4658292..4658675 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 4658675 10974051 zobellia_3958 Zobellia galactanivorans hypothetical protein YP_004738374.1 4658292 D 63186 CDS YP_004738375.1 340619922 10976444 4658733..4659578 1 NC_015844.1 D-Amino-acid transaminase acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate prosthetic group to form pyridoxamine and an alpha-keto acid in the first half-reaction. the second half-reaction transferes the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are essential bacterial cell wall components; Forms a homodimer and binds one pyridoxal phosphate as cofactor per subunit; Localized in the cytoplasm; High confidence in function and specificity; D-Amino-acid transaminase 4659578 datA 10976444 datA Zobellia galactanivorans D-Amino-acid transaminase YP_004738375.1 4658733 D 63186 CDS YP_004738376.1 340619923 10977721 complement(4659585..4660145) 1 NC_015844.1 Conserved protein belonging to the DUF179 family. Localized in the cytoplasm.; Family membership; hypothetical protein 4660145 10977721 zobellia_3960 Zobellia galactanivorans hypothetical protein YP_004738376.1 4659585 R 63186 CDS YP_004738377.1 340619924 10976446 complement(4660263..4660535) 1 NC_015844.1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. It forms a heterodimer of an alpha and a beta chain; Belongs to the bacterial histone-like protein family; localized in the cytoplasm.; High confidence in function and specificity; DNA-binding protein HU subunit beta 4660535 hupB 10976446 hupB Zobellia galactanivorans DNA-binding protein HU subunit beta YP_004738377.1 4660263 R 63186 CDS YP_004738378.1 340619925 10978004 complement(4660710..4661657) 1 NC_015844.1 Methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP. Its N-terminal domain carries the tetrahydrofolate (THF)-binding site and its C-terminal domain is presumably involved in positioning the Met-tRNA substrate for the formylation reaction. Localized in the cytoplasm.; High confidence in function and specificity; methionyl-tRNA formyltransferase 4661657 fmt 10978004 fmt Zobellia galactanivorans methionyl-tRNA formyltransferase YP_004738378.1 4660710 R 63186 CDS YP_004738379.1 340619926 10977834 complement(4661707..4663605) 1 NC_015844.1 The ATP-dependent DNA helicases are involved in unwinding of DNA; Contains a DEAD/H dopmain involved in the ATP binding and a Helicase conserved C-terminal domain; Belongs to superfamily II of helicases; Localized in the cytoplasm; High confidence in function and specificity; ATP-dependent DNA helicase 4663605 10977834 zobellia_3963 Zobellia galactanivorans ATP-dependent DNA helicase YP_004738379.1 4661707 R 63186 CDS YP_004738380.1 340619927 10976447 complement(4663605..4664168) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 4664168 10976447 zobellia_3964 Zobellia galactanivorans hypothetical protein YP_004738380.1 4663605 R 63186 CDS YP_004738381.1 340619928 10976448 4664256..4664543 1 NC_015844.1 YbeD adopts a alpha/beta fold with two alpha-helices on one side of a four-strand antiparallel beta-sheet. The beta-sheet surface contains a patch of conserved hydrophobic residues, suggesting a role in protein-protein interactions. YbeD shows striking structural homology to the regulatory domain from D-3- phosphoglycerate dehydrogenase, hinting at a role in the allosteric regulation of lipoic acid biosynthesis or the glycine cleavage system. Localized in the cytoplasm.; Conserved hypothetical protein; YbeD-like protein 4664543 10976448 zobellia_3965 Zobellia galactanivorans YbeD-like protein YP_004738381.1 4664256 D 63186 CDS YP_004738382.1 340619929 10976449 4664623..4665279 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 4665279 10976449 zobellia_3966 Zobellia galactanivorans hypothetical protein YP_004738382.1 4664623 D 63186 CDS YP_004738383.1 340619930 10976450 4665296..4666603 1 NC_015844.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase is involved in peptidoglycan biosynthesis. It adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin. It is localized in the cytoplasm.; High confidence in function and specificity; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 4666603 murA 10976450 murA Zobellia galactanivorans UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004738383.1 4665296 D 63186 CDS YP_004738384.1 340619931 10978199 4666619..4666939 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 4666939 10978199 zobellia_3968 Zobellia galactanivorans hypothetical protein YP_004738384.1 4666619 D 63186 CDS YP_004738385.1 340619932 10976451 complement(4666998..4667447) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Belongs to the Glyoxalase superfamily; Localized in the periplasmic space; Family membership; glyoxalase superfamily protein 4667447 10976451 zobellia_3969 Zobellia galactanivorans glyoxalase superfamily protein YP_004738385.1 4666998 R 63186 CDS YP_004738386.1 340619933 10976452 4667747..4668796 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4668796 10976452 zobellia_3970 Zobellia galactanivorans lipoprotein YP_004738386.1 4667747 D 63186 CDS YP_004738387.1 340619934 10976454 complement(4668817..4670127) 1 NC_015844.1 Deoxyribodipyrimidine photo-lyase is involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. It binds a reduced FAD moiety as prosthetic group, and, in addition, either a reduced pterin or 8-hydroxy-5-diazaflavin as a second chromophore; Localized in the cytoplasm.; High confidence in function and specificity; deoxyribodipyrimidine photo-lyase 4670127 phrA 10976454 phrA Zobellia galactanivorans deoxyribodipyrimidine photo-lyase YP_004738387.1 4668817 R 63186 CDS YP_004738388.1 340619935 10978351 complement(4670132..4670824) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 4670824 10978351 zobellia_3972 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004738388.1 4670132 R 63186 CDS YP_004738389.1 340619936 10976455 complement(4670838..4671476) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4671476 10976455 zobellia_3973 Zobellia galactanivorans hypothetical protein YP_004738389.1 4670838 R 63186 CDS YP_004738390.1 340619937 10976456 4671495..4672766 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4672766 10976456 zobellia_3974 Zobellia galactanivorans periplasmic protein YP_004738390.1 4671495 D 63186 CDS YP_004738391.1 340619938 10976457 4672847..4673692 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4673692 10976457 zobellia_3975 Zobellia galactanivorans periplasmic protein YP_004738391.1 4672847 D 63186 CDS YP_004738392.1 340619939 10976458 complement(4673796..4675538) 1 NC_015844.1 Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains thirteen transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sodium/solute symporter 4675538 10976458 zobellia_3976 Zobellia galactanivorans sodium/solute symporter YP_004738392.1 4673796 R 63186 CDS YP_004738393.1 340619940 10976459 complement(4675539..4675640) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4675640 10976459 zobellia_3977 Zobellia galactanivorans hypothetical protein YP_004738393.1 4675539 R 63186 CDS YP_004738394.1 340619941 10976460 complement(4675646..4678171) 1 NC_015844.1 Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides; Belongs to the family 14 of the carbohydrate esterases (CE14); Signal peptide cleaved between residues 20and 21; Localized in the periplasmic space; Specificity unclear; carbohydrate esterase 4678171 10976460 zobellia_3978 Zobellia galactanivorans carbohydrate esterase YP_004738394.1 4675646 R 63186 CDS YP_004738395.1 340619942 10976461 complement(4678320..4678865) 1 NC_015844.1 Mechanosensitive channels provide protection against hypo-osmotic shock, responding both to stretching of the cell membrane and to membrane depolarisation; Contains three transmembrane helices; Belongs to the small-conductance MS channels; Localized in the cytoplasmic membrane; Family membership; small-conductance mechanosensitive channel 4678865 10976461 zobellia_3979 Zobellia galactanivorans small-conductance mechanosensitive channel YP_004738395.1 4678320 R 63186 CDS YP_004738396.1 340619943 10976462 complement(4678874..4679821) 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 23 and 24; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 4679821 10976462 zobellia_3980 Zobellia galactanivorans membrane protein YP_004738396.1 4678874 R 63186 CDS YP_004738397.1 340619944 10976464 complement(4679858..4680439) 1 NC_015844.1 Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea; belongs to the Maf family; Localized in the cytoplasm.; Family membership; Maf-like protein 4680439 10976464 zobellia_3981 Zobellia galactanivorans Maf-like protein YP_004738397.1 4679858 R 63186 CDS YP_004738398.1 340619945 10976465 complement(4680442..4680969) 1 NC_015844.1 KdsC is involved in lipolysaccharides (LPS) biosynthesis. It catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate; Binds one magnesium as cofactor; Localized in the cytoplasm; High confidence in function and specificity; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 4680969 kdsC 10976465 kdsC Zobellia galactanivorans 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_004738398.1 4680442 R 63186 CDS YP_004738399.1 340619946 10978057 complement(4680953..4681717) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 4681717 10978057 zobellia_3983 Zobellia galactanivorans hypothetical protein YP_004738399.1 4680953 R 63186 CDS YP_004738400.1 340619947 10976466 4682015..4685218 1 NC_015844.1 NrfI may play a role in cytochrome c biogenesis and may be required for maturation of the NrfA protein, involved in nitrite reduction; Contains 12 transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; protein NrfI 4685218 nrfI 10976466 nrfI Zobellia galactanivorans protein NrfI YP_004738400.1 4682015 D 63186 CDS YP_004738401.1 340619948 10978271 complement(4685230..4685814) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 4685814 10978271 zobellia_3985 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004738401.1 4685230 R 63186 CDS YP_004738402.1 340619949 10976467 4685934..4687085 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 4687085 10976467 zobellia_3986 Zobellia galactanivorans anti-sigma factor YP_004738402.1 4685934 D 63186 CDS YP_004738403.1 340619950 10976468 4687248..4690628 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain (50-101)) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (134-198) and a Plug module (214-320) acting as the channel gate; The signal peptide is cleaved between the residue 19 and 20; Family membership; TonB-dependent transducer 4690628 10976468 zobellia_3987 Zobellia galactanivorans TonB-dependent transducer YP_004738403.1 4687248 D 63186 CDS YP_004738404.1 340619951 10976469 4690633..4692414 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 22 and 23; Probably localized in the cytoplasmic membrane; Family membership; SusD/RagB family lipoprotein 4692414 10976469 zobellia_3988 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004738404.1 4690633 D 63186 CDS YP_004738405.1 340619952 10976470 4692734..4693297 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to specific initiation sites (promoters) and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra-cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 4693297 10976470 zobellia_3989 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004738405.1 4692734 D 63186 CDS YP_004738406.1 340619953 10976471 4693489..4694616 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 4694616 10976471 zobellia_3990 Zobellia galactanivorans anti-sigma factor YP_004738406.1 4693489 D 63186 CDS YP_004738407.1 340619954 10976473 complement(4694636..4694746) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4694746 10976473 zobellia_3992 Zobellia galactanivorans hypothetical protein YP_004738407.1 4694636 R 63186 CDS YP_004738408.1 340619955 10976475 4694751..4698161 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension (Secretin/TonB (STN) domain (58-108)) that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (128-202), and a Plug module (218-325) acting as the channel gate; The signal peptide is cleaved between the residue 27 and 28; Family membership; TonB-dependent transducer 4698161 10976475 zobellia_3991 Zobellia galactanivorans TonB-dependent transducer YP_004738408.1 4694751 D 63186 CDS YP_004738409.1 340619956 10976474 4698165..4699835 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 30 and 31; Putatively localized in the cytoplasmic membrane; Family membership; SusD/RagB family lipoprotein 4699835 10976474 zobellia_3993 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004738409.1 4698165 D 63186 CDS YP_004738410.1 340619957 10976476 4699838..4702366 1 NC_015844.1 Contains a signal peptide cleaved between the residues 28 and 29; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4702366 10976476 zobellia_3994 Zobellia galactanivorans periplasmic protein YP_004738410.1 4699838 D 63186 CDS YP_004738411.1 340619958 10976477 4702419..4703981 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 15; Putative lipoprotein with a signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; Family membership; sulfatase 4703981 10976477 zobellia_3995 Zobellia galactanivorans sulfatase YP_004738411.1 4702419 D 63186 CDS YP_004738412.1 340619959 10976478 4704350..4705030 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Contains a C-terminal transmembrane segment; Belongs to family 11 of transposases; Localized in the cytoplasmic membrane; Family membership; transposase, family 11 4705030 10976478 zobellia_3996 Zobellia galactanivorans transposase, family 11 YP_004738412.1 4704350 D 63186 CDS YP_004738413.1 340619960 10976479 complement(4705119..4706738) 1 NC_015844.1 Conserved protein containing a putative FAD-binding domain in the N-terminal region. Features a N-terminal transmembrane helix. Localized in the cytoplasmic membrane.; Conserved hypothetical protein; FAD-binding protein 4706738 10976479 zobellia_3997 Zobellia galactanivorans FAD-binding protein YP_004738413.1 4705119 R 63186 CDS YP_004738414.1 340619961 10976480 complement(4706716..4707318) 1 NC_015844.1 Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of mRNA. Belongs to the ribonuclease L-PSP family. This family includes the rat liver perchloric acid-soluble protein (L-PSP), which has been shown to be a ribonuclease, and the protein yabJ from Bacillus subtilis involved in the regulation of the purine biosynthetic gene purA. Localized in the cytoplasm.; Family membership; endoribonuclease 4707318 10976480 zobellia_3998 Zobellia galactanivorans endoribonuclease YP_004738414.1 4706716 R 63186 CDS YP_004738415.1 340619962 10976481 4707918..4708667 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to family 11 of transposases; Contains two transmembrane helices, the first in N-terminus, the second in C-terminus; Localized in the cytoplasmic membrane; Family membership; transposase, family 11 4708667 10976481 zobellia_3999 Zobellia galactanivorans transposase, family 11 YP_004738415.1 4707918 D 63186 CDS YP_004738416.1 340619963 10976482 4708925..4710334 1 NC_015844.1 Multidrug efflux pump that functions probably as a Na(+)/drug antiporter; Contains 12 transmembrane segments; Belongs to the multi antimicrobial extrusion (MATE) family, MdtK subfamily; Localize in the cytoplasmic membrane; Specificity unclear; multidrug resistance protein 4710334 norM2 10976482 norM2 Zobellia galactanivorans multidrug resistance protein YP_004738416.1 4708925 D 63186 CDS YP_004738417.1 340619964 10978258 4710375..4711550 1 NC_015844.1 Cystathionine beta-lyase (CBL) is found in the Selenoamino acids metabolism pathway and in methionine and cysteine biosynthesis pathways. It converts (seleno)cystathionine to (seleno)homocysteine but is also able to catalyze an alpha, gamma elimination; Uses a pyridoxal phosphate group as cofactor, attached to a lysine residue located in the central section of the enzyme; Localized in the cytoplasm; High confidence in function and specificity; cystathionine beta-lyase 4711550 metC 10978258 metC Zobellia galactanivorans cystathionine beta-lyase YP_004738417.1 4710375 D 63186 CDS YP_004738418.1 340619965 10978148 4711592..4712314 1 NC_015844.1 Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides; Belongs to the family 14 of the carbohydrate esterases (CE14); Localized in the cytoplasm; Specificity unclear; carbohydrate esterase 4712314 10978148 zobellia_4002 Zobellia galactanivorans carbohydrate esterase YP_004738418.1 4711592 D 63186 CDS YP_004738419.1 340619966 10976485 complement(4712311..4714401) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains five N-terminal tetratrico peptide repeats (TPR) and two transmembrane segments; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 4714401 10976485 zobellia_4003 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738419.1 4712311 R 63186 CDS YP_004738420.1 340619967 10974052 complement(4714827..4715813) 1 NC_015844.1 The transposases are encoded by mobile genetic elements such as transposon or insertion sequences (IS). Transposases catalyze the transposition, by site-specific DNA recombination, of these autonomous mobile genetic elements. The catalytic activity of this enzyme family involves DNA cleavage followed by a strand transfer reaction; Belongs to the family 12 of transposases family; Localized in the cytoplasm; Family membership; transposase, family 12 4715813 10974052 zobellia_4005 Zobellia galactanivorans transposase, family 12 YP_004738420.1 4714827 R 63186 CDS YP_004738421.1 340619968 10976487 complement(4715800..4716153) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4716153 10976487 zobellia_4006 Zobellia galactanivorans hypothetical protein YP_004738421.1 4715800 R 63186 CDS YP_004738422.1 340619969 10976488 complement(4716270..4717838) 1 NC_015844.1 Family M28 contains aminopeptidases and carboxypeptidases with two co-catalytic zinc ions. Each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the outer membrane; Specificity unclear; metallopeptidase 4717838 10976488 zobellia_4007 Zobellia galactanivorans metallopeptidase YP_004738422.1 4716270 R 63186 CDS YP_004738423.1 340619970 10976489 4717990..4719177 1 NC_015844.1 Aldose 1-epimerase or Mutarotase is responsible for the anomeric interconversion of aldoses between their alpha- and beta-forms; It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; localized in the outer membrane; High confidence in function and specificity; aldose 1-epimerase 4719177 mroA4 10976489 mroA4 Zobellia galactanivorans aldose 1-epimerase YP_004738423.1 4717990 D 63186 CDS YP_004738424.1 340619971 10978186 complement(4719174..4720046) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons. Contains a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization and two C-terminal AraC- type HTH DNA-binding domains involved in the binding of the protein to the operator sequences in the DNA. Localized in the cytoplasm.; Family membership; AraC family transcriptional regulator 4720046 10978186 zobellia_4009 Zobellia galactanivorans AraC family transcriptional regulator YP_004738424.1 4719174 R 63186 CDS YP_004738425.1 340619972 10976490 4720189..4721127 1 NC_015844.1 Dihydropicolinate synthase (DHDPS) is the key enzyme in lysine biosynthesis via the diaminopimelate pathway of prokaryotes, some phycomycetes and higher plants. The enzyme catalyses the condensation of L- aspartate-beta-semialdehyde and pyruvate to dihydropicolinic acid via a ping-pong mechanism in which pyruvate binds to the enzyme by forming a Schiff-base with a lysine residue; localized in the cytoplasm; High confidence in function and specificity; dihydrodipicolinate synthetase 4721127 dapA1 10976490 dapA1 Zobellia galactanivorans dihydrodipicolinate synthetase YP_004738425.1 4720189 D 63186 CDS YP_004738426.1 340619973 10977714 4721294..4722880 1 NC_015844.1 Catalyzes the oxidation of long-chain aliphatic aldehydes to acids., Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor; located in the cytoplasm; High confidence in function and specificity; NADP-dependent fatty aldehyde dehydrogenase 4722880 aldH 10977714 aldH Zobellia galactanivorans NADP-dependent fatty aldehyde dehydrogenase YP_004738426.1 4721294 D 63186 CDS YP_004738427.1 340619974 10977494 4722911..4723918 1 NC_015844.1 Proline racemase catalyzes the interconversion of L-and D-proline. It forms a homodimer. Localized in the cytoplasm.; High confidence in function and specificity; proline racemase 4723918 10977494 zobellia_4012 Zobellia galactanivorans proline racemase YP_004738427.1 4722911 D 63186 CDS YP_004738428.1 340619975 10976492 4723932..4725182 1 NC_015844.1 D-amino acid dehydrogenase is involved in D-amino acids degradation. It converts a D-amino acid to a 2-oxo acid and ammoniac; Binds a FAD as cofactor; Localized in the cytoplasm; High confidence in function and specificity; D-amino acid dehydrogenase 4725182 dadA 10976492 dadA Zobellia galactanivorans D-amino acid dehydrogenase YP_004738428.1 4723932 D 63186 CDS YP_004738429.1 340619976 10977713 4725295..4726674 1 NC_015844.1 Cytochrome d terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at low aeration. It catalyzes the reaction: Ubiquinol-8 + O2 = Ubiquinone-8 + H2O. It is a heterodimer of subunits I and II. Binds 3 heme groups per dimer. Contains the protoheme IX center b595 and one iron-chlorin (heme D). Features nine transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; cytochrome d ubiquinol oxidase subunit I 4726674 cydA 10977713 cydA Zobellia galactanivorans cytochrome d ubiquinol oxidase subunit I YP_004738429.1 4725295 D 63186 CDS YP_004738430.1 340619977 10977695 4726681..4727718 1 NC_015844.1 Cytochrome d terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at low aeration. It catalyzes the reaction: Ubiquinol-8 + O2 = Ubiquinone-8 + H2O. It is a heterodimer of subunits I and II. Binds 3 heme groups per dimer. Contains the protoheme IX center b595 and one iron-chlorin (heme D). Features nine transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; cytochrome d ubiquinol oxidase subunit II 4727718 cydB 10977695 cydB Zobellia galactanivorans cytochrome d ubiquinol oxidase subunit II YP_004738430.1 4726681 D 63186 CDS YP_004738431.1 340619978 10977696 complement(4727726..4728115) 1 NC_015844.1 Conserved protein belonging to the Glyoxalase superfamily, which includes Glyoxalase I (lactoylglutathione lyase), but also Bleomycin resistance protein and various dioxygenases. Localized in the cytoplasm.; Family membership; glyoxalase superfamily protein 4728115 10977696 zobellia_4016 Zobellia galactanivorans glyoxalase superfamily protein YP_004738431.1 4727726 R 63186 CDS YP_004738432.1 340619979 10976493 complement(4728112..4728690) 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 4728690 10976493 zobellia_4017 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004738432.1 4728112 R 63186 CDS YP_004738433.1 340619980 10976494 complement(4728687..4729334) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4729334 10976494 zobellia_4018 Zobellia galactanivorans hypothetical protein YP_004738433.1 4728687 R 63186 CDS YP_004738434.1 340619981 10976495 4729390..4729833 1 NC_015844.1 Conserved esterase belonging to the thioesterase superfamily. Its specificity is unknown. Localized in the cytoplasm.; Specificity unclear; esterase 4729833 10976495 zobellia_4019 Zobellia galactanivorans esterase YP_004738434.1 4729390 D 63186 CDS YP_004738435.1 340619982 10976496 4729833..4730948 1 NC_015844.1 The isochorismate synthase, called also isochorismate mutase catalyses the conversion of chorismate to isochorismate, the first step in the biosynthesis of both respiratory chain components: menaquinone (MK, vitamin K2) and phylloquinone (vitamin K1); Localized in the cytoplasm; High confidence in function and specificity; menaquinone-specific isochorismate synthase 4730948 menF 10976496 menF Zobellia galactanivorans menaquinone-specific isochorismate synthase YP_004738435.1 4729833 D 63186 CDS YP_004738436.1 340619983 10978145 4730989..4732767 1 NC_015844.1 The 2-oxoglutarate decarboxylase/SHCHC synthase is a thiamine pyrophosphate bifunctional enzyme involved in the second step of the menaquinone biosynthesis pathway from chorismate. It displays a 2-oxoglutarate decarboxylase activity (alpha-ketoglutarate decarboxylase; KDC) and a 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate synthase (SHCHC) activity; Uses the thiamine pyrophosphate (vitamin B1) and the magnesium ion as cofactors; Belongs to the Thiamine Pyrophosphte enzyme family; Localized in the cytoplasm; High confidence in function and specificity; 2-oxoglutarate decarboxylase/SHCHC synthase 4732767 menD 10978145 menD Zobellia galactanivorans 2-oxoglutarate decarboxylase/SHCHC synthase YP_004738436.1 4730989 D 63186 CDS YP_004738437.1 340619984 10978143 4732797..4733135 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4733135 10978143 zobellia_4022 Zobellia galactanivorans hypothetical protein YP_004738437.1 4732797 D 63186 CDS YP_004738438.1 340619985 10976498 4733218..4734048 1 NC_015844.1 Seems to contains a C-terminal OB motif involved in the oligonucleotide/oligosaccharide binding; Localized in the cytoplasm; hypothetical protein 4734048 10976498 zobellia_4023 Zobellia galactanivorans hypothetical protein YP_004738438.1 4733218 D 63186 CDS YP_004738439.1 340619986 10976499 4734235..4734834 1 NC_015844.1 Protein with a simple bitopic topology: a short N-terminal cytoplasmic segment fused to a large carboxy periplasmic domain through a single transmembrane domain that could be involved in the cell division; Contains a central transmembrane segments; Localized in the cytoplasmic membrane; hypothetical protein 4734834 10976499 zobellia_4024 Zobellia galactanivorans hypothetical protein YP_004738439.1 4734235 D 63186 CDS YP_004738440.1 340619987 10976500 4734837..4735745 1 NC_015844.1 Converts the 1,4-dihydroxy-2-naphthoate (DHNA) to dimethylmenaquinone (DMK), the seventh step in the menaquinone (vitamin K2) biosynthesis pathway from chorismate; The conversion of DHNA to DMK proceeds in three stages: the removal of the carboxyl group of DHNA as CO(2), the attachment of the isoprenoid side chain, and a quinol-to-quinone oxidation, which is thought to be spontaneous. Attaches octaprenylpyrophosphate, a membrane-bound 40-carbon side chain to DHNA; Contains eight transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 4735745 menA 10976500 menA Zobellia galactanivorans 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_004738440.1 4734837 D 63186 CDS YP_004738441.1 340619988 10978140 4735780..4736532 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, which acts as transcriptional regulator; Localized in the cytoplasm; Family membership; two-component system-response regulator 4736532 10978140 zobellia_4026 Zobellia galactanivorans two-component system-response regulator YP_004738441.1 4735780 D 63186 CDS YP_004738442.1 340619989 10976501 4737110..4739107 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two transmembrane segments and three N-terminal tetratrico peptide repeats (TPR); Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 4739107 10976501 zobellia_4027 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738442.1 4737110 D 63186 CDS YP_004738443.1 340619990 10976502 complement(4739094..4739270) 1 NC_015844.1 Possible fragment of 3-oxoacyl-[acyl-carrier protein] reductase; Putatively localized in the cytoplasm; hypothetical protein 4739270 10976502 zobellia_4028 Zobellia galactanivorans hypothetical protein YP_004738443.1 4739094 R 63186 CDS YP_004738444.1 340619991 10976503 4739402..4740454 1 NC_015844.1 Enzyme involved in the third step of the menaquinone biosynthesis pathway from the chorismate. It converts the 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to O-succinylbenzoate (OSB); Uses the magnesium ion as cofactor; Belongs to the mandelate racemase/muconate lactonizing enzyme family; Localized in the cytoplasm; High confidence in function and specificity; O-succinylbenzoate synthase 4740454 menC 10976503 menC Zobellia galactanivorans O-succinylbenzoate synthase YP_004738444.1 4739402 D 63186 CDS YP_004738445.1 340619992 10978142 4740445..4741428 1 NC_015844.1 Conserved peptidase belonging to the family U48, which includes prenyl peptidases. Its exact specificity is unknown. Features eight transmembrane helices. Localized in the cytoplasmic membrane.; Function unclear; peptidase, family U48 4741428 10978142 zobellia_4030 Zobellia galactanivorans peptidase, family U48 YP_004738445.1 4740445 D 63186 CDS YP_004738446.1 340619993 10976505 4741394..4742485 1 NC_015844.1 the O-succinylbenzoic acid-CoA ligase converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA) in the fourth step of the menaquinone (vitamin K2) biosynthesis pathway from chorismate; Contains an AMP-binding domain; Belongs to the ATP-dependent AMP-binding enzyme family; Localized in the cytoplasm; High confidence in function and specificity; O-succinylbenzoic acid-CoA ligase 4742485 menE 10976505 menE Zobellia galactanivorans O-succinylbenzoic acid-CoA ligase YP_004738446.1 4741394 D 63186 CDS YP_004738447.1 340619994 10978144 complement(4742508..4744136) 1 NC_015844.1 Methylcrotonoyl-CoA carboxylase is involved in leucine catabolism. It catalyzes the reaction: ATP + 3-methylcrotonoyl-CoA + HCO3- = ADP + phosphate + 3-methylglutaconyl-CoA. It forms a dodecamer composed of six biotin-containing alpha subunits and six beta subunits. Localized in the cytoplasm.; High confidence in function and specificity; methylcrotonoyl-CoA carboxylase subunit beta 4744136 mccB 10978144 mccB Zobellia galactanivorans methylcrotonoyl-CoA carboxylase subunit beta YP_004738447.1 4742508 R 63186 CDS YP_004738448.1 340619995 10978128 4744210..4745208 1 NC_015844.1 NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family; Adopts a Rossmann fold; Localized in the cytoplasm; Specificity unclear; NAD(P)-dependent oxidoreductase 4745208 10978128 zobellia_4033 Zobellia galactanivorans NAD(P)-dependent oxidoreductase YP_004738448.1 4744210 D 63186 CDS YP_004738449.1 340619996 10976506 4745268..4745450 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4745450 10976506 zobellia_4034 Zobellia galactanivorans membrane protein YP_004738449.1 4745268 D 63186 CDS YP_004738450.1 340619997 10976507 4745493..4747184 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Contains a duplicated ATPase domain; Belongs to the ABC transporter family, EF3 subfamily; Localized in the cytoplasm near of the cytoplasmic membrane by association with a membrane permease component; Family membership; ABC transporter ATPase 4747184 10976507 zobellia_4035 Zobellia galactanivorans ABC transporter ATPase YP_004738450.1 4745493 D 63186 CDS YP_004738451.1 340619998 10976508 complement(4747257..4748075) 1 NC_015844.1 Protein belonging to the zinc-dependent beta-lactamase superfamily. This superfamily contains various metallo-hydrolases including beta-lactamases, but also glyoxylases and arylsulfatases. The active site is characterized by several conserved histidines binding one or two catalytic zinc ions; Contains a putative lipoprotein signal peptide cleaved between the residues 17 and 18; Possibly localized in the outer membrane; Family membership; metallo-beta-lactamase superfamily protein 4748075 10976508 zobellia_4036 Zobellia galactanivorans metallo-beta-lactamase superfamily protein YP_004738451.1 4747257 R 63186 CDS YP_004738452.1 340619999 10976509 complement(4748088..4748543) 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 4748543 10976509 zobellia_4037 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004738452.1 4748088 R 63186 CDS YP_004738453.1 340620000 10976510 4748712..4749599 1 NC_015844.1 Contains an uncleaved signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4749599 10976510 zobellia_4038 Zobellia galactanivorans membrane protein YP_004738453.1 4748712 D 63186 CDS YP_004738454.1 340620001 10976511 complement(4749680..4751113) 1 NC_015844.1 The fumarate hydratase FumC is involved in the tricarboxylic acid cycle. It catalyzes the reaction: (S)-malate = fumarate + H2O. FumC forms a homotetramer. There are 2 substrate binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. FumC belongs to the class II of the fumarase/aspartase family. Localized in the cytoplasm.; High confidence in function and specificity; fumarate hydratase, class II 4751113 fumC 10976511 fumC Zobellia galactanivorans fumarate hydratase, class II YP_004738454.1 4749680 R 63186 CDS YP_004738455.1 340620002 10977869 4751239..4751409 1 NC_015844.1 Putatively localized in the cytoplasm.; hypothetical protein 4751409 10977869 zobellia_4040 Zobellia galactanivorans hypothetical protein YP_004738455.1 4751239 D 63186 CDS YP_004738456.1 340620003 10976513 complement(4751539..4754037) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (32-116) and the Plug module (132-229) acting as a channel gate; The signal peptide is cleaved between the residues 18 and 19; Family membership; TonB-dependent Receptor 4754037 10976513 zobellia_4041 Zobellia galactanivorans TonB-dependent Receptor YP_004738456.1 4751539 R 63186 CDS YP_004738457.1 340620004 10976514 complement(4754039..4754542) 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4754542 10976514 zobellia_4042 Zobellia galactanivorans membrane protein YP_004738457.1 4754039 R 63186 CDS YP_004738458.1 340620005 10976515 complement(4754735..4755076) 1 NC_015844.1 ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. Glutaredoxin functions as the electron donor for arsenate reduction. ArsC also uses molybdenum as a cofactor. ArsC expands the substrate specificity of arsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance. Localized in the cytoplasm.; High confidence in function and specificity; Arsenate reductase 4755076 arsC 10976515 arsC Zobellia galactanivorans Arsenate reductase YP_004738458.1 4754735 R 63186 CDS YP_004738459.1 340620006 10977552 complement(4755112..4756098) 1 NC_015844.1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. It possess a peptidyl-tRNA hydrolase activity. Localized in the cytoplasm.; High confidence in function and specificity; peptide chain release factor 2 4756098 prfB 10977552 prfB Zobellia galactanivorans peptide chain release factor 2 YP_004738459.1 4755112 R 63186 CDS YP_004738460.1 340620007 10978379 complement(4756351..4757208) 1 NC_015844.1 Protein belonging to the transglutaminase-like superfamily. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterised transglutaminase; Localized in the cytoplasm; Family membership; transglutaminase-like protein 4757208 10978379 zobellia_4045 Zobellia galactanivorans transglutaminase-like protein YP_004738460.1 4756351 R 63186 CDS YP_004738461.1 340620008 10976516 complement(4757280..4758227) 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF403 family; Localized in the cytoplasm; hypothetical protein 4758227 10976516 zobellia_4046 Zobellia galactanivorans hypothetical protein YP_004738461.1 4757280 R 63186 CDS YP_004738462.1 340620009 10976517 complement(4758302..4759765) 1 NC_015844.1 Conserved hypothetical protein with two domains of unknown function belonging to the families DUF404 and DUF407, respectively; Localized in the cytoplasm; hypothetical protein 4759765 10976517 zobellia_4047 Zobellia galactanivorans hypothetical protein YP_004738462.1 4758302 R 63186 CDS YP_004738463.1 340620010 10976518 4760011..4761033 1 NC_015844.1 The L-allo-threonine aldolase is an enzyme involved in the Glycine metabolism. It converts the L-allo-Threonine and the threonine to glycine; Uses a pyridoxal phosphate group as cofactor; Localized in the cytoplasm; High confidence in function and specificity; L-allo-threonine aldolase 4761033 ltaA 10976518 ltaA Zobellia galactanivorans L-allo-threonine aldolase YP_004738463.1 4760011 D 63186 CDS YP_004738464.1 340620011 10978109 complement(4761035..4761367) 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF1508 family; Localized in the cytoplasm; hypothetical protein 4761367 10978109 zobellia_4049 Zobellia galactanivorans hypothetical protein YP_004738464.1 4761035 R 63186 CDS YP_004738465.1 340620012 10976519 4761562..4762662 1 NC_015844.1 This conserved protein belongs to the OmpA-like family. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space and/or in the outer membrane; Family membership; OmpA-like periplasmic protein 4762662 10976519 zobellia_4050 Zobellia galactanivorans OmpA-like periplasmic protein YP_004738465.1 4761562 D 63186 CDS YP_004738466.1 340620013 10976520 complement(4762712..4763158) 1 NC_015844.1 Conserved protein belonging to the thioredoxin family. Thioredoxins are small proteins of approximately one hundred amino-acid residues which participate in various redox reactions via the reversible oxidation of an active center disulfide bond; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Family membership; thioredoxin family protein 4763158 10976520 zobellia_4051 Zobellia galactanivorans thioredoxin family protein YP_004738466.1 4762712 R 63186 CDS YP_004738467.1 340620014 10976521 complement(4763200..4763526) 1 NC_015844.1 Protein of unknown function belonging to the YbaB family (DUF 149); Localized in the cytoplasm; Family membership; hypothetical protein 4763526 10976521 zobellia_4052 Zobellia galactanivorans hypothetical protein YP_004738467.1 4763200 R 63186 CDS YP_004738468.1 340620015 10976522 4763592..4765733 1 NC_015844.1 Oligopeptidase B Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues. The active site residues are in the order Ser, Asp, His in the sequence; Belongs to the family 9 of the serine peptidases (S9); Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; High confidence in function and specificity; oligopeptidase B 4765733 ptrB 10976522 ptrB Zobellia galactanivorans oligopeptidase B YP_004738468.1 4763592 D 63186 CDS YP_004738469.1 340620016 10978398 4765996..4767039 1 NC_015844.1 The cysteine synthase is the enzyme responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulfide with the concomitant release of acetic acid; Uses the pyridoxal phosphate as cofactor (vitamin B6) attached to a conserved lysine residue; Belongs to the cysteine synthase/cystathionine beta-synthase family; Localized in the cytoplasm; High confidence in function and specificity; cysteine synthase A 4767039 cysK1 10978398 cysK1 Zobellia galactanivorans cysteine synthase A YP_004738469.1 4765996 D 63186 CDS YP_004738470.1 340620017 10977705 4767164..4768423 1 NC_015844.1 Enzyme involved in the Glycine, serine and threonine metabolism, and in particular, in the glycine catabolism; Also called 2-amino-3-ketobutyrate coenzyme A ligase; Uses the Pyridoxal phosphate as cofactor; Belongs to the class II of the pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity; glycine C-acetyltransferase 4768423 kblA3 10977705 kblA3 Zobellia galactanivorans glycine C-acetyltransferase YP_004738470.1 4767164 D 63186 CDS YP_004738471.1 340620018 10978051 complement(4768523..4769641) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4769641 10978051 zobellia_4056 Zobellia galactanivorans hypothetical protein YP_004738471.1 4768523 R 63186 CDS YP_004738472.1 340620019 10976523 complement(4769735..4770820) 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4770820 10976523 zobellia_4057 Zobellia galactanivorans membrane protein YP_004738472.1 4769735 R 63186 CDS YP_004738473.1 340620020 10976524 4771047..4771310 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4771310 10976524 zobellia_4058 Zobellia galactanivorans membrane protein YP_004738473.1 4771047 D 63186 CDS YP_004738474.1 340620021 10976525 4771489..4773945 1 NC_015844.1 Contains fourteen transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4773945 10976525 zobellia_4059 Zobellia galactanivorans membrane protein YP_004738474.1 4771489 D 63186 CDS YP_004738475.1 340620022 10976526 4773984..4775255 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases. Localized in the cytoplasm.; Specificity unclear; glycosyltransferase 4775255 10976526 zobellia_4060 Zobellia galactanivorans glycosyltransferase YP_004738475.1 4773984 D 63186 CDS YP_004738476.1 340620023 10976528 4775255..4776718 1 NC_015844.1 Protein involved in the biosynthesis of an unknown exopolysaccharide; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Function unclear; polysaccharide biosynthesis protein 4776718 10976528 zobellia_4061 Zobellia galactanivorans polysaccharide biosynthesis protein YP_004738476.1 4775255 D 63186 CDS YP_004738477.1 340620024 10976529 4776836..4777618 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4777618 10976529 zobellia_4062 Zobellia galactanivorans hypothetical protein YP_004738477.1 4776836 D 63186 CDS YP_004738478.1 340620025 10976530 4777672..4778037 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4778037 10976530 zobellia_4063 Zobellia galactanivorans hypothetical protein YP_004738478.1 4777672 D 63186 CDS YP_004738479.1 340620026 10976531 4778053..4780356 1 NC_015844.1 Oxydoreductase which consists of a molybdopterin oxydoreductase domain; Binds 1 4Fe-4S cluster and uses molybdenum (molybdopterin) as cofactors; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family; Localized in the cytoplasm; Family membership; molybdopterin-containing oxidoreductase subunit alpha 4780356 10976531 zobellia_4064 Zobellia galactanivorans molybdopterin-containing oxidoreductase subunit alpha YP_004738479.1 4778053 D 63186 CDS YP_004738480.1 340620027 10976532 4780611..4780844 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 4780844 10976532 zobellia_4065 Zobellia galactanivorans hypothetical protein YP_004738480.1 4780611 D 63186 CDS YP_004738481.1 340620028 10976533 complement(4780930..4781151) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4781151 10976533 zobellia_4066 Zobellia galactanivorans hypothetical protein YP_004738481.1 4780930 R 63186 CDS YP_004738482.1 340620029 10976534 4781204..4781494 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 4781494 10976534 zobellia_4067 Zobellia galactanivorans hypothetical protein YP_004738482.1 4781204 D 63186 CDS YP_004738483.1 340620030 10976535 complement(4781856..4784633) 1 NC_015844.1 The UvrA protein belongs to the UvrABC repair system responsible of the recognition and processing of DNA lesions; UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate; Contains 2 ABC transporter domains; Belongs to the ABC transporter family; Localized in the cytoplasm; High confidence in function and specificity; excinuclease ABC subunit A 4784633 uvrA1 10976535 uvrA1 Zobellia galactanivorans excinuclease ABC subunit A YP_004738483.1 4781856 R 63186 CDS YP_004738484.1 340620031 10978731 4784879..4785460 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 4785460 10978731 zobellia_4069 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004738484.1 4784879 D 63186 CDS YP_004738485.1 340620032 10976536 complement(4785634..4785867) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4785867 10976536 zobellia_4070 Zobellia galactanivorans hypothetical protein YP_004738485.1 4785634 R 63186 CDS YP_004738486.1 340620033 10976538 4786082..4786663 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 4786663 10976538 zobellia_4071 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004738486.1 4786082 D 63186 CDS YP_004738487.1 340620034 10976539 complement(4786893..4787555) 1 NC_015844.1 Endonuclease III has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site. Required for the repair of both oxidative DNA damage and spontaneous mutagenic lesions. The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. Binds 1 4Fe-4S cluster. The cluster is not important for the catalytic activity, but which is probably involved in the proper positioning of the enzyme along the DNA strand. Localized in the cytoplasm.; High confidence in function and specificity; endonuclease III 4787555 nth 10976539 nth Zobellia galactanivorans endonuclease III YP_004738487.1 4786893 R 63186 CDS YP_004738488.1 340620035 10978277 4787598..4788050 1 NC_015844.1 Peroxiredoxins are thiol peroxidase. They are involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. The peroxidase reaction comprises two steps centered around a redox- active cysteine called the peroxidatic cysteine. It attacks the peroxide substrate and is oxidized to S-hydroxycysteine (a sulfenic acid). The second step is the regeneration of cysteine from S-hydroxycysteine. This regeneration is due to thiol-containing reductants such as thioredoxin. Localized in the cytoplasm.; High confidence in function and specificity; peroxiredoxin 4788050 10978277 zobellia_4073 Zobellia galactanivorans peroxiredoxin YP_004738488.1 4787598 D 63186 CDS YP_004738489.1 340620036 10976540 complement(4788105..4789571) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4789571 10976540 zobellia_4074 Zobellia galactanivorans hypothetical protein YP_004738489.1 4788105 R 63186 CDS YP_004738490.1 340620037 10976541 4789650..4790426 1 NC_015844.1 Conserved protein with a N-terminal domain belonging to the metallo-beta-lactamase superfamily and two rhodanese (thiosulfate sulfurtransferase) domains: one where the active-site cysteine residue is replaced by another aminoacid whereas the C-terminal domain displays the catalytic cysteine residue. contains various metallo-hydrolases including beta-lactamases, but also glyoxylases and arylsulfatases. The active site is characterized by several conserved histidines binding the catalytic zinc ions. The enzymes can bind one or two zinc ions. Localized in the cytoplasm.; Family membership; metallo-beta-lactamase superfamily protein 4790426 10976541 zobellia_4075 Zobellia galactanivorans metallo-beta-lactamase superfamily protein YP_004738490.1 4789650 D 63186 CDS YP_004738491.1 340620038 10976542 4790449..4790943 1 NC_015844.1 Contains a signal peptide cleaved between the residues 30 and 31; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4790943 10976542 zobellia_4076 Zobellia galactanivorans periplasmic protein YP_004738491.1 4790449 D 63186 CDS YP_004738492.1 340620039 10976543 complement(4790944..4791603) 1 NC_015844.1 This carboxylesterase hydrolyzes carboxylic ester bonds with relatively broad substrate specificity. It forms a homodimer. Each subunit consists of a central seven-stranded beta sheet flanked by six alpha helices (alpha/beta hydrolase fold). The structure reveals the catalytic triad Ser-His-Asp. Localized in the cytoplasm.; High confidence in function and specificity; carboxylesterase 4791603 estB 10976543 estB Zobellia galactanivorans carboxylesterase YP_004738492.1 4790944 R 63186 CDS YP_004738493.1 340620040 10977786 complement(4791600..4791923) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4791923 10977786 zobellia_4078 Zobellia galactanivorans membrane protein YP_004738493.1 4791600 R 63186 CDS YP_004738494.1 340620041 10976544 complement(4792013..4792327) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4792327 10976544 zobellia_4079 Zobellia galactanivorans membrane protein YP_004738494.1 4792013 R 63186 CDS YP_004738495.1 340620042 10976545 complement(4792353..4793615) 1 NC_015844.1 Dihydroorotase is involved in Pyrimidine biosynthesis. It catalyzes the reaction: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. It forms a homodimer and binds 2 zinc ions per subunit. Localized in the cytoplasm.; High confidence in function and specificity; dihydroorotase 4793615 pyrC 10976545 pyrC Zobellia galactanivorans dihydroorotase YP_004738495.1 4792353 R 63186 CDS YP_004738496.1 340620043 10978418 complement(4793612..4795561) 1 NC_015844.1 Membrane protein displaying a domain of unknown function DUF1550; Contains two N-terminal transmembrane helices; Localized in the cytoplasmic membrane; Family membership; membrane protein 4795561 10978418 zobellia_4081 Zobellia galactanivorans membrane protein YP_004738496.1 4793612 R 63186 CDS YP_004738497.1 340620044 10976547 complement(4795642..4796649) 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases.; Specificity unclear; glycosyltransferase 4796649 10976547 zobellia_4082 Zobellia galactanivorans glycosyltransferase YP_004738497.1 4795642 R 63186 CDS YP_004738498.1 340620045 10974054 complement(4796992..4797171) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4797171 10974054 zobellia_4084 Zobellia galactanivorans hypothetical protein YP_004738498.1 4796992 R 63186 CDS YP_004738499.1 340620046 10976549 4797244..4798425 1 NC_015844.1 Protein putatively involved in the coordinating multi-protein complex assemblies; Contains five WD40 repeats involved in the formation of circularised beta-propeller structure; Prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4798425 10976549 zobellia_4085 Zobellia galactanivorans lipoprotein YP_004738499.1 4797244 D 63186 CDS YP_004738500.1 340620047 10976550 4798464..4799045 1 NC_015844.1 The Crp/Fnr-type transcriptional regulators complexe with cyclic AMP and bind to operator sites near the promoter with a C-terminal HTH domain to regulate the transcription of several catabolite-sensitive operons; They predominantly act as transcription activators, but can also be important repressors, and respond to diverse intracellular and exogenous signals; Binds 1 4Fe-4S cluster per subunit; Localized in the cytoplasm; Family membership; Crp/Fnr-type transcriptional regulator 4799045 10976550 zobellia_4086 Zobellia galactanivorans Crp/Fnr-type transcriptional regulator YP_004738500.1 4798464 D 63186 CDS YP_004738501.1 340620048 10976551 4799127..4799624 1 NC_015844.1 The protein GlcG is a conserved protein iniatilly found in the glycolate utilization operon. Its exact function is unknown. Signal peptide cleaved between the residues 25 and 26. Localized in the periplasmic space.; Function unclear; protein glcG 4799624 glcG 10976551 glcG Zobellia galactanivorans protein glcG YP_004738501.1 4799127 D 63186 CDS YP_004738502.1 340620049 10977897 4799639..4801159 1 NC_015844.1 Contains a C-terminal stress responsive alpha-beta barrel domain; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 4801159 10977897 zobellia_4088 Zobellia galactanivorans hypothetical protein YP_004738502.1 4799639 D 63186 CDS YP_004738503.1 340620050 10976552 4801253..4801717 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 4801717 10976552 zobellia_4089 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004738503.1 4801253 D 63186 CDS YP_004738504.1 340620051 10976553 4801909..4802307 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4802307 10976553 zobellia_4090 Zobellia galactanivorans hypothetical protein YP_004738504.1 4801909 D 63186 CDS YP_004738505.1 340620052 10976555 4802387..4806718 1 NC_015844.1 Integral membrane protein possibly involved in cobalt, zinc and cadmium resistance that belongs to the acrB/acrD/acrF family; Contains 13 transmembrane segments and two large periplasmic domains (each exceeding 300 residues) between helices 1 and 2, and helices 7 and 8; Contains a C-terminal extension of 430 residues after the last transmembrane segment. The three transmembrane domains form a large, 30-wide central cavity that spans the cytoplasmic membrane and extends to the cytoplasm; Localized in the cytoplasmic membrane; Family membership; cation efflux transporter 4806718 czcA 10976555 czcA Zobellia galactanivorans cation efflux transporter YP_004738505.1 4802387 D 63186 CDS YP_004738506.1 340620053 10977710 4806729..4807877 1 NC_015844.1 Possibly involved in the cobalt, zinc and cadmium resistance; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters or a multidrug efflux transporter, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; Signal peptide of lipoprotein cleaved between the residues 19 and 20; Anchored in the cytoplasmic membrane by a N- terminal lipidic residue; Family membership; cation efflux system protein 4807877 czcB 10977710 czcB Zobellia galactanivorans cation efflux system protein YP_004738506.1 4806729 D 63186 CDS YP_004738507.1 340620054 10977711 complement(4807925..4808800) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4808800 10977711 zobellia_4093 Zobellia galactanivorans hypothetical protein YP_004738507.1 4807925 R 63186 CDS YP_004738508.1 340620055 10976556 complement(4808871..4809269) 1 NC_015844.1 protein of unknown function Localized in the cytoplasm; hypothetical protein 4809269 10976556 zobellia_4094 Zobellia galactanivorans hypothetical protein YP_004738508.1 4808871 R 63186 CDS YP_004738509.1 340620056 10976557 4809446..4810303 1 NC_015844.1 Conserved protein belonging to the Xylose isomerase-like TIM barrel family; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Family membership; xylose isomerase-like TIM barrel protein 4810303 10976557 zobellia_4095 Zobellia galactanivorans xylose isomerase-like TIM barrel protein YP_004738509.1 4809446 D 63186 CDS YP_004738510.1 340620057 10976558 4810534..4812918 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (23-92) and the Plug module (129-231) acting as a channel gate; The signal peptide is cleaved between the residues 18 and 19; Family membership; TonB-dependent Receptor 4812918 10976558 zobellia_4096 Zobellia galactanivorans TonB-dependent Receptor YP_004738510.1 4810534 D 63186 CDS YP_004738511.1 340620058 10976559 4812956..4814110 1 NC_015844.1 Contains four PepSY-associated transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4814110 10976559 zobellia_4097 Zobellia galactanivorans membrane protein YP_004738511.1 4812956 D 63186 CDS YP_004738512.1 340620059 10976560 4814307..4814666 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4814666 10976560 zobellia_4098 Zobellia galactanivorans hypothetical protein YP_004738512.1 4814307 D 63186 CDS YP_004738513.1 340620060 10976561 4814768..4815334 1 NC_015844.1 Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Contains a N-terminal transmembrane helix; Belongs to the thioredoxin family; Localized in the cytoplasmic membrane; Specificity unclear; thiol-disulfide oxidoreductase 4815334 10976561 zobellia_4099 Zobellia galactanivorans thiol-disulfide oxidoreductase YP_004738513.1 4814768 D 63186 CDS YP_004738514.1 340620061 10976562 complement(4815356..4815751) 1 NC_015844.1 Contains two transmembrane segments; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4815751 10976562 zobellia_4100 Zobellia galactanivorans membrane protein YP_004738514.1 4815356 R 63186 CDS YP_004738515.1 340620062 10976565 4815848..4816825 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 4816825 10976565 zobellia_4101 Zobellia galactanivorans AraC family transcriptional regulator YP_004738515.1 4815848 D 63186 CDS YP_004738516.1 340620063 10976566 complement(4816842..4817606) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4817606 10976566 zobellia_4102 Zobellia galactanivorans hypothetical protein YP_004738516.1 4816842 R 63186 CDS YP_004738517.1 340620064 10976567 complement(4817639..4818331) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase) encoded by a different gene of those that encode for the ABC transporter permease component (ABC membrane); Family membership; ABC transporter ATPase 4818331 10976567 zobellia_4103 Zobellia galactanivorans ABC transporter ATPase YP_004738517.1 4817639 R 63186 CDS YP_004738518.1 340620065 10976568 4818404..4818553 1 NC_015844.1 Hypothetical protein; hypothetical protein 4818553 10976568 zobellia_4104 Zobellia galactanivorans hypothetical protein YP_004738518.1 4818404 D 63186 CDS YP_004738519.1 340620066 10976569 4818540..4819139 1 NC_015844.1 GTP cyclohydrolase I catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate. FolE is a homodecamer, composed of a dimer of pentamers. It is an allosteric enzyme, whose activity is modulated by K(+), divalent cations, UTP, and tetrahydrobiopterin. Tetrahydrobiopterin is an inhibitor of this enzyme. Localized in the cytoplasm.; High confidence in function and specificity; GTP cyclohydrolase I 4819139 folE2 10976569 folE2 Zobellia galactanivorans GTP cyclohydrolase I YP_004738519.1 4818540 D 63186 CDS YP_004738520.1 340620067 10977839 4819219..4819524 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4819524 10977839 zobellia_4106 Zobellia galactanivorans membrane protein YP_004738520.1 4819219 D 63186 CDS YP_004738521.1 340620068 10976570 4819808..4821028 1 NC_015844.1 Sulfite oxidase catalyzes oxidation of sulphite to sulphate, using cytochrome c as the physiological electron acceptor. It forms a homodimer and the monomer consists of an N-terminal heme domain, Contains a twin arginine translocation pathway signal peptide cleaved between the residues 21 and 22; Localized in the periplasm; High confidence in function and specificity; sulfite oxidase 4821028 suoX 10976570 suoX Zobellia galactanivorans sulfite oxidase YP_004738521.1 4819808 D 63186 CDS YP_004738522.1 340620069 10978625 4821029..4821517 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4821517 10978625 zobellia_4108 Zobellia galactanivorans hypothetical protein YP_004738522.1 4821029 D 63186 CDS YP_004738523.1 340620070 10976571 4821563..4822459 1 NC_015844.1 Conserved protein belonging to the Fatty acid hydroxylase family. Members of this family are involved in cholesterol biosynthesis; Contains three transmembrane helices; Localized in the cytoplasmic membrane; Family membership; fatty acid hydroxylase family protein 4822459 10976571 zobellia_4109 Zobellia galactanivorans fatty acid hydroxylase family protein YP_004738523.1 4821563 D 63186 CDS YP_004738524.1 340620071 10976572 complement(4822504..4824723) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-101) and the Plug module (116-221) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 4824723 10976572 zobellia_4110 Zobellia galactanivorans TonB-dependent Receptor YP_004738524.1 4822504 R 63186 CDS YP_004738525.1 340620072 10976574 complement(4824777..4825106) 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4825106 10976574 zobellia_4111 Zobellia galactanivorans membrane protein YP_004738525.1 4824777 R 63186 CDS YP_004738526.1 340620073 10976575 complement(4825159..4825461) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4825461 10976575 zobellia_4112 Zobellia galactanivorans membrane protein YP_004738526.1 4825159 R 63186 CDS YP_004738527.1 340620074 10976576 complement(4825489..4825944) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4825944 10976576 zobellia_4113 Zobellia galactanivorans lipoprotein YP_004738527.1 4825489 R 63186 CDS YP_004738528.1 340620075 10976577 complement(4826049..4826681) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4826681 10976577 zobellia_4114 Zobellia galactanivorans hypothetical protein YP_004738528.1 4826049 R 63186 CDS YP_004738529.1 340620076 10976578 complement(4826961..4827911) 1 NC_015844.1 SerA catalyzes the conversion of 3-phosphoglycerate to 3-phosphonooxypyruvate, which is the first step of the serine biosynthesis pathway. SerA2 is composed of a substrate-binding domain (D-isomer specific 2-hydroxyacid dehydrogenase family) and a NAD-binding domain (Rossman fold). Localized in the cytoplasm; High confidence in function and specificity; D-3-phosphoglycerate dehydrogenase 4827911 serA2 10976578 serA2 Zobellia galactanivorans D-3-phosphoglycerate dehydrogenase YP_004738529.1 4826961 R 63186 CDS YP_004738530.1 340620077 10978581 complement(4828018..4829082) 1 NC_015844.1 Phosphoserine aminotransferase catalyzes the conversion of O-phospho-L-serine and oxoglutarate to 3-phosphonooxypyruvate and L-glutamate in the the major phosphorylated L-serine biosynthesis pathway; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; High confidence in function and specificity; phosphoserine aminotransferase 4829082 serC 10978581 serC Zobellia galactanivorans phosphoserine aminotransferase YP_004738530.1 4828018 R 63186 CDS YP_004738531.1 340620078 10978583 complement(4829159..4830199) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4830199 10978583 zobellia_4117 Zobellia galactanivorans hypothetical protein YP_004738531.1 4829159 R 63186 CDS YP_004738532.1 340620079 10976579 4830330..4830683 1 NC_015844.1 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. It binds two 4Fe-4S clusters; Localized in the cytoplasm; Function unclear; ferredoxin 4830683 fdx 10976579 fdx Zobellia galactanivorans ferredoxin YP_004738532.1 4830330 D 63186 CDS YP_004738533.1 340620080 10977823 complement(4830836..4834108) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins; The presence of an additional N-terminal extension that probably interacts with an anti-sigma factor, would be responsible of the signal transduction; Contains a carboxypeptidase regulatory domain (131-204), and a Plug module (221-343) acting as the channel gate; The signal peptide is cleaved between the residue 23 and 24; Family membership; TonB-dependent transducer 4834108 10977823 zobellia_4119 Zobellia galactanivorans TonB-dependent transducer YP_004738533.1 4830836 R 63186 CDS YP_004738534.1 340620081 10976580 complement(4834129..4835124) 1 NC_015844.1 This protein would be an intermediate between a TonB-dependant transducer and a ECF sigma factor in the transmission of a signal from outside towards the cytoplasm; Contains a C-terminal domain that displays similarities with the anti-sigma factors of the FecR/PupR family; The N-terminal domain, without similarities, would interact with the N-terminal extension found in the TonB-dependant transducers; Protein localized in the cytoplasmic membrane; Family membership; anti-sigma factor 4835124 10976580 zobellia_4120 Zobellia galactanivorans anti-sigma factor YP_004738534.1 4834129 R 63186 CDS YP_004738535.1 340620082 10976582 complement(4835181..4835759) 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 4835759 10976582 zobellia_4121 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004738535.1 4835181 R 63186 CDS YP_004738536.1 340620083 10976583 4836041..4837135 1 NC_015844.1 GTP-dependent nucleic acid-binding protein which may act as a translation factor; Uses magnesium ions as cofactor; Contains an N-terminal GTPase domain and a C-terminal TGS domain possibly involved in the nucleic acid binding; Belongs to the GTP1/OBG family, EngD subfamily; Localized in the cytoplasm; High confidence in function and specificity; GTP-dependent nucleic acid-binding protein EngD 4837135 engD 10976583 engD Zobellia galactanivorans GTP-dependent nucleic acid-binding protein EngD YP_004738536.1 4836041 D 63186 CDS YP_004738537.1 340620084 10977782 4837346..4839673 1 NC_015844.1 DNA helicase unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Contains a uvrD-like helicase ATP-binding domain and a uvrD-like helicase C-terminal domain; Belongs to the helicase family, UvrD subfamily Localized in the cytoplasm; High confidence in function and specificity; ATP-dependent DNA helicase 4839673 uvrD 10977782 uvrD Zobellia galactanivorans ATP-dependent DNA helicase YP_004738537.1 4837346 D 63186 CDS YP_004738538.1 340620085 10978735 4839872..4840492 1 NC_015844.1 Conserved protein belonging to the YrdC family . The YrdC protein from E. coli forms an alpha/beta twisted open-sheet structure composed of seven alpha helices and seven beta strands. YrdC was shown to binds double-stranded RNA. Its exact function is unclear. Localized in the cytoplasm.; Function unclear; YrdC family protein 4840492 10978735 zobellia_4124 Zobellia galactanivorans YrdC family protein YP_004738538.1 4839872 D 63186 CDS YP_004738539.1 340620086 10976584 complement(4840517..4841323) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4841323 10976584 zobellia_4125 Zobellia galactanivorans hypothetical protein YP_004738539.1 4840517 R 63186 CDS YP_004738540.1 340620087 10976585 4841477..4842874 1 NC_015844.1 Alpha-N-acetylgalactosaminidase catalyzes the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides. This enzyme belongs to the family 109 of the glycoside hydrolases. This hydrolase has an unusual catalytic mechanism involving NAD+ and Mn2+. The protein consists of two closely-associated domains. The N-terminal domain forms a NAD-binding Rossman fold. The C-terminal domain is the substrate-binding domain and adopts a alpha/beta fold. Features a twin-arginine signal peptide cleaved between the residues 28 and 29. Localized in the periplasm.; High confidence in function and specificity; alpha-N-acetylgalactosaminidase 4842874 nagA 10976585 nagA Zobellia galactanivorans alpha-N-acetylgalactosaminidase YP_004738540.1 4841477 D 63186 CDS YP_004738541.1 340620088 10978225 4842993..4844150 1 NC_015844.1 Conserved protein containing a von Willebrand factor type A (vWF) domain. vWF domains adopt a classic alpha/beta Rossmann fold and usually contains an unusual metal ion coordination site at its surface. Its exact function is unknown. Localized in the cytoplasm.; Family membership; von Willebrand factor type A protein 4844150 10978225 zobellia_4127 Zobellia galactanivorans von Willebrand factor type A protein YP_004738541.1 4842993 D 63186 CDS YP_004738542.1 340620089 10976586 4844221..4845690 1 NC_015844.1 Conserved protein belonging to the Magnesium chelatase, subunit ChlI family. Its function is unknown. Localized in the cytoplasm.; hypothetical protein 4845690 10976586 zobellia_4128 Zobellia galactanivorans hypothetical protein YP_004738542.1 4844221 D 63186 CDS YP_004738543.1 340620090 10976587 complement(4845762..4847126) 1 NC_015844.1 This conserved protein displays a N-terminal fibronectin type III domain followed by five Kelch repeats. The kelch motif forms a beta sheet and several of these sheets associate to form a beta propeller structure; Prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; Kelch repeat-containing protein 4847126 10976587 zobellia_4129 Zobellia galactanivorans Kelch repeat-containing protein YP_004738543.1 4845762 R 63186 CDS YP_004738544.1 340620091 10976588 4847515..4849866 1 NC_015844.1 Alginate lyase catalyzes the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. It belongs to the family 6 of the polysaccharide lyases. Features an uncleaved signal peptide.; High confidence in function and specificity; alginate lyase 4849866 alyA4 10976588 alyA4 Zobellia galactanivorans alginate lyase YP_004738544.1 4847515 D 63186 CDS YP_004738545.1 340620092 10977514 4849883..4850941 1 NC_015844.1 Alginate lyase catalyzes the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends; Belongs to the family 7 of the polysaccharide lyases (PL7); Contains a putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; High confidence in function and specificity; alginate lyase 4850941 alyA5 10977514 alyA5 Zobellia galactanivorans alginate lyase YP_004738545.1 4849883 D 63186 CDS YP_004738546.1 340620093 10977515 4851091..4853424 1 NC_015844.1 Alginate lyase catalyzes the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. It belongs to the family 6 of the polysaccharide lyases. Features a signal peptide cleaved between residues 22 and 23. Localized in the periplasm.; High confidence in function and specificity; alginate lyase 4853424 alyA6 10977515 alyA6 Zobellia galactanivorans alginate lyase YP_004738546.1 4851091 D 63186 CDS YP_004738547.1 340620094 10977516 complement(4853488..4854981) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two transmembrane segments and a HAMP domain; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 4854981 10977516 zobellia_4133 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738547.1 4853488 R 63186 CDS YP_004738548.1 340620095 10976590 complement(4854978..4855679) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity (here a winged-helix DNA-binding domain) that acts as transcriptional regulator; Family membership; two-component system-response regulator 4855679 10976590 zobellia_4134 Zobellia galactanivorans two-component system-response regulator YP_004738548.1 4854978 R 63186 CDS YP_004738549.1 340620096 10976591 4856065..4856955 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 4856955 10976591 zobellia_4135 Zobellia galactanivorans lipoprotein YP_004738549.1 4856065 D 63186 CDS YP_004738550.1 340620097 10976592 complement(4857021..4857503) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4857503 10976592 zobellia_4136 Zobellia galactanivorans membrane protein YP_004738550.1 4857021 R 63186 CDS YP_004738551.1 340620099 10976593 complement(4857701..4858213) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4858213 10976593 zobellia_4138 Zobellia galactanivorans membrane protein YP_004738551.1 4857701 R 63186 CDS YP_004738552.1 340620098 10976594 4858212..4859009 1 NC_015844.1 tRNA pseudouridine synthase is responsible for the formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer-RNAs. Pseudouridine is an isomer of uridine (5-(beta-D- ribofuranosyl) uracil, and id the most abundant modified nucleoside found in all cellular RNAs. TruA contains one atom of zinc essential for its native conformation and tRNA recognition and has a strictly conserved aspartic acid that is likely to be involved in catalysis. It forms a dimer. Localized in the cytoplasm.; High confidence in function and specificity; tRNA pseudouridine synthase A 4859009 truA2 10976594 truA2 Zobellia galactanivorans tRNA pseudouridine synthase A YP_004738552.1 4858212 D 63186 CDS YP_004738553.1 340620100 10978702 4859050..4860141 1 NC_015844.1 CorA is a membrane protein which mediates influx of magnesium ions. It forms a homotetramer. Features two C-terminal transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; magnesium transport protein CorA 4860141 corA 10978702 corA Zobellia galactanivorans magnesium transport protein CorA YP_004738553.1 4859050 D 63186 CDS YP_004738554.1 340620101 10977668 4860215..4861012 1 NC_015844.1 Conserved protein belonging to the family S9 of the serine peptidases. The active site residues are in the order Ser, Asp, His in the sequence. Its exact specificity is unknown. Features a signal peptide cleaved between the residues 22 and 23. Localized in the periplasm.; Specificity unclear; serine peptidase 4861012 10977668 zobellia_4140 Zobellia galactanivorans serine peptidase YP_004738554.1 4860215 D 63186 CDS YP_004738555.1 340620102 10976596 complement(4861018..4861902) 1 NC_015844.1 The cysteine synthase is the enzyme responsible for the formation of cysteine from O-acetyl-serine and hydrogen sulfide with the concomitant release of acetic acid. Uses the pyridoxal phosphate as cofactor (vitamin B6) attached to a conserved lysine residue. Belongs to the cysteine synthase/cystathionine beta-synthase family; Localized in the cytoplasm.; High confidence in function and specificity; cysteine synthase B 4861902 cysM 10976596 cysM Zobellia galactanivorans cysteine synthase B YP_004738555.1 4861018 R 63186 CDS YP_004738556.1 340620103 10977707 complement(4861892..4862686) 1 NC_015844.1 Serine O-acetyltransferase is involved in L-cyteine biosynthesis. It catalyzes the reaction: Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine. Localized in the cytoplasm.; High confidence in function and specificity; serine O-acetyltransferase 4862686 cysE 10977707 cysE Zobellia galactanivorans serine O-acetyltransferase YP_004738556.1 4861892 R 63186 CDS YP_004738557.1 340620104 10977701 4862780..4863460 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4863460 10977701 zobellia_4143 Zobellia galactanivorans hypothetical protein YP_004738557.1 4862780 D 63186 CDS YP_004738558.1 340620105 10976597 complement(4863449..4863886) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 4863886 10976597 zobellia_4144 Zobellia galactanivorans hypothetical protein YP_004738558.1 4863449 R 63186 CDS YP_004738559.1 340620106 10976598 4864010..4865365 1 NC_015844.1 Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm.; Family membership; succinate-semialdehyde dehydrogenase 4865365 gabD 10976598 gabD Zobellia galactanivorans succinate-semialdehyde dehydrogenase YP_004738559.1 4864010 D 63186 CDS YP_004738560.1 340620107 10977873 4865606..4866205 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 4866205 10977873 zobellia_4146 Zobellia galactanivorans hypothetical protein YP_004738560.1 4865606 D 63186 CDS YP_004738561.1 340620108 10976599 complement(4866229..4866324) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4866324 10976599 zobellia_4147 Zobellia galactanivorans hypothetical protein YP_004738561.1 4866229 R 63186 CDS YP_004738562.1 340620109 10976600 4866347..4867243 1 NC_015844.1 Conserved protein belonging to the DUF72 family. Localized in the cytoplasm.; Family membership; hypothetical protein 4867243 10976600 zobellia_4148 Zobellia galactanivorans hypothetical protein YP_004738562.1 4866347 D 63186 CDS YP_004738563.1 340620110 10976601 4867301..4867696 1 NC_015844.1 Acyl-CoA thioester hydrolase yciA catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA. Localized in the cytoplasm.; High confidence in function and specificity; acyl-CoA thioester hydrolase yciA 4867696 yciA 10976601 yciA Zobellia galactanivorans acyl-CoA thioester hydrolase yciA YP_004738563.1 4867301 D 63186 CDS YP_004738564.1 340620111 10978781 complement(4867693..4869024) 1 NC_015844.1 Dipeptidase hydrolyzes a wide range of dipeptides. Binds two catalytic zinc ions; Belongs to the family M19 of the peptidases; Contains a putative lipoprotein signal peptide cleaved between the residues 29 and 30; Possibly localized in the outer membrane; Specificity unclear; dipeptidase 9 4869024 10978781 zobellia_4150 Zobellia galactanivorans dipeptidase 9 YP_004738564.1 4867693 R 63186 CDS YP_004738565.1 340620112 10976603 4869176..4869907 1 NC_015844.1 Histidine-containing phosphotransfer (HPt)protein mediates phosphotransfer reactions in the two-component signaling systems. Such a protein consists of six alpha helices containing a four-helix bundle-folding. Localized in the cytoplasm.; Specificity unclear; histidine-containing phosphotransfer protein 4869907 10976603 zobellia_4151 Zobellia galactanivorans histidine-containing phosphotransfer protein YP_004738565.1 4869176 D 63186 CDS YP_004738566.1 340620113 10976604 4869916..4870287 1 NC_015844.1 This protein is a isolated response regulator receiver which is phosphorytaled by an histidine protein kinase environmental sensor. Belongs to the CheY family. Localized in the cytoplasm.; Specificity unclear; response regulator receiver 4870287 10976604 zobellia_4152 Zobellia galactanivorans response regulator receiver YP_004738566.1 4869916 D 63186 CDS YP_004738567.1 340620114 10976605 4870289..4873087 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4873087 10976605 zobellia_4153 Zobellia galactanivorans membrane protein YP_004738567.1 4870289 D 63186 CDS YP_004738568.1 340620115 10976606 4873080..4874510 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases. It is closely related to PgaC (Biofilm PGA synthesis N-glycosyltransferase) which is involved in E. coli in the biosynthesis of an exopolysaccharide constituted of N-acetyl-D-glucosamines linked by beta-(1,6) glycosidic bonds. Integral membrane protein with five transmembrane helices.; Specificity unclear; glycosyltransferase 4874510 10976606 zobellia_4154 Zobellia galactanivorans glycosyltransferase YP_004738568.1 4873080 D 63186 CDS YP_004738569.1 340620116 10976607 4874519..4876876 1 NC_015844.1 Protein that could belong to the akaline phosphatase superfamily; Contains five N-terminal transmembrane segments and three C-terminal TPR repeats involved in proteinprotein interactions and the assembly of multiprotein complexes; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 4876876 10976607 zobellia_4155 Zobellia galactanivorans hypothetical protein YP_004738569.1 4874519 D 63186 CDS YP_004738570.1 340620117 10976608 4876903..4878180 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4878180 10976608 zobellia_4156 Zobellia galactanivorans periplasmic protein YP_004738570.1 4876903 D 63186 CDS YP_004738571.1 340620118 10976609 4878599..4878697 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 4878697 10976609 zobellia_4157 Zobellia galactanivorans hypothetical protein YP_004738571.1 4878599 D 63186 CDS YP_004738572.1 340620119 10976610 complement(4878919..4879782) 1 NC_015844.1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. RpoD is usually the primary sigma factor in bacteria. Belongs to the sigma-70 factor family. Localized in the cytoplasm.; High confidence in function and specificity; RNA polymerase sigma factor rpoD 4879782 rpoD2 10976610 rpoD2 Zobellia galactanivorans RNA polymerase sigma factor rpoD YP_004738572.1 4878919 R 63186 CDS YP_004738573.1 340620120 10978528 4879954..4880463 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4880463 10978528 zobellia_4159 Zobellia galactanivorans hypothetical protein YP_004738573.1 4879954 D 63186 CDS YP_004738574.1 340620121 10976611 4880466..4881395 1 NC_015844.1 Glyoxylate/hydroxypyruvate reductase A catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively; Contains a glycine-rich region located in the central section corresponding to the NAD-binding domain; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity; glyoxylate/hydroxypyruvate reductase A 4881395 ghrA 10976611 ghrA Zobellia galactanivorans glyoxylate/hydroxypyruvate reductase A YP_004738574.1 4880466 D 63186 CDS YP_004738575.1 340620122 10977896 4881595..4883106 1 NC_015844.1 Helicases are involved in unwinding nucleic acids; Contains a N-terminal ResIII domain or a DEAD domain and a C-terminal helicase domain; Belongs to the superfamily II of helicases; Localized in the cytoplasm; Family membership; ATP-dependent helicase 4883106 10977896 zobellia_4161 Zobellia galactanivorans ATP-dependent helicase YP_004738575.1 4881595 D 63186 CDS YP_004738576.1 340620123 10976613 4883151..4884395 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds; Belongs to the family 4 of the glycosyltransferases (GT4); Localized in the cytoplasm; Specificity unclear; glycosyltransferase 4884395 10976613 zobellia_4162 Zobellia galactanivorans glycosyltransferase YP_004738576.1 4883151 D 63186 CDS YP_004738577.1 340620124 10976614 complement(4884428..4884826) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity that acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership; two-component system-response regulator, receiver domain 4884826 10976614 zobellia_4163 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004738577.1 4884428 R 63186 CDS YP_004738578.1 340620125 10976615 complement(4884841..4887081) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two N-terminal PAS/PAC domains involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 4887081 10976615 zobellia_4164 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738578.1 4884841 R 63186 CDS YP_004738579.1 340620126 10976616 complement(4887203..4887601) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. Usually, the protein consists of an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity that acts as transcriptional regulator. This sequence corresponds to the receiver domain only; Family membership; two-component system-response regulator, receiver domain 4887601 10976616 zobellia_4165 Zobellia galactanivorans two-component system-response regulator, receiver domain YP_004738579.1 4887203 R 63186 CDS YP_004738580.1 340620127 10976617 complement(4887608..4890229) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains three N-terminal PAS/PAC domains involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 4890229 10976617 zobellia_4166 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738580.1 4887608 R 63186 CDS YP_004738581.1 340620128 10976618 4890577..4891425 1 NC_015844.1 Also called dihydroxynaphthoic acid synthetase (DHNA), this enzyme converts the O-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoic acid (DHNA) in the fifth step of the menaquinone (vitamin K2) biosynthesis pathway from chorismate; Belongs to the enoyl-CoA hydratase/isomerase family; Localized in the cytoplasm; High confidence in function and specificity; Naphthoate synthase 4891425 menB 10976618 menB Zobellia galactanivorans Naphthoate synthase YP_004738581.1 4890577 D 63186 CDS YP_004738582.1 340620129 10978141 complement(4891707..4893035) 1 NC_015844.1 Protein belonging to the family 12 of Serine peptidases (S12). Could be a beta-lactamase classified as S12 non-peptidase homologues. However, the active site residues Ser and Lys that form the catalytic dyad are found in the motif Ser-Xaa-Thr-Lys; Contains a N-terminal transmembrane segment and a C-terminal beta-lactamase domain; Localized in the cytoplasmic membrane; Function unclear; serine peptidase 4893035 10978141 zobellia_4168 Zobellia galactanivorans serine peptidase YP_004738582.1 4891707 R 63186 CDS YP_004738583.1 340620130 10976619 4893133..4894092 1 NC_015844.1 Glyoxylate reductase converts, in presence of NAD+, the Glycolate into glyoxylate. GyaR is involved in the glyoxylate metabolism (conversion of lipids into glucids); Contains a glycine-rich region located in the central section corresponding to the NAD-binding domain; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity; glyoxylate reductase 4894092 gyaR 10976619 gyaR Zobellia galactanivorans glyoxylate reductase YP_004738583.1 4893133 D 63186 CDS YP_004738584.1 340620131 10977957 4894126..4894554 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4894554 10977957 zobellia_4170 Zobellia galactanivorans periplasmic protein YP_004738584.1 4894126 D 63186 CDS YP_004738585.1 340620132 10976621 4894551..4895249 1 NC_015844.1 Amidase catalyzes the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3. The specificity of this enzyme is unknown. Belongs to a protein family including N-acetylmuramoyl-L-alanine amidase. Features an uncleaved signal peptide. Localized in the cytoplasmic membrane.; Specificity unclear; amidase 4895249 10976621 zobellia_4171 Zobellia galactanivorans amidase YP_004738585.1 4894551 D 63186 CDS YP_004738586.1 340620133 10976622 4895246..4896712 1 NC_015844.1 Peptidase family M14 contains mainly metallocarboxypeptidases. The single catalytic zinc ion is tetrahedrally coordinated by two histidines and a glutamate, as well as a water molecule. One of the histidines and the glutamate occur in the motif His-Xaa-Xaa-Glu. Features a signal peptide cleaved between the residues 18 and 19. Localized in the periplasm.; Specificity unclear; metallopeptidase 4 4896712 10976622 zobellia_4172 Zobellia galactanivorans metallopeptidase 4 YP_004738586.1 4895246 D 63186 CDS YP_004738587.1 340620134 10976623 complement(4896726..4896929) 1 NC_015844.1 Contains a transmembrane helix; Putatively localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 4896929 10976623 zobellia_4173 Zobellia galactanivorans hypothetical protein YP_004738587.1 4896726 R 63186 CDS YP_004738588.1 340620135 10976624 complement(4897126..4897953) 1 NC_015844.1 Protein containing a C-terminal OmpA-like domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the outer membrane; Family membership; OmpA-like lipoprotein 4897953 10976624 zobellia_4174 Zobellia galactanivorans OmpA-like lipoprotein YP_004738588.1 4897126 R 63186 CDS YP_004738589.1 340620136 10976625 complement(4898179..4899264) 1 NC_015844.1 Conserved protein containing a von Willebrand factor type A (vWF) domain. vWF domains adopt a classic alpha/beta Rossmann fold and usually contains an unusual metal ion coordination site at its surface. Its exact function is unknown. Features a signal peptide cleaved between the residues 23 and 24. Localized in the periplasm.; Family membership; von Willebrand factor type A protein 4899264 10976625 zobellia_4175 Zobellia galactanivorans von Willebrand factor type A protein YP_004738589.1 4898179 R 63186 CDS YP_004738590.1 340620137 10976626 4899556..4900017 1 NC_015844.1 Isoquinoline 1-oxidoreductase catalyzes the hydroxylation of isoquinoline to 1-oxo-1,2-dihydroisoquinoline with subsequent reduction of a suitable electron acceptor utilizing H2O as the source of the oxygen atom incorporated into substrate. It is a heterodimeric molybdo-iron-sulfur protein, composed of a small subunit and a large subunit (IorB). IorA binds a [2Fe-2S] cluster as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; isoquinoline 1-oxidoreductase subunit alpha 4900017 iorA 10976626 iorA Zobellia galactanivorans isoquinoline 1-oxidoreductase subunit alpha YP_004738590.1 4899556 D 63186 CDS YP_004738591.1 340620138 10978040 4900078..4902306 1 NC_015844.1 Isoquinoline 1-oxidoreductase catalyzes the hydroxylation of isoquinoline to 1-oxo-1,2-dihydroisoquinoline with subsequent reduction of a suitable electron acceptor utilizing H2O as the source of the oxygen atom incorporated into substrate. It is a heterodimeric molybdo-iron-sulfur protein, composed of a small subunit (IorA) and a large subunit . IorB contains a molybdopterin binding domain and an alpha/beta hammerhead domain. Uses molybdopterin as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; isoquinoline 1-oxidoreductase subunit beta 4902306 iorB 10978040 iorB Zobellia galactanivorans isoquinoline 1-oxidoreductase subunit beta YP_004738591.1 4900078 D 63186 CDS YP_004738592.1 340620139 10978041 4902361..4903371 1 NC_015844.1 Conserved protein belonging to the XdhC/PucA family. XhdhC in E. coli and PucA in B. subtilis are involved in molybdenum cofactor insertion into xanthine dehydrogenase. Localized in the cytoplasm.; Function unclear; XdhC family protein 4903371 10978041 zobellia_4178 Zobellia galactanivorans XdhC family protein YP_004738592.1 4902361 D 63186 CDS YP_004738593.1 340620140 10976627 4903371..4903985 1 NC_015844.1 Conserved protein; Function unclear; PucB-like protein 4903985 10976627 zobellia_4179 Zobellia galactanivorans PucB-like protein YP_004738593.1 4903371 D 63186 CDS YP_004738594.1 340620141 10976628 4903969..4905054 1 NC_015844.1 This protein belongs to the amidohydrolase family. This family is included in the metal-dependent hydrolase superfamily; Adopts a TIM-barrel fold; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Family membership; amidohydrolase 4905054 10976628 zobellia_4180 Zobellia galactanivorans amidohydrolase YP_004738594.1 4903969 D 63186 CDS YP_004738595.1 340620142 10976630 4905156..4906172 1 NC_015844.1 This peptidase belongs to the family 4 of the metallopeptidases (M4). The conserved catalytic motif is HEXXE, in which the histidines are zinc ligands and the glutamate is a catalytic residue. The zinc ion is also bound by a second glutamate, 20-33 residues C-terminal to the HEXXH motif, and by an activated water molecule which forms the nucleophile in catalysis; Possibly localized in the cytoplasm; Specificity unclear; metallopeptidase 4906172 10976630 zobellia_4181 Zobellia galactanivorans metallopeptidase YP_004738595.1 4905156 D 63186 CDS YP_004738596.1 340620143 10976631 4906172..4906438 1 NC_015844.1 Hypothetical protein; hypothetical protein 4906438 10976631 zobellia_4182 Zobellia galactanivorans hypothetical protein YP_004738596.1 4906172 D 63186 CDS YP_004738597.1 340620144 10976632 4906451..4907134 1 NC_015844.1 Catalyzes the hydrolytic dehalogenation of small L-2-haloalkanoic acids to yield the corresponding D-2-hydroxyalkanoic acids. Active with 2-halogenated carboxylic acids and converts only the L-isomer of 2- chloropropionic acid with inversion of configuration to produce D-lactate; Belongs to the HAD-like hydrolase superfamily; Localized in the cytoplasm; High confidence in function and specificity; (S)-2-haloacid dehalogenase 4907134 dhlB 10976632 dhlB Zobellia galactanivorans (S)-2-haloacid dehalogenase YP_004738597.1 4906451 D 63186 CDS YP_004738598.1 340620145 10977743 complement(4907141..4907371) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4907371 10977743 zobellia_4184 Zobellia galactanivorans hypothetical protein YP_004738598.1 4907141 R 63186 CDS YP_004738599.1 340620146 10976633 complement(4907556..4908188) 1 NC_015844.1 Transcriptional regulator involved in the repression and/or the positive regulation of genes encoding for enzymes; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcriptional regulators, involved in the binding of the protein to the operator sequences in the DNA. At the C-terminus there is an effector- binding/oligomerisation domain; Localized in the cytoplasm; Family membership; GntR family transcriptional regulator 4908188 10976633 zobellia_4185 Zobellia galactanivorans GntR family transcriptional regulator YP_004738599.1 4907556 R 63186 CDS YP_004738600.1 340620147 10976634 complement(4908179..4908334) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4908334 10976634 zobellia_4186 Zobellia galactanivorans hypothetical protein YP_004738600.1 4908179 R 63186 CDS YP_004738601.1 340620148 10976635 4908362..4909189 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4909189 10976635 zobellia_4187 Zobellia galactanivorans hypothetical protein YP_004738601.1 4908362 D 63186 CDS YP_004738602.1 340620149 10976636 4909644..4910099 1 NC_015844.1 Cold shock proteins (CSPs) help the cell to survive in temperatures lower than optimum growth temperature. CSPs may act as RNA chaperones by destabilizing RNA secondary structures, regulating ribosomal translation, rate of mRNA degradation and termination of transcription; Contains a 'cold-shock domain' (CSD) involved in the single-strand nucleic-acid binding; Localized in the cytoplasm; High confidence in function and specificity; cold shock protein 4910099 cspA4 10976636 cspA4 Zobellia galactanivorans cold shock protein YP_004738602.1 4909644 D 63186 CDS YP_004738603.1 340620150 10977688 4910141..4910848 1 NC_015844.1 Protein belonging to the DUF1080 family; Signal peptide cleaved between the residues 30 and 31; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4910848 10977688 zobellia_4189 Zobellia galactanivorans periplasmic protein YP_004738603.1 4910141 D 63186 CDS YP_004738604.1 340620151 10976637 complement(4910854..4911447) 1 NC_015844.1 Enzyme responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA by rotation of the C1'-N-1 glycosidic bond of uridine to a C1'-C5; Belongs to the pseudouridine synthase RsuA family; localized in the cytoplasm; High confidence in function and specificity; ribosomal large subunit pseudouridine synthase E 4911447 rluE 10976637 rluE Zobellia galactanivorans ribosomal large subunit pseudouridine synthase E YP_004738604.1 4910854 R 63186 CDS YP_004738605.1 340620152 10978472 4911574..4912203 1 NC_015844.1 Conserved protein belonging to the NAD dependent epimerase/dehydratase family; Localized in the cytoplasm; Family membership; NAD dependent epimerase/dehydratase family protein 4912203 10978472 zobellia_4191 Zobellia galactanivorans NAD dependent epimerase/dehydratase family protein YP_004738605.1 4911574 D 63186 CDS YP_004738606.1 340620153 10976639 4912298..4913191 1 NC_015844.1 Conserved protein belonging to the Xylose isomerase-like TIM barrel family; Localized in the cytoplasm.; Family membership; xylose isomerase-like TIM barrel protein 4913191 10976639 zobellia_4192 Zobellia galactanivorans xylose isomerase-like TIM barrel protein YP_004738606.1 4912298 D 63186 CDS YP_004738607.1 340620154 10976640 4913202..4914404 1 NC_015844.1 L-sorbosone dehydrogenase converts L-sorbosone into 2-keto-L-gulonic acid (2KGA); Uses one of four different quinone as cofactors for the oxidation of sorbosone; Belongs to the Quinoprotein dehydrogenases family; Lipoprotein with a signal peptide cleaved between the residues 20 and 21; Putatively localized in the outer membrane; High confidence in function and specificity; L-sorbosone dehydrogenase 4914404 10976640 zobellia_4193 Zobellia galactanivorans L-sorbosone dehydrogenase YP_004738607.1 4913202 D 63186 CDS YP_004738608.1 340620155 10976641 4914642..4914968 1 NC_015844.1 Hypothetical protein; hypothetical protein 4914968 10976641 zobellia_4194 Zobellia galactanivorans hypothetical protein YP_004738608.1 4914642 D 63186 CDS YP_004738609.1 340620156 10976642 4915257..4916372 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4916372 10976642 zobellia_4195 Zobellia galactanivorans hypothetical protein YP_004738609.1 4915257 D 63186 CDS YP_004738610.1 340620157 10976643 4916410..4916853 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 4916853 10976643 zobellia_4196 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004738610.1 4916410 D 63186 CDS YP_004738611.1 340620158 10976644 4917098..4917799 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4917799 10976644 zobellia_4197 Zobellia galactanivorans hypothetical protein YP_004738611.1 4917098 D 63186 CDS YP_004738612.1 340620159 10976645 4917814..4918683 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4918683 10976645 zobellia_4198 Zobellia galactanivorans hypothetical protein YP_004738612.1 4917814 D 63186 CDS YP_004738613.1 340620160 10976646 4918715..4919317 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 4919317 10976646 zobellia_4199 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004738613.1 4918715 D 63186 CDS YP_004738614.1 340620161 10976647 4919547..4919954 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4919954 10976647 zobellia_4200 Zobellia galactanivorans hypothetical protein YP_004738614.1 4919547 D 63186 CDS YP_004738615.1 340620162 10976649 4920036..4921784 1 NC_015844.1 Possible glycosyde hydrolase belonging to the family 9 of glycoside hydrolases (GH9); Signal peptide cleaved between the residues 25 and 26; Localized in the periplasmic space; Family membership; glycoside hydrolase 4921784 10976649 zobellia_4201 Zobellia galactanivorans glycoside hydrolase YP_004738615.1 4920036 D 63186 CDS YP_004738616.1 340620163 10976650 4922218..4922568 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 4922568 10976650 zobellia_4202 Zobellia galactanivorans hypothetical protein YP_004738616.1 4922218 D 63186 CDS YP_004738617.1 340620164 10976651 complement(4922793..4924412) 1 NC_015844.1 The beta-agarase A is a modular protein that hydrolyses the 1,4-beta-D-galactosidic linkages in agarose, giving the tetramer and hexamer as the predominant products; Contains a N-terminal catalytic module (20-295) that belongs to the family 16 of glycoside hydrolases (GH16) and two C-terminal domains (296-437 and 438-539) of unknown fuction; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space then secreted in the extracellular medium; High confidence in function and specificity; beta-agarase A 4924412 agaA 10976651 agaA Zobellia galactanivorans beta-agarase A YP_004738617.1 4922793 R 63186 CDS YP_004738618.1 340620165 10977483 complement(4924887..4926974) 1 NC_015844.1 Conserved protein containing seven MORN repeats; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Function unclear; MORN repeat protein 4926974 10977483 zobellia_4204 Zobellia galactanivorans MORN repeat protein YP_004738618.1 4924887 R 63186 CDS YP_004738619.1 340620166 10976652 4927255..4927542 1 NC_015844.1 Hypothetical protein; hypothetical protein 4927542 10976652 zobellia_4205 Zobellia galactanivorans hypothetical protein YP_004738619.1 4927255 D 63186 CDS YP_004738620.1 340620167 10976653 complement(4927646..4930312) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains four N-terminal PAS/PAC domains involved in many signalling proteins where they are used as a signal sensor domain; Seems localized in the cytoplasm; Family membership; two-component system-sensor histidine kinase 4930312 10976653 zobellia_4206 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738620.1 4927646 R 63186 CDS YP_004738621.1 340620168 10976654 4930389..4930622 1 NC_015844.1 contains one transmembrane segment; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 4930622 10976654 zobellia_4207 Zobellia galactanivorans hypothetical protein YP_004738621.1 4930389 D 63186 CDS YP_004738622.1 340620169 10976655 4930753..4931106 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 4931106 10976655 zobellia_4208 Zobellia galactanivorans hypothetical protein YP_004738622.1 4930753 D 63186 CDS YP_004738623.1 340620170 10976656 4931246..4931992 1 NC_015844.1 Putatively contains a C-terminal Globin-like domain; Probably localized in the cytoplasm; hypothetical protein 4931992 10976656 zobellia_4209 Zobellia galactanivorans hypothetical protein YP_004738623.1 4931246 D 63186 CDS YP_004738624.1 340620171 10976657 4932068..4932643 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Hypothetical protein; hypothetical protein 4932643 10976657 zobellia_4210 Zobellia galactanivorans hypothetical protein YP_004738624.1 4932068 D 63186 CDS YP_004738625.1 340620172 10976659 4932882..4933796 1 NC_015844.1 Glutaminase catalyzes the reaction: L-glutamine + H2O = L-glutamate + NH3. Localized in the cytoplasm.; High confidence in function and specificity; glutaminase 4933796 glsA 10976659 glsA Zobellia galactanivorans glutaminase YP_004738625.1 4932882 D 63186 CDS YP_004738626.1 340620173 10977928 4934157..4934747 1 NC_015844.1 Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Hypothetical protein; TetR family transcriptional regulator 4934747 10977928 zobellia_4212 Zobellia galactanivorans TetR family transcriptional regulator YP_004738626.1 4934157 D 63186 CDS YP_004738627.1 340620174 10976660 4934781..4936046 1 NC_015844.1 3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP synthase 4936046 fabB6 10976660 fabB6 Zobellia galactanivorans 3-oxoacyl-ACP synthase YP_004738627.1 4934781 D 63186 CDS YP_004738628.1 340620175 10977798 4936608..4937249 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4937249 10977798 zobellia_4214 Zobellia galactanivorans hypothetical protein YP_004738628.1 4936608 D 63186 CDS YP_004738629.1 340620176 10976661 4937486..4938097 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 4938097 10976661 zobellia_4215 Zobellia galactanivorans hypothetical protein YP_004738629.1 4937486 D 63186 CDS YP_004738630.1 340620177 10976662 4938319..4939371 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Hypothetical protein; hypothetical protein 4939371 10976662 zobellia_4216 Zobellia galactanivorans hypothetical protein YP_004738630.1 4938319 D 63186 CDS YP_004738631.1 340620178 10976663 4939620..4940420 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4940420 10976663 zobellia_4217 Zobellia galactanivorans periplasmic protein YP_004738631.1 4939620 D 63186 CDS YP_004738632.1 340620179 10976664 4940694..4941419 1 NC_015844.1 Siderophore-interacting proteins are involved in intracellular removal of iron from iron-siderophore complex. Induced by iron starvation; Contains a N-terminal FAD-binding domain; Localized in the cytoplasm; High confidence in function and specificity; siderophore-interacting protein 4941419 viuB 10976664 viuB Zobellia galactanivorans siderophore-interacting protein YP_004738632.1 4940694 D 63186 CDS YP_004738633.1 340620180 10978745 4941576..4942349 1 NC_015844.1 Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4942349 10978745 zobellia_4219 Zobellia galactanivorans membrane protein YP_004738633.1 4941576 D 63186 CDS YP_004738634.1 340620181 10976665 complement(4942353..4942727) 1 NC_015844.1 Ferric uptake regulation protein is a transcriptional regulator that acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed metal ion-responsive genes. It regulates the expression of several outer- membrane proteins including the iron transport operon; Belongs to the Fur family; Localized in the cytoplasm; High confidence in function and specificity; ferric uptake regulation protein 4942727 furA2 10976665 furA2 Zobellia galactanivorans ferric uptake regulation protein YP_004738634.1 4942353 R 63186 CDS YP_004738635.1 340620182 10977871 4942847..4943755 1 NC_015844.1 The active site of this enzyme is a redox-active disulfide bond. TrxB uses the FAD to shuttle reducing equivalents from NAD(P)H to a Cys residue that is usually a part of a redox-active disulphide bridge. In a second step, the reduced disulphide reduces the substrate; Acts as an homodimer and binds one FAD molecule per subunit; Contains a N-terminal transmembrane segment; Belongs to the class 2 of pyridine nucleotide-disulphide reductases (PNDR); Localized in the cytoplasmic membrane; High confidence in function and specificity; thioredoxin reductase 4943755 trxB4 10977871 trxB4 Zobellia galactanivorans thioredoxin reductase YP_004738635.1 4942847 D 63186 CDS YP_004738636.1 340620183 10978712 4943778..4944023 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 4944023 10978712 zobellia_4222 Zobellia galactanivorans hypothetical protein YP_004738636.1 4943778 D 63186 CDS YP_004738637.1 340620184 10976667 4944035..4944637 1 NC_015844.1 SAM-dependent methyltransferase transfers from the ubiquitous S-adenosyl-L-methionine (SAM) to either nitrogen, oxygen or carbon atoms in DNA, RNA, proteins and small molecules. Its exact specificity is unknown; Localized in the cytoplasm; Specificity unclear; SAM-dependent methyltransferase 4944637 10976667 zobellia_4223 Zobellia galactanivorans SAM-dependent methyltransferase YP_004738637.1 4944035 D 63186 CDS YP_004738638.1 340620185 10976668 4944799..4945281 1 NC_015844.1 Transcriptional regulator belonging to the MarR family. Features a helix-turn-helix DNA binding motif. Localized in the cytoplasm.; Family membership; MarR-type transcriptional regulator 4945281 10976668 zobellia_4224 Zobellia galactanivorans MarR-type transcriptional regulator YP_004738638.1 4944799 D 63186 CDS YP_004738639.1 340620186 10976669 4945278..4945520 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4945520 10976669 zobellia_4225 Zobellia galactanivorans membrane protein YP_004738639.1 4945278 D 63186 CDS YP_004738640.1 340620187 10976670 4945870..4946433 1 NC_015844.1 The Crp/Fnr-type transcriptional regulators complexe with cyclic AMP and bind to operator sites near the promoter with a C-terminal HTH domain to regulate the transcription of several catabolite-sensitive operons; They predominantly act as transcription activators, but can also be important repressors, and respond to diverse intracellular and exogenous signals; Localized in the cytoplasm; Family membership; Crp/Fnr-type transcriptional regulator 4946433 10976670 zobellia_4226 Zobellia galactanivorans Crp/Fnr-type transcriptional regulator YP_004738640.1 4945870 D 63186 CDS YP_004738641.1 340620188 10976671 4946571..4946990 1 NC_015844.1 Ribonuclease UK114 is an endoribonuclease responsible for the inhibition of the translation by cleaving mRNA. Inhibits cell-free protein synthesis. Cleaves phosphodiester bonds only in single-stranded RNA. Localized in the cytoplasm.; High confidence in function and specificity; ribonuclease UK114 4946990 Hrsp12 10976671 Hrsp12 Zobellia galactanivorans ribonuclease UK114 YP_004738641.1 4946571 D 63186 CDS YP_004738642.1 340620189 10977993 complement(4947080..4947757) 1 NC_015844.1 This peptidase belongs to the family 56 of the cysteine peptidases. The catalytic diad is constituted by two consecutive conserved residues, Cys His. The enzyme forms a hexameric ring structure, and the active sites are proposed to be formed at the interfaces between three pairs of monomers. The peptidase monomer adopts a alpha/beta hydrolase fold. Localized in the cytoplasm.; Specificity unclear; intracellular peptidase 4947757 10977993 zobellia_4228 Zobellia galactanivorans intracellular peptidase YP_004738642.1 4947080 R 63186 CDS YP_004738643.1 340620190 10976672 complement(4947774..4948934) 1 NC_015844.1 Contains an Iron-containing alcohol dehydrogenase domain; Belongs to the iron-containing alcohol dehydrogenase family; Localized in the cytoplasm; Family membership; iron-containing alcohol dehydrogenase family protein 4948934 10976672 zobellia_4229 Zobellia galactanivorans iron-containing alcohol dehydrogenase family protein YP_004738643.1 4947774 R 63186 CDS YP_004738644.1 340620191 10976673 complement(4948964..4949959) 1 NC_015844.1 Contains an zinc-containing alcohol dehydrogenase superfamily domain; Belongs to the NADP-dependent oxidoreductase L4BD family; Possibly localized in the cytoplasmic membrane or in the cytoplasm; Family membership; NADP-dependent oxidoreductase 4949959 10976673 zobellia_4230 Zobellia galactanivorans NADP-dependent oxidoreductase YP_004738644.1 4948964 R 63186 CDS YP_004738645.1 340620192 10976675 complement(4949971..4950603) 1 NC_015844.1 Belongs to the nitroreductase family. This family include the oxygen-insensitive NAD(P)H nitroreductase (FMN-dependent nitroreductase) (Dihydropteridine reductase) (1.5.1.34) and NADH dehydrogenase (1.6.99.3); Members of this family use FMN as a cofactor; Localized in the cytoplasm; Family membership; NAD(P)H-flavin oxidoreductase 4950603 10976675 zobellia_4231 Zobellia galactanivorans NAD(P)H-flavin oxidoreductase YP_004738645.1 4949971 R 63186 CDS YP_004738646.1 340620193 10976676 complement(4950634..4951212) 1 NC_015844.1 Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership; TetR family transcriptional regulator 4951212 10976676 zobellia_4232 Zobellia galactanivorans TetR family transcriptional regulator YP_004738646.1 4950634 R 63186 CDS YP_004738647.1 340620194 10976677 4951412..4951891 1 NC_015844.1 Conserved protein belonging to the GAF family. GAF domains are present in phytochromes and cGMP-specific phosphodiesterases. Localized in the cytoplasm.; Family membership; hypothetical protein 4951891 10976677 zobellia_4233 Zobellia galactanivorans hypothetical protein YP_004738647.1 4951412 D 63186 CDS YP_004738648.1 340620195 10976678 complement(4951904..4952665) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 4952665 10976678 zobellia_4234 Zobellia galactanivorans periplasmic protein YP_004738648.1 4951904 R 63186 CDS YP_004738649.1 340620196 10976679 complement(4952789..4954249) 1 NC_015844.1 L-2,4-diaminobutyrate decarboxylase catalyzes the reaction : L-2,4-diaminobutanoate = propane-1,3-diamine + CO2. It is involved in 1,3-diaminopropane biosynthesis. This enzyme covalently binds the cofactor pyridoxal-phosphate (PLP) on a conserved lysine. Localized in the cytoplasm.; High confidence in function and specificity; L-2,4-diaminobutyrate decarboxylase 4954249 ddc 10976679 ddc Zobellia galactanivorans L-2,4-diaminobutyrate decarboxylase YP_004738649.1 4952789 R 63186 CDS YP_004738650.1 340620197 10977724 4954363..4955277 1 NC_015844.1 Transcriptional regulator belonging to the LysR family. Features a N-terminal helix-turn-helix DNA binding domain and a C-terminal LysR-like substrate binding domain. Localized in the cytoplasm.; Specificity unclear; LysR family transcriptional regulator 4955277 10977724 zobellia_4236 Zobellia galactanivorans LysR family transcriptional regulator YP_004738650.1 4954363 D 63186 CDS YP_004738651.1 340620198 10976680 4955490..4955975 1 NC_015844.1 Heat shock protein belonging to the HSP20 family. Acts as chaperone that can protect other proteins against heat-induced denaturation and aggregation. Hsp20 proteins seem to form large heterooligomeric aggregates. Localized in the cytoplasm.; Family membership; small heat shock protein 4955975 10976680 zobellia_4237 Zobellia galactanivorans small heat shock protein YP_004738651.1 4955490 D 63186 CDS YP_004738652.1 340620199 10976681 4956055..4956549 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 4956549 10976681 zobellia_4238 Zobellia galactanivorans hypothetical protein YP_004738652.1 4956055 D 63186 CDS YP_004738653.1 340620200 10976682 complement(4956644..4956787) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4956787 10976682 zobellia_4239 Zobellia galactanivorans hypothetical protein YP_004738653.1 4956644 R 63186 CDS YP_004738654.1 340620201 10976683 4956917..4957501 1 NC_015844.1 Peroxiredoxins are thiol peroxidase. They are involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. The peroxidase reaction comprises two steps centered around a redox- active cysteine called the peroxidatic cysteine. It attacks the peroxide substrate and is oxidized to S-hydroxycysteine (a sulfenic acid). The second step is the regeneration of cysteine from S-hydroxycysteine. This regeneration is due to thiol-containing reductants such as thioredoxin. Localized in the cytoplasm.; Specificity unclear; peroxiredoxin 4957501 10976683 zobellia_4240 Zobellia galactanivorans peroxiredoxin YP_004738654.1 4956917 D 63186 CDS YP_004738655.1 340620202 10976685 complement(4957517..4958410) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 4958410 10976685 zobellia_4241 Zobellia galactanivorans AraC family transcriptional regulator YP_004738655.1 4957517 R 63186 CDS YP_004738656.1 340620203 10976686 complement(4958531..4958641) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4958641 10976686 zobellia_4242 Zobellia galactanivorans hypothetical protein YP_004738656.1 4958531 R 63186 CDS YP_004738657.1 340620204 10976687 4958935..4960368 1 NC_015844.1 The beta-agarases hydrolyse the 1,4-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product; Contains a C-terminal domain of unknown function; Belongs to the family 16 of glycoside hydrolases (GH16); Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space and possibly secreted in the extracellular medium; High confidence in function and specificity; beta-agarase D 4960368 agaD 10976687 agaD Zobellia galactanivorans beta-agarase D YP_004738657.1 4958935 D 63186 CDS YP_004738658.1 340620205 10977486 4960769..4961068 1 NC_015844.1 Protein Belongs to the antibiotic biosynthesis monooxygenase (ABM) family; Localized in the cytoplasm; Family membership; antibiotic biosynthesis monooxygenase family protein 4961068 10977486 zobellia_4244 Zobellia galactanivorans antibiotic biosynthesis monooxygenase family protein YP_004738658.1 4960769 D 63186 CDS YP_004738659.1 340620206 10976688 4961130..4961603 1 NC_015844.1 DspA protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction; Forms a homododecamer and the 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited; Localized in the cytoplasm; High confidence in function and specificity; DNA protection during starvation protein 4961603 dpsA3 10976688 dpsA3 Zobellia galactanivorans DNA protection during starvation protein YP_004738659.1 4961130 D 63186 CDS YP_004738660.1 340620207 10977764 4961626..4962570 1 NC_015844.1 Oxydoreductase NADPH dependent; Belongs to the aldo/keto reductase 2 family; Localized in the cytoplasm; Family membership; aldo/keto reductase 4962570 10977764 zobellia_4246 Zobellia galactanivorans aldo/keto reductase YP_004738660.1 4961626 D 63186 CDS YP_004738661.1 340620208 10976689 4962589..4963383 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Possible signal peptide cleaved between the residues 24 and 25; Putatively localized in the periplasmic space; Family membership; short-chain dehydrogenase/reductase 4963383 10976689 zobellia_4247 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004738661.1 4962589 D 63186 CDS YP_004738662.1 340620209 10976690 4963465..4964100 1 NC_015844.1 Alpha-ketoglutarate-dependent dioxygenase repairs alkylated DNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Has a strong preference for single-stranded DNA. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Localized in the cytoplasm.; High confidence in function and specificity; alpha-ketoglutarate-dependent dioxygenase 4964100 alkB2 10976690 alkB2 Zobellia galactanivorans alpha-ketoglutarate-dependent dioxygenase YP_004738662.1 4963465 D 63186 CDS YP_004738663.1 340620210 10977506 4964308..4964967 1 NC_015844.1 Also called oxygen-insensitive NAD(P)H nitroreductase this enzyme reduces a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents, two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide); Uses the FMN as cofactor; Belongs to the nitroreductase family; Localized in the cytoplasm; High confidence in function and specificity; 6,7-dihydropteridine reductase 4964967 nfnB2 10977506 nfnB2 Zobellia galactanivorans 6,7-dihydropteridine reductase YP_004738663.1 4964308 D 63186 CDS YP_004738664.1 340620211 10978246 4964992..4965999 1 NC_015844.1 The NADP-dependent quinone oxidoreductase catalyzes the one-electron reduction of certain quinones; orthoquinones are the best substrates. It is an enzyme found in bacteria, in yeast and in mammals where, in some species such as rodents, it has been recruited as an eye lens protein and is known as zeta-crystallin; Belongs to the zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily; Localized in the cytoplasm; High confidence in function and specificity; quinone oxidoreductase 4965999 qorA2 10978246 qorA2 Zobellia galactanivorans quinone oxidoreductase YP_004738664.1 4964992 D 63186 CDS YP_004738665.1 340620212 10978427 4966030..4966497 1 NC_015844.1 Contains a C-terminal Cupin domain; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; hypothetical protein 4966497 10978427 zobellia_4251 Zobellia galactanivorans hypothetical protein YP_004738665.1 4966030 D 63186 CDS YP_004738666.1 340620213 10976692 4966499..4967605 1 NC_015844.1 Signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; hypothetical protein 4967605 10976692 zobellia_4252 Zobellia galactanivorans hypothetical protein YP_004738666.1 4966499 D 63186 CDS YP_004738667.1 340620214 10976693 4967981..4969534 1 NC_015844.1 Helicases are involved in unwinding nucleic acids; Contains a N-terminal ResIII domain or DEAD domain and a C-terminal helicase domain; Belongs to the superfamily II of helicases; Localized in the cytoplasm; Family membership; ATP-dependent helicase 4969534 10976693 zobellia_4253 Zobellia galactanivorans ATP-dependent helicase YP_004738667.1 4967981 D 63186 CDS YP_004738668.1 340620215 10976694 4969601..4969693 1 NC_015844.1 Hypothetical protein; hypothetical protein 4969693 10976694 zobellia_4254 Zobellia galactanivorans hypothetical protein YP_004738668.1 4969601 D 63186 CDS YP_004738669.1 340620216 10976695 4969774..4970379 1 NC_015844.1 K+/H+ antiporter, ancillary protein KefF, also called Glutathione-regulated potassium-efflux system ancillary protein is required for full activity of KefC. This ancillary protein stimulates transport activity of KefC about 10-fold. It is unlikely that kefF has oxidoreductase activity, it has probably evolved from its function as oxidoreductase to be regulator of kefC; Belongs to the NAD(P)H dehydrogenase (quinone) family; Localized in the cytoplasm; High confidence in function and specificity; K+/H+ antiporter, ancillary protein KefF 4970379 kefF 10976695 kefF Zobellia galactanivorans K+/H+ antiporter, ancillary protein KefF YP_004738669.1 4969774 D 63186 CDS YP_004738670.1 340620217 10978067 4970376..4972262 1 NC_015844.1 The K(+)/H(+) antiporter KefC is a Glutathione-regulated potassium-efflux system protein responsible for glutathione-gated K+ efflux. Activation of KefC K+ efflux system only occurs in the presence of glutathione and a reactive electrophile such as methylglyoxal or N-ethylmaleimide. KefC is important for cell survival during exposure to toxic metabolites, possibly because they can release K+, allowing H+ uptake. H+ uptake (acidification of the cytoplasm) accompanying or following K+ efflux may serve as a further protective mechanism against electrophile toxicity; Contains 12 transmembrane segments and a RCK N-terminal domain; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter family; Localized in the cytoplasmic membrane; High confidence in function and specificity; K(+)/H(+) antiporter 4972262 kefC 10978067 kefC Zobellia galactanivorans K(+)/H(+) antiporter YP_004738670.1 4970376 D 63186 CDS YP_004738671.1 340620218 10978066 4972273..4972599 1 NC_015844.1 Protein that consists of an TfoX module found in the N-terminal part of the tfoX gene product required for DNA transformation; Localized in the cytoplasm; hypothetical protein 4972599 10978066 zobellia_4257 Zobellia galactanivorans hypothetical protein YP_004738671.1 4972273 D 63186 CDS YP_004738672.1 340620219 10976696 complement(4972628..4973359) 1 NC_015844.1 The generic name 'NUDIX hydrolases' corresponds to pyrophosphatases cleaving a NUcleoside DIphosphate linked to some other moiety X. These enzymes hydrolyze diverse nucleoside diphosphate derivatives (including ADP-ribose, GDP- mannose, TDP-glucose, NADH, UDP-sugars, dNTP and NTP). Localized in the cytoplasm.; Specificity unclear; NUDIX hydrolase 4973359 10976696 zobellia_4258 Zobellia galactanivorans NUDIX hydrolase YP_004738672.1 4972628 R 63186 CDS YP_004738673.1 340620220 10976697 4973710..4974501 1 NC_015844.1 Probably localized in the cytoplasm; hypothetical protein 4974501 10976697 zobellia_4259 Zobellia galactanivorans hypothetical protein YP_004738673.1 4973710 D 63186 CDS YP_004738674.1 340620221 10976698 4974631..4975692 1 NC_015844.1 RbsB is the D-ribose-binding protein involved in the high-affinity D-ribose membrane transport system; Belongs to the bacterial solute-binding protein 2 family; Seems to have a uncleavable signal sequence; Localized in the cytoplasmic membrane and exposed in the periplasmic space; High confidence in function and specificity; ribose ABC transporter periplasmic 4975692 rbsB 10976698 rbsB Zobellia galactanivorans ribose ABC transporter periplasmic YP_004738674.1 4974631 D 63186 CDS YP_004738675.1 340620222 10978435 4975702..4977228 1 NC_015844.1 Part of the ABC transporter complex RbsABCD involved in D-ribose import. RbsA is Responsible for energy coupling to the transport system; The complex is composed of two ATP-binding proteins , two transmembrane proteins (rbsC and rbsD) and a solute-binding protein (rbsB); Contains 2 ABC transporter domains; Belongs to the ABC transporter family, ribose importer subfamily; Localized in the cytoplasmic membrane as a peripheral membrane protein; High confidence in function and specificity; ribose ABC transporter ATPase 4977228 rbsA 10978435 rbsA Zobellia galactanivorans ribose ABC transporter ATPase YP_004738675.1 4975702 D 63186 CDS YP_004738676.1 340620223 10978434 4977245..4978213 1 NC_015844.1 Part of the binding-protein-dependent ABC transporter system for D-ribose. Probably responsible for the translocation of the substrate across the membrane; Contains seven transmembrane segments; Belongs to the binding-protein-dependent transport system permease family; Localized in the cytoplasmic membrane; High confidence in function and specificity; ribose ABC transporter permease 4978213 rbsC 10978434 rbsC Zobellia galactanivorans ribose ABC transporter permease YP_004738676.1 4977245 D 63186 CDS YP_004738677.1 340620224 10978436 4978227..4979723 1 NC_015844.1 D-mannonate oxidoreductase or Fructuronate reductase catalyzes the NAD-dependent reduction of fructuronate into mannonate; Belongs to the Long-chain mannitol dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity; d-mannonate oxidoreductase 4979723 uxuB 10978436 uxuB Zobellia galactanivorans d-mannonate oxidoreductase YP_004738677.1 4978227 D 63186 CDS YP_004738678.1 340620225 10978741 4979724..4980611 1 NC_015844.1 Fructokinase catalyzes the transfer of a phosphate group from ATP to convert the fructose to fructose-6-phosphate, which is an entry point into glycolysis (Embden-Meyerhof pathway) via conversion into glucose-6-phosphate; Belongs to the carbohydrate kinase PfkB superfamily, bacterial fructokinase family; Localized in the cytoplasm; Family membership; fructokinase 4980611 scrK2 10978741 scrK2 Zobellia galactanivorans fructokinase YP_004738678.1 4979724 D 63186 CDS YP_004738679.1 340620226 10978568 complement(4980692..4982167) 1 NC_015844.1 The Iota-carrageenases hydrolyse the 1,4-beta-D-galactosidic linkages in the iota-carrgeenan giving the tetramer as the predominant product; Belongs to the family 82 of glycoside hydrolases (GH82); Signal peptide of lipoprotein cleaved between the residues 19 and 20; Localized in the outer membrane and possibly secreted in the outside medium; High confidence in function and specificity; iota-carrageenase 4982167 cgiA1 10978568 cgiA1 Zobellia galactanivorans iota-carrageenase YP_004738679.1 4980692 R 63186 CDS YP_004738680.1 340620227 10977645 complement(4982249..4982374) 1 NC_015844.1 Hypothetical protein; hypothetical protein 4982374 10977645 zobellia_4266 Zobellia galactanivorans hypothetical protein YP_004738680.1 4982249 R 63186 CDS YP_004738681.1 340620228 10976700 4982742..4983728 1 NC_015844.1 The beta-agarases Hydrolyse the 1,4-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product; Belongs to the family 16 of glycoside hydrolases (GH16); Lipoprotein-type signal peptide cleaved between the residues 17 and 18; Localized in the outer membrane and possibly secreted in the outside medium; High confidence in function and specificity; beta-agarase C 4983728 agaC 10976700 agaC Zobellia galactanivorans beta-agarase C YP_004738681.1 4982742 D 63186 CDS YP_004738682.1 340620229 10977485 complement(4983793..4985184) 1 NC_015844.1 Protein probably adopting a parallel beta-helix fold and acting with polysaccharide as substrates; Contains a putative lipoprotein signal peptide cleaved between the residues 18 and 19; Possibly localized in the outer membrane; Conserved hypothetical protein; Parallel beta-helix fold protein 4985184 10977485 zobellia_4268 Zobellia galactanivorans Parallel beta-helix fold protein YP_004738682.1 4983793 R 63186 CDS YP_004738683.1 340620230 10976701 4985446..4986171 1 NC_015844.1 This enzyme belongs to the acid phosphatase/vanadium-dependent haloperoxidase family; Seems to have an uncleavable signal peptide; Possibly localized in the cytoplasmic membrane; Family membership; acid phosphatase/vanadium-dependent haloperoxidase family protein 4986171 10976701 zobellia_4269 Zobellia galactanivorans acid phosphatase/vanadium-dependent haloperoxidase family protein YP_004738683.1 4985446 D 63186 CDS YP_004738684.1 340620231 10976702 4986325..4986687 1 NC_015844.1 The transcriptional regulators with the marR-type HTH domain control a variety of biological functions, including resistance to multiple antibiotics, household disinfectants, organic solvents, oxidative stress agents. Many of the marR-like regulators respond to aromatic compounds; Contains a DNA-binding, winged helix-turn-helix (wHTH) domain; Localized in the cytoplasm; Family membership; MarR-type transcriptional regulator 4986687 10976702 zobellia_4270 Zobellia galactanivorans MarR-type transcriptional regulator YP_004738684.1 4986325 D 63186 CDS YP_004738685.1 340620232 10976704 4986688..4987635 1 NC_015844.1 The Ornithine cyclodeaminase catalyses the deamination of ornithine to proline; The reaction uses the NAD as cofactor and is stimulated by the presence of ADP or ATP and is inhibited by O(2); Belongs to the mu- crystallin protein family; Localized in the cytoplasm; High confidence in function and specificity; ornithine cyclodeaminase 4987635 arcB 10976704 arcB Zobellia galactanivorans ornithine cyclodeaminase YP_004738685.1 4986688 D 63186 CDS YP_004738686.1 340620233 10977531 4987840..4989336 1 NC_015844.1 Lipoprotein belonging to the spore coat protein H family; Signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; hypothetical protein 4989336 10977531 zobellia_4272 Zobellia galactanivorans hypothetical protein YP_004738686.1 4987840 D 63186 CDS YP_004738687.1 340620234 10976705 complement(4989428..4989925) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 4989925 10976705 zobellia_4273 Zobellia galactanivorans hypothetical protein YP_004738687.1 4989428 R 63186 CDS YP_004738688.1 340620235 10976706 4990200..4991531 1 NC_015844.1 The outer membrane efflux proteins (OEP) are composed of two repeats of OEP domain to form a trimeric channel continuous, solvent-accessible conduit that spans both the outer membrane and periplasmic space; May be specialized for the signal peptide independent extracellular secretion of a variety of substrates in Gram-negative bacteria; Signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Belongs to the type I secretion system; Family membership; outer membrane efflux protein 4991531 10976706 zobellia_4274 Zobellia galactanivorans outer membrane efflux protein YP_004738688.1 4990200 D 63186 CDS YP_004738689.1 340620236 10976707 4991537..4992754 1 NC_015844.1 The membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics (as macrolides), solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmique membrane by a N-terminal transmembrane region; Belongs to the type I secretion system; Family membership; Macrolide-specific membrane fusion protein 4992754 macA 10976707 macA Zobellia galactanivorans Macrolide-specific membrane fusion protein YP_004738689.1 4991537 D 63186 CDS YP_004738690.1 340620237 10978116 4992764..4993507 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Putatively involved in the macrolides resistance; Localized in the cytoplasm near of the cytoplasmic membrane by association with the ABC transporter permease component; Family membership; Macrolide-specific ABC transporter ATPase 4993507 10978116 zobellia_4276 Zobellia galactanivorans Macrolide-specific ABC transporter ATPase YP_004738690.1 4992764 D 63186 CDS YP_004738691.1 340620238 10976708 4993510..4994730 1 NC_015844.1 ABC (ATP-binding cassette) membrane domain possibly involved in the macrolides resistance; Contains four transmembrane segments; Belongs to the ABC transporter family; Localized in the cytoplasmic membrane; Family membership; Macrolide-specific ABC transporter permease 4994730 macB 10976708 macB Zobellia galactanivorans Macrolide-specific ABC transporter permease YP_004738691.1 4993510 D 63186 CDS YP_004738692.1 340620239 10978117 4994738..4995775 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains four N-terminal transmembrane segments; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 4995775 10978117 zobellia_4278 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738692.1 4994738 D 63186 CDS YP_004738693.1 340620240 10976709 4995945..4997744 1 NC_015844.1 The ABC-1 type transporters have their ABC membrane domain and their ABC ATPase domain fused in the same protein. They are involved in the efflux of compounds across the biological membranes or in targeting of membrane components; Contains five N-terminal transmembrane segments (ABC membrane) that form a pore in the cytoplasmic membrane an a C-terminal ATP-binding domain (ABC ATPase) responsible for energy generation; Belongs to the ABC-1 type transporter permease/ATP-binding family, lipid exporter subfamily (msbA); Family membership; ABC-1 type exporter ATP-binding/permease protein 4997744 10976709 zobellia_4279 Zobellia galactanivorans ABC-1 type exporter ATP-binding/permease protein YP_004738693.1 4995945 D 63186 CDS YP_004738694.1 340620241 10976710 4997794..4999116 1 NC_015844.1 Contains two transmembrane segments in the N-terminal part of protein; Signal peptide cleaved between the residues 19 and 20; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 4999116 10976710 zobellia_4280 Zobellia galactanivorans membrane protein YP_004738694.1 4997794 D 63186 CDS YP_004738695.1 340620242 10976712 4999113..4999712 1 NC_015844.1 Protein possibly involved in the Phospholipid binding; Belongs to the phosphatidylethanolamine-binding protein (PEBP) family; Lipoprotein-type signal peptide cleaved between the residues 17 and 18; Localized in the outer membrane; Function unclear; phosphatidylethanolamine-binding protein 4999712 10976712 zobellia_4281 Zobellia galactanivorans phosphatidylethanolamine-binding protein YP_004738695.1 4999113 D 63186 CDS YP_004738696.1 340620243 10976713 4999730..5000737 1 NC_015844.1 Putative lipoprotein signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; Conserved hypothetical protein; membrane protein 5000737 10976713 zobellia_4282 Zobellia galactanivorans membrane protein YP_004738696.1 4999730 D 63186 CDS YP_004738697.1 340620244 10976714 5000774..5001508 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, that acts as transcriptional regulator; Family membership; two-component system-response regulator 5001508 10976714 zobellia_4283 Zobellia galactanivorans two-component system-response regulator YP_004738697.1 5000774 D 63186 CDS YP_004738698.1 340620245 10976715 5001651..5002100 1 NC_015844.1 Hypothetical Co-chaperone that could be part of a chaperone (protein folding) system; Contains a N-terminal 'J' domain; Belongs to the J-protein family, type 3 subgroup; Localized in the cytoplasm; Function unclear; putative co-chaperone 5002100 10976715 zobellia_4284 Zobellia galactanivorans putative co-chaperone YP_004738698.1 5001651 D 63186 CDS YP_004738699.1 340620246 10976716 5002226..5003557 1 NC_015844.1 Protein that could be involved in ATP-dependent RNA unwinding in a variety of cellular processes, including ribosome assembly, protein synthesis, and RNA degradation; Contains a DEAD box; Belongs to the helicases superfamily II, DEAD/DEAH box RNA helicase family, DEAD box subfamily; Localized in the cytoplasm; Family membership; DEAD/DEAH RNA helicase 5003557 10976716 zobellia_4285 Zobellia galactanivorans DEAD/DEAH RNA helicase YP_004738699.1 5002226 D 63186 CDS YP_004738700.1 340620247 10976717 5003561..5004874 1 NC_015844.1 RNA helicase DbpA Has a helix-destabilizing activity, not coupled to the ATPase activity. Can unwind the 23S rRNA as well as 16S rRNA. Exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA. Could play a major role in the assembly process of the active center of 50S ribosomal subunits; Contains a C-terminal DbpA RNA binding domain specific for hairpin 92 of 23S rRNA; Belongs to the helicases superfamily II, DEAD/DEAH box RNA helicase family, DEAD box subfamily; Localized in the cytoplasm; High confidence in function and specificity; RNA helicase DbpA 5004874 dbpA 10976717 dbpA Zobellia galactanivorans RNA helicase DbpA YP_004738700.1 5003561 D 63186 CDS YP_004738701.1 340620248 10977722 5005272..5005463 1 NC_015844.1 Cold shock proteins (CSPs) help the cell to survive in temperatures lower than optimum growth temperature. CSPs may act as RNA chaperones by destabilizing RNA secondary structures, regulating ribosomal translation, rate of mRNA degradation and termination of transcription; Contains a 'cold-shock domain' (CSD) involved in the single-strand nucleic-acid binding; Localized in the cytoplasm; High confidence in function and specificity; cold shock protein 5005463 cspA5 10977722 cspA5 Zobellia galactanivorans cold shock protein YP_004738701.1 5005272 D 63186 CDS YP_004738702.1 340620249 10977689 5005766..5006065 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; localized in the outer membrane; Hypothetical protein; hypothetical protein 5006065 10977689 zobellia_4288 Zobellia galactanivorans hypothetical protein YP_004738702.1 5005766 D 63186 CDS YP_004738703.1 340620250 10976718 5006305..5006892 1 NC_015844.1 Protein that corresponds to a conserved domain in several bacterial protein; Signal peptide cleaved between the residues 24 and 25; Localized in the outer membrane; Conserved hypothetical protein; membrane protein 5006892 10976718 zobellia_4289 Zobellia galactanivorans membrane protein YP_004738703.1 5006305 D 63186 CDS YP_004738704.1 340620251 10976719 5007143..5008690 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 5008690 10976719 zobellia_4290 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004738704.1 5007143 D 63186 CDS YP_004738705.1 340620252 10976721 complement(5008706..5009317) 1 NC_015844.1 Protein that could be involved in ATP-dependent RNA unwinding in a variety of cellular processes, including ribosome assembly, protein synthesis, and RNA degradation; Contains a DEAD box; Belongs to the helicases superfamily II, DEAD/DEAH box RNA helicase family; Localized in the cytoplasm; Family membership; DEAD/DEAH RNA helicase 5009317 10976721 zobellia_4291 Zobellia galactanivorans DEAD/DEAH RNA helicase YP_004738705.1 5008706 R 63186 CDS YP_004738706.1 340620253 10976722 5009735..5011384 1 NC_015844.1 Serine peptidase belonging to the family S12, which includes D-Ala-D-Ala carboxypeptidase B and aminopeptidase DmpB. The active site residues Ser and Lys form the catalytic dyad and are found in the motif Ser-Xaa-Thr-Lys. Signal peptide cleaved between the residues 22 and 23. Localized in the periplasmic space.; Specificity unclear; serine peptidase 5011384 10976722 zobellia_4292 Zobellia galactanivorans serine peptidase YP_004738706.1 5009735 D 63186 CDS YP_004738707.1 340620254 10976723 5011543..5012523 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 5012523 10976723 zobellia_4293 Zobellia galactanivorans hypothetical protein YP_004738707.1 5011543 D 63186 CDS YP_004738708.1 340620255 10976724 5012550..5012921 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 5012921 10976724 zobellia_4294 Zobellia galactanivorans hypothetical protein YP_004738708.1 5012550 D 63186 CDS YP_004738709.1 340620256 10976725 5013376..5014305 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two transmembrane segments; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 5014305 10976725 zobellia_4295 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004738709.1 5013376 D 63186 CDS YP_004738710.1 340620257 10976726 complement(5014518..5014613) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5014613 10976726 zobellia_4296 Zobellia galactanivorans hypothetical protein YP_004738710.1 5014518 R 63186 CDS YP_004738711.1 340620258 10976727 5014632..5016368 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5016368 10976727 zobellia_4297 Zobellia galactanivorans hypothetical protein YP_004738711.1 5014632 D 63186 CDS YP_004738712.1 340620259 10976728 5016379..5016744 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5016744 10976728 zobellia_4298 Zobellia galactanivorans hypothetical protein YP_004738712.1 5016379 D 63186 CDS YP_004738713.1 340620260 10976729 complement(5016765..5017664) 1 NC_015844.1 Conserved membrane protein containing two DUF family domains. Features ten transmembrane helices. Localized in the cytoplasmic membrane.; Family membership; hypothetical protein 5017664 10976729 zobellia_4299 Zobellia galactanivorans hypothetical protein YP_004738713.1 5016765 R 63186 CDS YP_004738714.1 340620261 10976730 5017879..5019099 1 NC_015844.1 Conserved phospholipase belonging to the patatin family. Displays a C-terminal domain of unknown function.; Family membership; Patatin-like phospholipase 5019099 10976730 zobellia_4300 Zobellia galactanivorans Patatin-like phospholipase YP_004738714.1 5017879 D 63186 CDS YP_004738715.1 340620262 10976732 5019141..5020334 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 5020334 10976732 zobellia_4301 Zobellia galactanivorans hypothetical protein YP_004738715.1 5019141 D 63186 CDS YP_004738716.1 340620263 10976733 5020327..5022111 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 5022111 10976733 zobellia_4302 Zobellia galactanivorans hypothetical protein YP_004738716.1 5020327 D 63186 CDS YP_004738717.1 340620264 10976734 5022282..5023550 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 5023550 10976734 zobellia_4303 Zobellia galactanivorans hypothetical protein YP_004738717.1 5022282 D 63186 CDS YP_004738718.1 340620266 10976735 complement(5023558..5024250) 1 NC_015844.1 Iodotyrosine dehalogenase catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Uses FMN and NADPH as cofactors. Belongs to the nitroreductase family. Localized in the cytoplasm.; Hypothetical protein; iodotyrosine dehalogenase 5024250 iyd 10976735 iyd Zobellia galactanivorans iodotyrosine dehalogenase YP_004738718.1 5023558 R 63186 CDS YP_004738719.1 340620265 10978046 5024215..5024418 1 NC_015844.1 Hypothetical protein; hypothetical protein 5024418 10978046 zobellia_4304 Zobellia galactanivorans hypothetical protein YP_004738719.1 5024215 D 63186 CDS YP_004738720.1 340620267 10976736 complement(5024407..5025039) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 5025039 10976736 zobellia_4306 Zobellia galactanivorans hypothetical protein YP_004738720.1 5024407 R 63186 CDS YP_004738721.1 340620268 10976737 complement(5025060..5025653) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; localized in the outer membrane; Conserved hypothetical protein; lipoprotein 5025653 10976737 zobellia_4307 Zobellia galactanivorans lipoprotein YP_004738721.1 5025060 R 63186 CDS YP_004738722.1 340620269 10976738 5026013..5026321 1 NC_015844.1 Hypothetical protein; hypothetical protein 5026321 10976738 zobellia_4308 Zobellia galactanivorans hypothetical protein YP_004738722.1 5026013 D 63186 CDS YP_004738723.1 340620270 10976739 5026332..5026592 1 NC_015844.1 Hypothetical protein; hypothetical protein 5026592 10976739 zobellia_4309 Zobellia galactanivorans hypothetical protein YP_004738723.1 5026332 D 63186 CDS YP_004738724.1 340620271 10976740 5026881..5028362 1 NC_015844.1 Contains a signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5028362 10976740 zobellia_4310 Zobellia galactanivorans periplasmic protein YP_004738724.1 5026881 D 63186 CDS YP_004738725.1 340620272 10976742 complement(5028468..5030696) 1 NC_015844.1 Nitric oxide reductase (NOR) is a component of the anaerobic respiratory chain that transforms nitrate to dinitrogen (denitrification). NorBC is a modular protein consisting of a N-terminal domain distantly related to NorC and a C-terminal domain Binds a heme as cofactor; Contains fourteen transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; nitric oxide reductase 5030696 norBC 10976742 norBC Zobellia galactanivorans nitric oxide reductase YP_004738725.1 5028468 R 63186 CDS YP_004738726.1 340620273 10978256 complement(5030707..5031048) 1 NC_015844.1 Protein displaying the conserved barrel domain of the 'cupin' superfamily; Localized in the cytoplasm; hypothetical protein 5031048 10978256 zobellia_4312 Zobellia galactanivorans hypothetical protein YP_004738726.1 5030707 R 63186 CDS YP_004738727.1 340620274 10976743 5031686..5032246 1 NC_015844.1 Signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5032246 10976743 zobellia_4313 Zobellia galactanivorans periplasmic protein YP_004738727.1 5031686 D 63186 CDS YP_004738728.1 340620275 10976744 complement(5032227..5032328) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5032328 10976744 zobellia_4314 Zobellia galactanivorans hypothetical protein YP_004738728.1 5032227 R 63186 CDS YP_004738729.1 340620276 10976745 5032370..5032468 1 NC_015844.1 Hypothetical protein; hypothetical protein 5032468 10976745 zobellia_4315 Zobellia galactanivorans hypothetical protein YP_004738729.1 5032370 D 63186 CDS YP_004738730.1 340620277 10976746 5032455..5034011 1 NC_015844.1 Displays distant similarity with the Patatin-like phospholipases; Contains two central transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5034011 10976746 zobellia_4316 Zobellia galactanivorans membrane protein YP_004738730.1 5032455 D 63186 CDS YP_004738731.1 340620278 10976747 5034008..5034541 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5034541 10976747 zobellia_4317 Zobellia galactanivorans hypothetical protein YP_004738731.1 5034008 D 63186 CDS YP_004738732.1 340620279 10976748 complement(5034613..5035173) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5035173 10976748 zobellia_4318 Zobellia galactanivorans hypothetical protein YP_004738732.1 5034613 R 63186 CDS YP_004738733.1 340620280 10976749 complement(5035427..5036290) 1 NC_015844.1 Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5036290 10976749 zobellia_4319 Zobellia galactanivorans periplasmic protein YP_004738733.1 5035427 R 63186 CDS YP_004738734.1 340620281 10976750 5036373..5036561 1 NC_015844.1 Hypothetical protein; hypothetical protein 5036561 10976750 zobellia_4320 Zobellia galactanivorans hypothetical protein YP_004738734.1 5036373 D 63186 CDS YP_004738735.1 340620282 10976752 complement(5036603..5037904) 1 NC_015844.1 Protein that could be involved in pH homeostasis and sodium extrusion; Belongs to the nhaC Na(+)/H(+) antiporter family; Contains eleven transmembrane helices; Localized in the cytoplasmic membrane; Family membership; Na+/H+ antiporter 5037904 10976752 zobellia_4321 Zobellia galactanivorans Na+/H+ antiporter YP_004738735.1 5036603 R 63186 CDS YP_004738736.1 340620283 10976753 5037937..5038182 1 NC_015844.1 Hypothetical protein; hypothetical protein 5038182 10976753 zobellia_4322 Zobellia galactanivorans hypothetical protein YP_004738736.1 5037937 D 63186 CDS YP_004738737.1 340620284 10976754 complement(5038371..5038511) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5038511 10976754 zobellia_4323 Zobellia galactanivorans hypothetical protein YP_004738737.1 5038371 R 63186 CDS YP_004738738.1 340620285 10976755 5038562..5040148 1 NC_015844.1 This protein displays three KWG repeats (residues 175-189, 258-275 and 307-323); Signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5040148 10976755 zobellia_4324 Zobellia galactanivorans periplasmic protein YP_004738738.1 5038562 D 63186 CDS YP_004738739.1 340620286 10976756 5040338..5041360 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; localized in the outer membrane; Hypothetical protein; hypothetical protein 5041360 10976756 zobellia_4325 Zobellia galactanivorans hypothetical protein YP_004738739.1 5040338 D 63186 CDS YP_004738740.1 340620287 10976757 5041738..5043846 1 NC_015844.1 Conserved protein adopting a parallel beta-helix fold. Features a signal peptide cleaved between the residues 27 and 28. Localized in the periplasm.; Conserved hypothetical protein; beta-helix fold protein 5043846 10976757 zobellia_4326 Zobellia galactanivorans beta-helix fold protein YP_004738740.1 5041738 D 63186 CDS YP_004738741.1 340620288 10976758 5043878..5045050 1 NC_015844.1 Alginate lyase catalyzes the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends. It belongs to the family 7 of the polysaccharide lyases. Display also a C-terminal conserved domain of unknown function. Features an uncleaved signal peptide., Features a signal peptide cleaved between residues 24 and 25. Localized in the periplasm.; High confidence in function and specificity; alginate lyase 5045050 alyA7 10976758 alyA7 Zobellia galactanivorans alginate lyase YP_004738741.1 5043878 D 63186 CDS YP_004738742.1 340620289 10977517 complement(5045140..5046480) 1 NC_015844.1 Putatif ABC-2 type (ATP-binding cassette) transporter, membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 5046480 10977517 zobellia_4328 Zobellia galactanivorans ABC transporter permease YP_004738742.1 5045140 R 63186 CDS YP_004738743.1 340620290 10976759 complement(5046481..5047920) 1 NC_015844.1 Putatif ABC-2 type (ATP-binding cassette) transporter, membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 5047920 10976759 zobellia_4329 Zobellia galactanivorans ABC transporter permease YP_004738743.1 5046481 R 63186 CDS YP_004738744.1 340620291 10976760 complement(5047923..5050430) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-101) and the Plug module (136-233) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership; TonB-dependent Receptor 5050430 10976760 zobellia_4330 Zobellia galactanivorans TonB-dependent Receptor YP_004738744.1 5047923 R 63186 CDS YP_004738745.1 340620292 10976762 complement(5050436..5051206) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; Family membership; ABC transporter ATPase 5051206 10976762 zobellia_4331 Zobellia galactanivorans ABC transporter ATPase YP_004738745.1 5050436 R 63186 CDS YP_004738746.1 340620293 10976763 complement(5051388..5051687) 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 5051687 10976763 zobellia_4332 Zobellia galactanivorans hypothetical protein YP_004738746.1 5051388 R 63186 CDS YP_004738747.1 340620294 10976764 5051998..5052738 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 5052738 10976764 zobellia_4333 Zobellia galactanivorans hypothetical protein YP_004738747.1 5051998 D 63186 CDS YP_004738748.1 340620295 10976765 complement(5052974..5053096) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5053096 10976765 zobellia_4334 Zobellia galactanivorans hypothetical protein YP_004738748.1 5052974 R 63186 CDS YP_004738749.1 340620296 10976766 complement(5053139..5055229) 1 NC_015844.1 Modular protein containing two N-terminal AraC-type HTH DNA-binding domains involved in the binding of the protein to the operator sequences in the DNA followed by two C-terminal Tetratricopeptide repeats. AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons. TPR repeats mediate proteinprotein interactions and the assembly of multiprotein complexes. A single TPR contains two antiparallel α helices which pack into an open structure such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that might accommodate the complementary region of a target protein. Localized in the cytoplasm.; Function unclear; AraC family transcriptional regulator 5055229 10976766 zobellia_4335 Zobellia galactanivorans AraC family transcriptional regulator YP_004738749.1 5053139 R 63186 CDS YP_004738750.1 340620297 10976767 5055450..5056037 1 NC_015844.1 Conserved protein containing three ankyrin repeats, one of the most common protein-protein interaction motifs in nature; Signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Function unclear; ankyrin repeat-containing protein 5056037 10976767 zobellia_4336 Zobellia galactanivorans ankyrin repeat-containing protein YP_004738750.1 5055450 D 63186 CDS YP_004738751.1 340620298 10976768 5056065..5057165 1 NC_015844.1 Conserved protein belonging to the acyltransferase family. Its exact function is unclear. Features ten transmembrane helices. Localized in the cytoplasmic membrane.; Family membership; acyltransferase family protein 5057165 10976768 zobellia_4337 Zobellia galactanivorans acyltransferase family protein YP_004738751.1 5056065 D 63186 CDS YP_004738752.1 340620299 10976769 5057308..5057886 1 NC_015844.1 Protein phosphatase with activity toward tyrosine-protein phosphate as well as toward serine-protein phosphate. Features a signal peptide cleaved between the residues 23 and 24. Localized in the periplasm.; Specificity unclear; Dual specificity protein phosphatase 5057886 10976769 zobellia_4338 Zobellia galactanivorans Dual specificity protein phosphatase YP_004738752.1 5057308 D 63186 CDS YP_004738753.1 340620300 10976770 5058014..5059012 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 5059012 10976770 zobellia_4339 Zobellia galactanivorans hypothetical protein YP_004738753.1 5058014 D 63186 CDS YP_004738754.1 340620301 10976771 5059117..5059884 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5059884 10976771 zobellia_4340 Zobellia galactanivorans periplasmic protein YP_004738754.1 5059117 D 63186 CDS YP_004738755.1 340620302 10976773 complement(5059903..5061024) 1 NC_015844.1 ABC-2 Type (ATP-binding cassette) transporter, membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Specificity unclear; ABC transporter permease 5061024 ybhR 10976773 ybhR Zobellia galactanivorans ABC transporter permease YP_004738755.1 5059903 R 63186 CDS YP_004738756.1 340620303 10978779 complement(5061024..5062130) 1 NC_015844.1 ABC-2 Type (ATP-binding cassette) transporter, membrane domain; ABC-2 type transporters are responsible for extrusion of a variety of compounds across biological membranes; Contains six transmembrane segments; The proteins form homo- or hetero-oligomeric channels, allowing ATP-mediated transport; Localized in the cytoplasmic membrane; Specificity unclear; ABC transporter permease 5062130 ybhS 10978779 ybhS Zobellia galactanivorans ABC transporter permease YP_004738756.1 5061024 R 63186 CDS YP_004738757.1 340620304 10978780 complement(5062127..5062855) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; Family membership; ABC transporter ATPase 5062855 ybhF1 10978780 ybhF1 Zobellia galactanivorans ABC transporter ATPase YP_004738757.1 5062127 R 63186 CDS YP_004738758.1 340620305 10978776 complement(5062852..5063754) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the permease component; Family membership; ABC transporter ATPase 5063754 ybhF2 10978776 ybhF2 Zobellia galactanivorans ABC transporter ATPase YP_004738758.1 5062852 R 63186 CDS YP_004738759.1 340620306 10978777 complement(5063751..5064647) 1 NC_015844.1 The membrane fusion proteins (MFP) belong to a multidrug efflux pump system that confer the resistance to compounds such as antibiotics, solvents or heavy metals; Proteins of the MFP family function as 'adaptors', connecting a ABC transporters, localized in the cytoplasmic membrane, with a porin or channel localized in outer membrane; The MFP proteins seem to be anchored in the cytoplasmic membrane by a N-terminal transmembrane region; Lipoprotein with a signal peptide cleaved between the residues 19 and 20; Belongs to the type I secretion system; Specificity unclear; membrane fusion protein 5064647 ybhG 10978777 ybhG Zobellia galactanivorans membrane fusion protein YP_004738759.1 5063751 R 63186 CDS YP_004738760.1 340620307 10978778 complement(5064659..5065906) 1 NC_015844.1 The outer membrane efflux proteins (OEP) are composed of two repeats of OEP domain to form a trimeric channel continuous, solvent-accessible conduit that spans both the outer membrane and periplasmic space; May be specialized for the signal peptide independent extracellular secretion of a variety of substrates in Gram-negative bacteria (type I secretion system); Signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Family membership; outer membrane efflux protein 5065906 10978778 zobellia_4346 Zobellia galactanivorans outer membrane efflux protein YP_004738760.1 5064659 R 63186 CDS YP_004738761.1 340620308 10976774 complement(5065908..5066522) 1 NC_015844.1 Contains 1 HTH tetR-type DNA-binding domain (1 to 42) with an helix-turn-helix (HTH) motif (5 to 24); This domain is present in the N-terminal extremity of the tetR family of prokaryotic transcription regulators. The C-terminal part of these regulators contains several regions that can be involved in binding of inducers, which can be antibiotics, antiseptics, disinfectants or host-encoded antimicrobials; Family membership; TetR family transcriptional regulator 5066522 10976774 zobellia_4347 Zobellia galactanivorans TetR family transcriptional regulator YP_004738761.1 5065908 R 63186 CDS YP_004738762.1 340620309 10976775 5066825..5067751 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5067751 10976775 zobellia_4348 Zobellia galactanivorans hypothetical protein YP_004738762.1 5066825 D 63186 CDS YP_004738763.1 340620310 10976776 5067810..5068505 1 NC_015844.1 Contains a signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 5068505 10976776 zobellia_4349 Zobellia galactanivorans hypothetical protein YP_004738763.1 5067810 D 63186 CDS YP_004738764.1 340620311 10976777 5068664..5069938 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5069938 10976777 zobellia_4350 Zobellia galactanivorans hypothetical protein YP_004738764.1 5068664 D 63186 CDS YP_004738765.1 340620312 10976779 5070008..5070172 1 NC_015844.1 Hypothetical protein; hypothetical protein 5070172 10976779 zobellia_4351 Zobellia galactanivorans hypothetical protein YP_004738765.1 5070008 D 63186 CDS YP_004738766.1 340620313 10976780 complement(5070889..5071506) 1 NC_015844.1 Contains a putative lipoprotein signal peptide cleaved between the residues 17 and 18; Possibly localized in the outer membrane; Hypothetical protein; hypothetical protein 5071506 10976780 zobellia_4352 Zobellia galactanivorans hypothetical protein YP_004738766.1 5070889 R 63186 CDS YP_004738767.1 340620314 10976781 complement(5071503..5072606) 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases (GT4); Localized in the cytoplasm; Specificity unclear; glycosyltransferase 5072606 10976781 zobellia_4353 Zobellia galactanivorans glycosyltransferase YP_004738767.1 5071503 R 63186 CDS YP_004738768.1 340620315 10976782 complement(5072606..5073013) 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 5073013 10976782 zobellia_4354 Zobellia galactanivorans hypothetical protein YP_004738768.1 5072606 R 63186 CDS YP_004738769.1 340620316 10976783 complement(5073019..5073972) 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5073972 10976783 zobellia_4355 Zobellia galactanivorans hypothetical protein YP_004738769.1 5073019 R 63186 CDS YP_004738770.1 340620317 10976784 complement(5073974..5075128) 1 NC_015844.1 Glycosyltransferase catalyses the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Belongs to the family 4 of the glycosyltransferases (GT4); Localized in the cytoplasm; Specificity unclear; glycosyltransferase 5075128 10976784 zobellia_4356 Zobellia galactanivorans glycosyltransferase YP_004738770.1 5073974 R 63186 CDS YP_004738771.1 340620318 10976785 complement(5075131..5075685) 1 NC_015844.1 The exact molecular function of this protein is unknown; Belongs to the LemA family; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Family membership; LemA family protein 5075685 10976785 zobellia_4357 Zobellia galactanivorans LemA family protein YP_004738771.1 5075131 R 63186 CDS YP_004738772.1 340620319 10976786 5075927..5076526 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5076526 10976786 zobellia_4358 Zobellia galactanivorans hypothetical protein YP_004738772.1 5075927 D 63186 CDS YP_004738773.1 340620320 10976787 5076549..5076779 1 NC_015844.1 Hypothetical protein; hypothetical protein 5076779 10976787 zobellia_4359 Zobellia galactanivorans hypothetical protein YP_004738773.1 5076549 D 63186 CDS YP_004738774.1 340620321 10976788 complement(5076760..5077200) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5077200 10976788 zobellia_4360 Zobellia galactanivorans periplasmic protein YP_004738774.1 5076760 R 63186 CDS YP_004738775.1 340620322 10976790 5077798..5078685 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase) encoded by a different gene of those that encode for the ABC transporter permease component (ABC membrane); Family membership; ABC transporter ATPase 5078685 10976790 zobellia_4361 Zobellia galactanivorans ABC transporter ATPase YP_004738775.1 5077798 D 63186 CDS YP_004738776.1 340620323 10976791 5078718..5082362 1 NC_015844.1 Integral membrane protein with a C-terminal aminopeptidase domain. Belongs to the family M1 of the peptidase. A catalytic zinc ion is bound by two histidines and a glutamate. The histidines are within an 'HEXXH' motif on one long helix with the glutamate on another antiparallel helix. The catalytic mechanism is believed to involve activation of a water molecule by the zinc ion. The glutamate of the HEXXH motif is known to be important for catalysis and a tyrosine may also be involved. Features 13 transmembrane helices.; Specificity unclear; aminopeptidase 5082362 10976791 zobellia_4362 Zobellia galactanivorans aminopeptidase YP_004738776.1 5078718 D 63186 CDS YP_004738777.1 340620324 10976792 complement(5082578..5084008) 1 NC_015844.1 Enzyme that uses electrons from H2S to reduce quinones with the use of NADP. S0 is oxidized to sulfite and water. This process confers resistance to heavy metals such as cadmium and cisplatin; Binds 1 FAD noncovalently as cofactors; Belongs to the Pyridine nucleotide- disulphide oxidoreductase family; Localized in the cytoplasm; High confidence in function and specificity; sulfide:quinone oxidoreductase 5084008 sqrA 10976792 sqrA Zobellia galactanivorans sulfide:quinone oxidoreductase YP_004738777.1 5082578 R 63186 CDS YP_004738778.1 340620325 10978609 5084185..5084694 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 5084694 10978609 zobellia_4364 Zobellia galactanivorans hypothetical protein YP_004738778.1 5084185 D 63186 CDS YP_004738779.1 340620326 10976793 5084994..5085131 1 NC_015844.1 Hypothetical protein; hypothetical protein 5085131 10976793 zobellia_4365 Zobellia galactanivorans hypothetical protein YP_004738779.1 5084994 D 63186 CDS YP_004738780.1 340620327 10976794 5085332..5085445 1 NC_015844.1 Hypothetical protein; hypothetical protein 5085445 10976794 zobellia_4366 Zobellia galactanivorans hypothetical protein YP_004738780.1 5085332 D 63186 CDS YP_004738781.1 340620328 10976795 complement(5085469..5085855) 1 NC_015844.1 Transcriptional regulator belonging to the Ferric uptake regulator or FUR family, which includes metal ion uptake regulator proteins, which bind to the operator DNA and control the transcription of metal ion-responsive genes. Localized in the cytoplasm.; Family membership; Fur-type transcriptional regulator 5085855 10976795 zobellia_4367 Zobellia galactanivorans Fur-type transcriptional regulator YP_004738781.1 5085469 R 63186 CDS YP_004738782.1 340620329 10976796 5085935..5086339 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5086339 10976796 zobellia_4368 Zobellia galactanivorans membrane protein YP_004738782.1 5085935 D 63186 CDS YP_004738783.1 340620330 10976797 5086329..5086994 1 NC_015844.1 GTP cyclohydrolase I catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate. FolE is a homodecamer, composed of a dimer of pentamers. It is an allosteric enzyme, whose activity is modulated by K(+), divalent cations, UTP, and tetrahydrobiopterin. Tetrahydrobiopterin is an inhibitor of this enzyme. Localized in the cytoplasm.; High confidence in function and specificity; GTP cyclohydrolase I 5086994 folE3 10976797 folE3 Zobellia galactanivorans GTP cyclohydrolase I YP_004738783.1 5086329 D 63186 CDS YP_004738784.1 340620331 10977840 5087053..5087958 1 NC_015844.1 Conserved protein belonging to the CobW nucleotide binding domain family. Localized in the cytoplasm.; Function unclear; CobW-like nucleotide binding protein 5087958 10977840 zobellia_4370 Zobellia galactanivorans CobW-like nucleotide binding protein YP_004738784.1 5087053 D 63186 CDS YP_004738785.1 340620332 10976799 complement(5088223..5089632) 1 NC_015844.1 Alkaline phosphatase is a zinc and magnesium-containing metalloenzyme which hydrolyzes phosphate esters, optimally at high pH; Alkaline phosphatase exists as a dimer, each monomer binding 2 zinc atoms and one magnesium atom, which are essential for enzymic activity; Signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; High confidence in function and specificity; alkaline phosphatase 5089632 phoA 10976799 phoA Zobellia galactanivorans alkaline phosphatase YP_004738785.1 5088223 R 63186 CDS YP_004738786.1 340620333 10978345 complement(5089663..5090100) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 5090100 10978345 zobellia_4372 Zobellia galactanivorans hypothetical protein YP_004738786.1 5089663 R 63186 CDS YP_004738787.1 340620334 10976800 complement(5090090..5091331) 1 NC_015844.1 ABC (ATP-binding cassette) transporters are responsible for translocation of a variety of compounds across biological membranes; Contains four transmembrane segments; Localized in the cytoplasmic membrane; Family membership; ABC transporter permease 5091331 10976800 zobellia_4373 Zobellia galactanivorans ABC transporter permease YP_004738787.1 5090090 R 63186 CDS YP_004738788.1 340620335 10976801 complement(5091328..5091957) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasm near of the cytoplasmic membrane by association with the ABC transporter permease component; Family membership; ABC transporter ATPase 5091957 10976801 zobellia_4374 Zobellia galactanivorans ABC transporter ATPase YP_004738788.1 5091328 R 63186 CDS YP_004738789.1 340620336 10976802 complement(5091983..5093179) 1 NC_015844.1 The presence of P47K, also known as 47 kDa protein in Pseudomonas chlororaphis B23, is critical for the expression of the nitrile hydratase genes. May stabilize or activate the nitrile hydratase proteins. Features a N-terminal cobW-like nucleotide-binding domain and a cobW-like C-terminal domain. Localized in the cytoplasm.; Function unclear; P47K 5093179 10976802 zobellia_4375 Zobellia galactanivorans P47K YP_004738789.1 5091983 R 63186 CDS YP_004738790.1 340620337 10976803 complement(5093698..5094006) 1 NC_015844.1 Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5094006 10976803 zobellia_4376 Zobellia galactanivorans periplasmic protein YP_004738790.1 5093698 R 63186 CDS YP_004738791.1 340620338 10976804 complement(5094230..5094619) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; localized in the outer membrane; Hypothetical protein; hypothetical protein 5094619 10976804 zobellia_4377 Zobellia galactanivorans hypothetical protein YP_004738791.1 5094230 R 63186 CDS YP_004738792.1 340620339 10976805 complement(5095894..5096232) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5096232 10976805 zobellia_4378 Zobellia galactanivorans hypothetical protein YP_004738792.1 5095894 R 63186 CDS YP_004738793.1 340620340 10976806 complement(5096679..5096996) 1 NC_015844.1 Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5096996 10976806 zobellia_4379 Zobellia galactanivorans periplasmic protein YP_004738793.1 5096679 R 63186 CDS YP_004738794.1 340620341 10976807 5097146..5097655 1 NC_015844.1 Protein that could play an role in isoprenoid quinone metabolism and/or transport and/or storage; Belongs to the YceI family; Signal peptide cleaved between the residues 27 and 28; Localized in the periplasmic space; Function unclear; periplasmic protein 5097655 10976807 zobellia_4380 Zobellia galactanivorans periplasmic protein YP_004738794.1 5097146 D 63186 CDS YP_004738795.1 340620342 10976809 5097774..5098730 1 NC_015844.1 Alx is a protein that could be induced by extreme alkaline conditions. The exact function of Alx is unknown. A number of conserved aspartates may be involved in metal ion binding; Belongs to the TerC family; Contains nine transmembrane helices; Localized in the cytoplasmic membrane; Family membership; inner membrane protein alx 5098730 alx 10976809 alx Zobellia galactanivorans inner membrane protein alx YP_004738795.1 5097774 D 63186 CDS YP_004738796.1 340620343 10977510 complement(5098773..5099243) 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5099243 10977510 zobellia_4382 Zobellia galactanivorans hypothetical protein YP_004738796.1 5098773 R 63186 CDS YP_004738797.1 340620344 10976810 complement(5099203..5099457) 1 NC_015844.1 Acyl carrier protein (ACP) is the carrier of the growing fatty acid chain in fatty acid biosynthesis. ACP is produced as an apoprotein and is converted to its active form by [ACP]synthase (AcpS); Localized in the cytoplasm; High confidence in function and specificity; acyl carrier protein 5099457 acpP4 10976810 acpP4 Zobellia galactanivorans acyl carrier protein YP_004738797.1 5099203 R 63186 CDS YP_004738798.1 340620345 10977468 complement(5099494..5100768) 1 NC_015844.1 3-oxoacyl-[acyl-carrier-protein] synthase, also known as beta-ketoacyl synthase, catalyzes the condensation reaction of fatty acid synthesis by the addition of two carbons from malonyl-ACP to an acyl acceptor. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids; Belongs to the Beta-ketoacyl synthase family; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP synthase 5100768 fabB7 10977468 fabB7 Zobellia galactanivorans 3-oxoacyl-ACP synthase YP_004738798.1 5099494 R 63186 CDS YP_004738799.1 340620346 10977799 complement(5100761..5101201) 1 NC_015844.1 (3R)-Hydroxymyristoyl-[acyl-carrier-protein] dehydratase (FabZ) catalyses the dehydratation of beta-hydroxyacyl-ACP generated by FabG to trans-2-enoyl-ACP. This is the third step of the fatty acid elongation cycle. FabZ forms a hexamer (a trimer of dimers)and the monomer adopts a beta + alpha \\hotdog\\ fold; Localized in the cytoplasm; High confidence in function and specificity; (3R)-hydroxymyristoyl-ACP dehydratase 5101201 fabZ3 10977799 fabZ3 Zobellia galactanivorans (3R)-hydroxymyristoyl-ACP dehydratase YP_004738799.1 5100761 R 63186 CDS YP_004738800.1 340620347 10977811 complement(5101255..5102031) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 5102031 10977811 zobellia_4386 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004738800.1 5101255 R 63186 CDS YP_004738801.1 340620348 10976811 complement(5102065..5103120) 1 NC_015844.1 Type III polyketide synthases are homodimeric enzymes that iteratively carry out the polyketide synthesis at one single active site; Belongs to the chalcone/stilbene synthase family; Localized in the cytoplasm; Specificity unclear; type III polyketide synthase 5103120 10976811 zobellia_4387 Zobellia galactanivorans type III polyketide synthase YP_004738801.1 5102065 R 63186 CDS YP_004738802.1 340620349 10976812 complement(5103137..5103841) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5103841 10976812 zobellia_4388 Zobellia galactanivorans hypothetical protein YP_004738802.1 5103137 R 63186 CDS YP_004738803.1 340620350 10976813 complement(5103842..5104963) 1 NC_015844.1 Aromatic-ring hydroxylases (or monooxygenases) catalyze the incorporation of one atom of dioxygen into an aromatic compound and the reduction of the other oxygen atom to water. These oxidoreductases are FAD-dependent and adopt a Rossmann fold; Belongs to the pyridine nucleotide-disulphide reductases superfamily; Localized in the cytoplasm; Specificity unclear; aromatic-ring hydroxylase 5104963 10976813 zobellia_4389 Zobellia galactanivorans aromatic-ring hydroxylase YP_004738803.1 5103842 R 63186 CDS YP_004738804.1 340620351 10976814 complement(5105054..5105749) 1 NC_015844.1 Modular protein that contains a N-terminal Rickettsia 17 kDa surface antigen-like domain and a C-terminal OmpA-like domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Contains three transmembrane helices; Localized in the cytoplasmic membrane; Function unclear; OmpA-like membrane protein 5105749 10976814 zobellia_4390 Zobellia galactanivorans OmpA-like membrane protein YP_004738804.1 5105054 R 63186 CDS YP_004738805.1 340620352 10976816 complement(5105760..5106242) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; localized in the outer membrane; Conserved hypothetical protein; lipoprotein 5106242 10976816 zobellia_4391 Zobellia galactanivorans lipoprotein YP_004738805.1 5105760 R 63186 CDS YP_004738806.1 340620353 10976817 complement(5106383..5108359) 1 NC_015844.1 The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It is involved in valine, leucine and isoleucine biodegradation. This complex contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 component displays a modular architecture. The N-terminal domain is a dehydrogenase and the C-terminal domain belongs to the transketolase family. Both activities uses thiamine pyrophosphate as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity; 2-oxoisovalerate dehydrogenase, E1 component 5108359 bkdA1 10976817 bkdA1 Zobellia galactanivorans 2-oxoisovalerate dehydrogenase, E1 component YP_004738806.1 5106383 R 63186 CDS YP_004738807.1 340620354 10977606 5108489..5109439 1 NC_015844.1 Conserved dioxygenase of unknown specificity. Belongs to the 2OG-Fe(II) oxygenase superfamily, which includes various enzymes such as Leucoanthocyanidin dioxygenase, flavanone 3-hydroxylase and Gibberellin 20 oxidase. Localized in the cytoplasm.; Specificity unclear; dioxygenase 5109439 10977606 zobellia_4393 Zobellia galactanivorans dioxygenase YP_004738807.1 5108489 D 63186 CDS YP_004738808.1 340620355 10976818 5109442..5109771 1 NC_015844.1 Protein Belongs to the SUI1 family; Localized in the cytoplasm; Family membership; protein translation factor SUI1-like protein 5109771 yciH 10976818 yciH Zobellia galactanivorans protein translation factor SUI1-like protein YP_004738808.1 5109442 D 63186 CDS YP_004738809.1 340620356 10978782 5109890..5110822 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5110822 10978782 zobellia_4395 Zobellia galactanivorans hypothetical protein YP_004738809.1 5109890 D 63186 CDS YP_004738810.1 340620357 10976819 5110827..5111699 1 NC_015844.1 Uridine phosphorylase catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis; Forms a homohexamer; Localized in the cytoplasm; High confidence in function and specificity; uridine phosphorylase 5111699 udpA 10976819 udpA Zobellia galactanivorans uridine phosphorylase YP_004738810.1 5110827 D 63186 CDS YP_004738811.1 340620358 10978722 5111825..5112682 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5112682 10978722 zobellia_4397 Zobellia galactanivorans hypothetical protein YP_004738811.1 5111825 D 63186 CDS YP_004738812.1 340620359 10976820 5112757..5113188 1 NC_015844.1 Contains a signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5113188 10976820 zobellia_4398 Zobellia galactanivorans periplasmic protein YP_004738812.1 5112757 D 63186 CDS YP_004738813.1 340620360 10976821 complement(5113178..5113843) 1 NC_015844.1 Uracil-DNA glycosylase excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase to form U:A pairs or due to deamination of cytosine to form mutagenic U:G mispairs. These aberrant uracil residues are genotoxic; Belongs to the uracil-DNA glycosylase family; Localized in the cytoplasm; High confidence in function and specificity; uracil-DNA glycosylase 5113843 ungA 10976821 ungA Zobellia galactanivorans uracil-DNA glycosylase YP_004738813.1 5113178 R 63186 CDS YP_004738814.1 340620361 10978727 5113983..5114492 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; localized in the outer membrane; Conserved hypothetical protein; lipoprotein 5114492 10978727 zobellia_4400 Zobellia galactanivorans lipoprotein YP_004738814.1 5113983 D 63186 CDS YP_004738815.1 340620362 10976823 5114571..5116745 1 NC_015844.1 The MutS protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity; Contains a central MutS_V domain; Belongs to the MutS family; localized in the cytoplasm; High confidence in function and specificity; DNA mismatch repair protein MutS 5116745 mutS2 10976823 mutS2 Zobellia galactanivorans DNA mismatch repair protein MutS YP_004738815.1 5114571 D 63186 CDS YP_004738816.1 340620363 10978213 5116853..5117260 1 NC_015844.1 Conserved protein belonging to the DUF393 family. Proteins in this family are predicted to have a thioredoxin-like fold which, together with the presence of an invariant catalytic cysteine residue, suggesting that they are a novel group of thiol-disulphide oxidoreductases. Localized in the cytoplasm.; hypothetical protein 5117260 10978213 zobellia_4402 Zobellia galactanivorans hypothetical protein YP_004738816.1 5116853 D 63186 CDS YP_004738817.1 340620364 10976824 complement(5117306..5118592) 1 NC_015844.1 Carrier protein which is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system. GltT participates in nutrient uptake; Forms a homotrimer; Contains six transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; proton/sodium-glutamate symporter 5118592 gltT 10976824 gltT Zobellia galactanivorans proton/sodium-glutamate symporter YP_004738817.1 5117306 R 63186 CDS YP_004738818.1 340620365 10977932 complement(5118730..5119800) 1 NC_015844.1 Chorismate synthase is involved in the last of the seven steps in the shikimate pathway which is used for the biosynthesis of aromatic amino acids. It catalyzes the 1, 4- trans elimination of the phosphate group from 5-enolpyruvylshikimate-3-phosphate to form chorismate which can then be used in phenylalanine, tyrosine or tryptophan biosynthesis. Uses the reduced flavin mononucleotide (FMNH2 or FADH2) as prosthetic group; Forms a homotetramer; Localized in the cytoplasm; High confidence in function and specificity; chorismate synthase 5119800 aroC 10977932 aroC Zobellia galactanivorans chorismate synthase YP_004738818.1 5118730 R 63186 CDS YP_004738819.1 340620366 10977546 5120155..5121015 1 NC_015844.1 Conserved protein belonging to the metallophosphoesterase family. The most conserved regions in this family centre around the metal chelating residues; Localized in the cytoplasm; Family membership; metallophosphoesterase 5121015 10977546 zobellia_4405 Zobellia galactanivorans metallophosphoesterase YP_004738819.1 5120155 D 63186 CDS YP_004738820.1 340620367 10976825 complement(5121021..5123930) 1 NC_015844.1 Conserved protein containing a N-terminal FAD-dependent oxidoreductase domain and a C-terminal domain containing a 4Fe-4S cluster. These domains are distantly related to the D-lactate dehydrogenase and the subunit C of the glycerol-3-phosphate dehydrogenase, respectively. The function of this modular protein is unknown.; Function unclear; FAD-dependent oxidoreductase 5123930 10976825 zobellia_4406 Zobellia galactanivorans FAD-dependent oxidoreductase YP_004738820.1 5121021 R 63186 CDS YP_004738821.1 340620368 10976826 5124018..5124536 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5124536 10976826 zobellia_4407 Zobellia galactanivorans periplasmic protein YP_004738821.1 5124018 D 63186 CDS YP_004738822.1 340620369 10976827 5124637..5125755 1 NC_015844.1 Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Belongs to the thioredoxin family; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; localized in the outer membrane; High confidence in function and specificity; thiol-disulfide oxidoreductase 5125755 10976827 zobellia_4408 Zobellia galactanivorans thiol-disulfide oxidoreductase YP_004738822.1 5124637 D 63186 CDS YP_004738823.1 340620370 10976828 complement(5125832..5127472) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; localized in the outer membrane; Conserved hypothetical protein; lipoprotein 5127472 10976828 zobellia_4409 Zobellia galactanivorans lipoprotein YP_004738823.1 5125832 R 63186 CDS YP_004738824.1 340620371 10976829 complement(5127652..5128302) 1 NC_015844.1 Serine endopeptidase belonging to the family S54. This family includes the protein Rhomboid which is a peptidase important for embryo development in Drosophila melanogaster. The active site is a catalytic diad Ser, His. Features seven transmembrane helices. Localized in the cytoplasmic membrane.; Specificity unclear; serine endopeptidase 5128302 10976829 zobellia_4410 Zobellia galactanivorans serine endopeptidase YP_004738824.1 5127652 R 63186 CDS YP_004738825.1 340620372 10976831 5128359..5129246 1 NC_015844.1 Lipid A biosynthesis lauroyl acyltransferase is involved in lipopolysaccharide biosynthesis. It transfers myristate or laurate, activated on ACP, to the lipid A moiety of (KDO)2-(lauroyl)-lipid IVA during lipopolysaccharide core biosynthesis. Features a N-terminal transmembrane helix. Localized in the cytoplasmic membrane.; High confidence in function and specificity; lipid A biosynthesis lauroyl acyltransferase 5129246 htrB 10976831 htrB Zobellia galactanivorans lipid A biosynthesis lauroyl acyltransferase YP_004738825.1 5128359 D 63186 CDS YP_004738826.1 340620373 10978002 complement(5129420..5130808) 1 NC_015844.1 AlgC catalyzes the interconversion between mannose-6-phosphate and alpha-mannose-1-phosphate. It has also a phosphoglucomutase activity interconverting glucose-6-phosphate and alpha-glucose-1-phosphate. Likely involved in EPS/LPS biosynthesis. Binds one magnesium as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; phosphomannomutase/phosphoglucomutase 5130808 algC 10978002 algC Zobellia galactanivorans phosphomannomutase/phosphoglucomutase YP_004738826.1 5129420 R 63186 CDS YP_004738827.1 340620374 10977501 5130884..5131468 1 NC_015844.1 Acyl carrier protein phosphodiesterase is involved in fatty acid biosynthesis. It converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP. Localized in the cytoplasm.; High confidence in function and specificity; acyl carrier protein phosphodiesterase 5131468 acpH 10977501 acpH Zobellia galactanivorans acyl carrier protein phosphodiesterase YP_004738827.1 5130884 D 63186 CDS YP_004738828.1 340620375 10977464 5131530..5133233 1 NC_015844.1 Gamma-glutamyltranspeptidase is a threonine peptidase that catalyzes the transfer of the gamma-glutamyl moiety of glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate). GgtA plays a key role in the gamma-glutamyl cycle, a pathway for the synthesis and degradation of glutathione. This enzyme consists of two polypeptide chains, a heavy and a light subunit, processed from a single chain precursor; Belongs to the family T3 of the peptidases; Putative lipoprotein signal peptide cleaved between the residues 19 and 20; Possibly localized in the outer membrane; High confidence in function and specificity; gamma-glutamyltranspeptidase 5133233 ggtA 10977464 ggtA Zobellia galactanivorans gamma-glutamyltranspeptidase YP_004738828.1 5131530 D 63186 CDS YP_004738829.1 340620376 10977895 5133244..5133960 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5133960 10977895 zobellia_4415 Zobellia galactanivorans membrane protein YP_004738829.1 5133244 D 63186 CDS YP_004738830.1 340620377 10976832 complement(5133987..5134163) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5134163 10976832 zobellia_4416 Zobellia galactanivorans hypothetical protein YP_004738830.1 5133987 R 63186 CDS YP_004738831.1 340620378 10976833 5134303..5135043 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5135043 10976833 zobellia_4417 Zobellia galactanivorans hypothetical protein YP_004738831.1 5134303 D 63186 CDS YP_004738832.1 340620379 10976834 5135118..5135723 1 NC_015844.1 Contains a signal peptide cleaved between the residues 33 and 34; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 5135723 10976834 zobellia_4418 Zobellia galactanivorans hypothetical protein YP_004738832.1 5135118 D 63186 CDS YP_004738833.1 340620380 10976835 complement(5135842..5136975) 1 NC_015844.1 Protein belonging to the zinc-dependent beta-lactamase superfamily. The active site is characterized by several conserved histidines binding the catalytic zinc ions. The enzymes can bind one or two zinc ions; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Specificity unclear; metallo-beta-lactamase superfamily protein 5136975 10976835 zobellia_4419 Zobellia galactanivorans metallo-beta-lactamase superfamily protein YP_004738833.1 5135842 R 63186 CDS YP_004738834.1 340620381 10976836 complement(5136980..5137798) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 5137798 10976836 zobellia_4420 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004738834.1 5136980 R 63186 CDS YP_004738835.1 340620382 10976838 complement(5138003..5138647) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 5138647 10976838 zobellia_4421 Zobellia galactanivorans hypothetical protein YP_004738835.1 5138003 R 63186 CDS YP_004738836.1 340620383 10976839 complement(5138716..5138973) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5138973 10976839 zobellia_4422 Zobellia galactanivorans hypothetical protein YP_004738836.1 5138716 R 63186 CDS YP_004738837.1 340620384 10976840 complement(5139153..5139617) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5139617 10976840 zobellia_4423 Zobellia galactanivorans hypothetical protein YP_004738837.1 5139153 R 63186 CDS YP_004738838.1 340620385 10976841 complement(5140253..5140876) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5140876 10976841 zobellia_4424 Zobellia galactanivorans hypothetical protein YP_004738838.1 5140253 R 63186 CDS YP_004738839.1 340620386 10976842 complement(5141136..5141906) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Specificity unclear; short-chain dehydrogenase/reductase 5141906 10976842 zobellia_4425 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004738839.1 5141136 R 63186 CDS YP_004738840.1 340620387 10976843 complement(5142060..5142398) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5142398 10976843 zobellia_4426 Zobellia galactanivorans hypothetical protein YP_004738840.1 5142060 R 63186 CDS YP_004738841.1 340620388 10976844 complement(5142410..5142889) 1 NC_015844.1 Dsp protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction; Forms a homododecamer and the 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe(3+) can be deposited; Localized in the cytoplasm; High confidence in function and specificity; DNA protection during starvation protein 5142889 dpsA4 10976844 dpsA4 Zobellia galactanivorans DNA protection during starvation protein YP_004738841.1 5142410 R 63186 CDS YP_004738842.1 340620389 10977765 complement(5142895..5144238) 1 NC_015844.1 Protein with a N-terminal domain belonging to the metallo-beta-lactamase superfamily and two rhodanese (thiosulfate sulfurtransferase) domains: one where the active-site cysteine residue is replaced by another aminoacid whereas the C-terminal domain displays the catalytic cysteine residue. The active site of the metallo-beta-lactamase domain is characterized by several conserved histidines binding the catalytic zinc ions. The enzymes can bind one or two zinc ions; Localized in the cytoplasm; Function unclear; metallo-beta-lactamase superfamily protein 5144238 10977765 zobellia_4428 Zobellia galactanivorans metallo-beta-lactamase superfamily protein YP_004738842.1 5142895 R 63186 CDS YP_004738843.1 340620390 10976845 5144330..5144605 1 NC_015844.1 This protein corresponds to a central fragment of an hypothetical protein from Kordia algicida and is likely an inactive pseudogene; Localized in the cytoplasm; Hypothetical protein; hypothetical protein 5144605 10976845 zobellia_4429 Zobellia galactanivorans hypothetical protein YP_004738843.1 5144330 D 63186 CDS YP_004738844.1 340620391 10976846 5144624..5144779 1 NC_015844.1 Hypothetical protein; hypothetical protein 5144779 10976846 zobellia_4430 Zobellia galactanivorans hypothetical protein YP_004738844.1 5144624 D 63186 CDS YP_004738845.1 340620392 10976848 complement(5144931..5145434) 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5145434 10976848 zobellia_4431 Zobellia galactanivorans hypothetical protein YP_004738845.1 5144931 R 63186 CDS YP_004738846.1 340620393 10976849 complement(5145589..5146053) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5146053 10976849 zobellia_4432 Zobellia galactanivorans hypothetical protein YP_004738846.1 5145589 R 63186 CDS YP_004738847.1 340620394 10976850 complement(5146673..5147122) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 23 and 24; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5147122 10976850 zobellia_4433 Zobellia galactanivorans periplasmic protein YP_004738847.1 5146673 R 63186 CDS YP_004738848.1 340620395 10976851 complement(5147177..5147710) 1 NC_015844.1 Protein homologous to the C-terminal domain of the deaminase-reductase RidB. The exact function of this protein is unknown; Localized in the cytoplasm; Function unclear; RibD C-terminal domain family protein 5147710 10976851 zobellia_4434 Zobellia galactanivorans RibD C-terminal domain family protein YP_004738848.1 5147177 R 63186 CDS YP_004738849.1 340620396 10976852 complement(5147863..5148981) 1 NC_015844.1 Histidine decarboxylase catalyzes the decarboxylation of L-histidine releasing histamine, a siderophore precursor. This enzyme covalently binds the cofactor pyridoxal-phosphate (PLP) on a conserved lysine. Localized in the cytoplasm.; High confidence in function and specificity; histidine decarboxylase 5148981 hdc 10976852 hdc Zobellia galactanivorans histidine decarboxylase YP_004738849.1 5147863 R 63186 CDS YP_004738850.1 340620397 10977961 5149140..5149592 1 NC_015844.1 The AsnC/Lrp-type transcriptional regulator family appears to be an important regulatory system of the amino acid metabolism and related processes; Contains a N-terminal DNA binding AsnC/Lrp-type HTH domain. The C-terminal part contains an effector-binding domain and/or an oligomerization domain; Localized in the cytoplasm; Family membership; AsnC/Lrp-type transcriptional regulator 5149592 10977961 zobellia_4436 Zobellia galactanivorans AsnC/Lrp-type transcriptional regulator YP_004738850.1 5149140 D 63186 CDS YP_004738851.1 340620398 10976853 complement(5149661..5150461) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5150461 10976853 zobellia_4437 Zobellia galactanivorans hypothetical protein YP_004738851.1 5149661 R 63186 CDS YP_004738852.1 340620399 10976854 complement(5150685..5151569) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5151569 10976854 zobellia_4438 Zobellia galactanivorans hypothetical protein YP_004738852.1 5150685 R 63186 CDS YP_004738853.1 340620400 10976855 complement(5151760..5152311) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5152311 10976855 zobellia_4439 Zobellia galactanivorans hypothetical protein YP_004738853.1 5151760 R 63186 CDS YP_004738854.1 340620401 10976856 complement(5152457..5153233) 1 NC_015844.1 Transcriptional regulator belonging to the LuxR family. Features a C-terminal helix-turn-helix DNA binding motif. Localized in the cytoplasm.; Specificity unclear; LuxR-type transcriptional regulator 5153233 10976856 zobellia_4440 Zobellia galactanivorans LuxR-type transcriptional regulator YP_004738854.1 5152457 R 63186 CDS YP_004738855.1 340620402 10976858 complement(5153349..5154266) 1 NC_015844.1 The long chain dehydrogenases/reductases are zinc-containing enzymes. Zinc-dependant enzymes are dimeric or tetrameric enzymes that bind two atoms of zinc per subunit where one of the zinc atom is essential for catalytic activity while the other is not. The catalytic zinc is coordinated by two cysteines and one histidine; Contains a C-terminal domain having a classical Rossman-fold that reversibly binds NAD(H); The N-terminal domain of alcohol dehydrogenase-like proteins have a GroES-like fold; Localized in the cytoplasm; Family membership; long chain dehydrogenase/reductase 5154266 10976858 zobellia_4441 Zobellia galactanivorans long chain dehydrogenase/reductase YP_004738855.1 5153349 R 63186 CDS YP_004738856.1 340620403 10976859 complement(5154546..5155262) 1 NC_015844.1 Peroxiredoxins are thiol peroxidase. They are involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. The peroxidase reaction comprises two steps centered around a redox- active cysteine called the peroxidatic cysteine. It attacks the peroxide substrate and is oxidized to S-hydroxycysteine (a sulfenic acid). The second step is the regeneration of cysteine from S-hydroxycysteine. This regeneration is due to thiol-containing reductants such as thioredoxin. Localized in the cytoplasm.; Specificity unclear; peroxiredoxin 5155262 10976859 zobellia_4442 Zobellia galactanivorans peroxiredoxin YP_004738856.1 5154546 R 63186 CDS YP_004738857.1 340620404 10976860 complement(5155693..5156730) 1 NC_015844.1 The long chain dehydrogenases/reductases are zinc-containing enzymes. Zinc-dependant enzymes are dimeric or tetrameric enzymes that bind two atoms of zinc per subunit where one of the zinc atom is essential for catalytic activity while the other is not. The catalytic zinc is coordinated by two cysteines and one histidine; Contains a C-terminal domain having a classical Rossman-fold that reversibly binds NAD(H); The N-terminal domain of alcohol dehydrogenase-like proteins have a GroES-like fold; Localized in the cytoplasm; Family membership; long chain dehydrogenase/reductase 5156730 10976860 zobellia_4443 Zobellia galactanivorans long chain dehydrogenase/reductase YP_004738857.1 5155693 R 63186 CDS YP_004738858.1 340620405 10976861 complement(5156782..5158098) 1 NC_015844.1 Alpha-acetolactate decarboxylase is involved in ketone and acetoin biosynthesis. It converts acetolactate into acetoin: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2. Displays a C-terminal domain of unknown function. Features a signal peptide cleaved between the residues 20 and 21. Localized in the periplasm.; High confidence in function and specificity; alpha-acetolactate decarboxylase 5158098 aldB 10976861 aldB Zobellia galactanivorans alpha-acetolactate decarboxylase YP_004738858.1 5156782 R 63186 CDS YP_004738859.1 340620406 10977493 complement(5158111..5159085) 1 NC_015844.1 This family of integral membrane proteins are predicted to be permeases of unknown specificity (DUF318 family); Contains nine transmembrane helices; Localized in the cytoplasmic membrane; Family membership; permease 5159085 10977493 zobellia_4445 Zobellia galactanivorans permease YP_004738859.1 5158111 R 63186 CDS YP_004738860.1 340620407 10976862 complement(5159078..5159485) 1 NC_015844.1 Protein belonging to the OsmC family consisting of proteins involved in the stress and detoxification process; Localized in the cytoplasm; Family membership; OsmC-like protein 5159485 10976862 zobellia_4446 Zobellia galactanivorans OsmC-like protein YP_004738860.1 5159078 R 63186 CDS YP_004738861.1 340620408 10976863 complement(5159496..5159732) 1 NC_015844.1 Protein homologous to thioredoxins, glutaredoxins, and protein disulphide isomerases, and shares with them a redox-active disulphide. Localized in the cytoplasm.; Family membership; thioredoxin-like protein 5159732 10976863 zobellia_4447 Zobellia galactanivorans thioredoxin-like protein YP_004738861.1 5159496 R 63186 CDS YP_004738862.1 340620409 10976864 complement(5159850..5159978) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5159978 10976864 zobellia_4448 Zobellia galactanivorans hypothetical protein YP_004738862.1 5159850 R 63186 CDS YP_004738863.1 340620410 10976865 complement(5160185..5160394) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5160394 10976865 zobellia_4449 Zobellia galactanivorans hypothetical protein YP_004738863.1 5160185 R 63186 CDS YP_004738864.1 340620411 10976866 complement(5160408..5161400) 1 NC_015844.1 Protein belonging to the Sodium Bile acid symporter family; Contains eight transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear; sodium-dependent transporter 5161400 10976866 zobellia_4450 Zobellia galactanivorans sodium-dependent transporter YP_004738864.1 5160408 R 63186 CDS YP_004738865.1 340620412 10976868 complement(5161594..5161686) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5161686 10976868 zobellia_4451 Zobellia galactanivorans hypothetical protein YP_004738865.1 5161594 R 63186 CDS YP_004738866.1 340620413 10976869 5161791..5162054 1 NC_015844.1 Hypothetical protein; hypothetical protein 5162054 10976869 zobellia_4452 Zobellia galactanivorans hypothetical protein YP_004738866.1 5161791 D 63186 CDS YP_004738867.1 340620414 10976870 5162057..5162635 1 NC_015844.1 Protein Belongs to the YceI (UPF0312) family, type 1 subfamily; Signal peptide cleaved between the residues 25 and 26; Localized in the periplasmic space; Family membership; YceI family protein 5162635 10976870 zobellia_4453 Zobellia galactanivorans YceI family protein YP_004738867.1 5162057 D 63186 CDS YP_004738868.1 340620415 10976871 5162671..5163939 1 NC_015844.1 Contains a signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5163939 10976871 zobellia_4454 Zobellia galactanivorans periplasmic protein YP_004738868.1 5162671 D 63186 CDS YP_004738869.1 340620416 10976872 5164046..5164636 1 NC_015844.1 Protein Belongs to the YceI (UPF0312) family; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Family membership; YceI family protein 5164636 10976872 zobellia_4455 Zobellia galactanivorans YceI family protein YP_004738869.1 5164046 D 63186 CDS YP_004738870.1 340620418 10976873 complement(5164722..5165390) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Hypothetical protein; hypothetical protein 5165390 10976873 zobellia_4457 Zobellia galactanivorans hypothetical protein YP_004738870.1 5164722 R 63186 CDS YP_004738871.1 340620417 10976875 5165382..5165489 1 NC_015844.1 Hypothetical protein; hypothetical protein 5165489 10976875 zobellia_4456 Zobellia galactanivorans hypothetical protein YP_004738871.1 5165382 D 63186 CDS YP_004738872.1 340620419 10976874 complement(5165678..5166295) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5166295 10976874 zobellia_4458 Zobellia galactanivorans hypothetical protein YP_004738872.1 5165678 R 63186 CDS YP_004738873.1 340620420 10976876 5166743..5167192 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 5167192 10976876 zobellia_4459 Zobellia galactanivorans lipoprotein YP_004738873.1 5166743 D 63186 CDS YP_004738874.1 340620421 10976877 5167492..5168490 1 NC_015844.1 The alpha/beta hydrolase-fold proteins catalyse a wide range of enzymatic reactions. They are characterized by a catalytic triad, usually an serine, an aspartate acid, and an histidine. The core of enzyme is an alpha/beta-sheet (rather than a barrel), containing 8 strands connected by helices; Belongs to alpha/beta hydrolase superfamily; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Function unclear; alpha/beta hydrolase-fold protein 5168490 10976877 zobellia_4460 Zobellia galactanivorans alpha/beta hydrolase-fold protein YP_004738874.1 5167492 D 63186 CDS YP_004738875.1 340620422 10976879 complement(5168570..5169850) 1 NC_015844.1 Protein belonging to the family 12 of serine peptidases (S12). The active site residues Ser and Lys form the catalytic dyad and are found in the motif Ser-Xaa-Thr-Lys; Signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; Function unclear; serine peptidase 5169850 10976879 zobellia_4461 Zobellia galactanivorans serine peptidase YP_004738875.1 5168570 R 63186 CDS YP_004738876.1 340620423 10976880 5170080..5171285 1 NC_015844.1 Protein belonging to the DUF1006 family; Localized in the cytoplasm; Family membership; hypothetical protein 5171285 10976880 zobellia_4462 Zobellia galactanivorans hypothetical protein YP_004738876.1 5170080 D 63186 CDS YP_004738877.1 340620424 10976881 5171333..5171740 1 NC_015844.1 Metallothiol transferase confers resistance to fosfomycin by catalyzing the addition of a thiol group to fosfomycin. L-cysteine is probably the physiological thiol donor; Forms a homodimer; Binds a magnesium ion as cofactor per subunit; elongs to the Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Localized in the cytoplasm; High confidence in function and specificity; metallothiol transferase FosB 5171740 fosB 10976881 fosB Zobellia galactanivorans metallothiol transferase FosB YP_004738877.1 5171333 D 63186 CDS YP_004738878.1 340620425 10977843 5171814..5172686 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 5172686 10977843 zobellia_4464 Zobellia galactanivorans AraC family transcriptional regulator YP_004738878.1 5171814 D 63186 CDS YP_004738879.1 340620426 10976882 5172798..5173643 1 NC_015844.1 YtfG belongs to the NmrA-type oxidoreductase family, but its exact function is unknown; Localized in the cytoplasm; Family membership; oxidoreductase YtfG 5173643 ytfG 10976882 ytfG Zobellia galactanivorans oxidoreductase YtfG YP_004738879.1 5172798 D 63186 CDS YP_004738880.1 340620427 10978793 5173815..5174312 1 NC_015844.1 Protein Belongs to the Glyoxalase superfamily protein; Localized in the cytoplasm; Function unclear; glyoxalase superfamily protein 5174312 10978793 zobellia_4466 Zobellia galactanivorans glyoxalase superfamily protein YP_004738880.1 5173815 D 63186 CDS YP_004738881.1 340620428 10976883 5174518..5175381 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 5175381 10976883 zobellia_4467 Zobellia galactanivorans lipoprotein YP_004738881.1 5174518 D 63186 CDS YP_004738882.1 340620429 10976884 5175388..5175753 1 NC_015844.1 Protein with a Dimeric alpha-beta barrel domain that exhibit an alpha+beta sandwich fold with an antiparallel beta sheet that forms a closed barrel. These domains dimerise through the beta-sheet, and in some cases these dimers may assemble into higher oligomers; Localized in the cytoplasm; hypothetical protein 5175753 10976884 zobellia_4468 Zobellia galactanivorans hypothetical protein YP_004738882.1 5175388 D 63186 CDS YP_004738883.1 340620430 10976885 5175753..5175863 1 NC_015844.1 Hypothetical protein; hypothetical protein 5175863 10976885 zobellia_4469 Zobellia galactanivorans hypothetical protein YP_004738883.1 5175753 D 63186 CDS YP_004738884.1 340620431 10976886 5176124..5176798 1 NC_015844.1 Protein belonging to the Fatty acid hydroxylase family; Contains five transmembrane helices; Localized in the cytoplasmic membrane; Family membership; fatty acid hydroxylase family protein 5176798 10976886 zobellia_4470 Zobellia galactanivorans fatty acid hydroxylase family protein YP_004738884.1 5176124 D 63186 CDS YP_004738885.1 340620432 10976888 5176802..5178652 1 NC_015844.1 Modular protein with a N-terminal 3-oxoacyl-[acyl-carrier-protein] synthase III domain and a C-terminal domain of unknown function (211 residues). The 3-oxoacyl-[acyl-carrier-protein] synthase III, also known as beta-ketoacyl-ACP synthase III, catalyses the first condensation reaction in the fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of straight-chain of fatty acids instead of branched-chain; Localized in the cytoplasm; Specificity unclear; 3-oxoacyl-ACP synthase III 5178652 10976888 zobellia_4471 Zobellia galactanivorans 3-oxoacyl-ACP synthase III YP_004738885.1 5176802 D 63186 CDS YP_004738886.1 340620433 10976889 5178662..5179558 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5179558 10976889 zobellia_4472 Zobellia galactanivorans membrane protein YP_004738886.1 5178662 D 63186 CDS YP_004738887.1 340620434 10976890 complement(5179606..5179989) 1 NC_015844.1 Transcriptional regulator belonging to the HxlR family. Features a helix-turn-helix DNA binding motif. Localized in the cytoplasm.; Specificity unclear; HxlR-type transcriptional regulator 5179989 10976890 zobellia_4473 Zobellia galactanivorans HxlR-type transcriptional regulator YP_004738887.1 5179606 R 63186 CDS YP_004738888.1 340620435 10976891 5180232..5180885 1 NC_015844.1 Also called oxygen-insensitive NAD(P)H nitroreductase this enzyme reduces a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents, two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide); Uses the FMN as cofactor; Belongs to the nitroreductase family; Localized in the cytoplasm; High confidence in function and specificity; 6,7-dihydropteridine reductase 5180885 nfnB1 10976891 nfnB1 Zobellia galactanivorans 6,7-dihydropteridine reductase YP_004738888.1 5180232 D 63186 CDS YP_004738889.1 340620436 10978245 5180909..5181829 1 NC_015844.1 Protein that could be a lipase; Belongs to the alpha/beta hydrolase superfamily characterized by a catalytic triad, usually an serine, an aspartic acid, and an histidine and to the lipase/esterase LIP3/bchO family; localized in the cytoplasmic membrane; High confidence in function and specificity; Triacylglycerol lipase 5181829 lipA 10978245 lipA Zobellia galactanivorans Triacylglycerol lipase YP_004738889.1 5180909 D 63186 CDS YP_004738890.1 340620437 10978092 5181832..5182683 1 NC_015844.1 Hypothetical protein. Putatively localized in the cytoplasm.; hypothetical protein 5182683 10978092 zobellia_4476 Zobellia galactanivorans hypothetical protein YP_004738890.1 5181832 D 63186 CDS YP_004738891.1 340620438 10976892 5182715..5183338 1 NC_015844.1 Protein containing two consecutive domains Localized in the cytoplasm; Family membership; antibiotic biosynthesis monooxygenase family protein 5183338 10976892 zobellia_4477 Zobellia galactanivorans antibiotic biosynthesis monooxygenase family protein YP_004738891.1 5182715 D 63186 CDS YP_004738892.1 340620439 10976893 5183372..5184229 1 NC_015844.1 Alpha-acetolactate decarboxylase converts acetolactate into acetoin, which can be secreted by the cells. This may be a mechanism for controlling the internal pH of cells in the stationary stage; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in cytoplasmic and/or the outer membrane; High confidence in function and specificity; alpha-acetolactate decarboxylase 5184229 alsD 10976893 alsD Zobellia galactanivorans alpha-acetolactate decarboxylase YP_004738892.1 5183372 D 63186 CDS YP_004738893.1 340620440 10977509 5184237..5185799 1 NC_015844.1 Modular protein displaying a N-terminal 4-carboxymuconolactone decarboxylase (CMD) domain and a C-terminal conserved domain of unknown function. CMD is involved in protocatechuate catabolism. It converts the 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate to 4,5-dihydro-5-oxofuran-2-acetate; Localized in the cytoplasm:; High confidence in function and specificity; 4-carboxymuconolactone decarboxylase 5185799 pcaC 10977509 pcaC Zobellia galactanivorans 4-carboxymuconolactone decarboxylase YP_004738893.1 5184237 D 63186 CDS YP_004738894.1 340620441 10978309 5185819..5186757 1 NC_015844.1 The NADP-dependent quinone oxidoreductase catalyzes the one-electron reduction of certain quinines; orthoquinones are the best substrates. It is an enzyme found in bacteria, in yeast and in mammals where, in some species such as rodents, it has been recruited as an eye lens protein and is known as zeta-crystallin; Belongs to the zinc-containing alcohol dehydrogenase family, Quinone oxidoreductase subfamily; Localized in the cytoplasm; High confidence in function and specificity; quinone oxidoreductase 5186757 qorA1 10978309 qorA1 Zobellia galactanivorans quinone oxidoreductase YP_004738894.1 5185819 D 63186 CDS YP_004738895.1 340620442 10978426 5186777..5188273 1 NC_015844.1 Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm.; Family membership; NAD dependent aldehyde dehydrogenase 5188273 10978426 zobellia_4481 Zobellia galactanivorans NAD dependent aldehyde dehydrogenase YP_004738895.1 5186777 D 63186 CDS YP_004738896.1 340620443 10976895 5188302..5188445 1 NC_015844.1 Hypothetical protein; hypothetical protein 5188445 10976895 zobellia_4482 Zobellia galactanivorans hypothetical protein YP_004738896.1 5188302 D 63186 CDS YP_004738897.1 340620444 10976896 5188463..5189083 1 NC_015844.1 Members of this family are integral membrane proteins that includes the antibiotic resistance protein MarC. These proteins may be transporters; Belongs to the marC (UPF0056) family; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Family membership; multiple antibiotic resistance (MarC)-like protein 5189083 10976896 zobellia_4483 Zobellia galactanivorans multiple antibiotic resistance (MarC)-like protein YP_004738897.1 5188463 D 63186 CDS YP_004738898.1 340620445 10976897 5189110..5189487 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5189487 10976897 zobellia_4484 Zobellia galactanivorans hypothetical protein YP_004738898.1 5189110 D 63186 CDS YP_004738899.1 340620446 10976898 5189547..5190023 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 5190023 10976898 zobellia_4485 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004738899.1 5189547 D 63186 CDS YP_004738900.1 340620447 10976899 complement(5190031..5190795) 1 NC_015844.1 LexA represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. It displays a N-terminal Helix-Turn-Helix DNA binding domain and a C-terminal serine peptidase domain of the family S24. The HTH domain binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA- binding part of lexA, leading to derepression of the SOS regulon and eventually DNA repair. The active site of the S24 domain consists of a Ser, Lys catalytic dyad and the cleavage occurs at an Ala-Gly or a Cys-Gly bond. Localized in the cytoplasm.; High confidence in function and specificity; LexA repressor, family S24 5190795 lexA 10976899 lexA Zobellia galactanivorans LexA repressor, family S24 YP_004738900.1 5190031 R 63186 CDS YP_004738901.1 340620448 10978087 5190963..5192228 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 5192228 10978087 zobellia_4487 Zobellia galactanivorans hypothetical protein YP_004738901.1 5190963 D 63186 CDS YP_004738902.1 340620449 10976900 5192273..5193046 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 5193046 10976900 zobellia_4488 Zobellia galactanivorans hypothetical protein YP_004738902.1 5192273 D 63186 CDS YP_004738903.1 340620450 10976901 5193238..5196078 1 NC_015844.1 The UvrA protein belongs to the UvrABC repair system responsible of the recognition and processing of DNA lesions; UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate; Contains 2 ABC transporter domains; Belongs to the ABC transporter family; Localized in the cytoplasm; High confidence in function and specificity; excinuclease ABC subunit A 5196078 uvrA2 10976901 uvrA2 Zobellia galactanivorans excinuclease ABC subunit A YP_004738903.1 5193238 D 63186 CDS YP_004738904.1 340620451 10978732 5196121..5196669 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 5196669 10978732 zobellia_4490 Zobellia galactanivorans hypothetical protein YP_004738904.1 5196121 D 63186 CDS YP_004738905.1 340620452 10976903 5196855..5197541 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5197541 10976903 zobellia_4491 Zobellia galactanivorans hypothetical protein YP_004738905.1 5196855 D 63186 CDS YP_004738906.1 340620453 10976904 5197541..5200405 1 NC_015844.1 Protein displaying similarity with the metallopeptidases of the family 1 (M1), but lacking the catalytic HEXXH motif; Contains a C-terminal domain of unknown function; Signal peptide cleaved between the residues 28 and 29; Localized in the periplasmic space; Family membership; Non-peptidase protein 5200405 10976904 zobellia_4492 Zobellia galactanivorans Non-peptidase protein YP_004738906.1 5197541 D 63186 CDS YP_004738907.1 340620454 10976905 5200568..5202979 1 NC_015844.1 The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It is involved in valine, leucine and isoleucine biodegradation. This complex contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 component displays a modular architecture. The N-terminal domain is a dehydrogenase and the C-terminal domain belongs to the transketolase family. Both activities uses thiamine pyrophosphate as prosthetic group; Localized in the cytoplasm; High confidence in function and specificity; 2-oxoisovalerate dehydrogenase, E1 component 5202979 bkdA2 10976905 bkdA2 Zobellia galactanivorans 2-oxoisovalerate dehydrogenase, E1 component YP_004738907.1 5200568 D 63186 CDS YP_004738908.1 340620455 10977607 5203125..5203499 1 NC_015844.1 Contains four transmembrane helices; Belongs to the DoxX family; Localized in the cytoplasmic membrane; Family membership; membrane protein 5203499 10977607 zobellia_4494 Zobellia galactanivorans membrane protein YP_004738908.1 5203125 D 63186 CDS YP_004738909.1 340620456 10976906 complement(5203509..5204510) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 5204510 10976906 zobellia_4495 Zobellia galactanivorans hypothetical protein YP_004738909.1 5203509 R 63186 CDS YP_004738910.1 340620457 10976907 complement(5204489..5204638) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5204638 10976907 zobellia_4496 Zobellia galactanivorans hypothetical protein YP_004738910.1 5204489 R 63186 CDS YP_004738911.1 340620458 10976908 5204666..5204983 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5204983 10976908 zobellia_4497 Zobellia galactanivorans hypothetical protein YP_004738911.1 5204666 D 63186 CDS YP_004738912.1 340620459 10976909 5204996..5205997 1 NC_015844.1 Glycosyl transferase possibly involved in the cell wall biosynthesis; Belongs to the family 2 of glycosyl transferases (GT2); Localized in the cytoplasm; Family membership; glycosyl transferase 5205997 10976909 zobellia_4498 Zobellia galactanivorans glycosyl transferase YP_004738912.1 5204996 D 63186 CDS YP_004738913.1 340620460 10976910 5206101..5206949 1 NC_015844.1 Protein containing a C-terminal OmpA-like domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 17 and 18; Localized in the outer membrane; Family membership; OmpA-like lipoprotein 5206949 10976910 zobellia_4499 Zobellia galactanivorans OmpA-like lipoprotein YP_004738913.1 5206101 D 63186 CDS YP_004738914.1 340620461 10976911 complement(5207047..5207895) 1 NC_015844.1 Lipoprotein signal peptide cleaved between the residues 19 and 20; Putatively localized in the outer membrane; Hypothetical protein; hypothetical protein 5207895 10976911 zobellia_4500 Zobellia galactanivorans hypothetical protein YP_004738914.1 5207047 R 63186 CDS YP_004738915.1 340620462 10976914 complement(5207902..5210310) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (35-114) and the Plug module (130-237) acting as a channel gate; The signal peptide is cleaved between the residues 31 and 32; Family membership; TonB-dependent Receptor 5210310 10976914 zobellia_4501 Zobellia galactanivorans TonB-dependent Receptor YP_004738915.1 5207902 R 63186 CDS YP_004738916.1 340620463 10976915 5210558..5211100 1 NC_015844.1 Sigma factors are initiation factors of transcription that promote the attachment of RNA polymerase to promoters and are then released; They alter the specificity of promoter recognition; This family represents a group of sigma factors that are able to regulate extra cellular function (ECF). ECF-sigma factors all retain two features: the ability to respond to extra- cytoplasmic functions via the TonB-dependent transducer genes, and regulation by anti-sigma and anti-anti-sigma factors; Family membership; RNA polymerase ECF-type sigma factor 5211100 10976915 zobellia_4502 Zobellia galactanivorans RNA polymerase ECF-type sigma factor YP_004738916.1 5210558 D 63186 CDS YP_004738917.1 340620464 10976916 5211100..5211639 1 NC_015844.1 Contains a central transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5211639 10976916 zobellia_4503 Zobellia galactanivorans membrane protein YP_004738917.1 5211100 D 63186 CDS YP_004738918.1 340620465 10976917 5211614..5212711 1 NC_015844.1 Contains a signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5212711 10976917 zobellia_4504 Zobellia galactanivorans periplasmic protein YP_004738918.1 5211614 D 63186 CDS YP_004738919.1 340620466 10976918 5212948..5213616 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5213616 10976918 zobellia_4505 Zobellia galactanivorans periplasmic protein YP_004738919.1 5212948 D 63186 CDS YP_004738920.1 340620467 10976919 5213673..5213807 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5213807 10976919 zobellia_4506 Zobellia galactanivorans hypothetical protein YP_004738920.1 5213673 D 63186 CDS YP_004738921.1 340620468 10976920 5213865..5214587 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the cytoplasmic membrane; Conserved hypothetical protein; lipoprotein 5214587 10976920 zobellia_4507 Zobellia galactanivorans lipoprotein YP_004738921.1 5213865 D 63186 CDS YP_004738922.1 340620469 10976921 complement(5214595..5215194) 1 NC_015844.1 HisIE is a bifunctional enzyme containing a N-terminal phosphoribosyl-AMP cyclohydrolase (PRA-CH) domain and a C-terminal phosphoribosyl-ATP pyrophosphatase (PRA-PH) domain, catalyzing the third and second steps of the L-histidine biosynthetic pathway, respectively. PRA-CH catalyzes the reaction: 1-(5-phosphoribosyl)-AMP + H2O = 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide. It requires Zn ions for activity. PRA-PH catalyzes the reaction: 1-(5-phosphoribosyl)-ATP + H2O = 1-(5-phosphoribosyl)-AMP + diphosphate. Localized in the cytoplasm.; High confidence in function and specificity; histidine biosynthesis bifunctional protein HisIE 5215194 hisIE 10976921 hisIE Zobellia galactanivorans histidine biosynthesis bifunctional protein HisIE YP_004738922.1 5214595 R 63186 CDS YP_004738923.1 340620470 10977983 complement(5215251..5216006) 1 NC_015844.1 Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step in the L-histidine biosynthetic pathway, the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. IGPS is a heterodimer of HisF and HisH subunits. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. Localized in the cytoplasm.; High confidence in function and specificity; imidazole glycerol phosphate synthase subunit HisF 5216006 hisF 10977983 hisF Zobellia galactanivorans imidazole glycerol phosphate synthase subunit HisF YP_004738923.1 5215251 R 63186 CDS YP_004738924.1 340620471 10977980 complement(5216071..5216850) 1 NC_015844.1 HisA catalyzes the fourth step in the L-histidine biosynthetic pathway: 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide = 5-((5-phospho-1-deoxyribulos-1-ylamino)methylideneamino)- 1-(5-phosphoribosyl)imidazole-4-carboxamide. It forms a monomer and adopts a TIM barrel fold. Display distant similarity with HisF. Localized in the cytoplasm.; High confidence in function and specificity; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino] imidazole-4-carboxamide isomerase 5216850 hisA 10977980 hisA Zobellia galactanivorans 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino) methylideneamino] imidazole-4-carboxamide isomerase YP_004738924.1 5216071 R 63186 CDS YP_004738925.1 340620472 10977975 complement(5216979..5217329) 1 NC_015844.1 The function of this protein is not known, but a structural study indicates that each momonmer folds into an antiparallel four-helix bundle, while the overall protein is a homopentamer with a toroid-shaped structure containing a tapered central channel; Belongs to the bacterial 23S rRNA proteins family; Localized in the cytoplasm; Family membership; 23S rRNA protein 5217329 10977975 zobellia_4511 Zobellia galactanivorans 23S rRNA protein YP_004738925.1 5216979 R 63186 CDS YP_004738926.1 340620473 10976923 complement(5217367..5217954) 1 NC_015844.1 Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step in the L-histidine biosynthetic pathway, the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. IGPS is a heterodimer of HisF and HisH subunits. The hisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to hisF for the synthesis of IGP and AICAR. Localized in the cytoplasm.; High confidence in function and specificity; imidazole glycerol phosphate synthase subunit HisH 5217954 hisH 10976923 hisH Zobellia galactanivorans imidazole glycerol phosphate synthase subunit HisH YP_004738926.1 5217367 R 63186 CDS YP_004738927.1 340620474 10977982 complement(5218031..5219167) 1 NC_015844.1 HisB is a bifunctional enzyme containing a N-terminal histidinol-phosphatase (HP) domain and a C-terminal imidazoleglycerol-phosphate dehydratase (IGPD) domain, catalyzing the eighth and sixth steps of L-histidine biosynthetic pathway, respectively. HP catalyzes the dephosphorylation of L-histidinol phosphate. HP forms a homodimer in solution. The active site contains two metal binding sites. IGPD catalyzes the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O. IGPD is a metalloenzyme in which transition metals induce aggregation and are required for catalysis. Localized in the cytoplasm.; High confidence in function and specificity; histidine biosynthesis bifunctional protein HisB 5219167 hisB 10977982 hisB Zobellia galactanivorans histidine biosynthesis bifunctional protein HisB YP_004738927.1 5218031 R 63186 CDS YP_004738928.1 340620475 10977976 complement(5219187..5220236) 1 NC_015844.1 The histidinol-phosphate aminotransferase catalyses the transfer of an amino group from 3-(imidazol-4-yl)-2-oxopropyl phosphate to glutamic acid to form histidinol phosphate and 2-oxoglutarate using the Pyridoxal phosphate as cofactor bound by covalent linkage to a lysine residue. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. Localized in the cytoplasm.; High confidence in function and specificity; histidinol-phosphate aminotransferase 5220236 hisC 10977976 hisC Zobellia galactanivorans histidinol-phosphate aminotransferase YP_004738928.1 5219187 R 63186 CDS YP_004738929.1 340620476 10977977 complement(5220229..5221518) 1 NC_015844.1 Histidinol dehydrogenase catalyzes the terminal step in the biosynthesis of histidine, the four-electron oxidation of L-histidinol to histidine. A single active site catalyzes 2 separate oxidation steps: oxidation of the substrate alcohol to an intermediate aldehyde; and oxidation of the aldehyde to the product acid. The reaction proceeds via a tightly- or covalently-bound inter- mediate, and requires the presence of 2 NAD molecules. It forms a homodimer and binds also one zinc ion per subunit as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; histidinol dehydrogenase 5221518 hisD 10977977 hisD Zobellia galactanivorans histidinol dehydrogenase YP_004738929.1 5220229 R 63186 CDS YP_004738930.1 340620477 10977979 complement(5221515..5222000) 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule. Belongs to Gcn5 or GNAT actyltransferase family. Localized in the cytoplasm.; Specificity unclear; GCN5-like N-acetyltransferase 5222000 10977979 zobellia_4516 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004738930.1 5221515 R 63186 CDS YP_004738931.1 340620478 10976924 complement(5221973..5222830) 1 NC_015844.1 ATP phosphoribosyltransferase catalyzes the condensation of ATP and PRPP to form N'-5'-phosphoribosyl-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Exist in equilibrium between an active dimeric form, an inactive hexameric form and higher aggregates. Interconversion between the various forms is largely reversible and is influenced by the natural substrates and inhibitors of the enzyme. Binds a magnesium ion per subunit as cofactor. Localized in the cytoplasm.; High confidence in function and specificity; ATP phosphoribosyltransferase 5222830 hisG 10976924 hisG Zobellia galactanivorans ATP phosphoribosyltransferase YP_004738931.1 5221973 R 63186 CDS YP_004738932.1 340620479 10977981 5222961..5223053 1 NC_015844.1 Hypothetical protein; hypothetical protein 5223053 10977981 zobellia_4518 Zobellia galactanivorans hypothetical protein YP_004738932.1 5222961 D 63186 CDS YP_004738933.1 340620480 10976925 complement(5223067..5223879) 1 NC_015844.1 Conserved protein; Family membership; prohibitin-like protein 5223879 10976925 zobellia_4519 Zobellia galactanivorans prohibitin-like protein YP_004738933.1 5223067 R 63186 CDS YP_004738934.1 340620481 10976926 complement(5223890..5225920) 1 NC_015844.1 Contains two N-terminal transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5225920 10976926 zobellia_4520 Zobellia galactanivorans membrane protein YP_004738934.1 5223890 R 63186 CDS YP_004738935.1 340620482 10976928 complement(5225985..5226731) 1 NC_015844.1 FabG is involved in first reduction step of the fatty acid biosynthesis pathway. Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity; 3-oxoacyl-ACP reductase 5226731 fabG1 10976928 fabG1 Zobellia galactanivorans 3-oxoacyl-ACP reductase YP_004738935.1 5225985 R 63186 CDS YP_004738936.1 340620483 10977802 complement(5226847..5227719) 1 NC_015844.1 Succinyl-CoA ligase functions in the citric acid cycle, coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents an important site of substrate-level phosphorylation. It can also function in the other direction for anabolic purposes. It forms a heterotetramer of two alpha and two beta subunits. The alpha subunit binds CoA, as well as ATP and catalyzes phosphoryl transfer to one of its histidine residues. The complete active site is probably located in the region of alpha-beta contact. Localized in the cytoplasm.; High confidence in function and specificity; succinyl-CoA ligase [ADP-forming] subunit alpha 5227719 sucD 10977802 sucD Zobellia galactanivorans succinyl-CoA ligase [ADP-forming] subunit alpha YP_004738936.1 5226847 R 63186 CDS YP_004738937.1 340620484 10978617 complement(5227790..5228722) 1 NC_015844.1 LpxD catalyzes the third step of lipid A biosynthesis; LpxD features eight tandem repeats of a [LIV]-G-X(4) hexapeptide, which has been shown to fold as a left-handed parallel beta helix; Localized in the cytoplasm; High confidence in function and specificity; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 5228722 lpxD1 10978617 lpxD1 Zobellia galactanivorans UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_004738937.1 5227790 R 63186 CDS YP_004738938.1 340620485 10978105 complement(5228788..5229354) 1 NC_015844.1 Elongation factor P is involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. Localized in the cytoplasm.; High confidence in function and specificity; elongation factor P 5229354 efp 10978105 efp Zobellia galactanivorans elongation factor P YP_004738938.1 5228788 R 63186 CDS YP_004738939.1 340620486 10977776 complement(5229441..5230226) 1 NC_015844.1 LpxA catalyzes the first step of lipid A biosynthesis. LpxA features seven tandem repeats of a [LIV]-G-X(4) hexapeptide, which has been shown to fold as a left-handed parallel beta helix; Localized in the cytoplasm; High confidence in function and specificity; acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase 5230226 lpxA 10977776 lpxA Zobellia galactanivorans acyl-ACP--UDP-N- acetylglucosamine O-acyltransferase YP_004738939.1 5229441 R 63186 CDS YP_004738940.1 340620487 10978102 complement(5230228..5231613) 1 NC_015844.1 Modular protein consisting of a N-terminal UDP-3-O-[3-hydroxymyristoyl]-N-acetylglucosamine deacetylase domain (LpxC) and a C-terminal (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase domain (FabZ). LpxC catalyzes the second step of lipid A biosynthesis converting the UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine into UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine. LpxC is a zinc-dependent enzyme which belongs to the family 11 of the carbohydrate esterases (CE11). FabZ catalyzes the third step of the fatty acid elongation cycle (type II fatty acid biosynthesis) converting the (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] into tetradecenoyl-[acyl-carrier protein]. FabZ adopts a thioesterase fold; Localized in the cytoplasm; High confidence in function and specificity; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase 5231613 lpxC/fabZ4 10978102 lpxC/fabZ4 Zobellia galactanivorans UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase YP_004738940.1 5230228 R 63186 CDS YP_004738941.1 340620488 10978104 complement(5231594..5232643) 1 NC_015844.1 LpxD catalyzes the third step of lipid A biosynthesis; LpxD features eight tandem repeats of a [LIV]-G-X(4) hexapeptide, which has been shown to fold as a left-handed parallel beta helix; Localized in the cytoplasm; High confidence in function and specificity; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 5232643 lpxD2 10978104 lpxD2 Zobellia galactanivorans UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_004738941.1 5231594 R 63186 CDS YP_004738942.1 340620489 10978106 complement(5232667..5233770) 1 NC_015844.1 Conserved protein belonging to the metal-dependent phosphohydrolase family. Localized in the cytoplasm.; Family membership; phosphohydrolase family protein 5233770 10978106 zobellia_4528 Zobellia galactanivorans phosphohydrolase family protein YP_004738942.1 5232667 R 63186 CDS YP_004738943.1 340620490 10976929 5234041..5235582 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain, here a PglZ domain, a member of Alkaline phosphatase clan; Localized in the cytoplasm; Family membership; two-component system-response regulator 5235582 10976929 zobellia_4529 Zobellia galactanivorans two-component system-response regulator YP_004738943.1 5234041 D 63186 CDS YP_004738944.1 340620491 10976930 5235595..5236008 1 NC_015844.1 This protein belongs to the UPF0079 family. This group consists of bacterial proteins, which contain a P-loop. They are probably essential to bacteria as members are found in all genomes so far sequenced and no equivalent genes have been found in the archaea and eukaryotes. These proteins adopt a nucleotide-binding fold with a four-stranded parallel beta-sheet flanked by antiparallel beta-strands on each side. The topology of the beta-sheet is unique among P-loop proteins and has features of different families of enzymes. ADP has been shown to bind to the P-loop in the presence of Mg2+ and ATPase activity has been confirmed by kinetic measurements. Localized in the cytoplasm.; Specificity unclear; ATPase 5236008 10976930 zobellia_4530 Zobellia galactanivorans ATPase YP_004738944.1 5235595 D 63186 CDS YP_004738945.1 340620492 10976932 5236175..5236423 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 26 and 27; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5236423 10976932 zobellia_4531 Zobellia galactanivorans hypothetical protein YP_004738945.1 5236175 D 63186 CDS YP_004738946.1 340620493 10976933 5236522..5237199 1 NC_015844.1 Contains four transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5237199 10976933 zobellia_4532 Zobellia galactanivorans membrane protein YP_004738946.1 5236522 D 63186 CDS YP_004738947.1 340620494 10976934 5237305..5238504 1 NC_015844.1 Alanine dehydrogenase is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid. It converts L-alanine to pyruvate and ammoniac. It forms a homohexamer and binds one NAD+ per subunit as cofactor; Localized in the cytoplasm; High confidence in function and specificity; alanine dehydrogenase 5238504 aldA 10976934 aldA Zobellia galactanivorans alanine dehydrogenase YP_004738947.1 5237305 D 63186 CDS YP_004738948.1 340620495 10977491 5238650..5239033 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5239033 10977491 zobellia_4534 Zobellia galactanivorans membrane protein YP_004738948.1 5238650 D 63186 CDS YP_004738949.1 340620496 10976935 complement(5239073..5240239) 1 NC_015844.1 CarD is involved in carbapenem antibiotic biosynthesis, but its exact function is unknown. Belongs to the proline dehydrogenase family and likely binds a FAD as a cofactor. Localized in the cytoplasm.; Function unclear; carbapenem antibiotics biosynthesis protein carD 5240239 10976935 zobellia_4535 Zobellia galactanivorans carbapenem antibiotics biosynthesis protein carD YP_004738949.1 5239073 R 63186 CDS YP_004738950.1 340620497 10976936 5240370..5241434 1 NC_015844.1 3-Dehydroquinate synthase is involved in the biosynthesis of aromatic amino acids. It catalyzes the second step of the shikimate pathway, the formation of dehydroquinate and orthophosphate from 3-deoxy-D-arabino heptulosonic 7 phosphate. It forms a monomer and binds NAD and divalent metal cation as cofactors. Localized in the cytoplasm.; High confidence in function and specificity; 3-dehydroquinate synthase 5241434 aroB2 10976936 aroB2 Zobellia galactanivorans 3-dehydroquinate synthase YP_004738950.1 5240370 D 63186 CDS YP_004738951.1 340620498 10977545 5241566..5241892 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 5241892 10977545 zobellia_4537 Zobellia galactanivorans hypothetical protein YP_004738951.1 5241566 D 63186 CDS YP_004738952.1 340620499 10976937 complement(5241912..5242430) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5242430 10976937 zobellia_4538 Zobellia galactanivorans hypothetical protein YP_004738952.1 5241912 R 63186 CDS YP_004738953.1 340620500 10976938 complement(5242503..5242982) 1 NC_015844.1 The transcriptional regulator AsnC is the activator of the asnA gene involved in the asparagine synthesis and is a autogenous regulator of its own transcription; Contains a N-terminal AsnC/Lrp-type HTH domain; Localized in the cytoplasm; High confidence in function and specificity; transcriptional regulator AsnC 5242982 asnC3 10976938 asnC3 Zobellia galactanivorans transcriptional regulator AsnC YP_004738953.1 5242503 R 63186 CDS YP_004738954.1 340620501 10977561 complement(5243098..5244207) 1 NC_015844.1 Peptidase family M14 contains mainly metallocarboxypeptidases. The single catalytic zinc ion is tetrahedrally coordinated by two histidines and a glutamate, as well as a water molecule. One of the histidines and the glutamate occur in the motif His-Xaa-Xaa-Glu; Localized in the cytoplasm; Specificity unclear; metallopeptidase 4 5244207 10977561 zobellia_4540 Zobellia galactanivorans metallopeptidase 4 YP_004738954.1 5243098 R 63186 CDS YP_004738955.1 340620502 10976940 5244499..5244882 1 NC_015844.1 Transcriptional regulator with a helix-turn-helix DNA-binding motif located in the N-terminal part. The C-terminal part may contain an oligomerization domain; Belongs to the Cro/C1-type transcriptional regulator family; Localized in the cytoplasm; Family membership; Cro/C1-type transcriptional regulator 5244882 10976940 zobellia_4541 Zobellia galactanivorans Cro/C1-type transcriptional regulator YP_004738955.1 5244499 D 63186 CDS YP_004738956.1 340620503 10976941 5244851..5245285 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5245285 10976941 zobellia_4542 Zobellia galactanivorans membrane protein YP_004738956.1 5244851 D 63186 CDS YP_004738957.1 340620504 10976942 complement(5245355..5245498) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5245498 10976942 zobellia_4543 Zobellia galactanivorans hypothetical protein YP_004738957.1 5245355 R 63186 CDS YP_004738958.1 340620505 10976943 complement(5245639..5246595) 1 NC_015844.1 Conserved protein belonging to the Fatty acid hydroxylase family which includes fatty acid and carotene hydroxylases and sterol desaturases; Contains three transmembrane helices; Localized in the cytoplasmic membrane.; Family membership; fatty acid hydroxylase family protein 5246595 10976943 zobellia_4544 Zobellia galactanivorans fatty acid hydroxylase family protein YP_004738958.1 5245639 R 63186 CDS YP_004738959.1 340620506 10976944 complement(5246852..5249587) 1 NC_015844.1 DNA topoisomerase IV is essential for chromosome segregation. In an ATP-dependent manner, it acts to relax positive supercoils in DNA and performs the decatenation events required during the replication of a circular DNA molecule; DNA topoisomerase IV is composed of two subunits parC and parE; Belongs to the type-II topoisomerase family, type-IIA subfamily; Localized in the cytoplasm; High confidence in function and specificity; DNA topoisomerase IV subunit A 5249587 parC 10976944 parC Zobellia galactanivorans DNA topoisomerase IV subunit A YP_004738959.1 5246852 R 63186 CDS YP_004738960.1 340620507 10978303 complement(5249613..5251475) 1 NC_015844.1 DNA topoisomerase IV is essential for chromosome segregation. In an ATP-dependent manner, It acts to relax positive supercoils in DNA and performs the decatenation events required during the replication of a circular DNA molecule; DNA topoisomerase IV is composed of two subunits parC and parE; Belongs to the type-II topoisomerase family, type-IIA subfamily; Localized in the cytoplasm; High confidence in function and specificity; DNA topoisomerase IV subunit B 5251475 parE 10978303 parE Zobellia galactanivorans DNA topoisomerase IV subunit B YP_004738960.1 5249613 R 63186 CDS YP_004738961.1 340620508 10978304 5251735..5253012 1 NC_015844.1 Carboxypeptidase catalyzes the hydrolysis of C-terminal amino acid residues from oligopeptides or polypeptides. This enzyme can release basic, acidic, aromatic, and, to a lesser extent, aliphatic amino acids. Belongs to the family M20 of the metallopeptidase. CpsA binds two co-catalytic zinc ions, which are coordinated by five conserved residues (His/Asp, Asp, Glu, Glu/Asp, His). The zinc ions stabilize the tetrahedral intermediate and activate the catalytic water molecule. Features a signal peptide cleaved between the residues 20 and 21. Localized in the periplasm.; High confidence in function and specificity; carboxypeptidase 5253012 cpsA2 10978304 cpsA2 Zobellia galactanivorans carboxypeptidase YP_004738961.1 5251735 D 63186 CDS YP_004738962.1 340620509 10977673 5253062..5254636 1 NC_015844.1 Conserved protein Localized in the cytoplasmic membrane; Conserved hypothetical protein; FMN / Fe-S cluster binding protein 5254636 10977673 zobellia_4548 Zobellia galactanivorans FMN / Fe-S cluster binding protein YP_004738962.1 5253062 D 63186 CDS YP_004738963.1 340620510 10976945 5254705..5255475 1 NC_015844.1 Conserved protein containing a C-terminal OmpA-like domain. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space and/or in the outer membrane; Family membership; OmpA-like periplasmic protein 5255475 10976945 zobellia_4549 Zobellia galactanivorans OmpA-like periplasmic protein YP_004738963.1 5254705 D 63186 CDS YP_004738964.1 340620511 10976946 5255551..5256072 1 NC_015844.1 Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5256072 10976946 zobellia_4550 Zobellia galactanivorans membrane protein YP_004738964.1 5255551 D 63186 CDS YP_004738965.1 340620512 10976948 complement(5256139..5257059) 1 NC_015844.1 This protein belongs to a phospholipase family including the Patatin, a lipid acyl hydrolase, catalysing the cleavage of fatty acids from membrane lipids. Localized in the cytoplasm.; Specificity unclear; phospholipase, Patatin family 5257059 10976948 zobellia_4551 Zobellia galactanivorans phospholipase, Patatin family YP_004738965.1 5256139 R 63186 CDS YP_004738966.1 340620513 10976949 complement(5257063..5259123) 1 NC_015844.1 Aminopeptidase catalyzes the hydrolysis of N-terminal amino-acid residues from oligopeptides or polypeptides. This enzyme belongs to the family M1 of the peptidases. A catalytic zinc ion is bound by two histidines and a glutamate. The histidines are within an 'HEXXH' motif on one long helix with the glutamate on another antiparallel helix. The catalytic mechanism is believed to involve activation of a water molecule by the zinc ion. The glutamate of the HEXXH motif is known to be important for catalysis and a tyrosine may also be involved. Features a signal peptide cleaved between the residues 18 and 19. Localized in the periplasm.; Specificity unclear; aminopeptidase 5259123 10976949 zobellia_4552 Zobellia galactanivorans aminopeptidase YP_004738966.1 5257063 R 63186 CDS YP_004738967.1 340620514 10976950 5259202..5261307 1 NC_015844.1 RecG plays a critical role in recombination and DNA repair. It helps process Holliday junction intermediates to mature products by catalyzing branch migration. Acts as a DNA helicase with a 3' to 5' polarity. RecG unwind branched duplex DNA (Y-DNA). Has a role in constitutive stable DNA replication (csdR) and R-loop formation; Belongs to the DEAD and DEAH helicase family; Localized in the cytoplasm; High confidence in function and specificity; ATP-dependent DNA helicase RecG 5261307 recG 10976950 recG Zobellia galactanivorans ATP-dependent DNA helicase RecG YP_004738967.1 5259202 D 63186 CDS YP_004738968.1 340620515 10978443 5261362..5261487 1 NC_015844.1 Hypothetical protein; hypothetical protein 5261487 10978443 zobellia_4554 Zobellia galactanivorans hypothetical protein YP_004738968.1 5261362 D 63186 CDS YP_004738969.1 340620516 10976951 5261528..5262298 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the cytoplasmic membrane; Conserved hypothetical protein; lipoprotein 5262298 10976951 zobellia_4555 Zobellia galactanivorans lipoprotein YP_004738969.1 5261528 D 63186 CDS YP_004738970.1 340620517 10976952 5262655..5264070 1 NC_015844.1 3-Isopropylmalate dehydratase catalyzes the second step the L-leucine biosynthesis pathway. It converts (2R, 3S)-3-isopropylmalate into 3-hydroxy-4-methyl-3-carboxypentanoate, via the formation of (2S)-2-isopropylmaleate. Two successive isomerizations are catalyzed: (i) (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmaleate + H2O and (ii)(2S)-2-isopropylmaleate + H2O = 3-hydroxy-4-methyl-3-carboxypentanoate. 3-Isopropylmalate dehydratase. 3-Isopropylmalate dehydratase is a heterodimer of LeuC and LeuD and binds one 4Fe-4S cluster per subunit. LeuC belongs to the aconitase family. Localized in the cytoplasm.; High confidence in function and specificity; 3-Isopropylmalate dehydratase, large subunit 5264070 leuC 10976952 leuC Zobellia galactanivorans 3-Isopropylmalate dehydratase, large subunit YP_004738970.1 5262655 D 63186 CDS YP_004738971.1 340620518 10978084 5264110..5264706 1 NC_015844.1 3-Isopropylmalate dehydratase catalyzes the second step the L-leucine biosynthesis pathway. It converts (2R, 3S)-3-isopropylmalate into 3-hydroxy-4-methyl-3-carboxypentanoate, via the formation of (2S)-2-isopropylmaleate. Two successive isomerizations are catalyzed: (i) (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmaleate + H2O and (ii)(2S)-2-isopropylmaleate + H2O = 3-hydroxy-4-methyl-3-carboxypentanoate. 3-Isopropylmalate dehydratase. 3-Isopropylmalate dehydratase is a heterodimer of LeuC and LeuD. LeuD belongs to the aconitase C-terminal domain family. Localized in the cytoplasm.; High confidence in function and specificity; 3-Isopropylmalate dehydratase, small subunit 5264706 leuD 10978084 leuD Zobellia galactanivorans 3-Isopropylmalate dehydratase, small subunit YP_004738971.1 5264110 D 63186 CDS YP_004738972.1 340620519 10978085 5264838..5266355 1 NC_015844.1 2-Isopropylmalate synthase catalyzes the first step in the L-leucine biosynthesis pathway. LeuA condensates the acetyl group of acetyl-CoA with 3-methyl-2- oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). Its features a N-terminal catalytic HMGL-like domain and a C-terminal LeuA-dimerization domain. LeuA forms a homotetramer. Localized in the cytoplasm.; High confidence in function and specificity; 2-Isopropylmalate synthase 5266355 leuA1 10978085 leuA1 Zobellia galactanivorans 2-Isopropylmalate synthase YP_004738972.1 5264838 D 63186 CDS YP_004738973.1 340620520 10978080 5266567..5267622 1 NC_015844.1 3-Isopropylmalate dehydrogenase catalyzes the third step in the L-leucine biosynthesis pathway. LeuB catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. LeuB forms a homodimer and binds one NAD+ and one Mg2+ or Mn2+ ion by subunit. Localized in the cytoplasm.; High confidence in function and specificity; 3-Isopropylmalate dehydrogenase 5267622 LeuB1 10978080 LeuB1 Zobellia galactanivorans 3-Isopropylmalate dehydrogenase YP_004738973.1 5266567 D 63186 CDS YP_004738974.1 340620521 10978082 complement(5267780..5268355) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5268355 10978082 zobellia_4560 Zobellia galactanivorans hypothetical protein YP_004738974.1 5267780 R 63186 CDS YP_004738975.1 340620522 10976954 complement(5268658..5268891) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5268891 10976954 zobellia_4561 Zobellia galactanivorans hypothetical protein YP_004738975.1 5268658 R 63186 CDS YP_004738976.1 340620523 10976955 complement(5269136..5269972) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 5269972 10976955 zobellia_4562 Zobellia galactanivorans AraC family transcriptional regulator YP_004738976.1 5269136 R 63186 CDS YP_004738977.1 340620524 10976956 complement(5270208..5271059) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 5271059 10976956 zobellia_4563 Zobellia galactanivorans AraC family transcriptional regulator YP_004738977.1 5270208 R 63186 CDS YP_004738978.1 340620525 10976957 complement(5271355..5272554) 1 NC_015844.1 The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients; Contains 12 transmembrane segments; Localized in the cytoplasmic membrane; Family membership; major facilitator family transporter 5272554 10976957 zobellia_4564 Zobellia galactanivorans major facilitator family transporter YP_004738978.1 5271355 R 63186 CDS YP_004738979.1 340620526 10976958 complement(5272833..5274413) 1 NC_015844.1 The NADP-dependent glyceraldehyde-3-phosphate dehydrogenase is important as a means of generating NADPH for biosynthetic reactions. It converts the D-glyceraldehyde 3-phosphate to 3-phospho-D-glycerate; Forms a homotetramer and binds a NADP+ per subunit as cofactors; Localized in the cytoplasm; High confidence in function and specificity; glyceraldehyde 3-phosphate dehydrogenase 5274413 gapN 10976958 gapN Zobellia galactanivorans glyceraldehyde 3-phosphate dehydrogenase YP_004738979.1 5272833 R 63186 CDS YP_004738980.1 340620527 10977881 complement(5274552..5275802) 1 NC_015844.1 Involved in the first step in the pathway converting threonine into isoleucine, it catalyzes the formation of alpha-ketobutyrate from threonine in a two- step reaction. The first step is a dehydration of threonine, followed by rehydration and liberation of ammonia; Uses the pyridoxal phosphate (vitamin B6) as prosthetic group; Belongs to the serine/threonine dehydratase family; Localized in the cytoplasm; High confidence in function and specificity; threonine dehydratase 5275802 ilvA 10977881 ilvA Zobellia galactanivorans threonine dehydratase YP_004738980.1 5274552 R 63186 CDS YP_004738981.1 340620528 10978029 complement(5275880..5277355) 1 NC_015844.1 Ketol-acid reductoisomerase catalyses the conversion of acetohydroxy acids into dihydroxy valerates. This reaction is the second in the synthetic pathway of the essential branched side chain amino acids valine and isoleucine. IlvC uses NADP(H) as a cofactor; Localized in the cytoplasm; High confidence in function and specificity; Ketol-acid reductoisomerase 5277355 ilvC 10978029 ilvC Zobellia galactanivorans Ketol-acid reductoisomerase YP_004738981.1 5275880 R 63186 CDS YP_004738982.1 340620529 10978031 complement(5277451..5277981) 1 NC_015844.1 Acetolactate synthase is a complex of a large catalytic chain and a smaller regulatory chain associated in an alpha2/beta2 heterotetramer. It catalyzes the first step of the isoleucine and valine biosynthesic pathways. The regulatory subunit, IlvH, features an ACT domain. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration; Localized in the cytoplasm; High confidence in function and specificity; acetolactate synthase small subunit 5277981 ilvH 10978031 ilvH Zobellia galactanivorans acetolactate synthase small subunit YP_004738982.1 5277451 R 63186 CDS YP_004738983.1 340620530 10978035 complement(5278332..5278913) 1 NC_015844.1 O-Methyltransferase binding S-adenosylmethionine as a cofactor. Its substrate specificity is unknown; Localized in the cytoplasm; Specificity unclear; S-adenosylmethionine-dependent O-methyltransferase 5278913 10978035 zobellia_4569 Zobellia galactanivorans S-adenosylmethionine-dependent O-methyltransferase YP_004738983.1 5278332 R 63186 CDS YP_004738984.1 340620531 10976959 complement(5278942..5280675) 1 NC_015844.1 Acetolactate synthase is a complex of a large catalytic chain and a small regulatory chain associated in an alpha2/beta2 heterotetramer. It catalyzes the first step of the isoleucine and valine biosynthesic pathways. The catalytic subunit, IlvB, is a thiamine pyrophosphate-dependent enzyme. It also binds one magnesium ion and one FAD per subunit, although the role of this cofactor is not clear considering that the reaction does not involve redox chemistry; Localized in the cytoplasm; High confidence in function and specificity; acetolactate synthase, large subunit 5280675 ilvB 10976959 ilvB Zobellia galactanivorans acetolactate synthase, large subunit YP_004738984.1 5278942 R 63186 CDS YP_004738985.1 340620532 10978030 complement(5280758..5282434) 1 NC_015844.1 Dihydroxy-acid dehydratase catalyzes the fourth step in the biosynthesis of isoleucine and valine, the dehydratation of 2,3-dihydroxy-isovaleic acid into alpha-ketoisovaleric acid; Binds a 4Fe-4S cluster; Localized in the cytoplasm; High confidence in function and specificity; dihydroxy-acid dehydratase 5282434 ilvD1 10978030 ilvD1 Zobellia galactanivorans dihydroxy-acid dehydratase YP_004738985.1 5280758 R 63186 CDS YP_004738986.1 340620533 10978032 complement(5282860..5283699) 1 NC_015844.1 Protein that shows some similarities with the uncharacterized YbgK protein from Escherichia coli K12. YbgK and YbgJ Probably are involved in a common metabolism; Contains a Allophanate hydrolase subunit 2 domain; Localized in the cytoplasm; hypothetical protein 5283699 ybgK 10978032 ybgK Zobellia galactanivorans hypothetical protein YP_004738986.1 5282860 R 63186 CDS YP_004738987.1 340620534 10978775 complement(5283692..5284429) 1 NC_015844.1 Protein that shows some similarities with the uncharacterized YbgJ protein from Escherichia coli K12. YbgJ and YbgK Probably are involved in a common metabolism; Contains a Allophanate hydrolase subunit 1 domain; Localized in the cytoplasm; hypothetical protein 5284429 ybgJ 10978775 ybgJ Zobellia galactanivorans hypothetical protein YP_004738987.1 5283692 R 63186 CDS YP_004738988.1 340620535 10978774 complement(5284426..5285169) 1 NC_015844.1 Protein belonging to the LamB family (UPF0271). The exact molecular function of the proteins in this family is unknown; Localized in the cytoplasm; Function unclear; LamB family protein 5285169 10978774 zobellia_4574 Zobellia galactanivorans LamB family protein YP_004738988.1 5284426 R 63186 CDS YP_004738989.1 340620536 10976961 5285453..5285896 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5285896 10976961 zobellia_4575 Zobellia galactanivorans hypothetical protein YP_004738989.1 5285453 D 63186 CDS YP_004738990.1 340620537 10976962 5285914..5286477 1 NC_015844.1 Contains six transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5286477 10976962 zobellia_4576 Zobellia galactanivorans membrane protein YP_004738990.1 5285914 D 63186 CDS YP_004738991.1 340620538 10976963 5287053..5287178 1 NC_015844.1 Hypothetical protein; hypothetical protein 5287178 10976963 zobellia_4577 Zobellia galactanivorans hypothetical protein YP_004738991.1 5287053 D 63186 CDS YP_004738992.1 340620539 10976964 complement(5287340..5288047) 1 NC_015844.1 Protein displaying similarity with the C-terminal region of Mg chelatase subunit ChlI; Localized in the cytoplasm; Function unclear; Mg chelatase family protein 5288047 10976964 zobellia_4578 Zobellia galactanivorans Mg chelatase family protein YP_004738992.1 5287340 R 63186 CDS YP_004738993.1 340620540 10976965 5288290..5288550 1 NC_015844.1 Contains two transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5288550 10976965 zobellia_4579 Zobellia galactanivorans hypothetical protein YP_004738993.1 5288290 D 63186 CDS YP_004738994.1 340620541 10976966 5288556..5288819 1 NC_015844.1 Hypothetical protein; hypothetical protein 5288819 10976966 zobellia_4580 Zobellia galactanivorans hypothetical protein YP_004738994.1 5288556 D 63186 CDS YP_004738995.1 340620542 10976968 5289156..5290766 1 NC_015844.1 Serine recombinases perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and serine recombinase; Contains an N-terminal catalytic and dimerization domain (with the conserved serine residue), a central conserved domain usually associated with recombinases and a C-terminal helix-turn-helix DNA-binding domain; Belongs to the site-specific Serine recombinase family; Localized in the cytoplasm; High confidence in function and specificity; Large serine recombinase 5290766 10976968 zobellia_4581 Zobellia galactanivorans Large serine recombinase YP_004738995.1 5289156 D 63186 CDS YP_004738996.1 340620543 10976969 5290829..5291776 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5291776 10976969 zobellia_4582 Zobellia galactanivorans hypothetical protein YP_004738996.1 5290829 D 63186 CDS YP_004738997.1 340620544 10976970 5291781..5292353 1 NC_015844.1 Proteins in the PIN domain family are Localized in the cytoplasm; Function unclear; PIN-like protein 5292353 10976970 zobellia_4583 Zobellia galactanivorans PIN-like protein YP_004738997.1 5291781 D 63186 CDS YP_004738998.1 340620545 10976971 5292596..5293087 1 NC_015844.1 The Genetic Element Protein A is part of a Bacteriophage or a conjugative transposon. Its exact function is unknown; Localized in the cytoplasm; Function unclear; Genetic Element protein A 5293087 gepA 10976971 gepA Zobellia galactanivorans Genetic Element protein A YP_004738998.1 5292596 D 63186 CDS YP_004738999.1 340620546 10977891 5293093..5293425 1 NC_015844.1 Contains one transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5293425 10977891 zobellia_4585 Zobellia galactanivorans hypothetical protein YP_004738999.1 5293093 D 63186 CDS YP_004739000.1 340620547 10976972 5293434..5293574 1 NC_015844.1 Hypothetical protein; hypothetical protein 5293574 10976972 zobellia_4586 Zobellia galactanivorans hypothetical protein YP_004739000.1 5293434 D 63186 CDS YP_004739001.1 340620549 10976973 complement(5293850..5293993) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5293993 10976973 zobellia_4588 Zobellia galactanivorans hypothetical protein YP_004739001.1 5293850 R 63186 CDS YP_004739002.1 340620548 10976975 5293984..5294196 1 NC_015844.1 Contains a transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5294196 10976975 zobellia_4587 Zobellia galactanivorans hypothetical protein YP_004739002.1 5293984 D 63186 CDS YP_004739003.1 340620550 10976974 5294389..5294526 1 NC_015844.1 Hypothetical protein; hypothetical protein 5294526 10976974 zobellia_4589 Zobellia galactanivorans hypothetical protein YP_004739003.1 5294389 D 63186 CDS YP_004739004.1 340620551 10976976 5294659..5295252 1 NC_015844.1 Transposon resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products. It contains an N-terminal catalytic and dimerization domain that contains a conserved serine residue involved in the transient covalent attachment to DNA, and a C-terminal helix-turn-helix DNA-binding domain; Belongs to the site-specific Serine Recombinase family, Resolvase and Invertase subfamily; Localized in the cytoplasm; High confidence in function and specificity; transposon resolvase 5295252 tnpR 10976976 tnpR Zobellia galactanivorans transposon resolvase YP_004739004.1 5294659 D 63186 CDS YP_004739005.1 340620552 10978666 5295413..5295700 1 NC_015844.1 Hypothetical protein; hypothetical protein 5295700 10978666 zobellia_4591 Zobellia galactanivorans hypothetical protein YP_004739005.1 5295413 D 63186 CDS YP_004739006.1 340620553 10976978 5295700..5297166 1 NC_015844.1 Protein containing a C-terminal Poxvirus D5 protein-like found at the C terminus of phage P4 alpha protein and related proteins. This domain could correspond the ori DNA recognition site; Localized in the cytoplasm; Family membership; Poxvirus D5-like protein 5297166 10976978 zobellia_4592 Zobellia galactanivorans Poxvirus D5-like protein YP_004739006.1 5295700 D 63186 CDS YP_004739007.1 340620554 10976979 5297151..5298014 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5298014 10976979 zobellia_4593 Zobellia galactanivorans hypothetical protein YP_004739007.1 5297151 D 63186 CDS YP_004739008.1 340620555 10976980 5298011..5298523 1 NC_015844.1 Putatively localized in the cytoplasm; hypothetical protein 5298523 10976980 zobellia_4594 Zobellia galactanivorans hypothetical protein YP_004739008.1 5298011 D 63186 CDS YP_004739009.1 340620556 10976981 5298520..5299053 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5299053 10976981 zobellia_4595 Zobellia galactanivorans hypothetical protein YP_004739009.1 5298520 D 63186 CDS YP_004739010.1 340620557 10976982 5299105..5299224 1 NC_015844.1 Hypothetical protein; hypothetical protein 5299224 10976982 zobellia_4596 Zobellia galactanivorans hypothetical protein YP_004739010.1 5299105 D 63186 CDS YP_004739011.1 340620558 10976983 complement(5299221..5299487) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5299487 10976983 zobellia_4597 Zobellia galactanivorans hypothetical protein YP_004739011.1 5299221 R 63186 CDS YP_004739012.1 340620559 10976984 complement(5299523..5300233) 1 NC_015844.1 Conserved hypothetical protein belonging to the DUF159 family; Localized in the cytoplasm; hypothetical protein 5300233 10976984 zobellia_4598 Zobellia galactanivorans hypothetical protein YP_004739012.1 5299523 R 63186 CDS YP_004739013.1 340620560 10976985 complement(5300282..5301130) 1 NC_015844.1 ComM is induced during competence development. Not needed for DNA uptake. May be involved in a recombination step; Belongs to the Mg-chelatase subunits D/I family, ComM subfamily; Localized in the cytoplasm; High confidence in function and specificity; competence protein comM 5301130 comM 10976985 comM Zobellia galactanivorans competence protein comM YP_004739013.1 5300282 R 63186 CDS YP_004739014.1 340620561 10977667 complement(5301182..5303581) 1 NC_015844.1 Acyl-homoserine lactone acylase catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid; Belongs to the family 45 of the serine peptidases (45); Signal peptide cleaved between the residues 26 and 27; Localized in the periplasmic space; High confidence in function and specificity; acyl-homoserine lactone acylase 5303581 quiP 10977667 quiP Zobellia galactanivorans acyl-homoserine lactone acylase YP_004739014.1 5301182 R 63186 CDS YP_004739015.1 340620562 10978429 complement(5304047..5306014) 1 NC_015844.1 DsbD, also known as protein-disulfide reductase, is required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps; Uses NAD(P) as cofactor; Contains eight transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; thiol:disulfide interchange protein 5306014 dsbD 10978429 dsbD Zobellia galactanivorans thiol:disulfide interchange protein YP_004739015.1 5304047 R 63186 CDS YP_004739016.1 340620563 10977766 complement(5306011..5307318) 1 NC_015844.1 TilS ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding; Localized in the cytoplasm; High confidence in function and specificity; tRNA(Ile)-lysidine synthase 5307318 tilS 10977766 tilS Zobellia galactanivorans tRNA(Ile)-lysidine synthase YP_004739016.1 5306011 R 63186 CDS YP_004739017.1 340620564 10978663 complement(5307380..5308678) 1 NC_015844.1 Enzyme that contains a C-terminal chorismate binding domain and belonging to the anthranilate synthase component I family; Localized in the cytoplasm; Family membership; anthranilate synthase component I-like protein 5308678 10978663 zobellia_4603 Zobellia galactanivorans anthranilate synthase component I-like protein YP_004739017.1 5307380 R 63186 CDS YP_004739018.1 340620566 10976987 complement(5308689..5309222) 1 NC_015844.1 Flavoprotein belonging to the NADPH-dependent FMN reductase family. Its specificity is unclear; Localized in the cytoplasm; Specificity unclear; hypothetical protein 5309222 10976987 zobellia_4605 Zobellia galactanivorans hypothetical protein YP_004739018.1 5308689 R 63186 CDS YP_004739019.1 340620565 10976989 5309204..5309428 1 NC_015844.1 Hypothetical protein; hypothetical protein 5309428 10976989 zobellia_4604 Zobellia galactanivorans hypothetical protein YP_004739019.1 5309204 D 63186 CDS YP_004739020.1 340620567 10976988 5309444..5310628 1 NC_015844.1 Contains eight transmembrane helice; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5310628 10976988 zobellia_4606 Zobellia galactanivorans membrane protein YP_004739020.1 5309444 D 63186 CDS YP_004739021.1 340620568 10976990 complement(5310712..5312118) 1 NC_015844.1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2, linking glycolysis to the tricarboxylic acid cycle. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). PdhD is the E3 component. It catalyzes the oxidation of dihydrolipoamide to lipoamide. PdhD is a homodimer which binds 1 NADP and 1 FAD per subunit; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family; Localized in the cytoplasm; High confidence in function and specificity; dihydrolipoyl dehydrogenase, E3 component 5312118 pdhD 10976990 pdhD Zobellia galactanivorans dihydrolipoyl dehydrogenase, E3 component YP_004739021.1 5310712 R 63186 CDS YP_004739022.1 340620569 10978318 5312250..5313728 1 NC_015844.1 NhaC is a Na+/H+ antiporter involved in pH homeostasis and sodium extrusion; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; Na+/H+ antiporter NhaC 5313728 nhaC 10978318 nhaC Zobellia galactanivorans Na+/H+ antiporter NhaC YP_004739022.1 5312250 D 63186 CDS YP_004739023.1 340620570 10978250 5313978..5314622 1 NC_015844.1 Peroxiredoxins are thiol peroxidase involved in redox regulation of the cell. Can reduce H(2)O(2), short chain organic, fatty acid, and phospholipid hydroperoxides. The peroxidase reaction comprises two steps centered around a redox-active cysteine called the peroxidatic cysteine. It oxidized the peroxide substrate to S-hydroxycysteine (a sulfenic acid). The second step is the regeneration of cysteine from S-hydroxycysteine. This regeneration is due to thiol-containing reductants such as thioredoxin; Localized in the cytoplasm; Specificity unclear; peroxiredoxin 5314622 10978250 zobellia_4609 Zobellia galactanivorans peroxiredoxin YP_004739023.1 5313978 D 63186 CDS YP_004739024.1 340620571 10976991 5314727..5315041 1 NC_015844.1 Thioredoxin is a small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase; Localized in the cytoplasm; High confidence in function and specificity; thioredoxin 5315041 trxA 10976991 trxA Zobellia galactanivorans thioredoxin YP_004739024.1 5314727 D 63186 CDS YP_004739025.1 340620572 10978708 5315022..5315279 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 5315279 10978708 zobellia_4611 Zobellia galactanivorans hypothetical protein YP_004739025.1 5315022 D 63186 CDS YP_004739026.1 340620573 10976993 5315469..5315975 1 NC_015844.1 Thiol peroxidase has an antioxidant activity by removing peroxides or H(2)O(2). Localized in the cytoplasm.; High confidence in function and specificity; thiol peroxidase 5315975 tpx 10976993 tpx Zobellia galactanivorans thiol peroxidase YP_004739026.1 5315469 D 63186 CDS YP_004739027.1 340620574 10978676 5315968..5316336 1 NC_015844.1 Diacylglycerol kinase recycles diacylglycerol produced during the turnover of membrane phospholipids. May play a role in adaptability to environmental stress conditions such as acid tolerance, elevated temperatures and high osmolarity. Features two transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; Diacylglycerol kinase 5316336 dgkA 10978676 dgkA Zobellia galactanivorans Diacylglycerol kinase YP_004739027.1 5315968 D 63186 CDS YP_004739028.1 340620575 10977734 5316390..5318339 1 NC_015844.1 Protein that could belong to the alkaline phosphatase superfamily; Contains five N-terminal transmembrane segments; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5318339 10977734 zobellia_4614 Zobellia galactanivorans hypothetical protein YP_004739028.1 5316390 D 63186 CDS YP_004739029.1 340620576 10976994 5318449..5320842 1 NC_015844.1 FtsK is a DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind it. It forms a hexamer. Features four transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; DNA translocase FtsK 5320842 ftsK 10976994 ftsK Zobellia galactanivorans DNA translocase FtsK YP_004739029.1 5318449 D 63186 CDS YP_004739030.1 340620577 10977849 5320869..5321513 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5321513 10977849 zobellia_4616 Zobellia galactanivorans periplasmic protein YP_004739030.1 5320869 D 63186 CDS YP_004739031.1 340620578 10976995 5321593..5323083 1 NC_015844.1 Contains five transmembrane helices; Belongs to the predicted permease YjgP/YjgQ family; Localized in the cytoplasmic membrane; Family membership; membrane protein 5323083 10976995 zobellia_4617 Zobellia galactanivorans membrane protein YP_004739031.1 5321593 D 63186 CDS YP_004739032.1 340620579 10976996 5323080..5324222 1 NC_015844.1 Riboflavin biosynthesis protein RibAB is a bifunctional enzyme with a N-terminal 3,4-dihydroxy-2-butanone 4-phosphate synthase domain and a C-terminal GTP cyclohydrolase II domain. The former enzymatic activity synthesized 3,4-Dihydroxy-2-butanone 4-phosphate from ribulose 5-phosphate and serves as the biosynthetic precursor for the xylene ring of riboflavin. GTP cyclohydrolase II catalyzes the first step in the biosynthesis of riboflavin. The enzyme converts GTP and water to formate, 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine and pyrophosphate, and requires magnesium as a cofactor; Localized in the cytoplasm; High confidence in function and specificity; riboflavin biosynthesis protein RibAB 5324222 ribAB 10976996 ribAB Zobellia galactanivorans riboflavin biosynthesis protein RibAB YP_004739032.1 5323080 D 63186 CDS YP_004739033.1 340620580 10978459 complement(5324242..5328276) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 5328276 10978459 zobellia_4619 Zobellia galactanivorans one-component system sensor protein YP_004739033.1 5324242 R 63186 CDS YP_004739034.1 340620581 10976997 complement(5328339..5330651) 1 NC_015844.1 Belongs to the family 92 of glycoside hydrolases (GH92); Possibly involved in the mannane degradation or putatively involved in the glycoprotein biosynthesis; Signal peptide of lipoprotein cleaved between the residues 22 and 23; Putatively localized in the outer membrane; High confidence in function and specificity; alpha-1,2-mannosidase 5330651 manA 10976997 manA Zobellia galactanivorans alpha-1,2-mannosidase YP_004739034.1 5328339 R 63186 CDS YP_004739035.1 340620582 10978122 complement(5330665..5332716) 1 NC_015844.1 Glycoside hydrolases hydrolyse the glycosidic bond between two or more carbohydrates or between a carbohydrate and a non-carbohydrate moiety; Belongs to the family 115 of the glycoside hydrolases; Signal peptide cleaved between the residues 26 and 27; Putatively localized in the periplasmic space; Conserved hypothetical protein; glycoside hydrolase 5332716 10978122 zobellia_4621 Zobellia galactanivorans glycoside hydrolase YP_004739035.1 5330665 R 63186 CDS YP_004739036.1 340620583 10976998 complement(5332814..5334475) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 23 and 24; Putatively localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 5334475 10976998 zobellia_4622 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004739036.1 5332814 R 63186 CDS YP_004739037.1 340620584 10976999 complement(5334494..5337568) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (23-97) and the Plug module (113-236) acting as a channel gate; The signal peptide is cleaved between the residues 21 and 22; Family membership; TonB-dependent Receptor 5337568 10976999 zobellia_4623 Zobellia galactanivorans TonB-dependent Receptor YP_004739037.1 5334494 R 63186 CDS YP_004739038.1 340620585 10977000 complement(5337947..5338732) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5338732 10977000 zobellia_4624 Zobellia galactanivorans periplasmic protein YP_004739038.1 5337947 R 63186 CDS YP_004739039.1 340620586 10977001 complement(5338821..5340011) 1 NC_015844.1 Protein belonging to the DegT/DnrJ/EryC1/StrS aminotransferase family, which is included in the pyridoxal-phosphate (PLP)-dependent aminotransferase superfamily; Localized in the cytoplasm; Specificity unclear; PLP-dependent aminotransferase 5340011 10977001 zobellia_4625 Zobellia galactanivorans PLP-dependent aminotransferase YP_004739039.1 5338821 R 63186 CDS YP_004739040.1 340620587 10977002 complement(5340053..5340691) 1 NC_015844.1 Also called oxygen-insensitive NAD(P)H nitroreductase this enzyme reduces a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents, two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide); Uses the FMN as cofactor; Belongs to the nitroreductase family; Localized in the cytoplasm; High confidence in function and specificity; 6,7-dihydropteridine reductase 5340691 nfnB3 10977002 nfnB3 Zobellia galactanivorans 6,7-dihydropteridine reductase YP_004739040.1 5340053 R 63186 CDS YP_004739041.1 340620588 10978247 5340713..5340913 1 NC_015844.1 Hypothetical protein; hypothetical protein 5340913 10978247 zobellia_4627 Zobellia galactanivorans hypothetical protein YP_004739041.1 5340713 D 63186 CDS YP_004739042.1 340620589 10977003 5341040..5342335 1 NC_015844.1 Conserved amino acid transporter. Its exact specificity is unknown. Features twelve transmembrane helices. Localized in the cytoplasmic membrane.; Family membership; amino acid transporter 5342335 10977003 zobellia_4628 Zobellia galactanivorans amino acid transporter YP_004739042.1 5341040 D 63186 CDS YP_004739043.1 340620590 10977004 5342436..5343092 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 5343092 10977004 zobellia_4629 Zobellia galactanivorans hypothetical protein YP_004739043.1 5342436 D 63186 CDS YP_004739044.1 340620591 10977005 5343008..5343391 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 5343391 10977005 zobellia_4630 Zobellia galactanivorans hypothetical protein YP_004739044.1 5343008 D 63186 CDS YP_004739045.1 340620593 10977006 complement(5343381..5343530) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5343530 10977006 zobellia_4632 Zobellia galactanivorans hypothetical protein YP_004739045.1 5343381 R 63186 CDS YP_004739046.1 340620592 10977008 5343496..5343618 1 NC_015844.1 Hypothetical protein; hypothetical protein 5343618 10977008 zobellia_4631 Zobellia galactanivorans hypothetical protein YP_004739046.1 5343496 D 63186 CDS YP_004739047.1 340620594 10977007 complement(5343996..5344637) 1 NC_015844.1 Response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA- binding activity (here, a LuxR-type HTH domain) that acts as transcriptional regulator; Family membership; two-component system-response regulator 5344637 10977007 zobellia_4633 Zobellia galactanivorans two-component system-response regulator YP_004739047.1 5343996 R 63186 CDS YP_004739048.1 340620595 10977009 complement(5345351..5347225) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 28 and 29; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5347225 10977009 zobellia_4634 Zobellia galactanivorans periplasmic protein YP_004739048.1 5345351 R 63186 CDS YP_004739049.1 340620596 10977010 complement(5347404..5348666) 1 NC_015844.1 Protein belonging to the OmpA family. OmpA-like domains are thought to be responsible for non-covalent interactions with peptidoglycan; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Family membership; OmpA-like outer membrane protein 5348666 10977010 zobellia_4635 Zobellia galactanivorans OmpA-like outer membrane protein YP_004739049.1 5347404 R 63186 CDS YP_004739050.1 340620597 10977011 complement(5348739..5348837) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5348837 10977011 zobellia_4636 Zobellia galactanivorans hypothetical protein YP_004739050.1 5348739 R 63186 CDS YP_004739051.1 340620598 10977012 5349266..5350255 1 NC_015844.1 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity; glyceraldehyde 3-phosphate dehydrogenase 5350255 gapB 10977012 gapB Zobellia galactanivorans glyceraldehyde 3-phosphate dehydrogenase YP_004739051.1 5349266 D 63186 CDS YP_004739052.1 340620600 10977878 complement(5350327..5350455) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5350455 10977878 zobellia_4639 Zobellia galactanivorans hypothetical protein YP_004739052.1 5350327 R 63186 CDS YP_004739053.1 340620599 10977013 5350384..5351478 1 NC_015844.1 Aldose 1-epimerase or Mutarotase is responsible for the anomeric interconversion of aldoses between their alpha- and beta-forms; It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; Signal peptide cleaved between the residues 20 and 21; Putatively localized in the outer membrane; High confidence in function and specificity; aldose 1-epimerase 5351478 mroA5 10977013 mroA5 Zobellia galactanivorans aldose 1-epimerase YP_004739053.1 5350384 D 63186 CDS YP_004739054.1 340620601 10978187 complement(5351491..5352339) 1 NC_015844.1 Conserved protein belonging to the NmrA-type oxidoreductase family, but its exact function is unknown. NmrA is a negative transcriptional regulator involved in the control of nitrogen metabolite repression in various fungi. Its crystal structure has revealed an unexpected similarity to the short-chain dehydrogenase/reductase (SDR) family. NAD binds to NmrA in vitro. Localized in the cytoplasm.; Family membership; NmrA family oxidoreductase 5352339 10978187 zobellia_4640 Zobellia galactanivorans NmrA family oxidoreductase YP_004739054.1 5351491 R 63186 CDS YP_004739055.1 340620602 10977014 complement(5352361..5352558) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5352558 10977014 zobellia_4641 Zobellia galactanivorans hypothetical protein YP_004739055.1 5352361 R 63186 CDS YP_004739056.1 340620603 10977015 complement(5352664..5353047) 1 NC_015844.1 Contains an uncleavable signal sequence; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5353047 10977015 zobellia_4642 Zobellia galactanivorans hypothetical protein YP_004739056.1 5352664 R 63186 CDS YP_004739057.1 340620604 10977016 complement(5353145..5354005) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 5354005 10977016 zobellia_4643 Zobellia galactanivorans AraC family transcriptional regulator YP_004739057.1 5353145 R 63186 CDS YP_004739058.1 340620605 10977017 complement(5354203..5355327) 1 NC_015844.1 Conserved protein containing two fascilin domains. These domains, also known as FAS1 or BIgH3 domains, are extracellular modules of about 140 amino acid residues. Each fascilin domain consists of seven-stranded wedge and at least five alpha helices; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 25 and 26, Localized in the outer membrane; Family membership; fasciclin repeat-containing protein 5355327 10977017 zobellia_4644 Zobellia galactanivorans fasciclin repeat-containing protein YP_004739058.1 5354203 R 63186 CDS YP_004739059.1 340620606 10977018 complement(5355437..5357284) 1 NC_015844.1 The Di-heme cytochrome c peroxidase reduces hydrogen peroxide to water using c-type heme as an oxidizable substrate. However, since it possesses two, instead of one, heme prosthetic groups, CcpA reduce hydrogen peroxide without the need to generate semi-stable free radicals; CcpA is structured into two domains, each containing one c-type heme group, with a calcium-binding site at the domain interface; Putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; High confidence in function and specificity; di-heme cytochrome c peroxidase 5357284 ccpA3 10977018 ccpA3 Zobellia galactanivorans di-heme cytochrome c peroxidase YP_004739059.1 5355437 R 63186 CDS YP_004739060.1 340620607 10977637 complement(5357370..5358908) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Lcocalized in the outer membrane; hypothetical protein 5358908 10977637 zobellia_4646 Zobellia galactanivorans hypothetical protein YP_004739060.1 5357370 R 63186 CDS YP_004739061.1 340620608 10977019 complement(5359167..5360306) 1 NC_015844.1 To protect the bacterium against osmotic shock, the periplasmic glucose-fructose oxidoreductase produces the compatible, solute sorbitol by reduction of fructose, coupled with the oxidation of glucose to gluconolactone. GfoA formes a homodimer and each subunit contains tightly associated NADP which is not released during the catalytic cycle. It belongs to the GFO/IDH/MOCA family and adopts a Rossmann fold. Features an uncleaved signal peptide. Localized in the periplasm.; High confidence in function and specificity; glucose-fructose oxidoreductase 5360306 gfoA 10977019 gfoA Zobellia galactanivorans glucose-fructose oxidoreductase YP_004739061.1 5359167 R 63186 CDS YP_004739062.1 340620609 10977892 5360474..5360725 1 NC_015844.1 Contains a C-terminal transmembrane helix; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5360725 10977892 zobellia_4648 Zobellia galactanivorans hypothetical protein YP_004739062.1 5360474 D 63186 CDS YP_004739063.1 340620610 10977020 5360796..5361266 1 NC_015844.1 Contains three transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5361266 10977020 zobellia_4649 Zobellia galactanivorans hypothetical protein YP_004739063.1 5360796 D 63186 CDS YP_004739064.1 340620611 10977021 5361280..5361966 1 NC_015844.1 Acetylesterase that belongs to the lipase-GDSL Pfam family, which includes families 3 and 12 of the carbohydrate esterases (CE3, CE12). The conserved catalytic residues are Ser54, Asp202 and His205. Features an uncleaved signal peptide.; Specificity unclear; lipase-GDSL family acetylesterase 5361966 10977021 zobellia_4650 Zobellia galactanivorans lipase-GDSL family acetylesterase YP_004739064.1 5361280 D 63186 CDS YP_004739065.1 340620612 10977022 5362042..5363802 1 NC_015844.1 Flavin containing amine oxidoreductase which consists of a DAO (D-amino acid oxidase) domain; Use FAD as cofactor; Could be involved in the carotenoid biosynthesis; Belongs to the carotenoid/retinoid oxidoreductase family; Localized in the cytoplasm; Function unclear; flavin containing amine oxidoreductase 5363802 10977022 zobellia_4651 Zobellia galactanivorans flavin containing amine oxidoreductase YP_004739065.1 5362042 D 63186 CDS YP_004739066.1 340620613 10977023 5363903..5364166 1 NC_015844.1 Hypothetical protein; hypothetical protein 5364166 10977023 zobellia_4652 Zobellia galactanivorans hypothetical protein YP_004739066.1 5363903 D 63186 CDS YP_004739067.1 340620614 10977024 complement(5364176..5365336) 1 NC_015844.1 Galactonate dehydratase is involved in the galactose metabolism. It converts the D-galactonate to 2-dehydro-3-deoxy-D-galactonate; Contains a N-terminal Enolase N-terminal domain-like fold and a C-terminal TIM alpha/beta barrel fold; Belongs to the Mandelate racemase/muconate lactonizing enzyme family; Localized in the cytoplasm; High confidence in function and specificity; galactonate dehydratase 5365336 dgoD 10977024 dgoD Zobellia galactanivorans galactonate dehydratase YP_004739067.1 5364176 R 63186 CDS YP_004739068.1 340620615 10977738 complement(5365368..5366669) 1 NC_015844.1 Involved in the intake of galactonate into the cell; The major facilitator superfamily (MFS) transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients; Contains 11 transmembrane segments; Localized in the cytoplasmic membrane; High confidence in function and specificity; D-galactonate transporter 5366669 dgoT 10977738 dgoT Zobellia galactanivorans D-galactonate transporter YP_004739068.1 5365368 R 63186 CDS YP_004739069.1 340620616 10977741 complement(5366976..5369513) 1 NC_015844.1 Enzyme belonging to the family 2 of glycoside hydrolases (GH2) which catalyzes the hydrolysis of the beta-1,4 linkage at the terminal non-reducing of beta-D-galactosides, releasing a beta-D-galactose residue; Signal peptide of lipoprotein cleaved between residues 17 and 18; Possibly localized in the outer membrane; High confidence in function and specificity; beta-galactosidase 5369513 bgaF 10977741 bgaF Zobellia galactanivorans beta-galactosidase YP_004739069.1 5366976 R 63186 CDS YP_004739070.1 340620617 10977598 complement(5369629..5370645) 1 NC_015844.1 L-rhamnose/proton symporter is involved in the uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell. Can also transport L-mannose and L-xylose, but at reduced rates. Contains ten transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; L-rhamnose/proton symporter 5370645 rhaT2 10977598 rhaT2 Zobellia galactanivorans L-rhamnose/proton symporter YP_004739070.1 5369629 R 63186 CDS YP_004739071.1 340620618 10978455 complement(5370706..5371749) 1 NC_015844.1 Aldose 1-epimerase or Mutarotase is responsible for the anomeric interconversion of aldoses between their alpha- and beta-forms; It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; Localized in cytoplasm; High confidence in function and specificity; aldose 1-epimerase 5371749 mroA6 10978455 mroA6 Zobellia galactanivorans aldose 1-epimerase YP_004739071.1 5370706 R 63186 CDS YP_004739072.1 340620619 10978188 complement(5371787..5372881) 1 NC_015844.1 Galactonate dehydratase is involved in the galactose metabolism. It converts the D-galactonate to 2-dehydro-3-deoxy-D-galactonate; Contains a N-terminal domain with a Enolase N-terminal domain-like fold and a C-terminal TIM alpha/beta barrel fold; Belongs to the Mandelate racemase / muconate lactonizing enzyme family; Localized in the cytoplasm; High confidence in function and specificity; galactonate dehydratase 5372881 10978188 zobellia_4658 Zobellia galactanivorans galactonate dehydratase YP_004739072.1 5371787 R 63186 CDS YP_004739073.1 340620620 10977025 complement(5372882..5374336) 1 NC_015844.1 Lactaldehyde dehydrogenase is involved in the catabolism of L-fucose and L-rhamnose and is induced by these sugars. AldA catalyzes the NAD-dependent oxidation of lactaldehyde into lactate; Forms a tetramer; Belongs to the aldehyde dehydrogenase fold family; Localized in the cytoplasm; High confidence in function and specificity; Lactaldehyde dehydrogenase 5374336 aldA 10977025 aldA Zobellia galactanivorans Lactaldehyde dehydrogenase YP_004739073.1 5372882 R 63186 CDS YP_004739074.1 340620621 10977492 complement(5374350..5375738) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 19; Signal peptide cleaved between the residues 22 and 23; Localized in the periplasmic space; Family membership; sulfatase 5375738 10977492 zobellia_4660 Zobellia galactanivorans sulfatase YP_004739074.1 5374350 R 63186 CDS YP_004739075.1 340620622 10977027 complement(5375784..5376554) 1 NC_015844.1 Enzyme that belongs to the Pentose and glucuronate interconversions pathway; Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; High confidence in function and specificity; 2-deoxy-D-gluconate-3-dehydrogenase 5376554 kduD1 10977027 kduD1 Zobellia galactanivorans 2-deoxy-D-gluconate-3-dehydrogenase YP_004739075.1 5375784 R 63186 CDS YP_004739076.1 340620623 10978060 complement(5376579..5377595) 1 NC_015844.1 The long chain dehydrogenases/reductases are zinc-containing enzymes. Zinc-dependant enzymes are dimeric or tetrameric enzymes that bind two atoms of zinc per subunit where one of the zinc atom is essential for catalytic activity while the other is not. The catalytic zinc is coordinated by two cysteines and one histidine; Contains a C-terminal domain having a classical Rossman-fold that reversibly binds NAD(H); The N-terminal domain of alcohol dehydrogenase-like proteins have a GroES-like fold; Localized in the cytoplasm; Family membership; long chain dehydrogenase/reductase 5377595 10978060 zobellia_4662 Zobellia galactanivorans long chain dehydrogenase/reductase YP_004739076.1 5376579 R 63186 CDS YP_004739077.1 340620624 10977028 complement(5377609..5378835) 1 NC_015844.1 Contains a lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; hypothetical protein 5378835 10977028 zobellia_4663 Zobellia galactanivorans hypothetical protein YP_004739077.1 5377609 R 63186 CDS YP_004739078.1 340620625 10977029 complement(5378887..5379618) 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 5379618 10977029 zobellia_4664 Zobellia galactanivorans AraC family transcriptional regulator YP_004739078.1 5378887 R 63186 CDS YP_004739079.1 340620626 10977030 complement(5379863..5380654) 1 NC_015844.1 IclR-type transcriptional regulators display a Helix-Turn-Helix motif at the N-terminus. Localized in the cytoplasm.; Specificity unclear; IclR-type transcriptional regulator 5380654 10977030 zobellia_4665 Zobellia galactanivorans IclR-type transcriptional regulator YP_004739079.1 5379863 R 63186 CDS YP_004739080.1 340620627 10977031 complement(5380750..5382393) 1 NC_015844.1 Contains a N-terminal transmembrane segement followed by three tetratricopeptide repeats (TPR) and a C-terminal LuxR-type HTH domain. Between the TPR and HTH domains a second transmembrane segement is present; This Protein could interact with the DNA (transcriptional control or transcription factor); Probably localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5382393 10977031 zobellia_4666 Zobellia galactanivorans membrane protein YP_004739080.1 5380750 R 63186 CDS YP_004739081.1 340620628 10977032 complement(5382397..5382642) 1 NC_015844.1 Sequence that displays some similarities with the C-terminal end of several paralogous proteins; Putatively localized in the cytoplasm; hypothetical protein 5382642 10977032 zobellia_4667 Zobellia galactanivorans hypothetical protein YP_004739081.1 5382397 R 63186 CDS YP_004739082.1 340620629 10977033 complement(5383625..5385373) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 5385373 10977033 zobellia_4668 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004739082.1 5383625 R 63186 CDS YP_004739083.1 340620630 10977034 complement(5385394..5388576) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (27-99) and the Plug module (115-218) acting as a channel gate; The signal peptide is cleaved between the residues 25 and 26; Family membership; TonB-dependent Receptor 5388576 10977034 zobellia_4669 Zobellia galactanivorans TonB-dependent Receptor YP_004739083.1 5385394 R 63186 CDS YP_004739084.1 340620631 10977035 complement(5388816..5389040) 1 NC_015844.1 Hypothetical protein; hypothetical protein 5389040 10977035 zobellia_4670 Zobellia galactanivorans hypothetical protein YP_004739084.1 5388816 R 63186 CDS YP_004739085.1 340620632 10977037 complement(5389062..5389859) 1 NC_015844.1 IclR-type transcriptional regulators display a Helix-Turn-Helix motif at the N-terminus. Localized in the cytoplasm.; Specificity unclear; IclR-type transcriptional regulator 5389859 10977037 zobellia_4671 Zobellia galactanivorans IclR-type transcriptional regulator YP_004739085.1 5389062 R 63186 CDS YP_004739086.1 340620633 10977038 complement(5390232..5391848) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Putative lipoprotein signal peptide cleaved between the residue 18 and 19; Possibly localized in the outer membrane; Family membership; sulfatase 5391848 10977038 zobellia_4672 Zobellia galactanivorans sulfatase YP_004739086.1 5390232 R 63186 CDS YP_004739087.1 340620634 10977039 complement(5391955..5392746) 1 NC_015844.1 Carbohydrate esterases catalyze the de-O or de-N-acetylation of substituted saccharides; Belongs to the family 1 of the carbohydrate esterases (CE1); Localized in the cytoplasm; Specificity unclear; carbohydrate esterase 5392746 10977039 zobellia_4673 Zobellia galactanivorans carbohydrate esterase YP_004739087.1 5391955 R 63186 CDS YP_004739088.1 340620635 10977040 complement(5392755..5393873) 1 NC_015844.1 Oxidizes long-chain aliphatic alcohols, long-chain hydroxylated fatty acids and S-hydroxymethylglutathione (hmGSH) in increasing order of preference. Shows little or no activity with short-chain aliphatic alcohols; Contains two zinc atoms. One is essential for catalytic activity while the other is not; Possibly involved in the metabolism of xenobiotics by cytochrome P450; Belongs to the zinc-containing alcohol dehydrogenase family, class- III subfamily; Localized in the cytoplasm; High confidence in function and specificity; alcohol dehydrogenase class 3 / S-(hydroxymethyl)glutathione dehydrogenase 5393873 adhI 10977040 adhI Zobellia galactanivorans alcohol dehydrogenase class 3 / S-(hydroxymethyl)glutathione dehydrogenase YP_004739088.1 5392755 R 63186 CDS YP_004739089.1 340620636 10977474 complement(5393917..5395173) 1 NC_015844.1 The oxidation of substrat by a cytochrome P450 requires the participation of a flavoprotein such as ferredoxin reductase, and an iron-sulfur protein such as ferredoxin, to mediate the transfer of electrons from NADH to P450 for oxygen activation; Uses the FAD as cofactor; Belongs to the FAD-dependent oxidoreductase family, ferredoxin-NADP reductase sub-family; Localized in the cytoplasm; Specificity unclear; ferredoxin reductase 5395173 10977474 zobellia_4675 Zobellia galactanivorans ferredoxin reductase YP_004739089.1 5393917 R 63186 CDS YP_004739090.1 340620637 10977041 complement(5395181..5395489) 1 NC_015844.1 Ferredoxins are electron carrier proteins with an iron-sulfur as cofactor and that transfer electrons in a wide variety of metabolic reactions. Belongs to the putidaredoxin, terpredoxin and adrenodoxin sub-family and uses 2Fe-2S cluster as cofactor ligated at four conserved cysteine residues. The general core structure consists of beta(2)-alpha-beta(2). Localized in the cytoplasm.; High confidence in function and specificity; 2Fe-2S ferredoxin 5395489 fdxA3 10977041 fdxA3 Zobellia galactanivorans 2Fe-2S ferredoxin YP_004739090.1 5395181 R 63186 CDS YP_004739091.1 340620638 10977826 complement(5395494..5396657) 1 NC_015844.1 Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics; P450 enzymes usually act as terminal oxidases in multicomponent electron transfer chains, called P450-containing monooxygenase systems; Acts with the ferredoxin and the ferredoxin reductase; Localized in the cytoplasm; Specificity unclear; cytochrome P450 5396657 cypA 10977826 cypA Zobellia galactanivorans cytochrome P450 YP_004739091.1 5395494 R 63186 CDS YP_004739092.1 340620639 10977699 5396843..5397682 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 5397682 10977699 zobellia_4678 Zobellia galactanivorans AraC family transcriptional regulator YP_004739092.1 5396843 D 63186 CDS YP_004739093.1 340620640 10977042 5397855..5399396 1 NC_015844.1 The alpha-L-fucosidase is responsible for hydrolyzing of alpha-1,6-linked fucose joined to an alpha-L-fucoside; Belongs to the family 29 of glycoside hydrolases (GH29); Signal peptide of lipoprotein cleaved between the residue 16 and 17; Probably localized in the outer membrane; High confidence in function and specificity; alpha-L-fucosidase 5399396 fucA9 10977042 fucA9 Zobellia galactanivorans alpha-L-fucosidase YP_004739093.1 5397855 D 63186 CDS YP_004739094.1 340620641 10977866 5399573..5400589 1 NC_015844.1 The long chain dehydrogenases/reductases are zinc-containing enzymes. Zinc-dependant enzymes are dimeric or tetrameric enzymes that bind two atoms of zinc per subunit where one of the zinc atom is essential for catalytic activity while the other is not. The catalytic zinc is coordinated by two cysteines and one histidine; Contains a C-terminal domain having a classical Rossman-fold that reversibly binds NAD(H); The N-terminal domain of alcohol dehydrogenase-like proteins have a GroES-like fold; Localized in the cytoplasm; Family membership; long chain dehydrogenase/reductase 5400589 10977866 zobellia_4680 Zobellia galactanivorans long chain dehydrogenase/reductase YP_004739094.1 5399573 D 63186 CDS YP_004739095.1 340620642 10977043 5400627..5402279 1 NC_015844.1 Altronate hydrolase or Altronic acid hydratase converts the altronic acid to 2-keto-2-deoxygluconate; it is catalytically inactive in the absence of Fe2+, Mn2+, and beta-mercaptoethanol. Synergistic activation of enzyme is seen in the presence of both iron and manganese ions, suggesting that the enzyme may have two ion binding sites. Mn2+ appears to be part of the enzyme active centre; Contains an N-terminal SAF domain; Localized in the cytoplasm; High confidence in function and specificity; altronate hydrolase 5402279 uxaA 10977043 uxaA Zobellia galactanivorans altronate hydrolase YP_004739095.1 5400627 D 63186 CDS YP_004739096.1 340620643 10978736 5402318..5403766 1 NC_015844.1 Altronate oxidoreductase or Tagaturonate reductase catalyzes the NAD-dependent reduction of altronate into tagaturonate; Belongs to the Long-chain mannitol dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity; altronate oxidoreductase 5403766 uxaB 10978736 uxaB Zobellia galactanivorans altronate oxidoreductase YP_004739096.1 5402318 D 63186 CDS YP_004739097.1 340620644 10978737 5403794..5404621 1 NC_015844.1 Belongs to the metal-dependent hydrolase superfamily, Amidohydrolase 2 family; Localized in the cytoplasm; Family membership; amidohydrolase 2 family protein 5404621 10978737 zobellia_4683 Zobellia galactanivorans amidohydrolase 2 family protein YP_004739097.1 5403794 D 63186 CDS YP_004739098.1 340620645 10977044 5404710..5405504 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 5405504 10977044 zobellia_4684 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004739098.1 5404710 D 63186 CDS YP_004739099.1 340620646 10977045 5405529..5406872 1 NC_015844.1 FucP mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose. Features twelve transmembrane helices. Localized in the cytoplasmic membrane.; High confidence in function and specificity; L-fucose-proton symporter 5406872 fucP2 10977045 fucP2 Zobellia galactanivorans L-fucose-proton symporter YP_004739099.1 5405529 D 63186 CDS YP_004739100.1 340620647 10977868 5406874..5407215 1 NC_015844.1 Protein belonging to the DUF718 family, which includes the rhamnose mutarotase YiiL from Escherichia coli; Localized in the cytoplasm; hypothetical protein 5407215 10977868 zobellia_4686 Zobellia galactanivorans hypothetical protein YP_004739100.1 5406874 D 63186 CDS YP_004739101.1 340620648 10977046 complement(5407314..5408993) 1 NC_015844.1 Mucin-desulfating sulfatases hydrolyse the sulfate groups from oligosaccharides present in mucins (heavily glycosylated proteins). In the mucins, the main sulfated sugars are N-acetyl-D-glucosamine-6-sulfate, galactose-6-sulfate and galactose-3-sulfate; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 11; Putative lipoprotein with a signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; Specificity unclear; mucin-desulfating sulfatase 5408993 mdsA7 10977046 mdsA7 Zobellia galactanivorans mucin-desulfating sulfatase YP_004739101.1 5407314 R 63186 CDS YP_004739102.1 340620649 10978138 complement(5409148..5410251) 1 NC_015844.1 This protein likely adopts a beta-propeller fold. Features a twin-arginine signal peptide. Localized in the periplasm.; Family membership; beta-propeller fold protein 5410251 10978138 zobellia_4688 Zobellia galactanivorans beta-propeller fold protein YP_004739102.1 5409148 R 63186 CDS YP_004739103.1 340620650 10977047 complement(5410313..5411830) 1 NC_015844.1 Conserved hypothetical protein (family DUF1501). Belongs to the alkaline-phosphatase clan. Features a twin-arginine signal peptide. Localized in the periplasm.; hypothetical protein 5411830 10977047 zobellia_4689 Zobellia galactanivorans hypothetical protein YP_004739103.1 5410313 R 63186 CDS YP_004739104.1 340620651 10977048 complement(5411857..5415105) 1 NC_015844.1 This protein has a modular architecture composed of a N-terminal cytochrome C, a domain of unknown function (DUF1549) which includes a second cytochrome C, a central domain adopting a jelly roll fold (concavalin A-like) and a C-terminal DUF1553 domain. Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes. The two domains DUF1549 and DUF1553 are usually found in Planctomycetes; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the cytoplasmic and/or outer membrane; Function unclear; cytochrome c-containing protein 5415105 10977048 zobellia_4690 Zobellia galactanivorans cytochrome c-containing protein YP_004739104.1 5411857 R 63186 CDS YP_004739105.1 340620652 10977049 5415163..5415270 1 NC_015844.1 Hypothetical protein; hypothetical protein 5415270 10977049 zobellia_4691 Zobellia galactanivorans hypothetical protein YP_004739105.1 5415163 D 63186 CDS YP_004739106.1 340620653 10977050 5415337..5416200 1 NC_015844.1 The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA and a N-terminal domain presumed to interact with effector molecules and may be involved in dimerization; Localized in the cytoplasm; Family membership; AraC family transcriptional regulator 5416200 10977050 zobellia_4692 Zobellia galactanivorans AraC family transcriptional regulator YP_004739106.1 5415337 D 63186 CDS YP_004739107.1 340620654 10977051 complement(5416204..5417526) 1 NC_015844.1 NAD(P)-dependent dehydrogenase. Belongs to the Rossmann fold family. Contains a twin-arginine translocation signal peptide; Localized in the periplasmic space; Specificity unclear; NAD(P)-dependent dehydrogenase 5417526 10977051 zobellia_4693 Zobellia galactanivorans NAD(P)-dependent dehydrogenase YP_004739107.1 5416204 R 63186 CDS YP_004739108.1 340620655 10977052 complement(5417523..5419352) 1 NC_015844.1 The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the cytoplasmic membrane or/and outer membrane; Family membership; sulfatase 5419352 10977052 zobellia_4694 Zobellia galactanivorans sulfatase YP_004739108.1 5417523 R 63186 CDS YP_004739109.1 340620656 10977053 complement(5419363..5423583) 1 NC_015844.1 The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; one-component system sensor protein 5423583 10977053 zobellia_4695 Zobellia galactanivorans one-component system sensor protein YP_004739109.1 5419363 R 63186 CDS YP_004739110.1 340620657 10977054 complement(5423767..5427111) 1 NC_015844.1 ASPIC and UnbV sequences are found associated with tetratrico peptide repeat in several paralogous proteins in Rhodopirellula baltica and with FG-GAP repeats in several eukaryotic integrin-like proteins and in several other bacterial proteins. The FG-GAP repeat has been predicted to fold into a beta propeller structure. The FG- GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding; Contains a signal peptide uncleavable (residues 5 to 23) that would localize the protein in the cytoplsmic membrane (PSORT result); Function unclear; ASPIC/UnbV-like protein 5427111 10977054 zobellia_4696 Zobellia galactanivorans ASPIC/UnbV-like protein YP_004739110.1 5423767 R 63186 CDS YP_004739111.1 340620658 10977055 complement(5427131..5430481) 1 NC_015844.1 ASPIC and UnbV sequences are found associated with tetratrico peptide repeat in several paralogous proteins in Rhodopirellula baltica and with FG-GAP repeats in several eukaryotic integrin-like proteins and in several other bacterial proteins. The FG-GAP repeat has been predicted to fold into a beta propeller structure. The FG- GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding; Contains a signal peptide of lipoprotein cleaved between the residues 23 and 24; Protein putatively localized in the outer membrane; Function unclear; ASPIC/UnbV-like protein 5430481 10977055 zobellia_4697 Zobellia galactanivorans ASPIC/UnbV-like protein YP_004739111.1 5427131 R 63186 CDS YP_004739112.1 340620659 10977056 complement(5430623..5432101) 1 NC_015844.1 Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Contains a lipoprotein signal peptide cleaved between the residues 25 and 26; Localized in the outer membrane; Family membership; SusD/RagB family lipoprotein 5432101 10977056 zobellia_4698 Zobellia galactanivorans SusD/RagB family lipoprotein YP_004739112.1 5430623 R 63186 CDS YP_004739113.1 340620660 10977057 complement(5432106..5435219) 1 NC_015844.1 Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (34-107) and the Plug module (123-228) acting as a channel gate; The signal peptide is cleaved between the residues 27 and 28; Family membership; TonB-dependent Receptor 5435219 10977057 zobellia_4699 Zobellia galactanivorans TonB-dependent Receptor YP_004739113.1 5432106 R 63186 CDS YP_004739114.1 340620661 10977058 5435583..5436398 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Possible signal peptide cleaved between the residues 30 and 31; Putatively localized in the periplasmic space; Family membership; short-chain dehydrogenase/reductase 5436398 10977058 zobellia_4700 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004739114.1 5435583 D 63186 CDS YP_004739115.1 340620662 10977061 5436466..5437668 1 NC_015844.1 Mannonate dehydratase, induced By fructuronate, is a Fe2+-requiring enzyme that plays a role in D-glucuronate catabolism; Mannonate dehydratase converts D-mannonate to 2-dehydro-3-deoxy-D-gluconate; Localized in the cytoplasm; High confidence in function and specificity; mannonate dehydratase 5437668 uxuA2 10977061 uxuA2 Zobellia galactanivorans mannonate dehydratase YP_004739115.1 5436466 D 63186 CDS YP_004739116.1 340620663 10978740 complement(5437672..5438340) 1 NC_015844.1 KHG/KDPG aldolase is a bifunctional enzyme catalyzing the interconversion of 4-hydroxy-2-oxoglutarate into pyruvate and glyoxylate (4-Hydroxy-2-oxoglutarate aldolase activity) and the interconversion of 6-phospho-2-dehydro-3-deoxy-D-gluconate into pyruvate and glyceraldehyde 3-phosphate (Phospho-2-dehydro-3-deoxygluconate aldolase activity). This enzyme is involved in the Entner-Doudoroff pathway and in the glyoxylate and dicarboxylate metabolism; Belongs to the class I aldolase whose catalytic mechanism involves the formation of a Schiff-base intermediate between the substrate and the epsilon-amino group of a lysine residue; Localized in the cytoplasm; High confidence in function and specificity; KHG/KDPG aldolase 5438340 eda 10978740 eda Zobellia galactanivorans KHG/KDPG aldolase YP_004739116.1 5437672 R 63186 CDS YP_004739117.1 340620664 10977775 complement(5438365..5439405) 1 NC_015844.1 The 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP)in the Entner-Doudoroff Pathway. KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources; Belongs to the Carbohydrate kinase, PfkB family, 2-dehydro-3-deoxygluconokinase (KdgK) subfamily; Localized in the cytoplasm; High confidence in function and specificity; 2-dehydro-3-deoxygluconokinase 5439405 kdgK2 10977775 kdgK2 Zobellia galactanivorans 2-dehydro-3-deoxygluconokinase YP_004739117.1 5438365 R 63186 CDS YP_004739118.1 340620665 10978054 5439555..5439650 1 NC_015844.1 Hypothetical protein; hypothetical protein 5439650 10978054 zobellia_4704 Zobellia galactanivorans hypothetical protein YP_004739118.1 5439555 D 63186 CDS YP_004739119.1 340620666 10977062 5439695..5440402 1 NC_015844.1 Contains seven transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5440402 10977062 zobellia_4705 Zobellia galactanivorans membrane protein YP_004739119.1 5439695 D 63186 CDS YP_004739120.1 340620667 10977063 5440409..5440930 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5440930 10977063 zobellia_4706 Zobellia galactanivorans hypothetical protein YP_004739120.1 5440409 D 63186 CDS YP_004739121.1 340620668 10977064 complement(5440968..5441894) 1 NC_015844.1 Signal peptide cleaved between the residues 20 and 21; Putatively localized in the outer membrane; Conserved hypothetical protein; membrane protein 5441894 10977064 zobellia_4707 Zobellia galactanivorans membrane protein YP_004739121.1 5440968 R 63186 CDS YP_004739122.1 340620669 10977065 complement(5442109..5444016) 1 NC_015844.1 DnaK is an molecular chaperones that couples cycles of ATP binding, hydrolysis, and ADP release by an N-terminal ATP-hydrolysing domain to cycles of sequestration and release of unfolded proteins by a C-terminal substrate binding domain. Acts in association with the co-chaperones GrpE (stimulates the rate of ADP release) and DnaJ (stimulates the ATPase activity; Protein induced By stress conditions e.g. heat shock; Belongs to the heat shock protein 70 (hsp70) family; Localized in the cytoplasm; High confidence in function and specificity; molecular chaperone DnaK 5444016 dnaK 10977065 dnaK Zobellia galactanivorans molecular chaperone DnaK YP_004739122.1 5442109 R 63186 CDS YP_004739123.1 340620670 10977754 5444336..5445763 1 NC_015844.1 L-serine dehydratase is involved in the gluconeogenesis pathway. It catalyzes the deamination of serine to form pyruvate. It is activated by a post-translational modification via a system involving at least three gene products. There is considerable evidence for a free-radical activation mechanism; Binds a 4Fe-4S cluster as a cofactor; Localized in the cytoplasm; High confidence in function and specificity; L-serine dehydratase 5445763 sdaA2 10977754 sdaA2 Zobellia galactanivorans L-serine dehydratase YP_004739123.1 5444336 D 63186 CDS YP_004739124.1 340620671 10978570 5445832..5446395 1 NC_015844.1 The Crp/Fnr-type transcriptional regulators complexe with cyclic AMP and bind to operator sites near the promoter with a C-terminal HTH domain to regulate the transcription of several catabolite-sensitive operons; They predominantly act as transcription activators, but can also be important repressors, and respond to diverse intracellular and exogenous signals; Localized in the cytoplasm; Family membership; Crp/Fnr-type transcriptional regulator 5446395 10978570 zobellia_4710 Zobellia galactanivorans Crp/Fnr-type transcriptional regulator YP_004739124.1 5445832 D 63186 CDS YP_004739125.1 340620672 10977067 5446468..5446794 1 NC_015844.1 SugE is a quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations. Unlike the other members of the small multidrug resistance (SMR) protein family, sugE exhibits a narrow specificity for a very specific class of compounds; Contains four transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity; Quaternary ammonium compound-resistance protein sugE 5446794 sugE 10977067 sugE Zobellia galactanivorans Quaternary ammonium compound-resistance protein sugE YP_004739125.1 5446468 D 63186 CDS YP_004739126.1 340620673 10978624 5446952..5447737 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5447737 10978624 zobellia_4712 Zobellia galactanivorans hypothetical protein YP_004739126.1 5446952 D 63186 CDS YP_004739127.1 340620674 10977068 5447829..5448626 1 NC_015844.1 Endonuclease acting on both DNA and RNA. Cleaves double-stranded and single-stranded nucleic acids and requires. A catalytic histidine is located in a conserved region which also contains an aspartate that could be implicated in the binding of the divalent ion; Uses a divalent ion such as magnesium as cofactor; Localized in the cytoplasm; Specificity unclear; DNA/RNA non-specific endonuclease 5448626 10977068 zobellia_4713 Zobellia galactanivorans DNA/RNA non-specific endonuclease YP_004739127.1 5447829 D 63186 CDS YP_004739128.1 340620675 10977069 complement(5448688..5449629) 1 NC_015844.1 Protein belonging to the DUF1080 family; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasmic space; Hypothetical protein; periplasmic protein 5449629 10977069 zobellia_4714 Zobellia galactanivorans periplasmic protein YP_004739128.1 5448688 R 63186 CDS YP_004739129.1 340620676 10977070 5449794..5451260 1 NC_015844.1 NAD(P)-dependent dehydrogenase; Belongs to the Rossmann fold family; Contains a twin-arginine translocation signal peptide; Localized in the periplasmic space; Specificity unclear; NAD(P)-dependent dehydrogenase 5451260 10977070 zobellia_4715 Zobellia galactanivorans NAD(P)-dependent dehydrogenase YP_004739129.1 5449794 D 63186 CDS YP_004739130.1 340620677 10977071 complement(5451323..5451781) 1 NC_015844.1 Signal peptide cleaved between the residues 18 and 19; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5451781 10977071 zobellia_4716 Zobellia galactanivorans periplasmic protein YP_004739130.1 5451323 R 63186 CDS YP_004739131.1 340620678 10977072 5451932..5452750 1 NC_015844.1 3-Methyl-2-oxobutanoate hydroxymethyltransferase catalyzes the first step in the biosynthesis of pantothenate (vitamin B5), the precursor of coenzyme A and of the acyl carrier protein cofactor. The hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate; Forms a Homodecamer (pentamer of dimers); Binds 1 magnesium ion per subunit; Localized in the cytoplasm; High confidence in function and specificity; 3-methyl-2-oxobutanoate hydroxymethyltransferase 5452750 panB 10977072 panB Zobellia galactanivorans 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_004739131.1 5451932 D 63186 CDS YP_004739132.1 340620679 10978297 5452807..5453505 1 NC_015844.1 Enzyme responsible for synthesis of pseudouridine from uracil at position 65 in transfert RNA by rotation of the C1'-N-1 glycosidic bond of uridine to a C1'-C5; Belongs to the pseudouridine synthase RluA family; localized in the cytoplasm; High confidence in function and specificity; tRNA pseudouridine synthase C 5453505 truC 10978297 truC Zobellia galactanivorans tRNA pseudouridine synthase C YP_004739132.1 5452807 D 63186 CDS YP_004739133.1 340620680 10978704 5453539..5454084 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 16 and 17; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 5454084 10978704 zobellia_4719 Zobellia galactanivorans lipoprotein YP_004739133.1 5453539 D 63186 CDS YP_004739134.1 340620681 10977073 complement(5454204..5455691) 1 NC_015844.1 Cytochrome c Snr1 is required for Nitrate Reduction. In the C-type cytochromes, the heme group is covalently attached by thioether bonds to two conserved cysteine residues (Cys-x-x-Cys-His). The conserved histidine residue is one of the two axial ligands of the heme iron. Cytochromes c typically function in electron transfer, but c-type cytochrome centers are also found in the active sites of many enzymes; contains a N-terminal domain of unknown function and a C-terminal cytochrome C domain; Signal peptide cleaved between the residues 24 and 25; Localized in the periplasm.; High confidence in function and specificity; cytochrome c Snr1 5455691 snr1 10977073 snr1 Zobellia galactanivorans cytochrome c Snr1 YP_004739134.1 5454204 R 63186 CDS YP_004739135.1 340620682 10978600 complement(5455990..5456799) 1 NC_015844.1 Integral membrane protein belonging to the DUF6 family; Contains nine transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5456799 10978600 zobellia_4721 Zobellia galactanivorans membrane protein YP_004739135.1 5455990 R 63186 CDS YP_004739136.1 340620683 10977074 complement(5456857..5458401) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5458401 10977074 zobellia_4722 Zobellia galactanivorans hypothetical protein YP_004739136.1 5456857 R 63186 CDS YP_004739137.1 340620684 10977075 5458674..5459846 1 NC_015844.1 2-Isopropylmalate synthase catalyzes the first step in the L-leucine biosynthesis pathway. LeuA condensates the acetyl group of acetyl-CoA with 3-methyl-2- oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). LeuA2 is a paralogue of leuA1 which misses the C-terminal LeuA-dimerization domain. Localized in the cytoplasm.; Specificity unclear; 2-Isopropylmalate synthase 5459846 leuA2 10977075 leuA2 Zobellia galactanivorans 2-Isopropylmalate synthase YP_004739137.1 5458674 D 63186 CDS YP_004739138.1 340620685 10978081 5459983..5461101 1 NC_015844.1 3-Isopropylmalate dehydrogenase catalyzes the third step in the L-leucine biosynthesis pathway. LeuB catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. LeuB forms a homodimer and binds one NAD+ and one Mg2+ or Mn2+ ion by subunit. Localized in the cytoplasm.; High confidence in function and specificity; 3-Isopropylmalate dehydrogenase 5461101 LeuB2 10978081 LeuB2 Zobellia galactanivorans 3-Isopropylmalate dehydrogenase YP_004739138.1 5459983 D 63186 CDS YP_004739139.1 340620686 10978083 complement(5461108..5462328) 1 NC_015844.1 Protein containing a N-terminal domain of unknown function and a C-terminal thiol-disulfide oxidoreductase domain belonging to the thioredoxin family. Thiol-disulfide oxidoreductase catalyzes the formation of disulfide bond in various substrates. Its exact specificity is not known; Putative lipoprotein signal peptide cleaved between the residues 16 and 17; Possibly localized in the outer membrane; Specificity unclear; thiol-disulfide oxidoreductase 5462328 10978083 zobellia_4725 Zobellia galactanivorans thiol-disulfide oxidoreductase YP_004739139.1 5461108 R 63186 CDS YP_004739140.1 340620687 10977076 5462459..5464888 1 NC_015844.1 Phenylalanyl-tRNA synthetase catalyzes the attachment of phenylalanyl to its cognate transfer RNA molecule in a highly specific two-step reaction. It is an alpha2/beta2 tetramer composed of 2 subunits that belongs to class II aminoacyl-tRNA synthetases. PheT codes the beta subunit and folds as an anti-parallel beta-sheet flanked by alpha-helices. Phenylalanyl-tRNA synthetase binds 2 magnesium ions per tetramer. Localized in the cytoplasm.; High confidence in function and specificity; phenylalanyl-tRNA synthetase subunit beta 5464888 pheT 10977076 pheT Zobellia galactanivorans phenylalanyl-tRNA synthetase subunit beta YP_004739140.1 5462459 D 63186 CDS YP_004739141.1 340620688 10978342 complement(5464944..5465498) 1 NC_015844.1 In Eukaryotes, fascilin module containing proteins mediate cell adhesion throught an interaction with alpha3/beta1 integrin; This module, also known as FAS1 or BIgH3 domain, is an extracellular module of about 140 amino acid residues; Contains one only copy of fascilin module; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasm.; Family membership; fasciclin family protein 5465498 10978342 zobellia_4727 Zobellia galactanivorans fasciclin family protein YP_004739141.1 5464944 R 63186 CDS YP_004739142.1 340620689 10977077 5465694..5466413 1 NC_015844.1 Contains two C-terminal transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5466413 10977077 zobellia_4728 Zobellia galactanivorans membrane protein YP_004739142.1 5465694 D 63186 CDS YP_004739143.1 340620690 10977078 complement(5466494..5467642) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 18 and 19; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 5467642 10977078 zobellia_4729 Zobellia galactanivorans lipoprotein YP_004739143.1 5466494 R 63186 CDS YP_004739144.1 340620691 10977079 complement(5467786..5469414) 1 NC_015844.1 This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Contains a duplicated ATPase domain; Belongs to the ABC transporter family, EF3 subfamily; Localized in the cytoplasm near of the cytoplasmic membrane by association with a membrane permease component; Family membership; ABC transporter ATPase 5469414 10977079 zobellia_4730 Zobellia galactanivorans ABC transporter ATPase YP_004739144.1 5467786 R 63186 CDS YP_004739145.1 340620692 10977080 5469595..5470977 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 15 and 16; Localized in the cytoplasmic and/or outer membrane; Conserved hypothetical protein; lipoprotein 5470977 10977080 zobellia_4731 Zobellia galactanivorans lipoprotein YP_004739145.1 5469595 D 63186 CDS YP_004739146.1 340620693 10977081 complement(5471061..5471714) 1 NC_015844.1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. It catalyzes the reversible transfer of a three-carbon ketol unit from sedoheptulose 7-phosphate to glyceraldehyde 3-phosphate to form erythrose 4-phosphate and fructose 6-phosphate. This enzyme, together with transketolase, provides a link between the Embden-Meyerhof pathway and the non-oxidative phase of pentose-phosphate pathway; Localized in the cytoplasm; High confidence in function and specificity; transaldolase 5471714 talA2 10977081 talA2 Zobellia galactanivorans transaldolase YP_004739146.1 5471061 R 63186 CDS YP_004739147.1 340620694 10978637 complement(5471790..5472599) 1 NC_015844.1 Belongs to the short-chain dehydrogenases/reductases (SDR) family; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership; short-chain dehydrogenase/reductase 5472599 10978637 zobellia_4733 Zobellia galactanivorans short-chain dehydrogenase/reductase YP_004739147.1 5471790 R 63186 CDS YP_004739148.1 340620695 10977082 5472950..5474002 1 NC_015844.1 Glutamine cyclotransferase catalyzes the cyclization of free L-glutamine and N-terminal glutaminyl residues in proteins to pyroglutamate (5-oxoproline) and pyroglutamyl residues respectively. It belongs to a family conserved in plants and bacteria, but unrelated to the mammalian enzymes. Localized in the cytoplasm.; High confidence in function and specificity; glutamine cyclotransferase 5474002 10977082 zobellia_4734 Zobellia galactanivorans glutamine cyclotransferase YP_004739148.1 5472950 D 63186 CDS YP_004739149.1 340620696 10977083 5474003..5474404 1 NC_015844.1 Conserved protein belonging to the acyl-CoA thioester hydrolase family. Its exact function is unknown. Localized in the cytoplasm.; Family membership; thioesterase family protein 5474404 10977083 zobellia_4735 Zobellia galactanivorans thioesterase family protein YP_004739149.1 5474003 D 63186 CDS YP_004739150.1 340620697 10977084 5474451..5476013 1 NC_015844.1 Possible lipoprotein that consists of a pectin lyase like domain suggesting a beta helix fold for this protein; Signal peptide cleaved between the residues 25 and 26; probably localized in the outer membrane; Conserved hypothetical protein; beta helix fold protein 5476013 10977084 zobellia_4736 Zobellia galactanivorans beta helix fold protein YP_004739150.1 5474451 D 63186 CDS YP_004739151.1 340620698 10977085 complement(5476133..5476282) 1 NC_015844.1 Contains two transmembrane segments; Possibly localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5476282 10977085 zobellia_4737 Zobellia galactanivorans hypothetical protein YP_004739151.1 5476133 R 63186 CDS YP_004739152.1 340620699 10977086 5476310..5477041 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LytTR-type HTH domain, which acts as transcriptional regulator; Family membership; two-component system-response regulator 5477041 10977086 zobellia_4738 Zobellia galactanivorans two-component system-response regulator YP_004739152.1 5476310 D 63186 CDS YP_004739153.1 340620700 10977087 5477423..5479522 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Lipoprotein signal peptide cleaved between the residues 26 and 27; Contains four N-terminal tetratrico peptide repeats (TPR) and one transmembrane segment; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 5479522 10977087 zobellia_4739 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004739153.1 5477423 D 63186 CDS YP_004739154.1 340620701 10977088 5479547..5480218 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. The protein consists of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity, a LuxR-type HTH domain, which acts as transcriptional regulator; Family membership; two-component system-response regulator 5480218 10977088 zobellia_4740 Zobellia galactanivorans two-component system-response regulator YP_004739154.1 5479547 D 63186 CDS YP_004739155.1 340620702 10977089 5480384..5481040 1 NC_015844.1 Probably a cytoplasmic protein; hypothetical protein 5481040 10977089 zobellia_4741 Zobellia galactanivorans hypothetical protein YP_004739155.1 5480384 D 63186 CDS YP_004739156.1 340620703 10977090 complement(5481171..5482445) 1 NC_015844.1 Serine hydroxymethyltransferase is involved in glycine and serine metabolism. It carries out interconversion of L-serine and glycine using pyridoxal phosphate (PLP) as cofactor. It catalyses the transfer of a hydroxymethyl group from N5, N10- methylene tetrahydrofolate to glycine, resulting in the formation of serine and tetrahydrofolate. It forms a homotetramer. Localized in the cytoplasm.; High confidence in function and specificity; serine hydroxymethyltransferase 5482445 glyA 10977090 glyA Zobellia galactanivorans serine hydroxymethyltransferase YP_004739156.1 5481171 R 63186 CDS YP_004739157.1 340620704 10977935 5482557..5483849 1 NC_015844.1 Fumarylacetoacetase catalyses the hydrolytic cleavage of a carbon-carbon bond in fumarylacetoacetate to yield fumarate and acetoacetate as the final step in phenylalanine and tyrosine degradation. The products then join the citric acid cycle. It forms homodimer and binds one calcium ion and one magnesium ion as cofactors per subunit; Localized in the cytoplasm; Hypothetical protein; fumarylacetoacetase 5483849 fahA 10977935 fahA Zobellia galactanivorans fumarylacetoacetase YP_004739157.1 5482557 D 63186 CDS YP_004739158.1 340620705 10977816 complement(5483907..5484116) 1 NC_015844.1 Localized in the cytoplasm.; hypothetical protein 5484116 10977816 zobellia_4744 Zobellia galactanivorans hypothetical protein YP_004739158.1 5483907 R 63186 CDS YP_004739159.1 340620706 10977091 5484469..5487069 1 NC_015844.1 ClpB is a homohexamer that is a part of a stress-induced multi-chaperone system involved in the recovery of the cell from heat-induced damage, in cooperation with dnaK, dnaJ and grpE. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates contributing to the solubilization and refolding of denatured protein aggregates by dnaK; Contains 2 Clp amino terminal domains that function as a substrate-discriminating domain and 2 AAA ATPase domains; Localized in the cytoplasm; High confidence in function and specificity; chaperone ClpB 5487069 clpB1 10977091 clpB1 Zobellia galactanivorans chaperone ClpB YP_004739159.1 5484469 D 63186 CDS YP_004739160.1 340620707 10977650 5487192..5487788 1 NC_015844.1 Several of these transcriptional regulators are repressors of genes and operons for membrane transport and cell envelope permeability; The helix-turn-helix motif is located in the initial third of the protein. The C-terminal part contains regions that can be involved in binding of inducers, which can be drugs, and oligomerization; Localized in the cytoplasm; Family membership; TetR family transcriptional regulator 5487788 10977650 zobellia_4746 Zobellia galactanivorans TetR family transcriptional regulator YP_004739160.1 5487192 D 63186 CDS YP_004739161.1 340620708 10977092 complement(5487883..5489607) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5489607 10977092 zobellia_4747 Zobellia galactanivorans periplasmic protein YP_004739161.1 5487883 R 63186 CDS YP_004739162.1 340620709 10977093 5489707..5490264 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 5490264 10977093 zobellia_4748 Zobellia galactanivorans hypothetical protein YP_004739162.1 5489707 D 63186 CDS YP_004739163.1 340620710 10977094 5490378..5490842 1 NC_015844.1 SmpB binds specifically to the ssrA RNA and is required for stable association of ssrA with ribosomes. SsrA RNA recognizes ribosomes stalled on defective messages and acts as a tRNA and mRNA to mediate the addition of a short peptide tag to the C-terminus of the partially synthesized nascent polypeptide chain. The SsrA- tagged protein is then degraded by C-terminal-specific proteases. Formation of an SmpB-SsrA complex appears to be critical in mediating SsrA activity after aminoacylation with alanine but prior to the transpeptidation reaction that couples this alanine to the nascent chain. localized in the cytoplasm.; High confidence in function and specificity; SsrA-binding protein 5490842 smpB 10977094 smpB Zobellia galactanivorans SsrA-binding protein YP_004739163.1 5490378 D 63186 CDS YP_004739164.1 340620711 10978599 complement(5490855..5491469) 1 NC_015844.1 Protein-L-isoaspartate O-methyltransferase catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L- asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. This enzyme does not act on D-aspartyl residues. It uses S-adenosyl-L-methionine as a methyl donor. Localized in the cytoplasm.; High confidence in function and specificity; protein-L-isoaspartate O-methyltransferase 5491469 pcm 10978599 pcm Zobellia galactanivorans protein-L-isoaspartate O-methyltransferase YP_004739164.1 5490855 R 63186 CDS YP_004739165.1 340620712 10978314 5491659..5492618 1 NC_015844.1 NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold. Localized in the cytoplasm.; Specificity unclear; NAD(P)-dependent oxidoreductase 5492618 10978314 zobellia_4751 Zobellia galactanivorans NAD(P)-dependent oxidoreductase YP_004739165.1 5491659 D 63186 CDS YP_004739166.1 340620713 10977095 5492638..5493528 1 NC_015844.1 The 3-Hydroxybutyryl-CoA dehydrogenase is involved in butyrate/butanol-producing pathway. It converts the (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family; Localized in the cytoplasm; High confidence in function and specificity; 3-hydroxybutyryl-CoA dehydrogenase 5493528 hbdA 10977095 hbdA Zobellia galactanivorans 3-hydroxybutyryl-CoA dehydrogenase YP_004739166.1 5492638 D 63186 CDS YP_004739167.1 340620714 10977960 5493580..5494233 1 NC_015844.1 Conserved protein displaying similarity with the N-terminal domain of Alanine racemase which folds as a alpha/beta barrel (TIM barrel fold). Localized in cytoplasm.; Conserved hypothetical protein; alpha/beta barrel fold protein 5494233 10977960 zobellia_4753 Zobellia galactanivorans alpha/beta barrel fold protein YP_004739167.1 5493580 D 63186 CDS YP_004739168.1 340620715 10977096 5494287..5495657 1 NC_015844.1 Contains a N-terminal exonuclease domain found in ribonuclease T and the epsilon subunit of DNA polymerase III and, in the middle part, a GIY-YIG catalytic domain Localized in the cytoplasm; Function unclear; nuclease 5495657 10977096 zobellia_4754 Zobellia galactanivorans nuclease YP_004739168.1 5494287 D 63186 CDS YP_004739169.1 340620716 10977097 5495660..5496508 1 NC_015844.1 Conserved ion channel belonging to the sodium, Potassium, Calcium ion channel family. Its specificity is unknown. Features five transmembrane helices. Localized in the cytoplasmic membrane.; Specificity unclear; Ion channel 5496508 10977097 zobellia_4755 Zobellia galactanivorans Ion channel YP_004739169.1 5495660 D 63186 CDS YP_004739170.1 340620717 10977098 5496508..5497440 1 NC_015844.1 tRNA isopentenyltransferase catalyzes the first step in the biosynthesis of 2-methylthio-N6-(delta(2)-isopentenyl)-adenosine adjacent to the anticodon of several tRNA species. It catalyzes the reaction: Isopentenyl diphosphate + tRNA = diphosphate + tRNA containing 6-isopentenyladenosine. It forms a homodimer. Localized in the cytoplasm.; High confidence in function and specificity; tRNA isopentenyltransferase 5497440 miaA 10977098 miaA Zobellia galactanivorans tRNA isopentenyltransferase YP_004739170.1 5496508 D 63186 CDS YP_004739171.1 340620718 10978159 5497430..5497942 1 NC_015844.1 Gluconokinase is involved in the gluconate catabolism pathway (Pentose phosphate pathway). It converts the D-gluconate to 6-phospho-D-gluconate; GntK adopts an alpha/beta fold, consisting of a central sheet of five parallel beta-strands flanked by alpha-helices; Belongs to the shikimate kinase family; Localized in the cytoplasm; High confidence in function and specificity; gluconokinase 5497942 gntK2 10978159 gntK2 Zobellia galactanivorans gluconokinase YP_004739171.1 5497430 D 63186 CDS YP_004739172.1 340620719 10977942 complement(5497983..5498693) 1 NC_015844.1 The response regulator proteins are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of two domains, an N-terminal response regulator receiver domain that is substrate for a histidine protein kinase sensor, and a variable C-terminal effector domain with DNA-binding activity (here, a winged-helix DNA-binding domain) that acts as transcriptional regulator; Hypothetical protein; two-component system-response regulator 5498693 10977942 zobellia_4758 Zobellia galactanivorans two-component system-response regulator YP_004739172.1 5497983 R 63186 CDS YP_004739173.1 340620720 10977099 complement(5498705..5500285) 1 NC_015844.1 The sensor histidine kinase belongs to two-component signal transduction systems. It catalyzes the ATP dependent autophosphorylation of a conserved histidine in its phosphoacceptor domain and the signal dependent phosphorylation of a conserved aspartic acid present in the response regulator receiver domain; Contains two transmembrane segments; Localized in the cytoplasmic membrane; Family membership; two-component system-sensor histidine kinase 5500285 10977099 zobellia_4759 Zobellia galactanivorans two-component system-sensor histidine kinase YP_004739173.1 5498705 R 63186 CDS YP_004739174.1 340620721 10977100 complement(5500369..5500959) 1 NC_015844.1 Dephospho-CoA kinase catalyzes the final step in CoA biosynthesis, the phosphorylation of the 3'-hydroxyl group of ribose using ATP as a phosphate donor. It consists of three domains: the nucleotide-binding domain with a five-stranded parallel beta-sheet, the substrate- binding alpha-helical domain, and the lid domain formed by a pair of alpha-helices. Localized in the cytoplasm.; High confidence in function and specificity; Dephospho-CoA kinase 5500959 coaE 10977100 coaE Zobellia galactanivorans Dephospho-CoA kinase YP_004739174.1 5500369 R 63186 CDS YP_004739175.1 340620722 10977663 complement(5500956..5501867) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 5501867 10977663 zobellia_4761 Zobellia galactanivorans hypothetical protein YP_004739175.1 5500956 R 63186 CDS YP_004739176.1 340620723 10977101 complement(5501925..5502926) 1 NC_015844.1 Glycosyltransferase catalyzes the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. This enzyme belongs to the family 2 of the glycosyltransferases. Features two transmembrane helices in C-terminus. Localized in the cytoplasmic membrane.; Specificity unclear; glycosyltransferase 5502926 10977101 zobellia_4762 Zobellia galactanivorans glycosyltransferase YP_004739176.1 5501925 R 63186 CDS YP_004739177.1 340620724 10977102 complement(5503053..5503865) 1 NC_015844.1 FabI is a NADH-dependent enoyl-ACP reductase and is involved in fatty acid biosynthesis. It catalyzes the reaction : Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. It forms a homotetramer and binds A NAD+ per subunit. Localized in the cytoplasm.; High confidence in function and specificity; enoyl-ACP reductase (NADH) 5503865 fabI 10977102 fabI Zobellia galactanivorans enoyl-ACP reductase (NADH) YP_004739177.1 5503053 R 63186 CDS YP_004739178.1 340620725 10977808 complement(5504022..5505674) 1 NC_015844.1 RecN is involved in recombinational repair of damaged DNA. It appears to be an early detector of breaks in double-stranded DNA. In vivo, RecN forms discrete nucleoid-associated structures and in vitro exhibits Mg2+-dependent single-stranded (ss) DNA binding and ssDNA-dependent ATPase activities. Localized in the cytoplasm.; High confidence in function and specificity; DNA repair protein RecN 5505674 recN 10977808 recN Zobellia galactanivorans DNA repair protein RecN YP_004739178.1 5504022 R 63186 CDS YP_004739179.1 340620726 10978445 complement(5505730..5506617) 1 NC_015844.1 Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein; periplasmic protein 5506617 10978445 zobellia_4765 Zobellia galactanivorans periplasmic protein YP_004739179.1 5505730 R 63186 CDS YP_004739180.1 340620727 10977103 complement(5506610..5507815) 1 NC_015844.1 CoaBC catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine. It forms a homodecamer and binds one magnesium ion and one FMN as cofactor per subunit. Localized in the cytoplasm.; High confidence in function and specificity; Coenzyme A biosynthesis bifunctional protein coaBC 5507815 coaBC 10977103 coaBC Zobellia galactanivorans Coenzyme A biosynthesis bifunctional protein coaBC YP_004739180.1 5506610 R 63186 CDS YP_004739181.1 340620728 10977661 complement(5507819..5508151) 1 NC_015844.1 Conserved hypothetical protein. Localized in the cytoplasm.; hypothetical protein 5508151 10977661 zobellia_4767 Zobellia galactanivorans hypothetical protein YP_004739181.1 5507819 R 63186 CDS YP_004739182.1 340620729 10977104 complement(5508164..5509000) 1 NC_015844.1 Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 20 and 21; Localized in the outer membrane; Conserved hypothetical protein; lipoprotein 5509000 10977104 zobellia_4768 Zobellia galactanivorans lipoprotein YP_004739182.1 5508164 R 63186 CDS YP_004739183.1 340620730 10977105 complement(5509108..5509992) 1 NC_015844.1 Dihydropicolinate synthase (DHDPS) is the key enzyme in lysine biosynthesis via the diaminopimelate pathway of prokaryotes, some phycomycetes and higher plants. The enzyme catalyses the condensation of L- aspartate-beta-semialdehyde and pyruvate to dihydropicolinic acid via a ping-pong mechanism in which pyruvate binds to the enzyme by forming a Schiff-base with a lysine residue; localized in the cytoplasm; High confidence in function and specificity; dihydrodipicolinate synthetase 5509992 dapA2 10977105 dapA2 Zobellia galactanivorans dihydrodipicolinate synthetase YP_004739183.1 5509108 R 63186 CDS YP_004739184.1 340620731 10977715 complement(5509992..5510525) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5510525 10977715 zobellia_4770 Zobellia galactanivorans hypothetical protein YP_004739184.1 5509992 R 63186 CDS YP_004739185.1 340620732 10977107 5510629..5511396 1 NC_015844.1 The 5'nucleotidase is involved in the degradation of extracellular 5'-nucleotides into membrane permeable nucleosides. Usually it is composed of a N-terminal phosphatase domain and of a C-terminal alpha/beta fold domain with three conserved arginines which are involved in substrate binding and may also play a role in transition-state stabilization. This lipoprotein corresponds only to this latter domain; Signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane probably associated with the phosphatase subunit; Function unclear; 5'nucleotidase, substrate binding subunit 5511396 10977107 zobellia_4771 Zobellia galactanivorans 5'nucleotidase, substrate binding subunit YP_004739185.1 5510629 D 63186 CDS YP_004739186.1 340620733 10977108 5511455..5512366 1 NC_015844.1 The 5'-Nucleotidase is involved in the degradation of extracellular 5'-nucleotides into membrane permeable nucleosides. Usually It is composed of a N-terminal phosphatase domain that provides the ligands to the dimetal cluster and a conserved histidine, which together form the catalytic site and of a C-terminal domain involved in the substrate binding; This lipoprotein corresponds only to the phosphatase domain that hydrolyses the phosphate esterified at carbon 5' of the ribose and deoxyribose portions of nucleotide molecules; Binds a chloride ion and a magnesium ion as cofactors; Signal peptide cleaved between the residues 21 and 22; Localized in the outer membrane probably associated with the substrate binding subunit; High confidence in function and specificity; 5'-nucleotidase 5512366 nutA 10977108 nutA Zobellia galactanivorans 5'-nucleotidase YP_004739186.1 5511455 D 63186 CDS YP_004739187.1 340620734 10978284 5512369..5512821 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 5512821 10978284 zobellia_4773 Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004739187.1 5512369 D 63186 CDS YP_004739188.1 340620735 10977109 complement(5512813..5513124) 1 NC_015844.1 Localized in the cytoplasm; hypothetical protein 5513124 10977109 zobellia_4774 Zobellia galactanivorans hypothetical protein YP_004739188.1 5512813 R 63186 CDS YP_004739189.1 340620736 10977110 5513196..5514446 1 NC_015844.1 Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Hypothetical protein; hypothetical protein 5514446 10977110 zobellia_4775 Zobellia galactanivorans hypothetical protein YP_004739189.1 5513196 D 63186 CDS YP_004739190.1 340620737 10977111 complement(5514477..5516474) 1 NC_015844.1 DNA ligase catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'- hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Localized in the cytoplasm; High confidence in function and specificity; DNA ligase 5516474 ligA 10977111 ligA Zobellia galactanivorans DNA ligase YP_004739190.1 5514477 R 63186 CDS YP_004739191.1 340620738 10978090 complement(5516535..5517398) 1 NC_015844.1 Protein methyltransferase hemK plays a role in translational termination. It methylates at GGQ sites the translation termination release factors RF1 and RF2; Uses S-adenosylmethionine as cofactor; Localized in the cytoplasm; High confidence in function and specificity; protein methyltransferase HemK 5517398 hemK 10978090 hemK Zobellia galactanivorans protein methyltransferase HemK YP_004739191.1 5516535 R 63186 CDS YP_004739192.1 340620739 10977970 complement(5517417..5517893) 1 NC_015844.1 The N-Acetyltransferases catalyze the transfer of an acetyl group from acetyl-CoA to a substrate molecule; Belongs to Gcn5 or GNAT actyltransferase family; Localized in the cytoplasm; Family membership; GCN5-like N-acetyltransferase 5517893 yjgM 10977970 yjgM Zobellia galactanivorans GCN5-like N-acetyltransferase YP_004739192.1 5517417 R 63186 CDS YP_004739193.1 340620740 10978789 5517991..5519076 1 NC_015844.1 RibD is involved in the biosynthesis of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). It is a bifunctional enzyme catalyzing the second and third steps in the vitamin B2 biosynthesis: the deamination of 2,5-diamino-6-ribosylamino-4(3H)- pyrimidinone 5'-phosphate and the subsequent reduction of the ribosyl side chain; Contains a N-terminal diaminohydroxyphosphoribosylaminopyrimidine deaminase module belonging to the cytidine and deoxycytidylate deaminase family and a C-terminal 5-amino-6-(5-phosphoribosylamino)uracil reductase module belonging to the HTP reductase family; Localized in the cytoplasm; High confidence in function and specificity; riboflavin biosynthesis protein ribD 5519076 ribD 10978789 ribD Zobellia galactanivorans riboflavin biosynthesis protein ribD YP_004739193.1 5517991 D 63186 CDS YP_004739194.1 340620741 10978461 5519069..5519674 1 NC_015844.1 Phosphatase YihX catalyzes the dephosphorylation of the beta-glucose 1-phosphate; Belongs to the haloacid dehalogenase-like hydrolase family; Localized in the cytoplasm; Specificity unclear; phosphatase YihX 5519674 yihX 10978461 yihX Zobellia galactanivorans phosphatase YihX YP_004739194.1 5519069 D 63186 CDS YP_004739195.1 340620742 10978787 5519676..5520539 1 NC_015844.1 Protein containing two DUF6 family domain; Contains ten transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein; membrane protein 5520539 10978787 zobellia_4781 Zobellia galactanivorans membrane protein YP_004739195.1 5519676 D 63186 CDS YP_004739196.1 340620743 10977112 5520539..5521144 1 NC_015844.1 Protein belonging to the IMPACT ((Imprinted and ancient gene protein homolog) family (UPF0029 family); Localized in the cytoplasm; Family membership; hypothetical protein 5521144 10977112 zobellia_4782 Zobellia galactanivorans hypothetical protein YP_004739196.1 5520539 D 63186 CDS YP_004739197.1 340620744 10977113 complement(5521233..5521592) 1 NC_015844.1 Acyl-CoA thioester hydrolase is involved in fatty acid biosynthesis catalyzing the hydrolysis of the thioester bond in acyl-CoA to give the corresponding fatty acid and CoA; Localized in the cytoplasm; High confidence in function and specificity; acyl-CoA thioester hydrolase 5521592 ybgC2 10977113 ybgC2 Zobellia galactanivorans acyl-CoA thioester hydrolase YP_004739197.1 5521233 R 63186 CDS